Search of human proteins with 62953113

Search of human proteins with 62953113

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62953113 caspase-1 dominant-negative inhibitor pseudo-ICE
isoform 1 [Homo sapiens]
         (197 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62953113 caspase-1 dominant-negative inhibitor pseudo-ICE iso...   401   e-112
gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]            229   1e-60
gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]          216   8e-57
gi|16751833 caspase-1 dominant-negative inhibitor pseudo-ICE iso...   180   8e-46
gi|55925612 caspase recruitment domain family, member 17 [Homo s...   146   1e-35
gi|10954343 ICEBERG caspase-1 inhibitor [Homo sapiens]                102   3e-22
gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]           61   5e-10
gi|15431332 caspase 1 isoform delta [Homo sapiens]                     61   5e-10
gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]            45   3e-05
gi|7662404 caspase recruitment domain family, member 8 [Homo sap...    41   6e-04
gi|15431334 caspase 1 isoform epsilon [Homo sapiens]                   39   0.002
gi|40788015 caspase recruitment domain protein 12 [Homo sapiens]       38   0.005
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap...    37   0.014
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa...    35   0.032
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap...    35   0.032
gi|209870071 caspase 5 isoform b precursor [Homo sapiens]              35   0.032
gi|209870079 caspase 5 isoform f precursor [Homo sapiens]              34   0.092
gi|209870069 caspase 5 isoform a precursor [Homo sapiens]              34   0.092
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]             32   0.27 
gi|11545912 nucleotide-binding oligomerization domain containing...    32   0.46 
gi|16554564 caspase recruitment domain family, member 6 [Homo sa...    31   0.78 
gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]       30   1.3  
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               29   3.0  
gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens]    28   5.0  
gi|145309298 coiled-coil domain containing 16 [Homo sapiens]           28   5.0  
gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]            28   6.6  
gi|239746604 PREDICTED: similar to Keratin-associated protein 10...    28   6.6  
gi|118442825 methyltransferase like 6 [Homo sapiens]                   28   6.6  
gi|21704263 MAX protein isoform b [Homo sapiens]                       27   8.6  
gi|21704261 MAX protein isoform a [Homo sapiens]                       27   8.6  

>gi|62953113 caspase-1 dominant-negative inhibitor pseudo-ICE
           isoform 1 [Homo sapiens]
          Length = 197

 Score =  401 bits (1030), Expect = e-112
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
           MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS
Sbjct: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60

Query: 61  VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
           VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA
Sbjct: 61  VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120

Query: 121 QRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYP 180
           QRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYP
Sbjct: 121 QRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYP 180

Query: 181 RIPGLGKELQTGTHKLS 197
           RIPGLGKELQTGTHKLS
Sbjct: 181 RIPGLGKELQTGTHKLS 197


>gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]
          Length = 383

 Score =  229 bits (583), Expect = 1e-60
 Identities = 116/127 (91%), Positives = 119/127 (93%)

Query: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
           MADKVLKEKRKLFI SMGEGTINGLLDELLQTRVLN+EEMEKVKRENATVMDKTRALIDS
Sbjct: 1   MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS 60

Query: 61  VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
           VIPKGAQACQICITYICEEDSYLA TLGLSAA QAVQDNPAMPT S  EG +KLC LE+A
Sbjct: 61  VIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEA 120

Query: 121 QRIWKQK 127
           QRIWKQK
Sbjct: 121 QRIWKQK 127


>gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]
          Length = 404

 Score =  216 bits (551), Expect = 8e-57
 Identities = 116/148 (78%), Positives = 119/148 (80%), Gaps = 21/148 (14%)

Query: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
           MADKVLKEKRKLFI SMGEGTINGLLDELLQTRVLN+EEMEKVKRENATVMDKTRALIDS
Sbjct: 1   MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS 60

Query: 61  VIPKGAQACQICITYICEEDSYLAETLGLSA---------------------ALQAVQDN 99
           VIPKGAQACQICITYICEEDSYLA TLGLSA                     A QAVQDN
Sbjct: 61  VIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN 120

Query: 100 PAMPTCSSPEGRIKLCFLEDAQRIWKQK 127
           PAMPT S  EG +KLC LE+AQRIWKQK
Sbjct: 121 PAMPTSSGSEGNVKLCSLEEAQRIWKQK 148


>gi|16751833 caspase-1 dominant-negative inhibitor pseudo-ICE
          isoform 2 [Homo sapiens]
          Length = 97

 Score =  180 bits (456), Expect = 8e-46
 Identities = 91/91 (100%), Positives = 91/91 (100%)

Query: 1  MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
          MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS
Sbjct: 1  MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60

Query: 61 VIPKGAQACQICITYICEEDSYLAETLGLSA 91
          VIPKGAQACQICITYICEEDSYLAETLGLSA
Sbjct: 61 VIPKGAQACQICITYICEEDSYLAETLGLSA 91


