Search of human proteins with 66932982

Search of human proteins with 66932982

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66932982 filamin-binding LIM protein-1 isoform a [Homo
sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]    805   0.0  
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]    634   0.0  
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]    440   e-123
gi|58530845 zyxin [Homo sapiens]                                      223   2e-58
gi|4508047 zyxin [Homo sapiens]                                       223   2e-58
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]     197   2e-50
gi|5031887 LIM domain containing preferred translocation partner...   196   4e-50
gi|7657307 LIM domains containing 1 [Homo sapiens]                    184   9e-47
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]         173   2e-43
gi|14249622 ajuba isoform 1 [Homo sapiens]                            172   6e-43
gi|109638745 transforming growth factor beta 1 induced transcrip...   121   9e-28
gi|21361591 transforming growth factor beta 1 induced transcript...   121   9e-28
gi|37675280 ajuba isoform 2 [Homo sapiens]                            114   1e-25
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            113   2e-25
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             113   2e-25
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            108   1e-23
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]            108   1e-23
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              100   2e-21
gi|170932518 paxillin isoform 3 [Homo sapiens]                        100   2e-21
gi|170932516 paxillin isoform 2 [Homo sapiens]                        100   2e-21
gi|170932514 paxillin isoform 1 [Homo sapiens]                        100   2e-21
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]              97   3e-20
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]              94   2e-19
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]    93   4e-19
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]    93   4e-19
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]    93   4e-19
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]    93   4e-19
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]     93   4e-19
gi|87159836 four and a half LIM domains 2 [Homo sapiens]               93   4e-19
gi|87159834 four and a half LIM domains 2 [Homo sapiens]               93   4e-19

>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score =  805 bits (2079), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
           MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1   MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60

Query: 61  SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
           SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE
Sbjct: 61  SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120

Query: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
           APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST
Sbjct: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180

Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
           DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL
Sbjct: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240

Query: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 300
           ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 300

Query: 301 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 360
           PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC
Sbjct: 301 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 360

Query: 361 KPCHVKRSAAGCC 373
           KPCHVKRSAAGCC
Sbjct: 361 KPCHVKRSAAGCC 373


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score =  634 bits (1635), Expect = 0.0
 Identities = 298/304 (98%), Positives = 300/304 (98%)

Query: 1   MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
           MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1   MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60

Query: 61  SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
           SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE
Sbjct: 61  SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120

Query: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
           APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST
Sbjct: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180

Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
           DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL
Sbjct: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240

Query: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 300
           ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR   
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 300

Query: 301 PVCS 304
            +C+
Sbjct: 301 GLCT 304



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 361
           +C+ C   + PR+      +E M R +H  C+ C  CR  L+     Q  Y  +    C+
Sbjct: 182 ICAFCHKTVSPRE----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233

Query: 362 PCH 364
           PC+
Sbjct: 234 PCY 236


>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
          Length = 276

 Score =  440 bits (1131), Expect = e-123
 Identities = 202/232 (87%), Positives = 208/232 (89%), Gaps = 1/232 (0%)

Query: 142 PPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMK 201
           P P + P  G + +P P           PA P++   + DICAFCHKTVSPRELAVEAMK
Sbjct: 46  PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL-FNGDICAFCHKTVSPRELAVEAMK 104

Query: 202 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 261
           RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA
Sbjct: 105 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 164

Query: 262 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 321
           FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI
Sbjct: 165 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 224

Query: 322 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 373
           ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
Sbjct: 225 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 276



 Score =  171 bits (433), Expect = 1e-42
 Identities = 83/83 (100%), Positives = 83/83 (100%)

Query: 1  MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
          MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1  MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60

Query: 61 SPWTTPGRAAATVPAAPMQLFNG 83
          SPWTTPGRAAATVPAAPMQLFNG
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNG 83


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score =  223 bits (569), Expect = 2e-58
 Identities = 105/271 (38%), Positives = 150/271 (55%), Gaps = 19/271 (7%)

Query: 108 PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPME---- 163
           P PP      + E P           E+ H  PPP   Q     P   PGPL   E    
Sbjct: 309 PQPPSFTYAQQREKPRVQ--------EKQHPVPPPAQNQNQVRSPGA-PGPLTLKEVEEL 359

Query: 164 EELPPPPAEPVEKG-----ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
           E+L     + +E       A  ++C  CH+ ++  + AV A+ + +H  CFTC  C +QL
Sbjct: 360 EQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQL 419

Query: 219 AGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
            GQ FY  +G P CE CY DTLE+C  CGE + D ++RA G+A+HP CFTCV CAR +  
Sbjct: 420 QGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEG 479

Query: 279 ESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCED 337
            SF +   N  +C+ D+++++AP CS+C  PI+P  G+D   ++  + +NFH  CY+CED
Sbjct: 480 TSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCED 539

Query: 338 CRILLSVEPTDQGCYPLNNHLFCKPCHVKRS 368
           C   LS+E  D GC+PL+ H+ C+ CH  R+
Sbjct: 540 CGKPLSIEADDNGCFPLDGHVLCRKCHTARA 570



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 54/172 (31%), Positives = 71/172 (41%), Gaps = 32/172 (18%)

Query: 17  LAPPRRDVAVAEEVRQAVCEARRGR--PWEAPAPMKTPEAGLAGRPSPWTTPGRA----A 70
           +A PR   A++  V      A + +  P  AP P   P       P P     RA     
Sbjct: 1   MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60

Query: 71  ATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLI 130
             +P  P + F    PPPP   DG+D    L    PPPPPP      E   PAP+     
Sbjct: 61  GEIPPPPPEDFP--LPPPPLAGDGDDAEGALGGAFPPPPPP----IEESFPPAPLE---- 110

Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI 182
              E++  SPPPPP +        + GP  P+     PPP +P EK +S D+
Sbjct: 111 ---EEIFPSPPPPPEE--------EGGPEAPI-----PPPPQPREKVSSIDL 146


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score =  223 bits (569), Expect = 2e-58
 Identities = 105/271 (38%), Positives = 150/271 (55%), Gaps = 19/271 (7%)

Query: 108 PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPME---- 163
           P PP      + E P           E+ H  PPP   Q     P   PGPL   E    
Sbjct: 309 PQPPSFTYAQQREKPRVQ--------EKQHPVPPPAQNQNQVRSPGA-PGPLTLKEVEEL 359

Query: 164 EELPPPPAEPVEKG-----ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
           E+L     + +E       A  ++C  CH+ ++  + AV A+ + +H  CFTC  C +QL
Sbjct: 360 EQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQL 419

