BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62526045 zinc finger protein 638 [Homo sapiens] (1978 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62526045 zinc finger protein 638 [Homo sapiens] 3895 0.0 gi|21626468 zinc finger protein 638 [Homo sapiens] 3895 0.0 gi|62750354 matrin 3 [Homo sapiens] 72 4e-12 gi|21626466 matrin 3 [Homo sapiens] 72 4e-12 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 65 9e-10 gi|87299628 biorientation of chromosomes in cell division 1-like... 62 7e-09 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 62 7e-09 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 62 7e-09 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 62 7e-09 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 61 9e-09 gi|116812577 LUC7-like 2 [Homo sapiens] 61 9e-09 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 60 2e-08 gi|197276594 RNA binding motif protein 20 [Homo sapiens] 59 6e-08 gi|109637759 calpastatin isoform f [Homo sapiens] 58 1e-07 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 56 4e-07 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 9e-07 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 54 2e-06 gi|62244004 modulator of estrogen induced transcription isoform ... 54 2e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 52 6e-06 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 52 6e-06 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 6e-06 gi|104526627 triadin [Homo sapiens] 52 6e-06 gi|221219020 NYD-SP11 protein [Homo sapiens] 52 8e-06 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 52 8e-06 gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 51 1e-05 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 51 1e-05 gi|109637771 calpastatin isoform l [Homo sapiens] 51 1e-05 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 1e-05 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 1e-05 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 50 2e-05 >gi|62526045 zinc finger protein 638 [Homo sapiens] Length = 1978 Score = 3895 bits (10102), Expect = 0.0 Identities = 1978/1978 (100%), Positives = 1978/1978 (100%) Query: 1 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES 60 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES Sbjct: 1 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES 60 Query: 61 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS 120 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS Sbjct: 61 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS 120 Query: 121 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR 180 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR Sbjct: 121 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR 180 Query: 181 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN 240 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN Sbjct: 181 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN 240 Query: 241 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG 300 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG Sbjct: 241 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG 300 Query: 301 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS 360 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS Sbjct: 301 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS 360 Query: 361 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS 420 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS Sbjct: 361 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS 420 Query: 421 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE 480 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE Sbjct: 421 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE 480 Query: 481 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR 540 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR Sbjct: 481 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR 540 Query: 541 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA 600 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA Sbjct: 541 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA 600 Query: 601 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV 660 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV Sbjct: 601 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV 660 Query: 661 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME 720 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME Sbjct: 661 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME 720 Query: 721 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA 780 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA Sbjct: 721 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA 780 Query: 781 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK 840 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK Sbjct: 781 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK 840 Query: 841 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE 900 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE Sbjct: 841 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE 900 Query: 901 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY 960 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY Sbjct: 901 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY 960 Query: 961 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG 1020 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG Sbjct: 961 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG 1020 Query: 1021 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS 1080 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS Sbjct: 1021 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS 1080 Query: 1081 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL 1140 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL Sbjct: 1081 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL 1140 Query: 1141 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL Sbjct: 1141 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 Query: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE 1260 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE Sbjct: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE 1260 Query: 1261 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET 1320 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET Sbjct: 1261 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET 1320 Query: 1321 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS 1380 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS Sbjct: 1321 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS 1380 Query: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL 1440 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL Sbjct: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL 1440 Query: 1441 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM 1500 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM Sbjct: 1441 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM 1500 Query: 1501 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP 1560 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP Sbjct: 1501 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP 1560 Query: 1561 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT 1620 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT Sbjct: 1561 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT 1620 Query: 1621 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL 1680 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL Sbjct: 1621 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL 1680 Query: 1681 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ 1740 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ Sbjct: 1681 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ 1740 Query: 1741 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND 1800 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND Sbjct: 1741 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND 1800 Query: 1801 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK 1860 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK Sbjct: 1801 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK 1860 Query: 1861 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD 1920 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD Sbjct: 1861 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD 1920 Query: 1921 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR 1978 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR Sbjct: 1921 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR 1978 >gi|21626468 zinc finger protein 638 [Homo sapiens] Length = 1978 Score = 3895 bits (10102), Expect = 0.0 Identities = 1978/1978 (100%), Positives = 1978/1978 (100%) Query: 1 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES 60 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES Sbjct: 1 MSRPRFNPRGDFPLQRPRAPNPSGMRPPGPFMRPGSMGLPRFYPAGRARGIPHRFAGHES 60 Query: 61 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS 120 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS Sbjct: 61 YQNMGPQRMNVQVTQHRTDPRLTKEKLDFHEAQQKKGKPHGSRWDDEPHISASVAVKQSS 120 Query: 121 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR 180 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR Sbjct: 121 VTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMR 180 Query: 181 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN 240 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN Sbjct: 181 KMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVEN 240 Query: 241 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG 300 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG Sbjct: 241 EFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISG 300 Query: 301 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS 360 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS Sbjct: 301 GQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSS 360 Query: 361 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS 420 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS Sbjct: 361 NVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAAS 420 Query: 421 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE 480 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE Sbjct: 421 PRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKE 480 Query: 481 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR 540 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR Sbjct: 481 NETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR 540 Query: 541 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA 600 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA Sbjct: 541 SPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAA 600 Query: 601 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV 660 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV Sbjct: 601 DKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAV 660 Query: 661 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME 720 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME Sbjct: 661 SLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEME 720 Query: 721 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA 780 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA Sbjct: 721 FKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADA 780 Query: 781 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK 840 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK Sbjct: 781 SKAVEIVTSTSAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKK 840 Query: 841 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE 900 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE Sbjct: 841 SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKE 900 Query: 901 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY 960 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY Sbjct: 901 TEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFY 960 Query: 961 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG 1020 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG Sbjct: 961 TCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDG 1020 Query: 1021 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS 1080 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS Sbjct: 1021 LQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLS 1080 Query: 1081 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL 1140 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL Sbjct: 1081 PKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETL 1140 Query: 1141 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL Sbjct: 1141 VQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 Query: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE 1260 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE Sbjct: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE 1260 Query: 1261 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET 1320 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET Sbjct: 1261 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET 1320 Query: 1321 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS 1380 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS Sbjct: 1321 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS 1380 Query: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL 1440 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL Sbjct: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL 1440 Query: 1441 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM 1500 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM Sbjct: 1441 KPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIM 1500 Query: 1501 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP 1560 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP Sbjct: 1501 KRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNP 1560 Query: 1561 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT 1620 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT Sbjct: 1561 LKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVT 1620 Query: 1621 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL 1680 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL Sbjct: 1621 VDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERL 1680 Query: 1681 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ 1740 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ Sbjct: 1681 VTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQ 1740 Query: 1741 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND 1800 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND Sbjct: 1741 DDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKND 1800 Query: 1801 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK 1860 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK Sbjct: 1801 HPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGK 1860 Query: 1861 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD 1920 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD Sbjct: 1861 TLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD 1920 Query: 1921 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR 1978 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR Sbjct: 1921 FLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR 1978 >gi|62750354 matrin 3 [Homo sapiens] Length = 847 Score = 72.4 bits (176), Expect = 4e-12 Identities = 90/400 (22%), Positives = 167/400 (41%), Gaps = 38/400 (9%) Query: 921 EVYDLAKPFGGLKDILILSSHKKAYIEI-NRKAAESMVKFYTCFPVLMDGNQLSISMAPE 979 ++ L +PFG + + LIL+ +A+IE+ + A++ V +YT P L+ G + + ++ + Sbjct: 414 QLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQK 473 Query: 980 NMNIKDEEAIFITLVKENDPEANIDTIYD--RFVHLDNLPEDGL--QCVLCVGLQFGKVD 1035 IK E P+ D + R +HL NLP G VL + +GK+ Sbjct: 474 YKRIKK---------PEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIK 524 Query: 1036 HHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQI-EHDP 1094 +++ + +++A +++++ E A +M + + LS K ++I Sbjct: 525 NYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGI 584 Query: 1095 ELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKA 1154 +L K+ K S + + +SPS K ++ + TE +QEE E+ EK Sbjct: 585 DLLKKDKSRKRSYSPDGK-----ESPSDKKSKTDGSQKTESSTEG-KEQEEKSGEDGEKD 638 Query: 1155 TCDSDFAVE-TLELETQGEEVKEE----IPLVASASVSIEQFTENAEECALNQQMFNSD- 1208 T D E + LE++ E + +E L + +SV E N + A + + SD Sbjct: 639 TKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDK 698 Query: 1209 -LEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGI----------TQT 1257 ++K G+ K L D + ++ + LE E+ G T Sbjct: 699 AVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDT 758 Query: 1258 MVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDK 1297 A + ++N+ I I P +P G + + K Sbjct: 759 SENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPK 798 Score = 70.5 bits (171), Expect = 2e-11 Identities = 63/246 (25%), Positives = 107/246 (43%), Gaps = 56/246 (22%) Query: 1781 GEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQVGP----VNEN--- 1833 G+E D K + +Q K + T+ K +K D +K + ++ P +E+ Sbjct: 601 GKESPSDKKSKTDGSQ-KTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELL 659 Query: 1834 VMEEDLKTMIERHLTAKTPTKRVRIG------KTLPSEKAVVTEPA-------------K 1874 V EE+ ++E + T +G K PS+KAV + + K Sbjct: 660 VDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDK 719 Query: 1875 GEEAFQMSEVDEESGLKDSE-----------PERKRKKTEDSSSGKSVAS---------- 1913 EE Q +E E+G+K+ E + K T +++ G+S + Sbjct: 720 IEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEY 779 Query: 1914 -------DVPEELDFLVPKAGFFCPICSLFYSGEKAMTN-HCKSTRHKQNTEKFMAKQRK 1965 +VP +D+++PK GF+C +CSLFY+ E+ N HC S H Q +KF+ K + Sbjct: 780 RIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAE 839 Query: 1966 EKEQNE 1971 E+ Q + Sbjct: 840 ERRQKK 845 Score = 64.7 bits (156), Expect = 9e-10 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 5/92 (5%) Query: 402 QKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQY 461 +K + P S + D++ P+ +PHLCS+C++ K+W QH N ++H C+ L + Y Sbjct: 267 EKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIY 326 Query: 462 PDWNPEILPSRRNEGNRKENETPRRRSHSPSP 493 P+WNP+ + G+ + ++S +P+P Sbjct: 327 PEWNPD-----NDTGHTMGDPFMLQQSTNPAP 353 Score = 60.8 bits (146), Expect = 1e-08 Identities = 28/50 (56%), Positives = 39/50 (78%) Query: 132 QSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRK 181 Q R + AS+ILASFGLS DL+ELSRYP++++TPEN+P IL ++ R+ Sbjct: 100 QHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRR 149 Score = 59.3 bits (142), Expect = 4e-08 Identities = 59/272 (21%), Positives = 113/272 (41%), Gaps = 37/272 (13%) Query: 669 EQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAI 728 +Q G V+ ++ LP G ++ V KL +P+GK+ + +++ + +A++EME +E A+ Sbjct: 489 DQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAM 548 Query: 729 MKYIETTPLTIKGKSVKICVPGKKK--------------AQNKEVKKKTLESKKVSASTL 774 + + L +G+ VK+ + K K ++K K+ K S S Sbjct: 549 VDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDK 608 Query: 775 KRDADASKAVEIVT--STSAAKTGQAKASVAKVNKS-----------------TGKSASS 815 K D S+ E T K+G+ K +++ ++A+ Sbjct: 609 KSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAAL 668 Query: 816 VKSVVTVAVKGNKASIKTAKSGGKK---SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIE 872 ++S +V + + A++ S GKK KK G+ K + + E+ E Sbjct: 669 LESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENE 728 Query: 873 VKATENCAKEAISDAALEATEN-EPLNKETEE 903 E ++ E++EN + NK+T E Sbjct: 729 AALENGIKNEENTEPGAESSENADDPNKDTSE 760 Score = 42.4 bits (98), Expect = 0.005 Identities = 23/69 (33%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Query: 890 EATENEPLNKETEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEI- 948 E ++ +++ E V+ +SNLP+ GYS V LA+P+G +K+ +++ +A+IE+ Sbjct: 481 EGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEME 540 Query: 949 NRKAAESMV 957 R+ A +MV Sbjct: 541 TREDAMAMV 549 Score = 40.8 bits (94), Expect = 0.013 Identities = 22/63 (34%), Positives = 35/63 (55%) Query: 695 KLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIETTPLTIKGKSVKICVPGKKKA 754 +L +PFG +++ LI+ EA++EM E A + Y TTP + GK V++ + K K Sbjct: 417 QLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKR 476 Query: 755 QNK 757 K Sbjct: 477 IKK 479 >gi|21626466 matrin 3 [Homo sapiens] Length = 847 Score = 72.4 bits (176), Expect = 4e-12 Identities = 90/400 (22%), Positives = 167/400 (41%), Gaps = 38/400 (9%) Query: 921 EVYDLAKPFGGLKDILILSSHKKAYIEI-NRKAAESMVKFYTCFPVLMDGNQLSISMAPE 979 ++ L +PFG + + LIL+ +A+IE+ + A++ V +YT P L+ G + + ++ + Sbjct: 414 QLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQK 473 Query: 980 NMNIKDEEAIFITLVKENDPEANIDTIYD--RFVHLDNLPEDGL--QCVLCVGLQFGKVD 1035 IK E P+ D + R +HL NLP G VL + +GK+ Sbjct: 474 YKRIKK---------PEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIK 524 Query: 1036 HHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQI-EHDP 1094 +++ + +++A +++++ E A +M + + LS K ++I Sbjct: 525 NYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGI 584 Query: 1095 ELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKA 1154 +L K+ K S + + +SPS K ++ + TE +QEE E+ EK Sbjct: 585 DLLKKDKSRKRSYSPDGK-----ESPSDKKSKTDGSQKTESSTEG-KEQEEKSGEDGEKD 638 Query: 1155 TCDSDFAVE-TLELETQGEEVKEE----IPLVASASVSIEQFTENAEECALNQQMFNSD- 1208 T D E + LE++ E + +E L + +SV E N + A + + SD Sbjct: 639 TKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDK 698 Query: 1209 -LEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGI----------TQT 1257 ++K G+ K L D + ++ + LE E+ G T Sbjct: 699 AVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDT 758 Query: 1258 MVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDK 1297 A + ++N+ I I P +P G + + K Sbjct: 759 SENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPK 798 Score = 70.5 bits (171), Expect = 2e-11 Identities = 63/246 (25%), Positives = 107/246 (43%), Gaps = 56/246 (22%) Query: 1781 GEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQVGP----VNEN--- 1833 G+E D K + +Q K + T+ K +K D +K + ++ P +E+ Sbjct: 601 GKESPSDKKSKTDGSQ-KTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELL 659 Query: 1834 VMEEDLKTMIERHLTAKTPTKRVRIG------KTLPSEKAVVTEPA-------------K 1874 V EE+ ++E + T +G K PS+KAV + + K Sbjct: 660 VDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDK 719 Query: 1875 GEEAFQMSEVDEESGLKDSE-----------PERKRKKTEDSSSGKSVAS---------- 1913 EE Q +E E+G+K+ E + K T +++ G+S + Sbjct: 720 IEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEY 779 Query: 1914 -------DVPEELDFLVPKAGFFCPICSLFYSGEKAMTN-HCKSTRHKQNTEKFMAKQRK 1965 +VP +D+++PK GF+C +CSLFY+ E+ N HC S H Q +KF+ K + Sbjct: 780 RIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAE 839 Query: 1966 EKEQNE 1971 E+ Q + Sbjct: 840 ERRQKK 845 Score = 64.7 bits (156), Expect = 9e-10 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 5/92 (5%) Query: 402 QKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQY 461 +K + P S + D++ P+ +PHLCS+C++ K+W QH N ++H C+ L + Y Sbjct: 267 EKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIY 326 Query: 462 PDWNPEILPSRRNEGNRKENETPRRRSHSPSP 493 P+WNP+ + G+ + ++S +P+P Sbjct: 327 PEWNPD-----NDTGHTMGDPFMLQQSTNPAP 353 Score = 60.8 bits (146), Expect = 1e-08 Identities = 28/50 (56%), Positives = 39/50 (78%) Query: 132 QSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRK 181 Q R + AS+ILASFGLS DL+ELSRYP++++TPEN+P IL ++ R+ Sbjct: 100 QHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRR 149 Score = 59.3 bits (142), Expect = 4e-08 Identities = 59/272 (21%), Positives = 113/272 (41%), Gaps = 37/272 (13%) Query: 669 EQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAI 728 +Q G V+ ++ LP G ++ V KL +P+GK+ + +++ + +A++EME +E A+ Sbjct: 489 DQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAM 548 Query: 729 MKYIETTPLTIKGKSVKICVPGKKK--------------AQNKEVKKKTLESKKVSASTL 774 + + L +G+ VK+ + K K ++K K+ K S S Sbjct: 549 VDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDK 608 Query: 775 KRDADASKAVEIVT--STSAAKTGQAKASVAKVNKS-----------------TGKSASS 815 K D S+ E T K+G+ K +++ ++A+ Sbjct: 609 KSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAAL 668 Query: 816 VKSVVTVAVKGNKASIKTAKSGGKK---SLEAKKTGNVKNKDSNKPVTIPENSEIKTSIE 872 ++S +V + + A++ S GKK KK G+ K + + E+ E Sbjct: 669 LESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENE 728 Query: 873 VKATENCAKEAISDAALEATEN-EPLNKETEE 903 E ++ E++EN + NK+T E Sbjct: 729 AALENGIKNEENTEPGAESSENADDPNKDTSE 760 Score = 42.4 bits (98), Expect = 0.005 Identities = 23/69 (33%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Query: 890 EATENEPLNKETEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEI- 948 E ++ +++ E V+ +SNLP+ GYS V LA+P+G +K+ +++ +A+IE+ Sbjct: 481 EGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEME 540 Query: 949 NRKAAESMV 957 R+ A +MV Sbjct: 541 TREDAMAMV 549 Score = 40.8 bits (94), Expect = 0.013 Identities = 22/63 (34%), Positives = 35/63 (55%) Query: 695 KLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIETTPLTIKGKSVKICVPGKKKA 754 +L +PFG +++ LI+ EA++EM E A + Y TTP + GK V++ + K K Sbjct: 417 QLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKR 476 Query: 755 QNK 757 K Sbjct: 477 IKK 479 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 64.7 bits (156), Expect = 9e-10 Identities = 166/913 (18%), Positives = 360/913 (39%), Gaps = 136/913 (14%) Query: 1042 NRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPE----LE 1097 ++ + LQ + + + L+Q + IGD KI E ++ E LE Sbjct: 490 HQEQQALQQSTTAKLREAQNDLEQVLRQIGDK------DQKIQNLEALLQKSKENISLLE 543 Query: 1098 KESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCD 1157 KE L + I E +TA + + N +E + TE L Q E ++ E Sbjct: 544 KEREDLY-AKIQAGEGETAVLNQLQEKNHTLQEQVTQL-TEKLKNQSESHKQAQEN---- 597 Query: 1158 SDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEI- 1216 L Q +E K + +S+E LN Q+ S + +I Sbjct: 598 ---------LHDQVQEQKAHLRAAQDRVLSLETSVNE-----LNSQLNESKEKVSQLDIQ 643 Query: 1217 INPKTALLPSDSVF--AEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEI 1274 I KT LL S A+ +L+ L+ + + +D K + +++I Sbjct: 644 IKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD-----------------KQQELNKI 686 Query: 1275 LPSTCIVTLVPGIPTGDEKTVDKK-NISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEK 1333 VT K DK+ + S+ + ++ E +EK + ++ +L+ +K E Sbjct: 687 TTQLDQVTA---------KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEA 737 Query: 1334 NEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPS 1393 + + A K + + ++++ NT + + Q E ++ L + S + S Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797 Query: 1394 IKAVIVSSPKAKATVSKTENQKSFPKSVPRDQIN---------AEKKLSAKEFGLLKPTS 1444 IK + + K + + S + +++N +K KE + + ++ Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELST 857 Query: 1445 ARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQ-------------SQ 1491 + L++ S K ++S + +GK + LD K+ + Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQ------KGKAAILDLEKTCKELKHQLQVQMENTLKE 911 Query: 1492 ETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSS---KSKEEPLFPFNLDEFVT----- 1543 + E + S+ K +++++ E N+ + +++ KEE N++E Sbjct: 912 QKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQK 971 Query: 1544 ---VDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVT 1600 ++ + E+ + ++ L+ K ++ L EL +K+K + + +F Sbjct: 972 KKQIEALQGELKIAVLQKTELENKLQQQLTQAA-QELAAEKEKISVLQNNYEKSQETFKQ 1030 Query: 1601 L--DEIGEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELI--------- 1649 L D G E + A Q L +V+E + L E+++ N N + ++LI Sbjct: 1031 LQSDFYGRESELLA-TRQDLKSVEEKLS---LAQEDLISNRNQIGNQNKLIQELKTAKAT 1086 Query: 1650 -DQDDCISHSEPKD--VTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESADITFATLN 1706 +QD + ++ + + +E+ L ++E + ++ E+EE+ + +IT Sbjct: 1087 LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE 1146 Query: 1707 TKGNEGDTV------RDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTLDEVTEEDED 1760 K ++ +++ +D+ + Q E ++ + + D+V +E+E+ Sbjct: 1147 LKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206 Query: 1761 SLADFNNLKEELNF-VTVDEVGEEEDGDNDLKVEL---AQSKNDHPTDKKGNRKKRAVDT 1816 +F + +L+ + EVG ++ +N+ K+ + A ++N K+ +R V Sbjct: 1207 LKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSE 1266 Query: 1817 KKTKLESL-SQVGPVNENVM--EEDLKTMIERHLTA-----KTPTKRVRIGKTLPSEKAV 1868 + + + L ++ + V +++ + ++ER L K TK + + + L + A Sbjct: 1267 LEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAA 1326 Query: 1869 VTEPAKGEEAFQM 1881 V E + ++ Q+ Sbjct: 1327 VQELGRENQSLQI 1339 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 61.6 bits (148), Expect = 7e-09 Identities = 206/1001 (20%), Positives = 369/1001 (36%), Gaps = 120/1001 (11%) Query: 1060 YSFLKQNPQN-IGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATD 1118 Y L+Q N + +H+ T + SP ++ + Q+ ++ + G+ S ID Q Sbjct: 84 YQNLRQRVDNFVANHLATHTWSPHLN--KNQLRNNIRQQVLKSGMLESGIDRIISQVVDP 141 Query: 1119 SPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEI 1178 K N E L +EE T D +T L TQG Sbjct: 142 ----KINHTFRPQVEKAVHEFLATLNH--KEEGSGNTAPDDEKPDT-SLITQGVPTPGPS 194 Query: 1179 PLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTALLPS-DSVFAEERNLK 1237 VA+ ++SI + + + A + K +E + K P+ D+ +ER + Sbjct: 195 ANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSE 254 Query: 1238 GILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTV-- 1295 + ++ S A+ SG E + K+E S++ C V + + Sbjct: 255 DMADKEKSTAD---SG-----GEGLETAPKSEEFSDL---PCPVEEIKNYTKEHNNLILL 303 Query: 1296 ---DKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEK----NEGRMDAEKVEKMAA 1348 ++ SE+K +K EK+ ++ E + EK EK ++ D +KV+ Sbjct: 304 NKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQ 363 Query: 1349 MKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATV 1408 KEK E+ K K +A + T + L SDV I V + + Sbjct: 364 AKEKEVES--LKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLT-DITVSSVHTSDLSSFE 420 Query: 1409 SKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKF----KP-TQSSL 1463 TE + S+ +I ++ + K+ TS S S + KP S Sbjct: 421 EDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKY 480 Query: 1464 TRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKST-T 1522 ++ Q + S I K+ +E R I + + + TK+ K+ Sbjct: 481 YSDSDDELTVEQRRQS------IAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQ 534 Query: 1523 GRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKK 1582 GRSS EE + + EV++E + K+ L KRK+ +NV E N KKK Sbjct: 535 GRSSVDLEESSTKSLEPKAARIKEVLKERKVLE-KKVALSKKRKKDSRNV---EENSKKK 590 Query: 1583 KG---------KTSTPRGVEGELSFVTLDEI---GEEEDAAAHLAQALVTVDEVIDEEEL 1630 + KTS E S L + E A L+++L VDE +E +L Sbjct: 591 QQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKL 650 Query: 1631 NMEEMVKNSNSLFT--LDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVD---- 1684 E + S + + E D D E ++ +++ LK E+ + D Sbjct: 651 EREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSET 710 Query: 1685 ---------EIGEVEELPLNE---SADITFATLNTKGNEGDTVRDSIGFISSQVPEDPST 1732 E+ +E P E S D KG+ D SS+ Sbjct: 711 PHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSE-----KG 765 Query: 1733 LVTVDEIQDDSSDLHLVTLDEVTEEDED------SLADFNNLKEELNFVTVDEVGEEEDG 1786 L + IQ S L + D+ + + S+ + + DE +E+ Sbjct: 766 LKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENN 825 Query: 1787 DNDLKVELAQSKNDHPTDKKGNRK--KRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIE 1844 + ++ ++K +H + + + K K ++ +K+ + + +E+ + D M Sbjct: 826 KKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDS 885 Query: 1845 RHLTAKTPTKRVRIGKTLPSEKAVVTEPAK--GEEAFQMSEVDEESGLKDSEPER--KRK 1900 + K R K+L EK V+ +K G++ + +E K + + K K Sbjct: 886 NLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEK 945 Query: 1901 KTEDSSSGKSVASDVPEE------LDFLVPKAGFFC-------------PICSLFYSGEK 1941 TE++ S K S V ++ ++ ++ A P+ Y +K Sbjct: 946 NTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDK 1005 Query: 1942 AMTN----HCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR 1978 T+ S HK + K +K K+K++N+++++ + Sbjct: 1006 DSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGK 1046 Score = 38.5 bits (88), Expect = 0.066 Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 24/194 (12%) Query: 1736 VDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELA 1795 ++E+ SS+ + T + E+DE S ++ K E N D+ + ++ D + ++ Sbjct: 2818 LEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQND---DDTIKSQEEDQPIIIKR- 2873 Query: 1796 QSKNDHPTDKKGNRKKRAVDTK-KTKLESLSQVG--PVNENVMEEDLKTMIERHLTAKTP 1852 K+G +K V+T K K +S + G V ++ LK M +T Sbjct: 2874 ---------KRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETA 2924 Query: 1853 TKRVR-IGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKT-----EDSS 1906 + R I EK V + +G + + V +++ + SEPERKR+K+ ED Sbjct: 2925 NLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDA--ESSEPERKRQKSVSDPVEDKK 2982 Query: 1907 SGKSVASDVPEELD 1920 +S + EE D Sbjct: 2983 EQESDEEEEEEEED 2996 Score = 37.7 bits (86), Expect = 0.11 Identities = 108/578 (18%), Positives = 204/578 (35%), Gaps = 75/578 (12%) Query: 1091 EHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEE---STPSIQTETLVQQEEPC 1147 +++ +LE+E ++P+ VQ TD+ VK E P Q TL ++ Sbjct: 645 KNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLK 704 Query: 1148 EEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNS 1207 ++++E S E + + E +E+ P SV + + + ++ +S Sbjct: 705 KDDSETPHLKSLLKKEVKSSKEKPE--REKTPSEDKLSVKHKYKGDCMHKTGDETELHSS 762 Query: 1208 DLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEK 1267 + K E I ++ S ER K E S +++ +++ V K Sbjct: 763 EKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRK 822 Query: 1268 NETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNM------DEKEEKEFNTKETR 1321 E S + + K ++ K+ + + E + + T Sbjct: 823 ENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTN 882 Query: 1322 MDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSI 1381 MD + E+ E R +E+ +K K +K G+ K ET + Sbjct: 883 MDSNLKPEEVVHKEKRRTKSLLEEKLVLKSK-----------SKTQGKQVKVVET-ELQE 930 Query: 1382 LAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKL---SAKEFG 1438 A ++ KP + + K SK E++ P ++ E L S+ Sbjct: 931 GATKQATTPKPDKEKNTEENDSEKQRKSKVEDK-------PFEETGVEPVLETASSSAHS 983 Query: 1439 LLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPS 1498 K +S R+ L + K+K + S + + L+ KLS K S + + Sbjct: 984 TQKDSSHRAKLPLAKEKYKSDKDSTS-------TRLERKLSDGHKSRSLKHSSKDIKKKD 1036 Query: 1499 IMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQ 1558 K DD + K + + K G SS +++ + + E Q Sbjct: 1037 ENKSDDKDGKEVDSSHEK----ARGNSSLMEKK------------LSRRLCENRRGSLSQ 1080 Query: 1559 NPLKGKRK---ETLKNVPFSELNLKKKKGKTS-----TPRGVEGELSFVTLDEIGEEEDA 1610 KG+ K TL S L KK G + P ++ E + E+ + +D Sbjct: 1081 EMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDN 1140 Query: 1611 AAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDEL 1648 + +Q ++++ E M + +++ DEL Sbjct: 1141 RNNNSQ-----------QDIDSENMKQKTSATVQKDEL 1167 Score = 31.6 bits (70), Expect = 8.1 Identities = 48/233 (20%), Positives = 91/233 (39%), Gaps = 36/233 (15%) Query: 1481 LDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDE 1540 LD R T Q Q E P K ++S + + + STT R + K DE Sbjct: 2791 LDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEK---------DE 2841 Query: 1541 FVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVT 1600 + + + E+ P Q + +K + ++ + +K+K+G+ PR E + Sbjct: 2842 YSSSETTGEK--PEQNDDDTIKSQEED-------QPIIIKRKRGR---PRKYPVETTLKM 2889 Query: 1601 LDEIGEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEP 1660 D+ + +VTV++ +L + + +++ L Q+ IS+ + Sbjct: 2890 KDD--------SKTDTGIVTVEQSPSSSKLKVMQTDESNKETANL-----QERSISNDDG 2936 Query: 1661 KDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGD 1713 ++ V SV K +R +TV + E E ++ + K E D Sbjct: 2937 EEKIVTSVRRRG--RKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESD 2987 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 61.6 bits (148), Expect = 7e-09 Identities = 226/1161 (19%), Positives = 411/1161 (35%), Gaps = 191/1161 (16%) Query: 471 SRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFI 530 S R+ + RS+S SP RR R RSRS H +R RSRSP Sbjct: 675 STRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPP-----Y 729 Query: 531 SRYRSRSRSRSPYRIRNP-FRGSPK---------CFRSVSPE-RMSRRSVRSSDRKKALE 579 RY SRSRS +R ++P R P+ +R V P M RS D + E Sbjct: 730 RRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFE 789 Query: 580 DVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKP-----------SVKPTSATKS 628 R E ++ E KG++ +P+ S+ + P + + Sbjct: 790 KERYRE---WERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRR 846 Query: 629 DSNLGGHSIRCKS--------------KNLEDDTLSECKQ----VSDKAVSLQRKLRKEQ 670 + +GG S R ++ N +D+T S+ K+ D + +K RK + Sbjct: 847 EDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRR 906 Query: 671 SLHYGSVLLITELPEDGCTEEDVRKLFQPFG----KVNDVLIVPYRKEAY-LEMEFKEAI 725 L EL E RK +P G K + + ++P R +A + E +A Sbjct: 907 KGEESEGFLNPELLETS------RKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE 960 Query: 726 TAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADASKAVE 785 + K + + K K+K V KK K K D + ++ Sbjct: 961 SITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR 1020 Query: 786 IVTSTSAAKTGQAKASVAKVNKSTGK------------SASSVKSVVTVAVKGNKASIKT 833 AK K K + S+ K S S+ + T VK K Sbjct: 1021 SEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1080 Query: 834 AKSGGKKSLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATE 893 +K + L K+ K + NKP+ + + E ++ ++ + LE TE Sbjct: 1081 SKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE 1140 Query: 894 ------NEPLNKETEEM----------------CVMLVSNLPNKGYSVEEVYDLAKPFGG 931 + +TE+M + L K S E + + +P Sbjct: 1141 IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK 1200 Query: 932 LKDILILSSHKKAYIEINRKAAESMVKFYTCFPVLMDGNQLSISMAPENMNIKDEEAIFI 991 L+ +K ++ RK + T L+D S S + K EE Sbjct: 1201 LESTSSKVKQEKVKGKVRRKVTGTEGSSST----LVD--YTSTSSTGGSPVRKSEE---- 1250 Query: 992 TLVKENDPEANIDTIYDRFVHLDNLPEDGLQCVLCVGLQFGKVDHHVFISNRN--KAILQ 1049 + D + + + + + + P + + ++ + + K D F S K+ Sbjct: 1251 ----KTDTKRTVIKTMEEYNNDNTAPAEDV--IIMIQVPQSKWDKDDFESEEEDVKSTQP 1304 Query: 1050 LDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGLKNSPID 1109 + S S+ + P NI + PE + E +++K + + + I Sbjct: 1305 ISSVGKPASVIKNVSTKPSNI------------VKYPEKESEPSEKIQKFTKDVSHE-II 1351 Query: 1110 ESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELET 1169 + EV+++ +S S + + ++ ++ E +++ + E E + L Sbjct: 1352 QHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQ 1411 Query: 1170 QGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTALLPSDSV 1229 +E + ++ + S + FT N ++ +D + + S S Sbjct: 1412 SSKEARTSDKHDSTRASSNKDFTPNRDK--------KTDYDTREY-----------SSSK 1452 Query: 1230 FAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPT 1289 +E+N ++SPS +D SG +KN+ E +P T Sbjct: 1453 RRDEKNELTRRKDSPSRNKDSASG------------QKNKPREE--------RDLPKKGT 1492 Query: 1290 GDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAEKVEKMAAM 1349 GD K K N S + + ++TK + T+ +KN + + V + Sbjct: 1493 GDSK---KSNSSPSRDRKPHDHKATYDTKRPNEE----TKSVDKNPCKDREKHVLEARNN 1545 Query: 1350 KEKPAENTLFKAYP-------NKGVGQANKPDETSKTSILAVSDVSS--SKPSIKAVI-- 1398 KE L+ P + GQ +K K + S +SS ++ + +A Sbjct: 1546 KESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEP 1605 Query: 1399 ---VSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSK 1455 S ++ +V + E+ + K + +D+I + K S +++ +R+ + SS Sbjct: 1606 DYNESDSESNVSVKEEESSGNISKDL-KDKIVEKAKESLDTAAVVQVGISRN-QSHSSPS 1663 Query: 1456 FKPTQS-----SLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTL 1510 P++S S TR S S+ + + SK + K+ + + K+ L Sbjct: 1664 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVEL 1723 Query: 1511 AEQNTKNPKSTTGRSSKSKEE 1531 + K + +K KE+ Sbjct: 1724 EKSQKHKHKKKKSKKNKDKEK 1744 Score = 60.8 bits (146), Expect = 1e-08 Identities = 187/965 (19%), Positives = 342/965 (35%), Gaps = 157/965 (16%) Query: 466 PEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSS-SSHRFRRSRSPMHYMYRP------ 518 PE L S R+ N+K+N + + +P + + HR RR P Sbjct: 865 PEKL-SARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETS 923 Query: 519 -RSRSPRICHRFISRYRSRSRSRSPYRI-RNPFRGSPKCFRSVSPERMSRRSVRSSDRKK 576 +SR P + ++ S P R P R P S++ + +S + R D+ K Sbjct: 924 RKSREPT----GVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPK 979 Query: 577 ALEDVVQRSGHGTEFNKQKHL---------------EAADKGHSPAQKPKTSSGTKPSVK 621 A D +R G+ +K++++ E + + P +K K + + K Sbjct: 980 AKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTK 1039 Query: 622 PTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGSVLLIT 681 +S+++ D + G + SK+ ++ E K V ++ K++K+ S S L T Sbjct: 1040 SSSSSQKDEKITGTPRKAHSKSAKEH--QETKPVKEE------KVKKDYSKDVKSEKLTT 1091 Query: 682 ELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRK--EAYLEMEFKEAITAIMKYIETTPLTI 739 + EE +K + +++ RK E ++ +F+ + I K +E T + Sbjct: 1092 K-------EEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK-LEVTEIVK 1143 Query: 740 KGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADASKAVEIVTSTSAAKTGQAK 799 P +K + E +T E K+S S A Sbjct: 1144 PS-------PKRKMEPDTEKMDRTPEKDKISLS-------------------------AP 1171 Query: 800 ASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKNKDSNKPV 859 A K+N+ TGK S ++ + K + +S K + K G V+ K V Sbjct: 1172 AKKIKLNRETGKKIGSTEN-----ISNTKEPSEKLESTSSKVKQEKVKGKVRRK-----V 1221 Query: 860 TIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKETEEM---------CVMLVS 910 T E S T ++ +T + + + + + K EE V+++ Sbjct: 1222 TGTEGSS-STLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMI 1280 Query: 911 NLPNKGY-------------SVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMV 957 +P + S + + + KP +K++ S+ Y E + +E + Sbjct: 1281 QVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQ 1340 Query: 958 KFYTCFP---VLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLD 1014 KF + + S + E KD + + L KEN + T ++ +LD Sbjct: 1341 KFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRD--YSVLEKENPEKRKNSTQPEKESNLD 1398 Query: 1015 NLPEDGLQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPES--AQSMYSFLKQNPQNIGD 1072 L E G + +S +K D +S A S F + Sbjct: 1399 RLNEQG---------------NFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY 1443 Query: 1073 HMLTCSLSPKIDLPE--VQIEHDPELEKES-PGLKNSPIDESEVQTATDSPSVKPNELEE 1129 S S + D + + P K+S G KN P +E ++ S K N Sbjct: 1444 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPS 1503 Query: 1130 ESTPSIQTETLVQQEEPCEE--EAEKATCDSDFAVETLELETQGEEVKEEIPLVAS---A 1184 + + P EE +K C D LE E ++ + + Sbjct: 1504 RDRKPHDHKATYDTKRPNEETKSVDKNPC-KDREKHVLEARNNKESSGNKLLYILNPPET 1562 Query: 1185 SVSIEQFTENAEECALNQQMFNSDLEKKGAEII--NPKTALLPSDSVFAEERNLKGILEE 1242 V EQ T ++ + + S + +++ + A P + E N+ EE Sbjct: 1563 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1622 Query: 1243 S----PSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKK 1298 S + +D I + ++ A V+ + ++ S + P+G + Sbjct: 1623 SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1682 Query: 1299 NI-------SEKKGNMDEKEEKEFNTKETRMDLQIGTE-KAEKNEGRMDAEKVEKMAAMK 1350 + S+KK EK++ + + K + GTE + EK++ +K K K Sbjct: 1683 SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK 1742 Query: 1351 EKPAE 1355 EK E Sbjct: 1743 EKEKE 1747 Score = 54.7 bits (130), Expect = 9e-07 Identities = 147/735 (20%), Positives = 268/735 (36%), Gaps = 86/735 (11%) Query: 1285 PGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNT---------KETRMDLQIGTEKAEKNE 1335 P I E+T K + K + +K+EK T KE + + EK +K+ Sbjct: 1023 PPIKKAKEET--PKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1080 Query: 1336 GR-MDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSI 1394 + + +EK+ +KP E K NKG + K +E S + SK + Sbjct: 1081 SKDVKSEKLTTKEEKAKKPNEKN--KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEV 1138 Query: 1395 KAVIVSSPKAK-----ATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGL 1449 ++ SPK K + +T + S P +I ++ K + T S Sbjct: 1139 TEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK----IGSTENISNT 1194 Query: 1450 AESSSKFKPTQSSL----TRGGSGR-ISALQGKLSKLDYRDITKQSQETEARPSIMKRDD 1504 E S K + T S + +G R ++ +G S L T + + R S K D Sbjct: 1195 KEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDT 1254 Query: 1505 SNN--KTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLK 1562 KT+ E N N + P ++ D+F + +E ++ P + Sbjct: 1255 KRTVIKTMEEYNNDNTAPAEDVIIMI-QVPQSKWDKDDFESEEEDVKSTQPISS-----V 1308 Query: 1563 GKRKETLKNVPFSELNLKKKKGKTSTP-RGVEGELSFVTLDEIGEEEDAAAHLAQALVTV 1621 GK +KNV N+ K K S P ++ V+ + I E ++ + A + Sbjct: 1309 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1368 Query: 1622 DEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLV 1681 + D L E K NS ++P+ + L EQ K Sbjct: 1369 TKDRDYSVLEKENPEKRKNS----------------TQPEKESNLDRLNEQGNFKSLSQS 1412 Query: 1682 TVDEIGEVEELPLNESADITFATLN---TKGNEGDTVRDSIGFISSQVPEDPSTLVTVDE 1738 + +E ++ D T A+ N T + T D+ + SS+ ++ + L + Sbjct: 1413 S-------KEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD 1465 Query: 1739 IQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSK 1798 + D ++ EE + + K+ + + D + D K ++K Sbjct: 1466 SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETK 1525 Query: 1799 NDHPTDKKGNRKKRAVDTKKTKLES----LSQVGPVNENVMEEDLKTMIERHLTAKTPTK 1854 + K +R+K ++ + K S L + P V +E + I++ + P Sbjct: 1526 SVDKNPCK-DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDK--STVKPKP 1582 Query: 1855 RVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASD 1914 ++ L S+ T+ A E + +E D ES + E E ++D + Sbjct: 1583 QLSHSSRLSSDLTRETDEAAFEPDY--NESDSESNVSVKEEESSGNISKDLKD--KIVEK 1638 Query: 1915 VPEELD-FLVPKAGF----------FCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQ 1963 E LD V + G P S SG + +H S ++ + K+ Sbjct: 1639 AKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQT-RSHSSSASSAESQDSKKKKK 1697 Query: 1964 RKEKEQNEAEERSSR 1978 +KEK++++ ++ + Sbjct: 1698 KKEKKKHKKHKKHKK 1712 Score = 43.9 bits (102), Expect = 0.002 Identities = 97/416 (23%), Positives = 152/416 (36%), Gaps = 97/416 (23%) Query: 1265 VEKNETVSE-ILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMD 1323 VE+N+T S +LPS T V P D +++ K++SEK D++E + K Sbjct: 932 VEENKTDSLFVLPSRDDATPVRDEPM-DAESITFKSVSEK----DKRERDKPKAK----- 981 Query: 1324 LQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILA 1383 G + KN+G ++K + KPA+ G K D + S Sbjct: 982 ---GDKTKRKNDGSAVSKKENIV-----KPAK------------GPQEKVDGERERS--- 1018 Query: 1384 VSDVSSSKPSIKAVIVSSPKAKATVSKTENQ----------KSFPKSVPRDQ----INAE 1429 S+P IK +PK T S + +Q K+ KS Q + E Sbjct: 1019 ----PRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEE 1074 Query: 1430 K------------KLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGK 1477 K KL+ KE KP L K K + + +G + K Sbjct: 1075 KVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRK--RKTEEKGVDKDFESSSMK 1132 Query: 1478 LSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPK----STTGRSSKSKEEPL 1533 +SKL+ +I K S + + P K D + K + K TG+ S E Sbjct: 1133 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTE--- 1189 Query: 1534 FPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNL-------------- 1579 N+ E +E + S+ KQ +KGK + + S L Sbjct: 1190 ---NISNTKEPSEKLESTS-SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1245 Query: 1580 KKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDE-VIDEEELNMEE 1634 +K + KT T R V T++E + A A ++ V + D+++ EE Sbjct: 1246 RKSEEKTDTKRTV-----IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE 1296 Score = 39.7 bits (91), Expect = 0.030 Identities = 107/614 (17%), Positives = 215/614 (35%), Gaps = 102/614 (16%) Query: 94 QKKGKPHGSRWDDEPHISASVAVKQSSVTQVTEQSPKVQSRYTKESASSILASFGLSNED 153 +K+ + + D+ S+S+ + + VT++ + SPK + D Sbjct: 1111 EKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK-----------------MEPD 1153 Query: 154 LEELSRYPDEQLTPENMPLILRDIRM-RKMGRRLPNLPSQSRNKE--------------- 197 E++ R P++ + P + I++ R+ G+++ + + S KE Sbjct: 1154 TEKMDRTPEKDKISLSAP--AKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211 Query: 198 ---------TLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVENEFQSQQNI 248 G+E SS ++DY S G + P + E + +++ + Sbjct: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGS-------------PVRKSEEKTDTKRTV 1258 Query: 249 SASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISGGQSVLEPI 308 ++ N ++ P EDV + P + F S E K + +PI Sbjct: 1259 IKTMEEYN--NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKST-----------QPI 1305 Query: 309 KSVNQ--SINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSSNVHVGS 366 SV + S+ + VS S + P +P SE I ++ + HE + + S Sbjct: 1306 SSVGKPASVIKNVSTKPSNIVKYPEKESEP--SEKIQKFTKD--VSHEIIQHEVKSSKNS 1361 Query: 367 RGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAASPRIFPH 426 S+K D + + K + + + +K L + ++ + S Sbjct: 1362 ASSEKGKTKDRDYSV-----LEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEA 1416 Query: 427 LCS--LCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEIL-----PSRRNEGNRK 479 S + S KD+ +++ T ++ + D E+ PSR + Sbjct: 1417 RTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASG 1476 Query: 480 ENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRS 539 + PR P S+ R R P + ++ P + + + + R Sbjct: 1477 QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDRE 1536 Query: 540 RSPYRIRN--PFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHL 597 + RN G+ + PE + + K+ + H + + Sbjct: 1537 KHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTR 1596 Query: 598 EAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSD 657 E + P ++ S + SVK +S N+ SK+L+D + + K+ D Sbjct: 1597 ETDEAAFEPDYN-ESDSESNVSVK---EEESSGNI--------SKDLKDKIVEKAKESLD 1644 Query: 658 KAVSLQRKLRKEQS 671 A +Q + + QS Sbjct: 1645 TAAVVQVGISRNQS 1658 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 61.6 bits (148), Expect = 7e-09 Identities = 226/1161 (19%), Positives = 411/1161 (35%), Gaps = 191/1161 (16%) Query: 471 SRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFI 530 S R+ + RS+S SP RR R RSRS H +R RSRSP Sbjct: 709 STRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPP-----Y 763 Query: 531 SRYRSRSRSRSPYRIRNP-FRGSPK---------CFRSVSPE-RMSRRSVRSSDRKKALE 579 RY SRSRS +R ++P R P+ +R V P M RS D + E Sbjct: 764 RRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFE 823 Query: 580 DVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKP-----------SVKPTSATKS 628 R E ++ E KG++ +P+ S+ + P + + Sbjct: 824 KERYRE---WERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRR 880 Query: 629 DSNLGGHSIRCKS--------------KNLEDDTLSECKQ----VSDKAVSLQRKLRKEQ 670 + +GG S R ++ N +D+T S+ K+ D + +K RK + Sbjct: 881 EDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRR 940 Query: 671 SLHYGSVLLITELPEDGCTEEDVRKLFQPFG----KVNDVLIVPYRKEAY-LEMEFKEAI 725 L EL E RK +P G K + + ++P R +A + E +A Sbjct: 941 KGEESEGFLNPELLETS------RKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAE 994 Query: 726 TAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADASKAVE 785 + K + + K K+K V KK K K D + ++ Sbjct: 995 SITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPR 1054 Query: 786 IVTSTSAAKTGQAKASVAKVNKSTGK------------SASSVKSVVTVAVKGNKASIKT 833 AK K K + S+ K S S+ + T VK K Sbjct: 1055 SEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1114 Query: 834 AKSGGKKSLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATE 893 +K + L K+ K + NKP+ + + E ++ ++ + LE TE Sbjct: 1115 SKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTE 1174 Query: 894 ------NEPLNKETEEM----------------CVMLVSNLPNKGYSVEEVYDLAKPFGG 931 + +TE+M + L K S E + + +P Sbjct: 1175 IVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEK 1234 Query: 932 LKDILILSSHKKAYIEINRKAAESMVKFYTCFPVLMDGNQLSISMAPENMNIKDEEAIFI 991 L+ +K ++ RK + T L+D S S + K EE Sbjct: 1235 LESTSSKVKQEKVKGKVRRKVTGTEGSSST----LVD--YTSTSSTGGSPVRKSEE---- 1284 Query: 992 TLVKENDPEANIDTIYDRFVHLDNLPEDGLQCVLCVGLQFGKVDHHVFISNRN--KAILQ 1049 + D + + + + + + P + + ++ + + K D F S K+ Sbjct: 1285 ----KTDTKRTVIKTMEEYNNDNTAPAEDV--IIMIQVPQSKWDKDDFESEEEDVKSTQP 1338 Query: 1050 LDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGLKNSPID 1109 + S S+ + P NI + PE + E +++K + + + I Sbjct: 1339 ISSVGKPASVIKNVSTKPSNI------------VKYPEKESEPSEKIQKFTKDVSHE-II 1385 Query: 1110 ESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELET 1169 + EV+++ +S S + + ++ ++ E +++ + E E + L Sbjct: 1386 QHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQ 1445 Query: 1170 QGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTALLPSDSV 1229 +E + ++ + S + FT N ++ +D + + S S Sbjct: 1446 SSKEARTSDKHDSTRASSNKDFTPNRDK--------KTDYDTREY-----------SSSK 1486 Query: 1230 FAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPT 1289 +E+N ++SPS +D SG +KN+ E +P T Sbjct: 1487 RRDEKNELTRRKDSPSRNKDSASG------------QKNKPREE--------RDLPKKGT 1526 Query: 1290 GDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAEKVEKMAAM 1349 GD K K N S + + ++TK + T+ +KN + + V + Sbjct: 1527 GDSK---KSNSSPSRDRKPHDHKATYDTKRPNEE----TKSVDKNPCKDREKHVLEARNN 1579 Query: 1350 KEKPAENTLFKAYP-------NKGVGQANKPDETSKTSILAVSDVSS--SKPSIKAVI-- 1398 KE L+ P + GQ +K K + S +SS ++ + +A Sbjct: 1580 KESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEP 1639 Query: 1399 ---VSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSK 1455 S ++ +V + E+ + K + +D+I + K S +++ +R+ + SS Sbjct: 1640 DYNESDSESNVSVKEEESSGNISKDL-KDKIVEKAKESLDTAAVVQVGISRN-QSHSSPS 1697 Query: 1456 FKPTQS-----SLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTL 1510 P++S S TR S S+ + + SK + K+ + + K+ L Sbjct: 1698 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVEL 1757 Query: 1511 AEQNTKNPKSTTGRSSKSKEE 1531 + K + +K KE+ Sbjct: 1758 EKSQKHKHKKKKSKKNKDKEK 1778 Score = 60.8 bits (146), Expect = 1e-08 Identities = 187/965 (19%), Positives = 342/965 (35%), Gaps = 157/965 (16%) Query: 466 PEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSS-SSHRFRRSRSPMHYMYRP------ 518 PE L S R+ N+K+N + + +P + + HR RR P Sbjct: 899 PEKL-SARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETS 957 Query: 519 -RSRSPRICHRFISRYRSRSRSRSPYRI-RNPFRGSPKCFRSVSPERMSRRSVRSSDRKK 576 +SR P + ++ S P R P R P S++ + +S + R D+ K Sbjct: 958 RKSREPT----GVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPK 1013 Query: 577 ALEDVVQRSGHGTEFNKQKHL---------------EAADKGHSPAQKPKTSSGTKPSVK 621 A D +R G+ +K++++ E + + P +K K + + K Sbjct: 1014 AKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTK 1073 Query: 622 PTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGSVLLIT 681 +S+++ D + G + SK+ ++ E K V ++ K++K+ S S L T Sbjct: 1074 SSSSSQKDEKITGTPRKAHSKSAKEH--QETKPVKEE------KVKKDYSKDVKSEKLTT 1125 Query: 682 ELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRK--EAYLEMEFKEAITAIMKYIETTPLTI 739 + EE +K + +++ RK E ++ +F+ + I K +E T + Sbjct: 1126 K-------EEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK-LEVTEIVK 1177 Query: 740 KGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADASKAVEIVTSTSAAKTGQAK 799 P +K + E +T E K+S S A Sbjct: 1178 PS-------PKRKMEPDTEKMDRTPEKDKISLS-------------------------AP 1205 Query: 800 ASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKNKDSNKPV 859 A K+N+ TGK S ++ + K + +S K + K G V+ K V Sbjct: 1206 AKKIKLNRETGKKIGSTEN-----ISNTKEPSEKLESTSSKVKQEKVKGKVRRK-----V 1255 Query: 860 TIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKETEEM---------CVMLVS 910 T E S T ++ +T + + + + + K EE V+++ Sbjct: 1256 TGTEGSS-STLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMI 1314 Query: 911 NLPNKGY-------------SVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMV 957 +P + S + + + KP +K++ S+ Y E + +E + Sbjct: 1315 QVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQ 1374 Query: 958 KFYTCFP---VLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYDRFVHLD 1014 KF + + S + E KD + + L KEN + T ++ +LD Sbjct: 1375 KFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRD--YSVLEKENPEKRKNSTQPEKESNLD 1432 Query: 1015 NLPEDGLQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPES--AQSMYSFLKQNPQNIGD 1072 L E G + +S +K D +S A S F + Sbjct: 1433 RLNEQG---------------NFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY 1477 Query: 1073 HMLTCSLSPKIDLPE--VQIEHDPELEKES-PGLKNSPIDESEVQTATDSPSVKPNELEE 1129 S S + D + + P K+S G KN P +E ++ S K N Sbjct: 1478 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPS 1537 Query: 1130 ESTPSIQTETLVQQEEPCEE--EAEKATCDSDFAVETLELETQGEEVKEEIPLVAS---A 1184 + + P EE +K C D LE E ++ + + Sbjct: 1538 RDRKPHDHKATYDTKRPNEETKSVDKNPC-KDREKHVLEARNNKESSGNKLLYILNPPET 1596 Query: 1185 SVSIEQFTENAEECALNQQMFNSDLEKKGAEII--NPKTALLPSDSVFAEERNLKGILEE 1242 V EQ T ++ + + S + +++ + A P + E N+ EE Sbjct: 1597 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1656 Query: 1243 S----PSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKK 1298 S + +D I + ++ A V+ + ++ S + P+G + Sbjct: 1657 SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1716 Query: 1299 NI-------SEKKGNMDEKEEKEFNTKETRMDLQIGTE-KAEKNEGRMDAEKVEKMAAMK 1350 + S+KK EK++ + + K + GTE + EK++ +K K K Sbjct: 1717 SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK 1776 Query: 1351 EKPAE 1355 EK E Sbjct: 1777 EKEKE 1781 Score = 54.7 bits (130), Expect = 9e-07 Identities = 147/735 (20%), Positives = 268/735 (36%), Gaps = 86/735 (11%) Query: 1285 PGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNT---------KETRMDLQIGTEKAEKNE 1335 P I E+T K + K + +K+EK T KE + + EK +K+ Sbjct: 1057 PPIKKAKEET--PKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY 1114 Query: 1336 GR-MDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSI 1394 + + +EK+ +KP E K NKG + K +E S + SK + Sbjct: 1115 SKDVKSEKLTTKEEKAKKPNEKN--KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEV 1172 Query: 1395 KAVIVSSPKAK-----ATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGL 1449 ++ SPK K + +T + S P +I ++ K + T S Sbjct: 1173 TEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK----IGSTENISNT 1228 Query: 1450 AESSSKFKPTQSSL----TRGGSGR-ISALQGKLSKLDYRDITKQSQETEARPSIMKRDD 1504 E S K + T S + +G R ++ +G S L T + + R S K D Sbjct: 1229 KEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDT 1288 Query: 1505 SNN--KTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLK 1562 KT+ E N N + P ++ D+F + +E ++ P + Sbjct: 1289 KRTVIKTMEEYNNDNTAPAEDVIIMI-QVPQSKWDKDDFESEEEDVKSTQPISS-----V 1342 Query: 1563 GKRKETLKNVPFSELNLKKKKGKTSTP-RGVEGELSFVTLDEIGEEEDAAAHLAQALVTV 1621 GK +KNV N+ K K S P ++ V+ + I E ++ + A + Sbjct: 1343 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1402 Query: 1622 DEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLV 1681 + D L E K NS ++P+ + L EQ K Sbjct: 1403 TKDRDYSVLEKENPEKRKNS----------------TQPEKESNLDRLNEQGNFKSLSQS 1446 Query: 1682 TVDEIGEVEELPLNESADITFATLN---TKGNEGDTVRDSIGFISSQVPEDPSTLVTVDE 1738 + +E ++ D T A+ N T + T D+ + SS+ ++ + L + Sbjct: 1447 S-------KEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD 1499 Query: 1739 IQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSK 1798 + D ++ EE + + K+ + + D + D K ++K Sbjct: 1500 SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETK 1559 Query: 1799 NDHPTDKKGNRKKRAVDTKKTKLES----LSQVGPVNENVMEEDLKTMIERHLTAKTPTK 1854 + K +R+K ++ + K S L + P V +E + I++ + P Sbjct: 1560 SVDKNPCK-DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDK--STVKPKP 1616 Query: 1855 RVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASD 1914 ++ L S+ T+ A E + +E D ES + E E ++D + Sbjct: 1617 QLSHSSRLSSDLTRETDEAAFEPDY--NESDSESNVSVKEEESSGNISKDLKD--KIVEK 1672 Query: 1915 VPEELD-FLVPKAGF----------FCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQ 1963 E LD V + G P S SG + +H S ++ + K+ Sbjct: 1673 AKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQT-RSHSSSASSAESQDSKKKKK 1731 Query: 1964 RKEKEQNEAEERSSR 1978 +KEK++++ ++ + Sbjct: 1732 KKEKKKHKKHKKHKK 1746 Score = 43.9 bits (102), Expect = 0.002 Identities = 97/416 (23%), Positives = 152/416 (36%), Gaps = 97/416 (23%) Query: 1265 VEKNETVSE-ILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMD 1323 VE+N+T S +LPS T V P D +++ K++SEK D++E + K Sbjct: 966 VEENKTDSLFVLPSRDDATPVRDEPM-DAESITFKSVSEK----DKRERDKPKAK----- 1015 Query: 1324 LQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILA 1383 G + KN+G ++K + KPA+ G K D + S Sbjct: 1016 ---GDKTKRKNDGSAVSKKENIV-----KPAK------------GPQEKVDGERERS--- 1052 Query: 1384 VSDVSSSKPSIKAVIVSSPKAKATVSKTENQ----------KSFPKSVPRDQ----INAE 1429 S+P IK +PK T S + +Q K+ KS Q + E Sbjct: 1053 ----PRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEE 1108 Query: 1430 K------------KLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGK 1477 K KL+ KE KP L K K + + +G + K Sbjct: 1109 KVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRK--RKTEEKGVDKDFESSSMK 1166 Query: 1478 LSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPK----STTGRSSKSKEEPL 1533 +SKL+ +I K S + + P K D + K + K TG+ S E Sbjct: 1167 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTE--- 1223 Query: 1534 FPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNL-------------- 1579 N+ E +E + S+ KQ +KGK + + S L Sbjct: 1224 ---NISNTKEPSEKLESTS-SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1279 Query: 1580 KKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDE-VIDEEELNMEE 1634 +K + KT T R V T++E + A A ++ V + D+++ EE Sbjct: 1280 RKSEEKTDTKRTV-----IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEE 1330 Score = 39.7 bits (91), Expect = 0.030 Identities = 107/614 (17%), Positives = 215/614 (35%), Gaps = 102/614 (16%) Query: 94 QKKGKPHGSRWDDEPHISASVAVKQSSVTQVTEQSPKVQSRYTKESASSILASFGLSNED 153 +K+ + + D+ S+S+ + + VT++ + SPK + D Sbjct: 1145 EKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK-----------------MEPD 1187 Query: 154 LEELSRYPDEQLTPENMPLILRDIRM-RKMGRRLPNLPSQSRNKE--------------- 197 E++ R P++ + P + I++ R+ G+++ + + S KE Sbjct: 1188 TEKMDRTPEKDKISLSAP--AKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1245 Query: 198 ---------TLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVENEFQSQQNI 248 G+E SS ++DY S G + P + E + +++ + Sbjct: 1246 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGS-------------PVRKSEEKTDTKRTV 