>gi|55925612 caspase recruitment domain family, member 17 [Homo
          sapiens]
          Length = 110

 Score =  146 bits (369), Expect = 1e-35
 Identities = 76/91 (83%), Positives = 82/91 (90%)

Query: 1  MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
          MADKVLKEKRK FI S+GEGTINGLL ELL+TRVL+QEE+E VK ENATVMDK RAL+DS
Sbjct: 1  MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS 60

Query: 61 VIPKGAQACQICITYICEEDSYLAETLGLSA 91
          VI KGA ACQICITYICEEDS+LA TLGLSA
Sbjct: 61 VIRKGAPACQICITYICEEDSHLAGTLGLSA 91


>gi|10954343 ICEBERG caspase-1 inhibitor [Homo sapiens]
          Length = 90

 Score =  102 bits (253), Expect = 3e-22
 Identities = 50/89 (56%), Positives = 67/89 (75%)

Query: 1  MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
          MAD++L++KR++FIHS+G GTIN LLD LL+  V++QE+M KV+ EN TVMDK R LID 
Sbjct: 1  MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL 60

Query: 61 VIPKGAQACQICITYICEEDSYLAETLGL 89
          V  KG ++C   I ++CEED  LA  +GL
Sbjct: 61 VTGKGPKSCCKFIKHLCEEDPQLASKMGL 89


>gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]
          Length = 311

 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 28/39 (71%), Positives = 31/39 (79%)

Query: 89  LSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQK 127
           +  A QAVQDNPAMPT S  EG +KLC LE+AQRIWKQK
Sbjct: 17  MGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQK 55



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 18/19 (94%), Positives = 18/19 (94%)

Query: 1  MADKVLKEKRKLFIHSMGE 19
          MADKVLKEKRKLFI SMGE
Sbjct: 1  MADKVLKEKRKLFIRSMGE 19


>gi|15431332 caspase 1 isoform delta [Homo sapiens]
          Length = 263

 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 28/39 (71%), Positives = 31/39 (79%)

Query: 89  LSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQK 127
           +  A QAVQDNPAMPT S  EG +KLC LE+AQRIWKQK
Sbjct: 17  MGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQK 55



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 18/19 (94%), Positives = 18/19 (94%)

Query: 1  MADKVLKEKRKLFIHSMGE 19
          MADKVLKEKRKLFI SMGE
Sbjct: 1  MADKVLKEKRKLFIRSMGE 19


>gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]
          Length = 377

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 6/132 (4%)

Query: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
           MA+   ++K    + S+G+  + G+LD L++  VLN +E EK K  +A   DK R + DS
Sbjct: 1   MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADS 60

Query: 61  VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
           +  K   A Q+ +      D           A   ++  P  P        +KLC  E+ 
Sbjct: 61  MQEKQRMAGQMLLQTFFNIDQISPN----KKAHPNMEAGP--PESGESTDALKLCPHEEF 114

Query: 121 QRIWKQKLQRCH 132
            R+ K++ +  +
Sbjct: 115 LRLCKERAEEIY 126


>gi|7662404 caspase recruitment domain family, member 8 [Homo
           sapiens]
          Length = 431

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 20  GTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEE 79
           G + G+LD+L    VL + E E V++E  T   K  AL+  V  KG  A  +    I E 
Sbjct: 360 GDLKGVLDDLQDNEVLTENEKELVEQEK-TRQSKNEALLSMVEKKGDLALDVLFRSISER 418

Query: 80  DSYLAETL 87
           D YL   L
Sbjct: 419 DPYLVSYL 426


>gi|15431334 caspase 1 isoform epsilon [Homo sapiens]
          Length = 88

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 18/23 (78%), Positives = 20/23 (86%)

Query: 1  MADKVLKEKRKLFIHSMGEGTIN 23
          MADKVLKEKRKLFI SMGE  ++
Sbjct: 1  MADKVLKEKRKLFIRSMGEDNVS 23


>gi|40788015 caspase recruitment domain protein 12 [Homo sapiens]
          Length = 1024

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 6  LKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKG 65
          +K+  +  I  MG   I  + D+L    VLN+EE+  +  E     D  R +I  ++ KG
Sbjct: 4  IKDNSRALIQRMGMTVIKQITDDLFVWNVLNREEVNIICCEKVE-QDAARGIIHMILKKG 62

Query: 66 AQACQICITYICE 78
          +++C + +  + E
Sbjct: 63 SESCNLFLKSLKE 75


>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
           sapiens]
          Length = 618

 Score = 36.6 bits (83), Expect = 0.014
 Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 24/140 (17%)

