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Search of human proteins with 66346695
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346695 fibrillin 2 precursor [Homo sapiens]
(2912 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346695 fibrillin 2 precursor [Homo sapiens] 6509 0.0
gi|24430141 fibrillin 1 precursor [Homo sapiens] 4586 0.0
gi|56237021 fibrillin 3 precursor [Homo sapiens] 4452 0.0
gi|110347437 latent transforming growth factor beta binding prot... 524 e-148
gi|110347412 latent transforming growth factor beta binding prot... 524 e-148
gi|110347431 latent transforming growth factor beta binding prot... 524 e-148
gi|4557733 latent transforming growth factor beta binding protei... 494 e-139
gi|24041035 notch 2 preproprotein [Homo sapiens] 489 e-137
gi|148833508 notch1 preproprotein [Homo sapiens] 473 e-133
gi|46249414 latent transforming growth factor beta binding prote... 472 e-132
gi|46249412 latent transforming growth factor beta binding prote... 472 e-132
gi|134244285 Notch homolog 3 [Homo sapiens] 461 e-129
gi|18497288 latent transforming growth factor beta binding prote... 441 e-123
gi|194328809 latent transforming growth factor beta binding prot... 432 e-120
gi|55770876 notch4 preproprotein [Homo sapiens] 315 4e-85
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 304 7e-82
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 276 2e-73
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 276 3e-73
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 276 3e-73
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 266 2e-70
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 254 1e-66
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 246 2e-64
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 242 4e-63
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 235 4e-61
gi|34734066 fibulin 1 isoform D [Homo sapiens] 234 1e-60
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 233 2e-60
gi|118572606 hemicentin 1 [Homo sapiens] 232 4e-60
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 231 8e-60
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 231 8e-60
gi|10190748 CEGP1 protein [Homo sapiens] 228 7e-59
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 6509 bits (16887), Expect = 0.0
Identities = 2912/2912 (100%), Positives = 2912/2912 (100%)
Query: 1 MGRRRRLCLQLYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLA 60
MGRRRRLCLQLYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLA
Sbjct: 1 MGRRRRLCLQLYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLA 60
Query: 61 PEYREEGAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCG 120
PEYREEGAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCG
Sbjct: 61 PEYREEGAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCG 120
Query: 121 DGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVC 180
DGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVC
Sbjct: 121 DGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVC 180
Query: 181 ENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 240
ENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC
Sbjct: 181 ENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 240
Query: 241 ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE
Sbjct: 241 ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
Query: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID
Sbjct: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Query: 361 QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDG 420
QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDG
Sbjct: 361 QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDG 420
Query: 421 LPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGG 480
LPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGG
Sbjct: 421 LPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGG 480
Query: 481 QGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECT 540
QGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECT
Sbjct: 481 QGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECT 540
Query: 541 SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQC 600
SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQC
Sbjct: 541 SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQC 600
Query: 601 ICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVD 660
ICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVD
Sbjct: 601 ICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVD 660
Query: 661 ECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFP 720
ECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFP
Sbjct: 661 ECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFP 720
Query: 721 GAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA 780
GAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA
Sbjct: 721 GAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA 780
Query: 781 NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPG 840
NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPG
Sbjct: 781 NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPG 840
Query: 841 YVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWL 900
YVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWL
Sbjct: 841 YVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWL 900
Query: 901 NIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECE 960
NIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECE
Sbjct: 901 NIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECE 960
Query: 961 VFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKF 1020
VFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKF
Sbjct: 961 VFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKF 1020
Query: 1021 RMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAF 1080
RMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAF
Sbjct: 1021 RMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAF 1080
Query: 1081 PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFEC 1140
PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFEC
Sbjct: 1081 PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFEC 1140
Query: 1141 ECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD 1200
ECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD
Sbjct: 1141 ECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD 1200
Query: 1201 INECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNS 1260
INECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNS
Sbjct: 1201 INECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNS 1260
Query: 1261 EGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM 1320
EGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM
Sbjct: 1261 EGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM 1320
Query: 1321 KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDM 1380
KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDM
Sbjct: 1321 KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDM 1380
Query: 1381 HASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF 1440
HASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF
Sbjct: 1381 HASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF 1440
Query: 1441 TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI 1500
TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI
Sbjct: 1441 TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI 1500
Query: 1501 CVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPP 1560
CVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPP
Sbjct: 1501 CVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPP 1560
Query: 1561 DFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET 1620
DFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET
Sbjct: 1561 DFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET 1620
Query: 1621 CPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQG 1680
CPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQG
Sbjct: 1621 CPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQG 1680
Query: 1681 YYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFC 1740
YYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFC
Sbjct: 1681 YYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFC 1740
Query: 1741 YRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFD 1800
YRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFD
Sbjct: 1741 YRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFD 1800
Query: 1801 IHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNL 1860
IHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNL
Sbjct: 1801 IHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNL 1860
Query: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH 1920
CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH
Sbjct: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH 1920
Query: 1921 NGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSF 1980
NGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSF
Sbjct: 1921 NGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSF 1980
Query: 1981 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR
Sbjct: 1981 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
Query: 2041 CICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
CICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR
Sbjct: 2041 CICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
Query: 2101 QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2160
QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG
Sbjct: 2101 QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2160
Query: 2161 TVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG 2220
TVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG
Sbjct: 2161 TVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG 2220
Query: 2221 NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCP 2280
NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCP
Sbjct: 2221 NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCP 2280
Query: 2281 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 2340
IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN
Sbjct: 2281 IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDEN 2340
Query: 2341 ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS
Sbjct: 2341 ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
Query: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC 2460
SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC
Sbjct: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC 2460
Query: 2461 TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRG 2520
TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRG
Sbjct: 2461 TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRG 2520
Query: 2521 YVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPS 2580
YVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPS
Sbjct: 2521 YVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPS 2580
Query: 2581 LCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCP 2640
LCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCP
Sbjct: 2581 LCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCP 2640
Query: 2641 QGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECS 2700
QGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECS
Sbjct: 2641 QGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECS 2700
Query: 2701 SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE 2760
SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE
Sbjct: 2701 SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE 2760
Query: 2761 ACYECKINGYSKKDSRQKRSIHEPDPTAVEQISLESVDMDSPVNMKFNLSHLGSKEHILE 2820
ACYECKINGYSKKDSRQKRSIHEPDPTAVEQISLESVDMDSPVNMKFNLSHLGSKEHILE
Sbjct: 2761 ACYECKINGYSKKDSRQKRSIHEPDPTAVEQISLESVDMDSPVNMKFNLSHLGSKEHILE 2820
Query: 2821 LRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMPGTYTLEITSIPLYKK 2880
LRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMPGTYTLEITSIPLYKK
Sbjct: 2821 LRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMPGTYTLEITSIPLYKK 2880
Query: 2881 KELKKLEESNEDDYLLGELGEALRMRLQIQLY 2912
KELKKLEESNEDDYLLGELGEALRMRLQIQLY
Sbjct: 2881 KELKKLEESNEDDYLLGELGEALRMRLQIQLY 2912
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 4586 bits (11896), Expect = 0.0
Identities = 1972/2867 (68%), Positives = 2342/2867 (81%), Gaps = 59/2867 (2%)
Query: 71 ASRVRRRGQ--QDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPN 128
ASR +RRG D L+GPNVCGSR+++YCCPGWKTLPGGNQCIVPICR+SCGDGFCSRPN
Sbjct: 39 ASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPN 98
Query: 129 MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGG 188
MCTC SGQI+ +CGS+SIQ C++RCMNGG+C+DDHC CQKGYIGT+CGQPVCE+GC NGG
Sbjct: 99 MCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGG 158
Query: 189 RCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG 248
RC+ PNRCAC YGFTGPQCERDYRTGPCFT ++NQMCQGQL+GIVCTKTLCCAT+GRAWG
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG 218
Query: 249 HPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHK 308
HPCEMCPAQP PCRRGFIPNIRTGACQDVDECQAIPG+CQGGNCINTVGSFEC+CPAGHK
Sbjct: 219 HPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 278
Query: 309 QSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFS 368
+E +QKCEDIDECS IPGICE GEC+NTV SYFC CP G+ TS DG+RCID R G C++
Sbjct: 279 LNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYT 338
Query: 369 GLVNGRCAQELPGRMTKMQCCCEPGRCW--GIGTIPEACPVRGSEEYRRLCMDGLPMGGI 426
L NGRC+ +LP +TKMQCCC+ GRCW G+ PE CP+R +E++ +LC +PM I
Sbjct: 339 ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLC--SVPMV-I 395
Query: 427 PGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIP--IPGGNGFSPG----VGGAGVG--- 477
PG RP Y P G IP +P GF PG V V
Sbjct: 396 PG----RPE---------------YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLY 436
Query: 478 AGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVD 537
+ P + + + D C+ LC NGRCIPT S RCECN G++ D G+CIDVD
Sbjct: 437 PSREPPRVLPVNVT----DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVD 492
Query: 538 ECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGS 597
EC NPC G+C+N GSY C+C AG+Q T T+ C DIDEC+QNG +C NGRC+NTDGS
Sbjct: 493 ECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGS 552
Query: 598 FQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT 657
F C+CNAGF +T DGKNC D DEC+ NMCLNGMCINEDGSFKCICKPGF LA +GRYC
Sbjct: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612
Query: 658 DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVR 717
D++EC+TPGICMNG C+N++GS+RC+C PGLAVG+DGRVCVDTHMRSTCYGG K+G C++
Sbjct: 613 DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIK 672
Query: 718 PFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPD 777
P GAVTKSECCCA+ +Y FGEPCQPCPA+NSAE+ LCSSG G+T G DINECALDPD
Sbjct: 673 PLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPD 732
Query: 778 ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTC 837
IC NGICENLRG+Y+C CNSGYE D++G+NC+DI+EC++N LLCDNG CRNTPGS+ CTC
Sbjct: 733 ICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTC 792
Query: 838 PPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT 897
P G++++ + +TCEDI+ECES+PC+NG C+N+ GSF CECS S L T ICI+++KGT
Sbjct: 793 PKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGT 852
Query: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVN 957
CW + D RCE+NINGATLKS+CC++LGAAWGSPC C++D C +G +RIKG CED++
Sbjct: 853 CWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDID 912
Query: 958 ECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVP 1017
ECEVFPGVC NG CVN++GSF C+CP G+TLD TGR+CLDIR+E C+L+++++EC P+
Sbjct: 913 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIA 972
Query: 1018 GKFRMDACCCAVGAAWGTE-CEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 1076
G+ RMDACCC+VGAAWGTE CEECP T EYE LCPRG GFA + ++ G+PF+KDINE
Sbjct: 973 GRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK-EITNGKPFFKDINE 1031
Query: 1077 CKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPG 1136
CK P +CT+GKCRNTIGSFKCRC+SGFALD EERNCTDIDECRISPDLCG G CVNTPG
Sbjct: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPG 1091
Query: 1137 SFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRE 1196
FEC+C EGYESGFMMMKNCMDIDEC+R+PLLCRGG C NTEGS++C+CP GH+LSP+
Sbjct: 1092 DFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNIS 1151
Query: 1197 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
C+DINEC LS +LC NG+CVN+IG YQC+CNPGY +TPDR C DIDEC IMNGGC+T
Sbjct: 1152 ACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF 1211
Query: 1257 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 1316
CTNSEGSYECSC G+ALMPD RSC DIDECE+NP+ICDGGQCTNIPGEYRCLCYDGFMA
Sbjct: 1212 CTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271
Query: 1317 SMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAH 1376
S DMKTC+DVNECDLN NIC+ G CENTKGSFICHC +GYS KKG TGCTD++ECEIGAH
Sbjct: 1272 SEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAH 1331
Query: 1377 NCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCAC 1436
NC HA C N GSFKCSC GWIG+GIKC DLDECSNGTH CS +A C NT GSYRC C
Sbjct: 1332 NCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1391
Query: 1437 SEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS 1496
EG+TGDGFTC+D+DEC+EN+NLC NGQCLN PG YRCEC+MGF P++D ++C+DIDECS
Sbjct: 1392 KEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS 1451
Query: 1497 FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYEC 1556
NICVFGTC+NLPG+F C C+ GYELDR+GGNCTD++EC DP C++G CVNTPG Y C
Sbjct: 1452 LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC 1511
Query: 1557 NCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGD-GSLSCNTEIGVGVSRSSCCCSLGKAWG 1615
+CPPDF+LNPT VGCVD R GNCYL PRGD G +C+ EIGVGVS++SCCCSLGKAWG
Sbjct: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG 1571
Query: 1616 NPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQC 1675
PCE CP VN++EY LCPGGEGFRPNPIT+ILEDIDECQELPGLCQGG CINTFGSFQC
Sbjct: 1572 TPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQC 1631
Query: 1676 ECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDM 1735
CP GYYL+EDTR+C+D++EC PG+CGPGTCYNT+GNYTCICPP+YMQVNGG+NCMDM
Sbjct: 1632 RCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
Query: 1736 RKSFCYRSY--NGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN 1793
R+S CYR+Y + TC+ EL FN+TK+MCCC+YN+G+AWNKPCE CP P T +F T+CG+
Sbjct: 1691 RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGS 1750
Query: 1794 I-PGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDID 1852
PGF DI+TG VDIDEC+EIPG+C NGVCIN +GSFRCECP GF YND LLVCEDID
Sbjct: 1751 QRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDID 1810
Query: 1853 ECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
EC NG +CQRNA+CIN+ GSYRC+C G++ + G C DRNEC EIPN+CSHG C+D
Sbjct: 1811 ECQNGP-VCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV 1869
Query: 1913 GSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCL 1972
GS+ C+CH GFK + DQTMC+D++ECER CGNGTC+NT+GS+NC C GF L+HNNDC+
Sbjct: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI 1929
Query: 1973 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTC 2032
D+DEC+S G +CRNG+C N +GSF+C CNEGYE+ PDG+ C+D NEC+ P C+PGTC
Sbjct: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989
Query: 2033 QNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDN 2092
QNL+GS+RCICPPGY +++E C DI+EC E+P IC G+C+NT G F+CLCP GF LS +
Sbjct: 1990 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSS 2049
Query: 2093 GRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQ 2152
GRRC D R S+C+ FE GKCS PK+ N +K +CCC+ + GEGWGDPCELCP + + AF+
Sbjct: 2050 GRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCA-LKGEGWGDPCELCPTEPDEAFR 2108
Query: 2153 DLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 2212
+CPYG G + D+ D++EC E P +C +GQCINTDGS+RCECP GY L G CV
Sbjct: 2109 QICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYIL--AGNECV 2165
Query: 2213 DTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF 2272
DTDECS+GNPCGNGTC NVIG FEC C EGFEPGPMM CEDINECAQNPLLCAFRC+NT+
Sbjct: 2166 DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTY 2225
Query: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
GSYEC CP+GY LRED++MCKD DEC EG HDC + M CKNLIGT+MCIC PG RRPD
Sbjct: 2226 GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPD 2285
Query: 2333 GEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQ 2392
GEGCVDENEC+TKPGICENGRC+N GSY CECN+GF +S + ECLDNR+G CF EVLQ
Sbjct: 2286 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQ 2345
Query: 2393 TICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDE 2452
+CQ+ SS+RN VTKSECCCDGGRGWG CE+CP GT +KK+CPHG G+ T+G DIDE
Sbjct: 2346 NMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDE 2405
Query: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGS 2512
CKV+ ++C NG+C+N GS+ C CK GYT DI+GTSC+DL+EC+Q+PKPCN+ICKNTEGS
Sbjct: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGS 2465
Query: 2513 YQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDN 2572
YQCSCP+GY+LQEDG++CKDLDEC TKQHNCQFLCVNT+GGFTCKCPPGFTQHHT+CIDN
Sbjct: 2466 YQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN 2525
Query: 2573 NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNIL 2632
NEC S +LCG+KGICQNTPGSF+CECQRGFSLD TG +CEDVDEC+GNHRCQHGCQNI+
Sbjct: 2526 NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNII 2585
Query: 2633 GGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSA 2692
GGYRC CPQGY+QHYQWNQCVDENEC + + CG ASC+NTLGSYKC CP+GF ++QFS
Sbjct: 2586 GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
Query: 2693 CHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVD 2752
C D+NEC S++ PC+YGCSNTEGGYLCGCPPGY+R+GQGHCVSGMG +G +
Sbjct: 2646 CQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEM 2705
Query: 2753 EENALSPEACYECKINGYSKKDSRQKRSIHEPDPTAVE-------QISLESVDMDSPVNM 2805
++N+LSPEACYECKINGY K+ R++RS +E D + +E +SL S D++
Sbjct: 2706 DDNSLSPEACYECKINGYPKR-GRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIF 2764
Query: 2806 KFNLSHLGSKEHILELRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMP 2865
FN+SH+ +K ILEL PA+ L NH RY+I GN+D F+I+Q+ G+SYLH KKK +
Sbjct: 2765 AFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVA 2824
Query: 2866 GTYTLEITSIPLYKKKELKKLEESNEDDYLLGELGEALRMRLQIQLY 2912
GTY+L+I+S PLYKKKEL +LE+ + DYL GELG+ L+M++Q+ L+
Sbjct: 2825 GTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2871
Score = 1061 bits (2744), Expect = 0.0
Identities = 746/2395 (31%), Positives = 1040/2395 (43%), Gaps = 475/2395 (19%)
Query: 32 PPPPKPPRPQPP---------PQQVRSATAGSEGGFLAPEYREEGAAVASRVR-----RR 77
PP P+ P P+PP P +V ++ L + G + + +
Sbjct: 420 PPGPQIPVPRPPVEYLYPSREPPRVLPVNV-TDYCQLVRYLCQNGRCIPTPGSCRCECNK 478
Query: 78 GQQDVLRGPNV--------------CGSRFHSYCC---PGWKTLPGGNQC--IVPICRNS 118
G Q LRG + C + SY C G+++ +C I +N
Sbjct: 479 GFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNG 538
Query: 119 --CGDGFCSRPN---MCTCSSGQISSTCGS--KSIQQCSVR--CMNGGTCADD---HCQC 166
C +G C + C C++G + G + + +CS+R C+NG +D C C
Sbjct: 539 RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCIC 598
Query: 167 QKGY----IGTYCGQ-PVCEN-GCQNGGRCI---GPNRCAC----VYGFTGPQCERDYRT 213
+ G+ G YC CE G GRC+ G RC C G G C +
Sbjct: 599 KPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMR 658
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQP-----CRRGFIPN 268
C+ C L G V CCA+ A+G PC+ CPAQ C G P
Sbjct: 659 STCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--PG 716
Query: 269 IRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGI 328
+ T A D++EC P IC G C N G+++C C +G++ T + C DI+EC + +
Sbjct: 717 M-TSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLL 775
Query: 329 CETGECSNTVGSYFCVCPRGYVTSTD---------------------------------- 354
C+ G+C NT GS+ C CP+G++ D
Sbjct: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSE 835
Query: 355 ------GSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIG-TIPEACPV 407
+ CI+ G C+ +++GRC + G K QCC G WG T+ + P+
Sbjct: 836 STLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPI 895
Query: 408 RGSEEYRRL----CMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
G + Y R+ C D PG NG G+ P
Sbjct: 896 CG-KGYSRIKGTQCEDIDECEVFPGVC---------------KNGLCVNTRGSFKCQCPS 939
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDIC--KHHANLCLNGRCIPTVSSYR--- 518
G TG L+ ++ C ++ C +P +R
Sbjct: 940 GMTLD----------------ATGRICLDIRLETCFLRYEDEEC----TLPIAGRHRMDA 979
Query: 519 CECNMGYKQDANGDCIDVDECTSNPCTNGD-----CVNTPGSYYCKCHAGFQRTPTKQAC 573
C C++ G +EC P N C PG A + T K
Sbjct: 980 CCCSV-------GAAWGTEECEECPMRNTPEYEELCPRGPG------FATKEITNGKPFF 1026
Query: 574 IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDEC-TTTNMCLNGMC 632
DI+EC LC +G+C NT GSF+C C++GF L ++ +NC D DEC + ++C G C
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1086
Query: 633 INEDGSFKCIC----KPGFVLAPNGRYCTDVDECQ-TPGICMNGHCINSEGSFRCDCPPG 687
+N G F+C C + GF++ N C D+DECQ P +C G C N+EGS+RC+CPPG
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKN---CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 1143
Query: 688 LAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCC-----ANPDYGFGEPCQ 742
+ + C+D + G CV + K +C C + PD F
Sbjct: 1144 HQLSPNISACIDINECELSAHLCPNGRCV----NLIGKYQCACNPGYHSTPDRLFCVDID 1199
Query: 743 PCPAKN----------SAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRG 789
C N + C G + D R DI+EC +P+IC G C N+ G
Sbjct: 1200 ECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPG 1259
Query: 790 SYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETET 849
YRC C G+ + C+D++EC +N +C +G C NT GS+ C C GY +
Sbjct: 1260 EYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTG 1319
Query: 850 CEDINECE---SNPCVNGACRNNLGSFNCECSPG-------------------------- 880
C DINECE N + C N GSF C CSPG
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHAD 1379
Query: 881 --SKLSSTGLICIDSLKGTCWLNIQDSRCEVNI----NGATLKS----ECCATLG---AA 927
+ + S +C + G + C N+ NG L + C +G +A
Sbjct: 1380 CKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSA 1439
Query: 928 WGSPCE---RCELDTACP-------RGLARIK----------GVTCEDVNECEVFPGVCP 967
G CE C L C GL R + G C DVNEC + P C
Sbjct: 1440 DGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCI 1498
Query: 968 NGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYL----KWDEDE--CIHPVPGKFR 1021
+G CVN+ GS+ C+CP L+ T C+D R CYL + D + C + +
Sbjct: 1499 SGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVS 1558
Query: 1022 MDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFP 1081
+CCC++G AWGT CE CP T EY+ LCP G GF R + +T +DI+EC+ P
Sbjct: 1559 KASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGF--RPNPIT--VILEDIDECQELP 1614
Query: 1082 GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECE 1141
G+C GKC NT GSF+CRC +G+ L+ + R C D++EC +P +CG G C NT G++ C
Sbjct: 1615 GLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE-TPGICGPGTCYNTVGNYTCI 1673
Query: 1142 CFEGYESGFMMMKNCMDIDE--CERN----PLLCRGGTCVN-TEGSFQCDCPLGHELSPS 1194
C Y NCMD+ C RN C G N T+ C +G +
Sbjct: 1674 CPPDYMQ-VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 1732
Query: 1195 REDC----------------------------VDINECSLSDNLCRNGKCVNMIGTYQCS 1226
E C VDI+EC +C NG C+NM+G+++C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCE 1792
Query: 1227 CNPGYQATPDRQGCTDIDECMIMNGGC---DTQCTNSEGSYECSCSEGYALMPDGRSCAD 1283
C G+ C DIDEC NG + +C N+ GSY C C GY G+ C D
Sbjct: 1793 CPVGFFYNDKLLVCEDIDEC--QNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CND 1849
Query: 1284 IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECEN 1343
+EC+ P+IC GQC + G + CLC+ GF + D C+D+NEC+ ++ C G C N
Sbjct: 1850 RNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA--CGNGTCRN 1907
Query: 1344 TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--IG 1401
T GSF C C G+ + C DVDEC G N + C+N GSF+C C EG+
Sbjct: 1908 TIGSFNCRCNHGF-ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAP 1966
Query: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCE 1461
+G C+D++EC +C+ C N GSYRC C G++ C D+DEC E +C
Sbjct: 1967 DGRTCVDINECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICA 2025
Query: 1462 NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFH----CIC 1517
G C N G+++C C GF+ +S R CQD+ G C++ H C C
Sbjct: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
Query: 1518 -------DDGYELDRT--------------------GGNCTDIDECADPINCVNGLCVNT 1550
D EL T + D+DEC +P C +G C+NT
Sbjct: 2086 ALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2145
Query: 1551 PGRYECNCPPDFQLNPTGVGCVDN---RVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCC 1607
G Y C CP + L G CVD VGN P G+G +C IG C
Sbjct: 2146 DGSYRCECPFGYIL--AGNECVDTDECSVGN------PCGNG--TCKNVIG----GFECT 2191
Query: 1608 CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCI 1667
C EGF P P+ + EDI+EC + P LC C+
Sbjct: 2192 CE---------------------------EGFEPGPM-MTCEDINECAQNPLLC-AFRCV 2222
Query: 1668 NTFGSFQCECPQGYYLSEDTRICEDID--------------------------------- 1694
NT+GS++C+CP GY L ED R+C+D D
Sbjct: 2223 NTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQR 2282
Query: 1695 -----------ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRS 1743
EC PG+C G C NT G+YTC C + C+D R+ +C+
Sbjct: 2283 RPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTE 2342
Query: 1744 YNGTTCE----NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTF 1799
C+ N P VTK CCC + G+ W CE CP GT FK +C + GF
Sbjct: 2343 VLQNMCQIGSSNRNP--VTKSECCC--DGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMT 2398
Query: 1800 DIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDN 1859
+ DIDECK I +C NG C+N GS+ C C TG++ + C D++EC+
Sbjct: 2399 N-----GADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPK 2453
Query: 1860 LCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCI 1918
C N C N+ GSY+C C G+ L +G +C D +EC + C LCV+ G + C
Sbjct: 2454 PC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCK 2510
Query: 1919 CHNGFKASQDQTMCMDVDEC--ERHPCGN-GTCKNTVGSYNCLCYPGFELTH-NNDCLDI 1974
C GF +Q T C+D +EC + + CG+ G C+NT GS+ C C GF L + C D+
Sbjct: 2511 CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568
Query: 1975 DECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQN 2034
DEC C++G C N IG ++C C +GY C+D NEC++ C +C N
Sbjct: 2569 DECEG--NHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLS-AHICGGASCHN 2624
Query: 2035 LEGSFRCICPPG--YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 2087
GS++C+CP G YE S C DINEC C +G C+NT GG+ C CPPG+
Sbjct: 2625 TLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 4452 bits (11546), Expect = 0.0
Identities = 1901/2852 (66%), Positives = 2267/2852 (79%), Gaps = 90/2852 (3%)
Query: 68 AAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRP 127
AA RVRRRG +L+GPNVCGSRFH+YCCPGW+T PG +QC+VPICR +CG+GFCS+P
Sbjct: 39 AAGPGRVRRRGSPGILQGPNVCGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQP 98
Query: 128 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNG 187
N+CTC+ G ++ +CG CSV CMNGGTC C CQKGY GT CGQP+C+ GC NG
Sbjct: 99 NLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNG 158
Query: 188 GRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
GRCIGPNRCACVYGF GPQCERDYRTGPCF QV + CQ QLTG+VCTK LCCAT+GRAW
Sbjct: 159 GRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAW 218
Query: 248 GHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGH 307
G PCE+CPAQP PCRRGFIPNI TGA
Sbjct: 219 GLPCELCPAQPHPCRRGFIPNIHTGA---------------------------------- 244
Query: 308 KQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCF 367
C+D+DEC +PG+C+ G C N VGS+ C CP G+ S + C D R G CF
Sbjct: 245 --------CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Query: 368 SGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIP 427
S L GRCA +L G T+ QCCC+ GRCW G +PE CP RGS E+++LC LP+ +P
Sbjct: 297 SVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPL--LP 354
Query: 428 GSAGSRPG--GTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPII 485
G G PG G G NG P P G+ IP S G G + +G
Sbjct: 355 GHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIP-----SLGPGNSNIGTA------ 403
Query: 486 TGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT 545
LNQTIDIC+H NLCLNGRC+PT SSYRCECN+GY QD G+CIDVDECTS+PC
Sbjct: 404 ----TLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCH 459
Query: 546 NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAG 605
+GDCVN PG+Y+C+C+ GFQ TPT+QAC+D+DECI +G LC GRCVNT+GSFQC+CNAG
Sbjct: 460 HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAG 519
Query: 606 FELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTP 665
FEL+ DGKNCVDH+EC T+ MC+NG+C+NEDGSF C+CKPGF+LAP G YC D+DECQTP
Sbjct: 520 FELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTP 579
Query: 666 GICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTK 725
GIC+NGHC N+EGSFRC C GLAVG DGRVCVDTH+RSTCYG I+KG C RPFPG VTK
Sbjct: 580 GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTK 639
Query: 726 SECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICE 785
SECCCANPD+GFGEPCQ CPAK+SAEF LCSSG+GIT DGRDINECALDP++CANG+CE
Sbjct: 640 SECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCE 699
Query: 786 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 845
NLRGSYRC CN GYE ASG++C D+DEC +N LLCDNG C+N+PGSYSC+CPPG+ F
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 846 ETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDS 905
+TE C+D++EC S+PCV+G CRN GS+ C+C PGS+L +G C+DS KGTCWL IQ+S
Sbjct: 760 DTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQES 819
Query: 906 RCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGV 965
RCEVN+ GA+L+SECCATLGAAWGSPCERCE+D AC RG AR+ GVTC+DVNECE FPGV
Sbjct: 820 RCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGV 879
Query: 966 CPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDAC 1025
CPNGRCVN+ GSF CECPEGL LD +GR+C+D+R+E C+L+WDEDEC +PGK+RMD C
Sbjct: 880 CPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVC 939
Query: 1026 CCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCT 1085
CC++GA WG ECE CP P + E+ +LCPRG GFA+R D L+GRPFYKD+NECK FPG+CT
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRGLGFASR-DFLSGRPFYKDVNECKVFPGLCT 998
Query: 1086 YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEG 1145
+G CRNT+GSF C C GFALD +ERNCTDIDECRISPDLCG G CVNTPGSFECECF G
Sbjct: 999 HGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPG 1058
Query: 1146 YESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECS 1205
YESGFM+MKNCMD+DEC R+PLLCRGGTC NT+GS++C CP GHEL+ C DI+ECS
Sbjct: 1059 YESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS 1118
Query: 1206 LSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYE 1265
LSD LC +G+CVN+IG +QCSC+ G+Q+TPDRQGC DI+EC + NGGCD C N+EGSY
Sbjct: 1119 LSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYR 1178
Query: 1266 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1325
CSC +GY+LMPDGR+CAD+DECE NP +CD G CTN+PG +RCLCYDGFMA+ DM+TC+D
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 1326 VNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
V+ECDLN +IC+ G+CENTKGSF+CHCQLGY V+KG TGC+DVDECE+G HNCD HASCL
Sbjct: 1239 VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 1386 NIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGF 1445
NIPGSF C C GW+G+G +C DLDEC + H+CS C+N PGSYRC C +GF GDGF
Sbjct: 1299 NIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGF 1358
Query: 1446 TCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGT 1505
C D DECAEN++LC+NGQCLN PG YRCECEMGF P D R+CQD+DEC+ N+C FG+
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGS 1418
Query: 1506 CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLN 1565
C NLPGMF CIC+ GYELDR GGNCTDI+ECADP+NC+NG+C+NTPG Y C+CP DF+LN
Sbjct: 1419 CENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELN 1478
Query: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
P+GVGCVD R GNC+L+ RGD +SC+ EIGVGV+R+SCCCSLG+AWGNPCE CP N
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMAN 1538
Query: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
+TEY TLCPGGEGF+PN IT+ILEDIDECQELPGLCQGG+C+NTFGSFQCECP GY+LSE
Sbjct: 1539 TTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
TRICEDIDEC H G+CGPGTCYNTLGNYTC+CP EY+QVNGG+NCMDMRKS C+R YN
Sbjct: 1599 HTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYN 1658
Query: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN-IPGFTFDIHTG 1804
G TC+NEL FNVT++MCCC+YN+G+AWN+PCE CPTP + D++ +CGN PGF DIHTG
Sbjct: 1659 G-TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTG 1717
Query: 1805 KAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
K +DIDEC EIP ICANG+CINQIGSFRCECP GF+YN +LL CED+DEC + ++ CQ+N
Sbjct: 1718 KPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQN 1777
Query: 1865 ADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
ADCIN PGSYRC+C G+KLSP GACV RNEC EIPNVCSHG C+D +GSY C+CH GF+
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQ 1837
Query: 1925 ASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQV 1984
AS DQT+CMD+DEC+R PCGNGTCKN +GSYNCLC+PGF +THN DC+D DEC++ GQV
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV 1897
Query: 1985 CRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICP 2044
CR G C N GSF CLC +G+ELT DGKNC+DTNEC++L G+C PGTCQNLEGSFRCICP
Sbjct: 1898 CRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICP 1957
Query: 2045 PGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFC 2104
PG++V+S++CIDI+EC E+PN+CLFG+CTN+PG FQCLCPPGFVLSDNG RCFDTRQSFC
Sbjct: 1958 PGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFC 2017
Query: 2105 FTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPS 2164
FT FE GKCSVPKAFNTTK +CCCSK PGEGWGDPCELCP++ AFQ+LCP+GHG VP
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPG 2077
Query: 2165 LHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCG 2224
D+REDVNEC E+PG+C+NG C+NTDGSFRCECP GY+LD+TG+ CVDTDECS+G+PCG
Sbjct: 2078 PDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137
Query: 2225 NGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYA 2284
GTCTNVIG FEC C +GFEPG MM CEDI+EC+ NPLLCAFRC NT GSY CTCP GY
Sbjct: 2138 QGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 2285 LREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRP-DGEGCVDENECR 2343
LRED MC+D+DECA+G DC +RGM CKNLIGTF C+CPPGM P GEGC D+NEC
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 2344 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 2403
+P +C NGRCVN GS+RC+C+EGFQ S + TEC D RQG CFAEVLQT+C+ SSS
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 2404 LVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG 2463
VT++ECCC GGRGWG +CELCPLPGT+ Y+K+CPHG GYT +GRD+DEC+++ +LC +G
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHG 2377
Query: 2464 QCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVL 2523
+CIN++GSFRC C+ GYT D + T+C+D+DECSQ PKPC ++CKNT+GS+ CSCPRGY+L
Sbjct: 2378 ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLL 2437
Query: 2524 QEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCG 2583
+EDG+TCKDLDEC ++QHNCQFLCVNT+G FTC+CPPGFTQHH AC DN+EC +QP CG
Sbjct: 2438 EEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCG 2497
Query: 2584 AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGY 2643
A G C NTPGSF CEC +GF+L ++G CEDV+ECDG HRCQHGCQN LGGYRC CPQG+
Sbjct: 2498 AHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGF 2557
Query: 2644 IQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSS 2702
QH QW QCVDENEC+ +P CGSASC NTLG ++C CPSGF FDQ C +V+EC+
Sbjct: 2558 TQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGR 2617
Query: 2703 KNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEAC 2762
+ PC+Y C+NT GG+LCGCP GY+R GQGHCVSG+GF+ G DT D+E LS EAC
Sbjct: 2618 RGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGFSPGPQ---DTP-DKEELLSSEAC 2673
Query: 2763 YECKINGYSKKDSRQKRSIHEPDPTAVEQISLESVDMDSPVNMKFNLSHLGSKEHILELR 2822
YECKING S +D R +RS H Q++L ++D ++ + + NLSHLG E ILELR
Sbjct: 2674 YECKINGLSPRD-RPRRSAHRD-----HQVNLATLDSEALLTLGLNLSHLGRAERILELR 2727
Query: 2823 PAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMPGTYTLEITSI---PLYK 2879
PA++ L IRYVI +GN+ FR+H G+S L +++ PGTY LE+ S P
Sbjct: 2728 PALEGLEGRIRYVIVRGNEQGFFRMHHLRGVSSLQLGRRRPGPGTYRLEVVSHMAGPWGV 2787
Query: 2880 KKELKKLEESNEDDYLLGELGEALRMRLQIQL 2911
+ E + G G+ALR+++Q+QL
Sbjct: 2788 QPEGQP-----------GPWGQALRLKVQLQL 2808
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 524 bits (1350), Expect = e-148
Identities = 369/1186 (31%), Positives = 490/1186 (41%), Gaps = 172/1186 (14%)
Query: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFG-EPCQPCPAK--NSAEFH---GLCSSG 759
C+ ++ G C P PG T+ E CC +G CQ C + NS G C +G
Sbjct: 222 CFRELRGGECASPLPGLRTQ-EVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTG 280
Query: 760 VGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVN 817
V+G D++ECA C +G C N RG Y C C G+ D+S +C I + +++
Sbjct: 281 FE-RVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC--ISQHVIS 336
Query: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFN-CE 876
G C C+ P + C + + C + G C
Sbjct: 337 EA---KGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICP 393
Query: 877 CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE 936
PG S++ D T L + R ++ TL + + G E
Sbjct: 394 AGPGYHYSAS-----DLRYNTRPLGQEPPRVSLS-QPRTLPATSRPSAGFLPTHRLEPRP 447
Query: 937 LDTACPRG-----LARIKGVTCEDVNE-------CEVFPGVCPNGRCVNSKGSFHCECPE 984
PR L I T ++ E C+ P VC GRC++ + C C
Sbjct: 448 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 507
Query: 985 GLTLDGTGRVCLDIRMEQCYLKWDEDEC-----------IHPVPGKFRMDACCCAVGAAW 1033
G L G C+D+ DEC PG FR C C G
Sbjct: 508 GFRLSPQGTRCIDV-----------DECRRVPPPCAPGRCENSPGSFR---CVCGPGFRA 553
Query: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTI 1093
G EC D++EC P C G+C NT
Sbjct: 554 GPRAAEC-------------------------------LDVDECHRVPPPCDLGRCENTP 582
Query: 1094 GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMM 1153
GSF C C +G+ +C D+DEC SP LCG G C N PGSF C C G+
Sbjct: 583 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE 642
Query: 1154 KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN 1213
D+DEC + P C G C NT GSF C CP G C D++EC+ S C
Sbjct: 643 ----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY 698
Query: 1214 GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGY 1272
G+C N G++QC C G+Q C D+DEC +C NS GS++C +C G+
Sbjct: 699 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGH 758
Query: 1273 ALMPDGRSCADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMK-TCIDVNECD 1330
L GR C D+DEC + C G CTN G +RC C G+ A C DVNEC
Sbjct: 759 HLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC- 815
Query: 1331 LNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
L + C GEC NT GSF C C GY C DVDEC + C N G
Sbjct: 816 LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS--EEDLCQSGICTNTDG 873
Query: 1390 SFKCSCREGWIGNG--IKCIDLDECSNGTHQCSINAQCVNTPGSYRCA--CSEGF-TGDG 1444
SF+C C G C+D+DEC + +C N+PGSYRC C G+ G
Sbjct: 874 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 933
Query: 1445 FTCSDVDECAE-NINLCENGQCLNVPGAYRCE--CEMGFTPASDSRSCQDIDECSFQNIC 1501
TC DVDEC E +C +C N PG+YRC C+ G+ P CQD+DEC ++ C
Sbjct: 934 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFC 992
Query: 1502 -VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN-CVNGLCVNTPGRYECNCP 1559
C NLPG F C+CD GYE R G +C D++EC C LC N G + C CP
Sbjct: 993 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1052
Query: 1560 --PDFQLNPTGVGCVDNRVGNCYL-----------------------------KFGPRGD 1588
P+ + +P CV R + GP G
Sbjct: 1053 NSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1111
Query: 1589 GSL----------SCNTEIGVGVSRSSCCCSLGKAWGNPC--ETCPPVNSTEYYTLCPGG 1636
G +C+ + V+ CCC++G+ WG+ C + CP + EY +LCP G
Sbjct: 1112 GRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG 1171
Query: 1637 EGF-RPNPITIILEDIDECQELPG-LCQGGNCINTFGSFQCECPQGYYLSEDTRICEDID 1694
G+ P+ + D+DECQ +C+ G C+NT + C C GYY C D D
Sbjct: 1172 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1231
Query: 1695 ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC-------MDMRKSFCYRSYNG- 1746
EC C G C NT+G+Y C C P + C +D C++
Sbjct: 1232 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1291
Query: 1747 TTCEN-ELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
C + L T CCC Y G+AW C CP + DF+ +C
Sbjct: 1292 LVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALC 1335
Score = 491 bits (1264), Expect = e-138
Identities = 338/1034 (32%), Positives = 471/1034 (45%), Gaps = 139/1034 (13%)
Query: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
CP G+ + CED+DEC A G C G C NT G YTC+CP ++ + +C+
Sbjct: 277 CPTGFERVNGS--CEDVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
Query: 1737 -----KSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
K C+R C + N+TK++CCC+ VGKAW + C+ CP G+ F+ IC
Sbjct: 334 VISEAKGPCFRVLRDGGCSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREIC 392
Query: 1792 GNIPGFTFDIHTGK-----------AVDIDECKEIPGIC---ANGVCINQIGSFRCECPT 1837
PG+ + + V + + + +P A + +++ P
Sbjct: 393 PAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 452
Query: 1838 GFSYNDLLLVC------EDIDECSNGDNLCQRNAD------CINSPGSYRCECAAGFKLS 1885
+L L +I E +CQRN CI+ P Y C C +GF+LS
Sbjct: 453 PRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 512
Query: 1886 PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HP 1942
P G C+D +EC +P C+ G C + GS++C+C GF+A C+DVDEC R P
Sbjct: 513 PQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 572
Query: 1943 CGNGTCKNTVGSYNCLCYPGFELT-HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLC 2001
C G C+NT GS+ C+C G++ H C D+DEC+ G +C G C N GSF+C+C
Sbjct: 573 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVC 631
Query: 2002 NEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
G+ G C D +EC P C PG C N GSF C CP G+ + C D++
Sbjct: 632 PAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 687
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ---------SFCFTNFE 2109
EC P C +G C NT G FQC+CP GF + G C D + C +
Sbjct: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPG 747
Query: 2110 NGKC-SVPKAFNTTKAKC-----CCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
+ +C + P + + +C C S P G C + E +F+ C G+
Sbjct: 748 SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT----NTEGSFRCSCAPGYRAPS 803
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
DVNECLE +G+C+NTDGSF C C GY G C+D DECS + C
Sbjct: 804 GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC 863
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQ-NPLLC-AFRCMNTFGSYECT-- 2278
+G CTN GSFEC C G GP + +C D++EC + P LC + RC N+ GSY C
Sbjct: 864 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 923
Query: 2279 CPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFMC--ICPPGMARRPDGEG 2335
C GY + C D+DEC E G C ++ C+N G++ C C PG P G G
Sbjct: 924 CDPGYH-AGPEGTCDDVDECQEYGPEICGAQ--RCENTPGSYRCTPACDPGYQPTPGG-G 979
Query: 2336 CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC 2395
C D +ECR + + C N+ GS++C C++G++ + G C+D + E LQ +C
Sbjct: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE----CETLQGVC 1035
Query: 2396 QMASSSRNLVTKSECCCDG---------GRGWGHQCELCPLPGT---AQYKKICPHGP-- 2441
A+ N+ C C GR + PG+ A + P P
Sbjct: 1036 G-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPP 1094
Query: 2442 ------------GYTTDGRDIDEC---KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
G GR EC P+ C N N C C VG + G
Sbjct: 1095 PPLPRRPSTPRQGPVGSGR--RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWG 1148
Query: 2487 TSCIDLDECSQSPKPCNYICKNTE-GSYQCSCP--RGYVLQE-DGKTCKDLDECQT-KQH 2541
+ C Q C TE YQ CP RGY+ D +D+DECQ +
Sbjct: 1149 SGC----RIQQ--------CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1196
Query: 2542 NCQF-LCVNTLGGFTCKCPPGFTQH--HTACIDNNECGSQPSLCGAKGICQNTPGSFSCE 2598
C+ +CVNT G++C C G+ H CIDN+EC + C G C NT GS+ C
Sbjct: 1197 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCT 1255
Query: 2599 CQRGFSLDATGLNC 2612
C+ LD + C
Sbjct: 1256 CEPPLVLDGSQRRC 1269
Score = 472 bits (1214), Expect = e-132
Identities = 368/1217 (30%), Positives = 501/1217 (41%), Gaps = 201/1217 (16%)
Query: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
C G G + D C+E + N + ++ P C GF + S C+D+DEC
Sbjct: 244 CCRG-AGLAWGVHDCQLCSERLG---NSERVSAPDG---PCPTGFERVNGS--CEDVDEC 294
Query: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYE 1555
+ C G C N G + C+C DG+ LD + +C I+ G C
Sbjct: 295 ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS----QHVISEAKGPCFRVLRDGG 350
Query: 1556 CNCPPDFQLNPTGVGCVDNRVGNCYLK-------FGPRGDGSLSCNTEIGVGVSRSSCC- 1607
C+ P N T C +RVG + + FG G + C G S S
Sbjct: 351 CSLP--ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI-CPAGPGYHYSASDLRY 407
Query: 1608 -----------CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF---RPNPITIILE---- 1649
SL + P + P + L P E RP P +
Sbjct: 408 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 467
Query: 1650 ---DIDE-------CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
+I E CQ P +C G CI+ + C C G+ LS C D+DEC
Sbjct: 468 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 527
Query: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
P C PG C N+ G++ C+C P + C+D+ + C+R
Sbjct: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CHR---------------VP 570
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1819
C ++G+ N TPG+ F +C G+ H D+DEC + PG+C
Sbjct: 571 PPC----DLGRCEN-------TPGS--FLCVCP--AGYQAAPHGASCQDVDECTQSPGLC 615
Query: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVC-EDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
G C N GSFRC CP GF + C ED+DEC+ C C N+ GS+ C C
Sbjct: 616 GRGACKNLPGSFRCVCPAGFRGS----ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCAC 670
Query: 1879 AAGFK-LSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDE 1937
AGF+ P C D +EC P C++G C + +GS+QC+C GF+ + + C DVDE
Sbjct: 671 PAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE 730
Query: 1938 CERH-PCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGS 1996
CE H C C N+ GS+ C P H C D+DECSS +G C N GS
Sbjct: 731 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 790
Query: 1997 FKCLCNEGYELTPDGK--NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE--VKSE 2052
F+C C GY P G+ C D NEC+ G C N +GSF C C PGY +
Sbjct: 791 FRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
Query: 2053 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGK 2112
+C+D++EC E+ ++C G CTNT G F+C+CPPG + C D + E G
Sbjct: 850 SCLDVDECSEE-DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDEC-----RERG- 902
Query: 2113 CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
P + + C PG C +D C G+ P T +DV
Sbjct: 903 ---PALCGSQR----CENSPGS------YRCVRD--------CDPGYHAGP--EGTCDDV 939
Query: 2173 NECLE-SPGICSNGQCINTDGSFRC--ECPMGYNLDYTGVRCVDTDECSIGNPCG-NGTC 2228
+EC E P IC +C NT GS+RC C GY G C D DEC + CG + C
Sbjct: 940 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVC 998
Query: 2229 TNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLC-AFRCMNTFGSYECTCPIGYALR 2286
N+ GSF+C C++G+E +C D+NEC +C A C N GS+ C CP
Sbjct: 999 QNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP------ 1052
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICP-----PGMARRPDGEGCVDENE 2341
E R + + GTF P P + RP
Sbjct: 1053 ----------NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP------PPPP 1096
Query: 2342 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 2401
+P G +GS R EC ++ + DN +
Sbjct: 1097 LPRRPSTPRQGP----VGSGRREC----YFDTAAPDACDN-----------------ILA 1131
Query: 2402 RNLVTKSECCCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG------RDIDEC 2453
RN VT ECCC G GWG C + CP TA+Y+ +CPHG GY RD+DEC
Sbjct: 1132 RN-VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
Query: 2454 KVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEG 2511
++ +C +G C+NT + C+C GY CID DEC+ C C NT G
Sbjct: 1191 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1250
Query: 2512 SYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCP---PGFTQHHTA 2568
SY C+C VL + C +E Q+ N C P T
Sbjct: 1251 SYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECC 1309
Query: 2569 CIDNNECGSQPSLCGAK 2585
C+ G +LC A+
Sbjct: 1310 CLYGEAWGMDCALCPAQ 1326
Score = 458 bits (1179), Expect = e-128
Identities = 293/923 (31%), Positives = 401/923 (43%), Gaps = 156/923 (16%)
Query: 1453 CAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTCNNLPG 1511
C N +C G+C++ P Y C C+ GF + C D+DEC C G C N PG
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 1512 MFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVG 1570
F C+C G+ C D+DEC P C G C NTPG + C CP +Q P G
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 1571 CVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYY 1630
C D V C G G G+ C+ P +
Sbjct: 602 CQD--VDECTQSPGLCGRGA---------------------------CKNLPG----SFR 628
Query: 1631 TLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
+CP G FR + ED+DEC + P C G C NT GSF C CP G+ C
Sbjct: 629 CVCPAG--FRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
Query: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
+D+DEC P C G C NT G++ C+CP + G C D+ + CE
Sbjct: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE-----------CE 732
Query: 1751 NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDID 1810
N L C V + C CP+ +H G+ D+D
Sbjct: 733 NHLA-------CPGQECVNSPGSFQCRTCPSG----------------HHLHRGRCTDVD 769
Query: 1811 ECKEIPGICA-NGVCINQIGSFRCECPTGF-SYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
EC C +G C N GSFRC C G+ + + C D++EC GD C + +C+
Sbjct: 770 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD-FCFPHGECL 828
Query: 1869 NSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQ 1927
N+ GS+ C CA G++ P GA C+D +EC E ++C G+C + GS++CIC G +A
Sbjct: 829 NTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGP 887
Query: 1928 DQTMCMDVDEC-ERHP--CGNGTCKNTVGSYNCL--CYPGFELTHNNDCLDIDECSSFFG 1982
D C+DVDEC ER P CG+ C+N+ GSY C+ C PG+ C D+DEC +
Sbjct: 888 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 947
Query: 1983 QVCRNGRCFNEIGSFKCL--CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
++C RC N GS++C C+ GY+ TP G C D +EC + CQNL GSF+
Sbjct: 948 EICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
Query: 2041 CICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGF----------------QCL 2082
C+C GYE + +C+D+NEC+ +C C N G F +C+
Sbjct: 1007 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1066
Query: 2083 CPPGFVLSDNG---------------------RRCFDTRQS--------FCFTNFENGKC 2113
P + G RR RQ F C
Sbjct: 1067 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1126
Query: 2114 SVPKAFNTTKAKCCCSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGTVPSLHDT--R 2169
A N T +CCC+ GEGWG C + CP + +Q LCP+G G + D R
Sbjct: 1127 DNILARNVTWQECCCTV--GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1184
Query: 2170 EDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2227
DV+EC L +C +G C+NT + C C GY + C+D DEC+ P C G
Sbjct: 1185 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1244
Query: 2228 CTNVIGSFECNCNEGFE-PGPMMNC---------EDINECAQN---PLLCAFRCMNTFGS 2274
C N +GS+ C C G C +++ C Q L+C+ ++ +
Sbjct: 1245 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQAT 1304
Query: 2275 Y-ECTCPIGYALREDQKMCKDLD 2296
Y EC C G A D +C D
Sbjct: 1305 YTECCCLYGEAWGMDCALCPAQD 1327
Score = 426 bits (1094), Expect = e-118
Identities = 358/1219 (29%), Positives = 493/1219 (40%), Gaps = 250/1219 (20%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQPCRRGFIPNIRTG 272
G CF ++ C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 220 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 273
Query: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
+ CP G ++ CED+DEC+ G C+ G
Sbjct: 274 ---------------------------DGPCPTGFER--VNGSCEDVDECAT-GGRCQHG 303
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQ 387
EC+NT G Y CVCP G++ + S CI Q G CF L +G C+ + +TK
Sbjct: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 363
Query: 388 CCCEP-GRCWGIGTIPEACPVRGSEEYRRLCMDG--------------LPMGGIPGS--- 429
CCC G+ WG G + CP GSE +R +C G P+G P
Sbjct: 364 CCCSRVGKAWGRGC--QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSL 421
Query: 430 -------AGSRPGGTGGNGFAPSGNGNGYG-------PGGTGFIP-IPGGNGFSPGVGGA 474
A SRP GF P+ PG +P IP G P + +
Sbjct: 422 SQPRTLPATSRPSA----GFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPES 475
Query: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-C 533
G +G +C+ + +C GRCI S Y C C+ G++ G C
Sbjct: 476 GPSSG-----------------MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC 518
Query: 534 IDVDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
IDVDEC PC G C N+PGS+ C C GF+ P C+D+DEC + C GRC
Sbjct: 519 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 578
Query: 592 VNTDGSFQCICNAGFELTTDGKNCVDHDECTTT-NMCLNGMCINEDGSFKCICKPGFVLA 650
NT GSF C+C AG++ G +C D DECT + +C G C N GSF+C+C GF
Sbjct: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--- 635
Query: 651 PNGRYCT-DVDEC-QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--------- 699
G C DVDEC Q P C G C N+ GSF C CP G G C D
Sbjct: 636 -RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 694
Query: 700 --THMRSTCYGGIKKGVCVRPFPGAVTKSEC-----------C----CANPDYGFGEPCQ 742
T+ R G + VC F SEC C C N F C+
Sbjct: 695 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF--QCR 752
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSGYE- 800
CP+ + G C+ D++EC+ C +G C N GS+RC+C GY
Sbjct: 753 TCPSGHHLH-RGRCT----------DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 801 PDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESN 859
P C D++ECL +G C NT GS++CTC PGY +C D++EC E +
Sbjct: 802 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 861
Query: 860 PCVNGACRNNLGSFNCECSPGSKLSSTGLICID----SLKGTCWLNIQDSRCEVNINGAT 915
C +G C N GSF C C PG + C+D +G Q RCE +
Sbjct: 862 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ--RCENSPGSYR 919
Query: 916 LKSECCATLGAAWGSPCE----------------RCE-------LDTACPRGLARIKGVT 952
+C A C+ RCE AC G G
Sbjct: 920 CVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 979
Query: 953 CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
C+DV+EC + C N GSF C C +G GR C+D+ +E E
Sbjct: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV---------NECET 1030
Query: 1013 IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPR------GAGF-------A 1059
+ V G A C V ++ C P+ E++ + R AG A
Sbjct: 1031 LQGVCGA----ALCENVEGSFLCVCPNSPE----EFDPMTGRCVPPRTSAGTFPGSQPQA 1082
Query: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFAL-----DMEERNCT 1114
VL RP + + P + +GS + C A ++ RN T
Sbjct: 1083 PASPVLPARPPPPPLPRRPSTPR-------QGPVGSGRRECYFDTAAPDACDNILARNVT 1135
Query: 1115 DIDECRISPDLCGSGICVNT-PGSFE------CECFEGY--ESGFMMMKNCMDIDECER- 1164
+ C + GSG + PG+ C GY SG + ++ D+DEC+
Sbjct: 1136 WQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR--DVDECQLF 1193
Query: 1165 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1224
+C+ G CVNT + C C G+ R +C+D +EC+ + C G+CVN +G+Y
Sbjct: 1194 RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYH 1253
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNG--------GCDTQCT----NSEGSY-ECSCSEG 1271
C+C P ++ C + + + G D C+ + + +Y EC C G
Sbjct: 1254 CTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1313
Query: 1272 YALMPDGRSC--ADIDECE 1288
A D C D D+ E
Sbjct: 1314 EAWGMDCALCPAQDSDDFE 1332
Score = 424 bits (1089), Expect = e-118
Identities = 299/929 (32%), Positives = 393/929 (42%), Gaps = 135/929 (14%)
Query: 1287 CENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKG 1346
C+ NP +C G+C + P Y C C GF S CIDV+EC C G CEN+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 1347 SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG--NGI 1404
SF C C G+ C DVDEC CD+ C N PGSF C C G+ +G
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGA 600
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQ 1464
C D+DEC+ C A C N PGS+RC C GF G DVDECA+ C G+
Sbjct: 601 SCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDVDECAQEPPPCGPGR 658
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI-CVFGTCNNLPGMFHCICDDGYEL 1523
C N G++ C C GF CQD+DEC+ C +G C N G F C+C G++
Sbjct: 659 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
Query: 1524 DRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLNPTGVGCVDNRVGNCYLK 1582
+ G C D+DEC + + C CVN+PG ++C CP L+ C D V C
Sbjct: 719 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD--VDECSSG 774
Query: 1583 FGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPN 1642
P G NTE C C+ G P G RP
Sbjct: 775 APPCGPHGHCTNTE-----GSFRCSCAPGYR-------------------APSG---RPG 807
Query: 1643 PITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGV 1702
P D++EC E G C+NT GSF C C GY C D+DEC + +
Sbjct: 808 PCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEEDL 862
Query: 1703 CGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMC 1762
C G C NT G++ CICPP + +C+D+ + C P +C
Sbjct: 863 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-----------CRERGP-----ALC 906
Query: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI-PGICAN 1821
++ CE P ++ + PG+ G D+DEC+E P IC
Sbjct: 907 ---------GSQRCENSP----GSYRCVRDCDPGYHAGPE-GTCDDVDECQEYGPEICGA 952
Query: 1822 GVCINQIGSFRCE--CPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
C N GS+RC C G+ C+D+DEC N + C +A C N PGS++C C
Sbjct: 953 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCD 1010
Query: 1880 AGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNG---------------- 1922
G++ + +G CVD NEC + VC LC +++GS+ C+C N
Sbjct: 1011 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1070
Query: 1923 ----FKASQDQTMCMDVDECERHPCGNGTCKNT-----VGSYNCLCYPGFELTHNNDCLD 1973
F SQ Q V P +T VGS CY F+ + C +
Sbjct: 1071 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY--FDTAAPDACDN 1128
Query: 1974 I-------DEC----SSFFGQVCRNGRC-FNEIGSFKCLCNEGYE-LTPDGKNCI--DTN 2018
I EC +G CR +C E ++ LC G L P G + D +
Sbjct: 1129 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVD 1188
Query: 2019 ECVALPGS-CSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCTNT 2075
EC C G C N + C C GY ++ CID +EC ++ C G C NT
Sbjct: 1189 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNT 1248
Query: 2076 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNF-----ENGK---CSVPKA-FNTTKAKC 2126
G + C C P VL + RRC N E G CS P+ T +C
Sbjct: 1249 VGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTEC 1308
Query: 2127 CCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
CC + GE WG C LCP D F+ LC
Sbjct: 1309 CC--LYGEAWGMDCALCPAQDSDDFEALC 1335
Score = 418 bits (1075), Expect = e-116
Identities = 350/1212 (28%), Positives = 480/1212 (39%), Gaps = 267/1212 (22%)
Query: 171 IGTYCGQPVCENG-----CQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMC 225
I + G + E+G CQ + GP RC C+ +R P T+
Sbjct: 464 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC----- 518
Query: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIP 284
+ C + GR CE P + C GF R C DVDEC +P
Sbjct: 519 ---IDVDECRRVPPPCAPGR-----CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 570
Query: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
C G C NT GSF C CPAG++ + C+D+DEC+ PG+C G C N GS+ CV
Sbjct: 571 PPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV 630
Query: 345 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWG-IGTIPE 403
CP G+ GS C + CAQE P C PGRC G+
Sbjct: 631 CPAGF----RGSACEED----------VDECAQEPPP--------CGPGRCDNTAGSFHC 668
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
ACP R G P + A S P T G G+ P
Sbjct: 669 ACPAG-----FRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP---------- 713
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCE-CN 522
GF P G+ + +D C++H C C+ + S++C C
Sbjct: 714 -MGFQPNTAGSEC----------------EDVDECENHL-ACPGQECVNSPGSFQCRTCP 755
Query: 523 MGYKQDANGDCIDVDECTSN--PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQ--ACIDID 577
G+ G C DVDEC+S PC +G C NT GS+ C C G+ R P+ + C D++
Sbjct: 756 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVN 813
Query: 578 ECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDG 637
EC++ +G C+NTDGSF C C G+ G +C+D DEC+ ++C +G+C N DG
Sbjct: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 873
Query: 638 SFKCICKPGFVLAPNGRYCTDVDECQT--PGICMNGHCINSEGSFRC--DCPPGLAVGMD 693
SF+CIC PG P+ C DVDEC+ P +C + C NS GS+RC DC PG G +
Sbjct: 874 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 933
Query: 694 GRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
G C D EC P+ + C+ P S
Sbjct: 934 G-TCDDV-------------------------DECQEYGPEICGAQRCENTP--GSYRCT 965
Query: 754 GLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
C G T G +D++EC A+ +C+NL GS++C C+ GYE GR+C+D+
Sbjct: 966 PACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1025
Query: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC---RN 868
+EC + +C LC N GS+ C CP N E + G C R
Sbjct: 1026 NECETLQGVCGAALCENVEGSFLCVCP---------------NSPEEFDPMTGRCVPPRT 1070
Query: 869 NLGSF-----NCECSP-----------GSKLSSTGLICIDSLKGTCWLN-IQDSRCEVNI 911
+ G+F SP + S+ + S + C+ + C+ +
Sbjct: 1071 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1130
Query: 912 NGATLKSECCATLGAAWGSPC--------ERCELDTACPRG---LARIKGVTC-EDVNEC 959
ECC T+G WGS C E E + CP G LA ++ DV+EC
Sbjct: 1131 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
Query: 960 EVF------PGVCPN-------------------------------------GRCVNSKG 976
++F GVC N GRCVN+ G
Sbjct: 1191 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1250
Query: 977 SFHCECPEGLTLDGTGRVC-------LDIRMEQCYLKWDED-ECIHP-VPGKFRMDACCC 1027
S+HC C L LDG+ R C LD + C+ + D C HP + + CCC
Sbjct: 1251 SYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCC 1310
Query: 1028 AVGAAWGTECEECPKPGTKEYETLC----------PRGAGFA-------NRGDVLTGRPF 1070
G AWG +C CP + ++E LC PR GF + G G P+
Sbjct: 1311 LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPY 1370
Query: 1071 YKDINECKAFP-------------GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDID 1117
++ A P YG R + F+ + G E
Sbjct: 1371 GPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFE---DDGGPYGESEAPAPPGP 1427
Query: 1118 ECR---ISPDLCGSGICVNTP---GSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG 1171
R S D S P GS+ E YE + + C +D C
Sbjct: 1428 GTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEE--LEAEECGILDG-------CTN 1478
Query: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINEC---SLSDNLCRNGKCVNMIGTYQCSCN 1228
G CV F C C G+ L +R CVDINEC + LC N +C+N G+++C C
Sbjct: 1479 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICR 1538
Query: 1229 PGYQATPDRQGC 1240
PG+ T C
Sbjct: 1539 PGFAPTHQPHHC 1550
Score = 392 bits (1007), Expect = e-108
Identities = 271/841 (32%), Positives = 363/841 (43%), Gaps = 144/841 (17%)
Query: 1983 QVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI 2042
QVC GRC + + C C+ G+ L+P G CID +EC +P C+PG C+N GSFRC+
Sbjct: 487 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 546
Query: 2043 CPPGYEV--KSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C PG+ ++ C+D++EC P C G C NTPG F C+CP G+ + +G C D
Sbjct: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
Query: 2101 QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG-H 2159
+ C++ PG C+ P +F+ +CP G
Sbjct: 607 E--------------------------CTQSPGLCGRGACKNLPG----SFRCVCPAGFR 636
Query: 2160 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
G+ EDV+EC + P C G+C NT GSF C CP G+ G C D DEC+
Sbjct: 637 GSA-----CEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 691
Query: 2220 GNP-CGNGTCTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAFR-CMNTFGSYE 2276
P C G C N GSF+C C GF+P CED++EC +N L C + C+N+ GS++
Sbjct: 692 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 750
Query: 2277 C-TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEG 2335
C TCP G+ L + C D+DEC+ G C G C N G+F C C PG R P G
Sbjct: 751 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGY-RAPSGRP 806
Query: 2336 --CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
C D NEC +G C+N GS+ C C G++ G CLD + C E L
Sbjct: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEEDL-- 862
Query: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELC--------------------PLPGTAQY 2433
CQ + N EC C G G C PG+ +
Sbjct: 863 -CQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 920
Query: 2434 KKICPHGPGYTTDGR--DIDECKVM-PNLCTNGQCINTMGSFRCF--CKVGYTTDISGTS 2488
+ C G +G D+DEC+ P +C +C NT GS+RC C GY G
Sbjct: 921 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-G 979
Query: 2489 CIDLDEC-SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFL 2546
C D+DEC ++S + +C+N GS+QC C +GY DG+ C D++EC+T Q C L
Sbjct: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAAL 1039
Query: 2547 CVNTLGGFTCKCPPG---FTQHHTACIDNNEC-----GSQPSLCGAKGICQNTP------ 2592
C N G F C CP F C+ GSQP + + P
Sbjct: 1040 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPR 1099
Query: 2593 ----------GSFSCECQRGFSLDATGLNCEDVDECDG----NHRCQHGCQNILGGYRCG 2638
GS EC + D CD N Q C + G+ G
Sbjct: 1100 RPSTPRQGPVGSGRRECY---------FDTAAPDACDNILARNVTWQECCCTVGEGWGSG 1150
Query: 2639 CP-------------------QGYIQ---HYQWNQCVDENECSNPNACGSASCYNTLGSY 2676
C +GY+ + VDE + C S C NT Y
Sbjct: 1151 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1210
Query: 2677 KCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGC-PPGYYRVGQGHCV 2734
C C +G+ + C D +EC+ + C G C NT G Y C C PP Q CV
Sbjct: 1211 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1270
Query: 2735 S 2735
S
Sbjct: 1271 S 1271
Score = 377 bits (969), Expect = e-104
Identities = 281/866 (32%), Positives = 378/866 (43%), Gaps = 143/866 (16%)
Query: 1896 CLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNTVG 1953
C P VC G C+ Y C C +GF+ S T C+DVDEC R PC G C+N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 1954 SYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
S+ C+C PGF +CLD+DEC C GRC N GSF C+C GY+ P G
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRV-PPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
Query: 2013 NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCI-DINECDEDPNICLFGS 2071
+C D +EC PG C G C+NL GSFRC+CP G+ + C D++EC ++P C G
Sbjct: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGR 658
Query: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
C NT G F C CP GF G C D + C++
Sbjct: 659 CDNTAGSFHCACPAGFRSRGPGAPCQDVDE--------------------------CARS 692
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
P CE + E +FQ +CP G + + EDV+EC E+ C +C+N+
Sbjct: 693 PPPCTYGRCE----NTEGSFQCVCPMGFQPNTAGSEC-EDVDEC-ENHLACPGQECVNSP 746
Query: 2192 GSFRCE-CPMGYNLDYTGVRCVDTDECSIGNP-CG-NGTCTNVIGSFECNCNEGFE---- 2244
GSF+C CP G++L + G RC D DECS G P CG +G CTN GSF C+C G+
Sbjct: 747 GSFQCRTCPSGHHL-HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 804
Query: 2245 -PGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL 2302
PGP C D+NEC + C+NT GS+ CTC GY C D+DEC+E
Sbjct: 805 RPGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE- 860
Query: 2303 HDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK-PGICENGRCVNIIGSY 2361
C+S +C N G+F CICPPG PD C+D +ECR + P +C + RC N GSY
Sbjct: 861 DLCQSG--ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918
Query: 2362 RC--ECNEGFQSSSSGT-----ECLDNRQGLCFAEVLQTI-----CQMASSSRNLVTKSE 2409
RC +C+ G+ + GT EC + +C A+ + C A T
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
Query: 2410 CCCD----GGRGWGHQCELCP-LPGTAQYKKICPHGPGYTTDGR---DIDECKVMPN--- 2458
C D R + +C LPG+ Q +C G DGR D++EC+ +
Sbjct: 979 GCQDVDECRNRSFCGAHAVCQNLPGSFQC--LCDQGYEGARDGRHCVDVNECETLQGVCG 1036
Query: 2459 --LCTNGQ------CINTMGSF-----RCF---CKVGY---------------------- 2480
LC N + C N+ F RC G
Sbjct: 1037 AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPP 1096
Query: 2481 -----TTDISGTSCIDLDEC---SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD 2532
+T G EC + +P C+ I +C C G + G C+
Sbjct: 1097 LPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR- 1152
Query: 2533 LDECQ-TKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNT 2591
+ +C T+ Q LC + G P G D +EC G+C NT
Sbjct: 1153 IQQCPGTETAEYQSLCPHGRGYLA---PSGDLSLRR---DVDECQLFRDQVCKSGVCVNT 1206
Query: 2592 PGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQW 2649
+SC C G+ L C D DEC D C+ G C N +G Y C C +
Sbjct: 1207 APGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ 1266
Query: 2650 NQCVDENECSNPNACGSASCYNTLGS 2675
+CV S + G C+ +G+
Sbjct: 1267 RRCVSNESQSLDDNLG--VCWQEVGA 1290
Score = 372 bits (956), Expect = e-102
Identities = 274/835 (32%), Positives = 375/835 (44%), Gaps = 104/835 (12%)
Query: 1959 CYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2018
C GFE N C D+DEC++ G C++G C N G + C+C +G+ L +CI +
Sbjct: 277 CPTGFERV-NGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
Query: 2019 EC---------VALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICL- 2068
V G CS +N+ C C + C +C
Sbjct: 334 VISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC----------QLCPP 382
Query: 2069 FGSCTNTPGGFQCLCP--PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKC 2126
FGS GF+ +CP PG+ S + R ++TR G+ P+ +
Sbjct: 383 FGS-----EGFREICPAGPGYHYSASDLR-YNTRPL--------GQ-EPPRVSLSQPRTL 427
Query: 2127 CCSKMPGEGWGDPCELCPKDD---------EVAFQDLCPYGHGTVPSLHDTREDVNECLE 2177
+ P G+ L P+ + E+ + + T P + ++ C
Sbjct: 428 PATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW---TGPEIPESGPSSGMCQR 484
Query: 2178 SPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFE 2236
+P +C G+CI+ + C C G+ L G RC+D DEC + PC G C N GSF
Sbjct: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 544
Query: 2237 CNCNEGFEPGP-MMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 2294
C C GF GP C D++EC + P C RC NT GS+ C CP GY C+D
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
Query: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENGR 2353
+DEC + C RG CKNL G+F C+CP G G C D +EC +P C GR
Sbjct: 605 VDECTQSPGLC-GRG-ACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR 658
Query: 2354 CVNIIGSYRCECNEGFQSSSSGTECLDNRQ----------GLC--FAEVLQTICQMASSS 2401
C N GS+ C C GF+S G C D + G C Q +C M
Sbjct: 659 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
Query: 2402 RNLVTKSECC--CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR--DIDECKV-M 2456
++ E C+ Q E PG+ Q + CP G + GR D+DEC
Sbjct: 719 NTAGSECEDVDECENHLACPGQ-ECVNSPGSFQC-RTCPSG-HHLHRGRCTDVDECSSGA 775
Query: 2457 PNLCTNGQCINTMGSFRCFCKVGYTTDISGT--SCIDLDECSQSPKPCNY-ICKNTEGSY 2513
P +G C NT GSFRC C GY SG C D++EC + + C NT+GS+
Sbjct: 776 PPCGPHGHCTNTEGSFRCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPHGECLNTDGSF 834
Query: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QHHTACID 2571
C+C GY G +C D+DEC + +C NT G F C CPPG +C+D
Sbjct: 835 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
Query: 2572 NNECGSQ-PSLCGAKGICQNTPGSFSC--ECQRGFSLDATGLNCEDVDECD--GNHRC-Q 2625
+EC + P+LCG++ C+N+PGS+ C +C G+ G C+DVDEC G C
Sbjct: 895 VDECRERGPALCGSQR-CENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGA 952
Query: 2626 HGCQNILGGYRC--GCPQGYIQHYQWNQCVDENECSNPNACGS-ASCYNTLGSYKCACPS 2682
C+N G YRC C GY Q C D +EC N + CG+ A C N GS++C C
Sbjct: 953 QRCENTPGSYRCTPACDPGY-QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1011
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCP--PGYYRVGQGHCV 2734
G+ + C DVNEC + + C C N EG +LC CP P + G CV
Sbjct: 1012 GYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1066
Score = 315 bits (806), Expect = 5e-85
Identities = 299/1019 (29%), Positives = 385/1019 (37%), Gaps = 251/1019 (24%)
Query: 29 QPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNV 88
+P+P P PRP P S + PE E G +S + +R Q + GP
Sbjct: 444 EPRPEPRPDPRPGP------ELPLPSIPAWTGPEIPESGP--SSGMCQRNPQ--VCGPGR 493
Query: 89 CGSRFHSYCC---PGWKTLPGGNQCI-------VP------ICRNS-------CGDGFCS 125
C SR Y C G++ P G +CI VP C NS CG GF +
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRA 553
Query: 126 RPNMC-------------TCSSGQISSTCGSKSIQQCSV---RCMNGGTCAD-DHCQCQK 168
P C G+ +T GS + C +G +C D D C
Sbjct: 554 GPRAAECLDVDECHRVPPPCDLGRCENTPGS-FLCVCPAGYQAAPHGASCQDVDECTQSP 612
Query: 169 GYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQ 228
G CG+ C+N G RC C GF G CE D C +
Sbjct: 613 G----LCGRGACKN-------LPGSFRCVCPAGFRGSACEED--VDECAQEPP------- 652
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQ 288
C C T G C CPA GF CQDVDEC P C
Sbjct: 653 ----PCGPGRCDNTAG---SFHC-ACPA-------GFRSRGPGAPCQDVDECARSPPPCT 697
Query: 289 GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFC-VCPR 347
G C NT GSF+C CP G + + +CED+DEC C EC N+ GS+ C CP
Sbjct: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPS 756
Query: 348 GYVTSTDGSRCIDQRTGMCFSGL----VNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPE 403
G+ RC D C SG +G C +C C PG
Sbjct: 757 GH--HLHRGRCTD--VDECSSGAPPCGPHGHCT----NTEGSFRCSCAPG---------- 798
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
YR + RPG P + N G F P
Sbjct: 799 ---------YR--------------APSGRPG--------PCADVNECLEGDFCF---PH 824
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNM 523
G + A A G P G + L+ +D C +LC +G C T S+ C C
Sbjct: 825 GECLNTDGSFACTCAPGYRPGPRGASCLD--VDECSEE-DLCQSGICTNTDGSFECICPP 881
Query: 524 GYKQDAN-GDCIDVDECTSNP---CTNGDCVNTPGSYYC--KCHAGFQRTPTKQACIDID 577
G++ + C+DVDEC C + C N+PGSY C C G+ P + C D+D
Sbjct: 882 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP-EGTCDDVD 940
Query: 578 ECIQNG-VLCKNGRCVNTDGSFQC--ICNAGFELTTDGKNCVDHDECTTTNMC-LNGMCI 633
EC + G +C RC NT GS++C C+ G++ T G C D DEC + C + +C
Sbjct: 941 ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQ 999
Query: 634 NEDGSFKCICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCP--PGLAV 690
N GSF+C+C G+ A +GR+C DV+EC+T G+C C N EGSF C CP P
Sbjct: 1000 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1059
Query: 691 GMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGA---------------------------- 722
M GR CV + + G + P A
Sbjct: 1060 PMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYF 1118
Query: 723 ---------------VTKSECCCANPDYGFGEPC--QPCPAKNSAEFHGLCSSGVGITVD 765
VT ECCC + G+G C Q CP +AE+ LC G G
Sbjct: 1119 DTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP 1177
Query: 766 G------RDINECALDPD-ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNR 818
RD++EC L D +C +G+C N Y C C++GY CID DEC
Sbjct: 1178 SGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE 1237
Query: 819 LLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECS 878
C+ G C NT GSY CTC P V C NE +S
Sbjct: 1238 PACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQS-------------------- 1276
Query: 879 PGSKLSSTGLICIDSLKGTCWLNI-QDSRC-EVNINGATLKSECCATLGAAWGSPCERC 935
+D G CW + D C ++ +ECC G AWG C C
Sbjct: 1277 ------------LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALC 1323
Score = 310 bits (795), Expect = 1e-83
Identities = 184/517 (35%), Positives = 244/517 (47%), Gaps = 59/517 (11%)
Query: 2257 CAQNPLLCA-FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNL 2315
C +NP +C RC++ Y C C G+ L C D+DEC C C+N
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG--RCENS 539
Query: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSG 2375
G+F C+C PG P C+D +EC P C+ GRC N GS+ C C G+Q++ G
Sbjct: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
Query: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK 2435
C D + T+S C GRG C+ LPG+ ++
Sbjct: 600 ASCQDVDE---------------------CTQSPGLC--GRG---ACK--NLPGS--FRC 629
Query: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
+CP G + D+DEC P C G+C NT GSF C C G+ + G C D+DEC
Sbjct: 630 VCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 689
Query: 2496 SQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
++SP PC Y C+NTEGS+QC CP G+ G C+D+DEC+ CVN+ G F
Sbjct: 690 ARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 749
Query: 2555 TCK-CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLN-C 2612
C+ CP G H C D +EC S CG G C NT GSF C C G+ + C
Sbjct: 750 QCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPC 809
Query: 2613 EDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCY 2670
DV+EC +G+ HG C N G + C C GY + C+D +ECS + C S C
Sbjct: 810 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 869
Query: 2671 NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG---CSNTEGGYLC--GCPPGY 2725
NT GS++C CP G ++C DV+EC + P G C N+ G Y C C PGY
Sbjct: 870 NTDGSFECICPPGHRAGPDLASCLDVDEC-RERGPALCGSQRCENSPGSYRCVRDCDPGY 928
Query: 2726 YRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEAC 2762
+ +G C +VDE PE C
Sbjct: 929 HAGPEGTC---------------DDVDECQEYGPEIC 950
Score = 235 bits (599), Expect = 5e-61
Identities = 168/517 (32%), Positives = 229/517 (44%), Gaps = 81/517 (15%)
Query: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----- 2322
C EC P+ LR + C+ A G+HDC+ +C +G +
Sbjct: 222 CFRELRGGECASPLP-GLRTQEVCCRGAG-LAWGVHDCQ----LCSERLGNSERVSAPDG 275
Query: 2323 -CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
CP G R C D +EC T G C++G C N G Y C C +GF SS + C+
Sbjct: 276 PCPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 332
Query: 2382 R-----QGLCFAEVLQTICQMASSSRNLVTKSECCCDG-GRGWGHQCELCPLPGTAQYKK 2435
+G CF + C + RN +TK CCC G+ WG C+LCP G+ +++
Sbjct: 333 HVISEAKGPCFRVLRDGGCSLPIL-RN-ITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
Query: 2436 ICPHGPGYTTDGRD----------------IDECKVMPNLCTNGQCINTMGSFRCFCKVG 2479
ICP GPGY D + + + +P T+ + + R +
Sbjct: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLP--ATSRPSAGFLPTHRLEPRPE 448
Query: 2480 YTTD-----------ISGTSCIDLDECSQSPKPCN---YICKNTEGSYQC-SCPRGYV-- 2522
D I + ++ E S C +C G +C S P GY
Sbjct: 449 PRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC----GPGRCISRPSGYTCA 504
Query: 2523 ------LQEDGKTCKDLDECQTKQHNC-QFLCVNTLGGFTCKCPPGFTQHHTA--CIDNN 2573
L G C D+DEC+ C C N+ G F C C PGF A C+D +
Sbjct: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
Query: 2574 ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNI 2631
EC P C G C+NTPGSF C C G+ G +C+DVDEC C G C+N+
Sbjct: 565 ECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL 623
Query: 2632 LGGYRCGCPQGYIQHYQWNQC-VDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQF 2689
G +RC CP G ++ + C D +EC+ P CG C NT GS+ CACP+GF
Sbjct: 624 PGSFRCVCPAG----FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 679
Query: 2690 SSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
+ C DV+EC+ S PC YG C NTEG + C CP G+
Sbjct: 680 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
Score = 129 bits (324), Expect = 4e-29
Identities = 108/389 (27%), Positives = 152/389 (39%), Gaps = 50/389 (12%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPLPGTAQYKKICPHGPG 2442
G CF E+ C AS L T+ CC G WG H C+LC + P GP
Sbjct: 220 GYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPC 277
Query: 2443 YTTDGR------DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
T R D+DEC C +G+C NT G + C C G+ D S +SCI S
Sbjct: 278 PTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVIS 336
Query: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC 2556
++ PC + ++ CS P + + C + + + CQ GF
Sbjct: 337 EAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--GCQLCPPFGSEGFRE 390
Query: 2557 KCPPGFTQHHTAC---IDNNECGSQP---SLCGAKGI-CQNTPGSFSCECQR-------- 2601
CP G H++A + G +P SL + + + P + R
Sbjct: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 450
Query: 2602 -----GFSLDATGLNC----EDVDECDGNHRCQHG--------CQNILGGYRCGCPQGYI 2644
G L + E + + CQ C + GY C C G+
Sbjct: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
Query: 2645 QHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
Q +C+D +EC P C C N+ GS++C C GF ++ C DV+EC
Sbjct: 511 LSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 570
Query: 2704 NPCNYG-CSNTEGGYLCGCPPGYYRVGQG 2731
PC+ G C NT G +LC CP GY G
Sbjct: 571 PPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
Score = 71.6 bits (174), Expect = 1e-11
Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 1262 GSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK 1321
GSY S +E Y + + C +D C N G+C +P + C C+DG+ M
Sbjct: 1452 GSYAGSLAEPYEEL-EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRM 1503
Query: 1322 TCIDVNECD---LNSNICMFGECENTKGSFICHCQLGYS 1357
C+D+NECD S +C+ C NT GSF C C+ G++
Sbjct: 1504 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
Score = 67.4 bits (163), Expect = 2e-10
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1491 DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC-----ADPINCVNG 1545
+ +EC + C G C +P F C C DGY LD T C DI+EC A P+ CVN
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL-CVNA 1524
Query: 1546 LCVNTPGRYECNCPPDF 1562
C+NT G + C C P F
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541
Score = 66.2 bits (160), Expect = 4e-10
Identities = 37/96 (38%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 2156 PYGHGTVPSLHDTREDVN--ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVD 2213
P G SL + E++ EC G C+NG+C+ F C C GY LD T + CVD
Sbjct: 1449 PEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
Query: 2214 TDECSIGNP----CGNGTCTNVIGSFECNCNEGFEP 2245
+EC C N C N GSF C C GF P
Sbjct: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP 1543
Score = 65.9 bits (159), Expect = 6e-10
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 616 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ----TPGICMNG 671
++ +EC + C NG C+ F C C G+ L C D++EC +C+N
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
C+N++GSFRC C PG A C R+
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
Score = 65.5 bits (158), Expect = 7e-10
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 2015 IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPN---ICLF 2069
++ EC L G C+ G C + F C C GY + C+DINECDE +C+
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 2070 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C NT G F+C+C PGF + C R
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 65.1 bits (157), Expect = 1e-09
Identities = 33/79 (41%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC---VALPGSCS 2028
L+ +EC G C NGRC F C C +GY L C+D NEC A C
Sbjct: 1465 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 2029 PGTCQNLEGSFRCICPPGY 2047
C N +GSFRCIC PG+
Sbjct: 1523 NARCLNTDGSFRCICRPGF 1541
Score = 64.7 bits (156), Expect = 1e-09
Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
Query: 2449 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQ----SPKPCNY 2504
+ +EC ++ CTNG+C+ F C C GY D++ +C+D++EC + SP N
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2505 ICKNTEGSYQCSCPRGY 2521
C NT+GS++C C G+
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541
Score = 64.3 bits (155), Expect = 2e-09
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query: 2103 FCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWG-DPCELCPK----DDEVAFQD-LCP 2156
+CF G+C+ P T+ CC + G WG C+LC + + V+ D CP
Sbjct: 221 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 278
Query: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
G V + + EDV+EC G C +G+C NT G + C CP G+ LD + C+
Sbjct: 279 TGFERV---NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 334
Query: 2217 CSIGNPCGNGTCTNVIGSFECN 2238
S G C V+ C+
Sbjct: 335 ISE----AKGPCFRVLRDGGCS 352
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 2212 VDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPG-PMMNCEDINEC----AQNPLLCAF 2266
++ +EC I + C NG C V F C C +G+ M C DINEC A +PL
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2267 RCMNTFGSYECTCPIGYALREDQKMC 2292
RC+NT GS+ C C G+A C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 63.9 bits (154), Expect = 2e-09
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL---LCRG 1171
+ +EC I D C +G CV P F C CF+GY M C+DI+EC+ LC
Sbjct: 1466 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMA-CVDINECDEAEAASPLCVN 1523
Query: 1172 GTCVNTEGSFQCDCPLG-------HELSPSR 1195
C+NT+GSF+C C G H +P+R
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 63.2 bits (152), Expect = 4e-09
Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 1891 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP-----CGN 1945
++ EC I + C++G CV + + C C +G++ + C+D++EC+ C N
Sbjct: 1465 LEAEEC-GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 1946 GTCKNTVGSYNCLCYPGFELTH 1967
C NT GS+ C+C PGF TH
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTH 1545
Score = 62.4 bits (150), Expect = 6e-09
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD--GFTCSDVDECAEN---INL 1459
+C LD C+NG +CV P + C C +G+ D C D++EC E L
Sbjct: 1469 ECGILDGCTNG--------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1520
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
C N +CLN G++RC C GF P C
Sbjct: 1521 CVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1199 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG----CD 1254
++ EC + D C NG+CV + + C C GY+ R C DI+EC +
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCA 1282
+C N++GS+ C C G+A CA
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
Query: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC---SIIPGICETG 332
+ +EC + G C G C+ F CRC G++ T C DI+EC +C
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
C NT GS+ C+C G+ + C R
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 59.3 bits (142), Expect = 5e-08
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC---FAHPGVCGPG 1706
+ +EC L G C G C+ F C C GY L C DI+EC A +C
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
C NT G++ CIC P + + H+C R
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 57.8 bits (138), Expect = 2e-07
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 1933 MDVDECE-RHPCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDEC--SSFFGQVCRNG 1988
++ +EC C NG C + C C+ G+ L C+DI+EC + +C N
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 1989 RCFNEIGSFKCLCNEGYELTPDGKNC 2014
RC N GSF+C+C G+ T +C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 57.8 bits (138), Expect = 2e-07
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGD---NLCQR 1863
++ +EC + G C NG C+ F C C G+ + + C DI+EC + LC
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV- 1522
Query: 1864 NADCINSPGSYRCECAAGF 1882
NA C+N+ GS+RC C GF
Sbjct: 1523 NARCLNTDGSFRCICRPGF 1541
Score = 57.8 bits (138), Expect = 2e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 1242 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDEC---ENNPDICDGGQ 1298
+ +EC I++G + +C + C C +GY L +C DI+EC E +C +
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 1299 CTNIPGEYRCLCYDGFMASMDMKTC 1323
C N G +RC+C GF + C
Sbjct: 1526 CLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 2653 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC----SSSKNPCNY 2708
++ EC + C + C + C C G+ D AC D+NEC ++S N
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQGH 2732
C NT+G + C C PG+ Q H
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPH 1548
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 1449 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC----SFQNICVFG 1504
+ +EC ++ C NG+C+ VP + C C G+ +C DI+EC + +CV
Sbjct: 1466 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 1505 TCNNLPGMFHCICDDGY 1521
C N G F CIC G+
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541
Score = 54.7 bits (130), Expect = 1e-06
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 1848 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPN---VC 1903
C +D C+NG C+ P + C C G++L ACVD NEC E +C
Sbjct: 1470 CGILDGCTNGR--------CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1521
Query: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMC 1932
+ C++ GS++CIC GF + C
Sbjct: 1522 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 54.3 bits (129), Expect = 2e-06
Identities = 71/269 (26%), Positives = 96/269 (35%), Gaps = 61/269 (22%)
Query: 29 QPQPP--PPKPPRPQPPPQQVRSAT--AGSEGGFLAPEYREEGAAVA-SRVRRRG---QQ 80
QPQ P P P RP PPP R +T G G Y + A A + R Q+
Sbjct: 1079 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1138
Query: 81 DVLRGPNVCGSRFHSYCCPGWKT------LPGGNQCIVPI-----------CR----NSC 119
GS CPG +T P G + P C+ C
Sbjct: 1139 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1198
Query: 120 GDGFC--SRPN-MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKG----YIG 172
G C + P C CS+G T + C++ CAD+ C+ G +G
Sbjct: 1199 KSGVCVNTAPGYSCYCSNGYYYHT--------QRLECIDNDECADEEPACEGGRCVNTVG 1250
Query: 173 TY---CGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVN-NQMCQGQ 228
+Y C P+ +G Q RC+ + D G C+ +V + +C
Sbjct: 1251 SYHCTCEPPLVLDGSQR--RCV-----------SNESQSLDDNLGVCWQEVGADLVCSHP 1297
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQ 257
T T CC G AWG C +CPAQ
Sbjct: 1298 RLDRQATYTECCCLYGEAWGMDCALCPAQ 1326
Score = 52.8 bits (125), Expect = 5e-06
Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 21/166 (12%)
Query: 90 GSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC 149
G R CC G G + C + R + + C +++ +C + + +C
Sbjct: 237 GLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSC--EDVDEC 294
Query: 150 SVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCER 209
+ GG C C +G G C VC +G + +R +C+ + +
Sbjct: 295 AT----GGRCQHGECANTRG--GYTC---VCPDGF-----LLDSSRSSCISQHVISEAK- 339
Query: 210 DYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
GPCF + + C + + + CC+ +G+AWG C++CP
Sbjct: 340 ----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 381
Score = 52.8 bits (125), Expect = 5e-06
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 1324 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE--IGAHNCDMH 1381
++ EC + C G C F C C GY + C D++EC+ A ++
Sbjct: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 1382 ASCLNIPGSFKCSCREGW 1399
A CLN GSF+C CR G+
Sbjct: 1524 ARCLNTDGSFRCICRPGF 1541
Score = 52.8 bits (125), Expect = 5e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 2614 DVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSAS 2668
+ +EC C +G C + G+ C C GY CVD NEC A C +A
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 2669 CYNTLGSYKCACPSGFS 2685
C NT GS++C C GF+
Sbjct: 1526 CLNTDGSFRCICRPGFA 1542
Score = 52.4 bits (124), Expect = 7e-06
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 1739 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN-KPCEPCPTPGTADFKTICGNIPGF 1797
+C+R G C + LP T+ +CC G AW C+ C + + P
Sbjct: 221 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 278
Query: 1798 T-FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGF 1839
T F+ G D+DEC G C +G C N G + C CP GF
Sbjct: 279 TGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGF 320
Score = 52.4 bits (124), Expect = 7e-06
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 2570 IDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD----GNHRCQ 2625
++ ECG G C P F+C C G+ LD T + C D++ECD + C
Sbjct: 1465 LEAEECGILDGC--TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 2626 HG-CQNILGGYRCGCPQGYIQHYQWNQC 2652
+ C N G +RC C G+ +Q + C
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 48.9 bits (115), Expect = 7e-05
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 13/113 (11%)
Query: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
GSY + Y E ++ C LD C G C + F C C G
Sbjct: 1452 GSYAGSLAEPYEELEAEE-CGILDGCTNG---------RCVRVPEGFTCRCFDGYRLDMT 1501
Query: 2333 GEGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
CVD NEC +C N RC+N GS+RC C GF + C R
Sbjct: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
Score = 45.1 bits (105), Expect = 0.001
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2490 IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFL--- 2546
++ +EC N C + C C GY L C D++EC +
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2547 -CVNTLGGFTCKCPPGFTQHH 2566
C+NT G F C C PGF H
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTH 1545
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 2233 GSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC 2292
GS+ + E +E C ++ C RC+ + C C GY L + C
Sbjct: 1452 GSYAGSLAEPYEELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMAC 1505
Query: 2293 KDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMA 2328
D++EC E + S C N G+F CIC PG A
Sbjct: 1506 VDINECDEA--EAASPLCVNARCLNTDGSFRCICRPGFA 1542
Score = 43.5 bits (101), Expect = 0.003
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPG---ICANGVCINQIGSFRCECPTGFS 1840
C G+ D+ VDI+EC E +C N C+N GSFRC C GF+
Sbjct: 1490 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
Score = 42.4 bits (98), Expect = 0.007
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 2446 DGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
D + DE + LC N +C+NT GSFRC C+ G+
Sbjct: 1507 DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 39.7 bits (91), Expect = 0.044
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 1633 CPGGEGFRPNPITIILEDIDECQELPG---LCQGGNCINTFGSFQCECPQGYYLSEDTRI 1689
C +G+R + + DI+EC E LC C+NT GSF+C C G+ +
Sbjct: 1490 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1549
Query: 1690 C 1690
C
Sbjct: 1550 C 1550
Score = 38.1 bits (87), Expect = 0.13
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 1532 DIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
+ +EC C NG CV P + C C ++L+ T + CVD
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
Score = 35.8 bits (81), Expect = 0.64
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 14/74 (18%)
Query: 149 CSVRCMNGGT-------CADDHCQCQKGYI--GTYCGQP-----VCENGCQNGGRCIGPN 194
C +RC++G T CA + G G P +C C NGG C+ P+
Sbjct: 41 CGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPD 100
Query: 195 RCACVYGFTGPQCE 208
RC C F G C+
Sbjct: 101 RCLCPPDFAGKFCQ 114
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 524 bits (1350), Expect = e-148
Identities = 369/1186 (31%), Positives = 490/1186 (41%), Gaps = 172/1186 (14%)
Query: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFG-EPCQPCPAK--NSAEFH---GLCSSG 759
C+ ++ G C P PG T+ E CC +G CQ C + NS G C +G
Sbjct: 252 CFRELRGGECASPLPGLRTQ-EVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTG 310
Query: 760 VGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVN 817
V+G D++ECA C +G C N RG Y C C G+ D+S +C I + +++
Sbjct: 311 FE-RVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC--ISQHVIS 366
Query: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFN-CE 876
G C C+ P + C + + C + G C
Sbjct: 367 EA---KGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICP 423
Query: 877 CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE 936
PG S++ D T L + R ++ TL + + G E
Sbjct: 424 AGPGYHYSAS-----DLRYNTRPLGQEPPRVSLS-QPRTLPATSRPSAGFLPTHRLEPRP 477
Query: 937 LDTACPRG-----LARIKGVTCEDVNE-------CEVFPGVCPNGRCVNSKGSFHCECPE 984
PR L I T ++ E C+ P VC GRC++ + C C
Sbjct: 478 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 537
Query: 985 GLTLDGTGRVCLDIRMEQCYLKWDEDEC-----------IHPVPGKFRMDACCCAVGAAW 1033
G L G C+D+ DEC PG FR C C G
Sbjct: 538 GFRLSPQGTRCIDV-----------DECRRVPPPCAPGRCENSPGSFR---CVCGPGFRA 583
Query: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTI 1093
G EC D++EC P C G+C NT
Sbjct: 584 GPRAAEC-------------------------------LDVDECHRVPPPCDLGRCENTP 612
Query: 1094 GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMM 1153
GSF C C +G+ +C D+DEC SP LCG G C N PGSF C C G+
Sbjct: 613 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE 672
Query: 1154 KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN 1213
D+DEC + P C G C NT GSF C CP G C D++EC+ S C
Sbjct: 673 ----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY 728
Query: 1214 GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGY 1272
G+C N G++QC C G+Q C D+DEC +C NS GS++C +C G+
Sbjct: 729 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGH 788
Query: 1273 ALMPDGRSCADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMK-TCIDVNECD 1330
L GR C D+DEC + C G CTN G +RC C G+ A C DVNEC
Sbjct: 789 HLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC- 845
Query: 1331 LNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
L + C GEC NT GSF C C GY C DVDEC + C N G
Sbjct: 846 LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS--EEDLCQSGICTNTDG 903
Query: 1390 SFKCSCREGWIGNG--IKCIDLDECSNGTHQCSINAQCVNTPGSYRCA--CSEGF-TGDG 1444
SF+C C G C+D+DEC + +C N+PGSYRC C G+ G
Sbjct: 904 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 963
Query: 1445 FTCSDVDECAE-NINLCENGQCLNVPGAYRCE--CEMGFTPASDSRSCQDIDECSFQNIC 1501
TC DVDEC E +C +C N PG+YRC C+ G+ P CQD+DEC ++ C
Sbjct: 964 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFC 1022
Query: 1502 -VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN-CVNGLCVNTPGRYECNCP 1559
C NLPG F C+CD GYE R G +C D++EC C LC N G + C CP
Sbjct: 1023 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Query: 1560 --PDFQLNPTGVGCVDNRVGNCYL-----------------------------KFGPRGD 1588
P+ + +P CV R + GP G
Sbjct: 1083 NSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1141
Query: 1589 GSL----------SCNTEIGVGVSRSSCCCSLGKAWGNPC--ETCPPVNSTEYYTLCPGG 1636
G +C+ + V+ CCC++G+ WG+ C + CP + EY +LCP G
Sbjct: 1142 GRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG 1201
Query: 1637 EGF-RPNPITIILEDIDECQELPG-LCQGGNCINTFGSFQCECPQGYYLSEDTRICEDID 1694
G+ P+ + D+DECQ +C+ G C+NT + C C GYY C D D
Sbjct: 1202 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1261
Query: 1695 ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC-------MDMRKSFCYRSYNG- 1746
EC C G C NT+G+Y C C P + C +D C++
Sbjct: 1262 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1321
Query: 1747 TTCEN-ELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
C + L T CCC Y G+AW C CP + DF+ +C
Sbjct: 1322 LVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALC 1365
Score = 491 bits (1264), Expect = e-138
Identities = 338/1034 (32%), Positives = 471/1034 (45%), Gaps = 139/1034 (13%)
Query: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
CP G+ + CED+DEC A G C G C NT G YTC+CP ++ + +C+
Sbjct: 307 CPTGFERVNGS--CEDVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 363
Query: 1737 -----KSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
K C+R C + N+TK++CCC+ VGKAW + C+ CP G+ F+ IC
Sbjct: 364 VISEAKGPCFRVLRDGGCSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREIC 422
Query: 1792 GNIPGFTFDIHTGK-----------AVDIDECKEIPGIC---ANGVCINQIGSFRCECPT 1837
PG+ + + V + + + +P A + +++ P
Sbjct: 423 PAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 482
Query: 1838 GFSYNDLLLVC------EDIDECSNGDNLCQRNAD------CINSPGSYRCECAAGFKLS 1885
+L L +I E +CQRN CI+ P Y C C +GF+LS
Sbjct: 483 PRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 542
Query: 1886 PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HP 1942
P G C+D +EC +P C+ G C + GS++C+C GF+A C+DVDEC R P
Sbjct: 543 PQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 602
Query: 1943 CGNGTCKNTVGSYNCLCYPGFELT-HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLC 2001
C G C+NT GS+ C+C G++ H C D+DEC+ G +C G C N GSF+C+C
Sbjct: 603 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVC 661
Query: 2002 NEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
G+ G C D +EC P C PG C N GSF C CP G+ + C D++
Sbjct: 662 PAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 717
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ---------SFCFTNFE 2109
EC P C +G C NT G FQC+CP GF + G C D + C +
Sbjct: 718 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPG 777
Query: 2110 NGKC-SVPKAFNTTKAKC-----CCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
+ +C + P + + +C C S P G C + E +F+ C G+
Sbjct: 778 SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT----NTEGSFRCSCAPGYRAPS 833
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
DVNECLE +G+C+NTDGSF C C GY G C+D DECS + C
Sbjct: 834 GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC 893
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQ-NPLLC-AFRCMNTFGSYECT-- 2278
+G CTN GSFEC C G GP + +C D++EC + P LC + RC N+ GSY C
Sbjct: 894 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 953
Query: 2279 CPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFMC--ICPPGMARRPDGEG 2335
C GY + C D+DEC E G C ++ C+N G++ C C PG P G G
Sbjct: 954 CDPGYH-AGPEGTCDDVDECQEYGPEICGAQ--RCENTPGSYRCTPACDPGYQPTPGG-G 1009
Query: 2336 CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC 2395
C D +ECR + + C N+ GS++C C++G++ + G C+D + E LQ +C
Sbjct: 1010 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE----CETLQGVC 1065
Query: 2396 QMASSSRNLVTKSECCCDG---------GRGWGHQCELCPLPGT---AQYKKICPHGP-- 2441
A+ N+ C C GR + PG+ A + P P
Sbjct: 1066 G-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPP 1124
Query: 2442 ------------GYTTDGRDIDEC---KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
G GR EC P+ C N N C C VG + G
Sbjct: 1125 PPLPRRPSTPRQGPVGSGR--RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWG 1178
Query: 2487 TSCIDLDECSQSPKPCNYICKNTE-GSYQCSCP--RGYVLQE-DGKTCKDLDECQT-KQH 2541
+ C Q C TE YQ CP RGY+ D +D+DECQ +
Sbjct: 1179 SGC----RIQQ--------CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1226
Query: 2542 NCQF-LCVNTLGGFTCKCPPGFTQH--HTACIDNNECGSQPSLCGAKGICQNTPGSFSCE 2598
C+ +CVNT G++C C G+ H CIDN+EC + C G C NT GS+ C
Sbjct: 1227 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCT 1285
Query: 2599 CQRGFSLDATGLNC 2612
C+ LD + C
Sbjct: 1286 CEPPLVLDGSQRRC 1299
Score = 472 bits (1214), Expect = e-132
Identities = 368/1217 (30%), Positives = 501/1217 (41%), Gaps = 201/1217 (16%)
Query: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
C G G + D C+E + N + ++ P C GF + S C+D+DEC
Sbjct: 274 CCRG-AGLAWGVHDCQLCSERLG---NSERVSAPDG---PCPTGFERVNGS--CEDVDEC 324
Query: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYE 1555
+ C G C N G + C+C DG+ LD + +C I+ G C
Sbjct: 325 ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS----QHVISEAKGPCFRVLRDGG 380
Query: 1556 CNCPPDFQLNPTGVGCVDNRVGNCYLK-------FGPRGDGSLSCNTEIGVGVSRSSCC- 1607
C+ P N T C +RVG + + FG G + C G S S
Sbjct: 381 CSLP--ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI-CPAGPGYHYSASDLRY 437
Query: 1608 -----------CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF---RPNPITIILE---- 1649
SL + P + P + L P E RP P +
Sbjct: 438 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 497
Query: 1650 ---DIDE-------CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
+I E CQ P +C G CI+ + C C G+ LS C D+DEC
Sbjct: 498 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 557
Query: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
P C PG C N+ G++ C+C P + C+D+ + C+R
Sbjct: 558 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CHR---------------VP 600
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1819
C ++G+ N TPG+ F +C G+ H D+DEC + PG+C
Sbjct: 601 PPC----DLGRCEN-------TPGS--FLCVCP--AGYQAAPHGASCQDVDECTQSPGLC 645
Query: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVC-EDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
G C N GSFRC CP GF + C ED+DEC+ C C N+ GS+ C C
Sbjct: 646 GRGACKNLPGSFRCVCPAGFRGS----ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCAC 700
Query: 1879 AAGFK-LSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDE 1937
AGF+ P C D +EC P C++G C + +GS+QC+C GF+ + + C DVDE
Sbjct: 701 PAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE 760
Query: 1938 CERH-PCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGS 1996
CE H C C N+ GS+ C P H C D+DECSS +G C N GS
Sbjct: 761 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 820
Query: 1997 FKCLCNEGYELTPDGK--NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE--VKSE 2052
F+C C GY P G+ C D NEC+ G C N +GSF C C PGY +
Sbjct: 821 FRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 879
Query: 2053 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGK 2112
+C+D++EC E+ ++C G CTNT G F+C+CPPG + C D + E G
Sbjct: 880 SCLDVDECSEE-DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDEC-----RERG- 932
Query: 2113 CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
P + + C PG C +D C G+ P T +DV
Sbjct: 933 ---PALCGSQR----CENSPGS------YRCVRD--------CDPGYHAGP--EGTCDDV 969
Query: 2173 NECLE-SPGICSNGQCINTDGSFRC--ECPMGYNLDYTGVRCVDTDECSIGNPCG-NGTC 2228
+EC E P IC +C NT GS+RC C GY G C D DEC + CG + C
Sbjct: 970 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVC 1028
Query: 2229 TNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLC-AFRCMNTFGSYECTCPIGYALR 2286
N+ GSF+C C++G+E +C D+NEC +C A C N GS+ C CP
Sbjct: 1029 QNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP------ 1082
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICP-----PGMARRPDGEGCVDENE 2341
E R + + GTF P P + RP
Sbjct: 1083 ----------NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP------PPPP 1126
Query: 2342 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 2401
+P G +GS R EC ++ + DN +
Sbjct: 1127 LPRRPSTPRQGP----VGSGRREC----YFDTAAPDACDN-----------------ILA 1161
Query: 2402 RNLVTKSECCCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG------RDIDEC 2453
RN VT ECCC G GWG C + CP TA+Y+ +CPHG GY RD+DEC
Sbjct: 1162 RN-VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1220
Query: 2454 KVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEG 2511
++ +C +G C+NT + C+C GY CID DEC+ C C NT G
Sbjct: 1221 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1280
Query: 2512 SYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCP---PGFTQHHTA 2568
SY C+C VL + C +E Q+ N C P T
Sbjct: 1281 SYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECC 1339
Query: 2569 CIDNNECGSQPSLCGAK 2585
C+ G +LC A+
Sbjct: 1340 CLYGEAWGMDCALCPAQ 1356
Score = 458 bits (1179), Expect = e-128
Identities = 293/923 (31%), Positives = 401/923 (43%), Gaps = 156/923 (16%)
Query: 1453 CAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTCNNLPG 1511
C N +C G+C++ P Y C C+ GF + C D+DEC C G C N PG
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 1512 MFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVG 1570
F C+C G+ C D+DEC P C G C NTPG + C CP +Q P G
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 1571 CVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYY 1630
C D V C G G G+ C+ P +
Sbjct: 632 CQD--VDECTQSPGLCGRGA---------------------------CKNLPG----SFR 658
Query: 1631 TLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
+CP G FR + ED+DEC + P C G C NT GSF C CP G+ C
Sbjct: 659 CVCPAG--FRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 713
Query: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
+D+DEC P C G C NT G++ C+CP + G C D+ + CE
Sbjct: 714 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE-----------CE 762
Query: 1751 NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDID 1810
N L C V + C CP+ +H G+ D+D
Sbjct: 763 NHLA-------CPGQECVNSPGSFQCRTCPSG----------------HHLHRGRCTDVD 799
Query: 1811 ECKEIPGICA-NGVCINQIGSFRCECPTGF-SYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
EC C +G C N GSFRC C G+ + + C D++EC GD C + +C+
Sbjct: 800 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD-FCFPHGECL 858
Query: 1869 NSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQ 1927
N+ GS+ C CA G++ P GA C+D +EC E ++C G+C + GS++CIC G +A
Sbjct: 859 NTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGP 917
Query: 1928 DQTMCMDVDEC-ERHP--CGNGTCKNTVGSYNCL--CYPGFELTHNNDCLDIDECSSFFG 1982
D C+DVDEC ER P CG+ C+N+ GSY C+ C PG+ C D+DEC +
Sbjct: 918 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 977
Query: 1983 QVCRNGRCFNEIGSFKCL--CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
++C RC N GS++C C+ GY+ TP G C D +EC + CQNL GSF+
Sbjct: 978 EICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQ 1036
Query: 2041 CICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGF----------------QCL 2082
C+C GYE + +C+D+NEC+ +C C N G F +C+
Sbjct: 1037 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1096
Query: 2083 CPPGFVLSDNG---------------------RRCFDTRQS--------FCFTNFENGKC 2113
P + G RR RQ F C
Sbjct: 1097 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1156
Query: 2114 SVPKAFNTTKAKCCCSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGTVPSLHDT--R 2169
A N T +CCC+ GEGWG C + CP + +Q LCP+G G + D R
Sbjct: 1157 DNILARNVTWQECCCTV--GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1214
Query: 2170 EDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2227
DV+EC L +C +G C+NT + C C GY + C+D DEC+ P C G
Sbjct: 1215 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1274
Query: 2228 CTNVIGSFECNCNEGFE-PGPMMNC---------EDINECAQN---PLLCAFRCMNTFGS 2274
C N +GS+ C C G C +++ C Q L+C+ ++ +
Sbjct: 1275 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQAT 1334
Query: 2275 Y-ECTCPIGYALREDQKMCKDLD 2296
Y EC C G A D +C D
Sbjct: 1335 YTECCCLYGEAWGMDCALCPAQD 1357
Score = 426 bits (1094), Expect = e-118
Identities = 358/1219 (29%), Positives = 493/1219 (40%), Gaps = 250/1219 (20%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQPCRRGFIPNIRTG 272
G CF ++ C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 250 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 303
Query: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
+ CP G ++ CED+DEC+ G C+ G
Sbjct: 304 ---------------------------DGPCPTGFER--VNGSCEDVDECAT-GGRCQHG 333
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQ 387
EC+NT G Y CVCP G++ + S CI Q G CF L +G C+ + +TK
Sbjct: 334 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 393
Query: 388 CCCEP-GRCWGIGTIPEACPVRGSEEYRRLCMDG--------------LPMGGIPGS--- 429
CCC G+ WG G + CP GSE +R +C G P+G P
Sbjct: 394 CCCSRVGKAWGRGC--QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSL 451
Query: 430 -------AGSRPGGTGGNGFAPSGNGNGYG-------PGGTGFIP-IPGGNGFSPGVGGA 474
A SRP GF P+ PG +P IP G P + +
Sbjct: 452 SQPRTLPATSRPSA----GFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPES 505
Query: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-C 533
G +G +C+ + +C GRCI S Y C C+ G++ G C
Sbjct: 506 GPSSG-----------------MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC 548
Query: 534 IDVDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
IDVDEC PC G C N+PGS+ C C GF+ P C+D+DEC + C GRC
Sbjct: 549 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 608
Query: 592 VNTDGSFQCICNAGFELTTDGKNCVDHDECTTT-NMCLNGMCINEDGSFKCICKPGFVLA 650
NT GSF C+C AG++ G +C D DECT + +C G C N GSF+C+C GF
Sbjct: 609 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--- 665
Query: 651 PNGRYCT-DVDEC-QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--------- 699
G C DVDEC Q P C G C N+ GSF C CP G G C D
Sbjct: 666 -RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 724
Query: 700 --THMRSTCYGGIKKGVCVRPFPGAVTKSEC-----------C----CANPDYGFGEPCQ 742
T+ R G + VC F SEC C C N F C+
Sbjct: 725 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF--QCR 782
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSGYE- 800
CP+ + G C+ D++EC+ C +G C N GS+RC+C GY
Sbjct: 783 TCPSGHHLH-RGRCT----------DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 801 PDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESN 859
P C D++ECL +G C NT GS++CTC PGY +C D++EC E +
Sbjct: 832 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 891
Query: 860 PCVNGACRNNLGSFNCECSPGSKLSSTGLICID----SLKGTCWLNIQDSRCEVNINGAT 915
C +G C N GSF C C PG + C+D +G Q RCE +
Sbjct: 892 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ--RCENSPGSYR 949
Query: 916 LKSECCATLGAAWGSPCE----------------RCE-------LDTACPRGLARIKGVT 952
+C A C+ RCE AC G G
Sbjct: 950 CVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 1009
Query: 953 CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
C+DV+EC + C N GSF C C +G GR C+D+ +E E
Sbjct: 1010 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV---------NECET 1060
Query: 1013 IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPR------GAGF-------A 1059
+ V G A C V ++ C P+ E++ + R AG A
Sbjct: 1061 LQGVCGA----ALCENVEGSFLCVCPNSPE----EFDPMTGRCVPPRTSAGTFPGSQPQA 1112
Query: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFAL-----DMEERNCT 1114
VL RP + + P + +GS + C A ++ RN T
Sbjct: 1113 PASPVLPARPPPPPLPRRPSTPR-------QGPVGSGRRECYFDTAAPDACDNILARNVT 1165
Query: 1115 DIDECRISPDLCGSGICVNT-PGSFE------CECFEGY--ESGFMMMKNCMDIDECER- 1164
+ C + GSG + PG+ C GY SG + ++ D+DEC+
Sbjct: 1166 WQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR--DVDECQLF 1223
Query: 1165 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1224
+C+ G CVNT + C C G+ R +C+D +EC+ + C G+CVN +G+Y
Sbjct: 1224 RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYH 1283
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNG--------GCDTQCT----NSEGSY-ECSCSEG 1271
C+C P ++ C + + + G D C+ + + +Y EC C G
Sbjct: 1284 CTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1343
Query: 1272 YALMPDGRSC--ADIDECE 1288
A D C D D+ E
Sbjct: 1344 EAWGMDCALCPAQDSDDFE 1362
Score = 424 bits (1089), Expect = e-118
Identities = 299/929 (32%), Positives = 393/929 (42%), Gaps = 135/929 (14%)
Query: 1287 CENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKG 1346
C+ NP +C G+C + P Y C C GF S CIDV+EC C G CEN+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 1347 SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG--NGI 1404
SF C C G+ C DVDEC CD+ C N PGSF C C G+ +G
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGA 630
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQ 1464
C D+DEC+ C A C N PGS+RC C GF G DVDECA+ C G+
Sbjct: 631 SCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDVDECAQEPPPCGPGR 688
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI-CVFGTCNNLPGMFHCICDDGYEL 1523
C N G++ C C GF CQD+DEC+ C +G C N G F C+C G++
Sbjct: 689 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 748
Query: 1524 DRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLNPTGVGCVDNRVGNCYLK 1582
+ G C D+DEC + + C CVN+PG ++C CP L+ C D V C
Sbjct: 749 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD--VDECSSG 804
Query: 1583 FGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPN 1642
P G NTE C C+ G P G RP
Sbjct: 805 APPCGPHGHCTNTE-----GSFRCSCAPGYR-------------------APSG---RPG 837
Query: 1643 PITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGV 1702
P D++EC E G C+NT GSF C C GY C D+DEC + +
Sbjct: 838 PCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEEDL 892
Query: 1703 CGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMC 1762
C G C NT G++ CICPP + +C+D+ + C P +C
Sbjct: 893 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-----------CRERGP-----ALC 936
Query: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI-PGICAN 1821
++ CE P ++ + PG+ G D+DEC+E P IC
Sbjct: 937 ---------GSQRCENSP----GSYRCVRDCDPGYHAGPE-GTCDDVDECQEYGPEICGA 982
Query: 1822 GVCINQIGSFRCE--CPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
C N GS+RC C G+ C+D+DEC N + C +A C N PGS++C C
Sbjct: 983 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCD 1040
Query: 1880 AGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNG---------------- 1922
G++ + +G CVD NEC + VC LC +++GS+ C+C N
Sbjct: 1041 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1100
Query: 1923 ----FKASQDQTMCMDVDECERHPCGNGTCKNT-----VGSYNCLCYPGFELTHNNDCLD 1973
F SQ Q V P +T VGS CY F+ + C +
Sbjct: 1101 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY--FDTAAPDACDN 1158
Query: 1974 I-------DEC----SSFFGQVCRNGRC-FNEIGSFKCLCNEGYE-LTPDGKNCI--DTN 2018
I EC +G CR +C E ++ LC G L P G + D +
Sbjct: 1159 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVD 1218
Query: 2019 ECVALPGS-CSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCTNT 2075
EC C G C N + C C GY ++ CID +EC ++ C G C NT
Sbjct: 1219 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNT 1278
Query: 2076 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNF-----ENGK---CSVPKA-FNTTKAKC 2126
G + C C P VL + RRC N E G CS P+ T +C
Sbjct: 1279 VGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTEC 1338
Query: 2127 CCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
CC + GE WG C LCP D F+ LC
Sbjct: 1339 CC--LYGEAWGMDCALCPAQDSDDFEALC 1365
Score = 418 bits (1075), Expect = e-116
Identities = 350/1212 (28%), Positives = 480/1212 (39%), Gaps = 267/1212 (22%)
Query: 171 IGTYCGQPVCENG-----CQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMC 225
I + G + E+G CQ + GP RC C+ +R P T+
Sbjct: 494 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC----- 548
Query: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIP 284
+ C + GR CE P + C GF R C DVDEC +P
Sbjct: 549 ---IDVDECRRVPPPCAPGR-----CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 600
Query: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
C G C NT GSF C CPAG++ + C+D+DEC+ PG+C G C N GS+ CV
Sbjct: 601 PPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV 660
Query: 345 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWG-IGTIPE 403
CP G+ GS C + CAQE P C PGRC G+
Sbjct: 661 CPAGF----RGSACEED----------VDECAQEPPP--------CGPGRCDNTAGSFHC 698
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
ACP R G P + A S P T G G+ P
Sbjct: 699 ACPAG-----FRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP---------- 743
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCE-CN 522
GF P G+ + +D C++H C C+ + S++C C
Sbjct: 744 -MGFQPNTAGSEC----------------EDVDECENHL-ACPGQECVNSPGSFQCRTCP 785
Query: 523 MGYKQDANGDCIDVDECTSN--PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQ--ACIDID 577
G+ G C DVDEC+S PC +G C NT GS+ C C G+ R P+ + C D++
Sbjct: 786 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVN 843
Query: 578 ECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDG 637
EC++ +G C+NTDGSF C C G+ G +C+D DEC+ ++C +G+C N DG
Sbjct: 844 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 903
Query: 638 SFKCICKPGFVLAPNGRYCTDVDECQT--PGICMNGHCINSEGSFRC--DCPPGLAVGMD 693
SF+CIC PG P+ C DVDEC+ P +C + C NS GS+RC DC PG G +
Sbjct: 904 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 963
Query: 694 GRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
G C D EC P+ + C+ P S
Sbjct: 964 G-TCDDV-------------------------DECQEYGPEICGAQRCENTP--GSYRCT 995
Query: 754 GLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
C G T G +D++EC A+ +C+NL GS++C C+ GYE GR+C+D+
Sbjct: 996 PACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1055
Query: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC---RN 868
+EC + +C LC N GS+ C CP N E + G C R
Sbjct: 1056 NECETLQGVCGAALCENVEGSFLCVCP---------------NSPEEFDPMTGRCVPPRT 1100
Query: 869 NLGSF-----NCECSP-----------GSKLSSTGLICIDSLKGTCWLN-IQDSRCEVNI 911
+ G+F SP + S+ + S + C+ + C+ +
Sbjct: 1101 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1160
Query: 912 NGATLKSECCATLGAAWGSPC--------ERCELDTACPRG---LARIKGVTC-EDVNEC 959
ECC T+G WGS C E E + CP G LA ++ DV+EC
Sbjct: 1161 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1220
Query: 960 EVF------PGVCPN-------------------------------------GRCVNSKG 976
++F GVC N GRCVN+ G
Sbjct: 1221 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1280
Query: 977 SFHCECPEGLTLDGTGRVC-------LDIRMEQCYLKWDED-ECIHP-VPGKFRMDACCC 1027
S+HC C L LDG+ R C LD + C+ + D C HP + + CCC
Sbjct: 1281 SYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCC 1340
Query: 1028 AVGAAWGTECEECPKPGTKEYETLC----------PRGAGFA-------NRGDVLTGRPF 1070
G AWG +C CP + ++E LC PR GF + G G P+
Sbjct: 1341 LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPY 1400
Query: 1071 YKDINECKAFP-------------GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDID 1117
++ A P YG R + F+ + G E
Sbjct: 1401 GPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFE---DDGGPYGESEAPAPPGP 1457
Query: 1118 ECR---ISPDLCGSGICVNTP---GSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG 1171
R S D S P GS+ E YE + + C +D C
Sbjct: 1458 GTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEE--LEAEECGILDG-------CTN 1508
Query: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINEC---SLSDNLCRNGKCVNMIGTYQCSCN 1228
G CV F C C G+ L +R CVDINEC + LC N +C+N G+++C C
Sbjct: 1509 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICR 1568
Query: 1229 PGYQATPDRQGC 1240
PG+ T C
Sbjct: 1569 PGFAPTHQPHHC 1580
Score = 392 bits (1007), Expect = e-108
Identities = 271/841 (32%), Positives = 363/841 (43%), Gaps = 144/841 (17%)
Query: 1983 QVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI 2042
QVC GRC + + C C+ G+ L+P G CID +EC +P C+PG C+N GSFRC+
Sbjct: 517 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 576
Query: 2043 CPPGYEV--KSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C PG+ ++ C+D++EC P C G C NTPG F C+CP G+ + +G C D
Sbjct: 577 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 636
Query: 2101 QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG-H 2159
+ C++ PG C+ P +F+ +CP G
Sbjct: 637 E--------------------------CTQSPGLCGRGACKNLPG----SFRCVCPAGFR 666
Query: 2160 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
G+ EDV+EC + P C G+C NT GSF C CP G+ G C D DEC+
Sbjct: 667 GSA-----CEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 721
Query: 2220 GNP-CGNGTCTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAFR-CMNTFGSYE 2276
P C G C N GSF+C C GF+P CED++EC +N L C + C+N+ GS++
Sbjct: 722 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 780
Query: 2277 C-TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEG 2335
C TCP G+ L + C D+DEC+ G C G C N G+F C C PG R P G
Sbjct: 781 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGY-RAPSGRP 836
Query: 2336 --CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
C D NEC +G C+N GS+ C C G++ G CLD + C E L
Sbjct: 837 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEEDL-- 892
Query: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELC--------------------PLPGTAQY 2433
CQ + N EC C G G C PG+ +
Sbjct: 893 -CQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 950
Query: 2434 KKICPHGPGYTTDGR--DIDECKVM-PNLCTNGQCINTMGSFRCF--CKVGYTTDISGTS 2488
+ C G +G D+DEC+ P +C +C NT GS+RC C GY G
Sbjct: 951 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-G 1009
Query: 2489 CIDLDEC-SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFL 2546
C D+DEC ++S + +C+N GS+QC C +GY DG+ C D++EC+T Q C L
Sbjct: 1010 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAAL 1069
Query: 2547 CVNTLGGFTCKCPPG---FTQHHTACIDNNEC-----GSQPSLCGAKGICQNTP------ 2592
C N G F C CP F C+ GSQP + + P
Sbjct: 1070 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPR 1129
Query: 2593 ----------GSFSCECQRGFSLDATGLNCEDVDECDG----NHRCQHGCQNILGGYRCG 2638
GS EC + D CD N Q C + G+ G
Sbjct: 1130 RPSTPRQGPVGSGRRECY---------FDTAAPDACDNILARNVTWQECCCTVGEGWGSG 1180
Query: 2639 CP-------------------QGYIQ---HYQWNQCVDENECSNPNACGSASCYNTLGSY 2676
C +GY+ + VDE + C S C NT Y
Sbjct: 1181 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1240
Query: 2677 KCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGC-PPGYYRVGQGHCV 2734
C C +G+ + C D +EC+ + C G C NT G Y C C PP Q CV
Sbjct: 1241 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1300
Query: 2735 S 2735
S
Sbjct: 1301 S 1301
Score = 377 bits (969), Expect = e-104
Identities = 281/866 (32%), Positives = 378/866 (43%), Gaps = 143/866 (16%)
Query: 1896 CLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNTVG 1953
C P VC G C+ Y C C +GF+ S T C+DVDEC R PC G C+N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 1954 SYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
S+ C+C PGF +CLD+DEC C GRC N GSF C+C GY+ P G
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRV-PPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 630
Query: 2013 NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCI-DINECDEDPNICLFGS 2071
+C D +EC PG C G C+NL GSFRC+CP G+ + C D++EC ++P C G
Sbjct: 631 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGR 688
Query: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
C NT G F C CP GF G C D + C++
Sbjct: 689 CDNTAGSFHCACPAGFRSRGPGAPCQDVDE--------------------------CARS 722
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
P CE + E +FQ +CP G + + EDV+EC E+ C +C+N+
Sbjct: 723 PPPCTYGRCE----NTEGSFQCVCPMGFQPNTAGSEC-EDVDEC-ENHLACPGQECVNSP 776
Query: 2192 GSFRCE-CPMGYNLDYTGVRCVDTDECSIGNP-CG-NGTCTNVIGSFECNCNEGFE---- 2244
GSF+C CP G++L + G RC D DECS G P CG +G CTN GSF C+C G+
Sbjct: 777 GSFQCRTCPSGHHL-HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 834
Query: 2245 -PGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL 2302
PGP C D+NEC + C+NT GS+ CTC GY C D+DEC+E
Sbjct: 835 RPGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE- 890
Query: 2303 HDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK-PGICENGRCVNIIGSY 2361
C+S +C N G+F CICPPG PD C+D +ECR + P +C + RC N GSY
Sbjct: 891 DLCQSG--ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 948
Query: 2362 RC--ECNEGFQSSSSGT-----ECLDNRQGLCFAEVLQTI-----CQMASSSRNLVTKSE 2409
RC +C+ G+ + GT EC + +C A+ + C A T
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1008
Query: 2410 CCCD----GGRGWGHQCELCP-LPGTAQYKKICPHGPGYTTDGR---DIDECKVMPN--- 2458
C D R + +C LPG+ Q +C G DGR D++EC+ +
Sbjct: 1009 GCQDVDECRNRSFCGAHAVCQNLPGSFQC--LCDQGYEGARDGRHCVDVNECETLQGVCG 1066
Query: 2459 --LCTNGQ------CINTMGSF-----RCF---CKVGY---------------------- 2480
LC N + C N+ F RC G
Sbjct: 1067 AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPP 1126
Query: 2481 -----TTDISGTSCIDLDEC---SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD 2532
+T G EC + +P C+ I +C C G + G C+
Sbjct: 1127 LPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR- 1182
Query: 2533 LDECQ-TKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNT 2591
+ +C T+ Q LC + G P G D +EC G+C NT
Sbjct: 1183 IQQCPGTETAEYQSLCPHGRGYLA---PSGDLSLRR---DVDECQLFRDQVCKSGVCVNT 1236
Query: 2592 PGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQW 2649
+SC C G+ L C D DEC D C+ G C N +G Y C C +
Sbjct: 1237 APGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ 1296
Query: 2650 NQCVDENECSNPNACGSASCYNTLGS 2675
+CV S + G C+ +G+
Sbjct: 1297 RRCVSNESQSLDDNLG--VCWQEVGA 1320
Score = 372 bits (956), Expect = e-102
Identities = 274/835 (32%), Positives = 375/835 (44%), Gaps = 104/835 (12%)
Query: 1959 CYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2018
C GFE N C D+DEC++ G C++G C N G + C+C +G+ L +CI +
Sbjct: 307 CPTGFERV-NGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 363
Query: 2019 EC---------VALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICL- 2068
V G CS +N+ C C + C +C
Sbjct: 364 VISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC----------QLCPP 412
Query: 2069 FGSCTNTPGGFQCLCP--PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKC 2126
FGS GF+ +CP PG+ S + R ++TR G+ P+ +
Sbjct: 413 FGS-----EGFREICPAGPGYHYSASDLR-YNTRPL--------GQ-EPPRVSLSQPRTL 457
Query: 2127 CCSKMPGEGWGDPCELCPKDD---------EVAFQDLCPYGHGTVPSLHDTREDVNECLE 2177
+ P G+ L P+ + E+ + + T P + ++ C
Sbjct: 458 PATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW---TGPEIPESGPSSGMCQR 514
Query: 2178 SPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFE 2236
+P +C G+CI+ + C C G+ L G RC+D DEC + PC G C N GSF
Sbjct: 515 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 574
Query: 2237 CNCNEGFEPGP-MMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 2294
C C GF GP C D++EC + P C RC NT GS+ C CP GY C+D
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENGR 2353
+DEC + C RG CKNL G+F C+CP G G C D +EC +P C GR
Sbjct: 635 VDECTQSPGLC-GRG-ACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR 688
Query: 2354 CVNIIGSYRCECNEGFQSSSSGTECLDNRQ----------GLC--FAEVLQTICQMASSS 2401
C N GS+ C C GF+S G C D + G C Q +C M
Sbjct: 689 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 748
Query: 2402 RNLVTKSECC--CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR--DIDECKV-M 2456
++ E C+ Q E PG+ Q + CP G + GR D+DEC
Sbjct: 749 NTAGSECEDVDECENHLACPGQ-ECVNSPGSFQC-RTCPSG-HHLHRGRCTDVDECSSGA 805
Query: 2457 PNLCTNGQCINTMGSFRCFCKVGYTTDISGT--SCIDLDECSQSPKPCNY-ICKNTEGSY 2513
P +G C NT GSFRC C GY SG C D++EC + + C NT+GS+
Sbjct: 806 PPCGPHGHCTNTEGSFRCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPHGECLNTDGSF 864
Query: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QHHTACID 2571
C+C GY G +C D+DEC + +C NT G F C CPPG +C+D
Sbjct: 865 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 924
Query: 2572 NNECGSQ-PSLCGAKGICQNTPGSFSC--ECQRGFSLDATGLNCEDVDECD--GNHRC-Q 2625
+EC + P+LCG++ C+N+PGS+ C +C G+ G C+DVDEC G C
Sbjct: 925 VDECRERGPALCGSQR-CENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGA 982
Query: 2626 HGCQNILGGYRC--GCPQGYIQHYQWNQCVDENECSNPNACGS-ASCYNTLGSYKCACPS 2682
C+N G YRC C GY Q C D +EC N + CG+ A C N GS++C C
Sbjct: 983 QRCENTPGSYRCTPACDPGY-QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1041
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCP--PGYYRVGQGHCV 2734
G+ + C DVNEC + + C C N EG +LC CP P + G CV
Sbjct: 1042 GYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1096
Score = 315 bits (806), Expect = 5e-85
Identities = 299/1019 (29%), Positives = 385/1019 (37%), Gaps = 251/1019 (24%)
Query: 29 QPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNV 88
+P+P P PRP P S + PE E G +S + +R Q + GP
Sbjct: 474 EPRPEPRPDPRPGP------ELPLPSIPAWTGPEIPESGP--SSGMCQRNPQ--VCGPGR 523
Query: 89 CGSRFHSYCC---PGWKTLPGGNQCI-------VP------ICRNS-------CGDGFCS 125
C SR Y C G++ P G +CI VP C NS CG GF +
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRA 583
Query: 126 RPNMC-------------TCSSGQISSTCGSKSIQQCSV---RCMNGGTCAD-DHCQCQK 168
P C G+ +T GS + C +G +C D D C
Sbjct: 584 GPRAAECLDVDECHRVPPPCDLGRCENTPGS-FLCVCPAGYQAAPHGASCQDVDECTQSP 642
Query: 169 GYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQ 228
G CG+ C+N G RC C GF G CE D C +
Sbjct: 643 G----LCGRGACKN-------LPGSFRCVCPAGFRGSACEED--VDECAQEPP------- 682
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQ 288
C C T G C CPA GF CQDVDEC P C
Sbjct: 683 ----PCGPGRCDNTAG---SFHC-ACPA-------GFRSRGPGAPCQDVDECARSPPPCT 727
Query: 289 GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFC-VCPR 347
G C NT GSF+C CP G + + +CED+DEC C EC N+ GS+ C CP
Sbjct: 728 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPS 786
Query: 348 GYVTSTDGSRCIDQRTGMCFSGL----VNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPE 403
G+ RC D C SG +G C +C C PG
Sbjct: 787 GH--HLHRGRCTD--VDECSSGAPPCGPHGHCT----NTEGSFRCSCAPG---------- 828
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
YR + RPG P + N G F P
Sbjct: 829 ---------YR--------------APSGRPG--------PCADVNECLEGDFCF---PH 854
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNM 523
G + A A G P G + L+ +D C +LC +G C T S+ C C
Sbjct: 855 GECLNTDGSFACTCAPGYRPGPRGASCLD--VDECSEE-DLCQSGICTNTDGSFECICPP 911
Query: 524 GYKQDAN-GDCIDVDECTSNP---CTNGDCVNTPGSYYC--KCHAGFQRTPTKQACIDID 577
G++ + C+DVDEC C + C N+PGSY C C G+ P + C D+D
Sbjct: 912 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP-EGTCDDVD 970
Query: 578 ECIQNG-VLCKNGRCVNTDGSFQC--ICNAGFELTTDGKNCVDHDECTTTNMC-LNGMCI 633
EC + G +C RC NT GS++C C+ G++ T G C D DEC + C + +C
Sbjct: 971 ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQ 1029
Query: 634 NEDGSFKCICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCP--PGLAV 690
N GSF+C+C G+ A +GR+C DV+EC+T G+C C N EGSF C CP P
Sbjct: 1030 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1089
Query: 691 GMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGA---------------------------- 722
M GR CV + + G + P A
Sbjct: 1090 PMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYF 1148
Query: 723 ---------------VTKSECCCANPDYGFGEPC--QPCPAKNSAEFHGLCSSGVGITVD 765
VT ECCC + G+G C Q CP +AE+ LC G G
Sbjct: 1149 DTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP 1207
Query: 766 G------RDINECALDPD-ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNR 818
RD++EC L D +C +G+C N Y C C++GY CID DEC
Sbjct: 1208 SGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE 1267
Query: 819 LLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECS 878
C+ G C NT GSY CTC P V C NE +S
Sbjct: 1268 PACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQS-------------------- 1306
Query: 879 PGSKLSSTGLICIDSLKGTCWLNI-QDSRC-EVNINGATLKSECCATLGAAWGSPCERC 935
+D G CW + D C ++ +ECC G AWG C C
Sbjct: 1307 ------------LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALC 1353
Score = 310 bits (795), Expect = 1e-83
Identities = 184/517 (35%), Positives = 244/517 (47%), Gaps = 59/517 (11%)
Query: 2257 CAQNPLLCA-FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNL 2315
C +NP +C RC++ Y C C G+ L C D+DEC C C+N
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG--RCENS 569
Query: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSG 2375
G+F C+C PG P C+D +EC P C+ GRC N GS+ C C G+Q++ G
Sbjct: 570 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 629
Query: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK 2435
C D + T+S C GRG C+ LPG+ ++
Sbjct: 630 ASCQDVDE---------------------CTQSPGLC--GRG---ACK--NLPGS--FRC 659
Query: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
+CP G + D+DEC P C G+C NT GSF C C G+ + G C D+DEC
Sbjct: 660 VCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 719
Query: 2496 SQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
++SP PC Y C+NTEGS+QC CP G+ G C+D+DEC+ CVN+ G F
Sbjct: 720 ARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 779
Query: 2555 TCK-CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLN-C 2612
C+ CP G H C D +EC S CG G C NT GSF C C G+ + C
