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Search of human proteins with 62912487
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 835 0.0
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 811 0.0
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 811 0.0
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 478 e-135
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 478 e-135
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 478 e-135
gi|15718767 TRAAK [Homo sapiens] 313 2e-85
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 194 1e-49
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 194 1e-49
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 177 2e-44
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 177 2e-44
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 162 5e-40
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 150 2e-36
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 145 7e-35
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 135 5e-32
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 134 2e-31
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 132 8e-31
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 130 3e-30
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 125 6e-29
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 110 2e-24
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 110 2e-24
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 110 2e-24
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 110 2e-24
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 108 7e-24
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 102 9e-22
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 67 3e-11
gi|22024390 potassium voltage-gated channel, subfamily H, member... 44 2e-04
gi|27886648 potassium voltage-gated channel, subfamily H, member... 44 2e-04
gi|27886646 potassium voltage-gated channel, subfamily H, member... 44 2e-04
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 41 0.002
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 835 bits (2158), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST 60
MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
Sbjct: 1 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST 60
Query: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
Sbjct: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
Query: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
Sbjct: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
Query: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII 240
FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
Sbjct: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII 240
Query: 241 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL 300
FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
Sbjct: 241 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL 300
Query: 301 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK 360
SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
Sbjct: 301 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK 360
Query: 361 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN 420
LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
Sbjct: 361 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN 420
Query: 421 IK 422
IK
Sbjct: 421 IK 422
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 811 bits (2095), Expect = 0.0
Identities = 410/411 (99%), Positives = 411/411 (100%)
Query: 12 LAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII 71
+AAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII
Sbjct: 1 MAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII 60
Query: 72 GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT 131
GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT
Sbjct: 61 GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT 120
Query: 132 SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ 191
SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ
Sbjct: 121 SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ 180
Query: 192 LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD 251
LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD
Sbjct: 181 LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD 240
Query: 252 AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS 311
AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS
Sbjct: 241 AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS 300
Query: 312 KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ 371
KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ
Sbjct: 301 KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ 360
Query: 372 ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK 422
ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
Sbjct: 361 ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK 411
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 811 bits (2094), Expect = 0.0