Query: 25  LLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLA 84
           +LD LL+  V+N++E + +K++    + + R LID+++ KG  A  I    + E DS L 
Sbjct: 478 ILDNLLKANVINKQEHDIIKQKTQIPL-QARELIDTILVKGNAAANIFKNCLKEIDSTLY 536

Query: 85  ET-----------------LGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQK 127
           +                  L L   L+ +Q+      C   E  + + F+     +  Q+
Sbjct: 537 KNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKE--VSVVFIPCGHLVVCQE 594

Query: 128 ----LQRCHVQNTIIKWSER 143
               L++C +   IIK + R
Sbjct: 595 CAPSLRKCPICRGIIKGTVR 614


>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 35.4 bits (80), Expect = 0.032
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 4/83 (4%)

Query: 5   VLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPK 64
           + K +  LF H      +  +LD LL   ++N++E + +K++  T + + R LID+++ K
Sbjct: 447 IRKNRMALFQHLT---CVIPILDSLLTAGIINEQEHDVIKQKTQTSL-QARELIDTILVK 502

Query: 65  GAQACQICITYICEEDSYLAETL 87
           G  A  +    + E ++ L E L
Sbjct: 503 GNIAATVFRNSLQEAEAVLYEHL 525


>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 35.4 bits (80), Expect = 0.032
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 4/83 (4%)

Query: 5   VLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPK 64
           + K +  LF H      +  +LD LL   ++N++E + +K++  T + + R LID+++ K
Sbjct: 447 IRKNRMALFQHLT---CVIPILDSLLTAGIINEQEHDVIKQKTQTSL-QARELIDTILVK 502

Query: 65  GAQACQICITYICEEDSYLAETL 87
           G  A  +    + E ++ L E L
Sbjct: 503 GNIAATVFRNSLQEAEAVLYEHL 525


>gi|209870071 caspase 5 isoform b precursor [Homo sapiens]
          Length = 376

 Score = 35.4 bits (80), Expect = 0.032
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 7/126 (5%)

Query: 1   MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS 60
           MA+   K+K    +  +G+  ++G+ + L +  VL  +E EK K  +  + DK   L+DS
Sbjct: 1   MAEDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDS 60

Query: 61  VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
            + K   A Q+    +   D  +     L      +Q     P  +     +KLC  E+ 
Sbjct: 61  -LRKNRVAHQMFTQTLLNMDQKITSVKPL------LQIEAGPPESAESTNILKLCPREEF 113

Query: 121 QRIWKQ 126
            R+ K+
Sbjct: 114 LRLCKK 119


>gi|209870079 caspase 5 isoform f precursor [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.092
 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 7   KEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGA 66
           K+K    +  +G+  ++G+ + L +  VL  +E EK K  +  + DK   L+DS + K  
Sbjct: 78  KKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDS-LRKNR 136

Query: 67  QACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQ 126
            A Q+    +   D  +     L      +Q     P  +     +KLC  E+  R+ K+
Sbjct: 137 VAHQMFTQTLLNMDQKITSVKPL------LQIEAGPPESAESTNILKLCPREEFLRLCKK 190


>gi|209870069 caspase 5 isoform a precursor [Homo sapiens]
          Length = 434

 Score = 33.9 bits (76), Expect = 0.092
 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 7   KEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGA 66
           K+K    +  +G+  ++G+ + L +  VL  +E EK K  +  + DK   L+DS + K  
Sbjct: 65  KKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDS-LRKNR 123

Query: 67  QACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQ 126
            A Q+    +   D  +     L      +Q     P  +     +KLC  E+  R+ K+
Sbjct: 124 VAHQMFTQTLLNMDQKITSVKPL------LQIEAGPPESAESTNILKLCPREEFLRLCKK 177


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 32.3 bits (72), Expect = 0.27
 Identities = 15/36 (41%), Positives = 23/36 (63%)

Query: 13  FIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENA 48
           F  S+ E  +N L++ LL   VL++EE EK+  EN+
Sbjct: 871 FKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENS 906



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 23   NGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSV 61
            N   D +L+   +  +  EKVK E   V D+ +A++DS+
Sbjct: 3235 NDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSI 3273


>gi|11545912 nucleotide-binding oligomerization domain containing 2
           [Homo sapiens]
          Length = 1040

 Score = 31.6 bits (70), Expect = 0.46
 Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 19/149 (12%)

Query: 2   ADKVLKEKRKLFIHSMGEGTING---LLDELLQTRVLNQEEMEKVKRENATVMDKTRALI 58
           + +  + +R   +  +  G++ G   +LD LL   VL+ E+ E        +    R L+
Sbjct: 30  SQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLL 89

Query: 59  DSVIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLE 118
           D+V  KG  ACQ              + +  +   QA   +P +  C  P        L+
Sbjct: 90  DTVWNKGTWACQ--------------KLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQ 135