Sbjct: 780 QCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPC 839
Query: 2613 EDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCY 2670
DV+EC +G+ HG C N G + C C GY + C+D +ECS + C S C
Sbjct: 840 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 899
Query: 2671 NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG---CSNTEGGYLC--GCPPGY 2725
NT GS++C CP G ++C DV+EC + P G C N+ G Y C C PGY
Sbjct: 900 NTDGSFECICPPGHRAGPDLASCLDVDEC-RERGPALCGSQRCENSPGSYRCVRDCDPGY 958
Query: 2726 YRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEAC 2762
+ +G C +VDE PE C
Sbjct: 959 HAGPEGTC---------------DDVDECQEYGPEIC 980
Score = 235 bits (599), Expect = 5e-61
Identities = 168/517 (32%), Positives = 229/517 (44%), Gaps = 81/517 (15%)
Query: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----- 2322
C EC P+ LR + C+ A G+HDC+ +C +G +
Sbjct: 252 CFRELRGGECASPLP-GLRTQEVCCRGAG-LAWGVHDCQ----LCSERLGNSERVSAPDG 305
Query: 2323 -CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
CP G R C D +EC T G C++G C N G Y C C +GF SS + C+
Sbjct: 306 PCPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 362
Query: 2382 R-----QGLCFAEVLQTICQMASSSRNLVTKSECCCDG-GRGWGHQCELCPLPGTAQYKK 2435
+G CF + C + RN +TK CCC G+ WG C+LCP G+ +++
Sbjct: 363 HVISEAKGPCFRVLRDGGCSLPIL-RN-ITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 420
Query: 2436 ICPHGPGYTTDGRD----------------IDECKVMPNLCTNGQCINTMGSFRCFCKVG 2479
ICP GPGY D + + + +P T+ + + R +
Sbjct: 421 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLP--ATSRPSAGFLPTHRLEPRPE 478
Query: 2480 YTTD-----------ISGTSCIDLDECSQSPKPCN---YICKNTEGSYQC-SCPRGYV-- 2522
D I + ++ E S C +C G +C S P GY
Sbjct: 479 PRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC----GPGRCISRPSGYTCA 534
Query: 2523 ------LQEDGKTCKDLDECQTKQHNC-QFLCVNTLGGFTCKCPPGFTQHHTA--CIDNN 2573
L G C D+DEC+ C C N+ G F C C PGF A C+D +
Sbjct: 535 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 594
Query: 2574 ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNI 2631
EC P C G C+NTPGSF C C G+ G +C+DVDEC C G C+N+
Sbjct: 595 ECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL 653
Query: 2632 LGGYRCGCPQGYIQHYQWNQC-VDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQF 2689
G +RC CP G ++ + C D +EC+ P CG C NT GS+ CACP+GF
Sbjct: 654 PGSFRCVCPAG----FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 709
Query: 2690 SSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
+ C DV+EC+ S PC YG C NTEG + C CP G+
Sbjct: 710 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 746
Score = 129 bits (324), Expect = 4e-29
Identities = 108/389 (27%), Positives = 152/389 (39%), Gaps = 50/389 (12%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPLPGTAQYKKICPHGPG 2442
G CF E+ C AS L T+ CC G WG H C+LC + P GP
Sbjct: 250 GYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPC 307
Query: 2443 YTTDGR------DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
T R D+DEC C +G+C NT G + C C G+ D S +SCI S
Sbjct: 308 PTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVIS 366
Query: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC 2556
++ PC + ++ CS P + + C + + + CQ GF
Sbjct: 367 EAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--GCQLCPPFGSEGFRE 420
Query: 2557 KCPPGFTQHHTAC---IDNNECGSQP---SLCGAKGI-CQNTPGSFSCECQR-------- 2601
CP G H++A + G +P SL + + + P + R
Sbjct: 421 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 480
Query: 2602 -----GFSLDATGLNC----EDVDECDGNHRCQHG--------CQNILGGYRCGCPQGYI 2644
G L + E + + CQ C + GY C C G+
Sbjct: 481 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 540
Query: 2645 QHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
Q +C+D +EC P C C N+ GS++C C GF ++ C DV+EC
Sbjct: 541 LSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 600
Query: 2704 NPCNYG-CSNTEGGYLCGCPPGYYRVGQG 2731
PC+ G C NT G +LC CP GY G
Sbjct: 601 PPCDLGRCENTPGSFLCVCPAGYQAAPHG 629
Score = 71.6 bits (174), Expect = 1e-11
Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 1262 GSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK 1321
GSY S +E Y + + C +D C N G+C +P + C C+DG+ M
Sbjct: 1482 GSYAGSLAEPYEEL-EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRM 1533
Query: 1322 TCIDVNECD---LNSNICMFGECENTKGSFICHCQLGYS 1357
C+D+NECD S +C+ C NT GSF C C+ G++
Sbjct: 1534 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1572
Score = 67.4 bits (163), Expect = 2e-10
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1491 DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC-----ADPINCVNG 1545
+ +EC + C G C +P F C C DGY LD T C DI+EC A P+ CVN
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL-CVNA 1554
Query: 1546 LCVNTPGRYECNCPPDF 1562
C+NT G + C C P F
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571
Score = 66.2 bits (160), Expect = 4e-10
Identities = 37/96 (38%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 2156 PYGHGTVPSLHDTREDVN--ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVD 2213
P G SL + E++ EC G C+NG+C+ F C C GY LD T + CVD
Sbjct: 1479 PEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1537
Query: 2214 TDECSIGNP----CGNGTCTNVIGSFECNCNEGFEP 2245
+EC C N C N GSF C C GF P
Sbjct: 1538 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP 1573
Score = 65.9 bits (159), Expect = 6e-10
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 616 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ----TPGICMNG 671
++ +EC + C NG C+ F C C G+ L C D++EC +C+N
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
C+N++GSFRC C PG A C R+
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1587
Score = 65.5 bits (158), Expect = 7e-10
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 2015 IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPN---ICLF 2069
++ EC L G C+ G C + F C C GY + C+DINECDE +C+
Sbjct: 1495 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 2070 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C NT G F+C+C PGF + C R
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 65.1 bits (157), Expect = 1e-09
Identities = 33/79 (41%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC---VALPGSCS 2028
L+ +EC G C NGRC F C C +GY L C+D NEC A C
Sbjct: 1495 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 2029 PGTCQNLEGSFRCICPPGY 2047
C N +GSFRCIC PG+
Sbjct: 1553 NARCLNTDGSFRCICRPGF 1571
Score = 64.7 bits (156), Expect = 1e-09
Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
Query: 2449 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQ----SPKPCNY 2504
+ +EC ++ CTNG+C+ F C C GY D++ +C+D++EC + SP N
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2505 ICKNTEGSYQCSCPRGY 2521
C NT+GS++C C G+
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571
Score = 64.3 bits (155), Expect = 2e-09
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query: 2103 FCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWG-DPCELCPK----DDEVAFQD-LCP 2156
+CF G+C+ P T+ CC + G WG C+LC + + V+ D CP
Sbjct: 251 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 308
Query: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
G V + + EDV+EC G C +G+C NT G + C CP G+ LD + C+
Sbjct: 309 TGFERV---NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 364
Query: 2217 CSIGNPCGNGTCTNVIGSFECN 2238
S G C V+ C+
Sbjct: 365 ISE----AKGPCFRVLRDGGCS 382
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 2212 VDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPG-PMMNCEDINEC----AQNPLLCAF 2266
++ +EC I + C NG C V F C C +G+ M C DINEC A +PL
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2267 RCMNTFGSYECTCPIGYALREDQKMC 2292
RC+NT GS+ C C G+A C
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 63.9 bits (154), Expect = 2e-09
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL---LCRG 1171
+ +EC I D C +G CV P F C CF+GY M C+DI+EC+ LC
Sbjct: 1496 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMA-CVDINECDEAEAASPLCVN 1553
Query: 1172 GTCVNTEGSFQCDCPLG-------HELSPSR 1195
C+NT+GSF+C C G H +P+R
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 63.2 bits (152), Expect = 4e-09
Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 1891 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP-----CGN 1945
++ EC I + C++G CV + + C C +G++ + C+D++EC+ C N
Sbjct: 1495 LEAEEC-GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 1946 GTCKNTVGSYNCLCYPGFELTH 1967
C NT GS+ C+C PGF TH
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTH 1575
Score = 62.4 bits (150), Expect = 6e-09
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD--GFTCSDVDECAEN---INL 1459
+C LD C+NG +CV P + C C +G+ D C D++EC E L
Sbjct: 1499 ECGILDGCTNG--------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1550
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
C N +CLN G++RC C GF P C
Sbjct: 1551 CVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1199 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG----CD 1254
++ EC + D C NG+CV + + C C GY+ R C DI+EC +
Sbjct: 1495 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCA 1282
+C N++GS+ C C G+A CA
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHCA 1581
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
Query: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC---SIIPGICETG 332
+ +EC + G C G C+ F CRC G++ T C DI+EC +C
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
C NT GS+ C+C G+ + C R
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 59.3 bits (142), Expect = 5e-08
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC---FAHPGVCGPG 1706
+ +EC L G C G C+ F C C GY L C DI+EC A +C
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
C NT G++ CIC P + + H+C R
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 57.8 bits (138), Expect = 2e-07
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 1933 MDVDECE-RHPCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDEC--SSFFGQVCRNG 1988
++ +EC C NG C + C C+ G+ L C+DI+EC + +C N
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 1989 RCFNEIGSFKCLCNEGYELTPDGKNC 2014
RC N GSF+C+C G+ T +C
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 57.8 bits (138), Expect = 2e-07
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGD---NLCQR 1863
++ +EC + G C NG C+ F C C G+ + + C DI+EC + LC
Sbjct: 1495 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV- 1552
Query: 1864 NADCINSPGSYRCECAAGF 1882
NA C+N+ GS+RC C GF
Sbjct: 1553 NARCLNTDGSFRCICRPGF 1571
Score = 57.8 bits (138), Expect = 2e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 1242 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDEC---ENNPDICDGGQ 1298
+ +EC I++G + +C + C C +GY L +C DI+EC E +C +
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 1299 CTNIPGEYRCLCYDGFMASMDMKTC 1323
C N G +RC+C GF + C
Sbjct: 1556 CLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 2653 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC----SSSKNPCNY 2708
++ EC + C + C + C C G+ D AC D+NEC ++S N
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQGH 2732
C NT+G + C C PG+ Q H
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPH 1578
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 1449 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC----SFQNICVFG 1504
+ +EC ++ C NG+C+ VP + C C G+ +C DI+EC + +CV
Sbjct: 1496 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 1505 TCNNLPGMFHCICDDGY 1521
C N G F CIC G+
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571
Score = 54.7 bits (130), Expect = 1e-06
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 1848 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPN---VC 1903
C +D C+NG C+ P + C C G++L ACVD NEC E +C
Sbjct: 1500 CGILDGCTNGR--------CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1551
Query: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMC 1932
+ C++ GS++CIC GF + C
Sbjct: 1552 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 54.3 bits (129), Expect = 2e-06
Identities = 71/269 (26%), Positives = 96/269 (35%), Gaps = 61/269 (22%)
Query: 29 QPQPP--PPKPPRPQPPPQQVRSAT--AGSEGGFLAPEYREEGAAVA-SRVRRRG---QQ 80
QPQ P P P RP PPP R +T G G Y + A A + R Q+
Sbjct: 1109 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1168
Query: 81 DVLRGPNVCGSRFHSYCCPGWKT------LPGGNQCIVPI-----------CR----NSC 119
GS CPG +T P G + P C+ C
Sbjct: 1169 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1228
Query: 120 GDGFC--SRPN-MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKG----YIG 172
G C + P C CS+G T + C++ CAD+ C+ G +G
Sbjct: 1229 KSGVCVNTAPGYSCYCSNGYYYHT--------QRLECIDNDECADEEPACEGGRCVNTVG 1280
Query: 173 TY---CGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVN-NQMCQGQ 228
+Y C P+ +G Q RC+ + D G C+ +V + +C
Sbjct: 1281 SYHCTCEPPLVLDGSQR--RCV-----------SNESQSLDDNLGVCWQEVGADLVCSHP 1327
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQ 257
T T CC G AWG C +CPAQ
Sbjct: 1328 RLDRQATYTECCCLYGEAWGMDCALCPAQ 1356
Score = 52.8 bits (125), Expect = 5e-06
Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 21/166 (12%)
Query: 90 GSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC 149
G R CC G G + C + R + + C +++ +C + + +C
Sbjct: 267 GLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSC--EDVDEC 324
Query: 150 SVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCER 209
+ GG C C +G G C VC +G + +R +C+ + +
Sbjct: 325 AT----GGRCQHGECANTRG--GYTC---VCPDGF-----LLDSSRSSCISQHVISEAK- 369
Query: 210 DYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
GPCF + + C + + + CC+ +G+AWG C++CP
Sbjct: 370 ----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 411
Score = 52.8 bits (125), Expect = 5e-06
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 1324 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE--IGAHNCDMH 1381
++ EC + C G C F C C GY + C D++EC+ A ++
Sbjct: 1495 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 1382 ASCLNIPGSFKCSCREGW 1399
A CLN GSF+C CR G+
Sbjct: 1554 ARCLNTDGSFRCICRPGF 1571
Score = 52.8 bits (125), Expect = 5e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 2614 DVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSAS 2668
+ +EC C +G C + G+ C C GY CVD NEC A C +A
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 2669 CYNTLGSYKCACPSGFS 2685
C NT GS++C C GF+
Sbjct: 1556 CLNTDGSFRCICRPGFA 1572
Score = 52.4 bits (124), Expect = 7e-06
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 1739 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN-KPCEPCPTPGTADFKTICGNIPGF 1797
+C+R G C + LP T+ +CC G AW C+ C + + P
Sbjct: 251 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 308
Query: 1798 T-FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGF 1839
T F+ G D+DEC G C +G C N G + C CP GF
Sbjct: 309 TGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGF 350
Score = 52.4 bits (124), Expect = 7e-06
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 2570 IDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD----GNHRCQ 2625
++ ECG G C P F+C C G+ LD T + C D++ECD + C
Sbjct: 1495 LEAEECGILDGC--TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 2626 HG-CQNILGGYRCGCPQGYIQHYQWNQC 2652
+ C N G +RC C G+ +Q + C
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 48.9 bits (115), Expect = 7e-05
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 13/113 (11%)
Query: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
GSY + Y E ++ C LD C G C + F C C G
Sbjct: 1482 GSYAGSLAEPYEELEAEE-CGILDGCTNG---------RCVRVPEGFTCRCFDGYRLDMT 1531
Query: 2333 GEGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
CVD NEC +C N RC+N GS+RC C GF + C R
Sbjct: 1532 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1584
Score = 45.1 bits (105), Expect = 0.001
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2490 IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFL--- 2546
++ +EC N C + C C GY L C D++EC +
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2547 -CVNTLGGFTCKCPPGFTQHH 2566
C+NT G F C C PGF H
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTH 1575
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 2233 GSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC 2292
GS+ + E +E C ++ C RC+ + C C GY L + C
Sbjct: 1482 GSYAGSLAEPYEELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMAC 1535
Query: 2293 KDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMA 2328
D++EC E + S C N G+F CIC PG A
Sbjct: 1536 VDINECDEA--EAASPLCVNARCLNTDGSFRCICRPGFA 1572
Score = 43.5 bits (101), Expect = 0.003
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPG---ICANGVCINQIGSFRCECPTGFS 1840
C G+ D+ VDI+EC E +C N C+N GSFRC C GF+
Sbjct: 1520 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1572
Score = 42.4 bits (98), Expect = 0.007
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 2446 DGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
D + DE + LC N +C+NT GSFRC C+ G+
Sbjct: 1537 DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 39.7 bits (91), Expect = 0.044
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 1633 CPGGEGFRPNPITIILEDIDECQELPG---LCQGGNCINTFGSFQCECPQGYYLSEDTRI 1689
C +G+R + + DI+EC E LC C+NT GSF+C C G+ +
Sbjct: 1520 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1579
Query: 1690 C 1690
C
Sbjct: 1580 C 1580
Score = 38.1 bits (87), Expect = 0.13
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 1532 DIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
+ +EC C NG CV P + C C ++L+ T + CVD
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1537
Score = 35.0 bits (79), Expect = 1.1
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 179 VCENGCQNGGRCIGPNRCACVYGFTGPQCE 208
+C C NGG C+ P+RC C F G C+
Sbjct: 115 LCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 144
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 524 bits (1350), Expect = e-148
Identities = 369/1186 (31%), Positives = 490/1186 (41%), Gaps = 172/1186 (14%)
Query: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFG-EPCQPCPAK--NSAEFH---GLCSSG 759
C+ ++ G C P PG T+ E CC +G CQ C + NS G C +G
Sbjct: 289 CFRELRGGECASPLPGLRTQ-EVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTG 347
Query: 760 VGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVN 817
V+G D++ECA C +G C N RG Y C C G+ D+S +C I + +++
Sbjct: 348 FE-RVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC--ISQHVIS 403
Query: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFN-CE 876
G C C+ P + C + + C + G C
Sbjct: 404 EA---KGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICP 460
Query: 877 CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE 936
PG S++ D T L + R ++ TL + + G E
Sbjct: 461 AGPGYHYSAS-----DLRYNTRPLGQEPPRVSLS-QPRTLPATSRPSAGFLPTHRLEPRP 514
Query: 937 LDTACPRG-----LARIKGVTCEDVNE-------CEVFPGVCPNGRCVNSKGSFHCECPE 984
PR L I T ++ E C+ P VC GRC++ + C C
Sbjct: 515 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 574
Query: 985 GLTLDGTGRVCLDIRMEQCYLKWDEDEC-----------IHPVPGKFRMDACCCAVGAAW 1033
G L G C+D+ DEC PG FR C C G
Sbjct: 575 GFRLSPQGTRCIDV-----------DECRRVPPPCAPGRCENSPGSFR---CVCGPGFRA 620
Query: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTI 1093
G EC D++EC P C G+C NT
Sbjct: 621 GPRAAEC-------------------------------LDVDECHRVPPPCDLGRCENTP 649
Query: 1094 GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMM 1153
GSF C C +G+ +C D+DEC SP LCG G C N PGSF C C G+
Sbjct: 650 GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE 709
Query: 1154 KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN 1213
D+DEC + P C G C NT GSF C CP G C D++EC+ S C
Sbjct: 710 ----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY 765
Query: 1214 GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGY 1272
G+C N G++QC C G+Q C D+DEC +C NS GS++C +C G+
Sbjct: 766 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGH 825
Query: 1273 ALMPDGRSCADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMK-TCIDVNECD 1330
L GR C D+DEC + C G CTN G +RC C G+ A C DVNEC
Sbjct: 826 HLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC- 882
Query: 1331 LNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
L + C GEC NT GSF C C GY C DVDEC + C N G
Sbjct: 883 LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS--EEDLCQSGICTNTDG 940
Query: 1390 SFKCSCREGWIGNG--IKCIDLDECSNGTHQCSINAQCVNTPGSYRCA--CSEGF-TGDG 1444
SF+C C G C+D+DEC + +C N+PGSYRC C G+ G
Sbjct: 941 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 1000
Query: 1445 FTCSDVDECAE-NINLCENGQCLNVPGAYRCE--CEMGFTPASDSRSCQDIDECSFQNIC 1501
TC DVDEC E +C +C N PG+YRC C+ G+ P CQD+DEC ++ C
Sbjct: 1001 GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFC 1059
Query: 1502 -VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN-CVNGLCVNTPGRYECNCP 1559
C NLPG F C+CD GYE R G +C D++EC C LC N G + C CP
Sbjct: 1060 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Query: 1560 --PDFQLNPTGVGCVDNRVGNCYL-----------------------------KFGPRGD 1588
P+ + +P CV R + GP G
Sbjct: 1120 NSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1178
Query: 1589 GSL----------SCNTEIGVGVSRSSCCCSLGKAWGNPC--ETCPPVNSTEYYTLCPGG 1636
G +C+ + V+ CCC++G+ WG+ C + CP + EY +LCP G
Sbjct: 1179 GRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG 1238
Query: 1637 EGF-RPNPITIILEDIDECQELPG-LCQGGNCINTFGSFQCECPQGYYLSEDTRICEDID 1694
G+ P+ + D+DECQ +C+ G C+NT + C C GYY C D D
Sbjct: 1239 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1298
Query: 1695 ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC-------MDMRKSFCYRSYNG- 1746
EC C G C NT+G+Y C C P + C +D C++
Sbjct: 1299 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1358
Query: 1747 TTCEN-ELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
C + L T CCC Y G+AW C CP + DF+ +C
Sbjct: 1359 LVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALC 1402
Score = 491 bits (1264), Expect = e-138
Identities = 338/1034 (32%), Positives = 471/1034 (45%), Gaps = 139/1034 (13%)
Query: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
CP G+ + CED+DEC A G C G C NT G YTC+CP ++ + +C+
Sbjct: 344 CPTGFERVNGS--CEDVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 400
Query: 1737 -----KSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
K C+R C + N+TK++CCC+ VGKAW + C+ CP G+ F+ IC
Sbjct: 401 VISEAKGPCFRVLRDGGCSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREIC 459
Query: 1792 GNIPGFTFDIHTGK-----------AVDIDECKEIPGIC---ANGVCINQIGSFRCECPT 1837
PG+ + + V + + + +P A + +++ P
Sbjct: 460 PAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 519
Query: 1838 GFSYNDLLLVC------EDIDECSNGDNLCQRNAD------CINSPGSYRCECAAGFKLS 1885
+L L +I E +CQRN CI+ P Y C C +GF+LS
Sbjct: 520 PRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 579
Query: 1886 PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HP 1942
P G C+D +EC +P C+ G C + GS++C+C GF+A C+DVDEC R P
Sbjct: 580 PQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 639
Query: 1943 CGNGTCKNTVGSYNCLCYPGFELT-HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLC 2001
C G C+NT GS+ C+C G++ H C D+DEC+ G +C G C N GSF+C+C
Sbjct: 640 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVC 698
Query: 2002 NEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
G+ G C D +EC P C PG C N GSF C CP G+ + C D++
Sbjct: 699 PAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 754
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ---------SFCFTNFE 2109
EC P C +G C NT G FQC+CP GF + G C D + C +
Sbjct: 755 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPG 814
Query: 2110 NGKC-SVPKAFNTTKAKC-----CCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
+ +C + P + + +C C S P G C + E +F+ C G+
Sbjct: 815 SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT----NTEGSFRCSCAPGYRAPS 870
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
DVNECLE +G+C+NTDGSF C C GY G C+D DECS + C
Sbjct: 871 GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC 930
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQ-NPLLC-AFRCMNTFGSYECT-- 2278
+G CTN GSFEC C G GP + +C D++EC + P LC + RC N+ GSY C
Sbjct: 931 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 990
Query: 2279 CPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFMC--ICPPGMARRPDGEG 2335
C GY + C D+DEC E G C ++ C+N G++ C C PG P G G
Sbjct: 991 CDPGYH-AGPEGTCDDVDECQEYGPEICGAQ--RCENTPGSYRCTPACDPGYQPTPGG-G 1046
Query: 2336 CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC 2395
C D +ECR + + C N+ GS++C C++G++ + G C+D + E LQ +C
Sbjct: 1047 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE----CETLQGVC 1102
Query: 2396 QMASSSRNLVTKSECCCDG---------GRGWGHQCELCPLPGT---AQYKKICPHGP-- 2441
A+ N+ C C GR + PG+ A + P P
Sbjct: 1103 G-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPP 1161
Query: 2442 ------------GYTTDGRDIDEC---KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
G GR EC P+ C N N C C VG + G
Sbjct: 1162 PPLPRRPSTPRQGPVGSGR--RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWG 1215
Query: 2487 TSCIDLDECSQSPKPCNYICKNTE-GSYQCSCP--RGYVLQE-DGKTCKDLDECQT-KQH 2541
+ C Q C TE YQ CP RGY+ D +D+DECQ +
Sbjct: 1216 SGC----RIQQ--------CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1263
Query: 2542 NCQF-LCVNTLGGFTCKCPPGFTQH--HTACIDNNECGSQPSLCGAKGICQNTPGSFSCE 2598
C+ +CVNT G++C C G+ H CIDN+EC + C G C NT GS+ C
Sbjct: 1264 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCT 1322
Query: 2599 CQRGFSLDATGLNC 2612
C+ LD + C
Sbjct: 1323 CEPPLVLDGSQRRC 1336
Score = 472 bits (1214), Expect = e-132
Identities = 368/1217 (30%), Positives = 501/1217 (41%), Gaps = 201/1217 (16%)
Query: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
C G G + D C+E + N + ++ P C GF + S C+D+DEC
Sbjct: 311 CCRG-AGLAWGVHDCQLCSERLG---NSERVSAPDG---PCPTGFERVNGS--CEDVDEC 361
Query: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYE 1555
+ C G C N G + C+C DG+ LD + +C I+ G C
Sbjct: 362 ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS----QHVISEAKGPCFRVLRDGG 417
Query: 1556 CNCPPDFQLNPTGVGCVDNRVGNCYLK-------FGPRGDGSLSCNTEIGVGVSRSSCC- 1607
C+ P N T C +RVG + + FG G + C G S S
Sbjct: 418 CSLP--ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI-CPAGPGYHYSASDLRY 474
Query: 1608 -----------CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF---RPNPITIILE---- 1649
SL + P + P + L P E RP P +
Sbjct: 475 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 534
Query: 1650 ---DIDE-------CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
+I E CQ P +C G CI+ + C C G+ LS C D+DEC
Sbjct: 535 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 594
Query: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
P C PG C N+ G++ C+C P + C+D+ + C+R
Sbjct: 595 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CHR---------------VP 637
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1819
C ++G+ N TPG+ F +C G+ H D+DEC + PG+C
Sbjct: 638 PPC----DLGRCEN-------TPGS--FLCVCP--AGYQAAPHGASCQDVDECTQSPGLC 682
Query: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVC-EDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
G C N GSFRC CP GF + C ED+DEC+ C C N+ GS+ C C
Sbjct: 683 GRGACKNLPGSFRCVCPAGFRGS----ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCAC 737
Query: 1879 AAGFK-LSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDE 1937
AGF+ P C D +EC P C++G C + +GS+QC+C GF+ + + C DVDE
Sbjct: 738 PAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE 797
Query: 1938 CERH-PCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGS 1996
CE H C C N+ GS+ C P H C D+DECSS +G C N GS
Sbjct: 798 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 857
Query: 1997 FKCLCNEGYELTPDGK--NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE--VKSE 2052
F+C C GY P G+ C D NEC+ G C N +GSF C C PGY +
Sbjct: 858 FRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 916
Query: 2053 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGK 2112
+C+D++EC E+ ++C G CTNT G F+C+CPPG + C D + E G
Sbjct: 917 SCLDVDECSEE-DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDEC-----RERG- 969
Query: 2113 CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
P + + C PG C +D C G+ P T +DV
Sbjct: 970 ---PALCGSQR----CENSPGS------YRCVRD--------CDPGYHAGP--EGTCDDV 1006
Query: 2173 NECLE-SPGICSNGQCINTDGSFRC--ECPMGYNLDYTGVRCVDTDECSIGNPCG-NGTC 2228
+EC E P IC +C NT GS+RC C GY G C D DEC + CG + C
Sbjct: 1007 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVC 1065
Query: 2229 TNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLC-AFRCMNTFGSYECTCPIGYALR 2286
N+ GSF+C C++G+E +C D+NEC +C A C N GS+ C CP
Sbjct: 1066 QNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP------ 1119
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICP-----PGMARRPDGEGCVDENE 2341
E R + + GTF P P + RP
Sbjct: 1120 ----------NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP------PPPP 1163
Query: 2342 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 2401
+P G +GS R EC ++ + DN +
Sbjct: 1164 LPRRPSTPRQGP----VGSGRREC----YFDTAAPDACDN-----------------ILA 1198
Query: 2402 RNLVTKSECCCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG------RDIDEC 2453
RN VT ECCC G GWG C + CP TA+Y+ +CPHG GY RD+DEC
Sbjct: 1199 RN-VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1257
Query: 2454 KVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEG 2511
++ +C +G C+NT + C+C GY CID DEC+ C C NT G
Sbjct: 1258 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1317
Query: 2512 SYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCP---PGFTQHHTA 2568
SY C+C VL + C +E Q+ N C P T
Sbjct: 1318 SYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECC 1376
Query: 2569 CIDNNECGSQPSLCGAK 2585
C+ G +LC A+
Sbjct: 1377 CLYGEAWGMDCALCPAQ 1393
Score = 458 bits (1179), Expect = e-128
Identities = 293/923 (31%), Positives = 401/923 (43%), Gaps = 156/923 (16%)
Query: 1453 CAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTCNNLPG 1511
C N +C G+C++ P Y C C+ GF + C D+DEC C G C N PG
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 1512 MFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVG 1570
F C+C G+ C D+DEC P C G C NTPG + C CP +Q P G
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 1571 CVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYY 1630
C D V C G G G+ C+ P +
Sbjct: 669 CQD--VDECTQSPGLCGRGA---------------------------CKNLPG----SFR 695
Query: 1631 TLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
+CP G FR + ED+DEC + P C G C NT GSF C CP G+ C
Sbjct: 696 CVCPAG--FRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 750
Query: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
+D+DEC P C G C NT G++ C+CP + G C D+ + CE
Sbjct: 751 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE-----------CE 799
Query: 1751 NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDID 1810
N L C V + C CP+ +H G+ D+D
Sbjct: 800 NHLA-------CPGQECVNSPGSFQCRTCPSG----------------HHLHRGRCTDVD 836
Query: 1811 ECKEIPGICA-NGVCINQIGSFRCECPTGF-SYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
EC C +G C N GSFRC C G+ + + C D++EC GD C + +C+
Sbjct: 837 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD-FCFPHGECL 895
Query: 1869 NSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQ 1927
N+ GS+ C CA G++ P GA C+D +EC E ++C G+C + GS++CIC G +A
Sbjct: 896 NTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGP 954
Query: 1928 DQTMCMDVDEC-ERHP--CGNGTCKNTVGSYNCL--CYPGFELTHNNDCLDIDECSSFFG 1982
D C+DVDEC ER P CG+ C+N+ GSY C+ C PG+ C D+DEC +
Sbjct: 955 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 1014
Query: 1983 QVCRNGRCFNEIGSFKCL--CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
++C RC N GS++C C+ GY+ TP G C D +EC + CQNL GSF+
Sbjct: 1015 EICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQ 1073
Query: 2041 CICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGF----------------QCL 2082
C+C GYE + +C+D+NEC+ +C C N G F +C+
Sbjct: 1074 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1133
Query: 2083 CPPGFVLSDNG---------------------RRCFDTRQS--------FCFTNFENGKC 2113
P + G RR RQ F C
Sbjct: 1134 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1193
Query: 2114 SVPKAFNTTKAKCCCSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGTVPSLHDT--R 2169
A N T +CCC+ GEGWG C + CP + +Q LCP+G G + D R
Sbjct: 1194 DNILARNVTWQECCCTV--GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1251
Query: 2170 EDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2227
DV+EC L +C +G C+NT + C C GY + C+D DEC+ P C G
Sbjct: 1252 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1311
Query: 2228 CTNVIGSFECNCNEGFE-PGPMMNC---------EDINECAQN---PLLCAFRCMNTFGS 2274
C N +GS+ C C G C +++ C Q L+C+ ++ +
Sbjct: 1312 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQAT 1371
Query: 2275 Y-ECTCPIGYALREDQKMCKDLD 2296
Y EC C G A D +C D
Sbjct: 1372 YTECCCLYGEAWGMDCALCPAQD 1394
Score = 426 bits (1094), Expect = e-118
Identities = 358/1219 (29%), Positives = 493/1219 (40%), Gaps = 250/1219 (20%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQPCRRGFIPNIRTG 272
G CF ++ C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 287 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 340
Query: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
+ CP G ++ CED+DEC+ G C+ G
Sbjct: 341 ---------------------------DGPCPTGFER--VNGSCEDVDECAT-GGRCQHG 370
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQ 387
EC+NT G Y CVCP G++ + S CI Q G CF L +G C+ + +TK
Sbjct: 371 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 430
Query: 388 CCCEP-GRCWGIGTIPEACPVRGSEEYRRLCMDG--------------LPMGGIPGS--- 429
CCC G+ WG G + CP GSE +R +C G P+G P
Sbjct: 431 CCCSRVGKAWGRGC--QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSL 488
Query: 430 -------AGSRPGGTGGNGFAPSGNGNGYG-------PGGTGFIP-IPGGNGFSPGVGGA 474
A SRP GF P+ PG +P IP G P + +
Sbjct: 489 SQPRTLPATSRPSA----GFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPES 542
Query: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-C 533
G +G +C+ + +C GRCI S Y C C+ G++ G C
Sbjct: 543 GPSSG-----------------MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC 585
Query: 534 IDVDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
IDVDEC PC G C N+PGS+ C C GF+ P C+D+DEC + C GRC
Sbjct: 586 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 645
Query: 592 VNTDGSFQCICNAGFELTTDGKNCVDHDECTTT-NMCLNGMCINEDGSFKCICKPGFVLA 650
NT GSF C+C AG++ G +C D DECT + +C G C N GSF+C+C GF
Sbjct: 646 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--- 702
Query: 651 PNGRYCT-DVDEC-QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--------- 699
G C DVDEC Q P C G C N+ GSF C CP G G C D
Sbjct: 703 -RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 761
Query: 700 --THMRSTCYGGIKKGVCVRPFPGAVTKSEC-----------C----CANPDYGFGEPCQ 742
T+ R G + VC F SEC C C N F C+
Sbjct: 762 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF--QCR 819
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSGYE- 800
CP+ + G C+ D++EC+ C +G C N GS+RC+C GY
Sbjct: 820 TCPSGHHLH-RGRCT----------DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 801 PDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESN 859
P C D++ECL +G C NT GS++CTC PGY +C D++EC E +
Sbjct: 869 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 928
Query: 860 PCVNGACRNNLGSFNCECSPGSKLSSTGLICID----SLKGTCWLNIQDSRCEVNINGAT 915
C +G C N GSF C C PG + C+D +G Q RCE +
Sbjct: 929 LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ--RCENSPGSYR 986
Query: 916 LKSECCATLGAAWGSPCE----------------RCE-------LDTACPRGLARIKGVT 952
+C A C+ RCE AC G G
Sbjct: 987 CVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 1046
Query: 953 CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
C+DV+EC + C N GSF C C +G GR C+D+ +E E
Sbjct: 1047 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV---------NECET 1097
Query: 1013 IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPR------GAGF-------A 1059
+ V G A C V ++ C P+ E++ + R AG A
Sbjct: 1098 LQGVCGA----ALCENVEGSFLCVCPNSPE----EFDPMTGRCVPPRTSAGTFPGSQPQA 1149
Query: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFAL-----DMEERNCT 1114
VL RP + + P + +GS + C A ++ RN T
Sbjct: 1150 PASPVLPARPPPPPLPRRPSTPR-------QGPVGSGRRECYFDTAAPDACDNILARNVT 1202
Query: 1115 DIDECRISPDLCGSGICVNT-PGSFE------CECFEGY--ESGFMMMKNCMDIDECER- 1164
+ C + GSG + PG+ C GY SG + ++ D+DEC+
Sbjct: 1203 WQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR--DVDECQLF 1260
Query: 1165 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1224
+C+ G CVNT + C C G+ R +C+D +EC+ + C G+CVN +G+Y
Sbjct: 1261 RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYH 1320
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNG--------GCDTQCT----NSEGSY-ECSCSEG 1271
C+C P ++ C + + + G D C+ + + +Y EC C G
Sbjct: 1321 CTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1380
Query: 1272 YALMPDGRSC--ADIDECE 1288
A D C D D+ E
Sbjct: 1381 EAWGMDCALCPAQDSDDFE 1399
Score = 424 bits (1089), Expect = e-118
Identities = 299/929 (32%), Positives = 393/929 (42%), Gaps = 135/929 (14%)
Query: 1287 CENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKG 1346
C+ NP +C G+C + P Y C C GF S CIDV+EC C G CEN+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 1347 SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG--NGI 1404
SF C C G+ C DVDEC CD+ C N PGSF C C G+ +G
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGA 667
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQ 1464
C D+DEC+ C A C N PGS+RC C GF G DVDECA+ C G+
Sbjct: 668 SCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDVDECAQEPPPCGPGR 725
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI-CVFGTCNNLPGMFHCICDDGYEL 1523
C N G++ C C GF CQD+DEC+ C +G C N G F C+C G++
Sbjct: 726 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 785
Query: 1524 DRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLNPTGVGCVDNRVGNCYLK 1582
+ G C D+DEC + + C CVN+PG ++C CP L+ C D V C
Sbjct: 786 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD--VDECSSG 841
Query: 1583 FGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPN 1642
P G NTE C C+ G P G RP
Sbjct: 842 APPCGPHGHCTNTE-----GSFRCSCAPGYR-------------------APSG---RPG 874
Query: 1643 PITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGV 1702
P D++EC E G C+NT GSF C C GY C D+DEC + +
Sbjct: 875 PCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEEDL 929
Query: 1703 CGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMC 1762
C G C NT G++ CICPP + +C+D+ + C P +C
Sbjct: 930 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-----------CRERGP-----ALC 973
Query: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI-PGICAN 1821
++ CE P ++ + PG+ G D+DEC+E P IC
Sbjct: 974 ---------GSQRCENSP----GSYRCVRDCDPGYHAGPE-GTCDDVDECQEYGPEICGA 1019
Query: 1822 GVCINQIGSFRCE--CPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
C N GS+RC C G+ C+D+DEC N + C +A C N PGS++C C
Sbjct: 1020 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAHAVCQNLPGSFQCLCD 1077
Query: 1880 AGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNG---------------- 1922
G++ + +G CVD NEC + VC LC +++GS+ C+C N
Sbjct: 1078 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1137
Query: 1923 ----FKASQDQTMCMDVDECERHPCGNGTCKNT-----VGSYNCLCYPGFELTHNNDCLD 1973
F SQ Q V P +T VGS CY F+ + C +
Sbjct: 1138 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY--FDTAAPDACDN 1195
Query: 1974 I-------DEC----SSFFGQVCRNGRC-FNEIGSFKCLCNEGYE-LTPDGKNCI--DTN 2018
I EC +G CR +C E ++ LC G L P G + D +
Sbjct: 1196 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVD 1255
Query: 2019 ECVALPGS-CSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCTNT 2075
EC C G C N + C C GY ++ CID +EC ++ C G C NT
Sbjct: 1256 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNT 1315
Query: 2076 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNF-----ENGK---CSVPKA-FNTTKAKC 2126
G + C C P VL + RRC N E G CS P+ T +C
Sbjct: 1316 VGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTEC 1375
Query: 2127 CCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
CC + GE WG C LCP D F+ LC
Sbjct: 1376 CC--LYGEAWGMDCALCPAQDSDDFEALC 1402
Score = 418 bits (1075), Expect = e-116
Identities = 350/1212 (28%), Positives = 480/1212 (39%), Gaps = 267/1212 (22%)
Query: 171 IGTYCGQPVCENG-----CQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMC 225
I + G + E+G CQ + GP RC C+ +R P T+
Sbjct: 531 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC----- 585
Query: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIP 284
+ C + GR CE P + C GF R C DVDEC +P
Sbjct: 586 ---IDVDECRRVPPPCAPGR-----CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 637
Query: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
C G C NT GSF C CPAG++ + C+D+DEC+ PG+C G C N GS+ CV
Sbjct: 638 PPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV 697
Query: 345 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWG-IGTIPE 403
CP G+ GS C + CAQE P C PGRC G+
Sbjct: 698 CPAGF----RGSACEED----------VDECAQEPPP--------CGPGRCDNTAGSFHC 735
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
ACP R G P + A S P T G G+ P
Sbjct: 736 ACPAG-----FRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP---------- 780
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCE-CN 522
GF P G+ + +D C++H C C+ + S++C C
Sbjct: 781 -MGFQPNTAGSEC----------------EDVDECENHL-ACPGQECVNSPGSFQCRTCP 822
Query: 523 MGYKQDANGDCIDVDECTSN--PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQ--ACIDID 577
G+ G C DVDEC+S PC +G C NT GS+ C C G+ R P+ + C D++
Sbjct: 823 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVN 880
Query: 578 ECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDG 637
EC++ +G C+NTDGSF C C G+ G +C+D DEC+ ++C +G+C N DG
Sbjct: 881 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 940
Query: 638 SFKCICKPGFVLAPNGRYCTDVDECQT--PGICMNGHCINSEGSFRC--DCPPGLAVGMD 693
SF+CIC PG P+ C DVDEC+ P +C + C NS GS+RC DC PG G +
Sbjct: 941 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 1000
Query: 694 GRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
G C D EC P+ + C+ P S
Sbjct: 1001 G-TCDDV-------------------------DECQEYGPEICGAQRCENTP--GSYRCT 1032
Query: 754 GLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
C G T G +D++EC A+ +C+NL GS++C C+ GYE GR+C+D+
Sbjct: 1033 PACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1092
Query: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC---RN 868
+EC + +C LC N GS+ C CP N E + G C R
Sbjct: 1093 NECETLQGVCGAALCENVEGSFLCVCP---------------NSPEEFDPMTGRCVPPRT 1137
Query: 869 NLGSF-----NCECSP-----------GSKLSSTGLICIDSLKGTCWLN-IQDSRCEVNI 911
+ G+F SP + S+ + S + C+ + C+ +
Sbjct: 1138 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1197
Query: 912 NGATLKSECCATLGAAWGSPC--------ERCELDTACPRG---LARIKGVTC-EDVNEC 959
ECC T+G WGS C E E + CP G LA ++ DV+EC
Sbjct: 1198 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1257
Query: 960 EVF------PGVCPN-------------------------------------GRCVNSKG 976
++F GVC N GRCVN+ G
Sbjct: 1258 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1317
Query: 977 SFHCECPEGLTLDGTGRVC-------LDIRMEQCYLKWDED-ECIHP-VPGKFRMDACCC 1027
S+HC C L LDG+ R C LD + C+ + D C HP + + CCC
Sbjct: 1318 SYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCC 1377
Query: 1028 AVGAAWGTECEECPKPGTKEYETLC----------PRGAGFA-------NRGDVLTGRPF 1070
G AWG +C CP + ++E LC PR GF + G G P+
Sbjct: 1378 LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPY 1437
Query: 1071 YKDINECKAFP-------------GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDID 1117
++ A P YG R + F+ + G E
Sbjct: 1438 GPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFE---DDGGPYGESEAPAPPGP 1494
Query: 1118 ECR---ISPDLCGSGICVNTP---GSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG 1171
R S D S P GS+ E YE + + C +D C
Sbjct: 1495 GTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEE--LEAEECGILDG-------CTN 1545
Query: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINEC---SLSDNLCRNGKCVNMIGTYQCSCN 1228
G CV F C C G+ L +R CVDINEC + LC N +C+N G+++C C
Sbjct: 1546 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICR 1605
Query: 1229 PGYQATPDRQGC 1240
PG+ T C
Sbjct: 1606 PGFAPTHQPHHC 1617
Score = 392 bits (1007), Expect = e-108
Identities = 271/841 (32%), Positives = 363/841 (43%), Gaps = 144/841 (17%)
Query: 1983 QVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI 2042
QVC GRC + + C C+ G+ L+P G CID +EC +P C+PG C+N GSFRC+
Sbjct: 554 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 613
Query: 2043 CPPGYEV--KSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C PG+ ++ C+D++EC P C G C NTPG F C+CP G+ + +G C D
Sbjct: 614 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 673
Query: 2101 QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG-H 2159
+ C++ PG C+ P +F+ +CP G
Sbjct: 674 E--------------------------CTQSPGLCGRGACKNLPG----SFRCVCPAGFR 703
Query: 2160 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
G+ EDV+EC + P C G+C NT GSF C CP G+ G C D DEC+
Sbjct: 704 GSA-----CEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 758
Query: 2220 GNP-CGNGTCTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAFR-CMNTFGSYE 2276
P C G C N GSF+C C GF+P CED++EC +N L C + C+N+ GS++
Sbjct: 759 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 817
Query: 2277 C-TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEG 2335
C TCP G+ L + C D+DEC+ G C G C N G+F C C PG R P G
Sbjct: 818 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGY-RAPSGRP 873
Query: 2336 --CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
C D NEC +G C+N GS+ C C G++ G CLD + C E L
Sbjct: 874 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEEDL-- 929
Query: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELC--------------------PLPGTAQY 2433
CQ + N EC C G G C PG+ +
Sbjct: 930 -CQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 987
Query: 2434 KKICPHGPGYTTDGR--DIDECKVM-PNLCTNGQCINTMGSFRCF--CKVGYTTDISGTS 2488
+ C G +G D+DEC+ P +C +C NT GS+RC C GY G
Sbjct: 988 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-G 1046
Query: 2489 CIDLDEC-SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC-QFL 2546
C D+DEC ++S + +C+N GS+QC C +GY DG+ C D++EC+T Q C L
Sbjct: 1047 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAAL 1106
Query: 2547 CVNTLGGFTCKCPPG---FTQHHTACIDNNEC-----GSQPSLCGAKGICQNTP------ 2592
C N G F C CP F C+ GSQP + + P
Sbjct: 1107 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPR 1166
Query: 2593 ----------GSFSCECQRGFSLDATGLNCEDVDECDG----NHRCQHGCQNILGGYRCG 2638
GS EC + D CD N Q C + G+ G
Sbjct: 1167 RPSTPRQGPVGSGRRECY---------FDTAAPDACDNILARNVTWQECCCTVGEGWGSG 1217
Query: 2639 CP-------------------QGYIQ---HYQWNQCVDENECSNPNACGSASCYNTLGSY 2676
C +GY+ + VDE + C S C NT Y
Sbjct: 1218 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1277
Query: 2677 KCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGC-PPGYYRVGQGHCV 2734
C C +G+ + C D +EC+ + C G C NT G Y C C PP Q CV
Sbjct: 1278 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1337
Query: 2735 S 2735
S
Sbjct: 1338 S 1338
Score = 377 bits (969), Expect = e-104
Identities = 281/866 (32%), Positives = 378/866 (43%), Gaps = 143/866 (16%)
Query: 1896 CLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNTVG 1953
C P VC G C+ Y C C +GF+ S T C+DVDEC R PC G C+N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 1954 SYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
S+ C+C PGF +CLD+DEC C GRC N GSF C+C GY+ P G
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRV-PPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 667
Query: 2013 NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCI-DINECDEDPNICLFGS 2071
+C D +EC PG C G C+NL GSFRC+CP G+ + C D++EC ++P C G
Sbjct: 668 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGR 725
Query: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
C NT G F C CP GF G C D + C++
Sbjct: 726 CDNTAGSFHCACPAGFRSRGPGAPCQDVDE--------------------------CARS 759
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
P CE + E +FQ +CP G + + EDV+EC E+ C +C+N+
Sbjct: 760 PPPCTYGRCE----NTEGSFQCVCPMGFQPNTAGSEC-EDVDEC-ENHLACPGQECVNSP 813
Query: 2192 GSFRCE-CPMGYNLDYTGVRCVDTDECSIGNP-CG-NGTCTNVIGSFECNCNEGFE---- 2244
GSF+C CP G++L + G RC D DECS G P CG +G CTN GSF C+C G+
Sbjct: 814 GSFQCRTCPSGHHL-HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 871
Query: 2245 -PGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL 2302
PGP C D+NEC + C+NT GS+ CTC GY C D+DEC+E
Sbjct: 872 RPGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE- 927
Query: 2303 HDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK-PGICENGRCVNIIGSY 2361
C+S +C N G+F CICPPG PD C+D +ECR + P +C + RC N GSY
Sbjct: 928 DLCQSG--ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 985
Query: 2362 RC--ECNEGFQSSSSGT-----ECLDNRQGLCFAEVLQTI-----CQMASSSRNLVTKSE 2409
RC +C+ G+ + GT EC + +C A+ + C A T
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1045
Query: 2410 CCCD----GGRGWGHQCELCP-LPGTAQYKKICPHGPGYTTDGR---DIDECKVMPN--- 2458
C D R + +C LPG+ Q +C G DGR D++EC+ +
Sbjct: 1046 GCQDVDECRNRSFCGAHAVCQNLPGSFQC--LCDQGYEGARDGRHCVDVNECETLQGVCG 1103
Query: 2459 --LCTNGQ------CINTMGSF-----RCF---CKVGY---------------------- 2480
LC N + C N+ F RC G
Sbjct: 1104 AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPP 1163
Query: 2481 -----TTDISGTSCIDLDEC---SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD 2532
+T G EC + +P C+ I +C C G + G C+
Sbjct: 1164 LPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR- 1219
Query: 2533 LDECQ-TKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNT 2591
+ +C T+ Q LC + G P G D +EC G+C NT
Sbjct: 1220 IQQCPGTETAEYQSLCPHGRGYLA---PSGDLSLRR---DVDECQLFRDQVCKSGVCVNT 1273
Query: 2592 PGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQW 2649
+SC C G+ L C D DEC D C+ G C N +G Y C C +
Sbjct: 1274 APGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ 1333
Query: 2650 NQCVDENECSNPNACGSASCYNTLGS 2675
+CV S + G C+ +G+
Sbjct: 1334 RRCVSNESQSLDDNLG--VCWQEVGA 1357
Score = 372 bits (956), Expect = e-102
Identities = 274/835 (32%), Positives = 375/835 (44%), Gaps = 104/835 (12%)
Query: 1959 CYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2018
C GFE N C D+DEC++ G C++G C N G + C+C +G+ L +CI +
Sbjct: 344 CPTGFERV-NGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 400
Query: 2019 EC---------VALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICL- 2068
V G CS +N+ C C + C +C
Sbjct: 401 VISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC----------QLCPP 449
Query: 2069 FGSCTNTPGGFQCLCP--PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKC 2126
FGS GF+ +CP PG+ S + R ++TR G+ P+ +
Sbjct: 450 FGS-----EGFREICPAGPGYHYSASDLR-YNTRPL--------GQ-EPPRVSLSQPRTL 494
Query: 2127 CCSKMPGEGWGDPCELCPKDD---------EVAFQDLCPYGHGTVPSLHDTREDVNECLE 2177
+ P G+ L P+ + E+ + + T P + ++ C
Sbjct: 495 PATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW---TGPEIPESGPSSGMCQR 551
Query: 2178 SPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFE 2236
+P +C G+CI+ + C C G+ L G RC+D DEC + PC G C N GSF
Sbjct: 552 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 611
Query: 2237 CNCNEGFEPGP-MMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 2294
C C GF GP C D++EC + P C RC NT GS+ C CP GY C+D
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENGR 2353
+DEC + C RG CKNL G+F C+CP G G C D +EC +P C GR
Sbjct: 672 VDECTQSPGLC-GRG-ACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR 725
Query: 2354 CVNIIGSYRCECNEGFQSSSSGTECLDNRQ----------GLC--FAEVLQTICQMASSS 2401
C N GS+ C C GF+S G C D + G C Q +C M
Sbjct: 726 CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 785
Query: 2402 RNLVTKSECC--CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR--DIDECKV-M 2456
++ E C+ Q E PG+ Q + CP G + GR D+DEC
Sbjct: 786 NTAGSECEDVDECENHLACPGQ-ECVNSPGSFQC-RTCPSG-HHLHRGRCTDVDECSSGA 842
Query: 2457 PNLCTNGQCINTMGSFRCFCKVGYTTDISGT--SCIDLDECSQSPKPCNY-ICKNTEGSY 2513
P +G C NT GSFRC C GY SG C D++EC + + C NT+GS+
Sbjct: 843 PPCGPHGHCTNTEGSFRCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPHGECLNTDGSF 901
Query: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QHHTACID 2571
C+C GY G +C D+DEC + +C NT G F C CPPG +C+D
Sbjct: 902 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 961
Query: 2572 NNECGSQ-PSLCGAKGICQNTPGSFSC--ECQRGFSLDATGLNCEDVDECD--GNHRC-Q 2625
+EC + P+LCG++ C+N+PGS+ C +C G+ G C+DVDEC G C
Sbjct: 962 VDECRERGPALCGSQR-CENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGA 1019
Query: 2626 HGCQNILGGYRC--GCPQGYIQHYQWNQCVDENECSNPNACGS-ASCYNTLGSYKCACPS 2682
C+N G YRC C GY Q C D +EC N + CG+ A C N GS++C C
Sbjct: 1020 QRCENTPGSYRCTPACDPGY-QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1078
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCP--PGYYRVGQGHCV 2734
G+ + C DVNEC + + C C N EG +LC CP P + G CV
Sbjct: 1079 GYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1133
Score = 315 bits (806), Expect = 5e-85
Identities = 299/1019 (29%), Positives = 385/1019 (37%), Gaps = 251/1019 (24%)
Query: 29 QPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNV 88
+P+P P PRP P S + PE E G +S + +R Q + GP
Sbjct: 511 EPRPEPRPDPRPGP------ELPLPSIPAWTGPEIPESGP--SSGMCQRNPQ--VCGPGR 560
Query: 89 CGSRFHSYCC---PGWKTLPGGNQCI-------VP------ICRNS-------CGDGFCS 125
C SR Y C G++ P G +CI VP C NS CG GF +
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRA 620
Query: 126 RPNMC-------------TCSSGQISSTCGSKSIQQCSV---RCMNGGTCAD-DHCQCQK 168
P C G+ +T GS + C +G +C D D C
Sbjct: 621 GPRAAECLDVDECHRVPPPCDLGRCENTPGS-FLCVCPAGYQAAPHGASCQDVDECTQSP 679
Query: 169 GYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQ 228
G CG+ C+N G RC C GF G CE D C +
Sbjct: 680 G----LCGRGACKN-------LPGSFRCVCPAGFRGSACEED--VDECAQEPP------- 719
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQ 288
C C T G C CPA GF CQDVDEC P C
Sbjct: 720 ----PCGPGRCDNTAG---SFHC-ACPA-------GFRSRGPGAPCQDVDECARSPPPCT 764
Query: 289 GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFC-VCPR 347
G C NT GSF+C CP G + + +CED+DEC C EC N+ GS+ C CP
Sbjct: 765 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPS 823
Query: 348 GYVTSTDGSRCIDQRTGMCFSGL----VNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPE 403
G+ RC D C SG +G C +C C PG
Sbjct: 824 GH--HLHRGRCTD--VDECSSGAPPCGPHGHCT----NTEGSFRCSCAPG---------- 865
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
YR + RPG P + N G F P
Sbjct: 866 ---------YR--------------APSGRPG--------PCADVNECLEGDFCF---PH 891
Query: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNM 523
G + A A G P G + L+ +D C +LC +G C T S+ C C
Sbjct: 892 GECLNTDGSFACTCAPGYRPGPRGASCLD--VDECSEE-DLCQSGICTNTDGSFECICPP 948
Query: 524 GYKQDAN-GDCIDVDECTSNP---CTNGDCVNTPGSYYC--KCHAGFQRTPTKQACIDID 577
G++ + C+DVDEC C + C N+PGSY C C G+ P + C D+D
Sbjct: 949 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP-EGTCDDVD 1007
Query: 578 ECIQNG-VLCKNGRCVNTDGSFQC--ICNAGFELTTDGKNCVDHDECTTTNMC-LNGMCI 633
EC + G +C RC NT GS++C C+ G++ T G C D DEC + C + +C
Sbjct: 1008 ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQ 1066
Query: 634 NEDGSFKCICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCP--PGLAV 690
N GSF+C+C G+ A +GR+C DV+EC+T G+C C N EGSF C CP P
Sbjct: 1067 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1126
Query: 691 GMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGA---------------------------- 722
M GR CV + + G + P A
Sbjct: 1127 PMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYF 1185
Query: 723 ---------------VTKSECCCANPDYGFGEPC--QPCPAKNSAEFHGLCSSGVGITVD 765
VT ECCC + G+G C Q CP +AE+ LC G G
Sbjct: 1186 DTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP 1244
Query: 766 G------RDINECALDPD-ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNR 818
RD++EC L D +C +G+C N Y C C++GY CID DEC
Sbjct: 1245 SGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE 1304
Query: 819 LLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECS 878
C+ G C NT GSY CTC P V C NE +S
Sbjct: 1305 PACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQS-------------------- 1343
Query: 879 PGSKLSSTGLICIDSLKGTCWLNI-QDSRC-EVNINGATLKSECCATLGAAWGSPCERC 935
+D G CW + D C ++ +ECC G AWG C C
Sbjct: 1344 ------------LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALC 1390
Score = 310 bits (795), Expect = 1e-83
Identities = 184/517 (35%), Positives = 244/517 (47%), Gaps = 59/517 (11%)
Query: 2257 CAQNPLLCA-FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNL 2315
C +NP +C RC++ Y C C G+ L C D+DEC C C+N
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG--RCENS 606
Query: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSG 2375
G+F C+C PG P C+D +EC P C+ GRC N GS+ C C G+Q++ G
Sbjct: 607 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 666
Query: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK 2435
C D + T+S C GRG C+ LPG+ ++
Sbjct: 667 ASCQDVDE---------------------CTQSPGLC--GRG---ACK--NLPGS--FRC 696
Query: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
+CP G + D+DEC P C G+C NT GSF C C G+ + G C D+DEC
Sbjct: 697 VCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 756
Query: 2496 SQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
++SP PC Y C+NTEGS+QC CP G+ G C+D+DEC+ CVN+ G F
Sbjct: 757 ARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 816
Query: 2555 TCK-CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLN-C 2612
C+ CP G H C D +EC S CG G C NT GSF C C G+ + C
Sbjct: 817 QCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPC 876
Query: 2613 EDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCY 2670
DV+EC +G+ HG C N G + C C GY + C+D +ECS + C S C
Sbjct: 877 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 936
Query: 2671 NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG---CSNTEGGYLC--GCPPGY 2725
NT GS++C CP G ++C DV+EC + P G C N+ G Y C C PGY
Sbjct: 937 NTDGSFECICPPGHRAGPDLASCLDVDEC-RERGPALCGSQRCENSPGSYRCVRDCDPGY 995
Query: 2726 YRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEAC 2762
+ +G C +VDE PE C
Sbjct: 996 HAGPEGTC---------------DDVDECQEYGPEIC 1017
Score = 235 bits (599), Expect = 5e-61
Identities = 168/517 (32%), Positives = 229/517 (44%), Gaps = 81/517 (15%)
Query: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----- 2322
C EC P+ LR + C+ A G+HDC+ +C +G +
Sbjct: 289 CFRELRGGECASPLP-GLRTQEVCCRGAG-LAWGVHDCQ----LCSERLGNSERVSAPDG 342
Query: 2323 -CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
CP G R C D +EC T G C++G C N G Y C C +GF SS + C+
Sbjct: 343 PCPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 399
Query: 2382 R-----QGLCFAEVLQTICQMASSSRNLVTKSECCCDG-GRGWGHQCELCPLPGTAQYKK 2435
+G CF + C + RN +TK CCC G+ WG C+LCP G+ +++
Sbjct: 400 HVISEAKGPCFRVLRDGGCSLPIL-RN-ITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 457
Query: 2436 ICPHGPGYTTDGRD----------------IDECKVMPNLCTNGQCINTMGSFRCFCKVG 2479
ICP GPGY D + + + +P T+ + + R +
Sbjct: 458 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLP--ATSRPSAGFLPTHRLEPRPE 515
Query: 2480 YTTD-----------ISGTSCIDLDECSQSPKPCN---YICKNTEGSYQC-SCPRGYV-- 2522
D I + ++ E S C +C G +C S P GY
Sbjct: 516 PRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC----GPGRCISRPSGYTCA 571
Query: 2523 ------LQEDGKTCKDLDECQTKQHNC-QFLCVNTLGGFTCKCPPGFTQHHTA--CIDNN 2573
L G C D+DEC+ C C N+ G F C C PGF A C+D +
Sbjct: 572 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 631
Query: 2574 ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNI 2631
EC P C G C+NTPGSF C C G+ G +C+DVDEC C G C+N+
Sbjct: 632 ECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL 690
Query: 2632 LGGYRCGCPQGYIQHYQWNQC-VDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQF 2689
G +RC CP G ++ + C D +EC+ P CG C NT GS+ CACP+GF
Sbjct: 691 PGSFRCVCPAG----FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 746
Query: 2690 SSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
+ C DV+EC+ S PC YG C NTEG + C CP G+
Sbjct: 747 GAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 783
Score = 129 bits (324), Expect = 4e-29
Identities = 108/389 (27%), Positives = 152/389 (39%), Gaps = 50/389 (12%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPLPGTAQYKKICPHGPG 2442
G CF E+ C AS L T+ CC G WG H C+LC + P GP
Sbjct: 287 GYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPC 344
Query: 2443 YTTDGR------DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
T R D+DEC C +G+C NT G + C C G+ D S +SCI S
Sbjct: 345 PTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVIS 403
Query: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC 2556
++ PC + ++ CS P + + C + + + CQ GF
Sbjct: 404 EAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--GCQLCPPFGSEGFRE 457
Query: 2557 KCPPGFTQHHTAC---IDNNECGSQP---SLCGAKGI-CQNTPGSFSCECQR-------- 2601
CP G H++A + G +P SL + + + P + R
Sbjct: 458 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 517
Query: 2602 -----GFSLDATGLNC----EDVDECDGNHRCQHG--------CQNILGGYRCGCPQGYI 2644
G L + E + + CQ C + GY C C G+
Sbjct: 518 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 577
Query: 2645 QHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
Q +C+D +EC P C C N+ GS++C C GF ++ C DV+EC
Sbjct: 578 LSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 637
Query: 2704 NPCNYG-CSNTEGGYLCGCPPGYYRVGQG 2731
PC+ G C NT G +LC CP GY G
Sbjct: 638 PPCDLGRCENTPGSFLCVCPAGYQAAPHG 666
Score = 71.6 bits (174), Expect = 1e-11
Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 1262 GSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK 1321
GSY S +E Y + + C +D C N G+C +P + C C+DG+ M
Sbjct: 1519 GSYAGSLAEPYEEL-EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRM 1570
Query: 1322 TCIDVNECD---LNSNICMFGECENTKGSFICHCQLGYS 1357
C+D+NECD S +C+ C NT GSF C C+ G++
Sbjct: 1571 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1609
Score = 67.4 bits (163), Expect = 2e-10
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1491 DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC-----ADPINCVNG 1545
+ +EC + C G C +P F C C DGY LD T C DI+EC A P+ CVN
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL-CVNA 1591
Query: 1546 LCVNTPGRYECNCPPDF 1562
C+NT G + C C P F
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608
Score = 66.2 bits (160), Expect = 4e-10
Identities = 37/96 (38%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 2156 PYGHGTVPSLHDTREDVN--ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVD 2213
P G SL + E++ EC G C+NG+C+ F C C GY LD T + CVD
Sbjct: 1516 PEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1574
Query: 2214 TDECSIGNP----CGNGTCTNVIGSFECNCNEGFEP 2245
+EC C N C N GSF C C GF P
Sbjct: 1575 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP 1610
Score = 65.9 bits (159), Expect = 6e-10
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 616 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ----TPGICMNG 671
++ +EC + C NG C+ F C C G+ L C D++EC +C+N
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
C+N++GSFRC C PG A C R+
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1624
Score = 65.5 bits (158), Expect = 7e-10
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 2015 IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPN---ICLF 2069
++ EC L G C+ G C + F C C GY + C+DINECDE +C+
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 2070 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C NT G F+C+C PGF + C R
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 65.1 bits (157), Expect = 1e-09
Identities = 33/79 (41%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC---VALPGSCS 2028
L+ +EC G C NGRC F C C +GY L C+D NEC A C
Sbjct: 1532 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 2029 PGTCQNLEGSFRCICPPGY 2047
C N +GSFRCIC PG+
Sbjct: 1590 NARCLNTDGSFRCICRPGF 1608
Score = 64.7 bits (156), Expect = 1e-09
Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
Query: 2449 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQ----SPKPCNY 2504
+ +EC ++ CTNG+C+ F C C GY D++ +C+D++EC + SP N
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2505 ICKNTEGSYQCSCPRGY 2521
C NT+GS++C C G+
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608
Score = 64.3 bits (155), Expect = 2e-09
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query: 2103 FCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWG-DPCELCPK----DDEVAFQD-LCP 2156
+CF G+C+ P T+ CC + G WG C+LC + + V+ D CP
Sbjct: 288 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 345
Query: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
G V + + EDV+EC G C +G+C NT G + C CP G+ LD + C+
Sbjct: 346 TGFERV---NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 401
Query: 2217 CSIGNPCGNGTCTNVIGSFECN 2238
S G C V+ C+
Sbjct: 402 ISE----AKGPCFRVLRDGGCS 419
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 2212 VDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPG-PMMNCEDINEC----AQNPLLCAF 2266
++ +EC I + C NG C V F C C +G+ M C DINEC A +PL
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2267 RCMNTFGSYECTCPIGYALREDQKMC 2292
RC+NT GS+ C C G+A C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 63.9 bits (154), Expect = 2e-09
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL---LCRG 1171
+ +EC I D C +G CV P F C CF+GY M C+DI+EC+ LC
Sbjct: 1533 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMA-CVDINECDEAEAASPLCVN 1590
Query: 1172 GTCVNTEGSFQCDCPLG-------HELSPSR 1195
C+NT+GSF+C C G H +P+R
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 63.2 bits (152), Expect = 4e-09
Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 1891 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP-----CGN 1945
++ EC I + C++G CV + + C C +G++ + C+D++EC+ C N
Sbjct: 1532 LEAEEC-GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 1946 GTCKNTVGSYNCLCYPGFELTH 1967
C NT GS+ C+C PGF TH
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTH 1612
Score = 62.4 bits (150), Expect = 6e-09
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 1405 KCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD--GFTCSDVDECAEN---INL 1459
+C LD C+NG +CV P + C C +G+ D C D++EC E L
Sbjct: 1536 ECGILDGCTNG--------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1587
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
C N +CLN G++RC C GF P C
Sbjct: 1588 CVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1199 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG----CD 1254
++ EC + D C NG+CV + + C C GY+ R C DI+EC +
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCA 1282
+C N++GS+ C C G+A CA
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHCA 1618
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
Query: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC---SIIPGICETG 332
+ +EC + G C G C+ F CRC G++ T C DI+EC +C
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
C NT GS+ C+C G+ + C R
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 59.3 bits (142), Expect = 5e-08
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC---FAHPGVCGPG 1706
+ +EC L G C G C+ F C C GY L C DI+EC A +C
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
C NT G++ CIC P + + H+C R
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 57.8 bits (138), Expect = 2e-07
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 1933 MDVDECE-RHPCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDEC--SSFFGQVCRNG 1988
++ +EC C NG C + C C+ G+ L C+DI+EC + +C N
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 1989 RCFNEIGSFKCLCNEGYELTPDGKNC 2014
RC N GSF+C+C G+ T +C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 57.8 bits (138), Expect = 2e-07
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGD---NLCQR 1863
++ +EC + G C NG C+ F C C G+ + + C DI+EC + LC
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV- 1589
Query: 1864 NADCINSPGSYRCECAAGF 1882
NA C+N+ GS+RC C GF
Sbjct: 1590 NARCLNTDGSFRCICRPGF 1608
Score = 57.8 bits (138), Expect = 2e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 1242 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDEC---ENNPDICDGGQ 1298
+ +EC I++G + +C + C C +GY L +C DI+EC E +C +
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 1299 CTNIPGEYRCLCYDGFMASMDMKTC 1323
C N G +RC+C GF + C
Sbjct: 1593 CLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 2653 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC----SSSKNPCNY 2708
++ EC + C + C + C C G+ D AC D+NEC ++S N
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQGH 2732
C NT+G + C C PG+ Q H
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPH 1615
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 1449 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC----SFQNICVFG 1504
+ +EC ++ C NG+C+ VP + C C G+ +C DI+EC + +CV
Sbjct: 1533 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 1505 TCNNLPGMFHCICDDGY 1521
C N G F CIC G+
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608
Score = 54.7 bits (130), Expect = 1e-06
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 1848 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPN---VC 1903
C +D C+NG C+ P + C C G++L ACVD NEC E +C
Sbjct: 1537 CGILDGCTNGR--------CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1588
Query: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMC 1932
+ C++ GS++CIC GF + C
Sbjct: 1589 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 54.3 bits (129), Expect = 2e-06
Identities = 71/269 (26%), Positives = 96/269 (35%), Gaps = 61/269 (22%)
Query: 29 QPQPP--PPKPPRPQPPPQQVRSAT--AGSEGGFLAPEYREEGAAVA-SRVRRRG---QQ 80
QPQ P P P RP PPP R +T G G Y + A A + R Q+
Sbjct: 1146 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1205
Query: 81 DVLRGPNVCGSRFHSYCCPGWKT------LPGGNQCIVPI-----------CR----NSC 119
GS CPG +T P G + P C+ C
Sbjct: 1206 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1265
Query: 120 GDGFC--SRPN-MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKG----YIG 172
G C + P C CS+G T + C++ CAD+ C+ G +G
Sbjct: 1266 KSGVCVNTAPGYSCYCSNGYYYHT--------QRLECIDNDECADEEPACEGGRCVNTVG 1317
Query: 173 TY---CGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVN-NQMCQGQ 228
+Y C P+ +G Q RC+ + D G C+ +V + +C
Sbjct: 1318 SYHCTCEPPLVLDGSQR--RCV-----------SNESQSLDDNLGVCWQEVGADLVCSHP 1364
Query: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQ 257
T T CC G AWG C +CPAQ
Sbjct: 1365 RLDRQATYTECCCLYGEAWGMDCALCPAQ 1393
Score = 52.8 bits (125), Expect = 5e-06
Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 21/166 (12%)
Query: 90 GSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC 149
G R CC G G + C + R + + C +++ +C + + +C
Sbjct: 304 GLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSC--EDVDEC 361
Query: 150 SVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCER 209
+ GG C C +G G C VC +G + +R +C+ + +
Sbjct: 362 AT----GGRCQHGECANTRG--GYTC---VCPDGF-----LLDSSRSSCISQHVISEAK- 406
Query: 210 DYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
GPCF + + C + + + CC+ +G+AWG C++CP
Sbjct: 407 ----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 448
Score = 52.8 bits (125), Expect = 5e-06
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 1324 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE--IGAHNCDMH 1381
++ EC + C G C F C C GY + C D++EC+ A ++
Sbjct: 1532 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 1382 ASCLNIPGSFKCSCREGW 1399
A CLN GSF+C CR G+
Sbjct: 1591 ARCLNTDGSFRCICRPGF 1608
Score = 52.8 bits (125), Expect = 5e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 2614 DVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSAS 2668
+ +EC C +G C + G+ C C GY CVD NEC A C +A
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 2669 CYNTLGSYKCACPSGFS 2685
C NT GS++C C GF+
Sbjct: 1593 CLNTDGSFRCICRPGFA 1609
Score = 52.4 bits (124), Expect = 7e-06
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 1739 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN-KPCEPCPTPGTADFKTICGNIPGF 1797
+C+R G C + LP T+ +CC G AW C+ C + + P
Sbjct: 288 YCFRELRGGECASPLPGLRTQEVCC--RGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 345
Query: 1798 T-FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGF 1839
T F+ G D+DEC G C +G C N G + C CP GF
Sbjct: 346 TGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGF 387
Score = 52.4 bits (124), Expect = 7e-06
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 2570 IDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD----GNHRCQ 2625
++ ECG G C P F+C C G+ LD T + C D++ECD + C
Sbjct: 1532 LEAEECGILDGC--TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 2626 HG-CQNILGGYRCGCPQGYIQHYQWNQC 2652
+ C N G +RC C G+ +Q + C
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 48.9 bits (115), Expect = 7e-05
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 13/113 (11%)
Query: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
GSY + Y E ++ C LD C G C + F C C G
Sbjct: 1519 GSYAGSLAEPYEELEAEE-CGILDGCTNG---------RCVRVPEGFTCRCFDGYRLDMT 1568
Query: 2333 GEGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
CVD NEC +C N RC+N GS+RC C GF + C R
Sbjct: 1569 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1621
Score = 45.1 bits (105), Expect = 0.001
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2490 IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFL--- 2546
++ +EC N C + C C GY L C D++EC +
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2547 -CVNTLGGFTCKCPPGFTQHH 2566
C+NT G F C C PGF H
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTH 1612
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 2233 GSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC 2292
GS+ + E +E C ++ C RC+ + C C GY L + C
Sbjct: 1519 GSYAGSLAEPYEELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMAC 1572
Query: 2293 KDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMA 2328
D++EC E + S C N G+F CIC PG A
Sbjct: 1573 VDINECDEA--EAASPLCVNARCLNTDGSFRCICRPGFA 1609
Score = 43.5 bits (101), Expect = 0.003
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPG---ICANGVCINQIGSFRCECPTGFS 1840
C G+ D+ VDI+EC E +C N C+N GSFRC C GF+
Sbjct: 1557 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1609
Score = 42.4 bits (98), Expect = 0.007
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 2446 DGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
D + DE + LC N +C+NT GSFRC C+ G+
Sbjct: 1574 DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 39.7 bits (91), Expect = 0.044
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 1633 CPGGEGFRPNPITIILEDIDECQELPG---LCQGGNCINTFGSFQCECPQGYYLSEDTRI 1689
C +G+R + + DI+EC E LC C+NT GSF+C C G+ +
Sbjct: 1557 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1616
Query: 1690 C 1690
C
Sbjct: 1617 C 1617
Score = 38.1 bits (87), Expect = 0.13
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 1532 DIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
+ +EC C NG CV P + C C ++L+ T + CVD
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1574
Score = 37.4 bits (85), Expect = 0.22
Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 23/131 (17%)
Query: 97 CCPGWKTLPGGNQCIVPICR-NSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMN 155
CCPG + ++CI CR SC C+ P C + S S +Q S+
Sbjct: 55 CCPGQTSRR--SRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQP 112
Query: 156 ------------------GGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCA 197
GG Q+ G +C C NGG C+ P+RC
Sbjct: 113 LTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGK--APVLCPLICHNGGVCVKPDRCL 170
Query: 198 CVYGFTGPQCE 208
C F G C+
Sbjct: 171 CPPDFAGKFCQ 181
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 494 bits (1271), Expect = e-139
Identities = 280/771 (36%), Positives = 389/771 (50%), Gaps = 73/771 (9%)
Query: 1073 DINECKAFPGMCT-YGKCRNTIGSFKCRCNSGFALDME--ERNCTDIDECRISPDLCGSG 1129
D NEC P C G+C N +GS+ C C G+ L + C DI+EC P +C G
Sbjct: 887 DDNECLRDP--CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGG 943
Query: 1130 ICVNTPGSFECECFEGYESGFMMMK-NCMDIDECERNPLLCRGGTCVNTEGSFQC-DCPL 1187
C NT GS+ CEC +GY M+ K +C DI+EC R+P C G CVN+ GS+ C C
Sbjct: 944 QCTNTEGSYHCECDQGY---IMVRKGHCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEE 999
Query: 1188 GHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECM 1247
G+ CVD+NEC L+ +C +GKC N+ G+++CSC GY+ T D +GC D+DEC
Sbjct: 1000 GYRGQSG--SCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA 1056
Query: 1248 IMNGGCDTQ-CTNSEGSYECS-CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGE 1305
C T C N+EGS+ CS C GY + DG +C D+DEC P +C G CTN G
Sbjct: 1057 -SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGS 1114
Query: 1306 YRCL-CYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTG 1364
+ C C G+ S +C DV+EC+ + C+ GEC+NT GS+ C C G+ + GT
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTV- 1173
Query: 1365 CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG--NGIKCIDLDECSNGTHQCSIN 1422
C DV+EC +G +C H CLN GSF C C G++ G C D+DEC+ T C +
Sbjct: 1174 CEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPC-VG 1230
Query: 1423 AQCVNTPGSYRCACSEGF--TGDGFTCSDVDECAENIN-LCENGQCLNVPGAYRCE--CE 1477
CVNT GS+ C C GF + + C D+DEC + + +C +C N PG+YRC C+
Sbjct: 1231 GHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQ 1290
Query: 1478 MGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC 1536
GF A + C DIDEC+ +C G C+N G F C+CD G+E+ +G +C D++EC
Sbjct: 1291 PGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNEC 1349
Query: 1537 ADPIN-CVNGLCVNTPGRYECNCPPDFQLNPTGVG-CVDNRVGNCYLKFGPRGD------ 1588
+ C LC N G + C C D + G C G + P GD
Sbjct: 1350 ELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPT 1409
Query: 1589 ---------GSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
G C++ +G +++ CCC+ G +WG+ C+ CP +S E+ +CP G+G+
Sbjct: 1410 RMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGY 1469
Query: 1640 RPNPIT-----IILEDIDECQEL-PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI 1693
P + D DEC PGLC G C+NT + C C G++ + CED
Sbjct: 1470 IPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDH 1529
Query: 1694 DECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM------------DMRKSFCY 1741
DEC C G C NT G++ C C P CM D+ C+
Sbjct: 1530 DEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICW 1587
Query: 1742 RSYNGTTCENEL-PFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
+ C L T CCC G+AW++ C CP + + +C
Sbjct: 1588 KKVTNDVCSEPLRGHRTTYTECCC--QDGEAWSQQCALCPPRSSEVYAQLC 1636
Score = 464 bits (1193), Expect = e-130
Identities = 379/1340 (28%), Positives = 536/1340 (40%), Gaps = 260/1340 (19%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHP-CEMCPAQPQPCRRGFIPNIRTG 272
G C+ N C L + T+ CC ++G WG C CP +P P I G
Sbjct: 552 GRCYLNTVNGQCANPLLELT-TQEDCCGSVGAFWGVTLCAPCPPRPAS------PVIENG 604
Query: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
+ CP G+K+ T C+DI+EC + G+C+
Sbjct: 605 ---------------------------QLECPQGYKRLNLTH-CQDINECLTL-GLCKDA 635
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQ 387
EC NT GSY C C G + SRC+ + G+C+ L G C L R+TK
Sbjct: 636 ECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQI 695
Query: 388 CCCEP-GRCWGIGTIPEACPVRGSEEYRRLCMDG-----------LPM------------ 423
CCC G+ WG E CP+ G+E +R +C G L M
Sbjct: 696 CCCSRVGKAWGSEC--EKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPP 753
Query: 424 --------GGIPGSAGSRPGGTGGN-----GFAPSGNGNGYGPGGTGFIPIPG---GNGF 467
G +PG A +P + G P + G T P GN
Sbjct: 754 REQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNAT 813
Query: 468 SPGVGGAGVGAGGQGPIITG----LTILNQTIDICKHHA-NLCLNGRCIPTVSSYRCECN 522
+P + G+ + + +T+ ID C A N+C G C+ YRC C+
Sbjct: 814 TPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCS 873
Query: 523 MGYK-QDANGDCIDVDECTSNPCTN-GDCVNTPGSYYCKCHAGFQRTPT--KQACIDIDE 578
GY+ + C D +EC +PC G C+N GSY C C+ G+ + Q C DI+E
Sbjct: 874 PGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINE 933
Query: 579 CIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS 638
C Q GV C G+C NT+GS+ C C+ G+ + G +C D +EC C +G C+N GS
Sbjct: 934 CEQPGV-CSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPGTCPDGRCVNSPGS 991
Query: 639 FKCI-CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVC 697
+ C+ C+ G+ C DV+EC TPG+C +G C N EGSFRC C G V D + C
Sbjct: 992 YTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGC 1049
Query: 698 VDTH---MRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHG 754
D R++C G+C+ G+ S C Y E C + F G
Sbjct: 1050 QDVDECASRASC----PTGLCLNT-EGSFACSAC---ENGYWVNEDGTACEDLDECAFPG 1101
Query: 755 LCSSGVGITVDG--------------------RDINECALDPDICANGICENLRGSYRCN 794
+C SGV G D++EC C G C+N GSY+C
Sbjct: 1102 VCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCL 1161
Query: 795 CNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDIN 854
C G++ A+G C D++EC+ +G C N+ GS+ C C PG+V +C+D++
Sbjct: 1162 CPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVD 1220
Query: 855 ECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICID---------SLKGT--CWLNI 902
EC + +PCV G C N GSFNC C G + S C+D + GT C +
Sbjct: 1221 ECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1280
Query: 903 QDSRCEVNI--------NGATLKSECCA--TLGAAWGSPCERCE--LDTACPRGLA-RIK 949
RC + NG + + CA T+ + G C+ + C +G
Sbjct: 1281 GSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGF-CDNTDGSFRCLCDQGFEISPS 1339
Query: 950 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTL----------DGTGRVCLD-- 997
G C DVNECE+ VC C N +GSF C C L G G +
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399
Query: 998 ---------IRMEQCYLKWDEDECIHPVPGKFRMDA-CCCAVGAAWGTECEECPKPGTKE 1047
RM+ CY V G+ A CCC GA+WG C+ CP + E
Sbjct: 1400 PTGDHAPAPTRMD-CYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE 1458
Query: 1048 YETLCPRGAGFAN-RGDVLTGRPFYKDINECKAF-PGMCTYGKCRNTI------------ 1093
+ +CP G G+ G G+ Y D +EC F PG+C G+C NT+
Sbjct: 1459 FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH 1518
Query: 1094 ----------------------------GSFKCRCNSGFALDMEERNCTD---------- 1115
GSF C C+ LD+ ++ C +
Sbjct: 1519 YDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPD 1578
Query: 1116 ----IDEC--RISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC 1169
+D C +++ D+C + + EC C +G E+ C E LC
Sbjct: 1579 HDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDG-EAWSQQCALCPPRSS-EVYAQLC 1636
Query: 1170 RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNP 1229
+ E G+E P +D S N +G P
Sbjct: 1637 NVAR-IEAEREAGVHFRPGYEYGPGPDDL------HYSIYGPDGAPFYNYLGPEDTVPEP 1689
Query: 1230 GYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECEN 1289
+ T D I+ Q + + Y S E P G +EC
Sbjct: 1690 AFPNTAGHSA----DRTPILES--PLQPSELQPHYVASHPEP----PAGFEGLQAEEC-G 1738
Query: 1290 NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNEC-DLN--SNICMFGECENTKG 1346
+ C+ G+C + Y C C++GF C+DVNEC DLN + +C+ G CENT+G
Sbjct: 1739 ILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEG 1798
Query: 1347 SFICHCQLGYSVKKGTTGCT 1366
S+ CHC GY + G CT
Sbjct: 1799 SYRCHCSPGYVAEAGPPHCT 1818
Score = 440 bits (1131), Expect = e-122
Identities = 318/1027 (30%), Positives = 442/1027 (43%), Gaps = 135/1027 (13%)
Query: 1116 IDECRI-SPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG-GT 1173
ID C + ++CG G CVN P + C C GY+ C D +EC R+P C+G G
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQL-HPSQAYCTDDNECLRDP--CKGKGR 901
Query: 1174 CVNTEGSFQCDCPLGHELSPS--REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 1231
C+N GS+ C C G+ L+ S ++C DINEC +C G+C N G+Y C C+ GY
Sbjct: 902 CINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGY 960
Query: 1232 QATPDRQG-CTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGRSCADIDECEN 1289
R+G C DI+EC D +C NS GSY C +C EGY SC D++EC
Sbjct: 961 IMV--RKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT 1016
Query: 1290 NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFI 1349
P +C G+CTN+ G +RC C G+ + D K C DV+EC ++ C G C NT+GSF
Sbjct: 1017 -PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFA 1074
Query: 1350 CH-CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-CREGWIGN--GIK 1405
C C+ GY V + T C D+DEC C C N GSF C C G+ + G
Sbjct: 1075 CSACENGYWVNEDGTACEDLDECAFPGV-CPSGV-CTNTAGSFSCKDCDGGYRPSPLGDS 1132
Query: 1406 CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT-GDGFTCSDVDECAENINLCENGQ 1464
C D+DEC + C + +C NT GSY+C C +GF +G C DV+EC + +G+
Sbjct: 1133 CEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGE 1191
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELD 1524
CLN G++ C C GF A SCQD+DEC+ + CV G C N G F+C+C+ G++
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPS 1251
Query: 1525 RTGGNCTDIDEC---ADPINCVNGLCVNTPGRYEC--NCPPDFQLNPTGVGCVDNRVGNC 1579
G C DIDEC DP+ C C N+PG Y C C P F + P G C+D + C
Sbjct: 1252 PESGECVDIDECEDYGDPV-CGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCID--IDEC 1307
Query: 1580 YLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
+ + C S G ++T+ C +GF
Sbjct: 1308 ----------------------ANDTMCGSHGFC-----------DNTDGSFRCLCDQGF 1334
Query: 1640 RPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
+P D++EC+ + +C C N GSF C C D++E A
Sbjct: 1335 EISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC------------ASDLEEYDAQ 1382
Query: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNG-TTCENELPFNVT 1758
G C P G + P G H R CY G C + L N T
Sbjct: 1383 EGHCRP----RGAGGQSMSEAP-----TGDHAPAPTRMD-CYSGQKGHAPCSSVLGRNTT 1432
Query: 1759 KRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGF-----TFDIHTGKAVDIDECK 1813
+ CCCT G +W C+ CP+ +A+F IC + G+ + D DEC
Sbjct: 1433 QAECCCTQ--GASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECV 1490
Query: 1814 EI-PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPG 1872
PG+C NG C+N + + C C GF Y+ CED DEC +L N +C+N+ G
Sbjct: 1491 IFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC---QDLACENGECVNTEG 1547
Query: 1873 SYRCECAAGFKLS-PNGACVDRNECLE-IP---------------NVCSHGLCVDLQGSY 1915
S+ C C+ L C++ E +P +VCS L
Sbjct: 1548 SFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYT 1607
Query: 1916 QCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDID 1975
+C C +G SQ +C N PG+E D L
Sbjct: 1608 ECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHY- 1666
Query: 1976 ECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNL 2035
S +G +N +G + + T + L P Q
Sbjct: 1667 ---SIYGP--DGAPFYNYLGPEDTVPEPAFPNTAGH----SADRTPILESPLQPSELQPH 1717
Query: 2036 EGSFRCICPPGYE-VKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGR 2094
+ P G+E +++E C +N C+ G C G+ C C GF L
Sbjct: 1718 YVASHPEPPAGFEGLQAEECGILNGCEN-------GRCVRVREGYTCDCFEGFQLDAAHM 1770
Query: 2095 RCFDTRQ 2101
C D +
Sbjct: 1771 ACVDVNE 1777
Score = 439 bits (1128), Expect = e-122
Identities = 287/815 (35%), Positives = 377/815 (46%), Gaps = 109/815 (13%)
Query: 1771 AW---NKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKE-IPGICANGVCIN 1826
AW N P P G A+ + + T + T ID C +C G C+N
Sbjct: 806 AWVTGNATTPPMPEQGIAEIQE--EQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVN 863
Query: 1827 QIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSP 1886
+RC C G+ + C D +EC C+ CIN GSY C C G+ L+
Sbjct: 864 LPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCFCYPGYTLAT 921
Query: 1887 NGA---CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHP- 1942
+GA C D NEC E P VCS G C + +GSY C C G+ + + C D++EC RHP
Sbjct: 922 SGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGYIMVR-KGHCQDINEC-RHPG 978
Query: 1943 -CGNGTCKNTVGSYNCL-CYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
C +G C N+ GSY CL C G+ + C+D++EC + VC +G+C N GSF+C
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEGYR-GQSGSCVDVNECLT--PGVCAHGKCTNLEGSFRCS 1035
Query: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRC-ICPPGYEVKSEN--CIDI 2057
C +GYE+T D K C D +EC A SC G C N EGSF C C GY V + C D+
Sbjct: 1036 CEQGYEVTSDEKGCQDVDEC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDL 1094
Query: 2058 NECDEDPNICLFGSCTNTPGGFQCL-CPPGFVLSDNGRRCFDTR-----QSFCFTNFENG 2111
+EC P +C G CTNT G F C C G+ S G C D QS C G
Sbjct: 1095 DEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL----GG 1149
Query: 2112 KCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTRED 2171
+C NT + C LCP+ ++A +C ED
Sbjct: 1150 ECK-----NTVGSYQC--------------LCPQGFQLANGTVC--------------ED 1176
Query: 2172 VNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNV 2231
VNEC+ +G+C+N+ GSF C C G+ G C D DEC+ +PC G C N
Sbjct: 1177 VNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNT 1236
Query: 2232 IGSFECNCNEGFEPGPMM-NCEDINECAQ--NPLLCAFRCMNTFGSYECT--CPIGYALR 2286
GSF C C GF+P P C DI+EC +P+ ++C N+ GSY C C G+ +
Sbjct: 1237 EGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMA 1296
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKP 2346
+ C D+DECA C S G C N G+F C+C G P G CVD NEC
Sbjct: 1297 PNGD-CIDIDECANDTM-CGSHG-FCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELML 1353
Query: 2347 GICENGRCVNIIGSYRCEC-----------------NEGFQSSS---SGTECLDNRQGLC 2386
+C C N+ GS+ C C G QS S +G + C
Sbjct: 1354 AVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDC 1413
Query: 2387 FAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY--- 2443
++ + RN T++ECCC G WG C+LCP +A++ +ICP G GY
Sbjct: 1414 YSGQKGHAPCSSVLGRN-TTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPV 1472
Query: 2444 -------TTDGRDIDECKVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
T D DEC + P LC NG+C+NT+ + C C G+ D S C D DEC
Sbjct: 1473 EGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC 1532
Query: 2496 SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTC 2530
Q N C NTEGS+ C C L + C
Sbjct: 1533 -QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRC 1566
Score = 408 bits (1048), Expect = e-113
Identities = 372/1375 (27%), Positives = 522/1375 (37%), Gaps = 331/1375 (24%)
Query: 24 QGTAGQPQPPPPK-PPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDV 82
+GT + QPP P+ PP PQ PP AG+ G ++ ++ VR
Sbjct: 254 EGTLARAQPPAPQSPPAPQSPP-------AGTLSGLSQTHPSQQHVGLSRTVR------- 299
Query: 83 LRGPNVCGSRFHSYCCPGWKTLP--GGNQCIVP--------------------------I 114
L S+ S P L G Q VP I
Sbjct: 300 LHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTI 359
Query: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSKS----------IQQCSVRCMNGGTC-ADDH 163
C+ +C G C+ +C G ++ I C + C+NGG C D
Sbjct: 360 CKQTCARGHCAN----SCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDE 415
Query: 164 CQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACV----YGFTGPQCERDYRTGPCFTQ 219
C C G +C P+ + + GR P FT P + P +
Sbjct: 416 CWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLPLSNQLASVNPSLVK 475
Query: 220 VN-----------NQMCQ---GQLTGIV--CTKTLCCATIGRAWGH-------------- 249
V+ +Q+ Q G +V +T + + GH
Sbjct: 476 VHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWDSNNIPARSGE 535
Query: 250 -PCEMCPAQPQPCRRGFIP----NIRTGACQDVDECQAIPGICQGGNCINTVGSFE---- 300
P + PA P+P RG + N G C + + +C +VG+F
Sbjct: 536 PPRPLPPAAPRP--RGLLGRCYLNTVNGQC-----ANPLLELTTQEDCCGSVGAFWGVTL 588
Query: 301 -CRCPA---------GHKQSETTQKCEDIDECSIIPGICETGECS-----NTVGSYFCVC 345
CP G + K ++ C I G C NT GSY C C
Sbjct: 589 CAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTC 648
Query: 346 PRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQCCC-EPGRCWGIG 399
G + SRC+ + G+C+ L G C L R+TK CCC G+ W G
Sbjct: 649 RPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAW--G 706
Query: 400 TIPEACPVRGSEEYRRLCMDG-----------LPM--------------------GGIPG 428
+ E CP+ G+E +R +C G L M G +PG
Sbjct: 707 SECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPG 766
Query: 429 SAGSRPGGTGGN-----GFAPSGNGNGYGPGGTGFIPIPG---GNGFSPGVGGAGVGAGG 480
A +P + G P + G T P GN +P + G+
Sbjct: 767 PAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQ 826
Query: 481 QGPIITG----LTILNQTIDICKHHA-NLCLNGRCIPTVSSYRCECNMGYK-QDANGDCI 534
+ + +T+ ID C A N+C G C+ YRC C+ GY+ + C
Sbjct: 827 EEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCT 886
Query: 535 DVDECTSNPCT-NGDCVNTPGSYYCKCHAGF--QRTPTKQACIDIDECIQNGVLCKNGRC 591
D +EC +PC G C+N GSY C C+ G+ + Q C DI+EC Q GV C G+C
Sbjct: 887 DDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGV-CSGGQC 945
Query: 592 VNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCI-CKPGFVLA 650
NT+GS+ C C+ G+ + G +C D +EC C +G C+N GS+ C+ C+ G+
Sbjct: 946 TNTEGSYHCECDQGYIMVRKG-HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGY--R 1002
Query: 651 PNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTH---MRSTCY 707
C DV+EC TPG+C +G C N EGSFRC C G V D + C D R++C
Sbjct: 1003 GQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCP 1062
Query: 708 GGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG- 766
G+ C N + F C A C +G + DG
Sbjct: 1063 TGL-------------------CLNTEGSFA-----CSA---------CENGYWVNEDGT 1089
Query: 767 --RDINECALDPDICANGICENLRGSYRC-NCNSGYEPDASGRNCIDIDECLVNRLLCDN 823
D++ECA P +C +G+C N GS+ C +C+ GY P G +C D+DEC + C
Sbjct: 1090 ACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLG 1148
Query: 824 GLCRNTPGSYSCTCPPGYVFRTETETCEDINEC--ESNPCVNGACRNNLGSFNCECSPGS 881
G C+NT GSY C CP G+ T CED+NEC E + +G C N+ GSF C C+PG
Sbjct: 1149 GECKNTVGSYQCLCPQGFQLANGT-VCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF 1207
Query: 882 KLSSTGLICID---------SLKGTCWLNIQDS---RCEVNINGATLKSEC--------- 920
+ G C D + G C +N + S CE + EC
Sbjct: 1208 VSAEGGTSCQDVDECATTDPCVGGHC-VNTEGSFNCLCETGFQPSPESGECVDIDECEDY 1266
Query: 921 ----CATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKG 976
C T RC L C G C D++EC +G C N+ G
Sbjct: 1267 GDPVCGTWKCENSPGSYRCVL--GCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDG 1324
Query: 977 SFHCECPEGLTLDGTGRVCLDI----------------RMEQCYL--------KWDEDE- 1011
SF C C +G + +G C+D+ +E +L ++D E
Sbjct: 1325 SFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG 1384
Query: 1012 ----------------CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRG 1055
P RMD C G C T + E C +G
Sbjct: 1385 HCRPRGAGGQSMSEAPTGDHAPAPTRMD---CYSGQKGHAPCSSVLGRNTTQAECCCTQG 1441
Query: 1056 AGFANRGDVLT--------------------------GRPFYKDINECKAF-PGMCTYGK 1088
A + + D+ G+ Y D +EC F PG+C G+
Sbjct: 1442 ASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGR 1501
Query: 1089 CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDL-CGSGICVNTPGSFECEC 1142
C NT+ + C CN GF D + C D DEC+ DL C +G CVNT GSF C C
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ---DLACENGECVNTEGSFHCFC 1553
Score = 402 bits (1033), Expect = e-111
Identities = 325/1091 (29%), Positives = 458/1091 (41%), Gaps = 207/1091 (18%)
Query: 1608 CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG-GNC 1666
C+ G N C VN + Y C G++ +P D +EC P C+G G C
Sbjct: 848 CAAGAT--NVCGPGTCVNLPDGYR-CVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRC 902
Query: 1667 INTFGSFQCECPQGYYLSED--TRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYM 1724
IN GS+ C C GY L+ T+ C+DI+EC PGVC G C NT G+Y C C Y+
Sbjct: 903 INRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 1725 QVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGT 1784
V GH C D+ + + GT + C + G CE
Sbjct: 962 MVRKGH-CQDINEC----RHPGTCPDGR-----------CVNSPGSYTCLACEE------ 999
Query: 1785 ADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDL 1844
+ +G VD++EC PG+CA+G C N GSFRC C G+
Sbjct: 1000 -------------GYRGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYEVTSD 1045
Query: 1845 LLVCEDIDECSNGDNLCQRNADCINSPGSYRCE-CAAGFKLSPNG-ACVDRNECLEIPNV 1902
C+D+DEC++ + C C+N+ GS+ C C G+ ++ +G AC D +EC P V
Sbjct: 1046 EKGCQDVDECASRAS-CPTGL-CLNTEGSFACSACENGYWVNEDGTACEDLDEC-AFPGV 1102
Query: 1903 CSHGLCVDLQGSYQC-ICHNGFKASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLC 1959
C G+C + GS+ C C G++ S C DVDECE + C G CKNTVGSY CLC
Sbjct: 1103 CPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLC 1162
Query: 1960 YPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE 2019
GF+L + C D++EC +G C N GSF CLC G+ G +C D +E
Sbjct: 1163 PQGFQLANGTVCEDVNECMG-EEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1221
Query: 2020 CVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDE--DPNICLFGSCTNT 2075
C A C G C N EGSF C+C G++ E+ C+DI+EC++ DP +C C N+
Sbjct: 1222 C-ATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP-VCGTWKCENS 1279
Query: 2076 PGGFQCL--CPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPG 2133
PG ++C+ C PGF ++ NG C D + C M G
Sbjct: 1280 PGSYRCVLGCQPGFHMAPNG-DCIDIDE------------------------CANDTMCG 1314
Query: 2134 -EGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDG 2192
G+ D + + +F+ LC G PS D DVNEC +C C N +G
Sbjct: 1315 SHGFCD-------NTDGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEG 1366
Query: 2193 SFRCECPMGYNLDY---------TGVRCVDTDECSIGNPC-------------GNGTCTN 2230
SF C C +Y G E G+ G+ C++
Sbjct: 1367 SFLCLCASDLE-EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSS 1425
Query: 2231 VIG----SFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALR 2286
V+G EC C +G G + + A+ +C S + P+ A
Sbjct: 1426 VLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICP--------SGKGYIPVEGAWT 1477
Query: 2287 EDQKMCKDLDECA-EGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK 2345
Q M D DEC G C + C N + ++C+C PG + C D +EC+
Sbjct: 1478 FGQTMYTDADECVIFGPGLCPNG--RCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDL 1535
Query: 2346 PGICENGRCVNIIGSYRCECN---------EGFQSSSSGTECL---DNRQGLCFAEVLQT 2393
CENG CVN GS+ C C+ + +S+S TE L D +C+ +V
Sbjct: 1536 --ACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND 1593
Query: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC---------------- 2437
+C T +ECCC G W QC LCP + Y ++C
Sbjct: 1594 VCSEPLRGHR-TTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFR 1652
Query: 2438 ---PHGPG--------YTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
+GPG Y DG + NT G++ D +
Sbjct: 1653 PGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNT---------AGHSADRTP 1703
Query: 2487 TSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYV-LQEDGKTCKDLDECQTKQHNCQF 2545
L P +Y+ + E P G+ LQ + C L+ C+ +
Sbjct: 1704 ILESPLQPSELQP---HYVASHPEP------PAGFEGLQ--AEECGILNGCENGR----- 1747
Query: 2546 LCVNTLGGFTCKCPPGF--TQHHTACIDNNECG--SQPSLCGAKGICQNTPGSFSCECQR 2601
CV G+TC C GF H AC+D NEC + P++ G C+NT GS+ C C
Sbjct: 1748 -CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSP 1806
Query: 2602 GFSLDATGLNC 2612
G+ +A +C
Sbjct: 1807 GYVAEAGPPHC 1817
Score = 392 bits (1007), Expect = e-108
Identities = 256/745 (34%), Positives = 342/745 (45%), Gaps = 125/745 (16%)
Query: 1851 IDECSNG-DNLCQRNADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCS-HGL 1907
ID C+ G N+C C+N P YRC C+ G++L P+ A C D NECL P C G
Sbjct: 845 IDRCAAGATNVCGPGT-CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGR 901
Query: 1908 CVDLQGSYQCICHNGFK-ASQDQTM-CMDVDECERHP-CGNGTCKNTVGSYNCLCYPGFE 1964
C++ GSY C C+ G+ A+ T C D++ECE+ C G C NT GSY+C C G+
Sbjct: 902 CINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 1965 LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL-CNEGYELTPDGKNCIDTNECVAL 2023
+ C DI+EC C +GRC N GS+ CL C EGY +C+D NEC+
Sbjct: 962 MVRKGHCQDINECRH--PGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLT- 1016
Query: 2024 PGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCTNTPGGFQC 2081
PG C+ G C NLEGSFRC C GYEV S+ C D++EC + C G C NT G F C
Sbjct: 1017 PGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFAC 1075
Query: 2082 -LCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPC 2140
C G+ ++++G C D + +G C+ + K C GD C
Sbjct: 1076 SACENGYWVNEDGTACEDLDECAFPGVCPSGVCT--NTAGSFSCKDCDGGYRPSPLGDSC 1133
Query: 2141 ELCPKDDEV--------------AFQDLCPYG----HGTVPSLHDTREDVNECLESPGIC 2182
E + ++ ++Q LCP G +GTV EDVNEC+
Sbjct: 1134 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVC------EDVNECMGEEHCA 1187
Query: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEG 2242
+G+C+N+ GSF C C G+ G C D DEC+ +PC G C N GSF C C G
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETG 1247
Query: 2243 FEPGPMMN-CEDINECAQ--NPLLCAFRCMNTFGSYECT--CPIGYALREDQKMCKDLDE 2297
F+P P C DI+EC +P+ ++C N+ GSY C C G+ + + C D+DE
Sbjct: 1248 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDE 1306
Query: 2298 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2357
CA C S G C N G+F C+C G P G CVD NEC +C C N+
Sbjct: 1307 CANDTM-CGSHGF-CDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 2358 IGSYRCEC-----------------NEGFQSSS---SGTECLDNRQGLCFAEVLQTICQM 2397
GS+ C C G QS S +G + C++
Sbjct: 1365 EGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCS 1424
Query: 2398 ASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT----------TDG 2447
+ RN T++ECCC G WG C+LCP +A++ +ICP G GY T
Sbjct: 1425 SVLGRN-TTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMY 1483
Query: 2448 RDIDECKVM-----PN------------------------------------LCTNGQCI 2466
D DEC + PN C NG+C+
Sbjct: 1484 TDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACENGECV 1543
Query: 2467 NTMGSFRCFCKVGYTTDISGTSCID 2491
NT GSF CFC T D+S C++
Sbjct: 1544 NTEGSFHCFCSPPLTLDLSQQRCMN 1568
Score = 391 bits (1005), Expect = e-108
Identities = 262/880 (29%), Positives = 371/880 (42%), Gaps = 168/880 (19%)
Query: 1362 TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--IGNGIKCIDLDECSNGTHQC 1419
T +D C GA N +C+N+P ++C C G+ + C D +EC C
Sbjct: 839 TLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR--DPC 896
Query: 1420 SINAQCVNTPGSYRCACSEGFT----GDGFTCSDVDECAENINLCENGQCLNVPGAYRCE 1475
+C+N GSY C C G+T G C D++EC E +C GQC N G+Y CE
Sbjct: 897 KGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCE 955
Query: 1476 CEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCI-CDDGYELDRTGGNCTDID 1534
C+ G+ CQDI+EC C G C N PG + C+ C++GY G+C D++
Sbjct: 956 CDQGYIMVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVN 1012
Query: 1535 ECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFG-PRG-----D 1588
EC P C +G C N G + C+C +++ GC D V C + P G +
Sbjct: 1013 ECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQD--VDECASRASCPTGLCLNTE 1070
Query: 1589 GSLSCNT-EIGVGVSRSSCCC-SLGK-AWGNPCETCPPVNSTEYYTLCPGGEGFRPNPIT 1645
GS +C+ E G V+ C L + A+ C + N+ ++ G+RP+P+
Sbjct: 1071 GSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLG 1130
Query: 1646 IILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP 1705
ED+DEC++ C GG C NT GS+QC CPQG+ L+ T +CED++EC
Sbjct: 1131 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGT-VCEDVNECMGEEHCAPH 1189
Query: 1706 GTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCEN-ELPFNVTKRMCCC 1764
G C N+ G++ C+C P ++ GG +C D+ + G C N E FN C C
Sbjct: 1190 GECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFN-----CLC 1244
Query: 1765 TYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI-PGICANGV 1823
GF +G+ VDIDEC++ +C
Sbjct: 1245 E-----------------------------TGFQPSPESGECVDIDECEDYGDPVCGTWK 1275
Query: 1824 CINQIGSFRC--ECPTGFSY---NDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
C N GS+RC C GF D C DIDEC+N D +C + C N+ GS+RC C
Sbjct: 1276 CENSPGSYRCVLGCQPGFHMAPNGD----CIDIDECAN-DTMCGSHGFCDNTDGSFRCLC 1330
Query: 1879 AAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK------------- 1924
GF++SP+G CVD NEC + VC LC +++GS+ C+C + +
Sbjct: 1331 DQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRG 1390
Query: 1925 ---------ASQDQTMCMDVDECERHPCGNGTCKNTVG----SYNCLCYPG------FEL 1965
+ D +C G+ C + +G C C G +L
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1450
Query: 1966 THNNDC---------------------------LDIDECSSFFGQVCRNGRCFNEIGSFK 1998
+ D D DEC F +C NGRC N + +
Sbjct: 1451 CPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYV 1510
Query: 1999 CLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPP--GYEVKSENCID 2056
CLCN G+ K C D +EC L +C G C N EGSF C C P ++ + C++
Sbjct: 1511 CLCNPGFHYDASHKKCEDHDECQDL--ACENGECVNTEGSFHCFCSPPLTLDLSQQRCMN 1568
Query: 2057 INECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVP 2116
ED L D+ D C+ N CS P
Sbjct: 1569 STSSTED-------------------------LPDH-----DIHMDICWKKVTNDVCSEP 1598
Query: 2117 -KAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
+ TT +CCC GE W C LCP + LC
Sbjct: 1599 LRGHRTTYTECCC--QDGEAWSQQCALCPPRSSEVYAQLC 1636
Score = 389 bits (999), Expect = e-107
Identities = 306/1066 (28%), Positives = 426/1066 (39%), Gaps = 202/1066 (18%)
Query: 576 IDECIQNGV-LCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCIN 634
ID C +C G CVN ++C+C+ G++L C D +EC G CIN
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 635 EDGSFKCICKPGFVLAPNG--RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGM 692
GS+ C C PG+ LA +G + C D++EC+ PG+C G C N+EGS+ C+C G +
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR 964
Query: 693 DGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEF 752
G C D + G G CV PG+ T C C +
Sbjct: 965 KGH-CQDIN-ECRHPGTCPDGRCVNS-PGSYT----------------CLAC----EEGY 1001
Query: 753 HGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 812
G S V D+NEC L P +CA+G C NL GS+RC+C GYE + + C D+D
Sbjct: 1002 RGQSGSCV-------DVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVD 1053
Query: 813 ECLVNRLLCDNGLCRNTPGSYSCT-CPPGYVFRTETETCEDINECE-SNPCVNGACRNNL 870
EC +R C GLC NT GS++C+ C GY + CED++EC C +G C N
Sbjct: 1054 EC-ASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTA 1112
Query: 871 GSFNC-ECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWG 929
GSF+C +C G + S G C D CE + + L EC T+G+
Sbjct: 1113 GSFSCKDCDGGYRPSPLGDSCEDV-----------DECE-DPQSSCLGGECKNTVGS--- 1157
Query: 930 SPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLD 989
CP+G G CEDVNEC P+G C+NS GSF C C G
Sbjct: 1158 -------YQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSA 1210
Query: 990 GTGRVCLDIRMEQCYLKWDEDECI--HPV--PGKFRMDACCCAVGAAWGTECEECP---- 1041
G C D+ ++C D C+ H V G F C C G E EC
Sbjct: 1211 EGGTSCQDV--DECATT---DPCVGGHCVNTEGSFN---CLCETGFQPSPESGECVDIDE 1262
Query: 1042 ----------------KPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMC- 1084
PG+ C G A GD + DI+EC A MC
Sbjct: 1263 CEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCI-------DIDEC-ANDTMCG 1314
Query: 1085 TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFE 1144
++G C NT GSF+C C+ GF + +C D++EC + +CG+ +C N GSF C C
Sbjct: 1315 SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCAS 1374
Query: 1145 GYESGFMMMKNC------------------------MDIDECERNPLLCRG--------G 1172
E +C MD ++ C
Sbjct: 1375 DLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQA 1434
Query: 1173 TCVNTEGSF---QCD-------------CPLGHELSP-------SREDCVDINECSL-SD 1208
C T+G+ CD CP G P + D +EC +
Sbjct: 1435 ECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGP 1494
Query: 1209 NLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDT-QCTNSEGSYECS 1267
LC NG+C+N + Y C CNPG+ + C D DEC + C+ +C N+EGS+ C
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDL--ACENGECVNTEGSFHCF 1552
Query: 1268 CSEGYAL-------MPDGRSCADIDECENNPDICDGGQCTNIPGE---------YRCLCY 1311
CS L M S D+ + + + DIC ++ E C C
Sbjct: 1553 CSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQ 1612
Query: 1312 DGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC 1371
DG S C ++ + +C E + + + H + GY
Sbjct: 1613 DGEAWSQQCALC-PPRSSEVYAQLCNVARIEAEREAGV-HFRPGY--------------- 1655
Query: 1372 EIGAHNCDMHASCLNIPGS--FKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTP 1429
E G D+H S G+ + E + ++ T Q
Sbjct: 1656 EYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQ 1715
Query: 1430 GSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
Y + E GF +EC +N CENG+C+ V Y C+C GF + +C
Sbjct: 1716 PHYVASHPE--PPAGFEGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAHMAC 1772
Query: 1490 QDIDECSFQN----ICVFGTCNNLPGMFHCICDDGYELDRTGGNCT 1531
D++EC N +CV G C N G + C C GY + +CT
Sbjct: 1773 VDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCT 1818
Score = 365 bits (937), Expect = e-100
Identities = 277/898 (30%), Positives = 375/898 (41%), Gaps = 150/898 (16%)
Query: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLC 2001
PC + + C G++ + C DI+EC + +C++ C N GS+ C C
Sbjct: 591 PCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTL--GLCKDAECVNTRGSYLCTC 648
Query: 2002 NEGYELTPDGKNCIDTNECVALPGSC----SPGTC-----QNLEGSFRCICPPGYEVKSE 2052
G L P C+ L G C PGTC Q + C G S
Sbjct: 649 RPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGS- 707
Query: 2053 NCIDINECDEDPNICLFGSCTNTPG--GFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFEN 2110
EC++ P PG F+ +CP G +G + E
Sbjct: 708 ------ECEKCP----------LPGTEAFREICPAG-----HGYTYASSDIRLSMRKAEE 746
Query: 2111 GKCSVPKAFNTTKAKCCCSKMPG-----------EGWGDPCELCPKDDEVAFQDLCPY-- 2157
+ + P ++ +PG + W + + K D A Q
Sbjct: 747 EELARPPREQGQRSS---GALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTH 803
Query: 2158 ------GHGTVPSLHD------------TREDVNECLESPGI----------CSNGQCIN 2189
G+ T P + + DV L +PGI C G C+N
Sbjct: 804 APAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVN 863
Query: 2190 TDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC-GNGTCTNVIGSFECNCNEGF---EP 2245
+RC C GY L + C D +EC + +PC G G C N +GS+ C C G+
Sbjct: 864 LPDGYRCVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATS 922
Query: 2246 GPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
G C+DINEC Q + +C NT GSY C C GY + + C+D++EC H
Sbjct: 923 GATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR-KGHCQDINECR---HPG 978
Query: 2306 ESRGMMCKNLIGTFMCI-CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCE 2364
C N G++ C+ C G R CVD NEC T PG+C +G+C N+ GS+RC
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCS 1035
Query: 2365 CNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCEL 2424
C +G++ +S C D + A +C L T+ C
Sbjct: 1036 CEQGYEVTSDEKGCQDVDECASRASCPTGLC--------LNTEGSFACSA---------- 1077
Query: 2425 CPLPGTAQYKKICPHGPGYTTDG---RDIDECKVMPNLCTNGQCINTMGSFRC-FCKVGY 2480
C +G DG D+DEC P +C +G C NT GSF C C GY
Sbjct: 1078 ------------CENGYWVNEDGTACEDLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGY 1124
Query: 2481 TTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2539
G SC D+DEC C CKNT GSYQC CP+G+ L +G C+D++EC +
Sbjct: 1125 RPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGE 1183
Query: 2540 QHNCQF-LCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFS 2596
+H C+N+ G F C C PGF + T+C D +EC + G G C NT GSF+
Sbjct: 1184 EHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVG--GHCVNTEGSFN 1241
Query: 2597 CECQRGFSLDATGLNCEDVDECD--GNHRC-QHGCQNILGGYRC--GCPQGYIQHYQWN- 2650
C C+ GF C D+DEC+ G+ C C+N G YRC GC G+ H N
Sbjct: 1242 CLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF--HMAPNG 1299
Query: 2651 QCVDENECSNPNACGS-ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG 2709
C+D +EC+N CGS C NT GS++C C GF C DVNEC C
Sbjct: 1300 DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1359
Query: 2710 -CSNTEGGYLCGCPPGY--YRVGQGHC-VSGMGFNKGQYLSLDTEVDEENALSPEACY 2763
C N EG +LC C Y +GHC G G GQ +S D A + CY
Sbjct: 1360 LCENVEGSFLCLCASDLEEYDAQEGHCRPRGAG---GQSMSEAPTGDHAPAPTRMDCY 1414
Score = 347 bits (891), Expect = 8e-95
Identities = 249/797 (31%), Positives = 341/797 (42%), Gaps = 96/797 (12%)
Query: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC--VALPGSCSPGTCQNLEGSFRCICPP 2045
GRC+ + +C N ELT C V L C P + + + CP
Sbjct: 552 GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 2046 GYE-VKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR---- 2100
GY+ + +C DINEC +C C NT G + C C PG +L + RC +
Sbjct: 611 GYKRLNLTHCQDINEC-LTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM 669
Query: 2101 -QSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGH 2159
Q C+ + G C++P A TK CCCS++ G+ WG CE CP AF+++CP GH
Sbjct: 670 LQGLCYRSLGPGTCTLPLAQRITKQICCCSRV-GKAWGSECEKCPLPGTEAFREICPAGH 728
Query: 2160 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
G + D R + + E + G R + + +R V
Sbjct: 729 GYTYASSDIRLSMRKAEEE----ELARPPREQGQ-RSSGALPGPAERQPLRVVTDTWLEA 783
Query: 2220 G-------NPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF 2272
G + G T + N P P +I E P ++T
Sbjct: 784 GTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTP 843
Query: 2273 GSYEC-----------TC---PIGY--------ALREDQKMCKDLDECAEGLHDCESRGM 2310
G C TC P GY L Q C D +EC C+ +G
Sbjct: 844 GIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR--DPCKGKG- 900
Query: 2311 MCKNLIGTFMCICPPGMARRPDG--EGCVDENECRTKPGICENGRCVNIIGSYRCECNEG 2368
C N +G++ C C PG G + C D NEC +PG+C G+C N GSY CEC++G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 959
Query: 2369 FQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLP 2428
+ G CQ + R+ T C DG +C P
Sbjct: 960 YIMVRKGH------------------CQDINECRHPGT----CPDG------RCVNSPGS 991
Query: 2429 GTAQYKKICPHG-PGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGT 2487
T C G G + D++EC + P +C +G+C N GSFRC C+ GY
Sbjct: 992 YTC---LACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEK 1047
Query: 2488 SCIDLDECSQSPKPCNYICKNTEGSYQCS-CPRGYVLQEDGKTCKDLDECQTKQHNCQFL 2546
C D+DEC+ +C NTEGS+ CS C GY + EDG C+DLDEC +
Sbjct: 1048 GCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGV 1107
Query: 2547 CVNTLGGFTCK-CPPGF--TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGF 2603
C NT G F+CK C G+ + +C D +EC S C G C+NT GS+ C C +GF
Sbjct: 1108 CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGF 1166
Query: 2604 SLDATGLNCEDVDECDGNHRC-QHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNP 2661
L A G CEDV+EC G C HG C N G + C C G++ C D +EC+
Sbjct: 1167 QL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATT 1225
Query: 2662 NACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPC--NYGCSNTEGGYLC 2719
+ C C NT GS+ C C +GF S C D++EC +P + C N+ G Y C
Sbjct: 1226 DPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRC 1285
Query: 2720 --GCPPGYYRVGQGHCV 2734
GC PG++ G C+
Sbjct: 1286 VLGCQPGFHMAPNGDCI 1302
Score = 340 bits (873), Expect = 9e-93
Identities = 261/875 (29%), Positives = 366/875 (41%), Gaps = 156/875 (17%)
Query: 134 SGQISSTCGSKSIQQCSVRCMN---GGTCAD----DHCQCQKGY----IGTYC--GQPVC 180
S + T + I +C+ N GTC + C C GY YC
Sbjct: 833 STDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL 892
Query: 181 ENGCQNGGRCI---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKT 237
+ C+ GRCI G C C G+T T C +N G +G CT T
Sbjct: 893 RDPCKGKGRCINRVGSYSCFCYPGYT---LATSGATQEC-QDINECEQPGVCSGGQCTNT 948
Query: 238 LCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVG 297
+ CE C +G+I +R G CQD++EC+ PG C G C+N+ G
Sbjct: 949 --------EGSYHCE--------CDQGYIM-VRKGHCQDINECRH-PGTCPDGRCVNSPG 990
Query: 298 SFEC-RCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGS 356
S+ C C G++ + C D++EC + PG+C G+C+N GS+ C C +GY ++D
Sbjct: 991 SYTCLACEEGYRGQSGS--CVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEK 1047
Query: 357 RCIDQR---------TGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPV 407
C D TG+C + + C+ CE G + + AC
Sbjct: 1048 GCQDVDECASRASCPTGLCLNTEGSFACS------------ACENG--YWVNEDGTACED 1093
Query: 408 RGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF 467
+ +C P G +AGS G+ PS G+ P
Sbjct: 1094 LDECAFPGVC----PSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQ------ 1143
Query: 468 SPGVGGAGVGAGGQGPIIT--GLTILNQTI----DICKHHANLCLNGRCIPTVSSYRCEC 521
S +GG G + G + N T+ + C + +G C+ + S+ C C
Sbjct: 1144 SSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLC 1203
Query: 522 NMGYKQDANG-DCIDVDEC-TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDEC 579
G+ G C DVDEC T++PC G CVNT GS+ C C GFQ +P C+DIDEC
Sbjct: 1204 APGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDEC 1263
Query: 580 IQNG-VLCKNGRCVNTDGSFQCI--CNAGFELTTDGKNCVDHDECTTTNMC-LNGMCINE 635
G +C +C N+ GS++C+ C GF + +G +C+D DEC MC +G C N
Sbjct: 1264 EDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNT 1322
Query: 636 DGSFKCICKPGFVLAPNGRYCTDVDECQTP-GICMNGHCINSEGSFRCDCPPGLAV---- 690
DGSF+C+C GF ++P+G C DV+EC+ +C C N EGSF C C L
Sbjct: 1323 DGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQ 1382
Query: 691 -------GMDGRVCVDTHM--------RSTCYGGIK-KGVCVRPFPGAVTKSECCCANPD 734
G G+ + R CY G K C T++ECCC
Sbjct: 1383 EGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ-G 1441
Query: 735 YGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCN 794
+G+ C CP+++SAEF +C SG G I G + Y
Sbjct: 1442 ASWGDACDLCPSEDSAEFSEICPSGKGY---------------IPVEGAWTFGQTMYT-- 1484
Query: 795 CNSGYEPDASGRNCIDIDECLV-NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDI 853
D DEC++ LC NG C NT Y C C PG+ + + CED
Sbjct: 1485 ---------------DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDH 1529
Query: 854 NECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT------------CWLN 901
+EC+ C NG C N GSF+C CSP L + C++S T CW
Sbjct: 1530 DECQDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKK 1589
Query: 902 IQDSRCEVNING-ATLKSECCATLGAAWGSPCERC 935
+ + C + G T +ECC G AW C C
Sbjct: 1590 VTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALC 1624
Score = 316 bits (810), Expect = 2e-85
Identities = 237/766 (30%), Positives = 330/766 (43%), Gaps = 146/766 (19%)
Query: 2065 NICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA 2124
N+C G+C N P G++C+C PG+ L + C D + G+C N +
Sbjct: 854 NVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRC-----INRVGS 908
Query: 2125 KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTRE--DVNECLESPGIC 2182
C C G+ T+ + T+E D+NEC E PG+C
Sbjct: 909 YSC--------------------------FCYPGY-TLATSGATQECQDINEC-EQPGVC 940
Query: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFEC-NCNE 2241
S GQC NT+GS+ CEC GY + G C D +EC C +G C N GS+ C C E
Sbjct: 941 SGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPGTCPDGRCVNSPGSYTCLACEE 999
Query: 2242 GFEPGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAE 2300
G+ G +C D+NEC P +CA +C N GS+ C+C GY + D+K C+D+DECA
Sbjct: 1000 GYR-GQSGSCVDVNECL-TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS 1057
Query: 2301 GLHDCESRGMMCKNLIGTFMC-ICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIG 2359
C + +C N G+F C C G DG C D +EC PG+C +G C N G
Sbjct: 1058 RA-SCPTG--LCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAG 1113
Query: 2360 SYRC-ECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGW 2418
S+ C +C+ G++ S G C D + E Q+ C + +N V +C C G
Sbjct: 1114 SFSCKDCDGGYRPSPLGDSCEDVDE----CEDPQSSC-LGGECKNTVGSYQCLCPQGFQL 1168
Query: 2419 GHQCELCPLPGTAQYKKIC-PHG--------------PGYT-----TDGRDIDECKVMPN 2458
+ +C ++ C PHG PG+ T +D+DEC +
Sbjct: 1169 ANGT-VCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATT-D 1226
Query: 2459 LCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC- 2515
C G C+NT GSF C C+ G+ C+D+DEC P + C+N+ GSY+C
Sbjct: 1227 PCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCV 1286
Query: 2516 -SCPRGYVLQEDGKTCKDLDECQTKQH-NCQFLCVNTLGGFTCKCPPGFTQHHTA--CID 2571
C G+ + +G C D+DEC C NT G F C C GF + C+D
Sbjct: 1287 LGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1345
Query: 2572 NNECGSQPSLCGAKGICQNTPGSFSCECQRGFS-LDATGLNC-------EDVDECD-GNH 2622
NEC ++CGA +C+N GSF C C DA +C + + E G+H
Sbjct: 1346 VNECELMLAVCGA-ALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDH 1404
Query: 2623 R-------CQHG------CQNILG----------------GYRCG-------------CP 2640
C G C ++LG G C CP
Sbjct: 1405 APAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICP 1464
Query: 2641 --QGYIQ-----HYQWNQCVDENECS--NPNACGSASCYNTLGSYKCACPSGFSFDQFSS 2691
+GYI + D +EC P C + C NT+ Y C C GF +D
Sbjct: 1465 SGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK 1524
Query: 2692 ACHDVNECSSSKNPCNYG-CSNTEGGYLCGC-PPGYYRVGQGHCVS 2735
C D +EC C G C NTEG + C C PP + Q C++
Sbjct: 1525 KCEDHDECQDL--ACENGECVNTEGSFHCFCSPPLTLDLSQQRCMN 1568
Score = 219 bits (558), Expect = 3e-56
Identities = 222/827 (26%), Positives = 306/827 (37%), Gaps = 231/827 (27%)
Query: 80 QDVLRGPNVCGSRFHSYCC---PGWKTLPGGNQCIVPICRNSCGD-GFCSRPNMCTCSSG 135
+D +G C +R SY C PG+ G C D C +P +C S G
Sbjct: 893 RDPCKGKGRCINRVGSYSCFCYPGYTLATSG-------ATQECQDINECEQPGVC--SGG 943
Query: 136 QISSTCGS-------------KSIQQCSVRCMNGGTCADDHC----------QCQKGYIG 172
Q ++T GS K Q C + GTC D C C++GY G
Sbjct: 944 QCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRG 1003
Query: 173 TYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQ---L 229
G V N C G C +C + G CE+ Y + + CQ
Sbjct: 1004 Q-SGSCVDVNECLTPGVC-AHGKCTNLEGSFRCSCEQGYEVTS-----DEKGCQDVDECA 1056
Query: 230 TGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQG 289
+ C LC T G C A C G+ N AC+D+DEC A PG+C
Sbjct: 1057 SRASCPTGLCLNTEGSF------ACSA----CENGYWVNEDGTACEDLDEC-AFPGVCPS 1105
Query: 290 GNCINTVGSFECR-CPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRG 348
G C NT GSF C+ C G++ S CED+DEC C GEC NTVGSY C+CP+G
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQG 1165
Query: 349 YVTSTDGSRCIDQRTGMCFSGLV-NGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPV 407
+ + +G+ C D M +G C C C PG
Sbjct: 1166 FQLA-NGTVCEDVNECMGEEHCAPHGECLNS----HGSFFCLCAPGFV------------ 1208
Query: 408 RGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF 467
S E C D + A + P GG+ G+ N TGF P P
Sbjct: 1209 --SAEGGTSCQD------VDECATTDP-CVGGHCVNTEGSFNCLCE--TGFQPSP----- 1252
Query: 468 SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHAN-LCLNGRCIPTVSSYRC--ECNMG 524
G + ID C+ + + +C +C + SYRC C G
Sbjct: 1253 ------------ESGECV--------DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPG 1292
Query: 525 YKQDANGDCIDVDECTSNPC--TNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQN 582
+ NGDCID+DEC ++ ++G C NT GS+ C C GF+ +P+ C+D++EC
Sbjct: 1293 FHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELM 1352
Query: 583 GVLCKNGRCVNTDGSFQCICNAGF-ELTTDGKNC---------------VDHDECTTTNM 626
+C C N +GSF C+C + E +C DH T
Sbjct: 1353 LAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMD 1412
Query: 627 CLNG---------------------------------MCINEDGS-FKCICKPGFVLAP- 651
C +G +C +ED + F IC G P
Sbjct: 1413 CYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPV 1472
Query: 652 NGRYC------TDVDECQT--PGICMN--------------------------------- 670
G + TD DEC PG+C N
Sbjct: 1473 EGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC 1532
Query: 671 -------GHCINSEGSFRCDCPPGLAVGMDGRVCV------------DTHMRSTCYGGIK 711
G C+N+EGSF C C P L + + + C+ D HM C+ +
Sbjct: 1533 QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHM-DICWKKVT 1591
Query: 712 KGVCVRPFPG-AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCS 757
VC P G T +ECCC + + + + C CP ++S + LC+
Sbjct: 1592 NDVCSEPLRGHRTTYTECCCQDGE-AWSQQCALCPPRSSEVYAQLCN 1637
Score = 179 bits (453), Expect = 5e-44
Identities = 149/532 (28%), Positives = 203/532 (38%), Gaps = 76/532 (14%)
Query: 97 CCPGWKTLPGGNQCIVPICRNS--CGD-GFCSRPN---MCTCSSGQISSTCG--SKSIQQ 148
C PG+ P G+ + C N CG GFC + C C G S G + +
Sbjct: 1289 CQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNE 1348
Query: 149 CSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGG-RCIGPNRCACVYGFTGPQC 207
C + C C+ +G C + E Q G R G + TG
Sbjct: 1349 CELML---AVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHA 1405
Query: 208 ERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ-------P 260
R Q + C L G T+ CC T G +WG C++CP++ P
Sbjct: 1406 PAPTRMDCYSGQKGHAPCSSVL-GRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICP 1464
Query: 261 CRRGFIP-----NIRTGACQDVDECQAI-PGICQGGNCINTVGSFECRCPAGHKQSETTQ 314
+G+IP D DEC PG+C G C+NTV + C C G + +
Sbjct: 1465 SGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK 1524
Query: 315 KCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCI------------DQR 362
KCED DEC + CE GEC NT GS+ C C RC+ D
Sbjct: 1525 KCEDHDECQDL--ACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIH 1582
Query: 363 TGMCFSGLVNGRCAQELPG-RMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGL 421
+C+ + N C++ L G R T +CCC+ G W CP R SE Y +LC
Sbjct: 1583 MDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQC--ALCPPRSSEVYAQLCNVAR 1640
Query: 422 PMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF--SPGVGGAGVGAG 479
RPG G G + + YGP G F G P +
Sbjct: 1641 IEAEREAGVHFRPGYEYGPG-PDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSA 1699
Query: 480 GQGPIITGLTILNQTIDICKHHA---------------------NLCLNGRCIPTVSSYR 518
+ PI+ Q ++ H+ N C NGRC+ Y
Sbjct: 1700 DRTPILESPL---QPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYT 1756
Query: 519 CECNMGYKQD-ANGDCIDVDEC--TSNP---CTNGDCVNTPGSYYCKCHAGF 564
C+C G++ D A+ C+DV+EC + P C +G C NT GSY C C G+
Sbjct: 1757 CDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 108 bits (269), Expect = 1e-22
Identities = 72/230 (31%), Positives = 95/230 (41%), Gaps = 54/230 (23%)
Query: 1576 VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWG-NPCETCPPVNSTEYYTLCP 1634
+G CYL + C + ++ CC S+G WG C CPP
Sbjct: 551 LGRCYLN-----TVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPP----------- 594
Query: 1635 GGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDID 1694
P + ++E+ Q ECPQGY T C+DI+
Sbjct: 595 -------RPASPVIEN----------------------GQLECPQGYKRLNLTH-CQDIN 624
Query: 1695 ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD-----MRKSFCYRSYNGTTC 1749
EC G+C C NT G+Y C C P M C+ M + CYRS TC
Sbjct: 625 ECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC 683
Query: 1750 ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTF 1799
L +TK++CCC+ VGKAW CE CP PGT F+ IC G+T+
Sbjct: 684 TLPLAQRITKQICCCS-RVGKAWGSECEKCPLPGTEAFREICPAGHGYTY 732
Score = 90.1 bits (222), Expect = 3e-17
Identities = 47/130 (36%), Positives = 67/130 (51%), Gaps = 14/130 (10%)
Query: 1517 CDDGYE-LDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
C GY+ L+ T +C DI+EC C + CVNT G Y C C P L+P+ CV ++
Sbjct: 608 CPQGYKRLNLT--HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 1576 V-----GNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS-LGKAWGNPCETCPPVNSTEY 1629
G CY GP +C + +++ CCCS +GKAWG+ CE CP + +
Sbjct: 666 AISMLQGLCYRSLGPG-----TCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAF 720
Query: 1630 YTLCPGGEGF 1639
+CP G G+
Sbjct: 721 REICPAGHGY 730
Score = 69.3 bits (168), Expect = 5e-11
Identities = 35/84 (41%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 2657 ECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNP---CNYG-CSN 2712
EC N C + C Y C C GF D AC DVNEC P C +G C N
Sbjct: 1736 ECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCEN 1795
Query: 2713 TEGGYLCGCPPGYY-RVGQGHCVS 2735
TEG Y C C PGY G HC +
Sbjct: 1796 TEGSYRCHCSPGYVAEAGPPHCTA 1819
Score = 66.2 bits (160), Expect = 4e-10
Identities = 44/116 (37%), Positives = 51/116 (43%), Gaps = 24/116 (20%)
Query: 39 RPQPPPQQVRSATAGSEGGFLAPEYR------------EEGAAVASRVRRRGQQDVLRGP 86
R QPP Q RS G + AP R GAA + R R L G
Sbjct: 114 RVQPPAQTRRSTPLGQQQP--APRTRAAPALPRLGTPQRSGAAPPTPPRGR-----LTGR 166
Query: 87 NVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGD-GFCSRPNMCTCSSGQISSTC 141
NVCG + CCPGW T N CI P+C C + G CSRP +C C SG + C
Sbjct: 167 NVCGGQ----CCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARC 218
Score = 62.0 bits (149), Expect = 8e-09
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 1493 DECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD----PINCVNGLCV 1548
+EC N C G C + + C C +G++LD C D++EC D + CV+G C
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 1549 NTPGRYECNCPPDF 1562
NT G Y C+C P +
Sbjct: 1795 NTEGSYRCHCSPGY 1808
Score = 59.7 bits (143), Expect = 4e-08
Identities = 31/79 (39%), Positives = 40/79 (50%), Gaps = 10/79 (12%)
Query: 2576 GSQPSLCGAKGICQN-----TPGSFSCECQRGFSLDATGLNCEDVDECDGNH----RCQH 2626
G Q CG C+N ++C+C GF LDA + C DV+ECD + C H
Sbjct: 1731 GLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 2627 G-CQNILGGYRCGCPQGYI 2644
G C+N G YRC C GY+
Sbjct: 1791 GYCENTEGSYRCHCSPGYV 1809
Score = 53.5 bits (127), Expect = 3e-06
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 2616 DECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSASCY 2670
+EC + C++G C + GY C C +G+ CVD NEC + N C C
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 2671 NTLGSYKCACPSGF 2684
NT GSY+C C G+
Sbjct: 1795 NTEGSYRCHCSPGY 1808
Score = 50.4 bits (119), Expect = 2e-05
Identities = 53/210 (25%), Positives = 76/210 (36%), Gaps = 57/210 (27%)
Query: 1740 CYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKP-CEPCPTPGTADFKTICGNIPGFT 1798
CY + C N L T+ CC + VG W C PCP
Sbjct: 554 CYLNTVNGQCANPLLELTTQEDCCGS--VGAFWGVTLCAPCPP----------------- 594
Query: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGD 1858
+ + NG + ECP G+ +L C+DI+EC
Sbjct: 595 --------------RPASPVIENG---------QLECPQGYKRLNLTH-CQDINECLTL- 629
Query: 1859 NLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCS-HGLCVDLQGSYQC 1917
LC ++A+C+N+ GSY C C G L P+ R+ C+ + GLC G C
Sbjct: 630 GLC-KDAECVNTRGSYLCTCRPGLMLDPS-----RSRCVSDKAISMLQGLCYRSLGPGTC 683
Query: 1918 ICHNGFKASQDQTMCMDV-----DECERHP 1942
+ ++ C V ECE+ P
Sbjct: 684 TLPLAQRITKQICCCSRVGKAWGSECEKCP 713
Score = 47.0 bits (110), Expect = 3e-04
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 9/60 (15%)
Query: 149 CSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCE 208
C +C G T A+ C K PVCE CQN G C P C C GF G +CE
Sbjct: 169 CGGQCCPGWTTANSTNHCIK---------PVCEPPCQNRGSCSRPQLCVCRSGFRGARCE 219
Score = 42.4 bits (98), Expect = 0.007
Identities = 29/113 (25%), Positives = 42/113 (37%), Gaps = 12/113 (10%)
Query: 1265 ECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
+ C +GY + + C DI+EC +C +C N G Y C C G M C+
Sbjct: 605 QLECPQGYKRL-NLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCV 662
Query: 1325 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDV-----DECE 1372
+ + G C + G C L + K C+ V ECE
Sbjct: 663 SDKAISM-----LQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECE 710
Score = 37.0 bits (84), Expect = 0.29
Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 1534 DECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP 1585
+EC C NG CV Y C+C FQL+ + CVD V C GP
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD--VNECDDLNGP 1784
Score = 35.0 bits (79), Expect = 1.1
Identities = 25/97 (25%), Positives = 33/97 (34%), Gaps = 2/97 (2%)
Query: 651 PNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGI 710
P G +EC C NG C+ + CDC G + CVD + G
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNG-- 1783
Query: 711 KKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAK 747
+CV + S C +P Y C AK
Sbjct: 1784 PAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAK 1820
Score = 33.5 bits (75), Expect = 3.2
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
C GY + T C D++EC + C A C+N GS+ C+CR G
Sbjct: 608 CPQGYK-RLNLTHCQDINEC-LTLGLCK-DAECVNTRGSYLCTCRPG 651
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 489 bits (1259), Expect = e-137
Identities = 429/1425 (30%), Positives = 603/1425 (42%), Gaps = 264/1425 (18%)
Query: 1370 ECEIGAHNCDMHASCLNIP-GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNT 1428
+C G C C+ G+ C C EG++G C D C ++C CV
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE--YCQHRDPCEK--NRCQNGGTCVAQ 82
Query: 1429 P--GSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVP-GAYRCECEMGFTPASD 1485
G C C+ GFTG+ S C + G C + Y C C++GFT
Sbjct: 83 AMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT---- 138
Query: 1486 SRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVN 1544
+ CQ D C TC + F C C G+ TG C TD++EC P +C +
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH 194
Query: 1545 G-LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR 1603
G C+N PG Y+C CP F TG C + Y+ P
Sbjct: 195 GGTCLNLPGSYQCQCPQGF----TGQYC-----DSLYVPCAP------------------ 227
Query: 1604 SSCCCSLGKAWGNPCETCPPVNSTEYYTLC-PGGEGFRPNPITIILEDIDECQELPGLCQ 1662
S C + G TC + C PG EG + +ID+C CQ
Sbjct: 228 -SPCVNGG--------TCRQTGDFTFECNCLPGFEG------STCERNIDDCPN--HRCQ 270
Query: 1663 -GGNCINTFGSFQCECPQGYYLSEDTRIC-EDIDECFAHPGVC-GPGTCYNTLGNYTCIC 1719
GG C++ ++ C CP + + C ED+DEC P C GTC N G Y C+C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Query: 1720 PPEYMQVNG--GHNCMDMRKSFCYRSYN-GTTCENELPFNVTKRMCCCTYNVGKAW---- 1772
VNG G +C + + S G+TC + V C C GKA
Sbjct: 327 ------VNGWSGDDCSENIDDCAFASCTPGSTCIDR----VASFSCMCPE--GKAGLLCH 374
Query: 1773 -NKPC--EPCPTPGTADFKTICGNIPGFTFDIHTGK--AVDIDECKEI-PGICAN-GVCI 1825
+ C PC D + G + G D+DEC C + G C+
Sbjct: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
Query: 1826 NQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL 1884
N G+F CEC G++ CE DI+EC + CQ +A C++ G + C C GFK
Sbjct: 435 NTDGAFHCECLKGYAGPR----CEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK- 487
Query: 1885 SPNGAC-VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPC 1943
C ++ NEC P V ++G CVD +QC+C GF Q +D+D+C PC
Sbjct: 488 --GVHCELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPC 541
Query: 1944 GNGT-CKNTVGSYNCLCYPGFE--LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
NG C + Y C C GF L N ID C C +G+C + I S+ C+
Sbjct: 542 LNGAKCIDHPNGYECQCATGFTGVLCEEN----IDNCDP---DPCHHGQCQDGIDSYTCI 594
Query: 2001 CNEGYELTPDGKNCIDT-NECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC-IDIN 2058
CN GY G C D +EC + P + G C +L ++C C PG NC I+ +
Sbjct: 595 CNPGYM----GAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG--TSGVNCEINFD 647
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2118
+C +P C+ G C + + C+C PGF G+RC N + +C+
Sbjct: 648 DCASNP--CIHGICMDGINRYSCVCSPGFT----GQRC----------NIDIDECASNPC 691
Query: 2119 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2178
K C + + G F+ +CP G P VNECL +
Sbjct: 692 ---RKGATCINGVNG-----------------FRCICPEG----PHHPSCYSQVNECLSN 727
Query: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFE 2236
P C +G C ++C C G+ G+ C VD +EC + NPC NG TC N++ +
Sbjct: 728 P--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC-LSNPCQNGGTCDNLVNGYR 780
Query: 2237 CNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDL 2295
C C +GF+ NC+ +I+ECA NP L C + Y C C + Y + Q + L
Sbjct: 781 CTCKKGFKG---YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTV---L 834
Query: 2296 DECAEGLHDCESRGMMCKNL--IGTFMCICPPGMARRPDGEGC-VDENECRTKPGICEN- 2351
C+ + CE+ + CK ++ C+C PG G+ C +D +EC +KP C N
Sbjct: 835 APCSP--NPCENAAV-CKESPNFESYTCLCAPGW----QGQRCTIDIDECISKP--CMNH 885
Query: 2352 GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECC 2411
G C N GSY CEC GF SG +C ++ + L CQ S + V C
Sbjct: 886 GLCHNTQGSYMCECPPGF----SGMDCEED-----IDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 2412 CDGGRGWGHQC---------ELCPLPGTAQ-----YKKICPHGPGYTTDGRDIDECKVMP 2457
C G G +C E C GT Y C G +I+EC
Sbjct: 937 CLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECT--E 993
Query: 2458 NLCTNG-QCINTMGSFRCFCKVGYTTDISGTSCI-DLDECSQSPKPCNYICKNTEGSYQC 2515
+ C NG C++ + SF C C VG+T G+ C+ +++ECS P C + G+Y+C
Sbjct: 994 SSCFNGGTCVDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTYRC 1049
Query: 2516 SCPRGYVLQEDGKTCKDL-DECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNE 2574
SCP GY GK C+ L + C + CV C CP G+ + + N
Sbjct: 1050 SCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD-VPNVS 1104
Query: 2575 CGSQPS--------LCGAKGICQNTPGSFSCECQRGFSLDATGLNCED-VDECDGNHRCQ 2625
C S LC G+C N + C+C G+ TG CE+ +DEC N CQ
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECASNP-CQ 1159
Query: 2626 HG--CQNILGGYRCGCPQGYIQHYQWNQCVDE-NECSNPNACGSASCYNTLGSYKCACPS 2682
HG C + +GGYRC C GY Q C E +EC N +C + + +KC+CP
Sbjct: 1160 HGATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPP 1215
Query: 2683 GFSFDQFSSACHD-VNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
G C + +++C+ + N G C + GGY C C PG+
Sbjct: 1216 GTR----GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256
Score = 468 bits (1203), Expect = e-131
Identities = 439/1521 (28%), Positives = 628/1521 (41%), Gaps = 329/1521 (21%)
Query: 153 CMNGGTCADDH-----CQCQKGYIGTYCGQ--PVCENGCQNGGRCI-----GPNRCACVY 200
C+N G C H C+C +G++G YC P +N CQNGG C+ G C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 201 GFTGPQCERDYRTG-PCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ 259
GFTG C+ Y T PCF V+ G ++ T C
Sbjct: 95 GFTGEDCQ--YSTSHPCF--VSRPCLNGGTCHMLSRDTYECT------------------ 132
Query: 260 PCRRGFIPNIRTGA-CQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE- 317
C+ GF TG CQ D C + P G C F C+C G T QKCE
Sbjct: 133 -CQVGF-----TGKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTGF----TGQKCET 181
Query: 318 DIDECSIIPGICETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCA 376
D++EC I PG C+ G C N GSY C CP+G+ S + C +G G C
Sbjct: 182 DVNECDI-PGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNG---GTCR 237
Query: 377 QELPGRMTKMQCCCEPG----------------RCW-------GIGTIPEACPVRGSEEY 413
Q G T +C C PG RC G+ T CP + + ++
Sbjct: 238 QT--GDFT-FECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQF 294
Query: 414 RRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGG 473
C + + + +A + GGT N GG G + + G +G
Sbjct: 295 ---CTEDVDECLLQPNA-CQNGGTCANR-----------NGGYGCVCVNGWSGDD----- 334
Query: 474 AGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDC 533
++ ID C A+ CI V+S+ C C G A C
Sbjct: 335 -----------------CSENIDDCAF-ASCTPGSTCIDRVASFSCMCPEG---KAGLLC 373
Query: 534 IDVDECTSNPCTNGDCVNTP---GSYYCKCHAGFQRTPTKQACIDIDEC-IQNGVLCKN- 588
D C SNPC G +T G Y C C G++ + D+DEC + N C++
Sbjct: 374 HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE---DVDECAMANSNPCEHA 430
Query: 589 GRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPGF 647
G+CVNTDG+F C C G+ G C +D +EC + + C+++ G F C+C PGF
Sbjct: 431 GKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
Query: 648 VLAPNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVC---VDTHMR 703
G +C +++ECQ+ NG C++ F+C CPPG G VC +D
Sbjct: 487 ----KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSS 538