Identities = 410/411 (99%), Positives = 411/411 (100%)
Query: 12 LAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII 71
+AAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII
Sbjct: 16 VAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII 75
Query: 72 GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT 131
GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT
Sbjct: 76 GATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNT 135
Query: 132 SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ 191
SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ
Sbjct: 136 SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ 195
Query: 192 LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD 251
LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD
Sbjct: 196 LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD 255
Query: 252 AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS 311
AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS
Sbjct: 256 AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS 315
Query: 312 KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ 371
KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ
Sbjct: 316 KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ 375
Query: 372 ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK 422
ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
Sbjct: 376 ELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK 426
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 478 bits (1231), Expect = e-135
Identities = 247/394 (62%), Positives = 305/394 (77%), Gaps = 23/394 (5%)
Query: 9 DFYL------AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---IN 51
DF+L AA + PKSA A PRLS S++ TV+A R+E +
Sbjct: 7 DFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQT 65
Query: 52 VMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELD 111
VMKWKTV IF+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+
Sbjct: 66 VMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELE 125
Query: 112 ELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCI 171
LIQ + A NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI
Sbjct: 126 TLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCI 185
Query: 172 IYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCV 231
+YA+ GIPLFGFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC+
Sbjct: 186 LYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCI 245
Query: 232 LFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWIL 290
+FV +PA+IFK+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWIL
Sbjct: 246 VFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWIL 305
Query: 291 VGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDK 350
VGLAYFAAVLSMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK
Sbjct: 306 VGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDK 365
Query: 351 FQRATSI----KRKLSAELAGNHNQELTPCRRTL 380
QRA +I +R+L + + L+P +R++
Sbjct: 366 LQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSV 399
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 478 bits (1229), Expect = e-135
Identities = 244/384 (63%), Positives = 301/384 (78%), Gaps = 17/384 (4%)
Query: 13 AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---INVMKWKTVSTI 61
AA + PKSA A PRLS S++ TV+A R+E + VMKWKTV I
Sbjct: 22 AAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQTVMKWKTVVAI 80
Query: 62 FLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAI 121
F+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+ LIQ + A
Sbjct: 81 FVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDAD 140
Query: 122 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 181
NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI+YA+ GIPLF
Sbjct: 141 NAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLF 200
Query: 182 GFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIF 241
GFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC++FV +PA+IF
Sbjct: 201 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIF 260
Query: 242 KHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVL 300
K+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWILVGLAYFAAVL
Sbjct: 261 KYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 320
Query: 301 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSI--- 357
SMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK QRA +I
Sbjct: 321 SMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSM 380
Query: 358 -KRKLSAELAGNHNQELTPCRRTL 380
+R+L + + L+P +R++
Sbjct: 381 ERRRLGLDQRAHSLDMLSPEKRSV 404
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 478 bits (1229), Expect = e-135
Identities = 244/384 (63%), Positives = 301/384 (78%), Gaps = 17/384 (4%)
Query: 13 AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---INVMKWKTVSTI 61
AA + PKSA A PRLS S++ TV+A R+E + VMKWKTV I
Sbjct: 22 AAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQTVMKWKTVVAI 80