1292 Query: 249 SASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISGGQSVLEPI 308 ++ N ++ P EDV + P + F S E K + +PI Sbjct: 1293 IKTMEEYN--NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKST-----------QPI 1339 Query: 309 KSVNQ--SINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSSNVHVGS 366 SV + S+ + VS S + P +P SE I ++ + HE + + S Sbjct: 1340 SSVGKPASVIKNVSTKPSNIVKYPEKESEP--SEKIQKFTKD--VSHEIIQHEVKSSKNS 1395 Query: 367 RGSKKNYQSQADIPIRSPFGIVKASWLPKFSHADAQKMKRLPTPSMMNDYYAASPRIFPH 426 S+K D + + K + + + +K L + ++ + S Sbjct: 1396 ASSEKGKTKDRDYSV-----LEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEA 1450 Query: 427 LCS--LCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEIL-----PSRRNEGNRK 479 S + S KD+ +++ T ++ + D E+ PSR + Sbjct: 1451 RTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASG 1510 Query: 480 ENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRS 539 + PR P S+ R R P + ++ P + + + + R Sbjct: 1511 QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDRE 1570 Query: 540 RSPYRIRN--PFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHL 597 + RN G+ + PE + + K+ + H + + Sbjct: 1571 KHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTR 1630 Query: 598 EAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSD 657 E + P ++ S + SVK +S N+ SK+L+D + + K+ D Sbjct: 1631 ETDEAAFEPDYN-ESDSESNVSVK---EEESSGNI--------SKDLKDKIVEKAKESLD 1678 Query: 658 KAVSLQRKLRKEQS 671 A +Q + + QS Sbjct: 1679 TAAVVQVGISRNQS 1692 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 61.6 bits (148), Expect = 7e-09 Identities = 61/202 (30%), Positives = 86/202 (42%), Gaps = 26/202 (12%) Query: 470 PSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRF 529 P+RR +R R RS +P+ RRSR S R RSRSP R RSR+P Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP------ 652 Query: 530 ISRYRSRSRSRSP-----YRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQR 584 R RSRSR+P R R P R S + RS +P R R R+ R ++ + R Sbjct: 653 --ARRGRSRSRTPARRGRSRSRTPARRSGRS-RSRTPARRGRSRSRTPRRGRSRSRSLVR 709 Query: 585 SGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNL 644 G Q+ +G S SS + + TS +S SN + + + Sbjct: 710 RGRSHSRTPQR------RGRS------GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757 Query: 645 EDDTLSECKQVSDKAVSLQRKL 666 +LS + + +SL+R L Sbjct: 758 RSRSLSSPRSKAKSRLSLRRSL 779 Score = 52.0 bits (123), Expect = 6e-06 Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 16/157 (10%) Query: 478 RKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRS 537 +K+ + RRS S SPRR R+ SS + RS S + + RSP + S+ + R Sbjct: 190 KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK---KRKHRSPTPKSKRKSKDKKRK 246 Query: 538 RSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHL 597 RSRS P S + RS S + S SSD ++ H T + Sbjct: 247 RSRS----TTPAPKSRRAHRSTSAD-----SASSSDTSRSRSRSAAAKTHTTALAGRSPS 297 Query: 598 EAADK---GHSPAQKPKTSSGTKPSVKPTSATKSDSN 631 A+ + G +P +P T+S +PS P +ATK S+ Sbjct: 298 PASGRRGEGDAPFSEPGTTSTQRPS-SPETATKQPSS 333 Score = 50.4 bits (119), Expect = 2e-05 Identities = 58/195 (29%), Positives = 76/195 (38%), Gaps = 29/195 (14%) Query: 458 RQQYPDWNPEILPSRRNEGNRK--ENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYM 515 R + P W RR+ ++ + +P+RR S SP+R S S + RR RS Sbjct: 507 RSRSPQW-------RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARR 559 Query: 516 YRPRSRSPRICHRFISR-------------YRSRSRSRSPYRIRNPFRGSPKCFRSVSPE 562 R SRSP R SR R RSRSR+P R R+ R + RS S Sbjct: 560 GRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619 Query: 563 RMSRRS-------VRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSG 615 RRS RS R A RS + + A +G S ++ P SG Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679 Query: 616 TKPSVKPTSATKSDS 630 S P +S S Sbjct: 680 RSRSRTPARRGRSRS 694 Score = 49.7 bits (117), Expect = 3e-05 Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 17/165 (10%) Query: 478 RKENETPRRRSHSPSPRRS-RRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISR-YRS 535 R + TP +R HS S RRS S+ R+ RSRSP R RSRSP+ SR + Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR---RGRSRSPQRPGWSRSRNTQR 550 Query: 536 RSRSRSPYRIRNPFRGSPKC---FRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFN 592 R RSRS R R+ R SP RS +P R R R+ R+++ R Sbjct: 551 RGRSRSARRGRSHSR-SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR-------R 602 Query: 593 KQKHLEAADKGHSPAQKP-KTSSGTKPSVKPTSATKSDSNLGGHS 636 + + A +G S ++ P + S T+ V+ S ++S + G S Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647 Score = 49.7 bits (117), Expect = 3e-05 Identities = 46/108 (42%), Positives = 58/108 (53%), Gaps = 17/108 (15%) Query: 471 SRRNEGNRKENETPRRRSHS---PSP---RRSRRSSSSHRFRRSRSPMHYMYRPRSR-SP 523 SRR G + T R+RS S P+P RSR S ++HR RSR+P+ R RSR SP Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894 Query: 524 RICHRFISRYRSRSRSRSPYRIRNPFRGSP---KCFRSVSPERMSRRS 568 +SR RSRSR+ S R R+ R SP + RS +P RRS Sbjct: 1895 ------VSRRRSRSRT-SVTRRRSRSRASPVSRRRSRSRTPPVTRRRS 1935 Score = 48.1 bits (113), Expect = 8e-05 Identities = 52/137 (37%), Positives = 63/137 (45%), Gaps = 18/137 (13%) Query: 471 SRRNEGNRKENETPRRRSHSPSP---RRSRRSSSSHRFRRSRSPMHYMYRPRSRS---PR 524 +RR +R T RR SP RRSR +S RRSRS + R RSRS P Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025 Query: 525 ICHRFISRY----RSRSRSRSPYRIRNPFRG-SPKCFRSV-----SPERMSRRSVR--SS 572 I R SR R RSRSRSP IR R +P+ R SP + RRS SS Sbjct: 2026 IRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSS 2085 Query: 573 DRKKALEDVVQRSGHGT 589 DR ++ R+ G+ Sbjct: 2086 DRSRSATPPATRNHSGS 2102 Score = 45.8 bits (107), Expect = 4e-04 Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 23/175 (13%) Query: 465 NPEIL-PSRRNEGNRKENETPRRRSHSP----------SPRRSRRSSSSHRFRRSRSPMH 513 +PE+ +R + +R + +P RS +P SP + +S SS R R + SP Sbjct: 1694 SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753 Query: 514 YMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSD 573 R RSP R + R RSRSR R R + + RS S + SRR RS Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSR-------REKTRTTRRRDRSGSSQSTSRRRQRSRS 1806 Query: 574 RKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKS 628 R + V +R G+ ++ + + + +++ + S T P+ + S +++ Sbjct: 1807 RSR----VTRRRRGGSGYHSRSPAR-QESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856 Score = 45.1 bits (105), Expect = 7e-04 Identities = 57/220 (25%), Positives = 82/220 (37%), Gaps = 36/220 (16%) Query: 444 HQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKENETPRRRS---HSPSPRRSRRSS 500 H ++S H +++ P I + NE ++ TP+RRS SP P R+ Sbjct: 835 HSSSSPH----PKVKSGTPPRQGSITSPQANE----QSVTPQRRSCFESSPDPELKSRTP 886 Query: 501 SSH--------RFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGS 552 S H R + S P R S P++ R RS S S SP R R + Sbjct: 887 SRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTT 946 Query: 553 PKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKT 612 P+ RSVSP S+ + L SG + K K + HS + P Sbjct: 947 PRRSRSVSP---------CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP-- 995 Query: 613 SSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSEC 652 P VK + T +L G C + +D + C Sbjct: 996 ----YPKVK--AQTPPGPSLSGSKSPCPQEKSKDSLVQSC 1029 Score = 44.7 bits (104), Expect = 0.001 Identities = 49/188 (26%), Positives = 76/188 (40%), Gaps = 22/188 (11%) Query: 462 PDWNPEILPSRRNEGNRKENET-----PRRRSHSPSPRRSRRSSSSHRFR--------RS 508 P+ P+ +RR + E +T PRRRS SP +R++ S R R RS Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718 Query: 509 RSPMHYMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRS 568 R+P + P SP + S R RS S SP RG RS SP+ + Sbjct: 1719 RTPPRHRRSPSVSSPEPAEKSRSSRRRRSAS-SPRTKTTSRRG-----RSPSPKPRGLQR 1772 Query: 569 VRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSG---TKPSVKPTSA 625 RS R++ +R G+ + + + + ++ + SG P+ + +S Sbjct: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832 Query: 626 TKSDSNLG 633 T S G Sbjct: 1833 TSSRRRRG 1840 Score = 42.0 bits (97), Expect = 0.006 Identities = 62/210 (29%), Positives = 84/210 (40%), Gaps = 38/210 (18%) Query: 469 LPSRRNEGNRKENETPRRRSHSPSP-----RRSRRSSSSHRFRRSRSPMHYMYRPRSRSP 523 L SRR +R + RRRS S + RSR S S R RSR+P R RSR+P Sbjct: 1882 LISRRRSRSRT-SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940 Query: 524 RICHRFISR----YRSRSRSRSP--------------YRIRNPFRGSPKCFR----SVSP 561 R SR R RSRSR+P R R+ R SP R SP Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000 Query: 562 ERMSRRSVRSS------DRKKALEDVVQRSGHGTEFNKQKHLEA----ADKGHSPAQKPK 611 R R+S R + + +RS T +K + A + S ++ P+ Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060 Query: 612 TSSGTKPSVKPTSATKSDSNLGGHSIRCKS 641 T+ G + + A + S G S R +S Sbjct: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090 Score = 41.6 bits (96), Expect = 0.008 Identities = 54/196 (27%), Positives = 78/196 (39%), Gaps = 33/196 (16%) Query: 458 RQQYPDWNPEILPSRRNEGN-----------RKENETPRRRSHSPSPRRSRRSSSSH--- 503 R + P +PE LP + + R + +P +P+P R SSS Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460 Query: 504 -----RFRRSRSPMHYMYRP--RSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCF 556 R +R +S H R RSRSP R RSRSR+P + + SP+ Sbjct: 461 NRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR------GRSRSRTPTKRGHSRSRSPQWR 514 Query: 557 RSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQK--HLEAADKGHSPAQKPKTSS 614 RS S +R R S +++ QR G N Q+ +A +G S ++ P T Sbjct: 515 RSRSAQRWGR---SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT-R 570 Query: 615 GTKPSVKPTSATKSDS 630 G S P +S S Sbjct: 571 GRSRSRTPARRGRSRS 586 Score = 37.7 bits (86), Expect = 0.11 Identities = 42/152 (27%), Positives = 60/152 (39%), Gaps = 9/152 (5%) Query: 471 SRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFI 530 S + + +R E+E+ +R+ SP+P+ R+S R +RSRS R+ Sbjct: 212 SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR-KRSRSTTPAPKSRRAHRSTSADSAS 270 Query: 531 SRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTE 590 S SRSRSRS + + RS SP RR + + QR Sbjct: 271 SSDTSRSRSRSAAAKTHT---TALAGRSPSP-ASGRRGEGDAPFSEPGTTSTQRPSSPET 326 Query: 591 FNKQKHLEAADKGHSPAQKPKTSSGTKPSVKP 622 KQ DK +K S T+PS P Sbjct: 327 ATKQPSSPYEDKDKDKKEK----SATRPSPSP 354 Score = 37.4 bits (85), Expect = 0.15 Identities = 48/177 (27%), Positives = 63/177 (35%), Gaps = 42/177 (23%) Query: 466 PEILPSRRNEGNRKENETPRRRS---------HSPSPRRSRRSSSSHRFRRSRSPMHYMY 516 P LP R G+ + P H P R +RR S S +++S Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688 Query: 517 RPRSRSPRICHRFISRYRSRSRSRSP-YRIRNP--FRGSPKCFRSVSPERMSRRSVRSSD 573 R SP + + RSRS S SP R R P R SP SVS + +S RSS Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP----SVSSPEPAEKS-RSSR 1743 Query: 574 RKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDS 630 R+++ SP K + G PS KP +S S Sbjct: 1744 RRRS-------------------------ASSPRTKTTSRRGRSPSPKPRGLQRSRS 1775 Score = 36.2 bits (82), Expect = 0.33 Identities = 54/216 (25%), Positives = 82/216 (37%), Gaps = 26/216 (12%) Query: 471 SRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFI 530 SR ++ + N +P + S RRSR SS +SR + S P+ + Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP 793 Query: 531 SRYRSRS-------RSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQ 583 R RSRS +SR+P R P +S +P R S S SS K Sbjct: 794 PR-RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS--SSPHPKVKSGTPP 850 Query: 584 RSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHS---IRCK 640 R G T +A ++ +P ++ S P +K S T S + G S ++ Sbjct: 851 RQGSITS------PQANEQSVTPQRRSCFESSPDPELK--SRTPSRHSCSGSSPPRVKSS 902 Query: 641 SKNLEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGS 676 + + + S Q KA+ + Q H GS Sbjct: 903 TPPRQSPSRSSSPQPKVKAI-----ISPRQRSHSGS 933 Score = 36.2 bits (82), Expect = 0.33 Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 14/217 (6%) Query: 462 PDWNPEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHR-FRRSRSPMHYMYRPRS 520 P+ N + L +R + + + + +P +RSR SS + S SP S Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS 1562 Query: 521 RSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRS-VSPE-----RMSRRSVRSSDR 574 + R + R RSRS S + + R SP+ RS SPE R + R+ SD Sbjct: 1563 PDSKAKTR--TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS 1620 Query: 575 KKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGG 634 + R+ ++ ++ KG P+ + +S+ + P P S T + Sbjct: 1621 SPEPKAPAPRA-----LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675 Query: 635 HSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLRKEQS 671 + KS+ S + L R+ R S Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712 Score = 34.3 bits (77), Expect = 1.2 Identities = 43/182 (23%), Positives = 72/182 (39%), Gaps = 21/182 (11%) Query: 479 KENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSR-SPRICHRFISRYRSRS 537 K + +P+ RS S S S+ + + +RSRS +SR SPR RS Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR-----------RS 1596 Query: 538 RSRSPYRIRNPFRGSPKCF---------RSVSPERMSRRSVRSSDRKKALEDVVQRSGHG 588 RS S +++ R +P+ ++ +P + RRS S K S Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656 Query: 589 TEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDT 648 + A +G + +PKT S T P + + ++ + S R +S + +T Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716 Query: 649 LS 650 S Sbjct: 1717 RS 1718 Score = 33.9 bits (76), Expect = 1.6 Identities = 51/181 (28%), Positives = 74/181 (40%), Gaps = 26/181 (14%) Query: 470 PSRRNEGNRKENETPRRRSHSPSP---------------RRSRRSSSSHRFRRSRSPMHY 514 P+ + + RRS S +P RR RS +S RRSRS Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917 Query: 515 MYRPRSRS---PRICHRFISR---YRSRSRSRSPYRIRNPFRG-SPKCFRSVSPERMSRR 567 + R RSRS P R SR R RSRSR+P R R +P R S R S Sbjct: 1918 VSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI 1977 Query: 568 SVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATK 627 + R S R + +RS T ++ + SP + ++ S T P+++ S ++ Sbjct: 1978 TRRRS-RSRTSPVTRRRSRSRTSPVTRRRSRSRT---SPVTRRRSRSRTPPAIRRRSRSR 2033 Query: 628 S 628 + Sbjct: 2034 T 2034 Score = 33.1 bits (74), Expect = 2.8 Identities = 56/249 (22%), Positives = 96/249 (38%), Gaps = 30/249 (12%) Query: 1365 KGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSSPK---AKATVSKTENQKSFPKSV 1421 KG Q + PD S TS V S PS+++ +SPK ++++ TE P Sbjct: 1058 KGQSQTS-PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQ 1116 Query: 1422 PRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQG--KLS 1479 R + +A L + + P +R +S S PT S + G R+ + K++ Sbjct: 1117 DRGEFSASPMLKSG----MSPEQSR---FQSDSSSYPTVDSNSLLGQSRLETAESKEKMA 1169 Query: 1480 KLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNT----KNPKSTTGRSSKSKEE-PLF 1534 D T + + S D +L ++T +S G S ++KE+ Sbjct: 1170 LPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSAL 1229 Query: 1535 PFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEG 1594 P + + +E++E V S+ + LK + S S+P E Sbjct: 1230 PTSSQD----EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE--------SSPEVEER 1277 Query: 1595 ELSFVTLDE 1603 +TLD+ Sbjct: 1278 PAVSLTLDQ 1286 Score = 32.3 bits (72), Expect = 4.7 Identities = 43/136 (31%), Positives = 53/136 (38%), Gaps = 30/136 (22%) Query: 466 PEILPSRR--------NEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYR 517 PE P++R + + + + S S S S SSSS S SP Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655 Query: 518 P-----------------RSRSPRICHRFISRYR-SRSRSRSPYRIRNPF-RGSPKCFRS 558 P RSRSPR + I R SRS S SP R P + SP+ +S Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPR---KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712 Query: 559 VSPERMSRRSVRSSDR 574 S ER SRR R R Sbjct: 2713 SSSERGSRRGQRGDSR 2728 