Query: 704 STCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT 763
+ C G K C +P+ G CQ C++G
Sbjct: 539 TPCLNGAK-----------------CIDHPN---GYECQ-------------CATGFTGV 565
Query: 764 VDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCID-IDECLVNRLLCD 822
+ +I+ C DPD C +G C++ SY C CN GY G C D IDEC + L D
Sbjct: 566 LCEENIDNC--DPDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDECYSSPCLND 619
Query: 823 NGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPCVNGACRNNLGSFNCECSPGS 881
G C + Y C C PG T CE + ++C SNPC++G C + + ++C CSPG
Sbjct: 620 -GRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG- 673
Query: 882 KLSSTGLIC---IDSL------KG-TCWLNIQDSRCEVNINGATLKSECCATLGAAWGSP 931
TG C ID KG TC + RC + G S C + + +P
Sbjct: 674 ---FTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPS-CYSQVNECLSNP 728
Query: 932 CERCELDTACPRGLARIK--------GVTCE-DVNECEVFPGVCPN-GRCVNSKGSFHCE 981
C + C GL+ K G+ CE D NEC P C N G C N + C
Sbjct: 729 C----IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNGYRCT 782
Query: 982 CPEGLTLDGTGRVCLDIRMEQCY-------------LKWDEDECIHPVPGKFRMDACCCA 1028
C +G G C + +++C + C+ P GK C
Sbjct: 783 CKKGF----KGYNC-QVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGK----NCQTV 833
Query: 1029 VGAAWGTECEEC----PKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMC 1084
+ CE P + Y LC G G+ DI+EC + P M
Sbjct: 834 LAPCSPNPCENAAVCKESPNFESYTCLCAPG---------WQGQRCTIDIDECISKPCM- 883
Query: 1085 TYGKCRNTIGSFKCRCNSGFA-LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECF 1143
+G C NT GS+ C C GF+ +D EE DID+C +P G G C++ +F C C
Sbjct: 884 NHGLCHNTQGSYMCECPPGFSGMDCEE----DIDDCLANPCQNG-GSCMDGVNTFSCLCL 938
Query: 1144 EGYESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDIN 1202
G+ K D++EC P C+ GGTC + S+ C C G + +IN
Sbjct: 939 PGFTGD----KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCEN---NIN 989
Query: 1203 ECSLSDNLCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCT-DIDECMIMNGGCDTQCTNS 1260
EC +++ C N G CV+ I ++ C C G+ + C +I+EC + C +
Sbjct: 990 EC--TESSCFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCLNEGTCVDG 1043
Query: 1261 EGSYECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 1319
G+Y CSC GY G++C ++ C +P + G C E +CLC G+ +
Sbjct: 1044 LGTYRCSCPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQKKAESQCLCPSGWAGAY- 1097
Query: 1320 MKTCIDVN-ECD--------LNSNICMF-GECENTKGSFICHCQLGYSVKKGTTGCTDVD 1369
C N CD L ++C G C N + C C LGY+ G+ +D
Sbjct: 1098 ---CDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT---GSYCEEQLD 1151
Query: 1370 ECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNT 1428
EC ++ C A+C + G ++C C G+ G+ C ++DEC N C C++
Sbjct: 1152 EC--ASNPCQHGATCSDFIGGYRCECVPGY--QGVNCEYEVDECQN--QPCQNGGTCIDL 1205
Query: 1429 PGSYRCACSEGFTGDGFTCSD-VDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSR 1487
++C+C G G C + +D+CA + GQC++ G Y C C GF + R
Sbjct: 1206 VNHFKCSCPPGTR--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF---AGER 1260
Query: 1488 SCQDIDECSFQNICVFGT--CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNG 1545
DI+EC G+ C L + C+C + TG +C + + C+NG
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNG 1316
Query: 1546 ----LCVNTPGRYECNCPPDF 1562
+ N P + C CPP F
Sbjct: 1317 GTCAVASNMPDGFICRCPPGF 1337
Score = 456 bits (1172), Expect = e-127
Identities = 455/1639 (27%), Positives = 662/1639 (40%), Gaps = 339/1639 (20%)
Query: 586 CKN-GRCVNT-DGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG-MCINED--GSFK 640
C N G CV +G+ C C GF G+ C D C N C NG C+ + G
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFL----GEYCQHRDPCEK-NRCQNGGTCVAQAMLGKAT 89
Query: 641 CICKPGFVLAPNGRYCTDVDECQTPGICMNGHCIN--SEGSFRCDCPPGLAVGMDGRVC- 697
C C GF + +Y T C C+NG + S ++ C C VG G+ C
Sbjct: 90 CRCASGFT-GEDCQYSTS-HPCFVSRPCLNGGTCHMLSRDTYECTCQ----VGFTGKECQ 143
Query: 698 -VDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF-GEPCQPCPAKNSAEFHGL 755
D + C G F C C GF G+ C+
Sbjct: 144 WTDACLSHPCANGSTCTTVANQF-------SCKCLT---GFTGQKCET------------ 181
Query: 756 CSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL 815
D+NEC + G C NL GSY+C C G+ +G+ C +
Sbjct: 182 ------------DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPC 225
Query: 816 VNRLLCDNGLCRNTPG-SYSCTCPPGYVFRTETETCE-DINECESNPCVN-GACRNNLGS 872
+ G CR T ++ C C PG+ E TCE +I++C ++ C N G C + + +
Sbjct: 226 APSPCVNGGTCRQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNT 281
Query: 873 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC 932
+NC C P TG C + + C L Q + C+ NG T CA +G C
Sbjct: 282 YNCRCPP----QWTGQFCTEDV-DECLL--QPNACQ---NGGT-----CANRNGGYGCVC 326
Query: 933 ERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 992
C E++++C F P C++ SF C CPEG G
Sbjct: 327 VNGWSGDDC-----------SENIDDC-AFASCTPGSTCIDRVASFSCMCPEG----KAG 370
Query: 993 RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLC 1052
+C +D C + G C+ P G +Y C
Sbjct: 371 LLC-------------------------HLDDACISNPCHKGALCDTNPLNG--QYICTC 403
Query: 1053 PRGAGFANRGDVLTGRPFYKDINEC-KAFPGMCTY-GKCRNTIGSFKCRCNSGFALDMEE 1110
P+G G +D++EC A C + GKC NT G+F C C G+A
Sbjct: 404 PQG---------YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA---GP 451
Query: 1111 RNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLC 1169
R DI+EC P C++ G F C C G++ +C ++I+EC+ NP +
Sbjct: 452 RCEMDINECHSDP-CQNDATCLDKIGGFTCLCMPGFKG-----VHCELEINECQSNPCV- 504
Query: 1170 RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQCSCN 1228
G CV+ FQC CP G + +DI++CS + C NG KC++ Y+C C
Sbjct: 505 NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTP--CLNGAKCIDHPNGYECQCA 559
Query: 1229 PGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD-IDEC 1287
G+ + + D +G QC + SY C C+ GY G C+D IDEC
Sbjct: 560 TGFTGVLCEENIDNCDPDPCHHG----QCQDGIDSYTCICNPGYM----GAICSDQIDEC 611
Query: 1288 ENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGS 1347
++P + D G+C ++ Y+C C G ++N D SN C+ G C +
Sbjct: 612 YSSPCLND-GRCIDLVNGYQCNCQPGTSG-----VNCEINFDDCASNPCIHGICMDGINR 665
Query: 1348 FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCRE---------- 1397
+ C C G++ G D+DEC ++ C A+C+N F+C C E
Sbjct: 666 YSCVCSPGFT---GQRCNIDIDEC--ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 1398 ---------------------------GWIGNGIKC-IDLDECSNGTHQCSINAQCVNTP 1429
GW+ GI C +D +EC ++ C C N
Sbjct: 721 VNECLSNPCIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECL--SNPCQNGGTCDNLV 776
Query: 1430 GSYRCACSEGFTGDGFTCS-DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRS 1488
YRC C +GF G+ C ++DECA N L G C + Y C C + +T ++
Sbjct: 777 NGYRCTCKKGF--KGYNCQVNIDECASNPCL-NQGTCFDDISGYTCHCVLPYT----GKN 829
Query: 1489 CQDIDECSFQNICV-FGTCNNLPGM--FHCICDDGYELDRTGGNCT-DIDECADPINCVN 1544
CQ + N C C P + C+C G++ G CT DIDEC +
Sbjct: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCMNH 885
Query: 1545 GLCVNTPGRYECNCPPDFQLNPTGVGC---VDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1601
GLC NT G Y C CPP F +G+ C +D+ + N G DG + + G
Sbjct: 886 GLCHNTQGSYMCECPPGF----SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF 941
Query: 1602 SRSSCCCSLGKAWGNPCE---TCPP-VNSTEYYTLCPGG-EGFRPNPITIILEDIDECQE 1656
+ C + + PC+ TC VNS Y C G +G +I+EC E
Sbjct: 942 TGDKCQTDMNECLSEPCKNGGTCSDYVNS--YTCKCQAGFDGVHCE------NNINECTE 993
Query: 1657 LPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYT 1716
GG C++ SF C CP G+ + +I+EC +HP GTC + LG Y
Sbjct: 994 -SSCFNGGTCVDGINSFSCLCPVGF---TGSFCLHEINECSSHP-CLNEGTCVDGLGTYR 1048
Query: 1717 CICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPC 1776
C CP Y G NC + + C RS C+N K C V K C
Sbjct: 1049 CSCPLGYT----GKNCQTL-VNLCSRS----PCKN-------KGTC-----VQKKAESQC 1087
Query: 1777 EPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDE--CKEIPGICANGVCINQIGSFRCE 1834
CP+ + C ++P + DI + + E C+ +GVCIN + C+
Sbjct: 1088 -LCPSGWAGAY---C-DVPNVSCDIAASRRGVLVEHLCQH------SGVCINAGNTHYCQ 1136
Query: 1835 CPTGFSYNDLLLVCED-IDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDR 1893
CP G++ + CE+ +DEC++ N CQ A C + G YRCEC G++ VD
Sbjct: 1137 CPLGYTGS----YCEEQLDECAS--NPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVD- 1189
Query: 1894 NECLEIPNVCSH-GLCVDLQGSYQCICHNGFKASQDQTMCMD-VDECERHP-CGN-GTCK 1949
EC P C + G C+DL ++C C G + +C + +D+C R P C N G C
Sbjct: 1190 -ECQNQP--CQNGGTCIDLVNHFKCSCPPGTRG----LLCEENIDDCARGPHCLNGGQCM 1242
Query: 1950 NTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP 2009
+ +G Y+C C PGF DI+EC S + C + C+C +
Sbjct: 1243 DRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---- 1296
Query: 2010 DGKNC-IDTNECVALPGSCSPGTC---QNLEGSFRCICPPGYE-VKSENCIDINECDEDP 2064
G++C + C +P + GTC N+ F C CPPG+ + ++ +C +
Sbjct: 1297 TGRHCETFVDVCPQMP-CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGE 1355
Query: 2065 NICLFGSCTNTPGGFQCLCP------PGFVLS--DNGRRCFDTRQ-----SFCFTNFENG 2111
C +T G +C CP G S +G C RQ C F
Sbjct: 1356 ------QCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGS 1409
Query: 2112 KCSVPKAFNTTKAKCCCSK 2130
+C + A +T C S+
Sbjct: 1410 RCELYTAPPSTPPATCLSQ 1428
Score = 455 bits (1170), Expect = e-127
Identities = 426/1471 (28%), Positives = 622/1471 (42%), Gaps = 303/1471 (20%)
Query: 790 SYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETET 849
++ C GYEP C++ C+ G+ C CP G++ E
Sbjct: 23 AHALQCRDGYEP------CVNEGMCVTYH-----------NGTGYCKCPEGFL----GEY 61
Query: 850 CEDINECESNPCVNGA---CRNNLGSFNCECSPGSKLS----STGLICIDSLK----GTC 898
C+ + CE N C NG + LG C C+ G ST C S GTC
Sbjct: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
Query: 899 WLNIQDS---RCEVNINGATLK-SECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE 954
+ +D+ C+V G + ++ C + A GS C +C + L G CE
Sbjct: 122 HMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC-KCLTGFTGQKCE 180
Query: 955 -DVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
DVNEC++ PG C +G C+N GS+ C+CP+G TG+ C + Y+ C
Sbjct: 181 TDVNECDI-PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-----DSLYVPCAPSPC 230
Query: 1013 IH----PVPGKFRMDACCCAVGAAWGTECE----ECPK----------PGTKEYETLCPR 1054
++ G F + C C G G+ CE +CP G Y CP
Sbjct: 231 VNGGTCRQTGDFTFE-CNCLPGFE-GSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCP- 287
Query: 1055 GAGFANRGDVLTGRPFYKDINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNC 1113
TG+ +D++EC P C G C N G + C C +G++ D +C
Sbjct: 288 --------PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD----DC 335
Query: 1114 TD-IDECRISPDLCGSGICVNTPGSFECECFEGYESGFM-------MMKNCMDIDECERN 1165
++ ID+C + GS C++ SF C C EG ++G + + C C+ N
Sbjct: 336 SENIDDCAFASCTPGS-TCIDRVASFSCMCPEG-KAGLLCHLDDACISNPCHKGALCDTN 393
Query: 1166 PL----LC---------------------------RGGTCVNTEGSFQCDCPLGHELSPS 1194
PL +C G CVNT+G+F C+C G+ P
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY-AGPR 452
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD 1254
E +DINEC SD + C++ IG + C C PG++ +I+EC +
Sbjct: 453 CE--MDINECH-SDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVNN 506
Query: 1255 TQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDG 1313
QC + ++C C G+ G C DID+C + P + +G +C + P Y C C G
Sbjct: 507 GQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCL-NGAKCIDHPNGYECQCATG 561
Query: 1314 FMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 1373
F + + +++ CD + C G+C++ S+ C C GY G +DEC
Sbjct: 562 FTGVLCEE---NIDNCD--PDPCHHGQCQDGIDSYTCICNPGY---MGAICSDQIDECY- 612
Query: 1374 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSY 1432
+ C C+++ ++C+C+ G +G+ C I+ D+C++ I+ C++ Y
Sbjct: 613 -SSPCLNDGRCIDLVNGYQCNCQPG--TSGVNCEINFDDCASNP---CIHGICMDGINRY 666
Query: 1433 RCACSEGFTGDGFTCS-DVDECAENINLCENG-QCLNVPGAYRCECEMGFTPASDSRSC- 1489
C CS GFTG C+ D+DECA N C G C+N +RC C G SC
Sbjct: 667 SCVCSPGFTGQ--RCNIDIDECAS--NPCRKGATCINGVNGFRCICPEG----PHHPSCY 718
Query: 1490 QDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGLCV 1548
++EC N C+ G C + C+CD G+ G NC D +EC G C
Sbjct: 719 SQVNEC-LSNPCIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSNPCQNGGTCD 773
Query: 1549 NTPGRYECNCPPDFQLNPTGVGC---VDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 1605
N Y C C F+ G C +D N L G D + + +
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN 829
Query: 1606 CCCSLGKAWGNPCE---TCPPVNSTEYYT-LC-PGGEGFRPNPITIILEDIDECQELPGL 1660
C L NPCE C + E YT LC PG +G R TI DIDEC P +
Sbjct: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR---CTI---DIDECISKPCM 883
Query: 1661 CQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICP 1720
G C NT GS+ CECP G+ EDID+C A+P G G+C + + ++C+C
Sbjct: 884 -NHGLCHNTQGSYMCECPPGF---SGMDCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCL 938
Query: 1721 PEYMQVNGGHNCM-DMRKSFCYRSYNGTTCENELPFNVTKRMC-----CCTYNVGKAWNK 1774
P + G C DM + NG TC + + K C N+ +
Sbjct: 939 PGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES 994
Query: 1775 PCEPCPT--PGTADFKTICGNIPGFT--FDIHTGKAVDIDECKEIPGICAN-GVCINQIG 1829
C T G F +C GFT F +H +I+EC P C N G C++ +G
Sbjct: 995 SCFNGGTCVDGINSFSCLCP--VGFTGSFCLH-----EINECSSHP--CLNEGTCVDGLG 1045
Query: 1830 SFRCECPTGF----------------------------------------SYNDLLLVCE 1849
++RC CP G+ +Y D+ V
Sbjct: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC 1105
Query: 1850 DIDECSNG---DNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDR-NECLEIPNVCSH 1905
DI G ++LCQ + CIN+ ++ C+C G+ C ++ +EC N C H
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY---TGSYCEEQLDECAS--NPCQH 1160
Query: 1906 G-LCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGN-GTCKNTVGSYNCLCYPGF 1963
G C D G Y+C C G++ + +VDEC+ PC N GTC + V + C C PG
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCE---YEVDECQNQPCQNGGTCIDLVNHFKCSCPPG- 1216
Query: 1964 ELTHNNDCLD-IDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTPDGKNCI-DTNEC 2020
T C + ID+C+ G C N G+C + IG + C C G+ G+ C D NEC
Sbjct: 1217 --TRGLLCEENIDDCAR--GPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINEC 1268
Query: 2021 VALPGSCSPGT--CQNLEGSFRCICPPGYEVK-SENCIDINECDEDPNICLFGS----CT 2073
++ P S S G+ C L + C+C + + E +D+ C + P CL G +
Sbjct: 1269 LSNPCS-SEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDV--CPQMP--CLNGGTCAVAS 1323
Query: 2074 NTPGGFQCLCPPGFVLSDNGRRCFDTRQSFC 2104
N P GF C CPPGF +G RC QS C
Sbjct: 1324 NMPDGFICRCPPGF----SGARC----QSSC 1346
Score = 446 bits (1148), Expect = e-124
Identities = 448/1595 (28%), Positives = 633/1595 (39%), Gaps = 342/1595 (21%)
Query: 1095 SFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMK 1154
+++C C GF + C D C P GS C F C+C +GF K
Sbjct: 128 TYECTCQVGFT----GKECQWTDACLSHPCANGS-TCTTVANQFSCKCL----TGFTGQK 178
Query: 1155 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE--------LSPSREDCVDINEC-- 1204
D++EC+ GGTC+N GS+QC CP G + + CV+ C
Sbjct: 179 CETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQ 238
Query: 1205 ------------------------SLSDNLCRN-GKCVNMIGTYQCSCNPGYQATPDRQG 1239
++ C+N G CV+ + TY C C P + Q
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTG----QF 294
Query: 1240 CT-DIDECMIMNGGCDT--QCTNSEGSYECSCSEGYA----------------------- 1273
CT D+DEC++ C C N G Y C C G++
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354
Query: 1274 --------LMPDGRS---CADIDECENNPDICDGGQCTNIP--GEYRCLCYDGFMASMDM 1320
+ P+G++ C D C +NP G C P G+Y C C G+ +
Sbjct: 355 DRVASFSCMCPEGKAGLLCHLDDACISNP-CHKGALCDTNPLNGQYICTCPQGYKGA--- 410
Query: 1321 KTCIDVNECDL-NSNICMF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
DV+EC + NSN C G+C NT G+F C C GY+ G D++EC + C
Sbjct: 411 DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA---GPRCEMDINECH--SDPC 465
Query: 1379 DMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACS 1437
A+CL+ G F C C G+ G+ C ++++EC ++ C N QCV+ ++C C
Sbjct: 466 QNDATCLDKIGGFTCLCMPGF--KGVHCELEINECQ--SNPCVNNGQCVDKVNRFQCLCP 521
Query: 1438 EGFTGDGFTCS-DVDECAENINLCENG-QCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
GFTG C D+D+C+ C NG +C++ P Y C+C GFT ++ID C
Sbjct: 522 PGFTGP--VCQIDIDDCSS--TPCLNGAKCIDHPNGYECQCATGFTGVLCE---ENIDNC 574
Query: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD-IDECADPINCVNGLCVNTPGRY 1554
+ C G C + + CIC+ GY G C+D IDEC +G C++ Y
Sbjct: 575 D-PDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDECYSSPCLNDGRCIDLVNGY 629
Query: 1555 ECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV-GVSRSSCCCSLG-- 1611
+CNC P +GV C N +C S C I + G++R SC CS G
Sbjct: 630 QCNCQP----GTSGVNCEIN-FDDC---------ASNPCIHGICMDGINRYSCVCSPGFT 675
Query: 1612 ---------KAWGNPCE---TCPPVNSTE-YYTLCPGGEGFRPNPITIILEDIDECQELP 1658
+ NPC TC +N + +CP G P+ ++EC P
Sbjct: 676 GQRCNIDIDECASNPCRKGATC--INGVNGFRCICPEGP-HHPS----CYSQVNECLSNP 728
Query: 1659 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTCYNTLGNYTC 1717
C GNC ++C C G+ CE D +EC ++P G GTC N + Y C
Sbjct: 729 --CIHGNCTGGLSGYKCLCDAGWVGIN----CEVDKNECLSNPCQNG-GTCDNLVNGYRC 781
Query: 1718 ICPPEYMQVNGGHNCM----------DMRKSFCYRSYNGTTCENELPF---NVTKRMCCC 1764
C + G+NC + + C+ +G TC LP+ N + C
Sbjct: 782 TCKKGFK----GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPC 837
Query: 1765 TYNVGKAWNKPCEPC----PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 1820
+ N PCE +P + +C PG+ T +DIDEC P C
Sbjct: 838 SPN-------PCENAAVCKESPNFESYTCLCA--PGWQGQRCT---IDIDECISKP--CM 883
Query: 1821 N-GVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
N G+C N GS+ CECP GFS D EDID+C N CQ C++ ++ C C
Sbjct: 884 NHGLCHNTQGSYMCECPPGFSGMDCE---EDIDDCL--ANPCQNGGSCMDGVNTFSCLCL 938
Query: 1880 AGFKLSPNGACVDRNECLEIPNVCSH-GLCVDLQGSYQCICHNGFKASQDQTMC-MDVDE 1937
GF + + D NECL P C + G C D SY C C GF D C +++E
Sbjct: 939 PGF--TGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINE 990
Query: 1938 CERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCL-DIDECSSFFGQVCRN-GRCFNEI 1994
C C N GTC + + S++CLC GF + CL +I+ECSS C N G C + +
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFT---GSFCLHEINECSS---HPCLNEGTCVDGL 1044
Query: 1995 GSFKCLCNEGYELTPDGKNCID-TNECVALPGSCSPGTCQNLEGSFRCICPPGY-----E 2048
G+++C C GY GKNC N C P + GTC + +C+CP G+ +
Sbjct: 1045 GTYRCSCPLGY----TGKNCQTLVNLCSRSPCK-NKGTCVQKKAESQCLCPSGWAGAYCD 1099
Query: 2049 VKSENCIDINECDED---PNICLF-GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFC 2104
V + +C DI ++C G C N C CP G+ S+C
Sbjct: 1100 VPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT------------GSYC 1146
Query: 2105 FTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPS 2164
+ +C A N + CS G G CE P V C Y
Sbjct: 1147 EEQLD--EC----ASNPCQHGATCSDFIG---GYRCECVPGYQGVN----CEY------- 1186
Query: 2165 LHDTREDVNECLESPGICSN-GQCINTDGSFRCECPMGYNLDYTGVRCVDT-DECSIGNP 2222
+V+EC P C N G CI+ F+C CP G G+ C + D+C+ G
Sbjct: 1187 ------EVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPH 1234
Query: 2223 CGN-GTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLC--AFRCMNTFGSYECT 2278
C N G C + IG + C C GF CE DINEC NP + C+ Y C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAG---ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCV 1291
Query: 2279 CPIGYALREDQKMCKDLDECAEGLHDCESRG--MMCKNLIGTFMCICPPGMARRPDGEGC 2336
C + R + +D C + C + G + N+ F+C CPPG +
Sbjct: 1292 CRSAFTGRHCETF---VDVCPQ--MPCLNGGTCAVASNMPDGFICRCPPGFS-------- 1338
Query: 2337 VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQ 2396
RC + G +C E ++SG C C + + CQ
Sbjct: 1339 --------------GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQ 1384
Query: 2397 MASSSRNLVTKSECCCDGGRGW-GHQCELCPL-PGTAQYKKICPHGPGYTTDGRDIDECK 2454
S C + G +CEL P T + + DG + C
Sbjct: 1385 HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACN 1444
Query: 2455 VMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQ 2514
G C TM + C S C D C+ +C E +
Sbjct: 1445 SHACQWDGGDCSLTMENPWANCS-------SPLPCWDYIN-----NQCDELCNTVECLFD 1492
Query: 2515 CSCPRGYVLQEDGKTCKDLDEC--QTKQHNCQFLC 2547
+ Q + KTCK C K ++C C
Sbjct: 1493 -----NFECQGNSKTCKYDKYCADHFKDNHCDQGC 1522
Score = 443 bits (1139), Expect = e-123
Identities = 468/1651 (28%), Positives = 657/1651 (39%), Gaps = 424/1651 (25%)
Query: 543 PCTN-GDCVNTP-GSYYCKCHAGF------QRTP-TKQACIDIDECIQNGVL------CK 587
PC N G CV G+ YCKC GF R P K C + C+ +L C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
Query: 588 NG------------------RCVN-------TDGSFQCICNAGFELTTDGKNCVDHDECT 622
+G C+N + +++C C GF GK C D C
Sbjct: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF----TGKECQWTDAC- 148
Query: 623 TTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMN-GHCINSEGS 679
++ C NG C F C C GF G+ C TDV+EC PG C + G C+N GS
Sbjct: 149 LSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQHGGTCLNLPGS 204
Query: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF-G 738
++C CP G G+ C ++ + G C + G T EC C GF G
Sbjct: 205 YQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQ--TGDFT-FECNCLP---GFEG 254
Query: 739 EPCQ----PCPAKNSAEFHGLCSSGVGITVDGR------------DINECALDPDICAN- 781
C+ CP + + G+C GV T + R D++EC L P+ C N
Sbjct: 255 STCERNIDDCP-NHRCQNGGVCVDGVN-TYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
Query: 782 GICENLRGSYRCNCNSGYEPD--------------ASGRNCID----------------- 810
G C N G Y C C +G+ D G CID
Sbjct: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL 372
Query: 811 --IDECLVNRLLCDNGLCRNTP--GSYSCTCPPGYVFRTETETCEDINEC---ESNPCVN 863
+D+ ++ LC P G Y CTCP GY + ED++EC SNPC +
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY---KGADCTEDVDECAMANSNPCEH 429
Query: 864 -GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCA 922
G C N G+F+CEC LKG RCE++IN EC +
Sbjct: 430 AGKCVNTDGAFHCEC----------------LKG-----YAGPRCEMDIN------ECHS 462
Query: 923 TLGAAWGSPCERCELDTACPRGLA--------RIKGVTCE-DVNECEVFPGVCPNGRCVN 973
+ C+ D C + KGV CE ++NEC+ P V NG+CV+
Sbjct: 463 ----------DPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCV-NNGQCVD 511
Query: 974 SKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAW 1033
F C CP G TG VC I ++ C C++
Sbjct: 512 KVNRFQCLCPPGF----TGPVC-QIDIDDC----SSTPCLN------------------- 543
Query: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTI 1093
G +C + P YE C G TG ++I+ C P C +G+C++ I
Sbjct: 544 GAKCIDHP----NGYECQCATG---------FTGVLCEENIDNCD--PDPCHHGQCQDGI 588
Query: 1094 GSFKCRCNSGFALDMEERNCTD-IDECRISPDLCGSGICVNTPGSFECECFEGYESGFMM 1152
S+ C CN G+ + C+D IDEC SP L G C++ ++C C G SG
Sbjct: 589 DSYTCICNPGYMGAI----CSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGV-- 640
Query: 1153 MKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC-VDINECSLSDNL 1210
NC ++ D+C NP C G C++ + C C G + + C +DI+EC + N
Sbjct: 641 --NCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF----TGQRCNIDIDEC--ASNP 690
Query: 1211 CRNG-KCVNMIGTYQCSCNPGYQATPDRQGC-TDIDECMIMNGGCDTQCTNSEGSYECSC 1268
CR G C+N + ++C C G P C + ++EC + N CT Y+C C
Sbjct: 691 CRKGATCINGVNGFRCICPEG----PHHPSCYSQVNEC-LSNPCIHGNCTGGLSGYKCLC 745
Query: 1269 SEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
G+ G +C D +EC +NP +GG C N+ YRC C GF ++++
Sbjct: 746 DAGWV----GINCEVDKNECLSNP-CQNGGTCDNLVNGYRCTCKKGFKG---YNCQVNID 797
Query: 1328 ECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1386
EC SN C+ G C + + CHC L Y+ K C V + C+ A C
Sbjct: 798 EC--ASNPCLNQGTCFDDISGYTCHCVLPYTGK----NCQTV-LAPCSPNPCENAAVCKE 850
Query: 1387 IPG--SFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD 1443
P S+ C C GW G +C ID+DEC + C + C NT GSY C C GF+
Sbjct: 851 SPNFESYTCLCAPGW--QGQRCTIDIDECI--SKPCMNHGLCHNTQGSYMCECPPGFS-- 904
Query: 1444 GFTC-SDVDECAENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNI 1500
G C D+D+C N C+N G C++ + C C GFT CQ D++EC +
Sbjct: 905 GMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPC 958
Query: 1501 CVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVN-GLCVNTPGRYECNC 1558
GTC++ + C C G++ G +C +I+EC + +C N G CV+ + C C
Sbjct: 959 KNGGTCSDYVNSYTCKCQAGFD----GVHCENNINECTES-SCFNGGTCVDGINSFSCLC 1013
Query: 1559 PPDFQLNPTGVGCVDNRVGNC----YLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAW 1614
P F TG C+ + + C L G DG + +G + +C +
Sbjct: 1014 PVGF----TGSFCL-HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCS 1068
Query: 1615 GNPCE---TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQE---LPGLCQ-GGNCI 1667
+PC+ TC E LCP G + + DI + + LCQ G CI
Sbjct: 1069 RSPCKNKGTCVQ-KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
Query: 1668 NTFGSFQCECPQGYYLSEDTRICED-IDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQV 1726
N + C+CP GY S CE+ +DEC ++P G TC + +G Y C C P Y V
Sbjct: 1128 NAGNTHYCQCPLGYTGS----YCEEQLDECASNPCQHG-ATCSDFIGGYRCECVPGYQGV 1182
Query: 1727 NGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAD 1786
N + + + C NG TC ++ C CP PGT
Sbjct: 1183 NCEYEVDECQNQPC---QNGGTC-----IDLVNHFKC--------------SCP-PGTRG 1219
Query: 1787 FKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLL 1846
+C +ID+C P G C+++IG + C C GF+
Sbjct: 1220 L--LCEE--------------NIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER--- 1260
Query: 1847 VCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH 1905
CE DI+EC + + + DCI Y C C + F C +VC
Sbjct: 1261 -CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF---------TGRHCETFVDVCP- 1309
Query: 1906 GLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTC---KNTVGSYNCLCYPG 1962
Q C NG GTC N + C C PG
Sbjct: 1310 ----------QMPCLNG-----------------------GTCAVASNMPDGFICRCPPG 1336
Query: 1963 FELTHNNDCLDIDECSSFFGQV-CRNG-RCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC 2020
F C S GQV CR G +C + +C C P ++C + C
Sbjct: 1337 FSGA---------RCQSSCGQVKCRKGEQCVHTASGPRCFC-------PSPRDC--ESGC 1378
Query: 2021 VALP----GSCSPGTCQNLEGSFRCICPPGY 2047
+ P GSC P Q + C C P +
Sbjct: 1379 ASSPCQHGGSCHP---QRQPPYYSCQCAPPF 1406
Score = 400 bits (1028), Expect = e-110
Identities = 406/1452 (27%), Positives = 585/1452 (40%), Gaps = 305/1452 (21%)
Query: 505 CLNGRCIPTVS--SYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCH 561
CLNG +S +Y C C +G+ +C D C S+PC NG C + CKC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGF---TGKECQWTDACLSHPCANGSTCTTVANQFSCKCL 171
Query: 562 AGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDE 620
GF T Q C D++EC G G C+N GS+QC C GF G+ C
Sbjct: 172 TGF----TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYV 223
Query: 621 CTTTNMCLNGMCINEDG--SFKCICKPGFVLA---------PN----------------- 652
+ C+NG + G +F+C C PGF + PN
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283
Query: 653 --------GRYCT-DVDEC-QTPGICMN-GHCINSEGSFRCDCPPG-----LAVGMDGRV 696
G++CT DVDEC P C N G C N G + C C G + +D
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCA 343
Query: 697 CVDTHMRSTCYGGIKKGVCVRPFPGA---VTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
STC + C+ P A + C +NP + G C P + ++
Sbjct: 344 FASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHK-GALCDTNPL--NGQYI 400
Query: 754 GLCSSGVGITVDGRDINECAL-DPDICAN-GICENLRGSYRCNCNSGYEPDASGRNC-ID 810
C G D++ECA+ + + C + G C N G++ C C GY +G C +D
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----AGPRCEMD 456
Query: 811 IDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPCV-NGACR 867
I+EC + C N C + G ++C C PG+ + CE +INEC+SNPCV NG C
Sbjct: 457 INECHSDP--CQNDATCLDKIGGFTCLCMPGF----KGVHCELEINECQSNPCVNNGQCV 510
Query: 868 NNLGSFNCECSPGSKLSSTGLIC---IDSLKGTCWLNIQDSRCEVNINGATLKSEC-CAT 923
+ + F C C PG TG +C ID T LN ++C + NG EC CAT
Sbjct: 511 DKVNRFQCLCPPG----FTGPVCQIDIDDCSSTPCLN--GAKCIDHPNG----YECQCAT 560
Query: 924 --LGAAWGSPCERCELDTA----CPRGL--------ARIKGVTCED-VNECEVFPGVCPN 968
G + C+ D C G+ G C D ++EC P C N
Sbjct: 561 GFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP--CLN 618
Query: 969 -GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV-PGKFRMDACC 1026
GRC++ + C C GT V +I + C + CIH + +C
Sbjct: 619 DGRCIDLVNGYQCNCQ-----PGTSGVNCEINFDDC----ASNPCIHGICMDGINRYSCV 669
Query: 1027 CAVGAAWGTEC----EECPK----------PGTKEYETLCPRGAGFANRGDVLTGRPFYK 1072
C+ G G C +EC G + +CP G + Y
Sbjct: 670 CSPGFT-GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS---------CYS 719
Query: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPDLCGSGIC 1131
+NEC + P C +G C + +KC C++G+ NC D +EC +P G G C
Sbjct: 720 QVNECLSNP--CIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNECLSNPCQNG-GTC 772
Query: 1132 VNTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 1190
N + C C +G++ NC ++IDEC NP L GTC + + C C L +
Sbjct: 773 DNLVNGYRCTCKKGFKG-----YNCQVNIDECASNPCL-NQGTCFDDISGYTCHCVLPY- 825
Query: 1191 LSPSREDCVDINECSLSDNLCRNG---KCVNMIGTYQCSCNPGYQATPDRQGCT-DIDEC 1246
+ ++C + S N C N K +Y C C PG+Q Q CT DIDEC
Sbjct: 826 ---TGKNCQTV-LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG----QRCTIDIDEC 877
Query: 1247 M---IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNI 1302
+ MN G C N++GSY C C G++ G C DID+C NP +GG C +
Sbjct: 878 ISKPCMNHGL---CHNTQGSYMCECPPGFS----GMDCEEDIDDCLANP-CQNGGSCMDG 929
Query: 1303 PGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGT 1362
+ CLC GF K D+NEC L+ G C + S+ C CQ G+ G
Sbjct: 930 VNTFSCLCLPGFTGD---KCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFD---GV 982
Query: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCI-DLDECSNGTHQCSI 1421
+++EC +C +C++ SF C C G+ G+ C+ +++ECS +H C
Sbjct: 983 HCENNINECT--ESSCFNGGTCVDGINSFSCLCPVGFTGS--FCLHEINECS--SHPCLN 1036
Query: 1422 NAQCVNTPGSYRCACSEGFTGDG----------FTCSDVDEC----AENINLC------- 1460
CV+ G+YRC+C G+TG C + C AE+ LC
Sbjct: 1037 EGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGA 1096
Query: 1461 -------------------------ENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
+G C+N + C+C +G+T S + +DEC
Sbjct: 1097 YCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT---GSYCEEQLDEC 1153
Query: 1496 SFQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCT-DIDECADPINCVNGLCVNTPGR 1553
+ N C G TC++ G + C C GY+ G NC ++DEC + G C++
Sbjct: 1154 A-SNPCQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQNQPCQNGGTCIDLVNH 1208
Query: 1554 YECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIG-------VGVSRSSC 1606
++C+CPP G+ C +N + +C GP C IG G + C
Sbjct: 1209 FKCSCPP----GTRGLLCEEN-IDDC--ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Query: 1607 CCSLGKAWGNPCE---TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG 1663
+ + NPC + + T Y LC F +D C ++P L G
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDY-LCVCRSAFTGRHCETF---VDVCPQMPCL-NG 1316
Query: 1664 GNCI---NTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCIC 1719
G C N F C CP G+ + C + C G C +T C C
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGPRCFC 1368
Query: 1720 PPEYMQVNG--------GHNCMDMRK-----SFCYRSYNGTTCE-NELPFNVTKRMCCCT 1765
P +G G +C R+ C ++G+ CE P + C
Sbjct: 1369 PSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 1766 YNVGKAWNKPCE 1777
Y KA + C+
Sbjct: 1429 YCADKARDGVCD 1440
Score = 393 bits (1010), Expect = e-108
Identities = 382/1369 (27%), Positives = 546/1369 (39%), Gaps = 309/1369 (22%)
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELD 1524
C P A+ +C G+ P C + +CV T +N G +C C +G+
Sbjct: 18 CCAAP-AHALQCRDGYEP------------CVNEGMCV--TYHN--GTGYCKCPEGF--- 57
Query: 1525 RTGGNCTDIDECADPINCVNG-LCVNTP--GRYECNCPPDFQLNPTGVGCVDNRVGNCYL 1581
G C D C + C NG CV G+ C C F TG C + C++
Sbjct: 58 -LGEYCQHRDPC-EKNRCQNGGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFV 111
Query: 1582 KFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRP 1641
S C + G TC ++ Y C G +
Sbjct: 112 ----------------------SRPCLNGG--------TCHMLSRDTYECTCQVGFTGKE 141
Query: 1642 NPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHP 1700
T D C P G C F C+C G+ + CE D++EC P
Sbjct: 142 CQWT------DACLSHP-CANGSTCTTVANQFSCKCLTGFTGQK----CETDVNECDI-P 189
Query: 1701 GVCGPG-TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
G C G TC N G+Y C CP + + G C++
Sbjct: 190 GHCQHGGTCLNLPGSYQCQCP---------------------QGFTGQYCDSLYV----- 223
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPG------TADFKTICGNIPGFTFDIHTGKAVD--IDE 1811
PC P P T DF C +PGF G + ID+
Sbjct: 224 ---------------PCAPSPCVNGGTCRQTGDFTFECNCLPGFE-----GSTCERNIDD 263
Query: 1812 CKEIPGICANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINS 1870
C C NG VC++ + ++ C CP ++ ED+DEC N CQ C N
Sbjct: 264 CPNHR--CQNGGVCVDGVNTYNCRCPPQWTGQ---FCTEDVDECLLQPNACQNGGTCANR 318
Query: 1871 PGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQT 1930
G Y C C G+ C + + + C+D S+ C+C G KA
Sbjct: 319 NGGYGCVCVNGWS---GDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG-KAG---L 371
Query: 1931 MCMDVDECERHPCGNGTCKNTV---GSYNCLCYPGFELTHNNDCL-DIDECSSFFGQVCR 1986
+C D C +PC G +T G Y C C G++ DC D+DEC+ C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYK---GADCTEDVDECAMANSNPCE 428
Query: 1987 N-GRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICP 2044
+ G+C N G+F C C +GY G C +D NEC + P + TC + G F C+C
Sbjct: 429 HAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPCQ-NDATCLDKIGGFTCLCM 483
Query: 2045 PGYEVKSENC-IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFV-------LSD----- 2091
PG+ K +C ++INEC +P + G C + FQCLCPPGF + D
Sbjct: 484 PGF--KGVHCELEINECQSNPCVNN-GQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP 540
Query: 2092 --NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEV 2149
NG +C D + +C F C + DPC D +
Sbjct: 541 CLNGAKCIDHPNGY--------ECQCATGFTGV----LCEENIDNCDPDPCHHGQCQDGI 588
Query: 2150 -AFQDLCPYGH-GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYT 2207
++ +C G+ G + S + ++EC SP + ++G+CI+ ++C C G +
Sbjct: 589 DSYTCICNPGYMGAICS-----DQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTS---- 638
Query: 2208 GVRC-VDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAF 2266
GV C ++ D+C+ NPC +G C + I + C C+ GF G N DI+ECA NP
Sbjct: 639 GVNCEINFDDCA-SNPCIHGICMDGINRYSCVCSPGFT-GQRCNI-DIDECASNPCRKGA 695
Query: 2267 RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM---CKNLIGTFMCIC 2323
C+N + C CP G C +++C S + C + + C+C
Sbjct: 696 TCINGVNGFRCICPEG----------PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLC 745
Query: 2324 PPGMARRPDGEGC-VDENECRTKPGICENG-RCVNIIGSYRCECNEGFQSSSSGT---EC 2378
G G C VD+NEC + P C+NG C N++ YRC C +GF+ + EC
Sbjct: 746 DAGWV----GINCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC 799
Query: 2379 LDN---RQGLCFAEVLQTICQ--MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 2433
N QG CF ++ C + + +N T C C+ P Y
Sbjct: 800 ASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK--ESPNFESY 857
Query: 2434 KKICPHGPGYTTDGRDIDECKVMPNLCTN-GQCINTMGSFRCFCKVGYTTDISGTSCI-D 2491
+C G DIDEC P C N G C NT GS+ C C G+ SG C D
Sbjct: 858 TCLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECPPGF----SGMDCEED 911
Query: 2492 LDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNT 2550
+D+C +P C + ++ C C G+ G C+ D++EC ++ C +
Sbjct: 912 IDDCLANPCQNGGSCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDY 967
Query: 2551 LGGFTCKCPPGFTQHHTACIDN-NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATG 2609
+ +TCKC GF H C +N NEC S C G C + SFSC C GF TG
Sbjct: 968 VNSYTCKCQAGFDGVH--CENNINECTE--SSCFNGGTCVDGINSFSCLCPVGF----TG 1019
Query: 2610 LNC-EDVDECDGNHRCQHG-CQNILGGYRCGCPQGY-----------------------I 2644
C +++EC + G C + LG YRC CP GY +
Sbjct: 1020 SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCV 1079
Query: 2645 QHYQWNQCVDENE-----CSNPN-ACGSAS----------------CYNTLGSYKCACPS 2682
Q +QC+ + C PN +C A+ C N ++ C CP
Sbjct: 1080 QKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPL 1139
Query: 2683 GFSFDQFSSACHD-VNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYRV 2728
G++ S C + ++EC+S NPC +G CS+ GGY C C PGY V
Sbjct: 1140 GYT----GSYCEEQLDECAS--NPCQHGATCSDFIGGYRCECVPGYQGV 1182
Score = 347 bits (891), Expect = 8e-95
Identities = 366/1332 (27%), Positives = 522/1332 (39%), Gaps = 289/1332 (21%)
Query: 104 LPGGNQC--------------IVPICRNSCGDGFCSRPN-----MCTCSSGQISSTCGSK 144
LPG QC VP + C +G R C C G STC +
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC-ER 259
Query: 145 SIQQC-SVRCMNGGTCADD----HCQCQKGYIGTYCGQPVCE-----NGCQNGGRCIGPN 194
+I C + RC NGG C D +C+C + G +C + V E N CQNGG C N
Sbjct: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN 319
Query: 195 R---CACVYGFTGPQCERDYRT---------GPCFTQVNNQ--MCQGQLTGIVCTKTLCC 240
C CV G++G C + C +V + MC G++C C
Sbjct: 320 GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDAC 379
Query: 241 ATIGRAWGHPCEMCPAQPQ---PCRRGFIPNIRTGAC-QDVDEC-QAIPGICQ-GGNCIN 294
+ G C+ P Q C +G+ + C +DVDEC A C+ G C+N
Sbjct: 380 ISNPCHKGALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVN 435
Query: 295 TVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTS 352
T G+F C C G+ +CE DI+EC P C+ C + +G + C+C G+
Sbjct: 436 TDGAFHCECLKGY----AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGF--- 486
Query: 353 TDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGS 410
G C + C S + NG+C ++ + QC C P G C +
Sbjct: 487 -KGVHC-ELEINECQSNPCVNNGQCVD----KVNRFQCLCPP------GFTGPVCQIDID 534
Query: 411 EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF--- 467
+ C++G P + TG G N + P G
Sbjct: 535 DCSSTPCLNGAKCIDHPNGYECQCA-TGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593
Query: 468 --SPGVGGA---------------------GVGAGGQGPIITGLTILNQTIDICKHHANL 504
+PG GA + G Q G + +N I+ +N
Sbjct: 594 ICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP 653
Query: 505 CLNGRCIPTVSSYRCECNMGYK-QDANGDCIDVDECTSNPCTNG-DCVNTPGSYYCKCHA 562
C++G C+ ++ Y C C+ G+ Q N ID+DEC SNPC G C+N + C C
Sbjct: 654 CIHGICMDGINRYSCVCSPGFTGQRCN---IDIDECASNPCRKGATCINGVNGFRCICPE 710
Query: 563 GFQRTPTKQACI-DIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDE 620
G P +C ++EC+ N C +G C ++C+C+AG+ G NC VD +E
Sbjct: 711 G----PHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNE 760
Query: 621 CTTTNMCLN-GMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEG 678
C +N C N G C N ++C CK GF G C ++DEC + G C +
Sbjct: 761 C-LSNPCQNGGTCDNLVNGYRCTCKKGF----KGYNCQVNIDECASNPCLNQGTCFDDIS 815
Query: 679 SFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFG 738
+ C CV P+ G ++
Sbjct: 816 GYTCH-------------------------------CVLPYTGKNCQTVLA--------- 835
Query: 739 EPCQPCPAKNSA---------EFHGLCSSGVGITVDGRDINECALDPDICAN-GICENLR 788
PC P P +N+A + LC+ G DI+EC P C N G+C N +
Sbjct: 836 -PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQ 892
Query: 789 GSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTE 846
GSY C C G+ SG +C DID+CL N C N G C + ++SC C PG+ T
Sbjct: 893 GSYMCECPPGF----SGMDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGF---TG 943
Query: 847 TETCEDINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDS 905
+ D+NEC S PC N G C + + S+ C+C G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG---------------------FDGV 982
Query: 906 RCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTC-EDVNECEVFPG 964
CE NIN T +S C G C CP G G C ++NEC P
Sbjct: 983 HCENNINECT-ESSCFNGGTCVDGINSFSC----LCPVGFT---GSFCLHEINECSSHP- 1033
Query: 965 VCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLK--WDEDECIHPVPGKFR 1021
C N G CV+ G++ C CP G TG+ C + + C ++ C+ K
Sbjct: 1034 -CLNEGTCVDGLGTYRCSCPLGY----TGKNCQTL-VNLCSRSPCKNKGTCVQ----KKA 1083
Query: 1022 MDACCCAVGAAWGTECE----ECPKPGTKE---YETLCPRGAGFANRGDV--------LT 1066
C C G A G C+ C ++ E LC N G+ T
Sbjct: 1084 ESQCLCPSGWA-GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
Query: 1067 GRPFYKDINECKAFPGMCTYG-KCRNTIGSFKCRCNSGFALDMEERNCT-DIDECRISPD 1124
G + ++EC + P C +G C + IG ++C C G+ + NC ++DEC+ P
Sbjct: 1143 GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPC 1196
Query: 1125 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCD 1184
G G C++ F+C C G G + +N ID+C R P GG C++ G + C
Sbjct: 1197 QNG-GTCIDLVNHFKCSCPPG-TRGLLCEEN---IDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 1185 CPLGHELSPSREDCV-DINECSLSDNLCRNGK--CVNMIGTYQCSCNPGYQATPDRQGCT 1241
C G + E C DINEC LS+ G C+ + Y C C + R T
Sbjct: 1252 CLPGF----AGERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTG---RHCET 1303
Query: 1242 DIDECMIM---NGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQ 1298
+D C M NGG +N + C C G++ SC + +C G Q
Sbjct: 1304 FVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV-KCRK------GEQ 1356
Query: 1299 CTNIPGEYRCLC 1310
C + RC C
Sbjct: 1357 CVHTASGPRCFC 1368
Score = 338 bits (868), Expect = 4e-92
Identities = 377/1415 (26%), Positives = 552/1415 (39%), Gaps = 300/1415 (21%)
Query: 79 QQDVLRGPNVCGSRFHSY---CCPGWK--------------TLPGGNQCIVPICRNSCGD 121
Q + + C +R Y C GW + G+ CI + SC
Sbjct: 305 QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364
Query: 122 GFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCE 181
+C IS+ C ++ C +NG C C +GY G C + V E
Sbjct: 365 PEGKAGLLCHLDDACISNPCHKGAL--CDTNPLNGQYI----CTCPQGYKGADCTEDVDE 418
Query: 182 ------NGCQNGGRCI---GPNRCACVYGFTGPQCERDY---RTGPCFTQVNNQMCQGQL 229
N C++ G+C+ G C C+ G+ GP+CE D + PC N+ C ++
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPC---QNDATCLDKI 475
Query: 230 TGIVC------TKTLCCATIGRAWGHPC---EMCPAQPQPCRRGFIPNIRTGACQ-DVDE 279
G C C I +PC C + + P CQ D+D+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD 535
Query: 280 CQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED-IDECSIIPGICETGECSNTV 338
C + P + G CI+ +EC+C G T CE+ ID C P C G+C + +
Sbjct: 536 CSSTPCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHHGQCQDGI 588
Query: 339 GSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMTKMQCCCEPGRCW 396
SY C+C GY+ G+ C DQ C+S L +GRC + G QC C+P
Sbjct: 589 DSYTCICNPGYM----GAICSDQ-IDECYSSPCLNDGRCIDLVNG----YQCNCQP---- 635
Query: 397 GIGTIPEACPVRGSEEYRRLCMDGLPMGGIPG-SAGSRPGGTGGNGFAPSGNGNGYGPGG 455
GT C + + C+ G+ M GI S PG TG + P
Sbjct: 636 --GTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDI-DECASNPCR 692
Query: 456 TGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVS 515
G I G NGF G P + + +N+ + +N C++G C +S
Sbjct: 693 KGATCINGVNGFR-----CICPEGPHHP--SCYSQVNECL------SNPCIHGNCTGGLS 739
Query: 516 SYRCECNMGYKQDANGDC-IDVDECTSNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQAC 573
Y+C C+ G+ +C +D +EC SNPC N G C N Y C C GF+ +
Sbjct: 740 GYKCLCDAGW---VGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ--- 793
Query: 574 IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCI 633
++IDEC N L G C + + C C L GKNC + N C N
Sbjct: 794 VNIDECASNPCL-NQGTCFDDISGYTCHC----VLPYTGKNCQTVLAPCSPNPCENAAVC 848
Query: 634 NEDGSFK---CICKPGFVLAPNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLA 689
E +F+ C+C PG+ G+ CT D+DEC + +G C N++GS+ C+CPPG +
Sbjct: 849 KESPNFESYTCLCAPGW----QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 690 VGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF-GEPCQPCPAKN 748
GMD +D + + C G G C+ V C C GF G+ CQ
Sbjct: 905 -GMDCEEDIDDCLANPCQNG---GSCM----DGVNTFSCLCLP---GFTGDKCQ------ 947
Query: 749 SAEFHGLCSSGVGITVDGRDINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRN 807
D+NEC +P C N G C + SY C C +G++ G +
Sbjct: 948 ------------------TDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFD----GVH 983
Query: 808 C-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GA 865
C +I+EC + + G C + S+SC CP G+ T + +INEC S+PC+N G
Sbjct: 984 CENNINECTESSCF-NGGTCVDGINSFSCLCPVGF---TGSFCLHEINECSSHPCLNEGT 1039
Query: 866 CRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLG 925
C + LG++ C C L TG C +L C S C+ K+E
Sbjct: 1040 CVDGLGTYRCSC----PLGYTGKNC-QTLVNLC----SRSPCKNKGTCVQKKAESQCLCP 1090
Query: 926 AAW-GSPCE--RCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCEC 982
+ W G+ C+ D A R +GV E + C+ +G C+N+ + +C+C
Sbjct: 1091 SGWAGAYCDVPNVSCDIAASR-----RGVLVEHL--CQ------HSGVCINAGNTHYCQC 1137
Query: 983 PEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVP-----GKFRMDACCCAVGAAWGTEC 1037
P G TG C + ++++C + C H G +R C C G G C
Sbjct: 1138 PLGY----TGSYC-EEQLDEC----ASNPCQHGATCSDFIGGYR---CECVPGYQ-GVNC 1184
Query: 1038 E---------ECPKPGT-----KEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM 1083
E C GT ++ CP G G ++I++C P
Sbjct: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGT---------RGLLCEENIDDCARGPHC 1235
Query: 1084 CTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP-DLCGSGICVNTPGSFECEC 1142
G+C + IG + CRC GFA ER DI+EC +P GS C+ + C C
Sbjct: 1236 LNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Query: 1143 FEGYESGFMMMKNCMD-IDECERNPLLCRGGTCV---NTEGSFQCDCPLGHELSPSREDC 1198
+ ++C +D C + P L GGTC N F C CP G + + C
Sbjct: 1293 RSAFTG-----RHCETFVDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Query: 1199 VDINECSLSDNLCRNG-KCVNMIGTYQC------SCNPGYQATPDRQGCTDIDECMIMNG 1251
+ CR G +CV+ +C C G ++P + G G
Sbjct: 1347 GQVK--------CRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHG-----------G 1387
Query: 1252 GCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNP----------DICDGGQCTN 1301
C Q Y C C+ ++ G C + P D G C
Sbjct: 1388 SCHPQ--RQPPYYSCQCAPPFS----GSRCELYTAPPSTPPATCLSQYCADKARDGVCDE 1441
Query: 1302 IPGEYRCLCYDGFMASMDMKT----------CIDV--NECD--LNSNICMFGECENTKGS 1347
+ C +DG S+ M+ C D N+CD N+ C+F E S
Sbjct: 1442 ACNSHACQ-WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS 1500
Query: 1348 FIC----HCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
C +C + GC +EC +C
Sbjct: 1501 KTCKYDKYCADHFKDNHCDQGCNS-EECGWDGLDC 1534
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 473 bits (1218), Expect = e-133
Identities = 464/1657 (28%), Positives = 663/1657 (40%), Gaps = 344/1657 (20%)
Query: 1123 PDLCGSGICVNTPGSF-----ECECFEGYES----GFMMMKNCMDIDECERNPLLCRG-G 1172
P L G + PG +CE G E+ G + C D + C P C+ G
Sbjct: 15 PALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTP--CKNAG 72
Query: 1173 TC--VNTEG--SFQCDCPLGHE----LSPSREDCVDINECSLSDNLCRNGKCVNMIGT-- 1222
TC V+ G + C C LG L+P C+ N CRNG +++
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLT--------NPCRNGGTCDLLTLTE 124
Query: 1223 YQCSCNPGYQATPDRQGCTDIDECM---IMNGGCDTQCTNSEGSYECSCSEGYALMPDGR 1279
Y+C C PG+ + C D C NGG QC E SY C C + G
Sbjct: 125 YKCRCPPGWSG----KSCQQADPCASNPCANGG---QCLPFEASYICHCPPSF----HGP 173
Query: 1280 SCA-DIDECENNPDIC-DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM 1337
+C D++EC P +C GG C N G YRC+C + + + +
Sbjct: 174 TCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG--- 230
Query: 1338 FGECENTKG-SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCR 1396
G C T + C C G++ G ++D+C +NC +C++ ++ C C
Sbjct: 231 -GTCRPTGDVTHECACLPGFT---GQNCEENIDDCP--GNNCKNGGACVDGVNTYNCRCP 284
Query: 1397 EGWIGNGIKCI-DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE 1455
W G C D+DEC + C C NT G Y C C G+TG ++C+E
Sbjct: 285 PEWTGQ--YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTG--------EDCSE 334
Query: 1456 NINLCENGQCLNVP------GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGT-CNN 1508
NI+ C + C + ++ CEC G T C D C N C G+ C+
Sbjct: 335 NIDDCASAACFHGATCHDRVASFYCECPHGRT----GLLCHLNDAC-ISNPCNEGSNCDT 389
Query: 1509 LP--GMFHCICDDGYELDRTGGNCT-DIDECADPIN-CVN-GLCVNTPGRYECNCPPDFQ 1563
P G C C GY TG C+ D+DEC+ N C + G C+NT G +EC C +
Sbjct: 390 NPVNGKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT 445
Query: 1564 LNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE---T 1620
GPR C ++ VS NPC+ T
Sbjct: 446 --------------------GPR------CEIDVNECVS-------------NPCQNDAT 466
Query: 1621 CPPVNSTEYYTLC-PGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQ 1679
C E+ +C PG EG T DEC P L G C++ FQCECP
Sbjct: 467 CLD-QIGEFQCICMPGYEGVHCEVNT------DECASSPCL-HNGRCLDKINEFQCECPT 518
Query: 1680 GYYLSEDTRICE-DIDECFAHPGVCGPGT-CYNTLGNYTCICPPEYMQVNGGHNCMDMRK 1737
G+ +C+ D+DEC + P C G C + YTC+C Y G H +D+ +
Sbjct: 519 GF----TGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDE 569
Query: 1738 SFCYRSYNGTTCENELPFNVTKRMCC----CTYNVGKAWNKPCEPCPTPGTADFKTICGN 1793
+ G+ + F R C N+ + ++PC T D +C
Sbjct: 570 CDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFC 629
Query: 1794 IPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCE-DID 1852
+ G T +++D+C P C +G C+++I + C C G++ + +C +ID
Sbjct: 630 LKGTT---GPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGS----MCNINID 680
Query: 1853 ECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDR-NECLEIPNVCSHGLCVDL 1911
EC+ N C C + + C C G+ + C+ NEC N C HG C D
Sbjct: 681 ECAG--NPCHNGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNS--NPCVHGACRDS 733
Query: 1912 QGSYQCICHNGFKASQDQTMC-MDVDECERHPCGN-GTCKNTVGSYNCLCYPGFELTHNN 1969
Y+C C G+ T C ++ +ECE +PC N GTCK+ Y C C GF + N
Sbjct: 734 LNGYKCDCDPGWSG----TNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF--SGPN 787
Query: 1970 DCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCS 2028
+I+EC+S C N G C +++ +KC C Y G C E V P + S
Sbjct: 788 CQTNINECAS---NPCLNQGTCIDDVAGYKCNCLLPY----TGATC----EVVLAPCAPS 836
Query: 2029 P----GTCQNLEG--SFRCICPPGYEVKSENC-IDINECDEDPNICLFG-SCTNTPGGFQ 2080
P G C+ E SF C+CP G++ + C +DINEC P C G SC NT GG++
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQ--GQTCEVDINECVLSP--CRHGASCQNTHGGYR 892
Query: 2081 CLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPC 2140
C C G+ +GR C T+ ++ C P G
Sbjct: 893 CHCQAGY----SGRN--------CETDIDD-----------------CRPNPCHNGGS-- 921
Query: 2141 ELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG-QCINTDGSFRCECP 2199
C AF D P GT ED+NEC P C NG C + S+ C CP
Sbjct: 922 --CTDGINTAFCDCLPGFRGTF-----CEEDINECASDP--CRNGANCTDCVDSYTCTCP 972
Query: 2200 MGYNLDYTGVRCV-DTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECA 2258
G ++G+ C +T +C+ + GTC + I SF C C GF + D+NEC
Sbjct: 973 AG----FSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH--DVNECD 1026
Query: 2259 QNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCES----RGMMCKN 2314
P L C + GSY CTCP GY C +H C+S G C
Sbjct: 1027 SQPCLHGGTCQDGCGSYRCTCPQGYT----------GPNCQNLVHWCDSSPCKNGGKCWQ 1076
Query: 2315 LIGTFMCICPPGMARRPDGEGCVDENECRTKPGI-----CEN-GRCVNIIGSYRCECNEG 2368
+ C CP G V + G+ C++ G CV+ ++ C C G
Sbjct: 1077 THTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1136
Query: 2369 FQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLP 2428
+ +G+ C D E + CQ ++ + + C C G
Sbjct: 1137 Y----TGSYCED-----LVDECSPSPCQNGATCTDYLGGYSCKCVAGY------------ 1175
Query: 2429 GTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTN-GQCINTMGSFRCFCKVGYTTDISGT 2487
HG +IDEC P C N G C++ +++C C G G
Sbjct: 1176 ----------HG---VNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRG----TQGV 1216
Query: 2488 SC-IDLDEC-------SQSPKPC--NYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDEC 2536
C I++D+C S+SPK C N C + G Y C+CP G+V G+ C+ D++EC
Sbjct: 1217 HCEINVDDCNPPVDPVSRSPK-CFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNEC 1271
Query: 2537 QTKQHNCQFL--CVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGS 2594
+ + + CV + F C+C G T + N G G + NT
Sbjct: 1272 LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG 1331
Query: 2595 FSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILG--GYRCGCPQGY----IQHYQ 2648
F C+C GF G CE+ G+ RC +G I G C C + Q
Sbjct: 1332 FICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA 1387
Query: 2649 WNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFS 2685
+ C+ N C N C S Y+C CP+ F+
Sbjct: 1388 SSPCLGGNPCYNQGTCEPTS---ESPFYRCLCPAKFN 1421
Score = 462 bits (1189), Expect = e-129
Identities = 429/1487 (28%), Positives = 602/1487 (40%), Gaps = 343/1487 (23%)
Query: 1412 CSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCEN-GQCLNVP- 1469
CS C +C G+ C C F G C D + C C+N G C V
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGP--RCQDPNPCLSTP--CKNAGTCHVVDR 79
Query: 1470 ---GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFG-TCNNLP-GMFHCICDDGYELD 1524
Y C C +GF S +D N C G TC+ L + C C G+
Sbjct: 80 RGVADYACSCALGF---SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW--- 133
Query: 1525 RTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFG 1584
+G +C D CA G C+ Y C+CPP F G C + V C K G
Sbjct: 134 -SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH----GPTCRQD-VNECGQKPG 187
Query: 1585 PRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGN-----------PCE---TCPPVNSTEYY 1630
G +C+ E+G C C N PC+ TC P +
Sbjct: 188 LCRHGG-TCHNEVG----SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHE 242
Query: 1631 TLC-PGGEGFRPNPITIILEDIDECQELPGL-CQ-GGNCINTFGSFQCECPQ---GYYLS 1684
C PG G E+ID+C PG C+ GG C++ ++ C CP G Y +
Sbjct: 243 CACLPGFTGQNCE------ENIDDC---PGNNCKNGGACVDGVNTYNCRCPPEWTGQYCT 293
Query: 1685 EDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRS 1743
ED +DEC P C GTC+NT G Y C+C + + N D + C+
Sbjct: 294 ED------VDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF-- 345
Query: 1744 YNGTTCEN-------ELPFNVTKRMC-----CCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
+G TC + E P T +C C + + N C+ P G K IC
Sbjct: 346 -HGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSN--CDTNPVNG----KAIC 398
Query: 1792 GNIPGFTFDIHTGKAV--DIDECKEIPGICAN-GVCINQIGSFRCECPTGFSYNDLLLVC 1848
G+T G A D+DEC C + G CIN +GSF C+C G++ C
Sbjct: 399 TCPSGYT-----GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR----C 449
Query: 1849 E-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGAC-VDRNECLEIPNVCSH- 1905
E D++EC + N CQ +A C++ G ++C C G++ C V+ +EC P C H
Sbjct: 450 EIDVNECVS--NPCQNDATCLDQIGEFQCICMPGYE---GVHCEVNTDECASSP--CLHN 502
Query: 1906 GLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGT-CKNTVGSYNCLCYPGFE 1964
G C+D +QC C GF Q DVDEC PC NG C + +Y C+C G+
Sbjct: 503 GRCLDKINEFQCECPTGFTGHLCQ---YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT 559
Query: 1965 LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVAL 2023
TH +DIDEC C G C + + +F CLC GY G +C + NEC +
Sbjct: 560 GTHCE--VDIDECDP---DPCHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQ 610
Query: 2024 PGSCSPGTCQNLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLFGSCTNTPGGFQCL 2082
P GTCQ+ + ++ C C G NC I++++C P C G+C + G++C
Sbjct: 611 PCRHG-GTCQDRDNAYLCFCLKG--TTGPNCEINLDDCASSP--CDSGTCLDKIDGYECA 665
Query: 2083 CPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCEL 2142
C PG+ S C N + C+ P G CE
Sbjct: 666 CEPGYT------------GSMCNINIDE-----------------CAGNPCHN-GGTCE- 694
Query: 2143 CPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGY 2202
D F CP G+ L +VNEC +P C +G C ++ ++C+C G+
Sbjct: 695 ---DGINGFTCRCPEGYHDPTCL----SEVNECNSNP--CVHGACRDSLNGYKCDCDPGW 745
Query: 2203 NLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQ 2259
+ G C ++ +EC NPC NG TC ++ + C C EGF GP NC+ +INECA
Sbjct: 746 S----GTNCDINNNECE-SNPCVNGGTCKDMTSGYVCTCREGFS-GP--NCQTNINECAS 797
Query: 2260 NPLLCAFRCMNTFGSYECTCPIGYALREDQKM--------CKDLDECAEGLHDCESRGMM 2311
NP L C++ Y+C C + Y + + C++ EC + D ES
Sbjct: 798 NPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS-EDYES---- 852
Query: 2312 CKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENGR-CVNIIGSYRCECNEGF 2369
F C+CP G G+ C VD NEC P C +G C N G YRC C G+
Sbjct: 853 -------FSCVCPTGW----QGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY 899
Query: 2370 QSSSSGTECLDNRQGLC-----------------------------FAEVLQTICQMASS 2400
+ T+ D R C E C+ ++
Sbjct: 900 SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN 959
Query: 2401 SRNLVTKSECCCDGGRGWGHQCE---------------LCPLPGTAQYKKICPHGPGYTT 2445
+ V C C G G CE C + G + +CP PG+T
Sbjct: 960 CTDCVDSYTCTCPAGFS-GIHCENNTPDCTESSCFNGGTC-VDGINSFTCLCP--PGFTG 1015
Query: 2446 D--GRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDE-CSQSPKPC 2502
D++EC P L G C + GS+RC C GYT G +C +L C SP
Sbjct: 1016 SYCQHDVNECDSQPCL-HGGTCQDGCGSYRCTCPQGYT----GPNCQNLVHWCDSSPCKN 1070
Query: 2503 NYICKNTEGSYQCSCPRGYV------------------------LQEDGKTCKD------ 2532
C T Y+C CP G+ L + G C D
Sbjct: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
Query: 2533 ---------------LDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDN-NECG 2576
+DEC C + LGG++CKC G+ H C + +EC
Sbjct: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY--HGVNCSEEIDECL 1188
Query: 2577 SQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDG-------NHRCQHG- 2627
S P C G C + P ++ C C RG G++CE +VD+C+ + +C +
Sbjct: 1189 SHP--CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNG 1242
Query: 2628 -CQNILGGYRCGCPQGYIQHYQWNQCV-DENEC-SNP-NACGSASCYNTLGSYKCACPSG 2683
C + +GGY C CP G++ +C D NEC SNP +A G+ +C + + C C +G
Sbjct: 1243 TCVDQVGGYSCTCPPGFVGE----RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
Query: 2684 FSFDQFSSACHDVNECSSSKNPCNYG-----CSNTEGGYLCGCPPGY 2725
+ + S +N C PC G SNT G++C CP G+
Sbjct: 1299 HTGRRCESV---INGCKGK--PCKNGGTCAVASNTARGFICKCPAGF 1340
Score = 448 bits (1153), Expect = e-125
Identities = 491/1738 (28%), Positives = 683/1738 (39%), Gaps = 437/1738 (25%)
Query: 498 CKHHANLCLNG-RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTN-GDC--VNTP 553
C CLNG +C + C C + C D + C S PC N G C V+
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF---VGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
Query: 554 G--SYYCKCHAGFQ----RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFE 607
G Y C C GF TP AC+ + C +NG C + T ++C C G+
Sbjct: 81 GVADYACSCALGFSGPLCLTPLDNACL-TNPC-RNGGTCD----LLTLTEYKCRCPPGW- 133
Query: 608 LTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDEC-QTP 665
GK+C D C + G C+ + S+ C C P F +G C DV+EC Q P
Sbjct: 134 ---SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKP 186
Query: 666 GICMN-GHCINSEGSFRCDCPPGLAVGMDGRVCVDTHM---RSTCYGGIKKGVCVRPFPG 721
G+C + G C N GS+RC C G C ++ S C G G C RP G
Sbjct: 187 GLCRHGGTCHNEVGSYRCVC----RATHTGPNCERPYVPCSPSPCQNG---GTC-RP-TG 237
Query: 722 AVTKSECCCANPDYGF-GEPCQ----PCPAKNSAEFHGLCSSGVGITVDGR--------- 767
VT EC C GF G+ C+ CP N+ + G C GV T + R
Sbjct: 238 DVT-HECACLP---GFTGQNCEENIDDCPG-NNCKNGGACVDGVN-TYNCRCPPEWTGQY 291
Query: 768 ---DINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRNCID-IDECLV------ 816
D++EC L P+ C N G C N G Y C C +G+ +G +C + ID+C
Sbjct: 292 CTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHG 347
Query: 817 ------------------NRLLCD-NGLCRNTP-------------GSYSCTCPPGYVFR 844
LLC N C + P G CTCP GY
Sbjct: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--- 404
Query: 845 TETETCEDINECE--SNPCVN-GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLN 901
T +D++EC +NPC + G C N LGSF C+C G TG
Sbjct: 405 TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQG----YTG-------------- 446
Query: 902 IQDSRCEVNINGATLKSECCATLGAAWGSPCER---C-----ELDTACPRGLARIKGVTC 953
RCE+++N EC + +PC+ C E C G +GV C
Sbjct: 447 ---PRCEIDVN------ECVS-------NPCQNDATCLDQIGEFQCICMPG---YEGVHC 487
Query: 954 E-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
E + +EC P NGRC++ F CECP G TG +C ++D DEC
Sbjct: 488 EVNTDECASSP-CLHNGRCLDKINEFQCECPTGF----TGHLC----------QYDVDEC 532
Query: 1013 IHP--VPGKFRMD-----ACCCAVGAAWGTECE----ECP---------KPGTKEYETLC 1052
G +D C C G GT CE EC K G + LC
Sbjct: 533 ASTPCKNGAKCLDGPNTYTCVCTEGYT-GTHCEVDIDECDPDPCHYGSCKDGVATFTCLC 591
Query: 1053 PRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFKCRCNSGFALDMEER 1111
G TG +INEC + P C + G C++ ++ C C G
Sbjct: 592 RPG---------YTGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG----TTGP 636
Query: 1112 NC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR 1170
NC ++D+C SP C SG C++ +EC C GY +G M N IDEC NP
Sbjct: 637 NCEINLDDCASSP--CDSGTCLDKIDGYECACEPGY-TGSMCNIN---IDECAGNP-CHN 689
Query: 1171 GGTCVNTEGSFQCDCPLGHELSPSREDCV-DINECSLSDNLCRNGKCVNMIGTYQCSCNP 1229
GGTC + F C CP G+ P+ C+ ++NEC + N C +G C + + Y+C C+P
Sbjct: 690 GGTCEDGINGFTCRCPEGYH-DPT---CLSEVNEC--NSNPCVHGACRDSLNGYKCDCDP 743
Query: 1230 GYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECE 1288
G+ T + + +NGG C + Y C+C EG++ G +C +I+EC
Sbjct: 744 GWSGTNCDINNNECESNPCVNGG---TCKDMTSGYVCTCREGFS----GPNCQTNINECA 796
Query: 1289 NNPDICDGGQCTNIPGEYRCLC---YDGFMASMDMKTC---------------------- 1323
+NP + + G C + Y+C C Y G + + C
Sbjct: 797 SNPCL-NQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSC 855
Query: 1324 ------------IDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDE 1370
+D+NEC L+ C G C+NT G + CHCQ GYS G TD+D+
Sbjct: 856 VCPTGWQGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYS---GRNCETDIDD 910
Query: 1371 CEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1430
C + C SC + + C C G+ G + D++EC+ + C A C +
Sbjct: 911 CR--PNPCHNGGSCTDGINTAFCDCLPGFRGTFCE-EDINECA--SDPCRNGANCTDCVD 965
Query: 1431 SYRCACSEGFTGDGFTC-SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
SY C C GF+ G C ++ +C E+ + G C++ ++ C C GFT C
Sbjct: 966 SYTCTCPAGFS--GIHCENNTPDCTES-SCFNGGTCVDGINSFTCLCPPGFT----GSYC 1018
Query: 1490 Q-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVN-GLC 1547
Q D++EC Q GTC + G + C C GY TG NC ++ D C N G C
Sbjct: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKC 1074
Query: 1548 VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEI---GVGVSRS 1604
T +Y C CP + TG+ C S+SC GV V+R
Sbjct: 1075 WQTHTQYRCECPSGW----TGLYC---------------DVPSVSCEVAAQRQGVDVAR- 1114
Query: 1605 SCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ-G 1663
C G C +T + G G + + +DEC P CQ G
Sbjct: 1115 --LCQHG-------GLCVDAGNTHHCRCQAGYTG------SYCEDLVDECS--PSPCQNG 1157
Query: 1664 GNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEY 1723
C + G + C+C GY+ E+IDEC +HP G GTC + Y C CP
Sbjct: 1158 ATCTDYLGGYSCKCVAGYH---GVNCSEEIDECLSHPCQNG-GTCLDLPNTYKCSCPRGT 1213
Query: 1724 MQVNGGHNCMDMRK-----SFCYRSYNGTTCENEL--------PFNVTKRMCCCTYNVGK 1770
V+ N D S + +N TC +++ P V +R C +V +
Sbjct: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGER---CEGDVNE 1270
Query: 1771 AWNKPCEPCPTPGTA----DFKTICGNIPGFTFDIHTGKAVD--IDECKEIPGICANG-- 1822
+ PC+ T DF C HTG+ + I+ CK P C NG
Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECR-------AGHTGRRCESVINGCKGKP--CKNGGT 1321
Query: 1823 --VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAA 1880
V N F C+CP GF CE+ D + G C CI+ P S C C
Sbjct: 1322 CAVASNTARGFICKCPAGFEG----ATCEN-DARTCGSLRCLNGGTCISGPRSPTCLCLG 1376
Query: 1881 GF-----KLSPNGACVDRNECLEIPNVCSHGLCVDLQGS--YQCICHNGFK--------- 1924
F + + C+ N C + G C S Y+C+C F
Sbjct: 1377 PFTGPECQFPASSPCLGGNPCY------NQGTCEPTSESPFYRCLCPAKFNGLLCHILDY 1430
Query: 1925 -----ASQDQTMCMDVDECERHPC----GNGTCKNTVGSYNCLCYPGFELTHNND----C 1971
A +D + + CE C GN C ++ C G + ND C
Sbjct: 1431 SFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNC 1490
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP 2029
+C +F +G C ++ S CL D +C G C+P
Sbjct: 1491 TQSLQCWKYFS----DGHCDSQCNSAGCL--------------FDGFDCQRAEGQCNP 1530
Score = 421 bits (1082), Expect = e-117
Identities = 394/1327 (29%), Positives = 536/1327 (40%), Gaps = 264/1327 (19%)
Query: 1536 CADP-INCVNG-LCVNTPGRYECNCPPDFQLNPTGVGCVD---------NRVGNCYLKFG 1584
C+ P C+NG C G C C F G C D G C++
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHV-VD 78
Query: 1585 PRGDGSLSCNTEIGVGVSRSSCCCSLGKAW-GNPCE---TCPPVNSTEYYTLCPGGEGFR 1640
RG +C+ +G S C L A NPC TC + TEY CP G +
Sbjct: 79 RRGVADYACSCALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 1641 PNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 1700
+ D C P GG C+ S+ C CP ++ +D++EC P
Sbjct: 137 S------CQQADPCASNP-CANGGQCLPFEASYICHCPPSFH---GPTCRQDVNECGQKP 186
Query: 1701 GVCGPG-TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
G+C G TC+N +G+Y C+C + G NC E P+
Sbjct: 187 GLCRHGGTCHNEVGSYRCVCRATHT----GPNC-------------------ERPY---- 219
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPG------TADFKTICGNIPGFTFDIHTGKAVDIDECK 1813
PC P P T D C +PGFT +ID+C
Sbjct: 220 --------------VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQ---NCEENIDDC- 261
Query: 1814 EIPGI-CANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSP 1871
PG C NG C++ + ++ C CP ++ ED+DEC N CQ C N+
Sbjct: 262 --PGNNCKNGGACVDGVNTYNCRCPPEWTGQ---YCTEDVDECQLMPNACQNGGTCHNTH 316
Query: 1872 GSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCICHNGFKASQDQT 1930
G Y C C G+ +D +C C HG C D S+ C C +G +
Sbjct: 317 GGYNCVCVNGWTGEDCSENID--DCASA--ACFHGATCHDRVASFYCECPHG----RTGL 368
Query: 1931 MCMDVDECERHPCGNGTCKNTV---GSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
+C D C +PC G+ +T G C C G+ T D+DECS
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY--TGPACSQDVDECSLGANPCEHA 426
Query: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPG 2046
G+C N +GSF+C C +GY G C ID NECV+ P + TC + G F+CIC PG
Sbjct: 427 GKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNPCQ-NDATCLDQIGEFQCICMPG 481
Query: 2047 YEVKSENC-IDINECDEDPNICLF-GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFC 2104
YE +C ++ +EC P CL G C + FQC CP GF G C
Sbjct: 482 YE--GVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA 533
Query: 2105 FTNFENG-KCSVPKAFNTTKAKCC-------CSKMPGEGWGDPCELCPKDDEVA-FQDLC 2155
T +NG KC NT C C E DPC D VA F LC
Sbjct: 534 STPCKNGAKCL--DGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLC 591
Query: 2156 PYGHGTVPSLHDTREDVNECLESPGICSNG-QCINTDGSFRCECPMGYNLDYTGVRC-VD 2213
G+ + H ++NEC P C +G C + D ++ C C G TG C ++
Sbjct: 592 RPGY----TGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKGT----TGPNCEIN 641
Query: 2214 TDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFG 2273
D+C+ +PC +GTC + I +EC C G+ G M N +I+ECA NP C +
Sbjct: 642 LDDCA-SSPCDSGTCLDKIDGYECACEPGYT-GSMCNI-NIDECAGNPCHNGGTCEDGIN 698
Query: 2274 SYECTCPIGYALREDQKMCKDLDECAEG--LHDCESRGMMCKNLIGTFMCICPPGMARRP 2331
+ C CP GY D +++EC +H C++ + + C C PG +
Sbjct: 699 GFTCRCPEGY---HDPTCLSEVNECNSNPCVHGA------CRDSLNGYKCDCDPGWS--- 746
Query: 2332 DGEGC-VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT---ECLDN---RQG 2384
G C ++ NEC + P + G C ++ Y C C EGF + T EC N QG
Sbjct: 747 -GTNCDINNNECESNPCV-NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804
Query: 2385 LCFAEVLQTICQMA---SSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGP 2441
C +V C + + V + C R G E + +CP G
Sbjct: 805 TCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGG---ECRQSEDYESFSCVCPTGW 861
Query: 2442 GYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSP 2499
T DI+EC + P C +G C NT G +RC C+ GY SG +C D+D+C P
Sbjct: 862 QGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCR--P 913
Query: 2500 KPCNYICKNTEG--SYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTC 2556
PC+ T+G + C C G+ G C+ D++EC + C + + +TC
Sbjct: 914 NPCHNGGSCTDGINTAFCDCLPGF----RGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 2557 KCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DV 2615
CP GF+ H +NN S C G C + SF+C C GF TG C+ DV
Sbjct: 970 TCPAGFSGIHC---ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF----TGSYCQHDV 1022
Query: 2616 DECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWN--QCVDENECSNPNACGSASCYN 2671
+ECD + C HG CQ+ G YRC CPQGY N D + C N C+
Sbjct: 1023 NECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKN-----GGKCWQ 1076
Query: 2672 TLGSYKCACPSGFS------------------------FDQFSSACHD------------ 2695
T Y+C CPSG++ Q C D
Sbjct: 1077 THTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1136
Query: 2696 ---------VNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYRVGQG----HCVSGMGFN 2740
V+ECS S PC G C++ GGY C C GY+ V C+S N
Sbjct: 1137 YTGSYCEDLVDECSPS--PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQN 1194
Query: 2741 KGQYLSL 2747
G L L
Sbjct: 1195 GGTCLDL 1201
Score = 405 bits (1042), Expect = e-112
Identities = 433/1582 (27%), Positives = 602/1582 (38%), Gaps = 364/1582 (23%)
Query: 153 CMNGGTC----ADDHCQCQKGYIGTYCGQP--VCENGCQNGGRC-------IGPNRCACV 199
C+NGG C + C C ++G C P C+N G C + C+C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 200 YGFTGPQC----ERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMC- 254
GF+GP C + T PC G + T+ C G + G C+
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRN-------GGTCDLLTLTEYKCRCPPGWS-GKSCQQAD 142
Query: 255 PAQPQPCRRG---------FI----PNIRTGAC-QDVDECQAIPGICQ-GGNCINTVGSF 299
P PC G +I P+ C QDV+EC PG+C+ GG C N VGS+
Sbjct: 143 PCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSY 202
Query: 300 ECRCPAGHKQSETTQKCE-DIDECSIIPGICETGECSNTVG--SYFCVCPRGY------- 349
C C A H T CE CS P C+ G G ++ C C G+
Sbjct: 203 RCVCRATH----TGPNCERPYVPCS--PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
Query: 350 -VTSTDGSRCIDQRTGMCFSGL--VNGRCAQELPGRMTKM---QCCCEPGRCWGIGTIPE 403
+ G+ C + G C G+ N RC E G+ +C P C GT
Sbjct: 257 NIDDCPGNNC--KNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHN 314
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIP------GSAGSRPGGTGGNGFA------PSGNGNGY 451
Y +C++G SA G T + A P G
Sbjct: 315 T-----HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLL 369
Query: 452 GPGGTGFIPIP---GGNGFSPGVGGAGV---GAGGQGPIITGLTILNQTIDICKHHANLC 505
I P G N + V G + +G GP +Q +D C AN C
Sbjct: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP------ACSQDVDECSLGANPC 423
Query: 506 LN-GRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCTN-GDCVNTPGSYYCKCHA 562
+ G+CI T+ S+ C+C GY C IDV+EC SNPC N C++ G + C C
Sbjct: 424 EHAGKCINTLGSFECQCLQGY---TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
Query: 563 GFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDEC 621
G++ + ++ DEC + L NGRC++ FQC C GF G C D DEC
Sbjct: 481 GYEGVHCE---VNTDECASSPCL-HNGRCLDKINEFQCECPTGF----TGHLCQYDVDEC 532
Query: 622 TTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGS 679
+T C NG C++ ++ C+C G+ G +C D+DEC P C G C + +
Sbjct: 533 AST-PCKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECD-PDPCHYGSCKDGVAT 586
Query: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGE 739
F C C PG G C +T++ +EC +
Sbjct: 587 FTCLCRPGYT----GHHC-ETNI-----------------------NECS--------SQ 610
Query: 740 PCQPCPAKNSAEFHGLCSSGVGITVDGRDIN--ECALDPDICANGICENLRGSYRCNCNS 797
PC+ + LC G T +IN +CA P C +G C + Y C C
Sbjct: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEP 668
Query: 798 GYEPDASGRNC-IDIDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETC-EDIN 854
GY +G C I+IDEC N C N G C + ++C CP GY TC ++N
Sbjct: 669 GY----TGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGY----HDPTCLSEVN 718
Query: 855 ECESNPCVNGACRNNLGSFNCECSPG--------------SKLSSTGLICIDSLKG---T 897
EC SNPCV+GACR++L + C+C PG S G C D G T
Sbjct: 719 ECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 898 CWLNIQDSRCEVNING----------------ATLKSEC---------------CATLGA 926
C C+ NIN A K C CA
Sbjct: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
Query: 927 AWGSPCERCE----LDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHC 980
G C + E CP G +G TCE D+NEC + P C +G C N+ G + C
Sbjct: 839 RNGGECRQSEDYESFSCVCPTGW---QGQTCEVDINECVLSP--CRHGASCQNTHGGYRC 893
Query: 981 ECPEGLTLDGTGRVCL----DIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTE 1036
C G +GR C D R C+ + C + F C C G GT
Sbjct: 894 HCQAGY----SGRNCETDIDDCRPNPCH---NGGSCTDGINTAF----CDCLPGFR-GTF 941
Query: 1037 CEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG-KCRNTIGS 1095
CEE DINEC + P C G C + + S
Sbjct: 942 CEE---------------------------------DINECASDP--CRNGANCTDCVDS 966
Query: 1096 FKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKN 1155
+ C C +GF+ E N D E G CV+ SF C C G+ +
Sbjct: 967 YTCTCPAGFSGIHCENNTPDCTE----SSCFNGGTCVDGINSFTCLCPPGFTGSYCQ--- 1019
Query: 1156 CMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-G 1214
D++EC+ P L GGTC + GS++C CP G+ P+ ++ V + C S C+N G
Sbjct: 1020 -HDVNECDSQPCL-HGGTCQDGCGSYRCTCPQGY-TGPNCQNLV--HWCDSSP--CKNGG 1072
Query: 1215 KCVNMIGTYQCSCNPGY------------QATPDRQGCTDIDECMIMNGGCDTQCTNSEG 1262
KC Y+C C G+ + RQG C +GG C ++
Sbjct: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC--QHGGL---CVDAGN 1127
Query: 1263 SYECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK 1321
++ C C GY G C D +DEC +P +G CT+ G Y C C G+ +
Sbjct: 1128 THHCRCQAGYT----GSYCEDLVDECSPSP-CQNGATCTDYLGGYSCKCVAGYHG---VN 1179
Query: 1322 TCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE------IGA 1375
+++EC L+ G C + ++ C C G +G +VD+C +
Sbjct: 1180 CSEEIDEC-LSHPCQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRS 1235
Query: 1376 HNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCA 1435
C + +C++ G + C+C G++G + D++EC + CV + C
Sbjct: 1236 PKCFNNGTCVDQVGGYSCTCPPGFVGERCEG-DVNECLSNPCDARGTQNCVQRVNDFHCE 1294
Query: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQC---------LNVPGAYRCECEMGFTPASDS 1486
C G TG C IN C+ C N + C+C GF +
Sbjct: 1295 CRAGHTG--------RRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF----EG 1342
Query: 1487 RSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC--TDIDECADPINCV 1543
+C+ D C GTC + P C+C + TG C C C
Sbjct: 1343 ATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF----TGPECQFPASSPCLGGNPCY 1398
Query: 1544 N-GLCVNTPGR--YECNCPPDF 1562
N G C T Y C CP F
Sbjct: 1399 NQGTCEPTSESPFYRCLCPAKF 1420
Score = 292 bits (748), Expect = 3e-78
Identities = 355/1335 (26%), Positives = 501/1335 (37%), Gaps = 288/1335 (21%)
Query: 89 CGSRFHS-YC-CPGWKT---LPGGNQCIVPICR--NSCGDGFCSRPNMCTCSSGQISSTC 141
C R S YC CP +T + CI C ++C + +CTC SG C
Sbjct: 350 CHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 142 GSKSIQQCSVR---CMNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC- 190
S+ + +CS+ C + G C + CQC +GY G C V E N CQN C
Sbjct: 410 -SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL 468
Query: 191 --IGPNRCACVYGFTGPQCE---RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGR 245
IG +C C+ G+ G CE + + PC ++N C ++ C
Sbjct: 469 DQIGEFQCICMPGYEGVHCEVNTDECASSPC---LHNGRCLDKINEFQCE---------- 515
Query: 246 AWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGG-NCINTVGSFECRC 303
C GF ++ CQ DVDEC + P C+ G C++ ++ C C
Sbjct: 516 ---------------CPTGFTGHL----CQYDVDECASTP--CKNGAKCLDGPNTYTCVC 554
Query: 304 PAGHKQSETTQKCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYV---TSTDGSRCI 359
G+ T CE DIDEC P C G C + V ++ C+C GY T+ + C
Sbjct: 555 TEGY----TGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
Query: 360 DQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMD 419
Q C G G C R C C G T C + + C
Sbjct: 609 SQP---CRHG---GTCQD----RDNAYLCFCLKG------TTGPNCEINLDDCASSPCDS 652
Query: 420 GLPMGGIPG-SAGSRPGGTGG--NGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGV 476
G + I G PG TG N GN GGT G NGF+
Sbjct: 653 GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE---DGINGFT-----CRC 704
Query: 477 GAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDV 536
G P T L+ +N+ ++N C++G C +++ Y+C+C+ G+ N D I+
Sbjct: 705 PEGYHDP--TCLSEVNEC------NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCD-INN 754
Query: 537 DECTSNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTD 595
+EC SNPC N G C + Y C C GF P Q +I+EC N L G C++
Sbjct: 755 NECESNPCVNGGTCKDMTSGYVCTCREGFS-GPNCQT--NINECASNPCL-NQGTCIDDV 810
Query: 596 GSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDG--SFKCICKPGFVLAPN 652
++C C L G C V C + G C + SF C+C G+
Sbjct: 811 AGYKCNC----LLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----Q 862
Query: 653 GRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
G+ C D++EC C N+ G +RC C G GR C
Sbjct: 863 GQTCEVDINECVLSPCRHGASCQNTHGGYRCHC----QAGYSGRNC-------------- 904
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINE 771
T + C NP + G C + F C G T DINE
Sbjct: 905 -----------ETDIDDCRPNPCHNGGS----CTDGINTAFCD-CLPGFRGTFCEEDINE 948
Query: 772 CALDPDICANGI-CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTP 830
CA DP C NG C + SY C C +G+ SG +C + + G C +
Sbjct: 949 CASDP--CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGI 1002
Query: 831 GSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLI 889
S++C CPPG+ T + D+NEC+S PC++ G C++ GS+ C C G TG
Sbjct: 1003 NSFTCLCPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQG----YTGPN 1055
Query: 890 CIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE-RCELDTACPRG---- 944
C +L C S C G W + + RCE CP G
Sbjct: 1056 C-QNLVHWC------------------DSSPCKNGGKCWQTHTQYRCE----CPSGWTGL 1092
Query: 945 LARIKGVTCEDVNE---CEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
+ V+CE + +V G CV++ + HC C G TG C D+
Sbjct: 1093 YCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDL--- 1145
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR 1061
DEC P + A C + +C AG+
Sbjct: 1146 -------VDEC---SPSPCQNGATCTDYLGGYSCKCV-----------------AGY--- 1175
Query: 1062 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRC---NSGFALDMEERNCT-DID 1117
G ++I+EC + P G C + ++KC C G ++ +C +D
Sbjct: 1176 ----HGVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVD 1230
Query: 1118 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG-GTCVN 1176
SP +G CV+ G + C C GF+ + D++EC NP RG CV
Sbjct: 1231 PVSRSPKCFNNGTCVDQVGGYSCTC----PPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
Query: 1177 TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCV---NMIGTYQCSCNPGYQ 1232
F C+C GH + R + V IN C C+N G C N + C C G++
Sbjct: 1287 RVNDFHCECRAGH--TGRRCESV-INGC--KGKPCKNGGTCAVASNTARGFICKCPAGFE 1341
Query: 1233 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY----ALMPDGRSCADIDECE 1288
+NGG C + S C C + P C + C
Sbjct: 1342 GATCENDARTCGSLRCLNGG---TCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCY 1398
Query: 1289 NNPDICDGGQC--TNIPGEYRCLC---YDGFMA-----SMDMKTCIDVNECDLNSNICMF 1338
N G C T+ YRCLC ++G + S D+ L C
Sbjct: 1399 NQ------GTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPP-PLIEEACEL 1451
Query: 1339 GECENTKGSFICHCQ 1353
EC+ G+ +C Q
Sbjct: 1452 PECQEDAGNKVCSLQ 1466
Score = 130 bits (328), Expect = 1e-29
Identities = 116/369 (31%), Positives = 157/369 (42%), Gaps = 63/369 (17%)
Query: 67 GAAVASRVRRRGQQDVL-RGPNVCGSRFHSYCCPGWKTLPGGN--QCIVPICRNSCGDGF 123
G V GQ+ L R C + SY C T G N + VP + C +G
Sbjct: 172 GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGG 231
Query: 124 CSRP-----NMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADD----HCQCQKGYIGT 173
RP + C C G C ++I C C NGG C D +C+C + G
Sbjct: 232 TCRPTGDVTHECACLPGFTGQNC-EENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQ 290
Query: 174 YCGQPVCE-----NGCQNGGRCI---GPNRCACVYGFTGPQCERD---------YRTGPC 216
YC + V E N CQNGG C G C CV G+TG C + + C
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 217 FTQVNNQMCQGQ--LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQP---CRRGFIPNIRT 271
+V + C+ TG++C C + G C+ P + C G+ T
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY-----T 405
Query: 272 G-AC-QDVDECQAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPG 327
G AC QDVDEC C+ G CINT+GSFEC+C G+ T +CE D++EC P
Sbjct: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNECVSNP- 460
Query: 328 ICET-GECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMT 384
C+ C + +G + C+C GY +G C + T C S L NGRC ++
Sbjct: 461 -CQNDATCLDQIGEFQCICMPGY----EGVHC-EVNTDECASSPCLHNGRCLD----KIN 510
Query: 385 KMQCCCEPG 393
+ QC C G
Sbjct: 511 EFQCECPTG 519
Score = 122 bits (306), Expect = 5e-27
Identities = 169/672 (25%), Positives = 231/672 (34%), Gaps = 134/672 (19%)
Query: 97 CCPGWKTL---PGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRC 153
C PG++ N+C CRN C CTC +G C + + C
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
Query: 154 MNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC---IGPNRCACVYGFT 203
NGGTC D C C G+ G+YC V E C +GG C G RC C G+T
Sbjct: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
Query: 204 GPQCERDYR---TGPCFT-----QVNNQM---CQGQLTGIVC-TKTLCCATIGRAWG-HP 250
GP C+ + PC Q + Q C TG+ C ++ C + G
Sbjct: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
Query: 251 CEMCPAQPQPCRRGFIPNIRTGA------CQD-VDECQAIPGICQ-GGNCINTVGSFECR 302
+C G + R A C+D VDEC P CQ G C + +G + C+
Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCK 1170
Query: 303 CPAGHKQSETTQKCEDIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTSTDGSRC--- 358
C AG+ + E+IDEC P C+ G C + +Y C CPRG T G C
Sbjct: 1171 CVAGYHGVNCS---EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRG----TQGVHCEIN 1221
Query: 359 ID---------QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG----RCWG--IGTIPE 403
+D R+ CF+ NG C ++ G C C PG RC G +
Sbjct: 1222 VDDCNPPVDPVSRSPKCFN---NGTCVDQVGG----YSCTCPPGFVGERCEGDVNECLSN 1274
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGG--NGFAPSGNGNGYGPGGTGFIPI 461
C RG++ + D R G TG G GGT +
Sbjct: 1275 PCDARGTQNCVQRVND--------FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVAS 1326
Query: 462 PGGNGF--SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRC 519
GF G G L LN I + CL C+ + C
Sbjct: 1327 NTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCL---CLGPFTGPEC 1383
Query: 520 ECNMGYKQDANGDCIDVDECTSNPCTN-GDCVNTPGS--YYCKCHAGFQ----------- 565
+ A+ C+ NPC N G C T S Y C C A F
Sbjct: 1384 QF------PASSPCLG-----GNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSF 1432
Query: 566 --------RTPTKQACIDIDECIQN------GVLCKNGRCVNTDGSFQCICNAGFELTTD 611
P + ++ EC ++ + C N C G C+ F
Sbjct: 1433 GGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGD----CSLNF--NDP 1486
Query: 612 GKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNG 671
KNC +C +G C ++ S C+ GF C + + +G
Sbjct: 1487 WKNCTQSLQC--WKYFSDGHCDSQCNSAGCLF-DGFDCQRAEGQCNPLYDQYCKDHFSDG 1543
Query: 672 HCINSEGSFRCD 683
HC S C+
Sbjct: 1544 HCDQGCNSAECE 1555
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 472 bits (1215), Expect = e-132
Identities = 288/891 (32%), Positives = 411/891 (46%), Gaps = 128/891 (14%)
Query: 1894 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNT 1951
NEC P++C G C++L Y CIC+ G++ S+ Q C+D+DEC + H C G C+NT
Sbjct: 876 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 935
Query: 1952 VGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGRCFNEIGSFKC-LCNEGYELTP 2009
GS+ C+C GF + +C+D+DEC VC G C N +G+F+C C+ GY +T
Sbjct: 936 EGSFLCICPAGFMASEEGTNCIDVDECLR--PDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 993
Query: 2010 DGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI-CPPGYEVKSENCIDINECDEDPNICL 2068
G+ C D +EC+ P +C C N GS++C+ C G+ + C+D++EC E PN+C
Sbjct: 994 RGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCA 1050
Query: 2069 FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2128
G C+N G + C C G+ + + + C D + NG+C
Sbjct: 1051 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQC--------------- 1095
Query: 2129 SKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCI 2188
K+ E +F+ C G+ + + D ED++EC + +C++GQC
Sbjct: 1096 ----------------KNTEGSFRCTCGQGY-QLSAAKDQCEDIDEC-QHRHLCAHGQCR 1137
Query: 2189 NTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFECNCNEGFEPGP 2247
NT+GSF+C C GY G C D +EC + C G C N GS++C C +GF+
Sbjct: 1138 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD 1197
Query: 2248 MMNCEDINECAQNPLLCAFR--CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
C+DINEC ++P LC + C+NT GS+ C C G+++ D + C+D+DEC C
Sbjct: 1198 NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV-C 1255
Query: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2365
+S G C N G+F C+C G DG+GCVD NEC G+C C N+ GS+ C C
Sbjct: 1256 DSHGF-CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 1314
Query: 2366 NEGFQSSSSGT-ECLDNRQGLCFAEVLQTICQMASSSRNL-------------VTKSECC 2411
+ Q S T +C +V Q + NL VTK ECC
Sbjct: 1315 ADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC 1374
Query: 2412 CDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG-----------RDIDECKVM-P 2457
C G GWG CE+ CP+ GTA++ ++CP G G+ G +D DEC +
Sbjct: 1375 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1434
Query: 2458 NLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCS 2516
+C NG C+NT + C+CK G D C D+DEC Q P C + C NTEGSY C
Sbjct: 1435 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCF 1493
Query: 2517 CPRGYVLQEDGKTC-------KDLDECQTKQHNC------QFLCVNTLGGFTCKCPPGFT 2563
C VL K C + ++E Q C +++C L G T
Sbjct: 1494 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT------T 1547
Query: 2564 QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR 2623
C+ G Q +LC K S + + ++ TG R
Sbjct: 1548 YTECCCLYGEAWGMQCALCPLKD---------SDDYAQLCNIPVTG------------RR 1586
Query: 2624 CQHGCQNILGGYRCGCPQG---YIQHYQWNQC--VDENECSNPNACGSASCYNTLGSYKC 2678
+G ++ P+ +IQ N + EC N C + C Y C
Sbjct: 1587 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC 1646
Query: 2679 ACPSGFSFDQFSSACHDVNECSSSKNPC----NYGCSNTEGGYLCGCPPGY 2725
C G+ D C DVNEC N N C NT+G Y C C PGY
Sbjct: 1647 DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1697
Score = 467 bits (1202), Expect = e-131
Identities = 283/864 (32%), Positives = 409/864 (47%), Gaps = 144/864 (16%)
Query: 1158 DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCV 1217
+I+EC NP +C G C+N + C C G+ S + CVDI+EC+ +LC G+C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 1218 NMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS-CSEGYALMP 1276
N G++ C C G+ A+ + C D+DEC+ + + C N+ G++ C C GY +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 993
Query: 1277 DGRSCADIDECENNPDICDGGQCTNIPGEYRCL-CYDGFMASMDMKTCIDVNECDLNSNI 1335
GR C DIDEC NP C QC N PG Y+C+ C +GF C+DV+EC L N+
Sbjct: 994 RGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDEC-LEPNV 1048
Query: 1336 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
C G+C N +GS++C C GY+ C D+DEC+ G N ++ C N GSF+C+C
Sbjct: 1049 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG--NLCVNGQCKNTEGSFRCTC 1106
Query: 1396 REGWIGNGIK--CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSDVD 1451
+G+ + K C D+DEC + H C+ + QC NT GS++C C +G+ +G G C D++
Sbjct: 1107 GQGYQLSAAKDQCEDIDECQH-RHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCEDIN 1164
Query: 1452 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLP 1510
EC E+ ++C+ G C+N G+Y C C GF D+++CQDI+EC +C G C N
Sbjct: 1165 ECLEDKSVCQRGDCINTAGSYDCTCPDGF-QLDDNKTCQDINECEHPGLCGPQGECLNTE 1223
Query: 1511 GMFHCICDDGYELDRTGGNCTDIDECADPINC-VNGLCVNTPGRYECNCPPDFQLNPTGV 1569
G FHC+C G+ + G C DIDEC + C +G C NT G + C C FQ G
Sbjct: 1224 GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 1283
Query: 1570 GCVDNRVGNCYLKFGPRG-------DGSLSC--------------------NTEIGV--- 1599
GCVD V C L G G +GS C +T++ V
Sbjct: 1284 GCVD--VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1341
Query: 1600 -------------------------GVSRSSCCCSLGKAWGNPCE--TCPPVNSTEYYTL 1632
V++ CCC+ G WG+ CE CP + + E+ +
Sbjct: 1342 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1401
Query: 1633 CPGGEGFRPNPITII------LEDIDEC----QELPGLCQGGNCINTFGSFQCECPQGYY 1682
CP G+GF P + +D DEC QE +C+ G C+NT ++C C QG Y
Sbjct: 1402 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQE---ICKNGFCLNTRPGYECYCKQGTY 1458
Query: 1683 LSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM--------- 1733
C D+DEC P C G C NT G+Y C C + C+
Sbjct: 1459 YDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1517
Query: 1734 ---DMRKSFCYRSYNGT-TCENEL-PFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFK 1788
D+ + C+ + C L T CCC Y G+AW C CP + D+
Sbjct: 1518 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYA 1575
Query: 1789 TICGNI--------------------------PGFTFD--IHTGKAVDIDECKEIPGICA 1820
+C NI P F D +++ + + +EC + G C
Sbjct: 1576 QLC-NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1633
Query: 1821 NGVCINQIGSFRCECPTGFSYNDLLLVCEDIDEC---SNGDNLCQRNADCINSPGSYRCE 1877
NG C+ + C+C G+ + + C D++EC +N +LC +NA CIN+ GSY+C
Sbjct: 1634 NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLC-KNAKCINTDGSYKCL 1692
Query: 1878 CAAGFKLS--PNGACVDRNECLEI 1899
C G+ S PN C N L +
Sbjct: 1693 CLPGYVPSDKPN-YCTPLNTALNL 1715
Score = 456 bits (1172), Expect = e-127
Identities = 294/856 (34%), Positives = 394/856 (46%), Gaps = 99/856 (11%)
Query: 1283 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1342
+I+EC NPDIC G C N+P Y C+CY+G+ S + C+D++EC ++C G CE
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 1343 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-CREGW-I 1400
NT+GSF+C C G+ + T C DVDEC + C C+N G+F+C C G+ +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCG-EGHCVNTVGAFRCEYCDSGYRM 991
Query: 1401 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCA-CSEGFTGDGFTCSDVDECAENINL 1459
+C D+DEC N + C + QCVN+PGSY+C C+EGF G C DVDEC E N+
Sbjct: 992 TQRGRCEDIDECLNPS-TCP-DEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-NV 1048
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
C NG C N+ G+Y C C G+T D + C+DIDEC N+CV G C N G F C C
Sbjct: 1049 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQ 1108
Query: 1520 GYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC 1579
GY+L C DIDEC C +G C NT G ++C C ++ + G C D + C
Sbjct: 1109 GYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INEC 1166
Query: 1580 Y--LKFGPRGD-----GSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE---TCPPVN---S 1626
RGD GS C G + + C + N CE C P +
Sbjct: 1167 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI-----NECEHPGLCGPQGECLN 1221
Query: 1627 TEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSED 1686
TE C +GF + EDIDEC G C NT GSF+C C QG+ +D
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQD 1281
Query: 1687 TRICEDIDECFAHPGVCGPGTCYNTLGNYTCICP---PEYMQVNG---GHNCMDM----- 1735
+ C D++EC GVCG C N G++ C+C EY + G D+
Sbjct: 1282 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1341
Query: 1736 ----RKSFCYRSYN-GTTCENELPFNVTKRMCCCTYNVGKAWNKPCE--PCPTPGTADFK 1788
K CY + N + C+N L NVTK+ CCCT G W CE PCP GTA+F
Sbjct: 1342 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG--WGDNCEIFPCPVLGTAEFT 1399
Query: 1789 TIC----GNIPGFTFDIHTG--KAVDIDECKEI-PGICANGVCINQIGSFRCECPTGFSY 1841
+C G +P G D DEC IC NG C+N + C C G Y
Sbjct: 1400 EMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYY 1459
Query: 1842 NDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL-SPNGACV---DRNECL 1897
+ + L C D+DEC + + + C+N+ GSY C C L + C+ + NE +
Sbjct: 1460 DPVKLQCFDMDECQDPSSCI--DGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1517
Query: 1898 EIPN--------------VCSHGLCVDLQGSY-QCICHNGFKASQDQTMC--MDVDEC-- 1938
E + VCS L V Q +Y +C C G +C D D+
Sbjct: 1518 EETDVYQDLCWEHLSDEYVCSRPL-VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1576
Query: 1939 --------ERHPCGNGTCKNTVGSYNCLCYPGF---ELTHNNDCLDIDECSSFFGQVCRN 1987
R P G + Y P F ++ + L +EC G C N
Sbjct: 1577 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG--CEN 1634
Query: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGS---CSPGTCQNLEGSFRCICP 2044
GRC + C C +GY L C+D NEC L C C N +GS++C+C
Sbjct: 1635 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1694
Query: 2045 PGY--EVKSENCIDIN 2058
PGY K C +N
Sbjct: 1695 PGYVPSDKPNYCTPLN 1710
Score = 416 bits (1069), Expect = e-115
Identities = 279/877 (31%), Positives = 392/877 (44%), Gaps = 124/877 (14%)
Query: 535 DVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCV 592
+++ECT NP C G C+N P Y C C+ G++ + ++ C+DIDEC Q LC GRC
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 593 NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKC-ICKPGFVLAP 651
NT+GSF CIC AGF + +G NC+D DEC ++C G C+N G+F+C C G+ +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 993
Query: 652 NGRYCTDVDECQTPGICMNGHCINSEGSFRC-DCPPGLAVGMDGRVCVDTHMRSTCYGGI 710
GR C D+DEC P C + C+NS GS++C C G G +G+ C+D C +
Sbjct: 994 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDV---DEC---L 1044
Query: 711 KKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG---- 766
+ VC + S C + Y + C + + LC +G +G
Sbjct: 1045 EPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC 1104
Query: 767 ---------------RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
DI+EC +CA+G C N GS++C C+ GY G +C DI
Sbjct: 1105 TCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 1163
Query: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCV---NGACRN 868
+ECL ++ +C G C NT GSY CTCP G+ + +TC+DINECE +P + G C N
Sbjct: 1164 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECE-HPGLCGPQGECLN 1221
Query: 869 NLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAW 928
GSF+C C G +S+ G C D C VN C T G+
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTCEDI-----------DEC-VNNTVCDSHGFCDNTAGSF- 1268
Query: 929 GSPCERCELDTACPRGL-ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPE--- 984
RC C +G A G C DVNECE+ GVC C N +GSF C C +
Sbjct: 1269 -----RC----LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQ 1319
Query: 985 ---GLTLDGTGRVCLDIRME---------QCYLKW-DEDECIHPVPGKFRMDACCCAVGA 1031
+T R D+ ++ +CY D C + + CCC GA
Sbjct: 1320 EYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGA 1379
Query: 1032 AWGTECE--ECPKPGTKEYETLCPRGAGFANRGDVLT--GRPFYKDINECKAF-PGMCTY 1086
WG CE CP GT E+ +CP+G GF G+ + G YKD +EC F +C
Sbjct: 1380 GWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1439
Query: 1087 GKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
G C NT ++C C G D + C D+DEC+ P C G CVNT GS+ C C
Sbjct: 1440 GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPM 1498
Query: 1147 ESGFMMMKNCM-------DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCV 1199
K C+ I+E + LC + + C PL + + E C
Sbjct: 1499 VLD-ASEKRCIRPAESNEQIEETDVYQDLC----WEHLSDEYVCSRPLVGKQTTYTECCC 1553
Query: 1200 DINE--------CSLSDN-----LCR-----------NGKCVNMIGTYQCSCNPGYQATP 1235
E C L D+ LC V+ Y +P +
Sbjct: 1554 LYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDR 1613
Query: 1236 DRQGCTDI--DECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECE---NN 1290
++ +EC I+NG + +C + Y C C +GY L +C D++EC+ N
Sbjct: 1614 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1673
Query: 1291 PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
+C +C N G Y+CLC G++ S C +N
Sbjct: 1674 MSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 414 bits (1064), Expect = e-115
Identities = 299/942 (31%), Positives = 406/942 (43%), Gaps = 170/942 (18%)
Query: 852 DINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI-QDSRCE 908
+INEC NP C G C N + C C G + S C+D + T ++ RCE
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 909 VNINGATLKSECCATLGAAWGSPCERCELDTACPRG-LARIKGVTCEDVNECEVFPGVCP 967
N G+ L CP G +A +G C DV+EC + P VC
Sbjct: 934 -NTEGSFL----------------------CICPAGFMASEEGTNCIDVDEC-LRPDVCG 969
Query: 968 NGRCVNSKGSFHCE-CPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACC 1026
G CVN+ G+F CE C G + GR C DI DEC++P D C
Sbjct: 970 EGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDI-----------DECLNPSTCP---DEQC 1014
Query: 1027 CAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY 1086
V + +C C + G + + C D++EC P +C
Sbjct: 1015 --VNSPGSYQCVPCTE-GFRGWNGQC-------------------LDVDECLE-PNVCAN 1051
Query: 1087 GKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
G C N GS+ C C+ G+ + ++C DIDEC+ +LC +G C NT GSF C C +GY
Sbjct: 1052 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGY 1110
Query: 1147 ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSL 1206
+ C DIDEC+ L C G C NTEGSFQC C G+ S + C DINEC
Sbjct: 1111 QLS-AAKDQCEDIDECQHRHL-CAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLE 1168
Query: 1207 SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ--CTNSEGSY 1264
++C+ G C+N G+Y C+C G+Q D + C DI+EC G C Q C N+EGS+
Sbjct: 1169 DKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECE-HPGLCGPQGECLNTEGSF 1226
Query: 1265 ECSCSEGYALMPDGRSCADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMKTC 1323
C C +G+++ DGR+C DIDEC NN +CD G C N G +RCLCY GF A D + C
Sbjct: 1227 HCVCQQGFSISADGRTCEDIDECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 1285
Query: 1324 IDVNECDLNSNICMFGECENTKGSFICHC---QLGYSVKKG-----TTGCTDVD------ 1369
+DVNEC+L S +C CEN +GSF+C C YS G T+ DVD
Sbjct: 1286 VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKE 1345
Query: 1370 ECEIGAHNCDMHASCLNI--PGSFK--CSCREGWIGNGIKCIDLDECSNGTHQCSINAQC 1425
E + +N + + C N+ P K C C G G G C GT C
Sbjct: 1346 EKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPCPVLGT--AEFTEMC 1402
Query: 1426 VNTPGSYRCACSEGFTGDGFTCSDVDEC-AENINLCENGQCLNVPGAYRCECEMGFTPAS 1484
G S G G D DEC +C+NG CLN Y C C+ G
Sbjct: 1403 PKGKGFVPAGESSSEAG-GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1461
Query: 1485 DSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC---TDIDECADPIN 1541
C D+DEC + C+ G C N G ++C C LD + C + +E + +
Sbjct: 1462 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETD 1521
Query: 1542 CVNGLC-VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVG 1600
LC + Y C+ P +G
Sbjct: 1522 VYQDLCWEHLSDEYVCSRP------------------------------------LVGKQ 1545
Query: 1601 VSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLC---------PGG--------EGFRPNP 1643
+ + CCC G+AWG C CP +S +Y LC P G E + P
Sbjct: 1546 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEA 1605
Query: 1644 ITIILED----------IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI 1693
++D +EC L G C+ G C+ + C+C GY+L C D+
Sbjct: 1606 DPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1664
Query: 1694 DECFA---HPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC 1732
+EC +C C NT G+Y C+C P Y+ + + C
Sbjct: 1665 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1706
Score = 414 bits (1064), Expect = e-115
Identities = 283/852 (33%), Positives = 384/852 (45%), Gaps = 158/852 (18%)
Query: 1796 GFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS 1855
G+ F K VDIDEC ++ +C+ G C N GSF C CP GF ++ C D+DEC
Sbjct: 904 GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECL 963
Query: 1856 NGDNLCQRNADCINSPGSYRCE-CAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGS 1914
D +C C+N+ G++RCE C +G++++ G C D +ECL P+ C CV+ GS
Sbjct: 964 RPD-VCGEG-HCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGS 1020
Query: 1915 YQCI-CHNGFKASQDQTMCMDVDEC-ERHPCGNGTCKNTVGSYNCLCYPGFELTHNND-C 1971
YQC+ C GF+ Q C+DVDEC E + C NG C N GSY C C+ G+ T ++ C
Sbjct: 1021 YQCVPCTEGFRGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHC 1078
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 2031
DIDEC G +C NG+C N GSF+C C +GY+L+ C D +EC C+ G
Sbjct: 1079 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQ 1135
Query: 2032 CQNLEGSFRCICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVL 2089
C+N EGSF+C+C GY ++C DINEC ED ++C G C NT G + C CP GF L
Sbjct: 1136 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 1195
Query: 2090 SDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEV 2149
DN + C D + C P G P C + E
Sbjct: 1196 DDN-KTCQDINE-----------CEHP------------------GLCGPQGEC-LNTEG 1224
Query: 2150 AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGV 2209
+F +C G ++ + T ED++EC+ + S+G C NT GSFRC C G+ G
Sbjct: 1225 SFHCVCQQGF-SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 1283
Query: 2210 RCVDTDECSI-GNPCGNGTCTNVIGSFECNC-NEGFEPGPMMN-C--------------- 2251
CVD +EC + CG C NV GSF C C +E E PM C
Sbjct: 1284 GCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1343
Query: 2252 -EDINECAQNPLLCAFRCMNTFG----SYECTCPIG--------------YALREDQKMC 2292
E+ EC N L A C N EC C G E +MC
Sbjct: 1344 KEEKKECYYN-LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMC 1402
Query: 2293 ---------------------KDLDECAE-GLHDCESRGMMCKNLIGTFMCICPPGMARR 2330
KD DEC G C++ C N + C C G
Sbjct: 1403 PKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG--FCLNTRPGYECYCKQGTYYD 1460
Query: 2331 PDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL---DNRQGLCF 2387
P C D +EC+ P C +G+CVN GSY C C +S C+ ++ + +
Sbjct: 1461 PVKLQCFDMDECQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1519
Query: 2388 AEVLQTICQMASS-----SRNLVTK----SECCCDGGRGWGHQCELCPLPGTAQYKKIC- 2437
+V Q +C S SR LV K +ECCC G WG QC LCPL + Y ++C
Sbjct: 1520 TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN 1579
Query: 2438 --------PHGPGYTTDGRD-----------------------IDECKVMPNLCTNGQCI 2466
P+G D + +EC ++ N C NG+C+
Sbjct: 1580 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCV 1638
Query: 2467 NTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC----NYICKNTEGSYQCSCPRGYV 2522
+ C C GY D + +C+D++EC + N C NT+GSY+C C GYV
Sbjct: 1639 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1698
Query: 2523 LQEDGKTCKDLD 2534
+ C L+
Sbjct: 1699 PSDKPNYCTPLN 1710
Score = 392 bits (1006), Expect = e-108
Identities = 278/918 (30%), Positives = 388/918 (42%), Gaps = 190/918 (20%)
Query: 1448 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTC 1506
++++EC N ++C G C+N+P Y C C G+ + R C DIDEC+ Q++C G C
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 1507 NNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLN 1565
N G F CIC G+ G NC D+DEC P C G CVNT G + C C +++
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
G C D + C ++ S+C P E C VN
Sbjct: 993 QRG-RCED--IDEC---------------------LNPSTC----------PDEQC--VN 1016
Query: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
S Y P EGFR + D+DEC E P +C G+C N GS+ C C +GY +
Sbjct: 1017 SPGSYQCVPCTEGFRGWNGQCL--DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTP 1073
Query: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
D + C DIDEC +C G C NT G++ C C Y C D+ +
Sbjct: 1074 DHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE-------- 1124
Query: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1805
C++ + +C G+ N T G+ F+ +C G+
Sbjct: 1125 ---CQH-------RHLCAH----GQCRN-------TEGS--FQCVCDQ--GYRASGLGDH 1159
Query: 1806 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA 1865
DI+EC E +C G CIN GS+ C CP GF +D C+DI+EC + LC
Sbjct: 1160 CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEH-PGLCGPQG 1217
Query: 1866 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
+C+N+ GS+ C C GF +S +G C D +EC+ SHG C + GS++C+C+ GF+
Sbjct: 1218 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 1277
Query: 1925 ASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLC---------YPGFELTHNNDCLD 1973
A QD C+DV+ECE CG C+N GS+ C+C G + + LD
Sbjct: 1278 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1337
Query: 1974 ID---------ECSSFFGQ--VCRNGRCFNEIGSFKCLCNEGY----------------- 2005
+D EC +C N N + +C C G
Sbjct: 1338 VDVDQPKEEKKECYYNLNDASLCDNVLAPN-VTKQECCCTSGAGWGDNCEIFPCPVLGTA 1396
Query: 2006 ---ELTPDGKNCI---------------DTNECVALPGS-CSPGTCQNLEGSFRCICPPG 2046
E+ P GK + D +EC+ C G C N + C C G
Sbjct: 1397 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1456
Query: 2047 --YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCF------- 2097
Y+ C D++EC +DP+ C+ G C NT G + C C VL + +RC
Sbjct: 1457 TYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNE 1515
Query: 2098 -----DTRQSFCFTNFENGK-CSVPKAFN-TTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
D Q C+ + + CS P TT +CCC + GE WG C LCP D
Sbjct: 1516 QIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC--LYGEAWGMQCALCPLKDSDD 1573
Query: 2151 FQDLC---------PYGHGTVPSLHD--TRE-----------------DVNECLESPGIC 2182
+ LC PYG + + T E EC G C
Sbjct: 1574 YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-C 1632
Query: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP----CGNGTCTNVIGSFECN 2238
NG+C+ + C+C GY+LD + CVD +EC N C N C N GS++C
Sbjct: 1633 ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1692
Query: 2239 CNEGFEPGPMMN-CEDIN 2255
C G+ P N C +N
Sbjct: 1693 CLPGYVPSDKPNYCTPLN 1710
Score = 371 bits (952), Expect = e-102
Identities = 261/851 (30%), Positives = 363/851 (42%), Gaps = 183/851 (21%)
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCT 2073
+ NEC P C G C NL + CIC GY + C+DI+EC + ++C G C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 2074 NTPGGFQCLCPPGFVLSDNGRRCFDT---------------------RQSFCFTNF---E 2109
NT G F C+CP GF+ S+ G C D R +C + + +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 993
Query: 2110 NGKC-SVPKAFN-TTKAKCCCSKMPG-----------EGWGDPC---------ELCPKDD 2147
G+C + + N +T C PG GW C +C D
Sbjct: 994 RGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 1053
Query: 2148 ----EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYN 2203
E ++ C G+ P H D++EC + +C NGQC NT+GSFRC C GY
Sbjct: 1054 CSNLEGSYMCSCHKGYTRTPD-HKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQ 1111
Query: 2204 LDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPL 2262
L +C D DEC + C +G C N GSF+C C++G+ G +CEDINEC ++
Sbjct: 1112 LSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS 1171
Query: 2263 LC-AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFM 2320
+C C+NT GSY+CTCP G+ L +D K C+D++EC GL C +G C N G+F
Sbjct: 1172 VCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL--CGPQG-ECLNTEGSFH 1227
Query: 2321 CICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLD 2380
C+C G + DG C D +EC +G C N GS+RC C +GFQ+ G C+D
Sbjct: 1228 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 1287
Query: 2381 NRQ-----GLC---FAEVLQ----TICQMASSSRNLVT---------------------K 2407
+ G+C F E ++ +C + + +T K
Sbjct: 1288 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1347
Query: 2408 SEC-----------------------CCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPG 2442
EC CC G GWG CE+ CP+ GTA++ ++CP G G
Sbjct: 1348 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1407
Query: 2443 YTTDG-----------RDIDECKVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2490
+ G +D DEC + +C NG C+NT + C+CK G D C
Sbjct: 1408 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1467
Query: 2491 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTC-------KDLDECQTKQHN 2542
D+DEC Q P C + C NTEGSY C C VL K C + ++E Q
Sbjct: 1468 DMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDL 1526
Query: 2543 C------QFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKG------ICQN 2590
C +++C L G T C+ G Q +LC K +C N
Sbjct: 1527 CWEHLSDEYVCSRPLVG------KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-N 1579
Query: 2591 TP-----------------GSFSCECQRGFSLDATGLNCEDV--DECDGNHRCQHG-CQN 2630
P ++ E F D + E++ +EC + C++G C
Sbjct: 1580 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVR 1639
Query: 2631 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPN----ACGSASCYNTLGSYKCACPSGFSF 2686
+ GY C C GY CVD NEC N C +A C NT GSYKC C G+
Sbjct: 1640 VQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVP 1699
Query: 2687 DQFSSACHDVN 2697
+ C +N
Sbjct: 1700 SDKPNYCTPLN 1710
Score = 364 bits (935), Expect = e-100
Identities = 253/793 (31%), Positives = 350/793 (44%), Gaps = 153/793 (19%)
Query: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDEC-TSNPCTNGDCVNT 552
ID C +LC GRC T S+ C C G+ G +CIDVDEC + C G CVNT
Sbjct: 917 IDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNT 976
Query: 553 PGSYYCK-CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCI-CNAGFELTT 610
G++ C+ C +G++ T + C DIDEC+ N C + +CVN+ GS+QC+ C GF
Sbjct: 977 VGAFRCEYCDSGYRMT-QRGRCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR--- 1031
Query: 611 DGKN--CVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGIC 668
G N C+D DEC N+C NG C N +GS+ C C G+ P+ ++C D+DECQ +C
Sbjct: 1032 -GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC 1090
Query: 669 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVD----THMRSTCYG------GIKKGVCVRP 718
+NG C N+EGSFRC C G + C D H +G G + VC +
Sbjct: 1091 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG 1150
Query: 719 FPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG----RDINECAL 774
+ + C N CQ N+A + C+ G +D +DINEC
Sbjct: 1151 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECE- 1208
Query: 775 DPDICA-NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD-NGLCRNTPGS 832
P +C G C N GS+ C C G+ A GR C DIDEC VN +CD +G C NT GS
Sbjct: 1209 HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGS 1267
Query: 833 YSCTCPPGYVFRTETETCEDINECE--SNPCVNGACRNNLGSFNCECSPGSK-------- 882
+ C C G+ + + C D+NECE S C C N GSF C C+ ++
Sbjct: 1268 FRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQ 1327
Query: 883 ---LSSTGL-ICID---SLKGTCWLNIQD-SRCEVNINGATLKSECCATLGAAWGSPCE- 933
+ST L + +D K C+ N+ D S C+ + K ECC T GA WG CE
Sbjct: 1328 CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEI 1387
Query: 934 -------RCELDTACPRGLARIK---------GVTCEDVNECEVF--------------- 962
E CP+G + G +D +EC +F
Sbjct: 1388 FPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRP 1447
Query: 963 ---------------------------PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
P C +G+CVN++GS++C C + LD + + C
Sbjct: 1448 GYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1507
Query: 996 L------------DIRMEQCYLKW-DEDECIHPVPGK-FRMDACCCAVGAAWGTECEECP 1041
+ D+ + C+ DE C P+ GK CCC G AWG +C CP
Sbjct: 1508 IRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCP 1567
Query: 1042 KPGTKEYETLC---------PRG----AGFANRGDVLTGRPFYKD----------INECK 1078
+ +Y LC P G F+ + F +D EC
Sbjct: 1568 LKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG 1627
Query: 1079 AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDEC-----RISPDLCGSGICVN 1133
G C G+C + C C G+ LD + C D++EC R+S LC + C+N
Sbjct: 1628 ILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS--LCKNAKCIN 1684
Query: 1134 TPGSFECECFEGY 1146
T GS++C C GY
Sbjct: 1685 TDGSYKCLCLPGY 1697
Score = 363 bits (933), Expect = 1e-99
Identities = 252/812 (31%), Positives = 364/812 (44%), Gaps = 113/812 (13%)
Query: 503 NLCLNGRCIPTVSSYRCE-CNMGYKQDANGDCIDVDECTS-NPCTNGDCVNTPGSYYC-K 559
++C G C+ TV ++RCE C+ GY+ G C D+DEC + + C + CVN+PGSY C
Sbjct: 966 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP 1025
Query: 560 CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHD 619
C GF+ + C+D+DEC++ V C NG C N +GS+ C C+ G+ T D K+C D D
Sbjct: 1026 CTEGFRGWNGQ--CLDVDECLEPNV-CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 1082
Query: 620 ECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGS 679
EC N+C+NG C N +GSF+C C G+ L+ C D+DECQ +C +G C N+EGS
Sbjct: 1083 ECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGS 1142
Query: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGE 739
F+C C G G C D + ++G C+ T C PD GF
Sbjct: 1143 FQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN------TAGSYDCTCPD-GF-- 1193
Query: 740 PCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSG 798
+ + C +DINEC P +C G C N GS+ C C G
Sbjct: 1194 ---------QLDDNKTC----------QDINECE-HPGLCGPQGECLNTEGSFHCVCQQG 1233
Query: 799 YEPDASGRNCIDIDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECE 857
+ A GR C DIDEC VN +CD+ G C NT GS+ C C G+ + + C D+NECE
Sbjct: 1234 FSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECE 1292
Query: 858 --SNPCVNGACRNNLGSFNCECSPGSK-----------LSSTGL-ICIDSLKGT---CWL 900
S C C N GSF C C+ ++ +ST L + +D K C+
Sbjct: 1293 LLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY 1352
Query: 901 NIQD-SRCEVNINGATLKSECCATLGAAWGSPCE--------RCELDTACPRGLARIK-- 949
N+ D S C+ + K ECC T GA WG CE E CP+G +
Sbjct: 1353 NLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1412
Query: 950 -------GVTCEDVNECEVF-PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
G +D +EC +F +C NG C+N++ + C C +G D C D M+
Sbjct: 1413 ESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFD--MD 1470
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR 1061
+C D CI D C ++ C E + P A
Sbjct: 1471 ECQ---DPSSCI---------DGQCVNTEGSYNCFCTHPMVLDASEKRCIRP-----AES 1513
Query: 1062 GDVLTGRPFYKDIN-ECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCT--DIDE 1118
+ + Y+D+ E + +C+ +C C G A M+ C D D+
Sbjct: 1514 NEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDD 1573
Query: 1119 ----CRISP----DLCGSGICVNTPGSFECECFEGY-ESGFMMMKNCMDIDECERNPLL- 1168
C I G V+ + E + + F+ + +EC +L
Sbjct: 1574 YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG---ILN 1630
Query: 1169 -CRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDN---LCRNGKCVNMIGTYQ 1224
C G CV + + CDC G+ L ++ CVD+NEC +N LC+N KC+N G+Y+
Sbjct: 1631 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1690
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
C C PGY + CT ++ + + D +
Sbjct: 1691 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE 1722
Score = 362 bits (930), Expect = 2e-99
Identities = 249/824 (30%), Positives = 346/824 (41%), Gaps = 134/824 (16%)
Query: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 335
+++EC P IC G+CIN + C C G++ SE +KC DIDEC+ + +C G C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 336 NTVGSYFCVCPRGYVTSTDGSRCIDQRT---------GMCFSGLVNGRCAQELPG-RMTK 385
NT GS+ C+CP G++ S +G+ CID G C + + RC G RMT+
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 993
Query: 386 MQCCCEPGRCWGIGTIPEACPVRGSEEYRRL-CMDGLP--MGGIPGSAGSRPGGTGGNGF 442
C + C T P+ V Y+ + C +G G NG
Sbjct: 994 RGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 1053
Query: 443 APSGNGNGYGPGGTGFIPIPGG----------------NGFSPGVGGAGVGAGGQGPIIT 486
+ G+ G+ P NG G+ GQG ++
Sbjct: 1054 CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLS 1113
Query: 487 GLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSNP-- 543
+ ID C+H +LC +G+C T S++C C+ GY+ GD C D++EC +
Sbjct: 1114 AAKDQCEDIDECQHR-HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 1172
Query: 544 CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICN 603
C GDC+NT GSY C C GFQ K C DI+EC G+ G C+NT+GSF C+C
Sbjct: 1173 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGPQGECLNTEGSFHCVCQ 1231
Query: 604 AGFELTTDGKNCVDHDECTTTNMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC 662
GF ++ DG+ C D DEC +C +G C N GSF+C+C GF +G+ C DV+EC
Sbjct: 1232 QGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC 1291
Query: 663 Q-TPGICMNGHCINSEGSFRC--------------DCPPGLAVGMDGRVCVDTHMRSTCY 707
+ G+C C N EGSF C C + +D V + CY
Sbjct: 1292 ELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECY 1351
Query: 708 GGIK-KGVCVRPFPGAVTKSECCCANPDYGFGEPCQ--PCPAKNSAEFHGLCSSGVGITV 764
+ +C VTK ECCC + G+G+ C+ PCP +AEF +C G G
Sbjct: 1352 YNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVP 1410
Query: 765 DG-----------RDINECAL-DPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 812
G +D +EC L +IC NG C N R Y C C G D C D+D
Sbjct: 1411 AGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMD 1470
Query: 813 ECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGS 872
EC + C +G C NT GSY+C C V + C I ESN +
Sbjct: 1471 EC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC--IRPAESNEQIEET------- 1520
Query: 873 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSR-CEVNING-ATLKSECCATLGAAWGS 930
D + CW ++ D C + G T +ECC G AWG
Sbjct: 1521 -------------------DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGM 1561
Query: 931 PCERCELDTA------C---------PRGLARIKGVTCE--------------------- 954
C C L + C P G + + +
Sbjct: 1562 QCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL 1621
Query: 955 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 998
EC + G C NGRCV + + C+C +G LD C+D+
Sbjct: 1622 QAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1664
Score = 349 bits (895), Expect = 3e-95
Identities = 270/920 (29%), Positives = 388/920 (42%), Gaps = 146/920 (15%)
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPD 802
P P + + E +S V +INEC ++PDIC G C NL Y C C GY
Sbjct: 849 PVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFS 908
Query: 803 ASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPC 861
R C+DIDEC + LC G C NT GS+ C CP G++ E C D++EC + C
Sbjct: 909 EQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVC 968
Query: 862 VNGACRNNLGSFNCE-CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCE---VNINGATLK 917
G C N +G+F CE C G +++ G RCE +N +T
Sbjct: 969 GEGHCVNTVGAFRCEYCDSGYRMTQRG------------------RCEDIDECLNPSTCP 1010
Query: 918 SECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGS 977
E C ++ +C C G G C DV+EC + P VC NG C N +GS
Sbjct: 1011 DEQCVNSPGSY-----QC---VPCTEGFRGWNG-QCLDVDEC-LEPNVCANGDCSNLEGS 1060
Query: 978 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 1037
+ C C +G T + C DI DEC C G TE
Sbjct: 1061 YMCSCHKGYTRTPDHKHCRDI-----------DEC---------QQGNLCVNGQCKNTE- 1099
Query: 1038 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFK 1097
+ C +G + D +DI+EC+ +C +G+CRNT GSF+
Sbjct: 1100 --------GSFRCTCGQGYQLSAAKDQC------EDIDECQ-HRHLCAHGQCRNTEGSFQ 1144
Query: 1098 CRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM 1157
C C+ G+ +C DI+EC +C G C+NT GS++C C +G++ K C
Sbjct: 1145 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--LDDNKTCQ 1202
Query: 1158 DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC-RNGKC 1216
DI+ECE L G C+NTEGSF C C G +S C DI+EC +++ +C +G C
Sbjct: 1203 DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFC 1261
Query: 1217 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSC---SEGY 1272
N G+++C C G+QA D QGC D++EC +++G C + C N EGS+ C C ++ Y
Sbjct: 1262 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEY 1321
Query: 1273 ALMPD---GRSCADID-----------ECE---NNPDICDGGQCTNIPGEYRCLCYDGFM 1315
+ M R+ D+D EC N+ +CD N+ + C C G
Sbjct: 1322 SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT-KQECCCTSG-- 1378
Query: 1316 ASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGA 1375
++ C + C KG F+ + S + G D DEC +
Sbjct: 1379 --AGWGDNCEIFPCPVLGTAEFTEMCPKGKG-FVPAGE--SSSEAGGENYKDADECLLFG 1433
Query: 1376 HNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ CLN ++C C++G + +K C D+DEC + + I+ QCVNT GSY
Sbjct: 1434 QEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS--SCIDGQCVNTEGSYN 1491
Query: 1434 CACSEGFTGDG--------------FTCSDV--DECAENIN---LCENGQCLNVPGAYRC 1474
C C+ D +DV D C E+++ +C C
Sbjct: 1492 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1551
Query: 1475 ECEMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLPGMFHCICD---------DGYEL- 1523
C G C D + +C + T P + D D Y +
Sbjct: 1552 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1611
Query: 1524 DRTGGNCTDI--DECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD-------- 1573
DR + ++ +EC C NG CV Y C+C + L+ + CVD
Sbjct: 1612 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1671
Query: 1574 NRVGNCYLKFGPRGDGSLSC 1593
NR+ C DGS C
Sbjct: 1672 NRMSLCKNAKCINTDGSYKC 1691
Score = 320 bits (821), Expect = 1e-86
Identities = 190/521 (36%), Positives = 244/521 (46%), Gaps = 52/521 (9%)
Query: 2253 DINECAQNPLLC-AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM 2311
+INEC NP +C A C+N Y C C GY E Q+ C D+DEC + H C S+G
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGR- 931
Query: 2312 CKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCE-CNEGFQ 2370
C+N G+F+CICP G +G C+D +EC +P +C G CVN +G++RCE C+ G++
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 990
Query: 2371 SSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGT 2430
+ G C D + L + C + S V C +G RGW QC
Sbjct: 991 MTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVP----CTEGFRGWNGQC-------- 1037
Query: 2431 AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2490
D+DEC + PN+C NG C N GS+ C C GYT C
Sbjct: 1038 -----------------LDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 1079
Query: 2491 DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 2550
D+DEC Q N CKNTEGS++C+C +GY L C+D+DECQ + C NT
Sbjct: 1080 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 1139
Query: 2551 LGGFTCKCPPGFTQHHTA--CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT 2608
G F C C G+ C D NEC S+C +G C NT GS+ C C GF LD
Sbjct: 1140 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLD-D 1197
Query: 2609 GLNCEDVDECDGNHRC--QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS 2666
C+D++EC+ C Q C N G + C C QG+ C D +EC N C S
Sbjct: 1198 NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDS 1257
Query: 2667 -ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPP- 2723
C NT GS++C C GF Q C DVNEC C C N EG +LC C
Sbjct: 1258 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 1317
Query: 2724 -GYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACY 2763
Y G C S LD +VD+ E Y
Sbjct: 1318 NQEYSPMTGQCRSRTS------TDLDVDVDQPKEEKKECYY 1352
Score = 218 bits (554), Expect = 9e-56
Identities = 111/326 (34%), Positives = 155/326 (47%), Gaps = 47/326 (14%)
Query: 2445 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY 2504
T +I+EC V P++C G CIN + C C GY C+D+DEC+Q C+
Sbjct: 870 TQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ 929
Query: 2505 -ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK------ 2557
C+NTEGS+ C CP G++ E+G C D+DEC + CVNT+G F C+
Sbjct: 930 GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 989
Query: 2558 ------------------------------------CPPGFTQHHTACIDNNECGSQPSL 2581
C GF + C+D +EC +P++
Sbjct: 990 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNV 1048
Query: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG-CQNILGGYRCGCP 2640
C A G C N GS+ C C +G++ +C D+DEC + C +G C+N G +RC C
Sbjct: 1049 C-ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 1107
Query: 2641 QGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECS 2700
QGY +QC D +EC + + C C NT GS++C C G+ C D+NEC
Sbjct: 1108 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL 1167
Query: 2701 SSKNPCNYG-CSNTEGGYLCGCPPGY 2725
K+ C G C NT G Y C CP G+
Sbjct: 1168 EDKSVCQRGDCINTAGSYDCTCPDGF 1193
Score = 209 bits (533), Expect = 2e-53
Identities = 217/841 (25%), Positives = 301/841 (35%), Gaps = 202/841 (24%)
Query: 124 CSRPNMCTCSSGQISSTCGSKSIQQCSV--------------RCMNGGTCADDHCQCQKG 169
C RP++C G +T G+ + C C+N TC D+ C G
Sbjct: 962 CLRPDVC--GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPG 1019
Query: 170 YIGTYCGQPVCE-----NG-CQNGGRCIGPNRCA---C--VYGFTGPQCERDYRTGPCFT 218
+Y P E NG C + C+ PN CA C + G C + Y P
Sbjct: 1020 ---SYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHK 1076
Query: 219 QVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDV 277
+ CQ G +C C T G C C +G+ + C+D+
Sbjct: 1077 HCRDIDECQ---QGNLCVNGQCKNTEG---SFRCT--------CGQGYQLSAAKDQCEDI 1122
Query: 278 DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNT 337
DECQ +C G C NT GSF+C C G++ S CEDI+EC +C+ G+C NT
Sbjct: 1123 DECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 1181
Query: 338 VGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
GSY C CP G+ D C D + G+C G C C C+ G
Sbjct: 1182 AGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGP---QGECL----NTEGSFHCVCQQG 1233
Query: 394 --------RCWGIGTIPE--ACPVRG-----SEEYRRLCMDGLP-----MGGIPGSAGSR 433
C I C G + +R LC G G + +
Sbjct: 1234 FSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECEL 1293
Query: 434 PGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNG--FSPGVGGAGVGAGGQGPIITGLTIL 491
G G F + G+ F+ + +SP G T L
Sbjct: 1294 LSGVCGEAFCENVEGS--------FLCVCADENQEYSPMTGQCRSRTS---------TDL 1336
Query: 492 NQTIDICKHHANLC---LNGRCI------PTVSSYRCECNMGYKQDANGDCIDVDECTSN 542
+ +D K C LN + P V+ C C G D C
Sbjct: 1337 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWG--------DNCEIF 1388
Query: 543 PCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI--------DIDECIQNG-VLCKNGRCVN 593
PC V + C G P ++ D DEC+ G +CKNG C+N
Sbjct: 1389 PCP----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN 1444
Query: 594 TDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNG 653
T ++C C G C D DEC + C++G C+N +GS+ C C VL +
Sbjct: 1445 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE 1504
Query: 654 RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG 713
+ C E + I ++ C L+ +
Sbjct: 1505 KRCIRPAE--------SNEQIEETDVYQDLCWEHLS---------------------DEY 1535
Query: 714 VCVRPFPG-AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR----- 767
VC RP G T +ECCC + +G C CP K+S ++ LC+ I V GR
Sbjct: 1536 VCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCN----IPVTGRRQPYG 1590
Query: 768 -------------------------------DINECALDPDICANGICENLRGSYRCNCN 796
EC + + C NG C ++ Y C+C
Sbjct: 1591 RDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCF 1649
Query: 797 SGYEPDASGRNCIDIDEC--LVNRL-LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDI 853
GY D + C+D++EC L NR+ LC N C NT GSY C C PGYV + C +
Sbjct: 1650 DGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPL 1709
Query: 854 N 854
N
Sbjct: 1710 N 1710
Score = 159 bits (402), Expect = 4e-38
Identities = 178/745 (23%), Positives = 257/745 (34%), Gaps = 167/745 (22%)
Query: 62 EYREEGAAVASRVRRRGQQDVLRGPNVC---------GSRFHSYCCPGWKTLPGG----N 108
EY + G + R R + L P+ C GS C G++ G +
Sbjct: 983 EYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVD 1041
Query: 109 QCIVPICRNSCGDGFCSRPN---MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQ 165
+C+ P N C +G CS MC+C G + T K + C G C + C+
Sbjct: 1042 ECLEP---NVCANGDCSNLEGSYMCSCHKGY-TRTPDHKHCRDID-ECQQGNLCVNGQCK 1096
Query: 166 CQKGYIGTYCGQPV--------CEN--GCQNGGRCI--------GPNRCACVYGFT---- 203
+G CGQ CE+ CQ+ C G +C C G+
Sbjct: 1097 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 1156
Query: 204 GPQCE---------RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMC 254
G CE + G C + C G C I HP +C
Sbjct: 1157 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQDINEC-EHP-GLC 1213
Query: 255 PAQPQ----------PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCP 304
Q + C++GF + C+D+DEC G C NT GSF C C
Sbjct: 1214 GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCY 1273
Query: 305 AGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP---RGYV---------TS 352
G + + Q C D++EC ++ G+C C N GS+ CVC + Y TS
Sbjct: 1274 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTS 1333
Query: 353 TDGSRCIDQ---RTGMCFSGLVNGR-CAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVR 408
TD +DQ C+ L + C L +TK +CCC G WG CPV
Sbjct: 1334 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVL 1393
Query: 409 GSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFS 468
G+ E+ +C P G GF+P
Sbjct: 1394 GTAEFTEMC-----------------------------------PKGKGFVP-------- 1410
Query: 469 PGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMG-YKQ 527
G + AGG+ + +C NG C+ T Y C C G Y
Sbjct: 1411 --AGESSSEAGGEN--------YKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1460
Query: 528 DANGDCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI---DIDECIQNG 583
C D+DEC + C +G CVNT GSY C C +++ CI + +E I+
Sbjct: 1461 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET 1520
Query: 584 VLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCIC 643
+ ++ + + C + TT + C + E L + ++D + C
Sbjct: 1521 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1580
Query: 644 KPGFVLAPNGR---------YCTDVD------------------ECQTPGICMNGHCINS 676
P GR Y + D EC C NG C+
Sbjct: 1581 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV 1640
Query: 677 EGSFRCDCPPGLAVGMDGRVCVDTH 701
+ + CDC G + CVD +
Sbjct: 1641 QEGYTCDCFDGYHLDTAKMTCVDVN 1665
Score = 152 bits (383), Expect = 6e-36
Identities = 144/559 (25%), Positives = 204/559 (36%), Gaps = 119/559 (21%)
Query: 86 PNVCGSR---------FHSYCCPGWKTLPGGNQCI-VPICRNSCGDGFCSRPNMCTCSSG 135
P +CG + FH C G+ G C + C N+ C C ++G
Sbjct: 1210 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT---VCDSHGFCDNTAG 1266
Query: 136 QISSTCGSKSIQQCSVRCMNGGTCAD-DHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPN 194
C Q +G C D + C+ G CG+ CEN + C+ +
Sbjct: 1267 SFRCLC-----YQGFQAPQDGQGCVDVNECELLSGV----CGEAFCEN-VEGSFLCVCAD 1316
Query: 195 RCACVYGFTGPQCERDYRTG-------------PCFTQVNN-QMCQGQLTGIVCTKTLCC 240
TG QC T C+ +N+ +C L V TK CC
Sbjct: 1317 ENQEYSPMTG-QCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV-TKQECC 1374
Query: 241 ATIGRAWGHPCEMCPA---------QPQPCRRGFIPNIRTGA------CQDVDECQAI-P 284
T G WG CE+ P + P +GF+P + + +D DEC
Sbjct: 1375 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1434
Query: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
IC+ G C+NT +EC C G +C D+DEC P C G+C NT GSY C
Sbjct: 1435 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCF 1493
Query: 345 CPRGYVTSTDGSRCI------------DQRTGMCFSGLVNGR-CAQELPGRMTK-MQCCC 390
C V RCI D +C+ L + C++ L G+ T +CCC
Sbjct: 1494 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC 1553
Query: 391 EPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNG 450
G WG+ CP++ S++Y +LC IP + +P G A
Sbjct: 1554 LYGEAWGMQC--ALCPLKDSDDYAQLC-------NIPVTGRRQPYGRD----ALVDFSEQ 1600
Query: 451 YGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANL---CLN 507
Y P P LN ++ + C N
Sbjct: 1601 YTPEA--------------------------DPYFIQDRFLNSFEELQAEECGILNGCEN 1634
Query: 508 GRCIPTVSSYRCECNMGYKQD-ANGDCIDVDECTS-----NPCTNGDCVNTPGSYYCKCH 561
GRC+ Y C+C GY D A C+DV+EC + C N C+NT GSY C C
Sbjct: 1635 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1694
Query: 562 AGFQRTPTKQACIDIDECI 580
G+ + C ++ +
Sbjct: 1695 PGYVPSDKPNYCTPLNTAL 1713
Score = 132 bits (333), Expect = 4e-30
Identities = 69/202 (34%), Positives = 103/202 (50%), Gaps = 19/202 (9%)
Query: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWG-SPCERCELDTA---------CPRGL 945
G C+ S+C + G + + +CC T+G +WG + C++C + C G
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 616
Query: 946 ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD----IRME 1001
R+ C+D+NEC++ GVCPNG C+N+ GS+ C C G D T C+ I E
Sbjct: 617 KRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEE 675
Query: 1002 Q--CY-LKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
+ CY L +C+HP+ CCC+VG AWG CE+CP PGT ++ +CP G G+
Sbjct: 676 KGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 735
Query: 1059 ANRGDVLTGRPFYKDINECKAF 1080
G V RP + + + F
Sbjct: 736 TVSG-VHRRRPIHHHVGKGPVF 756
Score = 108 bits (269), Expect = 1e-22
Identities = 57/134 (42%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 2320 MCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC- 2378
M C PG +R + C D NEC+ + G+C NG C+N +GSYRC C GF + + C
Sbjct: 609 MMECLPGY-KRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 666
Query: 2379 -----LDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 2433
+ +G C+ V M S +L TK CCC G+ WG CE CPLPGTA +
Sbjct: 667 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHL-TKQLCCCSVGKAWGPHCEKCPLPGTAAF 725
Query: 2434 KKICPHGPGYTTDG 2447
K+ICP G GYT G
Sbjct: 726 KEICPGGMGYTVSG 739
Score = 101 bits (252), Expect = 9e-21
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 49/202 (24%)
Query: 1603 RSSCCCSLGKAWG-NPCETCPPVNSTEYYT----LCPGGEGFRPNPITIILEDIDECQEL 1657
+ CC ++G +WG N C+ CP S Y PG + R N +DI+ECQ L
Sbjct: 578 QEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK--RVN--NTFCQDINECQ-L 632
Query: 1658 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTC 1717
G+C G C+NT GS++C C G+ GP ++ +C
Sbjct: 633 QGVCPNGECLNTMGSYRCTCKIGF----------------------GPDPTFS-----SC 665
Query: 1718 ICPPEYMQVNGGHNCMDMRKSFCYRSY-NGTTCENELPFNVTKRMCCCTYNVGKAWNKPC 1776
+ P + G CYR +G C + L ++TK++CCC +VGKAW C
Sbjct: 666 VPDPPVISEEKGP---------CYRLVSSGRQCMHPLSVHLTKQLCCC--SVGKAWGPHC 714
Query: 1777 EPCPTPGTADFKTICGNIPGFT 1798
E CP PGTA FK IC G+T
Sbjct: 715 EKCPLPGTAAFKEICPGGMGYT 736
Score = 96.3 bits (238), Expect = 4e-19
Identities = 58/218 (26%), Positives = 87/218 (39%), Gaps = 51/218 (23%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQ--------PCRRG 264
G CF + C L G+ + CC T+G +WG + C+ CP +P C G
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG 615
Query: 265 FIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSI 324
+ + CQD++ECQ + G+C G C+NT+GS+ C C G T C
Sbjct: 616 Y-KRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC-------- 665
Query: 325 IPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGR-CAQELPGRM 383
I + G C+ + +GR C L +
Sbjct: 666 ----------------------------VPDPPVISEEKGPCYRLVSSGRQCMHPLSVHL 697
Query: 384 TKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGL 421
TK CCC G+ WG E CP+ G+ ++ +C G+
Sbjct: 698 TKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGM 733
Score = 90.1 bits (222), Expect = 3e-17
Identities = 45/130 (34%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 643 CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--- 699
C PG+ N +C D++ECQ G+C NG C+N+ GS+RC C G CV
Sbjct: 612 CLPGYKRV-NNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 700 --THMRSTCYGGIKKG-VCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC 756
+ + CY + G C+ P +TK CCC + +G C+ CP +A F +C
Sbjct: 671 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCC-SVGKAWGPHCEKCPLPGTAAFKEIC 729
Query: 757 SSGVGITVDG 766
G+G TV G
Sbjct: 730 PGGMGYTVSG 739
Score = 86.7 bits (213), Expect = 3e-16
Identities = 67/200 (33%), Positives = 88/200 (44%), Gaps = 30/200 (15%)
Query: 1988 GRCFNE-IGSFKCLCNEGYELTPDGKNCIDT-------NECVALPGSCS-PGTCQNLEGS 2038
GRCF E IGS C + ++C T N+C P S G Q +E
Sbjct: 557 GRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME-- 611
Query: 2039 FRCICPPGYE-VKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC- 2096
C PGY+ V + C DINEC +C G C NT G ++C C GF C
Sbjct: 612 ----CLPGYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 666
Query: 2097 -----FDTRQSFCFTNFENGK-CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
+ C+ +G+ C P + + TK CCCS G+ WG CE CP A
Sbjct: 667 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV--GKAWGPHCEKCPLPGTAA 724
Query: 2151 FQDLCPYGHG-TVPSLHDTR 2169
F+++CP G G TV +H R
Sbjct: 725 FKEICPGGMGYTVSGVHRRR 744
Score = 86.3 bits (212), Expect = 4e-16
Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDN------RVGNCYLKF 1583
C DI+EC C NG C+NT G Y C C F +PT CV + G CY
Sbjct: 624 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 683
Query: 1584 GPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
C + V +++ CCCS+GKAWG CE CP + + +CPGG G+
Sbjct: 684 S----SGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 735
Score = 80.1 bits (196), Expect = 3e-14
Identities = 46/126 (36%), Positives = 69/126 (54%), Gaps = 10/126 (7%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPL-PGTAQYKKICPHGP 2441
G CF E + + C A L + +CC G WG ++C+ CP P Y ++ P
Sbjct: 557 GRCFQETIGSQCGKALPG--LSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 614
Query: 2442 GY----TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI-DLDECS 2496
GY T +DI+EC++ +C NG+C+NTMGS+RC CK+G+ D + +SC+ D S
Sbjct: 615 GYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 673
Query: 2497 QSPKPC 2502
+ PC
Sbjct: 674 EEKGPC 679
Score = 75.5 bits (184), Expect = 7e-13
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 945 LARIKGVTCEDVNECEVFPG---VCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
++RI G T + E + PG V G V + H + V ++
Sbjct: 500 VSRIDGPTGQKTKEAQ--PGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG 557
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWG-TECEECPK-PGTKEYETLCPRGAGFA 1059
+C+ + +C +PG + + CC VG +WG +C++CPK P Y + G+
Sbjct: 558 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK 617
Query: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 1113
F +DINEC+ G+C G+C NT+GS++C C GF D +C
Sbjct: 618 R-----VNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 74.7 bits (182), Expect = 1e-12
Identities = 45/139 (32%), Positives = 57/139 (41%), Gaps = 18/139 (12%)
Query: 30 PQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQ---------- 79
P PPPP+P RP P Q+ G AP ++ V S+V + Q
Sbjct: 101 PPPPPPEPARPAVPGGQLHPNPGGHPAA--APFTKQGRQVVRSKVPQETQSGGGSRLQVH 158
Query: 80 -QDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSC-GDGFCSRPNMCTCSSGQI 137
+ L+G NVCG R CC GW PG +C P C C G C RP +C C G
Sbjct: 159 QKQQLQGVNVCGGR----CCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQLCVCKPGTK 214
Query: 138 SSTCGSKSIQQCSVRCMNG 156
C + + Q S G
Sbjct: 215 GKACETIAAQDTSSPVFGG 233
Score = 64.3 bits (155), Expect = 2e-09
Identities = 62/239 (25%), Positives = 83/239 (34%), Gaps = 81/239 (33%)
Query: 715 CVRPFPGAVTKSECC-CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECA 773
C + PG + +CC +GF + CQ CP K S +HG
Sbjct: 568 CGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPS--YHGY------------------ 606
Query: 774 LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSY 833
N + E L G R N C DI+EC + + C NG C NT GSY
Sbjct: 607 -------NQMMECLPGYKRVN----------NTFCQDINECQLQGV-CPNGECLNTMGSY 648
Query: 834 SCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDS 893
CTC G+ + C +P V I
Sbjct: 649 RCTCKIGF------GPDPTFSSCVPDPPV----------------------------ISE 674
Query: 894 LKGTCWLNIQDSR-CEVNINGATLKSECCATLGAAWGSPCERCEL------DTACPRGL 945
KG C+ + R C ++ K CC ++G AWG CE+C L CP G+
Sbjct: 675 EKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGM 733
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 1740 CYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPT-PGTADFKTICGNIPGFT 1798
C++ G+ C LP + CC T +NK C+ CP P + + +PG+
Sbjct: 559 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPSYHGYNQMMECLPGYK 617
Query: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC 1848
++ DI+EC ++ G+C NG C+N +GS+RC C GF + C
Sbjct: 618 -RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 60.8 bits (146), Expect = 2e-08
Identities = 52/201 (25%), Positives = 74/201 (36%), Gaps = 54/201 (26%)
Query: 520 ECNMGYKQDANGDCIDVDECT-SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDE 578
EC GYK+ N C D++EC C NG+C+NT GSY C C GF PT +C+
Sbjct: 611 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 579 CIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS 638
I + G C + L + G+ C+ T
Sbjct: 671 VISE----EKGPC--------------YRLVSSGRQCMHPLSVHLTKQL----------- 701
Query: 639 FKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV 698
C C G P+ ++C PG +F+ CP G+ + G
Sbjct: 702 --CCCSVGKAWGPH------CEKCPLPG----------TAAFKEICPGGMGYTVSG---- 739
Query: 699 DTHMRSTCYGGIKKG-VCVRP 718
H R + + KG V V+P
Sbjct: 740 -VHRRRPIHHHVGKGPVFVKP 759
Score = 58.9 bits (141), Expect = 7e-08
Identities = 49/168 (29%), Positives = 69/168 (41%), Gaps = 28/168 (16%)
Query: 109 QCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQK 168
+C + CG C G + ++ G Q+C + G + +C
Sbjct: 558 RCFQETIGSQCGKALPGLSKQEDCC-GTVGTSWGFNKCQKCPKKPSYHGY--NQMMECLP 614
Query: 169 GYI---GTYCG-------QPVCENG-CQNGGRCIGPNRCACVYGF----TGPQCERD--- 210
GY T+C Q VC NG C N +G RC C GF T C D
Sbjct: 615 GYKRVNNTFCQDINECQLQGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPV 671
Query: 211 --YRTGPCFTQVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
GPC+ V++ + C L+ + TK LCC ++G+AWG CE CP
Sbjct: 672 ISEEKGPCYRLVSSGRQCMHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 718
Score = 52.8 bits (125), Expect = 5e-06
Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 2652 CVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD-QFSSACHDVNECSSSKNPC 2706
C D NEC C + C NT+GSY+C C GF D FSS D S K PC
Sbjct: 624 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 679