Query: 62 FLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAI 121
F+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+ LIQ + A
Sbjct: 81 FVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDAD 140
Query: 122 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 181
NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI+YA+ GIPLF
Sbjct: 141 NAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLF 200
Query: 182 GFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIF 241
GFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC++FV +PA+IF
Sbjct: 201 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIF 260
Query: 242 KHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVL 300
K+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWILVGLAYFAAVL
Sbjct: 261 KYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 320
Query: 301 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSI--- 357
SMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK QRA +I
Sbjct: 321 SMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSM 380
Query: 358 -KRKLSAELAGNHNQELTPCRRTL 380
+R+L + + L+P +R++
Sbjct: 381 ERRRLGLDQRAHSLDMLSPEKRSV 404
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 313 bits (801), Expect = 2e-85
Identities = 145/284 (51%), Positives = 206/284 (72%), Gaps = 2/284 (0%)
Query: 53 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDE 112
M+ T+ + +V+LYL+ GA VF+ALEQPHE + + ++ F+ H CV+ EL
Sbjct: 1 MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGL 60
Query: 113 LIQQIVAAINAGIIPLGNTSNQISH--WDLGSSFFFAGTVITTIGFGNISPRTEGGKIFC 170
LI+++ A+ G P N+++ SH WDLGS+FFF+GT+ITTIG+GN++ RT+ G++FC
Sbjct: 61 LIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFC 120
Query: 171 IIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGC 230
I YAL+GIPLFG LLAGVGD+LG+ GI +E F+KW+V +R++S ++F+L GC
Sbjct: 121 IFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGC 180
Query: 231 VLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWIL 290
+LFV P +F ++E WS L+AIYFV++TLTT+GFGDYVAG + Y+P+VWFWIL
Sbjct: 181 LLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWIL 240
Query: 291 VGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTA 334
+GLAYFA+VL+ IG+WLRV+S++T+ E+G A AA WT VTA
Sbjct: 241 LGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTA 284
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 194 bits (493), Expect = 1e-49
Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)
Query: 58 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 296
++F H+EGWS + YF ITL+TIGFGDYV G + Y+ Y+ + WIL+GLA+
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
Query: 297 AAVLSM 302
A +L +
Sbjct: 248 ALILPL 253
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 194 bits (493), Expect = 1e-49
Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)
Query: 58 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 296
++F H+EGWS + YF ITL+TIGFGDYV G + Y+ Y+ + WIL+GLA+
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
Query: 297 AAVLSM 302
A +L +
Sbjct: 248 ALILPL 253
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 177 bits (448), Expect = 2e-44
Identities = 88/214 (41%), Positives = 135/214 (63%), Gaps = 6/214 (2%)
Query: 58 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG 271
++F H+EGWS + YF ITL+TIGFGDYV G
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 177 bits (448), Expect = 2e-44
Identities = 88/214 (41%), Positives = 135/214 (63%), Gaps = 6/214 (2%)
Query: 58 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG 271
++F H+EGWS + YF ITL+TIGFGDYV G
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 162 bits (410), Expect = 5e-40
Identities = 83/243 (34%), Positives = 138/243 (56%), Gaps = 11/243 (4%)
Query: 65 VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAG 124
++ YL IGA +F+ LE+PH + QK + + C+ LD++++ + A G
Sbjct: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
Query: 125 IIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFL 184
+ GN + ++W+ ++ FA TVITTIG+GN++P+T G++FC+ Y L G+PL
Sbjct: 72 VAITGNQT--FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
Query: 185 LAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHI 244
++ LG FG ++ K VS K +I T+IFI++G ++ + +P +F
Sbjct: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
Query: 245 EGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAYFAAVLSMI 303
EGW+ ++ +Y+ IT++TIGFGD+VAG Y Y+ V WI +GLA+ LS+
Sbjct: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
Query: 304 GDW 306
+W
Sbjct: 242 VNW 244
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 150 bits (380), Expect = 2e-36
Identities = 87/244 (35%), Positives = 135/244 (55%), Gaps = 6/244 (2%)
Query: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
+ L + YL +G VF LE + K + +C++ LD LI+ +V A
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
G L NT++ + W+L SFFF+ + ITTIG+GN+SP T ++FCI +AL+GIPL
Sbjct: 85 YKNGASLLSNTTS-MGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPL 143
Query: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII 240