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 61.2 bits (147), Expect = 9e-09 Identities = 104/437 (23%), Positives = 183/437 (41%), Gaps = 69/437 (15%) Query: 468 ILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICH 527 I PSRR+ + + TP RRS +PS RRSR S RRSR+P RSR+P Sbjct: 1951 ISPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPS-----RRSRTPSR-----RSRTPSRRR 1999 Query: 528 RFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGH 587 R S R RS S SP R+R R R S + R+ RSS+R ++ + + Sbjct: 2000 RSRSVVRRRSFSISPVRLR---RSRTPLRRRFSRSPIRRKRSRSSERGRSPKRL------ 2050 Query: 588 GTEFNKQKHLEAADKGHSPAQKPKTS----SGTKPSVKPTSATKSDSNLGGHSIRCKSKN 643 T+ +K + LE A K ++ A K KP+ PT K GG +I Sbjct: 2051 -TDLDKAQLLEIA-KANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATI------ 2102 Query: 644 LEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQP---F 700 ++ +CKQ++ +++ + + E E+ KL +P F Sbjct: 2103 --EELTEKCKQIAQS--------KEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIF 2152 Query: 701 GKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVK 760 +N P ++ + + + +++ ++ + ++ G+ V + G++ + V Sbjct: 2153 FNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVF 2212 Query: 761 KKTLESKKVSAST------LKRDADASKAVEIVTSTSAAKTGQAKASVAKVN----KSTG 810 L S+ V ST L + + A ++ + + + + A++N + TG Sbjct: 2213 SSNLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTG 2272 Query: 811 KSASSVKSVVTVAVKGNKASIKTAK-------SGGKKSLEAKK------TGNVKNKDSNK 857 + V + +A G +A IK + +GG ++ +K G KNK+ NK Sbjct: 2273 STGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNK 2332 Query: 858 -PVTIPENSEIKTSIEV 873 P+ + ++ K + V Sbjct: 2333 EPILVDFKTDRKGLVAV 2349 Score = 54.7 bits (130), Expect = 9e-07 Identities = 117/569 (20%), Positives = 222/569 (39%), Gaps = 71/569 (12%) Query: 108 PHISASVAVKQSSVTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTP 167 P + +V+V Q S+ V+E S VQ S ++ S E+ P E + Sbjct: 1418 PVLEPAVSVLQPSMI-VSEPSVSVQESTVTVSEPAVTVS--------EQTQVIPTE-VAI 1467 Query: 168 ENMPLILRDIRMRKMGRRLPNLPSQSRN-KETLGSEAVSSNVIDYGHASKYGYTEDPLEV 226 E+ P+IL M + NL S +N +G + ++ H+ + + E+ L+ Sbjct: 1468 ESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIAL------HSGEEPHAEEHLKG 1521 Query: 227 RIYDPEIPTDEVENEFQSQQNISASVPNPNVICNS-MFPVEDVFRQMDFPGESSNNRSFF 285 Y+ E + + ++ A N +C + PV ++ + P + R+ Sbjct: 1522 DFYESE---HGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVL 1578 Query: 286 SVESGTKMSGLH---ISGGQSVLEP-IKSVNQSINQTVSQTMS---QSLIPPSMNQQPFS 338 G + S G LEP ++ I T + T+S + + S+ Q Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638 Query: 339 SELISSVSQQ--ERIPHEPVINSSNVHVG--SRGSKKNYQSQADIPIRSPFGIVKASWLP 394 +++ S S E + + ++H+ S + + ++ +P++ + A P Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698 Query: 395 KFSHADAQKMKRLPTPSMMNDYYAAS--------------PRIFPHLCSL-CNVECSHLK 439 K S +++ P ++ + ++A+ P+ L SL +E L Sbjct: 1699 KESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLA 1758 Query: 440 DWIQHQNTSTH----------IESCRQLRQQYPDW---NPEILPSRRNEGNRKENETPRR 486 + ++ ES + + Y + S++N+ NR + E ++ Sbjct: 1759 SDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK-NRDKGEKEKK 1817 Query: 487 RSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRS-RSRSPYRI 545 R S R R SS H+ R+ S R RS + HR +R RSRS R R R Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SHRSQTRSRSRSRRRRRSSRS 1876 Query: 546 RNPFRGSPKCFRSVSPERMSRR-SVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGH 604 R+ RG RSVS E+ R RS R++ + R T + + + H Sbjct: 1877 RSKSRGR----RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932 Query: 605 SPAQKPKTSSGTKP---SVKPTSATKSDS 630 +P+++ ++ S + S+ P+ +++ S Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961 >gi|116812577 LUC7-like 2 [Homo sapiens] Length = 392 Score = 61.2 bits (147), Expect = 9e-09 Identities = 49/113 (43%), Positives = 59/113 (52%), Gaps = 6/113 (5%) Query: 472 RRNEGNRKENETPRR-RSHSPSPRRSRRSSSSHRFRRSRS-PMHYMYRPRSRSPRICHRF 529 RR E R+E E RR RSHS +P+RSR S HR RSRS R RS+S HR Sbjct: 246 RREEREREEREKLRRSRSHSKNPKRSR--SREHRRHRSRSMSRERKRRTRSKSREKRHRH 303 Query: 530 ISRYRSRSRSRSPYRIRNPF--RGSPKCFRSVSPERMSRRSVRSSDRKKALED 580 SR SRSRSRS R R+ R + R S ER + + S DR ++ D Sbjct: 304 RSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRD 356 Score = 34.7 bits (78), Expect = 0.95 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 19/105 (18%) Query: 485 RRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSRSPYR 544 +R R R + RRSRS S++P+ RSRSR +R Sbjct: 238 KRNQERLKRREEREREEREKLRRSRS--------HSKNPK---------RSRSREHRRHR 280 Query: 545 IRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGT 589 R+ R + RS S E+ R RSS R ++ QRS H + Sbjct: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSH--QRSRHSS 323 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 60.5 bits (145), Expect = 2e-08 Identities = 67/203 (33%), Positives = 92/203 (45%), Gaps = 34/203 (16%) Query: 468 ILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICH 527 I PSRR+ + + TP RRS +PS RRSR S RRSR+P RSR+P Sbjct: 1951 ISPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPS-----RRSRTPSR-----RSRTPSRRR 1999 Query: 528 RFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGH 587 R S R RS S SP R+R R R S + R+ RSS+R ++ + + Sbjct: 2000 RSRSVVRRRSFSISPVRLR---RSRTPLRRRFSRSPIRRKRSRSSERGRSPKRL------ 2050 Query: 588 GTEFNKQKHLEAADKGHSPAQKPKTS----SGTKPSVKPTSATKSDSNLGGHSI-----R 638 T+ +K + LE A K ++ A K KP+ PT K GG +I + Sbjct: 2051 -TDLDKAQLLEIA-KANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEK 2108 Query: 639 CK---SKNLEDDTLSECKQVSDK 658 CK +DD + VSD+ Sbjct: 2109 CKQIAQSKEDDDVIVNKPHVSDE 2131 Score = 54.7 bits (130), Expect = 9e-07 Identities = 117/569 (20%), Positives = 222/569 (39%), Gaps = 71/569 (12%) Query: 108 PHISASVAVKQSSVTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTP 167 P + +V+V Q S+ V+E S VQ S ++ S E+ P E + Sbjct: 1418 PVLEPAVSVLQPSMI-VSEPSVSVQESTVTVSEPAVTVS--------EQTQVIPTE-VAI 1467 Query: 168 ENMPLILRDIRMRKMGRRLPNLPSQSRN-KETLGSEAVSSNVIDYGHASKYGYTEDPLEV 226 E+ P+IL M + NL S +N +G + ++ H+ + + E+ L+ Sbjct: 1468 ESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIAL------HSGEEPHAEEHLKG 1521 Query: 227 RIYDPEIPTDEVENEFQSQQNISASVPNPNVICNS-MFPVEDVFRQMDFPGESSNNRSFF 285 Y+ E + + ++ A N +C + PV ++ + P + R+ Sbjct: 1522 DFYESE---HGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVL 1578 Query: 286 SVESGTKMSGLH---ISGGQSVLEP-IKSVNQSINQTVSQTMS---QSLIPPSMNQQPFS 338 G + S G LEP ++ I T + T+S + + S+ Q Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638 Query: 339 SELISSVSQQ--ERIPHEPVINSSNVHVG--SRGSKKNYQSQADIPIRSPFGIVKASWLP 394 +++ S S E + + ++H+ S + + ++ +P++ + A P Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698 Query: 395 KFSHADAQKMKRLPTPSMMNDYYAAS--------------PRIFPHLCSL-CNVECSHLK 439 K S +++ P ++ + ++A+ P+ L SL +E L Sbjct: 1699 KESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLA 1758 Query: 440 DWIQHQNTSTH----------IESCRQLRQQYPDW---NPEILPSRRNEGNRKENETPRR 486 + ++ ES + + Y + S++N+ NR + E ++ Sbjct: 1759 SDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK-NRDKGEKEKK 1817 Query: 487 RSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRS-RSRSPYRI 545 R S R R SS H+ R+ S R RS + HR +R RSRS R R R Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SHRSQTRSRSRSRRRRRSSRS 1876 Query: 546 RNPFRGSPKCFRSVSPERMSRR-SVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGH 604 R+ RG RSVS E+ R RS R++ + R T + + + H Sbjct: 1877 RSKSRGR----RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932 Query: 605 SPAQKPKTSSGTKP---SVKPTSATKSDS 630 +P+++ ++ S + S+ P+ +++ S Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961 >gi|197276594 RNA binding motif protein 20 [Homo sapiens] Length = 1227 Score = 58.5 bits (140), Expect = 6e-08 Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 2/87 (2%) Query: 675 GSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIET 734 G V+ I LPE CTE DV L PFGKV + +++ +A+LEM + EA A+++Y + Sbjct: 517 GRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQE 576 Query: 735 TPLTIKGKSVKICVPGKKKAQNKEVKK 761 I G+ K+ + K+ + ++KK Sbjct: 577 KSAVINGE--KLLIRMSKRYKELQLKK 601 Score = 56.2 bits (134), Expect = 3e-07 Identities = 117/573 (20%), Positives = 223/573 (38%), Gaps = 101/573 (17%) Query: 1413 NQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRIS 1472 ++K P+ + + +++ E+ + P S L S S +K + R Sbjct: 710 DRKHHPRQLDKAELD-ERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYR------- 761 Query: 1473 ALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEP 1532 K K + KQ Q+ R ++D++ L E +P + KE+ Sbjct: 762 ----KEPKAKWDKYLKQQQDAPGRSR--RKDEAR---LRESRHPHPDDS------GKEDG 806 Query: 1533 LFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKN-----------VPFSELNLKK 1581 L P +V ++AKQN K K K T ++ + +E ++ Sbjct: 807 LGP----------KVTRAPEGAKAKQNE-KNKTKRTDRDQEGADDRKENTMAENEAGKEE 855 Query: 1582 KKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEE--ELNMEEMVKNS 1639 ++G +P+ V + E + E+ Q + E E NMEE+V Sbjct: 856 QEGMEESPQSVGRQEKEA---EFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV--- 909 Query: 1640 NSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESAD 1699 T+DE+ +++D I + ++ + +++D + E + V L L+ + D Sbjct: 910 ----TVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCV-----TTTLDLDLAQD 960 Query: 1700 ITFATLNTKGNEGDTVRDSIGFISSQVPED-PSTLVTVDEIQD-DSSDLHLVTLDEVTEE 1757 + GN IS + P + PS + D + L+L + E Sbjct: 961 FPKEGVKAVGN-------GAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAES 1013 Query: 1758 DED-SLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDT 1816 + SL D + ++E V E D + Q + P +++ + VD Sbjct: 1014 ETGLSLEDSDCYEKEAKGV--------ESSDVHPAPTVQQMSSPKPAEERARQPSPFVDD 1065 Query: 1817 KKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGE 1876 KT+ + G + +EE IE L + ++ + E ++ Sbjct: 1066 CKTR--GTPEDGACEGSPLEEKASPPIETDLQNQA------------CQEVLTPENSRYV 1111 Query: 1877 EAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASD--VPEELDFLVPKAGFFCPICS 1934 E + E +E E K+ + S + V S+ +P ++F+VP+ GF+C +C Sbjct: 1112 EMKSLEVRSPEY----TEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCG 1167 Query: 1935 LFYSGEK-AMTNHCKSTRHKQNTEKFMAKQRKE 1966 LFY+ E+ A +HC+S H +N +K++++ +E Sbjct: 1168 LFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE 1200 Score = 44.3 bits (103), Expect = 0.001 Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Query: 1009 RFVHLDNLPEDGL--QCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQN 1066 R VH+ NLPE V+ +GL FGKV +++ + + N+A L++ E+AQ+M + ++ Sbjct: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577 Query: 1067 PQNIGDHMLTCSLSPK 1082 I L +S + Sbjct: 578 SAVINGEKLLIRMSKR 593 Score = 43.5 bits (101), Expect = 0.002 Identities = 15/42 (35%), Positives = 24/42 (57%) Query: 413 MNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESC 454 +ND++ +P PH+CS+C+ + LKDW H H + C Sbjct: 399 LNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKC 440 Score = 40.8 bits (94), Expect = 0.013 Identities = 21/73 (28%), Positives = 45/73 (61%), Gaps = 1/73 (1%) Query: 906 VMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEI-NRKAAESMVKFYTCFP 964 V+ + NLP + +V +L PFG + + +++ S +A++E+ +AA++MV++Y Sbjct: 519 VVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKS 578 Query: 965 VLMDGNQLSISMA 977 +++G +L I M+ Sbjct: 579 AVINGEKLLIRMS 591 Score = 39.7 bits (91), Expect = 0.030 Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 15/174 (8%) Query: 1387 VSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKL------SAKEFGL- 1439 VSS K PKAK + Q + +S +D+ + S KE GL Sbjct: 749 VSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLG 808 Query: 1440 LKPTSARSGL-AESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQE-TEARP 1497 K T A G A+ + K K ++ + G+ K + + + K+ QE E P Sbjct: 809 PKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD-----DRKENTMAENEAGKEEQEGMEESP 863 Query: 1498 SIMKRDDSNNKTLAEQNTKNPKSTTGRS-SKSKEEPLFPFNLDEFVTVDEVIEE 1550 + R + + +NT+ K S S+++ E +P N++E VTVDEV EE Sbjct: 864 QSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEE 917 Score = 32.7 bits (73), Expect = 3.6 Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 7/164 (4%) Query: 1062 FLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGL----KNSPIDESEVQTAT 1117 F K+ + +G+ SL +LP +++ E PGL + P ESE + Sbjct: 961 FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPA-ESETGLSL 1019 Query: 1118 DSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEE 1177 + E + + + VQQ + E+A S F + T + E Sbjct: 1020 EDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEG 1079 Query: 1178 IPLVASASVSIEQFTENAEECALNQQMFNSD-LEKKGAEIINPK 1220 PL AS IE +N + C NS +E K E+ +P+ Sbjct: 1080 SPLEEKASPPIETDLQN-QACQEVLTPENSRYVEMKSLEVRSPE 1122 >gi|109637759 calpastatin isoform f [Homo sapiens] Length = 750 Score = 57.8 bits (138), Expect = 1e-07 Identities = 138/672 (20%), Positives = 265/672 (39%), Gaps = 58/672 (8%) Query: 1292 EKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAEKVEKMAAMKE 1351 EKT + + +K DEK+ + ++ GT A K A K ++M Sbjct: 29 EKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGA--TSKSSSMN- 85 Query: 1352 KPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKT 1411 P E K P K Q+ KP K + S+ + +K ++ P K+T Sbjct: 86 -PTETKAVKTEPEKK-SQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTE--- 140 Query: 1412 ENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTR--GGSG 1469 PK+ P+D I+A + A + + +S + P +S + G SG Sbjct: 141 ------PKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 194 Query: 1470 RISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTG--RSSK 1527 +AL + L + T++ T P + D + T E+ K + R Sbjct: 195 MDAALDDLIDTLGGPEETEEENTTYTGPEV---SDPMSSTYIEELGKREVTIPPKYRELL 251 Query: 1528 SKEEPLF--PFNLDEFVTVDEVIEEVNPSQAKQNP-LKGKRKETLKNVPFSELNLKKKKG 1584 +K+E + P + + + D+ I+ ++ +P GK+ E ++ + Sbjct: 252 AKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVR 311 Query: 1585 KTSTPRGVEGELSFVTL-DEIGEEEDAAAHLAQALVTVD----EVIDEEELNMEEMVKNS 1639 + P+ + ++ T+ D+ E A+ QA +D + +DE + E++ K Sbjct: 312 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 371 Query: 1640 NSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEI------GEVEELP 1693 DE I + + + KD L E+ + +DE+ E +E P Sbjct: 372 ED----DETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 427 Query: 1694 L--NESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTL 1751 E + + A +E R S+ I S PE P+TL + DD+ + +L Sbjct: 428 SKPTEKTEESKAAAPAPVSEA-VCRTSMCSIQSAPPE-PATL--KGTVPDDAVEALADSL 483 Query: 1752 DEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDG-DNDLKVELAQSKNDHPTDKKGNRK 1810 + + ED + +KE+ +++GE+E+ D ++E + K+ P K +++ Sbjct: 484 GKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKE 543 Query: 1811 KRAVDTKKTKLESLSQ--VGPVNENVME-EDLKTMIE-RHLTAKTPTKRVRIG----KTL 1862 + ++ L++LS+ GP N + ++ ED K + ++TP + G T Sbjct: 544 QLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS 603 Query: 1863 PSEKAVVTEPAKGEEAF--QMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELD 1920 S+K + K ++ + + DE ++D E+ + + D + +P E Sbjct: 604 QSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERD--DTIPPEYR 661 Query: 1921 FLVPKAGFFCPI 1932 L+ G P+ Sbjct: 662 HLLDDNGQDKPV 673 Score = 41.2 bits (95), Expect = 0.010 Identities = 45/144 (31%), Positives = 64/144 (44%), Gaps = 17/144 (11%) Query: 767 KKVSASTLKRDADASKA----VEIVTSTSAAKTGQAKASVAKVNKSTGKSASS--VKSVV 820 +K +AS R A A++ V TS S +K G+ K S K S G S SS Sbjct: 6 QKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGT 65 Query: 821 TVAVKGNKASIKTAKSGGKKSLEAK--KTGNVKNKDSNKPVTIPENSEIKTSIEVKATEN 878 A K + +S