Query: 219 AGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
            GQ FY  +G P CE CY DTLE+C  CGE + D ++RA G+A+HP CFTCV CAR +  
Sbjct: 420 QGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEG 479

Query: 279 ESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCED 337
            SF +   N  +C+ D+++++AP CS+C  PI+P  G+D   ++  + +NFH  CY+CED
Sbjct: 480 TSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCED 539

Query: 338 CRILLSVEPTDQGCYPLNNHLFCKPCHVKRS 368
           C   LS+E  D GC+PL+ H+ C+ CH  R+
Sbjct: 540 CGKPLSIEADDNGCFPLDGHVLCRKCHTARA 570



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 54/172 (31%), Positives = 71/172 (41%), Gaps = 32/172 (18%)

Query: 17  LAPPRRDVAVAEEVRQAVCEARRGR--PWEAPAPMKTPEAGLAGRPSPWTTPGRA----A 70
           +A PR   A++  V      A + +  P  AP P   P       P P     RA     
Sbjct: 1   MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60

Query: 71  ATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLI 130
             +P  P + F    PPPP   DG+D    L    PPPPPP      E   PAP+     
Sbjct: 61  GEIPPPPPEDFP--LPPPPLAGDGDDAEGALGGAFPPPPPP----IEESFPPAPLE---- 110

Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI 182
              E++  SPPPPP +        + GP  P+     PPP +P EK +S D+
Sbjct: 111 ---EEIFPSPPPPPEE--------EGGPEAPI-----PPPPQPREKVSSIDL 146


>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
          Length = 476

 Score =  197 bits (500), Expect = 2e-50
 Identities = 120/339 (35%), Positives = 163/339 (48%), Gaps = 29/339 (8%)

Query: 46  PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG----GCPPPPPVLDGEDVLPDL 101
           P P     A   G P+P +    +    PA P+Q+       GC PP             
Sbjct: 138 PNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRGCGPPRR---------GA 188

Query: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLI-----ADLEQLHLSPPPPPPQAPAEGPSVQP 156
                P P P   LP   E   P   S       A  E   +S P    +    GP V  
Sbjct: 189 SQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQV-- 246

Query: 157 GPL-RPMEEELPPPPAEPVE------KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCF 209
            PL +P E+EL     + V        G     C  C + V      V A+ R +H  CF
Sbjct: 247 -PLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCF 305

Query: 210 TCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTC 269
            C TCR QL GQ FY  + R  CE CY  TLE+C  C + + D I+RA+G+A+HP CFTC
Sbjct: 306 VCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFTC 365

Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNF 328
           V C R +    F + + ++++C++DF+RKFAP CS+C   I+P  G ++  +I  + R+F
Sbjct: 366 VVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSF 425

Query: 329 HENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKR 367
           H  CY+CE+C +LLS E   QGCYPL+ H+ CK C   R
Sbjct: 426 HIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWR 464


>gi|5031887 LIM domain containing preferred translocation partner in
           lipoma [Homo sapiens]
          Length = 612

 Score =  196 bits (497), Expect = 4e-50
 Identities = 96/242 (39%), Positives = 135/242 (55%), Gaps = 13/242 (5%)

Query: 138 LSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI-----------CAFC 186
           +S P  PP  P  G S Q GP        P    E + K    D+           CA C
Sbjct: 360 VSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARC 419

Query: 187 HKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKC 246
            + V        AM + +H  CFTC  C  +L GQ FY  + +  CEPCY +TLE+C  C
Sbjct: 420 GENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVC 479

Query: 247 GEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSIC 306
            + + + I+RA G+A+HP CFTCV C R +    F + +   ++C++DF++KFAP CS+C
Sbjct: 480 SKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVC 539

Query: 307 ENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHV 365
           + PI+P  G ++  +I  + R+FH +CYRCEDC  LLS E  +QGCYPL+ H+ CK C+ 
Sbjct: 540 KEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNS 598

Query: 366 KR 367
            R
Sbjct: 599 AR 600



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 17/92 (18%)

Query: 86  PPPPPVLDGEDVLPDLDLLPPPPPP----------PPVLLPSEE-----EAPAPMGASLI 130
           PPPPP LD    LP +    PPPPP           P     EE     +A      S++
Sbjct: 69  PPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSIL 128

Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
           ADLE    SP  P P   + G +  P    P+
Sbjct: 129 ADLE--CSSPYKPRPPQSSTGSTASPPVSTPV 158



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 40/167 (23%), Positives = 58/167 (34%), Gaps = 51/167 (30%)

Query: 47  APMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL--------FNGGCPPPPPV------- 91
           AP+  P+     + +P+  PG     +P  P  L         +G  PPPPP+       
Sbjct: 46  APVVAPKP----KYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKV 101

Query: 92  ---------------LDGE-----DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA 131
                          LD E      +L DL+   P  P PP        +P P+   +  
Sbjct: 102 QGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASP-PVSTPVTG 160

Query: 132 DLEQLHLSPPP---------PPPQAPAEGP-SVQP-GPLRPMEEELP 167
               +  + PP          P  AP  GP  V P G L+P  + +P
Sbjct: 161 HKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVP 207


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score =  184 bits (468), Expect = 9e-47
 Identities = 111/330 (33%), Positives = 160/330 (48%), Gaps = 23/330 (6%)

Query: 60  PSPWTTPGRAAATVPAAPMQL---FNGGCPPPPPVLDGEDVLPDLDLLPPPPPPP---PV 113
           P PW   G  +    +AP       +G      P L  +    DL   P   P     PV
Sbjct: 333 PQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPV 392

Query: 114 L--LPSEEEAPAPMGASLIADLEQLHL-SPPPPPPQAPAE----GPSVQPGPLRPMEEEL 166
           +  LP       P+G S    L  + L SP  P  + P +    GP ++P       E L
Sbjct: 393 MSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLEAL 452

Query: 167 PPPPAEPVEKGASTDI---CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF 223
                  ++     D    C  C K V     A +AM   YH  CFTC  C R+L G++F
Sbjct: 453 TQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAF 512

Query: 224 YQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
           Y  +G+  CE  +     Q + +RC  CG ++ D I++ALG+++HP CF CV C  C+  
Sbjct: 513 YFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDG 572

Query: 279 ESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCED 337
             F + S+N++YC+ D+++  AP C+ C  PI+P +G D   ++  M R++H  CY CED
Sbjct: 573 VPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCED 632