Score = 51.6 bits (122), Expect = 1e-05
Identities = 63/245 (25%), Positives = 86/245 (35%), Gaps = 69/245 (28%)
Query: 2099 TRQSFCFTNFENGKCSVPKAF-NTTKAKCCCSKMPGEGWG-DPCELCPKDDEVAFQDLCP 2156
T+ CF +C KA +K + CC + G WG + C+ CPK
Sbjct: 554 TQLGRCFQETIGSQCG--KALPGLSKQEDCCGTV-GTSWGFNKCQKCPKK---------- 600
Query: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
PS H + + EC GY C D +E
Sbjct: 601 ------PSYHGYNQMM------------------------ECLPGYKR-VNNTFCQDINE 629
Query: 2217 CSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR---CMNTFG 2273
C + C NG C N +GS+ C C GF P P + C +P + + C
Sbjct: 630 CQLQGVCPNGECLNTMGSYRCTCKIGFGPDP-----TFSSCVPDPPVISEEKGPCYRLVS 684
Query: 2274 S-YECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKN--LIGT--FMCICPPGMA 2328
S +C P+ L K L C+ G ++ G C+ L GT F ICP GM
Sbjct: 685 SGRQCMHPLSVHL------TKQLCCCSVG----KAWGPHCEKCPLPGTAAFKEICPGGMG 734
Query: 2329 RRPDG 2333
G
Sbjct: 735 YTVSG 739
Score = 51.6 bits (122), Expect = 1e-05
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 1857 GDNLCQRNADCINSPGSY----RCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
G N CQ+ C P + EC G+K N C D NEC ++ VC +G C++
Sbjct: 590 GFNKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTM 645
Query: 1913 GSYQCICHNGFKASQDQTMCM---DVDECERHPC 1943
GSY+C C GF + C+ V E+ PC
Sbjct: 646 GSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 679
Score = 50.1 bits (118), Expect = 3e-05
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 1447 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
C D++EC +C NG+CLN G+YRC C++GF P SC
Sbjct: 624 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 48.5 bits (114), Expect = 9e-05
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 27/135 (20%)
Query: 1067 GRPFYKDI-NEC-KAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPD 1124
GR F + I ++C KA PG+ C T+G+ + GF +C P
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-----SWGF---------NKCQKCPKKPS 602
Query: 1125 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCD 1184
G + EC GY+ + C DI+EC+ + C G C+NT GS++C
Sbjct: 603 YHGYNQMM--------ECLPGYKR--VNNTFCQDINECQLQGV-CPNGECLNTMGSYRCT 651
Query: 1185 CPLGHELSPSREDCV 1199
C +G P+ CV
Sbjct: 652 CKIGFGPDPTFSSCV 666
Score = 46.2 bits (108), Expect = 5e-04
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 29/139 (20%)
Query: 1919 CHNGFKASQDQTMCMDVDECE-RHPCGNGTCKNTVGSYNCLCYPGF--ELTHNNDCLD-- 1973
C G+K + T C D++EC+ + C NG C NT+GSY C C GF + T ++ D
Sbjct: 612 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 1974 --IDECSSFFGQVCRNGRCFNEIG----SFKCLCNEGYELTPDGKNCIDTNECVALPGSC 2027
+E + V +C + + C C+ G P + C LPG+
Sbjct: 671 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC-------PLPGT- 722
Query: 2028 SPGTCQNLEGSFRCICPPG 2046
+F+ ICP G
Sbjct: 723 ---------AAFKEICPGG 732
Score = 45.4 bits (106), Expect = 8e-04
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 34/141 (24%)
Query: 1813 KEIPGICANGVCINQIGSF----RCE-CPTGFSY---NDLL-----------LVCEDIDE 1853
K +PG+ C +G+ +C+ CP SY N ++ C+DI+E
Sbjct: 570 KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINE 629
Query: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN-GACV--------DRNECLEIPN--- 1901
C +C N +C+N+ GSYRC C GF P +CV ++ C + +
Sbjct: 630 CQL-QGVCP-NGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGR 687
Query: 1902 VCSHGLCVDLQGSYQCICHNG 1922
C H L V L C C G
Sbjct: 688 QCMHPLSVHLT-KQLCCCSVG 707
Score = 45.4 bits (106), Expect = 8e-04
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTY----QCSCNPGYQATPDRQGCTDIDECMIMN 1250
+EDC S N C+ KC + C PGY+ + C DI+EC +
Sbjct: 578 QEDCCGTVGTSWGFNKCQ--KCPKKPSYHGYNQMMECLPGYKRV-NNTFCQDINECQLQG 634
Query: 1251 GGCDTQCTNSEGSYECSCSEGYALMPDGRSC 1281
+ +C N+ GSY C+C G+ P SC
Sbjct: 635 VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 45.1 bits (105), Expect = 0.001
Identities = 36/134 (26%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 2557 KCPPGFTQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC--- 2612
+C PG+ + ++T C D NEC Q +C G C NT GS+ C C+ GF D T +C
Sbjct: 611 ECLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 668
Query: 2613 -----EDVDEC----DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2663
E+ C +C H L C C G +C +
Sbjct: 669 PPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEI 728
Query: 2664 CGSASCYNTLGSYK 2677
C Y G ++
Sbjct: 729 CPGGMGYTVSGVHR 742
Score = 43.9 bits (102), Expect = 0.002
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 23/140 (16%)
Query: 43 PPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWK 102
P Q+ S +EG F +++ AA G+ V+ P++C
Sbjct: 315 PAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVT---------- 364
Query: 103 TLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQ--CSVRCMNGGTCA 160
C C+NSC G +G + T + + + C + CMNGG C+
Sbjct: 365 -------CTKGSCQNSCEKG---NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCS 414
Query: 161 D-DHCQCQKGYIGTYCGQPV 179
D CQC + G C PV
Sbjct: 415 SRDKCQCPPNFTGKLCQIPV 434
Score = 43.5 bits (101), Expect = 0.003
Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1323 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC 1365
C D+NEC L +C GEC NT GS+ C C++G+ + C
Sbjct: 624 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 43.1 bits (100), Expect = 0.004
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
C GY + + C DI+EC+ +C G+C N G YRC C GF +C+
Sbjct: 612 CLPGYKRV-NNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 666
Score = 42.4 bits (98), Expect = 0.007
Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 2454 KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSY 2513
K +P L C T+G+ F K C + PK +Y N
Sbjct: 570 KALPGLSKQEDCCGTVGTSWGFNK-----------------CQKCPKKPSYHGYNQ---- 608
Query: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHT--ACID 2571
C GY + + C+D++ECQ + C+NT+G + C C GF T +C+
Sbjct: 609 MMECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP 667
Query: 2572 NNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECDGNH 2622
+ P + KG C S +C S+ T L C V + G H
Sbjct: 668 D-----PPVISEEKGPCYRLVSS-GRQCMHPLSVHLTKQLCCCSVGKAWGPH 713
Score = 41.2 bits (95), Expect = 0.015
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDV-------DECA 1454
N C D++EC N +C+NT GSYRC C GF D S V +E
Sbjct: 620 NNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG 677
Query: 1455 ENINLCENG-QCLNVPGAY----RCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNL 1509
L +G QC++ + C C +G C +F+ IC G +
Sbjct: 678 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV 737
Query: 1510 PGM 1512
G+
Sbjct: 738 SGV 740
Score = 38.5 bits (88), Expect = 0.098
Identities = 62/290 (21%), Positives = 93/290 (32%), Gaps = 64/290 (22%)
Query: 158 TCADDHCQ--CQKGYIGTYCGQP---------------VCENGCQNGGRCIGPNRCACVY 200
TC CQ C+KG T + +C C NGG+C ++C C
Sbjct: 364 TCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCP- 422
Query: 201 GFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATI-GRAWG-------HPCE 252
P FT ++CQ + G K + G+A G H
Sbjct: 423 --------------PNFT---GKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLP 465
Query: 253 MCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSET 312
+ Q + F PNI + E I+ V + P G K E
Sbjct: 466 LTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ---------IHQVSRIDG--PTGQKTKEA 514
Query: 313 TQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVN 372
+ + +T ++ S+ V P Y + + G CF +
Sbjct: 515 QPGQSQVSYQGLPVQKTQT---IHSTYSHQQVIPHVYPVAAK------TQLGRCFQETIG 565
Query: 373 GRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLP 422
+C + LPG + CC G WG + CP + S M+ LP
Sbjct: 566 SQCGKALPGLSKQEDCCGTVGTSWGFNKC-QKCPKKPSYHGYNQMMECLP 614
Score = 35.8 bits (81), Expect = 0.64
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1399
C GY + T C D++EC++ + CLN GS++C+C+ G+
Sbjct: 612 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 656
Score = 35.8 bits (81), Expect = 0.64
Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQD 528
Q I+ C+ +C NG C+ T+ SYRC C +G+ D
Sbjct: 625 QDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPD 659
Score = 34.7 bits (78), Expect = 1.4
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 2498 SPKPCNYICKNTEGSYQCSCPRGY---VLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
+P C C T+GS Q SC +G ++ E+G L + C C+N GG
Sbjct: 357 TPSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQ 412
Query: 2555 T-----CKCPPGFT 2563
C+CPP FT
Sbjct: 413 CSSRDKCQCPPNFT 426
Score = 33.1 bits (74), Expect = 4.1
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 2693 CHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
C D+NEC N C NT G Y C C G+
Sbjct: 624 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 472 bits (1215), Expect = e-132
Identities = 288/891 (32%), Positives = 411/891 (46%), Gaps = 128/891 (14%)
Query: 1894 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNT 1951
NEC P++C G C++L Y CIC+ G++ S+ Q C+D+DEC + H C G C+NT
Sbjct: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 609
Query: 1952 VGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGRCFNEIGSFKC-LCNEGYELTP 2009
GS+ C+C GF + +C+D+DEC VC G C N +G+F+C C+ GY +T
Sbjct: 610 EGSFLCICPAGFMASEEGTNCIDVDECLR--PDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
Query: 2010 DGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI-CPPGYEVKSENCIDINECDEDPNICL 2068
G+ C D +EC+ P +C C N GS++C+ C G+ + C+D++EC E PN+C
Sbjct: 668 RGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCA 724
Query: 2069 FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2128
G C+N G + C C G+ + + + C D + NG+C
Sbjct: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQC--------------- 769
Query: 2129 SKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCI 2188
K+ E +F+ C G+ + + D ED++EC + +C++GQC
Sbjct: 770 ----------------KNTEGSFRCTCGQGY-QLSAAKDQCEDIDEC-QHRHLCAHGQCR 811
Query: 2189 NTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFECNCNEGFEPGP 2247
NT+GSF+C C GY G C D +EC + C G C N GS++C C +GF+
Sbjct: 812 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD 871
Query: 2248 MMNCEDINECAQNPLLCAFR--CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
C+DINEC ++P LC + C+NT GS+ C C G+++ D + C+D+DEC C
Sbjct: 872 NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV-C 929
Query: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2365
+S G C N G+F C+C G DG+GCVD NEC G+C C N+ GS+ C C
Sbjct: 930 DSHGF-CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 988
Query: 2366 NEGFQSSSSGT-ECLDNRQGLCFAEVLQTICQMASSSRNL-------------VTKSECC 2411
+ Q S T +C +V Q + NL VTK ECC
Sbjct: 989 ADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC 1048
Query: 2412 CDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG-----------RDIDECKVM-P 2457
C G GWG CE+ CP+ GTA++ ++CP G G+ G +D DEC +
Sbjct: 1049 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1108
Query: 2458 NLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCS 2516
+C NG C+NT + C+CK G D C D+DEC Q P C + C NTEGSY C
Sbjct: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCF 1167
Query: 2517 CPRGYVLQEDGKTC-------KDLDECQTKQHNC------QFLCVNTLGGFTCKCPPGFT 2563
C VL K C + ++E Q C +++C L G T
Sbjct: 1168 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT------T 1221
Query: 2564 QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR 2623
C+ G Q +LC K S + + ++ TG R
Sbjct: 1222 YTECCCLYGEAWGMQCALCPLKD---------SDDYAQLCNIPVTG------------RR 1260
Query: 2624 CQHGCQNILGGYRCGCPQG---YIQHYQWNQC--VDENECSNPNACGSASCYNTLGSYKC 2678
+G ++ P+ +IQ N + EC N C + C Y C
Sbjct: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC 1320
Query: 2679 ACPSGFSFDQFSSACHDVNECSSSKNPC----NYGCSNTEGGYLCGCPPGY 2725
C G+ D C DVNEC N N C NT+G Y C C PGY
Sbjct: 1321 DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
Score = 467 bits (1202), Expect = e-131
Identities = 283/864 (32%), Positives = 409/864 (47%), Gaps = 144/864 (16%)
Query: 1158 DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCV 1217
+I+EC NP +C G C+N + C C G+ S + CVDI+EC+ +LC G+C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 1218 NMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS-CSEGYALMP 1276
N G++ C C G+ A+ + C D+DEC+ + + C N+ G++ C C GY +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
Query: 1277 DGRSCADIDECENNPDICDGGQCTNIPGEYRCL-CYDGFMASMDMKTCIDVNECDLNSNI 1335
GR C DIDEC NP C QC N PG Y+C+ C +GF C+DV+EC L N+
Sbjct: 668 RGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDEC-LEPNV 722
Query: 1336 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
C G+C N +GS++C C GY+ C D+DEC+ G N ++ C N GSF+C+C
Sbjct: 723 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG--NLCVNGQCKNTEGSFRCTC 780
Query: 1396 REGWIGNGIK--CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSDVD 1451
+G+ + K C D+DEC + H C+ + QC NT GS++C C +G+ +G G C D++
Sbjct: 781 GQGYQLSAAKDQCEDIDECQH-RHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCEDIN 838
Query: 1452 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLP 1510
EC E+ ++C+ G C+N G+Y C C GF D+++CQDI+EC +C G C N
Sbjct: 839 ECLEDKSVCQRGDCINTAGSYDCTCPDGF-QLDDNKTCQDINECEHPGLCGPQGECLNTE 897
Query: 1511 GMFHCICDDGYELDRTGGNCTDIDECADPINC-VNGLCVNTPGRYECNCPPDFQLNPTGV 1569
G FHC+C G+ + G C DIDEC + C +G C NT G + C C FQ G
Sbjct: 898 GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 957
Query: 1570 GCVDNRVGNCYLKFGPRG-------DGSLSC--------------------NTEIGV--- 1599
GCVD V C L G G +GS C +T++ V
Sbjct: 958 GCVD--VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
Query: 1600 -------------------------GVSRSSCCCSLGKAWGNPCE--TCPPVNSTEYYTL 1632
V++ CCC+ G WG+ CE CP + + E+ +
Sbjct: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
Query: 1633 CPGGEGFRPNPITII------LEDIDEC----QELPGLCQGGNCINTFGSFQCECPQGYY 1682
CP G+GF P + +D DEC QE +C+ G C+NT ++C C QG Y
Sbjct: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQE---ICKNGFCLNTRPGYECYCKQGTY 1132
Query: 1683 LSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM--------- 1733
C D+DEC P C G C NT G+Y C C + C+
Sbjct: 1133 YDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1191
Query: 1734 ---DMRKSFCYRSYNGT-TCENEL-PFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFK 1788
D+ + C+ + C L T CCC Y G+AW C CP + D+
Sbjct: 1192 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYA 1249
Query: 1789 TICGNI--------------------------PGFTFD--IHTGKAVDIDECKEIPGICA 1820
+C NI P F D +++ + + +EC + G C
Sbjct: 1250 QLC-NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CE 1307
Query: 1821 NGVCINQIGSFRCECPTGFSYNDLLLVCEDIDEC---SNGDNLCQRNADCINSPGSYRCE 1877
NG C+ + C+C G+ + + C D++EC +N +LC +NA CIN+ GSY+C
Sbjct: 1308 NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLC-KNAKCINTDGSYKCL 1366
Query: 1878 CAAGFKLS--PNGACVDRNECLEI 1899
C G+ S PN C N L +
Sbjct: 1367 CLPGYVPSDKPN-YCTPLNTALNL 1389
Score = 456 bits (1172), Expect = e-127
Identities = 294/856 (34%), Positives = 394/856 (46%), Gaps = 99/856 (11%)
Query: 1283 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1342
+I+EC NPDIC G C N+P Y C+CY+G+ S + C+D++EC ++C G CE
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 1343 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-CREGW-I 1400
NT+GSF+C C G+ + T C DVDEC + C C+N G+F+C C G+ +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCG-EGHCVNTVGAFRCEYCDSGYRM 665
Query: 1401 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCA-CSEGFTGDGFTCSDVDECAENINL 1459
+C D+DEC N + C + QCVN+PGSY+C C+EGF G C DVDEC E N+
Sbjct: 666 TQRGRCEDIDECLNPS-TCP-DEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-NV 722
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
C NG C N+ G+Y C C G+T D + C+DIDEC N+CV G C N G F C C
Sbjct: 723 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQ 782
Query: 1520 GYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC 1579
GY+L C DIDEC C +G C NT G ++C C ++ + G C D + C
Sbjct: 783 GYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INEC 840
Query: 1580 Y--LKFGPRGD-----GSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE---TCPPVN---S 1626
RGD GS C G + + C + N CE C P +
Sbjct: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI-----NECEHPGLCGPQGECLN 895
Query: 1627 TEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSED 1686
TE C +GF + EDIDEC G C NT GSF+C C QG+ +D
Sbjct: 896 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQD 955
Query: 1687 TRICEDIDECFAHPGVCGPGTCYNTLGNYTCICP---PEYMQVNG---GHNCMDM----- 1735
+ C D++EC GVCG C N G++ C+C EY + G D+
Sbjct: 956 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
Query: 1736 ----RKSFCYRSYN-GTTCENELPFNVTKRMCCCTYNVGKAWNKPCE--PCPTPGTADFK 1788
K CY + N + C+N L NVTK+ CCCT G W CE PCP GTA+F
Sbjct: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG--WGDNCEIFPCPVLGTAEFT 1073
Query: 1789 TIC----GNIPGFTFDIHTG--KAVDIDECKEI-PGICANGVCINQIGSFRCECPTGFSY 1841
+C G +P G D DEC IC NG C+N + C C G Y
Sbjct: 1074 EMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYY 1133
Query: 1842 NDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL-SPNGACV---DRNECL 1897
+ + L C D+DEC + + + C+N+ GSY C C L + C+ + NE +
Sbjct: 1134 DPVKLQCFDMDECQDPSSCI--DGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1191
Query: 1898 EIPN--------------VCSHGLCVDLQGSY-QCICHNGFKASQDQTMC--MDVDEC-- 1938
E + VCS L V Q +Y +C C G +C D D+
Sbjct: 1192 EETDVYQDLCWEHLSDEYVCSRPL-VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
Query: 1939 --------ERHPCGNGTCKNTVGSYNCLCYPGF---ELTHNNDCLDIDECSSFFGQVCRN 1987
R P G + Y P F ++ + L +EC G C N
Sbjct: 1251 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG--CEN 1308
Query: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGS---CSPGTCQNLEGSFRCICP 2044
GRC + C C +GY L C+D NEC L C C N +GS++C+C
Sbjct: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
Query: 2045 PGY--EVKSENCIDIN 2058
PGY K C +N
Sbjct: 1369 PGYVPSDKPNYCTPLN 1384
Score = 416 bits (1069), Expect = e-115
Identities = 279/877 (31%), Positives = 392/877 (44%), Gaps = 124/877 (14%)
Query: 535 DVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCV 592
+++ECT NP C G C+N P Y C C+ G++ + ++ C+DIDEC Q LC GRC
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 593 NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKC-ICKPGFVLAP 651
NT+GSF CIC AGF + +G NC+D DEC ++C G C+N G+F+C C G+ +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
Query: 652 NGRYCTDVDECQTPGICMNGHCINSEGSFRC-DCPPGLAVGMDGRVCVDTHMRSTCYGGI 710
GR C D+DEC P C + C+NS GS++C C G G +G+ C+D C +
Sbjct: 668 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDV---DEC---L 718
Query: 711 KKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG---- 766
+ VC + S C + Y + C + + LC +G +G
Sbjct: 719 EPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC 778
Query: 767 ---------------RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
DI+EC +CA+G C N GS++C C+ GY G +C DI
Sbjct: 779 TCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
Query: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCV---NGACRN 868
+ECL ++ +C G C NT GSY CTCP G+ + +TC+DINECE +P + G C N
Sbjct: 838 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECE-HPGLCGPQGECLN 895
Query: 869 NLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAW 928
GSF+C C G +S+ G C D C VN C T G+
Sbjct: 896 TEGSFHCVCQQGFSISADGRTCEDI-----------DEC-VNNTVCDSHGFCDNTAGSF- 942
Query: 929 GSPCERCELDTACPRGL-ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPE--- 984
RC C +G A G C DVNECE+ GVC C N +GSF C C +
Sbjct: 943 -----RC----LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQ 993
Query: 985 ---GLTLDGTGRVCLDIRME---------QCYLKW-DEDECIHPVPGKFRMDACCCAVGA 1031
+T R D+ ++ +CY D C + + CCC GA
Sbjct: 994 EYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGA 1053
Query: 1032 AWGTECE--ECPKPGTKEYETLCPRGAGFANRGDVLT--GRPFYKDINECKAF-PGMCTY 1086
WG CE CP GT E+ +CP+G GF G+ + G YKD +EC F +C
Sbjct: 1054 GWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1113
Query: 1087 GKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
G C NT ++C C G D + C D+DEC+ P C G CVNT GS+ C C
Sbjct: 1114 GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPM 1172
Query: 1147 ESGFMMMKNCM-------DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCV 1199
K C+ I+E + LC + + C PL + + E C
Sbjct: 1173 VLD-ASEKRCIRPAESNEQIEETDVYQDLC----WEHLSDEYVCSRPLVGKQTTYTECCC 1227
Query: 1200 DINE--------CSLSDN-----LCR-----------NGKCVNMIGTYQCSCNPGYQATP 1235
E C L D+ LC V+ Y +P +
Sbjct: 1228 LYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDR 1287
Query: 1236 DRQGCTDI--DECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECE---NN 1290
++ +EC I+NG + +C + Y C C +GY L +C D++EC+ N
Sbjct: 1288 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
Query: 1291 PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
+C +C N G Y+CLC G++ S C +N
Sbjct: 1348 MSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 414 bits (1064), Expect = e-115
Identities = 299/942 (31%), Positives = 406/942 (43%), Gaps = 170/942 (18%)
Query: 852 DINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI-QDSRCE 908
+INEC NP C G C N + C C G + S C+D + T ++ RCE
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 909 VNINGATLKSECCATLGAAWGSPCERCELDTACPRG-LARIKGVTCEDVNECEVFPGVCP 967
N G+ L CP G +A +G C DV+EC + P VC
Sbjct: 608 -NTEGSFL----------------------CICPAGFMASEEGTNCIDVDEC-LRPDVCG 643
Query: 968 NGRCVNSKGSFHCE-CPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACC 1026
G CVN+ G+F CE C G + GR C DI DEC++P D C
Sbjct: 644 EGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDI-----------DECLNPSTCP---DEQC 688
Query: 1027 CAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY 1086
V + +C C + G + + C D++EC P +C
Sbjct: 689 --VNSPGSYQCVPCTE-GFRGWNGQC-------------------LDVDECLE-PNVCAN 725
Query: 1087 GKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
G C N GS+ C C+ G+ + ++C DIDEC+ +LC +G C NT GSF C C +GY
Sbjct: 726 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGY 784
Query: 1147 ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSL 1206
+ C DIDEC+ L C G C NTEGSFQC C G+ S + C DINEC
Sbjct: 785 QLS-AAKDQCEDIDECQHRHL-CAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLE 842
Query: 1207 SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ--CTNSEGSY 1264
++C+ G C+N G+Y C+C G+Q D + C DI+EC G C Q C N+EGS+
Sbjct: 843 DKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECE-HPGLCGPQGECLNTEGSF 900
Query: 1265 ECSCSEGYALMPDGRSCADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMKTC 1323
C C +G+++ DGR+C DIDEC NN +CD G C N G +RCLCY GF A D + C
Sbjct: 901 HCVCQQGFSISADGRTCEDIDECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
Query: 1324 IDVNECDLNSNICMFGECENTKGSFICHC---QLGYSVKKG-----TTGCTDVD------ 1369
+DVNEC+L S +C CEN +GSF+C C YS G T+ DVD
Sbjct: 960 VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKE 1019
Query: 1370 ECEIGAHNCDMHASCLNI--PGSFK--CSCREGWIGNGIKCIDLDECSNGTHQCSINAQC 1425
E + +N + + C N+ P K C C G G G C GT C
Sbjct: 1020 EKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPCPVLGT--AEFTEMC 1076
Query: 1426 VNTPGSYRCACSEGFTGDGFTCSDVDEC-AENINLCENGQCLNVPGAYRCECEMGFTPAS 1484
G S G G D DEC +C+NG CLN Y C C+ G
Sbjct: 1077 PKGKGFVPAGESSSEAG-GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1135
Query: 1485 DSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC---TDIDECADPIN 1541
C D+DEC + C+ G C N G ++C C LD + C + +E + +
Sbjct: 1136 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETD 1195
Query: 1542 CVNGLC-VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVG 1600
LC + Y C+ P +G
Sbjct: 1196 VYQDLCWEHLSDEYVCSRP------------------------------------LVGKQ 1219
Query: 1601 VSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLC---------PGG--------EGFRPNP 1643
+ + CCC G+AWG C CP +S +Y LC P G E + P
Sbjct: 1220 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEA 1279
Query: 1644 ITIILED----------IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI 1693
++D +EC L G C+ G C+ + C+C GY+L C D+
Sbjct: 1280 DPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1338
Query: 1694 DECFA---HPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC 1732
+EC +C C NT G+Y C+C P Y+ + + C
Sbjct: 1339 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
Score = 414 bits (1064), Expect = e-115
Identities = 283/852 (33%), Positives = 384/852 (45%), Gaps = 158/852 (18%)
Query: 1796 GFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS 1855
G+ F K VDIDEC ++ +C+ G C N GSF C CP GF ++ C D+DEC
Sbjct: 578 GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECL 637
Query: 1856 NGDNLCQRNADCINSPGSYRCE-CAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGS 1914
D +C C+N+ G++RCE C +G++++ G C D +ECL P+ C CV+ GS
Sbjct: 638 RPD-VCGEG-HCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGS 694
Query: 1915 YQCI-CHNGFKASQDQTMCMDVDEC-ERHPCGNGTCKNTVGSYNCLCYPGFELTHNND-C 1971
YQC+ C GF+ Q C+DVDEC E + C NG C N GSY C C+ G+ T ++ C
Sbjct: 695 YQCVPCTEGFRGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHC 752
Query: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 2031
DIDEC G +C NG+C N GSF+C C +GY+L+ C D +EC C+ G
Sbjct: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQ 809
Query: 2032 CQNLEGSFRCICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVL 2089
C+N EGSF+C+C GY ++C DINEC ED ++C G C NT G + C CP GF L
Sbjct: 810 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 869
Query: 2090 SDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEV 2149
DN + C D + C P G P C + E
Sbjct: 870 DDN-KTCQDINE-----------CEHP------------------GLCGPQGEC-LNTEG 898
Query: 2150 AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGV 2209
+F +C G ++ + T ED++EC+ + S+G C NT GSFRC C G+ G
Sbjct: 899 SFHCVCQQGF-SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 957
Query: 2210 RCVDTDECSI-GNPCGNGTCTNVIGSFECNC-NEGFEPGPMMN-C--------------- 2251
CVD +EC + CG C NV GSF C C +E E PM C
Sbjct: 958 GCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1017
Query: 2252 -EDINECAQNPLLCAFRCMNTFG----SYECTCPIG--------------YALREDQKMC 2292
E+ EC N L A C N EC C G E +MC
Sbjct: 1018 KEEKKECYYN-LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMC 1076
Query: 2293 ---------------------KDLDECAE-GLHDCESRGMMCKNLIGTFMCICPPGMARR 2330
KD DEC G C++ C N + C C G
Sbjct: 1077 PKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG--FCLNTRPGYECYCKQGTYYD 1134
Query: 2331 PDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL---DNRQGLCF 2387
P C D +EC+ P C +G+CVN GSY C C +S C+ ++ + +
Sbjct: 1135 PVKLQCFDMDECQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1193
Query: 2388 AEVLQTICQMASS-----SRNLVTK----SECCCDGGRGWGHQCELCPLPGTAQYKKIC- 2437
+V Q +C S SR LV K +ECCC G WG QC LCPL + Y ++C
Sbjct: 1194 TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN 1253
Query: 2438 --------PHGPGYTTDGRD-----------------------IDECKVMPNLCTNGQCI 2466
P+G D + +EC ++ N C NG+C+
Sbjct: 1254 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCV 1312
Query: 2467 NTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC----NYICKNTEGSYQCSCPRGYV 2522
+ C C GY D + +C+D++EC + N C NT+GSY+C C GYV
Sbjct: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
Query: 2523 LQEDGKTCKDLD 2534
+ C L+
Sbjct: 1373 PSDKPNYCTPLN 1384
Score = 392 bits (1006), Expect = e-108
Identities = 278/918 (30%), Positives = 388/918 (42%), Gaps = 190/918 (20%)
Query: 1448 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTC 1506
++++EC N ++C G C+N+P Y C C G+ + R C DIDEC+ Q++C G C
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 1507 NNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLN 1565
N G F CIC G+ G NC D+DEC P C G CVNT G + C C +++
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
Query: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
G C D + C ++ S+C P E C VN
Sbjct: 667 QRG-RCED--IDEC---------------------LNPSTC----------PDEQC--VN 690
Query: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
S Y P EGFR + D+DEC E P +C G+C N GS+ C C +GY +
Sbjct: 691 SPGSYQCVPCTEGFRGWNGQCL--DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTP 747
Query: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
D + C DIDEC +C G C NT G++ C C Y C D+ +
Sbjct: 748 DHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE-------- 798
Query: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1805
C++ + +C G+ N T G+ F+ +C G+
Sbjct: 799 ---CQH-------RHLCAH----GQCRN-------TEGS--FQCVCDQ--GYRASGLGDH 833
Query: 1806 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA 1865
DI+EC E +C G CIN GS+ C CP GF +D C+DI+EC + LC
Sbjct: 834 CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEH-PGLCGPQG 891
Query: 1866 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
+C+N+ GS+ C C GF +S +G C D +EC+ SHG C + GS++C+C+ GF+
Sbjct: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
Query: 1925 ASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLC---------YPGFELTHNNDCLD 1973
A QD C+DV+ECE CG C+N GS+ C+C G + + LD
Sbjct: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
Query: 1974 ID---------ECSSFFGQ--VCRNGRCFNEIGSFKCLCNEGY----------------- 2005
+D EC +C N N + +C C G
Sbjct: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPN-VTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
Query: 2006 ---ELTPDGKNCI---------------DTNECVALPGS-CSPGTCQNLEGSFRCICPPG 2046
E+ P GK + D +EC+ C G C N + C C G
Sbjct: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1130
Query: 2047 --YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCF------- 2097
Y+ C D++EC +DP+ C+ G C NT G + C C VL + +RC
Sbjct: 1131 TYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNE 1189
Query: 2098 -----DTRQSFCFTNFENGK-CSVPKAFN-TTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
D Q C+ + + CS P TT +CCC + GE WG C LCP D
Sbjct: 1190 QIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC--LYGEAWGMQCALCPLKDSDD 1247
Query: 2151 FQDLC---------PYGHGTVPSLHD--TRE-----------------DVNECLESPGIC 2182
+ LC PYG + + T E EC G C
Sbjct: 1248 YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-C 1306
Query: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP----CGNGTCTNVIGSFECN 2238
NG+C+ + C+C GY+LD + CVD +EC N C N C N GS++C
Sbjct: 1307 ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1366
Query: 2239 CNEGFEPGPMMN-CEDIN 2255
C G+ P N C +N
Sbjct: 1367 CLPGYVPSDKPNYCTPLN 1384
Score = 371 bits (952), Expect = e-102
Identities = 261/851 (30%), Positives = 363/851 (42%), Gaps = 183/851 (21%)
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCT 2073
+ NEC P C G C NL + CIC GY + C+DI+EC + ++C G C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 2074 NTPGGFQCLCPPGFVLSDNGRRCFDT---------------------RQSFCFTNF---E 2109
NT G F C+CP GF+ S+ G C D R +C + + +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
Query: 2110 NGKC-SVPKAFN-TTKAKCCCSKMPG-----------EGWGDPC---------ELCPKDD 2147
G+C + + N +T C PG GW C +C D
Sbjct: 668 RGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 727
Query: 2148 ----EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYN 2203
E ++ C G+ P H D++EC + +C NGQC NT+GSFRC C GY
Sbjct: 728 CSNLEGSYMCSCHKGYTRTPD-HKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQ 785
Query: 2204 LDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPL 2262
L +C D DEC + C +G C N GSF+C C++G+ G +CEDINEC ++
Sbjct: 786 LSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS 845
Query: 2263 LC-AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFM 2320
+C C+NT GSY+CTCP G+ L +D K C+D++EC GL C +G C N G+F
Sbjct: 846 VCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPGL--CGPQG-ECLNTEGSFH 901
Query: 2321 CICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLD 2380
C+C G + DG C D +EC +G C N GS+RC C +GFQ+ G C+D
Sbjct: 902 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
Query: 2381 NRQ-----GLC---FAEVLQ----TICQMASSSRNLVT---------------------K 2407
+ G+C F E ++ +C + + +T K
Sbjct: 962 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
Query: 2408 SEC-----------------------CCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPG 2442
EC CC G GWG CE+ CP+ GTA++ ++CP G G
Sbjct: 1022 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1081
Query: 2443 YTTDG-----------RDIDECKVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2490
+ G +D DEC + +C NG C+NT + C+CK G D C
Sbjct: 1082 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
Query: 2491 DLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTC-------KDLDECQTKQHN 2542
D+DEC Q P C + C NTEGSY C C VL K C + ++E Q
Sbjct: 1142 DMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDL 1200
Query: 2543 C------QFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKG------ICQN 2590
C +++C L G T C+ G Q +LC K +C N
Sbjct: 1201 CWEHLSDEYVCSRPLVG------KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-N 1253
Query: 2591 TP-----------------GSFSCECQRGFSLDATGLNCEDV--DECDGNHRCQHG-CQN 2630
P ++ E F D + E++ +EC + C++G C
Sbjct: 1254 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVR 1313
Query: 2631 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPN----ACGSASCYNTLGSYKCACPSGFSF 2686
+ GY C C GY CVD NEC N C +A C NT GSYKC C G+
Sbjct: 1314 VQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVP 1373
Query: 2687 DQFSSACHDVN 2697
+ C +N
Sbjct: 1374 SDKPNYCTPLN 1384
Score = 364 bits (935), Expect = e-100
Identities = 253/793 (31%), Positives = 350/793 (44%), Gaps = 153/793 (19%)
Query: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDEC-TSNPCTNGDCVNT 552
ID C +LC GRC T S+ C C G+ G +CIDVDEC + C G CVNT
Sbjct: 591 IDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNT 650
Query: 553 PGSYYCK-CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCI-CNAGFELTT 610
G++ C+ C +G++ T + C DIDEC+ N C + +CVN+ GS+QC+ C GF
Sbjct: 651 VGAFRCEYCDSGYRMT-QRGRCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFR--- 705
Query: 611 DGKN--CVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGIC 668
G N C+D DEC N+C NG C N +GS+ C C G+ P+ ++C D+DECQ +C
Sbjct: 706 -GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC 764
Query: 669 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVD----THMRSTCYG------GIKKGVCVRP 718
+NG C N+EGSFRC C G + C D H +G G + VC +
Sbjct: 765 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG 824
Query: 719 FPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG----RDINECAL 774
+ + C N CQ N+A + C+ G +D +DINEC
Sbjct: 825 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD-CTCPDGFQLDDNKTCQDINECE- 882
Query: 775 DPDICA-NGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD-NGLCRNTPGS 832
P +C G C N GS+ C C G+ A GR C DIDEC VN +CD +G C NT GS
Sbjct: 883 HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGS 941
Query: 833 YSCTCPPGYVFRTETETCEDINECE--SNPCVNGACRNNLGSFNCECSPGSK-------- 882
+ C C G+ + + C D+NECE S C C N GSF C C+ ++
Sbjct: 942 FRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQ 1001
Query: 883 ---LSSTGL-ICID---SLKGTCWLNIQD-SRCEVNINGATLKSECCATLGAAWGSPCE- 933
+ST L + +D K C+ N+ D S C+ + K ECC T GA WG CE
Sbjct: 1002 CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEI 1061
Query: 934 -------RCELDTACPRGLARIK---------GVTCEDVNECEVF--------------- 962
E CP+G + G +D +EC +F
Sbjct: 1062 FPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRP 1121
Query: 963 ---------------------------PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
P C +G+CVN++GS++C C + LD + + C
Sbjct: 1122 GYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1181
Query: 996 L------------DIRMEQCYLKW-DEDECIHPVPGK-FRMDACCCAVGAAWGTECEECP 1041
+ D+ + C+ DE C P+ GK CCC G AWG +C CP
Sbjct: 1182 IRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCP 1241
Query: 1042 KPGTKEYETLC---------PRG----AGFANRGDVLTGRPFYKD----------INECK 1078
+ +Y LC P G F+ + F +D EC
Sbjct: 1242 LKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG 1301
Query: 1079 AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDEC-----RISPDLCGSGICVN 1133
G C G+C + C C G+ LD + C D++EC R+S LC + C+N
Sbjct: 1302 ILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS--LCKNAKCIN 1358
Query: 1134 TPGSFECECFEGY 1146
T GS++C C GY
Sbjct: 1359 TDGSYKCLCLPGY 1371
Score = 363 bits (933), Expect = 1e-99
Identities = 252/812 (31%), Positives = 364/812 (44%), Gaps = 113/812 (13%)
Query: 503 NLCLNGRCIPTVSSYRCE-CNMGYKQDANGDCIDVDECTS-NPCTNGDCVNTPGSYYC-K 559
++C G C+ TV ++RCE C+ GY+ G C D+DEC + + C + CVN+PGSY C
Sbjct: 640 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP 699
Query: 560 CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHD 619
C GF+ + C+D+DEC++ V C NG C N +GS+ C C+ G+ T D K+C D D
Sbjct: 700 CTEGFRGWNGQ--CLDVDECLEPNV-CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 756
Query: 620 ECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGS 679
EC N+C+NG C N +GSF+C C G+ L+ C D+DECQ +C +G C N+EGS
Sbjct: 757 ECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGS 816
Query: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGE 739
F+C C G G C D + ++G C+ T C PD GF
Sbjct: 817 FQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN------TAGSYDCTCPD-GF-- 867
Query: 740 PCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSG 798
+ + C +DINEC P +C G C N GS+ C C G
Sbjct: 868 ---------QLDDNKTC----------QDINECE-HPGLCGPQGECLNTEGSFHCVCQQG 907
Query: 799 YEPDASGRNCIDIDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECE 857
+ A GR C DIDEC VN +CD+ G C NT GS+ C C G+ + + C D+NECE
Sbjct: 908 FSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECE 966
Query: 858 --SNPCVNGACRNNLGSFNCECSPGSK-----------LSSTGL-ICIDSLKGT---CWL 900
S C C N GSF C C+ ++ +ST L + +D K C+
Sbjct: 967 LLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY 1026
Query: 901 NIQD-SRCEVNINGATLKSECCATLGAAWGSPCE--------RCELDTACPRGLARIK-- 949
N+ D S C+ + K ECC T GA WG CE E CP+G +
Sbjct: 1027 NLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAG 1086
Query: 950 -------GVTCEDVNECEVF-PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
G +D +EC +F +C NG C+N++ + C C +G D C D M+
Sbjct: 1087 ESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFD--MD 1144
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR 1061
+C D CI D C ++ C E + P A
Sbjct: 1145 ECQ---DPSSCI---------DGQCVNTEGSYNCFCTHPMVLDASEKRCIRP-----AES 1187
Query: 1062 GDVLTGRPFYKDIN-ECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCT--DIDE 1118
+ + Y+D+ E + +C+ +C C G A M+ C D D+
Sbjct: 1188 NEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDD 1247
Query: 1119 ----CRISP----DLCGSGICVNTPGSFECECFEGY-ESGFMMMKNCMDIDECERNPLL- 1168
C I G V+ + E + + F+ + +EC +L
Sbjct: 1248 YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG---ILN 1304
Query: 1169 -CRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDN---LCRNGKCVNMIGTYQ 1224
C G CV + + CDC G+ L ++ CVD+NEC +N LC+N KC+N G+Y+
Sbjct: 1305 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
C C PGY + CT ++ + + D +
Sbjct: 1365 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE 1396
Score = 362 bits (930), Expect = 2e-99
Identities = 249/824 (30%), Positives = 346/824 (41%), Gaps = 134/824 (16%)
Query: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 335
+++EC P IC G+CIN + C C G++ SE +KC DIDEC+ + +C G C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 336 NTVGSYFCVCPRGYVTSTDGSRCIDQRT---------GMCFSGLVNGRCAQELPG-RMTK 385
NT GS+ C+CP G++ S +G+ CID G C + + RC G RMT+
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
Query: 386 MQCCCEPGRCWGIGTIPEACPVRGSEEYRRL-CMDGLP--MGGIPGSAGSRPGGTGGNGF 442
C + C T P+ V Y+ + C +G G NG
Sbjct: 668 RGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 727
Query: 443 APSGNGNGYGPGGTGFIPIPGG----------------NGFSPGVGGAGVGAGGQGPIIT 486
+ G+ G+ P NG G+ GQG ++
Sbjct: 728 CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLS 787
Query: 487 GLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSNP-- 543
+ ID C+H +LC +G+C T S++C C+ GY+ GD C D++EC +
Sbjct: 788 AAKDQCEDIDECQHR-HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 846
Query: 544 CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICN 603
C GDC+NT GSY C C GFQ K C DI+EC G+ G C+NT+GSF C+C
Sbjct: 847 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGPQGECLNTEGSFHCVCQ 905
Query: 604 AGFELTTDGKNCVDHDECTTTNMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC 662
GF ++ DG+ C D DEC +C +G C N GSF+C+C GF +G+ C DV+EC
Sbjct: 906 QGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC 965
Query: 663 Q-TPGICMNGHCINSEGSFRC--------------DCPPGLAVGMDGRVCVDTHMRSTCY 707
+ G+C C N EGSF C C + +D V + CY
Sbjct: 966 ELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECY 1025
Query: 708 GGIK-KGVCVRPFPGAVTKSECCCANPDYGFGEPCQ--PCPAKNSAEFHGLCSSGVGITV 764
+ +C VTK ECCC + G+G+ C+ PCP +AEF +C G G
Sbjct: 1026 YNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVP 1084
Query: 765 DG-----------RDINECAL-DPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 812
G +D +EC L +IC NG C N R Y C C G D C D+D
Sbjct: 1085 AGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMD 1144
Query: 813 ECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGS 872
EC + C +G C NT GSY+C C V + C I ESN +
Sbjct: 1145 EC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC--IRPAESNEQIEET------- 1194
Query: 873 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSR-CEVNING-ATLKSECCATLGAAWGS 930
D + CW ++ D C + G T +ECC G AWG
Sbjct: 1195 -------------------DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGM 1235
Query: 931 PCERCELDTA------C---------PRGLARIKGVTCE--------------------- 954
C C L + C P G + + +
Sbjct: 1236 QCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL 1295
Query: 955 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 998
EC + G C NGRCV + + C+C +G LD C+D+
Sbjct: 1296 QAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1338
Score = 349 bits (895), Expect = 3e-95
Identities = 270/920 (29%), Positives = 388/920 (42%), Gaps = 146/920 (15%)
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPD 802
P P + + E +S V +INEC ++PDIC G C NL Y C C GY
Sbjct: 523 PVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFS 582
Query: 803 ASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPC 861
R C+DIDEC + LC G C NT GS+ C CP G++ E C D++EC + C
Sbjct: 583 EQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVC 642
Query: 862 VNGACRNNLGSFNCE-CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCE---VNINGATLK 917
G C N +G+F CE C G +++ G RCE +N +T
Sbjct: 643 GEGHCVNTVGAFRCEYCDSGYRMTQRG------------------RCEDIDECLNPSTCP 684
Query: 918 SECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGS 977
E C ++ +C C G G C DV+EC + P VC NG C N +GS
Sbjct: 685 DEQCVNSPGSY-----QC---VPCTEGFRGWNG-QCLDVDEC-LEPNVCANGDCSNLEGS 734
Query: 978 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 1037
+ C C +G T + C DI DEC C G TE
Sbjct: 735 YMCSCHKGYTRTPDHKHCRDI-----------DEC---------QQGNLCVNGQCKNTE- 773
Query: 1038 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFK 1097
+ C +G + D +DI+EC+ +C +G+CRNT GSF+
Sbjct: 774 --------GSFRCTCGQGYQLSAAKDQC------EDIDECQ-HRHLCAHGQCRNTEGSFQ 818
Query: 1098 CRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM 1157
C C+ G+ +C DI+EC +C G C+NT GS++C C +G++ K C
Sbjct: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--LDDNKTCQ 876
Query: 1158 DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC-RNGKC 1216
DI+ECE L G C+NTEGSF C C G +S C DI+EC +++ +C +G C
Sbjct: 877 DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFC 935
Query: 1217 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC-DTQCTNSEGSYECSC---SEGY 1272
N G+++C C G+QA D QGC D++EC +++G C + C N EGS+ C C ++ Y
Sbjct: 936 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEY 995
Query: 1273 ALMPD---GRSCADID-----------ECE---NNPDICDGGQCTNIPGEYRCLCYDGFM 1315
+ M R+ D+D EC N+ +CD N+ + C C G
Sbjct: 996 SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT-KQECCCTSG-- 1052
Query: 1316 ASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGA 1375
++ C + C KG F+ + S + G D DEC +
Sbjct: 1053 --AGWGDNCEIFPCPVLGTAEFTEMCPKGKG-FVPAGE--SSSEAGGENYKDADECLLFG 1107
Query: 1376 HNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ CLN ++C C++G + +K C D+DEC + + I+ QCVNT GSY
Sbjct: 1108 QEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS--SCIDGQCVNTEGSYN 1165
Query: 1434 CACSEGFTGDG--------------FTCSDV--DECAENIN---LCENGQCLNVPGAYRC 1474
C C+ D +DV D C E+++ +C C
Sbjct: 1166 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1225
Query: 1475 ECEMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLPGMFHCICD---------DGYEL- 1523
C G C D + +C + T P + D D Y +
Sbjct: 1226 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
Query: 1524 DRTGGNCTDI--DECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD-------- 1573
DR + ++ +EC C NG CV Y C+C + L+ + CVD
Sbjct: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1345
Query: 1574 NRVGNCYLKFGPRGDGSLSC 1593
NR+ C DGS C
Sbjct: 1346 NRMSLCKNAKCINTDGSYKC 1365
Score = 320 bits (821), Expect = 1e-86
Identities = 190/521 (36%), Positives = 244/521 (46%), Gaps = 52/521 (9%)
Query: 2253 DINECAQNPLLC-AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM 2311
+INEC NP +C A C+N Y C C GY E Q+ C D+DEC + H C S+G
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGR- 605
Query: 2312 CKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCE-CNEGFQ 2370
C+N G+F+CICP G +G C+D +EC +P +C G CVN +G++RCE C+ G++
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
Query: 2371 SSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGT 2430
+ G C D + L + C + S V C +G RGW QC
Sbjct: 665 MTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVP----CTEGFRGWNGQC-------- 711
Query: 2431 AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2490
D+DEC + PN+C NG C N GS+ C C GYT C
Sbjct: 712 -----------------LDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
Query: 2491 DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 2550
D+DEC Q N CKNTEGS++C+C +GY L C+D+DECQ + C NT
Sbjct: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 813
Query: 2551 LGGFTCKCPPGFTQHHTA--CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT 2608
G F C C G+ C D NEC S+C +G C NT GS+ C C GF LD
Sbjct: 814 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLD-D 871
Query: 2609 GLNCEDVDECDGNHRC--QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS 2666
C+D++EC+ C Q C N G + C C QG+ C D +EC N C S
Sbjct: 872 NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDS 931
Query: 2667 -ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPP- 2723
C NT GS++C C GF Q C DVNEC C C N EG +LC C
Sbjct: 932 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 991
Query: 2724 -GYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACY 2763
Y G C S LD +VD+ E Y
Sbjct: 992 NQEYSPMTGQCRSRTS------TDLDVDVDQPKEEKKECYY 1026
Score = 218 bits (554), Expect = 9e-56
Identities = 111/326 (34%), Positives = 155/326 (47%), Gaps = 47/326 (14%)
Query: 2445 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY 2504
T +I+EC V P++C G CIN + C C GY C+D+DEC+Q C+
Sbjct: 544 TQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ 603
Query: 2505 -ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK------ 2557
C+NTEGS+ C CP G++ E+G C D+DEC + CVNT+G F C+
Sbjct: 604 GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 663
Query: 2558 ------------------------------------CPPGFTQHHTACIDNNECGSQPSL 2581
C GF + C+D +EC +P++
Sbjct: 664 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNV 722
Query: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG-CQNILGGYRCGCP 2640
C A G C N GS+ C C +G++ +C D+DEC + C +G C+N G +RC C
Sbjct: 723 C-ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 781
Query: 2641 QGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECS 2700
QGY +QC D +EC + + C C NT GS++C C G+ C D+NEC
Sbjct: 782 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL 841
Query: 2701 SSKNPCNYG-CSNTEGGYLCGCPPGY 2725
K+ C G C NT G Y C CP G+
Sbjct: 842 EDKSVCQRGDCINTAGSYDCTCPDGF 867
Score = 209 bits (533), Expect = 2e-53
Identities = 217/841 (25%), Positives = 301/841 (35%), Gaps = 202/841 (24%)
Query: 124 CSRPNMCTCSSGQISSTCGSKSIQQCSV--------------RCMNGGTCADDHCQCQKG 169
C RP++C G +T G+ + C C+N TC D+ C G
Sbjct: 636 CLRPDVC--GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPG 693
Query: 170 YIGTYCGQPVCE-----NG-CQNGGRCIGPNRCA---C--VYGFTGPQCERDYRTGPCFT 218
+Y P E NG C + C+ PN CA C + G C + Y P
Sbjct: 694 ---SYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHK 750
Query: 219 QVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDV 277
+ CQ G +C C T G C C +G+ + C+D+
Sbjct: 751 HCRDIDECQ---QGNLCVNGQCKNTEG---SFRCT--------CGQGYQLSAAKDQCEDI 796
Query: 278 DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNT 337
DECQ +C G C NT GSF+C C G++ S CEDI+EC +C+ G+C NT
Sbjct: 797 DECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 855
Query: 338 VGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
GSY C CP G+ D C D + G+C G C C C+ G
Sbjct: 856 AGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGP---QGECL----NTEGSFHCVCQQG 907
Query: 394 --------RCWGIGTIPE--ACPVRG-----SEEYRRLCMDGLP-----MGGIPGSAGSR 433
C I C G + +R LC G G + +
Sbjct: 908 FSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECEL 967
Query: 434 PGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNG--FSPGVGGAGVGAGGQGPIITGLTIL 491
G G F + G+ F+ + +SP G T L
Sbjct: 968 LSGVCGEAFCENVEGS--------FLCVCADENQEYSPMTGQCRSRTS---------TDL 1010
Query: 492 NQTIDICKHHANLC---LNGRCI------PTVSSYRCECNMGYKQDANGDCIDVDECTSN 542
+ +D K C LN + P V+ C C G D C
Sbjct: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWG--------DNCEIF 1062
Query: 543 PCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI--------DIDECIQNG-VLCKNGRCVN 593
PC V + C G P ++ D DEC+ G +CKNG C+N
Sbjct: 1063 PCP----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN 1118
Query: 594 TDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNG 653
T ++C C G C D DEC + C++G C+N +GS+ C C VL +
Sbjct: 1119 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE 1178
Query: 654 RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG 713
+ C E + I ++ C L+ +
Sbjct: 1179 KRCIRPAE--------SNEQIEETDVYQDLCWEHLS---------------------DEY 1209
Query: 714 VCVRPFPG-AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR----- 767
VC RP G T +ECCC + +G C CP K+S ++ LC+ I V GR
Sbjct: 1210 VCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCN----IPVTGRRQPYG 1264
Query: 768 -------------------------------DINECALDPDICANGICENLRGSYRCNCN 796
EC + + C NG C ++ Y C+C
Sbjct: 1265 RDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCF 1323
Query: 797 SGYEPDASGRNCIDIDEC--LVNRL-LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDI 853
GY D + C+D++EC L NR+ LC N C NT GSY C C PGYV + C +
Sbjct: 1324 DGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPL 1383
Query: 854 N 854
N
Sbjct: 1384 N 1384
Score = 159 bits (402), Expect = 4e-38
Identities = 178/745 (23%), Positives = 257/745 (34%), Gaps = 167/745 (22%)
Query: 62 EYREEGAAVASRVRRRGQQDVLRGPNVC---------GSRFHSYCCPGWKTLPGG----N 108
EY + G + R R + L P+ C GS C G++ G +
Sbjct: 657 EYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVD 715
Query: 109 QCIVPICRNSCGDGFCSRPN---MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQ 165
+C+ P N C +G CS MC+C G + T K + C G C + C+
Sbjct: 716 ECLEP---NVCANGDCSNLEGSYMCSCHKGY-TRTPDHKHCRDID-ECQQGNLCVNGQCK 770
Query: 166 CQKGYIGTYCGQPV--------CEN--GCQNGGRCI--------GPNRCACVYGFT---- 203
+G CGQ CE+ CQ+ C G +C C G+
Sbjct: 771 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 830
Query: 204 GPQCE---------RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMC 254
G CE + G C + C G C I HP +C
Sbjct: 831 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQDINEC-EHP-GLC 887
Query: 255 PAQPQ----------PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCP 304
Q + C++GF + C+D+DEC G C NT GSF C C
Sbjct: 888 GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCY 947
Query: 305 AGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP---RGYV---------TS 352
G + + Q C D++EC ++ G+C C N GS+ CVC + Y TS
Sbjct: 948 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTS 1007
Query: 353 TDGSRCIDQ---RTGMCFSGLVNGR-CAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVR 408
TD +DQ C+ L + C L +TK +CCC G WG CPV
Sbjct: 1008 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVL 1067
Query: 409 GSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFS 468
G+ E+ +C P G GF+P
Sbjct: 1068 GTAEFTEMC-----------------------------------PKGKGFVP-------- 1084
Query: 469 PGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMG-YKQ 527
G + AGG+ + +C NG C+ T Y C C G Y
Sbjct: 1085 --AGESSSEAGGEN--------YKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1134
Query: 528 DANGDCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI---DIDECIQNG 583
C D+DEC + C +G CVNT GSY C C +++ CI + +E I+
Sbjct: 1135 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET 1194
Query: 584 VLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCIC 643
+ ++ + + C + TT + C + E L + ++D + C
Sbjct: 1195 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
Query: 644 KPGFVLAPNGR---------YCTDVD------------------ECQTPGICMNGHCINS 676
P GR Y + D EC C NG C+
Sbjct: 1255 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV 1314
Query: 677 EGSFRCDCPPGLAVGMDGRVCVDTH 701
+ + CDC G + CVD +
Sbjct: 1315 QEGYTCDCFDGYHLDTAKMTCVDVN 1339
Score = 152 bits (383), Expect = 6e-36
Identities = 144/559 (25%), Positives = 204/559 (36%), Gaps = 119/559 (21%)
Query: 86 PNVCGSR---------FHSYCCPGWKTLPGGNQCI-VPICRNSCGDGFCSRPNMCTCSSG 135
P +CG + FH C G+ G C + C N+ C C ++G
Sbjct: 884 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT---VCDSHGFCDNTAG 940
Query: 136 QISSTCGSKSIQQCSVRCMNGGTCAD-DHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPN 194
C Q +G C D + C+ G CG+ CEN + C+ +
Sbjct: 941 SFRCLC-----YQGFQAPQDGQGCVDVNECELLSGV----CGEAFCEN-VEGSFLCVCAD 990
Query: 195 RCACVYGFTGPQCERDYRTG-------------PCFTQVNN-QMCQGQLTGIVCTKTLCC 240
TG QC T C+ +N+ +C L V TK CC
Sbjct: 991 ENQEYSPMTG-QCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV-TKQECC 1048
Query: 241 ATIGRAWGHPCEMCPA---------QPQPCRRGFIPNIRTGA------CQDVDECQAI-P 284
T G WG CE+ P + P +GF+P + + +D DEC
Sbjct: 1049 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1108
Query: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
IC+ G C+NT +EC C G +C D+DEC P C G+C NT GSY C
Sbjct: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCF 1167
Query: 345 CPRGYVTSTDGSRCI------------DQRTGMCFSGLVNGR-CAQELPGRMTK-MQCCC 390
C V RCI D +C+ L + C++ L G+ T +CCC
Sbjct: 1168 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC 1227
Query: 391 EPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNG 450
G WG+ CP++ S++Y +LC IP + +P G A
Sbjct: 1228 LYGEAWGMQC--ALCPLKDSDDYAQLC-------NIPVTGRRQPYGRD----ALVDFSEQ 1274
Query: 451 YGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANL---CLN 507
Y P P LN ++ + C N
Sbjct: 1275 YTPEA--------------------------DPYFIQDRFLNSFEELQAEECGILNGCEN 1308
Query: 508 GRCIPTVSSYRCECNMGYKQD-ANGDCIDVDECTS-----NPCTNGDCVNTPGSYYCKCH 561
GRC+ Y C+C GY D A C+DV+EC + C N C+NT GSY C C
Sbjct: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
Query: 562 AGFQRTPTKQACIDIDECI 580
G+ + C ++ +
Sbjct: 1369 PGYVPSDKPNYCTPLNTAL 1387
Score = 132 bits (333), Expect = 4e-30
Identities = 69/202 (34%), Positives = 103/202 (50%), Gaps = 19/202 (9%)
Query: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWG-SPCERCELDTA---------CPRGL 945
G C+ S+C + G + + +CC T+G +WG + C++C + C G
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
Query: 946 ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD----IRME 1001
R+ C+D+NEC++ GVCPNG C+N+ GS+ C C G D T C+ I E
Sbjct: 291 KRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEE 349
Query: 1002 Q--CY-LKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
+ CY L +C+HP+ CCC+VG AWG CE+CP PGT ++ +CP G G+
Sbjct: 350 KGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409
Query: 1059 ANRGDVLTGRPFYKDINECKAF 1080
G V RP + + + F
Sbjct: 410 TVSG-VHRRRPIHHHVGKGPVF 430
Score = 108 bits (269), Expect = 1e-22
Identities = 57/134 (42%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 2320 MCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC- 2378
M C PG +R + C D NEC+ + G+C NG C+N +GSYRC C GF + + C
Sbjct: 283 MMECLPGY-KRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Query: 2379 -----LDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 2433
+ +G C+ V M S +L TK CCC G+ WG CE CPLPGTA +
Sbjct: 341 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHL-TKQLCCCSVGKAWGPHCEKCPLPGTAAF 399
Query: 2434 KKICPHGPGYTTDG 2447
K+ICP G GYT G
Sbjct: 400 KEICPGGMGYTVSG 413
Score = 101 bits (252), Expect = 9e-21
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 49/202 (24%)
Query: 1603 RSSCCCSLGKAWG-NPCETCPPVNSTEYYT----LCPGGEGFRPNPITIILEDIDECQEL 1657
+ CC ++G +WG N C+ CP S Y PG + R N +DI+ECQ L
Sbjct: 252 QEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK--RVN--NTFCQDINECQ-L 306
Query: 1658 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTC 1717
G+C G C+NT GS++C C G+ GP ++ +C
Sbjct: 307 QGVCPNGECLNTMGSYRCTCKIGF----------------------GPDPTFS-----SC 339
Query: 1718 ICPPEYMQVNGGHNCMDMRKSFCYRSY-NGTTCENELPFNVTKRMCCCTYNVGKAWNKPC 1776
+ P + G CYR +G C + L ++TK++CCC +VGKAW C
Sbjct: 340 VPDPPVISEEKGP---------CYRLVSSGRQCMHPLSVHLTKQLCCC--SVGKAWGPHC 388
Query: 1777 EPCPTPGTADFKTICGNIPGFT 1798
E CP PGTA FK IC G+T
Sbjct: 389 EKCPLPGTAAFKEICPGGMGYT 410
Score = 96.3 bits (238), Expect = 4e-19
Identities = 58/218 (26%), Positives = 87/218 (39%), Gaps = 51/218 (23%)
Query: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQ--------PCRRG 264
G CF + C L G+ + CC T+G +WG + C+ CP +P C G
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG 289
Query: 265 FIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSI 324
+ + CQD++ECQ + G+C G C+NT+GS+ C C G T C
Sbjct: 290 Y-KRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC-------- 339
Query: 325 IPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGR-CAQELPGRM 383
I + G C+ + +GR C L +
Sbjct: 340 ----------------------------VPDPPVISEEKGPCYRLVSSGRQCMHPLSVHL 371
Query: 384 TKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGL 421
TK CCC G+ WG E CP+ G+ ++ +C G+
Sbjct: 372 TKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGM 407
Score = 90.1 bits (222), Expect = 3e-17
Identities = 45/130 (34%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 643 CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--- 699
C PG+ N +C D++ECQ G+C NG C+N+ GS+RC C G CV
Sbjct: 286 CLPGYKRV-NNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 700 --THMRSTCYGGIKKG-VCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC 756
+ + CY + G C+ P +TK CCC + +G C+ CP +A F +C
Sbjct: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCC-SVGKAWGPHCEKCPLPGTAAFKEIC 403
Query: 757 SSGVGITVDG 766
G+G TV G
Sbjct: 404 PGGMGYTVSG 413
Score = 86.7 bits (213), Expect = 3e-16
Identities = 67/200 (33%), Positives = 88/200 (44%), Gaps = 30/200 (15%)
Query: 1988 GRCFNE-IGSFKCLCNEGYELTPDGKNCIDT-------NECVALPGSCS-PGTCQNLEGS 2038
GRCF E IGS C + ++C T N+C P S G Q +E
Sbjct: 231 GRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME-- 285
Query: 2039 FRCICPPGYE-VKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC- 2096
C PGY+ V + C DINEC +C G C NT G ++C C GF C
Sbjct: 286 ----CLPGYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Query: 2097 -----FDTRQSFCFTNFENGK-CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
+ C+ +G+ C P + + TK CCCS G+ WG CE CP A
Sbjct: 341 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV--GKAWGPHCEKCPLPGTAA 398
Query: 2151 FQDLCPYGHG-TVPSLHDTR 2169
F+++CP G G TV +H R
Sbjct: 399 FKEICPGGMGYTVSGVHRRR 418
Score = 86.3 bits (212), Expect = 4e-16
Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDN------RVGNCYLKF 1583
C DI+EC C NG C+NT G Y C C F +PT CV + G CY
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357
Query: 1584 GPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
C + V +++ CCCS+GKAWG CE CP + + +CPGG G+
Sbjct: 358 S----SGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409
Score = 80.1 bits (196), Expect = 3e-14
Identities = 46/126 (36%), Positives = 69/126 (54%), Gaps = 10/126 (7%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPL-PGTAQYKKICPHGP 2441
G CF E + + C A L + +CC G WG ++C+ CP P Y ++ P
Sbjct: 231 GRCFQETIGSQCGKALPG--LSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 2442 GY----TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI-DLDECS 2496
GY T +DI+EC++ +C NG+C+NTMGS+RC CK+G+ D + +SC+ D S
Sbjct: 289 GYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
Query: 2497 QSPKPC 2502
+ PC
Sbjct: 348 EEKGPC 353
Score = 75.5 bits (184), Expect = 7e-13
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 945 LARIKGVTCEDVNECEVFPG---VCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
++RI G T + E + PG V G V + H + V ++
Sbjct: 174 VSRIDGPTGQKTKEAQ--PGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG 231
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWG-TECEECPK-PGTKEYETLCPRGAGFA 1059
+C+ + +C +PG + + CC VG +WG +C++CPK P Y + G+
Sbjct: 232 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK 291
Query: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 1113
F +DINEC+ G+C G+C NT+GS++C C GF D +C
Sbjct: 292 R-----VNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 64.3 bits (155), Expect = 2e-09
Identities = 62/239 (25%), Positives = 83/239 (34%), Gaps = 81/239 (33%)
Query: 715 CVRPFPGAVTKSECC-CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECA 773
C + PG + +CC +GF + CQ CP K S +HG
Sbjct: 242 CGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPS--YHGY------------------ 280
Query: 774 LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSY 833
N + E L G R N C DI+EC + + C NG C NT GSY
Sbjct: 281 -------NQMMECLPGYKRVN----------NTFCQDINECQLQGV-CPNGECLNTMGSY 322
Query: 834 SCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDS 893
CTC G+ + C +P V I
Sbjct: 323 RCTCKIGF------GPDPTFSSCVPDPPV----------------------------ISE 348
Query: 894 LKGTCWLNIQDSR-CEVNINGATLKSECCATLGAAWGSPCERCEL------DTACPRGL 945
KG C+ + R C ++ K CC ++G AWG CE+C L CP G+
Sbjct: 349 EKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGM 407
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 1740 CYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPT-PGTADFKTICGNIPGFT 1798
C++ G+ C LP + CC T +NK C+ CP P + + +PG+
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPSYHGYNQMMECLPGYK 291
Query: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC 1848
++ DI+EC ++ G+C NG C+N +GS+RC C GF + C
Sbjct: 292 -RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 60.8 bits (146), Expect = 2e-08
Identities = 52/201 (25%), Positives = 74/201 (36%), Gaps = 54/201 (26%)
Query: 520 ECNMGYKQDANGDCIDVDECT-SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDE 578
EC GYK+ N C D++EC C NG+C+NT GSY C C GF PT +C+
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 579 CIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS 638
I + G C + L + G+ C+ T
Sbjct: 345 VISE----EKGPC--------------YRLVSSGRQCMHPLSVHLTKQL----------- 375
Query: 639 FKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV 698
C C G P+ ++C PG +F+ CP G+ + G
Sbjct: 376 --CCCSVGKAWGPH------CEKCPLPG----------TAAFKEICPGGMGYTVSG---- 413
Query: 699 DTHMRSTCYGGIKKG-VCVRP 718
H R + + KG V V+P
Sbjct: 414 -VHRRRPIHHHVGKGPVFVKP 433
Score = 58.9 bits (141), Expect = 7e-08
Identities = 49/168 (29%), Positives = 69/168 (41%), Gaps = 28/168 (16%)
Query: 109 QCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQK 168
+C + CG C G + ++ G Q+C + G + +C
Sbjct: 232 RCFQETIGSQCGKALPGLSKQEDCC-GTVGTSWGFNKCQKCPKKPSYHGY--NQMMECLP 288
Query: 169 GYI---GTYCG-------QPVCENG-CQNGGRCIGPNRCACVYGF----TGPQCERD--- 210
GY T+C Q VC NG C N +G RC C GF T C D
Sbjct: 289 GYKRVNNTFCQDINECQLQGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 211 --YRTGPCFTQVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
GPC+ V++ + C L+ + TK LCC ++G+AWG CE CP
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 392
Score = 52.8 bits (125), Expect = 5e-06
Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 2652 CVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD-QFSSACHDVNECSSSKNPC 2706
C D NEC C + C NT+GSY+C C GF D FSS D S K PC
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
Score = 51.6 bits (122), Expect = 1e-05
Identities = 63/245 (25%), Positives = 86/245 (35%), Gaps = 69/245 (28%)
Query: 2099 TRQSFCFTNFENGKCSVPKAF-NTTKAKCCCSKMPGEGWG-DPCELCPKDDEVAFQDLCP 2156
T+ CF +C KA +K + CC + G WG + C+ CPK
Sbjct: 228 TQLGRCFQETIGSQCG--KALPGLSKQEDCCGTV-GTSWGFNKCQKCPKK---------- 274
Query: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
PS H + + EC GY C D +E
Sbjct: 275 ------PSYHGYNQMM------------------------ECLPGYKR-VNNTFCQDINE 303
Query: 2217 CSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR---CMNTFG 2273
C + C NG C N +GS+ C C GF P P + C +P + + C
Sbjct: 304 CQLQGVCPNGECLNTMGSYRCTCKIGFGPDP-----TFSSCVPDPPVISEEKGPCYRLVS 358
Query: 2274 S-YECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKN--LIGT--FMCICPPGMA 2328
S +C P+ L K L C+ G ++ G C+ L GT F ICP GM
Sbjct: 359 SGRQCMHPLSVHL------TKQLCCCSVG----KAWGPHCEKCPLPGTAAFKEICPGGMG 408
Query: 2329 RRPDG 2333
G
Sbjct: 409 YTVSG 413
Score = 51.6 bits (122), Expect = 1e-05
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 1857 GDNLCQRNADCINSPGSY----RCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
G N CQ+ C P + EC G+K N C D NEC ++ VC +G C++
Sbjct: 264 GFNKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTM 319
Query: 1913 GSYQCICHNGFKASQDQTMCM---DVDECERHPC 1943
GSY+C C GF + C+ V E+ PC
Sbjct: 320 GSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
Score = 50.1 bits (118), Expect = 3e-05
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 1447 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
C D++EC +C NG+CLN G+YRC C++GF P SC
Sbjct: 298 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 48.5 bits (114), Expect = 9e-05
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 27/135 (20%)
Query: 1067 GRPFYKDI-NEC-KAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPD 1124
GR F + I ++C KA PG+ C T+G+ + GF +C P
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-----SWGF---------NKCQKCPKKPS 276
Query: 1125 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCD 1184
G + EC GY+ + C DI+EC+ + C G C+NT GS++C
Sbjct: 277 YHGYNQMM--------ECLPGYKR--VNNTFCQDINECQLQGV-CPNGECLNTMGSYRCT 325
Query: 1185 CPLGHELSPSREDCV 1199
C +G P+ CV
Sbjct: 326 CKIGFGPDPTFSSCV 340
Score = 46.2 bits (108), Expect = 5e-04
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 29/139 (20%)
Query: 1919 CHNGFKASQDQTMCMDVDECE-RHPCGNGTCKNTVGSYNCLCYPGF--ELTHNNDCLD-- 1973
C G+K + T C D++EC+ + C NG C NT+GSY C C GF + T ++ D
Sbjct: 286 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 1974 --IDECSSFFGQVCRNGRCFNEIG----SFKCLCNEGYELTPDGKNCIDTNECVALPGSC 2027
+E + V +C + + C C+ G P + C LPG+
Sbjct: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC-------PLPGT- 396
Query: 2028 SPGTCQNLEGSFRCICPPG 2046
+F+ ICP G
Sbjct: 397 ---------AAFKEICPGG 406
Score = 45.4 bits (106), Expect = 8e-04
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 34/141 (24%)
Query: 1813 KEIPGICANGVCINQIGSF----RCE-CPTGFSY---NDLL-----------LVCEDIDE 1853
K +PG+ C +G+ +C+ CP SY N ++ C+DI+E
Sbjct: 244 KALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINE 303
Query: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN-GACV--------DRNECLEIPN--- 1901
C +C N +C+N+ GSYRC C GF P +CV ++ C + +
Sbjct: 304 CQL-QGVCP-NGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGR 361
Query: 1902 VCSHGLCVDLQGSYQCICHNG 1922
C H L V L C C G
Sbjct: 362 QCMHPLSVHLT-KQLCCCSVG 381
Score = 45.4 bits (106), Expect = 8e-04
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTY----QCSCNPGYQATPDRQGCTDIDECMIMN 1250
+EDC S N C+ KC + C PGY+ + C DI+EC +
Sbjct: 252 QEDCCGTVGTSWGFNKCQ--KCPKKPSYHGYNQMMECLPGYKRV-NNTFCQDINECQLQG 308
Query: 1251 GGCDTQCTNSEGSYECSCSEGYALMPDGRSC 1281
+ +C N+ GSY C+C G+ P SC
Sbjct: 309 VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 45.1 bits (105), Expect = 0.001
Identities = 36/134 (26%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 2557 KCPPGFTQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC--- 2612
+C PG+ + ++T C D NEC Q +C G C NT GS+ C C+ GF D T +C
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 342
Query: 2613 -----EDVDEC----DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2663
E+ C +C H L C C G +C +
Sbjct: 343 PPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEI 402
Query: 2664 CGSASCYNTLGSYK 2677
C Y G ++
Sbjct: 403 CPGGMGYTVSGVHR 416
Score = 43.5 bits (101), Expect = 0.003
Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1323 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC 1365
C D+NEC L +C GEC NT GS+ C C++G+ + C
Sbjct: 298 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 43.1 bits (100), Expect = 0.004
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
C GY + + C DI+EC+ +C G+C N G YRC C GF +C+
Sbjct: 286 CLPGYKRV-NNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Score = 42.4 bits (98), Expect = 0.007
Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 2454 KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSY 2513
K +P L C T+G+ F K C + PK +Y N
Sbjct: 244 KALPGLSKQEDCCGTVGTSWGFNK-----------------CQKCPKKPSYHGYNQ---- 282
Query: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHT--ACID 2571
C GY + + C+D++ECQ + C+NT+G + C C GF T +C+
Sbjct: 283 MMECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP 341
Query: 2572 NNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECDGNH 2622
+ P + KG C S +C S+ T L C V + G H
Sbjct: 342 D-----PPVISEEKGPCYRLVSS-GRQCMHPLSVHLTKQLCCCSVGKAWGPH 387
Score = 41.2 bits (95), Expect = 0.015
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDV-------DECA 1454
N C D++EC N +C+NT GSYRC C GF D S V +E
Sbjct: 294 NNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG 351
Query: 1455 ENINLCENG-QCLNVPGAY----RCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNL 1509
L +G QC++ + C C +G C +F+ IC G +
Sbjct: 352 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV 411
Query: 1510 PGM 1512
G+
Sbjct: 412 SGV 414
Score = 40.8 bits (94), Expect = 0.020
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 110 CIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQ--CSVRCMNGGTCAD-DHCQC 166
C C+NSC G +G + T + + + C + CMNGG C+ D CQC
Sbjct: 39 CTKGSCQNSCEKG---NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQC 95
Query: 167 QKGYIGTYCGQPV 179
+ G C PV
Sbjct: 96 PPNFTGKLCQIPV 108
Score = 38.5 bits (88), Expect = 0.098
Identities = 62/290 (21%), Positives = 93/290 (32%), Gaps = 64/290 (22%)
Query: 158 TCADDHCQ--CQKGYIGTYCGQP---------------VCENGCQNGGRCIGPNRCACVY 200
TC CQ C+KG T + +C C NGG+C ++C C
Sbjct: 38 TCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCP- 96
Query: 201 GFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATI-GRAWG-------HPCE 252
P FT ++CQ + G K + G+A G H
Sbjct: 97 --------------PNFT---GKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLP 139
Query: 253 MCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSET 312
+ Q + F PNI + E I+ V + P G K E
Sbjct: 140 LTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ---------IHQVSRIDG--PTGQKTKEA 188
Query: 313 TQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVN 372
+ + +T ++ S+ V P Y + + G CF +
Sbjct: 189 QPGQSQVSYQGLPVQKTQT---IHSTYSHQQVIPHVYPVAAK------TQLGRCFQETIG 239
Query: 373 GRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLP 422
+C + LPG + CC G WG + CP + S M+ LP
Sbjct: 240 SQCGKALPGLSKQEDCCGTVGTSWGFNKC-QKCPKKPSYHGYNQMMECLP 288
Score = 35.8 bits (81), Expect = 0.64
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1399
C GY + T C D++EC++ + CLN GS++C+C+ G+
Sbjct: 286 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 330
Score = 35.8 bits (81), Expect = 0.64
Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQD 528
Q I+ C+ +C NG C+ T+ SYRC C +G+ D
Sbjct: 299 QDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 34.7 bits (78), Expect = 1.4
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 2498 SPKPCNYICKNTEGSYQCSCPRGY---VLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
+P C C T+GS Q SC +G ++ E+G L + C C+N GG
Sbjct: 31 TPSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQ 86
Query: 2555 T-----CKCPPGFT 2563
C+CPP FT
Sbjct: 87 CSSRDKCQCPPNFT 100
Score = 33.1 bits (74), Expect = 4.1
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 2693 CHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
C D+NEC N C NT G Y C C G+
Sbjct: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 461 bits (1186), Expect = e-129
Identities = 486/1731 (28%), Positives = 675/1731 (38%), Gaps = 426/1731 (24%)
Query: 1087 GKCRNTI----GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECEC 1142
G C++++ F CRC GF +C+ D C SP G+ V G F C C
Sbjct: 91 GVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
Query: 1143 FEGYESGFMMMKNCM-DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDI 1201
GY+ ++C D+DEC GGTC+NT GSF+C CP G+ V
Sbjct: 147 PPGYQG-----RSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 200
Query: 1202 NECSLSDNLCRNGKCVNMIG--TYQCSCNPGYQATPDRQGC-TDIDEC---MIMNGGCDT 1255
C+ S CRNG G TY C+C PG++ Q C ++D+C +NGG
Sbjct: 201 --CAPSP--CRNGGTCRQSGDLTYDCACLPGFEG----QNCEVNVDDCPGHRCLNGGT-- 250
Query: 1256 QCTNSEGSYECSCSEGYALMPDGRSCA-DIDECENNPDIC-DGGQCTNIPGEYRCLCYDG 1313
C + +Y C C + G+ C D+DEC+ P+ C +GG C N G + C+C +G
Sbjct: 251 -CVDGVNTYNCQCPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 305
Query: 1314 FMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDECE 1372
+ ++C N D + +C G C + SF C C +G K G C D C
Sbjct: 306 WTG----ESCSQ-NIDDCATAVCFHGATCHDRVASFYCACPMG---KTGLL-CHLDDACV 356
Query: 1373 IGAHNCDMHASCLNIP--GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1430
++ C A C P G C+C G+ G G D+DECS G + C +CVNT G
Sbjct: 357 --SNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQG 413
Query: 1431 SYRCACSEGFTGDGFTCSDVDECAENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRSC 1489
S+ C C G+TG +DV+EC C N CL+ G + C C GFT C
Sbjct: 414 SFLCQCGRGYTGPRCE-TDVNECLS--GPCRNQATCLDRIGQFTCICMAGFT----GTYC 466
Query: 1490 Q-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGL- 1546
+ DIDEC G C + F C C G+ +G C D+DECA C NG
Sbjct: 467 EVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECAS-TPCRNGAK 521
Query: 1547 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 1606
CV+ P YEC C F+ G C D V +C P C G++ SC
Sbjct: 522 CVDQPDGYECRCAEGFE----GTLC-DRNVDDC----SPDPCHHGRCVD----GIASFSC 568
Query: 1607 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ-GGN 1665
C+ G G CE+ +DEC+ P C+ GG
Sbjct: 569 ACAPGYT-GTRCES-----------------------------QVDECRSQP--CRHGGK 596
Query: 1666 CINTFGSFQCECPQGYYLSEDTRI-CE-DIDECFAHPGVCGPGTCYNTLGNYTCICPPEY 1723
C++ + C CP G T + CE +ID+C ++P C G C + + Y C+C P +
Sbjct: 597 CLDLVDKYLCRCPSG-----TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF 649
Query: 1724 ------MQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPC- 1776
+++N + C NG C P +C + PC
Sbjct: 650 TGPLCNVEINECASSPCGEGGSCVDGENGFRC--LCPPGSLPPLCLPP-------SHPCA 700
Query: 1777 -EPC------PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIG 1829
EPC PG F+ +C PG++ +++ D C+ P A G C +
Sbjct: 701 HEPCSHGICYDAPG--GFRCVCE--PGWS-GPRCSQSLARDACESQP-CRAGGTCSSDGM 754
Query: 1830 SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYR-CECAAGFKLSPNG 1888
F C CP G CE + C+ N C+ C ++PG C C G++ P
Sbjct: 755 GFHCTCPPGVQGRQ----CELLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGWQ-GPR- 806
Query: 1889 ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA-SQDQTMCMDVDECERHPCGN-G 1946
D +EC HG+C +L GS+ C CH G+ S DQ D+++C+ +PC N G
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ----DINDCDPNPCLNGG 862
Query: 1947 TCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYE 2006
+C++ VGS++C C PGF D+DEC S C G C + + SF C C GY
Sbjct: 863 SCQDGVGSFSCSCLPGF--AGPRCARDVDECLS---NPCGPGTCTDHVASFTCTCPPGY- 916
Query: 2007 LTPDGKNC-IDTNECVALPGSC-SPGTCQNLEGSFRCICPPGYEVKSENC-IDINECDED 2063
G +C D +C P SC + GTC + SF C+C PGY +C + + C
Sbjct: 917 ---GGFHCEQDLPDC--SPSSCFNGGTCVDGVNSFSCLCRPGY--TGAHCQHEADPCLSR 969
Query: 2064 PNICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTN--FENGKCSVPKAFN 2120
P CL G C+ GF+C C F G +C T +C G+C
Sbjct: 970 P--CLHGGVCSAAHPGFRCTCLESF----TGPQC-QTLVDWCSRQPCQNGGRCV------ 1016
Query: 2121 TTKAKCCCSKMPGEGWGD--------PCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
T A C C GW PC V + LC G
Sbjct: 1017 QTGAYCLCP----PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAG-------------- 1058
Query: 2173 NECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGN-GTCTNV 2231
GQC++ D S C CP G TG C + + PC + GTC
Sbjct: 1059 ------------GQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGY 1102
Query: 2232 IGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCP---IGYALRE 2287
+G + C C G+ NCE D++ECA P C++ Y C+CP +G
Sbjct: 1103 MGGYMCECLPGYNGD---NCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
Query: 2288 DQKMC---KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECR 2343
++ C LD LH+ C +L+G F C CPPG G C D NECR
Sbjct: 1160 NEDDCGPGPPLDSGPRCLHN-----GTCVDLVGGFRCTCPPGYT----GLRCEADINECR 1210
Query: 2344 TKPGICENGRCVNII----GSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMAS 2399
+ G C + + G +RC C+ GF SG C QT+
Sbjct: 1211 S--GACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRC-------------QTVLSPC- 1250
Query: 2400 SSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNL 2459
+S+ C GG QC P PG
Sbjct: 1251 -------ESQPCQHGG-----QCRPSPGPGGGL--------------------------- 1271
Query: 2460 CTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL-DECSQSPKPCNYICKNTEGSYQCSCP 2518
+F C C + G C + C + P C+ T +C+CP
Sbjct: 1272 -----------TFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACP 1316
Query: 2519 RGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQ 2578
G G +C+ PPG N C +
Sbjct: 1317 PGL----SGPSCRSFP----------------------GSPPG--------ASNASCAAA 1342
Query: 2579 PSLCGAKGICQNTPGS--FSCECQRGFSLDATGLNCE---DVDECDGNHRC-QHGCQNIL 2632
P L G G C+ P + F C C +G+ TG CE E RC + CQ
Sbjct: 1343 PCLHG--GSCRPAPLAPFFRCACAQGW----TGPRCEAPAAAPEVSEEPRCPRAACQAKR 1396
Query: 2633 GGYRC-------GCPQGYIQHYQWNQCVDENECS----NP-NACGSASCYNTLGSYKC-- 2678
G RC GC W D +CS +P C + C+ + +C
Sbjct: 1397 GDQRCDRECNSPGC--------GW----DGGDCSLSVGDPWRQCEALQCWRLFNNSRCDP 1444
Query: 2679 ACPS-GFSFDQF-------SSACHDVNE--CSS--SKNPCNYGCSNTEGGY 2717
AC S +D F C+ V E C+ + C+ GC+ E G+
Sbjct: 1445 ACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGW 1495
Score = 431 bits (1107), Expect = e-120
Identities = 410/1387 (29%), Positives = 563/1387 (40%), Gaps = 299/1387 (21%)
Query: 1406 CIDLDECSNGTHQCSINAQCVNTPG-SYRCACSEGFTGDGFTCSDVDECAENINLCENGQ 1464
C+D C+NG +C P C C G+ G+ C D C G
Sbjct: 43 CLDGSPCANG-------GRCTQLPSREAACLCPPGWVGE--RCQLEDPCHSG-PCAGRGV 92
Query: 1465 CLN--VPGAYR--CECEMGFTPASDSRSCQDIDECSFQNICVFGT-CNNLP-GMFHCICD 1518
C + V G R C C GF C D C + C G C+ P G F C C
Sbjct: 93 CQSSVVAGTARFSCRCPRGFR----GPDCSLPDPC-LSSPCAHGARCSVGPDGRFLCSCP 147
Query: 1519 DGYELDRTGGNC-TDIDECADPINCVNG-LCVNTPGRYECNCPPDFQLNPTGVGCVDNRV 1576
GY+ G +C +D+DEC C +G C+NTPG + C CP + TG C + V
Sbjct: 148 PGYQ----GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCENPAV 199
Query: 1577 GNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE---TCPPVNSTEYYTLC 1633
C S PC TC Y C
Sbjct: 200 ----------------------------PCAPS-------PCRNGGTCRQSGDLTYDCAC 224
Query: 1634 -PGGEGFRPNPITIILEDIDECQELPG--LCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
PG EG ++D+C PG GG C++ ++ C+CP + + C
Sbjct: 225 LPGFEGQNCEV------NVDDC---PGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFC 271
Query: 1691 -EDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTT 1748
ED+DEC P C GTC+NTLG ++C+C + + N D + C+ +G T
Sbjct: 272 TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF---HGAT 328
Query: 1749 CENEL-------PFNVTKRMC----CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGF 1797
C + + P T +C C N + C+ P G A IC PGF
Sbjct: 329 CHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE-DAICDTNPVNGRA----ICTCPPGF 383
Query: 1798 TFDIHTGKAVD--IDECKEIPGICAN-GVCINQIGSFRCECPTGFSYNDLLLVCE-DIDE 1853
T G A D +DEC C + G C+N GSF C+C G++ CE D++E
Sbjct: 384 T-----GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR----CETDVNE 434
Query: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQG 1913
C +G C+ A C++ G + C C AGF + VD +EC P V + G+C D
Sbjct: 435 CLSGP--CRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQSSPCV-NGGVCKDRVN 489
Query: 1914 SYQCICHNGFKASQDQTMCMDVDECERHPCGNGT-CKNTVGSYNCLCYPGFELTHNNDCL 1972
+ C C +GF S Q +DVDEC PC NG C + Y C C GFE T +
Sbjct: 490 GFSCTCPSGFSGSTCQ---LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR-- 544
Query: 1973 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGT 2031
++D+CS C +GRC + I SF C C GY G C +EC + P G
Sbjct: 545 NVDDCSP---DPCHHGRCVDGIASFSCACAPGYT----GTRCESQVDECRSQPCRHG-GK 596
Query: 2032 CQNLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLS 2090
C +L + C CP G NC ++I++C +P C FG C + + C+C PGF
Sbjct: 597 CLDLVDKYLCRCPSG--TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFT-- 650
Query: 2091 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
G C N E +C+ + C G G C D E
Sbjct: 651 --GPLC----------NVEINECA--------SSPC--------GEGGSCV----DGENG 678
Query: 2151 FQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVR 2210
F+ LCP G++P L + C P CS+G C + G FRC C G++ G R
Sbjct: 679 FRCLCP--PGSLPPL--CLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWS----GPR 728
Query: 2211 CVDT---DECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAF 2266
C + D C PC GTC++ F C C G + CE ++ C NP
Sbjct: 729 CSQSLARDACE-SQPCRAGGTCSSDGMGFHCTCPPGVQG---RQCELLSPCTPNPCEHGG 784
Query: 2267 RCMNTFGSYE-CTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
RC + G C+CP G+ + + +D+DECA G C G+ C NL G+F C C
Sbjct: 785 RCESAPGQLPVCSCPQGW---QGPRCQQDVDECA-GPAPCGPHGI-CTNLAGSFSCTCHG 839
Query: 2326 GMARRPDGEGC-VDENECRTKPGICENGRCVNIIGSYRCECNEGF---QSSSSGTECLDN 2381
G G C D N+C P + G C + +GS+ C C GF + + ECL N
Sbjct: 840 GYT----GPSCDQDINDCDPNPCL-NGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSN 894
Query: 2382 RQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGP 2441
G + + V C C G G G CE
Sbjct: 895 PCG-------------PGTCTDHVASFTCTCPPGYG-GFHCE------------------ 922
Query: 2442 GYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTSCI-DLDECSQSP 2499
+D+ +C P+ C NG C++ + SF C C+ GYT G C + D C P
Sbjct: 923 ------QDLPDCS--PSSCFNGGTCVDGVNSFSCLCRPGYT----GAHCQHEADPCLSRP 970
Query: 2500 KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL-DECQTKQHNCQFLCVNTLGGFTCKC 2558
+C ++C+C + G C+ L D C + CV T G C C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFT----GPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLC 1024
Query: 2559 PPGFTQH--HTACIDNNECGSQ-----PSLCGAKGICQNTPGSFSCECQRGFSLDATGLN 2611
PPG++ + E +Q LC A G C + S C C G TG +
Sbjct: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSH 1080
Query: 2612 CE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDE-NECSNPNACGSA 2667
CE +VD C CQHG C+ +GGY C C GY + C D+ +EC++
Sbjct: 1081 CEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQPCQHGG 1135
Query: 2668 SCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNP-------C--NYGCSNTEGGYL 2718
SC + + Y C+CP G C ++NE P C N C + GG+
Sbjct: 1136 SCIDLVARYLCSCPPG----TLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR 1190
Query: 2719 CGCPPGY 2725
C CPPGY
Sbjct: 1191 CTCPPGY 1197
Score = 401 bits (1031), Expect = e-111
Identities = 412/1545 (26%), Positives = 584/1545 (37%), Gaps = 301/1545 (19%)
Query: 645 PGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
PG P C D C G C C CPPG G C +
Sbjct: 36 PGAAAPP----CLDGSPCANGGRCTQ----LPSREAACLCPPGWV----GERC---QLED 80
Query: 705 TCYGG--IKKGVCVRPFPGAVTKSECCCAN----PDYGFGEPCQPCPAKNSAEFHGLCSS 758
C+ G +GVC + C C PD +PC P + A
Sbjct: 81 PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGAR------- 133
Query: 759 GVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVN 817
C++ PD G + C+C GY+ GR+C D+DEC V
Sbjct: 134 -------------CSVGPD-----------GRFLCSCPPGYQ----GRSCRSDVDECRVG 165
Query: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED-INECESNPCVNGACRNNLGSFNCE 876
G C NTPGS+ C CP GY CE+ C +PC NG G +
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAPSPCRNGGTCRQSGDLTYD 221
Query: 877 CSPGSKLSSTGLICIDSLKG-TCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERC 935
C+ C+ +G C +N+ D +NG T G C
Sbjct: 222 CA-----------CLPGFEGQNCEVNVDDCPGHRCLNGGTCVD----------GVNTYNC 260
Query: 936 ELDTACPRGLARIKGVTC-EDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGR 993
+ CP G C EDV+EC++ P C N G C N+ G C C G T + +
Sbjct: 261 Q----CP---PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQ 313
Query: 994 VCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC---EECPKPGTKEYET 1050
D C+ H F C C +G G C + C E +
Sbjct: 314 NIDDCATAVCF----HGATCHDRVASF---YCACPMGKT-GLLCHLDDACVSNPCHE-DA 364
Query: 1051 LCP----RGAGFANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFKCRCNSGFA 1105
+C G TG +D++EC C + G+C NT GSF C+C G+
Sbjct: 365 ICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT 424
Query: 1106 LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERN 1165
R TD++EC +S C++ G F C C G+ + +DIDEC+ +
Sbjct: 425 ---GPRCETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCE----VDIDECQSS 476
Query: 1166 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQ 1224
P + GG C + F C CP G S + +D++EC+ + CRNG KCV+ Y+
Sbjct: 477 PCV-NGGVCKDRVNGFSCTCPSGFSGSTCQ---LDVDECASTP--CRNGAKCVDQPDGYE 530
Query: 1225 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-AD 1283
C C G++ T + D +G +C + S+ C+C+ GY G C +
Sbjct: 531 CRCAEGFEGTLCDRNVDDCSPDPCHHG----RCVDGIASFSCACAPGYT----GTRCESQ 582
Query: 1284 IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECEN 1343
+DEC + P GG+C ++ +Y C C G +VN D SN C FG C +
Sbjct: 583 VDECRSQP-CRHGGKCLDLVDKYLCRCPSGTTG-----VNCEVNIDDCASNPCTFGVCRD 636
Query: 1344 TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNG 1403
+ C CQ G++ G +++EC + C SC++ F+C C G
Sbjct: 637 GINRYDCVCQPGFT---GPLCNVEINEC--ASSPCGEGGSCVDGENGFRCLCPPG----S 687
Query: 1404 IKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENG 1463
+ + L H+ + C + PG +RC C G++G + S + E+ G
Sbjct: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
Query: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVF-GTCNNLPGMFH-CICDDGY 1521
C + + C C P R C+ + C+ N C G C + PG C C G+
Sbjct: 748 TCSSDGMGFHCTC----PPGVQGRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGW 802
Query: 1522 ELDRTGGNC-TDIDECADPINC-VNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC 1579
+ G C D+DECA P C +G+C N G + C C + TG C D + +C
Sbjct: 803 Q----GPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC 853
Query: 1580 ----YLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPC--ETCPPVNSTEYYTLC 1633
L G DG S + G + C + + NPC TC ++ T
Sbjct: 854 DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCP 913
Query: 1634 PGGEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRICED 1692
PG GF +D+ +C P C GG C++ SF C C GY +
Sbjct: 914 PGYGGFHCE------QDLPDCS--PSSCFNGGTCVDGVNSFSCLCRPGY---TGAHCQHE 962
Query: 1693 IDECFAHP----GVCG---PG---TCYNTLGNYTC-----ICPPEYMQVNGGHNCMDMRK 1737
D C + P GVC PG TC + C C + Q NGG
Sbjct: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ-NGGRCVQTGAY 1021
Query: 1738 SFCYRSYNGTTCE-NELP-------FNVTKRMCC--------------CTYNVGKAWN-- 1773
C ++G C+ LP V C C G+ +
Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHC 1081
Query: 1774 ----KPC--EPCPTPGTADFKT---ICGNIPGFTFDIHTGKAVDIDECKEIPGICAN-GV 1823
PC +PC GT +C +PG+ D D+DEC P C + G
Sbjct: 1082 EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGD---NCEDDVDECASQP--CQHGGS 1136
Query: 1824 CINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNL-----CQRNADCINSPGSYRCE 1877
CI+ + + C CP G L ++CE + D+C G L C N C++ G +RC
Sbjct: 1137 CIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT 1192
Query: 1878 CAAGFKLSPNGACVDRNECLEIPNVCSH--GLCVDLQGSYQCICHNGFKASQDQTMCMDV 1935
C G+ + D NEC +H D G ++C+CH GF + QT+ +
Sbjct: 1193 CPPGY--TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTV---L 1247
Query: 1936 DECERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEI 1994
CE PC + G C+ + G PG LT C F+G C R
Sbjct: 1248 SPCESQPCQHGGQCRPSPG-------PGGGLTFTCHC-----AQPFWGPRCE--RVARSC 1293
Query: 1995 GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC 2054
+C + TP G C A P S +C++ GS PPG S
Sbjct: 1294 RELQCPVGVPCQQTPRGPRC-------ACPPGLSGPSCRSFPGS-----PPGASNAS--- 1338
Query: 2055 IDINECDEDPNICLF-GSCTNTPGG--FQCLCPPGFVLSDNGRRC 2096
C P CL GSC P F+C C G+ G RC
Sbjct: 1339 -----CAAAP--CLHGGSCRPAPLAPFFRCACAQGW----TGPRC 1372
Score = 367 bits (941), Expect = e-100
Identities = 378/1355 (27%), Positives = 534/1355 (39%), Gaps = 291/1355 (21%)
Query: 517 YRCECNMGYKQDANGDCIDVDECTSNPCTNGD--CVNTPGSYYCKCHAGFQRTPTKQACI 574
+ C C G++ DC D C S+PC +G V G + C C G+Q +
Sbjct: 104 FSCRCPRGFR---GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS--- 157
Query: 575 DIDECIQNGVLCKNG-RCVNTDGSFQCICNAGF--------------------------- 606
D+DEC + G C++G C+NT GSF+C C AG+
Sbjct: 158 DVDEC-RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG 216
Query: 607 ELTTD--------GKNC-VDHDECTTTNMCLN-GMCINEDGSFKCICKPGFVLAPNGRYC 656
+LT D G+NC V+ D+C + CLN G C++ ++ C C P + G++C
Sbjct: 217 DLTYDCACLPGFEGQNCEVNVDDC-PGHRCLNGGTCVDGVNTYNCQCPPEW----TGQFC 271
Query: 657 T-DVDECQ-TPGICMN-GHCINSEGSFRCDCPPG-----LAVGMDGRVCVDTHMRSTCYG 708
T DVDECQ P C N G C N+ G C C G + +D +TC+
Sbjct: 272 TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHD 331
Query: 709 GIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQP---CPAKNSAEFHGLCSSGVGIT-- 763
+ C P + K+ C D PC C N +C+ G T
Sbjct: 332 RVASFYCACP----MGKTGLLCHLDDACVSNPCHEDAICDT-NPVNGRAICTCPPGFTGG 386
Query: 764 VDGRDINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLC 821
+D++EC++ + C + G C N +GS+ C C GY +G C D++ECL C
Sbjct: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECLSGP--C 440
Query: 822 DN-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSP 879
N C + G ++C C G+ T T DI+EC+S+PCVN G C++ + F+C C
Sbjct: 441 RNQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
Query: 880 GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC--ERCEL 937
G S TC L++ + CA+ G+ C +
Sbjct: 498 GFSGS------------TCQLDVDE----------------CASTPCRNGAKCVDQPDGY 529
Query: 938 DTACPRGLARIKGVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCL 996
+ C G +G C+ +V++C P C +GRCV+ SF C C G TG C
Sbjct: 530 ECRCAEG---FEGTLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGY----TGTRC- 579
Query: 997 DIRMEQCYLKWDEDECIHPVPGKFRMD--ACCCAVGAAWGTECE----ECP--------- 1041
+ ++++C C H +D C C G G CE +C
Sbjct: 580 ESQVDEC----RSQPCRHGGKCLDLVDKYLCRCPSGTT-GVNCEVNIDDCASNPCTFGVC 634
Query: 1042 KPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCN 1101
+ G Y+ +C G TG +INEC + P G C + F+C C
Sbjct: 635 RDGINRYDCVCQPG---------FTGPLCNVEINECASSP-CGEGGSCVDGENGFRCLCP 684
Query: 1102 SGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE 1161
G + C P C GIC + PG F C C G+ + D
Sbjct: 685 PG---SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSG--PRCSQSLARDA 737
Query: 1162 CERNPLLCR-GGTCVNTEGSFQCDCPLGHE------LSP-SREDC--------------- 1198
CE P CR GGTC + F C CP G + LSP + C
Sbjct: 738 CESQP--CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPV 795
Query: 1199 -------------VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDE 1245
D++EC+ +G C N+ G++ C+C+ GY Q D D
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 1246 CMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCA-DIDECENNPDICDGGQCTNIPG 1304
+NGG C + GS+ CSC G+A G CA D+DEC +NP C G CT+
Sbjct: 856 NPCLNGG---SCQDGVGSFSCSCLPGFA----GPRCARDVDECLSNP--CGPGTCTDHVA 906
Query: 1305 EYRCLC---YDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKG 1361
+ C C Y GF D+ C S+ G C + SF C C+ GY+ G
Sbjct: 907 SFTCTCPPGYGGFHCEQDLPDCSP-------SSCFNGGTCVDGVNSFSCLCRPGYT---G 956
Query: 1362 TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSI 1421
+ D C + C C F+C+C E + G + + +D CS C
Sbjct: 957 AHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTL-VDWCSR--QPCQN 1011
Query: 1422 NAQCVNTPGSYRCACSEGFTGD--GFTCSDVDECAENI-----NLCE-NGQCLNVPGAYR 1473
+CV T G+Y C C G++G E A I LC+ GQC++ ++
Sbjct: 1012 GGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1069
Query: 1474 CECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TD 1532
C C G T S Q++D C Q GTC G + C C GY G NC D
Sbjct: 1070 CVCPEGRT---GSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDD 1122
Query: 1533 IDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC----YLKFGPRGD 1588
+DECA G C++ RY C+CPP GV C N +C L GPR
Sbjct: 1123 VDECASQPCQHGGSCIDLVARYLCSCPP----GTLGVLCEINE-DDCGPGPPLDSGPRCL 1177
Query: 1589 GSLSCNTEIG-------VGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFR- 1640
+ +C +G G + C + + C T PGG GFR
Sbjct: 1178 HNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAA----HTRDCLQDPGG-GFRC 1232
Query: 1641 --------PNPITIILEDIDECQELPGLCQ-GGNCINTFG-----SFQCECPQGYYLSED 1686
P T+ + C+ P CQ GG C + G +F C C Q ++
Sbjct: 1233 LCHAGFSGPRCQTV----LSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1286
Query: 1687 TRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPP 1721
R+ E GV C T C CPP
Sbjct: 1287 ERVARSCRELQCPVGV----PCQQTPRGPRCACPP 1317
Score = 362 bits (929), Expect = 3e-99
Identities = 426/1620 (26%), Positives = 602/1620 (37%), Gaps = 377/1620 (23%)
Query: 125 SRPNMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADD--------HCQCQKGYIGTYC 175
SR C C G + C + C S C G C C+C +G+ G C
Sbjct: 60 SREAACLCPPGWVGERCQLED--PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Query: 176 G--QPVCENGCQNGGRC-IGPNR---CACVYGFTGPQCERDY---RTGPCFTQVNNQMCQ 226
P + C +G RC +GP+ C+C G+ G C D R G + C+
Sbjct: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG--------EPCR 169
Query: 227 GQLTGIVCTKTLCCATIGRAWGHPCE--MCPAQPQPCRRG--------------FIPNIR 270
T + + C G CE P P PCR G +P
Sbjct: 170 HGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFE 229
Query: 271 TGACQ-DVDECQAIPG--ICQGGNCINTVGSFECRCPAGHKQSETTQKC-EDIDECSIIP 326
C+ +VD+C PG GG C++ V ++ C+CP T Q C ED+DEC + P
Sbjct: 230 GQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPP----EWTGQFCTEDVDECQLQP 282
Query: 327 GICETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTK 385
C G C NT+G + CVC G+ + D T +CF G R+
Sbjct: 283 NACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT-------CHDRVAS 335
Query: 386 MQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGN----- 440
C C G+ + + +AC E +C D P+ G PG TGG
Sbjct: 336 FYCACPMGKTGLLCHLDDACVSNPCHE-DAIC-DTNPVNG-RAICTCPPGFTGGACDQDV 392
Query: 441 -----GFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQ-- 493
G P + G G G G++ V GP T L++
Sbjct: 393 DECSIGANPCEH-LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIG 451
Query: 494 ---------------TIDICKHHANLCLNGR-CIPTVSSYRCECNMGYKQDANGDC-IDV 536
+DI + ++ C+NG C V+ + C C G+ + C +DV
Sbjct: 452 QFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF---SGSTCQLDV 508
Query: 537 DECTSNPCTNG-DCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTD 595
DEC S PC NG CV+ P Y C+C GF+ T + ++D+C + C +GRCV+
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR---NVDDCSPDP--CHHGRCVDGI 563
Query: 596 GSFQCICNAGFELT----------------------------------TDGKNC-VDHDE 620
SF C C G+ T T G NC V+ D+
Sbjct: 564 ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD 623
Query: 621 CTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGS 679
C +N C G+C + + C+C+PGF G C +++EC + G C++ E
Sbjct: 624 C-ASNPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINECASSPCGEGGSCVDGENG 678
Query: 680 FRCDCPPGLAVGM-------------DGRVCVDT--HMRSTCYGGIKKGVCVRPFPGAVT 724
FRC CPPG + +C D R C G C +
Sbjct: 679 FRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 725 KSECC-----CANPDYGF---------GEPCQ---PCPAKNSAEFHGLCSSGVG-ITVDG 766
+S+ C C++ GF G C+ PC N E G C S G + V
Sbjct: 739 ESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC-TPNPCEHGGRCESAPGQLPVCS 797
Query: 767 -----------RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDEC 814
+D++ECA +GIC NL GS+ C C+ GY +G +C DI++C
Sbjct: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDC 853
Query: 815 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFN 874
N L + G C++ GS+SC+C PG+ D++EC SNPC G C +++ SF
Sbjct: 854 DPNPCL-NGGSCQDGVGSFSCSCLPGF---AGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 875 CECSPGSKLSSTGLICIDSLK----------GTC--WLNIQDSRCEVNINGATLKSEC-- 920
C C PG G C L GTC +N C GA + E
Sbjct: 910 CTCPPG----YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP 965
Query: 921 CATLGAAWGSPCERCELDTACPRGLARIKGVTCED-VNECEVFPGVCPN-GRCVNSKGSF 978
C + G C C L G C+ V+ C P C N GRCV +
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRC-TCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT--GA 1020
Query: 979 HCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECE 1038
+C CP G +GR+C DIR C E + R++ C A G
Sbjct: 1021 YCLCPPG----WSGRLC-DIRSLPC------REAAAQI--GVRLEQLCQAGG-------- 1059
Query: 1039 ECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFK 1097
+C + Y +CP G TG ++++ C A P C + G CR +G +
Sbjct: 1060 QCVDEDSSHY-CVCPEGR---------TGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYM 1107
Query: 1098 CRCNSGFALDMEERNC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNC 1156
C C G+ D NC D+DEC P G G C++ + C C G + +
Sbjct: 1108 CECLPGYNGD----NCEDDVDECASQPCQHG-GSCIDLVARYLCSC----PPGTLGVLCE 1158
Query: 1157 MDIDECERNPLLCRG------GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL 1210
++ D+C P L G GTCV+ G F+C CP G+ C N
Sbjct: 1159 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL----------RCEADINE 1208
Query: 1211 CRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSE 1270
CR+G C + T C +PG G + C C
Sbjct: 1209 CRSGAC-HAAHTRDCLQDPG-------------------------------GGFRCLCHA 1236
Query: 1271 GYALMPDGRSCADI-DECENNPDICD-GGQCTNIPG-----EYRCLCYDGFMASMDMKTC 1323
G++ G C + CE+ P C GGQC PG + C C F +
Sbjct: 1237 GFS----GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVA 1290
Query: 1324 IDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHA 1382
E C G C+ T C C G S C GA N A
Sbjct: 1291 RSCRELQ-----CPVGVPCQQTPRGPRCACPPGLS----GPSCRSFPGSPPGASNASCAA 1341
Query: 1383 S-CLN--------IPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ CL+ + F+C+C +GW G + + +C A C G R
Sbjct: 1342 APCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCP-RAACQAKRGDQR 1400
Query: 1434 C---ACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 1490
C S G DG CS + CE QC + RC+ PA S +
Sbjct: 1401 CDRECNSPGCGWDGGDCS--LSVGDPWRQCEALQCWRLFNNSRCD------PACSSPA-- 1450
Query: 1491 DIDECSFQNI-CVFG----TCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVN 1544
C + N C G TCN ++ C D + R C + +EC D ++C +
Sbjct: 1451 ----CLYDNFDCHAGGRERTCN---PVYEKYCADHFADGRCDQGC-NTEECGWDGLDCAS 1502
Score = 318 bits (816), Expect = 4e-86
Identities = 392/1469 (26%), Positives = 545/1469 (37%), Gaps = 293/1469 (19%)
Query: 354 DGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRG 409
+G RC + +C G V RC E P C G C G G + ++ V G
Sbjct: 51 NGGRCTQLPSREAACLCPPGWVGERCQLEDP---------CHSGPCAGRG-VCQSSVVAG 100
Query: 410 SEEYRRLCMDGL--PMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF 467
+ + C G P +P S P G GP G P
Sbjct: 101 TARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARC--------SVGPDGRFLCSCP----- 147
Query: 468 SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQ 527
PG G +D C+ G C+ T S+RC+C GY
Sbjct: 148 -PGYQGRSC---------------RSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTG 191
Query: 528 DANGDCIDVDECTSNPCTNGDCVNTPG--SYYCKCHAGFQRTPTKQAC-IDIDECIQNGV 584
+ C +PC NG G +Y C C GF+ Q C +++D+C G
Sbjct: 192 PLCEN--PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDC--PGH 243
Query: 585 LCKN-GRCVNTDGSFQCICNAGFELTTDGKNCV-DHDEC-TTTNMCLN-GMCINEDGSFK 640
C N G CV+ ++ C C + G+ C D DEC N C N G C N G
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
Query: 641 CICKPGFVLAPNGRYCT-DVDECQTPGICMNG-HCINSEGSFRCDCP---PGLAVGMD-- 693
C+C G+ G C+ ++D+C T +C +G C + SF C CP GL +D
Sbjct: 300 CVCVNGW----TGESCSQNIDDCAT-AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDA 354
Query: 694 --------GRVC----VDTHMRSTCYGGIKKGVCVRPFPGAVTKSECC-----CANPDYG 736
+C V+ TC G G C + + C C N
Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414
Query: 737 F---------GEPCQ----PC---PAKNSA-------EFHGLCSSGVGITVDGRDINECA 773
F G C+ C P +N A +F +C +G T DI+EC
Sbjct: 415 FLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQ 474
Query: 774 LDPDICAN-GICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGL-CRNTP 830
P C N G+C++ + C C SG+ SG C +D+DEC C NG C + P
Sbjct: 475 SSP--CVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECASTP--CRNGAKCVDQP 526
Query: 831 GSYSCTCPPGYVFRTETETCE-DINECESNPCVNGACRNNLGSFNCECSPG--------- 880
Y C C G+ E C+ ++++C +PC +G C + + SF+C C+PG
Sbjct: 527 DGYECRCAEGF----EGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQ 582
Query: 881 -----SKLSSTGLICIDSLKG---TCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC 932
S+ G C+D + C CEVNI+ CA+ +G
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD-------CASNPCTFGVCR 635
Query: 933 ERC-ELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDG 990
+ D C G G C ++NEC P G CV+ + F C CP G
Sbjct: 636 DGINRYDCVCQPGFT---GPLCNVEINECASSP-CGEGGSCVDGENGFRCLCPPG----S 687
Query: 991 TGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE------CPKPG 1044
+CL + C + PG FR C C G + G C + C
Sbjct: 688 LPPLCLPPSHPCAHEPCSHGIC-YDAPGGFR---CVCEPGWS-GPRCSQSLARDACESQP 742
Query: 1045 TKEYETLCPRGAGF-ANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFK-CRCN 1101
+ T G GF + GR + ++ C P C + G+C + G C C
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQ-CELLSPCT--PNPCEHGGRCESAPGQLPVCSCP 799
Query: 1102 SGFALDMEERNCTDIDECRISPDLCG-SGICVNTPGSFECECFEGYESGFMMMKNC-MDI 1159
G+ R D+DEC P CG GIC N GSF C C GY +C DI
Sbjct: 800 QGW---QGPRCQQDVDEC-AGPAPCGPHGICTNLAGSFSCTCHGGYTG-----PSCDQDI 850
Query: 1160 DECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCV-DINECSLSDNLCRNGKCVN 1218
++C+ NP L GG+C + GSF C C G + C D++EC N C G C +
Sbjct: 851 NDCDPNPCL-NGGSCQDGVGSFSCSCLPGF----AGPRCARDVDEC--LSNPCGPGTCTD 903
Query: 1219 MIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 1278
+ ++ C+C PGY Q D NGG C + S+ C C GY G
Sbjct: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGG---TCVDGVNSFSCLCRPGYT----G 956
Query: 1279 RSCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM 1337
C + D C + P + GG C+ +RC C + F +C + C
Sbjct: 957 AHCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESFTGP----------QCQTLVDWCS 1005
Query: 1338 FGECEN----TKGSFICHCQLGYSVKK---GTTGCTDVDECEIGA---HNCDMHASCLNI 1387
C+N + C C G+S + + C + +IG C C++
Sbjct: 1006 RQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREA-AAQIGVRLEQLCQAGGQCVDE 1064
Query: 1388 PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC 1447
S C C EG G+ + ++D C C C G Y C C G+ GD
Sbjct: 1065 DSSHYCVCPEGRTGSHCE-QEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDNCE- 1120
Query: 1448 SDVDECAENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDEC-------SFQ 1498
DVDECA C++ G C+++ Y C C P + C+ + D+C S
Sbjct: 1121 DDVDECAS--QPCQHGGSCIDLVARYLCSC----PPGTLGVLCEINEDDCGPGPPLDSGP 1174
Query: 1499 NICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPI--NCVNGLCVNTP-GRY 1554
GTC +L G F C C GY TG C DI+EC C+ P G +
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGF 1230
Query: 1555 ECNCPPDFQ-------LNP-TGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR--- 1603
C C F L+P C G C GP G + +C+ R
Sbjct: 1231 RCLCHAGFSGPRCQTVLSPCESQPC--QHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCER 1288
Query: 1604 -SSCCCSLGKAWGNPCE--------TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDEC 1654
+ C L G PC+ CPP S PG N C
Sbjct: 1289 VARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNA---------SC 1339
Query: 1655 QELPGLCQGGNC--INTFGSFQCECPQGY 1681
P L GG+C F+C C QG+
Sbjct: 1340 AAAPCL-HGGSCRPAPLAPFFRCACAQGW 1367
Score = 256 bits (654), Expect = 2e-67
Identities = 322/1192 (27%), Positives = 429/1192 (35%), Gaps = 268/1192 (22%)
Query: 89 CGSRFHS-YC-CPGWKT---LPGGNQCIVPICRNS--CGDGFCSRPNMCTCSSGQISSTC 141
C R S YC CP KT + C+ C C + +CTC G C
Sbjct: 329 CHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC 388
Query: 142 GSKSIQQCSVR---CMNGGTCADDH----CQCQKGYIGTYCGQPV--CENG-CQNGGRC- 190
+ + +CS+ C + G C + CQC +GY G C V C +G C+N C
Sbjct: 389 -DQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCL 447
Query: 191 --IGPNRCACVYGFTGPQCERDY---RTGPCFTQVNNQMCQGQLTGIVCT------KTLC 239
IG C C+ GFTG CE D ++ PC VN +C+ ++ G CT + C
Sbjct: 448 DRIGQFTCICMAGFTGTYCEVDIDECQSSPC---VNGGVCKDRVNGFSCTCPSGFSGSTC 504
Query: 240 CATIGRAWGHPCE---MCPAQPQ----PCRRGFIPNIRTGACQDVDECQAIPGICQGGNC 292
+ PC C QP C GF + ++VD+C P C G C
Sbjct: 505 QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTL---CDRNVDDCS--PDPCHHGRC 559
Query: 293 INTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYVT 351
++ + SF C C G+ T +CE +DEC P G+C + V Y C CP G
Sbjct: 560 VDGIASFSCACAPGY----TGTRCESQVDECRSQP-CRHGGKCLDLVDKYLCRCPSG--- 611
Query: 352 STDGSRC---IDQ------RTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIP 402
T G C ID G+C G+ C + PG T C E C
Sbjct: 612 -TTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQ-PG-FTGPLCNVEINECASSPCGE 668
Query: 403 EACPVRGSEEYRRLCMDG-LPMGGIP------------GSAGSRPGG------TGGNG-- 441
V G +R LC G LP +P G PGG G +G
Sbjct: 669 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPR 728
Query: 442 -----------FAPSGNGNGYGPGGTGF--IPIPGGNG-----FSPGV------GGAGVG 477
P G G GF PG G SP GG
Sbjct: 729 CSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCES 788
Query: 478 AGGQGPIIT-----GLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD 532
A GQ P+ + Q +D C A +G C S+ C C+ GY +
Sbjct: 789 APGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ 848
Query: 533 CIDVDECTSNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
D+++C NPC N G C + GS+ C C GF + D+DEC+ N C G C
Sbjct: 849 --DINDCDPNPCLNGGSCQDGVGSFSCSCLPGF---AGPRCARDVDECLSNP--CGPGTC 901
Query: 592 VNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLA 650
+ SF C C G+ G +C D +C+ ++ G C++ SF C+C+PG+
Sbjct: 902 TDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY--- 954
Query: 651 PNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGG 709
G +C + D C + G C + FRC C G + VD R C G
Sbjct: 955 -TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF-TGPQCQTLVDWCSRQPCQNG 1012
Query: 710 IKKGVCVRPFPGAVTKSECCCANPDYGFGE-------PCQPCPAKNSAEFHGLCSSGVGI 762
G CV+ T + C C P G PC+ A+ LC +G G
Sbjct: 1013 ---GRCVQ------TGAYCLC--PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAG-GQ 1060
Query: 763 TVD-----------GRDINECALDPDICA------NGICENLRGSYRCNCNSGYEPDASG 805
VD GR + C + D C G C G Y C C GY +G
Sbjct: 1061 CVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NG 1116
Query: 806 RNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP---- 860
NC D+DEC ++ G C + Y C+CPPG T CE INE + P
Sbjct: 1117 DNCEDDVDEC-ASQPCQHGGSCIDLVARYLCSCPPG----TLGVLCE-INEDDCGPGPPL 1170
Query: 861 -----CV-NGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGA 914
C+ NG C + +G F C C PG TGL C + + C A
Sbjct: 1171 DSGPRCLHNGTCVDLVGGFRCTCPPG----YTGLRCEADI----------NECRSGACHA 1216
Query: 915 TLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPG---------- 964
+C G + C C L+ + C+ +C PG
Sbjct: 1217 AHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCH 1276
Query: 965 --------------------VCPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIRME-- 1001
CP G C + C CP GL +G C
Sbjct: 1277 CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGL----SGPSCRSFPGSPP 1332
Query: 1002 -QCYLKWDEDECIH-------PVPGKFRMDACCCAVGAAW-GTECEECPKPGTKEYETLC 1052
C+H P+ FR C CA G W G CE E C
Sbjct: 1333 GASNASCAAAPCLHGGSCRPAPLAPFFR---CACAQG--WTGPRCEAPAAAPEVSEEPRC 1387
Query: 1053 PRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY--GKCRNTIGSFKCRCNS 1102
PR A A RGD R EC + PG C + G C ++G +C +
Sbjct: 1388 PRAACQAKRGDQRCDR-------ECNS-PG-CGWDGGDCSLSVGDPWRQCEA 1430
Score = 166 bits (420), Expect = 3e-40
Identities = 140/491 (28%), Positives = 206/491 (41%), Gaps = 103/491 (20%)
Query: 2321 CICPPGMARRPDGEGCVDENECRTKP----GICENGRCVNIIGSYRCECNEGFQSSSSGT 2376
C+CPPG GE C E+ C + P G+C++ V + C C GF+ G
Sbjct: 65 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSS-VVAGTARFSCRCPRGFR----GP 115
Query: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
+C L C S C G R C + ++
Sbjct: 116 DCS-----------LPDPCL-----------SSPCAHGAR--------CSVGPDGRFLCS 145
Query: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
CP G + D+DEC+V G C+NT GSFRC C GYT + + C+
Sbjct: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV---PCA 202
Query: 2497 QSPKPCNYICKNT-EGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGF 2554
SP C+ + + +Y C+C G+ +G+ C+ ++D+C + CV+ + +
Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258
Query: 2555 TCKCPPGFT-QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC- 2612
C+CPP +T Q T +D EC QP+ C G C NT G SC C G+ TG +C
Sbjct: 259 NCQCPPEWTGQFCTEDVD--ECQLQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCS 312
Query: 2613 EDVDECDGNHRCQHG--CQNILGGYRCGCPQ---GYIQHYQWNQCVDENECSNPNACGSA 2667
+++D+C C HG C + + + C CP G + H + CV N C C +
Sbjct: 313 QNIDDC-ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACV-SNPCHEDAICDTN 369
Query: 2668 SCYNTLGSYKCACPSGFSFDQFSSAC-HDVNECSSSKNPCNY--GCSNTEGGYLCGCPPG 2724
G C CP GF+ AC DV+ECS NPC + C NT+G +LC C G
Sbjct: 370 P---VNGRAICTCPPGFT----GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRG 422
Query: 2725 YY------------------------RVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE 2760
Y R+GQ C+ GF G Y +D + + +
Sbjct: 423 YTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCEVDIDECQSSPCVNG 481
Query: 2761 ACYECKINGYS 2771
+ ++NG+S
Sbjct: 482 GVCKDRVNGFS 492
Score = 38.5 bits (88), Expect = 0.098
Identities = 41/158 (25%), Positives = 54/158 (34%), Gaps = 33/158 (20%)
Query: 80 QDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPN---------MC 130
+D L+ P G F C G+ P + P C G RP+ C
Sbjct: 1220 RDCLQDP---GGGFRCLCHAGFSG-PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC 1275
Query: 131 TCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQKGYIGTYC-----GQPVCE 181
C+ C + ++C G C C C G G C P
Sbjct: 1276 HCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGAS 1335
Query: 182 NG------CQNGGRC----IGPN-RCACVYGFTGPQCE 208
N C +GG C + P RCAC G+TGP+CE
Sbjct: 1336 NASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 441 bits (1135), Expect = e-123
Identities = 308/998 (30%), Positives = 426/998 (42%), Gaps = 158/998 (15%)
Query: 1014 HPVPGKFRMDACCCAVGAAWG-TECEECP--------KPGTKEYETL--CPRGAGFANRG 1062
+P+PG + + CC ++G AWG ++C +CP KPG E CP+G N
Sbjct: 292 NPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNST 351
Query: 1063 DVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRIS 1122
+DINEC A PG+C +G C N GS++C C G +L C I +
Sbjct: 352 HC-------QDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC--IADKPEE 401
Query: 1123 PDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE-----CERNPLLCRGGTCVNT 1177
LC + S E +C + C + + C+R P GT
Sbjct: 402 KSLCFRLV------SPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPT---DGTAAFK 452
Query: 1178 EGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDR 1237
E C G+ + S + E S L +G S P + T +
Sbjct: 453 E---ICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEE 509
Query: 1238 QGCTD---IDECMIMNGGCDTQCTNSEGSYECSCSEGYAL--------MPDGRSCADI-- 1284
+G T + E + T T Y S +P RS +I
Sbjct: 510 RGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP 569
Query: 1285 ------DECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 1338
DEC N +IC G+C P +Y C C G+ + + C+DVNEC+
Sbjct: 570 TQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGR 629
Query: 1339 GECENTKGSFICHCQLGYSVKKGTTG--CTDVDECEIGAHNCDMHASCLNIPGSFKCSCR 1396
G C NT GS+ CHC GY + G G C D++EC H C C+N PG +KC+C
Sbjct: 630 GICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCY 688
Query: 1397 EGWIGNGIK---CIDLDECSNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGF-TCSDVD 1451
G+ + C D+DEC + + C + +C N PGS++C AC G+ G C DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPS-SCP-DGKCENKPGSFKCIACQPGYRSQGGGACRDVN 746
Query: 1452 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPG 1511
ECAE + C G C N+PG++RC C G+ PA D RSC D+DEC ++C G C+N PG
Sbjct: 747 ECAEG-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPG 805
Query: 1512 MFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLN------ 1565
F C C GY L R +C DIDEC P C+ G C+NT G Y C CP +L
Sbjct: 806 SFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 1566 -------------PTGV-----------------------GCVD----NRVGNCYLKFGP 1585
P G GC + + CYL F
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-- 923
Query: 1586 RGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET--CPPVNSTEYYTLCPGGEGFRPNP 1643
D ++ C++ + V++ CCCSLG WG+ CE CP +S E+++LCP G+G+ +
Sbjct: 924 --DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDN 981
Query: 1644 ITIIL-----EDIDECQELPG-LCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECF 1697
+ DIDEC +C+ G C+NT ++C C QG+Y + C D+DEC
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECL 1041
Query: 1698 AHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDM--------RKSFCY--RSYNGT 1747
C G C NT G Y C C P C+ R+ C+ R +G
Sbjct: 1042 DESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGM 1100
Query: 1748 TCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDI------ 1801
+T CCC G+ W C PCP G + +D
Sbjct: 1101 CAGPLAGPALTFDDCCCRQ--GRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLG 1158
Query: 1802 -----HTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS- 1855
D DEC+ C +G C+ + G CECP GF + C DIDEC
Sbjct: 1159 KPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRE 1213
Query: 1856 -NGDNLCQRNADCINSPGSYRCECAAGFKLS-PNGACV 1891
N L ++ C+N+ GS+RC C AGF S P+GACV
Sbjct: 1214 LNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 388 bits (996), Expect = e-107
Identities = 233/709 (32%), Positives = 325/709 (45%), Gaps = 93/709 (13%)
Query: 1105 ALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECER 1164
A+++ T+ DECR++ ++CG G CV P + C C GY S + C+D++ECE
Sbjct: 564 AVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRS-HPQHRYCVDVNECEA 622
Query: 1165 NPLLCRGGTCVNTEGSFQCDCPLGHEL--SPSREDCVDINECSLSDNLCRNGK-CVNMIG 1221
P G C+NT GS+ C C G+ L CVD+NEC+ +LC +G C+N G
Sbjct: 623 EPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPG 681
Query: 1222 TYQCSCNPGYQATPDRQG-CTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGR 1279
Y+C+C PGY+ R C DIDEC + D +C N GS++C +C GY G
Sbjct: 682 HYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG- 740
Query: 1280 SCADIDEC-ENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 1338
+C D++EC E +P C G C N+PG +RC C G+ + D ++C+DV+EC+ ++C
Sbjct: 741 ACRDVNECAEGSP--CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDN 797
Query: 1339 GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
G C NT GSF C C GY + + + C D+DEC+ A + C+N GS++C C +G
Sbjct: 798 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA--ACIGGDCINTNGSYRCLCPQG 855
Query: 1399 W-IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTG--DGFTCSDVD---- 1451
+ G KC D+DECS C + C N GSY C C EGFT D C +V+
Sbjct: 856 HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHH 915
Query: 1452 --ECAENIN---LCENGQCLNVPGAYRCECEMG--------------FTPASDSRSC--- 1489
EC N + C++ NV C C +G ++ A C
Sbjct: 916 KKECYLNFDDTVFCDSVLATNVT-QQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG 974
Query: 1490 -----------------QDIDECSF--QNICVFGTCNNLPGMFHCICDDGYELDRTGGNC 1530
+DIDEC IC G C N + C C G+ D C
Sbjct: 975 KGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLEC 1034
Query: 1531 TDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD--------NRVGNCYLK 1582
D+DEC D NC NG+C NT G Y C C P + +P C+ R C+
Sbjct: 1035 VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCW-- 1092
Query: 1583 FGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPP-----------VNSTEYYT 1631
RG+ + G ++ CCC G+ WG C CPP S ++
Sbjct: 1093 -SQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 1151
Query: 1632 LCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICE 1691
P G P ED DEC+ C G C+ G CECP G+ L C
Sbjct: 1152 TSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCV 1206
Query: 1692 DIDEC--FAHPG-VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRK 1737
DIDEC G +C C NT G++ C+C + + C+ R+
Sbjct: 1207 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255
Score = 345 bits (884), Expect = 5e-94
Identities = 237/737 (32%), Positives = 324/737 (43%), Gaps = 127/737 (17%)
Query: 1357 SVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSN 1414
+V+ T T+ DEC + + C H C+ P + C C G+ + C+D++EC
Sbjct: 564 AVEIAPTQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE- 621
Query: 1415 GTHQCSINAQ-CVNTPGSYRCACSEGFT----GDGFTCSDVDECAENINLCENGQCLNVP 1469
C C+NT GSY C C+ G+ G +C D++ECA+ + G C+N P
Sbjct: 622 -AEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP 680
Query: 1470 GAYRCECEMGFT-PASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCI-CDDGYELDRTG 1527
G Y+C C G+ AS C+DIDEC + C G C N PG F CI C GY + G
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGG 739
Query: 1528 GNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRG 1587
G C D++ECA+ C G C N PG + C C + P G C+D V C + G
Sbjct: 740 GACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD--VDEC--EAGDVC 795
Query: 1588 DGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITII 1647
D + NT C C G C
Sbjct: 796 DNGICSNTP-----GSFQCQCLSGYHLSRDRSHC-------------------------- 824
Query: 1648 LEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP-G 1706
EDIDEC + P C GG+CINT GS++C CPQG+ L R C+DIDEC P +C P G
Sbjct: 825 -EDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQDPSLCLPHG 881
Query: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMR----KSFCYRSYNGTT-CENELPFNVTKRM 1761
C N G+Y C+C + H C ++ K CY +++ T C++ L NVT++
Sbjct: 882 ACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQE 941
Query: 1762 CCCTYNVGKAWNKPCE--PCPTPGTADFKTICGNIPGFTFD---IHTGKAV--DIDECKE 1814
CCC+ +G W CE PCP +A+F ++C + G+T D ++ G DIDEC
Sbjct: 942 CCCS--LGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECML 999
Query: 1815 IPG-ICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGS 1873
IC G C+N + C C GF Y+ LL C D+DEC + N RN C N+ G
Sbjct: 1000 FGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC--RNGVCENTRGG 1057
Query: 1874 YRCECAAGFKLSP-NGACVDRNECLEIP---NVC-----SHGLCV-DLQGSY----QCIC 1919
YRC C + SP C+ E P +VC G+C L G C C
Sbjct: 1058 YRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCC 1117
Query: 1920 HNG------------------FKASQDQTMCM--------------------DVDECERH 1941
G SQ ++ D DEC
Sbjct: 1118 RQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-- 1175
Query: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDECSSF--FGQVCRNGRCFNEIGSFK 1998
C +G C G C C GF+L + C+DIDEC G +C++ RC N GSF+
Sbjct: 1176 -CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFR 1234
Query: 1999 CLCNEGYELTPDGKNCI 2015
C+C G+ + C+
Sbjct: 1235 CVCKAGFARSRPHGACV 1251
Score = 344 bits (882), Expect = 8e-94
Identities = 228/727 (31%), Positives = 319/727 (43%), Gaps = 99/727 (13%)
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCT 2073
+T+EC C G C + C C PGY ++ C+D+NEC+ +P G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 2074 NTPGGFQCLCPPGFVL--SDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
NT G + C C G+ L GR C D + C+ P C
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNE-----------CAKPHLCGDGGF---CINF 679
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
PG ++ C G+ S ED++EC + P C +G+C N
Sbjct: 680 PGH----------------YKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKP 722
Query: 2192 GSFRC-ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPM-M 2249
GSF+C C GY G C D +EC+ G+PC G C N+ GSF C C +G+ P P
Sbjct: 723 GSFKCIACQPGYRSQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 781
Query: 2250 NCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRG 2309
+C D++EC + C NT GS++C C GY L D+ C+D+DEC G
Sbjct: 782 SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD---FPAACIG 838
Query: 2310 MMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRCECNEG 2368
C N G++ C+CP G R G C D +EC P +C +G C N+ GSY C C+EG
Sbjct: 839 GDCINTNGSYRCLCPQGH-RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 2369 FQSSSSGTECLDNRQGL----CFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCEL 2424
F + C + Q C+ T+ + + N VT+ ECCC G GWG CE+
Sbjct: 898 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN-VTQQECCCSLGAGWGDHCEI 956
Query: 2425 --CPLPGTAQYKKICPHGPGYTTDG----------RDIDECKVMPN-LCTNGQCINTMGS 2471
CP+ +A++ +CP G GYT D RDIDEC + + +C G+C+NT
Sbjct: 957 YPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPG 1016
Query: 2472 FRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK 2531
+ C+CK G+ D + C+D+DEC N +C+NT G Y+C+C + C
Sbjct: 1017 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCL 1076
Query: 2532 DLDECQT---------KQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLC 2582
+E + Q +C L G P T C G+Q C
Sbjct: 1077 SPEEMERAPERRDVCWSQRGEDGMCAGPLAG------PALTFDDCCCRQGRGWGAQCRPC 1130
Query: 2583 GAKGICQNTPGSFSCECQRGFSLDATGL-----------NCEDVDECDGNHRCQHG-CQN 2630
+G + P S S + D + L + ED DEC RC G C
Sbjct: 1131 PPRGAGSHCPTSQS---ESNSFWDTSPLLLGKPPRDEDSSEEDSDEC----RCVSGRCVP 1183
Query: 2631 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPN----ACGSASCYNTLGSYKCACPSGFSF 2686
GG C CP G+ +CVD +EC N C S C NT GS++C C +GF+
Sbjct: 1184 RPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFAR 1243
Query: 2687 DQFSSAC 2693
+ AC
Sbjct: 1244 SRPHGAC 1250
Score = 334 bits (856), Expect = 9e-91
Identities = 217/698 (31%), Positives = 299/698 (42%), Gaps = 122/698 (17%)
Query: 1800 DIHTGKAVDIDECKEIPGICAN-------------------------------------- 1821
+I + + DEC+ IC +
Sbjct: 566 EIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPC 625
Query: 1822 ----GVCINQIGSFRCECPTGFSYNDLL--LVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
G+C+N GS+ C C G+ + C D++EC+ +LC CIN PG Y+
Sbjct: 626 GPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYK 684
Query: 1876 CECAAGFKL--SPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI-CHNGFKASQDQTMC 1932
C C G++L S C D +EC + P+ C G C + GS++CI C G++ SQ C
Sbjct: 685 CNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYR-SQGGGAC 742
Query: 1933 MDVDEC-ERHPCGNGTCKNTVGSYNCLCYPGF-ELTHNNDCLDIDECSSFFGQVCRNGRC 1990
DV+EC E PC G C+N GS+ C C G+ CLD+DEC + G VC NG C
Sbjct: 743 RDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGIC 800
Query: 1991 FNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE-V 2049
N GSF+C C GY L+ D +C D +EC P +C G C N GS+RC+CP G+ V
Sbjct: 801 SNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRLV 859
Query: 2050 KSENCIDINECDEDPNICL-FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSF----C 2104
C DI+EC +DP++CL G+C N G + C+C GF + + C + Q C
Sbjct: 860 GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Query: 2105 FTNFENGK-CSVPKAFNTTKAKCCCSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGT 2161
+ NF++ C A N T+ +CCCS G GWGD CE+ CP F LCP G G
Sbjct: 920 YLNFDDTVFCDSVLATNVTQQECCCSL--GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGY 977
Query: 2162 VPSLH------DTREDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
+ D++EC L IC G+C+NT + C C G+ D + CVD
Sbjct: 978 TQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDV 1037
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQNPL----------- 2262
DEC + C NG C N G + C C E P C E + P
Sbjct: 1038 DECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGE 1097
Query: 2263 --LCAFRCMNTFGSY-ECTCPIGYALREDQKMC--------------------------- 2292
+CA ++ +C C G + C
Sbjct: 1098 DGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLL 1157
Query: 2293 ----KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR---TK 2345
+D D E +C C G +C CP G CVD +ECR +
Sbjct: 1158 GKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQR 1217
Query: 2346 PGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2383
+C++ RCVN GS+RC C GF S C+ R+
Sbjct: 1218 GLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255
Score = 296 bits (758), Expect = 2e-79
Identities = 216/724 (29%), Positives = 296/724 (40%), Gaps = 171/724 (23%)
Query: 1892 DRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCG--NGTCK 1949
+ +EC N+C HG CV Y C C+ G+++ C+DV+ECE PCG G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1950 NTVGSYNCLCYPGFEL---THNNDCLDIDECSSFFGQVCRNGR-CFNEIGSFKCLCNEGY 2005
NT GSYNC C G+ L C+D++EC+ +C +G C N G +KC C GY
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK--PHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 2006 ELTPDGKN-CIDTNECVALPGSCSPGTCQNLEGSFRCI-CPPGYEVKSEN-CIDINECDE 2062
L C D +EC P SC G C+N GSF+CI C PGY + C D+NEC E
Sbjct: 692 RLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAE 750
Query: 2063 DPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTT 2122
+ C G C N PG F+C C G+ + +GR C D + +NG
Sbjct: 751 G-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG----------- 798
Query: 2123 KAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTR-----EDVNECLE 2177
CS PG +FQ C G+ H +R ED++EC +
Sbjct: 799 ----ICSNTPG----------------SFQCQCLSGY------HLSRDRSHCEDIDEC-D 831
Query: 2178 SPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC--GNGTCTNVIGSF 2235
P C G CINT+GS+RC CP G+ L G +C D DECS +G C N+ GS+
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2236 ECNCNEGFEPGPMMN-CEDIN------ECAQN---PLLCAFRCMNTFGSYECTCPIG--- 2282
C C+EGF P + CE++ EC N + C EC C +G
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2283 -----------YALREDQKMC--------------------KDLDECAE-GLHDCESRGM 2310
Y+ E +C +D+DEC G C+
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-- 1008
Query: 2311 MCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2370
C N + C C G + CVD +EC + C NG C N G YRC C +
Sbjct: 1009 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAE 1067
Query: 2371 SSSSGTECLD--------NRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQC 2422
S + +CL R+ +C+++ + + +T +CCC GRGWG QC
Sbjct: 1068 YSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQC 1127
Query: 2423 ELCPLPGTAQY------------------------------------------------K 2434
CP G +
Sbjct: 1128 RPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGG 1187
Query: 2435 KICPHGPGYTTDGR-----DIDECKVMPN---LCTNGQCINTMGSFRCFCKVGYTTDISG 2486
+C G+ D DIDEC+ + LC + +C+NT GSFRC CK G+
Sbjct: 1188 AVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPH 1247
Query: 2487 TSCI 2490
+C+
Sbjct: 1248 GACV 1251
Score = 291 bits (744), Expect = 8e-78
Identities = 216/734 (29%), Positives = 299/734 (40%), Gaps = 186/734 (25%)
Query: 1930 TMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCR 1986
T + DEC ++ CG+G C Y+C C PG+ + C+D++EC + + C
Sbjct: 570 TQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA---EPCG 626
Query: 1987 NGR--CFNEIGSFKCLCNEGYELT--PDGKNCIDTNECVALPGSCSPGT-CQNLEGSFRC 2041
GR C N GS+ C CN GY L G++C+D NEC A P C G C N G ++C
Sbjct: 627 PGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKC 685
Query: 2042 ICPPGYEVKSEN---CIDINECDEDPNICLFGSCTNTPGGFQCL-CPPGFVLSDNGRRCF 2097
C PGY +K+ C DI+EC DP+ C G C N PG F+C+ C PG+ S G C
Sbjct: 686 NCYPGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGY-RSQGGGACR 743
Query: 2098 DTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPY 2157
D + E CS GW CE P +F+ C
Sbjct: 744 DVNECA-----EGSPCS-------------------PGW---CENLPG----SFRCTCAQ 772
Query: 2158 GHGTVPSLHDTRE--DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTD 2215
G+ P D R DV+EC E+ +C NG C NT GSF+C+C GY+L C D D
Sbjct: 773 GYAPAP---DGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDID 828
Query: 2216 ECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCA--FRCMNTFG 2273
EC C G C N GS+ C C +G C+DI+EC+Q+P LC C N G
Sbjct: 829 ECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQG 888
Query: 2274 SYECTCPIGYALREDQKMCKDLD------ECAEGLHDCESRGMMCKNLIGTFM----CIC 2323
SY C C G+ +DQ C++++ EC D + C +++ T + C C
Sbjct: 889 SYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT----VFCDSVLATNVTQQECCC 944
Query: 2324 PPGM--------------------ARRPDGEGCVDEN--------------ECRT-KPGI 2348
G + PDG+G +N EC I
Sbjct: 945 SLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI 1004
Query: 2349 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC------------- 2395
C+ G+CVN Y C C +GF + EC+D + L + +C
Sbjct: 1005 CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTP 1064
Query: 2396 -----------------QMASSSRNL-------------------VTKSECCCDGGRGWG 2419
+ A R++ +T +CCC GRGWG
Sbjct: 1065 PAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWG 1124
Query: 2420 HQCELCPLPGTAQYKKICPHGPGYT-------------------TDGRDIDECKVMPNLC 2460
QC CP G + CP + + D DEC+ C
Sbjct: 1125 AQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----C 1176
Query: 2461 TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC---SQSPKPC-NYICKNTEGSYQCS 2516
+G+C+ G C C G+ D S C+D+DEC +Q C + C NT GS++C
Sbjct: 1177 VSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1236
Query: 2517 CPRGYVLQEDGKTC 2530
C G+ C
Sbjct: 1237 CKAGFARSRPHGAC 1250
Score = 288 bits (737), Expect = 5e-77
Identities = 213/715 (29%), Positives = 292/715 (40%), Gaps = 168/715 (23%)
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGT-- 1707
+ DEC+ +C G C+ + C C GY R C D++EC A P CGPG
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGPGRGI 631
Query: 1708 CYNTLGNYTCICPPEY-MQVN-GGHNCMDMRKSFCYRSY---NGTTCENELPFNVTKRMC 1762
C NT G+Y C C Y + V GG +C+D+ + C + + +G C N P + K C
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNE--CAKPHLCGDGGFCIN-FPGHY-KCNC 687
Query: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANG 1822
Y + + CE DIDEC++ P C +G
Sbjct: 688 YPGYRLKASRPPVCE------------------------------DIDECRD-PSSCPDG 716
Query: 1823 VCINQIGSFRC-ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAG 1881
C N+ GSF+C C G+ C D++EC+ G C N PGS+RC CA G
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGG-ACRDVNECAEGSPCSP--GWCENLPGSFRCTCAQG 773
Query: 1882 FKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE- 1939
+ +P+G +C+D +EC E +VC +G+C + GS+QC C +G+ S+D++ C D+DEC+
Sbjct: 774 YAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF 832
Query: 1940 RHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKC 1999
C G C NT GSY CLC G L C DIDECS +G C N GS+ C
Sbjct: 833 PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVC 892
Query: 2000 LCNEGYELTPDGKNC-----------------------------IDTNECVALPGSCSPG 2030
+C+EG+ T D C + EC G+
Sbjct: 893 VCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGD 952
Query: 2031 TCQ------NLEGSFRCICPPGYEVKSENCI---------DINECD-EDPNICLFGSCTN 2074
C+ F +CP G +N I DI+EC IC G C N
Sbjct: 953 HCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVN 1012
Query: 2075 TPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENG-----------KCSVPKAFNTTK 2123
T G++C C GF N C D + +N NG C+ P ++ +
Sbjct: 1013 TQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQ 1072
Query: 2124 AKC---------------------------------------CCSKMPGEGWGDPCELCP 2144
+C CC + G GWG C CP
Sbjct: 1073 RQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQ-GRGWGAQCRPCP 1131
Query: 2145 -----------KDDEVAFQDLCPYGHGTVPSLHD-TREDVNECLESPGICSNGQCINTDG 2192
+ + +F D P G P D + ED +EC C +G+C+ G
Sbjct: 1132 PRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPG 1186
Query: 2193 SFRCECPMGYNLDYTGVRCVDTDEC----SIGNPCGNGTCTNVIGSFECNCNEGF 2243
CECP G+ LD + RCVD DEC G C + C N GSF C C GF
Sbjct: 1187 GAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Score = 285 bits (729), Expect = 5e-76
Identities = 186/590 (31%), Positives = 255/590 (43%), Gaps = 120/590 (20%)
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRC-ECNMGYKQDANGDCIDVDECTS-NPCTNGDCV 550
+ ID C+ ++ C +G+C S++C C GY+ G C DV+EC +PC+ G C
Sbjct: 702 EDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCE 760
Query: 551 NTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTT 610
N PGS+ C C G+ P ++C+D+DEC + G +C NG C NT GSFQC C +G+ L+
Sbjct: 761 NLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSR 819
Query: 611 DGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC-QTPGICM 669
D +C D DEC C+ G CIN +GS++C+C G L GR C D+DEC Q P +C+
Sbjct: 820 DRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPSLCL 878
Query: 670 -NGHCINSEGSFRCDCPPGLAVGMDGRVCVDT---HMRSTCYGGIKKGV-CVRPFPGAVT 724
+G C N +GS+ C C G D C + H + CY V C VT
Sbjct: 879 PHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT 938
Query: 725 KSECCCANPDYGFGEPCQ--PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANG 782
+ ECCC+ G+G+ C+ PCP +SAEFH LC G G T D +N G
Sbjct: 939 QQECCCSL-GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY----------G 987
Query: 783 ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLV-NRLLCDNGLCRNTPGSYSCTCPPGY 841
I + DIDEC++ +C G C NT Y C C G+
Sbjct: 988 IPAHR----------------------DIDECMLFGSEICKEGKCVNTQPGYECYCKQGF 1025
Query: 842 VFRTETETCEDINEC--ESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICID------- 892
+ C D++EC ESN C NG C N G + C C+P ++ S C+
Sbjct: 1026 YYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERA 1084
Query: 893 -SLKGTCWLNI-QDSRCEVNINGATLK-SECCATLGAAWGSPCERCELDTA---CP---- 942
+ CW +D C + G L +CC G WG+ C C A CP
Sbjct: 1085 PERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQS 1144
Query: 943 -----------------------------------RGLARIKGVTCE------------- 954
R + R G CE
Sbjct: 1145 ESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRAR 1204
Query: 955 --DVNECEVFPG---VCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 999
D++EC +C + RCVN+ GSF C C G C+ R
Sbjct: 1205 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
Score = 276 bits (706), Expect = 2e-73
Identities = 209/711 (29%), Positives = 295/711 (41%), Gaps = 145/711 (20%)
Query: 943 RGLARIKGVTCEDVNECEVFPGVCPNGRCV------------------------------ 972
R I + +EC + +C +G CV
Sbjct: 562 RSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE 621
Query: 973 ------------NSKGSFHCECPEG--LTLDGTGRVCLDI-RMEQCYLKWDEDECIHPVP 1017
N+ GS++C C G L + GR C+D+ + +L D CI+ P
Sbjct: 622 AEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCIN-FP 680
Query: 1018 GKFRMDACCCAVG----AAWGTECE---ECPKPGTKEYETLCPRGAGFANRGD--VLTGR 1068
G ++ C C G A+ CE EC P + CP G G + +
Sbjct: 681 GHYK---CNCYPGYRLKASRPPVCEDIDECRDPSS------CPDGKCENKPGSFKCIACQ 731
Query: 1069 PFY--------KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR 1120
P Y +D+NEC A C+ G C N GSF+C C G+A + R+C D+DEC
Sbjct: 732 PGYRSQGGGACRDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECE 790
Query: 1121 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGS 1180
+ D+C +GIC NTPGSF+C+C GY +C DIDEC+ P C GG C+NT GS
Sbjct: 791 -AGDVCDNGICSNTPGSFQCQCLSGYHLS-RDRSHCEDIDECD-FPAACIGGDCINTNGS 847
Query: 1181 FQCDCPLGHELSPSREDCVDINECSLSDNLC-RNGKCVNMIGTYQCSCNPGYQATPDRQG 1239
++C CP GH L R+ C DI+ECS +LC +G C N+ G+Y C C+ G+ T D+ G
Sbjct: 848 YRCLCPQGHRLVGGRK-CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHG 906
Query: 1240 CTDID------ECMIMNGG---CDTQCTNSEGSYECSCSEG------------------- 1271
C +++ EC + CD+ + EC CS G
Sbjct: 907 CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE 966
Query: 1272 -YALMPDGRSCA--------------DIDECE-NNPDICDGGQCTNIPGEYRCLCYDGFM 1315
++L PDG+ DIDEC +IC G+C N Y C C GF
Sbjct: 967 FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFY 1026
Query: 1316 ASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGA 1375
++ C+DV+EC L+ + C G CENT+G + C C C +E E
Sbjct: 1027 YDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAP 1085
Query: 1376 HNCDMHASCLNIPGSF------------KCSCREGWIGNGIKCIDLDECSNGTHQCSINA 1423
D+ S G C CR+G G G +C G+H + +
Sbjct: 1086 ERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG-RGWGAQCRPCPPRGAGSHCPTSQS 1144
Query: 1424 QCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPA 1483
+ + + + + + D DEC C +G+C+ PG CEC GF
Sbjct: 1145 ESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLD 1199
Query: 1484 SDSRSCQDIDECSFQN----ICVFGTCNNLPGMFHCICDDGYELDRTGGNC 1530
+ C DIDEC N +C C N G F C+C G+ R G C
Sbjct: 1200 ASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
Score = 245 bits (625), Expect = 5e-64
Identities = 203/731 (27%), Positives = 279/731 (38%), Gaps = 162/731 (22%)
Query: 768 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 827
+ +EC L+ +IC +G C Y C+CN GY R C+D++EC G+C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 828 NTPGSYSCTCPPGYVFRTET--ETCEDINEC-ESNPCVNGA-CRNNLGSFNCECSPGSKL 883