+L ++LG + +G+ K R ++ +L G +LF+ LP ++
Sbjct: 144 NLVVL----NRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLL 199
Query: 241 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYFAAV 299
F H+EGWS + YF ITL+T+GFGDYV G + + Y +YK +V WIL G+A+ A +
Sbjct: 200 FSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALI 259
Query: 300 LSMI 303
+ +I
Sbjct: 260 IKLI 263
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 145 bits (366), Expect = 7e-35
Identities = 84/245 (34%), Positives = 141/245 (57%), Gaps = 11/245 (4%)
Query: 62 FLVV--VLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVA 119
FLV+ +LYL+ GA VF ++E P+E R + K+ F+ +H C++ +L++ + +++
Sbjct: 25 FLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLE 84
Query: 120 AINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIP 179
A N G+ L N S +WD S+ FFA TV++T G+G+ P ++GGK FCIIY+++GIP
Sbjct: 85 ASNYGVSVLSNASGN-WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
Query: 180 LFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTII--FILFGCVLFVALP 237
L V ++ + V I+W S+ + I+ ++ F+ C F+ P
Sbjct: 144 FTLLFLTAVVQRITVHVTR--RPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI--P 199
Query: 238 AIIFKHIE-GWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAY 295
A +F +E W+ L++ YF I+L+TIG GDYV G G + ++ + YK + ++L+GL
Sbjct: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIA 259
Query: 296 FAAVL 300
VL
Sbjct: 260 MLVVL 264
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 135 bits (341), Expect = 5e-32
Identities = 85/277 (30%), Positives = 146/277 (52%), Gaps = 21/277 (7%)
Query: 53 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNS--T 108
MK + V T+ L+V YL++GA VF ALE E+ +R + +++Q ++++
Sbjct: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
Query: 109 ELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 168
EL+ ++ ++ AG+ W SF+FA TVITTIG+G+ +P T+GGK+
Sbjct: 61 ELERVVLRLKPH-KAGV-----------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKV 108
Query: 169 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 228
FC+ YALLGIPL + +G+++ T+ + + + + + + + + ++ F
Sbjct: 109 FCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGL---GMRRADVSMANMVLIGFF 165
Query: 229 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSD--IEYLDFYKPVVW 286
C+ + + A F H E W+ A Y+ ITLTTIGFGDYVA D ++ Y +
Sbjct: 166 SCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSF 225
Query: 287 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRA 323
+IL GL A L+++ ++ + ++ E RA
Sbjct: 226 VYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRA 262
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 134 bits (337), Expect = 2e-31
Identities = 83/241 (34%), Positives = 125/241 (51%), Gaps = 12/241 (4%)
Query: 68 YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIP 127
YL++GA + LE PHE R + + + + CV + LD +++++AA G +
Sbjct: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
Query: 128 LGNTSNQISH----WDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGF 183
L N S + WD S+ FFA T+ITT+G+G +P T+ GK F I +ALLG+P
Sbjct: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
Query: 184 LLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA--LPAIIF 241
LL +L + + V +++ R + L G V+ V +PA+IF
Sbjct: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
Query: 242 KHI-EGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYFAAV 299
H+ E WS LDA YF I+L+TIG GDYV G + + Y YK +V ++ +GL V
Sbjct: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
Query: 300 L 300
L
Sbjct: 253 L 253
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 132 bits (331), Expect = 8e-31
Identities = 75/209 (35%), Positives = 114/209 (54%), Gaps = 5/209 (2%)
Query: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
+ L + YL +G VF LE + K + +C++ LD LI+ +V A
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
G L NT++ + W+L SFFF+ + ITTIG+GN+SP T ++FCI +AL+GIPL
Sbjct: 85 YKNGASLLSNTTS-MGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPL 143
Query: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII 240
+L ++LG + +G+ K R ++ +L G +LF+ LP ++
Sbjct: 144 NLVVL----NRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLL 199
Query: 241 FKHIEGWSALDAIYFVVITLTTIGFGDYV 269
F H+EGWS + YF ITL+T+GFGDYV
Sbjct: 200 FSHMEGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 130 bits (326), Expect = 3e-30
Identities = 81/246 (32%), Positives = 129/246 (52%), Gaps = 17/246 (6%)
Query: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
+ L + YL++GA VF ALE E S R +++QK+ + + ++ + EL + + A
Sbjct: 11 LVLCTLCYLLVGAAVFDALESEAE-SGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
Query: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
W SF+FA TVITTIG+G+ +P T+ GK+FC+ YALLGIPL
Sbjct: 70 ---------EPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
Query: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTF-IKWNVSQTKIRIISTIIFILFGCVLFVALPAI 239
+G++L + + + + ++W T+ + ++ L C +AL A+