Query: 338 CRILLSVEPTDQGCYPLNNHLFCKPCHVKR 367
           C + L+ E   + CYPL +HLFC  CHVKR
Sbjct: 633 CGLELNDEDGHR-CYPLEDHLFCHSCHVKR 661


>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
          Length = 430

 Score =  173 bits (439), Expect = 2e-43
 Identities = 94/279 (33%), Positives = 136/279 (48%), Gaps = 27/279 (9%)

Query: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP 161
           D LPP   P P   P E   PAP               P  P P     GPS     L  
Sbjct: 158 DFLPPGACPAPARSP-EPAGPAPFPL------------PALPLPPGREGGPSAAERRLEA 204

Query: 162 MEEELPPPPAEPVEKGASTD---ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
           +  EL       +E   + D   IC  C   +   + A +AM   YH  CFTC +C R+L
Sbjct: 205 LTRELE----RALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRL 260

Query: 219 AGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCA 273
            G++FY    +  C+  +     Q T ++C  CG ++ + I++ALG+++HP CF C  C 
Sbjct: 261 RGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCN 320

Query: 274 RCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNFHENC 332
            C+    F +  +N +YC+ D++  FAP C+ C  PI+P  G +   ++  M R++H  C
Sbjct: 321 ECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVAC 380

Query: 333 YRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAG 371
           Y CEDC + LS E   + CYPL  HL C+ CH++R   G
Sbjct: 381 YHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQPG 418


>gi|14249622 ajuba isoform 1 [Homo sapiens]
          Length = 538

 Score =  172 bits (435), Expect = 6e-43
 Identities = 82/235 (34%), Positives = 129/235 (54%), Gaps = 21/235 (8%)

Query: 151 GPSVQPGPLRPMEEELPPPP----------AEPVEKGASTDICAFCHKTVSPRELAVEAM 200
           G   +P  + P   E PP P           EP  +      C  C+K +  +  A +A+
Sbjct: 296 GARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355

Query: 201 KRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHII 255
              YH QCF C +C R L  ++FY  +G   CE  Y     Q+  E+C  CG ++ + I+
Sbjct: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415

Query: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG 315
           +A+G+++HP CF C+ C +C+    F +   N+VYC+ D+++ +AP C+ C  PI+P +G
Sbjct: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG 475

Query: 316 -KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 367
            +D  ++  M R++H  CY CEDCR+ LS E   +G  C+PL+ HL C  CH++R
Sbjct: 476 CEDIVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 527



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)

Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
           CA C + + P E     + V +M R YH +C+ C  CR QL+   G   +  DG  LC  
Sbjct: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522

Query: 235 CYQDTL 240
           C+   L
Sbjct: 523 CHMQRL 528


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  121 bits (304), Expect = 9e-28
 Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 36/249 (14%)

Query: 115 LPSEEEAPAPMGASLIADLE----QLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPP 170
           LPS      P  ++  A LE       LS        PA GP+ QP  +    E  P PP
Sbjct: 138 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPT-QPPVVSSTNEGSPSPP 196

Query: 171 AEPVEKGA--------------------STDICAFCHKTVSPRELAVEAMKRQYHAQCFT 210
            EP  KG+                    +  +C  C+K ++ +   V A+ R +H + F 
Sbjct: 197 -EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQ--VVTALGRAWHPEHFV 253

Query: 211 CRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTC 269
           C  C   L G SF++KDG P C  CY +    RCG C + +R  ++ ALG  +HP  F C
Sbjct: 254 CGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCC 313

Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFH 329
           V+C    GDE F    +   YC  DF + FAP C  C+ PI+         I  +   +H
Sbjct: 314 VSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQGPILDN------YISALSALWH 366

Query: 330 ENCYRCEDC 338
            +C+ C +C
Sbjct: 367 PDCFVCREC 375



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 241
           C FC++ +  R   V A+   +H + F C +C      + F++++GRP C   + Q    
Sbjct: 287 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 344

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           RC  C   + D+ I AL   +HP CF C  C       SF    +    C + F+ +   
Sbjct: 345 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 403

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 360
           +C+ C  P+  R       +  +GR FH + + C  C     + P  +G +       +C
Sbjct: 404 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 452

Query: 361 KPCHVK 366
           +PC +K
Sbjct: 453 QPCFLK 458



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)

Query: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 255
           + A+   +H  CF CR C    +G SF++ +GRPLCE  +       C  CG  V    +
Sbjct: 358 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 417

Query: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
            ALG+ FHP  FTC  C R +   SF      + YC   F + F
Sbjct: 418 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  121 bits (304), Expect = 9e-28
 Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 36/249 (14%)

Query: 115 LPSEEEAPAPMGASLIADLE----QLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPP 170
           LPS      P  ++  A LE       LS        PA GP+ QP  +    E  P PP
Sbjct: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPT-QPPVVSSTNEGSPSPP 179

Query: 171 AEPVEKGA--------------------STDICAFCHKTVSPRELAVEAMKRQYHAQCFT 210
            EP  KG+                    +  +C  C+K ++ +   V A+ R +H + F 
Sbjct: 180 -EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQ--VVTALGRAWHPEHFV 236

Query: 211 CRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTC 269
           C  C   L G SF++KDG P C  CY +    RCG C + +R  ++ ALG  +HP  F C
Sbjct: 237 CGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCC 296

Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFH 329
           V+C    GDE F    +   YC  DF + FAP C  C+ PI+         I  +   +H
Sbjct: 297 VSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQGPILDN------YISALSALWH 349

Query: 330 ENCYRCEDC 338
            +C+ C +C
Sbjct: 350 PDCFVCREC 358



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 241
           C FC++ +  R   V A+   +H + F C +C      + F++++GRP C   + Q    
Sbjct: 270 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           RC  C   + D+ I AL   +HP CF C  C       SF    +    C + F+ +   
Sbjct: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 386

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 360
           +C+ C  P+  R       +  +GR FH + + C  C     + P  +G +       +C
Sbjct: 387 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 435

Query: 361 KPCHVK 366
           +PC +K
Sbjct: 436 QPCFLK 441



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)

Query: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 255
           + A+   +H  CF CR C    +G SF++ +GRPLCE  +       C  CG  V    +
Sbjct: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 400

Query: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
            ALG+ FHP  FTC  C R +   SF      + YC   F + F
Sbjct: 401 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 443


>gi|37675280 ajuba isoform 2 [Homo sapiens]
          Length = 121

 Score =  114 bits (286), Expect = 1e-25
 Identities = 46/113 (40%), Positives = 74/113 (65%), Gaps = 6/113 (5%)

Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-K 316
           +G+++HP CF C+ C +C+    F +   N+VYC+ D+++ +AP C+ C  PI+P +G +
Sbjct: 1   MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60

Query: 317 DAFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 367
           D  ++  M R++H  CY CEDCR+ LS E   +G  C+PL+ HL C  CH++R
Sbjct: 61  DIVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 110



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 17/93 (18%)

Query: 200 MKRQYHAQCFTCRTCRRQLAGQSF-------------YQKDGRPLCEPCYQDTLERCGKC 246
           M + YH  CF C  C + L G  F             Y K+  P C  C Q  L   G C
Sbjct: 1   MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG-C 59

Query: 247 GEVVRDHIIRALGQAFHPSCFTCVTCARCIGDE 279
            ++VR   + ++ + +H  C+ C  C   + DE
Sbjct: 60  EDIVR---VISMDRDYHFECYHCEDCRMQLSDE 89



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)

Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
           CA C + + P E     + V +M R YH +C+ C  CR QL+   G   +  DG  LC  
Sbjct: 46  CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 105

Query: 235 CYQDTL 240
           C+   L
Sbjct: 106 CHMQRL 111


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  113 bits (283), Expect = 2e-25
 Identities = 88/305 (28%), Positives = 127/305 (41%), Gaps = 31/305 (10%)

Query: 45  APAPMKTPEAGLAGRPSPWTT--PGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLD 102
           +PAP  TP    A  PSP  T  P  A A  P+ P   +N   P P     G        
Sbjct: 322 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS-PAPNYN---PAPSVAYSGGPA----- 372

Query: 103 LLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
              P   PP V   S  +  AP  ++     + L   P   P   PA GP V P     +
Sbjct: 373 --EPASRPPWVTDDSFSQKFAPGKSTTSISKQTL---PRGGPAYTPA-GPQVPPLARGTV 426

Query: 163 EEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS 222
           +       AE     + T +C  C+  +  R   + AM R +H + FTC  C+  LA   
Sbjct: 427 QR------AERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 478

Query: 223 FYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
           F ++     CE CY+      C KC   +   ++ AL Q +H +CF C  C +  G+  F
Sbjct: 479 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 538

Query: 282 ALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRIL 341
            +    E YC  D+   F+  C  C+ P+   +  D F IE +G  +H+ C+ C  C + 
Sbjct: 539 HM-EDGEPYCEKDYINLFSTKCHGCDFPV---EAGDKF-IEALGHTWHDTCFICAVCHVN 593

Query: 342 LSVEP 346
           L  +P
Sbjct: 594 LEGQP 598



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 83/349 (23%), Positives = 122/349 (34%), Gaps = 59/349 (16%)

Query: 38  RRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPP---PPVLDG 94
           RR RP    A   +P    +  P+  T+     A     P  +      P    P     
Sbjct: 249 RRSRP---QASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 305

Query: 95  EDVLPDLDLLPPP--PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGP 152
               P  +  P P  P P P   PS   A  P              +P P P   P+  P
Sbjct: 306 YSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTY--------TPSPAPAYTPSPAP 357

Query: 153 SVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCR 212
           +  P P           PAEP  +       +F  K  +P +      K+          
Sbjct: 358 NYNPAP----SVAYSGGPAEPASRPPWVTDDSFSQK-FAPGKSTTSISKQ---------- 402

Query: 213 TCRRQLAGQSFYQKDGRPLCEPCYQDTLER------------CGKCGEVVRDHIIRALGQ 260
           T  R   G   Y   G P   P  + T++R            CG C  V+R   + A+G+
Sbjct: 403 TLPR---GGPAYTPAG-PQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGR 458

Query: 261 AFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFK 320
           ++HP  FTC  C   + D  F +  QN VYC   + + FAP+C+ C   I+         
Sbjct: 459 SWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFFAPLCAKCNTKIMGE------V 511

Query: 321 IECMGRNFHENCYRCEDCR-----ILLSVEPTDQGCYPLNNHLFCKPCH 364
           +  + + +H  C+ C  C+      L  +E  +  C     +LF   CH
Sbjct: 512 MHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 560



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 20/51 (39%), Positives = 25/51 (49%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           C  C   V   +  +EA+   +H  CF C  C   L GQ FY K  RPLC+
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  113 bits (283), Expect = 2e-25
 Identities = 88/305 (28%), Positives = 127/305 (41%), Gaps = 31/305 (10%)

Query: 45  APAPMKTPEAGLAGRPSPWTT--PGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLD 102
           +PAP  TP    A  PSP  T  P  A A  P+ P   +N   P P     G        
Sbjct: 432 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS-PAPNYN---PAPSVAYSGGPA----- 482

Query: 103 LLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
              P   PP V   S  +  AP  ++     + L   P   P   PA GP V P     +
Sbjct: 483 --EPASRPPWVTDDSFSQKFAPGKSTTSISKQTL---PRGGPAYTPA-GPQVPPLARGTV 536

Query: 163 EEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS 222
           +       AE     + T +C  C+  +  R   + AM R +H + FTC  C+  LA   
Sbjct: 537 QR------AERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 588

Query: 223 FYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
           F ++     CE CY+      C KC   +   ++ AL Q +H +CF C  C +  G+  F
Sbjct: 589 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 648

Query: 282 ALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRIL 341
            +    E YC  D+   F+  C  C+ P+   +  D F IE +G  +H+ C+ C  C + 
Sbjct: 649 HM-EDGEPYCEKDYINLFSTKCHGCDFPV---EAGDKF-IEALGHTWHDTCFICAVCHVN 703

Query: 342 LSVEP 346
           L  +P
Sbjct: 704 LEGQP 708



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 86/372 (23%), Positives = 129/372 (34%), Gaps = 59/372 (15%)

Query: 18  APPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKT---PEAGLAGRPSPWTTPGRAAATVP 74
           +PP    A    +  A   A    P ++P P  +   P    +  P+  T+     A   
Sbjct: 333 SPPLATAAAHTAIASASTTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPA 392

Query: 75  AAPMQLFNGGCPPP---PPVLDGEDVLPDLDLLPPP--PPPPPVLLPSEEEAPAPMGASL 129
             P  +      P    P         P  +  P P  P P P   PS   A  P     
Sbjct: 393 PKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPT 452

Query: 130 IADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKT 189
                    +P P P   P+  P+  P P           PAEP  +       +F  K 
Sbjct: 453 Y--------TPSPAPAYTPSPAPNYNPAP----SVAYSGGPAEPASRPPWVTDDSFSQK- 499