NT GSY+C C GY +C D+NEC + + C +G C N G + C C PG +L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 884 -SSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACP 942
+S +C D + + D +CE N G+ +C AC
Sbjct: 694 KASRPPVCEDIDECRDPSSCPDGKCE-NKPGSF------------------KC---IACQ 731
Query: 943 RGLARIKGVTCEDVNEC-EVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
G G C DVNEC E P C G C N GSF C C +G GR CLD+
Sbjct: 732 PGYRSQGGGACRDVNECAEGSP--CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC 789
Query: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR 1061
+ D C + PG F+ C C G + C
Sbjct: 790 EAGDVCDNGICSN-TPGSFQ---CQCLSGYHLSRDRSHC--------------------- 824
Query: 1062 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRI 1121
+DI+EC FP C G C NT GS++C C G L + R C DIDEC
Sbjct: 825 ----------EDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQ 872
Query: 1122 SPDLC-GSGICVNTPGSFECECFEGYESGFMMMKNCMDID------ECERN---PLLCRG 1171
P LC G C N GS+ C C EG+ + C +++ EC N + C
Sbjct: 873 DPSLCLPHGACKNLQGSYVCVCDEGF-TPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDS 931
Query: 1172 GTCVNTEGSFQCDCPLG--------------------HELSPSREDCV------------ 1199
N +C C LG H L P +
Sbjct: 932 VLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA 990
Query: 1200 --DINECSL-SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
DI+EC L +C+ GKCVN Y+C C G+ + C D+DEC+ + +
Sbjct: 991 HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGV 1050
Query: 1257 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNP---DIC-----DGGQCTN-IPGEY- 1306
C N+ G Y C+C+ P R C +E E P D+C + G C + G
Sbjct: 1051 CENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPAL 1110
Query: 1307 ---RCLCYDGFMASMDMKTC---------------------------------IDVNECD 1330
C C G + C D +E D
Sbjct: 1111 TFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEED 1170
Query: 1331 LNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC-EIGAHNCDMHAS-CLNIP 1388
+ C+ G C G +C C G+ + C D+DEC E+ + C+N
Sbjct: 1171 SDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTS 1230
Query: 1389 GSFKCSCREGW 1399
GSF+C C+ G+
Sbjct: 1231 GSFRCVCKAGF 1241
Score = 240 bits (613), Expect = 1e-62
Identities = 171/539 (31%), Positives = 219/539 (40%), Gaps = 91/539 (16%)
Query: 2253 DINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM 2311
+ +EC N +C C+ Y C C GY + C D++EC C +
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA--EPCGPGRGI 631
Query: 2312 CKNLIGTFMCICPPGMARR--PDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRCECNEG 2368
C N G++ C C G G CVD NEC KP +C + G C+N G Y+C C G
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 2369 FQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLP 2428
++ +S +C+ R+ C DG +CE P
Sbjct: 691 YRLKASRPP----------------VCEDIDECRD----PSSCPDG------KCENKP-- 722
Query: 2429 GTAQYKKICPHGPGYTTDG----RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDI 2484
+K I PGY + G RD++EC + C+ G C N GSFRC C GY
Sbjct: 723 --GSFKCIACQ-PGYRSQGGGACRDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAP 778
Query: 2485 SGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ 2544
G SC+D+DEC N IC NT GS+QC C GY L D C+D+DEC
Sbjct: 779 DGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG 838
Query: 2545 FLCVNTLGGFTCKCPPGFTQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGF 2603
C+NT G + C CP G C D +EC PSLC G C+N GS+ C C GF
Sbjct: 839 GDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGF 898
Query: 2604 SLDATGLNCEDVDECDGNHRC-------------------QHGCQNILGG--------YR 2636
+ CE+V++ C Q C LG Y
Sbjct: 899 TPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYP 958
Query: 2637 CG----------CP--QGYIQ-----HYQWNQCVDENECS--NPNACGSASCYNTLGSYK 2677
C CP +GY Q +Y D +EC C C NT Y+
Sbjct: 959 CPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYE 1018
Query: 2678 CACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGC-PPGYYRVGQGHCVS 2735
C C GF +D C DV+EC N N C NT GGY C C PP Y Q C+S
Sbjct: 1019 CYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLS 1077
Score = 236 bits (602), Expect = 2e-61
Identities = 174/591 (29%), Positives = 245/591 (41%), Gaps = 57/591 (9%)
Query: 2179 PGICSNGQCINTDGSF--RCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFE 2236
PG+ C + G+ + +C L YTGV+ V G
Sbjct: 295 PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP----------------VRGEVG 338
Query: 2237 CNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC-KDL 2295
+C +G++ +C+DINECA + C+N GSY C CP G++L + C D
Sbjct: 339 ADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 2296 DECAEGLHDCESRGMMCKNLIGTFM----CICPPGMARRPDGEGCVDENECRTKPGICEN 2351
E S C++ + T + C C G A + C + K IC
Sbjct: 399 PEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE-ICPA 457
Query: 2352 GRCVNIIGSYRCECNEGFQSSSS--GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSE 2409
G+ +I+ S++ +G S + Q L + + R + T S
Sbjct: 458 GKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSP 517
Query: 2410 CCCDGGRGWGHQC----------ELCPLPGTAQYKKICPHGPGYT-------TDGRDIDE 2452
+ H EL P + P P T + DE
Sbjct: 518 VSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDE 577
Query: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP-KPCNYICKNTEG 2511
C++ N+C +G+C+ + C C GY + C+D++EC P P IC NT G
Sbjct: 578 CRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG 637
Query: 2512 SYQCSCPRGYVLQ--EDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPGF---TQ 2564
SY C C RGY L G++C DL+EC K H C C+N G + C C PG+
Sbjct: 638 SYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPGYRLKAS 696
Query: 2565 HHTACIDNNECGSQPSLCGAKGICQNTPGSFSC-ECQRGFSLDATGLNCEDVDECDGNHR 2623
C D +EC PS C G C+N PGSF C CQ G+ G C DV+EC
Sbjct: 697 RPPVCEDIDEC-RDPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEGSP 753
Query: 2624 CQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPS 2682
C G C+N+ G +RC C QGY C+D +EC + C + C NT GS++C C S
Sbjct: 754 CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLS 813
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHC 2733
G+ + S C D++EC C NT G Y C CP G+ VG C
Sbjct: 814 GYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKC 864
Score = 230 bits (586), Expect = 2e-59
Identities = 206/737 (27%), Positives = 280/737 (37%), Gaps = 153/737 (20%)
Query: 181 ENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQ-VNNQMCQGQLTGIVCTKTLC 239
+N C +G GP +C C YR+ P V+ C+ + G + +C
Sbjct: 582 QNICGHGECVPGPPDYSC-------HCNPGYRSHPQHRYCVDVNECEAEPCGP--GRGIC 632
Query: 240 CATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTG--ACQDVDECQAIPGIC-QGGNCINTV 296
T G H C RG+ ++ G +C D++EC A P +C GG CIN
Sbjct: 633 MNTGGSYNCH-----------CNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFP 680
Query: 297 GSFECRCPAGHK-QSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV-CPRGYVTSTD 354
G ++C C G++ ++ CEDIDEC P C G+C N GS+ C+ C GY S
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGY-RSQG 738
Query: 355 GSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYR 414
G C D VN CA+ P C PG C
Sbjct: 739 GGACRD----------VN-ECAEGSP---------CSPGWC------------------- 759
Query: 415 RLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGA 474
+PGS T G+AP+ +G NG G+
Sbjct: 760 ---------ENLPGSFRC----TCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGS 806
Query: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCI 534
G ++ + ID C A C+ G CI T SYRC C G++ C
Sbjct: 807 FQCQCLSGYHLSRDRSHCEDIDECDFPA-ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 535 DVDECTSNPCT---NGDCVNTPGSYYCKCHAGFQRTPTKQACIDID------ECIQN--- 582
D+DEC+ +P +G C N GSY C C GF T + C +++ EC N
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDD 925
Query: 583 GVLCKNGRCVNTDGSFQCICNAG--------------------FELTTDGKNCV------ 616
V C + N +C C+ G L DGK
Sbjct: 926 TVFCDSVLATNVTQQ-ECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIV 984
Query: 617 --------DHDECTT--TNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPG 666
D DEC + +C G C+N ++C CK GF N C DVDEC
Sbjct: 985 NYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 1044
Query: 667 ICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD-------THMRSTCYGGI-KKGVCVRP 718
C NG C N+ G +RC C P R C+ R C+ + G+C P
Sbjct: 1045 NCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGP 1104
Query: 719 FPGAVTKSECCCANPDYGFGEPCQPCPAK-----------NSAEFHGLCSSGVGITVDGR 767
G + CC G+G C+PCP + S F +G
Sbjct: 1105 LAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDE 1164
Query: 768 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL-VNR--LLCDNG 824
D +E D C +G C G C C G++ DAS C+DIDEC +N+ LLC +
Sbjct: 1165 DSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1224
Query: 825 LCRNTPGSYSCTCPPGY 841
C NT GS+ C C G+
Sbjct: 1225 RCVNTSGSFRCVCKAGF 1241
Score = 208 bits (529), Expect = 7e-53
Identities = 207/807 (25%), Positives = 291/807 (36%), Gaps = 211/807 (26%)
Query: 26 TAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLR- 84
T +P P RP PP + + P+ +AV + + D R
Sbjct: 532 TTTPARPYPELISRPSPPTMR-----------WFLPDLPPSRSAVEIAPTQVTETDECRL 580
Query: 85 GPNVCGSR--------FHSYCCPGWKTLPGGNQCI-VPICR-NSCGDG--FCSRPN---M 129
N+CG + +C PG+++ P C+ V C CG G C
Sbjct: 581 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 130 CTCSSG-QISSTCGSKS---IQQCSVR--CMNGGTCADD----HCQCQKGYIGTYCGQPV 179
C C+ G ++ G +S + +C+ C +GG C + C C GY PV
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 180 CEN-------------GCQN------------------GGRCIGPNRCA----CVYGFTG 204
CE+ C+N GG C N CA C G+
Sbjct: 701 CEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCE 760
Query: 205 P-------QCERDYRTGPCFTQ-VNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPA 256
C + Y P ++ C+ G VC +C T G C+
Sbjct: 761 NLPGSFRCTCAQGYAPAPDGRSCLDVDECE---AGDVCDNGICSNTPG---SFQCQ---- 810
Query: 257 QPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC 316
C G+ + C+D+DEC P C GG+CINT GS+ C CP GH+ +KC
Sbjct: 811 ----CLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHR-LVGGRKC 864
Query: 317 EDIDECSIIPGIC-ETGECSNTVGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSGLV 371
+DIDECS P +C G C N GSY CVC G+ + D C + C+
Sbjct: 865 QDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD 924
Query: 372 NG-RCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSA 430
+ C L +T+ +CCC G WG CPV S E+ LC D
Sbjct: 925 DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPD----------- 973
Query: 431 GSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTI 490
G G+ N YG IP
Sbjct: 974 --------GKGYTQDNNIVNYG--------IPA--------------------------- 990
Query: 491 LNQTIDICK-HHANLCLNGRCIPTVSSYRCECNMGYKQDAN-GDCIDVDEC-TSNPCTNG 547
++ ID C + +C G+C+ T Y C C G+ D N +C+DVDEC + C NG
Sbjct: 991 -HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG 1049
Query: 548 DCVNTPGSYYCKCHAGFQRTPTKQACI---DIDECIQNGVLC-----KNGRCVNTDGS-- 597
C NT G Y C C + +P ++ C+ +++ + +C ++G C
Sbjct: 1050 VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPA 1109
Query: 598 ---FQCIC----------------NAGFELTTD---------------GKNCVDHD---E 620
C C AG T GK D D E
Sbjct: 1110 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEE 1169
Query: 621 CTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC----QTPGICMNGHCINS 676
+ C++G C+ G C C GF L + C D+DEC Q +C + C+N+
Sbjct: 1170 DSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNT 1229
Query: 677 EGSFRCDCPPGLAVGMDGRVCVDTHMR 703
GSFRC C G A CV R
Sbjct: 1230 SGSFRCVCKAGFARSRPHGACVPQRRR 1256
Score = 130 bits (328), Expect = 1e-29
Identities = 60/167 (35%), Positives = 90/167 (53%), Gaps = 22/167 (13%)
Query: 913 GATLKSECCATLGAAWG-SPCERC----------------ELDTACPRGLARIKGVTCED 955
G T + +CC ++G AWG S C +C E+ CP+G R+ C+D
Sbjct: 296 GLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQD 355
Query: 956 VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQ---CY-LKWDEDE 1011
+NEC + PGVC +G C+N+ GS+ C CP G +L + C+ + E+ C+ L E +
Sbjct: 356 INECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQ 414
Query: 1012 CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
C HP+ + CCC+VG AWG C+ CP GT ++ +CP G G+
Sbjct: 415 CQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGY 461
Score = 97.4 bits (241), Expect = 2e-19
Identities = 59/188 (31%), Positives = 87/188 (46%), Gaps = 38/188 (20%)
Query: 239 CCATIGRAWGHP-CEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVG 297
CC +IG AWG C CP G+ + G VG
Sbjct: 303 CCGSIGTAWGQSKCHKCPQLQYT------------------------GVQKPGPVRGEVG 338
Query: 298 SFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSR 357
+ CP G+K+ +T C+DI+EC++ PG+C G+C N GSY CVCP G+ ++
Sbjct: 339 A---DCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 358 CI---DQRTGMCFSGLVN--GRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEE 412
CI + +CF LV+ +C L R+T+ CCC G+ WG + CP G+
Sbjct: 394 CIADKPEEKSLCFR-LVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARC--QRCPTDGTAA 450
Query: 413 YRRLCMDG 420
++ +C G
Sbjct: 451 FKEICPAG 458
Score = 88.2 bits (217), Expect = 1e-16
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 13/138 (9%)
Query: 652 NGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV--DTHMRSTCYGG 709
N +C D++EC PG+C +G C+N+ GS+RC CPPG ++G C+ +S C+
Sbjct: 349 NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRL 408
Query: 710 IK-KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVG------- 761
+ + C P +T+ CCC + +G CQ CP +A F +C +G G
Sbjct: 409 VSPEHQCQHPLTTRLTRQLCCC-SVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSH 467
Query: 762 --ITVDGRDINECALDPD 777
+T+ G L PD
Sbjct: 468 QTLTIQGESDFSLFLHPD 485
Score = 83.6 bits (205), Expect = 3e-15
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 40/160 (25%)
Query: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINEC 2060
C +GY+ + +C D NEC A+PG C G C N GS+RC+CPPG+ + I +
Sbjct: 341 CPQGYKRL-NSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 2061 DEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN 2120
E+ ++C F+ + P +C P
Sbjct: 399 PEEKSLC-----------FRLVSP-------------------------EHQCQHPLTTR 422
Query: 2121 TTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2160
T+ CCCS G+ WG C+ CP D AF+++CP G G
Sbjct: 423 LTRQLCCCS--VGKAWGARCQRCPTDGTAAFKEICPAGKG 460
Score = 75.9 bits (185), Expect = 6e-13
Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 831 GSYSCTCPPGYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLI 889
G CP GY R + C+DINEC C +G C NN GS+ C C PG L +
Sbjct: 335 GEVGADCPQGYK-RLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 890 CI---DSLKGTCW-LNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELD------T 939
CI K C+ L + +C+ + + CC ++G AWG+ C+RC D
Sbjct: 394 CIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE 453
Query: 940 ACPRG 944
CP G
Sbjct: 454 ICPAG 458
Score = 66.2 bits (160), Expect = 4e-10
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 12/122 (9%)
Query: 1087 GKC-RNTIGSFKCRCNSGFALDMEERNCTDI------DECRISPDLCGSGICVNTP--GS 1137
G+C ++T+ C N L +E C I +C P L +G+ P G
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 1138 FECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED 1197
+C +GY+ + +C DI+EC P +CR G C+N GS++C CP GH L PSR
Sbjct: 337 VGADCPQGYKR--LNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1198 CV 1199
C+
Sbjct: 394 CI 395
Score = 64.3 bits (155), Expect = 2e-09
Identities = 44/151 (29%), Positives = 65/151 (43%), Gaps = 25/151 (16%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGH-QCELCPLPGTAQYKKICPHGP- 2441
G CF + L ++ L + +CC G WG +C CP QY + GP
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCP---QLQYTGVQKPGPV 333
Query: 2442 ----------GY----TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGT 2487
GY +T +DI+EC MP +C +G C+N GS+RC C G++ S T
Sbjct: 334 RGEVGADCPQGYKRLNSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2488 SCIDLDECSQSPKPCNYICKNTEGSYQCSCP 2518
CI + P+ + + +QC P
Sbjct: 393 QCI-----ADKPEEKSLCFRLVSPEHQCQHP 418
Score = 59.7 bits (143), Expect = 4e-08
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 25/129 (19%)
Query: 1774 KPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIP-----GICANGVCINQI 1828
+PC P PG + CG+I G A +C + P G+ G ++
Sbjct: 287 QPCGSNPLPGLTKQEDCCGSI---------GTAWGQSKCHKCPQLQYTGVQKPGPVRGEV 337
Query: 1829 GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG 1888
G+ +CP G+ + C+DI+EC+ +C R+ DC+N+PGSYRC C G L P+
Sbjct: 338 GA---DCPQGYKRLNSTH-CQDINECAM-PGVC-RHGDCLNNPGSYRCVCPPGHSLGPS- 390
Query: 1889 ACVDRNECL 1897
R +C+
Sbjct: 391 ----RTQCI 395
Score = 55.1 bits (131), Expect = 1e-06
Identities = 52/238 (21%), Positives = 84/238 (35%), Gaps = 46/238 (19%)
Query: 2631 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFS 2690
+ G CPQGY + C D NEC+ P C C N GSY+C CP G S
Sbjct: 333 VRGEVGADCPQGY-KRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR 391
Query: 2691 SAC-----HDVNEC---SSSKNPCNYGCSNTEGGYLC-------------GCPPGYYRVG 2729
+ C + + C S ++ C + + LC CP
Sbjct: 392 TQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAF 451
Query: 2730 QGHCVSGMGFN---KGQYLSLDTEVD------EENALSPEACYECKINGYSKKDSRQKRS 2780
+ C +G G++ Q L++ E D + P+ E +D+ ++R
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2781 IHEPDPTAVEQISLES---------------VDMDSPVNMKFNLSHLGSKEHILELRP 2823
+ P + E+ +S + SP M++ L L +E+ P
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP 569
Score = 54.7 bits (130), Expect = 1e-06
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 512 PTVSSYRCECNMGYKQDANGDCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTK 570
P +C GYK+ + C D++EC C +GDC+N PGSY C C G P++
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR 391
Query: 571 QACI 574
CI
Sbjct: 392 TQCI 395
Score = 53.5 bits (127), Expect = 3e-06
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 1868 INSPGSYRCE----CAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF 1923
+ PG R E C G+K + C D NEC +P VC HG C++ GSY+C+C G
Sbjct: 327 VQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGH 385
Query: 1924 KASQDQTMCMDVDECERHPC 1943
+T C+ E+ C
Sbjct: 386 SLGPSRTQCIADKPEEKSLC 405
Score = 53.1 bits (126), Expect = 4e-06
Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 28/156 (17%)
Query: 718 PFPGAVTKSECCCANPDYGFGEP-CQPCPAKNSAEFHGLCSSG-----VGI--------- 762
P PG +TK E CC + +G+ C CP ++ G+ G VG
Sbjct: 293 PLPG-LTKQEDCCGSIGTAWGQSKCHKCP---QLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 763 -TVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCI---DIDECLVNR 818
+ +DINECA+ P +C +G C N GSYRC C G+ S CI ++ L R
Sbjct: 349 NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFR 407
Query: 819 LLCDNGLCRNTPGS----YSCTCPPGYVFRTETETC 850
L+ C++ + C C G + + C
Sbjct: 408 LVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC 443
Score = 52.0 bits (123), Expect = 9e-06
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 1953 GSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
G C G++ ++ C DI+EC+ VCR+G C N GS++C+C G+ L P
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECA--MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2013 NCI 2015
CI
Sbjct: 393 QCI 395
Score = 48.1 bits (113), Expect = 1e-04
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 175 CGQP-VCENG-CQNGGRCIGPNRCACVYGFT-GP---QC--ERDYRTGPCFTQVNNQ-MC 225
C P VC +G C N G RC C G + GP QC ++ CF V+ + C
Sbjct: 359 CAMPGVCRHGDCLNNP---GSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQC 415
Query: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
Q LT + T+ LCC ++G+AWG C+ CP
Sbjct: 416 QHPLTTRL-TRQLCCCSVGKAWGARCQRCP 444
Score = 47.4 bits (111), Expect = 2e-04
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 554 GSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGK 613
G C G++R + C DI+EC GV C++G C+N GS++C+C G L
Sbjct: 335 GEVGADCPQGYKRLNSTH-CQDINECAMPGV-CRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 614 NCV 616
C+
Sbjct: 393 QCI 395
Score = 43.1 bits (100), Expect = 0.004
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1911 LQGSYQCICHNGFKASQDQTMCMDVDECERHP-CGNGTCKNTVGSYNCLCYPGFEL 1965
++G C G+K + T C D++EC C +G C N GSY C+C PG L
Sbjct: 333 VRGEVGADCPQGYKRL-NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
Score = 40.0 bits (92), Expect = 0.034
Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 30/164 (18%)
Query: 53 GSEGGFLAPEYREEGAA---------------VASRVRR--RGQQDVLRGPNVCGSRFHS 95
G+ GG LAPE R GAA + RV G++ G + RF
Sbjct: 6 GAAGG-LAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKV 64
Query: 96 YCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISS---TCGSKSIQQCSVR 152
P + C+ CR+SC G NM S+ T + C +
Sbjct: 65 VFAP----VICKRTCLKGQCRDSCQQG----SNMTLIGENGHSTDTLTGSGFRVVVCPLP 116
Query: 153 CMNGGTCAD-DHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNR 195
CMNGG C+ + C C + G +C P G GG G +R
Sbjct: 117 CMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSR 160
Score = 37.7 bits (86), Expect = 0.17
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 19/75 (25%)
Query: 149 CSVRCMNGGTCADDHCQCQKGYIGTYCGQP---------------VCENGCQNGGRCIGP 193
C C+ G C D CQ+G T G+ VC C NGG+C
Sbjct: 71 CKRTCLKG-QCRDS---CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSR 126
Query: 194 NRCACVYGFTGPQCE 208
N+C C FTG C+
Sbjct: 127 NQCLCPPDFTGRFCQ 141
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 432 bits (1110), Expect = e-120
Identities = 310/1044 (29%), Positives = 431/1044 (41%), Gaps = 203/1044 (19%)
Query: 1014 HPVPGKFRMDACCCAVGAAWG-TECEECP--------KPGTKEYETL--CPRGAGFANRG 1062
+P+PG + + CC ++G AWG ++C +CP KPG E CP+G N
Sbjct: 292 NPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNST 351
Query: 1063 DVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRIS 1122
+DINEC A PG+C +G C N GS++C C G +L C I +
Sbjct: 352 HC-------QDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC--IADKPEE 401
Query: 1123 PDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE-----CERNPLLCRGGTCVNT 1177
LC + S E +C + C + + C+R P GT
Sbjct: 402 KSLCFRLV------SPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPT---DGTAAFK 452
Query: 1178 EGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDR 1237
E C G+ + S + E S L +G S P + T +
Sbjct: 453 E---ICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEE 509
Query: 1238 QGCTD---IDECMIMNGGCDTQCTNSEGSYECSCSEGYAL--------MPDGRSCADI-- 1284
+G T + E + T T Y S +P RS +I
Sbjct: 510 RGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP 569
Query: 1285 ------DECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 1338
DEC N +IC G+C P +Y C C G+ + + C+DVNEC+
Sbjct: 570 TQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGR 629
Query: 1339 GECENTKGSFICHCQLGYSVKKGTTG--CTDVDECEIGAHNCDMHASCLNIPGSFKCSCR 1396
G C NT GS+ CHC GY + G G C D++EC H C C+N PG +KC+C
Sbjct: 630 GICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCY 688
Query: 1397 EGWIGNGIK---CIDLDECSNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGF-TCSDVD 1451
G+ + C D+DEC + + C + +C N PGS++C AC G+ G C DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPS-SCP-DGKCENKPGSFKCIACQPGYRSQGGGACRDVN 746
Query: 1452 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPG 1511
ECAE + C G C N+PG++RC C G+ PA D RSC D+DEC ++C G C+N PG
Sbjct: 747 ECAEG-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPG 805
Query: 1512 MFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQL------- 1564
F C C GY L R +C DIDEC P C+ G C+NT G Y C CP +L
Sbjct: 806 SFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 1565 ------------NPTGV-----------------------GCVD----NRVGNCYLKFGP 1585
P G GC + + CYL F
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-- 923
Query: 1586 RGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE--TCPPVNSTEYYTLCPGGEGFRPNP 1643
D ++ C++ + V++ CCCSLG WG+ CE CP +S E+++LCP G+G+ +
Sbjct: 924 --DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDN 981
Query: 1644 ITI-----ILEDIDECQELPG-LCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECF 1697
+ DIDEC +C+ G C+NT ++C C QG+Y + C D+DEC
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECL 1041
Query: 1698 ---------------------------------------------AHPGVCGPGTCYNTL 1712
P C PG C N
Sbjct: 1042 DESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLP 1101
Query: 1713 GNYTCICPPEYMQVNGGHNCM---------DMRKSFCY--RSYNGTTCENELPFNVTKRM 1761
G+Y C C P ++ G +C R+ C+ R +G +T
Sbjct: 1102 GSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 1161
Query: 1762 CCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDI-----------HTGKAVDID 1810
CCC G+ W C PCP G + +D D D
Sbjct: 1162 CCC--RQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSD 1219
Query: 1811 ECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS--NGDNLCQRNADCI 1868
EC+ C +G C+ + G CECP GF + C DIDEC N L ++ C+
Sbjct: 1220 ECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 1274
Query: 1869 NSPGSYRCECAAGFKLS-PNGACV 1891
N+ GS+RC C AGF S P+GACV
Sbjct: 1275 NTSGSFRCVCKAGFARSRPHGACV 1298
Score = 407 bits (1046), Expect = e-113
Identities = 239/742 (32%), Positives = 342/742 (46%), Gaps = 90/742 (12%)
Query: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
+ +EC+ +C +G+C + C CN G+ + R C D++EC P G GIC+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1133 NTPGSFECECFEGYESGFMMM-KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL 1191
NT GS+ C C GY ++C+D++EC + L GG C+N G ++C+C G+ L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 1192 SPSRED-CVDINECSLSDNLCRNGKCVNMIGTYQC-SCNPGYQATPDRQGCTDIDECMIM 1249
SR C DI+EC + C +GKC N G+++C +C PGY++ C D++EC
Sbjct: 694 KASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYRSQGGG-ACRDVNECAEG 751
Query: 1250 NGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1309
+ C N GS+ C+C++GYA PDGRSC D+DECE D+CD G C+N PG ++C
Sbjct: 752 SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQCQ 810
Query: 1310 CYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVD 1369
C G+ S D C D++ECD + C+ G+C NT GS+ C C G+ + G C D+D
Sbjct: 811 CLSGYHLSRDRSHCEDIDECDFPA-ACIGGDCINTNGSYRCLCPQGHRLVGGRK-CQDID 868
Query: 1370 ECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLD------EC--------- 1412
EC C H +C N+ GS+ C C EG+ + C +++ EC
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 1413 ------SNGTHQ---CSINA----QC------VNTPGSYRCACSEG--FTGDGFTCS--- 1448
+N T Q CS+ A C V + + C +G +T D +
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 988
Query: 1449 ----DVDECAE-NINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVF 1503
D+DEC +C+ G+C+N Y C C+ GF + C D+DEC ++ C
Sbjct: 989 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN 1048
Query: 1504 GTCNNLPGMFHCICDDGYELDRTGGNC-----TDIDECADPINCVNGLCVNTPGRYECNC 1558
G C N G + C C E C D+DEC DP C G CVN PG Y C C
Sbjct: 1049 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 1108
Query: 1559 PPDFQLNPTGVGC---------VDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS 1609
P + P+G C R C+ RG+ + G ++ CCC
Sbjct: 1109 RPPWVPGPSGRDCQLPESPAERAPERRDVCW---SQRGEDGMCAGPLAGPALTFDDCCCR 1165
Query: 1610 LGKAWGNPCETCPP-----------VNSTEYYTLCPGGEGFRPNPITIILEDIDECQELP 1658
G+ WG C CPP S ++ P G P ED DEC+
Sbjct: 1166 QGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR--- 1222
Query: 1659 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC--FAHPG-VCGPGTCYNTLGNY 1715
C G C+ G CECP G+ L C DIDEC G +C C NT G++
Sbjct: 1223 --CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSF 1280
Query: 1716 TCICPPEYMQVNGGHNCMDMRK 1737
C+C + + C+ R+
Sbjct: 1281 RCVCKAGFARSRPHGACVPQRR 1302
Score = 344 bits (883), Expect = 6e-94
Identities = 236/768 (30%), Positives = 329/768 (42%), Gaps = 134/768 (17%)
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCT 2073
+T+EC C G C + C C PGY ++ C+D+NEC+ +P G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 2074 NTPGGFQCLCPPGFVL--SDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
NT G + C C G+ L GR C D + C+ P C
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNE-----------CAKPHLCGDGGF---CINF 679
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
PG ++ C G+ S ED++EC + P C +G+C N
Sbjct: 680 PGH----------------YKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKP 722
Query: 2192 GSFRC-ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPM-M 2249
GSF+C C GY G C D +EC+ G+PC G C N+ GSF C C +G+ P P
Sbjct: 723 GSFKCIACQPGYRSQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR 781
Query: 2250 NCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRG 2309
+C D++EC + C NT GS++C C GY L D+ C+D+DEC G
Sbjct: 782 SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD---FPAACIG 838
Query: 2310 MMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRCECNEG 2368
C N G++ C+CP G R G C D +EC P +C +G C N+ GSY C C+EG
Sbjct: 839 GDCINTNGSYRCLCPQGH-RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 2369 FQSSSSGTECLDNRQGL----CFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCEL 2424
F + C + Q C+ T+ + + N VT+ ECCC G GWG CE+
Sbjct: 898 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN-VTQQECCCSLGAGWGDHCEI 956
Query: 2425 --CPLPGTAQYKKICPHGPGYTTDG----------RDIDECKVMPN-LCTNGQCINTMGS 2471
CP+ +A++ +CP G GYT D RDIDEC + + +C G+C+NT
Sbjct: 957 YPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPG 1016
Query: 2472 FRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTC- 2530
+ C+CK G+ D + C+D+DEC N +C+NT G Y+C+C + C
Sbjct: 1017 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCL 1076
Query: 2531 ----KDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF-------------TQHHTACIDNN 2573
D+DECQ CVN G + C+C P + + A +
Sbjct: 1077 SPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRD 1136
Query: 2574 ECGSQPSLCGAKGICQNTPGSFS-----CECQRGFSLDA---------TGLNC------- 2612
C SQ G G+C + C C++G A G +C
Sbjct: 1137 VCWSQR---GEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSES 1193
Query: 2613 ----------------------EDVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQW 2649
ED DEC RC G C GG C CP G+
Sbjct: 1194 NSFWDTSPLLLGKPPRDEDSSEEDSDEC----RCVSGRCVPRPGGAVCECPGGFQLDASR 1249
Query: 2650 NQCVDENECSNPN----ACGSASCYNTLGSYKCACPSGFSFDQFSSAC 2693
+CVD +EC N C S C NT GS++C C +GF+ + AC
Sbjct: 1250 ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 341 bits (874), Expect = 7e-93
Identities = 210/602 (34%), Positives = 284/602 (47%), Gaps = 76/602 (12%)
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRC-ECNMGYKQDANGDCIDVDECTS-NPCTNGDCV 550
+ ID C+ ++ C +G+C S++C C GY+ G C DV+EC +PC+ G C
Sbjct: 702 EDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCE 760
Query: 551 NTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTT 610
N PGS+ C C G+ P ++C+D+DEC + G +C NG C NT GSFQC C +G+ L+
Sbjct: 761 NLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSR 819
Query: 611 DGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC-QTPGICM 669
D +C D DEC C+ G CIN +GS++C+C G L GR C D+DEC Q P +C+
Sbjct: 820 DRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPSLCL 878
Query: 670 -NGHCINSEGSFRCDCPPGLAVGMDGRVCVDT---HMRSTCYGGIKKGV-CVRPFPGAVT 724
+G C N +GS+ C C G D C + H + CY V C VT
Sbjct: 879 PHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT 938
Query: 725 KSECCCANPDYGFGEPCQ--PCPAKNSAEFHGLCSSGVGITVDG----------RDINEC 772
+ ECCC+ G+G+ C+ PCP +SAEFH LC G G T D RDI+EC
Sbjct: 939 QQECCCSL-GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDEC 997
Query: 773 AL-DPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPG 831
L +IC G C N + Y C C G+ D + C+D+DECL + C NG+C NT G
Sbjct: 998 MLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECL-DESNCRNGVCENTRG 1056
Query: 832 SYSCTCPPGYVFRTETETC-----EDINECESNP-CVNGACRNNLGSFNCECSPGSKLSS 885
Y C C P + C D++EC+ C G C N GS+ CEC P
Sbjct: 1057 GYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGP 1116
Query: 886 TGLIC---------IDSLKGTCWLNI-QDSRCEVNINGATLK-SECCATLGAAWGSPCER 934
+G C + CW +D C + G L +CC G WG+ C
Sbjct: 1117 SGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRP 1176
Query: 935 CELDTA---CPRGLA-----------------RIKGVTCEDVNECEVFPGVCPNGRCVNS 974
C A CP + R + + ED +EC C +GRCV
Sbjct: 1177 CPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPR 1231
Query: 975 KGSFHCECPEGLTLDGTGRVCLDI----RMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
G CECP G LD + C+DI + Q L + C++ G FR C C G
Sbjct: 1232 PGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVN-TSGSFR---CVCKAG 1287
Query: 1031 AA 1032
A
Sbjct: 1288 FA 1289
Score = 340 bits (872), Expect = 1e-92
Identities = 225/721 (31%), Positives = 309/721 (42%), Gaps = 129/721 (17%)
Query: 1782 PGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSY 1841
PG D+ C PG+ VD++EC+ P G+C+N GS+ C C G+
Sbjct: 592 PGPPDYSCHCN--PGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRL 649
Query: 1842 NDLL--LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG--ACVDRNECL 1897
+ C D++EC+ +LC CIN PG Y+C C G++L + C D +EC
Sbjct: 650 HVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECR 708
Query: 1898 EIPNVCSHGLCVDLQGSYQCI-CHNGFKASQDQTMCMDVDEC-ERHPCGNGTCKNTVGSY 1955
+ P+ C G C + GS++CI C G++ SQ C DV+EC E PC G C+N GS+
Sbjct: 709 D-PSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSF 766
Query: 1956 NCLCYPGFE-LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 2014
C C G+ CLD+DEC + G VC NG C N GSF+C C GY L+ D +C
Sbjct: 767 RCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC 824
Query: 2015 IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE-VKSENCIDINECDEDPNICL-FGSC 2072
D +EC P +C G C N GS+RC+CP G+ V C DI+EC +DP++CL G+C
Sbjct: 825 EDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGAC 883
Query: 2073 TNTPGGFQCLCPPGFVLSDNGRRCFDTRQSF----CFTNFENGK-CSVPKAFNTTKAKCC 2127
N G + C+C GF + + C + Q C+ NF++ C A N T+ +CC
Sbjct: 884 KNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECC 943
Query: 2128 CSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGTVPSLH------DTREDVNEC-LES 2178
CS G GWGD CE+ CP F LCP G G + D++EC L
Sbjct: 944 CSL--GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFG 1001
Query: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT----------- 2227
IC G+C+NT + C C G+ D + CVD DEC + C NG
Sbjct: 1002 SEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCA 1061
Query: 2228 -----------------------------------CTNVIGSFECNCNEGFEPGPM-MNC 2251
C N+ GS+ C C + PGP +C
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1121
Query: 2252 EDINECAQNPLLCAFRCMNTFGSYE-CTCPI-GYALREDQKMCK---------------- 2293
+ A+ C + G C P+ G AL D C+
Sbjct: 1122 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRG 1181
Query: 2294 ----------------------------DLDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
D D E +C C G +C CP
Sbjct: 1182 AGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPG 1241
Query: 2326 GMARRPDGEGCVDENECRT---KPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
G CVD +ECR + +C++ RCVN GS+RC C GF S C+ R
Sbjct: 1242 GFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1301
Query: 2383 Q 2383
+
Sbjct: 1302 R 1302
Score = 337 bits (863), Expect = 1e-91
Identities = 237/763 (31%), Positives = 327/763 (42%), Gaps = 155/763 (20%)
Query: 1800 DIHTGKAVDIDECKEIPGICAN-------------------------------------- 1821
+I + + DEC+ IC +
Sbjct: 566 EIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPC 625
Query: 1822 ----GVCINQIGSFRCECPTGFSYNDLL--LVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
G+C+N GS+ C C G+ + C D++EC+ +LC CIN PG Y+
Sbjct: 626 GPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYK 684
Query: 1876 CECAAGFKL--SPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI-CHNGFKASQDQTMC 1932
C C G++L S C D +EC + P+ C G C + GS++CI C G++ SQ C
Sbjct: 685 CNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYR-SQGGGAC 742
Query: 1933 MDVDEC-ERHPCGNGTCKNTVGSYNCLCYPGF-ELTHNNDCLDIDECSSFFGQVCRNGRC 1990
DV+EC E PC G C+N GS+ C C G+ CLD+DEC + G VC NG C
Sbjct: 743 RDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGIC 800
Query: 1991 FNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE-V 2049
N GSF+C C GY L+ D +C D +EC P +C G C N GS+RC+CP G+ V
Sbjct: 801 SNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGHRLV 859
Query: 2050 KSENCIDINECDEDPNICL-FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSF----C 2104
C DI+EC +DP++CL G+C N G + C+C GF + + C + Q C
Sbjct: 860 GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Query: 2105 FTNFENGK-CSVPKAFNTTKAKCCCSKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGT 2161
+ NF++ C A N T+ +CCCS G GWGD CE+ CP F LCP G G
Sbjct: 920 YLNFDDTVFCDSVLATNVTQQECCCSL--GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGY 977
Query: 2162 VPSLH------DTREDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
+ D++EC L IC G+C+NT + C C G+ D + CVD
Sbjct: 978 TQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDV 1037
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEPGP-MMNC-----EDINECAQNPLLC-AFR 2267
DEC + C NG C N G + C C E P C D++EC Q+P C R
Sbjct: 1038 DECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGR 1096
Query: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHD----CESR----GMMCKNLIGTF 2319
C+N GSY C C + + C+ + AE + C S+ GM L G
Sbjct: 1097 CVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPA 1156
Query: 2320 MCI-----------------CPP-------------------------GMARRPDGEGCV 2337
+ CPP G R +
Sbjct: 1157 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEE 1216
Query: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQM 2397
D +ECR C +GRCV G CEC GFQ +S C+D + C+
Sbjct: 1217 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDE-----------CR- 1259
Query: 2398 ASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHG 2440
+ R L+ KSE C + + C+ A + + PHG
Sbjct: 1260 ELNQRGLLCKSERCVNTSGSFRCVCK-------AGFARSRPHG 1295
Score = 324 bits (831), Expect = 7e-88
Identities = 231/748 (30%), Positives = 313/748 (41%), Gaps = 132/748 (17%)
Query: 496 DICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSNPCT--NGDCVNT 552
D C+ + N+C +G C+P Y C CN GY+ C+DV+EC + PC G C+NT
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT 635
Query: 553 PGSYYCKCHAGFQRTPTK--QACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTT 610
GSY C C+ G++ ++C+D++EC + + G C+N G ++C C G+ L
Sbjct: 636 GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKA 695
Query: 611 DGKN-CVDHDECTTTNMCLNGMCINEDGSFKCI-CKPGFVLAPNGRYCTDVDECQTPGIC 668
C D DEC + C +G C N+ GSFKCI C+PG+ + G C DV+EC C
Sbjct: 696 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY-RSQGGGACRDVNECAEGSPC 754
Query: 669 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGG--IKKGVCVRPFPGAVTKS 726
G C N GSFRC C G A DGR C+D C G G+C PG+
Sbjct: 755 SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV---DECEAGDVCDNGICSNT-PGSF--- 807
Query: 727 ECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG------------------RD 768
+C C + Y C + +F C G I +G +D
Sbjct: 808 QCQCLS-GYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQD 866
Query: 769 INECALDPDICA-NGICENLRGSYRCNCNSGYEPDASGRNCIDID------ECLVN---R 818
I+EC+ DP +C +G C+NL+GSY C C+ G+ P C +++ EC +N
Sbjct: 867 IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT 926
Query: 819 LLCDNGLCRNTPGSYSCT--------------------------CPPGYVFRTETETCE- 851
+ CD+ L N C CP G + +
Sbjct: 927 VFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY 986
Query: 852 ------DINECE---SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI 902
DI+EC S C G C N + C C G L C+D C +
Sbjct: 987 GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDV--DEC---L 1041
Query: 903 QDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVF 962
+S C + T CA A SP +R L P + DV+EC+
Sbjct: 1042 DESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLS---PEEM---------DVDECQD- 1088
Query: 963 PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC---------LDIRMEQCYLKWDEDE-C 1012
P C GRCVN GS+ CEC +GR C R + C+ + ED C
Sbjct: 1089 PAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMC 1148
Query: 1013 IHPVPGK-FRMDACCCAVGAAWGTECEECPKPGTKEYETLCP----RGAGFANRGDVLTG 1067
P+ G D CCC G WG +C CP G + CP F + +L G
Sbjct: 1149 AGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLLLG 1205
Query: 1068 RP------FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRI 1121
+P +D +EC+ C G+C G C C GF LD C DIDECR
Sbjct: 1206 KPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRE 1260
Query: 1122 SPD---LCGSGICVNTPGSFECECFEGY 1146
LC S CVNT GSF C C G+
Sbjct: 1261 LNQRGLLCKSERCVNTSGSFRCVCKAGF 1288
Score = 307 bits (787), Expect = 9e-83
Identities = 248/815 (30%), Positives = 341/815 (41%), Gaps = 173/815 (21%)
Query: 1930 TMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCR 1986
T + DEC ++ CG+G C Y+C C PG+ + C+D++EC + + C
Sbjct: 570 TQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA---EPCG 626
Query: 1987 NGR--CFNEIGSFKCLCNEGYELT--PDGKNCIDTNECVALPGSCSPGT-CQNLEGSFRC 2041
GR C N GS+ C CN GY L G++C+D NEC A P C G C N G ++C
Sbjct: 627 PGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKC 685
Query: 2042 ICPPGYEVKSEN---CIDINECDEDPNICLFGSCTNTPGGFQCL-CPPGFVLSDNGRRCF 2097
C PGY +K+ C DI+EC DP+ C G C N PG F+C+ C PG+ S G C
Sbjct: 686 NCYPGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGY-RSQGGGACR 743
Query: 2098 DTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPY 2157
D + E CS GW CE P +F+ C
Sbjct: 744 DVNECA-----EGSPCS-------------------PGW---CENLPG----SFRCTCAQ 772
Query: 2158 GHGTVPSLHDTRE--DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTD 2215
G+ P D R DV+EC E+ +C NG C NT GSF+C+C GY+L C D D
Sbjct: 773 GYAPAP---DGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDID 828
Query: 2216 ECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCA--FRCMNTFG 2273
EC C G C N GS+ C C +G C+DI+EC+Q+P LC C N G
Sbjct: 829 ECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQG 888
Query: 2274 SYECTCPIGYALREDQKMCKDLD------ECAEGLHDCESRGMMCKNLIGTFM----CIC 2323
SY C C G+ +DQ C++++ EC D + C +++ T + C C
Sbjct: 889 SYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT----VFCDSVLATNVTQQECCC 944
Query: 2324 PPGM--------------------ARRPDGEGCVDEN--------------ECRT-KPGI 2348
G + PDG+G +N EC I
Sbjct: 945 SLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI 1004
Query: 2349 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKS 2408
C+ G+CVN Y C C +GF + EC+D + C S+ RN V
Sbjct: 1005 CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDE-----------CLDESNCRNGV--- 1050
Query: 2409 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINT 2468
C+ RG G++C P + ++ C + + D+DEC+ P C G+C+N
Sbjct: 1051 ---CENTRG-GYRCACTPPAEYSPAQRQC-----LSPEEMDVDECQ-DPAACRPGRCVNL 1100
Query: 2469 MGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
GS+RC C+ + SG C + +SP + E C RG EDG
Sbjct: 1101 PGSYRCECRPPWVPGPSGRDC----QLPESPAE-----RAPERRDVCWSQRG----EDGM 1147
Query: 2529 TCKDLDECQTKQHNCQFLCVNTLG-GFTCK-CPPGFTQHH---TACIDNNECGSQPSLCG 2583
L +C C G G C+ CPP H + N+ + P L G
Sbjct: 1148 CAGPLAGPALTFDDC--CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLG 1205
Query: 2584 ------------------AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHR- 2623
G C PG CEC GF LDA+ C D+DEC + N R
Sbjct: 1206 KPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRG 1265
Query: 2624 --CQ-HGCQNILGGYRCGCPQGYIQHYQWNQCVDE 2655
C+ C N G +RC C G+ + CV +
Sbjct: 1266 LLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1300
Score = 296 bits (757), Expect = 3e-79
Identities = 228/764 (29%), Positives = 319/764 (41%), Gaps = 155/764 (20%)
Query: 943 RGLARIKGVTCEDVNECEVFPGVCPNGRCV------------------------------ 972
R I + +EC + +C +G CV
Sbjct: 562 RSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE 621
Query: 973 ------------NSKGSFHCECPEG--LTLDGTGRVCLDI-RMEQCYLKWDEDECIHPVP 1017
N+ GS++C C G L + GR C+D+ + +L D CI+ P
Sbjct: 622 AEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCIN-FP 680
Query: 1018 GKFRMDACCCAVG----AAWGTECE---ECPKPGTKEYETLCPRGAGFANRGD--VLTGR 1068
G ++ C C G A+ CE EC P + CP G G + +
Sbjct: 681 GHYK---CNCYPGYRLKASRPPVCEDIDECRDPSS------CPDGKCENKPGSFKCIACQ 731
Query: 1069 PFY--------KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR 1120
P Y +D+NEC A C+ G C N GSF+C C G+A + R+C D+DEC
Sbjct: 732 PGYRSQGGGACRDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECE 790
Query: 1121 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGS 1180
+ D+C +GIC NTPGSF+C+C GY +C DIDEC+ P C GG C+NT GS
Sbjct: 791 -AGDVCDNGICSNTPGSFQCQCLSGYHLS-RDRSHCEDIDECD-FPAACIGGDCINTNGS 847
Query: 1181 FQCDCPLGHELSPSREDCVDINECSLSDNLC-RNGKCVNMIGTYQCSCNPGYQATPDRQG 1239
++C CP GH L R+ C DI+ECS +LC +G C N+ G+Y C C+ G+ T D+ G
Sbjct: 848 YRCLCPQGHRLVGGRK-CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHG 906
Query: 1240 CTDID------ECMIMNGG---CDTQCTNSEGSYECSCSEG------------------- 1271
C +++ EC + CD+ + EC CS G
Sbjct: 907 CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE 966
Query: 1272 -YALMPDGRSCA--------------DIDECE-NNPDICDGGQCTNIPGEYRCLCYDGFM 1315
++L PDG+ DIDEC +IC G+C N Y C C GF
Sbjct: 967 FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFY 1026
Query: 1316 ASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC-----TDVDE 1370
++ C+DV+EC L+ + C G CENT+G + C C C DVDE
Sbjct: 1027 YDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDE 1085
Query: 1371 CEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKC-----------IDLDECSNGTH 1417
C+ A C+N+PGS++C CR W+ +G C D C +
Sbjct: 1086 CQDPA--ACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG 1143
Query: 1418 QCSINAQCVNTPGSY--RCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCE 1475
+ + A + P C C +G G G C + C Q +
Sbjct: 1144 EDGMCAGPLAGPALTFDDCCCRQG-RGWGAQCRPCPPRGAGSH-CPTSQSESNSFWDTSP 1201
Query: 1476 CEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDE 1535
+G P + S +D DEC CV G C PG C C G++LD + C DIDE
Sbjct: 1202 LLLGKPPRDEDSSEEDSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDE 1257
Query: 1536 CAD----PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
C + + C + CVNT G + C C F + CV R
Sbjct: 1258 CRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1301
Score = 283 bits (725), Expect = 1e-75
Identities = 229/801 (28%), Positives = 320/801 (39%), Gaps = 185/801 (23%)
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP--GT 1707
+ DEC+ +C G C+ + C C GY R C D++EC A P CGP G
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGPGRGI 631
Query: 1708 CYNTLGNYTCICPPEY-MQVN-GGHNCMDMRKSFCYRSY---NGTTCENELPFNVTKRMC 1762
C NT G+Y C C Y + V GG +C+D+ + C + + +G C N P + K C
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNE--CAKPHLCGDGGFCIN-FPGHY-KCNC 687
Query: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANG 1822
Y + + CE DIDEC++ P C +G
Sbjct: 688 YPGYRLKASRPPVCE------------------------------DIDECRD-PSSCPDG 716
Query: 1823 VCINQIGSFRC-ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAG 1881
C N+ GSF+C C G+ + C D++EC+ G C N PGS+RC CA G
Sbjct: 717 KCENKPGSFKCIACQPGYR-SQGGGACRDVNECAEGSPCSP--GWCENLPGSFRCTCAQG 773
Query: 1882 FKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE- 1939
+ +P+G +C+D +EC E +VC +G+C + GS+QC C +G+ S+D++ C D+DEC+
Sbjct: 774 YAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF 832
Query: 1940 RHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKC 1999
C G C NT GSY CLC G L C DIDECS +G C N GS+ C
Sbjct: 833 PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVC 892
Query: 2000 LCNEGYELTPDGKNC-----------------------------IDTNECVALPGSCSPG 2030
+C+EG+ T D C + EC G+
Sbjct: 893 VCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGD 952
Query: 2031 TCQ------NLEGSFRCICPPGYEVKSENCI---------DINECD-EDPNICLFGSCTN 2074
C+ F +CP G +N I DI+EC IC G C N
Sbjct: 953 HCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVN 1012
Query: 2075 TPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGE 2134
T G++C C GF N C D + +N NG C NT C P E
Sbjct: 1013 TQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE-----NTRGGYRCACTPPAE 1067
Query: 2135 GWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSF 2194
Y L DV+EC + P C G+C+N GS+
Sbjct: 1068 ----------------------YSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSY 1104
Query: 2195 RCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGS---------------FECNC 2239
RCEC + +G C + + P C + G +C C
Sbjct: 1105 RCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCC 1164
Query: 2240 NEG-----------------------------FEPGPMM-----NCEDINECAQNPLLC- 2264
+G ++ P++ ED +E + C
Sbjct: 1165 RQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV 1224
Query: 2265 AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCK-----NLIGTF 2319
+ RC+ G C CP G+ L + C D+DEC E RG++CK N G+F
Sbjct: 1225 SGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRE----LNQRGLLCKSERCVNTSGSF 1280
Query: 2320 MCICPPGMAR-RPDGEGCVDE 2339
C+C G AR RP G CV +
Sbjct: 1281 RCVCKAGFARSRPHG-ACVPQ 1300
Score = 244 bits (623), Expect = 9e-64
Identities = 191/582 (32%), Positives = 247/582 (42%), Gaps = 116/582 (19%)
Query: 2213 DTDECSIG-NPCGNGTCTNVIGSFECNCNEGFEPGPMMN-CEDINECAQNPLLCAFR--- 2267
+TDEC + N CG+G C + C+CN G+ P C D+NEC P C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGPGRGI 631
Query: 2268 CMNTFGSYECTCPIGYALREDQ--KMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
CMNT GSY C C GY L + C DL+ECA+ H C G C N G + C C P
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGF-CINFPGHYKCNCYP 689
Query: 2326 GM---ARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRC-ECNEGFQSSSSGTECLDN 2381
G A RP C D +ECR P C +G+C N GS++C C G++S G C D
Sbjct: 690 GYRLKASRPPV--CEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDV 745
Query: 2382 RQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGR---GWGHQCELCPLPGTAQYKKICP 2438
+ C +G GW CE LPG+ ++ C
Sbjct: 746 NE---------------------------CAEGSPCSPGW---CE--NLPGS--FRCTCA 771
Query: 2439 HGPGYTTDGR---DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
G DGR D+DEC+ ++C NG C NT GSF+C C GY + C D+DEC
Sbjct: 772 QGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC 830
Query: 2496 SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGG 2553
C NT GSY+C CP+G+ L G+ C+D+DEC C C N G
Sbjct: 831 DFPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPSLCLPHGACKNLQGS 889
Query: 2554 FTCKCPPGFT--------------QHHTACIDNNE----CGS-------QPSLCGAKGI- 2587
+ C C GFT H C N + C S Q C + G
Sbjct: 890 YVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAG 949
Query: 2588 ----CQNTP------GSFSCECQ--RGFSLDATGLNC-----EDVDECD--GNHRCQHG- 2627
C+ P F C +G++ D +N D+DEC G+ C+ G
Sbjct: 950 WGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGK 1009
Query: 2628 CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD 2687
C N GY C C QG+ +CVD +EC + + C + C NT G Y+CAC +
Sbjct: 1010 CVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYS 1069
Query: 2688 QFSSAC-----HDVNECSSSKNPCNYG-CSNTEGGYLCGCPP 2723
C DV+EC C G C N G Y C C P
Sbjct: 1070 PAQRQCLSPEEMDVDECQDPA-ACRPGRCVNLPGSYRCECRP 1110
Score = 242 bits (617), Expect = 4e-63
Identities = 176/566 (31%), Positives = 226/566 (39%), Gaps = 103/566 (18%)
Query: 2253 DINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM 2311
+ +EC N +C C+ Y C C GY + C D++EC C +
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA--EPCGPGRGI 631
Query: 2312 CKNLIGTFMCICPPGMARR--PDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRCECNEG 2368
C N G++ C C G G CVD NEC KP +C + G C+N G Y+C C G
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 2369 FQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLP 2428
++ +S +C+ R+ C DG +CE P
Sbjct: 691 YRLKASRPP----------------VCEDIDECRD----PSSCPDG------KCENKP-- 722
Query: 2429 GTAQYKKICPHGPGYTTDG----RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDI 2484
+K I PGY + G RD++EC + C+ G C N GSFRC C GY
Sbjct: 723 --GSFKCIACQ-PGYRSQGGGACRDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAP 778
Query: 2485 SGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ 2544
G SC+D+DEC N IC NT GS+QC C GY L D C+D+DEC
Sbjct: 779 DGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG 838
Query: 2545 FLCVNTLGGFTCKCPPGFTQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGF 2603
C+NT G + C CP G C D +EC PSLC G C+N GS+ C C GF
Sbjct: 839 GDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGF 898
Query: 2604 SLDATGLNCEDVDECDGNHRC-------------------QHGCQNILGG--------YR 2636
+ CE+V++ C Q C LG Y
Sbjct: 899 TPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYP 958
Query: 2637 CG----------CP--QGYIQ-----HYQWNQCVDENECS--NPNACGSASCYNTLGSYK 2677
C CP +GY Q +Y D +EC C C NT Y+
Sbjct: 959 CPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYE 1018
Query: 2678 CACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGC-PPGYYRVGQGHCVSG 2736
C C GF +D C DV+EC N N C NT GGY C C PP Y Q C+S
Sbjct: 1019 CYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLS- 1077
Query: 2737 MGFNKGQYLSLDTEVDEENALSPEAC 2762
E+D + P AC
Sbjct: 1078 -----------PEEMDVDECQDPAAC 1092
Score = 239 bits (609), Expect = 4e-62
Identities = 203/746 (27%), Positives = 286/746 (38%), Gaps = 170/746 (22%)
Query: 768 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 827
+ +EC L+ +IC +G C Y C+CN GY R C+D++EC G+C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 828 NTPGSYSCTCPPGYVFRTET--ETCEDINEC-ESNPCVNGA-CRNNLGSFNCECSPGSKL 883
NT GSY+C C GY +C D+NEC + + C +G C N G + C C PG +L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 884 -SSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSEC-----------CATLG-AAWGS 930
+S +C D + + D +CE N G+ C C + A GS
Sbjct: 694 KASRPPVCEDIDECRDPSSCPDGKCE-NKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 752
Query: 931 PC--------------------------------ERCELDTACPRGLAR----------I 948
PC + CE C G+ +
Sbjct: 753 PCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCL 812
Query: 949 KGV-------TCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
G CED++EC+ FP C G C+N+ GS+ C CP+G L G GR C DI +
Sbjct: 813 SGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDI--D 868
Query: 1002 QCYLKWDEDECI-----HPVPGKFRMDACCCAVGAAWGTE---CEECPKPGTK------- 1046
+C D C+ + G + C C G + CEE +P K
Sbjct: 869 EC--SQDPSLCLPHGACKNLQGSY---VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF 923
Query: 1047 ---------------EYETLCPRGAGFANRGDVLT------------------------- 1066
+ E C GAG+ + ++
Sbjct: 924 DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNI 983
Query: 1067 ---GRPFYKDINECKAFPG-MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRIS 1122
G P ++DI+EC F +C GKC NT ++C C GF D C D+DEC +
Sbjct: 984 VNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LD 1042
Query: 1123 PDLCGSGICVNTPGSFECECFEGYESGFMMMKNC-----MDIDECERNPLLCRGGTCVNT 1177
C +G+C NT G + C C E + C MD+DEC+ +P CR G CVN
Sbjct: 1043 ESNCRNGVCENTRGGYRCACTPPAEYS-PAQRQCLSPEEMDVDECQ-DPAACRPGRCVNL 1100
Query: 1178 EGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDR 1237
GS++C+C PS DC + E R C + G G A P
Sbjct: 1101 PGSYRCECRPPWVPGPSGRDC-QLPESPAERAPERRDVCWSQRG------EDGMCAGPLA 1153
Query: 1238 QGCTDIDECMIMNG-------------GCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1284
D+C G G + C S+ L+ G+ D
Sbjct: 1154 GPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLL--GKPPRDE 1211
Query: 1285 DECENNPDICD--GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNEC-DLNSN--ICMFG 1339
D E + D C G+C PG C C GF C+D++EC +LN +C
Sbjct: 1212 DSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1271
Query: 1340 ECENTKGSFICHCQLGYSVKKGTTGC 1365
C NT GSF C C+ G++ + C
Sbjct: 1272 RCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 236 bits (602), Expect = 2e-61
Identities = 174/591 (29%), Positives = 245/591 (41%), Gaps = 57/591 (9%)
Query: 2179 PGICSNGQCINTDGSF--RCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFE 2236
PG+ C + G+ + +C L YTGV+ V G
Sbjct: 295 PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP----------------VRGEVG 338
Query: 2237 CNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC-KDL 2295
+C +G++ +C+DINECA + C+N GSY C CP G++L + C D
Sbjct: 339 ADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 2296 DECAEGLHDCESRGMMCKNLIGTFM----CICPPGMARRPDGEGCVDENECRTKPGICEN 2351
E S C++ + T + C C G A + C + K IC
Sbjct: 399 PEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE-ICPA 457
Query: 2352 GRCVNIIGSYRCECNEGFQSSSS--GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSE 2409
G+ +I+ S++ +G S + Q L + + R + T S
Sbjct: 458 GKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSP 517
Query: 2410 CCCDGGRGWGHQC----------ELCPLPGTAQYKKICPHGPGYT-------TDGRDIDE 2452
+ H EL P + P P T + DE
Sbjct: 518 VSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDE 577
Query: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP-KPCNYICKNTEG 2511
C++ N+C +G+C+ + C C GY + C+D++EC P P IC NT G
Sbjct: 578 CRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG 637
Query: 2512 SYQCSCPRGYVLQ--EDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPGF---TQ 2564
SY C C RGY L G++C DL+EC K H C C+N G + C C PG+
Sbjct: 638 SYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPGYRLKAS 696
Query: 2565 HHTACIDNNECGSQPSLCGAKGICQNTPGSFSC-ECQRGFSLDATGLNCEDVDECDGNHR 2623
C D +EC PS C G C+N PGSF C CQ G+ G C DV+EC
Sbjct: 697 RPPVCEDIDEC-RDPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEGSP 753
Query: 2624 CQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPS 2682
C G C+N+ G +RC C QGY C+D +EC + C + C NT GS++C C S
Sbjct: 754 CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLS 813
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHC 2733
G+ + S C D++EC C NT G Y C CP G+ VG C
Sbjct: 814 GYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKC 864
Score = 222 bits (565), Expect = 5e-57
Identities = 215/783 (27%), Positives = 296/783 (37%), Gaps = 138/783 (17%)
Query: 181 ENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQ-VNNQMCQGQLTGIVCTKTLC 239
+N C +G GP +C C YR+ P V+ C+ + G + +C
Sbjct: 582 QNICGHGECVPGPPDYSC-------HCNPGYRSHPQHRYCVDVNECEAEPCGP--GRGIC 632
Query: 240 CATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTG--ACQDVDECQAIPGIC-QGGNCINTV 296
T G H C RG+ ++ G +C D++EC A P +C GG CIN
Sbjct: 633 MNTGGSYNCH-----------CNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFP 680
Query: 297 GSFECRCPAGHK-QSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV-CPRGYVTSTD 354
G ++C C G++ ++ CEDIDEC P C G+C N GS+ C+ C GY S
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGY-RSQG 738
Query: 355 GSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYR 414
G C D S G C + LPG +C C G + +C E
Sbjct: 739 GGACRDVNECAEGSPCSPGWC-ENLPG---SFRCTCAQG--YAPAPDGRSCLDVDECEAG 792
Query: 415 RLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGA 474
+C +G+ PGS + +G+ S + + P G G+
Sbjct: 793 DVCDNGI-CSNTPGSFQCQCL----SGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGS 847
Query: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCL-NGRCIPTVSSYRCECNMGYK--QDANG 531
QG + G Q ID C +LCL +G C SY C C+ G+ QD +G
Sbjct: 848 YRCLCPQGHRLVGGRKC-QDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHG 906
Query: 532 ------------------DCIDVDECTSNPCTNGDC------------------VNTPGS 555
D + D + T +C V +
Sbjct: 907 CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE 966
Query: 556 YYCKCHAGFQRTPTKQ-------ACIDIDECIQNGV-LCKNGRCVNTDGSFQCICNAGFE 607
++ C G T A DIDEC+ G +CK G+CVNT ++C C GF
Sbjct: 967 FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFY 1026
Query: 608 LTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT-----DVDEC 662
+ CVD DEC + C NG+C N G ++C C P +P R C DVDEC
Sbjct: 1027 YDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC 1086
Query: 663 QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV--------DTHMRSTCYGGI-KKG 713
Q P C G C+N GS+RC+C P G GR C R C+ + G
Sbjct: 1087 QDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDG 1146
Query: 714 VCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECA 773
+C P G + CC G+G C+PCP + + C + + D +
Sbjct: 1147 MCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLL 1203
Query: 774 LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSY 833
L G P + D DEC C +G C PG
Sbjct: 1204 L-----------------------GKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGA 1235
Query: 834 SCTCPPGYVFRTETETCEDINEC-ESNP----CVNGACRNNLGSFNCECSPGSKLSSTGL 888
C CP G+ C DI+EC E N C + C N GSF C C G S
Sbjct: 1236 VCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHG 1295
Query: 889 ICI 891
C+
Sbjct: 1296 ACV 1298
Score = 207 bits (528), Expect = 9e-53
Identities = 221/875 (25%), Positives = 318/875 (36%), Gaps = 199/875 (22%)
Query: 26 TAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLR- 84
T +P P RP PP + + P+ +AV + + D R
Sbjct: 532 TTTPARPYPELISRPSPPTMR-----------WFLPDLPPSRSAVEIAPTQVTETDECRL 580
Query: 85 GPNVCGSR--------FHSYCCPGWKTLPGGNQCI-VPICR-NSCGDG--FCSRPN---M 129
N+CG + +C PG+++ P C+ V C CG G C
Sbjct: 581 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 130 CTCSSG-QISSTCGSKS---IQQCSVR--CMNGGTCADD----HCQCQKGYIGTYCGQPV 179
C C+ G ++ G +S + +C+ C +GG C + C C GY PV
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 180 CENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLC 239
CE+ + C P+ C +CE + C QG G C
Sbjct: 701 CEDIDE----CRDPSSCP------DGKCENKPGSFKCIACQPGYRSQG---GGACRDVNE 747
Query: 240 CATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGS 298
CA CE P + C +G+ P +C DVDEC+A +C G C NT GS
Sbjct: 748 CAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNGICSNTPGS 806
Query: 299 FECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY--------- 349
F+C+C +G+ S CEDIDEC P C G+C NT GSY C+CP+G+
Sbjct: 807 FQCQCLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 350 ---VTSTDGSRCI---------DQRTGMCFSGLVNGR----------------------- 374
S D S C+ +C G +
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDD 925
Query: 375 ---CAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAG 431
C L +T+ +CCC G WG CPV S E+ LC D
Sbjct: 926 TVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPD------------ 973
Query: 432 SRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTIL 491
G G+ N YG IP
Sbjct: 974 -------GKGYTQDNNIVNYG--------IPA---------------------------- 990
Query: 492 NQTIDICK-HHANLCLNGRCIPTVSSYRCECNMGYKQDAN-GDCIDVDEC-TSNPCTNGD 548
++ ID C + +C G+C+ T Y C C G+ D N +C+DVDEC + C NG
Sbjct: 991 HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGV 1050
Query: 549 CVNTPGSYYCKCHAGFQRTPTKQACI-----DIDECIQNGVLCKNGRCVNTDGSFQCICN 603
C NT G Y C C + +P ++ C+ D+DEC Q+ C+ GRCVN GS++C C
Sbjct: 1051 CENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSYRCECR 1109
Query: 604 AGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ 663
+ G++C + +C ++ G + G P D+C
Sbjct: 1110 PPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG------EDGMCAGPLAGPALTFDDC- 1162
Query: 664 TPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRP----F 719
C G G+ CPP A G C + S + + +P
Sbjct: 1163 ---CCRQG---RGWGAQCRPCPPRGA----GSHCPTSQSESNSFWDTSPLLLGKPPRDED 1212
Query: 720 PGAVTKSECCCAN----PDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG-RDINECAL 774
EC C + P G G C+ CP F S + +D R++N+ L
Sbjct: 1213 SSEEDSDECRCVSGRCVPRPG-GAVCE-CP----GGFQLDASRARCVDIDECRELNQRGL 1266
Query: 775 DPDICANGICENLRGSYRCNCNSGYEPDASGRNCI 809
+C + C N GS+RC C +G+ C+
Sbjct: 1267 ---LCKSERCVNTSGSFRCVCKAGFARSRPHGACV 1298
Score = 130 bits (328), Expect = 1e-29
Identities = 60/167 (35%), Positives = 90/167 (53%), Gaps = 22/167 (13%)
Query: 913 GATLKSECCATLGAAWG-SPCERC----------------ELDTACPRGLARIKGVTCED 955
G T + +CC ++G AWG S C +C E+ CP+G R+ C+D
Sbjct: 296 GLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQD 355
Query: 956 VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQ---CY-LKWDEDE 1011
+NEC + PGVC +G C+N+ GS+ C CP G +L + C+ + E+ C+ L E +
Sbjct: 356 INECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQ 414
Query: 1012 CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
C HP+ + CCC+VG AWG C+ CP GT ++ +CP G G+
Sbjct: 415 CQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGY 461
Score = 97.4 bits (241), Expect = 2e-19
Identities = 59/188 (31%), Positives = 87/188 (46%), Gaps = 38/188 (20%)
Query: 239 CCATIGRAWGHP-CEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVG 297
CC +IG AWG C CP G+ + G VG
Sbjct: 303 CCGSIGTAWGQSKCHKCPQLQYT------------------------GVQKPGPVRGEVG 338
Query: 298 SFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSR 357
+ CP G+K+ +T C+DI+EC++ PG+C G+C N GSY CVCP G+ ++
Sbjct: 339 A---DCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 358 CI---DQRTGMCFSGLVN--GRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEE 412
CI + +CF LV+ +C L R+T+ CCC G+ WG + CP G+
Sbjct: 394 CIADKPEEKSLCFR-LVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARC--QRCPTDGTAA 450
Query: 413 YRRLCMDG 420
++ +C G
Sbjct: 451 FKEICPAG 458
Score = 95.5 bits (236), Expect = 7e-19
Identities = 64/212 (30%), Positives = 84/212 (39%), Gaps = 42/212 (19%)
Query: 188 GRCI---GPNRCAC----VYGFTGPQCE--------RDYRTGPCFTQVNNQ-MCQGQLTG 231
GRC+ G RC C V G +G C+ R C++Q MC G L G
Sbjct: 1095 GRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAG 1154
Query: 232 IVCTKTLCCATIGRAWGHPCEMCPAQ------------------PQPCRRGFIPNIRTGA 273
T CC GR WG C CP + P G P +
Sbjct: 1155 PALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSS 1214
Query: 274 CQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPG---ICE 330
+D DEC+ C G C+ G C CP G + + +C DIDEC + +C+
Sbjct: 1215 EEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCK 1269
Query: 331 TGECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
+ C NT GS+ CVC G+ S C+ QR
Sbjct: 1270 SERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1301
Score = 88.2 bits (217), Expect = 1e-16
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 13/138 (9%)
Query: 652 NGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV--DTHMRSTCYGG 709
N +C D++EC PG+C +G C+N+ GS+RC CPPG ++G C+ +S C+
Sbjct: 349 NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRL 408
Query: 710 IK-KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVG------- 761
+ + C P +T+ CCC + +G CQ CP +A F +C +G G
Sbjct: 409 VSPEHQCQHPLTTRLTRQLCCC-SVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSH 467
Query: 762 --ITVDGRDINECALDPD 777
+T+ G L PD
Sbjct: 468 QTLTIQGESDFSLFLHPD 485
Score = 83.6 bits (205), Expect = 3e-15
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 40/160 (25%)
Query: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINEC 2060
C +GY+ + +C D NEC A+PG C G C N GS+RC+CPPG+ + I +
Sbjct: 341 CPQGYKRL-NSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 2061 DEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN 2120
E+ ++C F+ + P +C P
Sbjct: 399 PEEKSLC-----------FRLVSP-------------------------EHQCQHPLTTR 422
Query: 2121 TTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2160
T+ CCCS G+ WG C+ CP D AF+++CP G G
Sbjct: 423 LTRQLCCCS--VGKAWGARCQRCPTDGTAAFKEICPAGKG 460
Score = 75.9 bits (185), Expect = 6e-13
Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 831 GSYSCTCPPGYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLI 889
G CP GY R + C+DINEC C +G C NN GS+ C C PG L +
Sbjct: 335 GEVGADCPQGYK-RLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 890 CI---DSLKGTCW-LNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELD------T 939
CI K C+ L + +C+ + + CC ++G AWG+ C+RC D
Sbjct: 394 CIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKE 453
Query: 940 ACPRG 944
CP G
Sbjct: 454 ICPAG 458
Score = 71.6 bits (174), Expect = 1e-11
Identities = 61/237 (25%), Positives = 84/237 (35%), Gaps = 44/237 (18%)
Query: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSN--PCTNGDCVNT 552
+D C+ A C GRC+ SYRCEC + +G + E + P C +
Sbjct: 1083 VDECQDPA-ACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQ 1141
Query: 553 PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR--------CVNTDGSFQCICNA 604
G G P + D+C C+ GR C C +
Sbjct: 1142 RGE------DGMCAGPLAGPALTFDDCC-----CRQGRGWGAQCRPCPPRGAGSHCPTSQ 1190
Query: 605 --------------GFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLA 650
G + + D DEC C++G C+ G C C GF L
Sbjct: 1191 SESNSFWDTSPLLLGKPPRDEDSSEEDSDECR----CVSGRCVPRPGGAVCECPGGFQLD 1246
Query: 651 PNGRYCTDVDEC----QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMR 703
+ C D+DEC Q +C + C+N+ GSFRC C G A CV R
Sbjct: 1247 ASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR 1303
Score = 66.2 bits (160), Expect = 4e-10
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 12/122 (9%)
Query: 1087 GKC-RNTIGSFKCRCNSGFALDMEERNCTDI------DECRISPDLCGSGICVNTP--GS 1137
G+C ++T+ C N L +E C I +C P L +G+ P G
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 1138 FECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED 1197
+C +GY+ + +C DI+EC P +CR G C+N GS++C CP GH L PSR
Sbjct: 337 VGADCPQGYKR--LNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1198 CV 1199
C+
Sbjct: 394 CI 395
Score = 64.3 bits (155), Expect = 2e-09
Identities = 44/151 (29%), Positives = 65/151 (43%), Gaps = 25/151 (16%)
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGH-QCELCPLPGTAQYKKICPHGP- 2441
G CF + L ++ L + +CC G WG +C CP QY + GP
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCP---QLQYTGVQKPGPV 333
Query: 2442 ----------GY----TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGT 2487
GY +T +DI+EC MP +C +G C+N GS+RC C G++ S T
Sbjct: 334 RGEVGADCPQGYKRLNSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2488 SCIDLDECSQSPKPCNYICKNTEGSYQCSCP 2518
CI + P+ + + +QC P
Sbjct: 393 QCI-----ADKPEEKSLCFRLVSPEHQCQHP 418
Score = 59.7 bits (143), Expect = 4e-08
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 25/129 (19%)
Query: 1774 KPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIP-----GICANGVCINQI 1828
+PC P PG + CG+I G A +C + P G+ G ++
Sbjct: 287 QPCGSNPLPGLTKQEDCCGSI---------GTAWGQSKCHKCPQLQYTGVQKPGPVRGEV 337
Query: 1829 GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG 1888
G+ +CP G+ + C+DI+EC+ +C R+ DC+N+PGSYRC C G L P+
Sbjct: 338 GA---DCPQGYKRLNSTH-CQDINECAM-PGVC-RHGDCLNNPGSYRCVCPPGHSLGPS- 390
Query: 1889 ACVDRNECL 1897
R +C+
Sbjct: 391 ----RTQCI 395
Score = 55.1 bits (131), Expect = 1e-06
Identities = 52/238 (21%), Positives = 84/238 (35%), Gaps = 46/238 (19%)
Query: 2631 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFS 2690
+ G CPQGY + C D NEC+ P C C N GSY+C CP G S
Sbjct: 333 VRGEVGADCPQGY-KRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR 391
Query: 2691 SAC-----HDVNEC---SSSKNPCNYGCSNTEGGYLC-------------GCPPGYYRVG 2729
+ C + + C S ++ C + + LC CP
Sbjct: 392 TQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAF 451
Query: 2730 QGHCVSGMGFN---KGQYLSLDTEVD------EENALSPEACYECKINGYSKKDSRQKRS 2780
+ C +G G++ Q L++ E D + P+ E +D+ ++R
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2781 IHEPDPTAVEQISLES---------------VDMDSPVNMKFNLSHLGSKEHILELRP 2823
+ P + E+ +S + SP M++ L L +E+ P
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP 569
Score = 54.7 bits (130), Expect = 1e-06
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 512 PTVSSYRCECNMGYKQDANGDCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTK 570
P +C GYK+ + C D++EC C +GDC+N PGSY C C G P++
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR 391
Query: 571 QACI 574
CI
Sbjct: 392 TQCI 395
Score = 53.5 bits (127), Expect = 3e-06
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 1868 INSPGSYRCE----CAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF 1923
+ PG R E C G+K + C D NEC +P VC HG C++ GSY+C+C G
Sbjct: 327 VQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGH 385
Query: 1924 KASQDQTMCMDVDECERHPC 1943
+T C+ E+ C
Sbjct: 386 SLGPSRTQCIADKPEEKSLC 405
Score = 53.1 bits (126), Expect = 4e-06
Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 28/156 (17%)
Query: 718 PFPGAVTKSECCCANPDYGFGEP-CQPCPAKNSAEFHGLCSSG-----VGI--------- 762
P PG +TK E CC + +G+ C CP ++ G+ G VG
Sbjct: 293 PLPG-LTKQEDCCGSIGTAWGQSKCHKCP---QLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 763 -TVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCI---DIDECLVNR 818
+ +DINECA+ P +C +G C N GSYRC C G+ S CI ++ L R
Sbjct: 349 NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFR 407
Query: 819 LLCDNGLCRNTPGS----YSCTCPPGYVFRTETETC 850
L+ C++ + C C G + + C
Sbjct: 408 LVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC 443
Score = 52.0 bits (123), Expect = 9e-06
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 1953 GSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
G C G++ ++ C DI+EC+ VCR+G C N GS++C+C G+ L P
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECA--MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2013 NCI 2015
CI
Sbjct: 393 QCI 395
Score = 48.1 bits (113), Expect = 1e-04
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 175 CGQP-VCENG-CQNGGRCIGPNRCACVYGFT-GP---QC--ERDYRTGPCFTQVNNQ-MC 225
C P VC +G C N G RC C G + GP QC ++ CF V+ + C
Sbjct: 359 CAMPGVCRHGDCLNNP---GSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQC 415
Query: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
Q LT + T+ LCC ++G+AWG C+ CP
Sbjct: 416 QHPLTTRL-TRQLCCCSVGKAWGARCQRCP 444
Score = 47.4 bits (111), Expect = 2e-04
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 554 GSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGK 613
G C G++R + C DI+EC GV C++G C+N GS++C+C G L
Sbjct: 335 GEVGADCPQGYKRLNSTH-CQDINECAMPGV-CRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 614 NCV 616
C+
Sbjct: 393 QCI 395
Score = 43.1 bits (100), Expect = 0.004
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1911 LQGSYQCICHNGFKASQDQTMCMDVDECERHP-CGNGTCKNTVGSYNCLCYPGFEL 1965
++G C G+K + T C D++EC C +G C N GSY C+C PG L
Sbjct: 333 VRGEVGADCPQGYKRL-NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
Score = 40.0 bits (92), Expect = 0.034
Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 30/164 (18%)
Query: 53 GSEGGFLAPEYREEGAA---------------VASRVRR--RGQQDVLRGPNVCGSRFHS 95
G+ GG LAPE R GAA + RV G++ G + RF
Sbjct: 6 GAAGG-LAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKV 64
Query: 96 YCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISS---TCGSKSIQQCSVR 152
P + C+ CR+SC G NM S+ T + C +
Sbjct: 65 VFAP----VICKRTCLKGQCRDSCQQG----SNMTLIGENGHSTDTLTGSGFRVVVCPLP 116
Query: 153 CMNGGTCAD-DHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNR 195
CMNGG C+ + C C + G +C P G GG G +R
Sbjct: 117 CMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSR 160
Score = 37.7 bits (86), Expect = 0.17
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 19/75 (25%)
Query: 149 CSVRCMNGGTCADDHCQCQKGYIGTYCGQP---------------VCENGCQNGGRCIGP 193
C C+ G C D CQ+G T G+ VC C NGG+C
Sbjct: 71 CKRTCLKG-QCRDS---CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSR 126
Query: 194 NRCACVYGFTGPQCE 208
N+C C FTG C+
Sbjct: 127 NQCLCPPDFTGRFCQ 141
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 315 bits (807), Expect = 4e-85
Identities = 364/1393 (26%), Positives = 535/1393 (38%), Gaps = 351/1393 (25%)
Query: 497 ICKHHANLCLNG-RCIP-TVSSYRCECNMGYKQDANGDCIDVDEC-TSNPCTNGDCVN-- 551
+C C NG C+ ++ C+C G+ + C D C + C NG
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQAL 83
Query: 552 --------------TPGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRC-VNTD 595
TP S+ C C GF T + C +++ K GRC +
Sbjct: 84 LPAPLGLPSSPSPLTP-SFLCTCLPGF----TGERCQAKLEDPCPPSFCSKRGRCHIQAS 138
Query: 596 GSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGR 654
G QC C G+ G+ C D C+ N C+NG +C+ +C C PGF G
Sbjct: 139 GRPQCSCMPGWT----GEQCQLRDFCSA-NPCVNGGVCLATYPQIQCHCPPGF----EGH 189
Query: 655 YC-TDVDEC-QTPGICMNG-HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
C DV+EC Q PG C G C N+ GSF+C CP VG +G C ++
Sbjct: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP----VGQEGPRC-----------ELR 234
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSG-VGITVDGRDIN 770
G C P G C+N G CQ P K+S LC G +G
Sbjct: 235 AGPC--PPRG--------CSN-----GGTCQLMPEKDSTFHLCLCPPGFIG--------P 271
Query: 771 ECALDPDICAN------GICENLRGSYRCNCNSGYEPDASGRNCI-DIDEC-LVNRLLCD 822
+C ++PD C + G C++ +Y C C + +G +C D+DEC C
Sbjct: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCR 327
Query: 823 N-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPG 880
N G C+N+ GS+ C C G+ T E++++C + C G+ C + +GSF+C C PG
Sbjct: 328 NGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Query: 881 SKLSSTGLICIDSLKGTCWLN--IQDSRCEVN-INGATLKSECCATLGAAWGSPCERCEL 937
TGL+C L+ C D++C N + G+TL
Sbjct: 385 ----RTGLLC--HLEDMCLSQPCHGDAQCSTNPLTGSTL--------------------- 417
Query: 938 DTACPRGLARIKGVTC-EDVNEC---EVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTG 992
C G + G TC +D++EC + P C + G C+N+ GSF+C CP G TG
Sbjct: 418 -CLCQPGYS---GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TG 469
Query: 993 RVCLDIRMEQCYLKWDEDECI----HPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEY 1048
C + D +EC+ HP G+ C + +
Sbjct: 470 SRC----------EADHNECLSQPCHP------------------GSTCLDL----LATF 497
Query: 1049 ETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDM 1108
LCP G L G+ + NEC + P + + C + + F+C C GF+
Sbjct: 498 HCLCPPG---------LEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFSGTR 547
Query: 1109 EERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM-DIDECERNPL 1167
E DIDECR SP G C + PG+F C+C G+E C ++DEC +P
Sbjct: 548 CEE---DIDECRSSP-CANGGQCQDQPGAFHCKCLPGFEG-----PRCQTEVDECLSDPC 598
Query: 1168 LCRGGTCVNTEGSFQCDCPLGH------------ELSPSREDCVDINECSLSDNLCRNGK 1215
G +C++ G+F C CP G L ++ C D + ++ LC +G
Sbjct: 599 PV-GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKD--QKDKANCLCPDGS 655
Query: 1216 CVNMIGTYQCSCNPGYQATPDRQGCT-DI----DECMIMNGGCDT-------QCTNSEGS 1263
C+C+ G+ R C D+ EC GGC + C
Sbjct: 656 PGCAPPEDNCTCHHGH---CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG 712
Query: 1264 YECSCSEGYALMPDGRSCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT 1322
Y C+C GY G +C+ ++ C + P + +GG C PG Y C C
Sbjct: 713 YNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGP----- 762
Query: 1323 CIDVNECDLNSNICMF------GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAH 1376
+C +++ C+ G C N G+F C C +G+ + C
Sbjct: 763 -----QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPR----CEGKLRPSCADS 813
Query: 1377 NCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCAC 1436
C A+C + P +C C G+ G + + +D C+ C N+ C+ T S+ C C
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTL-MDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
Query: 1437 SEGFTGD--GFTCSDVDECA-----ENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRS 1488
+G+TG S + A + +LC N G C++ +Y C C GF
Sbjct: 871 LQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSL 926
Query: 1489 CQD-IDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCT-DIDECADPINCVNGL 1546
CQD ++ C + TC P + C C GY+ G NC+ ++D C +G
Sbjct: 927 CQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQSQPCHNHGT 982
Query: 1547 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 1606
C PG + C CPP F G+ C + V C L G+ +C++ ++ +
Sbjct: 983 CTPKPGGFHCACPPGF----VGLRC-EGDVDEC-LDQPCHPTGTAACHS-----LANAFY 1031
Query: 1607 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNC 1666
C L G CE +ID C P GG C
Sbjct: 1032 CQCLPGHTGQWCEV-----------------------------EIDPCHSQP-CFHGGTC 1061
Query: 1667 INTFGS---FQCECPQGYYLSEDTRICEDIDEC----FAHPGVCGPG---------TCYN 1710
T GS F C CP+G+ E C H G+C P C +
Sbjct: 1062 EATAGSPLGFICHCPKGF---EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Query: 1711 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 1770
G C+ PP C+ YNG +C C C +
Sbjct: 1119 GYGGPDCLTPPAPKGCGPPSPCL----------YNG-SCSETTGLGGPGFRCSCPH---- 1163
Query: 1771 AWNKPCEPCPTPG 1783
+ P C PG
Sbjct: 1164 --SSPGPRCQKPG 1174
Score = 313 bits (802), Expect = 2e-84
Identities = 330/1205 (27%), Positives = 464/1205 (38%), Gaps = 266/1205 (22%)
Query: 1081 PGMCTY-GKCR-NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 1138
P C+ G+C G +C C G+ + C D C +P + G G+C+ T
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQ----CQLRDFCSANPCVNG-GVCLATYPQI 178
Query: 1139 ECECFEGYESGFMMMKNCMDIDECERNPLLCRGGT-CVNTEGSFQCDCPLGHE------- 1190
+C C G+E D++EC ++P C GT C NT GSFQC CP+G E
Sbjct: 179 QCHCPPGFEGHACER----DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Query: 1191 ----------------LSPSRE---------------DCVDINECSLSDNLCRNG-KCVN 1218
L P ++ DC ++N + + C+NG C +
Sbjct: 235 AGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC-EVNPDNCVSHQCQNGGTCQD 293
Query: 1219 MIGTYQCSCNP---GYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALM 1275
+ TY C C G+ + D C NGG C NS GS+ C C G+
Sbjct: 294 GLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGT---CQNSAGSFHCVCVSGWG-- 348
Query: 1276 PDGRSCAD-IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSN 1334
G SC + +D+C G C + G + CLC G + C L +
Sbjct: 349 --GTSCEENLDDCIA-ATCAPGSTCIDRVGSFSCLCPPGRTGLL----------CHLE-D 394
Query: 1335 ICMFGECENTK--------GSFICHCQLGYSVKKGTTGCTDVDEC---EIGAHNCDMHAS 1383
+C+ C GS +C CQ GYS G T D+DEC + G C+ S
Sbjct: 395 MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS---GPTCHQDLDECLMAQQGPSPCEHGGS 451
Query: 1384 CLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD 1443
CLN PGSF C C G+ G+ + D +EC + C + C++ ++ C C G G
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEA-DHNECLS--QPCHPGSTCLDLLATFHCLCPPGLEGQ 508
Query: 1444 GFTCSDVDECAENINLCENGQCLN------VPGAYRCECEMGFTPASDSRSCQDIDECSF 1497
C N C + CLN + ++C C GF S +R +DIDEC
Sbjct: 509 --------LCEVETNECASAPCLNHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRS 557
Query: 1498 QNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGLCVNTPGRYEC 1556
G C + PG FHC C G+E G C T++DEC V C++ PG + C
Sbjct: 558 SPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFC 613
Query: 1557 NCPPDFQ-------------LNPTGVGCVDNR-VGNCYLKFGPRGDGSLSCNTEIGVG-V 1601
CP F P + C D + NC G G N G
Sbjct: 614 LCPSGFTGQLCEVPLCAPNLCQPKQI-CKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHC 672
Query: 1602 SRSSCCCSLGKAWGNP-CE---------------TCPPVNSTEYYTLCPGGEGFRPNPIT 1645
RSSC C +G W P CE TC P + Y CP G P
Sbjct: 673 QRSSCVCDVG--WTGPECEAELGGCISAPCAHGGTCYP-QPSGYNCTCPTG---YTGP-- 724
Query: 1646 IILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP 1705
E++ C P L GG+C + G + C CP + + D C + P G
Sbjct: 725 TCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSH---TGPQCQTSTDYCVSAPCFNG- 779
Query: 1706 GTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRS--YNGTTCENE-------LPFN 1756
GTC N G ++C+C + G C + C S N TC++ P
Sbjct: 780 GTCVNRPGTFSCLCAMGFQ----GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Query: 1757 VTKRMCCCTYNVGKAWNKPC---EPCPTPGTADFKTICGNIPGFT-----FDIHTGKAVD 1808
T C ++ KPC C G + F +C + G+T + + +
Sbjct: 836 YTGGSCQTLMDL--CAQKPCPRNSHCLQTGPS-FHCLC--LQGWTGPLCNLPLSSCQKAA 890
Query: 1809 IDECKEIPGICAN-GVCINQIGSFRCECPTGFSYNDLLLVCED-IDECSNGDNLCQRNAD 1866
+ + ++ +C N G+C++ S+ C CP GF + +C+D ++ C + CQ A
Sbjct: 891 LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS----LCQDHVNPCES--RPCQNGAT 944
Query: 1867 CINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC------SHGLCVDLQGSYQCICH 1920
C+ P Y C+CA G+ D C + + C +HG C G + C C
Sbjct: 945 CMAQPSGYLCQCAPGY---------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACP 995
Query: 1921 NGFKASQDQTMCMDVDECERHPC---GNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDEC 1977
GF + + DVDEC PC G C + ++ C C PG T ++ID C
Sbjct: 996 PGFVGLRCEG---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGH--TGQWCEVEIDPC 1050
Query: 1978 SSFFGQVC-RNGRCFNEIGS---FKCLCNEGYE--------LTPDGKNCIDTNECVALPG 2025
S Q C G C GS F C C +G+E + +C C+ P
Sbjct: 1051 HS---QPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPK 1107
Query: 2026 SCSPGTCQNLE--GSFRCICPPGYEVKSENCIDINECDEDPNICLF-GSCTNTPG----G 2078
P C L G C+ PP + C P+ CL+ GSC+ T G G
Sbjct: 1108 PGFPPRCACLSGYGGPDCLTPPA----PKGC-------GPPSPCLYNGSCSETTGLGGPG 1156
Query: 2079 FQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGW-G 2137
F+C CP S G RC C +G C CS PG W G
Sbjct: 1157 FRCSCPH----SSPGPRCQKPGAKGCEGRSGDGACDAG-----------CSG-PGGNWDG 1200
Query: 2138 DPCEL 2142
C L
Sbjct: 1201 GDCSL 1205
Score = 300 bits (769), Expect = 1e-80
Identities = 336/1216 (27%), Positives = 476/1216 (39%), Gaps = 320/1216 (26%)
Query: 1696 CFAHPGVCGPG-TCYN-TLGNYTCICPPEYMQVNGGHNCMD----MRKSFCYRSYNGTTC 1749
C + P C G TC + +LG TC C P ++ G C C NG +C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQ---NGGSC 80
Query: 1750 ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
+ LP + P+P T F +C +PGFT + K D
Sbjct: 81 QALLPAPLG-----------------LPSSPSPLTPSF--LCTCLPGFTGERCQAKLED- 120
Query: 1810 DECKEIPGICAN-GVC-INQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC 1867
C P C+ G C I G +C C G++ C+ D CS N C C
Sbjct: 121 -PCP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQ----CQLRDFCSA--NPCVNGGVC 171
Query: 1868 INSPGSYRCECAAGFKLSPNGACV-DRNECLEIPNVCSHGL-CVDLQGSYQCICHNGFKA 1925
+ + +C C GF+ AC D NEC + P C G C + GS+QC+C G
Sbjct: 172 LATYPQIQCHCPPGFE---GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG--- 225
Query: 1926 SQDQTMC-MDVDECERHPCGNG-TCK----NTVGSYNCLCYPGFELTHNNDC-LDIDECS 1978
Q+ C + C C NG TC+ + CLC PGF DC ++ D C
Sbjct: 226 -QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI---GPDCEVNPDNCV 281
Query: 1979 SFFGQVCRNG-RCFNEIGSFKCLCNE---GYELTPDGKNCIDTNECVALPGSCSPGTCQN 2034
S C+NG C + + ++ CLC E G++ + D C E P + GTCQN
Sbjct: 282 S---HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDEC----ETQGPPHCRNGGTCQN 334
Query: 2035 LEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCT------NTPGGFQCLCPPGFV 2088
GSF C+C G+ S C+E+ + C+ +C + G F CLCPPG
Sbjct: 335 SAGSFHCVCVSGWGGTS--------CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG-- 384
Query: 2089 LSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDE 2148
G C + C + +G A+C + + G LC
Sbjct: 385 --RTGLLCH--LEDMCLSQPCHGD-----------AQCSTNPLTGS------TLC----- 418
Query: 2149 VAFQDLCPYGHGTVPSLHDTREDVNECL---ESPGICSNG-QCINTDGSFRCECPMGYNL 2204
LC G+ P+ H +D++ECL + P C +G C+NT GSF C CP GY
Sbjct: 419 -----LCQPGYSG-PTCH---QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY-- 467
Query: 2205 DYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPL 2262
TG RC D +EC + PC G TC +++ +F C C G E G + E NECA P
Sbjct: 468 --TGSRCEADHNEC-LSQPCHPGSTCLDLLATFHCLCPPGLE-GQLCEVET-NECASAPC 522
Query: 2263 LCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI 2322
L C + ++C C G++ + +D+DEC C + G C++ G F C
Sbjct: 523 LNHADCHDLLNGFQCICLPGFS---GTRCEEDIDECRSS--PCANGGQ-CQDQPGAFHCK 576
Query: 2323 CPPGMARRPDGEGCVDE-NECRTKPGICENGR-CVNIIGSYRCECNEGFQSSSSGTECLD 2380
C PG +G C E +EC + P C G C+++ G++ C C GF +G C
Sbjct: 577 CLPGF----EGPRCQTEVDECLSDP--CPVGASCLDLPGAFFCLCPSGF----TGQLC-- 624
Query: 2381 NRQGLCFAEVLQT--ICQMASSSRNLVT----------------------KSECCCDGGR 2416
LC + Q IC+ N + +S C CD G
Sbjct: 625 -EVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVG- 682
Query: 2417 GW-GHQCEL---------CPLPGTAQ-----YKKICPHGPGYTTDGRDIDECKVMPNL-- 2459
W G +CE C GT Y CP G T ++ C P L
Sbjct: 683 -WTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNG 741
Query: 2460 -----------CT------------------------NGQCINTMGSFRCFCKVGYT--- 2481
CT G C+N G+F C C +G+
Sbjct: 742 GSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPR 801
Query: 2482 --------------------------------TDISGTSCIDL-DECSQSPKPCNYICKN 2508
T +G SC L D C+Q P P N C
Sbjct: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ 861
Query: 2509 TEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQ-----------HNCQFLCVNTLGGFTC 2556
T S+ C C +G+ G C L CQ HN LCV++ + C
Sbjct: 862 TGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGG-LCVDSGPSYFC 916
Query: 2557 KCPPGFTQHHTACIDN-NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC-ED 2614
CPPGF + C D+ N C S+P GA C P + C+C G+ G NC ++
Sbjct: 917 HCPPGF--QGSLCQDHVNPCESRPCQNGAT--CMAQPSGYLCQCAPGYD----GQNCSKE 968
Query: 2615 VDECDGNHRCQHG-CQNILGGYRCGCPQGYIQ---HYQWNQCVDENECSNPNACGSASCY 2670
+D C HG C GG+ C CP G++ ++C+D+ C + G+A+C+
Sbjct: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC---HPTGTAACH 1024
Query: 2671 NTLGSYKCACPSGFSFDQFSSACH-DVNECSSSKNPCNYG--CSNTEG---GYLCGCPPG 2724
+ ++ C C G + C +++ C S PC +G C T G G++C CP G
Sbjct: 1025 SLANAFYCQCLPGHT----GQWCEVEIDPCHSQ--PCFHGGTCEATAGSPLGFICHCPKG 1078
Query: 2725 YYRVGQGHCVSGMGFN 2740
+ H GF+
Sbjct: 1079 FEGPTCSHRAPSCGFH 1094
Score = 280 bits (717), Expect = 1e-74
Identities = 355/1378 (25%), Positives = 500/1378 (36%), Gaps = 307/1378 (22%)
Query: 153 CMNGGTC-----ADDHCQCQKGYIGTYCGQP-VCENG--CQNGGRC-------------- 190
C NGGTC CQC G++G C P C+N CQNGG C
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
Query: 191 --IGPN-RCACVYGFTGPQCERDY----------RTGPCFTQVNNQ---MCQGQLTGIVC 234
+ P+ C C+ GFTG +C+ + G C Q + + C TG C
Sbjct: 95 SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC 154
Query: 235 TKTLCCATIGRAWGHPCE---MCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGIC-QG 289
C+ +PC +C A + P AC+ DV+EC PG C +G
Sbjct: 155 QLRDFCSA------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKG 208
Query: 290 GNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSN----------TVG 339
+C NT+GSF+C CP G ++ C + G C CSN
Sbjct: 209 TSCHNTLGSFQCLCPVG----------QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDST 258
Query: 340 SYFCVCPRGYV---TSTDGSRCID---QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
+ C+CP G++ + C+ Q G C GL C C E
Sbjct: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC------------LCPETW 306
Query: 394 RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRP-------GGTGGNGFAPSG 446
W + C +G C +G G SAGS GGT
Sbjct: 307 TGWDCSEDVDECETQGPPH----CRNG---GTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
Query: 447 NGNGYGPGGTGFIPI--------PGGNGF----------SPGVGGAGVGAGGQGPIITGL 488
PG T + PG G P G A +TG
Sbjct: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP----LTGS 415
Query: 489 TIL----NQTIDICKHHANLCL-----------NGRCIPTVSSYRCECNMGYKQDANGDC 533
T+ + C + CL G C+ T S+ C C GY C
Sbjct: 416 TLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---TGSRC 472
Query: 534 -IDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGR 590
D +EC S PC G C++ +++C C G + Q C ++ +EC L +
Sbjct: 473 EADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----GQLCEVETNECASAPCL-NHAD 527
Query: 591 CVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVL 649
C + FQCIC GF G C D DEC ++ G C ++ G+F C C PGF
Sbjct: 528 CHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF-- 581
Query: 650 APNGRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVC-VDTHMRSTCY 707
G C T+VDEC + + C++ G+F C CP G G++C V + C
Sbjct: 582 --EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT----GQLCEVPLCAPNLCQ 635
Query: 708 GGIKKGVCVRPFPGAVTKSECCCANPDYGFGEP-CQPCPAKNSAEFHGLCSSGVGITVDG 766
K +C K+ C C PD G P C P P N HG C + G
Sbjct: 636 ---PKQIC----KDQKDKANCLC--PD---GSPGCAP-PEDNCTCHHGHCQRSSCVCDVG 682
Query: 767 RDINECALDPDICAN------GICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLL 820
EC + C + G C Y C C +GY +G C + +
Sbjct: 683 WTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPC 738
Query: 821 CDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSP 879
+ G C +PG Y CTCPP + T + + C S PC N G C N G+F+C C+
Sbjct: 739 LNGGSCNPSPGGYYCTCPPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAM 795
Query: 880 GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDT 939
G + G C L+ +C DS C N AT + + G C
Sbjct: 796 GFQ----GPRCEGKLRPSC----ADSPCR---NRATCQD-------SPQGPRC------- 830
Query: 940 ACPRGLARIKGVTCEDVNE-CEVFPGVCP-NGRCVNSKGSFHCECPEG-------LTLDG 990
CP G G +C+ + + C P CP N C+ + SFHC C +G L L
Sbjct: 831 LCPTGYT---GGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSS 885
Query: 991 TGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE----CPKPGTK 1046
+ L ++ L + C+ P F C C G G+ C++ C +
Sbjct: 886 CQKAALSQGIDVSSLCHNGGLCVDSGPSYF----CHCPPGFQ-GSLCQDHVNPCESRPCQ 940
Query: 1047 EYETLCPRGAGF-ANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFA 1105
T + +G+ G+ K+++ C++ P +G C G F C C GF
Sbjct: 941 NGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGF- 998
Query: 1106 LDMEERNCTDIDECRISP-DLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECER 1164
+ R D+DEC P G+ C + +F C+C G+ + ++ID C
Sbjct: 999 --VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE----VEIDPCHS 1052
Query: 1165 NPLLCRGGTCVNTEGS---FQCDCPLGHE--LSPSREDCVDINECSLSDNLCRNGKCVNM 1219
P GGTC T GS F C CP G E R + C LC
Sbjct: 1053 QPCF-HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCH-HGGLCLPSPKPGF 1110
Query: 1220 IGTYQCSCNPGY-----QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEG--- 1271
+C+C GY P +GC C + NG C + CSC
Sbjct: 1111 --PPRCACLSGYGGPDCLTPPAPKGCGPPSPC-LYNGSCSETTGLGGPGFRCSCPHSSPG 1167
Query: 1272 -YALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM----KTCIDV 1326
P + C E + CD G C+ G +DG S+ + K C
Sbjct: 1168 PRCQKPGAKGC----EGRSGDGACDAG-CSGPGGN-----WDGGDCSLGVPDPWKGCPSH 1217
Query: 1327 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 1384
+ C L +F + + CH Q D +EC ++C+ +C
Sbjct: 1218 SRCWL-----LFRDGQ-------CHPQ------------CDSEECLFDGYDCETPPAC 1251
Score = 203 bits (516), Expect = 2e-51
Identities = 256/973 (26%), Positives = 350/973 (35%), Gaps = 195/973 (20%)
Query: 128 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQKGYIGTYCGQPV--CE 181
++C C G I C S +C NGGTC D C C + + G C + V CE
Sbjct: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
Query: 182 NG----CQNGGRC---IGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVC 234
C+NGG C G C CV G+ G CE + T C ++ C
Sbjct: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 235 TKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGAC--------------QDVDEC 280
LC H +MC +QP N TG+ QD+DEC
Sbjct: 380 ---LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 281 ---QAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETGE-C 334
Q P C+ GG+C+NT GSF C CP G+ T +CE D +EC P C G C
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQP--CHPGSTC 490
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMTKMQCCCEP 392
+ + ++ C+CP G +G C + T C S L + C L G QC C P
Sbjct: 491 LDLLATFHCLCPPG----LEGQLC-EVETNECASAPCLNHADCHDLLNG----FQCICLP 541
Query: 393 GRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSR--PGGTGGNGFAPSGNG-N 449
G GT C E C +G PG+ + PG G +
Sbjct: 542 GFS---GT---RCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLS 595
Query: 450 GYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHAN----LC 505
P G + +PG F G + P+ L Q ICK + LC
Sbjct: 596 DPCPVGASCLDLPG--AFFCLCPSGFTGQLCEVPLCA--PNLCQPKQICKDQKDKANCLC 651
Query: 506 LNGR--CIPTVSSYRCECNMGYKQDANGDC----------IDVDECTSNPCTN-GDCVNT 552
+G C P + C C+ G+ Q ++ C ++ C S PC + G C
Sbjct: 652 PDGSPGCAPPEDN--CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 553 PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDG 612
P Y C C G+ T C + +G G C + G + C C + G
Sbjct: 710 PSGYNCTCPTGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP----SHTG 761
Query: 613 KNCVDHDECTTTNMCLN-GMCINEDGSFKCICKPGFVLAPNGRYCTDV--DECQTPGICM 669
C + + C N G C+N G+F C+C GF G C C
Sbjct: 762 PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSPCRN 817
Query: 670 NGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECC 729
C +S RC CP G G + +D + C + C++ P C
Sbjct: 818 RATCQDSPQGPRCLCPTGY-TGGSCQTLMDLCAQKPC---PRNSHCLQTGP----SFHCL 869
Query: 730 CANPDYGFGEP--------CQPCPAKNSAEFHGLCSSGVGITVDG--------------- 766
C G+ P CQ + LC +G G+ VD
Sbjct: 870 CLQ---GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG-GLCVDSGPSYFCHCPPGFQGS 925
Query: 767 ---RDINECALDPDICANG-ICENLRGSYRCNCNSGYEPDASGRNCI-DIDECLVNRLLC 821
+N C P C NG C Y C C GY+ G+NC ++D C ++
Sbjct: 926 LCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDAC-QSQPCH 978
Query: 822 DNGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPC---VNGACRNNLGSFNCEC 877
++G C PG + C CPPG+V CE D++EC PC AC + +F C+C
Sbjct: 979 NHGTCTPKPGGFHCACPPGFV----GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC 1034
Query: 878 SPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCEL 937
PG TG C + I + +G T C AT G+ G C
Sbjct: 1035 LPG----HTG--------QWCEVEIDPCHSQPCFHGGT----CEATAGSPLGFICH---- 1074
Query: 938 DTACPRGLARIKGVTCE------DVNEC--------EVFPGVCPNGRCVNSKGSFHCECP 983
CP+G +G TC + C PG P C++ G C P
Sbjct: 1075 ---CPKG---FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Query: 984 EGLTLDGTGRVCL 996
G CL
Sbjct: 1129 PAPKGCGPPSPCL 1141
Score = 166 bits (420), Expect = 3e-40
Identities = 220/891 (24%), Positives = 309/891 (34%), Gaps = 215/891 (24%)
Query: 87 NVCGSRFHSYCCPGW---KTLPGGNQCIVPICR--NSCGDGFCSRPNMCTCSSGQISSTC 141
N GS F+ C PG+ + N+C+ C ++C D + C C G C
Sbjct: 454 NTPGS-FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH--CLCPPGLEGQLC 510
Query: 142 GSKSIQQCSVRCMNGGTCAD----DHCQCQKGYIGTYCGQPVCE---NGCQNGGRCI--- 191
++ + S C+N C D C C G+ GT C + + E + C NGG+C
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 192 GPNRCACVYGFTGPQCERDYR---TGPCFTQVNNQ--------MCQGQLTGIVCTKTLCC 240
G C C+ GF GP+C+ + + PC + +C TG +C LC
Sbjct: 571 GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCA 630
Query: 241 ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
+ + P ++C Q P+ G D C G CQ +C+ VG
Sbjct: 631 PNLCQ----PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
Query: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
C A ++ C P G C Y C CP GY G C +
Sbjct: 686 PECEA------------ELGGCISAP-CAHGGTCYPQPSGYNCTCPTGYT----GPTCSE 728
Query: 361 QRTGMCFSG-LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMD 419
+ T C SG +NG PG C C P T P+ + S +Y C+
Sbjct: 729 EMTA-CHSGPCLNGGSCNPSPG---GYYCTCPPSH-----TGPQC---QTSTDY---CV- 772
Query: 420 GLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAG 479
SA GGT N PG G
Sbjct: 773 ---------SAPCFNGGTCVN---------------------------RPGTFSCLCAMG 796
Query: 480 GQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCID-VDE 538
QGP G + C++ A C + RC C GY G C +D
Sbjct: 797 FQGPRCEGKLRPSCADSPCRNRAT------CQDSPQGPRCLCPTGY---TGGSCQTLMDL 847
Query: 539 CTSNPC-TNGDCVNTPGSYYCKCHAGF------------QRTPTKQACIDIDECIQNGVL 585
C PC N C+ T S++C C G+ Q+ Q ID+ NG
Sbjct: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG-IDVSSLCHNG-- 904
Query: 586 CKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG-MCINEDGSFKCICK 644
G CV++ S+ C C GF+ G C DH + C NG C+ + + C C
Sbjct: 905 ---GLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
Query: 645 PGFVLAPNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMR 703
PG+ +G+ C+ ++D CQ+ +G C G F C CPPG VG+
Sbjct: 958 PGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF-VGL----------- 1001
Query: 704 STCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT 763
C G + EC QPC +A H L ++
Sbjct: 1002 -RCEGDV---------------DECL-----------DQPCHPTGTAACHSLANAFYCQC 1034
Query: 764 VDGRDINECALDPDICAN------GICENLRGS---YRCNCNSGYEPDASGRNCIDIDEC 814
+ G C ++ D C + G CE GS + C+C G+E G C
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPS 1090
Query: 815 LVNRLLCDNGLCRNTPG---SYSCTCPPGYVFRTETETCEDINEC-ESNPCV-NGACRNN 869
GLC +P C C GY + T C +PC+ NG+C
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGPDCLTPPAPKGCGPPSPCLYNGSCSET 1149
Query: 870 LG----SFNCEC---SPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING 913
G F C C SPG + G + G D C+ +G
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSG-------DGACDAGCSG 1193
Score = 71.2 bits (173), Expect = 1e-11
Identities = 102/393 (25%), Positives = 133/393 (33%), Gaps = 100/393 (25%)
Query: 90 GSRFHSYCCPGWKTLPGGNQCIVPI--CRNSC------------GDGFC--SRPN-MCTC 132
G FH C GW G C +P+ C+ + G C S P+ C C
Sbjct: 863 GPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
Query: 133 SSGQISSTCGSKSIQQCSVR-CMNGGTCADDH----CQCQKGYIGTYCGQPV--CENG-C 184
G S C + C R C NG TC CQC GY G C + + C++ C
Sbjct: 919 PPGFQGSLC-QDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
Query: 185 QNGGRCI---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA 241
N G C G CAC GF G +CE D + +Q C T T C
Sbjct: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGD------VDECLDQPCHP-------TGTAACH 1024
Query: 242 TIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINTVGS-- 298
++ A+ C +P C+ ++D C + P GG C T GS
Sbjct: 1025 SLANAFYCQC--------------LPGHTGQWCEVEIDPCHSQP-CFHGGTCEATAGSPL 1069
Query: 299 -FECRCPAGHKQSETTQK--------CEDIDEC--SIIPGICETGECSNTVGSYFCVCPR 347
F C CP G + + + C C S PG C + G C+ P
Sbjct: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
Query: 348 GYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCC---EPG-RCWGIGTIPE 403
S C L NG C++ +C C PG RC G +
Sbjct: 1130 APKGCGPPSPC-----------LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA--K 1176
Query: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGG 436
C R DG G G G+ GG
Sbjct: 1177 GCEGRSG--------DGACDAGCSGPGGNWDGG 1201
Score = 45.8 bits (107), Expect = 6e-04
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 46/184 (25%)
Query: 85 GPNVCGSRFHSYCCPGWKTLPG--GNQCIVPI-------------CRNSCGD--GFCSRP 127
G C S +++ C + LPG G C V I C + G GF
Sbjct: 1019 GTAACHSLANAFYC---QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGF---- 1071
Query: 128 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD-------HCQCQKGYIGTYCGQPVC 180
+C C G TC ++ C +GG C C C GY G C P
Sbjct: 1072 -ICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130
Query: 181 ENGCQNGGRCI------------GPN-RCACVYGFTGPQCERDYRTGPCFTQVNNQMCQG 227
GC C+ GP RC+C + GP+C++ G C + + C
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDGACDA 1189
Query: 228 QLTG 231
+G
Sbjct: 1190 GCSG 1193
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 304 bits (779), Expect = 7e-82
Identities = 374/1457 (25%), Positives = 538/1457 (36%), Gaps = 272/1457 (18%)
Query: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
D++EC+ G C + +C NT GS+ C C GF L + R C I+ C + C
Sbjct: 161 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
Query: 1133 NTPGSFECECFEGY---ESGFMMMKNCMDIDECERNPLLCRGGTCVN----TEGSFQCDC 1185
T C+C G+ E G ++C+ R+P R G+C++ G +C+C
Sbjct: 220 LTITRHRCQCRPGFQLQEDG----RHCV-----RRSPCANRNGSCMHRCQVVRGLARCEC 270
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDID- 1244
+G++L+ + C D++EC+ C +G C+N G+++C C+ GY+ D + C I+
Sbjct: 271 HVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM 329
Query: 1245 ----ECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT 1300
C NGGC C+++ C+C GY L D R+C D+D+C ++P C CT
Sbjct: 330 EIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCT 387
Query: 1301 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 1360
N PG Y C CY G+ S D C DV+EC + C C N GSF C C+ GY + +
Sbjct: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHE 446
Query: 1361 GTTGCTDVDE------CEIGAHNCDMHASCL--NIPGSF----------KCSCR-EGWIG 1401
GC+ ++E E+ H + L +P F + R E +
Sbjct: 447 DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT 506
Query: 1402 NGIKCIDLD---ECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDV---DECAE 1455
C+D +CS C C+ G C C EG+T G C++ D +
Sbjct: 507 EKFVCLDDSFGHDCSLTCDDCRNGGTCL--LGLDGCDCPEGWT--GLICNETCPPDTFGK 562
Query: 1456 NINL---CEN-GQCLNVPGAYRC-------ECEMGFTPASDSRSCQDIDECSFQNIC--V 1502
N + C+N G C +V GA RC CE G + C+ C+ + C +
Sbjct: 563 NCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 1503 FGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP----INCVNGLCVNTPGRYECNC 1558
+G C PG++ C G C++ +C P + +G C G C
Sbjct: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERC 682
Query: 1559 PPDFQLNPTGVGC-----------VDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC- 1606
+ +L G GC D+ G C K P G C E VG +C
Sbjct: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECG-KRCPAGFQGEDCGQECPVGTFGVNCS 741
Query: 1607 -CCSLGKAWGNPCE------TCPPVNSTEYYTL-CPGGE-GFRPNPITIILEDIDECQEL 1657
CS G G PC CPP + E CP G G I + C
Sbjct: 742 SSCSCG---GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 798
Query: 1658 PGLCQGGNCINTFGSFQCE--CPQGYYLSEDTRICEDIDECFAHPGV----CGPG----T 1707
G C C+ F +C+ CP G+Y C ++ HP C PG +
Sbjct: 799 TGACL---CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
Query: 1708 CYNT--LGNYTCICPPEYMQVNGGHNCMDMRKSFCY--RSYNGTTCENELPFN----VTK 1759
C G++ C + GH D C Y G CE + P +
Sbjct: 856 CQRACDTGHWGPDC-SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE 914
Query: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFK-TICGN-IPGFTFDIHTGKAVDIDECKEIPG 1817
+ C C + G A + C P A ++ T C + P F + +C+
Sbjct: 915 QRCQCQH--GAACDHVSGACTCP--AGWRGTFCEHACPAGFFGL---------DCRSACN 961
Query: 1818 ICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCIN----SPGS 1873
A C GS C CP G C + + C + C N P
Sbjct: 962 CTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGHNCSQACACFNGASCDPVH 1015
Query: 1874 YRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 1933
+C CA G+ + P+ CL+ C GL D + C+C NG
Sbjct: 1016 GQCHCAPGW-MGPS--------CLQ---ACPAGLYGD-NCRHSCLCQNG----------- 1051
Query: 1934 DVDECERHPCGNGTCKNTVGSYNCLCYPGFE-LTHNNDCL--DIDECSSFFGQVCRNGRC 1990
GTC G +C C G+ L +CL D+ G G C
Sbjct: 1052 ------------GTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC 1097
Query: 1991 FNEIGSFKCLCNEGYELTPDGKNCID--TNECVALPGSCSPG-TCQNLEGSFRC------ 2041
G +CLC G+ C+ E A SC PG C ++ G+ RC
Sbjct: 1098 DPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTG 1155
Query: 2042 -----ICPPGYEVKSENCIDINECDEDPNIC--LFGSCTNTPG----GFQCLCPPGFVLS 2090
CPPG E+C + +C + C G+C+ G Q CPPG
Sbjct: 1156 SGCEQACPPG--SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP 1213
Query: 2091 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCC---------CSKMPGEGWGDPCE 2141
+ C C + G C P F T C+ + G G G C
Sbjct: 1214 GCEQLCGCLNGGSC--DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC- 1270
Query: 2142 LCPKDDEVAFQDLCPYGHGTV---PSLHDTREDVNECLESPGICSNGQCINTDGSFRCEC 2198
D V LCP G V R V C + + G C ++GS C C
Sbjct: 1271 -----DPVTGTCLCPPGRAGVRCERGCPQNRFGVG-CEHTCSCRNGGLCHASNGS--CSC 1322
Query: 2199 PMGYNLDYTGVRCVDTD-------ECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNC 2251
+G+ + + C ECS N N TC G+ C C GF C
Sbjct: 1323 GLGWTGRHCELACPPGRYGAACHLECSCHN---NSTCEPATGT--CRCGPGFYG---QAC 1374
Query: 2252 EDINECAQNPLLCAFRCMNTFG------SYECTCPIGYALREDQKMCKDLDECAEGLH-- 2303
E + C C G S C CP G+ ++ C+ EG H
Sbjct: 1375 EHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP-GSFGEGCHQR 1433
Query: 2304 -DCESRGMMCKNLIGTFMCICPPGMA---------RRPDGEGCVDENECRTKPGICE--N 2351
DC+ G C + G +C+CPPG + R G C +C C+ +
Sbjct: 1434 CDCDG-GAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGAD-CDPVS 1489
Query: 2352 GRCVNIIGSYRCECNEG 2368
G+C + G C EG
Sbjct: 1490 GQCHCVDGYMGPTCREG 1506
Score = 295 bits (754), Expect = 6e-79
Identities = 415/1640 (25%), Positives = 565/1640 (34%), Gaps = 378/1640 (23%)
Query: 1099 RCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFE-CECFEGYESGFMMMKNC 1156
RC G+ +E C EC S LC G CV PGS + C C G++ C
Sbjct: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQG-----PRC 158
Query: 1157 M-DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK 1215
D+DEC + C+ CVNT GS+ C+C G L C+ IN C+L + C++
Sbjct: 159 QYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH-H 216
Query: 1216 CVNM-IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 1274
CV + I ++C C PG+Q D + C C NG C +C G C C GY L
Sbjct: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 276
Query: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID-----VNEC 1329
DG++C D+DEC C G C N G ++C+C+ G+ D + C VN C
Sbjct: 277 AADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
Query: 1330 DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
+ N+ C G C +T +C C GY + C DVD+C A + C N PG
Sbjct: 336 EANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC---ADSPCCQQVCTNNPG 391
Query: 1390 SFKCSCREGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGF 1445
++C C G+ +G C D+DEC++ C C N GS++C+C G+ D
Sbjct: 392 GYECGCYAGYRLSADGCGCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRR 449
Query: 1446 TCSDVDECAENIN------------------LCENGQCLNVPGAYRCECEM-GFTPASDS 1486
CS ++E +++ L + Q +V GA E E+ G ++
Sbjct: 450 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDV-GADEEEAELRGEHTLTEK 508
Query: 1487 RSCQD----------IDECSFQNICVFGT--CNNLPGMFHCICDDGYELDRTGGNCTDID 1534
C D D+C C+ G C+ G IC++ D G NC+
Sbjct: 509 FVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSC 568
Query: 1535 ECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVG-NCYLKFGPRGDGSLSC 1593
C + G C + G C CPP GC G +C K G C
Sbjct: 569 SCQN-----GGTCDSVTG--ACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG--RC 619
Query: 1594 NTEIGVGVSRSSCCCSLGKAWGNPCE-TCPPVNSTEYYTLCPGGEGFRPNPITIILEDID 1652
+ G +C C G +G C TCPP + PG +
Sbjct: 620 HRLYG------ACLCDPG-LYGRFCHLTCPP------WAFGPGCS--------------E 652
Query: 1653 ECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL 1712
ECQ + Q +C GS C C G+ CE G GPG C+
Sbjct: 653 ECQCVQPHTQ--SCDKRDGS--CSCKAGFRGERCQAECE--------LGYFGPG-CWQ-- 697
Query: 1713 GNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAW 1772
C CP + C C + G C E P T+ V +
Sbjct: 698 ---ACTCPVGVACDSVSGEC----GKRCPAGFQGEDCGQECPVG--------TFGVNCSS 742
Query: 1773 NKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDID--------ECKEIPGICANGV- 1823
+ C P G C PG TG+ + D C+EI C +
Sbjct: 743 SCSCGGAPCHGVTG---QCRCPPG-----RTGEDCEADCPEGRWGLGCQEICPACQHAAR 794
Query: 1824 CINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINS----PGSYRCECA 1879
C + G+ C C GF + C+D+ CQ C N P + C CA
Sbjct: 795 CDPETGA--CLCLPGFVGSR----CQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCA 848
Query: 1880 AGFK-LSPNGACVDRNECLEIPNVCS----HGLCVDLQGSYQCICHNGFKASQDQTMCMD 1934
G+ S AC + + + C+ HG C + G C+C G+ + + C
Sbjct: 849 PGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQ 906
Query: 1935 ---VDECE-RHPCGNG-TCKNTVGSYNC-----------LCYPGFELTHNNDCLDIDECS 1978
CE R C +G C + G+ C C GF DC C+
Sbjct: 907 GHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF---FGLDCRSACNCT 963
Query: 1979 SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG-SCSP--GTCQNL 2035
+ NG C G C E G NC + C G SC P G C
Sbjct: 964 AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNC--SQACACFNGASCDPVHGQCHCA 1021
Query: 2036 EG----SFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSD 2091
G S CP G + +NC C G+C G C CP G+
Sbjct: 1022 PGWMGPSCLQACPAG--LYGDNCRHSCLCQNG------GTCDPVSG--HCACPEGWAGLA 1071
Query: 2092 NGRRCF--DTR-----QSFCFT----NFENGKCSVPKAFNTTKAKCCCSKMPGEGW-GDP 2139
+ C D R C + G+C P + K + C + GW G+
Sbjct: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR----GWFGEA 1127
Query: 2140 CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCE-- 2197
C A + CP G + H C PG +G CE
Sbjct: 1128 C---------AQRCSCPPG----AACHHV---TGACRCPPGFTGSG----------CEQA 1161
Query: 2198 CPMGYNLDYTGVRCVDTDECSIGNPC---GNGTCTNVIGSFECNCNEGFEPGPM-MNCED 2253
CP G G C +C NP GTC+ G +C + PG CE
Sbjct: 1162 CPPG----SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
Query: 2254 INECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCE-SRGMMC 2312
+ C L C G+ C CP G+ + C H C +G C
Sbjct: 1218 LCGC-----LNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
Query: 2313 KNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGI-CENGRCVNIIG---SYRCECNEG 2368
+ GT C+CPPG A G+ CE G N G + C C G
Sbjct: 1271 DPVTGT--CLCPPGRA------------------GVRCERGCPQNRFGVGCEHTCSCRNG 1310
Query: 2369 FQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGW-GHQCELCPL 2427
GLC A + C C G GW G CEL
Sbjct: 1311 ---------------GLCHA-----------------SNGSCSC--GLGWTGRHCELA-- 1334
Query: 2428 PGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRC-------FCKVGY 2480
CP GR C + + N C G+ RC C+
Sbjct: 1335 ---------CP-------PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPC 1378
Query: 2481 TTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQ 2540
G C L C Q PC+ I S +C CP G+ G C+ E +
Sbjct: 1379 PPGFHGAGCQGLCWC-QHGAPCDPI------SGRCLCPAGF----HGHFCERGCEPGSFG 1427
Query: 2541 HNCQFLCVNTLGGFTCK-------CPPGFT-----------QHHTACIDNNECGSQPSLC 2582
C C + GG C CPPG + Q +C + +CG
Sbjct: 1428 EGCHQRC-DCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
Query: 2583 GAKGICQNTPGSFSCECQRG 2602
G C G C+ G
Sbjct: 1487 PVSGQCHCVDGYMGPTCREG 1506
Score = 290 bits (742), Expect = 1e-77
Identities = 380/1508 (25%), Positives = 529/1508 (35%), Gaps = 304/1508 (20%)
Query: 502 ANLCLNG-RCIPTVSSYRCECNMGYKQDANGDC-IDVDEC-TSNPCTNGDCVNTPGSYYC 558
A+LC +G RC+P S+ C C G++ C DVDEC T N CVNTPGSY C
Sbjct: 130 ASLCFHGGRCVPG-SAQPCHCPPGFQGPR---CQYDVDECRTHNGGCQHRCVNTPGSYLC 185
Query: 559 KCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDH 618
+C GF+ + C+ I+ C C++ T +C C GF+L DG++CV
Sbjct: 186 ECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
Query: 619 DECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGH-CINSE 677
C N C G +C C G+ LA +G+ C DVDEC G+ H C+N++
Sbjct: 246 SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA-GLAQCAHGCLNTQ 304
Query: 678 GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF 737
GSF+C C G +G DGR C M G C C++ G
Sbjct: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-----------CSHTSAG- 352
Query: 738 GEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCN 794
P CP G + D R D+++CA P C +C N G Y C
Sbjct: 353 --PLCTCPR------------GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECG 396
Query: 795 CNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDIN 854
C +GY A G C D+DEC +R C++ C N GS+ C+C GY + C +
Sbjct: 397 CYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRLHEDRRGCSPLE 455
Query: 855 ECESN-----PCVNGACR--------------NNLGSFNCECS-PGSKLSSTGLICIDSL 894
E + P V +++G+ E G + +C+D
Sbjct: 456 EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDS 515
Query: 895 KG-TCWLNIQDSRCEVNINGAT--LKSECCATLGAAWGSPC-ERCELDTACPRGLARIKG 950
G C L D R NG T L + C G C E C DT G
Sbjct: 516 FGHDCSLTCDDCR-----NGGTCLLGLDGCDCPEGWTGLICNETCPPDTF---GKNCSFS 567
Query: 951 VTCEDVNECEVFPGVCPNGRCVNSKGSFHCE--CPEGLTLDGTGRVCLDIRMEQCYLKWD 1008
+C++ C+ G C RC +CE CP+G + C +C+ +
Sbjct: 568 CSCQNGGTCDSVTGAC---RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYG 624
Query: 1009 EDECIHPVPGKFRMDAC-CCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTG 1067
C + G+F C A G EC +C +P T+ C + G +
Sbjct: 625 ACLCDPGLYGRFCHLTCPPWAFGPGCSEEC-QCVQPHTQS----CDKRDGSCS------- 672
Query: 1068 RPFYKDINECKA-FPGMCTYGKCRNTIGSF------KCRCNSGFALDMEERNCTDIDECR 1120
CKA F G +C +G F C C G A D C
Sbjct: 673 ---------CKAGFRGERCQAECE--LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAG 721
Query: 1121 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGS 1180
+ CG V T G NC C C G C G
Sbjct: 722 FQGEDCGQECPVGTFG-----------------VNCS--SSCS-----CGGAPCHGVTG- 756
Query: 1181 FQCDCPLGHELSPSREDCVDINECSLSDNLC----RNGKCVNMIGTYQCSCNPGYQATPD 1236
QC CP G DC + +C +C G C C PG+ +
Sbjct: 757 -QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGS-- 811
Query: 1237 RQGCTDIDECMIMNGGCDTQCTNSEGSY------ECSCSEGYALMPDGRSCAD---IDEC 1287
C D+ C T+C+ + + CSC+ G+ R+C +C
Sbjct: 812 --RCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
Query: 1288 ENNPDICDG--GQCTNIPGEYRCLCYDGFMASMDMKTCIDVN---ECDLNSNICMFGECE 1342
++P C G C I G CLC G++ + C + C+ C+
Sbjct: 870 -SHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
Query: 1343 NTKGSFICHCQLGYSVKKGT-------TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
+ G+ C C G+ +GT G +D C A NC A+C + GS C C
Sbjct: 927 HVSGA--CTCPAGW---RGTFCEHACPAGFFGLD-CR-SACNCTAGAACDAVNGS--CLC 977
Query: 1396 REGWIGNGIKCIDLDECSNGTHQCSINAQCVN----TPGSYRCACSEGFTGDGFTCSDV- 1450
G G +C + H CS C N P +C C+ G+ G +C
Sbjct: 978 PAG--RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGP--SCLQAC 1033
Query: 1451 ------DECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDID---ECSFQNIC 1501
D C + LC+NG + P + C C G+ + + C D C C
Sbjct: 1034 PAGLYGDNCRHSC-LCQNGGTCD-PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC 1091
Query: 1502 V-FGTCNNLPGMFHCICDDGYELDRTGGNCTD---IDECADPINCVNG-LCVNTPGRYEC 1556
+ G C+ P C+C G+ D+ C + CA +C G C + G C
Sbjct: 1092 LNGGLCD--PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTG--AC 1147
Query: 1557 NCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGN 1616
CPP F + C G + + +C+ G +C C+ G +
Sbjct: 1148 RCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG------TCSCAAGYHGPS 1201
Query: 1617 PCETCPPVN---STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSF 1673
+ CPP E C G C G C+ C F
Sbjct: 1202 CQQRCPPGRYGPGCEQLCGCLNG---------------GSCDAATGACR---CPTGFLGT 1243
Query: 1674 QCE--CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPP---------- 1721
C CPQG + T +C CG G + + TC+CPP
Sbjct: 1244 DCNLTCPQGRFGPNCTHVCG-----------CGQGAACDPVTG-TCLCPPGRAGVRCERG 1291
Query: 1722 ---EYMQVNGGHNCMDMRKSFCYRS---------YNGTTCENELP---FNVTKRMCCCTY 1766
V H C C+ S + G CE P + + C +
Sbjct: 1292 CPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
Query: 1767 NVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN 1826
N N CE P GT CG PGF G+A + G G+C
Sbjct: 1352 N-----NSTCE--PATGTCR----CG--PGF-----YGQACEHPCPPGFHGAGCQGLCWC 1393
Query: 1827 QIG------SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAA 1880
Q G S RC CP GF + CE E + C + DC G C+
Sbjct: 1394 QHGAPCDPISGRCLCPAGFHGH----FCERGCEPGSFGEGCHQRCDC---DGGAPCDPVT 1446
Query: 1881 GFKLSPNG 1888
G L P G
Sbjct: 1447 GLCLCPPG 1454
Score = 259 bits (661), Expect = 4e-68
Identities = 377/1506 (25%), Positives = 512/1506 (33%), Gaps = 298/1506 (19%)
Query: 1344 TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFK-CSCREGWIGN 1402
T+ + C G+ + GC E A C C +PGS + C C G+
Sbjct: 102 TEARTVLRCCRGWMQQPDEEGCLSA---ECSASLCFHGGRC--VPGSAQPCHCPPGF--Q 154
Query: 1403 GIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINL 1459
G +C D+DEC TH +CVNTPGSY C C GF D TC ++ CA
Sbjct: 155 GPRCQYDVDECR--THNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG 212
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
C++ +RC+C GF D R C C+ +N C + G+ C C
Sbjct: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHV 272
Query: 1520 GYELDRTGGNCTDIDECADPI-NCVNGLCVNTPGRYECNCPPDFQLNPTGVGC--VDNRV 1576
GY+L G C D+DECA + C +G C+NT G ++C C ++L G C ++ +
Sbjct: 273 GYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEI 331
Query: 1577 GNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGG 1636
N SC G G S S G P TCP
Sbjct: 332 VN-------------SCEANNG-GCSHGCSHTSAG-----PLCTCP-------------- 358
Query: 1637 EGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC 1696
G+ + D+D+C + P C C N G ++C C GY LS D CED+DEC
Sbjct: 359 RGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC 416
Query: 1697 FAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF- 1755
+ G C C N G++ C C Y C + + + ELPF
Sbjct: 417 ASSRGGC-EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPM-------VDLDGELPFV 468
Query: 1756 NVTKRMCCCTYNVGKAWNKPC-----EPCPTPG--TADFKTICGNIPGFTFDIHTGKAVD 1808
+ + + + E G T K +C + F D ++
Sbjct: 469 RPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLD-DSFGHDC----SLT 523
Query: 1809 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDI-------DECSNGDNLC 1861
D+C+ G C+ +G C+CP G++ L+C + CS + C
Sbjct: 524 CDDCRN------GGTCL--LGLDGCDCPEGWTG----LICNETCPPDTFGKNCSFSCS-C 570
Query: 1862 QRNADCINSPGSYRC-------ECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGS 1914
Q C + G+ RC C G G C + N + G C L G+
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNCANRGRCHRLYGA 625
Query: 1915 YQCICHNGFKASQDQTMCMD-------VDECERHPCGNGTCKNTVGSYNCLCYPGFELTH 1967
C+C G C +EC+ +C GS C C GF
Sbjct: 626 --CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFR--- 678
Query: 1968 NNDCLDIDECS-SFFGQVCRNG-------RCFNEIGSFKCLCNEGYELTPDGKNCIDTNE 2019
C EC +FG C C + G C G++ G+ C
Sbjct: 679 GERCQA--ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF 736
Query: 2020 CVALPGSCSPG--TCQNLEGSFRCICPPGYEVKSENC-IDINE------CDEDPNICLFG 2070
V SCS G C + G +C CPPG E+C D E C E C
Sbjct: 737 GVNCSSSCSCGGAPCHGVTG--QCRCPPGRT--GEDCEADCPEGRWGLGCQEICPACQHA 792
Query: 2071 SCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSK 2130
+ + G CLC PGFV G RC D + + +CS + A CS
Sbjct: 793 ARCDPETG-ACLCLPGFV----GSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 2131 MPGEGW-GDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICS--NGQC 2187
PG W G C Q C GH H C G C +G C
Sbjct: 848 APG--WTGFSC-----------QRACDTGHWGPDCSHPCN-----CSAGHGSCDAISGLC 889
Query: 2188 INTDGSF--RCE--CPMGYNLDYTGVRCVDTDECSIGNPCGN--GTCTNVIGSFECNCNE 2241
+ G RCE CP G+ G C +C G C + G CT G C
Sbjct: 890 LCEAGYVGPRCEQQCPQGH----FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEH 945
Query: 2242 GFEPGPM-MNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAE 2300
G ++C C C GS C CP G R + +
Sbjct: 946 ACPAGFFGLDCRSACNCTAGAA-----CDAVNGS--CLCPAG---RRGPRCAETCPAHTY 995
Query: 2301 GLHDCES-----RGMMCKNLIGTFMCICPPGMARRPDGEGC---VDENECRTKPGICENG 2352
G H+C G C + G C C PG + C + + CR +C+NG
Sbjct: 996 G-HNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSC-LCQNG 1051
Query: 2353 RCVNIIGSYRCECNEGFQSSSSGTECLDN-------------RQGLCFAEVLQTICQMAS 2399
+ + + C C EG+ + ECL GLC + +C
Sbjct: 1052 GTCDPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW 1110
Query: 2400 SSRNLVTKSECCCDGGRGW-GHQCEL---CPLPGTAQYKKICPHGPGYTTDGRDIDECKV 2455
T +C RGW G C CP PG A C H G C+
Sbjct: 1111 ------TGDKCQSPCLRGWFGEACAQRCSCP-PGAA-----CHHVTG---------ACRC 1149
Query: 2456 MPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQC 2515
P +G C+ G C + +C N C G+ C
Sbjct: 1150 PPGFTGSG------------CEQACPPGSFGEDCAQMCQCPGE----NPACHPATGT--C 1191
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF------TCKCPPGF--TQHHT 2567
SC GY G +C+ C+ LC GG C+CP GF T +
Sbjct: 1192 SCAAGY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL 1247
Query: 2568 ACIDNN---------ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC 2618
C CG + G C PG C+RG + G+ CE C
Sbjct: 1248 TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC 1307
Query: 2619 DGN---HRCQHGCQNILG--GYRC--GCPQGYIQHYQWNQCVDENECSNPNACGSASCYN 2671
H C LG G C CP G +C N + A G+ C
Sbjct: 1308 RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGP 1367
Query: 2672 TLGSYKC--ACPSGFSFDQFSSACHDVNECSSSK--NPCNYGCSNTEG--GYLC--GCPP 2723
C CP GF + C + C +P + C G G+ C GC P
Sbjct: 1368 GFYGQACEHPCPPGF----HGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP 1423
Query: 2724 GYYRVG 2729
G + G
Sbjct: 1424 GSFGEG 1429
Score = 251 bits (641), Expect = 7e-66
Identities = 375/1572 (23%), Positives = 511/1572 (32%), Gaps = 347/1572 (22%)
Query: 178 PVCENGCQNGGRCIGPNRCACVY-GFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTK 236
PV + GC C+G R Y G+ C Q + C+
Sbjct: 71 PVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA 130
Query: 237 TLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINT 295
+LC H P QPC P + CQ DVDEC+ G CQ C+NT
Sbjct: 131 SLCF--------HGGRCVPGSAQPCHCP--PGFQGPRCQYDVDECRTHNGGCQH-RCVNT 179
Query: 296 VGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDG 355
GS+ C C G + ++ C I+ C++ G C+ T+ + C C G+ DG
Sbjct: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
Query: 356 SRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRR 415
C+ R C + NG C +C C G +
Sbjct: 240 RHCV--RRSPCANR--NGSCMHRCQVVRGLARCECHVG--------------------YQ 275
Query: 416 LCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAG 475
L DG + A G A +G G V AG
Sbjct: 276 LAADGKACEDVDECAA---------GLAQCAHG------------CLNTQGSFKCVCHAG 314
Query: 476 VGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDAN-GDCI 534
G G + + + ++ C+ + C +G C T + C C GY+ D + CI
Sbjct: 315 YELGADGRQCYRIEM--EIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 371
Query: 535 DVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNT 594
DVD+C +PC C N PG Y C C+AG++ + C D+DEC + C++ C N
Sbjct: 372 DVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNL 430
Query: 595 DGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFV------ 648
GSFQC C AG+ L D + C +E ++ DG + +
Sbjct: 431 AGSFQCSCEAGYRLHEDRRGCSPLEE----------PMVDLDGELPFVRPLPHIAVLQDE 480
Query: 649 ---LAPNGRYCTDVDECQTPG-ICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
L + D +E + G + + + SF DC C D
Sbjct: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDC---------SLTCDDCRNGG 531
Query: 705 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 764
TC G+ C + G + C P FG+ C F C +G
Sbjct: 532 TCLLGLDGCDCPEGWTGLICNETC----PPDTFGKNC---------SFSCSCQNG----- 573
Query: 765 DGRDINECALDPDICANGICENLRGSYRC-------NCNSGYEPDASGRNCIDIDECLVN 817
G C+++ G+ RC NC G G++C C N
Sbjct: 574 -----------------GTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNC-AN 615
Query: 818 RLLCDN--GLCRNTPGSYS----CTCPPGYVFRTETETCEDIN-ECESNPCVNGACRNNL 870
R C G C PG Y TCPP +E C+ + +S +G+C
Sbjct: 616 RGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKA 675
Query: 871 GSFNCECSPGSKLSSTGLIC-----------IDSLKGTCWLNIQDSRCEVNINGATLKSE 919
G C +L G C DS+ G C RC G E
Sbjct: 676 GFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGEC-----GKRCPAGFQGEDCGQE 730
Query: 920 C--------CATLGAAWGSPC---------------ERCELDTACPRGLARIKGVTCEDV 956
C C++ + G+PC E CE D CP G G+ C+++
Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEAD--CPEGR---WGLGCQEI 785
Query: 957 --------------NECEVFPG--------VCPNG----------RCVNS----KGSFHC 980
C PG VCP G C N + HC
Sbjct: 786 CPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC 845
Query: 981 ECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV---PGKFRMDA----CCCAVGAAW 1033
C G T R C D W D C HP G DA C C G
Sbjct: 846 SCAPGWTGFSCQRAC-DTG------HWGPD-CSHPCNCSAGHGSCDAISGLCLCEAGYV- 896
Query: 1034 GTECE-ECPK----PGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK 1088
G CE +CP+ PG E C GA + T ++ A P
Sbjct: 897 GPRCEQQCPQGHFGPGC-EQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLD 955
Query: 1089 CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPG---SFECECFEG 1145
CR+ C C +G A D +C R P C +T G S C CF G
Sbjct: 956 CRSA-----CNCTAGAACDAVNGSCL-CPAGRRGP-RCAETCPAHTYGHNCSQACACFNG 1008
Query: 1146 ----------YESGFMMMKNCMDI-------DECERNPLLCRGGTCVNTEGSFQCDCPLG 1188
+ + M +C+ D C + L GGTC G C CP G
Sbjct: 1009 ASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG--HCACPEG 1066
Query: 1189 HELSPSREDCV--DINE-CSLSDNLCRNGKCVNMIGTYQCSCNPGY-------------- 1231
++C+ D+ C S G C G +C C G+
Sbjct: 1067 WAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWF 1124
Query: 1232 -QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENN 1290
+A R C C + G C + E +C G G CA + +C
Sbjct: 1125 GEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPG----SFGEDCAQMCQCPGE 1180
Query: 1291 PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN---ECDLNSNICMFGECENTKGS 1347
C P C C G+ + C C+ G C+ G+
Sbjct: 1181 NPACH-------PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
Query: 1348 FICHCQLGY-------SVKKGTTG--CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
C C G+ + +G G CT V C GA + +CL PG C G
Sbjct: 1234 --CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG 1291
Query: 1399 WIGN--GIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD-----------GF 1445
N G+ C C NG C + GS C+C G+TG G
Sbjct: 1292 CPQNRFGVGCEHTCSCRNG-------GLCHASNGS--CSCGLGWTGRHCELACPPGRYGA 1342
Query: 1446 TCSDVDECAENINLCE--NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC-- 1501
C C N + CE G C PG Y CE P CQ + C C
Sbjct: 1343 ACHLECSCHNN-STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDP 1401
Query: 1502 VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC--ADPINCVNGLCVNTPGRYECNCP 1559
+ G C G C+ G E G C +C P + V GLC+ PGR C
Sbjct: 1402 ISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN 1461
Query: 1560 PDFQLNPTGVGC 1571
D + G C
Sbjct: 1462 LDCRRGQFGPSC 1473
Score = 158 bits (400), Expect = 6e-38
Identities = 360/1518 (23%), Positives = 490/1518 (32%), Gaps = 359/1518 (23%)
Query: 119 CGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH---CQCQKGYIGTYC 175
C G+ +P+ C S + S++ C +GG C C C G+ G C
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASL-----------CFHGGRCVPGSAQPCHCPPGFQGPRC 158
Query: 176 GQPVCENGCQNGG---RCI---GPNRCACVYGFTGPQCERDYRTGPCFTQ--VNNQMCQG 227
V E NGG RC+ G C C GF + D RT + N CQ
Sbjct: 159 QYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF---RLHTDSRTCLAINSCALGNGGCQH 215
Query: 228 QLTGIVCTKTLC--------------------CATIGRAWGHPCEMCPAQPQ-PCRRGFI 266
+ T+ C CA + H C++ + C G+
Sbjct: 216 HCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQ 275
Query: 267 PNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHK------------------ 308
AC+DVDEC A C G C+NT GSF+C C AG++
Sbjct: 276 LAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNS 334
Query: 309 ---------------------------QSETTQK-CEDIDECSIIPGICETGECSNTVGS 340
+ +T Q+ C D+D+C+ P C C+N G
Sbjct: 335 CEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGG 392
Query: 341 YFCVCPRGYVTSTDGSRCID------QRTGM---CFSGLVNGRCAQELPGRMTKMQCCCE 391
Y C C GY S DG C D R G C + + +C+ E R+ + + C
Sbjct: 393 YECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCS 452
Query: 392 P---------GRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGF 442
P G + +P ++ +E +L D +G A R T F
Sbjct: 453 PLEEPMVDLDGELPFVRPLPHIAVLQ--DELPQLFQDD-DVGADEEEAELRGEHTLTEKF 509
Query: 443 APSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHA 502
+ G+ T GG G+ G G G +I T T +
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGGTCLL-GLDGCDCPEGWTG-LICNETCPPDTFGKNCSFS 567
Query: 503 NLCLNG----------RCIPTVSSYRCE--CNMGY-----KQDANGDCIDVDECTSNPCT 545
C NG RC P VS CE C GY ++ N C + C
Sbjct: 568 CSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCN--CANRGRCHR---L 622
Query: 546 NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAG 605
G C+ PG Y CH C + +C+Q C DGS C C AG
Sbjct: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP----HTQSCDKRDGS--CSCKAG 676
Query: 606 FELTTDGKNCVDHDE-------CTTTNMCLNGM-CINEDGSFKCICKPGFVLAPNGRYC- 656
F G+ C E C C G+ C + G C GF G+ C
Sbjct: 677 FR----GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECP 732
Query: 657 --TDVDECQTPGICMNGHCINSEGSFRC-----------DCPPGLAVGMDGRVCVDTHMR 703
T C + C C G RC DCP G +C
Sbjct: 733 VGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHA 792
Query: 704 STCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQP-CPAKNSAEFH---GLCSSG 759
+ C +C+ F G+ + C P +G CQ C N H G CS
Sbjct: 793 ARCDPETGACLCLPGFVGSRCQDVC----PAGWYGPSCQTRCSCANDGHCHPATGHCSCA 848
Query: 760 VGITV--------DGRDINECALDPDICA--NGICENLRGSYRCNCNSGYEPDASGRNCI 809
G T G +C+ P C+ +G C+ + G C C +GY + C
Sbjct: 849 PGWTGFSCQRACDTGHWGPDCS-HPCNCSAGHGSCDAISGL--CLCEAGYVGPRCEQQCP 905
Query: 810 D--IDECLVNRLLCDNGL-CRNTPGSYSCTCPPGY------------VFRTETETCEDIN 854
R C +G C + G+ CTCP G+ F + + +
Sbjct: 906 QGHFGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
Query: 855 ECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC-----------IDSLKGTC----- 898
+ VNG+C G C+ + G C D + G C
Sbjct: 964 AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPG 1023
Query: 899 WLNIQDSR-CEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVN 957
W+ + C + G + C G C+ ACP G A G+ CE
Sbjct: 1024 WMGPSCLQACPAGLYGDNCRHSCLCQNGGT----CDPVSGHCACPEGWA---GLACE--K 1074
Query: 958 EC---EVFPGVCPNGRCVNS----KGSFHCECPEGLTLDGTGRVCL-----DIRMEQCYL 1005
EC +V G +G C+N + C CP G T D CL + ++C
Sbjct: 1075 ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRC-- 1132
Query: 1006 KWDEDECIHPVPGKFRMDACCCAVG------------AAWGTECEE---CP--KPGTKEY 1048
H V G AC C G ++G +C + CP P
Sbjct: 1133 SCPPGAACHHVTG-----ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPA 1187
Query: 1049 ETLCPRGAGFANRGDVLTGR-PFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALD 1107
C AG+ G R P + C+ G G C G+ CRC +GF
Sbjct: 1188 TGTCSCAAGY--HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGT 1243
Query: 1108 MEERNCTDIDECRISPDL-----CGSGICVNTPGSFECECFEGYESGFMMMKNCMDID-- 1160
C + R P+ CG G + P + C C G +G + C
Sbjct: 1244 DCNLTCP---QGRFGPNCTHVCGCGQGAACD-PVTGTCLCPPG-RAGVRCERGCPQNRFG 1298
Query: 1161 -ECERNPLLCRGGTCVNTEGSFQCDCPLGH-----ELS--PSREDCVDINECSLSDNLCR 1212
CE GG C + GS C C LG EL+ P R ECS +N
Sbjct: 1299 VGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNN--- 1353
Query: 1213 NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY 1272
C GT C C PG+ Q C GC C G+ C G
Sbjct: 1354 -STCEPATGT--CRCGPGFYG----QACEHPCPPGFHGAGCQGLCWCQHGA-PCDPISGR 1405
Query: 1273 ALMPDG-------RSCADI---DECENNPDICDGGQ-CTNIPGEYRCLCYDGFMASMDMK 1321
L P G R C + C D CDGG C + G CLC G +
Sbjct: 1406 CLCPAGFHGHFCERGCEPGSFGEGCHQRCD-CDGGAPCDPVTG--LCLCPPGRSGAT--- 1459
Query: 1322 TCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD-M 1380
C+L+ FG S HC G G +CD +
Sbjct: 1460 -------CNLDCRRGQFGP------SCTLHCDCG------------------GGADCDPV 1488
Query: 1381 HASCLNIPGSFKCSCREG 1398
C + G +CREG
Sbjct: 1489 SGQCHCVDGYMGPTCREG 1506
Score = 152 bits (385), Expect = 4e-36
Identities = 252/1076 (23%), Positives = 339/1076 (31%), Gaps = 212/1076 (19%)
Query: 577 DECIQNGVLCKNGR--CVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC--LNGMC 632
D+C +NG C G C +G ICN T GKNC C C + G C
Sbjct: 525 DDC-RNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
Query: 633 INEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGIC--MNGHCINSEGSF----RCDCPP 686
G C+ G G++C C G C + G C+ G + CPP
Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 687 -GLAVGMDGRV-CVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPC 744
G CV H +S C C F G ++EC G + C C
Sbjct: 644 WAFGPGCSEECQCVQPHTQS-CDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACT-C 701
Query: 745 PAKNSAE-FHGLCSSGVGITVDGRDIN-ECAL--------DPDICANGICENLRGSYRC- 793
P + + G C G D EC + C C + G RC
Sbjct: 702 PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCP 761
Query: 794 ------NCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTET 847
+C + G C +I + CD P + +C C PG+V
Sbjct: 762 PGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD-------PETGACLCLPGFV----G 810
Query: 848 ETCEDI-------NECESN-PCVN-GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTC 898
C+D+ C++ C N G C G +C C+PG TG C
Sbjct: 811 SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGW----TGFSC-------- 856
Query: 899 WLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNE 958
C+ G C + G C+ C G G CE
Sbjct: 857 -----QRACDTGHWGPDCSHPCNCSAGHG---SCDAISGLCLCEAGYV---GPRCEQQ-- 903
Query: 959 CEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVP- 1017
CP G C+C G D C C W C H P
Sbjct: 904 -------CPQGH-FGPGCEQRCQCQHGAACDHVSGACT------CPAGWRGTFCEHACPA 949
Query: 1018 GKFRMD---ACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDI 1074
G F +D AC C GAA C LCP G + + +
Sbjct: 950 GFFGLDCRSACNCTAGAACDAVNGSC----------LCPAGRRGPRCAETCPAHTYGHNC 999
Query: 1075 NE-CKAFPGMC---TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 1130
++ C F G +G+C G C + NC C+ G
Sbjct: 1000 SQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQ------NGGT 1053
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDE---CERNPLLCRGGTCVNTEGSFQCDCPL 1187
C P S C C EG+ +G K C+ D C + GG C G +C CP
Sbjct: 1054 C--DPVSGHCACPEGW-AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPA 1108
Query: 1188 GHELSPSREDCVD--INECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDI-- 1243
G + C+ E C G + + T C C PG+ + Q C
Sbjct: 1109 GWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHV-TGACRCPPGFTGSGCEQACPPGSF 1167
Query: 1244 -DEC--MIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI-------DECENNPDI 1293
++C M G + C + G+ CSC+ GY G SC CE
Sbjct: 1168 GEDCAQMCQCPGENPACHPATGT--CSCAAGY----HGPSCQQRCPPGRYGPGCEQLCGC 1221
Query: 1294 CDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGE---CENTKGSFIC 1350
+GG C G C C GF+ + TC +++C G+ C+ G+ +C
Sbjct: 1222 LNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLC 1279
Query: 1351 -------HCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNG 1403
C+ G + GC C G HAS + CSC GW G
Sbjct: 1280 PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL---CHAS------NGSCSCGLGWTGRH 1330
Query: 1404 IKCIDLDECSNGTH--QCSINAQCVNT----PGSYRCACSEGFTGD-----------GFT 1446
+ C G + C + C N P + C C GF G G
Sbjct: 1331 CELA----CPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG 1386
Query: 1447 CSDVDECAENINLCE--NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC--V 1502
C + C C+ +G+CL G + CE G P S C +C C V
Sbjct: 1387 CQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPV 1445
Query: 1503 FGTCNNLPGM-------------------FHCICDDGYELDRTGGNCTDIDECADP 1539
G C PG HC C G + D G C +D P
Sbjct: 1446 TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGP 1501
Score = 119 bits (299), Expect = 3e-26
Identities = 196/756 (25%), Positives = 248/756 (32%), Gaps = 168/756 (22%)
Query: 107 GNQCIVPICRNSCGDGFCS-RPNMCTCSSGQISSTC---------GSKSIQQCSVRCMNG 156
G Q I P C+++ C C C G + S C G +CS C N
Sbjct: 781 GCQEICPACQHAAR---CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS--CAND 835
Query: 157 GTC--ADDHCQCQKGYIGTYCGQPVCENG-----------CQNG-GRCIG-PNRCACVYG 201
G C A HC C G+ G C Q C+ G C G G C C C G
Sbjct: 836 GHCHPATGHCSCAPGWTGFSC-QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAG 894
Query: 202 FTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW-GHPCE-MCPAQPQ 259
+ GP+CE+ G F Q CQ Q G C T W G CE CPA
Sbjct: 895 YVGPRCEQQCPQGH-FGPGCEQRCQCQ-HGAACDHVSGACTCPAGWRGTFCEHACPA--- 949
Query: 260 PCRRGFIPNIRTGACQDV--DECQAIPGIC------QGGNCINTVGSFECRCPA---GHK 308
GF AC C A+ G C +G C T CPA GH
Sbjct: 950 ----GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET-------CPAHTYGHN 998
Query: 309 QSETT-----QKCEDI-DECSIIPG-----------------------ICETGECSNTVG 339
S+ C+ + +C PG +C+ G + V
Sbjct: 999 CSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVS 1058
Query: 340 SYFCVCPRGYVTSTDGSRCI--DQRTGMCFS-GLVNGRCAQELPGRMTKMQCCCEPG--- 393