Query: 119 DAQRIWKQKLQRCHVQNTI-IKWSERYTS 146
             +    ++L   HV+N + + W   + S
Sbjct: 136 SHRPAIVRRL-HSHVENMLDLAWERGFVS 163


>gi|16554564 caspase recruitment domain family, member 6 [Homo
          sapiens]
          Length = 1037

 Score = 30.8 bits (68), Expect = 0.78
 Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 4/68 (5%)

Query: 4  KVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENAT-VMDKTRALIDSVI 62
          ++++ +RK  +  +     + +LD L   R++++EE E +  EN T ++ K+R L+  V 
Sbjct: 9  EIIERERKKLLEILQHDP-DSILDTLTSRRLISEEEYETL--ENVTDLLKKSRKLLILVQ 65

Query: 63 PKGAQACQ 70
           KG   CQ
Sbjct: 66 KKGEATCQ 73


>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
          Length = 557

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 12/28 (42%), Positives = 19/28 (67%), Gaps = 2/28 (7%)

Query: 134 QNTIIKWSERYTSGSFEMQWL--FLRTN 159
           QN ++KW   Y + +F++QWL  FL+ N
Sbjct: 242 QNYVLKWDYTYANMTFQVQWLHAFLKRN 269


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 65  GAQACQICITYICEEDSYLAETLG----LSAALQAVQDNPAMPTCSSPE 109
           G+  C++C+T    E SYLA T G     + A +A ++    P   +PE
Sbjct: 52  GSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPE 100


>gi|34303932 transmembrane and coiled-coil domains 5A [Homo
          sapiens]
          Length = 288

 Score = 28.1 bits (61), Expect = 5.0
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 2/39 (5%)

Query: 19 EGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRAL 57
          E  I  L  E++QTR L ++E  + ++EN T M++ RAL
Sbjct: 42 EDKIQRLESEIIQTRGLVEDE--EWEKENRTTMERERAL 78


>gi|145309298 coiled-coil domain containing 16 [Homo sapiens]
          Length = 372

 Score = 28.1 bits (61), Expect = 5.0
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 33 RVLNQEEMEKVKRENATVMDKTRALIDSVIPK----GAQACQICITYICEEDSYLAETLG 88
          RV+NQEE+ ++ +E    +  +R  I+S   K    G  +C +C T +  E  +    LG
Sbjct: 14 RVINQEELRRLMKEKQR-LSTSRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLG 72


>gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 312

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 15/47 (31%), Positives = 22/47 (46%)

Query: 74  TYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
           ++ C  +S LA+  G   AL      PA P C+ P   + L F + A
Sbjct: 88  SFYCPYNSRLAKNCGAQVALPLSLTLPASPCCAWPCNAVSLGFWDAA 134


>gi|239746604 PREDICTED: similar to Keratin-associated protein 10-8
           [Homo sapiens]
          Length = 312

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 15/47 (31%), Positives = 22/47 (46%)

Query: 74  TYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA 120
           ++ C  +S LA+  G   AL      PA P C+ P   + L F + A
Sbjct: 88  SFYCPYNSRLAKNCGAQVALPLSLTLPASPCCAWPCNAVSLGFWDAA 134


>gi|118442825 methyltransferase like 6 [Homo sapiens]
          Length = 284

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 12/23 (52%), Positives = 15/23 (65%)

Query: 30 LQTRVLNQEEMEKVKRENATVMD 52
          LQ R+L  EE EK+KR+   V D
Sbjct: 9  LQARILTSEEEEKLKRDQTLVSD 31


>gi|21704263 MAX protein isoform b [Homo sapiens]
          Length = 151

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 36  NQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGLS-AALQ 94
           +Q++++ +KR+NA +  + RAL      K   + Q+   Y   ++S      G + +A  
Sbjct: 72  HQQDIDDLKRQNALLEQQVRAL-----EKARSSAQLQTNYPSSDNSLYTNAKGSTISAFD 126

Query: 95  AVQDNPAMPTCSSPEGRIKL 114
              D+ +      P+ R KL
Sbjct: 127 GGSDSSSESEPEEPQSRKKL 146


>gi|21704261 MAX protein isoform a [Homo sapiens]
          Length = 160

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 36  NQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGLS-AALQ 94
           +Q++++ +KR+NA +  + RAL      K   + Q+   Y   ++S      G + +A  
Sbjct: 81  HQQDIDDLKRQNALLEQQVRAL-----EKARSSAQLQTNYPSSDNSLYTNAKGSTISAFD 135

Query: 95  AVQDNPAMPTCSSPEGRIKL 114
              D+ +      P+ R KL
Sbjct: 136 GGSDSSSESEPEEPQSRKKL 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,612,096
Number of Sequences: 37866
Number of extensions: 319456
Number of successful extensions: 931
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 903
Number of HSP's gapped (non-prelim): 34
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.