Query: 190 VSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER------- 242
            +P +      K+          T  R   G   Y   G P   P  + T++R       
Sbjct: 500 FAPGKSTTSISKQ----------TLPR---GGPAYTPAG-PQVPPLARGTVQRAERFPAS 545

Query: 243 -----CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
                CG C  V+R   + A+G+++HP  FTC  C   + D  F +  QN VYC   + +
Sbjct: 546 SRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQ 604

Query: 298 KFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCR-----ILLSVEPTDQGCY 352
            FAP+C+ C   I+         +  + + +H  C+ C  C+      L  +E  +  C 
Sbjct: 605 FFAPLCAKCNTKIMGE------VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 658

Query: 353 PLNNHLFCKPCH 364
               +LF   CH
Sbjct: 659 KDYINLFSTKCH 670



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 20/51 (39%), Positives = 25/51 (49%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           C  C   V   +  +EA+   +H  CF C  C   L GQ FY K  RPLC+
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719



 Score = 29.3 bits (64), Expect = 6.0
 Identities = 24/106 (22%), Positives = 37/106 (34%), Gaps = 9/106 (8%)

Query: 106 PPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP---- 161
           PP   P  ++P +++       SL+A          P  P  P   P+  P   RP    
Sbjct: 94  PPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFS 153

Query: 162 --MEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYH 205
              E   P PP   +    S +        + P+ L   +  RQY+
Sbjct: 154 SLAEASDPGPPRASLRAKTSPE---GARDLLGPKALPGSSQPRQYN 196


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  108 bits (269), Expect = 1e-23
 Identities = 58/183 (31%), Positives = 91/183 (49%), Gaps = 8/183 (4%)

Query: 157 GPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRR 216
           G  +P +++     AE +  G  T +CA C++ +  R   + A+ + +H + F C  C+ 
Sbjct: 285 GQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCKN 342

Query: 217 QLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARC 275
            +A   F ++ G   CE CY+      CG+C   +   +I AL Q +H SCF CV C + 
Sbjct: 343 TMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKP 402

Query: 276 IGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRC 335
           I +  F L    E YC  D+Y  F  +C  CE PI   +  D F +E +G  +H+ C+ C
Sbjct: 403 IRNNVFHL-EDGEPYCETDYYALFGTICHGCEFPI---EAGDMF-LEALGYTWHDTCFVC 457

Query: 336 EDC 338
             C
Sbjct: 458 SVC 460



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C + +      + A+K+ +H  CF C  C + +    F+ +DG P CE  Y      
Sbjct: 370 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427

Query: 243 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 281
            C  C   +   D  + ALG  +H +CF C  C   +  ++F
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 469



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           IC  C   +   ++ +EA+   +H  CF C  C   L GQ+F+ K  +PLC+
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score =  108 bits (269), Expect = 1e-23
 Identities = 58/183 (31%), Positives = 91/183 (49%), Gaps = 8/183 (4%)

Query: 157 GPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRR 216
           G  +P +++     AE +  G  T +CA C++ +  R   + A+ + +H + F C  C+ 
Sbjct: 394 GQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCKN 451

Query: 217 QLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARC 275
            +A   F ++ G   CE CY+      CG+C   +   +I AL Q +H SCF CV C + 
Sbjct: 452 TMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKP 511

Query: 276 IGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRC 335
           I +  F L    E YC  D+Y  F  +C  CE PI   +  D F +E +G  +H+ C+ C
Sbjct: 512 IRNNVFHL-EDGEPYCETDYYALFGTICHGCEFPI---EAGDMF-LEALGYTWHDTCFVC 566

Query: 336 EDC 338
             C
Sbjct: 567 SVC 569



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C + +      + A+K+ +H  CF C  C + +    F+ +DG P CE  Y      
Sbjct: 479 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536

Query: 243 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 281
            C  C   +   D  + ALG  +H +CF C  C   +  ++F
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 578



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           IC  C   +   ++ +EA+   +H  CF C  C   L GQ+F+ K  +PLC+
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  100 bits (250), Expect = 2e-21
 Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 8/182 (4%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C+ C +TV P    +E   + +H  CF C  C + L  +SF    G   C PCY++    
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           RC +C + +    +    Q +H  C  C  C   +  + F      + YC+  F   FAP
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFT-SRDEDPYCVACFGELFAP 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 361
            CS C+ PI+   G      E   R++H NC+ C  C    S     QG  P  + + C+
Sbjct: 220 KCSSCKRPIVGLGGGKYVSFE--DRHWHHNCFSCARC----STSLVGQGFVPDGDQVLCQ 273

Query: 362 PC 363
            C
Sbjct: 274 GC 275



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 14/171 (8%)

Query: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRAL---GQA 261
           ++ F C  C   L G+ + Q D  P C PCY +T    C +C +++  H  R L    + 
Sbjct: 2   SESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLI-GHDSRELFYEDRH 60

Query: 262 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 321
           FH  CF C  C R + DE F     +E+ C D +   F+  CS C   ++P     + K+
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTC-QDSELLCNDCYCSAFSSQCSACGETVMP----GSRKL 115

Query: 322 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
           E  G+ +HE+C+ C  C   L      +   P     +C PC+  + A  C
Sbjct: 116 EYGGQTWHEHCFLCSGCEQPLG----SRSFVPDKGAHYCVPCYENKFAPRC 162



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 57/205 (27%), Positives = 81/205 (39%), Gaps = 19/205 (9%)

Query: 169 PPAEPVEKGASTDICAFCHKTVS--PRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQK 226
           P   P       + CA C + +    REL  E   R +H  CF C  C+R LA + F  +
Sbjct: 26  PYCVPCYDNTFANTCAECQQLIGHDSRELFYE--DRHFHEGCFRCCRCQRSLADEPFTCQ 83

Query: 227 DGRPLCEPCYQDTL-ERCGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESFAL 283
           D   LC  CY      +C  CGE V      +   GQ +H  CF C  C + +G  SF +
Sbjct: 84  DSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSF-V 142

Query: 284 GSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
             +   YC+  +  KFAP C+ C   +          +    + +H  C  C  C+  L+
Sbjct: 143 PDKGAHYCVPCYENKFAPRCARCSKTLTQGG------VTYRDQPWHRECLVCTGCQTPLA 196

Query: 344 VE-----PTDQGCYPLNNHLFCKPC 363
            +       D  C      LF   C
Sbjct: 197 GQQFTSRDEDPYCVACFGELFAPKC 221



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 14/36 (38%), Positives = 18/36 (50%)