+ C CP G+ C+ D R G S G +NG GR C C G
Sbjct: 1059 GH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR-----CLCPAGWTG 1112
Query: 394 -RCWG---IGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGN 449
+C G EAC R S C G + G+ PG T G+G +
Sbjct: 1113 DKCQSPCLRGWFGEACAQRCS------CPPGAACHHVTGACRCPPGFT-GSGCEQACPPG 1165
Query: 450 GYGPGGTGFIPIPGGN-GFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNG 508
+G PG N P G AG GP + C+ G
Sbjct: 1166 SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
Query: 509 RCIPTVSSYRC-------ECNMGYKQDANG-DCIDVDEC----TSNPCTNGDCVNTPGSY 556
C + RC +CN+ Q G +C V C +P T G C+ PG
Sbjct: 1226 SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVT-GTCLCPPGRA 1284
Query: 557 YCKCHAGFQRTPTKQACIDIDECIQNGVLC--KNGRCVNTDGSFQCICNAGFELTTDGKN 614
+C G + C C +NG LC NG C G C G
Sbjct: 1285 GVRCERGCPQNRFGVGCEHTCSC-RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAA 1343
Query: 615 CVDHDECTTTNMCLNGMCINEDGSFKC-----------ICKPGFVLAPNGRYCTDVDECQ 663
C H EC+ N N C G+ +C C PGF +G C + CQ
Sbjct: 1344 C--HLECSCHN---NSTCEPATGTCRCGPGFYGQACEHPCPPGF----HGAGCQGLCWCQ 1394
Query: 664 TPGIC--MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK----KGVCVR 717
C ++G C+ G C G G G C H R C GG G+C+
Sbjct: 1395 HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGC---HQRCDCDGGAPCDPVTGLCLC 1451
Query: 718 P--FPGAVTKSEC--------CCANPDYGFGEPCQP 743
P GA +C C + D G G C P
Sbjct: 1452 PPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDP 1487
Score = 82.4 bits (202), Expect = 6e-15
Identities = 82/298 (27%), Positives = 106/298 (35%), Gaps = 69/298 (23%)
Query: 97 CCPGWKTLPGGNQCIVPICRNSC--GDGFCSRP--------NMCTCSSGQISSTCGSKSI 146
C PG++ C+ NSC G+G C + C C G G +
Sbjct: 187 CKPGFRLHTDSRTCLAI---NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
Query: 147 QQCSVRCMN-GGTCADD--------HCQCQKGYI----GTYC--------GQPVCENGCQ 185
++ C N G+C C+C GY G C G C +GC
Sbjct: 244 RRSP--CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCL 301
Query: 186 NGGRCIGPNRCACVYGFT----GPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA 241
N G +C C G+ G QC R + NN C
Sbjct: 302 NTQ---GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS--------------- 343
Query: 242 TIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
H C A P C RG+ + C DVD+C P C C N G +E
Sbjct: 344 -------HGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYE 394
Query: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
C C AG++ S CED+DEC+ G CE C+N GS+ C C GY D C
Sbjct: 395 CGCYAGYRLSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 40.0 bits (92), Expect = 0.034
Identities = 44/152 (28%), Positives = 48/152 (31%), Gaps = 22/152 (14%)
Query: 89 CGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQ 148
C FH C G G C R C GF C G C Q+
Sbjct: 1378 CPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH----QR 1433
Query: 149 CSVRCMNGGTC--ADDHCQCQKGYIGTYC------GQ--PVCENGCQ-NGGRCIGP--NR 195
C C G C C C G G C GQ P C C GG P +
Sbjct: 1434 CD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
Query: 196 CACVYGFTGPQCERDYRTGPCFTQVNNQMCQG 227
C CV G+ GP C GP N + QG
Sbjct: 1492 CHCVDGYMGPTCREG---GPLRLPENPSLAQG 1520
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 276 bits (706), Expect = 2e-73
Identities = 230/761 (30%), Positives = 313/761 (41%), Gaps = 161/761 (21%)
Query: 1026 CCAVGAAW---GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG 1082
CCA G W EC E P+ GT++ N C+
Sbjct: 445 CCAAGQQWAIDNDECLEIPESGTED---------------------------NVCRTAQR 477
Query: 1083 MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRIS-----PDLCGSGICVNTPG- 1136
C C + + C A + E D D C IS D CG G+ V G
Sbjct: 478 HC----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
Query: 1137 SFECECFEGYESGFMMMKNC-----MDIDECERNPLLCRGGTCVN-TEGSFQCDCPLGHE 1190
S E GY +M+ C + + E R P V+ E + + LG E
Sbjct: 534 SCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTE 593
Query: 1191 LS-PSREDCVDINEC-SLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-------- 1240
P+ D +EC L LC++ C+N +G+Y C+C PG+ D + C
Sbjct: 594 AELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
Query: 1241 -------------TDIDECMIM-----------NGGCDTQCTNSEGSYECSCSEGYALMP 1276
+ + I NG C C+ GS CSC GYA+M
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
Query: 1277 DGRSCADIDECENNPDICDGGQ-CTNIPGEYRC-----LCYDGFMASMDMKTCIDVNECD 1330
DG SC D DEC C Q C N G + C LC DG++ + K C+D+NEC
Sbjct: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECV 771
Query: 1331 LNSNICMFGE-CENTKGSFICH----CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
+ + C GE C NT GSF C+ C+ GY++K G C DVDEC +G H C C
Sbjct: 772 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQ 829
Query: 1386 NIPGSFKCS----CREGWI----GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC--- 1434
N GSF C C +G++ GN C+D++EC++ + C C+NT GSY C
Sbjct: 830 NTKGSFYCQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRN 886
Query: 1435 --ACSEGF--TGDGFTCSDVDECAENINLCENGQ-CLNVPGAYRCECEMGFTPASDSRSC 1489
C+ G+ + DG C DV+EC ++ C GQ C N+PG+YRC+C+ GF + R C
Sbjct: 887 PLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC 946
Query: 1490 QDIDEC--SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLC 1547
D++EC S +C TC N G + C C G+ L G C D++EC + C + C
Sbjct: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRC-SQEC 1003
Query: 1548 VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCC 1607
N G Y+C C +QL G C D + C +G G L + V S C
Sbjct: 1004 ANIYGSYQCYCRQGYQLAEDGHTCTD--IDEC-----AQGAGILCTFRCLNVPGSYQCAC 1056
Query: 1608 CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC-QGGNC 1666
G YT+ G +D+DEC C + C
Sbjct: 1057 PEQG------------------YTMTANGRS---------CKDVDECALGTHNCSEAETC 1089
Query: 1667 INTFGSFQC---ECPQGYYLSEDTR----ICEDIDECFAHP 1700
N GSF+C ECP Y T+ C D EC P
Sbjct: 1090 HNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
Score = 260 bits (664), Expect = 2e-68
Identities = 223/780 (28%), Positives = 313/780 (40%), Gaps = 171/780 (21%)
Query: 1878 CAAGFKLSPNGACVDRNECLEIP------NVC---SHGLCVDLQGSYQCICHNGFKASQD 1928
CAAG + + +D +ECLEIP NVC CV C+ G +++
Sbjct: 446 CAAGQQWA-----IDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKE 498
Query: 1929 QTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG 1988
C D CG + Y C DC + GQ C +
Sbjct: 499 GETCGAEDN---DSCG-------ISLYKQCC----------DCCGLGLRVRAEGQSCESN 538
Query: 1989 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG-------SCSPGTCQNLEGSFRC 2041
N GY +C + E + +P + +P E + R
Sbjct: 539 P------------NLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGRE 586
Query: 2042 ICPPGYEVKSENCI---DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
G E + N + D +EC P C NT G + C C PGF L D+GR C
Sbjct: 587 ALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP 646
Query: 2099 TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG 2158
G P + + +
Sbjct: 647 E-------------------------------------GHPPQPEAPQEPALKSEFSQVA 669
Query: 2159 HGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECS 2218
T+P N C ++ G C C GS C C GY + GV C D DEC
Sbjct: 670 SNTIPL---PLPQPNTCKDN-GPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
Query: 2219 IG-NPCGNGT-CTNVIGSFEC-----NCNEGFEPGPMMNCEDINECAQNPLLCA--FRCM 2269
+G + C C N +GSF C C +G+ C DINEC + C+ C+
Sbjct: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCV 784
Query: 2270 NTFGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC---- 2321
NT GS+ C TC GYAL++ + C+D+DECA G H C+ G +C+N G+F C
Sbjct: 785 NTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQ 841
Query: 2322 ICPPGMARRPDGEGCVDENECRTKPGICENG-RCVNIIGSYRCE-----CNEGFQSSSSG 2375
C G + P+G CVD NEC + C G C+N +GSY C+ C G+ +S G
Sbjct: 842 RCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 2376 TECLDNRQGLCFAEVLQ----TIC---------------QMASSSRNLVTKSECCCDGGR 2416
T+C+D + C V + +C Q + R + +EC GR
Sbjct: 901 TKCVDVNE--CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 958
Query: 2417 GWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNGQCINTMGSFR 2473
H CE Y+ C G DG+ D++EC+ C+ +C N GS++
Sbjct: 959 LCQHTCE----NTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQ 1011
Query: 2474 CFCKVGYTTDISGTSCIDLDECSQSPK-PCNYICKNTEGSYQCSCP-RGYVLQEDGKTCK 2531
C+C+ GY G +C D+DEC+Q C + C N GSYQC+CP +GY + +G++CK
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1071
Query: 2532 DLDECQTKQHNCQ--FLCVNTLGGFTC---KCPPGFTQ------HHTACIDNNECGSQPS 2580
D+DEC HNC C N G F C +CPP + Q T C D EC + P+
Sbjct: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPA 1131
Score = 260 bits (664), Expect = 2e-68
Identities = 205/717 (28%), Positives = 288/717 (40%), Gaps = 142/717 (19%)
Query: 1594 NTEIGVGVSRSSC-CCSLG---KAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILE 1649
N G+ + + C CC LG +A G CE+ P + + + EG P + +
Sbjct: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
+ + + S E L D D DEC PG C
Sbjct: 567 PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD-----DQDECLLLPGELCQHLCI 621
Query: 1710 NTLGNYTCICPPEYMQVNGGHNCM--------DMRKSFCYRSYNGTTCENELPFNVTKRM 1761
NT+G+Y C C P + + G C + + +S N +P
Sbjct: 622 NTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL------ 675
Query: 1762 CCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICAN 1821
P P P T D CK+
Sbjct: 676 ----------------PLPQPNTCK---------------------DNGPCKQ------- 691
Query: 1822 GVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE---- 1877
VC GS C C G++ + CED DEC G + C R C+N+ GS+ C
Sbjct: 692 -VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTV 750
Query: 1878 -CAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCI----CHNGFKASQDQTM 1931
CA G+ L+ + CVD NEC+ + CS G CV+ GS+ C C G+ +
Sbjct: 751 LCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE-- 808
Query: 1932 CMDVDECER--HPCGNG-TCKNTVGSYNCL----CYPGFELTHNNDCLDIDECSSFFGQV 1984
C DVDEC H C G C+NT GS+ C C GF +C+DI+EC+S +
Sbjct: 809 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL-SEP 867
Query: 1985 CRNG-RCFNEIGSFKC-----LCNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEG 2037
CR G C N +GS+ C +C GY + DG C+D NEC C G C NL G
Sbjct: 868 CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPG 927
Query: 2038 SFRCICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRR 2095
S+RC C G++ + CID+NEC P +C NT G ++C C GF+L+ +G+R
Sbjct: 928 SYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 987
Query: 2096 CFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
C D + E +CS C+ + G ++Q C
Sbjct: 988 CEDVNEC------EAQRCSQE-----------CANIYG----------------SYQCYC 1014
Query: 2156 PYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECP-MGYNLDYTGVRCVDT 2214
G+ H T D++EC + GI +C+N GS++C CP GY + G C D
Sbjct: 1015 RQGYQLAEDGH-TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
Query: 2215 DECSIG-NPCGNG-TCTNVIGSFEC---NCNEGFEPGPMMNCE-----DINECAQNP 2261
DEC++G + C TC N+ GSF C C + CE D EC +P
Sbjct: 1074 DECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
Score = 253 bits (646), Expect = 2e-66
Identities = 180/552 (32%), Positives = 241/552 (43%), Gaps = 81/552 (14%)
Query: 2170 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2229
+D +ECL PG CINT GS+ C C G++L G C
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 2230 NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 2289
+ N P P C+D C Q C GS C+C GYA+ D
Sbjct: 663 SEFSQVASNTIPLPLPQPN-TCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADG 714
Query: 2290 KMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI-----CPPGMARRPDGEGCVDENECRT 2344
C+D DEC G HDC SR C N +G+F C+ C G + CVD NEC T
Sbjct: 715 VSCEDQDECLMGAHDC-SRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVT 772
Query: 2345 KPGICENG-RCVNIIGSYRC---------------------ECNEGFQSSSSGTECLDNR 2382
C G CVN +GS+ C EC G + G C N
Sbjct: 773 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLC-QNT 831
Query: 2383 QGLCFAEVLQTICQ--MASSSRNLVTKSEC------CCDG----GRGWGHQCELCPLPGT 2430
+G + + Q + N V +EC C G + C+ PL
Sbjct: 832 KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL--- 888
Query: 2431 AQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNGQ-CINTMGSFRCFCKVGYTTDISG 2486
IC G + DG D++EC+ + C GQ C N GS+RC CK G+ D G
Sbjct: 889 -----ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 943
Query: 2487 TSCIDLDECSQSP-KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF 2545
CID++EC SP + C + C+NT GSY+CSC G++L DGK C+D++EC+ ++ C
Sbjct: 944 RGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ 1001
Query: 2546 LCVNTLGGFTCKCPPGF--TQHHTACIDNNECGSQPS-LCGAKGICQNTPGSFSCEC-QR 2601
C N G + C C G+ + C D +EC LC + C N PGS+ C C ++
Sbjct: 1002 ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR--CLNVPGSYQCACPEQ 1059
Query: 2602 GFSLDATGLNCEDVDECD-GNHRCQHG--CQNILGGYRC---GCPQGYIQ----HYQWNQ 2651
G+++ A G +C+DVDEC G H C C NI G +RC CP Y+Q +
Sbjct: 1060 GYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTT 1119
Query: 2652 CVDENECSNPNA 2663
C D EC N A
Sbjct: 1120 CHDFLECQNSPA 1131
Score = 240 bits (612), Expect = 2e-62
Identities = 177/573 (30%), Positives = 250/573 (43%), Gaps = 99/573 (17%)
Query: 851 EDINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLICIDS--------------- 893
+D +EC P C N +GS++C C PG L G C
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 894 ------LKGTCWLNI-QDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLA 946
T L + Q + C+ N G + C+T+G + C P
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDN--GPC--KQVCSTVGGSAICSC--------FPGYAI 710
Query: 947 RIKGVTCEDVNECEVFPGVCPNGR-CVNSKGSFHCE-----CPEGLTLDGTGRVCLDIRM 1000
GV+CED +EC + C + CVN+ GSF+C C +G L+ R C+DI
Sbjct: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILN-AHRKCVDI-- 767
Query: 1001 EQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFAN 1060
+EC+ + R + C +G+ + C +PG + C
Sbjct: 768 ---------NECVTDLHTCSRGEHCVNTLGSFHCYKALTC-EPGYALKDGEC-------- 809
Query: 1061 RGDVLTGRPFYKDINECKAFPGMCTYG-KCRNTIGSFKC----RCNSGFALDMEERNCTD 1115
+D++EC C G C+NT GSF C RC GF D E NC D
Sbjct: 810 -----------EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD-PEGNCVD 857
Query: 1116 IDECRISPDLCGSGI-CVNTPGSFECE-----CFEGYESGFMMMKNCMDIDECERNPLLC 1169
I+EC + C G C+NT GS+ C+ C GY + K C+D++ECE C
Sbjct: 858 INECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTK-CVDVNECETGVHRC 916
Query: 1170 -RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCN 1228
G C N GS++CDC G + C+D+NEC S C N +G+Y+CSC
Sbjct: 917 GEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCA 976
Query: 1229 PGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECE 1288
G+ D + C D++EC C +C N GSY+C C +GY L DG +C DIDEC
Sbjct: 977 SGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECA 1034
Query: 1289 NNPDICDGGQCTNIPGEYRCLCYD-GFMASMDMKTCIDVNECDLNSNICMFGE-CENTKG 1346
I +C N+PG Y+C C + G+ + + ++C DV+EC L ++ C E C N +G
Sbjct: 1035 QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQG 1094
Query: 1347 SFIC---HCQLGY----SVKKGTTGCTDVDECE 1372
SF C C Y K T C D EC+
Sbjct: 1095 SFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
Score = 237 bits (604), Expect = 1e-61
Identities = 169/484 (34%), Positives = 224/484 (46%), Gaps = 62/484 (12%)
Query: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR-----QGLCFAEVLQ 2392
D++EC PG C+N +GSY C C GF G C + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 2393 TICQMASSSRNL-VTKSECCCDGGRGWGHQC-ELCPLPGTAQYKKICPHGPGYT--TDG- 2447
Q+AS++ L + + C D G C ++C G + IC PGY DG
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNG-----PCKQVCSTVGGSA---ICSCFPGYAIMADGV 715
Query: 2448 --RDIDECKVMPNLCTNGQ-CINTMGSFRC-----FCKVGYTTDISGTSCIDLDECSQSP 2499
D DEC + + C+ Q C+NT+GSF C C GY + + C+D++EC
Sbjct: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDL 774
Query: 2500 KPCNY--ICKNTEGSYQC----SCPRGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNTL 2551
C+ C NT GS+ C +C GY L+ DG+ C+D+DEC H CQ FLC NT
Sbjct: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQNTK 832
Query: 2552 GGFTC----KCPPGFTQHHTA-CIDNNECGSQPSLCGAKGICQNTPGSFSCE-----CQR 2601
G F C +C GF Q C+D NEC S C C NT GS++C+ C R
Sbjct: 833 GSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
Query: 2602 GFSLDATGLNCEDVDECD-GNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENEC 2658
G+ G C DV+EC+ G HRC G C N+ G YRC C G+ + C+D NEC
Sbjct: 893 GYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 952
Query: 2659 -SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGY 2717
++P +C NTLGSY+C+C SGF C DVNEC + + C+ C+N G Y
Sbjct: 953 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSY 1010
Query: 2718 LCGCPPGYYRVGQGH-------CVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGY 2770
C C GY GH C G G + L+ + A PE Y NG
Sbjct: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGI-LCTFRCLNVPGSYQCA-CPEQGYTMTANGR 1068
Query: 2771 SKKD 2774
S KD
Sbjct: 1069 SCKD 1072
Score = 236 bits (603), Expect = 2e-61
Identities = 195/668 (29%), Positives = 268/668 (40%), Gaps = 141/668 (21%)
Query: 1806 AVDIDECKEIP------GICANG---VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSN 1856
A+D DEC EIP +C C++ + C + ED D C
Sbjct: 453 AIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC-- 510
Query: 1857 GDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQ 1916
G +L ++ DC C G ++ G + N L P C+H + +G
Sbjct: 511 GISLYKQCCDC----------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEP 558
Query: 1917 CICHNGFKASQDQTMCMDVDECE---RHPCGNGT-------------------------- 1947
I + + V E E R GT
Sbjct: 559 LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH 618
Query: 1948 -CKNTVGSYNCLCYPGFELTHNN------------DCLDIDECSSFFGQV---------- 1984
C NTVGSY+C C+PGF L + + S F QV
Sbjct: 619 LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP 678
Query: 1985 ----CR-NGRCFNEI----GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT-CQN 2034
C+ NG C GS C C GY + DG +C D +EC+ CS C N
Sbjct: 679 QPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVN 738
Query: 2035 LEGSFRCI-----CPPGYEVKS-ENCIDINECDEDPNICLFGS-CTNTPGGFQC----LC 2083
GSF C+ C GY + + C+DINEC D + C G C NT G F C C
Sbjct: 739 TLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTC 798
Query: 2084 PPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELC 2143
PG+ L D C D +C++ +T + C G + C+
Sbjct: 799 EPGYALKDG--ECEDV-----------DECAM--GTHTCQPGFLCQNTKGSFY---CQAR 840
Query: 2144 PKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG-QCINTDGSFRCE----- 2197
+ + QD P G+ D+NEC C G CINT GS+ C+
Sbjct: 841 QRCMDGFLQD--PEGNCV---------DINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
Query: 2198 CPMGYNLDYTGVRCVDTDECSIG-NPCGNG-TCTNVIGSFECNCNEGFEPGPM-MNCEDI 2254
C GY+ G +CVD +EC G + CG G C N+ GS+ C+C GF+ C D+
Sbjct: 890 CARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV 949
Query: 2255 NECAQNP-LLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCK 2313
NEC +P LC C NT GSY C+C G+ L D K C+D++EC + + C
Sbjct: 950 NECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC-----EAQRCSQECA 1004
Query: 2314 NLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNE-GFQSS 2372
N+ G++ C C G DG C D +EC GI RC+N+ GSY+C C E G+ +
Sbjct: 1005 NIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1064
Query: 2373 SSGTECLD 2380
++G C D
Sbjct: 1065 ANGRSCKD 1072
Score = 231 bits (589), Expect = 8e-60
Identities = 214/776 (27%), Positives = 308/776 (39%), Gaps = 159/776 (20%)
Query: 593 NTDGSFQCICNAGFELTTDGKNCVDHDEC-TTTNMCLNGM---CINEDGSFKCICKPGFV 648
+T + C AG + D C++ E T N+C C++ C+ G +
Sbjct: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVL 494
Query: 649 LAPNGRYC--TDVDECQTPGICMNGHCINSEGSFRCDCPP-GLAVGMDGRVCVDTHMRST 705
A G C D D C GI + C CDC GL V +G+ C
Sbjct: 495 GAKEGETCGAEDNDSC---GISLYKQC--------CDCCGLGLRVRAEGQSCESNPNLGY 543
Query: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAK---NSAEFHGLCSSGVGI 762
+ C P V + P +P A + AE G + +G
Sbjct: 544 PCNHVMLSCCEGEEPLIVPEVR-----------RPPEPAAAPRRVSEAEMAGREALSLGT 592
Query: 763 TVD------GRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-------- 808
+ G D +EC L P +C N GSY C C G+ GR C
Sbjct: 593 EAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
Query: 809 ----------IDIDECLVNRL--------LC-DNG----LCRNTPGSYSCTCPPGYVFRT 845
+ + N + C DNG +C GS C+C PGY
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
Query: 846 ETETCEDINEC--ESNPCVNGA-CRNNLGSFNCE-----CSPGSKLSSTGLICIDSLKGT 897
+ +CED +EC ++ C C N LGSF C C+ G L++ C+D
Sbjct: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDI---- 767
Query: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVN 957
+ C +++ + C TLG+ C C G A +K CEDV+
Sbjct: 768 -------NECVTDLHTCSRGEHCVNTLGSF------HCYKALTCEPGYA-LKDGECEDVD 813
Query: 958 ECEVFPGVC-PNGRCVNSKGSFHCE----CPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
EC + C P C N+KGSF+C+ C +G D G C+DI +EC
Sbjct: 814 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDI-----------NEC 861
Query: 1013 I---HPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRP 1069
P F +C VG+ C+ P +C RG ++ G
Sbjct: 862 TSLSEPCRPGF---SCINTVGS---YTCQRNP--------LICARGYHASDDGTKCV--- 904
Query: 1070 FYKDINECKAFPGMCTYGK-CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS 1128
D+NEC+ C G+ C N GS++C C +GF D R C D++EC SP
Sbjct: 905 ---DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 961
Query: 1129 GICVNTPGSFECECFEGYESGFMMM---KNCMDIDECERNPLLCRGGTCVNTEGSFQCDC 1185
C NT GS+ C C SGF++ K C D++ECE C N GS+QC C
Sbjct: 962 HTCENTLGSYRCSC----ASGFLLAADGKRCEDVNECEAQRC---SQECANIYGSYQCYC 1014
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSC-NPGYQATPDRQGCTDID 1244
G++L+ C DI+EC+ + +C+N+ G+YQC+C GY T + + C D+D
Sbjct: 1015 RQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
Query: 1245 ECMIMNGGCD--TQCTNSEGSYEC---SCSEGYALMP----DGRSCADIDECENNP 1291
EC + C C N +GS+ C C Y + + +C D EC+N+P
Sbjct: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
Score = 203 bits (516), Expect = 2e-51
Identities = 153/467 (32%), Positives = 211/467 (45%), Gaps = 79/467 (16%)
Query: 471 VGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGR-CIPTVSSYRCE-----CNMG 524
VGG+ + + G I + + D C A+ C + C+ T+ S+ C C G
Sbjct: 696 VGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADG 755
Query: 525 YKQDANGDCIDVDECTSN--PCTNGD-CVNTPGSYYC----KCHAGFQRTPTKQACIDID 577
Y +A+ C+D++EC ++ C+ G+ CVNT GS++C C G+ + C D+D
Sbjct: 756 YILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD 813
Query: 578 ECIQNGVLCKNG-RCVNTDGSFQCI----CNAGFELTTDGKNCVDHDECTT-TNMCLNGM 631
EC C+ G C NT GSF C C GF +G NCVD +ECT+ + C G
Sbjct: 814 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
Query: 632 -CINEDGSFKC-----ICKPGFVLAPNGRYCTDVDECQTPGI--CMNGH-CINSEGSFRC 682
CIN GS+ C IC G+ + +G C DV+EC+T G+ C G C N GS+RC
Sbjct: 873 SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRC 931
Query: 683 DCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQ 742
DC G GR C+D + C A+P G CQ
Sbjct: 932 DCKAGFQRDAFGRGCIDVNE--------------------------CWASP----GRLCQ 961
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCNSGY 799
+ C+SG + DG+ D+NEC + C+ C N+ GSY+C C GY
Sbjct: 962 HTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQE-CANIYGSYQCYCRQGY 1018
Query: 800 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCP-PGYVFRTETETCEDINECE- 857
+ G C DIDEC + C N PGSY C CP GY +C+D++EC
Sbjct: 1019 QLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECAL 1078
Query: 858 -SNPCVNG-ACRNNLGSFNC---ECSPG----SKLSSTGLICIDSLK 895
++ C C N GSF C EC P SK C D L+
Sbjct: 1079 GTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLE 1125
Score = 201 bits (511), Expect = 9e-51
Identities = 167/556 (30%), Positives = 217/556 (39%), Gaps = 133/556 (23%)
Query: 496 DICKHHANLCLNGRCIPTVSSYRCECNMGYK-QDANGDC--------------------- 533
++C+H LC+N TV SY C C G+ QD C
Sbjct: 614 ELCQH---LCIN-----TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
Query: 534 ------------IDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQ 581
+ C N C GS C C G+ +C D DEC+
Sbjct: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLM 725
Query: 582 NGVLCKNGR-CVNTDGSFQCI-----CNAGFELTTDGKNCVDHDECTT-TNMCLNG-MCI 633
C + CVNT GSF C+ C G+ L K CVD +EC T + C G C+
Sbjct: 726 GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCV 784
Query: 634 NEDGSFKC----ICKPGFVLAPNGRYCTDVDEC-QTPGICMNGH-CINSEGSFRCD---- 683
N GSF C C+PG+ L C DVDEC C G C N++GSF C
Sbjct: 785 NTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 684 CPPGLAVGMDGRVCVD----THMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGE 739
C G +G CVD T + C G C+ S C NP
Sbjct: 843 CMDGFLQDPEGN-CVDINECTSLSEPCRPGFS---CIN-----TVGSYTCQRNP------ 887
Query: 740 PCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANG-ICENLRGSYRCNC 795
+C+ G + DG D+NEC C G +C NL GSYRC+C
Sbjct: 888 --------------LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 933
Query: 796 NSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINE 855
+G++ DA GR CID++EC + C NT GSY C+C G++ + + CED+NE
Sbjct: 934 KAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 993
Query: 856 CESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGAT 915
CE+ C + C N GS+ C C G +L+ G C D
Sbjct: 994 CEAQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDI---------------------- 1030
Query: 916 LKSECCATLGAAWGSPCERC--ELDTACPRG--LARIKGVTCEDVNECEVFPGVCPNGR- 970
EC G C ACP G +C+DV+EC + C
Sbjct: 1031 --DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAET 1088
Query: 971 CVNSKGSFHC---ECP 983
C N +GSF C ECP
Sbjct: 1089 CHNIQGSFRCLRFECP 1104
Score = 191 bits (485), Expect = 9e-48
Identities = 196/777 (25%), Positives = 289/777 (37%), Gaps = 154/777 (19%)
Query: 1176 NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK---CVNMIGTYQCSCNPGYQ 1232
+T+ + C G + + ++C++I E DN+CR + CV+ + C
Sbjct: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGA 496
Query: 1233 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPD 1292
+ G D D C I QC + C G + +G+SC E+NP+
Sbjct: 497 KEGETCGAEDNDSCGI---SLYKQCCDC-------CGLGLRVRAEGQSC------ESNPN 540
Query: 1293 I-----------CDGGQCTNIPGEYRC--------LCYDGFMASMDMKTC---------- 1323
+ C+G + +P R + MA + +
Sbjct: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 1324 --IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMH 1381
D +EC L C NT GS+ C C G+S++ C + H
Sbjct: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP-----------EGH 649
Query: 1382 ASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT 1441
P + + + L + + C GS C+C G+
Sbjct: 650 PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYA 709
Query: 1442 --GDGFTCSDVDECAENINLCENGQ-CLNVPGAYRCE-----CEMGFTPASDSRSCQDID 1493
DG +C D DEC + C Q C+N G++ C C G+ + R C DI+
Sbjct: 710 IMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYI-LNAHRKCVDIN 768
Query: 1494 ECSFQ-NICVFGT-CNNLPGMFHCI----CDDGYELDRTGGNCTDIDECADPIN-CVNG- 1545
EC + C G C N G FHC C+ GY L G C D+DECA + C G
Sbjct: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK--DGECEDVDECAMGTHTCQPGF 826
Query: 1546 LCVNTPGRYECN----CPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1601
LC NT G + C C F +P G CVD + C P G NT
Sbjct: 827 LCQNTKGSFYCQARQRCMDGFLQDPEG-NCVD--INECTSLSEPCRPGFSCINTVGSYTC 883
Query: 1602 SRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC 1661
R+ C+ G ++++ T C D++EC+ C
Sbjct: 884 QRNPLICARG------------YHASDDGTKCV---------------DVNECETGVHRC 916
Query: 1662 -QGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICP 1720
+G C N GS++C+C G+ R C D++EC+A PG TC NTLG+Y C C
Sbjct: 917 GEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCA 976
Query: 1721 PEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCP 1780
++ G C D+ + R C E C Y
Sbjct: 977 SGFLLAADGKRCEDVNECEAQR------CSQE---------CANIY-------------- 1007
Query: 1781 TPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECP-TGF 1839
++ C D HT DIDEC + GI C+N GS++C CP G+
Sbjct: 1008 ----GSYQCYCRQGYQLAEDGHT--CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1061
Query: 1840 SYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNEC 1896
+ C+D+DEC+ G + C C N GS+RC F+ PN V + +C
Sbjct: 1062 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC---LRFECPPNYVQVSKTKC 1115
Score = 187 bits (474), Expect = 2e-46
Identities = 158/532 (29%), Positives = 210/532 (39%), Gaps = 115/532 (21%)
Query: 2276 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI-------CPPGMA 2328
E C G D C ++ E + C + C C+ C G+
Sbjct: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC--------CVSYLQEKSCMAGVL 494
Query: 2329 RRPDGEGC--VDENECRTKPGICENGRCVNIIG--------SYRCECNE--GFQSSSSGT 2376
+GE C D + C GI +C + G CE N G+ +
Sbjct: 495 GAKEGETCGAEDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
Query: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
C + + L EV + A+ R V+++E G + EL
Sbjct: 551 SCCEGEEPLIVPEVRRPPEPAAAPRR--VSEAEMAGREALSLGTEAEL------------ 596
Query: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC-----ID 2491
P+ + G D DEC ++P CINT+GS+ C C G++ G +C
Sbjct: 597 -PN----SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPP 651
Query: 2492 LDECSQSPK---------------------------PCNYICKNTEGSYQCSCPRGYVLQ 2524
E Q P PC +C GS CSC GY +
Sbjct: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM 711
Query: 2525 EDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTC-----KCPPGFTQH-HTACIDNNECG 2576
DG +C+D DEC H+C + CVNTLG F C C G+ + H C+D NEC
Sbjct: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECV 771
Query: 2577 SQPSLCGAKGICQNTPGSFSC----ECQRGFSLDATGLNCEDVDECD-GNHRCQHG--CQ 2629
+ C C NT GSF C C+ G++L CEDVDEC G H CQ G CQ
Sbjct: 772 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQ 829
Query: 2630 NILGGYRC----GCPQGYIQHYQWNQCVDENEC---SNPNACGSASCYNTLGSYKC---- 2678
N G + C C G++Q + N CVD NEC S P G SC NT+GSY C
Sbjct: 830 NTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPG-FSCINTVGSYTCQRNP 887
Query: 2679 -ACPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYR 2727
C G+ + C DVNEC + + C G C N G Y C C G+ R
Sbjct: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 939
Score = 160 bits (404), Expect = 2e-38
Identities = 150/520 (28%), Positives = 198/520 (38%), Gaps = 109/520 (20%)
Query: 266 IPNIRTGACQDVDECQAIPG-ICQGGNCINTVGSFECRC--------------PAGH-KQ 309
+PN G D DEC +PG +CQ CINTVGS+ C C P GH Q
Sbjct: 596 LPNSLPG--DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
Query: 310 SETTQKCEDIDECSII-----------PGICETG-----ECSNTVGSYFCVCPRGYVTST 353
E Q+ E S + P C+ CS GS C C GY
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
Query: 354 DGSRCIDQ---------------------------RTGMCFSGLVNG--RCAQELPGRMT 384
DG C DQ T +C G + R ++ +T
Sbjct: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVT 772
Query: 385 KMQCC--------------------CEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMG 424
+ C CEPG G E V C G
Sbjct: 773 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECEDVDECAMGTHTCQPGFLCQ 829
Query: 425 GIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPI 484
GS + +GF GN + P GFS + G + P+
Sbjct: 830 NTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFS-CINTVGSYTCQRNPL 888
Query: 485 ITGLTIL-----NQTIDI--CKHHANLCLNGR-CIPTVSSYRCECNMGYKQDANG-DCID 535
I + +D+ C+ + C G+ C SYRC+C G+++DA G CID
Sbjct: 889 ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 948
Query: 536 VDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVN 593
V+EC ++P C NT GSY C C +GF + C D++EC C C N
Sbjct: 949 VNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECAN 1005
Query: 594 TDGSFQCICNAGFELTTDGKNCVDHDECTT-TNMCLNGMCINEDGSFKCIC-KPGFVLAP 651
GS+QC C G++L DG C D DEC + C+N GS++C C + G+ +
Sbjct: 1006 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTA 1065
Query: 652 NGRYCTDVDECQ--TPGICMNGHCINSEGSFRC---DCPP 686
NGR C DVDEC T C N +GSFRC +CPP
Sbjct: 1066 NGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1105
Score = 99.0 bits (245), Expect = 6e-20
Identities = 103/378 (27%), Positives = 147/378 (38%), Gaps = 55/378 (14%)
Query: 33 PPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNVCGSR 92
P P + P +QV S GS P Y A +A V Q + L G + C R
Sbjct: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGY----AIMADGVSCEDQDECLMGAHDCSRR 733
Query: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGF-------CSRPNMC-----TCSSGQ-ISS 139
+C + N ++ C DG+ C N C TCS G+ +
Sbjct: 734 --QFCVNTLGSFYCVNHTVL------CADGYILNAHRKCVDINECVTDLHTCSRGEHCVN 785
Query: 140 TCGSKSIQQCSVRCMNGGTCADDHCQ-CQKGYIGTYCGQP--VCENGCQNGGRCIGPNRC 196
T GS + ++ C G D C+ + +GT+ QP +C+N G R
Sbjct: 786 TLGSFHCYK-ALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQN---TKGSFYCQARQ 841
Query: 197 ACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPA 256
C+ GF C + ++ C+ G C T+ T C
Sbjct: 842 RCMDGFLQDPEGNCVDINECTSL--SEPCR---PGFSCINTVGSYT-----------CQR 885
Query: 257 QPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQK 315
P C RG+ + C DV+EC+ C +G C N GS+ C C AG ++ +
Sbjct: 886 NPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRG 945
Query: 316 CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRC 375
C D++EC PG C NT+GSY C C G++ + DG RC D C + RC
Sbjct: 946 CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCED--VNECEA----QRC 999
Query: 376 AQELPGRMTKMQCCCEPG 393
+QE QC C G
Sbjct: 1000 SQECANIYGSYQCYCRQG 1017
Score = 94.0 bits (232), Expect = 2e-18
Identities = 91/295 (30%), Positives = 116/295 (39%), Gaps = 60/295 (20%)
Query: 89 CGSRFHSYCCPGW--KTLPGGNQCIVPICRNSCGDGFCSRP-------NMCT-----CSS 134
C H+ C PG+ + G C R C DGF P N CT C
Sbjct: 815 CAMGTHT-CQPGFLCQNTKGSFYCQA---RQRCMDGFLQDPEGNCVDINECTSLSEPCRP 870
Query: 135 G-QISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG---CQNGGRC 190
G +T GS + Q+ + C G +DD +C CE G C G C
Sbjct: 871 GFSCINTVGSYTCQRNPLICARGYHASDDGTKC--------VDVNECETGVHRCGEGQVC 922
Query: 191 I---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
G RC C GF +RD C VN C A+ GR
Sbjct: 923 HNLPGSYRCDCKAGF-----QRDAFGRGCI-DVNE----------------CWASPGRLC 960
Query: 248 GHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H CE + C GF+ C+DV+EC+A C C N GS++C C G
Sbjct: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQG 1017
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP-RGYVTSTDGSRCID 360
++ +E C DIDEC+ GI T C N GSY C CP +GY + +G C D
Sbjct: 1018 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 276 bits (705), Expect = 3e-73
Identities = 147/413 (35%), Positives = 210/413 (50%), Gaps = 21/413 (5%)
Query: 1089 CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY-- 1146
C N GS+ CRC G+ L+ ++ C D C + C +CVN PGSF C+C+ GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1147 -ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECS 1205
E G K C+ +D C C CVN +GS+ C C G L+P ++ C I+ C+
Sbjct: 312 AEDG----KRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 1206 LSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYE 1265
S++ C++ +CVN +Y C C G+ PD++ C I+ C + GC+ +C N E SY
Sbjct: 367 SSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYY 425
Query: 1266 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1325
C C GY L P+G++C+ +D C C+ C N + C C +GF+ + D+KTC
Sbjct: 426 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSR 484
Query: 1326 VNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
V+ C L+ + C + C N SF C C G+ ++ C +D C +G H C+ SC+
Sbjct: 485 VDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE--HSCV 541
Query: 1386 NIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--T 1441
+ SF C C EG+I +G C D C H C CVN+ SY C C EGF
Sbjct: 542 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC--EHICVNSDDSYTCECLEGFRLA 599
Query: 1442 GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDE 1494
DG C D C + CE+ C+N +Y C+C GF A D R C+ E
Sbjct: 600 EDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 259 bits (662), Expect = 3e-68
Identities = 143/417 (34%), Positives = 205/417 (49%), Gaps = 16/417 (3%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 1190
C+N PGS+ C C +GY C D C C CVN GSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILN-SDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYA 310
Query: 1191 LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 1250
L+ + CV ++ C+ ++ C + +CVN G+Y C C+ G+ PD++ CT ID C N
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN 369
Query: 1251 GGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLC 1310
GC +C N++ SY C C +G+ L PD ++C I+ C N C+ +C N+ Y C C
Sbjct: 370 HGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE-HECVNMEESYYCRC 428
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDE 1370
+ G+ + KTC V+ C + C C NT+ SF+C C G+ + + C+ VD
Sbjct: 429 HRGYTLDPNGKTCSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 1371 CEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNT 1428
C + H C+ SC+N+ SF C C EG + +G C LD C+ G H C CV++
Sbjct: 488 CLLSDHGCEY--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC--EHSCVSS 543
Query: 1429 PGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDS 1486
S+ C C EG+ DG TC D C + CE+ C+N +Y CEC GF A D
Sbjct: 544 EDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDG 602
Query: 1487 RSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCV 1543
+ C+ D C + C N + C C +G+ L G C E PI+ V
Sbjct: 603 KRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE--GPIDLV 657
Score = 253 bits (645), Expect = 3e-66
Identities = 142/422 (33%), Positives = 199/422 (47%), Gaps = 12/422 (2%)
Query: 1174 CVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQA 1233
C+N GS+ C C G+ L+ + C + C++ D+ C CVN+ G++ C C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1234 TPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDI 1293
D + C +D C N GC+ +C N++GSY C C EG+AL PD ++C ID C ++
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1294 CDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQ 1353
C +C N Y C C GF + D KTC +N C LN C EC N + S+ C C
Sbjct: 372 CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 429
Query: 1354 LGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN-GIK-CIDLDE 1411
GY++ C+ VD C H C+ CLN SF C C EG++ N +K C +D
Sbjct: 430 RGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 1412 CSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVP 1469
C H C + CVN S+ C C EG DG TC+ +D CA + CE+ C++
Sbjct: 488 CLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSE 544
Query: 1470 GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGN 1529
++ C+C G+ D ++C+ D C + C N + C C +G+ L G
Sbjct: 545 DSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 1589
C D C + +CVN Y C C F L G C G L F G
Sbjct: 605 CRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSK 664
Query: 1590 SL 1591
SL
Sbjct: 665 SL 666
Score = 234 bits (598), Expect = 7e-61
Identities = 139/443 (31%), Positives = 191/443 (43%), Gaps = 48/443 (10%)
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2323
CA C+N GSY C C GY L DQ C+ D CA H+CE +C N+ G+F+C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ---LCVNVPGSFVCQC 305
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2383
G A DG+ CV + C ++ CE+ CVN GSY C+C+EGF + C
Sbjct: 306 YSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC----- 359
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 2443
TK + C G H+C + Y C G
Sbjct: 360 ----------------------TKIDYCASSNHGCQHEC----VNTDDSYSCHCLKGFTL 393
Query: 2444 TTDG---RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPK 2500
D R I+ C + C + +C+N S+ C C GYT D +G +C +D C+Q
Sbjct: 394 NPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDH 452
Query: 2501 PCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPP 2560
C +C NTE S+ C C G+++ ED KTC +D C H C++ CVN F C+CP
Sbjct: 453 GCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPE 512
Query: 2561 GFTQHHTACIDNNECGSQPSLC----GAKGICQNTPGSFSCECQRGFSLDATGLNCEDVD 2616
G H D C S G + C ++ SF C+C G+ L G C D
Sbjct: 513 G----HVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 2617 ECDG-NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGS 2675
C +H C+H C N Y C C +G+ +C ++ C + + C N S
Sbjct: 569 VCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNS 628
Query: 2676 YKCACPSGFSFDQFSSACHDVNE 2698
Y C C GF + C E
Sbjct: 629 YICKCSEGFVLAEDGRRCKKCTE 651
Score = 211 bits (538), Expect = 6e-54
Identities = 135/460 (29%), Positives = 197/460 (42%), Gaps = 60/460 (13%)
Query: 1246 CMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGE 1305
C + C C N GSY C C +GY L D +C D C C+ C N+PG
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPGS 300
Query: 1306 YRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC 1365
+ C CY G+ + D K C+ V+ C ++ C EC N GS++C C G+++ C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 1366 TDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINA 1423
T +D C H C C+N S+ C C +G+ N K C ++ C+ C
Sbjct: 360 TKIDYCASSNHGC--QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC--EH 415
Query: 1424 QCVNTPGSYRCACSEGFTGD--GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 1481
+CVN SY C C G+T D G TCS VD CA+ + CE CLN ++ C+C GF
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFL 474
Query: 1482 PASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN 1541
D ++C +D C + +C N+ F C C +G+ L G C +D CA +
Sbjct: 475 INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDH 534
Query: 1542 CVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1601
CV++ + C C + L G C
Sbjct: 535 GCEHSCVSSEDSFVCQCFEGYILREDGKTC------------------------------ 564
Query: 1602 SRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC 1661
R C ++ + C VNS + YT C EGFR + ED C+ +C
Sbjct: 565 RRKDVCQAIDHGCEHIC-----VNSDDSYT-CECLEGFR------LAEDGKRCRR-KDVC 611
Query: 1662 QGGN------CINTFGSFQCECPQGYYLSEDTRICEDIDE 1695
+ + C+N S+ C+C +G+ L+ED R C+ E
Sbjct: 612 KSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 207 bits (528), Expect = 9e-53
Identities = 119/380 (31%), Positives = 167/380 (43%), Gaps = 40/380 (10%)
Query: 2187 CINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPG 2246
C+N GSF C+C GY L G RCV D C+ N C N GS+ C C+EGF
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALN 353
Query: 2247 P-MMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
P C I+ CA + C C+NT SY C C G+ L D+K C+ ++ CA C
Sbjct: 354 PDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC 413
Query: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2365
E C N+ ++ C C G P+G+ C + C + CE C+N S+ C+C
Sbjct: 414 EHE---CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQC 469
Query: 2366 NEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELC 2425
+EGF + C +R C H CE
Sbjct: 470 SEGFLINEDLKTC--SRVDYCLLS-----------------------------DHGCEYS 498
Query: 2426 PLPGTAQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTT 2482
+ + CP G +DG+ +D C + + C + C+++ SF C C GY
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYIL 557
Query: 2483 DISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN 2542
G +C D C C +IC N++ SY C C G+ L EDGK C+ D C++ H
Sbjct: 558 REDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG 617
Query: 2543 CQFLCVNTLGGFTCKCPPGF 2562
C+ +CVN + CKC GF
Sbjct: 618 CEHICVNNGNSYICKCSEGF 637
Score = 207 bits (527), Expect = 1e-52
Identities = 138/452 (30%), Positives = 205/452 (45%), Gaps = 55/452 (12%)
Query: 1341 CENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 1400
C N GS++C C+ GY + T C D C + HNC+ C+N+PGSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 1401 --GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAEN 1456
+G +C+ +D C++ H C +CVN GSY C C EGF D TC+ +D CA +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCE--HECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASS 368
Query: 1457 INLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCI 1516
+ C++ +C+N +Y C C GFT D ++C+ I+ C+ C N+ ++C
Sbjct: 369 NHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCR 427
Query: 1517 CDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRV 1576
C GY LD G C+ +D CA + LC+NT + C C F +N C +RV
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC--SRV 485
Query: 1577 GNCYLKFGPRGDGSLSCNTEIGVGVSRS-SCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
C L SC V + RS +C C G + +TC ++S C
Sbjct: 486 DYCLLS---DHGCEYSC-----VNMDRSFACQCPEGHVLRSDGKTCAKLDS------CAL 531
Query: 1636 GEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDE 1695
G+ C+ +C+++ SF C+C +GY L ED + C D
Sbjct: 532 GD--------------HGCEH--------SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 1696 CFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF 1755
C A C C N+ +YTC C + G C RK C +++G CE+
Sbjct: 570 CQAIDHGC-EHICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVCKSTHHG--CEHICVN 624
Query: 1756 NVTKRMCCCTYNVGKAWN-KPCEPCPTPGTAD 1786
N +C C+ A + + C+ C T G D
Sbjct: 625 NGNSYICKCSEGFVLAEDGRRCKKC-TEGPID 655
Score = 207 bits (527), Expect = 1e-52
Identities = 127/450 (28%), Positives = 203/450 (45%), Gaps = 55/450 (12%)
Query: 971 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD---EDECIHPVPGKFRMDACCC 1027
C+N GS+ C C +G L+ C R++ D E C++ VPG F C C
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTC---RIQDLCAMEDHNCEQLCVN-VPGSF---VCQC 305
Query: 1028 AVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG 1087
G A + + C ++ C + C +
Sbjct: 306 YSGYALAEDGKRCVA-------------------------------VDYCASENHGCEH- 333
Query: 1088 KCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE 1147
+C N GS+ C+C+ GFAL+ +++ CT ID C S C CVNT S+ C C +G+
Sbjct: 334 ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC-QHECVNTDDSYSCHCLKGFT 392
Query: 1148 SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLS 1207
K C I+ C N C CVN E S+ C C G+ L P+ + C ++ C+
Sbjct: 393 LN-PDKKTCRRINYCALNKPGCE-HECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQ 450
Query: 1208 DNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1267
D+ C C+N ++ C C+ G+ D + C+ +D C++ + GC+ C N + S+ C
Sbjct: 451 DHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ 509
Query: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
C EG+ L DG++CA +D C C+ C + + C C++G++ D KTC +
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 1328 ECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNI 1387
C + C C N+ S+ C C G+ + + C D C+ H C+ C+N
Sbjct: 569 VCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE--HICVNN 625
Query: 1388 PGSFKCSCREGWI--GNGIKCIDLDECSNG 1415
S+ C C EG++ +G +C +C+ G
Sbjct: 626 GNSYICKCSEGFVLAEDGRRC---KKCTEG 652
Score = 206 bits (524), Expect = 3e-52
Identities = 123/443 (27%), Positives = 184/443 (41%), Gaps = 50/443 (11%)
Query: 2298 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2357
C+ H+C C N+ G+++C C G D C ++ C + CE CVN+
Sbjct: 242 CSTLEHNCAH---FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNV 297
Query: 2358 IGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRG 2417
GS+ C+C G+ + G C+ + C G
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCV---------------------------AVDYCASENHG 330
Query: 2418 WGHQCELCPLPGTAQYKKICPHGPGYTTDGRD---IDECKVMPNLCTNGQCINTMGSFRC 2474
H+C + Y C G D + ID C + C + +C+NT S+ C
Sbjct: 331 CEHEC----VNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSC 385
Query: 2475 FCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLD 2534
C G+T + +C ++ C+ + C + C N E SY C C RGY L +GKTC +D
Sbjct: 386 HCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVD 445
Query: 2535 ECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLC-----GAKGICQ 2589
C + H C+ LC+NT F C+C GF + D C S+ C G + C
Sbjct: 446 HCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE----DLKTC-SRVDYCLLSDHGCEYSCV 500
Query: 2590 NTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
N SF+C+C G L + G C +D C G+H C+H C + + C C +GYI
Sbjct: 501 NMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Query: 2649 WNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNY 2708
C ++ C + C N+ SY C C GF + C + C S+ + C +
Sbjct: 561 GKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH 620
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQG 2731
C N Y+C C G+ G
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDG 643
Score = 190 bits (482), Expect = 2e-47
Identities = 140/458 (30%), Positives = 204/458 (44%), Gaps = 57/458 (12%)
Query: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKL-SPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
CS ++ C CIN PGSY C C G+ L S C ++ C + C LCV++
Sbjct: 242 CSTLEHNCAHF--CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVP 298
Query: 1913 GSYQCICHNGFKASQDQTMCMDVDEC--ERHPCGNGTCKNTVGSYNCLCYPGFELT-HNN 1969
GS+ C C++G+ ++D C+ VD C E H C + C N GSY C C+ GF L
Sbjct: 299 GSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKK 357
Query: 1970 DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP 2029
C ID C+S C++ C N S+ C C +G+ L PD K C N C C
Sbjct: 358 TCTKIDYCAS-SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE- 414
Query: 2030 GTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 2087
C N+E S+ C C GY + + C ++ C + + C C NT F C C GF
Sbjct: 415 HECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGF 473
Query: 2088 VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDD 2147
+++++ + C +R +C + ++G CE +
Sbjct: 474 LINEDLKTC--SRVDYCLLS-DHG----------------------------CEYSCVNM 502
Query: 2148 EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYT 2207
+ +F CP GH + S T ++ C C + C++++ SF C+C GY L
Sbjct: 503 DRSFACQCPEGH-VLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILRED 560
Query: 2208 GVRCVDTDEC-SIGNPCGNGTCTNVIGSFECNCNEGF---EPGPMMNCEDINECAQNPLL 2263
G C D C +I + C + C N S+ C C EGF E G +D+ C
Sbjct: 561 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDV--CKSTHHG 617
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEG 2301
C C+N SY C C G+ L ED + CK +C EG
Sbjct: 618 CEHICVNNGNSYICKCSEGFVLAEDGRRCK---KCTEG 652
Score = 188 bits (478), Expect = 6e-47
Identities = 133/434 (30%), Positives = 186/434 (42%), Gaps = 37/434 (8%)
Query: 467 FSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYK 526
F + G+ V QG I+ + D+C + C C+ S+ C+C GY
Sbjct: 252 FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPGSFVCQCYSGYA 310
Query: 527 QDANGD-CIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGV 584
+G C+ VD C S N +CVN GSY C+CH GF P K+ C ID C +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNH 370
Query: 585 LCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICK 644
C++ CVNTD S+ C C GF L D K C + C C+N + S+ C C
Sbjct: 371 GCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCH 429
Query: 645 PGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
G+ L PNG+ C+ VD C C+N+E SF C C G + D + C
Sbjct: 430 RGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS------ 483
Query: 705 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 764
+ C+ G E C N D F CQ CP E H L S G
Sbjct: 484 ------RVDYCLLSDHGC----EYSCVNMDRSFA--CQ-CP-----EGHVLRSDGKTCA- 524
Query: 765 DGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG 824
++ CAL C + C + S+ C C GY G+ C D C C++
Sbjct: 525 ---KLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH- 579
Query: 825 LCRNTPGSYSCTCPPGYVFRTETETCEDINECES--NPCVNGACRNNLGSFNCECSPGSK 882
+C N+ SY+C C G+ + + C + C+S + C + C NN S+ C+CS G
Sbjct: 580 ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFV 638
Query: 883 LSSTGLICIDSLKG 896
L+ G C +G
Sbjct: 639 LAEDGRRCKKCTEG 652
Score = 182 bits (462), Expect = 4e-45
Identities = 127/468 (27%), Positives = 191/468 (40%), Gaps = 69/468 (14%)
Query: 539 CTSNPCTNGD------CVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCV 592
CT++ C+ + C+N PGSY C+C G+ + C D C C+ CV
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCV 295
Query: 593 NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPN 652
N GSF C C +G+ L DGK CV D C + N C+N DGS+ C C GF L P+
Sbjct: 296 NVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 653 GRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKK 712
+ CT +D C + C+N++ S+ C C G + D + C R Y + K
Sbjct: 356 KKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC-----RRINYCALNK 410
Query: 713 GVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRD---I 769
C E C N + ++ C G + +G+ +
Sbjct: 411 PGC-----------EHECVNME---------------ESYYCRCHRGYTLDPNGKTCSRV 444
Query: 770 NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT 829
+ CA C +C N S+ C C+ G+ + + C +D CL++ C+ C N
Sbjct: 445 DHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS-CVNM 502
Query: 830 PGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGACRNNLGSFNCECSPGSKLSSTG 887
S++C CP G+V R++ +TC ++ C + C + +C ++ SF C+C G L G
Sbjct: 503 DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDG 561
Query: 888 LICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLAR 947
C K C D CE + C G +RC C +
Sbjct: 562 KTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC-----K 612
Query: 948 IKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
CE + CVN+ S+ C+C EG L GR C
Sbjct: 613 STHHGCEHI--------------CVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 182 bits (462), Expect = 4e-45
Identities = 122/401 (30%), Positives = 172/401 (42%), Gaps = 46/401 (11%)
Query: 1990 CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEV 2049
C N GS+ C C +GY L D C + C +C C N+ GSF C C GY +
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 2050 KSEN--CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTN 2107
+ C+ ++ C + + C C N G + C C GF L+ + + C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC----------- 359
Query: 2108 FENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHD 2167
TK C S G C+ + + ++ C G P
Sbjct: 360 --------------TKIDYCASSNHG------CQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 2168 TREDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG 2226
R +N C L PG C + +C+N + S+ C C GY LD G C D C+ +
Sbjct: 400 CRR-INYCALNKPG-CEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 2227 TCTNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYAL 2285
C N SF C C+EGF + C ++ C + C + C+N S+ C CP G+ L
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVL 516
Query: 2286 REDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK 2345
R D K C LD CA G H CE C + +F+C C G R DG+ C ++ C+
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEH---SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI 573
Query: 2346 PGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 2386
CE+ CVN SY CEC EGF+ + G C R+ +C
Sbjct: 574 DHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVC 611
Score = 182 bits (461), Expect = 5e-45
Identities = 101/322 (31%), Positives = 145/322 (45%), Gaps = 12/322 (3%)
Query: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGS 2512
C + + C + CIN GS+ C CK GY + T+C D C+ C +C N GS
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300
Query: 2513 YQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH--HTACI 2570
+ C C GY L EDGK C +D C ++ H C+ CVN G + C+C GF + C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQ 2629
+ C S S G + C NT S+SC C +GF+L+ C ++ C N C+H C
Sbjct: 361 KIDYCAS--SNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECV 418
Query: 2630 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQF 2689
N+ Y C C +GY C + C+ + C NT S+ C C GF ++
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINED 478
Query: 2690 SSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDT 2749
C V+ C S + C Y C N + + C CP G+ G + K +L
Sbjct: 479 LKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA-----KLDSCALGD 533
Query: 2750 EVDEENALSPEACYECK-INGY 2770
E + +S E + C+ GY
Sbjct: 534 HGCEHSCVSSEDSFVCQCFEGY 555
Score = 181 bits (459), Expect = 9e-45
Identities = 128/447 (28%), Positives = 186/447 (41%), Gaps = 44/447 (9%)
Query: 1941 HPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
H C + C N GSY C C G+ L + I + + C C N GSF C
Sbjct: 247 HNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQ 304
Query: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
C GY L DGK C+ + C + C C N +GS+ C C G+ + + C I+
Sbjct: 305 CYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKID 363
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2118
C + C C NT + C C GF L+ + + C R ++C N
Sbjct: 364 YCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYCALN----------- 409
Query: 2119 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2178
PG CE + E ++ C G+ P+ T V+ C +
Sbjct: 410 ------------KPG------CEHECVNMEESYYCRCHRGYTLDPN-GKTCSRVDHCAQQ 450
Query: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECN 2238
C C+NT+ SF C+C G+ ++ C D C + + +C N+ SF C
Sbjct: 451 DHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ 509
Query: 2239 CNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDE 2297
C EG C ++ CA C C+++ S+ C C GY LRED K C+ D
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 2298 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2357
C H CE +C N ++ C C G DG+ C ++ C++ CE+ CVN
Sbjct: 570 CQAIDHGCEH---ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNN 625
Query: 2358 IGSYRCECNEGFQSSSSGTECLDNRQG 2384
SY C+C+EGF + G C +G
Sbjct: 626 GNSYICKCSEGFVLAEDGRRCKKCTEG 652
Score = 157 bits (396), Expect = 2e-37
Identities = 114/440 (25%), Positives = 170/440 (38%), Gaps = 65/440 (14%)
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELD 1524
C+N+PG+Y C C+ G+ SD +C+ D C+ ++ C N+PG F C C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1525 RTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFG 1584
G C +D CA + CVN G Y C C F LNP C ++ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC--TKIDYC----- 365
Query: 1585 PRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN----------------STE 1628
+ C E SC C G +TC +N
Sbjct: 366 --ASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEES 423
Query: 1629 YYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTR 1688
YY C G PN T +D C + C+ C+NT SF C+C +G+ ++ED +
Sbjct: 424 YYCRCHRGYTLDPNGKT--CSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLK 480
Query: 1689 ICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTT 1748
C +D C C +C N ++ C CP ++ + G C + C +G
Sbjct: 481 TCSRVDYCLLSDHGC-EYSCVNMDRSFACQCPEGHVLRSDGKTCAKL--DSCALGDHG-- 535
Query: 1749 CENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD 1808
CE+ + +C C G+
Sbjct: 536 CEHSCVSSEDSFVCQC-----------------------------FEGYILREDGKTCRR 566
Query: 1809 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
D C+ I C + +C+N S+ CEC GF + C D C + + C+ C+
Sbjct: 567 KDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH--ICV 623
Query: 1869 NSPGSYRCECAAGFKLSPNG 1888
N+ SY C+C+ GF L+ +G
Sbjct: 624 NNGNSYICKCSEGFVLAEDG 643
Score = 155 bits (392), Expect = 6e-37
Identities = 127/466 (27%), Positives = 176/466 (37%), Gaps = 79/466 (16%)
Query: 1506 CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLN 1565
C N+PG + C C GY L+ C D CA + LCVN PG + C C + L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
G CV C S + C VN
Sbjct: 313 EDGKRCV------------------------------AVDYCASENHGCEHEC-----VN 337
Query: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
+ Y LC EGF NP ID C CQ C+NT S+ C C +G+ L+
Sbjct: 338 ADGSY-LCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNP 395
Query: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
D + C I+ C + C C N +Y C C Y G C R C + +
Sbjct: 396 DKKTCRRINYCALNKPGC-EHECVNMEESYYCRCHRGYTLDPNGKTCS--RVDHCAQQDH 452
Query: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1805
G CE ++C T + +C GF +
Sbjct: 453 G--CE---------QLCLNTED--------------------SFVCQCSEGFLINEDLKT 481
Query: 1806 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA 1865
+D C C C+N SF C+CP G C +D C+ GD+ C+ +
Sbjct: 482 CSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS- 539
Query: 1866 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
C++S S+ C+C G+ L +G C ++ C I + C H +CV+ SY C C GF+
Sbjct: 540 -CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFR 597
Query: 1925 ASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELTHN 1968
++D C D C+ H C + C N SY C C GF L +
Sbjct: 598 LAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAED 642
Score = 151 bits (382), Expect = 8e-36
Identities = 127/478 (26%), Positives = 184/478 (38%), Gaps = 86/478 (17%)
Query: 779 CANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCP 838
CA+ C N+ GSY C C GY ++ C D C + C+ LC N PGS+ C C
Sbjct: 249 CAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 306
Query: 839 PGYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT 897
GY + + C ++ C S N C N GS+ C+C G L+ K T
Sbjct: 307 SGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD--------KKT 358
Query: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVT----- 952
C K + CA+ C + +C +KG T
Sbjct: 359 C-----------------TKIDYCASSNHGCQHECVNTDDSYSCHC----LKGFTLNPDK 397
Query: 953 --CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDED 1010
C +N C + C + CVN + S++C C G TLD G+ C + D
Sbjct: 398 KTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRV-----------D 445
Query: 1011 ECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPF 1070
C G + C ++ +C E GF D+ T
Sbjct: 446 HCAQQDHG---CEQLCLNTEDSFVCQCSE-----------------GFLINEDLKT---- 481
Query: 1071 YKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 1130
++ C C Y C N SF C+C G L + + C +D C + C
Sbjct: 482 CSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS- 539
Query: 1131 CVNTPGSFECECFEGY---ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPL 1187
CV++ SF C+CFEGY E G K C D C+ C CVN++ S+ C+C
Sbjct: 540 CVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAIDHGCE-HICVNSDDSYTCECLE 594
Query: 1188 GHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDE 1245
G L+ + C + C + + C + CVN +Y C C+ G+ D + C E
Sbjct: 595 GFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 138 bits (348), Expect = 7e-32
Identities = 88/298 (29%), Positives = 124/298 (41%), Gaps = 22/298 (7%)
Query: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSN-PCTNGDCVNT 552
ID C + C + C+ T SY C C G+ + + C ++ C N P +CVN
Sbjct: 362 IDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNM 420
Query: 553 PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDG 612
SYYC+CH G+ P + C +D C Q C+ C+NT+ SF C C+ GF + D
Sbjct: 421 EESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDL 479
Query: 613 KNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGH 672
K C D C ++ C+N D SF C C G VL +G+ C +D C
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS 539
Query: 673 CINSEGSFRCDCPPGLAVGMDGRVC--------VDTHMRSTCYGGIKKGVC--VRPFPGA 722
C++SE SF C C G + DG+ C +D C C + F A
Sbjct: 540 CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA 599
Query: 723 VTKSEC----CCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDP 776
C C + +G C+ N + CS G + DGR +C P
Sbjct: 600 EDGKRCRRKDVCKSTHHG----CEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 79.3 bits (194), Expect = 5e-14
Identities = 77/311 (24%), Positives = 111/311 (35%), Gaps = 67/311 (21%)
Query: 87 NVCGSRFHSYCCPGWKTLPGGNQCI-VPICRNS------------------CGDGFCSRP 127
NV GS F C G+ G +C+ V C + C +GF P
Sbjct: 296 NVPGS-FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNP 354
Query: 128 NMCTCSSGQISSTCGSKSIQQC-------SVRCMNGGTCADDHCQCQKGYIGTYCG--QP 178
+ TC+ ++ +C S C+ G T D C++ YC +P
Sbjct: 355 DKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRI---NYCALNKP 411
Query: 179 VCENGCQNGGRCIGPNRCACVYGFT-GPQCERDYRTGPCFTQVNN--QMCQGQLTGIVCT 235
CE+ C N C C G+T P + R C Q + Q+C VC
Sbjct: 412 GCEHECVNMEESY---YCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQ 468
Query: 236 KTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINT 295
C GF+ N C VD C C+ +C+N
Sbjct: 469 -------------------------CSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVNM 502
Query: 296 VGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDG 355
SF C+CP GH + C +D C++ CE C ++ S+ C C GY+ DG
Sbjct: 503 DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDG 561
Query: 356 SRCIDQRTGMC 366
C +R +C
Sbjct: 562 KTC--RRKDVC 570
Score = 70.1 bits (170), Expect = 3e-11
Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 11/166 (6%)
Query: 233 VCTKTLC----CATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGIC 287
V K LC C+T+ H C P C++G+I N C+ D C C
Sbjct: 231 VFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC 290
Query: 288 QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPR 347
+ C+N GSF C+C +G+ +E ++C +D C+ CE EC N GSY C C
Sbjct: 291 EQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHE 348
Query: 348 GYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
G+ + D C T + + N C E C C G
Sbjct: 349 GFALNPDKKTC----TKIDYCASSNHGCQHECVNTDDSYSCHCLKG 390
Score = 67.8 bits (164), Expect = 2e-10
Identities = 69/257 (26%), Positives = 88/257 (34%), Gaps = 49/257 (19%)
Query: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGT- 173
CR C G+ PN TCS C + C C+N T CQC +G++
Sbjct: 426 CR--CHRGYTLDPNGKTCSR---VDHCAQQD-HGCEQLCLN--TEDSFVCQCSEGFLINE 477
Query: 174 ---------YC--GQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNN 222
YC CE C N R C C G
Sbjct: 478 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFA---CQCPEGHVL------------------ 516
Query: 223 QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQ-PQPCRRGFIPNIRTGACQDVDECQ 281
+ G C K CA H C C G+I C+ D CQ
Sbjct: 517 -----RSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQ 571
Query: 282 AIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSY 341
AI C+ C+N+ S+ C C G + +E ++C D C CE C N SY
Sbjct: 572 AIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSY 629
Query: 342 FCVCPRGYVTSTDGSRC 358
C C G+V + DG RC
Sbjct: 630 ICKCSEGFVLAEDGRRC 646
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 276 bits (705), Expect = 3e-73
Identities = 147/413 (35%), Positives = 210/413 (50%), Gaps = 21/413 (5%)
Query: 1089 CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY-- 1146
C N GS+ CRC G+ L+ ++ C D C + C +CVN PGSF C+C+ GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1147 -ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECS 1205
E G K C+ +D C C CVN +GS+ C C G L+P ++ C I+ C+
Sbjct: 312 AEDG----KRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 1206 LSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYE 1265
S++ C++ +CVN +Y C C G+ PD++ C I+ C + GC+ +C N E SY
Sbjct: 367 SSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYY 425
Query: 1266 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1325
C C GY L P+G++C+ +D C C+ C N + C C +GF+ + D+KTC
Sbjct: 426 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSR 484
Query: 1326 VNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
V+ C L+ + C + C N SF C C G+ ++ C +D C +G H C+ SC+
Sbjct: 485 VDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE--HSCV 541
Query: 1386 NIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--T 1441
+ SF C C EG+I +G C D C H C CVN+ SY C C EGF
Sbjct: 542 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC--EHICVNSDDSYTCECLEGFRLA 599
Query: 1442 GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDE 1494
DG C D C + CE+ C+N +Y C+C GF A D R C+ E
Sbjct: 600 EDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 259 bits (662), Expect = 3e-68
Identities = 143/417 (34%), Positives = 205/417 (49%), Gaps = 16/417 (3%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 1190
C+N PGS+ C C +GY C D C C CVN GSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILN-SDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYA 310
Query: 1191 LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 1250
L+ + CV ++ C+ ++ C + +CVN G+Y C C+ G+ PD++ CT ID C N
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN 369
Query: 1251 GGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLC 1310
GC +C N++ SY C C +G+ L PD ++C I+ C N C+ +C N+ Y C C
Sbjct: 370 HGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE-HECVNMEESYYCRC 428
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDE 1370
+ G+ + KTC V+ C + C C NT+ SF+C C G+ + + C+ VD
Sbjct: 429 HRGYTLDPNGKTCSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 1371 CEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNT 1428
C + H C+ SC+N+ SF C C EG + +G C LD C+ G H C CV++
Sbjct: 488 CLLSDHGCEY--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC--EHSCVSS 543
Query: 1429 PGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDS 1486
S+ C C EG+ DG TC D C + CE+ C+N +Y CEC GF A D
Sbjct: 544 EDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDG 602
Query: 1487 RSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCV 1543
+ C+ D C + C N + C C +G+ L G C E PI+ V
Sbjct: 603 KRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE--GPIDLV 657
Score = 253 bits (645), Expect = 3e-66
Identities = 142/422 (33%), Positives = 199/422 (47%), Gaps = 12/422 (2%)
Query: 1174 CVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQA 1233
C+N GS+ C C G+ L+ + C + C++ D+ C CVN+ G++ C C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1234 TPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDI 1293
D + C +D C N GC+ +C N++GSY C C EG+AL PD ++C ID C ++
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1294 CDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQ 1353
C +C N Y C C GF + D KTC +N C LN C EC N + S+ C C
Sbjct: 372 CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCH 429
Query: 1354 LGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN-GIK-CIDLDE 1411
GY++ C+ VD C H C+ CLN SF C C EG++ N +K C +D
Sbjct: 430 RGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 1412 CSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVP 1469
C H C + CVN S+ C C EG DG TC+ +D CA + CE+ C++
Sbjct: 488 CLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSE 544
Query: 1470 GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGN 1529
++ C+C G+ D ++C+ D C + C N + C C +G+ L G
Sbjct: 545 DSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 1589
C D C + +CVN Y C C F L G C G L F G
Sbjct: 605 CRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSK 664
Query: 1590 SL 1591
SL
Sbjct: 665 SL 666
Score = 234 bits (598), Expect = 7e-61
Identities = 139/443 (31%), Positives = 191/443 (43%), Gaps = 48/443 (10%)
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2323
CA C+N GSY C C GY L DQ C+ D CA H+CE +C N+ G+F+C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ---LCVNVPGSFVCQC 305
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2383
G A DG+ CV + C ++ CE+ CVN GSY C+C+EGF + C
Sbjct: 306 YSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC----- 359
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 2443
TK + C G H+C + Y C G
Sbjct: 360 ----------------------TKIDYCASSNHGCQHEC----VNTDDSYSCHCLKGFTL 393
Query: 2444 TTDG---RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPK 2500
D R I+ C + C + +C+N S+ C C GYT D +G +C +D C+Q
Sbjct: 394 NPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDH 452
Query: 2501 PCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPP 2560
C +C NTE S+ C C G+++ ED KTC +D C H C++ CVN F C+CP
Sbjct: 453 GCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPE 512
Query: 2561 GFTQHHTACIDNNECGSQPSLC----GAKGICQNTPGSFSCECQRGFSLDATGLNCEDVD 2616
G H D C S G + C ++ SF C+C G+ L G C D
Sbjct: 513 G----HVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 2617 ECDG-NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGS 2675
C +H C+H C N Y C C +G+ +C ++ C + + C N S
Sbjct: 569 VCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNS 628
Query: 2676 YKCACPSGFSFDQFSSACHDVNE 2698
Y C C GF + C E
Sbjct: 629 YICKCSEGFVLAEDGRRCKKCTE 651
Score = 211 bits (538), Expect = 6e-54
Identities = 135/460 (29%), Positives = 197/460 (42%), Gaps = 60/460 (13%)
Query: 1246 CMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGE 1305
C + C C N GSY C C +GY L D +C D C C+ C N+PG
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPGS 300
Query: 1306 YRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC 1365
+ C CY G+ + D K C+ V+ C ++ C EC N GS++C C G+++ C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 1366 TDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINA 1423
T +D C H C C+N S+ C C +G+ N K C ++ C+ C
Sbjct: 360 TKIDYCASSNHGC--QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC--EH 415
Query: 1424 QCVNTPGSYRCACSEGFTGD--GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 1481
+CVN SY C C G+T D G TCS VD CA+ + CE CLN ++ C+C GF
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFL 474
Query: 1482 PASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN 1541
D ++C +D C + +C N+ F C C +G+ L G C +D CA +
Sbjct: 475 INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDH 534
Query: 1542 CVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1601
CV++ + C C + L G C
Sbjct: 535 GCEHSCVSSEDSFVCQCFEGYILREDGKTC------------------------------ 564
Query: 1602 SRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC 1661
R C ++ + C VNS + YT C EGFR + ED C+ +C
Sbjct: 565 RRKDVCQAIDHGCEHIC-----VNSDDSYT-CECLEGFR------LAEDGKRCRR-KDVC 611
Query: 1662 QGGN------CINTFGSFQCECPQGYYLSEDTRICEDIDE 1695
+ + C+N S+ C+C +G+ L+ED R C+ E
Sbjct: 612 KSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 207 bits (528), Expect = 9e-53
Identities = 119/380 (31%), Positives = 167/380 (43%), Gaps = 40/380 (10%)
Query: 2187 CINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPG 2246
C+N GSF C+C GY L G RCV D C+ N C N GS+ C C+EGF
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALN 353
Query: 2247 P-MMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
P C I+ CA + C C+NT SY C C G+ L D+K C+ ++ CA C
Sbjct: 354 PDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC 413
Query: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2365
E C N+ ++ C C G P+G+ C + C + CE C+N S+ C+C
Sbjct: 414 EHE---CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQC 469
Query: 2366 NEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELC 2425
+EGF + C +R C H CE
Sbjct: 470 SEGFLINEDLKTC--SRVDYCLLS-----------------------------DHGCEYS 498
Query: 2426 PLPGTAQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTT 2482
+ + CP G +DG+ +D C + + C + C+++ SF C C GY
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYIL 557
Query: 2483 DISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN 2542
G +C D C C +IC N++ SY C C G+ L EDGK C+ D C++ H
Sbjct: 558 REDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG 617
Query: 2543 CQFLCVNTLGGFTCKCPPGF 2562
C+ +CVN + CKC GF
Sbjct: 618 CEHICVNNGNSYICKCSEGF 637
Score = 207 bits (527), Expect = 1e-52
Identities = 138/452 (30%), Positives = 205/452 (45%), Gaps = 55/452 (12%)
Query: 1341 CENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 1400
C N GS++C C+ GY + T C D C + HNC+ C+N+PGSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 1401 --GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAEN 1456
+G +C+ +D C++ H C +CVN GSY C C EGF D TC+ +D CA +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCE--HECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASS 368
Query: 1457 INLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCI 1516
+ C++ +C+N +Y C C GFT D ++C+ I+ C+ C N+ ++C
Sbjct: 369 NHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCR 427
Query: 1517 CDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRV 1576
C GY LD G C+ +D CA + LC+NT + C C F +N C +RV
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC--SRV 485
Query: 1577 GNCYLKFGPRGDGSLSCNTEIGVGVSRS-SCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
C L SC V + RS +C C G + +TC ++S C
Sbjct: 486 DYCLLS---DHGCEYSC-----VNMDRSFACQCPEGHVLRSDGKTCAKLDS------CAL 531
Query: 1636 GEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDE 1695
G+ C+ +C+++ SF C+C +GY L ED + C D
Sbjct: 532 GD--------------HGCEH--------SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 1696 CFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF 1755
C A C C N+ +YTC C + G C RK C +++G CE+
Sbjct: 570 CQAIDHGC-EHICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVCKSTHHG--CEHICVN 624
Query: 1756 NVTKRMCCCTYNVGKAWN-KPCEPCPTPGTAD 1786
N +C C+ A + + C+ C T G D
Sbjct: 625 NGNSYICKCSEGFVLAEDGRRCKKC-TEGPID 655
Score = 207 bits (527), Expect = 1e-52
Identities = 127/450 (28%), Positives = 203/450 (45%), Gaps = 55/450 (12%)
Query: 971 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD---EDECIHPVPGKFRMDACCC 1027
C+N GS+ C C +G L+ C R++ D E C++ VPG F C C
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTC---RIQDLCAMEDHNCEQLCVN-VPGSF---VCQC 305
Query: 1028 AVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG 1087
G A + + C ++ C + C +
Sbjct: 306 YSGYALAEDGKRCVA-------------------------------VDYCASENHGCEH- 333
Query: 1088 KCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYE 1147
+C N GS+ C+C+ GFAL+ +++ CT ID C S C CVNT S+ C C +G+
Sbjct: 334 ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC-QHECVNTDDSYSCHCLKGFT 392
Query: 1148 SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLS 1207
K C I+ C N C CVN E S+ C C G+ L P+ + C ++ C+
Sbjct: 393 LN-PDKKTCRRINYCALNKPGCE-HECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQ 450
Query: 1208 DNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1267
D+ C C+N ++ C C+ G+ D + C+ +D C++ + GC+ C N + S+ C
Sbjct: 451 DHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ 509
Query: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
C EG+ L DG++CA +D C C+ C + + C C++G++ D KTC +
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 1328 ECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNI 1387
C + C C N+ S+ C C G+ + + C D C+ H C+ C+N
Sbjct: 569 VCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCE--HICVNN 625
Query: 1388 PGSFKCSCREGWI--GNGIKCIDLDECSNG 1415
S+ C C EG++ +G +C +C+ G
Sbjct: 626 GNSYICKCSEGFVLAEDGRRC---KKCTEG 652
Score = 206 bits (524), Expect = 3e-52
Identities = 123/443 (27%), Positives = 184/443 (41%), Gaps = 50/443 (11%)
Query: 2298 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2357
C+ H+C C N+ G+++C C G D C ++ C + CE CVN+
Sbjct: 242 CSTLEHNCAH---FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNV 297
Query: 2358 IGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRG 2417
GS+ C+C G+ + G C+ + C G
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCV---------------------------AVDYCASENHG 330
Query: 2418 WGHQCELCPLPGTAQYKKICPHGPGYTTDGRD---IDECKVMPNLCTNGQCINTMGSFRC 2474
H+C + Y C G D + ID C + C + +C+NT S+ C
Sbjct: 331 CEHEC----VNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSC 385
Query: 2475 FCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLD 2534
C G+T + +C ++ C+ + C + C N E SY C C RGY L +GKTC +D
Sbjct: 386 HCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVD 445
Query: 2535 ECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLC-----GAKGICQ 2589
C + H C+ LC+NT F C+C GF + D C S+ C G + C
Sbjct: 446 HCAQQDHGCEQLCLNTEDSFVCQCSEGFLINE----DLKTC-SRVDYCLLSDHGCEYSCV 500
Query: 2590 NTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
N SF+C+C G L + G C +D C G+H C+H C + + C C +GYI
Sbjct: 501 NMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Query: 2649 WNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNY 2708
C ++ C + C N+ SY C C GF + C + C S+ + C +
Sbjct: 561 GKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH 620
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQG 2731
C N Y+C C G+ G
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDG 643
Score = 190 bits (482), Expect = 2e-47
Identities = 140/458 (30%), Positives = 204/458 (44%), Gaps = 57/458 (12%)
Query: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKL-SPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
CS ++ C CIN PGSY C C G+ L S C ++ C + C LCV++
Sbjct: 242 CSTLEHNCAHF--CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVP 298
Query: 1913 GSYQCICHNGFKASQDQTMCMDVDEC--ERHPCGNGTCKNTVGSYNCLCYPGFELT-HNN 1969
GS+ C C++G+ ++D C+ VD C E H C + C N GSY C C+ GF L
Sbjct: 299 GSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKK 357
Query: 1970 DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP 2029
C ID C+S C++ C N S+ C C +G+ L PD K C N C C
Sbjct: 358 TCTKIDYCAS-SNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE- 414
Query: 2030 GTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 2087
C N+E S+ C C GY + + C ++ C + + C C NT F C C GF
Sbjct: 415 HECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGF 473
Query: 2088 VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDD 2147
+++++ + C +R +C + ++G CE +
Sbjct: 474 LINEDLKTC--SRVDYCLLS-DHG----------------------------CEYSCVNM 502
Query: 2148 EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYT 2207
+ +F CP GH + S T ++ C C + C++++ SF C+C GY L
Sbjct: 503 DRSFACQCPEGH-VLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILRED 560
Query: 2208 GVRCVDTDEC-SIGNPCGNGTCTNVIGSFECNCNEGF---EPGPMMNCEDINECAQNPLL 2263
G C D C +I + C + C N S+ C C EGF E G +D+ C
Sbjct: 561 GKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDV--CKSTHHG 617
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEG 2301
C C+N SY C C G+ L ED + CK +C EG
Sbjct: 618 CEHICVNNGNSYICKCSEGFVLAEDGRRCK---KCTEG 652
Score = 188 bits (478), Expect = 6e-47
Identities = 133/434 (30%), Positives = 186/434 (42%), Gaps = 37/434 (8%)
Query: 467 FSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYK 526
F + G+ V QG I+ + D+C + C C+ S+ C+C GY
Sbjct: 252 FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC-EQLCVNVPGSFVCQCYSGYA 310
Query: 527 QDANGD-CIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGV 584
+G C+ VD C S N +CVN GSY C+CH GF P K+ C ID C +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNH 370
Query: 585 LCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICK 644
C++ CVNTD S+ C C GF L D K C + C C+N + S+ C C
Sbjct: 371 GCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCH 429
Query: 645 PGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
G+ L PNG+ C+ VD C C+N+E SF C C G + D + C
Sbjct: 430 RGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS------ 483
Query: 705 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 764
+ C+ G E C N D F CQ CP E H L S G
Sbjct: 484 ------RVDYCLLSDHGC----EYSCVNMDRSFA--CQ-CP-----EGHVLRSDGKTCA- 524
Query: 765 DGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG 824
++ CAL C + C + S+ C C GY G+ C D C C++
Sbjct: 525 ---KLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH- 579
Query: 825 LCRNTPGSYSCTCPPGYVFRTETETCEDINECES--NPCVNGACRNNLGSFNCECSPGSK 882
+C N+ SY+C C G+ + + C + C+S + C + C NN S+ C+CS G
Sbjct: 580 ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFV 638
Query: 883 LSSTGLICIDSLKG 896
L+ G C +G
Sbjct: 639 LAEDGRRCKKCTEG 652
Score = 182 bits (462), Expect = 4e-45
Identities = 127/468 (27%), Positives = 191/468 (40%), Gaps = 69/468 (14%)
Query: 539 CTSNPCTNGD------CVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCV 592
CT++ C+ + C+N PGSY C+C G+ + C D C C+ CV
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCV 295
Query: 593 NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPN 652
N GSF C C +G+ L DGK CV D C + N C+N DGS+ C C GF L P+
Sbjct: 296 NVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 653 GRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKK 712
+ CT +D C + C+N++ S+ C C G + D + C R Y + K
Sbjct: 356 KKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTC-----RRINYCALNK 410
Query: 713 GVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRD---I 769
C E C N + ++ C G + +G+ +
Sbjct: 411 PGC-----------EHECVNME---------------ESYYCRCHRGYTLDPNGKTCSRV 444
Query: 770 NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT 829
+ CA C +C N S+ C C+ G+ + + C +D CL++ C+ C N
Sbjct: 445 DHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS-CVNM 502
Query: 830 PGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGACRNNLGSFNCECSPGSKLSSTG 887
S++C CP G+V R++ +TC ++ C + C + +C ++ SF C+C G L G
Sbjct: 503 DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDG 561
Query: 888 LICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLAR 947
C K C D CE + C G +RC C +
Sbjct: 562 KTC--RRKDVC--QAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC-----K 612
Query: 948 IKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
CE + CVN+ S+ C+C EG L GR C
Sbjct: 613 STHHGCEHI--------------CVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 182 bits (462), Expect = 4e-45
Identities = 122/401 (30%), Positives = 172/401 (42%), Gaps = 46/401 (11%)
Query: 1990 CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEV 2049
C N GS+ C C +GY L D C + C +C C N+ GSF C C GY +
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 2050 KSEN--CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTN 2107
+ C+ ++ C + + C C N G + C C GF L+ + + C
Sbjct: 312 AEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC----------- 359
Query: 2108 FENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHD 2167
TK C S G C+ + + ++ C G P
Sbjct: 360 --------------TKIDYCASSNHG------CQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 2168 TREDVNEC-LESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG 2226
R +N C L PG C + +C+N + S+ C C GY LD G C D C+ +
Sbjct: 400 CRR-INYCALNKPG-CEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 2227 TCTNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYAL 2285
C N SF C C+EGF + C ++ C + C + C+N S+ C CP G+ L
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVL 516
Query: 2286 REDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK 2345
R D K C LD CA G H CE C + +F+C C G R DG+ C ++ C+
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEH---SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI 573
Query: 2346 PGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 2386
CE+ CVN SY CEC EGF+ + G C R+ +C
Sbjct: 574 DHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVC 611
Score = 182 bits (461), Expect = 5e-45
Identities = 101/322 (31%), Positives = 145/322 (45%), Gaps = 12/322 (3%)
Query: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGS 2512
C + + C + CIN GS+ C CK GY + T+C D C+ C +C N GS
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS 300
Query: 2513 YQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH--HTACI 2570
+ C C GY L EDGK C +D C ++ H C+ CVN G + C+C GF + C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQ 2629
+ C S S G + C NT S+SC C +GF+L+ C ++ C N C+H C
Sbjct: 361 KIDYCAS--SNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECV 418
Query: 2630 NILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQF 2689
N+ Y C C +GY C + C+ + C NT S+ C C GF ++
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINED 478
Query: 2690 SSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDT 2749
C V+ C S + C Y C N + + C CP G+ G + K +L
Sbjct: 479 LKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCA-----KLDSCALGD 533
Query: 2750 EVDEENALSPEACYECK-INGY 2770
E + +S E + C+ GY
Sbjct: 534 HGCEHSCVSSEDSFVCQCFEGY 555
Score = 181 bits (459), Expect = 9e-45
Identities = 128/447 (28%), Positives = 186/447 (41%), Gaps = 44/447 (9%)
Query: 1941 HPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
H C + C N GSY C C G+ L + I + + C C N GSF C
Sbjct: 247 HNCAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQ 304
Query: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
C GY L DGK C+ + C + C C N +GS+ C C G+ + + C I+
Sbjct: 305 CYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKID 363
Query: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2118
C + C C NT + C C GF L+ + + C R ++C N
Sbjct: 364 YCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTC--RRINYCALN----------- 409
Query: 2119 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2178
PG CE + E ++ C G+ P+ T V+ C +
Sbjct: 410 ------------KPG------CEHECVNMEESYYCRCHRGYTLDPN-GKTCSRVDHCAQQ 450
Query: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECN 2238
C C+NT+ SF C+C G+ ++ C D C + + +C N+ SF C
Sbjct: 451 DHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ 509
Query: 2239 CNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDE 2297
C EG C ++ CA C C+++ S+ C C GY LRED K C+ D
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 2298 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNI 2357
C H CE +C N ++ C C G DG+ C ++ C++ CE+ CVN
Sbjct: 570 CQAIDHGCEH---ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNN 625
Query: 2358 IGSYRCECNEGFQSSSSGTECLDNRQG 2384
SY C+C+EGF + G C +G
Sbjct: 626 GNSYICKCSEGFVLAEDGRRCKKCTEG 652
Score = 157 bits (396), Expect = 2e-37
Identities = 114/440 (25%), Positives = 170/440 (38%), Gaps = 65/440 (14%)
Query: 1465 CLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELD 1524
C+N+PG+Y C C+ G+ SD +C+ D C+ ++ C N+PG F C C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1525 RTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFG 1584
G C +D CA + CVN G Y C C F LNP C ++ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC--TKIDYC----- 365
Query: 1585 PRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN----------------STE 1628
+ C E SC C G +TC +N
Sbjct: 366 --ASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEES 423
Query: 1629 YYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTR 1688
YY C G PN T +D C + C+ C+NT SF C+C +G+ ++ED +
Sbjct: 424 YYCRCHRGYTLDPNGKT--CSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLK 480
Query: 1689 ICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTT 1748
C +D C C +C N ++ C CP ++ + G C + C +G
Sbjct: 481 TCSRVDYCLLSDHGC-EYSCVNMDRSFACQCPEGHVLRSDGKTCAKL--DSCALGDHG-- 535
Query: 1749 CENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD 1808
CE+ + +C C G+
Sbjct: 536 CEHSCVSSEDSFVCQC-----------------------------FEGYILREDGKTCRR 566
Query: 1809 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
D C+ I C + +C+N S+ CEC GF + C D C + + C+ C+
Sbjct: 567 KDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH--ICV 623
Query: 1869 NSPGSYRCECAAGFKLSPNG 1888
N+ SY C+C+ GF L+ +G
Sbjct: 624 NNGNSYICKCSEGFVLAEDG 643
Score = 155 bits (392), Expect = 6e-37
Identities = 127/466 (27%), Positives = 176/466 (37%), Gaps = 79/466 (16%)
Query: 1506 CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLN 1565
C N+PG + C C GY L+ C D CA + LCVN PG + C C + L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
G CV C S + C VN
Sbjct: 313 EDGKRCV------------------------------AVDYCASENHGCEHEC-----VN 337
Query: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
+ Y LC EGF NP ID C CQ C+NT S+ C C +G+ L+
Sbjct: 338 ADGSY-LCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNP 395
Query: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
D + C I+ C + C C N +Y C C Y G C R C + +
Sbjct: 396 DKKTCRRINYCALNKPGC-EHECVNMEESYYCRCHRGYTLDPNGKTCS--RVDHCAQQDH 452
Query: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1805
G CE ++C T + +C GF +
Sbjct: 453 G--CE---------QLCLNTED--------------------SFVCQCSEGFLINEDLKT 481
Query: 1806 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA 1865
+D C C C+N SF C+CP G C +D C+ GD+ C+ +
Sbjct: 482 CSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS- 539
Query: 1866 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
C++S S+ C+C G+ L +G C ++ C I + C H +CV+ SY C C GF+
Sbjct: 540 -CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFR 597
Query: 1925 ASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELTHN 1968
++D C D C+ H C + C N SY C C GF L +
Sbjct: 598 LAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAED 642
Score = 151 bits (382), Expect = 8e-36
Identities = 127/478 (26%), Positives = 184/478 (38%), Gaps = 86/478 (17%)
Query: 779 CANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCP 838
CA+ C N+ GSY C C GY ++ C D C + C+ LC N PGS+ C C
Sbjct: 249 CAH-FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCY 306
Query: 839 PGYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT 897
GY + + C ++ C S N C N GS+ C+C G L+ K T
Sbjct: 307 SGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD--------KKT 358
Query: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVT----- 952
C K + CA+ C + +C +KG T
Sbjct: 359 C-----------------TKIDYCASSNHGCQHECVNTDDSYSCHC----LKGFTLNPDK 397
Query: 953 --CEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDED 1010
C +N C + C + CVN + S++C C G TLD G+ C + D
Sbjct: 398 KTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRV-----------D 445
Query: 1011 ECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPF 1070
C G + C ++ +C E GF D+ T
Sbjct: 446 HCAQQDHG---CEQLCLNTEDSFVCQCSE-----------------GFLINEDLKT---- 481
Query: 1071 YKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 1130
++ C C Y C N SF C+C G L + + C +D C + C
Sbjct: 482 CSRVDYCLLSDHGCEY-SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS- 539
Query: 1131 CVNTPGSFECECFEGY---ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPL 1187
CV++ SF C+CFEGY E G K C D C+ C CVN++ S+ C+C
Sbjct: 540 CVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAIDHGCE-HICVNSDDSYTCECLE 594
Query: 1188 GHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDE 1245
G L+ + C + C + + C + CVN +Y C C+ G+ D + C E
Sbjct: 595 GFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 138 bits (348), Expect = 7e-32
Identities = 88/298 (29%), Positives = 124/298 (41%), Gaps = 22/298 (7%)
Query: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTSN-PCTNGDCVNT 552
ID C + C + C+ T SY C C G+ + + C ++ C N P +CVN
Sbjct: 362 IDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNM 420
Query: 553 PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDG 612
SYYC+CH G+ P + C +D C Q C+ C+NT+ SF C C+ GF + D
Sbjct: 421 EESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDL 479
Query: 613 KNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGH 672
K C D C ++ C+N D SF C C G VL +G+ C +D C
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS 539
Query: 673 CINSEGSFRCDCPPGLAVGMDGRVC--------VDTHMRSTCYGGIKKGVC--VRPFPGA 722
C++SE SF C C G + DG+ C +D C C + F A
Sbjct: 540 CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA 599
Query: 723 VTKSEC----CCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDP 776
C C + +G C+ N + CS G + DGR +C P
Sbjct: 600 EDGKRCRRKDVCKSTHHG----CEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 79.3 bits (194), Expect = 5e-14
Identities = 77/311 (24%), Positives = 111/311 (35%), Gaps = 67/311 (21%)
Query: 87 NVCGSRFHSYCCPGWKTLPGGNQCI-VPICRNS------------------CGDGFCSRP 127
NV GS F C G+ G +C+ V C + C +GF P
Sbjct: 296 NVPGS-FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNP 354
Query: 128 NMCTCSSGQISSTCGSKSIQQC-------SVRCMNGGTCADDHCQCQKGYIGTYCG--QP 178
+ TC+ ++ +C S C+ G T D C++ YC +P
Sbjct: 355 DKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRI---NYCALNKP 411
Query: 179 VCENGCQNGGRCIGPNRCACVYGFT-GPQCERDYRTGPCFTQVNN--QMCQGQLTGIVCT 235
CE+ C N C C G+T P + R C Q + Q+C VC
Sbjct: 412 GCEHECVNMEESY---YCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQ 468
Query: 236 KTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINT 295
C GF+ N C VD C C+ +C+N
Sbjct: 469 -------------------------CSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVNM 502
Query: 296 VGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDG 355
SF C+CP GH + C +D C++ CE C ++ S+ C C GY+ DG
Sbjct: 503 DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDG 561
Query: 356 SRCIDQRTGMC 366
C +R +C
Sbjct: 562 KTC--RRKDVC 570
Score = 70.1 bits (170), Expect = 3e-11
Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 11/166 (6%)
Query: 233 VCTKTLC----CATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGIC 287
V K LC C+T+ H C P C++G+I N C+ D C C
Sbjct: 231 VFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC 290
Query: 288 QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPR 347
+ C+N GSF C+C +G+ +E ++C +D C+ CE EC N GSY C C
Sbjct: 291 EQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHE 348
Query: 348 GYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
G+ + D C T + + N C E C C G
Sbjct: 349 GFALNPDKKTC----TKIDYCASSNHGCQHECVNTDDSYSCHCLKG 390
Score = 67.8 bits (164), Expect = 2e-10
Identities = 69/257 (26%), Positives = 88/257 (34%), Gaps = 49/257 (19%)
Query: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGT- 173
CR C G+ PN TCS C + C C+N T CQC +G++
Sbjct: 426 CR--CHRGYTLDPNGKTCSR---VDHCAQQD-HGCEQLCLN--TEDSFVCQCSEGFLINE 477
Query: 174 ---------YC--GQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNN 222
YC CE C N R C C G
Sbjct: 478 DLKTCSRVDYCLLSDHGCEYSCVNMDRSFA---CQCPEGHVL------------------ 516
Query: 223 QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQ-PQPCRRGFIPNIRTGACQDVDECQ 281
+ G C K CA H C C G+I C+ D CQ
Sbjct: 517 -----RSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQ 571
Query: 282 AIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSY 341
AI C+ C+N+ S+ C C G + +E ++C D C CE C N SY
Sbjct: 572 AIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEH-ICVNNGNSY 629
Query: 342 FCVCPRGYVTSTDGSRC 358
C C G+V + DG RC
Sbjct: 630 ICKCSEGFVLAEDGRRC 646
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 266 bits (681), Expect = 2e-70
Identities = 216/692 (31%), Positives = 283/692 (40%), Gaps = 113/692 (16%)
Query: 809 IDIDECL-VNRLLCDNGLCRNTPGSYSC-------TCPPGYVFRTETETC--EDINEC-- 856
ID DECL + ++ +CR T + C +C G + E ETC ED + C
Sbjct: 454 IDNDECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGI 512
Query: 857 ----ESNPCVNGACRNNLGSFNCECSP--GSKLSSTGLICIDSLKGTCWLNIQDSRCEVN 910
+ C R +CE +P G + L C + G L + + R
Sbjct: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCE---GEEPLIVPEVRRPPE 569
Query: 911 INGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGR 970
A + G S EL + P +D +EC + PG
Sbjct: 570 PAAAPRRVSEAEMAGREALSLGTEAELPNSLPG----------DDQDECLLLPGELCQHL 619
Query: 971 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
C+N+ GS+HC C G +L GR C E P P + A
Sbjct: 620 CINTVGSYHCACFPGFSLQDDGRTC-------------RPEGHPPQPEAPQEPALKSEFS 666
Query: 1031 -AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKC 1089
A T P+P T KD CK C
Sbjct: 667 QVASNTIPLPLPQPNT-------------------------CKDNGPCKQV--------C 693
Query: 1090 RNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI-CVNTPGSFECECFEGYES 1148
GS C C G+A+ + +C DI+EC C G CVNT GSF C E
Sbjct: 694 STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEP 753
Query: 1149 GFMMMKN-CMDIDECERNPLLCRGG-TCVNTEGSFQCD----CPLGHELSPSREDCVDIN 1202
G+ + C D+DEC C+ G C NT+GSF C C G P +CVDIN
Sbjct: 754 GYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDIN 812
Query: 1203 ECSLSDNLCRNG-KCVNMIGTYQCSCNP-----GYQATPDRQGCTDIDECM--IMNGGCD 1254
EC+ CR G C+N +G+Y C NP GY A+ D C D++EC + G
Sbjct: 813 ECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEG 872
Query: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF 1314
C N GSY C C G+ GR C D++EC +P C N G YRC C GF
Sbjct: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
Query: 1315 MASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIG 1374
+ + D K C DVNEC+ EC N GS+ C+C+ GY + + CTD+DEC G
Sbjct: 933 LLAADGKRCEDVNECEAQR---CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 989
Query: 1375 AH-NCDMHASCLNIPGSFKCSCRE---GWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1430
A C CLN+PGS++C+C E NG C D+DEC+ GTH CS C N G
Sbjct: 990 AGILCTFR--CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQG 1047
Query: 1431 SYRC---ACSEGFTG------DGFTCSDVDEC 1453
S+RC C + + TC D EC
Sbjct: 1048 SFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
Score = 266 bits (679), Expect = 3e-70
Identities = 196/627 (31%), Positives = 270/627 (43%), Gaps = 111/627 (17%)
Query: 1026 CCAVGAAWGTECEEC---PKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG 1082
CCA G W + +EC P+ GT++ N C+
Sbjct: 445 CCAAGQQWAIDNDECLEIPESGTED---------------------------NVCRTAQR 477
Query: 1083 MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP-----DLCGSGICVNTPG- 1136
C C + + C A + E D D C IS D CG G+ V G
Sbjct: 478 HC----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
Query: 1137 SFECECFEGYESGFMMMKNC-----MDIDECERNPLLCRGGTCVN-TEGSFQCDCPLGHE 1190
S E GY +M+ C + + E R P V+ E + + LG E
Sbjct: 534 SCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTE 593
Query: 1191 LS-PSREDCVDINECSL-SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-------- 1240
P+ D +EC L LC++ C+N +G+Y C+C PG+ D + C
Sbjct: 594 AELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
Query: 1241 -------------TDIDECMIM-----------NGGCDTQCTNSEGSYECSCSEGYALMP 1276
+ + I NG C C+ GS CSC GYA+M
Sbjct: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
Query: 1277 DGRSCADIDECENNPDICDGGQ-CTNIPGEYRC----LCYDGFMASMDMKTCIDVNECDL 1331
DG SC DI+EC + C G+ C N G + C C G+ ++ C DV+EC +
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY--ALKDGECEDVDECAM 770
Query: 1332 NSNICMFG-ECENTKGSFIC----HCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1386
++ C G C+NTKGSF C C G+ ++ C D++EC + C SC+N
Sbjct: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCIN 829
Query: 1387 IPGSFKCS-----CREGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEG 1439
GS+ C C G+ +G KC+D++EC G H+C C N PGSYRC C G
Sbjct: 830 TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 889
Query: 1440 FTGDGF--TCSDVDEC-AENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS 1496
F D F C DV+EC A LC++ C N G+YRC C GF A+D + C+D++EC
Sbjct: 890 FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
Query: 1497 FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCV-NGLCVNTPGRYE 1555
Q C N+ G + C C GY+L G CTDIDECA + C+N PG Y+
Sbjct: 949 AQRCS--QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQ 1006
Query: 1556 CNCPPD-FQLNPTGVGCVDNRVGNCYL 1581
C CP + + G C D V C L
Sbjct: 1007 CACPEQGYTMTANGRSCKD--VDECAL 1031
Score = 263 bits (672), Expect = 2e-69
Identities = 175/540 (32%), Positives = 244/540 (45%), Gaps = 56/540 (10%)
Query: 1594 NTEIGVGVSRSSC-CCSLG---KAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILE 1649
N G+ + + C CC LG +A G CE+ P + + + EG P + +
Sbjct: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
+ + + S E L D D DEC PG C
Sbjct: 567 PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD-----DQDECLLLPGELCQHLCI 621
Query: 1710 NTLGNYTCICPPEYMQVNGGHNCM--------DMRKSFCYRSYNGTTCENELPFNVTKRM 1761
NT+G+Y C C P + + G C + + +S N +P + +
Sbjct: 622 NTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPN 681
Query: 1762 CCCTYNVGKAWNKPC-EPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 1820
C N PC + C T G + IC PG+ DI+EC C+
Sbjct: 682 TCKD-------NGPCKQVCSTVGGS---AICSCFPGYAIMADGVSCEDINECVTDLHTCS 731
Query: 1821 NGV-CINQIGSFRC----ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
G C+N +GSF C C G++ D CED+DEC+ G + CQ C N+ GS+
Sbjct: 732 RGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
Query: 1876 CE----CAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQC-----ICHNGFKA 1925
C+ C GF P G CVD NEC + C G C++ GSY C IC G+ A
Sbjct: 790 CQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA 849
Query: 1926 SQDQTMCMDVDECER--HPCGNG-TCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFF 1981
S D T C+DV+ECE H CG G C N GSY C C GF+ C+D++EC +
Sbjct: 850 SDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASP 909
Query: 1982 GQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRC 2041
G++C++ C N +GS++C C G+ L DGK C D NEC A CS C N+ GS++C
Sbjct: 910 GRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQC 965
Query: 2042 ICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCP-PGFVLSDNGRRCFD 2098
C GY++ + C DI+EC + I C N PG +QC CP G+ ++ NGR C D
Sbjct: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Score = 255 bits (651), Expect = 5e-67
Identities = 177/522 (33%), Positives = 240/522 (45%), Gaps = 68/522 (13%)
Query: 2170 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2229
+D +ECL PG CINT GS+ C C G++L G C
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 2230 NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 2289
+ N P P C+D C Q C GS C+C GYA+ D
Sbjct: 663 SEFSQVASNTIPLPLPQPN-TCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADG 714
Query: 2290 KMCKDLDECAEGLHDCESRGMMCKNLIGTFMC----ICPPGMARRPDGEGCVDENECRTK 2345
C+D++EC LH C SRG C N +G+F C C PG A + DGE C D +EC
Sbjct: 715 VSCEDINECVTDLHTC-SRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMG 771
Query: 2346 PGICENG-RCVNIIGSYRCE----CNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
C+ G C N GS+ C+ C +GF G C+D + +E C+ S
Sbjct: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEP----CRPGFS 826
Query: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKVMP 2457
N V + C+ PL IC G + DG D++EC+
Sbjct: 827 CINTV------------GSYTCQRNPL--------ICARGYHASDDGTKCVDVNECETGV 866
Query: 2458 NLCTNGQ-CINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP-KPCNYICKNTEGSYQC 2515
+ C GQ C N GS+RC CK G+ D G CID++EC SP + C + C+NT GSY+C
Sbjct: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC 926
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNN 2573
SC G++L DGK C+D++EC+ ++ C C N G + C C G+ + C D +
Sbjct: 927 SCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDID 984
Query: 2574 ECGSQPS-LCGAKGICQNTPGSFSCEC-QRGFSLDATGLNCEDVDECD-GNHRCQHG--C 2628
EC LC + C N PGS+ C C ++G+++ A G +C+DVDEC G H C C
Sbjct: 985 ECAQGAGILCTFR--CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETC 1042
Query: 2629 QNILGGYRC---GCPQGYIQ----HYQWNQCVDENECSNPNA 2663
NI G +RC CP Y+Q + C D EC N A
Sbjct: 1043 HNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPA 1084
Score = 246 bits (628), Expect = 2e-64
Identities = 175/585 (29%), Positives = 255/585 (43%), Gaps = 80/585 (13%)
Query: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR-----QGLCFAEVLQ 2392
D++EC PG C+N +GSY C C GF G C + +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 2393 TICQMASSSRNL-VTKSECCCDGGRGWGHQC-ELCPLPGTAQYKKICPHGPGYT--TDG- 2447
Q+AS++ L + + C D G C ++C G + IC PGY DG
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNG-----PCKQVCSTVGGSA---ICSCFPGYAIMADGV 715
Query: 2448 --RDIDECKVMPNLCTNGQ-CINTMGSFRCF----CKVGYTTDISGTSCIDLDECSQSPK 2500
DI+EC + C+ G+ C+NT+GSF C+ C+ GY + C D+DEC+
Sbjct: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDGECEDVDECAMGTH 773
Query: 2501 PCN--YICKNTEGSYQCS----CPRGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNTLG 2552
C ++C+NT+GS+ C C G++ +G C D++EC + C+ F C+NT+G
Sbjct: 774 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVG 832
Query: 2553 GFTCK-----CPPGF--TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL 2605
+TC+ C G+ + T C+D NEC + CG +C N PGS+ C+C+ GF
Sbjct: 833 SYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 892
Query: 2606 DATGLNCEDVDEC--DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2663
DA G C DV+EC CQH C+N LG YRC C G++ +C D NEC
Sbjct: 893 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 952
Query: 2664 CGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKN-PCNYGCSNTEGGYLCGCP 2722
S C N GSY+C C G+ + C D++EC+ C + C N G Y C CP
Sbjct: 953 --SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP 1010
Query: 2723 -PGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGYSKKDSRQKRSI 2781
GY G + +E AL C E + + R R
Sbjct: 1011 EQGYTMTANGRSCKDV---------------DECALGTHNCSEAETCHNIQGSFRCLRFE 1055
Query: 2782 HEPDPTAVEQISLESV---DMDSPVNMKFNLSH--------LGSKEHILELRPAIQPLNN 2830
P+ V + E D N ++H L HI + PA +
Sbjct: 1056 CPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGD 1115
Query: 2831 HIRYVISQGNDDSVF---RIHQRNGLSYLHTAKKKLMPGTYTLEI 2872
I I +GN++ F R++ G+ YL A L P + L++
Sbjct: 1116 TIALNIIKGNEEGYFGTRRLNAYTGVVYLQRA--VLEPRDFALDV 1158
Score = 235 bits (600), Expect = 4e-61
Identities = 165/517 (31%), Positives = 224/517 (43%), Gaps = 100/517 (19%)
Query: 1808 DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC------------------- 1848
D DEC +PG +CIN +GS+ C C GFS D C
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 1849 EDIDECSN-------GDNLCQRNAD----CINSPGSYRCECAAGFKLSPNG-ACVDRNEC 1896
E SN N C+ N C GS C C G+ + +G +C D NEC
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
Query: 1897 LEIPNVCSHG-LCVDLQGSYQC----ICHNGFKASQDQTMCMDVDECE--RHPCGNG-TC 1948
+ + CS G CV+ GS+ C C G+ + C DVDEC H C G C
Sbjct: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLC 781
Query: 1949 KNTVGSYNC----LCYPGFELTHNNDCLDIDECSSFFGQVCRNG-RCFNEIGSFKC---- 1999
+NT GS+ C C GF +C+DI+EC+S + CR G C N +GS+ C
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTS-LSEPCRPGFSCINTVGSYTCQRNP 840
Query: 2000 -LCNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCICPPGY--EVKSENCI 2055
+C GY + DG C+D NEC C G C NL GS+RC C G+ + CI
Sbjct: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Query: 2056 DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSV 2115
D+NEC P +C NT G ++C C GF+L+ +G+RC D + E +CS
Sbjct: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC------EAQRCSQ 954
Query: 2116 PKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNEC 2175
C+ + G ++Q C G+ H T D++EC
Sbjct: 955 E-----------CANIYG----------------SYQCYCRQGYQLAEDGH-TCTDIDEC 986
Query: 2176 LESPGICSNGQCINTDGSFRCECP-MGYNLDYTGVRCVDTDECSIG-NPCGNG-TCTNVI 2232
+ GI +C+N GS++C CP GY + G C D DEC++G + C TC N+
Sbjct: 987 AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQ 1046
Query: 2233 GSFEC---NCNEGFEPGPMMNCE-----DINECAQNP 2261
GSF C C + CE D EC +P
Sbjct: 1047 GSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
Score = 211 bits (537), Expect = 8e-54
Identities = 159/538 (29%), Positives = 225/538 (41%), Gaps = 114/538 (21%)
Query: 810 DIDECLV-NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE----------------- 851
D DECL+ LC + LC NT GSY C C PG+ + + TC
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 852 ----------------DINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
N C+ N C GS C C PG + + G+ C D
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI-- 720
Query: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCED 955
+ C +++ + C TLG+ C C G A +K CED
Sbjct: 721 ---------NECVTDLHTCSRGEHCVNTLGSF------HCYKALTCEPGYA-LKDGECED 764
Query: 956 VNECEVFPGVC-PNGRCVNSKGSFHCE----CPEGLTLDGTGRVCLDIRMEQCYLKWDED 1010
V+EC + C P C N+KGSF+C+ C +G D G C+DI +
Sbjct: 765 VDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDI-----------N 812
Query: 1011 ECI---HPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTG 1067
EC P F +C VG+ C+ P +C RG ++ G
Sbjct: 813 ECTSLSEPCRPGF---SCINTVGS---YTCQRNP--------LICARGYHASDDGTKCV- 857
Query: 1068 RPFYKDINECKAFPGMCTYGK-CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC 1126
D+NEC+ C G+ C N GS++C C +GF D R C D++EC SP
Sbjct: 858 -----DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
Query: 1127 GSGICVNTPGSFECECFEGYESGFMMM---KNCMDIDECERNPLLCRGGTCVNTEGSFQC 1183
C NT GS+ C C SGF++ K C D++ECE C N GS+QC
Sbjct: 913 CQHTCENTLGSYRCSC----ASGFLLAADGKRCEDVNECEAQRC---SQECANIYGSYQC 965
Query: 1184 DCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSC-NPGYQATPDRQGCTD 1242
C G++L+ C DI+EC+ + +C+N+ G+YQC+C GY T + + C D
Sbjct: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Query: 1243 IDECMIMNGGCD--TQCTNSEGSYEC---SCSEGYALMP----DGRSCADIDECENNP 1291
+DEC + C C N +GS+ C C Y + + +C D EC+N+P
Sbjct: 1026 VDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
Score = 202 bits (513), Expect = 5e-51
Identities = 141/423 (33%), Positives = 194/423 (45%), Gaps = 68/423 (16%)
Query: 471 VGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGR-CIPTVSSYRC----ECNMGY 525
VGG+ + + G I + + I+ C + C G C+ T+ S+ C C GY
Sbjct: 696 VGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 755
Query: 526 KQDANGDCIDVDECT--SNPCTNGD-CVNTPGSYYC----KCHAGFQRTPTKQACIDIDE 578
+G+C DVDEC ++ C G C NT GS+YC +C GF + P C+DI+E
Sbjct: 756 ALK-DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINE 813
Query: 579 CIQNGVLCKNG-RCVNTDGSFQC-----ICNAGFELTTDGKNCVDHDECTT-TNMCLNG- 630
C C+ G C+NT GS+ C IC G+ + DG CVD +EC T + C G
Sbjct: 814 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
Query: 631 MCINEDGSFKCICKPGFVLAPNGRYCTDVDEC-QTPGICMNGHCINSEGSFRCDCPPGLA 689
+C N GS++C CK GF GR C DV+EC +PG C N+ GS+RC C G
Sbjct: 874 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFL 933
Query: 690 VGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNS 749
+ DG+ C D + EC + C A
Sbjct: 934 LAADGKRCEDVN-------------------------EC--------EAQRCSQECANIY 960
Query: 750 AEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNC-NSGYEPDASG 805
+ C G + DG DI+ECA I C N+ GSY+C C GY A+G
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 806 RNCIDIDECLVNRLLCDNG-LCRNTPGSYSCT---CPPGYVFRTETE----TCEDINECE 857
R+C D+DEC + C C N GS+ C CPP YV ++T+ TC D EC+
Sbjct: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
Query: 858 SNP 860
++P
Sbjct: 1081 NSP 1083
Score = 201 bits (511), Expect = 9e-51
Identities = 169/618 (27%), Positives = 227/618 (36%), Gaps = 154/618 (24%)
Query: 2276 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI-------CPPGMA 2328
E C G D C ++ E + C + C C+ C G+
Sbjct: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC--------CVSYLQEKSCMAGVL 494
Query: 2329 RRPDGEGC--VDENECRTKPGICENGRCVNIIG--------SYRCECNE--GFQSSSSGT 2376
+GE C D + C GI +C + G CE N G+ +
Sbjct: 495 GAKEGETCGAEDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
Query: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
C + + L EV + A+ R V+++E G + EL
Sbjct: 551 SCCEGEEPLIVPEVRRPPEPAAAPRR--VSEAEMAGREALSLGTEAEL------------ 596
Query: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC-----ID 2491
P+ + G D DEC ++P CINT+GS+ C C G++ G +C
Sbjct: 597 -PN----SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPP 651
Query: 2492 LDECSQSPK---------------------------PCNYICKNTEGSYQCSCPRGYVLQ 2524
E Q P PC +C GS CSC GY +
Sbjct: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM 711
Query: 2525 EDGKTCKDLDECQTKQHNCQ--FLCVNTLGGFTC----KCPPGFTQHHTACIDNNECGSQ 2578
DG +C+D++EC T H C CVNTLG F C C PG+ C D +EC
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMG 771
Query: 2579 PSLCGAKGICQNTPGSFSCE---------------------------------------- 2598
C +CQNT GSF C+
Sbjct: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTV 831
Query: 2599 -----------CQRGFSLDATGLNCEDVDECD-GNHRCQHG--CQNILGGYRCGCPQGYI 2644
C RG+ G C DV+EC+ G HRC G C N+ G YRC C G+
Sbjct: 832 GSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ 891
Query: 2645 QHYQWNQCVDENEC-SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
+ C+D NEC ++P +C NTLGSY+C+C SGF C DVNEC + +
Sbjct: 892 RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR 951
Query: 2704 NPCNYGCSNTEGGYLCGCPPGYYRVGQGH-------CVSGMGFNKGQYLSLDTEVDEENA 2756
C+ C+N G Y C C GY GH C G G + L+ + A
Sbjct: 952 --CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGI-LCTFRCLNVPGSYQCA 1008
Query: 2757 LSPEACYECKINGYSKKD 2774
PE Y NG S KD
Sbjct: 1009 -CPEQGYTMTANGRSCKD 1025
Score = 200 bits (508), Expect = 2e-50
Identities = 177/646 (27%), Positives = 245/646 (37%), Gaps = 142/646 (21%)
Query: 1176 NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK---CVNMIGTYQCSCNPGYQ 1232
+T+ + C G + + ++C++I E DN+CR + CV+ + C
Sbjct: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGA 496
Query: 1233 ATPDRQGCTDIDECMI-MNGGCDTQC--------------TNSEGSYEC-----SCSEGY 1272
+ G D D C I + C C +N Y C SC EG
Sbjct: 497 KEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGE 556
Query: 1273 -------------------------------------ALMPDGRSCADIDECENNPDICD 1295
A +P+ D DEC P
Sbjct: 557 EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELC 616
Query: 1296 GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN---ECDLNSNICMFGECENTKGSFICHC 1352
C N G Y C C+ GF D +TC + + + E + I
Sbjct: 617 QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI--- 673
Query: 1353 QLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--IGNGIKCIDLD 1410
+ + T C D C+ C + GS CSC G+ + +G+ C D++
Sbjct: 674 --PLPLPQPNT-CKDNGPCK---------QVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
Query: 1411 ECSNGTHQCSINAQCVNTPGSYRC----ACSEGFTGDGFTCSDVDECAENINLCENG-QC 1465
EC H CS CVNT GS+ C C G+ C DVDECA + C+ G C
Sbjct: 722 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLC 781
Query: 1466 LNVPGAYRCE----CEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHC---- 1515
N G++ C+ C GF + +C DI+EC S C G +C N G + C
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
Query: 1516 -ICDDGYELDRTGGNCTDIDECADPIN-CVNG-LCVNTPGRYECNCPPDFQLNPTGVGCV 1572
IC GY G C D++EC ++ C G +C N PG Y C+C FQ + G GC+
Sbjct: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Query: 1573 DNRVGNCYLKFGPRGDGSLSCNT-EIGVGVSRSSCCCS-LGKAWGNPCETCPPVNSTEYY 1630
D V C+ G L +T E +G R SC L A G CE
Sbjct: 901 D--VNECWAS-----PGRLCQHTCENTLGSYRCSCASGFLLAADGKRCE----------- 942
Query: 1631 TLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
D++EC+ C C N +GS+QC C QGY L+ED C
Sbjct: 943 -------------------DVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLAEDGHTC 980
Query: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPE-YMQVNGGHNCMDM 1735
DIDEC G+ C N G+Y C CP + Y G +C D+
Sbjct: 981 TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1026
Score = 199 bits (505), Expect = 4e-50
Identities = 206/731 (28%), Positives = 281/731 (38%), Gaps = 130/731 (17%)
Query: 246 AWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPA 305
AW P P +PQ +P+ D + +IP G+ T E C A
Sbjct: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
Query: 306 GHKQSETTQKCEDIDECSIIPGICETGE---CSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
G + + +C +I E +C T + C + + C+ G + + +G C +
Sbjct: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKEGETCGAED 506
Query: 363 TGMCFSGLVN---GRCAQELPGRMTKMQC----------------CCEPGRCWGIGTI-- 401
C L C L R C CCE + +
Sbjct: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
Query: 402 ---PEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGN----------G 448
P A P R SE + L +G S PG G G
Sbjct: 567 PPEPAAAPRRVSEA-EMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVG 625
Query: 449 NGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITG--LTILNQTIDICKHHANLCL 506
+ + GF G P G Q P + + + TI + N C
Sbjct: 626 SYHCACFPGFSLQDDGRTCRPE-GHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
Query: 507 -NGRCIPTVS----SYRCECNMGYKQDANG-DCIDVDECTSN--PCTNGD-CVNTPGSYY 557
NG C S S C C GY A+G C D++EC ++ C+ G+ CVNT GS++
Sbjct: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFH 744
Query: 558 C----KCHAGFQRTPTKQACIDIDECIQNGVLCKNG-RCVNTDGSFQCI----CNAGFEL 608
C C G+ + C D+DEC C+ G C NT GSF C C GF
Sbjct: 745 CYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
Query: 609 TTDGKNCVDHDECTT-TNMCLNGM-CINEDGSFKC-----ICKPGFVLAPNGRYCTDVDE 661
+G NCVD +ECT+ + C G CIN GS+ C IC G+ + +G C DV+E
Sbjct: 803 DPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
Query: 662 CQTPGI--CMNGH-CINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRP 718
C+T G+ C G C N GS+RCDC G GR C+D +
Sbjct: 862 CET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE---------------- 904
Query: 719 FPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALD 775
C A+P G CQ + C+SG + DG+ D+NEC +
Sbjct: 905 ----------CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--E 948
Query: 776 PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSC 835
C+ C N+ GSY+C C GY+ G C DIDEC + C N PGSY C
Sbjct: 949 AQRCSQE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1007
Query: 836 TCP-PGYVFRTETETCEDINECE--SNPCVNG-ACRNNLGSFNC---ECSPG----SKLS 884
CP GY +C+D++EC ++ C C N GSF C EC P SK
Sbjct: 1008 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTK 1067
Query: 885 STGLICIDSLK 895
C D L+
Sbjct: 1068 CERTTCHDFLE 1078
Score = 183 bits (465), Expect = 2e-45
Identities = 189/699 (27%), Positives = 267/699 (38%), Gaps = 140/699 (20%)
Query: 1265 ECSCSEGYALMPDGRSCADIDECENNPDICDGGQ---CTNIPGEYRCLCYDGFMASMDMK 1321
E C+ G D C +I E ++C Q C + E C+ G + + + +
Sbjct: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKEGE 500
Query: 1322 TC--IDVNECDLN-----SNICMFGECENTKG-SFICHCQLGYSVKKGTTGCTDVDECEI 1373
TC D + C ++ + C G +G S + LGY C + +E I
Sbjct: 501 TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
Query: 1374 GAH--------NCDMHASCLNIPGSFKCSC-REGWIGNGIKCIDLDECSNGTHQCSINAQ 1424
S + G S E + N + D DEC + +
Sbjct: 561 VPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHL- 619
Query: 1425 CVNTPGSYRCACSEGFT--GDGFTC------------------SDVDECAENI------- 1457
C+NT GSY CAC GF+ DG TC S+ + A N
Sbjct: 620 CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQ 679
Query: 1458 -NLC-ENGQCLNV----PGAYRCECEMGFTPASDSRSCQDIDECSFQ-NICVFGT-CNNL 1509
N C +NG C V G+ C C G+ +D SC+DI+EC + C G C N
Sbjct: 680 PNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNT 739
Query: 1510 PGMFHCI----CDDGYELDRTGGNCTDIDECADPIN-CVNG-LCVNTPGRYECN----CP 1559
G FHC C+ GY L G C D+DECA + C G LC NT G + C C
Sbjct: 740 LGSFHCYKALTCEPGYALK--DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCM 797
Query: 1560 PDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE 1619
F +P G CVD + C P G NT R+ C+ G
Sbjct: 798 DGFLQDPEG-NCVD--INECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG-------- 846
Query: 1620 TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECP 1678
++++ T C D++EC+ C +G C N GS++C+C
Sbjct: 847 ----YHASDDGTKCV---------------DVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
Query: 1679 QGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKS 1738
G+ R C D++EC+A PG TC NTLG+Y C C ++ G C D+ +
Sbjct: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
Query: 1739 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFT 1798
R C E C Y ++ C
Sbjct: 948 EAQR------CSQE---------CANIY------------------GSYQCYCRQGYQLA 974
Query: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNG 1857
D HT DIDEC + GI C+N GS++C CP G++ C+D+DEC+ G
Sbjct: 975 EDGHT--CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1032
Query: 1858 DNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNEC 1896
+ C C N GS+RC F+ PN V + +C
Sbjct: 1033 THNCSEAETCHNIQGSFRC---LRFECPPNYVQVSKTKC 1068
Score = 96.7 bits (239), Expect = 3e-19
Identities = 94/386 (24%), Positives = 137/386 (35%), Gaps = 73/386 (18%)
Query: 25 GTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLR 84
G +P+ PP+P PQ P + + S P + + +
Sbjct: 641 GRTCRPEGHPPQPEAPQEPALKSEFSQVASN---TIPLPLPQPNTCKDNGPCKQVCSTVG 697
Query: 85 GPNVCGSRFHSYCCPGWKTLPGG------NQCIVPI--------CRNSCGDGFCSRPNMC 130
G +C C PG+ + G N+C+ + C N+ G C +
Sbjct: 698 GSAICS------CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKA--L 749
Query: 131 TCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH-CQCQKGYIGTYCGQPVCENGCQNG-G 188
TC G + + +C+ M TC CQ KG Q + Q+ G
Sbjct: 750 TCEPGYALKDGECEDVDECA---MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 806
Query: 189 RCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG 248
C+ N C + + PC G C T+ T
Sbjct: 807 NCVDINECTSL-------------SEPC------------RPGFSCINTVGSYT------ 835
Query: 249 HPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAGH 307
C P C RG+ + C DV+EC+ C +G C N GS+ C C AG
Sbjct: 836 -----CQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
Query: 308 KQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCF 367
++ + C D++EC PG C NT+GSY C C G++ + DG RC D C
Sbjct: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCED--VNECE 948
Query: 368 SGLVNGRCAQELPGRMTKMQCCCEPG 393
+ RC+QE QC C G
Sbjct: 949 A----QRCSQECANIYGSYQCYCRQG 970
Score = 94.0 bits (232), Expect = 2e-18
Identities = 91/295 (30%), Positives = 116/295 (39%), Gaps = 60/295 (20%)
Query: 89 CGSRFHSYCCPGW--KTLPGGNQCIVPICRNSCGDGFCSRP-------NMCT-----CSS 134
C H+ C PG+ + G C R C DGF P N CT C
Sbjct: 768 CAMGTHT-CQPGFLCQNTKGSFYCQA---RQRCMDGFLQDPEGNCVDINECTSLSEPCRP 823
Query: 135 G-QISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG---CQNGGRC 190
G +T GS + Q+ + C G +DD +C CE G C G C
Sbjct: 824 GFSCINTVGSYTCQRNPLICARGYHASDDGTKC--------VDVNECETGVHRCGEGQVC 875
Query: 191 I---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
G RC C GF +RD C VN C A+ GR
Sbjct: 876 HNLPGSYRCDCKAGF-----QRDAFGRGCI-DVNE----------------CWASPGRLC 913
Query: 248 GHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H CE + C GF+ C+DV+EC+A C C N GS++C C G
Sbjct: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQG 970
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP-RGYVTSTDGSRCID 360
++ +E C DIDEC+ GI T C N GSY C CP +GY + +G C D
Sbjct: 971 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Score = 59.7 bits (143), Expect = 4e-08
Identities = 67/264 (25%), Positives = 94/264 (35%), Gaps = 59/264 (22%)
Query: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSK--SIQQCSV---RCMNGGTC----ADDHCQ 165
C N+ G C R N C+ G +S G+K + +C RC G C C
Sbjct: 827 CINTVGSYTCQR-NPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD 885
Query: 166 CQKGY----IGTYC-------GQP--VCENGCQNGGRCIGPNRCACVYGFT--------- 203
C+ G+ G C P +C++ C+N +G RC+C GF
Sbjct: 886 CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCEN---TLGSYRCSCASGFLLAADGKRCE 942
Query: 204 ----------GPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCAT-IGRAWGHPCE 252
+C Y + C+ + Q+ + G CT CA G C
Sbjct: 943 DVNECEAQRCSQECANIYGSYQCYCRQGYQLAED---GHTCTDIDECAQGAGILCTFRCL 999
Query: 253 MCPAQPQPC--RRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFEC---RCPAG 306
P Q +G+ +C+DVDEC C + C N GSF C CP
Sbjct: 1000 NVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1059
Query: 307 HKQSETTQ----KCEDIDECSIIP 326
+ Q T+ C D EC P
Sbjct: 1060 YVQVSKTKCERTTCHDFLECQNSP 1083
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 254 bits (648), Expect = 1e-66
Identities = 151/423 (35%), Positives = 208/423 (49%), Gaps = 35/423 (8%)
Query: 1199 VDINECSLSDNLCR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECM--IMNGGCDT 1255
VD++ECS + C + C N +Y+C C PGY+ + + C DIDEC NGGC
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKG--EGKQCEDIDECENDYYNGGCVH 89
Query: 1256 QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFM 1315
+C N G+Y C+C +G+ L DG +C D+DEC++N C C N G Y C C+ GF
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 1316 ASMDMKTCIDVNECDLN--------SNICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 1367
S + TCI + +N ++IC E KG C C+ G+ + + CT
Sbjct: 149 LSDNQHTCIHRSNEGMNCMNKDHGCAHICR----ETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 1368 VDECEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQC 1425
C G C SC + C C + + +G CI+ +NG + C
Sbjct: 205 T--CNYGNGGCQH--SCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNG----GCDRTC 256
Query: 1426 VNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPA 1483
+T RC+C GFT DG TC D++EC N C++ C N G++ C C G+
Sbjct: 257 KDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF-CRNTVGSFECGCRKGYKLL 315
Query: 1484 SDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCV 1543
+D R+CQDIDECSF+ C C N PG F C+C GY L T +C D+DEC+
Sbjct: 316 TDERTCQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGTT-HCGDVDECSMSNGSC 373
Query: 1544 NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR 1603
+ CVNT G YEC CPP +L+ G CV+ G C + LSC+ GV
Sbjct: 374 DQGCVNTKGSYECVCPPGRRLHWNGKDCVE--TGKCLSRAKTSPRAQLSCSKAGGVESCF 431
Query: 1604 SSC 1606
SC
Sbjct: 432 LSC 434
Score = 207 bits (526), Expect = 2e-52
Identities = 144/427 (33%), Positives = 188/427 (44%), Gaps = 38/427 (8%)
Query: 1933 MDVDECER--HPCG-NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSS-FFGQVCRNG 1988
+DVDEC C + C+NT SY CLC PG++ C DIDEC + ++ C +
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVH- 89
Query: 1989 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE 2048
C N G+++C C +G+ L DG NC+D +EC G C C N GS+ C C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFF 148
Query: 2049 VKSENCIDINECDEDPNICLFGS------CTNTP-GGFQCLCPPGFVLSDNGRRCFDTRQ 2101
+ I+ +E N C+ C TP GG C C PGF L+ N + C T
Sbjct: 149 LSDNQHTCIHRSNEGMN-CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT-- 205
Query: 2102 SFCFTNFENGKCSVPKAFNTTKAKCCC-SKMPGEGWGDPC-ELCP----------KDDEV 2149
N+ NG C T C C K G C E C KD
Sbjct: 206 ----CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTAT 261
Query: 2150 AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGV 2209
+ CP G P T +D+NECL + G C + C NT GSF C C GY L
Sbjct: 262 GVRCSCPVGFTLQPD-GKTCKDINECLVNNGGCDHF-CRNTVGSFECGCRKGYKLLTDER 319
Query: 2210 RCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCM 2269
C D DECS C + C N GSF+C C+ G+ +C D++EC+ + C C+
Sbjct: 320 TCQDIDECSFERTCDH-ICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCV 378
Query: 2270 NTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI--CPPGM 2327
NT GSYEC CP G L + K C + +C + C G C CP
Sbjct: 379 NTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHT 438
Query: 2328 ARRPDGE 2334
PD E
Sbjct: 439 LFVPDSE 445
Score = 203 bits (517), Expect = 2e-51
Identities = 132/418 (31%), Positives = 190/418 (45%), Gaps = 45/418 (10%)
Query: 2253 DINECAQNPLLCAFR--CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGM 2310
D++EC++ C C NT SY+C C GY + + K C+D+DEC +D + G
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECE---NDYYNGGC 87
Query: 2311 M--CKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEG 2368
+ C N+ G + C C G DG C+D +EC+ G C+ CVN +GSY C+C+ G
Sbjct: 88 VHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 2369 F----------QSSSSGTECLDNRQGLCFAEVLQT-----ICQMASSSRNLVTKSEC--- 2410
F S+ G C++ G C +T C + +C
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNKDHG-CAHICRETPKGGVACDCRPGFDLAQNQKDCTLT 205
Query: 2411 CCDGGRGWGHQCELCPL-PGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
C G G H CE P ++K H G T I+ C V C C +T
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC----IETCAVNNGGCDR-TCKDTA 260
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKT 2529
RC C VG+T G +C D++EC + C++ C+NT GS++C C +GY L D +T
Sbjct: 261 TGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERT 320
Query: 2530 CKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA-CIDNNECGSQPSLCGAKGIC 2588
C+D+DEC + + C +C+N+ G F C C G+ + T C D +EC C C
Sbjct: 321 CQDIDEC-SFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG--C 377
Query: 2589 QNTPGSFSCECQRGFSLDATGLNCEDVDEC----DGNHRCQHGCQNILGGYRC--GCP 2640
NT GS+ C C G L G +C + +C + R Q C G C CP
Sbjct: 378 VNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCP 435
Score = 196 bits (498), Expect = 3e-49
Identities = 118/342 (34%), Positives = 156/342 (45%), Gaps = 57/342 (16%)
Query: 2433 YKKICPHGPGYTTDGR---DIDECKVMPNLCTNG----QCINTMGSFRCFCKVGYTTDIS 2485
YK +C PGY +G+ DIDEC+ N NG +CIN G++RC C G+
Sbjct: 57 YKCLCK--PGYKGEGKQCEDIDECE---NDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 2486 GTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTC----KDLDECQTKQH 2541
G +C+D+DEC + C IC N GSY+C C G+ L ++ TC + C K H
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 2542 NCQFLCVNT-LGGFTCKCPPGFT-------------------QHHTACIDNNE-CG---- 2576
C +C T GG C C PGF QH D CG
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQK 231
Query: 2577 ----SQPSLC---------GAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNH 2622
S C G C++T C C GF+L G C+D++EC N
Sbjct: 232 YALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 2623 RCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPS 2682
C H C+N +G + CGC +GY C D +ECS C C N+ GS++C C
Sbjct: 292 GCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHI-CINSPGSFQCLCHR 350
Query: 2683 GFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPG 2724
G+ ++ C DV+ECS S C+ GC NT+G Y C CPPG
Sbjct: 351 GYIL-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 192 bits (489), Expect = 3e-48
Identities = 103/288 (35%), Positives = 145/288 (50%), Gaps = 19/288 (6%)
Query: 2449 DIDECKVMPNLC-TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQS--PKPCNYI 2505
D+DEC + C + C NT S++C CK GY + G C D+DEC C +
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDECENDYYNGGCVHE 90
Query: 2506 CKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--- 2562
C N G+Y+C+C G++L DG C D+DECQ CQ +CVN +G + C+C GF
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 2563 TQHHTACIDNNE---CGSQPSLCGAKGICQNTP-GSFSCECQRGFSLDATGLNCEDVDEC 2618
HT +NE C ++ G IC+ TP G +C+C+ GF L +C C
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDH--GCAHICRETPKGGVACDCRPGFDLAQNQKDC--TLTC 206
Query: 2619 D-GNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYK 2677
+ GN CQH C++ G CGC Q Y H C++ C+ N +C +T +
Sbjct: 207 NYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE--TCAVNNGGCDRTCKDTATGVR 264
Query: 2678 CACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
C+CP GF+ C D+NEC + C++ C NT G + CGC GY
Sbjct: 265 CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGY 312
Score = 191 bits (485), Expect = 9e-48
Identities = 128/405 (31%), Positives = 179/405 (44%), Gaps = 53/405 (13%)
Query: 1361 GTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCS 1420
G G DVDEC G +C + A C N P S+KC C+ G+ G G +C D+DEC N +
Sbjct: 27 GLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGG 86
Query: 1421 INAQCVNTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEM 1478
+C+N PG+YRC C +GF DG C DVDEC +N C+ C+N G+Y C+C
Sbjct: 87 CVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHS 145
Query: 1479 GFTPASDSRSC----QDIDECSFQNICVFGTCNNLP-GMFHCICDDGYELDRTGGNCTDI 1533
GF + + +C + C ++ C P G C C G++L + +CT
Sbjct: 146 GFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT-- 203
Query: 1534 DECADPINCVNG------LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRG 1587
+ C G C +T C C + L+ G C++ N G
Sbjct: 204 ------LTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVN-------NG 250
Query: 1588 DGSLSC-NTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN--------------STEYYTL 1632
+C +T GV C C +G +TC +N +T
Sbjct: 251 GCDRTCKDTATGV-----RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFE 305
Query: 1633 CPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICED 1692
C +G++ +DIDEC C CIN+ GSFQC C +GY L T C D
Sbjct: 306 CGCRKGYKLLTDERTCQDIDEC-SFERTCD-HICINSPGSFQCLCHRGYILYGTTH-CGD 362
Query: 1693 IDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRK 1737
+DEC G C G C NT G+Y C+CPP G +C++ K
Sbjct: 363 VDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGK 406
Score = 190 bits (483), Expect = 2e-47
Identities = 134/393 (34%), Positives = 181/393 (46%), Gaps = 49/393 (12%)
Query: 534 IDVDECT--SNPC-TNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG- 589
+DVDEC+ ++ C + C NTP SY C C G++ + C DIDEC + NG
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYY---NGG 86
Query: 590 ---RCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
C+N G+++C C GF L DG NC+D DEC N +C+N GS++C C G
Sbjct: 87 CVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSG 146
Query: 647 FVLAPNGRYCTDVDECQTPGICMN-----GHCINS--EGSFRCDCPPGLAVGMDGRVCVD 699
F L+ N C + CMN H +G CDC PG + + + C
Sbjct: 147 FFLSDNQHTC--IHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT- 203
Query: 700 THMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPD--YGFGEPC-QPCPAKNSA------ 750
TC G G C T C C + G C + C N
Sbjct: 204 ----LTCNYG--NGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCK 257
Query: 751 -EFHGL-CSSGVGITV--DG---RDINECALDPDICANGICENLRGSYRCNCNSGYEPDA 803
G+ CS VG T+ DG +DINEC ++ C + C N GS+ C C GY+
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFCRNTVGSFECGCRKGYKLLT 316
Query: 804 SGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE-SNPCV 862
R C DIDEC R CD+ +C N+PGS+ C C GY+ T C D++EC SN
Sbjct: 317 DERTCQDIDECSFER-TCDH-ICINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSC 373
Query: 863 NGACRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
+ C N GS+ C C PG +L G C+++ K
Sbjct: 374 DQGCVNTKGSYECVCPPGRRLHWNGKDCVETGK 406
Score = 189 bits (480), Expect = 3e-47
Identities = 133/438 (30%), Positives = 187/438 (42%), Gaps = 80/438 (18%)
Query: 574 IDIDECIQNGVLCK-NGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMC 632
+D+DEC + C + C NT S++C+C G++ +GK C D DEC N NG C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECE--NDYYNGGC 87
Query: 633 INE----DGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGL 688
++E G+++C C GF+LA +G C DVDECQ C+N+ GS+ C C G
Sbjct: 88 VHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Query: 689 AVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKN 748
+ + C+ + C N D+G C+ P
Sbjct: 148 FLSDNQHTCIHR-----------------------SNEGMNCMNKDHGCAHICRETPKGG 184
Query: 749 SAEFHGLCSSGVGITVDGRDIN-ECALDPDICANGICENLRGSYRCNCNSGYEPDASGRN 807
A C G + + +D C C + CE+ C C+ Y + GR
Sbjct: 185 VACD---CRPGFDLAQNQKDCTLTCNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRT 240
Query: 808 CIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC- 866
CI+ C VN CD C++T C+CP G+ + + +TC+DINEC N NG C
Sbjct: 241 CIET--CAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVN---NGGCD 294
Query: 867 ---RNNLGSFNCECSPGSKLSSTGLICID----SLKGTCWLNIQDSRCEVNINGATLKSE 919
RN +GSF C C G KL + C D S + TC D C +N G+
Sbjct: 295 HFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTC-----DHIC-INSPGS----- 343
Query: 920 CCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFH 979
C RG C DV+EC + G C G CVN+KGS+
Sbjct: 344 -----------------FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYE 385
Query: 980 CECPEGLTLDGTGRVCLD 997
C CP G L G+ C++
Sbjct: 386 CVCPPGRRLHWNGKDCVE 403
Score = 187 bits (476), Expect = 1e-46
Identities = 127/409 (31%), Positives = 187/409 (45%), Gaps = 82/409 (20%)
Query: 1016 VPGKFRMDACC-----CAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPF 1070
+PG +D C C + A C+ PK Y+ LC G+ G
Sbjct: 28 LPGSVDVDECSEGTDDCHIDAI----CQNTPK----SYKCLCK--PGYKGEGKQC----- 72