Sbjct: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTE----NLVVAGLLACAATLALGAV 176
Query: 240 IFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVWFWILVGLAYFA 297
F H EGW+ A Y+ ITLTTIGFGD+VA G ++ Y + +IL+GL
Sbjct: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
Query: 298 AVLSMI 303
A L+++
Sbjct: 237 AFLNLV 242
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 125 bits (315), Expect = 6e-29
Identities = 89/307 (28%), Positives = 151/307 (49%), Gaps = 25/307 (8%)
Query: 53 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTEL 110
MK + V T+ L+V YL++GA VF ALE HE+ + + ++ +++ ++S +
Sbjct: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYN-ISSEDY 59
Query: 111 DELIQQIVAAI--NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 168
+L I+ + AG+ W SF+FA TVITTIG+G+ +P T+ GK
Sbjct: 60 RQLELVILQSEPHRAGV-----------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKA 108
Query: 169 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 228
FC+ YA+LGIPL + +G+++ T + +++ + T + + + + F
Sbjct: 109 FCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKC---CGMRNTDVSMENMVTVGFF 165
Query: 229 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVW 286
C+ + + A F E WS A Y+ ITLTTIGFGDYVA ++ Y +
Sbjct: 166 SCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSF 225
Query: 287 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAA----EWTANVTAEFKETRRR 342
+ILVGL A L+++ ++ + + E RA A ++ E + +R R
Sbjct: 226 MYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPR 285
Query: 343 LSVEIYD 349
++ D
Sbjct: 286 YKADVPD 292
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 110 bits (276), Expect = 2e-24
Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)
Query: 55 WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 113
W + + +L L +GA VF+ALE P + + + F ++H +C+ L+EL
Sbjct: 7 WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
Query: 114 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173
+ +A G+ LGN+S + WDL S+ FA +++TT G+G+++P + GGK FC++Y
Sbjct: 67 LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
Query: 174 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 233
A LG+P L+A + L + + A V + W +S + ++ + L F
Sbjct: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
Query: 234 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 271
V LPA++ ++G S L A+YF +L+TIG D + G
Sbjct: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 110 bits (276), Expect = 2e-24
Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)
Query: 55 WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 113
W + + +L L +GA VF+ALE P + + + F ++H +C+ L+EL
Sbjct: 7 WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
Query: 114 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173
+ +A G+ LGN+S + WDL S+ FA +++TT G+G+++P + GGK FC++Y
Sbjct: 67 LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
Query: 174 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 233
A LG+P L+A + L + + A V + W +S + ++ + L F
Sbjct: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
Query: 234 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 271
V LPA++ ++G S L A+YF +L+TIG D + G
Sbjct: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 110 bits (276), Expect = 2e-24
Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)
Query: 55 WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 113
W + + +L L +GA VF+ALE P + + + F ++H +C+ L+EL
Sbjct: 7 WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
Query: 114 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173
+ +A G+ LGN+S + WDL S+ FA +++TT G+G+++P + GGK FC++Y
Sbjct: 67 LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
Query: 174 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 233
A LG+P L+A + L + + A V + W +S + ++ + L F
Sbjct: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
Query: 234 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 271
V LPA++ ++G S L A+YF +L+TIG D + G
Sbjct: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 110 bits (276), Expect = 2e-24
Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)
Query: 55 WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 113
W + + +L L +GA VF+ALE P + + + F ++H +C+ L+EL
Sbjct: 7 WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
Query: 114 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173
+ +A G+ LGN+S + WDL S+ FA +++TT G+G+++P + GGK FC++Y
Sbjct: 67 LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
Query: 174 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 233
A LG+P L+A + L + + A V + W +S + ++ + L F
Sbjct: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
Query: 234 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 271
V LPA++ ++G S L A+YF +L+TIG D + G
Sbjct: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 108 bits (271), Expect = 7e-24
Identities = 78/264 (29%), Positives = 122/264 (46%), Gaps = 34/264 (12%)
Query: 64 VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 123
++ LYL+ GATVF ALE P E R + F + H V EL ++ AA+ A