Query: 202 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQ 237
           R +H  CF+C  C   L GQ F     + LC+ C Q
Sbjct: 242 RHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  100 bits (249), Expect = 2e-21
 Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 18/201 (8%)

Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
           SPP  PP+  ++  S+    L  ++ +L       V KG    +C  C K ++ +   V 
Sbjct: 155 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 204

Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
           AM + +H + F C  C+ ++  ++F+++DG+P CE  Y +    RC  C   + D ++ A
Sbjct: 205 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 264

Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD 317
           L + +HP  F C  C    G E F      + YC  D++  FAP C  C   I+      
Sbjct: 265 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILEN---- 319

Query: 318 AFKIECMGRNFHENCYRCEDC 338
              I  +   +H  C+ C +C
Sbjct: 320 --YISALNTLWHPECFVCREC 338



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
           C +C+  +  +   V A+ R +H + F C  C      + F++KDG+  C   Y D    
Sbjct: 250 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 307

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           +CG C   + ++ I AL   +HP CF C  C     + SF      + YC   ++ +   
Sbjct: 308 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 366

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 360
           +CS C+ PI  R       I  M + FH   + C  C     ++  ++G +   N+  +C
Sbjct: 367 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 415

Query: 361 KPCHVK 366
           + C +K
Sbjct: 416 QNCFLK 421



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C + +   E  + A+   +H +CF CR C       SF++ DG+P CE  Y +    
Sbjct: 309 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
            C  C + +    I A+ + FHP  F C  C + +   +F     ++ YC + F + F
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 423


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  100 bits (249), Expect = 2e-21
 Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 18/201 (8%)

Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
           SPP  PP+  ++  S+    L  ++ +L       V KG    +C  C K ++ +   V 
Sbjct: 288 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 337

Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
           AM + +H + F C  C+ ++  ++F+++DG+P CE  Y +    RC  C   + D ++ A
Sbjct: 338 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 397

Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD 317
           L + +HP  F C  C    G E F      + YC  D++  FAP C  C   I+      
Sbjct: 398 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILEN---- 452

Query: 318 AFKIECMGRNFHENCYRCEDC 338
              I  +   +H  C+ C +C
Sbjct: 453 --YISALNTLWHPECFVCREC 471



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
           C +C+  +  +   V A+ R +H + F C  C      + F++KDG+  C   Y D    
Sbjct: 383 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 440

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           +CG C   + ++ I AL   +HP CF C  C     + SF      + YC   ++ +   
Sbjct: 441 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 499

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 360
           +CS C+ PI  R       I  M + FH   + C  C     ++  ++G +   N+  +C
Sbjct: 500 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 548

Query: 361 KPCHVK 366
           + C +K
Sbjct: 549 QNCFLK 554



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C + +   E  + A+   +H +CF CR C       SF++ DG+P CE  Y +    
Sbjct: 442 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
            C  C + +    I A+ + FHP  F C  C + +   +F     ++ YC + F + F
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 556


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  100 bits (249), Expect = 2e-21
 Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 18/201 (8%)

Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
           SPP  PP+  ++  S+    L  ++ +L       V KG    +C  C K ++ +   V 
Sbjct: 322 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 371

Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
           AM + +H + F C  C+ ++  ++F+++DG+P CE  Y +    RC  C   + D ++ A
Sbjct: 372 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 431

Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKD 317
           L + +HP  F C  C    G E F      + YC  D++  FAP C  C   I+      
Sbjct: 432 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILEN---- 486

Query: 318 AFKIECMGRNFHENCYRCEDC 338
              I  +   +H  C+ C +C
Sbjct: 487 --YISALNTLWHPECFVCREC 505



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
           C +C+  +  +   V A+ R +H + F C  C      + F++KDG+  C   Y D    
Sbjct: 417 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 474

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           +CG C   + ++ I AL   +HP CF C  C     + SF      + YC   ++ +   
Sbjct: 475 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 533

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 360
           +CS C+ PI  R       I  M + FH   + C  C     ++  ++G +   N+  +C
Sbjct: 534 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 582

Query: 361 KPCHVK 366
           + C +K
Sbjct: 583 QNCFLK 588



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C + +   E  + A+   +H +CF CR C       SF++ DG+P CE  Y +    
Sbjct: 476 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
            C  C + +    I A+ + FHP  F C  C + +   +F     ++ YC + F + F
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 590


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 92/372 (24%), Positives = 134/372 (36%), Gaps = 92/372 (24%)

Query: 39  RGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPPP---PVLDGE 95
           + +P +A AP        A  P  +T     +    A P      G PPP    P  +G+
Sbjct: 88  QSKPQKASAP--------AADPPRYTFAPSVSLNKTARPF-----GAPPPADSAPQQNGQ 134

Query: 96  DVLPDLDLLPPPPPPPPVLLPSEEEAPAP--------------MGASLIADLEQLHL--S 139
            + P    L P      ++  +E+  P P               G   + D ++ HL  S
Sbjct: 135 PLRP----LVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKS 190

Query: 140 PPPPPPQAPAEGPSVQ----PGPLRPMEEELPP------------------------PPA 171
              P  +APA   S      PGP  P     PP                         PA
Sbjct: 191 SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPA 250

Query: 172 EPV--------------------EKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTC 211
            P                          T +C  CHK +  R L   A+   YH + F C
Sbjct: 251 TPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLV--ALGHAYHPEEFVC 308

Query: 212 RTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCV 270
             C + L    F+++ G   C PCY       C KC + +   I+ AL   +H  CFTC 
Sbjct: 309 SQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCA 368

Query: 271 TCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHE 330
            C   I + +F +  +   YC  D+ + F   C  C+  I   D  D F +E +G ++H+
Sbjct: 369 ACKTPIRNRAFYM-EEGVPYCERDYEKMFGTKCHGCDFKI---DAGDRF-LEALGFSWHD 423

Query: 331 NCYRCEDCRILL 342
            C+ C  C+I L
Sbjct: 424 TCFVCAICQINL 435



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 18/51 (35%), Positives = 27/51 (52%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           C  C   +   +  +EA+   +H  CF C  C+  L G++FY K  RPLC+
Sbjct: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 10/72 (13%)

Query: 301 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 360
           PVC  C   I  R       +  +G  +H   + C  C  +L     + G +     +FC
Sbjct: 280 PVCHQCHKVIRGR------YLVALGHAYHPEEFVCSQCGKVLE----EGGFFEEKGAIFC 329