Query: 1071 YKDINECKA--FPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS 1128
+DI+EC+ + G C + +C N G+++C C GF L + NC D+DEC+ + C
Sbjct: 73 -EDIDECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ 130
Query: 1129 GICVNTPGSFECECFEGYESGFMMMKN-------------CMDIDE-----CERNP---- 1166
ICVN GS+EC+C SGF + N CM+ D C P
Sbjct: 131 -ICVNAMGSYECQC----HSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGV 185
Query: 1167 ------------------LLCRGG------TCVNTEGSFQCDCPLGHELSPSREDCVDIN 1202
L C G +C +T+ C C + L C++
Sbjct: 186 ACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIET- 244
Query: 1203 ECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEG 1262
C++++ C + C + +CSC G+ PD + C DI+EC++ NGGCD C N+ G
Sbjct: 245 -CAVNNGGC-DRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVG 302
Query: 1263 SYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT 1322
S+EC C +GY L+ D R+C DIDEC + CD C N PG ++CLC+ G++
Sbjct: 303 SFECGCRKGYKLLTDERTCQDIDEC-SFERTCD-HICINSPGSFQCLCHRGYIL-YGTTH 359
Query: 1323 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC 1371
C DV+EC +++ C G C NTKGS+ C C G + C + +C
Sbjct: 360 CGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
Score = 179 bits (455), Expect = 3e-44
Identities = 133/443 (30%), Positives = 194/443 (43%), Gaps = 66/443 (14%)
Query: 471 VGGAGVGAGGQGPIITGLTILNQTIDICKHHANLC-LNGRCIPTVSSYRCECNMGYKQDA 529
+G G AGG G + G + +D C + C ++ C T SY+C C GYK +
Sbjct: 16 LGTRGRLAGGSG--LPG----SVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEG 69
Query: 530 NGDCIDVDECTSNPCTNG---DCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC 586
C D+DEC ++ G +C+N PG+Y C C GF C+D+DEC N C
Sbjct: 70 K-QCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC 128
Query: 587 KNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINED---------- 636
+ CVN GS++C C++GF L+ + C+ +N +N C+N+D
Sbjct: 129 QQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHR-----SNEGMN--CMNKDHGCAHICRET 180
Query: 637 --GSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDG 694
G C C+PGF LA N + CT G C + C +++ C C A+ DG
Sbjct: 181 PKGGVACDCRPGFDLAQNQKDCTLTCNYGNGG-CQHS-CEDTDTGPTCGCHQKYALHSDG 238
Query: 695 RVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCA-----NPDYGFGEPCQPCPAKNS 749
R C++T C + G C R T C C PD + C N
Sbjct: 239 RTCIET-----C--AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 750 A----------EFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCN 796
F C G + D R DI+EC+ + + IC N GS++C C+
Sbjct: 292 GCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERT--CDHICINSPGSFQCLCH 349
Query: 797 SGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC 856
GY + +C D+DEC ++ CD G C NT GSY C CPPG + C + +C
Sbjct: 350 RGYILYGT-THCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
Query: 857 ----ESNPCVNGACRNNLGSFNC 875
+++P +C G +C
Sbjct: 408 LSRAKTSPRAQLSCSKAGGVESC 430
Score = 178 bits (452), Expect = 6e-44
Identities = 122/395 (30%), Positives = 174/395 (44%), Gaps = 40/395 (10%)
Query: 1650 DIDECQELPGLCQ-GGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFA--HPGVCGPG 1706
D+DEC E C C NT S++C C GY + + CEDIDEC + G C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGC-VH 89
Query: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMRK---------SFCYRSYNGTTCENELPFNV 1757
C N GNY C C +M + GHNC+D+ + C + C+ F +
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFL 149
Query: 1758 TKRMCCCTYNVGKAWN---------KPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD 1808
+ C + + N C P G A C PGF D+ +
Sbjct: 150 SDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVA-----CDCRPGF--DLAQNQKDC 202
Query: 1809 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
C G C + C + C C ++ + C I+ C+ + C R C
Sbjct: 203 TLTCNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDRT--CK 257
Query: 1869 NSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQ 1927
++ RC C GF L P+G C D NECL C H C + GS++C C G+K
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSFECGCRKGYKLLT 316
Query: 1928 DQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
D+ C D+DEC + C N+ GS+ CLC+ G+ L C D+DECS G C
Sbjct: 317 DERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGS-CDQ 375
Query: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVA 2022
G C N GS++C+C G L +GK+C++T +C++
Sbjct: 376 G-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLS 409
Score = 170 bits (431), Expect = 2e-41
Identities = 128/443 (28%), Positives = 169/443 (38%), Gaps = 92/443 (20%)
Query: 2335 GCVDENECRTKPGICE-NGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
G VD +EC C + C N SY+C C G++ E +D
Sbjct: 30 GSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDID------------- 76
Query: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DI 2450
EC D G G E +PG Y+ C G DG D+
Sbjct: 77 ---------------ECENDYYNG-GCVHECINIPGN--YRCTCFDGFMLAHDGHNCLDV 118
Query: 2451 DECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDIS----------GTSCIDLDE-----C 2495
DEC+ C C+N MGS+ C C G+ + G +C++ D C
Sbjct: 119 DECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHIC 177
Query: 2496 SQSPK----------------------PCNY-------ICKNTEGSYQCSCPRGYVLQED 2526
++PK CNY C++T+ C C + Y L D
Sbjct: 178 RETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSD 237
Query: 2527 GKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA--CIDNNECGSQPSLCGA 2584
G+TC ++ C C C +T G C CP GFT C D NEC G
Sbjct: 238 GRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG--GC 293
Query: 2585 KGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYI 2644
C+NT GSF C C++G+ L C+D+DEC C H C N G ++C C +GYI
Sbjct: 294 DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Query: 2645 QHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSS--- 2701
Y C D +ECS N C NT GSY+C CP G C + +C S
Sbjct: 354 L-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAK 412
Query: 2702 SKNPCNYGCSNTEGGYLC--GCP 2722
+ CS G C CP
Sbjct: 413 TSPRAQLSCSKAGGVESCFLSCP 435
Score = 142 bits (359), Expect = 4e-33
Identities = 141/498 (28%), Positives = 190/498 (38%), Gaps = 118/498 (23%)
Query: 852 DINECE--SNPC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCE 908
D++EC ++ C ++ C+N S+ C C PG K G C D CE
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDI-----------DECE 79
Query: 909 VNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPN 968
+ EC G RC T + G C DV+EC+ G C
Sbjct: 80 NDYYNGGCVHECINIPGNY------RC---TCFDGFMLAHDGHNCLDVDECQDNNGGCQQ 130
Query: 969 GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH-----PVPGKFRMD 1023
CVN+ GS+ C+C G L C+ E + C H P G
Sbjct: 131 -ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGV---- 185
Query: 1024 ACCCAVGAAWGTECEEC---------------------PKPGTKEYETL------CPRGA 1056
AC C G ++C P G + L C
Sbjct: 186 ACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETC 245
Query: 1057 GFANRG------DVLTG--------------RPFYKDINECKAFPGMCTYGKCRNTIGSF 1096
N G D TG KDINEC G C + CRNT+GSF
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH-FCRNTVGSF 304
Query: 1097 KCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNC 1156
+C C G+ L +ER C DIDEC S + IC+N+PGSF+C C GY +C
Sbjct: 305 ECGCRKGYKLLTDERTCQDIDEC--SFERTCDHICINSPGSFQCLCHRGYI--LYGTTHC 360
Query: 1157 MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 1216
D+DEC + C G CVNT+GS++C CP G L + +DCV+ GKC
Sbjct: 361 GDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVE------------TGKC 407
Query: 1217 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCS----EGY 1272
++ T +P Q + + G ++ C + +SE SY SC +G
Sbjct: 408 LSRAKT-----SPRAQLSCSKAG--GVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGK 460
Query: 1273 ALMPD-------GRSCAD 1283
AL G SC+D
Sbjct: 461 ALQKRNGTSSGLGPSCSD 478
Score = 92.0 bits (227), Expect = 7e-18
Identities = 97/361 (26%), Positives = 133/361 (36%), Gaps = 71/361 (19%)
Query: 88 VCGSRFHSYCC---PGWKTLPGGNQCI-VPICRNSCGDGFCSRPNM-------CTCSSGQ 136
+C + SY C PG+K G QC + C N +G C + CTC G
Sbjct: 49 ICQNTPKSYKCLCKPGYKG--EGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGF 106
Query: 137 ISSTCGSKSIQQCSVRCMNGGT---CADD----HCQCQKGYIGTYCGQPVCENGCQNGGR 189
+ + G + + NGG C + CQC G+ + Q C + G
Sbjct: 107 MLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD-NQHTCIHRSNEGMN 165
Query: 190 CIGPNR---------------CACVYGFTGPQCERD------YRTGPCFTQVNNQMCQGQ 228
C+ + C C GF Q ++D Y G C C+
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGC-----QHSCEDT 220
Query: 229 LTGIVC-------------TKTLCCATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGAC 274
TG C T CA C+ + C GF C
Sbjct: 221 DTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTC 280
Query: 275 QDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
+D++EC G C C NTVGSFEC C G+K + C+DIDECS C+ C
Sbjct: 281 KDINECLVNNGGCDHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCD-HIC 337
Query: 335 SNTVGSYFCVCPRGYVT-STDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
N+ GS+ C+C RGY+ T +D+ + NG C Q +C C PG
Sbjct: 338 INSPGSFQCLCHRGYILYGTTHCGDVDE------CSMSNGSCDQGCVNTKGSYECVCPPG 391
Query: 394 R 394
R
Sbjct: 392 R 392
Score = 89.7 bits (221), Expect = 4e-17
Identities = 82/274 (29%), Positives = 111/274 (40%), Gaps = 55/274 (20%)
Query: 97 CCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNG 156
C PG+ C + + G+G C +C TCG Q +G
Sbjct: 189 CRPGFDLAQNQKDCTLTC---NYGNGGCQH----SCEDTDTGPTCGC---HQKYALHSDG 238
Query: 157 GTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPC 216
TC + C G C+ C++ + RC+C GFT + D +T
Sbjct: 239 RTCIET-CAVNNGG---------CDRTCKDTATGV---RCSCPVGFT---LQPDGKTCKD 282
Query: 217 FTQ--VNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGAC 274
+ VNN C C T+G C CR+G+ C
Sbjct: 283 INECLVNNGGCDH----------FCRNTVG---SFECG--------CRKGYKLLTDERTC 321
Query: 275 QDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
QD+DEC + C CIN+ GSF+C C G+ TT C D+DECS+ G C+ G C
Sbjct: 322 QDIDEC-SFERTCDH-ICINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQG-C 377
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFS 368
NT GSY CVCP G +G C++ TG C S
Sbjct: 378 VNTKGSYECVCPPGRRLHWNGKDCVE--TGKCLS 409
Score = 78.6 bits (192), Expect = 9e-14
Identities = 48/135 (35%), Positives = 59/135 (43%), Gaps = 10/135 (7%)
Query: 2614 DVDEC-DGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSA--S 2668
DVDEC +G C CQN Y+C C GY + QC D +EC N G
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHE 90
Query: 2669 CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRV 2728
C N G+Y+C C GF C DV+EC + C C N G Y C C G++
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 2729 GQGH-CV--SGMGFN 2740
H C+ S G N
Sbjct: 151 DNQHTCIHRSNEGMN 165
Score = 35.0 bits (79), Expect = 1.1
Identities = 47/198 (23%), Positives = 69/198 (34%), Gaps = 39/198 (19%)
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCI-CPPGYEVKSENCIDINECDEDPNICLFGSCTN 2074
+ +CV SC PGT Q++EG C CP + +++EC G C
Sbjct: 642 ELGQCV----SCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECG--------GQC-- 687
Query: 2075 TPGGFQC-------LCPPGFVLSDNGRR-CFDTRQSFC-----FTNFENGK----CSVPK 2117
+PG F CP G + GR CF T+F++ + CS
Sbjct: 688 SPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGH 747
Query: 2118 AFNTTKAKCC---CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNE 2174
+NTT +C E + C CP + F H D
Sbjct: 748 HYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTG 807
Query: 2175 CLESPG----ICSNGQCI 2188
+ESP +N +C+
Sbjct: 808 YIESPNYPGDYPANAECV 825
Score = 33.9 bits (76), Expect = 2.4
Identities = 33/124 (26%), Positives = 43/124 (34%), Gaps = 32/124 (25%)
Query: 250 PCEMCPA---QPQPCRRGFIPN-----IRTGACQDVDECQAIPGICQGGNCINTVGSFEC 301
PC+ CP QP+P R G P + +C+A C G+ NT
Sbjct: 699 PCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVH-CSPGHHYNTTTHRCI 757
Query: 302 RCPAGHKQSETTQKCEDIDECSIIPG-------------ICETGECSNTVGSYFCVCPRG 348
RCP G Q E Q + C PG C+ C +G Y G
Sbjct: 758 RCPVGTYQPEFGQ-----NHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDY-----TG 807
Query: 349 YVTS 352
Y+ S
Sbjct: 808 YIES 811
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 246 bits (628), Expect = 2e-64
Identities = 286/1141 (25%), Positives = 451/1141 (39%), Gaps = 228/1141 (19%)
Query: 1084 CTYGKCRNTIG-----------SFKCRCNSGFALDMEERNCTDI-DECRISPDLCGSGIC 1131
C++ C+N +++C C+ F +NC++I +C+ P +C G C
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFT----GKNCSEIIGQCQ--PHVCFHGNC 270
Query: 1132 VN-TPGSFECECFEGYESGF--MMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLG 1188
N T SF CEC E + F + K C+ + L + G C N+ ++ +CP G
Sbjct: 271 SNITSNSFICECDEQFSGPFCEVSAKPCVSL-------LFWKRGICPNSSSAYTYECPKG 323
Query: 1189 HELSPSREDCVDINECSLSDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECM 1247
S S+ D++E SL C+NG C+ + C C+P + + T +
Sbjct: 324 ---SSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFP 378
Query: 1248 IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQ-CTNIPGE 1305
+ N + C E Y CSC G+ ++C ID C+ C + C NI G
Sbjct: 379 LRN---NATCKKCEKDYPCSCISGFT----EKNCEKAIDHCKLLSINCLNEEWCFNIIGR 431
Query: 1306 YRCLCYDGFMAS--MDMKTCIDVNECDLNSNICMFGECENT-KGSFICHCQLGYSVKKGT 1362
++ +C G + +K +++ + G C++ F QLG++ +G
Sbjct: 432 FKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGE 491
Query: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC---REGW---IGNGIKCIDLDECS--- 1413
+D A NC A+ +N P SC EG NG C+ ++
Sbjct: 492 KCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYR 551
Query: 1414 ------------------NGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE 1455
+ ++C A C + RC+CS + G +VD C
Sbjct: 552 YLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGR-LCVVNVDYCLG 610
Query: 1456 NINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFH 1514
N ++ +G CL + ++ C C + C+ D ++C + T +L G F
Sbjct: 611 NHSISVHGLCLAL--SHNCNCSG--LQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFF 666
Query: 1515 CICDDGYELDRTGGNCT-DIDECADPINCVNGL-CVNTPGRYECNCPPDFQLNPTGVGCV 1572
C G++ G C DIDECA C NG C++ PG Y C C P F++ G C+
Sbjct: 667 RKCVPGFK----GTQCEIDIDECASH-PCKNGATCIDQPGNYFCQCVPPFKV-VDGFSCL 720
Query: 1573 DNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE---TCPPVNSTEY 1629
N G + C +I C L N CE TC ++ +
Sbjct: 721 CNP-----------GYVGIRCEQDIDD--------CIL-----NACEHNSTCKDLHLSYQ 756
Query: 1630 YTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQCECPQGYYLSEDTR 1688
EG ++ +EC+ P C+ + C + + S++CEC G+
Sbjct: 757 CVCLSDWEG------NFCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSGW---TGQN 805
Query: 1689 ICEDIDECFAHPGVCGPGTCYNTL--GNYTCICPPEYMQ--VNGGHNCMDMRKSFCYRSY 1744
E+I+EC + P + G G C+ + G + C+CPP Y + +N D+ + C
Sbjct: 806 CSEEINECDSDPCMNG-GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCR--- 861
Query: 1745 NGTTCENELPFNVTKRMCCCTYNVGKAWNKPCE---------PCPTPGTAD-----FKTI 1790
N +TC L + C C K CE C G + F+ I
Sbjct: 862 NNSTC---LALVDANQHCICREEFE---GKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCI 915
Query: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPGICAN-GVCINQIGSFRCECPTGFSYNDLLLVCE 1849
C PGF+ + ++I+EC P C N G C++ F C C + CE
Sbjct: 916 CR--PGFSGSLCE---IEINECSSEP--CKNNGTCVDLTNRFFCNCEPEYHGP----FCE 964
Query: 1850 -DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH-GL 1907
D+++C L + N C+ Y C CA G+ + ++ +ECL P C H G+
Sbjct: 965 LDVNKCKISPCLDEEN--CVYRTDGYNCLCAPGY--TGINCEINLDECLSEP--CLHDGV 1018
Query: 1908 CVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTH 1967
C+D Y C C +GF + +T + ++C +PC +G C + Y C C + T
Sbjct: 1019 CIDGINHYTCDCKSGFFGTHCET---NANDCLSNPCLHGRCTELINEYPCSC--DADGTS 1073
Query: 1968 NNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYE-------------------L 2007
+ I++C+S C N G C F C+C GY +
Sbjct: 1074 TQCKIKINDCTSI---PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVI 1130
Query: 2008 TPDGKNCID----TNECVALPG-------------SCSP----GTCQNLEGSFRCICPPG 2046
+G C+D T +C LPG S SP C++ + C C PG
Sbjct: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPG 1190
Query: 2047 YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD-TRQSFCF 2105
+ +C + EC PN C+ C G CLC PGF+ G C D R+ C
Sbjct: 1191 WS--GHHCENELECI--PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCL 1246
Query: 2106 T 2106
T
Sbjct: 1247 T 1247
Score = 226 bits (575), Expect = 3e-58
Identities = 291/1184 (24%), Positives = 445/1184 (37%), Gaps = 289/1184 (24%)
Query: 1331 LNSNICM-FGEC--ENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNI 1387
L+S C G+C E ++ CHCQ +S K C ++D C C + SC+N
Sbjct: 178 LSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKY----CQELDACSFKP--CKNNGSCINK 231
Query: 1388 -----PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVN-TPGSYRCACSEGFT 1441
+++C C + G I + +C H C + C N T S+ C C E F+
Sbjct: 232 RENWDEQAYECVCHPPFTGKNCSEI-IGQCQ--PHVC-FHGNCSNITSNSFICECDEQFS 287
Query: 1442 GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRS--------CQDID 1493
G C + ++ + G C N AY EC G + + CQ+
Sbjct: 288 GP--FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGT 345
Query: 1494 EC---------------------SFQNICVF------GTCNNLPGMFHCICDDGYELDRT 1526
+C S Q C TC + C C G+ T
Sbjct: 346 DCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF----T 401
Query: 1527 GGNCTD-IDECAD-PINCVNG-LCVNTPGRYECNCPPDFQLNPTGVGCVDNR---VGNCY 1580
NC ID C INC+N C N GR++ C P GC N + N Y
Sbjct: 402 EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP---------GCTKNPCWFLKNVY 452
Query: 1581 LKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTL-CPGGEGF 1639
L + + C C G + C+ P + L G EG
Sbjct: 453 L-------------------IHQHLCYC--GVTFHGICQDKGPAQFEYVWQLGFAGSEGE 491
Query: 1640 RPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC-FA 1698
+ CQG I+ + C + D ++ C F
Sbjct: 492 K--------------------CQG--VIDAYFFLAANCTEDATYVNDPE--DNNSSCWFP 527
Query: 1699 HPG---VCGPG-TCYNTLGN--YTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENE 1752
H G +C G +C + + Y +C + N D +++ C C++E
Sbjct: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE---AVCKDE 584
Query: 1753 LPFNVTKRMCCCTYN-VGKAWNKPCEPCPTPGTADFKTIC------GNIPGFTFDIHTGK 1805
+ + C C+ + +G+ + C + +C N G
Sbjct: 585 ----INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNIC 640
Query: 1806 AVDIDECKEIPGICANGVCINQI-GSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQR 1863
+D ++CK C NG + G F +C GF CE DIDEC++ + C+
Sbjct: 641 EIDTEDCKSAS--CKNGTTSTHLRGYFFRKCVPGFKGTQ----CEIDIDECAS--HPCKN 692
Query: 1864 NADCINSPGSYRCECAAGFKLSPNGACV------------DRNECLEIPNVCSH-GLCVD 1910
A CI+ PG+Y C+C FK+ +C+ D ++C I N C H C D
Sbjct: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC--ILNACEHNSTCKD 750
Query: 1911 LQGSYQCICHNGFKASQDQTMCMDVDECERHPC-GNGTCKNTVGSYNCLCYPGFELTHNN 1969
L SYQC+C + ++ + + + +EC+ +PC N TC + SY C C G+ T N
Sbjct: 751 LHLSYQCVCLSDWEGNFCE---QESNECKMNPCKNNSTCTDLYKSYRCECTSGW--TGQN 805
Query: 1970 DCLDIDECSSFFGQVCRNGRCFNEI---GSFKCL---------CNEGYELTP-------- 2009
+I+EC S C NG +E G F CL C++ Y L
Sbjct: 806 CSEEINECDS---DPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRN 862
Query: 2010 --------------------DGKNC-IDTNECVALPGSCSP-GTCQNLEGSFRCICPPGY 2047
+GKNC ID +C+ L SC G C+++ +FRCIC PG+
Sbjct: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL--SCQDYGDCEDMVNNFRCICRPGF 920
Query: 2048 EVKSENC-IDINECDEDPNICL-FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF 2105
C I+INEC +P C G+C + F C C P + FC
Sbjct: 921 --SGSLCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEPEY------------HGPFC- 963
Query: 2106 TNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSL 2165
+ KC + + C + G + LC G+ +
Sbjct: 964 -ELDVNKCKISPCLDEEN---CVYRTDG-----------------YNCLCAPGYTGI--- 999
Query: 2166 HDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGN 2225
+ +++ECL P + +G CI+ + C+C G + G C + NPC +
Sbjct: 1000 -NCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSG----FFGTHCETNANDCLSNPCLH 1053
Query: 2226 GTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIGYA 2284
G CT +I + C+C+ G C+ IN+C P + C + + C CP GY
Sbjct: 1054 GRCTELINEYPCSCD---ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYT 1110
Query: 2285 LREDQKMCKDLDECAEGLHD---CESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDEN 2340
+ K +D CAE + C + G+ TF C C PG + G+ C ++ N
Sbjct: 1111 GAYCE---KSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS----GQFCEININ 1163
Query: 2341 ECRTKPGICENGR-CVNIIGSYRCECNEGFQS--SSSGTECLDN 2381
EC + P C +G C + I Y C+C G+ + EC+ N
Sbjct: 1164 ECSSSP--CLHGADCEDHINGYVCKCQPGWSGHHCENELECIPN 1205
Score = 221 bits (562), Expect = 1e-56
Identities = 311/1248 (24%), Positives = 466/1248 (37%), Gaps = 259/1248 (20%)
Query: 1569 VGCVDNRVGNCYLKFGPRGDGSLSCNTE-IGVGVSRSSCCCSLGKAWGNPCETCPPVNST 1627
VGCV N L FG R G + N++ + VG + G + PC +N T
Sbjct: 112 VGCVQNTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPS---PCPLGLRLNVT 168
Query: 1628 EYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGS--FQCECPQGYYLS 1684
C E + C G G C++ S + C C +
Sbjct: 169 VKQQFCQ--------------ESLSS-----EFCSGHGKCLSEAWSKTYSCHCQPPF--- 206
Query: 1685 EDTRICEDIDECFAHPGVC-GPGTCYNTLGN-----YTCICPPEYMQVNGGHNCMDM--- 1735
+ C+++D C P C G+C N N Y C+C P + G NC ++
Sbjct: 207 -SGKYCQELDACSFKP--CKNNGSCINKRENWDEQAYECVCHPPFT----GKNCSEIIGQ 259
Query: 1736 -RKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKP-CEPCPTPGTADF---KTI 1790
+ C+ C N +T C + + ++ P CE P + + I
Sbjct: 260 CQPHVCFHG----NCSN-----ITSNSFICECD--EQFSGPFCEVSAKPCVSLLFWKRGI 308
Query: 1791 CGNIPG-FTFDIHTGKA-----VDIDECKEIPGICANGV-CINQIGSFRCECPTGFSYND 1843
C N +T++ G + D+ E +P C NG CI C C F+ D
Sbjct: 309 CPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFT--D 364
Query: 1844 LLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC 1903
LL C+ I L + NA C Y C C +GF +D + L I N
Sbjct: 365 LL--CKSIQTSCESFPL-RNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSI-NCL 420
Query: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGF 1963
+ C ++ G ++ +C G C ++PC KN + LCY G
Sbjct: 421 NEEWCFNIIGRFKYVCIPG---------------CTKNPCW--FLKNVYLIHQHLCYCG- 462
Query: 1964 ELTHNNDCLDIDECSSFFGQVCRNG-------RCFNEIGSFKCL---CNEGYELTPDGKN 2013
+T + C D F V + G +C I ++ L C E D +
Sbjct: 463 -VTFHGICQDKGPAQ--FEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPE- 518
Query: 2014 CIDTNECVALPGS-----CSPG-TCQNLEGS--FRCICPPGYEVKSENCIDINECDEDPN 2065
D N P C+ G +C + E S +R +C + + N N D+ N
Sbjct: 519 --DNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLC---FLRWAGNMYLENTTDDQEN 573
Query: 2066 ICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA 2124
C + C + +C C ++ GR C +C N SV
Sbjct: 574 ECQHEAVCKDEINRPRCSCSLSYI----GRLCV-VNVDYCLGNHS---ISVHGLCLALSH 625
Query: 2125 KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGT-----------VPSLHDTR--ED 2171
C CS + +C D E C G + VP T+ D
Sbjct: 626 NCNCSGLQRY----ERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEID 681
Query: 2172 VNECLESPGICSNGQ-CINTDGSFRCECPMGY----------NLDYTGVRCV-DTDECSI 2219
++EC P C NG CI+ G++ C+C + N Y G+RC D D+C +
Sbjct: 682 IDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
Query: 2220 GNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECT 2278
N TC ++ S++C C +E CE + NEC NP C + + SY C
Sbjct: 740 NACEHNSTCKDLHLSYQCVCLSDWEGN---FCEQESNECKMNPCKNNSTCTDLYKSYRCE 796
Query: 2279 CPIGYALREDQKMCKDLDECAEGLHDCES----RGMMC--KNLIGTFMCICPPGMARRPD 2332
C G+ + C+E +++C+S G +C + G F+C+CPP
Sbjct: 797 CTSGWTGQN----------CSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYT---- 842
Query: 2333 GEGCVDE-NECRTKPGICENGR-CVNII-GSYRCECNEGFQSSSSGTECLDNRQGLCFAE 2389
G+ C N C C N C+ ++ + C C E F+ + + D
Sbjct: 843 GQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD--------- 893
Query: 2390 VLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRD 2449
L CQ ++V C C G G CE+ +
Sbjct: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFS-GSLCEI------------------------E 928
Query: 2450 IDECKVMPNLC-TNGQCINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICK 2507
I+EC P C NG C++ F C C+ Y G C +D+++C SP C
Sbjct: 929 INECSSEP--CKNNGTCVDLTNRFFCNCEPEY----HGPFCELDVNKCKISPCLDEENCV 982
Query: 2508 NTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHH 2566
Y C C GY G C+ +LDEC ++ +C++ + +TC C GF H
Sbjct: 983 YRTDGYNCLCAPGYT----GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTH 1038
Query: 2567 TACIDN-NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDGNHRC 2624
C N N+C S P L G C + C C D T C+ +++C
Sbjct: 1039 --CETNANDCLSNPCLHGR---CTELINEYPCSCDA----DGTSTQCKIKINDCTSIPCM 1089
Query: 2625 QHG-CQNILGGYRCGCPQGYIQHYQWNQCVD---ENECSNPNACGSASCYNTLG-SYKCA 2679
G CQ G+ C CP+GY Y + +D E E ++ C + G ++ C
Sbjct: 1090 NEGFCQKSAHGFTCICPRGYTGAY-CEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCR 1148
Query: 2680 CPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGY 2725
C GFS QF ++NECSSS PC +G C + GY+C C PG+
Sbjct: 1149 CLPGFS-GQFCEI--NINECSSS--PCLHGADCEDHINGYVCKCQPGW 1191
Score = 218 bits (555), Expect = 7e-56
Identities = 269/1082 (24%), Positives = 409/1082 (37%), Gaps = 208/1082 (19%)
Query: 602 CNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS--FKCICKPGFVLAPNGRYCTDV 659
C G L K + ++ +G C++E S + C C+P F +G+YC ++
Sbjct: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGKYCQEL 214
Query: 660 DECQTPGICMNGHCIN-----SEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGV 714
D C NG CIN E ++ C C P G+ C S G + V
Sbjct: 215 DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFT----GKNC------SEIIGQCQPHV 264
Query: 715 CVRPFPGAVTKSECCCANPDYGFGEPCQ----PCPA----------KNSAEFHGLCSSGV 760
C +T + C + G C+ PC + +S+ + C G
Sbjct: 265 CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGS 324
Query: 761 GITVDGRDINECALDPDICANGI-CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRL 819
D++E +L P C NG C + C C+ P + C I +
Sbjct: 325 SSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICS----PIFTDLLCKSIQTSCESFP 378
Query: 820 LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNGA-CRNNLGSFNCE 876
L +N C+ Y C+C G+ TE + I+ C+ S C+N C N +G F
Sbjct: 379 LRNNATCKKCEKDYPCSCISGF---TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYV 435
Query: 877 CSPGSKLSSTGLICIDSLKGTCWL--NIQDSRCEVNINGATLKSECCATLGAAWGSPCER 934
C PG K CW N+ + G T C G A
Sbjct: 436 CIPG------------CTKNPCWFLKNVYLIHQHLCYCGVTFHG-ICQDKGPA------- 475
Query: 935 CELDTACPRGLARIKGVTCEDVNECEVF--PGVCPNGRCVNSKGSFHCEC---PEGL-TL 988
+ + G A +G C+ V + F + VN + C EG +
Sbjct: 476 -QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEI 534
Query: 989 DGTGRVCLDIRMEQ-----CYLKW------------DEDECIHPVPGKFRMD--ACCCA- 1028
G CL Q C+L+W E+EC H K ++ C C+
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
Query: 1029 --VGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTY 1086
+G + C + LC + N +G Y + N C+ C
Sbjct: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCN----CSGLQRY-ERNICEIDTEDCKS 649
Query: 1087 GKCRNTI------GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFE 1139
C+N G F +C GF E DIDEC P C +G C++ PG++
Sbjct: 650 ASCKNGTTSTHLRGYFFRKCVPGFKGTQCE---IDIDECASHP--CKNGATCIDQPGNYF 704
Query: 1140 CECFEGYE----------SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGH 1189
C+C ++ G++ ++ DID+C N TC + S+QC C
Sbjct: 705 CQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE-HNSTCKDLHLSYQCVCLSDW 763
Query: 1190 ELSPSREDCVDINECSLSDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI 1248
E + ++ NEC + N C+N C ++ +Y+C C G+ + + D
Sbjct: 764 EGNFCEQES---NECKM--NPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
Query: 1249 MNGGCDTQCTNSEGSYECSCSEGY--------------------------ALMPDGRSCA 1282
MNGG + T G + C C Y AL+ + C
Sbjct: 819 MNGGLCHEST-IPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCI 877
Query: 1283 DIDE-----CENNPDIC------DGGQCTNIPGEYRCLCYDGFMASMDMKTC-IDVNECD 1330
+E CE + C D G C ++ +RC+C GF S+ C I++NEC
Sbjct: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSL----CEIEINEC- 932
Query: 1331 LNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
+S C G C + F C+C+ Y G DV++C+I C +C+
Sbjct: 933 -SSEPCKNNGTCVDLTNRFFCNCEPEY---HGPFCELDVNKCKISP--CLDEENCVYRTD 986
Query: 1390 SFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS 1448
+ C C G+ GI C I+LDEC + C + C++ Y C C GF G +
Sbjct: 987 GYNCLCAPGY--TGINCEINLDECL--SEPCLHDGVCIDGINHYTCDCKSGFFGTHCE-T 1041
Query: 1449 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCN 1507
+ ++C N C +G+C + Y C C+ T S C+ I++C+ G C
Sbjct: 1042 NANDCLS--NPCLHGRCTELINEYPCSCDADGT----STQCKIKINDCTSIPCMNEGFCQ 1095
Query: 1508 NLPGMFHCICDDGYELDRTGGNC-TDIDECADP----INCVN-GLCVNTPGR-YECNCPP 1560
F CIC GY TG C ID CA+P + C+N G+CV+ PG ++C C P
Sbjct: 1096 KSAHGFTCICPRGY----TGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLP 1151
Query: 1561 DF 1562
F
Sbjct: 1152 GF 1153
Score = 209 bits (533), Expect = 2e-53
Identities = 295/1204 (24%), Positives = 463/1204 (38%), Gaps = 222/1204 (18%)
Query: 476 VGAGGQGPIITGLTILNQTI--DICKHH--ANLCL-NGRCIPTVSS--YRCECNMGYKQD 528
V A G P GL LN T+ C+ + C +G+C+ S Y C C +
Sbjct: 151 VMASGPSPCPLGLR-LNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF--- 206
Query: 529 ANGDCIDVDECTSNPC-TNGDCVN-----TPGSYYCKCHAGFQRTPTKQACIDIDECIQN 582
+ C ++D C+ PC NG C+N +Y C CH F T + C +I Q
Sbjct: 207 SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQP 262
Query: 583 GVLCKNGRCVN-TDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFK 640
V C +G C N T SF C C+ F G C V C + G+C N ++
Sbjct: 263 HV-CFHGNCSNITSNSFICECDEQF----SGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317
Query: 641 CICKPG------------FVLAP--NGRYCTDVD---------------------ECQTP 665
C G F L P NG C + C++
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESF 377
Query: 666 GICMNGHCINSEGSFRCDCPPGL-------AVGMDGRVCVDTHMRSTCYG--GIKKGVCV 716
+ N C E + C C G A+ + ++ C+ G K VC+
Sbjct: 378 PLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCI 437
Query: 717 RPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC-SSGVGITVDGRDINECALD 775
PG TK+ C Y + C FHG+C G + +
Sbjct: 438 ---PGC-TKNPCWFLKNVYLIHQHLCYC----GVTFHGICQDKGPAQFEYVWQLGFAGSE 489
Query: 776 PDICANGICENLRGSYRCNCNSGY--EPDASGRNCIDIDECLVNRLLCDNGL-CRNTPGS 832
+ C I + C ++ Y +P+ + +C E + +C NG C + S
Sbjct: 490 GEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHE--GTKEICANGCSCLSEEDS 547
Query: 833 ----YSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGL 888
Y C E T + NEC+ C++ + C CS LS G
Sbjct: 548 QEYRYLCFLRWAGNMYLENTTDDQENECQH----EAVCKDEINRPRCSCS----LSYIGR 599
Query: 889 ICI-----------DSLKGTCWLNIQDSRC----EVNINGATLKSECCATLGAAWGSPCE 933
+C+ S+ G C + C N + +E C + G+
Sbjct: 600 LCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTST 659
Query: 934 --RCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHCEC-PEGLTL 988
R C G KG CE D++EC P C NG C++ G++ C+C P +
Sbjct: 660 HLRGYFFRKCVPG---FKGTQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVV 714
Query: 989 DGTGRVC----LDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPG 1044
DG +C + IR EQ D D+CI ++AC E K
Sbjct: 715 DGFSCLCNPGYVGIRCEQ-----DIDDCI--------LNAC----------EHNSTCKDL 751
Query: 1045 TKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGF 1104
Y+ +C G ++ NECK P C + S++C C SG+
Sbjct: 752 HLSYQCVCLSD---------WEGNFCEQESNECKMNP-CKNNSTCTDLYKSYRCECTSGW 801
Query: 1105 ALDMEERNCT-DIDECRISPDLCGSGICVNT--PGSFECECFEGYESGFMMMKNCMDIDE 1161
+NC+ +I+EC P + G G+C + PG F C C Y F + ++ +
Sbjct: 802 T----GQNCSEEINECDSDPCMNG-GLCHESTIPGQFVCLCPPLYTGQFCHQR--YNLCD 854
Query: 1162 CERNPLLCR-GGTCVN-TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCVN 1218
NP CR TC+ + + C C E + +D+ +C C++ G C +
Sbjct: 855 LLHNP--CRNNSTCLALVDANQHCIC---REEFEGKNCEIDVKDCLFLS--CQDYGDCED 907
Query: 1219 MIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 1278
M+ ++C C PG+ + +I+EC + C + + C+C Y G
Sbjct: 908 MVNNFRCICRPGFSGSLCE---IEINECSSEPCKNNGTCVDLTNRFFCNCEPEY----HG 960
Query: 1279 RSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM 1337
C D+++C+ +P + D C Y CLC G+ + I+++EC L+
Sbjct: 961 PFCELDVNKCKISPCL-DEENCVYRTDGYNCLCAPGYTG---INCEINLDEC-LSEPCLH 1015
Query: 1338 FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCRE 1397
G C + + C C+ G+ GT T+ ++C N +H C + + CSC
Sbjct: 1016 DGVCIDGINHYTCDCKSGFF---GTHCETNANDC---LSNPCLHGRCTELINEYPCSCDA 1069
Query: 1398 GWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE- 1455
G +C I +++C+ + C C + + C C G+TG + +D CAE
Sbjct: 1070 D--GTSTQCKIKINDCT--SIPCMNEGFCQKSAHGFTCICPRGYTG-AYCEKSIDNCAEP 1124
Query: 1456 --NINLCENGQ-CLNVPG-AYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGT-CNNL 1509
N +C NG C++ PG + C C GF+ + C+ +I+ECS + C+ G C +
Sbjct: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFS----GQFCEININECS-SSPCLHGADCEDH 1179
Query: 1510 PGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGV 1569
+ C C G+ +G +C + EC P +CV+ LC+ C C P F G+
Sbjct: 1180 INGYVCKCQPGW----SGHHCENELECI-PNSCVHELCMENEPGSTCLCTPGFMTCSIGL 1234
Query: 1570 GCVD 1573
C D
Sbjct: 1235 LCGD 1238
Score = 190 bits (483), Expect = 2e-47
Identities = 283/1079 (26%), Positives = 413/1079 (38%), Gaps = 208/1079 (19%)
Query: 1649 EDIDECQELPGLCQGGNCIN-TFGSFQCECPQ---GYYLSEDTRICEDIDECFAHPGVCG 1704
E I +CQ P +C GNC N T SF CEC + G + + C + F G+C
Sbjct: 255 EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL--LFWKRGICP 310
Query: 1705 PGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC---ENELPFNVTKRM 1761
N+ YT CP NG + + C NGT C N++ M
Sbjct: 311 -----NSSSAYTYECPKGSSSQNGETDVSEFSLVPCQ---NGTDCIKISNDV-------M 355
Query: 1762 CCC----TYNVGKAWNKPCEPCPTPGTADFKTI-----CGNIPGFTFDIHTGKAVDIDEC 1812
C C T + K+ CE P A K C I GFT + + KA ID C
Sbjct: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT-EKNCEKA--IDHC 412
Query: 1813 KEIPGICANGV-CINQIGSFRCECPTGFSYN------DLLLVCEDIDECS-NGDNLCQRN 1864
K + C N C N IG F+ C G + N ++ L+ + + C +CQ
Sbjct: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDK 472
Query: 1865 ADC-------INSPGSYRCECA----AGFKLSPNGACV----------DRNECLEIPN-- 1901
+ GS +C A F L+ N C D N P+
Sbjct: 473 GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAAN--CTEDATYVNDPEDNNSSCWFPHEG 530
Query: 1902 ---VCSHGL-CVDLQGS----YQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVG 1953
+C++G C+ + S Y C + T +EC+ CK+ +
Sbjct: 531 TKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE----AVCKDEIN 586
Query: 1954 SYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKN 2013
C C +++D C + +G C + C + YE +N
Sbjct: 587 RPRCSC--SLSYIGRLCVVNVDYCLGNHS-ISVHGLCLALSHNCNCSGLQRYE-----RN 638
Query: 2014 C--IDTNECVALPGSCSPGTCQ-NLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLF 2069
IDT +C + SC GT +L G F C PG+ K C IDI+EC P C
Sbjct: 639 ICEIDTEDCKS--ASCKNGTTSTHLRGYFFRKCVPGF--KGTQCEIDIDECASHP--CKN 692
Query: 2070 GS-CTNTPG--------------GFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCS 2114
G+ C + PG GF CLC PG+V G RC E+ S
Sbjct: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV----GIRCEQDIDDCILNACEHN--S 746
Query: 2115 VPKAFNTTKAKCCCSKMPG---EGWGDPCELCPKDDEVAFQDL-----CPYGHGTVPSLH 2166
K + + C S G E + C++ P + DL C G
Sbjct: 747 TCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQ-- 804
Query: 2167 DTREDVNECLESPGICSNGQCINTD---GSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
+ E++NEC P C NG + G F C CP Y + R D + NPC
Sbjct: 805 NCSEEINECDSDP--CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD--LLHNPC 860
Query: 2224 -GNGTCTNVIGSFE-CNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCP 2280
N TC ++ + + C C E FE NCE D+ +C C + ++ C C
Sbjct: 861 RNNSTCLALVDANQHCICREEFEG---KNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR 917
Query: 2281 IGYALREDQKMCK-DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VD 2338
G++ +C+ +++EC+ C++ G C +L F C C P G C +D
Sbjct: 918 PGFS----GSLCEIEINECSS--EPCKNNGT-CVDLTNRFFCNCEPEY----HGPFCELD 966
Query: 2339 ENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT---ECLDN---RQGLCFAEVLQ 2392
N+C+ P + E CV Y C C G+ + ECL G+C +
Sbjct: 967 VNKCKISPCLDEEN-CVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
Query: 2393 TICQMASS--SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDI 2450
C S + T + C G EL +Y C DG
Sbjct: 1026 YTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELIN-----EYPCSCD------ADGTST 1074
Query: 2451 DECKVMPNLCTNGQCIN------TMGSFRCFCKVGYTTDISGTSCI-DLDECSQSPKPCN 2503
+CK+ N CT+ C+N + F C C GYT G C +D C++ P+ +
Sbjct: 1075 -QCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYT----GAYCEKSIDNCAE-PELNS 1128
Query: 2504 YICKN----TEG---SYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFT 2555
IC N +G ++ C C G+ G+ C+ +++EC + C + + G+
Sbjct: 1129 VICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPCLHGADCEDHINGYV 1184
Query: 2556 CKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCED 2614
CKC PG++ HH C + EC P+ C + +N PGS +C C GF + GL C D
Sbjct: 1185 CKCQPGWSGHH--CENELEC--IPNSCVHELCMENEPGS-TCLCTPGFMTCSIGLLCGD 1238
Score = 184 bits (466), Expect = 1e-45
Identities = 310/1242 (24%), Positives = 432/1242 (34%), Gaps = 297/1242 (23%)
Query: 153 CMNGGTCADD------HCQCQKGYIGTYCGQ-PVCE-NGCQNGGRCIGPNR--------C 196
C G C + C CQ + G YC + C C+N G CI C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 197 ACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPA 256
C FTG C G C V G + I +C + P C
Sbjct: 243 VCHPPFTGKNCSEII--GQCQPHV---CFHGNCSNITSNSFIC--ECDEQFSGP--FCEV 293
Query: 257 QPQPC------RRGFIPNIR---TGACQ----------DVDECQAIPGICQGG-NCINTV 296
+PC +RG PN T C DV E +P CQ G +CI
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKIS 351
Query: 297 GSFECRCPAGHKQSETTQKCEDID-ECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDG 355
C C T C+ I C P + C Y C C G+ T +
Sbjct: 352 NDVMCIC----SPIFTDLLCKSIQTSCESFP-LRNNATCKKCEKDYPCSCISGF-TEKNC 405
Query: 356 SRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCC--CEPGRCWGIGTIPEACPVRGSEEY 413
+ ID + + L C + GR K C C CW + + +
Sbjct: 406 EKAIDHCKLLSINCLNEEWCFNII-GRF-KYVCIPGCTKNPCWFLKNVYLI--------H 455
Query: 414 RRLCMDGLPMGGIPGSAGSRP-------GGTGGNGFAPSGNGNGYG------PGGTGFIP 460
+ LC G+ GI G G G G G + Y ++
Sbjct: 456 QHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVN 515
Query: 461 IPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSS--YR 518
P N S G T +IC AN C C+ S YR
Sbjct: 516 DPEDNNSSCWFPHEG------------------TKEIC---ANGC---SCLSEEDSQEYR 551
Query: 519 CEC------NMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQA 572
C NM Y ++ D +EC D +N P C C + +
Sbjct: 552 YLCFLRWAGNM-YLENTTDD--QENECQHEAVCK-DEINRPR---CSCSLSYIG---RLC 601
Query: 573 CIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMC 632
+++D C+ N + +G C+ S C C+ G + +D ++C + + C NG
Sbjct: 602 VVNVDYCLGNHSISVHGLCLAL--SHNCNCS-GLQRYERNICEIDTEDCKSAS-CKNGTT 657
Query: 633 INE-DGSFKCICKPGFVLAPNGRYCT-DVDECQTPGICMNGH-CINSEGSFRCDCPPGLA 689
G F C PGF G C D+DEC + C NG CI+ G++ C
Sbjct: 658 STHLRGYFFRKCVPGF----KGTQCEIDIDECASHP-CKNGATCIDQPGNYFCQ------ 706
Query: 690 VGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNS 749
CV PF V C NP Y
Sbjct: 707 -------------------------CVPPFK--VVDGFSCLCNPGY-------------- 725
Query: 750 AEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCNCNSGYEPDASGRNC 808
VGI + +DI++C L+ C N C++L SY+C C S +E G C
Sbjct: 726 ----------VGIRCE-QDIDDCILNA--CEHNSTCKDLHLSYQCVCLSDWE----GNFC 768
Query: 809 I-DIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-C 866
+ +EC +N +N C + SY C C G+ T E+INEC+S+PC+NG C
Sbjct: 769 EQESNECKMNPCK-NNSTCTDLYKSYRCECTSGW---TGQNCSEEINECDSDPCMNGGLC 824
Query: 867 RNNL--GSFNCECSP-------------------GSKLSSTGLICIDSLKG-TCWLNIQD 904
+ G F C C P + +ST L +D+ + C +
Sbjct: 825 HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEG 884
Query: 905 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLAR--IKGVTCE-DVNECEV 961
CE+++ C L CE + C + R G CE ++NEC
Sbjct: 885 KNCEIDVKD-------CLFLSCQDYGDCEDMVNNFRC---ICRPGFSGSLCEIEINECSS 934
Query: 962 FPGVCP-NGRCVNSKGSFHCECPEGLTLDGTGRVC-LDIRMEQCYLKWDEDECIHPVPGK 1019
P C NG CV+ F C C + G C LD+ + DE+ C++ G
Sbjct: 935 EP--CKNNGTCVDLTNRFFCNCEP----EYHGPFCELDVNKCKISPCLDEENCVYRTDGY 988
Query: 1020 FRMDACCCAVGAAWGTECE----ECPK----------PGTKEYETLCPRGAGFANRGDVL 1065
C CA G G CE EC G Y C G
Sbjct: 989 ----NCLCAPGYT-GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSG---------F 1034
Query: 1066 TGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPD 1124
G + N+C + P C +G+C I + C C++ D C I++C P
Sbjct: 1035 FGTHCETNANDCLSNP--CLHGRCTELINEYPCSCDA----DGTSTQCKIKINDCTSIPC 1088
Query: 1125 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEG-SFQ 1182
+ G C + F C C GY +G K+ + E E N ++C GG CV+ G +F
Sbjct: 1089 M-NEGFCQKSAHGFTCICPRGY-TGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFD 1146
Query: 1183 CDCPLGHELSPSREDC-VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCT 1241
C C G S + C ++INECS S L C + I Y C C PG+ C
Sbjct: 1147 CRCLPGF----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGWSG----HHCE 1197
Query: 1242 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD 1283
+ EC I N C +E C C+ G+ G C D
Sbjct: 1198 NELEC-IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
Score = 137 bits (344), Expect = 2e-31
Identities = 210/918 (22%), Positives = 326/918 (35%), Gaps = 208/918 (22%)
Query: 1944 GNGTCKNTVGS--YNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFN-----EIGS 1996
G+G C + S Y+C C P F + C ++D CS F NG C N + +
Sbjct: 185 GHGKCLSEAWSKTYSCHCQPPFSGKY---CQELDACS--FKPCKNNGSCINKRENWDEQA 239
Query: 1997 FKCLCNEGYELTPDGKNCIDT-NECVALPGSCSPGTCQNL-EGSFRCICP-----PGYEV 2049
++C+C+ + GKNC + +C P C G C N+ SF C C P EV
Sbjct: 240 YECVCHPPFT----GKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
Query: 2050 KSENCIDINECDEDPNICLF---GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFT 2106
++ C+ + LF G C N+ + CP G S NG F
Sbjct: 294 SAKPCVSL----------LFWKRGICPNSSSAYTYECPKGSS-SQNGETDVS---EFSLV 339
Query: 2107 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 2166
+NG + + C CS + F DL
Sbjct: 340 PCQNGTDCIKIS---NDVMCICSPI-------------------FTDLLC---------- 367
Query: 2167 DTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG 2226
+ + ES + +N C + + C C G+ + + +D + N
Sbjct: 368 ---KSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT-EKNCEKAIDHCKLLSINCLNEE 423
Query: 2227 TCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR----CMNTF-GSYECTCPI 2281
C N+IG F+ C G P +++ Q+ C C + +E +
Sbjct: 424 WCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQL 483
Query: 2282 GYALREDQK----------MCKDLDECAEGLHDCESRGMMC-------KNLIGT------ 2318
G+A E +K + + E A ++D E C K +
Sbjct: 484 GFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLS 543
Query: 2319 ------FMCICPPGMARRPDGEGCVD--ENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2370
+ +C A E D ENEC+ C + I RC C+ +
Sbjct: 544 EEDSQEYRYLCFLRWAGNMYLENTTDDQENECQ------HEAVCKDEINRPRCSCSLSYI 597
Query: 2371 SSSSGTE---CLDNRQ----GLCFAEVLQTICQ-MASSSRNL--VTKSEC---CCDGGRG 2417
CL N GLC A C + RN+ + +C C G
Sbjct: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTT 657
Query: 2418 WGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQ-CINTMGSFRCFC 2476
H + + C G T DIDEC P C NG CI+ G++ C C
Sbjct: 658 STHL--------RGYFFRKCVPGFKGTQCEIDIDECASHP--CKNGATCIDQPGNYFCQC 707
Query: 2477 KVGYTTDISGTSCI------------DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQ 2524
+ + G SC+ D+D+C + N CK+ SYQC C +
Sbjct: 708 VPPFKV-VDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDW--- 763
Query: 2525 EDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCG 2583
+G C+ + +EC+ C + + C+C G+T + + + NEC S P + G
Sbjct: 764 -EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCS-EEINECDSDPCMNG 821
Query: 2584 AKGICQNT--PGSFSCECQRGFSLDATGLNCED-VDECDGNHR-CQHG--CQNIL-GGYR 2636
G+C + PG F C C + TG C + CD H C++ C ++
Sbjct: 822 --GLCHESTIPGQFVCLCPPLY----TGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH 875
Query: 2637 CGCPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACH- 2694
C C + ++ C +D +C + C + + +++C C GFS S C
Sbjct: 876 CICRE----EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFS----GSLCEI 927
Query: 2695 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTE---- 2750
++NECSS N C + + C C P Y+ G + LD
Sbjct: 928 EINECSSEPCKNNGTCVDLTNRFFCNCEPEYH---------------GPFCELDVNKCKI 972
Query: 2751 ---VDEENALSPEACYEC 2765
+DEEN + Y C
Sbjct: 973 SPCLDEENCVYRTDGYNC 990
Score = 130 bits (326), Expect = 2e-29
Identities = 111/398 (27%), Positives = 174/398 (43%), Gaps = 69/398 (17%)
Query: 508 GRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPC-TNGDCVNTPGSYYCKCHAGFQ 565
G C V+++RC C G+ C I+++EC+S PC NG CV+ ++C C +
Sbjct: 903 GDCEDMVNNFRCICRPGFSGSL---CEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYH 959
Query: 566 RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTT 624
+ +D+++C + L + TDG + C+C G+ G NC ++ DEC +
Sbjct: 960 GPFCE---LDVNKCKISPCLDEENCVYRTDG-YNCLCAPGYT----GINCEINLDECLSE 1011
Query: 625 NMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGSFRCD 683
+G+CI+ + C CK GF G +C T+ ++C + C++G C + C
Sbjct: 1012 PCLHDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLS-NPCLHGRCTELINEYPCS 1066
Query: 684 CPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQP 743
C DG ++ IK C + C N + CQ
Sbjct: 1067 CDA------DG---------TSTQCKIKINDC----------TSIPCMNEGF-----CQ- 1095
Query: 744 CPAKNSAEFHGLCSSGVGITVDGRDINECA---LDPDICANG-ICENLRG-SYRCNCNSG 798
K++ F +C G + I+ CA L+ IC NG IC + G ++ C C G
Sbjct: 1096 ---KSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPG 1152
Query: 799 YEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE 857
+ SG+ C I+I+EC + L C + Y C C PG+ CE+ EC
Sbjct: 1153 F----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGW----SGHHCENELECI 1203
Query: 858 SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
N CV+ C N C C+PG S GL+C D ++
Sbjct: 1204 PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIR 1241
Score = 120 bits (300), Expect = 3e-26
Identities = 132/546 (24%), Positives = 198/546 (36%), Gaps = 116/546 (21%)
Query: 108 NQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADDH--- 163
N+C + C+N+ + C C+SG C S+ I +C S CMNGG C +
Sbjct: 773 NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC-SEEINECDSDPCMNGGLCHESTIPG 831
Query: 164 ---CQCQKGYIGTYCGQ-----PVCENGCQNGGRCI----GPNRCACVYGFTGPQCERDY 211
C C Y G +C Q + N C+N C+ C C F G CE D
Sbjct: 832 QFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDV 891
Query: 212 RT---------GPCFTQVNNQMCQGQLTGIVC----TKTLCCATIGRAWGHPCEMCPAQP 258
+ G C VNN C +C + +LC I PC+
Sbjct: 892 KDCLFLSCQDYGDCEDMVNNFRC-------ICRPGFSGSLCEIEINECSSEPCKNNGTCV 944
Query: 259 QPCRRGFI---PNIRTGACQ-DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQ 314
R F P C+ DV++C+ P + + NC+ + C C G+ T
Sbjct: 945 DLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE-ENCVYRTDGYNCLCAPGY----TGI 999
Query: 315 KCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNG 373
CE ++DEC P + G C + + Y C C G+ G+ C + ++G
Sbjct: 1000 NCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLSNPCLHG 1054
Query: 374 RCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCM-DGLPMGGIPGSAGS 432
RC + + + C C+ GT + C ++ ++ CM +G G
Sbjct: 1055 RCTE----LINEYPCSCDAD-----GTSTQ-CKIKINDCTSIPCMNEGFCQKSAHGFTCI 1104
Query: 433 RPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILN 492
P G G + N P I + GG
Sbjct: 1105 CPRGYTG-AYCEKSIDNCAEPELNSVICLNGG---------------------------- 1135
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNG-DCVN 551
IC + RC+P S CE I+++EC+S+PC +G DC +
Sbjct: 1136 ----ICVDGPGHTFDCRCLPGFSGQFCE-------------ININECSSSPCLHGADCED 1178
Query: 552 TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTD 611
Y CKC G+ + C + ECI N C + C+ + C+C GF +
Sbjct: 1179 HINGYVCKCQPGW----SGHHCENELECIPNS--CVHELCMENEPGSTCLCTPGFMTCSI 1232
Query: 612 GKNCVD 617
G C D
Sbjct: 1233 GLLCGD 1238
Score = 100 bits (248), Expect = 3e-20
Identities = 70/217 (32%), Positives = 108/217 (49%), Gaps = 31/217 (14%)
Query: 502 ANLCLNGRCIPTVSSYRCECNMGYKQDANGDC----IDVDECTSNPCTN-GDCVNTPGSY 556
+N CL+GRC ++ Y C C DA+G I +++CTS PC N G C + +
Sbjct: 1048 SNPCLHGRCTELINEYPCSC------DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGF 1101
Query: 557 YCKCHAGFQRTPTKQACIDIDECIQ---NGVLCKNGR-CVNTDG-SFQCICNAGFELTTD 611
C C G+ +++ ID C + N V+C NG CV+ G +F C C GF
Sbjct: 1102 TCICPRGYTGAYCEKS---IDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS---- 1154
Query: 612 GKNC-VDHDECTTTNMCLNGM-CINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICM 669
G+ C ++ +EC+++ CL+G C + + C C+PG+ +G +C + EC P C+
Sbjct: 1155 GQFCEININECSSSP-CLHGADCEDHINGYVCKCQPGW----SGHHCENELEC-IPNSCV 1208
Query: 670 NGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTC 706
+ C+ +E C C PG G +C D R TC
Sbjct: 1209 HELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 92.4 bits (228), Expect = 6e-18
Identities = 150/653 (22%), Positives = 218/653 (33%), Gaps = 166/653 (25%)
Query: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVR 152
F C PG+K G QC + I + C C C G C +
Sbjct: 665 FFRKCVPGFK----GTQCEIDI--DECASHPCKNGATCIDQPGNYFCQCVPP------FK 712
Query: 153 CMNGGTCADDHCQCQKGYIGTYCGQPVCE---NGCQNGGRCIGPN---RCACVYGFTGPQ 206
++G +C C GY+G C Q + + N C++ C + +C C+ + G
Sbjct: 713 VVDGFSCL-----CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
Query: 207 CER---DYRTGPCFTQVNNQMCQGQLTGIVC------TKTLCCATIGRAWGHPC------ 251
CE+ + + PC NN C C T C I PC
Sbjct: 768 CEQESNECKMNPC---KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
Query: 252 --------------------------EMCPAQPQPCRRGFIPNIRTGACQ---------- 275
+C PCR A Q
Sbjct: 825 HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEG 884
Query: 276 -----DVDECQAIPGICQG-GNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGI 328
DV +C + CQ G+C + V +F C C G S CE +I+ECS P
Sbjct: 885 KNCEIDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFSGS----LCEIEINECSSEP-- 936
Query: 329 CE-TGECSNTVGSYFCVCPRGY--------VTSTDGSRCIDQRTGMCFSGLVNGRCAQEL 379
C+ G C + +FC C Y V S C+D+ C
Sbjct: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEE-----------NCVYRT 985
Query: 380 PGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCM-DGLPMGGIPGSAGSRPGGTG 438
G C C PG GI C + E C+ DG+ + GI G
Sbjct: 986 DG----YNCLCAPGYT-GIN-----CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFF 1035
Query: 439 GNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDIC 498
G + N +P + G + P + T C
Sbjct: 1036 GTHCETNAN----------------DCLSNPCLHGRCTELINEYPCSCD---ADGTSTQC 1076
Query: 499 KHHANLCLN------GRCIPTVSSYRCECNMGYK----QDANGDCIDVDECTSNPCTNGD 548
K N C + G C + + C C GY + + +C + E S C NG
Sbjct: 1077 KIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAE-PELNSVICLNGG 1135
Query: 549 -CVNTPG-SYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQCICNAG 605
CV+ PG ++ C+C GF + Q C I+I+EC + L C + + C C G
Sbjct: 1136 ICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPG 1190
Query: 606 FELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTD 658
+ G +C + EC N C++ +C+ + C+C PGF+ G C D
Sbjct: 1191 W----SGHHCENELEC-IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
Score = 75.5 bits (184), Expect = 7e-13
Identities = 71/285 (24%), Positives = 109/285 (38%), Gaps = 44/285 (15%)
Query: 108 NQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCAD--DH-- 163
N+C + C + + + C C+ G C + S C++ G C D +H
Sbjct: 968 NKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYT 1027
Query: 164 CQCQKGYIGTYC---GQPVCENGCQNGGRC---IGPNRCACVYGFTGPQCE---RDYRTG 214
C C+ G+ GT+C N C +G RC I C+C T QC+ D +
Sbjct: 1028 CDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSI 1086
Query: 215 PCFTQVNNQMCQGQLTGIVC------TKTLCCATIGRAW-----------GHPCEMCPAQ 257
PC +N CQ G C T C +I G C P
Sbjct: 1087 PC---MNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH 1143
Query: 258 PQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC 316
CR +P C+ +++EC + P + G +C + + + C+C G + C
Sbjct: 1144 TFDCR--CLPGFSGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGW----SGHHC 1196
Query: 317 EDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQ 361
E+ EC IP C C C+C G++T + G C D+
Sbjct: 1197 ENELEC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
Score = 51.6 bits (122), Expect = 1e-05
Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 15/79 (18%)
Query: 144 KSIQQCSVR------CMNGGTCADDH----CQCQKGYIGTYCGQPVCENG-CQNGGRCIG 192
K+I+ C V C N GTC D+ C+C + Y G C CEN C NG C+
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVP 2388
Query: 193 PNR----CACVYGFTGPQC 207
+ C C YG +GP C
Sbjct: 2389 KSGTDIVCLCPYGRSGPLC 2407
Score = 44.3 bits (103), Expect = 0.002
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 21/87 (24%)
Query: 144 KSIQQCS------VRCMNGGTCADD----HCQCQKGYIGTYCGQPV--CE------NGCQ 185
+S+ QC ++C NGGTC + +C C G+ G++C + V C+ + C
Sbjct: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
Query: 186 NGGRCIG-PN--RCACVYGFTGPQCER 209
G CI P+ C C G TG CE+
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 41.6 bits (96), Expect = 0.012
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1378 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDL----DECSNGTHQCSINAQCVNTPGSYR 1433
C +C+ S C+C GW G+ C + D + H CS A C++ P Y
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSF--CTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
Query: 1434 CACSEGFTG 1442
C C G TG
Sbjct: 2677 CFCPLGTTG 2685
Score = 39.3 bits (90), Expect = 0.057
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 1116 IDECRISPDL---CGSG-ICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC-R 1170
+ +C SP CG+G C+ + S C C G++ F + D P C R
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSR 2664
Query: 1171 GGTCVNTEGSFQCDCPLG 1188
G TC++ + C CPLG
Sbjct: 2665 GATCISLPHGYTCFCPLG 2682
Score = 38.5 bits (88), Expect = 0.098
Identities = 29/80 (36%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 487 GLTILNQTIDICKHHANLCLN-GRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT 545
G I N + C HH LC N G CI + CEC Y +G C +NPC
Sbjct: 2328 GKNIENCHVPWCAHH--LCRNNGTCISDNENLFCECPRLY----SGKLCQFASCENNPCG 2381
Query: 546 NG-DCVNTPGS-YYCKCHAG 563
NG CV G+ C C G
Sbjct: 2382 NGATCVPKSGTDIVCLCPYG 2401
Score = 38.5 bits (88), Expect = 0.098
Identities = 27/87 (31%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 267 PNIRTGACQDVDECQAIPGICQ----GGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC 322
P A + V +C A P GG CI + S C C G K S T+ D
Sbjct: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
Query: 323 SIIPGICETG-ECSNTVGSYFCVCPRG 348
P C G C + Y C CP G
Sbjct: 2656 HDPPHHCSRGATCISLPHGYTCFCPLG 2682
Score = 38.5 bits (88), Expect = 0.098
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 1/64 (1%)
Query: 1819 CANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1877
C NG CI S C C TG+ + D + + C R A CI+ P Y C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1878 CAAG 1881
C G
Sbjct: 2679 CPLG 2682
Score = 37.0 bits (84), Expect = 0.29
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 14/88 (15%)
Query: 2565 HHTACIDNNECGSQPSL---CGAKGICQNTPGSFSCECQRGFSLDATGLNC-EDVDECDG 2620
H A +C + P CG G C + S C C G+ G C E V CD
Sbjct: 2599 HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDP 2654
Query: 2621 N----HRCQHG--CQNILGGYRCGCPQG 2642
H C G C ++ GY C CP G
Sbjct: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Score = 37.0 bits (84), Expect = 0.29
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 1/59 (1%)
Query: 1663 GGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCICP 1720
GG CI + S C C G+ S T D P C G TC + YTC CP
Sbjct: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCP 2680
Score = 37.0 bits (84), Expect = 0.29
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 1360 KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQC 1419
KG + D D G + C C +F C C W GN C C N + C
Sbjct: 2866 KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLN--NLC 2921
Query: 1420 SINAQCV-NTPGSYRCACSEGFTG 1442
+ C+ + SY C C+ G+ G
Sbjct: 2922 LHQSLCIPDQSFSYSCLCTLGWVG 2945
Score = 36.2 bits (82), Expect = 0.49
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 1339 GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
G C + S C+C G+ T + D H+C A+C+++P + C C G
Sbjct: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Query: 1399 WIG 1401
G
Sbjct: 2683 TTG 2685
Score = 36.2 bits (82), Expect = 0.49
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 1850 DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH-GLC 1908
D D + G N C+ +C + ++ C C + C CL N+C H LC
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDW---AGNTCNQSVSCLN--NLCLHQSLC 2927
Query: 1909 V-DLQGSYQCICHNGF 1923
+ D SY C+C G+
Sbjct: 2928 IPDQSFSYSCLCTLGW 2943
Score = 35.8 bits (81), Expect = 0.64
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
Query: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG-TCTNVIGS-FECNCN 2240
+NG CI+ + + CECP Y+G C C NPCGNG TC G+ C C
Sbjct: 2346 NNGTCISDNENLFCECPR----LYSGKLC-QFASCE-NNPCGNGATCVPKSGTDIVCLCP 2399
Query: 2241 EGFEPGPMMNCED 2253
G GP+ C D
Sbjct: 2400 YG-RSGPL--CTD 2409
Score = 35.8 bits (81), Expect = 0.64
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 14/83 (16%)
Query: 1495 CSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN-----CVNGL-CV 1548
CS GTC +C C G++ G CT+ DP + C G C+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCI 2669
Query: 1549 NTPGRYECNCPPDFQLNPTGVGC 1571
+ P Y C CP L TG+ C
Sbjct: 2670 SLPHGYTCFCP----LGTTGIYC 2688
Score = 35.0 bits (79), Expect = 1.1
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%)
Query: 2019 ECVALPGSC----SPGTCQNLEGSFRCICPPGYEVKSENCID-INECDED---PNICLFG 2070
+C A P S + GTC S C C G+ K C + ++ CD + P+ C G
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW--KGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 2071 S-CTNTPGGFQCLCPPG 2086
+ C + P G+ C CP G
Sbjct: 2666 ATCISLPHGYTCFCPLG 2682
Score = 34.3 bits (77), Expect = 1.8
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 15/94 (15%)
Query: 810 DIDECLV----NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA 865
+I+ C V + L +NG C + + C CP Y + C+ CE+NPC NGA
Sbjct: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLY----SGKLCQ-FASCENNPCGNGA 2384
Query: 866 -CRNNLGS-FNCECSPGSKLSSTGLICIDSLKGT 897
C G+ C C G +G +C D++ T
Sbjct: 2385 TCVPKSGTDIVCLCPYG----RSGPLCTDAINIT 2414
Score = 34.3 bits (77), Expect = 1.8
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 1418 QCSINAQCVNTPGSYRCACSEGFTGDGFT--CSDVDECAENINLCENGQ-CLNVPGAYRC 1474
+C C+ + S C C+ G+ G T S D + + C G C+++P Y C
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
Query: 1475 ECEMGFT 1481
C +G T
Sbjct: 2678 FCPLGTT 2684
Score = 33.5 bits (75), Expect = 3.2
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 12/85 (14%)
Query: 766 GRDINECALDPDICANGICEN-----LRGS-YRCNCNSGYEPDASGRNCIDIDECLVNRL 819
G ++ +C D C C N + G+ + C C PD +G C CL N
Sbjct: 2868 GSNVGDC--DGTACGYNTCRNGGECTVNGTTFSCRCL----PDWAGNTCNQSVSCLNNLC 2921
Query: 820 LCDNGLCRNTPGSYSCTCPPGYVFR 844
L + + SYSC C G+V R
Sbjct: 2922 LHQSLCIPDQSFSYSCLCTLGWVGR 2946
Score = 33.1 bits (74), Expect = 4.1
Identities = 18/77 (23%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 536 VDECTSNPCT------NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG 589
V +C ++PC+ G C+ + S YC C G++ + + D C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 590 -RCVNTDGSFQCICNAG 605
C++ + C C G
Sbjct: 2666 ATCISLPHGYTCFCPLG 2682
Score = 32.7 bits (73), Expect = 5.4
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 5/80 (6%)
Query: 766 GRDINECALDPDI---CANG-ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLC 821
GR + +C P C NG C S CNC +G++ D C
Sbjct: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHC 2662
Query: 822 DNGL-CRNTPGSYSCTCPPG 840
G C + P Y+C CP G
Sbjct: 2663 SRGATCISLPHGYTCFCPLG 2682
Score = 32.7 bits (73), Expect = 5.4
Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 508 GRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP---CTNG-DCVNTPGSYYCKCHAG 563
G CI + +S C C G+K + + + +P C+ G C++ P Y C C G
Sbjct: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Score = 32.3 bits (72), Expect = 7.0
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDR-NEC---LEIPNVCSHG-LCVDLQGSY 1915
C CI S S C C G+K C + + C + P+ CS G C+ L Y
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWK---GSFCTETVSTCDPEHDPPHHCSRGATCISLPHGY 2675
Query: 1916 QCICHNG 1922
C C G
Sbjct: 2676 TCFCPLG 2682
Score = 32.0 bits (71), Expect = 9.2
Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 3/76 (3%)
Query: 1906 GLCVDLQGSYQCICHNGFKAS--QDQTMCMDVDECERHPCGNG-TCKNTVGSYNCLCYPG 1962
G C++ S C C G+K S + D + H C G TC + Y C C G
Sbjct: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Query: 1963 FELTHNNDCLDIDECS 1978
+ L I + S
Sbjct: 2683 TTGIYCEQALSISDPS 2698
Score = 32.0 bits (71), Expect = 9.2
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 1408 DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLN 1467
D D + G + C +C ++ C C + G+ TC+ C N+ L ++ +
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLNNLCLHQSLCIPD 2930
Query: 1468 VPGAYRCECEMGF 1480
+Y C C +G+
Sbjct: 2931 QSFSYSCLCTLGW 2943
Score = 32.0 bits (71), Expect = 9.2
Identities = 19/74 (25%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 107 GNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH--- 163
G C CRN C C +TC ++S+ + C++ C D
Sbjct: 2876 GTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFS 2934
Query: 164 --CQCQKGYIGTYC 175
C C G++G YC
Sbjct: 2935 YSCLCTLGWVGRYC 2948
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 242 bits (617), Expect = 4e-63
Identities = 252/932 (27%), Positives = 372/932 (39%), Gaps = 206/932 (22%)
Query: 1301 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 1360
N ++ L + G +A ++++ + CD N + + F H +
Sbjct: 173 NPEDRWKSLHFSGHVAHLELQIRV---RCDENYYSATCNKFCRPRNDFFGHYTCD---QY 226
Query: 1361 GTTGCTDV---DECE--IGAHNCDM-HASCLNIPGSFKCSCREGWIGNGI-KCIDLDECS 1413
G C D EC+ + C++ H C +PG +C C GW G +C+ C
Sbjct: 227 GNKACMDGWMGKECKEAVCKQGCNLLHGGC-TVPG--ECRCSYGWQGRFCDECVPYPGCV 283
Query: 1414 NGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS-DVDECAENINLCENGQCLNV-PGA 1471
+G+ CV ++C C + G C D++ C + G C+N P
Sbjct: 284 HGS--------CVEP---WQCNCETNW--GGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 1472 YRCECEMGFTPASDSRSCQDIDECSFQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNC 1530
YRC C G++ R+C+ + N C G +C+ +P F C C G+ +G C
Sbjct: 331 YRCTCPDGYS----GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPTC 382
Query: 1531 T-DIDECADPINCVNGLCVNTPGRYECNCPPDF-----QLNPT---GVGCVD-----NRV 1576
DIDECA G CV+ +EC CP + QL+ G C++ N +
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLI 442
Query: 1577 GNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGG 1636
G Y P G N I V R C G C+ VN Y +CP G
Sbjct: 443 GGYYCDCIP---GWKGINCHINVNDCRGQC------QHGGTCKDL--VNG--YQCVCPRG 489
Query: 1637 EGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDE 1695
G R + + DEC P GG C + F C CPQG+ +CE D+D
Sbjct: 490 FGGRHCEL-----ERDECASSP-CHSGGLCEDLADGFHCHCPQGF----SGPLCEVDVDL 539
Query: 1696 CFAHPGVCGPGT-CYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELP 1754
C P C G CYN G+Y C CP ++ GG NC
Sbjct: 540 C--EPSPCRNGARCYNLEGDYYCACPDDF----GGKNC---------------------- 571
Query: 1755 FNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKE 1814
+ P EPC PG A C I G D G
Sbjct: 572 ------------------SVPREPC--PGGA-----CRVIDGCGSDAGPG---------- 596
Query: 1815 IPGICANGV------CINQI-GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC 1867
+PG A+GV C++Q G+F C C +GF+ E+ID+C C+ C
Sbjct: 597 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGT---YCHENIDDCLG--QPCRNGGTC 651
Query: 1868 INSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFKAS 1926
I+ ++RC C +G++ G D N +P+ C S G C DL + C C +G+K
Sbjct: 652 IDEVDAFRCFCPSGWE----GELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKG- 706
Query: 1927 QDQTMCMDVDECERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVC 1985
+T +C+ + C N GTC ++ ++ C C PG++ + C S
Sbjct: 707 --KTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK---GSTCAVAKNSSCLPNPCV 761
Query: 1986 RNGRCFNEIGSFKCLCNEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICP 2044
G C SF C+C +G+E G+ C +TN+C LP + G C + FRC C
Sbjct: 762 NGGTCVGSGASFSCICRDGWE----GRTCTHNTNDCNPLP-CYNGGICVDGVNWFRCECA 816
Query: 2045 PGYEVKSENC-IDINECDEDPNICLFG-SCTNTPGGFQCLCPPGFV------LSDNGRRC 2096
PG+ +C I+I+EC P C +G +C + G++C CPPG + GR C
Sbjct: 817 PGF--AGPDCRINIDECQSSP--CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSC 872
Query: 2097 FDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCP 2156
+ F + C+ + + + CSK+ GW PC L + + ++ Q CP
Sbjct: 873 WSRGTPFPHGSSWVEDCNSCRCLDGRRD---CSKV-WCGW-KPCLLAGQPEALSAQ--CP 925
Query: 2157 YGHGTVPSLHDTREDVNECLE-SPGICSNGQC 2187
G CLE +PG C C
Sbjct: 926 LG--------------QRCLEKAPGQCLRPPC 943
Score = 204 bits (518), Expect = 1e-51
Identities = 196/723 (27%), Positives = 294/723 (40%), Gaps = 128/723 (17%)
Query: 2060 CDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAF 2119
C + N+ L G CT PG +C C G+ GR C + + +G C P
Sbjct: 245 CKQGCNL-LHGGCT-VPG--ECRCSYGW----QGRFC---DECVPYPGCVHGSCVEPWQC 293
Query: 2120 N--TTKAKCCCSK-MPGEGWGDPCE---LCPKDDEVAFQDLCPYGHGTVPSLHDTREDVN 2173
N T C K + G PC C + ++ CP G+ S + + +
Sbjct: 294 NCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCEKAEH 349
Query: 2174 ECLESPGICSNG-QCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCG-NGTCTN 2230
C +P C+NG C F C CP G++ G C +D DEC+ NPC GTC +
Sbjct: 350 ACTSNP--CANGGSCHEVPSGFECHCPSGWS----GPTCALDIDECA-SNPCAAGGTCVD 402
Query: 2231 VIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 2289
+ FEC C E + C+ D NEC P L AF C N G Y C C G+
Sbjct: 403 QVDGFECICPEQWVGA---TCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGW------ 453
Query: 2290 KMCKDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTK 2345
K ++ C ++DC + G CK+L+ + C+CP G G C ++ +EC +
Sbjct: 454 ---KGIN-CHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG----GRHCELERDECASS 505
Query: 2346 PGICEN-GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNL 2404
P C + G C ++ + C C +GF SG C + LC + C+ + NL
Sbjct: 506 P--CHSGGLCEDLADGFHCHCPQGF----SGPLC-EVDVDLC----EPSPCRNGARCYNL 554
Query: 2405 VTKSECCCD---GGRGWGHQCELCP-----------------LPGTAQYKKICPHGPGYT 2444
C C GG+ E CP +PGTA PHG +
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 2445 TDG-----------------RDIDECKVMPNLCTN-GQCINTMGSFRCFCKVGYTTDISG 2486
G +ID+C P C N G CI+ + +FRCFC G+ ++
Sbjct: 615 QPGGNFSCICDSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGWEGELCD 672
Query: 2487 TSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLD-ECQTKQHNCQF 2545
T + ++C P C + + C+C G+ GKTC + +C +
Sbjct: 673 T---NPNDCLPDPCHSRGRCYDLVNDFYCACDDGW----KGKTCHSREFQCDAYTCSNGG 725
Query: 2546 LCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL 2605
C ++ F C CPPG+ A N+ C P+ C G C + SFSC C+ G+
Sbjct: 726 TCYDSGDTFRCACPPGWKGSTCAVAKNSSC--LPNPCVNGGTCVGSGASFSCICRDGWE- 782
Query: 2606 DATGLNC-EDVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC-VDENECSNP 2661
G C + ++C+ C +G C + + +RC C G + C ++ +EC +
Sbjct: 783 ---GRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCECAPG----FAGPDCRINIDECQSS 834
Query: 2662 NACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGC 2721
A+C + + Y+C+CP G + + C S P +G S E C C
Sbjct: 835 PCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC 894
Query: 2722 PPG 2724
G
Sbjct: 895 LDG 897
Score = 190 bits (483), Expect = 2e-47
Identities = 212/772 (27%), Positives = 301/772 (38%), Gaps = 160/772 (20%)
Query: 1136 GSFECE------CFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGH 1189
G + C+ C +G+ M K C + C++ L GG V E C C G
Sbjct: 219 GHYTCDQYGNKACMDGW-----MGKECKEA-VCKQGCNLLHGGCTVPGE----CRCSYGW 268
Query: 1190 ELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNP---GYQATPDRQGCTDIDEC 1246
+ ++CV C +G CV +QC+C G D C C
Sbjct: 269 Q-GRFCDECVPYPGCV-------HGSCVE---PWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1247 MIMNGGCDTQCTNSE-GSYECSCSEGYALMPDGRSCADIDE-CENNPDICDGGQCTNIPG 1304
NGG C N+E Y C+C +GY+ GR+C + C +NP +GG C +P
Sbjct: 318 T--NGGT---CINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPS 367
Query: 1305 EYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMF-GECENTKGSFICHCQLGYSVKKGT 1362
+ C C G+ TC +D++EC SN C G C + F C C + G
Sbjct: 368 GFECHCPSGWSG----PTCALDIDEC--ASNPCAAGGTCVDQVDGFECICPEQW---VGA 418
Query: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSI 1421
T D +ECE C SC N+ G + C C GW GI C I++++C QC
Sbjct: 419 TCQLDANECE--GKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCRG---QCQH 471
Query: 1422 NAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 1481
C + Y+C C GF G + DECA + G C ++ + C C GF+
Sbjct: 472 GGTCKDLVNGYQCVCPRGFGGRHCEL-ERDECASS-PCHSGGLCEDLADGFHCHCPQGFS 529
Query: 1482 PASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPI 1540
C+ D+D C C NL G ++C C D D G NC+ E
Sbjct: 530 ----GPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD----DFGGKNCSVPRE----- 576
Query: 1541 NCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVG 1600
C G C G C + T V G C + P G+ S C++ G
Sbjct: 577 PCPGGACRVIDG---CGSDAGPGMPGTAASGVCGPHGRCVSQ--PGGNFSCICDS----G 627
Query: 1601 VSRSSCCCSLGKAWGNPCE---TCPPVNSTE-YYTLCPGG-EGFRPNPITIILEDIDECQ 1655
+ + C ++ G PC TC ++ + + CP G EG L D +
Sbjct: 628 FTGTYCHENIDDCLGQPCRNGGTC--IDEVDAFRCFCPSGWEG--------ELCDTNPND 677
Query: 1656 ELPGLCQG-GNCINTFGSFQCECPQGYYLSEDTRICEDID-ECFAHPGVCGPGTCYNTLG 1713
LP C G C + F C C G+ + C + +C A+ G GTCY++
Sbjct: 678 CLPDPCHSRGRCYDLVNDFYCACDDGW----KGKTCHSREFQCDAYTCSNG-GTCYDSGD 732
Query: 1714 NYTCICPPEYMQVNGGHNCMDMRKSFCYRS--YNGTTCENELPFNVTKRMCCCTYNVGKA 1771
+ C CPP + G C + S C + NG TC VG
Sbjct: 733 TFRCACPPGWK----GSTCAVAKNSSCLPNPCVNGGTC------------------VGSG 770
Query: 1772 WNKPCEPCPTPGTADFKTIC-GNIPGFTFDIHTGKAVDIDECKEIPGICAN-GVCINQIG 1829
A F IC G T +T ++C +P C N G+C++ +
Sbjct: 771 -------------ASFSCICRDGWEGRTCTHNT------NDCNPLP--CYNGGICVDGVN 809
Query: 1830 SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAG 1881
FRCEC GF+ D + +IDEC + C A C++ YRC C G
Sbjct: 810 WFRCECAPGFAGPDCRI---NIDECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 187 bits (475), Expect = 1e-46
Identities = 186/697 (26%), Positives = 266/697 (38%), Gaps = 147/697 (21%)
Query: 695 RVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYG-FGEPCQPCPAKNSAEFH 753
+ C+D M C + K C G EC C+ G F + C P P H
Sbjct: 229 KACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGC----VH 284
Query: 754 GLC---------SSGVGITVDGRDINECALDPDICANGICENLR-GSYRCNCNSGYEPDA 803
G C ++ G+ D +D+N C G C N YRC C GY
Sbjct: 285 GSCVEPWQCNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY---- 339
Query: 804 SGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT------------------ 845
SGRNC + + + G C P + C CP G+ T
Sbjct: 340 SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGT 399
Query: 846 ----------------ETETCE-DINECESNPCVNG-ACRNNLGSFNCECSPGSKLSSTG 887
TC+ D NECE PC+N +C+N +G + C+C PG K G
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 455
Query: 888 LIC---IDSLKGTCWLNIQDSRCEVNING-------------ATLKSECCATLGAAWGSP 931
+ C ++ +G C C+ +NG L+ + CA+ G
Sbjct: 456 INCHINVNDCRGQCQ---HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGL 512
Query: 932 CERCE--LDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLT 987
CE CP+G + G CE DV+ CE P C NG RC N +G ++C CP+
Sbjct: 513 CEDLADGFHCHCPQGFS---GPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCACPD--- 564
Query: 988 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 1047
D G+ C R P PG C V G++ PGT
Sbjct: 565 -DFGGKNCSVPR--------------EPCPGG------ACRVIDGCGSDAGP-GMPGTAA 602
Query: 1048 YETLCPRGAGFANRG--------DVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCR 1099
P G + G TG +++I++C P G C + + +F+C
Sbjct: 603 SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP-CRNGGTCIDEVDAFRCF 661
Query: 1100 CNSGFALDMEERNCTDIDECRISPDLCGS-GICVNTPGSFECECFEGYESGFMMMKNCMD 1158
C SG+ ++ + N D PD C S G C + F C C +G++ K C
Sbjct: 662 CPSGWEGELCDTNPND-----CLPDPCHSRGRCYDLVNDFYCACDDGWKG-----KTCHS 711
Query: 1159 IDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKC 1216
E + + C GGTC ++ +F+C CP G + S C S N C N G C
Sbjct: 712 -REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGS----TCAVAKNSSCLPNPCVNGGTC 766
Query: 1217 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 1276
V ++ C C G++ D + NGG C + + C C+ G+A P
Sbjct: 767 VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI---CVDGVNWFRCECAPGFA-GP 822
Query: 1277 DGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDG 1313
D R +IDEC+++P G C + YRC C G
Sbjct: 823 DCR--INIDECQSSP-CAYGATCVDEINGYRCSCPPG 856
Score = 185 bits (470), Expect = 5e-46
Identities = 170/579 (29%), Positives = 236/579 (40%), Gaps = 136/579 (23%)
Query: 2173 NECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTN 2230
+EC+ PG C +G C+ ++C C + G+ C D + C +PC NG TC N
Sbjct: 274 DECVPYPG-CVHGSCVEP---WQCNCETNWG----GLLCDKDLNYCGSHHPCTNGGTCIN 325
Query: 2231 VI-GSFECNCNEGFEPGPMMNCEDINE-CAQNPLLCAFRCMNTFGSYECTCPIGYALRED 2288
+ C C +G+ NCE C NP C +EC CP G++
Sbjct: 326 AEPDQYRCTCPDGYSG---RNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS---G 379
Query: 2289 QKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPG 2347
D+DECA + C + G C + + F CICP G C +D NEC KP
Sbjct: 380 PTCALDIDECAS--NPCAAGGT-CVDQVDGFECICPEQWV----GATCQLDANECEGKP- 431
Query: 2348 ICENG-RCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVT 2406
C N C N+IG Y C+C G++ G C N C + CQ + ++LV
Sbjct: 432 -CLNAFSCKNLIGGYYCDCIPGWK----GINCHINVND-CRGQ-----CQHGGTCKDLVN 480
Query: 2407 KSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC-TNGQC 2465
G+QC +CP G G + DEC P C + G C
Sbjct: 481 ------------GYQC-------------VCPRGFGGRHCELERDECASSP--CHSGGLC 513
Query: 2466 INTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQ 2524
+ F C C G+ SG C +D+D C SP C N EG Y C+CP +
Sbjct: 514 EDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF--- 566
Query: 2525 EDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPS---- 2580
GK C E CP G AC + CGS
Sbjct: 567 -GGKNCSVPRE---------------------PCPGG------ACRVIDGCGSDAGPGMP 598
Query: 2581 ------LCGAKGICQNTPG-SFSCECQRGFSLDATGLNC-EDVDECDGNHRCQHG--CQN 2630
+CG G C + PG +FSC C GF TG C E++D+C G C++G C +
Sbjct: 599 GTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDDCLGQP-CRNGGTCID 653
Query: 2631 ILGGYRCGCPQGYIQHYQWNQC-VDENECSNPNACGSAS-CYNTLGSYKCACPSGFSFDQ 2688
+ +RC CP G+ + C + N+C P+ C S CY+ + + CAC G+
Sbjct: 654 EVDAFRCFCPSGW----EGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACDDGWK--- 705
Query: 2689 FSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGY 2725
CH E C+ G C ++ + C CPPG+
Sbjct: 706 -GKTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGW 742
Score = 182 bits (463), Expect = 3e-45
Identities = 197/750 (26%), Positives = 293/750 (39%), Gaps = 162/750 (21%)
Query: 1670 FGSFQCE------CPQGYYLSE-DTRICEDIDEC-FAHPGVCGPGTC---YNTLGNYTCI 1718
FG + C+ C G+ E +C+ C H G PG C Y G +
Sbjct: 218 FGHYTCDQYGNKACMDGWMGKECKEAVCKQ--GCNLLHGGCTVPGECRCSYGWQGRFCDE 275
Query: 1719 CPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEP 1778
C P V+G +C++ + C ++ G C+ +L + C +++ P
Sbjct: 276 CVPYPGCVHG--SCVEPWQCNCETNWGGLLCDKDLNY-------CGSHH----------P 316
Query: 1779 CPTPGTA------DFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGS-F 1831
C GT ++ C D ++G+ + E CANG +++ S F
Sbjct: 317 CTNGGTCINAEPDQYRCTCP-------DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGF 369
Query: 1832 RCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGAC- 1890
C CP+G+S L DIDEC++ N C C++ + C C + C
Sbjct: 370 ECHCPSGWSGPTCAL---DIDECAS--NPCAAGGTCVDQVDGFECICPEQWV---GATCQ 421
Query: 1891 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKN 1950
+D NEC P + + C +L G Y C C G+K ++V++C GTCK+
Sbjct: 422 LDANECEGKPCLNAFS-CKNLIGGYYCDCIPGWKGINCH---INVNDCRGQCQHGGTCKD 477
Query: 1951 TVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTP 2009
V Y C+C GF H L+ DEC+S C + G C + F C C +G+
Sbjct: 478 LVNGYQCVCPRGFGGRHCE--LERDECAS---SPCHSGGLCEDLADGFHCHCPQGF---- 528
Query: 2010 DGKNC-IDTNECVALPGSCSPGT-CQNLEGSFRCICPPGYEVKSEN----------CIDI 2057
G C +D + C P C G C NLEG + C CP + K+ + C I
Sbjct: 529 SGPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVI 586
Query: 2058 NECDED----------PNIC-LFGSCTNTPGG-FQCLCPPGFVLSDNGRRCFDTRQSFCF 2105
+ C D +C G C + PGG F C+C GF ++C
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT------------GTYCH 634
Query: 2106 TNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSL 2165
N ++ C P G C D+ AF+ CP G L
Sbjct: 635 ENIDD-----------------CLGQPCRN-GGTC----IDEVDAFRCFCP--SGWEGEL 670
Query: 2166 HDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTD-ECSIGNPCG 2224
DT + N+CL P S G+C + F C C G+ G C + +C
Sbjct: 671 CDT--NPNDCLPDP-CHSRGRCYDLVNDFYCACDDGWK----GKTCHSREFQCDAYTCSN 723
Query: 2225 NGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYA 2284
GTC + +F C C G++ G + C NP + C+ + S+ C C G+
Sbjct: 724 GGTCYDSGDTFRCACPPGWK-GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE 782
Query: 2285 LREDQKMCKDLDECAEGLHDCES----RGMMCKNLIGTFMCICPPGMARRPDGEGC-VDE 2339
R C +DC G +C + + F C C PG A G C ++
Sbjct: 783 GR----------TCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA----GPDCRINI 828
Query: 2340 NECRTKPGICENG-RCVNIIGSYRCECNEG 2368
+EC++ P C G CV+ I YRC C G
Sbjct: 829 DECQSSP--CAYGATCVDEINGYRCSCPPG 856
Score = 179 bits (453), Expect = 5e-44
Identities = 195/717 (27%), Positives = 280/717 (39%), Gaps = 180/717 (25%)
Query: 640 KCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPP---GLAVGMDGRV 696
+C C G+ GR+C DEC C++G C+ ++C+C GL D
Sbjct: 261 ECRCSYGW----QGRFC---DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDLNY 310
Query: 697 CVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC 756
C H C G G C+ P + C C PD G C+
Sbjct: 311 CGSHH---PCTNG---GTCINAEPD---QYRCTC--PDGYSGRNCEKAE----------- 348
Query: 757 SSGVGITVDGRDINECALDPDICANG-ICENLRGSYRCNCNSGYEPDASGRNC-IDIDEC 814
+ C +P CANG C + + C+C SG+ SG C +DIDEC
Sbjct: 349 -------------HACTSNP--CANGGSCHEVPSGFECHCPSGW----SGPTCALDIDEC 389
Query: 815 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPCVNG-ACRNNLGS 872
N G C + + C CP +V TC+ D NECE PC+N +C+N +G
Sbjct: 390 ASNPCAA-GGTCVDQVDGFECICPEQWV----GATCQLDANECEGKPCLNAFSCKNLIGG 444
Query: 873 FNCECSPGSKLSSTGLIC---IDSLKGTCWLNIQDSRCEVNING-------------ATL 916
+ C+C PG K G+ C ++ +G C C+ +NG L
Sbjct: 445 YYCDCIPGWK----GINCHINVNDCRGQCQ---HGGTCKDLVNGYQCVCPRGFGGRHCEL 497
Query: 917 KSECCATLGAAWGSPCERCE--LDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCV 972
+ + CA+ G CE CP+G + G CE DV+ CE P C NG RC
Sbjct: 498 ERDECASSPCHSGGLCEDLADGFHCHCPQGFS---GPLCEVDVDLCE--PSPCRNGARCY 552
Query: 973 NSKGSFHCECPEGLTLDGTGRVCLDIRMEQCY-------------------------LKW 1007
N +G ++C CP+ D G+ C + E C +
Sbjct: 553 NLEGDYYCACPD----DFGGKNC-SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCG 607
Query: 1008 DEDECIHPVPGKFRMDACCCAVGAAWGTECEE---------CPKPGT-----KEYETLCP 1053
C+ G F +C C G GT C E C GT + CP
Sbjct: 608 PHGRCVSQPGGNF---SCICDSGFT-GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCP 663
Query: 1054 RGAGFANRGDVLTGRPFYKDINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERN 1112
G G++ P N+C P C + G+C + + F C C+ G+ + +
Sbjct: 664 SGW----EGELCDTNP-----NDC--LPDPCHSRGRCYDLVNDFYCACDDGW----KGKT 708
Query: 1113 CTDIDECRISPDLCGSGICVNTPGSFECECFEGYE-SGFMMMKNCMDIDECERNPLLCRG 1171
C + + G C ++ +F C C G++ S + KN C NP + G
Sbjct: 709 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKN----SSCLPNPCV-NG 763
Query: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK-CVNMIGTYQCSCNPG 1230
GTCV + SF C C G E R + N+C+ C NG CV+ + ++C C PG
Sbjct: 764 GTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLP--CYNGGICVDGVNWFRCECAPG 818
Query: 1231 YQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYA------LMPDGRSC 1281
+ A PD + +IDEC C + Y CSC G A ++ GRSC
Sbjct: 819 F-AGPDCR--INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSC 872
Score = 173 bits (439), Expect = 2e-42
Identities = 183/687 (26%), Positives = 268/687 (39%), Gaps = 129/687 (18%)
Query: 85 GPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCG--DGFCSRPNMCTCSSGQISSTCG 142
G C + C GW G +C +C+ C G C+ P C CS G C
Sbjct: 219 GHYTCDQYGNKACMDGWM----GKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC- 273
Query: 143 SKSIQQCSVR--CMNGGTCADDHCQCQKGYIGTYCGQPVCENG----CQNGGRCIGPN-- 194
+C C++G C C+ + G C + + G C NGG CI
Sbjct: 274 ----DECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329
Query: 195 --RCACVYGFTGPQCERDYR---TGPCFTQVNNQMCQGQLTGIVC------TKTLCCATI 243
RC C G++G CE+ + PC N C +G C + C I
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPC---ANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 244 GRAWGHPCEM---CPAQPQPCRRGF---IPNIRTGA-CQ-DVDECQAIPGICQGGNCINT 295
+PC C Q GF P GA CQ D +EC+ P + +C N
Sbjct: 387 DECASNPCAAGGTCVDQVD----GFECICPEQWVGATCQLDANECEGKPCL-NAFSCKNL 441
Query: 296 VGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETG-ECSNTVGSYFCVCPRGYVTST 353
+G + C C G K C ++++C G C+ G C + V Y CVCPRG+
Sbjct: 442 IGGYYCDCIPGWKGIN----CHINVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF---- 490
Query: 354 DGSRCIDQR----TGMCFSG-----LVNG---RCAQELPGRMTKMQC-CCEPG------R 394
G C +R + C SG L +G C Q G + ++ CEP R
Sbjct: 491 GGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGAR 550
Query: 395 CWGI-GTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTG---GNGFAPSGNGNG 450
C+ + G ACP + + C +P PG A G G G G +
Sbjct: 551 CYNLEGDYYCACP---DDFGGKNC--SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGV 605
Query: 451 YGPGGTGFIPIPGGN-------GFSPGVGGAGVGAGGQGPIITGLTILNQTI-------- 495
GP G + PGGN GF+ + P G T +++
Sbjct: 606 CGPHGR-CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS 664
Query: 496 ----DICKHHANLCL------NGRCIPTVSSYRCECNMGYKQDANGDCIDVD-ECTSNPC 544
++C + N CL GRC V+ + C C+ G+K C + +C + C
Sbjct: 665 GWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKT---CHSREFQCDAYTC 721
Query: 545 TNGD-CVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICN 603
+NG C ++ ++ C C G++ + A C+ N + G CV + SF CIC
Sbjct: 722 SNGGTCYDSGDTFRCACPPGWKGSTC--AVAKNSSCLPNPCV-NGGTCVGSGASFSCICR 778
Query: 604 AGFELTTDGKNCVDHDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCTDVDEC 662
G+E G+ C + C NG +C++ F+C C PGF P+ R ++DEC
Sbjct: 779 DGWE----GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA-GPDCRI--NIDEC 831
Query: 663 QTPGICMNGHCINSEGSFRCDCPPGLA 689
Q+ C++ +RC CPPG A
Sbjct: 832 QSSPCAYGATCVDEINGYRCSCPPGRA 858
Score = 145 bits (366), Expect = 6e-34
Identities = 115/391 (29%), Positives = 170/391 (43%), Gaps = 61/391 (15%)
Query: 2356 NIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN--LVTKSECCCD 2413
+ G Y C+ C+D G E + +C+ + + EC C
Sbjct: 216 DFFGHYTCD-------QYGNKACMDGWMG---KECKEAVCKQGCNLLHGGCTVPGECRCS 265
Query: 2414 GGRGW-GHQCELC-PLPGTAQYKKI------CPHGPGYTTDGRDIDECKVMPNLCTNG-Q 2464
GW G C+ C P PG + C G +D++ C + CTNG
Sbjct: 266 --YGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG-SHHPCTNGGT 322
Query: 2465 CINTM-GSFRCFCKVGYTTDISGTSCIDLDE-CSQSPKPCNYICKNTEGSYQCSCPRGYV 2522
CIN +RC C GY SG +C + C+ +P C ++C CP G+
Sbjct: 323 CINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW- 377
Query: 2523 LQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSL 2581
G TC D+DEC + CV+ + GF C CP + T +D NEC +P L
Sbjct: 378 ---SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGA-TCQLDANECEGKPCL 433
Query: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCG 2638
C+N G + C+C G+ G+NC +V++C G +CQHG C++++ GY+C
Sbjct: 434 NAFS--CKNLIGGYYCDCIPGWK----GINCHINVNDCRG--QCQHGGTCKDLVNGYQCV 485
Query: 2639 CPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACH-DV 2696
CP+G+ + C ++ +EC++ C + + C CP GFS C DV
Sbjct: 486 CPRGFGGRH----CELERDECASSPCHSGGLCEDLADGFHCHCPQGFS----GPLCEVDV 537
Query: 2697 NECSSSKNPCNYG--CSNTEGGYLCGCPPGY 2725
+ C S PC G C N EG Y C CP +
Sbjct: 538 DLCEPS--PCRNGARCYNLEGDYYCACPDDF 566
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 14/133 (10%)
Query: 90 GSRFHSYCCPGWK----TLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKS 145
G F C PGWK + + C+ C N C C G TC +
Sbjct: 731 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT 790
Query: 146 IQQCSVRCMNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC---IGPNR 195
+ C NGG C D C+C G+ G C + E + C G C I R
Sbjct: 791 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 850
Query: 196 CACVYGFTGPQCE 208
C+C G GP+C+
Sbjct: 851 CSCPPGRAGPRCQ 863
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 235 bits (600), Expect = 4e-61
Identities = 139/401 (34%), Positives = 204/401 (50%), Gaps = 45/401 (11%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCD----C 1185
C +T C CF GY+ +C D++EC CR G +C+NT GSF+C C
Sbjct: 190 CRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMIGTYQC----SCNPGYQATPDRQG- 1239
G+EL+ C DI+EC + C + C N +G+++C C G+ D G
Sbjct: 249 GTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALGN 305
Query: 1240 CTDIDECMIMNGGCDT--QCTNSEGSYEC-----SCSEGYALMPDGRSCADIDECENNPD 1292
C DI+EC+ ++ C C N+EGSY C +C GY L +G C D+DEC +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 1293 ICDGG-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICH 1351
C G +C N PG +RC C G+ + C+DVNEC +CENT GS++C
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW---IGNGIKCID 1408
C +G+ + C D++EC + C N+ GS++C CR G+ +G+ C D
Sbjct: 426 CSVGFRLSVDGRSCEDINECS----SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 1409 LDECS--NGTHQCSINAQCVNTPGSYRCAC-SEGF--TGDGFTCSDVDECAENINLCE-N 1462
+DEC+ G H CS +C+N PGS++C+C S G+ +G C D+DEC I+ C N
Sbjct: 482 IDECALPTGGHICSY--RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1463 GQCLNVPGAYRC---ECEMGFTPASDSR----SCQDIDECS 1496
C N+ G +RC EC + ++ +R C + ECS
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS 580
Score = 224 bits (570), Expect = 1e-57
Identities = 148/441 (33%), Positives = 199/441 (45%), Gaps = 70/441 (15%)
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEP-GPMMNCEDINECAQNPLLCAF--RCMNT 2271
D C G PC C + C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2272 FGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----C 2323
GS+ C +C GY L ED CKD+DEC G+H+C +C+N +G+F C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLP-DFICQNTLGSFRCRPKLQC 294
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGR-CVNIIGSYRCE-----CNEGFQSSSSGTE 2377
G + G C+D NEC + C G C+N GSY C+ C G+ + GT
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2378 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2437
C+D + +E C G GH+C PG+ + C
Sbjct: 354 CVDVDE--------------------CAPPAEPC-----GKGHRC--VNSPGSFR----C 382
Query: 2438 PHGPGYTTDGR-----DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL 2492
GY DG D++EC+ P +C NT+GS+ C C VG+ + G SC D+
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2493 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE-DGKTCKDLDEC--QTKQHNCQFLCVN 2549
+ECS S PC+ C N GSYQC C RGY L + DG TC+D+DEC T H C + C+N
Sbjct: 443 NECSSS--PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 2550 TLGGFTCKCPPG---FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC---ECQRGF 2603
G F C CP + C D +EC + C C N G F C EC +
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 2604 SLDATGLNCEDVDECDGNHRC 2624
A CE + C N C
Sbjct: 561 RRSA-ATRCERL-PCHENREC 579
Score = 214 bits (545), Expect = 1e-54
Identities = 140/399 (35%), Positives = 186/399 (46%), Gaps = 57/399 (14%)
Query: 2363 CECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQC 2422
C C G+Q S G C D + + + C++ S N V C D G G++
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHS----CRLGESCINTVGSFRCQRDSSCGTGYEL 254
Query: 2423 ELCPLPGTAQYKKICPHGPGYTTDG--RDIDECKV-MPNLCTNGQCINTMGSFRCF---- 2475
T D +DIDEC+ + N + C NT+GSFRC
Sbjct: 255 ---------------------TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 2476 CKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC-----SCPRGYVLQEDGK 2528
CK G+ D G +CID++EC PC + C NTEGSY C +C RGY L E+G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 2529 TCKDLDECQTKQHNCQ--FLCVNTLGGFTCKCPPG--FTQHHTACIDNNECGSQPS-LCG 2583
C D+DEC C CVN+ G F C+C G F C+D NEC P LCG
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 2584 AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGY 2643
K C+NT GS+ C C GF L G +CED++EC + C C N+ G Y+C C +GY
Sbjct: 413 HK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECANVYGSYQCYCRRGY 469
Query: 2644 -IQHYQWNQCVDENECSNPNACGSAS--CYNTLGSYKCACPS-GFSFDQFSSACHDVNEC 2699
+ C D +EC+ P S C N GS++C+CPS G+ C D++EC
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2700 SSSKNPC--NYGCSNTEGGYLC---GCPPGYYRVGQGHC 2733
+ + C N C N +GG+ C CP Y R C
Sbjct: 530 VTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRC 568
Score = 207 bits (528), Expect = 9e-53
Identities = 177/614 (28%), Positives = 242/614 (39%), Gaps = 122/614 (19%)
Query: 1166 PLLCRGGTC-----VNTEGSFQCDCPLGHELSPSREDC-----VDINECSLSDNLCRNGK 1215
PLL GG V+ + + C GH ++ ++DC + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG-GCDTQCTNSEGSYECSCSEGYAL 1274
C + + C+ DR C +G + T + C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDR--------CATPHGDNASLEATFVKRCCHC-CLLGRAA 119
Query: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD---------GFMASMDMKTCID 1325
G+SC + G QC + +R C G + D ++
Sbjct: 120 QAQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVE 168
Query: 1326 VNECD--LNSNICMFG-----ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
+ D LN C G +C +T +C C +GY + C DV+EC G+H+C
Sbjct: 169 EEQEDPYLNDR-CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1379 DMHASCLNIPGSFKC----SCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ SC+N GSF+C SC G+ + C D+DEC +G H C + C NT GS+R
Sbjct: 228 RLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 1434 C----ACSEGFTGDGF-TCSDVDECAENINLCENGQ-CLNVPGAYRCE-----CEMGFTP 1482
C C GF D C D++EC C G C+N G+Y C+ C G+
Sbjct: 288 CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 1483 ASDSRSCQDIDECS-FQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-P 1539
+ C D+DEC+ C G C N PG F C C GY D C D++EC P
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP 407
Query: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
C NT G Y C+C F+L+ G C D + C S C+ E
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INEC---------SSSPCSQECAN 456
Query: 1600 GVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
C C G Y L + + EDIDEC
Sbjct: 457 VYGSYQCYCRRG------------------YQL--------SDVDGVTCEDIDEC----A 486
Query: 1660 LCQGGN-----CINTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTL 1712
L GG+ CIN GSFQC CP GY L+ + R C+DIDEC C TC+N
Sbjct: 487 LPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQ 546
Query: 1713 GNYTCI---CPPEY 1723
G + C+ CP Y
Sbjct: 547 GGFRCLAFECPENY 560
Score = 204 bits (518), Expect = 1e-51
Identities = 120/284 (42%), Positives = 143/284 (50%), Gaps = 25/284 (8%)
Query: 2464 QCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY--ICKNTEGSYQC----SC 2517
QC +T C C VGY G SC D++EC C C NT GS++C SC
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 2518 PRGYVLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTCK----CPPGFTQHHTA-CI 2570
GY L ED +CKD+DEC++ HNC F+C NTLG F C+ C GF Q CI
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCI 307
Query: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCE-----CQRGFSLDATGLNCEDVDEC-DGNHRC 2624
D NEC S + C C NT GS++C+ C RG+ L+ G C DVDEC C
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 2625 Q--HGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACP 2681
H C N G +RC C GY CVD NEC P C NTLGSY C+C
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCS 427
Query: 2682 SGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
GF +C D+NECSSS PC+ C+N G Y C C GY
Sbjct: 428 VGFRLSVDGRSCEDINECSSS--PCSQECANVYGSYQCYCRRGY 469
Score = 196 bits (499), Expect = 2e-49
Identities = 136/449 (30%), Positives = 196/449 (43%), Gaps = 71/449 (15%)
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKP 2346
E+++ L++ G C+ + C++ +C C G DG C D NEC T
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQ---CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS 224
Query: 2347 GICENGR-CVNIIGSYRCE----CNEGFQ-SSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
C G C+N +GS+RC+ C G++ + + + +D + + ICQ
Sbjct: 225 HSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLG 284
Query: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR----DIDECKVM 2456
S K +C G+ D DI+EC +
Sbjct: 285 SFRCRPKLQC-----------------------------KSGFIQDALGNCIDINECLSI 315
Query: 2457 PNLCTNGQ-CINTMGSFRCF-----CKVGYTTDISGTSCIDLDECSQSPKPCN--YICKN 2508
C G CINT GS+ C C GY + GT C+D+DEC+ +PC + C N
Sbjct: 316 SAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 2509 TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN-CQFLCVNTLGGFTCKCPPGF--TQH 2565
+ GS++C C GY + C D++ECQ C C NTLG + C C GF +
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVD 435
Query: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL-DATGLNCEDVDEC---DGN 2621
+C D NEC S P C + C N GS+ C C+RG+ L D G+ CED+DEC G
Sbjct: 436 GRSCEDINECSSSP--CSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGG 491
Query: 2622 HRCQHGCQNILGGYRCGCP-QGYIQHYQWNQCVDENECSN--PNACGSASCYNTLGSYKC 2678
H C + C NI G ++C CP GY C D +EC N + +C+N G ++C
Sbjct: 492 HICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Query: 2679 ---ACPSGFSFDQFSSA----CHDVNECS 2700
CP + + CH+ ECS
Sbjct: 552 LAFECPENYRRSAATRCERLPCHENRECS 580
Score = 196 bits (497), Expect = 4e-49
Identities = 123/364 (33%), Positives = 169/364 (46%), Gaps = 48/364 (13%)
Query: 2412 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT--TDG---RDIDECKVMPNLCTNGQ-C 2465
C GG QC + +C GY +DG D++EC + C G+ C
Sbjct: 180 CRGGGPCKQQCR------DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESC 233
Query: 2466 INTMGSFRC----FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC---- 2515
INT+GSFRC C GY SC D+DEC C ++IC+NT GS++C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCK-----CPPGF--TQHH 2566
C G++ G C D++EC + C C+NT G +TC+ C G+ +
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 2567 TACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG--NHRC 2624
T C+D +EC CG C N+PGSF CEC+ G+ D C DV+EC C
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 2625 QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 2684
H C+N LG Y C C G+ C D NECS+ + C S C N GSY+C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-SPC-SQECANVYGSYQCYCRRGY 469
Query: 2685 SFDQFSSA-CHDVNECS--SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG--------HC 2733
C D++EC+ + + C+Y C N G + C CP YR+ C
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2734 VSGM 2737
V+G+
Sbjct: 530 VTGI 533
Score = 194 bits (494), Expect = 8e-49
Identities = 142/455 (31%), Positives = 203/455 (44%), Gaps = 74/455 (16%)
Query: 1803 TGKAVDIDECKEIPGI---CANG-----VCINQIGSFRCECPTGFSYNDLLLVCEDIDEC 1854
T K ++++E +E P + C G C + C C G+ + CED++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 1855 SNGDNLCQRNADCINSPGSYRCE----CAAGFKLSPNGACVDRNECLE-IPNVCSHGLCV 1909
G + C+ CIN+ GS+RC+ C G++L+ + +C D +EC I N +C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 1910 DLQGSYQCI----CHNGFKASQDQT-MCMDVDECER--HPCGNG-TCKNTVGSYNCL--- 1958
+ GS++C C +GF QD C+D++EC PC G TC NT GSY C
Sbjct: 281 NTLGSFRCRPKLQCKSGF--IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 1959 --CYPGFELTHNND-CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 2015
C G+ L C+D+DEC+ + RC N GSF+C C GY + C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCT 2073
D NEC PG C+N GS+ C C G+ V +C DINEC P C
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP---CSQECA 455
Query: 2074 NTPGGFQCLCPPGFVLSD-NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMP 2132
N G +QC C G+ LSD +G C D +C++P + +C +P
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDI-----------DECALPTGGHICSYRCI--NIP 502
Query: 2133 GEGWGDPCELCPKDDEVAFQDLCP-YGHGTVPSLHDTREDVNECLESPGICS-NGQCINT 2190
G +FQ CP G+ P+ + +D++EC+ CS N C N
Sbjct: 503 G----------------SFQCSCPSSGYRLAPNGRNC-QDIDECVTGIHNCSINETCFNI 545
Query: 2191 DGSFRC---ECPMGYNLDYT----GVRCVDTDECS 2218
G FRC ECP Y + C + ECS
Sbjct: 546 QGGFRCLAFECPENYRRSAATRCERLPCHENRECS 580
Score = 194 bits (493), Expect = 1e-48
Identities = 135/401 (33%), Positives = 185/401 (46%), Gaps = 58/401 (14%)
Query: 970 RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAV 1029
+C ++ C C G L G C D+ +ECI ++C V
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDV-----------NECITGSHSCRLGESCINTV 237
Query: 1030 GAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK- 1088
G+ C+ GT G LT KDI+EC++ C
Sbjct: 238 GSF---RCQRDSSCGT----------------GYELTEDNSCKDIDECESGIHNCLPDFI 278
Query: 1089 CRNTIGSFKCR----CNSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFECE-- 1141
C+NT+GSF+CR C SGF D NC DI+EC C G C+NT GS+ C+
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 1142 ---CFEGY---ESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPS 1194
C GY E G C+D+DEC C +G CVN+ GSF+C+C G+
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD 1254
CVD+NEC KC N +G+Y CSC+ G++ + D + C DI+EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCS 451
Query: 1255 TQCTNSEGSYECSCSEGYALMP-DGRSCADIDEC--ENNPDICDGGQCTNIPGEYRCLC- 1310
+C N GSY+C C GY L DG +C DIDEC IC +C NIPG ++C C
Sbjct: 452 QECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCP 510
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFIC 1350
G+ + + + C D++EC + C E C N +G F C
Sbjct: 511 SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 189 bits (480), Expect = 3e-47
Identities = 136/404 (33%), Positives = 181/404 (44%), Gaps = 71/404 (17%)
Query: 493 QTIDICKHHANLCLNGR-CIPTVSSYRCE----CNMGYKQDANGDCIDVDECTS---NPC 544
+ ++ C ++ C G CI TV S+RC+ C GY+ + C D+DEC S N
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 545 TNGDCVNTPGSYYCK----CHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTDGSFQ 599
+ C NT GS+ C+ C +GF + CIDI+EC+ C G C+NT+GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 600 C-----ICNAGFELTTDGKNCVDHDECT-TTNMCLNG-MCINEDGSFKCICKPGFVLAPN 652
C C G+ L +G CVD DEC C G C+N GSF+C CK G+
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 653 GRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
R C DV+ECQ PG C N+ GS+ C C G + +DGR C D
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI----------- 442
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT-VDG---R 767
+EC PC A + C G ++ VDG
Sbjct: 443 --------------NECS--------SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 768 DINECALDP--DICANGICENLRGSYRCNC-NSGYEPDASGRNCIDIDECLVNRLLCD-N 823
DI+ECAL IC+ C N+ GS++C+C +SGY +GRNC DIDEC+ C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 824 GLCRNTPGSYSC---TCPPGY----VFRTETETCEDINECESNP 860
C N G + C CP Y R E C + EC P
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLP 583
Score = 174 bits (440), Expect = 1e-42
Identities = 141/454 (31%), Positives = 187/454 (41%), Gaps = 75/454 (16%)
Query: 537 DECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTD 595
D C C +T C C G+Q +C D++ECI C+ G C+NT
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 596 GSFQC----ICNAGFELTTDGKNCVDHDECTT-TNMCL-NGMCINEDGSFKCI----CKP 645
GSF+C C G+ELT D +C D DEC + + CL + +C N GSF+C CK
Sbjct: 238 GSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 646 GFVLAPNGRYCTDVDECQTPGI-CMNGH-CINSEGSFRC-----DCPPGLAVGMDGRVCV 698
GF+ G C D++EC + C GH CIN+EGS+ C +C G + +G CV
Sbjct: 297 GFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 699 DTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSS 758
D EC G G C P E C +
Sbjct: 356 DV-------------------------DECAPPAEPCGKGHRCVNSPGSFRCE----CKT 386
Query: 759 GV---GITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL 815
G GI+ D+NEC P CEN GSY C+C+ G+ GR+C DI+EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 816 VNRLLCDNGLCRNTPGSYSCTCPPGY-VFRTETETCEDINEC---ESNPCVNGACRNNLG 871
+ + C N GSY C C GY + + TCEDI+EC + C N G
Sbjct: 447 SSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 872 SFNCEC-SPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGS 930
SF C C S G +L+ G C D C I+ ++ C G G
Sbjct: 504 SFQCSCPSSGYRLAPNGRNCQDI-----------DECVTGIHNCSINETCFNIQG---GF 549
Query: 931 PCERCELDTACPRGLA-RIKGVTCEDVNECEVFP 963
C E R A R + + C + EC P
Sbjct: 550 RCLAFECPENYRRSAATRCERLPCHENRECSKLP 583
Score = 168 bits (425), Expect = 8e-41
Identities = 139/464 (29%), Positives = 194/464 (41%), Gaps = 96/464 (20%)
Query: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHC----IC 1517
QC + C C +G+ SD SC+D++EC + + C G +C N G F C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1518 DDGYELDRTGGNCTDIDECADPI-NCV-NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
GYEL +C DIDEC I NC+ + +C NT G + C P Q G + +
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQCKS---GFIQDA 302
Query: 1576 VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
+GNC + N + + S C +G TC +N+ YT
Sbjct: 303 LGNC-----------IDINECLSI-----SAPCPIG-------HTC--INTEGSYTCQKN 337
Query: 1636 ----GEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
G G+ N D+DEC C +G C+N+ GSF+CEC GYY +R+C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 1691 EDIDECFAHPG-VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
D++EC +PG +CG C NTLG+Y C C + G +C D+ + + + C
Sbjct: 398 VDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC------SSSPC 450
Query: 1750 ENELPFNVTKRMCCCT--YNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 1807
E C C Y + CE
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCE------------------------------ 480
Query: 1808 DIDECKEIPG--ICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
DIDEC G IC+ CIN GSF+C CP +G+ C+DIDEC G + C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1865 ADCINSPGSYRC---ECAAGFKLSPNGACV-----DRNECLEIP 1900
C N G +RC EC ++ S C + EC ++P
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLP 583
Score = 164 bits (414), Expect = 2e-39
Identities = 141/506 (27%), Positives = 186/506 (36%), Gaps = 125/506 (24%)
Query: 2109 ENGKCSVPKAFNTTK--------AKCCCSKMPGEGWGDPCEL---------------CPK 2145
E +C+ P N + CC + G CE C K
Sbjct: 87 EQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVK 146
Query: 2146 DDEVAFQDLCPYGH-GTVPSLHDTRED--VNECLESPGICSNGQCINTDGSFRCECPMGY 2202
E D+ + + + +ED +N+ G C QC +T C C +GY
Sbjct: 147 SQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVCSCFVGY 205
Query: 2203 NLDYTGVRCVDTDECSIG----------------------NPCGNG-------------- 2226
L GV C D +EC G + CG G
Sbjct: 206 QLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDE 265
Query: 2227 ------------TCTNVIGSFEC----NCNEGFEPGPMMNCEDINECAQNPLLC--AFRC 2268
C N +GSF C C GF + NC DINEC C C
Sbjct: 266 CESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTC 325
Query: 2269 MNTFGSYEC-----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2323
+NT GSY C C GY L E+ C D+DECA C +G C N G+F C C
Sbjct: 326 INTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC-GKGHRCVNSPGSFRCEC 384
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2383
G CVD NEC+ PG +C N +GSY C C+ GF+ S G C D +
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINE 444
Query: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 2443
C + C N+ +C C G +L + G C
Sbjct: 445 --CSSSPCSQEC------ANVYGSYQCYCRRG------YQLSDVDGVT-----C------ 479
Query: 2444 TTDGRDIDECKVMP--NLCTNGQCINTMGSFRCFC-KVGYTTDISGTSCIDLDECSQSPK 2500
DIDEC + ++C+ +CIN GSF+C C GY +G +C D+DEC
Sbjct: 480 ----EDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIH 534
Query: 2501 PC--NYICKNTEGSYQC---SCPRGY 2521
C N C N +G ++C CP Y
Sbjct: 535 NCSINETCFNIQGGFRCLAFECPENY 560
Score = 149 bits (376), Expect = 4e-35
Identities = 175/634 (27%), Positives = 242/634 (38%), Gaps = 134/634 (21%)
Query: 592 VNTDGSFQCICNAGFELTTDGKNC-----VDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
V+ D + C G + T K+C + EC M C ++ C G
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKEC---RMVQEQCCHSQLEELHCAT--G 81
Query: 647 FVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF--RCD--CPPGLAVGMDGRVCVDTHM 702
LA + D C TP +G + E +F RC C G A G+ C + M
Sbjct: 82 ISLA------NEQDRCATP----HGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLM 131
Query: 703 RSTCYGGIKKGVCVRPFP------GAVTKSECCCA----------NPDYGFGEPCQPCPA 746
G + + CV+ G + +++ N G PC+
Sbjct: 132 VGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCR 191
Query: 747 KNSAEFHGLCSSGVGITVDG---RDINECALDPDICANG-ICENLRGSYRC----NCNSG 798
E C G + DG D+NEC C G C N GS+RC +C +G
Sbjct: 192 DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTG 251
Query: 799 YEPDASGRNCIDIDECLVNRLLC-DNGLCRNTPGSYSCT----CPPGYVFRTETETCEDI 853
YE +C DIDEC C + +C+NT GS+ C C G++ + C DI
Sbjct: 252 YEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI-QDALGNCIDI 309
Query: 854 NECES--NPCVNG-ACRNNLGSFNCE-----CSPGSKLSSTGLICIDSLKGTCWLNIQDS 905
NEC S PC G C N GS+ C+ C G L+ G C+D
Sbjct: 310 NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD------------- 356
Query: 906 RCEVNINGATLKSECCATLGAAWGSPCE-RCELDTACP-RGLARIKGVTCEDVNECEVFP 963
++ +E C SP RCE T G++R+ C DVNEC+ +P
Sbjct: 357 -----VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM----CVDVNECQRYP 407
Query: 964 GVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMD 1023
G +C N+ GS+ C C G L GR C DI +C EC +
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI--NECSSSPCSQECAN--------- 456
Query: 1024 ACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG- 1082
+G+ Y+ C RG ++ V +DI+EC G
Sbjct: 457 --------VYGS------------YQCYCRRGYQLSDVDGVTC-----EDIDECALPTGG 491
Query: 1083 -MCTYGKCRNTIGSFKCRC-NSGFALDMEERNCTDIDECRISPDLCG-SGICVNTPGSFE 1139
+C+Y +C N GSF+C C +SG+ L RNC DIDEC C + C N G F
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFR 550
Query: 1140 C---ECFEGYESGFMMMKN---CMDIDECERNPL 1167
C EC E Y C + EC + PL
Sbjct: 551 CLAFECPENYRRSAATRCERLPCHENRECSKLPL 584
Score = 144 bits (363), Expect = 1e-33
Identities = 118/398 (29%), Positives = 172/398 (43%), Gaps = 86/398 (21%)
Query: 273 ACQDVDECQAIPGICQ-GGNCINTVGSFECR----CPAGHKQSETTQKCEDIDEC-SIIP 326
+C+DV+EC C+ G +CINTVGSF C+ C G++ +E C+DIDEC S I
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIH 271
Query: 327 GICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM 386
C NT+GS+ RC + C SG + Q+ G
Sbjct: 272 NCLPDFICQNTLGSF---------------RCRPKL--QCKSGFI-----QDALGN---- 305
Query: 387 QCCCEPGRCWGIGTIPEACPVRGS---EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFA 443
C + C I CP+ + E C +P
Sbjct: 306 --CIDINECLSISA---PCPIGHTCINTEGSYTCQKNVPN-------------------- 340
Query: 444 PSGNGNGYGPGGTGFIPI--------PGGNGF----SPGVGGAGVGAGGQGPIITGLTIL 491
G G GT + + P G G SPG G G++ +
Sbjct: 341 -CGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYY---FDGISRM 396
Query: 492 NQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCV 550
++ C+ + +C T+ SY C C++G++ +G C D++EC+S+PC+ +C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ-ECA 455
Query: 551 NTPGSYYCKCHAGFQRTPTK-QACIDIDECI--QNGVLCKNGRCVNTDGSFQCIC-NAGF 606
N GSY C C G+Q + C DIDEC G +C + RC+N GSFQC C ++G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGY 514
Query: 607 ELTTDGKNCVDHDECTT--TNMCLNGMCINEDGSFKCI 642
L +G+NC D DEC T N +N C N G F+C+
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 99.0 bits (245), Expect = 6e-20
Identities = 99/327 (30%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 97 CCPGWKTLPGG------NQCIV--------PICRNSCGDGFCSRPNMCTCSSGQISSTCG 142
C G++ L G N+CI C N+ G C R + C + +++
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG-TGYELTEDNS 259
Query: 143 SKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNG------GRCIGPNRC 196
K I +C N C D CQ +G++ +P + C++G G CI N C
Sbjct: 260 CKDIDECESGIHN---CLPDFI-CQNT-LGSFRCRPKLQ--CKSGFIQDALGNCIDINEC 312
Query: 197 A-----CVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLT--GIVCTKTLCCATIGRAWG- 248
C G T E Y C V N L G C CA G
Sbjct: 313 LSISAPCPIGHTCINTEGSYT---CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK 369
Query: 249 -HPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H C P + C+ G+ + + C DV+ECQ PG G C NT+GS+ C C G
Sbjct: 370 GHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVG 429
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY-VTSTDGSRC--IDQRT 363
+ S + CEDI+ECS P C EC+N GSY C C RGY ++ DG C ID+
Sbjct: 430 FRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 364 GMCFSGLVNGRCAQELPGRMTKMQCCC 390
+ + RC +PG QC C
Sbjct: 487 LPTGGHICSYRCI-NIPG---SFQCSC 509
Score = 94.4 bits (233), Expect = 2e-18
Identities = 81/299 (27%), Positives = 113/299 (37%), Gaps = 66/299 (22%)
Query: 152 RCMNGGTCADDHCQCQKGYIGTYC----GQPVCENG--CQNGGRCI-GPNRC----ACVY 200
RC GG C QC+ C G + +G C++ CI G + C +C+
Sbjct: 179 RCRGGGPCKQ---QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 201 GFTGPQCERDYRTGP---------------CFTQVNNQM----CQGQLTGIVCTKTLCCA 241
+C+RD G C + ++N + CQ L C L C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 242 T--IGRAWGH------------PCEM------------CPAQPQPCRRGFIPNIRTGACQ 275
+ I A G+ PC + C C RG+ N C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 276 DVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
DVDEC C +G C+N+ GSF C C G+ ++ C D++EC PG +C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
NT+GSY C C G+ S DG C D + + C+QE QC C G
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQECANVYGSYQCYCRRG 468
Score = 89.0 bits (219), Expect = 6e-17
Identities = 98/306 (32%), Positives = 129/306 (42%), Gaps = 76/306 (24%)
Query: 114 ICRNSCGDGFCSRPNMCTCSSGQISSTCGSK-SIQQC---SVRCMNGGTCADDH----CQ 165
IC+N+ G C RP + C SG I G+ I +C S C G TC + CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 166 -----CQKGYI----GTYCGQ-----PVCENGCQNGGRCI---GPNRCACVYGFTGPQCE 208
C +GY GT C P E C G RC+ G RC C G+
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEP-CGKGHRCVNSPGSFRCECKTGY------ 388
Query: 209 RDYRTGPCFTQVNNQMCQ---GQLTGIVCTKTL----CCATIG---RAWGHPCE---MCP 255
Y G V+ CQ G+L G C TL C ++G G CE C
Sbjct: 389 --YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 256 AQPQP-------------CRRGF-IPNIRTGACQDVDECQAIPG--ICQGGNCINTVGSF 299
+ P CRRG+ + ++ C+D+DEC G IC CIN GSF
Sbjct: 447 SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSF 505
Query: 300 ECRCP-AGHKQSETTQKCEDIDECSIIPGI--CETGE-CSNTVGSYFCV---CPRGYVTS 352
+C CP +G++ + + C+DIDEC + GI C E C N G + C+ CP Y S
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCLAFECPENYRRS 563
Query: 353 TDGSRC 358
+RC
Sbjct: 564 A-ATRC 568
Score = 68.9 bits (167), Expect = 7e-11
Identities = 87/372 (23%), Positives = 142/372 (38%), Gaps = 83/372 (22%)
Query: 2410 CCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
CC DG R HQ + C LP Y T+ + EC+++ C C + +
Sbjct: 36 CCADGHRMATHQKD-CSLP--------------YATESK---ECRMVQEQC----CHSQL 73
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPR-GYVLQEDGK 2528
C T IS + + D C+ +P N + T C C G Q G+
Sbjct: 74 EELHC------ATGISLAN--EQDRCA-TPHGDNASLEATFVKRCCHCCLLGRAAQAQGQ 124
Query: 2529 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGIC 2588
+C+ + + G+ C C+ + E G G
Sbjct: 125 SCE----------------YSLMVGYQCG-----QVFRACCVKSQETGDLDV-----GGL 158
Query: 2589 QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
Q T E ++ + LN D C G C+ C++ C C GY
Sbjct: 159 QETDKIIEVEEEQ----EDPYLN----DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSD 210
Query: 2649 WNQCVDENEC-SNPNACG-SASCYNTLGSYKC----ACPSGFSFDQFSSACHDVNECSSS 2702
C D NEC + ++C SC NT+GS++C +C +G+ + ++C D++EC S
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESG 269
Query: 2703 KNPC--NYGCSNTEGGYLC----GCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENA 2756
+ C ++ C NT G + C C G+ + G+C+ N+ +S +
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCID---INECLSISAPCPIG-HTC 325
Query: 2757 LSPEACYECKIN 2768
++ E Y C+ N
Sbjct: 326 INTEGSYTCQKN 337
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 234 bits (596), Expect = 1e-60
Identities = 142/427 (33%), Positives = 210/427 (49%), Gaps = 48/427 (11%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCD----C 1185
C +T C CF GY+ +C D++EC CR G +C+NT GSF+C C
Sbjct: 190 CRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMIGTYQC----SCNPGYQATPDRQG- 1239
G+EL+ C DI+EC + C + C N +G+++C C G+ D G
Sbjct: 249 GTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALGN 305
Query: 1240 CTDIDECMIMNGGCDT--QCTNSEGSYEC-----SCSEGYALMPDGRSCADIDECENNPD 1292
C DI+EC+ ++ C C N+EGSY C +C GY L +G C D+DEC +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 1293 ICDGG-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICH 1351
C G +C N PG +RC C G+ + C+DVNEC +CENT GS++C
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW---IGNGIKCID 1408
C +G+ + C D++EC + C N+ GS++C CR G+ +G+ C D
Sbjct: 426 CSVGFRLSVDGRSCEDINECS----SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 1409 LDECS--NGTHQCSINAQCVNTPGSYRCAC-SEGF--TGDGFTCSDVDECAENINLCE-N 1462
+DEC+ G H CS +C+N PGS++C+C S G+ +G C D+DEC I+ C N
Sbjct: 482 IDECALPTGGHICSY--RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1463 GQCLNVPGAYRC---ECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
C N+ G +RC EC P + RS + + + +C P C+ D
Sbjct: 540 ETCFNIQGGFRCLAFEC-----PENYRRSAATLQQEKTDTVRCIKSCR--PNDVTCVFDP 592
Query: 1520 GYELDRT 1526
+ + T
Sbjct: 593 VHTISHT 599
Score = 225 bits (574), Expect = 4e-58
Identities = 149/446 (33%), Positives = 200/446 (44%), Gaps = 72/446 (16%)
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEP-GPMMNCEDINECAQNPLLCAF--RCMNT 2271
D C G PC C + C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2272 FGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----C 2323
GS+ C +C GY L ED CKD+DEC G+H+C +C+N +G+F C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLP-DFICQNTLGSFRCRPKLQC 294
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGR-CVNIIGSYRCE-----CNEGFQSSSSGTE 2377
G + G C+D NEC + C G C+N GSY C+ C G+ + GT
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2378 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2437
C+D + +E C G GH+C PG+ + C
Sbjct: 354 CVDVDE--------------------CAPPAEPC-----GKGHRC--VNSPGSFR----C 382
Query: 2438 PHGPGYTTDGR-----DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL 2492
GY DG D++EC+ P +C NT+GS+ C C VG+ + G SC D+
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2493 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE-DGKTCKDLDEC--QTKQHNCQFLCVN 2549
+ECS S PC+ C N GSYQC C RGY L + DG TC+D+DEC T H C + C+N
Sbjct: 443 NECSSS--PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 2550 TLGGFTCKCPPG---FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC---ECQRGF 2603
G F C CP + C D +EC + C C N G F C EC +
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 2604 SLDATGLNCEDVDECDGNHRCQHGCQ 2629
A L E D RC C+
Sbjct: 561 RRSAATLQQEKTDTV----RCIKSCR 582
Score = 211 bits (536), Expect = 1e-53
Identities = 145/414 (35%), Positives = 202/414 (48%), Gaps = 62/414 (14%)
Query: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGR-CFNEIGSFKC 1999
PC C++T C C+ G++L + C D++EC + CR G C N +GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITG-SHSCRLGESCINTVGSFRC 242
Query: 2000 L----CNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCI----CPPGY-EV 2049
C GYELT D +C D +EC + +C P CQN GSFRC C G+ +
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 2050 KSENCIDINECDEDPNICLFG-SCTNTPGGFQCL-----CPPGFVLSDNGRRCFDTRQSF 2103
NCIDINEC C G +C NT G + C C G+ L++ G RC D +
Sbjct: 302 ALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE-- 359
Query: 2104 CFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
C+ P A+ C G G C P +F+ C G+
Sbjct: 360 ---------CAPP-------AEPC-------GKGHRCVNSPG----SFRCECKTGY-YFD 391
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
+ DVNEC PG +C NT GS+ C C +G+ L G C D +ECS +PC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPC 450
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGPM--MNCEDINECA--QNPLLCAFRCMNTFGSYECTC 2279
C NV GS++C C G++ + + CEDI+ECA +C++RC+N GS++C+C
Sbjct: 451 SQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSC 509
Query: 2280 P-IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMAR 2329
P GY L + + C+D+DEC G+H+C S C N+ G F C+ CP R
Sbjct: 510 PSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (528), Expect = 9e-53
Identities = 177/614 (28%), Positives = 242/614 (39%), Gaps = 122/614 (19%)
Query: 1166 PLLCRGGTC-----VNTEGSFQCDCPLGHELSPSREDC-----VDINECSLSDNLCRNGK 1215
PLL GG V+ + + C GH ++ ++DC + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG-GCDTQCTNSEGSYECSCSEGYAL 1274
C + + C+ DR C +G + T + C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDR--------CATPHGDNASLEATFVKRCCHC-CLLGRAA 119
Query: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD---------GFMASMDMKTCID 1325
G+SC + G QC + +R C G + D ++
Sbjct: 120 QAQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVE 168
Query: 1326 VNECD--LNSNICMFG-----ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
+ D LN C G +C +T +C C +GY + C DV+EC G+H+C
Sbjct: 169 EEQEDPYLNDR-CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1379 DMHASCLNIPGSFKC----SCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ SC+N GSF+C SC G+ + C D+DEC +G H C + C NT GS+R
Sbjct: 228 RLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 1434 C----ACSEGFTGDGF-TCSDVDECAENINLCENGQ-CLNVPGAYRCE-----CEMGFTP 1482
C C GF D C D++EC C G C+N G+Y C+ C G+
Sbjct: 288 CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 1483 ASDSRSCQDIDECS-FQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-P 1539
+ C D+DEC+ C G C N PG F C C GY D C D++EC P
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP 407
Query: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
C NT G Y C+C F+L+ G C D + C S C+ E
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INEC---------SSSPCSQECAN 456
Query: 1600 GVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
C C G Y L + + EDIDEC
Sbjct: 457 VYGSYQCYCRRG------------------YQL--------SDVDGVTCEDIDEC----A 486
Query: 1660 LCQGGN-----CINTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTL 1712
L GG+ CIN GSFQC CP GY L+ + R C+DIDEC C TC+N
Sbjct: 487 LPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQ 546
Query: 1713 GNYTCI---CPPEY 1723
G + C+ CP Y
Sbjct: 547 GGFRCLAFECPENY 560
Score = 204 bits (518), Expect = 1e-51
Identities = 120/284 (42%), Positives = 143/284 (50%), Gaps = 25/284 (8%)
Query: 2464 QCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY--ICKNTEGSYQC----SC 2517
QC +T C C VGY G SC D++EC C C NT GS++C SC
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 2518 PRGYVLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTCK----CPPGFTQHHTA-CI 2570
GY L ED +CKD+DEC++ HNC F+C NTLG F C+ C GF Q CI
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCI 307
Query: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCE-----CQRGFSLDATGLNCEDVDEC-DGNHRC 2624
D NEC S + C C NT GS++C+ C RG+ L+ G C DVDEC C
Sbjct: 308 DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Query: 2625 Q--HGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACP 2681
H C N G +RC C GY CVD NEC P C NTLGSY C+C
Sbjct: 368 GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCS 427
Query: 2682 SGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
GF +C D+NECSSS PC+ C+N G Y C C GY
Sbjct: 428 VGFRLSVDGRSCEDINECSSS--PCSQECANVYGSYQCYCRRGY 469
Score = 196 bits (497), Expect = 4e-49
Identities = 123/364 (33%), Positives = 169/364 (46%), Gaps = 48/364 (13%)
Query: 2412 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT--TDG---RDIDECKVMPNLCTNGQ-C 2465
C GG QC + +C GY +DG D++EC + C G+ C
Sbjct: 180 CRGGGPCKQQCR------DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESC 233
Query: 2466 INTMGSFRC----FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC---- 2515
INT+GSFRC C GY SC D+DEC C ++IC+NT GS++C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCK-----CPPGF--TQHH 2566
C G++ G C D++EC + C C+NT G +TC+ C G+ +
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 2567 TACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG--NHRC 2624
T C+D +EC CG C N+PGSF CEC+ G+ D C DV+EC C
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 2625 QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 2684
H C+N LG Y C C G+ C D NECS+ + C S C N GSY+C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-SPC-SQECANVYGSYQCYCRRGY 469
Query: 2685 SFDQFSSA-CHDVNECS--SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG--------HC 2733
C D++EC+ + + C+Y C N G + C CP YR+ C
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2734 VSGM 2737
V+G+
Sbjct: 530 VTGI 533
Score = 194 bits (493), Expect = 1e-48
Identities = 140/448 (31%), Positives = 201/448 (44%), Gaps = 70/448 (15%)
Query: 1803 TGKAVDIDECKEIPGI---CANG-----VCINQIGSFRCECPTGFSYNDLLLVCEDIDEC 1854
T K ++++E +E P + C G C + C C G+ + CED++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 1855 SNGDNLCQRNADCINSPGSYRCE----CAAGFKLSPNGACVDRNECLE-IPNVCSHGLCV 1909
G + C+ CIN+ GS+RC+ C G++L+ + +C D +EC I N +C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 1910 DLQGSYQCI----CHNGFKASQDQT-MCMDVDECER--HPCGNG-TCKNTVGSYNCL--- 1958
+ GS++C C +GF QD C+D++EC PC G TC NT GSY C
Sbjct: 281 NTLGSFRCRPKLQCKSGF--IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 1959 --CYPGFELTHNND-CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 2015
C G+ L C+D+DEC+ + RC N GSF+C C GY + C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCT 2073
D NEC PG C+N GS+ C C G+ V +C DINEC P C
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP---CSQECA 455
Query: 2074 NTPGGFQCLCPPGFVLSD-NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMP 2132
N G +QC C G+ LSD +G C D +C++P + +C +P
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDI-----------DECALPTGGHICSYRCI--NIP 502
Query: 2133 GEGWGDPCELCPKDDEVAFQDLCP-YGHGTVPSLHDTREDVNECLESPGICS-NGQCINT 2190
G +FQ CP G+ P+ + +D++EC+ CS N C N
Sbjct: 503 G----------------SFQCSCPSSGYRLAPNGRNC-QDIDECVTGIHNCSINETCFNI 545
Query: 2191 DGSFRC---ECPMGYNLDYTGVRCVDTD 2215
G FRC ECP Y ++ TD
Sbjct: 546 QGGFRCLAFECPENYRRSAATLQQEKTD 573
Score = 194 bits (493), Expect = 1e-48
Identities = 135/401 (33%), Positives = 185/401 (46%), Gaps = 58/401 (14%)
Query: 970 RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAV 1029
+C ++ C C G L G C D+ +ECI ++C V
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDV-----------NECITGSHSCRLGESCINTV 237
Query: 1030 GAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK- 1088
G+ C+ GT G LT KDI+EC++ C
Sbjct: 238 GSF---RCQRDSSCGT----------------GYELTEDNSCKDIDECESGIHNCLPDFI 278
Query: 1089 CRNTIGSFKCR----CNSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFECE-- 1141
C+NT+GSF+CR C SGF D NC DI+EC C G C+NT GS+ C+
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 1142 ---CFEGY---ESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPS 1194
C GY E G C+D+DEC C +G CVN+ GSF+C+C G+
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD 1254
CVD+NEC KC N +G+Y CSC+ G++ + D + C DI+EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCS 451
Query: 1255 TQCTNSEGSYECSCSEGYALMP-DGRSCADIDEC--ENNPDICDGGQCTNIPGEYRCLC- 1310
+C N GSY+C C GY L DG +C DIDEC IC +C NIPG ++C C
Sbjct: 452 QECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCP 510
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFIC 1350
G+ + + + C D++EC + C E C N +G F C
Sbjct: 511 SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 192 bits (489), Expect = 3e-48
Identities = 137/457 (29%), Positives = 196/457 (42%), Gaps = 69/457 (15%)
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKP 2346
E+++ L++ G C+ + C++ +C C G DG C D NEC T
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQ---CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS 224
Query: 2347 GICENGR-CVNIIGSYRCE----CNEGFQ-SSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
C G C+N +GS+RC+ C G++ + + + +D + + ICQ
Sbjct: 225 HSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLG 284
Query: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR----DIDECKVM 2456
S K +C G+ D DI+EC +
Sbjct: 285 SFRCRPKLQC-----------------------------KSGFIQDALGNCIDINECLSI 315
Query: 2457 PNLCTNGQ-CINTMGSFRCF-----CKVGYTTDISGTSCIDLDECSQSPKPCN--YICKN 2508
C G CINT GS+ C C GY + GT C+D+DEC+ +PC + C N
Sbjct: 316 SAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 2509 TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN-CQFLCVNTLGGFTCKCPPGF--TQH 2565
+ GS++C C GY + C D++ECQ C C NTLG + C C GF +
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVD 435
Query: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL-DATGLNCEDVDEC---DGN 2621
+C D NEC S P C + C N GS+ C C+RG+ L D G+ CED+DEC G
Sbjct: 436 GRSCEDINECSSSP--CSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGG 491
Query: 2622 HRCQHGCQNILGGYRCGCP-QGYIQHYQWNQCVDENECSN--PNACGSASCYNTLGSYKC 2678
H C + C NI G ++C CP GY C D +EC N + +C+N G ++C
Sbjct: 492 HICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Query: 2679 ---ACPSGF--SFDQFSSACHDVNECSSSKNPCNYGC 2710
CP + S D C S P + C
Sbjct: 552 LAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 187 bits (475), Expect = 1e-46
Identities = 135/405 (33%), Positives = 183/405 (45%), Gaps = 73/405 (18%)
Query: 493 QTIDICKHHANLCLNGR-CIPTVSSYRCE----CNMGYKQDANGDCIDVDECTS---NPC 544
+ ++ C ++ C G CI TV S+RC+ C GY+ + C D+DEC S N
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 545 TNGDCVNTPGSYYCK----CHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTDGSFQ 599
+ C NT GS+ C+ C +GF + CIDI+EC+ C G C+NT+GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 600 C-----ICNAGFELTTDGKNCVDHDECT-TTNMCLNG-MCINEDGSFKCICKPGFVLAPN 652
C C G+ L +G CVD DEC C G C+N GSF+C CK G+
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 653 GRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
R C DV+ECQ PG C N+ GS+ C C G + +DGR C D
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI----------- 442
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT-VDG---R 767
+EC PC A + C G ++ VDG
Sbjct: 443 --------------NECS--------SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 768 DINECALDP--DICANGICENLRGSYRCNC-NSGYEPDASGRNCIDIDECLVNRLLCD-N 823
DI+ECAL IC+ C N+ GS++C+C +SGY +GRNC DIDEC+ C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 824 GLCRNTPGSYSC---TCPPGY------VFRTETETCEDINECESN 859
C N G + C CP Y + + +T+T I C N
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPN 584
Score = 170 bits (430), Expect = 2e-41
Identities = 135/409 (33%), Positives = 177/409 (43%), Gaps = 73/409 (17%)
Query: 537 DECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTD 595
D C C +T C C G+Q +C D++ECI C+ G C+NT
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 596 GSFQC----ICNAGFELTTDGKNCVDHDECTT-TNMCL-NGMCINEDGSFKCI----CKP 645
GSF+C C G+ELT D +C D DEC + + CL + +C N GSF+C CK
Sbjct: 238 GSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 646 GFVLAPNGRYCTDVDECQTPGI-CMNGH-CINSEGSFRC-----DCPPGLAVGMDGRVCV 698
GF+ G C D++EC + C GH CIN+EGS+ C +C G + +G CV
Sbjct: 297 GFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 699 DTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSS 758
D EC G G C P E C +
Sbjct: 356 DV-------------------------DECAPPAEPCGKGHRCVNSPGSFRCE----CKT 386
Query: 759 GV---GITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL 815
G GI+ D+NEC P CEN GSY C+C+ G+ GR+C DI+EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 816 VNRLLCDNGLCRNTPGSYSCTCPPGY-VFRTETETCEDINEC---ESNPCVNGACRNNLG 871
+ + C N GSY C C GY + + TCEDI+EC + C N G
Sbjct: 447 SSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 872 SFNCEC-SPGSKLSSTGLICID-----------SLKGTCWLNIQDS-RC 907
SF C C S G +L+ G C D S+ TC+ NIQ RC
Sbjct: 504 SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRC 551
Score = 164 bits (416), Expect = 9e-40
Identities = 135/444 (30%), Positives = 187/444 (42%), Gaps = 91/444 (20%)
Query: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHC----IC 1517
QC + C C +G+ SD SC+D++EC + + C G +C N G F C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1518 DDGYELDRTGGNCTDIDECADPI-NCV-NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
GYEL +C DIDEC I NC+ + +C NT G + C P Q G + +
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQCKS---GFIQDA 302
Query: 1576 VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
+GNC + N + + S C +G TC +N+ YT
Sbjct: 303 LGNC-----------IDINECLSI-----SAPCPIG-------HTC--INTEGSYTCQKN 337
Query: 1636 ----GEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
G G+ N D+DEC C +G C+N+ GSF+CEC GYY +R+C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 1691 EDIDECFAHPG-VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
D++EC +PG +CG C NTLG+Y C C + G +C D+ + + + C
Sbjct: 398 VDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC------SSSPC 450
Query: 1750 ENELPFNVTKRMCCCT--YNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 1807
E C C Y + CE
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCE------------------------------ 480
Query: 1808 DIDECKEIPG--ICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
DIDEC G IC+ CIN GSF+C CP +G+ C+DIDEC G + C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1865 ADCINSPGSYRC---ECAAGFKLS 1885
C N G +RC EC ++ S
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRS 563
Score = 148 bits (374), Expect = 7e-35
Identities = 176/638 (27%), Positives = 244/638 (38%), Gaps = 136/638 (21%)
Query: 592 VNTDGSFQCICNAGFELTTDGKNC-----VDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
V+ D + C G + T K+C + EC M C ++ C G
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKEC---RMVQEQCCHSQLEELHCAT--G 81
Query: 647 FVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF--RCD--CPPGLAVGMDGRVCVDTHM 702
LA + D C TP +G + E +F RC C G A G+ C + M
Sbjct: 82 ISLA------NEQDRCATP----HGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLM 131
Query: 703 RSTCYGGIKKGVCVRPFP------GAVTKSECCCA----------NPDYGFGEPCQPCPA 746
G + + CV+ G + +++ N G PC+
Sbjct: 132 VGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCR 191
Query: 747 KNSAEFHGLCSSGVGITVDG---RDINECALDPDICANG-ICENLRGSYRC----NCNSG 798
E C G + DG D+NEC C G C N GS+RC +C +G
Sbjct: 192 DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTG 251
Query: 799 YEPDASGRNCIDIDECLVNRLLC-DNGLCRNTPGSYSCT----CPPGYVFRTETETCEDI 853
YE +C DIDEC C + +C+NT GS+ C C G++ + C DI
Sbjct: 252 YEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI-QDALGNCIDI 309
Query: 854 NECES--NPCVNG-ACRNNLGSFNCE-----CSPGSKLSSTGLICIDSLKGTCWLNIQDS 905
NEC S PC G C N GS+ C+ C G L+ G C+D
Sbjct: 310 NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD------------- 356
Query: 906 RCEVNINGATLKSECCATLGAAWGSPCE-RCELDTACP-RGLARIKGVTCEDVNECEVFP 963
++ +E C SP RCE T G++R+ C DVNEC+ +P
Sbjct: 357 -----VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM----CVDVNECQRYP 407
Query: 964 GVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMD 1023
G +C N+ GS+ C C G L GR C DI +C EC +
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI--NECSSSPCSQECAN--------- 456
Query: 1024 ACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG- 1082
+G+ Y+ C RG ++ V +DI+EC G
Sbjct: 457 --------VYGS------------YQCYCRRGYQLSDVDGVTC-----EDIDECALPTGG 491
Query: 1083 -MCTYGKCRNTIGSFKCRC-NSGFALDMEERNCTDIDECRISPDLCG-SGICVNTPGSFE 1139
+C+Y +C N GSF+C C +SG+ L RNC DIDEC C + C N G F
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFR 550
Query: 1140 C---ECFEGY-ESGFMMMKNCMD----IDECERNPLLC 1169
C EC E Y S + + D I C N + C
Sbjct: 551 CLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTC 588
Score = 144 bits (363), Expect = 1e-33
Identities = 118/398 (29%), Positives = 172/398 (43%), Gaps = 86/398 (21%)
Query: 273 ACQDVDECQAIPGICQ-GGNCINTVGSFECR----CPAGHKQSETTQKCEDIDEC-SIIP 326
+C+DV+EC C+ G +CINTVGSF C+ C G++ +E C+DIDEC S I
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIH 271
Query: 327 GICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM 386
C NT+GS+ RC + C SG + Q+ G
Sbjct: 272 NCLPDFICQNTLGSF---------------RCRPKL--QCKSGFI-----QDALGN---- 305
Query: 387 QCCCEPGRCWGIGTIPEACPVRGS---EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFA 443
C + C I CP+ + E C +P
Sbjct: 306 --CIDINECLSISA---PCPIGHTCINTEGSYTCQKNVPN-------------------- 340
Query: 444 PSGNGNGYGPGGTGFIPI--------PGGNGF----SPGVGGAGVGAGGQGPIITGLTIL 491
G G GT + + P G G SPG G G++ +
Sbjct: 341 -CGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYY---FDGISRM 396
Query: 492 NQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCV 550
++ C+ + +C T+ SY C C++G++ +G C D++EC+S+PC+ +C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ-ECA 455
Query: 551 NTPGSYYCKCHAGFQRTPTK-QACIDIDECI--QNGVLCKNGRCVNTDGSFQCIC-NAGF 606
N GSY C C G+Q + C DIDEC G +C + RC+N GSFQC C ++G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGY 514
Query: 607 ELTTDGKNCVDHDECTT--TNMCLNGMCINEDGSFKCI 642
L +G+NC D DEC T N +N C N G F+C+
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 99.0 bits (245), Expect = 6e-20
Identities = 99/327 (30%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 97 CCPGWKTLPGG------NQCIV--------PICRNSCGDGFCSRPNMCTCSSGQISSTCG 142
C G++ L G N+CI C N+ G C R + C + +++
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG-TGYELTEDNS 259
Query: 143 SKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNG------GRCIGPNRC 196
K I +C N C D CQ +G++ +P + C++G G CI N C
Sbjct: 260 CKDIDECESGIHN---CLPDFI-CQNT-LGSFRCRPKLQ--CKSGFIQDALGNCIDINEC 312
Query: 197 A-----CVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLT--GIVCTKTLCCATIGRAWG- 248
C G T E Y C V N L G C CA G
Sbjct: 313 LSISAPCPIGHTCINTEGSYT---CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK 369
Query: 249 -HPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H C P + C+ G+ + + C DV+ECQ PG G C NT+GS+ C C G
Sbjct: 370 GHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVG 429
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY-VTSTDGSRC--IDQRT 363
+ S + CEDI+ECS P C EC+N GSY C C RGY ++ DG C ID+
Sbjct: 430 FRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 364 GMCFSGLVNGRCAQELPGRMTKMQCCC 390
+ + RC +PG QC C
Sbjct: 487 LPTGGHICSYRCI-NIPG---SFQCSC 509
Score = 94.4 bits (233), Expect = 2e-18
Identities = 81/299 (27%), Positives = 113/299 (37%), Gaps = 66/299 (22%)
Query: 152 RCMNGGTCADDHCQCQKGYIGTYC----GQPVCENG--CQNGGRCI-GPNRC----ACVY 200
RC GG C QC+ C G + +G C++ CI G + C +C+
Sbjct: 179 RCRGGGPCKQ---QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 201 GFTGPQCERDYRTGP---------------CFTQVNNQM----CQGQLTGIVCTKTLCCA 241
+C+RD G C + ++N + CQ L C L C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 242 T--IGRAWGH------------PCEM------------CPAQPQPCRRGFIPNIRTGACQ 275
+ I A G+ PC + C C RG+ N C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 276 DVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
DVDEC C +G C+N+ GSF C C G+ ++ C D++EC PG +C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
NT+GSY C C G+ S DG C D + + C+QE QC C G
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQECANVYGSYQCYCRRG 468
Score = 90.1 bits (222), Expect = 3e-17
Identities = 101/315 (32%), Positives = 131/315 (41%), Gaps = 83/315 (26%)
Query: 114 ICRNSCGDGFCSRPNMCTCSSGQISSTCGSK-SIQQC---SVRCMNGGTCADDH----CQ 165
IC+N+ G C RP + C SG I G+ I +C S C G TC + CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 166 -----CQKGYI----GTYCGQ-----PVCENGCQNGGRCI---GPNRCACVYGFTGPQCE 208
C +GY GT C P E C G RC+ G RC C G+
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEP-CGKGHRCVNSPGSFRCECKTGY------ 388
Query: 209 RDYRTGPCFTQVNNQMCQ---GQLTGIVCTKTL----CCATIG---RAWGHPCE---MCP 255
Y G V+ CQ G+L G C TL C ++G G CE C
Sbjct: 389 --YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 256 AQPQP-------------CRRGF-IPNIRTGACQDVDECQAIPG--ICQGGNCINTVGSF 299
+ P CRRG+ + ++ C+D+DEC G IC CIN GSF
Sbjct: 447 SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSF 505
Query: 300 ECRCP-AGHKQSETTQKCEDIDECSIIPGI--CETGE-CSNTVGSYFCV---CPRGYVTS 352
+C CP +G++ + + C+DIDEC + GI C E C N G + C+ CP Y S
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCLAFECPENYRRS 563
Query: 353 --------TDGSRCI 359
TD RCI
Sbjct: 564 AATLQQEKTDTVRCI 578
Score = 68.9 bits (167), Expect = 7e-11
Identities = 87/372 (23%), Positives = 142/372 (38%), Gaps = 83/372 (22%)
Query: 2410 CCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
CC DG R HQ + C LP Y T+ + EC+++ C C + +
Sbjct: 36 CCADGHRMATHQKD-CSLP--------------YATESK---ECRMVQEQC----CHSQL 73
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPR-GYVLQEDGK 2528
C T IS + + D C+ +P N + T C C G Q G+
Sbjct: 74 EELHC------ATGISLAN--EQDRCA-TPHGDNASLEATFVKRCCHCCLLGRAAQAQGQ 124
Query: 2529 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGIC 2588
+C+ + + G+ C C+ + E G G
Sbjct: 125 SCE----------------YSLMVGYQCG-----QVFRACCVKSQETGDLDV-----GGL 158
Query: 2589 QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
Q T E ++ + LN D C G C+ C++ C C GY
Sbjct: 159 QETDKIIEVEEEQ----EDPYLN----DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSD 210
Query: 2649 WNQCVDENEC-SNPNACG-SASCYNTLGSYKC----ACPSGFSFDQFSSACHDVNECSSS 2702
C D NEC + ++C SC NT+GS++C +C +G+ + ++C D++EC S
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESG 269
Query: 2703 KNPC--NYGCSNTEGGYLC----GCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENA 2756
+ C ++ C NT G + C C G+ + G+C+ N+ +S +
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCID---INECLSISAPCPIG-HTC 325
Query: 2757 LSPEACYECKIN 2768
++ E Y C+ N
Sbjct: 326 INTEGSYTCQKN 337
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 233 bits (595), Expect = 2e-60