T+KS E K KT K S KP ++P K + + + + Sbjct: 66 ASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLP-----KQASDTGSNDA 120 Query: 879 CAKEAISDAALEATENEPLNKETE 902 K+A+S +A E +P K TE Sbjct: 121 HNKKAVSRSA----EQQPSEKSTE 140 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 55.8 bits (133), Expect = 4e-07 Identities = 61/209 (29%), Positives = 83/209 (39%), Gaps = 27/209 (12%) Query: 480 ENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRS 539 + E RR S S S R RR+ SS R RRSRS RS R H S+ RSR RS Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS----------RSRRRSH---SKSRSRRRS 287 Query: 540 RSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKA---LEDVVQRSGHGTEFNKQKH 596 +SP R R+ R + RS S R ++ + R K +RS + +++ Sbjct: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRR 347 Query: 597 LEAADKGHSPAQKPKTSSGTKPSVKPTSATKS---------DSNLGGHSIRCKSKNLEDD 647 + + + PK PS + K D S + KSK+ E D Sbjct: 348 SRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407 Query: 648 TLSECKQVSDKAVSLQRKLRKEQSLHYGS 676 E K SDK V + E+ Y S Sbjct: 408 --RERKSESDKDVKQVTRDYDEEEQGYDS 434 Score = 51.2 bits (121), Expect = 1e-05 Identities = 43/136 (31%), Positives = 61/136 (44%), Gaps = 11/136 (8%) Query: 470 PSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRF 529 P RR +R+ RRS S S R ++ + R P Y RSRS R Sbjct: 290 PRRRRSHSRERG----RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS---ASRE 342 Query: 530 ISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGT 589 R RSRS +RSP + R+P R K RS SP R + + D++++ D +RS Sbjct: 343 RRRRRSRSGTRSPKKPRSPKR---KLSRSPSPRRHKKEKKKDKDKERS-RDERERSTSKK 398 Query: 590 EFNKQKHLEAADKGHS 605 + +K K + K S Sbjct: 399 KKSKDKEKDRERKSES 414 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 54.7 bits (130), Expect = 9e-07 Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 36/185 (19%) Query: 482 ETPRRRSHSPSP----RRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRS 537 E RRS SPS R+SR SS RRSRSP R +SRSP ++ R RS Sbjct: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP-------NKERDRS 546 Query: 538 RSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHL 597 +SRSP R R SR + DR++ RS +Q Sbjct: 547 QSRSPSEERE--------------HRQSRSPSKERDRRR------WRSPSKERERRQSRS 586 Query: 598 EAADKGHSPAQKPKTSSG-TKPSV----KPTSATKSDSNLGGHSIRCKSKNLEDDTLSEC 652 + ++ HS ++ P SG ++P K S +++ S G HS S D + S Sbjct: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTV 646 Query: 653 KQVSD 657 + D Sbjct: 647 PRSPD 651 Score = 53.1 bits (126), Expect = 3e-06 Identities = 59/174 (33%), Positives = 78/174 (44%), Gaps = 22/174 (12%) Query: 471 SRRNEGNRKENE--TPRR-RSHS----PSPRRSR---RSSSSHRFRR-SRSPMHYMYRPR 519 SR + + +N+ TPRR RSH+ PS RS RSSS R R S SP R + Sbjct: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391 Query: 520 SRSPRICH-----RFISRYRSRSRSRSPYRIRNPFRG-SPK----CFRSVSPERMSRRSV 569 S SP R ++ R RSRSRSPY+ R+ R SP C RS SP + RS Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS- 450 Query: 570 RSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPT 623 RS KA + RS + + + ++ HS P + S P+ Sbjct: 451 RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504 Score = 49.7 bits (117), Expect = 3e-05 Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 19/160 (11%) Query: 472 RRNEGNRKENETPRRRSHSPSP--RRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRF 529 RR+ KE + + RS S RRSR S + R+SRSP R +SRSP Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP------ 551 Query: 530 ISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGT 589 S R +SRSP + R+ R +RS S ER R+S SS+ + + RS + Sbjct: 552 -SEEREHRQSRSPSKERDRRR-----WRSPSKERERRQSRSSSEER---DHSRSRSPNKQ 602 Query: 590 EFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSD 629 + + +K HS ++ P S S TS+ +SD Sbjct: 603 SGYSRPRASSKEKAHSRSRTP--SKEGNHSQSRTSSKESD 640 Score = 42.0 bits (97), Expect = 0.006 Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 26/200 (13%) Query: 464 WNPEILPSRRNEGNRKENET-PRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRS 522 ++P + SR N+ + P+ S S SPRRSR S R RS H R SR+ Sbjct: 257 YSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRS--HSWKRNHSRA 314 Query: 523 PRICHRFI-------SRYRSRSRSRSPYRIRNPFRG-SPKCFRSVSPERMSRRSVRSSDR 574 + I S+ RS S+ +S + R P RG S R+ S ER S RSS + Sbjct: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHS-RSSSK 373 Query: 575 KKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGG 634 +R G+ ++ + G S + P S P A + Sbjct: 374 --------ERDHRGSSSPRK------ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419 Query: 635 HSIRCKSKNLEDDTLSECKQ 654 + R +S++ + +C + Sbjct: 420 YKARDRSRSRSPNKARDCSR 439 Score = 38.5 bits (88), Expect = 0.066 Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 15/189 (7%) Query: 465 NPEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPR 524 NP SR+ + + R +S+SP+ SR S + RSR H +SRSPR Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH----SQSRSPR 288 Query: 525 ICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKAL-EDVVQ 583 R S+ R+ SR RS RN R + + + + RS + K+ + Sbjct: 289 -RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP 347 Query: 584 RSGHGTEFNKQKHLE---------AADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGG 634 R G +++ E + ++ H + P+ SG S P + Sbjct: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407 Query: 635 HSIRCKSKN 643 + R +S++ Sbjct: 408 NKARDRSRS 416 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 53.5 bits (127), Expect = 2e-06 Identities = 167/831 (20%), Positives = 320/831 (38%), Gaps = 130/831 (15%) Query: 1095 ELEKESPGLKNSPIDE----SEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEE 1150 E+ KE LK + + +E+Q S N L ++ T L E E + Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK------LKAHLEKLEVD 1142 Query: 1151 AEKATCDSDFAVETL-ELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDL 1209 K+ ++ F E L EL+ EE K ++ + S ++ E + + + N L Sbjct: 1143 LNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS---KLKTTDEEFQSLKSSHEKSNKSL 1199 Query: 1210 EKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNE 1269 E K E L + ++ + +LE +E + S T ++ ++ + Sbjct: 1200 EDKSLEFKKLSEELAIQLDICCKKT--EALLEAKTNELINISSSKTNAILSRISHCQHRT 1257 Query: 1270 T-VSE-ILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQ-I 1326 T V E +L TC V+ + + + NIS ++ + EEKE K + D++ + Sbjct: 1258 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQAT-HQLEEKENQIKSMKADIESL 1316 Query: 1327 GTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSD 1386 TEK + E + A EK + T K ++ + E K + +S Sbjct: 1317 VTEKEA-----LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1371 Query: 1387 VSSSKPSIKAVI---VSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPT 1443 +S + + +S + +A +S Q K DQ+ + LS K L K Sbjct: 1372 LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQV---QDLSFKVDTLSKEK 1428 Query: 1444 -SARSGLAESSSKF----KPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPS 1498 SA + + S+KF K QS T+ + LQ +L +K++ E + + + Sbjct: 1429 ISALEQVDDWSNKFSEWKKKAQSRFTQH-QNTVKELQIQLELK-----SKEAYEKDEQIN 1482 Query: 1499 IMKRD-DSNNKT-------LAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEV-IE 1549 ++K + D NK + + +K K + ++ K + L++ +T + IE Sbjct: 1483 LLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIE 1542 Query: 1550 EVNPSQAKQNPLKG-KRKETLKNVP-FSELNLKKKKGKTSTPRGVEGELSFVTLD----- 1602 +N N K + KE ++ + F EL G+ R E E +TL+ Sbjct: 1543 SLNEVLKNYNQQKDIEHKELVQKLQHFQEL------GEEKDNRVKEAEEKILTLENQVYS 1596 Query: 1603 ---EIGEEEDAAAHLAQALVTVDEVID--EEELNMEEMVKNSNSLFTLDELID--QDDCI 1655 E+ ++ H+ ++ + +E + E+ L E K + ++ I + + Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLL 1656 Query: 1656 SHSEPKDV--------------TVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESADIT 1701 S E K+ T L E + + +E+L +V E + E L + SA Sbjct: 1657 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSV-ESSQSETLIVPRSAKNV 1715 Query: 1702 FA-----TLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLH--------- 1747 A +++G T + I + + E L V + ++++ H Sbjct: 1716 AAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQE 1775 Query: 1748 -LVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKK 1806 L+ L+ + + + +L+EEL E+ + + +AQ +K+ Sbjct: 1776 RLIKLEHAEAKQHEDQSMIGHLQEEL-----------EEKNKKYSLIVAQH-----VEKE 1819 Query: 1807 GNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVR 1857 G K + K+ ENV ++ KT+ E+ LT + ++++ Sbjct: 1820 GG--KNNIQAKQNL-----------ENVFDDVQKTLQEKELTCQILEQKIK 1857 Score = 52.0 bits (123), Expect = 6e-06 Identities = 156/837 (18%), Positives = 317/837 (37%), Gaps = 103/837 (12%) Query: 1108 IDESEVQTATDSPSVKPNELEE--ESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETL 1165 +D + D PS +E E+ ++ S+ E L+Q+ E V Sbjct: 105 LDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAY 164 Query: 1166 ELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQM-------FNSDLEKKGAEIIN 1218 ++ Q E+ K + L S S+ + E EE ++QQ F++ LE+K I Sbjct: 165 QM-LQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISV 223 Query: 1219 PKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPST 1278 +T + LK L P D + + Q +A ++ S+ P Sbjct: 224 LQTQV----------SLLKQRLRNGPMNV-DVLKPLPQLEPQAEVFTKEENPESDGEPVV 272 Query: 1279 CIVTLVPGIPTGDEKTVDKKNISE--KKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEG 1336 T V + T ++ ++N+ + K+ KE+ T E + E+ ++ E Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332 Query: 1337 RMDAEKVEKMAAMKE-KPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIK 1395 D EK + + + A+N + + +KG+ A + +T + +++ + IK Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK 392 Query: 1396 ------------------AVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEF 1437 A KA +T KTE + K+ +QI +K S +E Sbjct: 393 QMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE- 451 Query: 1438 GLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARP 1497 R L + S+ K + + S A KL KL +++ ++ QE + Sbjct: 452 --------RISLQQELSRVKQEVVDVMKKSSEEQIA---KLQKLHEKELARKEQELTKKL 500 Query: 1498 SIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVI--EEVNPSQ 1555 +R+ +A + +++ + + +E L+E + I E N + Sbjct: 501 QTREREFQEQMKVALEKSQSEYLKISQEKEQQES----LALEELELQKKAILTESENKLR 556 Query: 1556 AKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLA 1615 Q + R L+ E +L++ K ++ ++ +A + Sbjct: 557 DLQQEAETYRTRILELESSLEKSLQENKNQSK---------------DLAVHLEAEKNKH 601 Query: 1616 QALVTVDEVIDEEELNMEEMVKNSNSLFT--LDELIDQDDCISHSEPKDVTVLSVAEEQD 1673 +TV ++++ + +E + ++L+T L L Q +E + + E++ Sbjct: 602 NKEITV--MVEKHKTELESLKHQQDALWTEKLQVLKQQ----YQTEMEKLREKCEQEKET 655 Query: 1674 LLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGDTV-------RDSIGFISSQV 1726 LLK + ++ I E+ E L E D+ L + +E V + + + Q Sbjct: 656 LLKDKEIIFQAHIEEMNEKTL-EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQT 714 Query: 1727 PEDPSTLVTVDEIQDDSSDLHLVTLDEVTEEDEDSLADFNN-LKEELNFVTVDEVGEEED 1785 + L + D+ + H +D + +E E S+ LK+++N + + ++ Sbjct: 715 DKMKQEL---EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL----LLKE 767 Query: 1786 GDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIER 1845 D LK A +N K+ + + K +S EE L + ++ Sbjct: 768 RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQK 827 Query: 1846 HLTAKTPTKRVRIGKTLPSEKAVVTEPAKGEEA--FQMSEVDEESGLKDSEPERKRK 1900 L + T+R+ + K + +A + +A Q+ ++ ++ ++SE E+K K Sbjct: 828 LLDLE--TERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 882 Score = 50.1 bits (118), Expect = 2e-05 Identities = 291/1541 (18%), Positives = 586/1541 (38%), Gaps = 283/1541 (18%) Query: 638 RCKS---KNLEDDTL--SECKQVSDKAVSLQRKLRKEQSLHYGS-VLLITELPEDGCTEE 691 RCK + E TL SE + + ++ ++L K + LH LIT+L Sbjct: 297 RCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQL-------R 349 Query: 692 DVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIETTPLTIKGKSVKICVPGK 751 D + L + + ++I +++ + +E KE A ++ +T +G+ ++ Sbjct: 350 DAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS-RIKQMTTQGEELREQKEKS 408 Query: 752 KKAQNKEVKKKTLESKKVSASTLKRDADASKAVEIVTSTSAAKTGQAKASVAKVNKSTGK 811 ++A +E++K ++K + K A+ + ++ + TS + + +++V + Sbjct: 409 ERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQE--- 465 Query: 812 SASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKN--------KDSNKPVTIPE 863 VV V K ++ I + +K L K+ K ++ K Sbjct: 466 -------VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS 518 Query: 864 NSE-IKTSIEVKATENCAKEAIS---DAALEATENE--PLNKETEEMCVMLVSNLPNKGY 917 SE +K S E + E+ A E + A L +EN+ L +E E ++ + Sbjct: 519 QSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEK 578 Query: 918 SVEEVYDLAKPFG---------GLKDILILSSHKKAYIEINRKAAESMVKFYTCFPVLMD 968 S++E + +K K+I ++ K +E + +++ + VL Sbjct: 579 SLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDAL--WTEKLQVLKQ 636 Query: 969 GNQLSISMAPENMN------IKDEEAIFITLVKENDPEANIDTIYDRFVHLDNLPEDGLQ 1022 Q + E +KD+E IF ++E + E ++ + + L++L + L Sbjct: 637 QYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMN-EKTLEKLDVKQTELESLSSE-LS 694 Query: 1023 CVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMY------SFLKQNPQNIGDHMLT 1076 VL + + + V +K +L++ Q + S +K++ +I Sbjct: 695 EVLKARHKLEE-ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI--QRTE 751 Query: 1077 CSLSPKIDLPEVQI-EHDPELEKESPGLKNSPID----ESEVQTAT---------DSPSV 1122 +L +I+ E+ + E D L++ ++N D E E+Q A+ S + Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATH 811 Query: 1123 KPNELEEESTPSIQ-------TETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVK 1175 + + EE +Q TE ++ ++ E EA+K ++ ++++ ++++ Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871 Query: 1176 EEIPLVASASVSIEQFTENAEECALNQQMFNSDL--------------EKKGAEIINPK- 1220 ++ + S+ Q E+ E +Q + +KK EI+ K Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKL 931 Query: 1221 TALLPSDSVFAEE-----RNLKGILEESPSEAEDFISGITQTMVEAVAEVEKN--ETVSE 1273 +A S + EE +N + +E+ +A++ + + +++ A+++K T E Sbjct: 932 SAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991 Query: 1274 ILP----------------STCIVTLVPGIPTGDEKTV------------DKKNISEKKG 1305 + S I V + T ++ + D +I EKK Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKL 1051 Query: 1306 NMDEKE----------EKEFNTKETRMDLQI-GTEKAEKN--------EG-RMDAEKVEK 1345 N +E EKE E + + + G EK E N EG + D E Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1111 Query: 1346 MAAMKEKPA-------ENTLFKAYPNKGVGQANKP--------DETSKTSILA------V 1384 +K+K A + T KA+ K NK ++ + +LA V Sbjct: 1112 QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKV 1171 Query: 1385 SDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTS 1444 S+++S + S + +K+ KS +++ + + K+ L Sbjct: 1172 SELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAK 1231 Query: 1445 ARSGLAESSSKFKPTQSSLTRGG-------------SGRISALQGKLSKL---------D 1482 + SSSK S ++ + +S L+ +L +L Sbjct: 1232 TNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1291 Query: 1483 YRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFV 1542 ++ T Q +E E + MK D + T E K + +S+ KE + Sbjct: 1292 FQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASE-KESCITQLK----- 1345 Query: 1543 TVDEVIEEVNPSQAKQNPLKGKRKE--------TLKNVPF-SELNLKKKKGKTSTPRGVE 1593 E+ E +N + LK K+ E T NV + ++L +K+ S+ R Sbjct: 1346 --KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQY 1403 Query: 1594 GELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDD 1653 E LD++ + L++ ++ E +D+ E K + S FT Sbjct: 1404 DEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFT--------- 1454 Query: 1654 CISHSEPKDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGD 1713 + Q+ +K+ ++ E+ E +E ++ L+ + D Sbjct: 1455 ----------------QHQNTVKELQIQL--ELKSKEAYEKDEQINLLKEELDQQNKRFD 1496 Query: 1714 