Query: 361 KPCHVKRSAAGC 372
            PC+  R A  C
Sbjct: 330 PPCYDVRYAPSC 341


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 8/164 (4%)

Query: 180 TDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDT 239
           T +C  CHK +  R L   A+   YH + F C  C + L    F+++ G   C PCY   
Sbjct: 245 TPVCHQCHKVIRGRYLV--ALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 302

Query: 240 LE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRK 298
               C KC + +   I+ AL   +H  CFTC  C   I + +F +  +   YC  D+ + 
Sbjct: 303 YAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYM-EEGVPYCERDYEKM 361

Query: 299 FAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILL 342
           F   C  C+  I   D  D F +E +G ++H+ C+ C  C+I L
Sbjct: 362 FGTKCHGCDFKI---DAGDRF-LEALGFSWHDTCFVCAICQINL 401



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%)

Query: 169 PPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDG 228
           PP   V    S   CA C K ++     + A+K  +H  CFTC  C+  +  ++FY ++G
Sbjct: 296 PPCYDVRYAPS---CAKCKKKITGE--IMHALKMTWHVHCFTCAACKTPIRNRAFYMEEG 350

Query: 229 RPLCEPCYQDTL-ERCGKCGEVV--RDHIIRALGQAFHPSCFTCVTC 272
            P CE  Y+     +C  C   +   D  + ALG ++H +CF C  C
Sbjct: 351 VPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 397



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 18/51 (35%), Positives = 27/51 (52%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
           C  C   +   +  +EA+   +H  CF C  C+  L G++FY K  RPLC+
Sbjct: 366 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 10/72 (13%)

Query: 301 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 360
           PVC  C   I  R       +  +G  +H   + C  C  +L     + G +     +FC
Sbjct: 246 PVCHQCHKVIRGR------YLVALGHAYHPEEFVCSQCGKVLE----EGGFFEEKGAIFC 295

Query: 361 KPCHVKRSAAGC 372
            PC+  R A  C
Sbjct: 296 PPCYDVRYAPSC 307


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C K +   +  VE     +H  CFTC  C++ +   SF+ K     C  C++    +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160

Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
            C KC + +    I    Q +H  CF CVTC++ +  + F    +++ YC+D +    A 
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
            C+ C+NPI    GK +  +   G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 158

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 359
           A  C  C N  I   G     I    + +H +C+ C  C    S +   Q    + +  +
Sbjct: 159 AKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAVEDQYY 208

Query: 360 CKPCH---VKRSAAGC 372
           C  C+   V +  AGC
Sbjct: 209 CVDCYKNFVAKKCAGC 224



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 262
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61

Query: 263 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 322
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 62  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116

Query: 323 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C+K ++   +  +   + +HA CF C TC ++LAGQ F   + +  C  CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 242 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 293
           +C  C   +        ++   GQ++H  CF C  C+  + ++ F    Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C K +   +  VE     +H  CFTC  C++ +   SF+ K     C  C++    +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160

Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
            C KC + +    I    Q +H  CF CVTC++ +  + F    +++ YC+D +    A 
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
            C+ C+NPI    GK +  +   G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 158

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 359
           A  C  C N  I   G     I    + +H +C+ C  C    S +   Q    + +  +
Sbjct: 159 AKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAVEDQYY 208

Query: 360 CKPCH---VKRSAAGC 372
           C  C+   V +  AGC
Sbjct: 209 CVDCYKNFVAKKCAGC 224



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 262
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61

Query: 263 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 322
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 62  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116

Query: 323 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C+K ++   +  +   + +HA CF C TC ++LAGQ F   + +  C  CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 242 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 293
           +C  C   +        ++   GQ++H  CF C  C+  + ++ F    Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C K +   +  VE     +H  CFTC  C++ +   SF+ K     C  C++    +
Sbjct: 130 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 189

Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
            C KC + +    I    Q +H  CF CVTC++ +  + F    +++ YC+D +    A 
Sbjct: 190 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 248

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
            C+ C+NPI    GK +  +   G+++H+ C+ C+ C + L+
Sbjct: 249 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 289



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 69  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 128

Query: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 129 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 187

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 359
           A  C  C N  I   G     I    + +H +C+ C  C    S +   Q    + +  +
Sbjct: 188 AKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAVEDQYY 237

Query: 360 CKPCH---VKRSAAGC 372
           C  C+   V +  AGC
Sbjct: 238 CVDCYKNFVAKKCAGC 253



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 262
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 31  AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 90

Query: 263 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 322
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 91  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 145

Query: 323 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 146 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 191



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C+K ++   +  +   + +HA CF C TC ++LAGQ F   + +  C  CY++ + +
Sbjct: 191 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 248

Query: 242 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 293
           +C  C   +        ++   GQ++H  CF C  C+  + ++ F    Q +VYC D
Sbjct: 249 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 304


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C K +   +  VE     +H  CFTC  C++ +   SF+ K     C  C++    +
Sbjct: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176

Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
            C KC + +    I    Q +H  CF CVTC++ +  + F    +++ YC+D +    A 
Sbjct: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 235

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
            C+ C+NPI    GK +  +   G+++H+ C+ C+ C + L+
Sbjct: 236 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 276



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 56  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115

Query: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 174

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 359
           A  C  C N  I   G     I    + +H +C+ C  C    S +   Q    + +  +
Sbjct: 175 AKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAVEDQYY 224

Query: 360 CKPCH---VKRSAAGC 372
           C  C+   V +  AGC
Sbjct: 225 CVDCYKNFVAKKCAGC 240



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 17/189 (8%)

Query: 187 HKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGK 245
           H+   P    V  M     A+ F C  CR  L G+ + QKDG   C  C+       C +
Sbjct: 4   HRHSGPSSYKVGTM-----AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVE 58

Query: 246 CGEVV--RDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVC 303
           C + +      +    + +H +CF C  C   + +E+F +   N++ C     R+ +P C
Sbjct: 59  CRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKC 117

Query: 304 SICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPC 363
             C   I+  D      +E  G  +H++C+ C +C+ ++         +P     +C  C
Sbjct: 118 KGCFKAIVAGDQ----NVEYKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTC 169

Query: 364 HVKRSAAGC 372
           H  + A  C
Sbjct: 170 HETKFAKHC 178



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C+K ++   +  +   + +HA CF C TC ++LAGQ F   + +  C  CY++ + +
Sbjct: 178 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235

Query: 242 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 293
           +C  C   +        ++   GQ++H  CF C  C+  + ++ F    Q +VYC D
Sbjct: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 291