Sbjct: 45 LIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHYEAALAA 103
Query: 124 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG------ 177
G+ WD +F+F GTV++TIGFG +P T GGK F I Y L G
Sbjct: 104 GV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTIL 159
Query: 178 ---------IPLFGFLLAGVGDQ-------LGTIFGKGIAKVE-DTFIKWNVSQTKIRII 220
I L F++ ++ L F +G A E D+ W S + +I
Sbjct: 160 FFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLI 219
Query: 221 STIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLD 279
+ +L C + ++ +EGW +D++YF +T +TIGFGD V+ +
Sbjct: 220 LGLFAVLLSC-----CASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
Query: 280 FYKPVVWFWILVGLAYFAAVLSMI 303
Y+ + +IL+G+ ++ ++I
Sbjct: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 102 bits (253), Expect = 9e-22
Identities = 81/268 (30%), Positives = 121/268 (45%), Gaps = 42/268 (15%)
Query: 64 VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 123
++VLYL+ GA VF ALE HE + + F H+ ++ EL ++ A A
Sbjct: 26 LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
Query: 124 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG----IP 179
GI N WD +F+F GTV++TIGFG +P T GGKIF I Y L+G I
Sbjct: 85 GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
Query: 180 LFGFLLAGVGDQLGTIFG-------------KGIAKVE----------DTFIKWNVSQTK 216
F L ++L TI +G E D+ W S
Sbjct: 141 FFNLFL----ERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYY 196
Query: 217 IRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDI 275
+ +I IL C + ++ IEGWS D++YF + +TIGFGD V+ +
Sbjct: 197 VMLILCTASILISC-----CASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
Query: 276 EYLDFYKPVVWFWILVGLAYFAAVLSMI 303
E Y+ + +IL+G+ ++ ++I
Sbjct: 252 ESQGLYRFANFVFILMGVCCIYSLFNVI 279
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 65 VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCV---NSTELDELIQQIVAAI 121
+V Y ++GA VF A+E + +K F+ + + + T +++ Q + +
Sbjct: 30 LVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETVVEDRKQDLQGHL 87
Query: 122 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 181
+ P N+ +HW SS FF TV +T+G+G I P T GK C++YAL GIPL
Sbjct: 88 QK-VKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLM 144
Query: 182 GFLLAGVGDQLGTI 195
+L GD L TI
Sbjct: 145 FLVLTDTGDILATI 158
Score = 32.7 bits (73), Expect = 0.64
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 31/127 (24%)
Query: 80 EQPHEISQRTTIVIQKQTFISQHSCVNS----------TELDELIQQ---------IVAA 120
E+ H + ++ T+ + Q +SC + LDE+ QQ I+A
Sbjct: 229 ERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIAL 288
Query: 121 I-------NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173
I A I+P T D ++F+F +TTIGFG+ +F IY
Sbjct: 289 IVFAYISCAAAILPFWETQ-----LDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIY 343
Query: 174 ALLGIPL 180
++G+ +
Sbjct: 344 IIVGMEI 350
Score = 31.2 bits (69), Expect = 1.9
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 6/43 (13%)
Query: 251 DAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGL 293
+A YF +TLTTIGFGD V +E+ +F+ +I+VG+
Sbjct: 312 NAFYFCFVTLTTIGFGDTV-----LEHPNFFL-FFSIYIIVGM 348
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 12/91 (13%)
Query: 106 NSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLG--------SSFFFAGTVITTIGFG 157
N+ ++D + Q+ A++ G NTS I W+ G SS +F T +TTIGFG
Sbjct: 381 NTIQIDSWLYQL--ALSIGTPYRYNTSAGI--WEGGPSKDSLYVSSLYFTMTSLTTIGFG 436
Query: 158 NISPRTEGGKIFCIIYALLGIPLFGFLLAGV 188
NI+P T+ K+F + ++G L+ + V
Sbjct: 437 NIAPTTDVEKMFSVAMMMVGSLLYATIFGNV 467
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 12/91 (13%)
Query: 106 NSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLG--------SSFFFAGTVITTIGFG 157
N+ ++D + Q+ A++ G NTS I W+ G SS +F T +TTIGFG
Sbjct: 323 NTIQIDSWLYQL--ALSIGTPYRYNTSAGI--WEGGPSKDSLYVSSLYFTMTSLTTIGFG 378
Query: 158 NISPRTEGGKIFCIIYALLGIPLFGFLLAGV 188
NI+P T+ K+F + ++G L+ + V
Sbjct: 379 NIAPTTDVEKMFSVAMMMVGSLLYATIFGNV 409
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 12/91 (13%)
Query: 106 NSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLG--------SSFFFAGTVITTIGFG 157
N+ ++D + Q+ A++ G NTS I W+ G SS +F T +TTIGFG
Sbjct: 381 NTIQIDSWLYQL--ALSIGTPYRYNTSAGI--WEGGPSKDSLYVSSLYFTMTSLTTIGFG 436
Query: 158 NISPRTEGGKIFCIIYALLGIPLFGFLLAGV 188
NI+P T+ K+F + ++G L+ + V
Sbjct: 437 NIAPTTDVEKMFSVAMMMVGSLLYATIFGNV 467
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 41.2 bits (95), Expect = 0.002
Identities = 18/47 (38%), Positives = 29/47 (61%)
Query: 142 SSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGV 188
SS +F T +T++GFGNI+P T+ KIF + ++G L+ + V
Sbjct: 425 SSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNV 471
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,876,011
Number of Sequences: 37866
Number of extensions: 534889
Number of successful extensions: 1655
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1396
Number of HSP's gapped (non-prelim): 176
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.