Identities = 243/919 (26%), Positives = 361/919 (39%), Gaps = 218/919 (23%)
Query: 1301 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 1360
N ++ L + G +A ++++ + CD N + + F H +
Sbjct: 173 NPEDRWKSLHFSGHVAHLELQIRV---RCDENYYSATCNKFCRPRNDFFGHYTCD---QY 226
Query: 1361 GTTGCTDV---DECE--IGAHNCDM-HASCLNIPGSFKCSCREGWIGNGI-KCIDLDECS 1413
G C D EC+ + C++ H C +PG +C C GW G +C+ C
Sbjct: 227 GNKACMDGWMGKECKEAVCKQGCNLLHGGC-TVPG--ECRCSYGWQGRFCDECVPYPGCV 283
Query: 1414 NGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS-DVDECAENINLCENGQCLNV-PGA 1471
+G+ CV ++C C + G C D++ C + G C+N P
Sbjct: 284 HGS--------CVEP---WQCNCETNW--GGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 1472 YRCECEMGFTPASDSRSCQDIDECSFQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNC 1530
YRC C G++ R+C+ + N C G +C+ +P F C C G+ +G C
Sbjct: 331 YRCTCPDGYS----GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPTC 382
Query: 1531 T-DIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 1589
DIDECA G CV+ +EC CP + G C
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQW----VGATC------------------ 420
Query: 1590 SLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILE 1649
++ V R C G C+ VN Y +CP G G R +
Sbjct: 421 ------QLDVNDCRGQC------QHGGTCKDL--VNG--YQCVCPRGFGGRHCEL----- 459
Query: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGT- 1707
+ DEC P GG C + F C CPQG+ +CE D+D C P C G
Sbjct: 460 ERDECASSP-CHSGGLCEDLADGFHCHCPQGF----SGPLCEVDVDLC--EPSPCRNGAR 512
Query: 1708 CYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYN 1767
CYN G+Y C CP ++ GG NC
Sbjct: 513 CYNLEGDYYCACPDDF----GGKNC----------------------------------- 533
Query: 1768 VGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV---- 1823
+ P EPC PG A C I G D G +PG A+GV
Sbjct: 534 -----SVPREPC--PGGA-----CRVIDGCGSDAGPG----------MPGTAASGVCGPH 571
Query: 1824 --CINQI-GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAA 1880
C++Q G+F C C +GF+ E+ID+C C+ CI+ ++RC C +
Sbjct: 572 GRCVSQPGGNFSCICDSGFTGT---YCHENIDDCLG--QPCRNGGTCIDEVDAFRCFCPS 626
Query: 1881 GFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE 1939
G++ G D N +P+ C S G C DL + C C +G+K +T +C+
Sbjct: 627 GWE----GELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKG---KTCHSREFQCD 679
Query: 1940 RHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFK 1998
+ C N GTC ++ ++ C C PG++ + C S G C SF
Sbjct: 680 AYTCSNGGTCYDSGDTFRCACPPGWK---GSTCAVAKNSSCLPNPCVNGGTCVGSGASFS 736
Query: 1999 CLCNEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC-ID 2056
C+C +G+E G+ C +TN+C LP + G C + FRC C PG+ +C I+
Sbjct: 737 CICRDGWE----GRTCTHNTNDCNPLP-CYNGGICVDGVNWFRCECAPGF--AGPDCRIN 789
Query: 2057 INECDEDPNICLFG-SCTNTPGGFQCLCPPGFV------LSDNGRRCFDTRQSFCFTNFE 2109
I+EC P C +G +C + G++C CPPG + GR C+ F +
Sbjct: 790 IDECQSSP--CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSW 847
Query: 2110 NGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTR 2169
C+ + + + CSK+ GW PC L + + ++ Q CP G
Sbjct: 848 VEDCNSCRCLDGRRD---CSKV-WCGW-KPCLLAGQPEALSAQ--CPLG----------- 889
Query: 2170 EDVNECLE-SPGICSNGQC 2187
CLE +PG C C
Sbjct: 890 ---QRCLEKAPGQCLRPPC 905
Score = 191 bits (486), Expect = 7e-48
Identities = 182/660 (27%), Positives = 260/660 (39%), Gaps = 111/660 (16%)
Query: 695 RVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYG-FGEPCQPCPAKNSAEFH 753
+ C+D M C + K C G EC C+ G F + C P P H
Sbjct: 229 KACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGC----VH 284
Query: 754 GLC---------SSGVGITVDGRDINECALDPDICANGICENLR-GSYRCNCNSGYEPDA 803
G C ++ G+ D +D+N C G C N YRC C GY
Sbjct: 285 GSCVEPWQCNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY---- 339
Query: 804 SGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPC- 861
SGRNC + + + G C P + C CP G+ TC DI+EC SNPC
Sbjct: 340 SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPTCALDIDECASNPCA 395
Query: 862 VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING-------- 913
G C + + F C C P + +T + ++ +G C C+ +NG
Sbjct: 396 AGGTCVDQVDGFECIC-PEQWVGATCQLDVNDCRGQCQ---HGGTCKDLVNGYQCVCPRG 451
Query: 914 -----ATLKSECCATLGAAWGSPCERCE--LDTACPRGLARIKGVTCE-DVNECEVFPGV 965
L+ + CA+ G CE CP+G + G CE DV+ CE P
Sbjct: 452 FGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFS---GPLCEVDVDLCE--PSP 506
Query: 966 CPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDA 1024
C NG RC N +G ++C CP+ D G+ C R P PG
Sbjct: 507 CRNGARCYNLEGDYYCACPD----DFGGKNCSVPR--------------EPCPGG----- 543
Query: 1025 CCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRG--------DVLTGRPFYKDINE 1076
C V G++ PGT P G + G TG +++I++
Sbjct: 544 -ACRVIDGCGSDAGP-GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDD 601
Query: 1077 CKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS-GICVNTP 1135
C P G C + + +F+C C SG+ ++ + N D PD C S G C +
Sbjct: 602 CLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPND-----CLPDPCHSRGRCYDLV 655
Query: 1136 GSFECECFEGYESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPS 1194
F C C +G++ K C E + + C GGTC ++ +F+C CP G + S
Sbjct: 656 NDFYCACDDGWKG-----KTCHS-REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGS-- 707
Query: 1195 REDCVDINECSLSDNLCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC 1253
C S N C N G CV ++ C C G++ D + NGG
Sbjct: 708 --TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 765
Query: 1254 DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDG 1313
C + + C C+ G+A PD R +IDEC+++P G C + YRC C G
Sbjct: 766 ---CVDGVNWFRCECAPGFA-GPDCR--INIDECQSSP-CAYGATCVDEINGYRCSCPPG 818
Score = 190 bits (483), Expect = 2e-47
Identities = 161/599 (26%), Positives = 238/599 (39%), Gaps = 119/599 (19%)
Query: 2170 EDVNECLESPGICSNGQCINTD-GSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG-T 2227
+D+N C + G CIN + +RC CP GY+ G C + NPC NG +
Sbjct: 306 KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNPCANGGS 361
Query: 2228 CTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCP---IGYA 2284
C V FEC+C G+ GP DI+ECA NP C++ +EC CP +G
Sbjct: 362 CHEVPSGFECHCPSGWS-GPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWVGAT 419
Query: 2285 LREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECR 2343
+ D C+ C+ G CK+L+ + C+CP G G C ++ +EC
Sbjct: 420 CQLDVNDCRG---------QCQHGGT-CKDLVNGYQCVCPRGFG----GRHCELERDECA 465
Query: 2344 TKPGICENGR-CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSR 2402
+ P C +G C ++ + C C +GF SG C + LC C+ +
Sbjct: 466 SSP--CHSGGLCEDLADGFHCHCPQGF----SGPLC-EVDVDLCEPSP----CRNGARCY 514
Query: 2403 NLVTKSECCCD---GGRGWGHQCELCP-----------------LPGTAQYKKICPHGPG 2442
NL C C GG+ E CP +PGTA PHG
Sbjct: 515 NLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRC 574
Query: 2443 YTTDG-----------------RDIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDI 2484
+ G +ID+C P C NG CI+ + +FRCFC G+ ++
Sbjct: 575 VSQPGGNFSCICDSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGWEGEL 632
Query: 2485 SGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLD-ECQTKQHNC 2543
T+ D C P C + + C+C G+ GKTC + +C +
Sbjct: 633 CDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGW----KGKTCHSREFQCDAYTCSN 685
Query: 2544 QFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGF 2603
C ++ F C CPPG+ A N+ C P + G G C + SFSC C+ G+
Sbjct: 686 GGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNG--GTCVGSGASFSCICRDGW 743
Query: 2604 SLDATGLNCEDVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC-VDENECSN 2660
N D + C +G C + + +RC C G+ C ++ +EC +
Sbjct: 744 EGRTCTHNTNDCNPLP----CYNGGICVDGVNWFRCECAPGFAGP----DCRINIDECQS 795
Query: 2661 PNACGSASCYNTLGSYKCACPSGFS--------------------FDQFSSACHDVNEC 2699
A+C + + Y+C+CP G + F SS D N C
Sbjct: 796 SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSC 854
Score = 184 bits (468), Expect = 8e-46
Identities = 193/734 (26%), Positives = 277/734 (37%), Gaps = 155/734 (21%)
Query: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD-M 1735
C + YY + + C ++ F H TC + GN C M G C + +
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHY------TC-DQYGNKAC------MDGWMGKECKEAV 244
Query: 1736 RKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEP--------CPTPGTADF 1787
K C + G T E C C+Y + C P C P +
Sbjct: 245 CKQGCNLLHGGCTVPGE---------CRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNC 295
Query: 1788 KTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN-QIGSFRCECPTGFSYNDLLL 1846
+T G G D D++ C G CIN + +RC CP G+S +
Sbjct: 296 ETNWG---GLLCD------KDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRN--- 343
Query: 1847 VCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHG 1906
CE + N C C P + C C +G+ S +D +EC P + G
Sbjct: 344 -CEKAEHACTS-NPCANGGSCHEVPSGFECHCPSGW--SGPTCALDIDECASNP-CAAGG 398
Query: 1907 LCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELT 1966
CVD ++CIC + + Q +DV++C GTCK+ V Y C+C GF
Sbjct: 399 TCVDQVDGFECICPEQWVGATCQ---LDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGR 455
Query: 1967 HNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALP 2024
H L+ DEC+S C + G C + F C C +G+ G C +D + C P
Sbjct: 456 HCE--LERDECAS---SPCHSGGLCEDLADGFHCHCPQGF----SGPLCEVDVDLCE--P 504
Query: 2025 GSCSPGT-CQNLEGSFRCICPPGYEVKSEN----------CIDINECDED---------- 2063
C G C NLEG + C CP + K+ + C I+ C D
Sbjct: 505 SPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA 564
Query: 2064 PNIC-LFGSCTNTPGG-FQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNT 2121
+C G C + PGG F C+C GF ++C N ++
Sbjct: 565 SGVCGPHGRCVSQPGGNFSCICDSGFT------------GTYCHENIDD----------- 601
Query: 2122 TKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGI 2181
C P G C D+ AF+ CP G L DT + N+CL P
Sbjct: 602 ------CLGQPCRN-GGTC----IDEVDAFRCFCP--SGWEGELCDT--NPNDCLPDP-C 645
Query: 2182 CSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTD-ECSIGNPCGNGTCTNVIGSFECNCN 2240
S G+C + F C C G+ G C + +C GTC + +F C C
Sbjct: 646 HSRGRCYDLVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP 701
Query: 2241 EGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAE 2300
G++ G + C NP + C+ + S+ C C G+ R C
Sbjct: 702 PGWK-GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR----------TCTH 750
Query: 2301 GLHDCES----RGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENG-RC 2354
+DC G +C + + F C C PG A G C ++ +EC++ P C G C
Sbjct: 751 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFA----GPDCRINIDECQSSP--CAYGATC 804
Query: 2355 VNIIGSYRCECNEG 2368
V+ I YRC C G
Sbjct: 805 VDEINGYRCSCPPG 818
Score = 177 bits (450), Expect = 1e-43
Identities = 177/673 (26%), Positives = 260/673 (38%), Gaps = 139/673 (20%)
Query: 85 GPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCG--DGFCSRPNMCTCSSGQISSTCG 142
G C + C GW G +C +C+ C G C+ P C CS G C
Sbjct: 219 GHYTCDQYGNKACMDGWM----GKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC- 273
Query: 143 SKSIQQCSVR--CMNGGTCADDHCQCQKGYIGTYCGQPVCENG----CQNGGRCIGPN-- 194
+C C++G C C+ + G C + + G C NGG CI
Sbjct: 274 ----DECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329
Query: 195 --RCACVYGFTGPQCERDYR---TGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGH 249
RC C G++G CE+ + PC N C +G C C + W
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPC---ANGGSCHEVPSGFECH----CPS---GWSG 379
Query: 250 PCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQ 309
P D+DEC + P GG C++ V FEC CP +
Sbjct: 380 PT---------------------CALDIDECASNP-CAAGGTCVDQVDGFECICP----E 413
Query: 310 SETTQKCE-DIDECSIIPGICETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQR----T 363
C+ D+++C G C+ G C + V Y CVCPRG+ G C +R +
Sbjct: 414 QWVGATCQLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF----GGRHCELERDECAS 466
Query: 364 GMCFSG-----LVNG---RCAQELPGRMTKMQC-CCEPG------RCWGI-GTIPEACPV 407
C SG L +G C Q G + ++ CEP RC+ + G ACP
Sbjct: 467 SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP- 525
Query: 408 RGSEEYRRLCMDGLPMGGIPGSAGSRPGGTG---GNGFAPSGNGNGYGPGGTGFIPIPGG 464
+ + C +P PG A G G G G + GP G + PGG
Sbjct: 526 --DDFGGKNC--SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR-CVSQPGG 580
Query: 465 N-------GFSPGVGGAGVGAGGQGPIITGLTILNQTI------------DICKHHANLC 505
N GF+ + P G T +++ ++C + N C
Sbjct: 581 NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC 640
Query: 506 L------NGRCIPTVSSYRCECNMGYKQDANGDCIDVD-ECTSNPCTNGD-CVNTPGSYY 557
L GRC V+ + C C+ G+K C + +C + C+NG C ++ ++
Sbjct: 641 LPDPCHSRGRCYDLVNDFYCACDDGWKGKT---CHSREFQCDAYTCSNGGTCYDSGDTFR 697
Query: 558 CKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVD 617
C C G++ + A C+ N + G CV + SF CIC G+E G+ C
Sbjct: 698 CACPPGWKGSTC--AVAKNSSCLPNPCV-NGGTCVGSGASFSCICRDGWE----GRTCTH 750
Query: 618 HDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINS 676
+ C NG +C++ F+C C PGF P+ R ++DECQ+ C++
Sbjct: 751 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFA-GPDCRI--NIDECQSSPCAYGATCVDE 807
Query: 677 EGSFRCDCPPGLA 689
+RC CPPG A
Sbjct: 808 INGYRCSCPPGRA 820
Score = 176 bits (447), Expect = 2e-43
Identities = 190/706 (26%), Positives = 272/706 (38%), Gaps = 157/706 (22%)
Query: 1910 DLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYN----CLCYPGFEL 1965
D G Y C + G KA D M EC+ C G C G C C G++
Sbjct: 216 DFFGHYTCDQY-GNKACMDGWMGK---ECKEAVCKQG-CNLLHGGCTVPGECRCSYGWQ- 269
Query: 1966 THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI-DTNECVALP 2024
C DEC + G C +G C + ++C C + G C D N C +
Sbjct: 270 --GRFC---DECVPYPG--CVHGSC---VEPWQCNCETNW----GGLLCDKDLNYCGSHH 315
Query: 2025 GSCSPGTCQNLE-GSFRCICPPGYE----VKSENCIDINECDEDPNICLFGSCTNTPGGF 2079
+ GTC N E +RC CP GY K+E+ N C GSC P GF
Sbjct: 316 PCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANG------GSCHEVPSGF 369
Query: 2080 QCLCPPGFVLSDNGRRC-FDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGD 2138
+C CP G+ +G C D + G C +C C P + G
Sbjct: 370 ECHCPSGW----SGPTCALDIDECASNPCAAGGTC----VDQVDGFECIC---PEQWVGA 418
Query: 2139 PCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG-QCINTDGSFRCE 2197
C+L DVN+C G C +G C + ++C
Sbjct: 419 TCQL----------------------------DVNDCR---GQCQHGGTCKDLVNGYQCV 447
Query: 2198 CPMGYNLDYTGVRC-VDTDECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCE-DI 2254
CP G+ G C ++ DEC+ +PC G C ++ F C+C +GF GP+ CE D+
Sbjct: 448 CPRGFG----GRHCELERDECA-SSPCHSGGLCEDLADGFHCHCPQGFS-GPL--CEVDV 499
Query: 2255 NECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQK--------MCKDLDEC-------- 2298
+ C +P RC N G Y C CP + + C+ +D C
Sbjct: 500 DLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGM 559
Query: 2299 ----AEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDE-NECRTKPGICENG- 2352
A G+ C G G F CIC G G C + ++C +P C NG
Sbjct: 560 PGTAASGV--CGPHGRCVSQPGGNFSCICDSGFT----GTYCHENIDDCLGQP--CRNGG 611
Query: 2353 RCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCC 2412
C++ + ++RC C G++ E D C + C +LV C C
Sbjct: 612 TCIDEVDAFRCFCPSGWEG-----ELCDTNPNDCLPDP----CHSRGRCYDLVNDFYCAC 662
Query: 2413 DGG------RGWGHQCEL--CPLPGTAQ-----YKKICPHG-PGYTTDGRDIDECKVMPN 2458
D G QC+ C GT ++ CP G G T C +PN
Sbjct: 663 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC--LPN 720
Query: 2459 LCTNG-QCINTMGSFRCFCKVGYTTDISGTSCI-DLDECSQSPKPCNYICKNTEGSYQCS 2516
C NG C+ + SF C C+ G+ G +C + ++C+ P IC + ++C
Sbjct: 721 PCVNGGTCVGSGASFSCICRDGW----EGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 2517 CPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPG 2561
C G+ G C+ ++DECQ+ CV+ + G+ C CPPG
Sbjct: 777 CAPGFA----GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 818
Score = 164 bits (414), Expect = 2e-39
Identities = 191/741 (25%), Positives = 281/741 (37%), Gaps = 179/741 (24%)
Query: 1136 GSFECE------CFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGH 1189
G + C+ C +G+ M K C + C++ L GG V E C C G
Sbjct: 219 GHYTCDQYGNKACMDGW-----MGKECKEA-VCKQGCNLLHGGCTVPGE----CRCSYGW 268
Query: 1190 ELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNP---GYQATPDRQGCTDIDEC 1246
+ ++CV C +G CV +QC+C G D C C
Sbjct: 269 Q-GRFCDECVPYPGCV-------HGSCVE---PWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1247 MIMNGGCDTQCTNSE-GSYECSCSEGYALMPDGRSCADIDE-CENNPDICDGGQCTNIPG 1304
NGG C N+E Y C+C +GY+ GR+C + C +NP +GG C +P
Sbjct: 318 T--NGGT---CINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNP-CANGGSCHEVPS 367
Query: 1305 EYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMF-GECENTKGSFICHCQLGYSVKKGT 1362
+ C C G+ TC +D++EC SN C G C + F C C + G
Sbjct: 368 GFECHCPSGWSG----PTCALDIDEC--ASNPCAAGGTCVDQVDGFECICPEQW---VGA 418
Query: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSIN 1422
T DV++C C +C ++ ++C C G+ G + ++ DEC++ C
Sbjct: 419 TCQLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGFGGRHCE-LERDECASS--PCHSG 472
Query: 1423 AQCVNTPGSYRCACSEGFTGDGFTCS-DVDECAENINLCENG-QCLNVPGAYRCECEMGF 1480
C + + C C +GF+G C DVD C + C NG +C N+ G Y C C F
Sbjct: 473 GLCEDLADGFHCHCPQGFSGP--LCEVDVDLCEP--SPCRNGARCYNLEGDYYCACPDDF 528
Query: 1481 TPASDS--------RSCQDIDEC-----------SFQNIC-VFGTCNNLP-GMFHCICDD 1519
+ S +C+ ID C + +C G C + P G F CICD
Sbjct: 529 GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 588
Query: 1520 GYELDRTGGNC-TDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGN 1578
G+ TG C +ID+C G C++ + C CP ++ G C D +
Sbjct: 589 GF----TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE----GELC-DTNPND 639
Query: 1579 CYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEG 1638
C C S G+ + VN ++Y C G
Sbjct: 640 CL-----------------------PDPCHSRGRCY-------DLVN--DFYCACDDGWK 667
Query: 1639 FRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFA 1698
+ D C GG C ++ +F+C CP G+ T C
Sbjct: 668 GKTCHSREFQCDAYTCS------NGGTCYDSGDTFRCACPPGW--KGSTCAVAKNSSCLP 719
Query: 1699 HPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVT 1758
+P V G GTC + +++CIC + HN D C YNG C +
Sbjct: 720 NPCVNG-GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC---YNGGICVD------- 768
Query: 1759 KRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGI 1818
G W + CE P D + ++IDEC+ P
Sbjct: 769 ----------GVNWFR-CECAPGFAGPDCR------------------INIDECQSSP-- 797
Query: 1819 CANG-VCINQIGSFRCECPTG 1838
CA G C+++I +RC CP G
Sbjct: 798 CAYGATCVDEINGYRCSCPPG 818
Score = 132 bits (332), Expect = 5e-30
Identities = 100/313 (31%), Positives = 144/313 (46%), Gaps = 52/313 (16%)
Query: 2425 CPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDI 2484
C +PG + C +G GR DEC P C +G C+ ++C C+ T+
Sbjct: 256 CTVPGECR----CSYG----WQGRFCDECVPYPG-CVHGSCVEP---WQCNCE----TNW 299
Query: 2485 SGTSCI-DLDECSQSPKPCNY--ICKNTE-GSYQCSCPRGYVLQEDGKTCKDLDE-CQTK 2539
G C DL+ C S PC C N E Y+C+CP GY G+ C+ + C +
Sbjct: 300 GGLLCDKDLNYCG-SHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSN 354
Query: 2540 QHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCEC 2599
C GF C CP G++ T +D +EC S P C A G C + F C C
Sbjct: 355 PCANGGSCHEVPSGFECHCPSGWSGP-TCALDIDECASNP--CAAGGTCVDQVDGFECIC 411
Query: 2600 QRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGY-IQHYQWNQCVDE 2655
+ G C+ DV++C G +CQHG C++++ GY+C CP+G+ +H + ++
Sbjct: 412 PEQW----VGATCQLDVNDCRG--QCQHGGTCKDLVNGYQCVCPRGFGGRHCE----LER 461
Query: 2656 NECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACH-DVNECSSSKNPCNYG--CSN 2712
+EC++ C + + C CP GFS C DV+ C S PC G C N
Sbjct: 462 DECASSPCHSGGLCEDLADGFHCHCPQGFS----GPLCEVDVDLCEPS--PCRNGARCYN 515
Query: 2713 TEGGYLCGCPPGY 2725
EG Y C CP +
Sbjct: 516 LEGDYYCACPDDF 528
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 14/133 (10%)
Query: 90 GSRFHSYCCPGWK----TLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKS 145
G F C PGWK + + C+ C N C C G TC +
Sbjct: 693 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT 752
Query: 146 IQQCSVRCMNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC---IGPNR 195
+ C NGG C D C+C G+ G C + E + C G C I R
Sbjct: 753 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 812
Query: 196 CACVYGFTGPQCE 208
C+C G GP+C+
Sbjct: 813 CSCPPGRAGPRCQ 825
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 232 bits (592), Expect = 4e-60
Identities = 161/490 (32%), Positives = 238/490 (48%), Gaps = 65/490 (13%)
Query: 1834 ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVD 1892
+CP+GF+ + + C D DEC+ G N C + C N+ G+Y C C G ++ +G C D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAG-NPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 1893 RNECLEIPNVCSHGL-CVDLQGSYQCI--CHNGFKASQDQTMCMDVDEC-ERHPCGNGTC 1948
+EC + C G C + GSY+C+ C +GF+ + D C D++EC E PC + C
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRC 5206
Query: 1949 KNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCR-NGRCFNEIGSFKC--LCNEGY 2005
N +GS++C C PG++L C+D++EC VCR + C N G +KC LC G
Sbjct: 5207 FNAIGSFHCGCEPGYQL-KGRKCMDVNECRQ---NVCRPDQHCKNTRGGYKCIDLCPNGM 5262
Query: 2006 ELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCICPPGYEVK--SENCIDINECDE 2062
+G CID +EC C C+N GS+RC+CP GY + C+DINEC++
Sbjct: 5263 TKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 2063 DPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA-FNT 2121
P C C+NTPG F+C+CPPG L +G+ C + N+ S A F+
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLER---LPNYGTQYSSYNLARFSP 5377
Query: 2122 TKAKCCCSKMPGEGWGDPCELCPKDDEV------------AFQDLCPYGHGTVPSLHDTR 2169
+ + P + + L E + CP G + HDT
Sbjct: 5378 VRN----NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGS---EASHDTC 5430
Query: 2170 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN-PCG-NGT 2227
D++EC E+ C + +C NT GS++C CP GY L + G C D DEC N CG N
Sbjct: 5431 VDIDEC-ENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 2228 CTNVIGSFEC---NCNEGFEPGP-----MMNCEDIN-ECAQNPLLCAFRCMNTFGSYECT 2278
C N+ GS++C C ++ P + NC + ECA +P ++ + +
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLV--------S 5540
Query: 2279 CPIGYALRED 2288
P G A +D
Sbjct: 5541 LPFGIATNQD 5550
Score = 232 bits (591), Expect = 5e-60
Identities = 152/437 (34%), Positives = 206/437 (47%), Gaps = 68/437 (15%)
Query: 1156 CMDIDECER-NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG 1214
C D DEC NP +C N G++ C CP G ++ C DI+EC+L + C G
Sbjct: 5105 CADEDECAAGNPC---SHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAG 5161
Query: 1215 K-CVNMIGTYQC--SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEG 1271
+ C N IG+Y+C C G++ T D C DI+EC + C +C N+ GS+ C C G
Sbjct: 5162 QDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPG 5220
Query: 1272 YALMPDGRSCADIDECENNPDICDGGQ-CTNIPGEYRC--LCYDGFMASMDMKTCIDVNE 1328
Y L GR C D++EC N +C Q C N G Y+C LC +G M + TCID++E
Sbjct: 5221 YQLK--GRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNG-MTKAENGTCIDIDE 5275
Query: 1329 CDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNI 1387
C ++ C + + CENT+GS+ C C GY + C D++ECE C C N
Sbjct: 5276 CKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNT 5333
Query: 1388 PGSFKCSCREGW--IGNGIKCIDLDECSN-GTHQCSIN---------------------- 1422
PGSFKC C G +G+G C L+ N GT S N
Sbjct: 5334 PGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSH 5393
Query: 1423 ------------AQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPG 1470
T + R C EG TC D+DEC EN + C++ +C N G
Sbjct: 5394 LYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDEC-ENTDACQH-ECKNTFG 5451
Query: 1471 AYRCECEMGFTPASDSRSCQDIDECSFQNICVFGT--CNNLPGMFHCI---CDDGYELDR 1525
+Y+C C G+ + ++CQDIDEC QN+ C N+ G + CI C Y+ D
Sbjct: 5452 SYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDP 5511
Query: 1526 TGG----NCTDID-ECA 1537
G NC D ECA
Sbjct: 5512 VSGFCLKNCPPNDLECA 5528
Score = 231 bits (588), Expect = 1e-59
Identities = 154/457 (33%), Positives = 206/457 (45%), Gaps = 93/457 (20%)
Query: 2239 CNEGF---EPGPMMNCEDINECAQ-NPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKD 2294
C GF GP C D +ECA NP C+ C N G+Y C+CP G + D + C+D
Sbjct: 5092 CPSGFTLDSVGPF--CADEDECAAGNP--CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCI--CPPGMARRPDGEGCVDENECRTKPGICENG 2352
+DECA G H C + G C N IG++ C+ C G R DG C D NEC+ + C
Sbjct: 5148 IDECALGRHTCHA-GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQ- 5204
Query: 2353 RCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCC 2412
RC N IGS+ C C G+Q G +C+D E Q +C + + C
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLK--GRKCMDVN------ECRQNVC-----------RPDQHC 5245
Query: 2413 DGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR--DIDECKVMPNLCTNGQ-CINTM 2469
RG G++C +CP+G +G DIDECK + C Q C NT
Sbjct: 5246 KNTRG-GYKCI-----------DLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTR 5293
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKT 2529
GS+RC C GY + G C+D++EC Q PKPC + C NT GS++C CP G L DGK+
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 2530 CKDLDEC----------------------QTKQH---------------NCQFLCVNTLG 2552
C L+ Q +QH N + T
Sbjct: 5354 CAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRR 5413
Query: 2553 GFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC 2612
CP G H C+D +EC + + + C+NT GS+ C C G+ L G C
Sbjct: 5414 TIRKTCPEGSEASHDTCVDIDECENTDA---CQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Query: 2613 EDVDEC-DGNHRC--QHGCQNILGGYRC---GCPQGY 2643
+D+DEC + N C C N+ G Y+C CP Y
Sbjct: 5471 QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Score = 227 bits (578), Expect = 1e-58
Identities = 144/449 (32%), Positives = 202/449 (44%), Gaps = 64/449 (14%)
Query: 1177 TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPD 1236
++G CP G L C D +EC+ + N C + C N +GTY CSC G D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECA-AGNPCSHS-CHNAMGTYYCSCPKGLTIAAD 5141
Query: 1237 RQGCTDIDECMIMNGGCDT--QCTNSEGSYEC--SCSEGYALMPDGRSCADIDECENNPD 1292
+ C DIDEC + C C N+ GSY C C G+ DG SC DI+EC+ +
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201
Query: 1293 ICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFICH 1351
+C N G + C C G+ + + C+DVNEC N+C + C+NT+G + C
Sbjct: 5202 CHQ--RCFNAIGSFHCGCEPGYQ--LKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCI 5255
Query: 1352 CQLGYSVKKGTTG-CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGI--KCID 1408
+ K G C D+DEC+ G H C + C N GS++C C G+ G+ C+D
Sbjct: 5256 DLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Query: 1409 LDECSNGTHQCSINAQCVNTPGSYRCACSEG--FTGDGFTCSDVDECAE------NINLC 1460
++EC C+ QC NTPGS++C C G GDG +C+ ++ + NL
Sbjct: 5316 INECEQVPKPCA--HQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLA 5373
Query: 1461 ENGQCLN------------------------------VPGAYRCECEMGFTPASDSRSCQ 1490
N R C G + D+ C
Sbjct: 5374 RFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDT--CV 5431
Query: 1491 DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP-INC-VNGLCV 1548
DIDEC + C C N G + CIC GY+L G C DIDEC + ++C N +C
Sbjct: 5432 DIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 1549 NTPGRYEC---NCPPDFQLNPTGVGCVDN 1574
N G Y+C CPP++Q +P C+ N
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFCLKN 5519
Score = 223 bits (567), Expect = 3e-57
Identities = 153/472 (32%), Positives = 199/472 (42%), Gaps = 104/472 (22%)
Query: 2279 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2338
CP G+ L C D DECA G + C C N +GT+ C CP G+ DG C D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS---CHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 2339 ENECRTKPGICENGR-CVNIIGSYRC--ECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC 2395
+EC C G+ C N IGSYRC C GF+ +S G C D + C
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE-----------C 5196
Query: 2396 QMASSSR----NLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR--- 2448
Q +S N + C C+ PGY GR
Sbjct: 5197 QESSPCHQRCFNAIGSFHCGCE---------------------------PGYQLKGRKCM 5229
Query: 2449 DIDECKVMPNLCTNGQ-CINTMGSFRCF--CKVGYTTDISGTSCIDLDECSQSPKPCNY- 2504
D++EC+ N+C Q C NT G ++C C G T +GT CID+DEC C Y
Sbjct: 5230 DVNECR--QNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYN 5286
Query: 2505 -ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPG-- 2561
IC+NT GSY+C CPRGY Q G+ C D++EC+ C C NT G F C CPPG
Sbjct: 5287 QICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQH 5346
Query: 2562 --------------------FTQHHTACIDNNECGSQPS--------LCGAKGICQNTPG 2593
++ ++ A QP L + +N+
Sbjct: 5347 LLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRT 5406
Query: 2594 SFSCE-------CQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQH 2646
S S C G +A+ C D+DEC+ CQH C+N G Y+C CP GY
Sbjct: 5407 SLSRTRRTIRKTCPEGS--EASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLT 5464
Query: 2647 YQWNQCVDENECSNPNA-CG-SASCYNTLGSYKC---ACPSGFSFDQFSSAC 2693
+ C D +EC N CG + C+N GSY+C CP + D S C
Sbjct: 5465 HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 210 bits (534), Expect = 2e-53
Identities = 152/495 (30%), Positives = 218/495 (44%), Gaps = 94/495 (18%)
Query: 974 SKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAW 1033
SKG +CP G TLD G C D EDEC A
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCAD-----------EDEC-------------------AA 5113
Query: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK-CRNT 1092
G C Y CP+G A G +DI+EC C G+ C NT
Sbjct: 5114 GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTC------QDIDECALGRHTCHAGQDCDNT 5167
Query: 1093 IGSFKC--RCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGF 1150
IGS++C RC SGF + +C DI+EC+ S C C N GSF C C GY+
Sbjct: 5168 IGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-CHQR-CFNAIGSFHCGCEPGYQ--- 5222
Query: 1151 MMMKNCMDIDECERNPLLCRGGT-CVNTEGSFQCD--CPLGHELSPSREDCVDINECSLS 1207
+ + CMD++EC +N +CR C NT G ++C CP G + + C+DI+EC
Sbjct: 5223 LKGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDG 5279
Query: 1208 DNLCR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC 1266
+ CR N C N G+Y+C C GY++ + C DI+EC + C QC+N+ GS++C
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKC 5339
Query: 1267 SCSEGYALMPDGRSCADIDECENNPDICDG-------------------GQCTNIPGEY- 1306
C G L+ DG+SCA ++ N Q +++ Y
Sbjct: 5340 ICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYS 5399
Query: 1307 ----------------RCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFIC 1350
R C +G AS D TC+D++EC+ N++ C EC+NT GS+ C
Sbjct: 5400 EYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECE-NTDACQH-ECKNTFGSYQC 5455
Query: 1351 HCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKC---SCREGWIGNGIKCI 1407
C GY + C D+DEC +C + C N+ GS++C C + + +
Sbjct: 5456 ICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGF 5515
Query: 1408 DLDECSNGTHQCSIN 1422
L C +C+++
Sbjct: 5516 CLKNCPPNDLECALS 5530
Score = 207 bits (528), Expect = 9e-53
Identities = 152/484 (31%), Positives = 209/484 (43%), Gaps = 100/484 (20%)
Query: 1919 CHNGFKASQDQTMCMDVDECER-HPCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDE 1976
C +GF C D DEC +PC + +C N +G+Y C C G + + C DIDE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 1977 CSSFFGQVCRNGR-CFNEIGSFKCL--CNEGYELTPDGKNCIDTNECVALPGSCSPGTCQ 2033
C+ C G+ C N IGS++C+ C G+ T DG +C D NEC S C
Sbjct: 5151 CA-LGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE--SSPCHQRCF 5207
Query: 2034 NLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGS-CTNTPGGFQC--LCPPGFVLS 2090
N GSF C C PGY++K C+D+NEC + N+C C NT GG++C LCP G +
Sbjct: 5208 NAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 2091 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA--KCCCSK-MPGEGWGDPCELCPKDD 2147
+NG C D + T+ +C + T+ +C C + +G G PC
Sbjct: 5266 ENGT-CIDIDECKDGTH----QCRYNQICENTRGSYRCVCPRGYRSQGVGRPCM------ 5314
Query: 2148 EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYT 2207
D+NEC + P C++ QC NT GSF+C CP G +L
Sbjct: 5315 -----------------------DINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGD 5350
Query: 2208 GVRCVDTDEC------------SIGNPCGNG-------------------------TCTN 2230
G C + + +P N + +
Sbjct: 5351 GKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 2231 VIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQK 2290
+ C EG E C DI+EC +N C C NTFGSY+C CP GY L + K
Sbjct: 5411 TRRTIRKTCPEGSEASHD-TCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHNGK 5468
Query: 2291 MCKDLDECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMARRPDGEGCV-----DENEC 2342
C+D+DEC E C MC N+ G++ CI CPP R P C+ ++ EC
Sbjct: 5469 TCQDIDECLEQNVHC-GPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Query: 2343 RTKP 2346
P
Sbjct: 5528 ALSP 5531
Score = 205 bits (522), Expect = 5e-52
Identities = 146/472 (30%), Positives = 203/472 (43%), Gaps = 98/472 (20%)
Query: 2155 CPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
CP G T+ S+ D +EC CS+ C N G++ C CP G + G C D
Sbjct: 5092 CPSGF-TLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 2215 DECSIG-NPCGNGT-CTNVIGSFEC--NCNEGFE-PGPMMNCEDINECAQNPLLCAFRCM 2269
DEC++G + C G C N IGS+ C C GF ++C+DINEC Q C RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQRCF 5207
Query: 2270 NTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI--CPPGM 2327
N GS+ C C GY L+ + C D++EC + + + CKN G + CI CP GM
Sbjct: 5208 NAIGSFHCGCEPGYQLKG--RKCMDVNECRQNVCRPDQH---CKNTRGGYKCIDLCPNGM 5262
Query: 2328 ARRPDGEGCVDENECRTKPGICE-NGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 2386
+ +G C+D +EC+ C N C N GSYRC C G++S G C+D +
Sbjct: 5263 TKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINE--- 5318
Query: 2387 FAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTD 2446
C + HQC P +K ICP G D
Sbjct: 5319 ------------------------CEQVPKPCAHQCSNTP----GSFKCICPPGQHLLGD 5350
Query: 2447 GRDIDECKVMPNLCTNGQCIN--------------------------------------- 2467
G+ + +PN T N
Sbjct: 5351 GKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSR 5410
Query: 2468 TMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDG 2527
T + R C G ++ S +C+D+DEC ++ C + CKNT GSYQC CP GY L +G
Sbjct: 5411 TRRTIRKTCPEG--SEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHNG 5467
Query: 2528 KTCKDLDECQTKQHNC--QFLCVNTLGGFTC---KCPPGFTQHHTA--CIDN 2572
KTC+D+DEC + +C +C N G + C CPP + + + C+ N
Sbjct: 5468 KTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKN 5519
Score = 202 bits (513), Expect = 5e-51
Identities = 126/355 (35%), Positives = 170/355 (47%), Gaps = 34/355 (9%)
Query: 2476 CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDE 2535
C G+T D G C D DEC+ PC++ C N G+Y CSCP+G + DG+TC+D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 2536 CQTKQHNCQFL--CVNTLGGFTC--KCPPGF--TQHHTACIDNNECGSQPSLCGAKGICQ 2589
C +H C C NT+G + C +C GF T +C D NEC + S C + C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQR--CF 5207
Query: 2590 NTPGSFSCECQRGFSLDATGLNCEDVDECDGNH-RCQHGCQNILGGYRCG--CPQGYIQH 2646
N GSF C C+ G+ L G C DV+EC N R C+N GGY+C CP G +
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKA 5265
Query: 2647 YQWNQCVDENECSN-PNACG-SASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKN 2704
C+D +EC + + C + C NT GSY+C CP G+ C D+NEC
Sbjct: 5266 EN-GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 2705 PCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGM------GFNKGQYLSLDTEVDEENALS 2758
PC + CSNT G + C CPPG + +G G +G+ G Y +L N
Sbjct: 5325 PCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSY-NLARFSPVRNNYQ 5383
Query: 2759 PEACYECKINGYSKKD---------SRQKRSIHEPDPTAVEQISLESVDMDSPVN 2804
P+ Y + YS SR +R+I + P E VD+D N
Sbjct: 5384 PQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECEN 5438
Score = 200 bits (509), Expect = 1e-50
Identities = 147/493 (29%), Positives = 200/493 (40%), Gaps = 105/493 (21%)
Query: 2323 CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
CP G G C DE+EC C + C N +G+Y C C +G ++ G C D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 2383 QGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG 2442
+ + + C N + C G G+
Sbjct: 5150 E----CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRR---------------------- 5183
Query: 2443 YTTDG---RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP 2499
T+DG +DI+EC+ + + +C N +GSF C C+ GY + G C+D++EC Q+
Sbjct: 5184 -TSDGLSCQDINECQ--ESSPCHQRCFNAIGSFHCGCEPGY--QLKGRKCMDVNECRQNV 5238
Query: 2500 KPCNYICKNTEGSYQCS--CPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFT 2555
+ CKNT G Y+C CP G E+G TC D+DEC+ H C++ +C NT G +
Sbjct: 5239 CRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYR 5297
Query: 2556 CKCPPGFTQHHTA--CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE 2613
C CP G+ C+D NEC P C + C NTPGSF C C G L G +C
Sbjct: 5298 CVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCICPPGQHLLGDGKSCA 5355
Query: 2614 DVDECDGNHRCQHGCQNIL-------------------------GGYRCG---------- 2638
++ N+ Q+ N+ YR
Sbjct: 5356 GLERLP-NYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRT 5414
Query: 2639 ----CPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACH 2694
CP+G + CVD +EC N +AC C NT GSY+C CP G+ C
Sbjct: 5415 IRKTCPEG--SEASHDTCVDIDECENTDAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQ 5471
Query: 2695 DVNECSSSKNPC--NYGCSNTEGGYLC---GCPPGYYR-VGQGHCVSGMGFNKGQYLSLD 2748
D++EC C N C N G Y C CPP Y R G C+ N
Sbjct: 5472 DIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPN-------- 5523
Query: 2749 TEVDEENALSPEA 2761
D E ALSP A
Sbjct: 5524 ---DLECALSPYA 5533
Score = 199 bits (506), Expect = 3e-50
Identities = 145/442 (32%), Positives = 190/442 (42%), Gaps = 76/442 (17%)
Query: 1344 TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--IG 1401
+KG C G+++ C D DEC G N H SC N G++ CSC +G
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECAAG--NPCSH-SCHNAMGTYYCSCPKGLTIAA 5140
Query: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCA--CSEGF--TGDGFTCSDVDECAENI 1457
+G C D+DEC+ G H C C NT GSYRC C GF T DG +C D++EC E+
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES- 5199
Query: 1458 NLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC---------------- 1501
+ C +C N G++ C CE G+ R C D++EC QN+C
Sbjct: 5200 SPCHQ-RCFNAIGSFHCGCEPGY--QLKGRKCMDVNECR-QNVCRPDQHCKNTRGGYKCI 5255
Query: 1502 ----------VFGT-------------------CNNLPGMFHCICDDGYELDRTGGNCTD 1532
GT C N G + C+C GY G C D
Sbjct: 5256 DLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMD 5315
Query: 1533 IDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD----NRVGNCYLKFGPRG 1587
I+EC P C + C NTPG ++C CPP L G C G Y +
Sbjct: 5316 INECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLAR 5374
Query: 1588 DGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITII 1647
+ N + + S S + N + T T CP EG + T +
Sbjct: 5375 FSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT-CP--EGSEASHDTCV 5431
Query: 1648 LEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG- 1706
DIDEC+ CQ C NTFGS+QC CP GY L+ + + C+DIDEC CGP
Sbjct: 5432 --DIDECENTDA-CQ-HECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNR 5487
Query: 1707 TCYNTLGNYTCI---CPPEYMQ 1725
C+N G+Y CI CPP Y +
Sbjct: 5488 MCFNMRGSYQCIDTPCPPNYQR 5509
Score = 189 bits (479), Expect = 4e-47
Identities = 133/465 (28%), Positives = 206/465 (44%), Gaps = 97/465 (20%)
Query: 1633 CPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICED 1692
CP G F + + D DEC G +C N G++ C CP+G ++ D R C+D
Sbjct: 5092 CPSG--FTLDSVGPFCADEDECAA--GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 1693 IDECFAHPGVCGPGT-CYNTLGNYTCI--CPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
IDEC C G C NT+G+Y C+ C + + + G +C D+ + C
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE-----------C 5196
Query: 1750 ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
+ P + + C +N +++ CEP + + K +D+
Sbjct: 5197 QESSPCH---QRC---FNAIGSFHCGCEP-------------------GYQLKGRKCMDV 5231
Query: 1810 DECKEIPGICA-NGVCINQIGSFRCE--CPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD 1866
+EC++ +C + C N G ++C CP G + + C DIDEC +G + C+ N
Sbjct: 5232 NECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQI 5288
Query: 1867 CINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA 1925
C N+ GSYRC C G++ G C+D NEC ++P C+H C + GS++CIC G
Sbjct: 5289 CENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHL 5347
Query: 1926 SQDQTMCMDVDECERH-------------PCGNG-------------------------T 1947
D C ++ + P N +
Sbjct: 5348 LGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS 5407
Query: 1948 CKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYEL 2007
T + C G E +H+ C+DIDEC + C++ C N GS++C+C GY+L
Sbjct: 5408 LSRTRRTIRKTCPEGSEASHDT-CVDIDECEN--TDACQH-ECKNTFGSYQCICPPGYQL 5463
Query: 2008 TPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCI---CPPGYE 2048
T +GK C D +EC+ C P C N+ GS++CI CPP Y+
Sbjct: 5464 THNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQ 5508
Score = 187 bits (474), Expect = 2e-46
Identities = 149/475 (31%), Positives = 200/475 (42%), Gaps = 68/475 (14%)
Query: 1436 CSEGFTGD--GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDID 1493
C GFT D G C+D DECA N C + C N G Y C C G T A+D R+CQDID
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 1494 ECSF-QNICVFGT-CNNLPGMFHCI--CDDGYELDRTGGNCTDIDECADPINCVNGLCVN 1549
EC+ ++ C G C+N G + C+ C G+ G +C DI+EC + C + C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFN 5208
Query: 1550 TPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS 1609
G + C C P +QL G C+D V C R + C
Sbjct: 5209 AIGSFHCGCEPGYQLK--GRKCMD--VNEC-----------------------RQNVC-- 5239
Query: 1610 LGKAWGNPCETCPPVNST-EYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CI 1667
P + C + LCP G N I DIDEC++ C+ C
Sbjct: 5240 ------RPDQHCKNTRGGYKCIDLCPNGMTKAENGTCI---DIDECKDGTHQCRYNQICE 5290
Query: 1668 NTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVN 1727
NT GS++C CP+GY R C DI+EC P C C NT G++ CICPP +
Sbjct: 5291 NTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLG 5349
Query: 1728 GGHNCMDMRK----SFCYRSYN---GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCP 1780
G +C + + Y SYN + N R Y+ +
Sbjct: 5350 DGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRN----SR 5405
Query: 1781 TPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFS 1840
T + +TI P + H VDIDEC+ C N GS++C CP G+
Sbjct: 5406 TSLSRTRRTIRKTCPEGSEASH-DTCVDIDECENTD--ACQHECKNTFGSYQCICPPGYQ 5462
Query: 1841 YNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRC---ECAAGFKLSP-NGACV 1891
C+DIDEC + C N C N GSY+C C ++ P +G C+
Sbjct: 5463 LTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 177 bits (448), Expect = 2e-43
Identities = 126/418 (30%), Positives = 174/418 (41%), Gaps = 81/418 (19%)
Query: 520 ECNMGYKQDANGD-CIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDID 577
+C G+ D+ G C D DEC + NPC++ C N G+YYC C G + C DID
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 578 ECIQNGVLCKNGR-CVNTDGSFQCI--CNAGFELTTDGKNCVDHDECTTTNMCLNGMCIN 634
EC C G+ C NT GS++C+ C +GF T+DG +C D +EC ++ C + C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFN 5208
Query: 635 EDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCD--CPPGLAVGM 692
GSF C C+PG+ L GR C DV+EC+ + HC N+ G ++C CP G+
Sbjct: 5209 AIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAE 5266
Query: 693 DGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANP--DYGFGEPCQPCPAKNSA 750
+G C+D C G + + C C G G PC
Sbjct: 5267 NG-TCIDI---DECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCM-------- 5314
Query: 751 EFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCID 810
DINEC P CA+ C N GS++C C G G++C
Sbjct: 5315 -----------------DINECEQVPKPCAHQ-CSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Query: 811 IDEC-----------------------------LVNRLLCDNGLCRNTPGSYSCT----- 836
++ + L RN+ S S T
Sbjct: 5357 LERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIR 5416
Query: 837 --CPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICID 892
CP G +TC DI+ECE+ C+N GS+ C C PG +L+ G C D
Sbjct: 5417 KTCPEGS--EASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 174 bits (442), Expect = 9e-43
Identities = 137/473 (28%), Positives = 201/473 (42%), Gaps = 93/473 (19%)
Query: 923 TLGAAWGSPCERCELDTACPRGLARIK-GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCE 981
TLG + + + CP G G C D +EC G + C N+ G+++C
Sbjct: 5074 TLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAA--GNPCSHSCHNAMGTYYCS 5131
Query: 982 CPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECP 1041
CP+GLT+ GR C DI DEC G+ A G +C+
Sbjct: 5132 CPKGLTIAADGRTCQDI-----------DEC---ALGRHTCHA---------GQDCDNT- 5167
Query: 1042 KPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCN 1101
Y + G+GF D L+ +DINEC+ + +C N IGSF C C
Sbjct: 5168 ---IGSYRCVVRCGSGFRRTSDGLS----CQDINECQE--SSPCHQRCFNAIGSFHCGCE 5218
Query: 1102 SGFALDMEERNCTDIDECRISPDLCGSGI-CVNTPGSFECECFEGYESGFMMMKN--CMD 1158
G+ L + R C D++ECR ++C C NT G ++C + +G +N C+D
Sbjct: 5219 PGYQL--KGRKCMDVNECR--QNVCRPDQHCKNTRGGYKC--IDLCPNGMTKAENGTCID 5272
Query: 1159 IDECERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCV 1217
IDEC+ CR C NT GS++C CP G+ C+DINEC C + +C
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCS 5331
Query: 1218 NMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD----------------------- 1254
N G+++C C PG D + C ++ + N G
Sbjct: 5332 NTPGSFKCICPPGQHLLGDGKSCAGLER--LPNYGTQYSSYNLARFSPVRNNYQPQQHYR 5389
Query: 1255 ----------------TQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQ 1298
T + + + +C EG D +C DIDECEN D C +
Sbjct: 5390 QYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECENT-DACQH-E 5445
Query: 1299 CTNIPGEYRCLCYDGFMASMDMKTCIDVNEC-DLNSNICMFGECENTKGSFIC 1350
C N G Y+C+C G+ + + KTC D++EC + N + C N +GS+ C
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 169 bits (429), Expect = 3e-41
Identities = 147/491 (29%), Positives = 191/491 (38%), Gaps = 128/491 (26%)
Query: 2162 VPSLH--DTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
V +LH D N+ E+ G + D S +CP G+ LD G C D DEC+
Sbjct: 5056 VETLHASSVESDYNQIEETLGFKIHASISKGDRSN--QCPSGFTLDSVGPFCADEDECAA 5113
Query: 2220 GNPCGNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPLLC--AFRCMNTFGSYE 2276
GNPC + +C N +G++ C+C +G C+DI+ECA C C NT GSY
Sbjct: 5114 GNPCSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYR 5172
Query: 2277 CT--CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGE 2334
C C G+ D C+D++EC E C R C N IG+F C C PG + G
Sbjct: 5173 CVVRCGSGFRRTSDGLSCQDINECQES-SPCHQR---CFNAIGSFHCGCEPGYQLK--GR 5226
Query: 2335 GCVDENECR------------TKPG-----ICENGR------------------------ 2353
C+D NECR T+ G +C NG
Sbjct: 5227 KCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYN 5286
Query: 2354 --CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECC 2411
C N GSYRC C G++S G C+D E Q A N +C
Sbjct: 5287 QICENTRGSYRCVCPRGYRSQGVGRPCMD------INECEQVPKPCAHQCSNTPGSFKCI 5340
Query: 2412 CDGGR---GWGHQC---ELCPLPGT-----------------------AQY--------- 2433
C G+ G G C E P GT QY
Sbjct: 5341 CPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSE 5400
Query: 2434 ---------------KKICPHGPGYTTDG-RDIDECKVMPNLCTNGQCINTMGSFRCFCK 2477
+K CP G + D DIDEC+ + C + +C NT GS++C C
Sbjct: 5401 YRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NTDACQH-ECKNTFGSYQCICP 5458
Query: 2478 VGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC---SCPRGYVLQEDGKTCKD 2532
GY +G +C D+DEC + C N +C N GSYQC CP Y Q D +
Sbjct: 5459 PGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY--QRDPVSGFC 5516
Query: 2533 LDECQTKQHNC 2543
L C C
Sbjct: 5517 LKNCPPNDLEC 5527
Score = 164 bits (415), Expect = 1e-39
Identities = 151/521 (28%), Positives = 212/521 (40%), Gaps = 95/521 (18%)
Query: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCA 731
H S+G CP G + G C D + EC
Sbjct: 5080 HASISKGDRSNQCPSGFTLDSVGPFCAD-------------------------EDECAA- 5113
Query: 732 NPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDIC-ANGICENL 787
G PC ++ C G+ I DGR DI+ECAL C A C+N
Sbjct: 5114 ------GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNT 5167
Query: 788 RGSYRC--NCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 845
GSYRC C SG+ + G +C DI+EC + + C N GS+ C C PGY +
Sbjct: 5168 IGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC--HQRCFNAIGSFHCGCEPGY--QL 5223
Query: 846 ETETCEDINECESNPC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQD 904
+ C D+NEC N C + C+N G + C L G+ ++ GTC I
Sbjct: 5224 KGRKCMDVNECRQNVCRPDQHCKNTRGGYKC-----IDLCPNGMTKAEN--GTC---IDI 5273
Query: 905 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGV--TCEDVNECEVF 962
C+ + C T G+ RC CPRG R +GV C D+NECE
Sbjct: 5274 DECKDGTHQCRYNQICENTRGS------YRC----VCPRGY-RSQGVGRPCMDINECEQV 5322
Query: 963 PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI-RMEQCYLKWDEDEC--IHPVPGK 1019
P C + +C N+ GSF C CP G L G G+ C + R+ ++ PV
Sbjct: 5323 PKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNN 5381
Query: 1020 FRMDACCCAVGAAWGTECE-----ECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDI 1074
++ + + E + CP G+ ++ V DI
Sbjct: 5382 YQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCV--------DI 5433
Query: 1075 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG-SGICVN 1133
+EC+ C + +C+NT GS++C C G+ L + C DIDEC CG + +C N
Sbjct: 5434 DECEN-TDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFN 5491
Query: 1134 TPGSFEC---ECFEGYE----SGFMMMKNCMDID-ECERNP 1166
GS++C C Y+ SGF +KNC D EC +P
Sbjct: 5492 MRGSYQCIDTPCPPNYQRDPVSGF-CLKNCPPNDLECALSP 5531
Score = 145 bits (366), Expect = 6e-34
Identities = 113/380 (29%), Positives = 159/380 (41%), Gaps = 66/380 (17%)
Query: 509 RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT-NGDCVNTPGSYYC--KCHAGFQ 565
RC + S+ C C GY+ C+DV+EC N C + C NT G Y C C G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGR-KCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 566 RTPTKQACIDIDECIQNGVLCK-NGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTT 624
+ CIDIDEC C+ N C NT GS++C+C G+ G+ C+D +EC
Sbjct: 5264 KAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV 5322
Query: 625 NMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDC 684
C N GSFKCIC PG L +G+ C ++ G + + + R +
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNY 5382
Query: 685 PPGLAVGMDGRVCVDTHMR--STCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQ 742
P H R S Y + R +++++ +
Sbjct: 5383 QP------------QQHYRQYSHLYSSYSE---YRNSRTSLSRTRRTIR----------K 5417
Query: 743 PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPD 802
CP + A H C DI+EC + D C + C+N GSY+C C GY+
Sbjct: 5418 TCPEGSEAS-HDTCV----------DIDECE-NTDACQHE-CKNTFGSYQCICPPGYQLT 5464
Query: 803 ASGRNCIDIDECLVNRLLC-DNGLCRNTPGSYSC---TCPPGYVFRTETETCEDINECES 858
+G+ C DIDECL + C N +C N GSY C CPP Y +
Sbjct: 5465 HNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY---------------QR 5509
Query: 859 NPCVNGACRNNLGSFNCECS 878
+P V+G C N + EC+
Sbjct: 5510 DP-VSGFCLKNCPPNDLECA 5528
Score = 119 bits (297), Expect = 6e-26
Identities = 137/510 (26%), Positives = 193/510 (37%), Gaps = 88/510 (17%)
Query: 165 QCQKGY----IGTYC--------GQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYR 212
QC G+ +G +C G P C + C N +G C+C G T D R
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNA---MGTYYCSCPKGLT---IAADGR 5143
Query: 213 TGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTG 272
T Q ++ G+ T C TIG + C + C GF
Sbjct: 5144 T----CQDIDECALGRHTCHAGQD--CDNTIG---SYRCVV------RCGSGFRRTSDGL 5188
Query: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
+CQD++ECQ Q C N +GSF C C G++ +KC D++EC +C
Sbjct: 5189 SCQDINECQESSPCHQ--RCFNAIGSFHCGCEPGYQLKG--RKCMDVNECR--QNVCRPD 5242
Query: 333 E-CSNTVGSYFCV--CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCC 389
+ C NT G Y C+ CP G +T + CID C G R Q +C
Sbjct: 5243 QHCKNTRGGYKCIDLCPNG-MTKAENGTCID--IDECKDGTHQCRYNQICENTRGSYRCV 5299
Query: 390 CEPG-RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNG--FAPSG 446
C G R G+G R CMD +P + T G+ P G
Sbjct: 5300 CPRGYRSQGVG---------------RPCMDINECEQVPKPCAHQCSNTPGSFKCICPPG 5344
Query: 447 N---GNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHAN 503
G+G G +P G S + P + ++ +
Sbjct: 5345 QHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNS 5404
Query: 504 LCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAG 563
R T+ R C G + ++ C+D+DEC + +C NT GSY C C G
Sbjct: 5405 RTSLSRTRRTI---RKTCPEG-SEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPG 5460
Query: 564 FQRTPTKQACIDIDECIQNGVLC-KNGRCVNTDGSFQCI---CNAGFELTTDG----KNC 615
+Q T + C DIDEC++ V C N C N GS+QCI C ++ KNC
Sbjct: 5461 YQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNC 5520
Query: 616 VDHD-ECTTTNMCLN--------GMCINED 636
+D EC + L G+ N+D
Sbjct: 5521 PPNDLECALSPYALEYKLVSLPFGIATNQD 5550
Score = 116 bits (291), Expect = 3e-25
Identities = 57/142 (40%), Positives = 74/142 (52%), Gaps = 5/142 (3%)
Query: 2593 GSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQC 2652
G S +C GF+LD+ G C D DEC + C H C N +G Y C CP+G C
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 2653 VDENECS-NPNAC-GSASCYNTLGSYKCA--CPSGFSFDQFSSACHDVNECSSSKNPCNY 2708
D +EC+ + C C NT+GSY+C C SGF +C D+NEC S +PC+
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES-SPCHQ 5204
Query: 2709 GCSNTEGGYLCGCPPGYYRVGQ 2730
C N G + CGC PGY G+
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGR 5226
Score = 90.1 bits (222), Expect = 3e-17
Identities = 80/277 (28%), Positives = 105/277 (37%), Gaps = 61/277 (22%)
Query: 107 GNQCIVPICRNSCGDGFCSRPN---------MC-----------TCSSGQ-ISSTCGSKS 145
GN C C N+ G +CS P C TC +GQ +T GS
Sbjct: 5114 GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS-- 5170
Query: 146 IQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGP 205
+C VRC +G D CQ N CQ C RC G
Sbjct: 5171 -YRCVVRCGSGFRRTSDGLSCQD------------INECQESSPC--HQRCFNAIGSFHC 5215
Query: 206 QCERDYRTGPCFTQVNNQMCQ--GQLTGIVCTKTLCCATIGRAWGHPC-EMCPAQPQPCR 262
CE Y Q+ + C + VC C G+ C ++CP
Sbjct: 5216 GCEPGY-------QLKGRKCMDVNECRQNVCRPDQHCKNT--RGGYKCIDLCP------- 5259
Query: 263 RGFIPNIRTGACQDVDECQAIPGICQGGN-CINTVGSFECRCPAGHKQSETTQKCEDIDE 321
+ G C D+DEC+ C+ C NT GS+ C CP G++ + C DI+E
Sbjct: 5260 -NGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINE 5318
Query: 322 CSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
C +P C +CSNT GS+ C+CP G DG C
Sbjct: 5319 CEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSC 5354
Score = 77.0 bits (188), Expect = 2e-13
Identities = 87/316 (27%), Positives = 118/316 (37%), Gaps = 65/316 (20%)
Query: 108 NQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQ 167
NQC +S G FC+ + C + S + CS C G T A D CQ
Sbjct: 5090 NQCPSGFTLDSVGP-FCADEDECAAGNPCSHSCHNAMGTYYCS--CPKGLTIAADGRTCQ 5146
Query: 168 KGYIGTYCGQPVCENGCQNGGRCIGPNRCA--CVYGFT----GPQCE---RDYRTGPCFT 218
G+ C G Q+ IG RC C GF G C+ + PC
Sbjct: 5147 D-IDECALGRHTCHAG-QDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-- 5202
Query: 219 QVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVD 278
+Q C + C C G+ ++ C DV+
Sbjct: 5203 ---HQRCFNAIGSFHCG-------------------------CEPGY--QLKGRKCMDVN 5232
Query: 279 ECQAIPGICQGG-NCINTVGSFEC--RCPAGHKQSETTQKCEDIDECSIIPGICETGE-C 334
EC+ +C+ +C NT G ++C CP G ++E C DIDEC C + C
Sbjct: 5233 ECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQIC 5289
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGR 394
NT GSY CVCPRGY + G C+D C V CA + +C C PG+
Sbjct: 5290 ENTRGSYRCVCPRGYRSQGVGRPCMD--INECEQ--VPKPCAHQCSNTPGSFKCICPPGQ 5345
Query: 395 --------CWGIGTIP 402
C G+ +P
Sbjct: 5346 HLLGDGKSCAGLERLP 5361
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 231 bits (589), Expect = 8e-60
Identities = 132/372 (35%), Positives = 192/372 (51%), Gaps = 38/372 (10%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCD----C 1185
C +T C CF GY+ +C D++EC CR G +C+NT GSF+C C
Sbjct: 190 CRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMIGTYQC----SCNPGYQATPDRQG- 1239
G+EL+ C DI+EC + C + C N +G+++C C G+ D G
Sbjct: 249 GTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALGN 305
Query: 1240 CTDIDECMIMNGGCDT--QCTNSEGSYEC-----SCSEGYALMPDGRSCADIDECENNPD 1292
C DI+EC+ ++ C C N+EGSY C +C GY L +G C D+DEC +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 1293 ICDGG-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICH 1351
C G +C N PG +RC C G+ + C+DVNEC +CENT GS++C
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW---IGNGIKCID 1408
C +G+ + C D++EC + C N+ GS++C CR G+ +G+ C D
Sbjct: 426 CSVGFRLSVDGRSCEDINECS----SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 1409 LDECS--NGTHQCSINAQCVNTPGSYRCAC-SEGF--TGDGFTCSDVDECAENINLCE-N 1462
+DEC+ G H CS +C+N PGS++C+C S G+ +G C D+DEC I+ C N
Sbjct: 482 IDECALPTGGHICSY--RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1463 GQCLNVPGAYRC 1474
C N+ G +RC
Sbjct: 540 ETCFNIQGGFRC 551
Score = 221 bits (562), Expect = 1e-56
Identities = 143/424 (33%), Positives = 193/424 (45%), Gaps = 68/424 (16%)
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEP-GPMMNCEDINECAQNPLLCAF--RCMNT 2271
D C G PC C + C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2272 FGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----C 2323
GS+ C +C GY L ED CKD+DEC G+H+C +C+N +G+F C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLP-DFICQNTLGSFRCRPKLQC 294
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGR-CVNIIGSYRCE-----CNEGFQSSSSGTE 2377
G + G C+D NEC + C G C+N GSY C+ C G+ + GT
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2378 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2437
C+D + +E C G GH+C PG+ + C
Sbjct: 354 CVDVDE--------------------CAPPAEPC-----GKGHRC--VNSPGSFR----C 382
Query: 2438 PHGPGYTTDGR-----DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL 2492
GY DG D++EC+ P +C NT+GS+ C C VG+ + G SC D+
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2493 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE-DGKTCKDLDEC--QTKQHNCQFLCVN 2549
+ECS S PC+ C N GSYQC C RGY L + DG TC+D+DEC T H C + C+N
Sbjct: 443 NECSSS--PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 2550 TLGGFTCKCPPG---FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC---ECQRGF 2603
G F C CP + C D +EC + C C N G F C EC +
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 2604 SLDA 2607
A
Sbjct: 561 RRSA 564
Score = 213 bits (541), Expect = 3e-54
Identities = 139/393 (35%), Positives = 185/393 (47%), Gaps = 57/393 (14%)
Query: 2363 CECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQC 2422
C C G+Q S G C D + + + C++ S N V C D G G++
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHS----CRLGESCINTVGSFRCQRDSSCGTGYEL 254
Query: 2423 ELCPLPGTAQYKKICPHGPGYTTDG--RDIDECKV-MPNLCTNGQCINTMGSFRCF---- 2475
T D +DIDEC+ + N + C NT+GSFRC
Sbjct: 255 ---------------------TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 2476 CKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC-----SCPRGYVLQEDGK 2528
CK G+ D G +CID++EC PC + C NTEGSY C +C RGY L E+G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 2529 TCKDLDECQTKQHNCQ--FLCVNTLGGFTCKCPPG--FTQHHTACIDNNECGSQPS-LCG 2583
C D+DEC C CVN+ G F C+C G F C+D NEC P LCG
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 2584 AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGY 2643
K C+NT GS+ C C GF L G +CED++EC + C C N+ G Y+C C +GY
Sbjct: 413 HK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECANVYGSYQCYCRRGY 469
Query: 2644 -IQHYQWNQCVDENECSNPNACGSAS--CYNTLGSYKCACPS-GFSFDQFSSACHDVNEC 2699
+ C D +EC+ P S C N GS++C+CPS G+ C D++EC
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2700 SSSKNPC--NYGCSNTEGGYLC---GCPPGYYR 2727
+ + C N C N +GG+ C CP Y R
Sbjct: 530 VTGIHNCSINETCFNIQGGFRCLAFECPENYRR 562
Score = 211 bits (536), Expect = 1e-53
Identities = 145/414 (35%), Positives = 202/414 (48%), Gaps = 62/414 (14%)
Query: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGR-CFNEIGSFKC 1999
PC C++T C C+ G++L + C D++EC + CR G C N +GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITG-SHSCRLGESCINTVGSFRC 242
Query: 2000 L----CNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCI----CPPGY-EV 2049
C GYELT D +C D +EC + +C P CQN GSFRC C G+ +
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 2050 KSENCIDINECDEDPNICLFG-SCTNTPGGFQCL-----CPPGFVLSDNGRRCFDTRQSF 2103
NCIDINEC C G +C NT G + C C G+ L++ G RC D +
Sbjct: 302 ALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE-- 359
Query: 2104 CFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
C+ P A+ C G G C P +F+ C G+
Sbjct: 360 ---------CAPP-------AEPC-------GKGHRCVNSPG----SFRCECKTGY-YFD 391
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
+ DVNEC PG +C NT GS+ C C +G+ L G C D +ECS +PC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPC 450
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGPM--MNCEDINECA--QNPLLCAFRCMNTFGSYECTC 2279
C NV GS++C C G++ + + CEDI+ECA +C++RC+N GS++C+C
Sbjct: 451 SQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSC 509
Query: 2280 P-IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMAR 2329
P GY L + + C+D+DEC G+H+C S C N+ G F C+ CP R
Sbjct: 510 PSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (528), Expect = 9e-53
Identities = 177/614 (28%), Positives = 242/614 (39%), Gaps = 122/614 (19%)
Query: 1166 PLLCRGGTC-----VNTEGSFQCDCPLGHELSPSREDC-----VDINECSLSDNLCRNGK 1215
PLL GG V+ + + C GH ++ ++DC + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG-GCDTQCTNSEGSYECSCSEGYAL 1274
C + + C+ DR C +G + T + C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDR--------CATPHGDNASLEATFVKRCCHC-CLLGRAA 119
Query: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD---------GFMASMDMKTCID 1325
G+SC + G QC + +R C G + D ++
Sbjct: 120 QAQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVE 168
Query: 1326 VNECD--LNSNICMFG-----ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
+ D LN C G +C +T +C C +GY + C DV+EC G+H+C
Sbjct: 169 EEQEDPYLNDR-CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1379 DMHASCLNIPGSFKC----SCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ SC+N GSF+C SC G+ + C D+DEC +G H C + C NT GS+R
Sbjct: 228 RLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 1434 C----ACSEGFTGDGF-TCSDVDECAENINLCENGQ-CLNVPGAYRCE-----CEMGFTP 1482
C C GF D C D++EC C G C+N G+Y C+ C G+
Sbjct: 288 CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 1483 ASDSRSCQDIDECS-FQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-P 1539
+ C D+DEC+ C G C N PG F C C GY D C D++EC P
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP 407
Query: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
C NT G Y C+C F+L+ G C D + C S C+ E
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INEC---------SSSPCSQECAN 456
Query: 1600 GVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
C C G Y L + + EDIDEC
Sbjct: 457 VYGSYQCYCRRG------------------YQL--------SDVDGVTCEDIDEC----A 486
Query: 1660 LCQGGN-----CINTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTL 1712
L GG+ CIN GSFQC CP GY L+ + R C+DIDEC C TC+N
Sbjct: 487 LPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQ 546
Query: 1713 GNYTCI---CPPEY 1723
G + C+ CP Y
Sbjct: 547 GGFRCLAFECPENY 560
Score = 204 bits (518), Expect = 1e-51
Identities = 136/408 (33%), Positives = 186/408 (45%), Gaps = 61/408 (14%)
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC-- 2321
C +C +T C+C +GY L D C+D++EC G H C G C N +G+F C
Sbjct: 186 CKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL-GESCINTVGSFRCQR 244
Query: 2322 --ICPPGMARRPDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRC----ECNEGFQSSSS 2374
C G D C D +EC + C + C N +GS+RC +C GF +
Sbjct: 245 DSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 2375 GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYK 2434
G C+D + L + C + GH C T Q K
Sbjct: 304 GN-CIDINECLS----ISAPCPI---------------------GHTCINTEGSYTCQ-K 336
Query: 2435 KICPHGPGYTTDGR-----DIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTS 2488
+ G GY + D+DEC C G +C+N+ GSFRC CK GY D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2489 CIDLDECSQSP-KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLC 2547
C+D++EC + P + C + C+NT GSY CSC G+ L DG++C+D++EC + C C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQEC 454
Query: 2548 VNTLGGFTCKCPPGFTQHHT---ACIDNNECGSQPS--LCGAKGICQNTPGSFSCEC-QR 2601
N G + C C G+ C D +EC +C + C N PGSF C C
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR--CINIPGSFQCSCPSS 512
Query: 2602 GFSLDATGLNCEDVDEC-DGNHRCQ--HGCQNILGGYRC---GCPQGY 2643
G+ L G NC+D+DEC G H C C NI GG+RC CP+ Y
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 196 bits (497), Expect = 4e-49
Identities = 124/364 (34%), Positives = 170/364 (46%), Gaps = 48/364 (13%)
Query: 2412 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT--TDG---RDIDECKVMPNLCTNGQ-C 2465
C GG QC + +C GY +DG D++EC + C G+ C
Sbjct: 180 CRGGGPCKQQCR------DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESC 233
Query: 2466 INTMGSFRC----FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC---- 2515
INT+GSFRC C GY SC D+DEC C ++IC+NT GS++C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCK-----CPPGF--TQHH 2566
C G++ G C D++EC + C C+NT G +TC+ C G+ +
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 2567 TACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD--GNHRC 2624
T C+D +EC CG C N+PGSF CEC+ G+ D C DV+EC C
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 2625 QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 2684
H C+N LG Y C C G+ C D NECS+ + C S C N GSY+C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-SPC-SQECANVYGSYQCYCRRGY 469
Query: 2685 SF-DQFSSACHDVNECS--SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG--------HC 2733
D C D++EC+ + + C+Y C N G + C CP YR+ C
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2734 VSGM 2737
V+G+
Sbjct: 530 VTGI 533
Score = 194 bits (493), Expect = 1e-48
Identities = 135/401 (33%), Positives = 185/401 (46%), Gaps = 58/401 (14%)
Query: 970 RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAV 1029
+C ++ C C G L G C D+ +ECI ++C V
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDV-----------NECITGSHSCRLGESCINTV 237
Query: 1030 GAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK- 1088
G+ C+ GT G LT KDI+EC++ C
Sbjct: 238 GSF---RCQRDSSCGT----------------GYELTEDNSCKDIDECESGIHNCLPDFI 278
Query: 1089 CRNTIGSFKCR----CNSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFECE-- 1141
C+NT+GSF+CR C SGF D NC DI+EC C G C+NT GS+ C+
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 1142 ---CFEGY---ESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPS 1194
C GY E G C+D+DEC C +G CVN+ GSF+C+C G+
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD 1254
CVD+NEC KC N +G+Y CSC+ G++ + D + C DI+EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCS 451
Query: 1255 TQCTNSEGSYECSCSEGYALMP-DGRSCADIDEC--ENNPDICDGGQCTNIPGEYRCLC- 1310
+C N GSY+C C GY L DG +C DIDEC IC +C NIPG ++C C
Sbjct: 452 QECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCP 510
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFIC 1350
G+ + + + C D++EC + C E C N +G F C
Sbjct: 511 SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 194 bits (492), Expect = 1e-48
Identities = 138/435 (31%), Positives = 197/435 (45%), Gaps = 70/435 (16%)
Query: 1803 TGKAVDIDECKEIPGI---CANG-----VCINQIGSFRCECPTGFSYNDLLLVCEDIDEC 1854
T K ++++E +E P + C G C + C C G+ + CED++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 1855 SNGDNLCQRNADCINSPGSYRCE----CAAGFKLSPNGACVDRNECLE-IPNVCSHGLCV 1909
G + C+ CIN+ GS+RC+ C G++L+ + +C D +EC I N +C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 1910 DLQGSYQCI----CHNGFKASQDQT-MCMDVDECER--HPCGNG-TCKNTVGSYNCL--- 1958
+ GS++C C +GF QD C+D++EC PC G TC NT GSY C
Sbjct: 281 NTLGSFRCRPKLQCKSGF--IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 1959 --CYPGFELTHNND-CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 2015
C G+ L C+D+DEC+ + RC N GSF+C C GY + C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCT 2073
D NEC PG C+N GS+ C C G+ V +C DINEC P C
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP---CSQECA 455
Query: 2074 NTPGGFQCLCPPGFVLSD-NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMP 2132
N G +QC C G+ LSD +G C D +C++P + +C +P
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDI-----------DECALPTGGHICSYRCI--NIP 502
Query: 2133 GEGWGDPCELCPKDDEVAFQDLCP-YGHGTVPSLHDTREDVNECLESPGICS-NGQCINT 2190
G +FQ CP G+ P+ + +D++EC+ CS N C N
Sbjct: 503 G----------------SFQCSCPSSGYRLAPNGRNC-QDIDECVTGIHNCSINETCFNI 545
Query: 2191 DGSFRC---ECPMGY 2202
G FRC ECP Y
Sbjct: 546 QGGFRCLAFECPENY 560
Score = 193 bits (490), Expect = 2e-48
Identities = 137/454 (30%), Positives = 196/454 (43%), Gaps = 70/454 (15%)
Query: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKP 2346
E+++ L++ G C+ + C++ +C C G DG C D NEC T
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQ---CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS 224
Query: 2347 GICENGR-CVNIIGSYRCE----CNEGFQ-SSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
C G C+N +GS+RC+ C G++ + + + +D + + ICQ
Sbjct: 225 HSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLG 284
Query: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR----DIDECKVM 2456
S K +C G+ D DI+EC +
Sbjct: 285 SFRCRPKLQC-----------------------------KSGFIQDALGNCIDINECLSI 315
Query: 2457 PNLCTNGQ-CINTMGSFRCF-----CKVGYTTDISGTSCIDLDECSQSPKPCN--YICKN 2508
C G CINT GS+ C C GY + GT C+D+DEC+ +PC + C N
Sbjct: 316 SAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 2509 TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN-CQFLCVNTLGGFTCKCPPGF--TQH 2565
+ GS++C C GY + C D++ECQ C C NTLG + C C GF +
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVD 435
Query: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL-DATGLNCEDVDEC---DGN 2621
+C D NEC S P C + C N GS+ C C+RG+ L D G+ CED+DEC G
Sbjct: 436 GRSCEDINECSSSP--CSQE--CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGG 491
Query: 2622 HRCQHGCQNILGGYRCGCPQ-GYIQHYQWNQCVDENECSNP--NACGSASCYNTLGSYKC 2678
H C + C NI G ++C CP GY C D +EC N + +C+N G ++C
Sbjct: 492 HICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Query: 2679 ---ACPSGF---SFDQFSSACHDVNECSSSKNPC 2706
CP + + Q S SSK C
Sbjct: 552 LAFECPENYRRSAATQKSKKGRQNTPAGSSKEDC 585
Score = 184 bits (467), Expect = 1e-45
Identities = 130/381 (34%), Positives = 174/381 (45%), Gaps = 67/381 (17%)
Query: 493 QTIDICKHHANLCLNGR-CIPTVSSYRCE----CNMGYKQDANGDCIDVDECTS---NPC 544
+ ++ C ++ C G CI TV S+RC+ C GY+ + C D+DEC S N
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 545 TNGDCVNTPGSYYCK----CHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTDGSFQ 599
+ C NT GS+ C+ C +GF + CIDI+EC+ C G C+NT+GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 600 C-----ICNAGFELTTDGKNCVDHDECT-TTNMCLNG-MCINEDGSFKCICKPGFVLAPN 652
C C G+ L +G CVD DEC C G C+N GSF+C CK G+
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 653 GRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
R C DV+ECQ PG C N+ GS+ C C G + +DGR C D
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI----------- 442
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT-VDG---R 767
+EC PC A + C G ++ VDG
Sbjct: 443 --------------NECS--------SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 768 DINECALDP--DICANGICENLRGSYRCNC-NSGYEPDASGRNCIDIDECLVNRLLCD-N 823
DI+ECAL IC+ C N+ GS++C+C +SGY +GRNC DIDEC+ C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 824 GLCRNTPGSYSC---TCPPGY 841
C N G + C CP Y
Sbjct: 540 ETCFNIQGGFRCLAFECPENY 560
Score = 170 bits (430), Expect = 2e-41
Identities = 135/409 (33%), Positives = 177/409 (43%), Gaps = 73/409 (17%)
Query: 537 DECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTD 595
D C C +T C C G+Q +C D++ECI C+ G C+NT
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 596 GSFQC----ICNAGFELTTDGKNCVDHDECTT-TNMCL-NGMCINEDGSFKCI----CKP 645
GSF+C C G+ELT D +C D DEC + + CL + +C N GSF+C CK
Sbjct: 238 GSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 646 GFVLAPNGRYCTDVDECQTPGI-CMNGH-CINSEGSFRC-----DCPPGLAVGMDGRVCV 698
GF+ G C D++EC + C GH CIN+EGS+ C +C G + +G CV
Sbjct: 297 GFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 699 DTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSS 758
D EC G G C P E C +
Sbjct: 356 DV-------------------------DECAPPAEPCGKGHRCVNSPGSFRCE----CKT 386
Query: 759 GV---GITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL 815
G GI+ D+NEC P CEN GSY C+C+ G+ GR+C DI+EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 816 VNRLLCDNGLCRNTPGSYSCTCPPGY-VFRTETETCEDINEC---ESNPCVNGACRNNLG 871
+ + C N GSY C C GY + + TCEDI+EC + C N G
Sbjct: 447 SSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 872 SFNCEC-SPGSKLSSTGLICID-----------SLKGTCWLNIQDS-RC 907
SF C C S G +L+ G C D S+ TC+ NIQ RC
Sbjct: 504 SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRC 551
Score = 164 bits (416), Expect = 9e-40
Identities = 135/444 (30%), Positives = 187/444 (42%), Gaps = 91/444 (20%)
Query: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHC----IC 1517
QC + C C +G+ SD SC+D++EC + + C G +C N G F C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1518 DDGYELDRTGGNCTDIDECADPI-NCV-NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
GYEL +C DIDEC I NC+ + +C NT G + C P Q G + +
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQCKS---GFIQDA 302
Query: 1576 VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
+GNC + N + + S C +G TC +N+ YT
Sbjct: 303 LGNC-----------IDINECLSI-----SAPCPIG-------HTC--INTEGSYTCQKN 337
Query: 1636 ----GEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
G G+ N D+DEC C +G C+N+ GSF+CEC GYY +R+C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 1691 EDIDECFAHPG-VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
D++EC +PG +CG C NTLG+Y C C + G +C D+ + + + C
Sbjct: 398 VDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC------SSSPC 450
Query: 1750 ENELPFNVTKRMCCCT--YNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 1807
E C C Y + CE
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCE------------------------------ 480
Query: 1808 DIDECKEIPG--ICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
DIDEC G IC+ CIN GSF+C CP +G+ C+DIDEC G + C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1865 ADCINSPGSYRC---ECAAGFKLS 1885
C N G +RC EC ++ S
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRS 563
Score = 157 bits (398), Expect = 1e-37
Identities = 177/619 (28%), Positives = 238/619 (38%), Gaps = 131/619 (21%)
Query: 592 VNTDGSFQCICNAGFELTTDGKNC-----VDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
V+ D + C G + T K+C + EC M C ++ C G
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKEC---RMVQEQCCHSQLEELHCAT--G 81
Query: 647 FVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF--RCD--CPPGLAVGMDGRVCVDTHM 702
LA + D C TP +G + E +F RC C G A G+ C + M
Sbjct: 82 ISLA------NEQDRCATP----HGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLM 131
Query: 703 RSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGI 762
G + + CV+ S E L G+
Sbjct: 132 VGYQCGQVFRACCVK-------------------------------SQETGDLDVGGLQE 160
Query: 763 TVDGRDINECALDP---DICANG-----ICENLRGSYRCNCNSGYEPDASGRNCIDIDEC 814
T ++ E DP D C G C + C+C GY+ + G +C D++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 815 LVNRLLCDNG-LCRNTPGSYSC----TCPPGYVFRTETETCEDINECES---NPCVNGAC 866
+ C G C NT GS+ C +C GY TE +C+DI+ECES N + C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFIC 279
Query: 867 RNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGA 926
+N LGSF C KL D+L G C ++IN S C
Sbjct: 280 QNTLGSFRCR----PKLQCKSGFIQDAL-GNC----------IDINECLSISAPCPI--- 321
Query: 927 AWGSPCERCELDTACPRGLARI--------KGVTCEDVNECEVFPGVCPNG-RCVNSKGS 977
G C E C + + +G C DV+EC C G RCVNS GS
Sbjct: 322 --GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Query: 978 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG---AAWG 1034
F CEC G DG R+C+D+ Q Y C H C C+VG + G
Sbjct: 380 FRCECKTGYYFDGISRMCVDVNECQRY---PGRLCGHKCENTLGSYLCSCSVGFRLSVDG 436
Query: 1035 TECE---ECPK-PGTKE-------YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG- 1082
CE EC P ++E Y+ C RG ++ V +DI+EC G
Sbjct: 437 RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC-----EDIDECALPTGG 491
Query: 1083 -MCTYGKCRNTIGSFKCRC-NSGFALDMEERNCTDIDECRISPDLCG-SGICVNTPGSFE 1139
+C+Y +C N GSF+C C +SG+ L RNC DIDEC C + C N G F
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFR 550
Query: 1140 C---ECFEGYESGFMMMKN 1155
C EC E Y K+
Sbjct: 551 CLAFECPENYRRSAATQKS 569
Score = 144 bits (363), Expect = 1e-33
Identities = 118/398 (29%), Positives = 172/398 (43%), Gaps = 86/398 (21%)
Query: 273 ACQDVDECQAIPGICQ-GGNCINTVGSFECR----CPAGHKQSETTQKCEDIDEC-SIIP 326
+C+DV+EC C+ G +CINTVGSF C+ C G++ +E C+DIDEC S I
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIH 271
Query: 327 GICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM 386
C NT+GS+ RC + C SG + Q+ G
Sbjct: 272 NCLPDFICQNTLGSF---------------RCRPKL--QCKSGFI-----QDALGN---- 305
Query: 387 QCCCEPGRCWGIGTIPEACPVRGS---EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFA 443
C + C I CP+ + E C +P
Sbjct: 306 --CIDINECLSISA---PCPIGHTCINTEGSYTCQKNVPN-------------------- 340
Query: 444 PSGNGNGYGPGGTGFIPI--------PGGNGF----SPGVGGAGVGAGGQGPIITGLTIL 491
G G GT + + P G G SPG G G++ +
Sbjct: 341 -CGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYY---FDGISRM 396
Query: 492 NQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCV 550
++ C+ + +C T+ SY C C++G++ +G C D++EC+S+PC+ +C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ-ECA 455
Query: 551 NTPGSYYCKCHAGFQRTPTK-QACIDIDECI--QNGVLCKNGRCVNTDGSFQCIC-NAGF 606
N GSY C C G+Q + C DIDEC G +C + RC+N GSFQC C ++G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGY 514
Query: 607 ELTTDGKNCVDHDECTT--TNMCLNGMCINEDGSFKCI 642
L +G+NC D DEC T N +N C N G F+C+
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 99.0 bits (245), Expect = 6e-20
Identities = 99/327 (30%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 97 CCPGWKTLPGG------NQCIV--------PICRNSCGDGFCSRPNMCTCSSGQISSTCG 142
C G++ L G N+CI C N+ G C R + C + +++
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG-TGYELTEDNS 259
Query: 143 SKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNG------GRCIGPNRC 196
K I +C N C D CQ +G++ +P + C++G G CI N C
Sbjct: 260 CKDIDECESGIHN---CLPDFI-CQNT-LGSFRCRPKLQ--CKSGFIQDALGNCIDINEC 312
Query: 197 A-----CVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLT--GIVCTKTLCCATIGRAWG- 248
C G T E Y C V N L G C CA G
Sbjct: 313 LSISAPCPIGHTCINTEGSYT---CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK 369
Query: 249 -HPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H C P + C+ G+ + + C DV+ECQ PG G C NT+GS+ C C G
Sbjct: 370 GHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVG 429
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY-VTSTDGSRC--IDQRT 363
+ S + CEDI+ECS P C EC+N GSY C C RGY ++ DG C ID+
Sbjct: 430 FRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 364 GMCFSGLVNGRCAQELPGRMTKMQCCC 390
+ + RC +PG QC C
Sbjct: 487 LPTGGHICSYRCI-NIPG---SFQCSC 509
Score = 94.4 bits (233), Expect = 2e-18
Identities = 81/299 (27%), Positives = 113/299 (37%), Gaps = 66/299 (22%)
Query: 152 RCMNGGTCADDHCQCQKGYIGTYC----GQPVCENG--CQNGGRCI-GPNRC----ACVY 200
RC GG C QC+ C G + +G C++ CI G + C +C+
Sbjct: 179 RCRGGGPCKQ---QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 201 GFTGPQCERDYRTGP---------------CFTQVNNQM----CQGQLTGIVCTKTLCCA 241
+C+RD G C + ++N + CQ L C L C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 242 T--IGRAWGH------------PCEM------------CPAQPQPCRRGFIPNIRTGACQ 275
+ I A G+ PC + C C RG+ N C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 276 DVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
DVDEC C +G C+N+ GSF C C G+ ++ C D++EC PG +C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
NT+GSY C C G+ S DG C D + + C+QE QC C G
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQECANVYGSYQCYCRRG 468
Score = 87.8 bits (216), Expect = 1e-16
Identities = 95/297 (31%), Positives = 125/297 (42%), Gaps = 75/297 (25%)
Query: 114 ICRNSCGDGFCSRPNMCTCSSGQISSTCGSK-SIQQC---SVRCMNGGTCADDH----CQ 165
IC+N+ G C RP + C SG I G+ I +C S C G TC + CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 166 -----CQKGYI----GTYCGQ-----PVCENGCQNGGRCI---GPNRCACVYGFTGPQCE 208
C +GY GT C P E C G RC+ G RC C G+
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEP-CGKGHRCVNSPGSFRCECKTGY------ 388
Query: 209 RDYRTGPCFTQVNNQMCQ---GQLTGIVCTKTL----CCATIG---RAWGHPCE---MCP 255
Y G V+ CQ G+L G C TL C ++G G CE C
Sbjct: 389 --YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 256 AQPQP-------------CRRGF-IPNIRTGACQDVDECQAIPG--ICQGGNCINTVGSF 299
+ P CRRG+ + ++ C+D+DEC G IC CIN GSF
Sbjct: 447 SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSF 505
Query: 300 ECRCP-AGHKQSETTQKCEDIDECSIIPGI--CETGE-CSNTVGSYFCV---CPRGY 349
+C CP +G++ + + C+DIDEC + GI C E C N G + C+ CP Y
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 68.9 bits (167), Expect = 7e-11
Identities = 87/372 (23%), Positives = 142/372 (38%), Gaps = 83/372 (22%)
Query: 2410 CCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
CC DG R HQ + C LP Y T+ + EC+++ C C + +
Sbjct: 36 CCADGHRMATHQKD-CSLP--------------YATESK---ECRMVQEQC----CHSQL 73
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPR-GYVLQEDGK 2528
C T IS + + D C+ +P N + T C C G Q G+
Sbjct: 74 EELHC------ATGISLAN--EQDRCA-TPHGDNASLEATFVKRCCHCCLLGRAAQAQGQ 124
Query: 2529 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGIC 2588
+C+ + + G+ C C+ + E G G
Sbjct: 125 SCE----------------YSLMVGYQCG-----QVFRACCVKSQETGDLDV-----GGL 158
Query: 2589 QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
Q T E ++ + LN D C G C+ C++ C C GY
Sbjct: 159 QETDKIIEVEEEQ----EDPYLN----DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSD 210
Query: 2649 WNQCVDENEC-SNPNACG-SASCYNTLGSYKC----ACPSGFSFDQFSSACHDVNECSSS 2702
C D NEC + ++C SC NT+GS++C +C +G+ + ++C D++EC S
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESG 269
Query: 2703 KNPC--NYGCSNTEGGYLC----GCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENA 2756
+ C ++ C NT G + C C G+ + G+C+ N+ +S +
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCID---INECLSISAPCPIG-HTC 325
Query: 2757 LSPEACYECKIN 2768
++ E Y C+ N
Sbjct: 326 INTEGSYTCQKN 337
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 231 bits (589), Expect = 8e-60
Identities = 132/372 (35%), Positives = 192/372 (51%), Gaps = 38/372 (10%)
Query: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCD----C 1185
C +T C CF GY+ +C D++EC CR G +C+NT GSF+C C
Sbjct: 190 CRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1186 PLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMIGTYQC----SCNPGYQATPDRQG- 1239
G+EL+ C DI+EC + C + C N +G+++C C G+ D G
Sbjct: 249 GTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALGN 305
Query: 1240 CTDIDECMIMNGGCDT--QCTNSEGSYEC-----SCSEGYALMPDGRSCADIDECENNPD 1292
C DI+EC+ ++ C C N+EGSY C +C GY L +G C D+DEC +
Sbjct: 306 CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAE 365
Query: 1293 ICDGG-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICH 1351
C G +C N PG +RC C G+ + C+DVNEC +CENT GS++C
Sbjct: 366 PCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCS 425
Query: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW---IGNGIKCID 1408
C +G+ + C D++EC + C N+ GS++C CR G+ +G+ C D
Sbjct: 426 CSVGFRLSVDGRSCEDINECS----SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 1409 LDECS--NGTHQCSINAQCVNTPGSYRCAC-SEGF--TGDGFTCSDVDECAENINLCE-N 1462
+DEC+ G H CS +C+N PGS++C+C S G+ +G C D+DEC I+ C N
Sbjct: 482 IDECALPTGGHICSY--RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1463 GQCLNVPGAYRC 1474
C N+ G +RC
Sbjct: 540 ETCFNIQGGFRC 551
Score = 221 bits (562), Expect = 1e-56
Identities = 143/424 (33%), Positives = 193/424 (45%), Gaps = 68/424 (16%)
Query: 2215 DECSIGNPCGNGTCTNVIGSFECNCNEGFEP-GPMMNCEDINECAQNPLLCAF--RCMNT 2271
D C G PC C + C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2272 FGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----C 2323
GS+ C +C GY L ED CKD+DEC G+H+C +C+N +G+F C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLP-DFICQNTLGSFRCRPKLQC 294
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICENGR-CVNIIGSYRCE-----CNEGFQSSSSGTE 2377
G + G C+D NEC + C G C+N GSY C+ C G+ + GT
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2378 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2437
C+D + +E C G GH+C PG+ + C
Sbjct: 354 CVDVDE--------------------CAPPAEPC-----GKGHRC--VNSPGSFR----C 382
Query: 2438 PHGPGYTTDGR-----DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL 2492
GY DG D++EC+ P +C NT+GS+ C C VG+ + G SC D+
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2493 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE-DGKTCKDLDEC--QTKQHNCQFLCVN 2549
+ECS S PC+ C N GSYQC C RGY L + DG TC+D+DEC T H C + C+N
Sbjct: 443 NECSSS--PCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 2550 TLGGFTCKCPPG---FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC---ECQRGF 2603
G F C CP + C D +EC + C C N G F C EC +
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Query: 2604 SLDA 2607
A
Sbjct: 561 RRSA 564
Score = 213 bits (541), Expect = 3e-54
Identities = 139/393 (35%), Positives = 185/393 (47%), Gaps = 57/393 (14%)
Query: 2363 CECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQC 2422
C C G+Q S G C D + + + C++ S N V C D G G++
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHS----CRLGESCINTVGSFRCQRDSSCGTGYEL 254
Query: 2423 ELCPLPGTAQYKKICPHGPGYTTDG--RDIDECKV-MPNLCTNGQCINTMGSFRCF---- 2475
T D +DIDEC+ + N + C NT+GSFRC
Sbjct: 255 ---------------------TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 2476 CKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC-----SCPRGYVLQEDGK 2528
CK G+ D G +CID++EC PC + C NTEGSY C +C RGY L E+G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 2529 TCKDLDECQTKQHNCQ--FLCVNTLGGFTCKCPPG--FTQHHTACIDNNECGSQPS-LCG 2583
C D+DEC C CVN+ G F C+C G F C+D NEC P LCG
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 2584 AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGY 2643
K C+NT GS+ C C GF L G +CED++EC + C C N+ G Y+C C +GY
Sbjct: 413 HK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECANVYGSYQCYCRRGY 469
Query: 2644 -IQHYQWNQCVDENECSNPNACGSAS--CYNTLGSYKCACPS-GFSFDQFSSACHDVNEC 2699
+ C D +EC+ P S C N GS++C+CPS G+ C D++EC
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2700 SSSKNPC--NYGCSNTEGGYLC---GCPPGYYR 2727
+ + C N C N +GG+ C CP Y R
Sbjct: 530 VTGIHNCSINETCFNIQGGFRCLAFECPENYRR 562
Score = 211 bits (536), Expect = 1e-53
Identities = 145/414 (35%), Positives = 202/414 (48%), Gaps = 62/414 (14%)
Query: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGR-CFNEIGSFKC 1999
PC C++T C C+ G++L + C D++EC + CR G C N +GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITG-SHSCRLGESCINTVGSFRC 242
Query: 2000 L----CNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCI----CPPGY-EV 2049
C GYELT D +C D +EC + +C P CQN GSFRC C G+ +
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 2050 KSENCIDINECDEDPNICLFG-SCTNTPGGFQCL-----CPPGFVLSDNGRRCFDTRQSF 2103
NCIDINEC C G +C NT G + C C G+ L++ G RC D +
Sbjct: 302 ALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE-- 359
Query: 2104 CFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
C+ P A+ C G G C P +F+ C G+
Sbjct: 360 ---------CAPP-------AEPC-------GKGHRCVNSPG----SFRCECKTGY-YFD 391
Query: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
+ DVNEC PG +C NT GS+ C C +G+ L G C D +ECS +PC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPC 450
Query: 2224 GNGTCTNVIGSFECNCNEGFEPGPM--MNCEDINECA--QNPLLCAFRCMNTFGSYECTC 2279
C NV GS++C C G++ + + CEDI+ECA +C++RC+N GS++C+C
Sbjct: 451 SQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSC 509
Query: 2280 P-IGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMAR 2329
P GY L + + C+D+DEC G+H+C S C N+ G F C+ CP R
Sbjct: 510 PSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (528), Expect = 9e-53
Identities = 177/614 (28%), Positives = 242/614 (39%), Gaps = 122/614 (19%)
Query: 1166 PLLCRGGTC-----VNTEGSFQCDCPLGHELSPSREDC-----VDINECSLSDNLCRNGK 1215
PLL GG V+ + + C GH ++ ++DC + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG-GCDTQCTNSEGSYECSCSEGYAL 1274
C + + C+ DR C +G + T + C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDR--------CATPHGDNASLEATFVKRCCHC-CLLGRAA 119
Query: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYD---------GFMASMDMKTCID 1325
G+SC + G QC + +R C G + D ++
Sbjct: 120 QAQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVE 168
Query: 1326 VNECD--LNSNICMFG-----ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC 1378
+ D LN C G +C +T +C C +GY + C DV+EC G+H+C
Sbjct: 169 EEQEDPYLNDR-CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1379 DMHASCLNIPGSFKC----SCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
+ SC+N GSF+C SC G+ + C D+DEC +G H C + C NT GS+R
Sbjct: 228 RLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 1434 C----ACSEGFTGDGF-TCSDVDECAENINLCENGQ-CLNVPGAYRCE-----CEMGFTP 1482
C C GF D C D++EC C G C+N G+Y C+ C G+
Sbjct: 288 CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 1483 ASDSRSCQDIDECS-FQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD-P 1539
+ C D+DEC+ C G C N PG F C C GY D C D++EC P
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYP 407
Query: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
C NT G Y C+C F+L+ G C D + C S C+ E
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCED--INEC---------SSSPCSQECAN 456
Query: 1600 GVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
C C G Y L + + EDIDEC
Sbjct: 457 VYGSYQCYCRRG------------------YQL--------SDVDGVTCEDIDEC----A 486
Query: 1660 LCQGGN-----CINTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTL 1712
L GG+ CIN GSFQC CP GY L+ + R C+DIDEC C TC+N
Sbjct: 487 LPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQ 546
Query: 1713 GNYTCI---CPPEY 1723
G + C+ CP Y
Sbjct: 547 GGFRCLAFECPENY 560
Score = 204 bits (518), Expect = 1e-51
Identities = 136/408 (33%), Positives = 186/408 (45%), Gaps = 61/408 (14%)
Query: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC-- 2321
C +C +T C+C +GY L D C+D++EC G H C G C N +G+F C
Sbjct: 186 CKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL-GESCINTVGSFRCQR 244
Query: 2322 --ICPPGMARRPDGEGCVDENECRTKPGIC-ENGRCVNIIGSYRC----ECNEGFQSSSS 2374
C G D C D +EC + C + C N +GS+RC +C GF +
Sbjct: 245 DSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 2375 GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYK 2434
G C+D + L + C + GH C T Q K
Sbjct: 304 GN-CIDINECLS----ISAPCPI---------------------GHTCINTEGSYTCQ-K 336
Query: 2435 KICPHGPGYTTDGR-----DIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTS 2488
+ G GY + D+DEC C G +C+N+ GSFRC CK GY D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2489 CIDLDECSQSP-KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLC 2547
C+D++EC + P + C + C+NT GSY CSC G+ L DG++C+D++EC + C C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQEC 454
Query: 2548 VNTLGGFTCKCPPGFTQHHT---ACIDNNECGSQPS--LCGAKGICQNTPGSFSCEC-QR 2601
N G + C C G+ C D +EC +C + C N PGSF C C
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR--CINIPGSFQCSCPSS 512
Query: 2602 GFSLDATGLNCEDVDEC-DGNHRCQ--HGCQNILGGYRC---GCPQGY 2643
G+ L G NC+D+DEC G H C C NI GG+RC CP+ Y
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 196 bits (497), Expect = 4e-49
Identities = 124/364 (34%), Positives = 170/364 (46%), Gaps = 48/364 (13%)
Query: 2412 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT--TDG---RDIDECKVMPNLCTNGQ-C 2465
C GG QC + +C GY +DG D++EC + C G+ C
Sbjct: 180 CRGGGPCKQQCR------DTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESC 233
Query: 2466 INTMGSFRC----FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC---- 2515
INT+GSFRC C GY SC D+DEC C ++IC+NT GS++C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCK-----CPPGF--TQHH 2566
C G++ G C D++EC + C C+NT G +TC+ C G+ +
Sbjct: 293 QCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 2567 TACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD--GNHRC 2624
T C+D +EC CG C N+PGSF CEC+ G+ D C DV+EC C
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 2625 QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGF 2684
H C+N LG Y C C G+ C D NECS+ + C S C N GSY+C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-SPC-SQECANVYGSYQCYCRRGY 469
Query: 2685 SF-DQFSSACHDVNECS--SSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG--------HC 2733
D C D++EC+ + + C+Y C N G + C CP YR+ C
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 2734 VSGM 2737
V+G+
Sbjct: 530 VTGI 533
Score = 194 bits (493), Expect = 1e-48
Identities = 135/401 (33%), Positives = 185/401 (46%), Gaps = 58/401 (14%)
Query: 970 RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAV 1029
+C ++ C C G L G C D+ +ECI ++C V
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDV-----------NECITGSHSCRLGESCINTV 237
Query: 1030 GAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK- 1088
G+ C+ GT G LT KDI+EC++ C
Sbjct: 238 GSF---RCQRDSSCGT----------------GYELTEDNSCKDIDECESGIHNCLPDFI 278
Query: 1089 CRNTIGSFKCR----CNSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFECE-- 1141
C+NT+GSF+CR C SGF D NC DI+EC C G C+NT GS+ C+
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 1142 ---CFEGY---ESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQCDCPLGHELSPS 1194
C GY E G C+D+DEC C +G CVN+ GSF+C+C G+
Sbjct: 338 VPNCGRGYHLNEEG----TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD 1254
CVD+NEC KC N +G+Y CSC+ G++ + D + C DI+EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCS 451
Query: 1255 TQCTNSEGSYECSCSEGYALMP-DGRSCADIDEC--ENNPDICDGGQCTNIPGEYRCLC- 1310
+C N GSY+C C GY L DG +C DIDEC IC +C NIPG ++C C
Sbjct: 452 QECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCP 510
Query: 1311 YDGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFIC 1350
G+ + + + C D++EC + C E C N +G F C
Sbjct: 511 SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 194 bits (492), Expect = 1e-48
Identities = 138/435 (31%), Positives = 197/435 (45%), Gaps = 70/435 (16%)
Query: 1803 TGKAVDIDECKEIPGI---CANG-----VCINQIGSFRCECPTGFSYNDLLLVCEDIDEC 1854
T K ++++E +E P + C G C + C C G+ + CED++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 1855 SNGDNLCQRNADCINSPGSYRCE----CAAGFKLSPNGACVDRNECLE-IPNVCSHGLCV 1909
G + C+ CIN+ GS+RC+ C G++L+ + +C D +EC I N +C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 1910 DLQGSYQCI----CHNGFKASQDQT-MCMDVDECER--HPCGNG-TCKNTVGSYNCL--- 1958
+ GS++C C +GF QD C+D++EC PC G TC NT GSY C
Sbjct: 281 NTLGSFRCRPKLQCKSGF--IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 1959 --CYPGFELTHNND-CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI 2015
C G+ L C+D+DEC+ + RC N GSF+C C GY + C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGY--EVKSENCIDINECDEDPNICLFGSCT 2073
D NEC PG C+N GS+ C C G+ V +C DINEC P C
Sbjct: 399 DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP---CSQECA 455
Query: 2074 NTPGGFQCLCPPGFVLSD-NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMP 2132
N G +QC C G+ LSD +G C D +C++P + +C +P
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDI-----------DECALPTGGHICSYRCI--NIP 502
Query: 2133 GEGWGDPCELCPKDDEVAFQDLCP-YGHGTVPSLHDTREDVNECLESPGICS-NGQCINT 2190
G +FQ CP G+ P+ + +D++EC+ CS N C N
Sbjct: 503 G----------------SFQCSCPSSGYRLAPNGRNC-QDIDECVTGIHNCSINETCFNI 545
Query: 2191 DGSFRC---ECPMGY 2202
G FRC ECP Y
Sbjct: 546 QGGFRCLAFECPENY 560
Score = 184 bits (467), Expect = 1e-45
Identities = 130/381 (34%), Positives = 174/381 (45%), Gaps = 67/381 (17%)
Query: 493 QTIDICKHHANLCLNGR-CIPTVSSYRCE----CNMGYKQDANGDCIDVDECTS---NPC 544
+ ++ C ++ C G CI TV S+RC+ C GY+ + C D+DEC S N
Sbjct: 215 EDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 545 TNGDCVNTPGSYYCK----CHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTDGSFQ 599
+ C NT GS+ C+ C +GF + CIDI+EC+ C G C+NT+GS+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT 333
Query: 600 C-----ICNAGFELTTDGKNCVDHDECT-TTNMCLNG-MCINEDGSFKCICKPGFVLAPN 652
C C G+ L +G CVD DEC C G C+N GSF+C CK G+
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 653 GRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
R C DV+ECQ PG C N+ GS+ C C G + +DGR C D
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDI----------- 442
Query: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT-VDG---R 767
+EC PC A + C G ++ VDG
Sbjct: 443 --------------NECS--------SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 768 DINECALDP--DICANGICENLRGSYRCNC-NSGYEPDASGRNCIDIDECLVNRLLCD-N 823
DI+ECAL IC+ C N+ GS++C+C +SGY +GRNC DIDEC+ C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 824 GLCRNTPGSYSC---TCPPGY 841
C N G + C CP Y
Sbjct: 540 ETCFNIQGGFRCLAFECPENY 560
Score = 170 bits (430), Expect = 2e-41
Identities = 135/409 (33%), Positives = 177/409 (43%), Gaps = 73/409 (17%)
Query: 537 DECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR-CVNTD 595
D C C +T C C G+Q +C D++ECI C+ G C+NT
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 596 GSFQC----ICNAGFELTTDGKNCVDHDECTT-TNMCL-NGMCINEDGSFKCI----CKP 645
GSF+C C G+ELT D +C D DEC + + CL + +C N GSF+C CK
Sbjct: 238 GSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 646 GFVLAPNGRYCTDVDECQTPGI-CMNGH-CINSEGSFRC-----DCPPGLAVGMDGRVCV 698
GF+ G C D++EC + C GH CIN+EGS+ C +C G + +G CV
Sbjct: 297 GFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 699 DTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSS 758
D EC G G C P E C +
Sbjct: 356 DV-------------------------DECAPPAEPCGKGHRCVNSPGSFRCE----CKT 386
Query: 759 GV---GITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL 815
G GI+ D+NEC P CEN GSY C+C+ G+ GR+C DI+EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 816 VNRLLCDNGLCRNTPGSYSCTCPPGY-VFRTETETCEDINEC---ESNPCVNGACRNNLG 871
+ + C N GSY C C GY + + TCEDI+EC + C N G
Sbjct: 447 SSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 872 SFNCEC-SPGSKLSSTGLICID-----------SLKGTCWLNIQDS-RC 907
SF C C S G +L+ G C D S+ TC+ NIQ RC
Sbjct: 504 SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRC 551
Score = 164 bits (416), Expect = 9e-40
Identities = 135/444 (30%), Positives = 187/444 (42%), Gaps = 91/444 (20%)
Query: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHC----IC 1517
QC + C C +G+ SD SC+D++EC + + C G +C N G F C C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSC 248
Query: 1518 DDGYELDRTGGNCTDIDECADPI-NCV-NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNR 1575
GYEL +C DIDEC I NC+ + +C NT G + C P Q G + +
Sbjct: 249 GTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQCKS---GFIQDA 302
Query: 1576 VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPG 1635
+GNC + N + + S C +G TC +N+ YT
Sbjct: 303 LGNC-----------IDINECLSI-----SAPCPIG-------HTC--INTEGSYTCQKN 337
Query: 1636 ----GEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
G G+ N D+DEC C +G C+N+ GSF+CEC GYY +R+C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 1691 EDIDECFAHPG-VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
D++EC +PG +CG C NTLG+Y C C + G +C D+ + + + C
Sbjct: 398 VDVNECQRYPGRLCG-HKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC------SSSPC 450
Query: 1750 ENELPFNVTKRMCCCT--YNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV 1807
E C C Y + CE
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCE------------------------------ 480
Query: 1808 DIDECKEIPG--ICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
DIDEC G IC+ CIN GSF+C CP +G+ C+DIDEC G + C N
Sbjct: 481 DIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1865 ADCINSPGSYRC---ECAAGFKLS 1885
C N G +RC EC ++ S
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRS 563
Score = 157 bits (397), Expect = 1e-37
Identities = 174/605 (28%), Positives = 234/605 (38%), Gaps = 128/605 (21%)
Query: 592 VNTDGSFQCICNAGFELTTDGKNC-----VDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
V+ D + C G + T K+C + EC M C ++ C G
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKEC---RMVQEQCCHSQLEELHCAT--G 81
Query: 647 FVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF--RCD--CPPGLAVGMDGRVCVDTHM 702
LA + D C TP +G + E +F RC C G A G+ C + M
Sbjct: 82 ISLA------NEQDRCATP----HGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLM 131
Query: 703 RSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGI 762
G + + CV+ S E L G+
Sbjct: 132 VGYQCGQVFRACCVK-------------------------------SQETGDLDVGGLQE 160
Query: 763 TVDGRDINECALDP---DICANG-----ICENLRGSYRCNCNSGYEPDASGRNCIDIDEC 814
T ++ E DP D C G C + C+C GY+ + G +C D++EC
Sbjct: 161 TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 815 LVNRLLCDNG-LCRNTPGSYSC----TCPPGYVFRTETETCEDINECES---NPCVNGAC 866
+ C G C NT GS+ C +C GY TE +C+DI+ECES N + C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFIC 279
Query: 867 RNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGA 926
+N LGSF C KL D+L G C ++IN S C
Sbjct: 280 QNTLGSFRCR----PKLQCKSGFIQDAL-GNC----------IDINECLSISAPCPI--- 321
Query: 927 AWGSPCERCELDTACPRGLARI--------KGVTCEDVNECEVFPGVCPNG-RCVNSKGS 977
G C E C + + +G C DV+EC C G RCVNS GS
Sbjct: 322 --GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Query: 978 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG---AAWG 1034
F CEC G DG R+C+D+ Q Y C H C C+VG + G
Sbjct: 380 FRCECKTGYYFDGISRMCVDVNECQRY---PGRLCGHKCENTLGSYLCSCSVGFRLSVDG 436
Query: 1035 TECE---ECPK-PGTKE-------YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG- 1082
CE EC P ++E Y+ C RG ++ V +DI+EC G
Sbjct: 437 RSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC-----EDIDECALPTGG 491
Query: 1083 -MCTYGKCRNTIGSFKCRC-NSGFALDMEERNCTDIDECRISPDLCG-SGICVNTPGSFE 1139
+C+Y +C N GSF+C C +SG+ L RNC DIDEC C + C N G F
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFR 550
Query: 1140 CECFE 1144
C FE
Sbjct: 551 CLAFE 555
Score = 144 bits (363), Expect = 1e-33
Identities = 118/398 (29%), Positives = 172/398 (43%), Gaps = 86/398 (21%)
Query: 273 ACQDVDECQAIPGICQ-GGNCINTVGSFECR----CPAGHKQSETTQKCEDIDEC-SIIP 326
+C+DV+EC C+ G +CINTVGSF C+ C G++ +E C+DIDEC S I
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIH 271
Query: 327 GICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM 386
C NT+GS+ RC + C SG + Q+ G
Sbjct: 272 NCLPDFICQNTLGSF---------------RCRPKL--QCKSGFI-----QDALGN---- 305
Query: 387 QCCCEPGRCWGIGTIPEACPVRGS---EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFA 443
C + C I CP+ + E C +P
Sbjct: 306 --CIDINECLSISA---PCPIGHTCINTEGSYTCQKNVPN-------------------- 340
Query: 444 PSGNGNGYGPGGTGFIPI--------PGGNGF----SPGVGGAGVGAGGQGPIITGLTIL 491
G G GT + + P G G SPG G G++ +
Sbjct: 341 -CGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYY---FDGISRM 396
Query: 492 NQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCV 550
++ C+ + +C T+ SY C C++G++ +G C D++EC+S+PC+ +C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ-ECA 455
Query: 551 NTPGSYYCKCHAGFQRTPTK-QACIDIDECI--QNGVLCKNGRCVNTDGSFQCIC-NAGF 606
N GSY C C G+Q + C DIDEC G +C + RC+N GSFQC C ++G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGY 514
Query: 607 ELTTDGKNCVDHDECTT--TNMCLNGMCINEDGSFKCI 642
L +G+NC D DEC T N +N C N G F+C+
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 99.0 bits (245), Expect = 6e-20
Identities = 99/327 (30%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 97 CCPGWKTLPGG------NQCIV--------PICRNSCGDGFCSRPNMCTCSSGQISSTCG 142
C G++ L G N+CI C N+ G C R + C + +++
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCG-TGYELTEDNS 259
Query: 143 SKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNG------GRCIGPNRC 196
K I +C N C D CQ +G++ +P + C++G G CI N C
Sbjct: 260 CKDIDECESGIHN---CLPDFI-CQNT-LGSFRCRPKLQ--CKSGFIQDALGNCIDINEC 312
Query: 197 A-----CVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLT--GIVCTKTLCCATIGRAWG- 248
C G T E Y C V N L G C CA G
Sbjct: 313 LSISAPCPIGHTCINTEGSYT---CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK 369
Query: 249 -HPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
H C P + C+ G+ + + C DV+ECQ PG G C NT+GS+ C C G
Sbjct: 370 GHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVG 429
Query: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY-VTSTDGSRC--IDQRT 363
+ S + CEDI+ECS P C EC+N GSY C C RGY ++ DG C ID+
Sbjct: 430 FRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 364 GMCFSGLVNGRCAQELPGRMTKMQCCC 390
+ + RC +PG QC C
Sbjct: 487 LPTGGHICSYRCI-NIPG---SFQCSC 509
Score = 94.4 bits (233), Expect = 2e-18
Identities = 81/299 (27%), Positives = 113/299 (37%), Gaps = 66/299 (22%)
Query: 152 RCMNGGTCADDHCQCQKGYIGTYC----GQPVCENG--CQNGGRCI-GPNRC----ACVY 200
RC GG C QC+ C G + +G C++ CI G + C +C+
Sbjct: 179 RCRGGGPCKQ---QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 201 GFTGPQCERDYRTGP---------------CFTQVNNQM----CQGQLTGIVCTKTLCCA 241
+C+RD G C + ++N + CQ L C L C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCK 295
Query: 242 T--IGRAWGH------------PCEM------------CPAQPQPCRRGFIPNIRTGACQ 275
+ I A G+ PC + C C RG+ N C
Sbjct: 296 SGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV 355
Query: 276 DVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGEC 334
DVDEC C +G C+N+ GSF C C G+ ++ C D++EC PG +C
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
NT+GSY C C G+ S DG C D + + C+QE QC C G
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCED------INECSSSPCSQECANVYGSYQCYCRRG 468
Score = 87.8 bits (216), Expect = 1e-16
Identities = 95/297 (31%), Positives = 125/297 (42%), Gaps = 75/297 (25%)
Query: 114 ICRNSCGDGFCSRPNMCTCSSGQISSTCGSK-SIQQC---SVRCMNGGTCADDH----CQ 165
IC+N+ G C RP + C SG I G+ I +C S C G TC + CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 166 -----CQKGYI----GTYCGQ-----PVCENGCQNGGRCI---GPNRCACVYGFTGPQCE 208
C +GY GT C P E C G RC+ G RC C G+
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEP-CGKGHRCVNSPGSFRCECKTGY------ 388
Query: 209 RDYRTGPCFTQVNNQMCQ---GQLTGIVCTKTL----CCATIG---RAWGHPCE---MCP 255
Y G V+ CQ G+L G C TL C ++G G CE C
Sbjct: 389 --YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS 446
Query: 256 AQPQP-------------CRRGF-IPNIRTGACQDVDECQAIPG--ICQGGNCINTVGSF 299
+ P CRRG+ + ++ C+D+DEC G IC CIN GSF
Sbjct: 447 SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSF 505
Query: 300 ECRCP-AGHKQSETTQKCEDIDECSIIPGI--CETGE-CSNTVGSYFCV---CPRGY 349
+C CP +G++ + + C+DIDEC + GI C E C N G + C+ CP Y
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 68.9 bits (167), Expect = 7e-11
Identities = 87/372 (23%), Positives = 142/372 (38%), Gaps = 83/372 (22%)
Query: 2410 CCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
CC DG R HQ + C LP Y T+ + EC+++ C C + +
Sbjct: 36 CCADGHRMATHQKD-CSLP--------------YATESK---ECRMVQEQC----CHSQL 73
Query: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPR-GYVLQEDGK 2528
C T IS + + D C+ +P N + T C C G Q G+
Sbjct: 74 EELHC------ATGISLAN--EQDRCA-TPHGDNASLEATFVKRCCHCCLLGRAAQAQGQ 124
Query: 2529 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGIC 2588
+C+ + + G+ C C+ + E G G
Sbjct: 125 SCE----------------YSLMVGYQCG-----QVFRACCVKSQETGDLDV-----GGL 158
Query: 2589 QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQ 2648
Q T E ++ + LN D C G C+ C++ C C GY
Sbjct: 159 QETDKIIEVEEEQ----EDPYLN----DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSD 210
Query: 2649 WNQCVDENEC-SNPNACG-SASCYNTLGSYKC----ACPSGFSFDQFSSACHDVNECSSS 2702
C D NEC + ++C SC NT+GS++C +C +G+ + ++C D++EC S
Sbjct: 211 GVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESG 269
Query: 2703 KNPC--NYGCSNTEGGYLC----GCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENA 2756
+ C ++ C NT G + C C G+ + G+C+ N+ +S +
Sbjct: 270 IHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCID---INECLSISAPCPIG-HTC 325
Query: 2757 LSPEACYECKIN 2768
++ E Y C+ N
Sbjct: 326 INTEGSYTCQKN 337
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 228 bits (581), Expect = 7e-59
Identities = 141/414 (34%), Positives = 200/414 (48%), Gaps = 54/414 (13%)
Query: 1200 DINECSLSDNLCR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDEC-MIMNGGCDTQC 1257
D++EC+ + C + C N +Y+CSC PGYQ + + C DIDEC +NGGC C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQG--EGRQCEDIDECGNELNGGCVHDC 102
Query: 1258 TNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMAS 1317
N G+Y C+C +G+ L DG +C D+DEC N C C N+ G Y C C +GF S
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLS 161
Query: 1318 MDMKTCIDVNECDLN--------SNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVD 1369
+ TCI +E L+ S+IC E +GS C C+ G+ + K C +
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICK----EAPRGSVACECRPGFELAKNQRDC--IL 215
Query: 1370 ECEIGAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCIDLDEC------SNGT----- 1416
C G C SC + +CSC + +G C++ ++ SN T
Sbjct: 216 TCNHGNGGCQH--SCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDG 273
Query: 1417 ----------HQCSIN-----AQCVNTPGSYRCACSEGFTG--DGFTCSDVDECAENINL 1459
C++N C +T C+C GFT DG TC D+DEC
Sbjct: 274 DKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGG 333
Query: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
C++ C N+ G++ C C+ GF +D +SCQD+DECS C +C N PG F C C+
Sbjct: 334 CDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNR 391
Query: 1520 GYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
GY L +C D +EC+ +CVNT G YEC C P ++L+ CV+
Sbjct: 392 GYTLYGFT-HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 214 bits (544), Expect = 1e-54
Identities = 140/445 (31%), Positives = 192/445 (43%), Gaps = 86/445 (19%)
Query: 2252 EDINECAQNPLLCAFR--CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL-----HD 2304
ED++ECAQ C C NT SY+C+C GY + + + C+D+DEC L HD
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGEGRQCEDIDECGNELNGGCVHD 101
Query: 2305 CESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCE 2364
C N+ G + C C G DG C+D +EC G C++ CVN++GSY C
Sbjct: 102 C-------LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECC 153
Query: 2365 CNEGFQSSSSGTECLD-NRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCE 2423
C EGF S + C+ + +GL C + G H C+
Sbjct: 154 CKEGFFLSDNQHTCIHRSEEGLS------------------------CMNKDHGCSHICK 189
Query: 2424 LCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG---QCINTMGSFRCFCKVGY 2480
P A C PG+ ++ +C + N G C +T C C Y
Sbjct: 190 EAPRGSVA-----CECRPGFEL-AKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQY 243
Query: 2481 TTDISGTSCID----------------------------LDECSQSPKPCNYICKNTEGS 2512
G SC++ ++ C+ + C+ CK+T
Sbjct: 244 KMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTG 303
Query: 2513 YQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACI 2570
CSCP G+ LQ DGKTCKD+DECQT+ C C N +G F C C GF +C
Sbjct: 304 VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQ 363
Query: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHGCQ 2629
D +EC S C C N PG+F+C C RG++L +C D +EC N CQ C
Sbjct: 364 DVDEC-SLDRTCDHS--CINHPGTFACACNRGYTLYGF-THCGDTNECSINNGGCQQVCV 419
Query: 2630 NILGGYRCGCPQGYIQHYQWNQCVD 2654
N +G Y C C GY H+ CV+
Sbjct: 420 NTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 206 bits (523), Expect = 4e-52
Identities = 135/412 (32%), Positives = 192/412 (46%), Gaps = 19/412 (4%)
Query: 1892 DRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGT--C 1948
D +EC + + C + LC + SY+C C G++ Q C D+DEC G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVHDC 102
Query: 1949 KNTVGSYNCLCYPGFELTHN-NDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYEL 2007
N G+Y C C+ GF L H+ ++CLD+DEC G C++ C N +GS++C C EG+ L
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGG-CQH-TCVNVMGSYECCCKEGFFL 160
Query: 2008 TPDGKNCIDTNE----CVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDED 2063
+ + CI +E C+ CS + GS C C PG+E+ I C+
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHG 220
Query: 2064 PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTK 2123
C SC +T G +C C P + + +GR C + R+ E+ SV K
Sbjct: 221 NGGCQH-SCDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTESNTTSVVDGDKRVK 278
Query: 2124 AKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICS 2183
+ G C+ KD CP G T+ T +D++EC G C
Sbjct: 279 RRLLMETCAVNNGG--CDRTCKDTSTGVHCSCPVGF-TLQLDGKTCKDIDECQTRNGGCD 335
Query: 2184 NGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGF 2243
+ C N GSF C C G+ L C D DECS+ C + +C N G+F C CN G+
Sbjct: 336 HF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGY 393
Query: 2244 EPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDL 2295
+C D NEC+ N C C+NT GSYEC C GY L ++K C ++
Sbjct: 394 TLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 186 bits (473), Expect = 2e-46
Identities = 125/414 (30%), Positives = 176/414 (42%), Gaps = 51/414 (12%)
Query: 1158 DIDECERNPLLCRGGT-CVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKC 1216
D+DEC + C C NT S++C C G++ C DI+EC N C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDC 102
Query: 1217 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 1276
+N+ G Y+C+C G+ D C D+DEC+ NGGC C N GSYEC C EG+ L
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSD 162
Query: 1277 DGRSCADIDE----CENNPDICDGGQCTNIP-GEYRCLCYDGFMASMDMKTCIDVNECDL 1331
+ +C E C N C C P G C C GF + + + CI C+
Sbjct: 163 NQHTCIHRSEEGLSCMNKDHGCSH-ICKEAPRGSVACECRPGFELAKNQRDCILT--CNH 219
Query: 1332 NSNICMFGECENTKGSFICHCQLGYSV------------------KKGTTGCTDVDE--- 1370
+ C C++T C C Y + + TT D D+
Sbjct: 220 GNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVK 278
Query: 1371 -------CEIGAHNCDMHASCLNIPGSFKCSCREGWIG--NGIKCIDLDECSNGTHQCSI 1421
C + CD +C + CSC G+ +G C D+DEC C
Sbjct: 279 RRLLMETCAVNNGGCDR--TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-- 334
Query: 1422 NAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMG 1479
+ C N GS+ C C +GF D +C DVDEC+ + C++ C+N PG + C C G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCDHS-CINHPGTFACACNRG 392
Query: 1480 FTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDI 1533
+T + C D +ECS N C N G + C C GY+L +C ++
Sbjct: 393 YTLYGFTH-CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 185 bits (469), Expect = 6e-46
Identities = 130/416 (31%), Positives = 188/416 (45%), Gaps = 29/416 (6%)
Query: 1367 DVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCV 1426
DVDEC G +C A C N P S+KCSC+ G+ G G +C D+DEC N + ++ C+
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVH-DCL 103
Query: 1427 NTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPAS 1484
N PG+YRC C +GF DG C DVDEC EN C++ C+NV G+Y C C+ GF +
Sbjct: 104 NIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSD 162
Query: 1485 DSRSCQDIDE----CSFQNICVFGTCNNLP-GMFHCICDDGYELDRTGGNCTDIDECADP 1539
+ +C E C ++ C P G C C G+EL + +C I C
Sbjct: 163 NQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNHG 220
Query: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGS-LSCNTEIG 1598
C +T EC+C P ++++ G C++ + L+ S + + +
Sbjct: 221 NGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLERE--DTVLEVTESNTTSVVDGDKRVK 278
Query: 1599 VGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELP 1658
+ +C + G C+ ST + CP G + + T +DIDECQ
Sbjct: 279 RRLLMETCAVNNG-----GCDRTCKDTSTGVHCSCPVGFTLQLDGKT--CKDIDECQTRN 331
Query: 1659 GLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCI 1718
G C C N GSF C C +G+ L D + C+D+DEC + C +C N G + C
Sbjct: 332 GGCD-HFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-SLDRTC-DHSCINHPGTFACA 388
Query: 1719 CPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNK 1774
C Y + G +C D + S N C+ V C C WNK
Sbjct: 389 CNRGY-TLYGFTHCGDTNEC----SINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 184 bits (467), Expect = 1e-45
Identities = 130/440 (29%), Positives = 176/440 (40%), Gaps = 77/440 (17%)
Query: 2324 PPGMARRPDGEGCVDENECRTKPGICE-NGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
PPG R + VDE C C + C N SY+C C G+Q E +D
Sbjct: 33 PPGRGRAAGPQEDVDE--CAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDID-- 88
Query: 2383 QGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG 2442
EC + G H C +PG Y+ C G
Sbjct: 89 --------------------------ECGNELNGGCVHDC--LNIPGN--YRCTCFDGFM 118
Query: 2443 YTTDGR---DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDE----C 2495
DG D+DEC C + C+N MGS+ C CK G+ + +CI E C
Sbjct: 119 LAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSC 177
Query: 2496 SQSPKPCNYICKNT-EGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
C++ICK GS C C G+ L ++ + C + C CQ C +T G
Sbjct: 178 MNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGP 235
Query: 2555 TCKCPPGFTQHH--------------------TACIDNNECGSQPSLC--------GAKG 2586
C C P + H T+ +D ++ + L G
Sbjct: 236 ECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR 295
Query: 2587 ICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG-NHRCQHGCQNILGGYRCGCPQGYIQ 2645
C++T C C GF+L G C+D+DEC N C H C+NI+G + CGC +G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKL 355
Query: 2646 HYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNP 2705
C D +ECS C SC N G++ CAC G++ F+ C D NECS +
Sbjct: 356 LTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGFTH-CGDTNECSINNGG 413
Query: 2706 CNYGCSNTEGGYLCGCPPGY 2725
C C NT G Y C C PGY
Sbjct: 414 CQQVCVNTVGSYECQCHPGY 433
Score = 182 bits (462), Expect = 4e-45
Identities = 136/429 (31%), Positives = 181/429 (42%), Gaps = 88/429 (20%)
Query: 529 ANGDCIDVDECTS--NPC-TNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVL 585
A G DVDEC + C + C NTP SY C C G+Q + C DIDEC
Sbjct: 39 AAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNE--- 93
Query: 586 CKNGRCV----NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKC 641
NG CV N G+++C C GF L DG NC+D DEC N C+N GS++C
Sbjct: 94 -LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYEC 152
Query: 642 ICKPGFVLAPNGRYCTDVDECQTPGICMN-----GHCINS--EGSFRCDCPPGLAVGMDG 694
CK GF L+ N C + + CMN H GS C+C PG + +
Sbjct: 153 CCKEGFFLSDNQHTC--IHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQ 210
Query: 695 RVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF---GEPC---------- 741
R C+ TC G G C EC C +P Y G C
Sbjct: 211 RDCI-----LTCNHG--NGGCQHSCDDTADGPECSC-HPQYKMHTDGRSCLEREDTVLEV 262
Query: 742 ---------------------QPCPAKN----------SAEFHGLCSSGVGITVDG---R 767
+ C N S H C G + +DG +
Sbjct: 263 TESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCK 322
Query: 768 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR 827
DI+EC C + C+N+ GS+ C C G++ ++C D+DEC ++R CD+ C
Sbjct: 323 DIDECQTRNGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDR-TCDHS-CI 379
Query: 828 NTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACR----NNLGSFNCECSPGSKL 883
N PG+++C C GY T C D NEC N NG C+ N +GS+ C+C PG KL
Sbjct: 380 NHPGTFACACNRGYTLYGFTH-CGDTNECSIN---NGGCQQVCVNTVGSYECQCHPGYKL 435
Query: 884 SSTGLICID 892
C++
Sbjct: 436 HWNKKDCVE 444
Score = 173 bits (439), Expect = 2e-42
Identities = 136/450 (30%), Positives = 191/450 (42%), Gaps = 86/450 (19%)
Query: 1804 GKAVDIDECKEIPGIC-ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDN-LC 1861
G D+DEC + C A+ +C N S++C C G+ CEDIDEC N N C
Sbjct: 41 GPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGC 98
Query: 1862 QRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICH 1920
DC+N PG+YRC C GF L+ +G C+D +ECLE C H CV++ GSY+C C
Sbjct: 99 VH--DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCK 155
Query: 1921 NGFKASQDQTMCMDVDE----C--ERHPCGNGTCKNTVGSYNCLCYPGFELTHN-NDCLD 1973
GF S +Q C+ E C + H C + + GS C C PGFEL N DC
Sbjct: 156 EGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC-- 213
Query: 1974 IDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE-------------- 2019
I C+ G C++ C + +C C+ Y++ DG++C++ +
Sbjct: 214 ILTCNHGNGG-CQHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVV 271
Query: 2020 --------------CVALPGSCSPGTCQNLEGSFRCICPPGY--EVKSENCIDINECDED 2063
C G C TC++ C CP G+ ++ + C DI+EC
Sbjct: 272 DGDKRVKRRLLMETCAVNNGGCD-RTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTR 330
Query: 2064 PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTK 2123
C C N G F C C GF L + + C D +CS+ + + +
Sbjct: 331 NGGC-DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV-----------DECSLDRTCDHS- 377
Query: 2124 AKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICS 2183
C PG F C G+ H D NEC + G C
Sbjct: 378 ----CINHPG----------------TFACACNRGYTLYGFTH--CGDTNECSINNGGCQ 415
Query: 2184 NGQCINTDGSFRCECPMGYNLDYTGVRCVD 2213
C+NT GS+ C+C GY L + CV+
Sbjct: 416 Q-VCVNTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 172 bits (436), Expect = 4e-42
Identities = 107/361 (29%), Positives = 149/361 (41%), Gaps = 47/361 (13%)
Query: 2412 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNGQCINT 2468
C G H LC T+ YK C PGY +GR DIDEC N C+N
Sbjct: 49 CAQGLDDCHADALCQNTPTS-YKCSCK--PGYQGEGRQCEDIDECGNELNGGCVHDCLNI 105
Query: 2469 MGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
G++RC C G+ G +C+D+DEC ++ C + C N GSY+C C G+ L ++
Sbjct: 106 PGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQH 165
Query: 2529 TCKDLDE----CQTKQHNCQFLCVNT-LGGFTCKCPPGF--TQHHTACIDNNECGSQPSL 2581
TC E C K H C +C G C+C PGF ++ CI G+
Sbjct: 166 TCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNG--- 222
Query: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-------------DGNHR----- 2623
G + C +T C C + + G +C + ++ DG+ R
Sbjct: 223 -GCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRL 281
Query: 2624 -----------CQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNT 2672
C C++ G C CP G+ C D +EC N C N
Sbjct: 282 LMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNI 341
Query: 2673 LGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGH 2732
+GS+ C C GF +C DV+ECS + C++ C N G + C C GY G H
Sbjct: 342 VGSFDCGCKKGFKLLTDEKSCQDVDECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTH 400
Query: 2733 C 2733
C
Sbjct: 401 C 401
Score = 170 bits (430), Expect = 2e-41
Identities = 124/425 (29%), Positives = 184/425 (43%), Gaps = 42/425 (9%)
Query: 1973 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECV-ALPGSCSPGT 2031
D+DEC+ + C N S+KC C GY+ +G+ C D +EC L G C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD- 101
Query: 2032 CQNLEGSFRCICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVL 2089
C N+ G++RC C G+ + + NC+D++EC E+ C +C N G ++C C GF L
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 2090 SDNGRRCFD-TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDE 2148
SDN C + + N ++G + K + C PG EL +
Sbjct: 161 SDNQHTCIHRSEEGLSCMNKDHGCSHICK--EAPRGSVACECRPG------FELAKNQRD 212
Query: 2149 VAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGS--FRCECPMGYNLDY 2206
C +G+G D D EC C ++TDG E + +
Sbjct: 213 CILT--CNHGNGGCQHSCDDTADGPECS-----CHPQYKMHTDGRSCLEREDTVLEVTES 265
Query: 2207 TGVRCVDTDE----------CSIGNPCGNGTCTNVIGSFECNCNEGFEPG-PMMNCEDIN 2255
VD D+ C++ N + TC + C+C GF C+DI+
Sbjct: 266 NTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDID 325
Query: 2256 ECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNL 2315
EC C C N GS++C C G+ L D+K C+D+DEC+ C+ C N
Sbjct: 326 ECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCDH---SCINH 381
Query: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSG 2375
GTF C C G C D NEC G C+ CVN +GSY C+C+ G++ +
Sbjct: 382 PGTFACACNRGYTLY-GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNK 439
Query: 2376 TECLD 2380
+C++
Sbjct: 440 KDCVE 444
Score = 169 bits (429), Expect = 3e-41
Identities = 133/476 (27%), Positives = 194/476 (40%), Gaps = 83/476 (17%)
Query: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNG---DC 549
Q +D C H LC N T +SY+C C GY+ + C D+DEC N G DC
Sbjct: 51 QGLDDC-HADALCQN-----TPTSYKCSCKPGYQGEGR-QCEDIDEC-GNELNGGCVHDC 102
Query: 550 VNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELT 609
+N PG+Y C C GF C+D+DEC++N C++ CVN GS++C C GF L+
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLS 161
Query: 610 TDGKNCVDHDE----CTTTNMCLNGMCINED-GSFKCICKPGFVLAPNGRYCTDVDECQT 664
+ C+ E C + + +C GS C C+PGF LA N R C + C
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNH 219
Query: 665 PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTH----------------------- 701
C ++ C C P + DGR C++
Sbjct: 220 GNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKR 279
Query: 702 --MRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF-----GEPCQP---CPAKNSA- 750
+ TC + G C R T C C GF G+ C+ C +N
Sbjct: 280 RLLMETC--AVNNGGCDRTCKDTSTGVHCSCP---VGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 751 ---------EFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCNSG 798
F C G + D + D++EC+LD + C N G++ C CN G
Sbjct: 335 DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRT--CDHSCINHPGTFACACNRG 392
Query: 799 YEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDIN---E 855
Y +C D +EC +N C +C NT GSY C C PGY + C ++
Sbjct: 393 YTLYGF-THCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLP 450
Query: 856 CESNPCVNGACRNNLGSFNC--ECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEV 909
+P V+ C + G C C G LSS + +++ + + + +C +
Sbjct: 451 TSVSPRVSLHCGKSGGGDGCFLRCHSGIHLSSD----VTTIRTSVTFKLNEGKCSL 502
Score = 169 bits (428), Expect = 4e-41
Identities = 134/466 (28%), Positives = 189/466 (40%), Gaps = 88/466 (18%)
Query: 940 ACPRGLARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 998
A P G R G EDV+EC C + C N+ S+ C C G G GR C DI
Sbjct: 31 AVPPGRGRAAGPQ-EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGEGRQCEDI 87
Query: 999 RMEQCYLKWDEDECIHP---VPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRG 1055
++C + + C+H +PG +R C C G + C
Sbjct: 88 --DECGNELNGG-CVHDCLNIPGNYR---CTCFDGFMLAHDGHNC--------------- 126
Query: 1056 AGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 1115
D++EC G C + C N +GS++C C GF L + C
Sbjct: 127 ----------------LDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTCIH 169
Query: 1116 IDECRIS---PDLCGSGICVNTP-GSFECECFEGYESGFMMMKNCMD-IDECERNPLLCR 1170
E +S D S IC P GS CEC G+E + KN D I C C+
Sbjct: 170 RSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE----LAKNQRDCILTCNHGNGGCQ 225
Query: 1171 GGTCVNTEGSFQCDCPLGHELSPSREDCVD----------------------------IN 1202
+C +T +C C +++ C++ +
Sbjct: 226 H-SCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLME 284
Query: 1203 ECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEG 1262
C++++ C + C + CSC G+ D + C DIDEC NGGCD C N G
Sbjct: 285 TCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 1263 SYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT 1322
S++C C +G+ L+ D +SC D+DEC + CD C N PG + C C G+
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCD-HSCINHPGTFACACNRGY-TLYGFTH 400
Query: 1323 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDV 1368
C D NEC +N+ C C NT GS+ C C GY + C +V
Sbjct: 401 CGDTNECSINNGGCQ-QVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 169 bits (427), Expect = 5e-41
Identities = 127/465 (27%), Positives = 194/465 (41%), Gaps = 103/465 (22%)
Query: 575 DIDECIQNGVLCK-NGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCI 633
D+DEC Q C + C NT S++C C G++ +G+ C D DEC LNG C+
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNE---LNGGCV 99
Query: 634 NE----DGSFKCICKPGFVLAPNGRYCTDVDEC-QTPGICMNGHCINSEGSFRCDCPPGL 688
++ G+++C C GF+LA +G C DVDEC + G C + C+N GS+ C C G
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHT-CVNVMGSYECCCKEGF 158
Query: 689 AVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKN 748
+ + C+ ++ C N D+G C+ P +
Sbjct: 159 FLSDNQHTCIHR-----------------------SEEGLSCMNKDHGCSHICKEAPRGS 195
Query: 749 SAEFHGLCSSGVGITVDGRD-INECALDPDICANGICENLRGSYRCNCNSGYEPDASGRN 807
A C G + + RD I C C + C++ C+C+ Y+ GR+
Sbjct: 196 VA---CECRPGFELAKNQRDCILTCNHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRS 251
Query: 808 CID----------------------------IDECLVNRLLCDNGLCRNTPGSYSCTCPP 839
C++ ++ C VN CD C++T C+CP
Sbjct: 252 CLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPV 310
Query: 840 GYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGSKLSSTGLICID----SL 894
G+ + + +TC+DI+EC++ N + C+N +GSF+C C G KL + C D SL
Sbjct: 311 GFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL 370
Query: 895 KGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE 954
TC D C +N G AC RG C
Sbjct: 371 DRTC-----DHSC-INHPGT----------------------FACACNRGYTLYGFTHCG 402
Query: 955 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 999
D NEC + G C CVN+ GS+ C+C G L + C++++
Sbjct: 403 DTNECSINNGGCQQV-CVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 161 bits (408), Expect = 8e-39
Identities = 135/457 (29%), Positives = 188/457 (41%), Gaps = 101/457 (22%)
Query: 1691 EDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
ED+DEC C C NT +Y C C P Y G C D+ + C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDE-----------C 90
Query: 1750 ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
NEL C ++ C P +++ C GF +D+
Sbjct: 91 GNELNGG-------CVHD--------CLNIP----GNYRCTC--FDGFMLAHDGHNCLDV 129
Query: 1810 DECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC----EDIDECSNGDNLCQRNA 1865
DEC E G C + C+N +GS+ C C GF +D C E+ C N D+ C
Sbjct: 130 DECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI- 187
Query: 1866 DCINSP-GSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHG------LCVDLQGSYQCI 1918
C +P GS CEC GF+L+ N + +C+ C+HG C D +C
Sbjct: 188 -CKEAPRGSVACECRPGFELAKN-----QRDCIL---TCNHGNGGCQHSCDDTADGPECS 238
Query: 1919 CHNGFKASQDQTMCMDVDEC-------------------------ERHPCGNG----TCK 1949
CH +K D C++ ++ E NG TCK
Sbjct: 239 CHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCK 298
Query: 1950 NTVGSYNCLCYPGFELT-HNNDCLDIDECSSFFGQVCRNGRCF----NEIGSFKCLCNEG 2004
+T +C C GF L C DIDEC + RNG C N +GSF C C +G
Sbjct: 299 DTSTGVHCSCPVGFTLQLDGKTCKDIDECQT------RNGGCDHFCKNIVGSFDCGCKKG 352
Query: 2005 YELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKS-ENCIDINECDED 2063
++L D K+C D +EC +L +C +C N G+F C C GY + +C D NEC +
Sbjct: 353 FKLLTDEKSCQDVDEC-SLDRTCDH-SCINHPGTFACACNRGYTLYGFTHCGDTNECSIN 410
Query: 2064 PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
C C NT G ++C C PG+ L N + C + +
Sbjct: 411 NGGCQ-QVCVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 157 bits (398), Expect = 1e-37
Identities = 128/453 (28%), Positives = 180/453 (39%), Gaps = 67/453 (14%)
Query: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGIC-SNGQCINT 2190
PG W L + P G G +EDV+EC + C ++ C NT
Sbjct: 9 PGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAG---PQEDVDECAQGLDDCHADALCQNT 65
Query: 2191 DGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT---CTNVIGSFECNCNEGFEPG- 2246
S++C C GY + G +C D DEC GN G C N+ G++ C C +GF
Sbjct: 66 PTSYKCSCKPGYQGE--GRQCEDIDEC--GNELNGGCVHDCLNIPGNYRCTCFDGFMLAH 121
Query: 2247 PMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCE 2306
NC D++EC +N C C+N GSYEC C G+ L ++Q C E EGL C
Sbjct: 122 DGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE--EGL-SCM 178
Query: 2307 SRGMMCKNLI-----GTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSY 2361
++ C ++ G+ C C PG + C+ C G C++ C +
Sbjct: 179 NKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCI--LTCNHGNGGCQHS-CDDTADGP 235
Query: 2362 RCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSR-NLVTKSECCCDGGRGWGH 2420
C C+ ++ + G CL+ + T + R E C G
Sbjct: 236 ECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR 295
Query: 2421 QCE--------LCPLPGTAQY----------------------KKI-------CPHGPGY 2443
C+ CP+ T Q K I C G
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKL 355
Query: 2444 TTDGR---DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPK 2500
TD + D+DEC + C + CIN G+F C C GYT T C D +ECS +
Sbjct: 356 LTDEKSCQDVDECS-LDRTCDHS-CINHPGTFACACNRGYTL-YGFTHCGDTNECSINNG 412
Query: 2501 PCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL 2533
C +C NT GSY+C C GY L + K C ++
Sbjct: 413 GCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 117 bits (294), Expect = 1e-25
Identities = 71/223 (31%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 2559 PPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC 2618
PPG + D +EC C A +CQNTP S+ C C+ G+ G CED+DEC
Sbjct: 33 PPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDEC 90
Query: 2619 DG--NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSY 2676
N C H C NI G YRC C G++ + + C+D +EC N +C N +GSY
Sbjct: 91 GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSY 150
Query: 2677 KCACPSGFSFDQFSSACHDVNE----CSSSKNPCNYGCSNT-EGGYLCGCPPGY-YRVGQ 2730
+C C GF C +E C + + C++ C G C C PG+ Q
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQ 210
Query: 2731 GHCVSGMGFNKG--QYLSLDTEVDEENALSPEACYECKINGYS 2771
C+ G Q+ DT E + P+ Y+ +G S
Sbjct: 211 RDCILTCNHGNGGCQHSCDDTADGPECSCHPQ--YKMHTDGRS 251
Score = 80.5 bits (197), Expect = 2e-14
Identities = 49/133 (36%), Positives = 64/133 (48%), Gaps = 8/133 (6%)
Query: 261 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDID 320
C GF + C+D+DECQ G C C N VGSF+C C G K + C+D+D
Sbjct: 308 CPVGFTLQLDGKTCKDIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVD 366
Query: 321 ECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELP 380
ECS + C+ C N G++ C C RGY T + C D T C + NG C Q
Sbjct: 367 ECS-LDRTCD-HSCINHPGTFACACNRGY-TLYGFTHCGD--TNEC--SINNGGCQQVCV 419
Query: 381 GRMTKMQCCCEPG 393
+ +C C PG
Sbjct: 420 NTVGSYECQCHPG 432
Score = 73.6 bits (179), Expect = 3e-12
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 12/155 (7%)
Query: 244 GRAWGHPCEMCPAQPQPCRRGFIPNIR---TGACQDVDEC-QAIPGICQGGNCINTVGSF 299
G AW + P G +P R G +DVDEC Q + C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 300 ECRCPAGHKQSETTQKCEDIDEC-SIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
+C C G+ Q E Q CEDIDEC + + G C +C N G+Y C C G++ + DG C
Sbjct: 70 KCSCKPGY-QGEGRQ-CEDIDECGNELNGGC-VHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Query: 359 IDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
+D C NG C M +CCC+ G
Sbjct: 127 LD--VDECLEN--NGGCQHTCVNVMGSYECCCKEG 157
Score = 61.2 bits (147), Expect = 1e-08
Identities = 39/124 (31%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 274 CQDVDEC-QAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
C+D+DEC + G C +C+N G++ C C G + C D+DEC G C+
Sbjct: 84 CEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-H 141
Query: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQ-RTGMCFSGLVNG--RCAQELPGRMTKMQCC 389
C N +GSY C C G+ S + CI + G+ +G +E P + C
Sbjct: 142 TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAP--RGSVACE 199
Query: 390 CEPG 393
C PG
Sbjct: 200 CRPG 203
Score = 53.1 bits (126), Expect = 4e-06
Identities = 67/260 (25%), Positives = 99/260 (38%), Gaps = 57/260 (21%)
Query: 130 CTCSSGQISSTCGSKSIQ-QCSVRC-----MNGGTCAD-DHCQCQKGYIGTYCGQPVCEN 182
C ++G TC S CS ++G TC D D CQ + G C++
Sbjct: 286 CAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGG---------CDH 336
Query: 183 GCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCAT 242
C+N +G C C GF + + CQ + +
Sbjct: 337 FCKN---IVGSFDCGCKKGFK--------------LLTDEKSCQD----------VDECS 369
Query: 243 IGRAWGHPCEMCPAQ-PQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFEC 301
+ R H C P C RG+ T C D +EC G CQ C+NTVGS+EC
Sbjct: 370 LDRTCDHSCINHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQQV-CVNTVGSYEC 427
Query: 302 RCPAGHKQSETTQKCEDID---ECSIIPGICETGECSNTVGSYFCV--CPRGYVTSTDGS 356
+C G+K + C ++ S+ P + + C + G C C G S+D +
Sbjct: 428 QCHPGYKLHWNKKDCVEVKGLLPTSVSPRV--SLHCGKSGGGDGCFLRCHSGIHLSSDVT 485
Query: 357 RCIDQRTGMCFSGLVNGRCA 376
RT + F L G+C+
Sbjct: 486 TI---RTSVTFK-LNEGKCS 501
Score = 42.7 bits (99), Expect = 0.005
Identities = 54/194 (27%), Positives = 68/194 (35%), Gaps = 31/194 (15%)
Query: 1810 DECKEIPGICANGVCINQIGSFRCE-CPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
D +E +C NG N+ G CE CP N L + S LCQ
Sbjct: 648 DGARERCILCPNGTFQNEEGQMTCEPCPR--PGNSGALKTPEAWNMSECGGLCQ------ 699
Query: 1869 NSPGSYRCECAAGFKLSPNGAC---VDRNECLEIPNVCSHGLCVDLQG--SYQCICHNGF 1923
PG Y + A +L G R C C GL QG S+Q C
Sbjct: 700 --PGEYSADGFAPCQLCALGTFQPEAGRTSCFP----CGGGLATKHQGATSFQD-CETRV 752
Query: 1924 KASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQ 1983
+ S C R C GT + G NC+ PG N D D ++
Sbjct: 753 QCSPGHFYNTTTHRCIR--CPVGTYQPEFGKNNCVSCPG------NTTTDFDGSTNI--T 802
Query: 1984 VCRNGRCFNEIGSF 1997
C+N RC E+G F
Sbjct: 803 QCKNRRCGGELGDF 816
Score = 42.0 bits (97), Expect = 0.009
Identities = 49/213 (23%), Positives = 62/213 (29%), Gaps = 69/213 (32%)
Query: 249 HPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGH 307
H C P + C GF+ C DVDEC G CQ C+N +GS+EC C G
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF 158
Query: 308 KQSETTQKCEDIDE-------------------------CSIIPGI------------CE 330
S+ C E C PG C
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCN 218
Query: 331 TGE------CSNTVGSYFCVCPRGYVTSTDGSRCIDQ----------------------- 361
G C +T C C Y TDG C+++
Sbjct: 219 HGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVK 278
Query: 362 -RTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
R M + NG C + T + C C G
Sbjct: 279 RRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVG 311
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.487
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 152,529,062
Number of Sequences: 37866
Number of extensions: 9176369
Number of successful extensions: 90025
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 372
Number of HSP's successfully gapped in prelim test: 493
Number of HSP's that attempted gapping in prelim test: 31109
Number of HSP's gapped (non-prelim): 17879
length of query: 2912
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2792
effective length of database: 13,703,598
effective search space: 38260445616
effective search space used: 38260445616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.