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
           C  C K +   +  VE     +H  CFTC  C++ +   SF+ K     C  C++    +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160

Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
            C KC + +    I    Q +H  CF CVTC++ +  + F    +++ YC+D +    A 
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 343
            C+ C+NPI    GK +  +   G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-YQDTLE 241
           C  C K +      V    R +H  CF C  C   LA ++F  KD + LC  C  ++   
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 242 RCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C  C +  V  D  +   G  +H  CFTC  C + IG  SF      + YC+     KF
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTCHETKF 158

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 359
           A  C  C N  I   G     I    + +H +C+ C  C    S +   Q    + +  +
Sbjct: 159 AKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAVEDQYY 208

Query: 360 CKPCH---VKRSAAGC 372
           C  C+   V +  AGC
Sbjct: 209 CVDCYKNFVAKKCAGC 224



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 206 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 262
           A+ F C  CR  L G+ + QKDG   C  C+       C +C + +      +    + +
Sbjct: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61

Query: 263 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 322
           H +CF C  C   + +E+F +   N++ C     R+ +P C  C   I+  D      +E
Sbjct: 62  HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116

Query: 323 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
             G  +H++C+ C +C+ ++         +P     +C  CH  + A  C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C+K ++   +  +   + +HA CF C TC ++LAGQ F   + +  C  CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 242 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 293
           +C  C   +        ++   GQ++H  CF C  C+  + ++ F    Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 8/182 (4%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQ-DTLE 241
           C  C KT+ P    +E     +H  CF C  C++ +  +SF  KD +  C PCY+     
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           +C +C + +    +    Q +H  CF C  C + +  + F     +  YCL+ F   +A 
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFT-ARDDFAYCLNCFCDLYAK 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 361
            C+ C NPI    G      E   R +H +C+ C+ C + L      +G     + + C 
Sbjct: 220 KCAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSL----VGRGFLTERDDILCP 273

Query: 362 PC 363
            C
Sbjct: 274 DC 275



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 46/169 (27%), Positives = 80/169 (47%), Gaps = 16/169 (9%)

Query: 209 FTCRTCRRQLAGQSFYQKDGRPLCEPCYQ----DTLERCGK-CGEVVRDHIIRALGQAFH 263
           F C  C   L G+ +  ++  P C  C++    +T E CGK  G   +D  +    + +H
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKD--LSYKDRHWH 62

Query: 264 PSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIEC 323
            +CF C  C   + D+ FA   ++++ C D +  +++  C  C+  I+P       K+E 
Sbjct: 63  EACFHCSQCRNSLVDKPFA-AKEDQLLCTDCYSNEYSSKCQECKKTIMP----GTRKMEY 117

Query: 324 MGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
            G ++HE C+ C  C+  +      +   P +N  FC PC+ K+ A  C
Sbjct: 118 KGSSWHETCFICHRCQQPIGT----KSFIPKDNQNFCVPCYEKQHAMQC 162



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 21/198 (10%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C K +      +    R +H  CF C  CR  L  + F  K+ + LC  CY +    
Sbjct: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99

Query: 242 RCGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C +C + +      +   G ++H +CF C  C + IG +SF +   N+ +C+  + ++ 
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSF-IPKDNQNFCVPCYEKQH 158

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVE---PTDQGCYPLN- 355
           A  C  C+ PI          +    + +H+ C+ C  CR  LS +     D   Y LN 
Sbjct: 159 AMQCVQCKKPITTGG------VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNC 212

Query: 356 -NHLFCKPCHVKRSAAGC 372
              L+ K C      AGC
Sbjct: 213 FCDLYAKKC------AGC 224



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 183 CAFCHKTVS----PRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD 238
           CA C   +S     + ++ E  +RQ+H  CF C+ C   L G+ F  +    LC  C +D
Sbjct: 221 CAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 8/182 (4%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQ-DTLE 241
           C  C KT+ P    +E     +H  CF C  C++ +  +SF  KD +  C PCY+     
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
           +C +C + +    +    Q +H  CF C  C + +  + F     +  YCL+ F   +A 
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFT-ARDDFAYCLNCFCDLYAK 219

Query: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 361
            C+ C NPI    G      E   R +H +C+ C+ C + L      +G     + + C 
Sbjct: 220 KCAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSL----VGRGFLTERDDILCP 273

Query: 362 PC 363
            C
Sbjct: 274 DC 275



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 46/169 (27%), Positives = 80/169 (47%), Gaps = 16/169 (9%)

Query: 209 FTCRTCRRQLAGQSFYQKDGRPLCEPCYQ----DTLERCGK-CGEVVRDHIIRALGQAFH 263
           F C  C   L G+ +  ++  P C  C++    +T E CGK  G   +D  +    + +H
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKD--LSYKDRHWH 62

Query: 264 PSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIEC 323
            +CF C  C   + D+ FA   ++++ C D +  +++  C  C+  I+P       K+E 
Sbjct: 63  EACFHCSQCRNSLVDKPFA-AKEDQLLCTDCYSNEYSSKCQECKKTIMP----GTRKMEY 117

Query: 324 MGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 372
            G ++HE C+ C  C+  +      +   P +N  FC PC+ K+ A  C
Sbjct: 118 KGSSWHETCFICHRCQQPIGT----KSFIPKDNQNFCVPCYEKQHAMQC 162



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 21/198 (10%)

Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
           C  C K +      +    R +H  CF C  CR  L  + F  K+ + LC  CY +    
Sbjct: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99

Query: 242 RCGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
           +C +C + +      +   G ++H +CF C  C + IG +SF +   N+ +C+  + ++ 
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSF-IPKDNQNFCVPCYEKQH 158

Query: 300 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVE---PTDQGCYPLN- 355
           A  C  C+ PI          +    + +H+ C+ C  CR  LS +     D   Y LN 
Sbjct: 159 AMQCVQCKKPITTGG------VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNC 212

Query: 356 -NHLFCKPCHVKRSAAGC 372
              L+ K C      AGC
Sbjct: 213 FCDLYAKKC------AGC 224



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 183 CAFCHKTVS----PRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD 238
           CA C   +S     + ++ E  +RQ+H  CF C+ C   L G+ F  +    LC  C +D
Sbjct: 221 CAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,658,557
Number of Sequences: 37866
Number of extensions: 1785754
Number of successful extensions: 35726
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 649
Number of HSP's successfully gapped in prelim test: 1476
Number of HSP's that attempted gapping in prelim test: 12928
Number of HSP's gapped (non-prelim): 10918
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.