TVRDSIGFISSQVPEDPSTLVT--------VDEIQD--DSSDLHLVTLDEVTEE-DEDSL 1762 ++ + S++ + S L T + E++D + + +L+EV + ++ Sbjct: 1497 CLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD 1556 Query: 1763 ADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLE 1822 + L ++L E+GEE+D +V+ A+ K + + K ++TKK +LE Sbjct: 1557 IEHKELVQKLQH--FQELGEEKDN----RVKEAEEK-ILTLENQVYSMKAELETKKKELE 1609 Query: 1823 SLSQVGPVNENVMEEDLKTM---IERHLTAK-TPTKRVRIGKTLPSEKAVVTEPAKGEEA 1878 ++ ++ EE+LK + +E AK KR K +K ++++ + EE Sbjct: 1610 HVN----LSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665 Query: 1879 FQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELDFLVPKAGFFCPICSLFYS 1938 ++ S L ER+R+ KSV S E L +VP++ + + Sbjct: 1666 YKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL--IVPRS---AKNVAAYTE 1720 Query: 1939 GEKAMTNHCKSTRHKQN--------TEKFMAKQRKEKEQNE 1971 E+A + C +++ TEK QR +E+ E Sbjct: 1721 QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEE 1761 >gi|62244004 modulator of estrogen induced transcription isoform b [Homo sapiens] Length = 1016 Score = 53.5 bits (127), Expect = 2e-06 Identities = 96/467 (20%), Positives = 176/467 (37%), Gaps = 79/467 (16%) Query: 1109 DESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELE 1168 D E+ +TD+P+ KP + + + + +E + A+ + D ++ ELE Sbjct: 64 DNIELTVSTDTPNKKPTKGKGK-------------KHEADELSGDASVEDDAFIKDCELE 110 Query: 1169 TQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINP------KTA 1222 Q ++ + + E+F EN EE ++++ +++ K+ E+I + Sbjct: 111 NQEAHEQDGNDELKDS----EEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKE 166 Query: 1223 LLPSDSVFAEERNLKGIL-----EESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPS 1277 + S + A+E L EE +E E ++ T E E+E + TV E Sbjct: 167 DIESQEIEAQEGEDDTFLTAQDGEEEENEKEGSLAEADHTAHE---EMEAHTTVKEAEDD 223 Query: 1278 TCIVTLVPG------------IPTGDEKTVDKKNISEKKGNMD------EKEEKEFNTKE 1319 VT+ + TG + S+ K D EKE K++ Sbjct: 224 NISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNA 283 Query: 1320 TRMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAE------NTLFKAYPNKGV-GQANK 1372 D K E + + VEK A K AE +TL K + G GQA Sbjct: 284 NHKD--------GKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKS 335 Query: 1373 PDETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKS---------FPKSVPR 1423 + SK S + D S S SS K + N K+ + K + Sbjct: 336 SSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSA 395 Query: 1424 DQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDY 1483 + + AK +G++ +S+ E S + G + ++G SK + Sbjct: 396 KVVTNARSPGAKCYGIVTMSSS----TEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEM 451 Query: 1484 RDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKE 1530 + + +++ +R S K++ S+ + + + K + + S+ KE Sbjct: 452 K--KENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKE 496 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 52.0 bits (123), Expect = 6e-06 Identities = 88/393 (22%), Positives = 149/393 (37%), Gaps = 34/393 (8%) Query: 1091 EHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEE 1150 E +PE E+E K SP+ + +P VK E E+E Q E + E ++ Sbjct: 496 EEEPEAEEEEVAAKKSPVKAT-------APEVKEEEGEKEEEEG-QEEEEEEDEGAKSDQ 547 Query: 1151 AEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLE 1210 AE+ + + + E E E + E + E + + ++ E +EE A +++ Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV----- 602 Query: 1211 KKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE---------A 1261 A++ P+ A P EE+ K + +SP E E S + ++ VE + Sbjct: 603 -ADAKVEKPEKAKSPVPKSPVEEKG-KSPVPKSPVE-EKGKSPVPKSPVEEKGKSPVPKS 659 Query: 1262 VAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETR 1321 E + VS+ + VP P + K+ K + KG E+EEKE Sbjct: 660 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS--KAEVG--KGEQKEEEEKEVKEAPKE 715 Query: 1322 MDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSI 1381 ++ EK + + AE K A+ E K + K + KP + K Sbjct: 716 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 775 Query: 1382 LAVSDVSSSKP-SIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGL- 1439 A + S + S K S + A + E ++ + E++ GL Sbjct: 776 KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLD 835 Query: 1440 LKPTSARSGLAESSSKF---KPTQSSLTRGGSG 1469 L P + G +S K K + + GG G Sbjct: 836 LSPADEKKGGDKSEEKVVVTKTVEKITSEGGDG 868 Score = 51.6 bits (122), Expect = 8e-06 Identities = 100/485 (20%), Positives = 179/485 (36%), Gaps = 73/485 (15%) Query: 1230 FAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPT 1289 F EE + +E+ SE E+ ++ IT+ + ++ E EK E E P Sbjct: 452 FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE-EKKEAAEEKEEE----------PE 500 Query: 1290 GDEKTVD------KKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAE----KNEGRMD 1339 +E+ V K E K EKEE+E +E D +++AE + EG + Sbjct: 501 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 560 Query: 1340 AEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKP-SIKAVI 1398 E+ E+ E AE +A K V + ++ T + V+D KP K+ + Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE---LVADAKVEKPEKAKSPV 617 Query: 1399 VSSP---KAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSK 1455 SP K K+ V K+ ++ VP+ + + K + + + + + K Sbjct: 618 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 677 Query: 1456 FK-PTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQN 1514 K P S + +G+ + + +++ + +E + K D K AE Sbjct: 678 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESP 737 Query: 1515 ------------TKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQA------ 1556 TK+ K + +K + +PL E + EE + Sbjct: 738 VKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRK 797 Query: 1557 ----------------KQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVT 1600 ++ KG +E K V + L+L K + E + T Sbjct: 798 EDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKT 857 Query: 1601 LDEI-GEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSE 1659 +++I E D A VTV + ++E E EE + ++ + + SH+ Sbjct: 858 VEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKV---------EKVTSHAI 908 Query: 1660 PKDVT 1664 K+VT Sbjct: 909 VKEVT 913 Score = 32.3 bits (72), Expect = 4.7 Identities = 57/240 (23%), Positives = 99/240 (41%), Gaps = 28/240 (11%) Query: 1752 DEVTEEDEDSLADFNNLKEELNFVTVDE-VGEEEDGDNDLKVELAQSKNDHP----TDKK 1806 +E E+E+ A + +K V +E EEE+G + + E +K+D ++K+ Sbjct: 497 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 556 Query: 1807 GNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEK 1866 G+ +K + ++ + E+ ++ E ++ K + E+ T + V K EK Sbjct: 557 GSSEKEEGEQEEGETEAEAE----GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 612 Query: 1867 AVVTEP-----AKGEEAFQMSEVDE--ESGLKDSEPERKRK----KTEDSSSGKSVASDV 1915 A P KG+ S V+E +S + S E K K K+ GKS S Sbjct: 613 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS 672 Query: 1916 PEELDFLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEER 1975 P E KA P + + KA K+ EK + + KE++ + EE+ Sbjct: 673 PVE-----EKAKSPVPKSPVEEAKSKAEVG---KGEQKEEEEKEVKEAPKEEKVEKKEEK 724 Score = 31.6 bits (70), Expect = 8.1 Identities = 62/259 (23%), Positives = 93/259 (35%), Gaps = 51/259 (19%) Query: 1080 SPKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTET 1139 SP + + + P EK + SP++E++ + K E E+E + + E Sbjct: 659 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE-EKEVKEAPKEEK 717 Query: 1140 LVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECA 1199 + ++EE ++ EK +S + E V E + + S V +E+ E EE Sbjct: 718 VEKKEEKPKDVPEKKKAES---------PVKEEAVAEVVTITKSVKVHLEK--ETKEEGK 766 Query: 1200 LNQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMV 1259 QQ + EK G E G EE S+ G + + Sbjct: 767 PLQQ--EKEKEKAGGE----------------------GGSEEEGSDKG--AKGSRKEDI 800 Query: 1260 EAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTV-----DKKNISEKKGNMDEKEEKE 1314 EVE E V + T G +EK V D EKKG D+ EEK Sbjct: 801 AVNGEVEGKEEVEQ-------ETKEKGSGREEEKGVVTNGLDLSPADEKKGG-DKSEEKV 852 Query: 1315 FNTKETRMDLQIGTEKAEK 1333 TK G + A K Sbjct: 853 VVTKTVEKITSEGGDGATK 871 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 52.0 bits (123), Expect = 6e-06 Identities = 88/393 (22%), Positives = 149/393 (37%), Gaps = 34/393 (8%) Query: 1091 EHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEE 1150 E +PE E+E K SP+ + +P VK E E+E Q E + E ++ Sbjct: 120 EEEPEAEEEEVAAKKSPVKAT-------APEVKEEEGEKEEEEG-QEEEEEEDEGAKSDQ 171 Query: 1151 AEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLE 1210 AE+ + + + E E E + E + E + + ++ E +EE A +++ Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV----- 226 Query: 1211 KKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE---------A 1261 A++ P+ A P EE+ K + +SP E E S + ++ VE + Sbjct: 227 -ADAKVEKPEKAKSPVPKSPVEEKG-KSPVPKSPVE-EKGKSPVPKSPVEEKGKSPVPKS 283 Query: 1262 VAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETR 1321 E + VS+ + VP P + K+ K + KG E+EEKE Sbjct: 284 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS--KAEVG--KGEQKEEEEKEVKEAPKE 339 Query: 1322 MDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSI 1381 ++ EK + + AE K A+ E K + K + KP + K Sbjct: 340 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 399 Query: 1382 LAVSDVSSSKP-SIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGL- 1439 A + S + S K S + A + E ++ + E++ GL Sbjct: 400 KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLD 459 Query: 1440 LKPTSARSGLAESSSKF---KPTQSSLTRGGSG 1469 L P + G +S K K + + GG G Sbjct: 460 LSPADEKKGGDKSEEKVVVTKTVEKITSEGGDG 492 Score = 51.6 bits (122), Expect = 8e-06 Identities = 100/485 (20%), Positives = 179/485 (36%), Gaps = 73/485 (15%) Query: 1230 FAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPT 1289 F EE + +E+ SE E+ ++ IT+ + ++ E EK E E P Sbjct: 76 FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE-EKKEAAEEKEEE----------PE 124 Query: 1290 GDEKTVD------KKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAE----KNEGRMD 1339 +E+ V K E K EKEE+E +E D +++AE + EG + Sbjct: 125 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 184 Query: 1340 AEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKP-SIKAVI 1398 E+ E+ E AE +A K V + ++ T + V+D KP K+ + Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE---LVADAKVEKPEKAKSPV 241 Query: 1399 VSSP---KAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSK 1455 SP K K+ V K+ ++ VP+ + + K + + + + + K Sbjct: 242 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 301 Query: 1456 FK-PTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQN 1514 K P S + +G+ + + +++ + +E + K D K AE Sbjct: 302 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESP 361 Query: 1515 ------------TKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQA------ 1556 TK+ K + +K + +PL E + EE + Sbjct: 362 VKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRK 421 Query: 1557 ----------------KQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVT 1600 ++ KG +E K V + L+L K + E + T Sbjct: 422 EDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKT 481 Query: 1601 LDEI-GEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSE 1659 +++I E D A VTV + ++E E EE + ++ + + SH+ Sbjct: 482 VEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKV---------EKVTSHAI 532 Query: 1660 PKDVT 1664 K+VT Sbjct: 533 VKEVT 537 Score = 32.3 bits (72), Expect = 4.7 Identities = 57/240 (23%), Positives = 99/240 (41%), Gaps = 28/240 (11%) Query: 1752 DEVTEEDEDSLADFNNLKEELNFVTVDE-VGEEEDGDNDLKVELAQSKNDHP----TDKK 1806 +E E+E+ A + +K V +E EEE+G + + E +K+D ++K+ Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180 Query: 1807 GNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEK 1866 G+ +K + ++ + E+ ++ E ++ K + E+ T + V K EK Sbjct: 181 GSSEKEEGEQEEGETEAEAE----GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 236 Query: 1867 AVVTEP-----AKGEEAFQMSEVDE--ESGLKDSEPERKRK----KTEDSSSGKSVASDV 1915 A P KG+ S V+E +S + S E K K K+ GKS S Sbjct: 237 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS 296 Query: 1916 PEELDFLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEER 1975 P E KA P + + KA K+ EK + + KE++ + EE+ Sbjct: 297 PVE-----EKAKSPVPKSPVEEAKSKAEVG---KGEQKEEEEKEVKEAPKEEKVEKKEEK 348 Score = 31.6 bits (70), Expect = 8.1 Identities = 62/259 (23%), Positives = 93/259 (35%), Gaps = 51/259 (19%) Query: 1080 SPKIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTET 1139 SP + + + P EK + SP++E++ + K E E+E + + E Sbjct: 283 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE-EKEVKEAPKEEK 341 Query: 1140 LVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECA 1199 + ++EE ++ EK +S + E V E + + S V +E+ E EE Sbjct: 342 VEKKEEKPKDVPEKKKAES---------PVKEEAVAEVVTITKSVKVHLEK--ETKEEGK 390 Query: 1200 LNQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMV 1259 QQ + EK G E G EE S+ G + + Sbjct: 391 PLQQ--EKEKEKAGGE----------------------GGSEEEGSDKG--AKGSRKEDI 424 Query: 1260 EAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTV-----DKKNISEKKGNMDEKEEKE 1314 EVE E V + T G +EK V D EKKG D+ EEK Sbjct: 425 AVNGEVEGKEEVEQ-------ETKEKGSGREEEKGVVTNGLDLSPADEKKGG-DKSEEKV 476 Query: 1315 FNTKETRMDLQIGTEKAEK 1333 TK G + A K Sbjct: 477 VVTKTVEKITSEGGDGATK 495 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 52.0 bits (123), Expect = 6e-06 Identities = 111/563 (19%), Positives = 203/563 (36%), Gaps = 79/563 (14%) Query: 1084 DLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQ 1143 D E + E + E+E K I E++V+ + K E +EE+ + Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE---KTTESQEETVVMSLKNGQISS 235 Query: 1144 EEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVAS--ASVSIEQFTENAEECALN 1201 EEP +EE + D E +E E + E L A + EQ + A+E A Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295 Query: 1202 QQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEA 1261 + + +++ + + + AEER + I EE AE+ + E Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEER--QRIKEEEKRAAEE----RQRIKEEE 349 Query: 1262 VAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETR 1321 E+ + + E ++K +E++ +EE++ +E + Sbjct: 350 KRAAEERQRIKE----------------------EEKRAAEERQRARAEEEEKAKVEEQK 387 Query: 1322 MDLQIGTEKAEKNEGRMDAEKVEKMAAMK---EKPAENTLFKAYPNKGVGQANKPDETSK 1378 + Q+ +K E ++ EKVE+ K EK A+ + K K E Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK------KQGEEKG 441 Query: 1379 TSILAVSD-VSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEF 1437 T + A + + KP+ K + K K E KSF + R + E K EF Sbjct: 442 TKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF---MDRKKGFTEVKSQNGEF 498 Query: 1438 GLLK-----PTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQE 1492 K T +R G +S K + + R+ L+ + + + + K Q+ Sbjct: 499 MTHKLKHTENTFSRPG-GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK 557 Query: 1493 TEAR----PSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVI 1548 + + K+ + K L E+ + + R + +EE + Sbjct: 558 QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK------------RRLK 605 Query: 1549 EEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRG----VEGELSFVTLDEI 1604 EE+ +A + E + +P L+ KK K TP+G +E F+ Sbjct: 606 EEIERRRA-------EAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 658 Query: 1605 GEEEDAAAHLAQALVTVDEVIDE 1627 + H A + +D +++ Sbjct: 659 KSSGVKSTHQAAIVSKIDSRLEQ 681 Score = 38.1 bits (87), Expect = 0.086 Identities = 83/453 (18%), Positives = 167/453 (36%), Gaps = 38/453 (8%) Query: 1231 AEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTG 1290 A ER + E + E+ G VE A+ N E +T T V G Sbjct: 38 ARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ---NSVPDEEAKTTTTNTQVEGDDEA 94 Query: 1291 D--EKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQIG-------------TEKAEKNE 1335 E+ ++ +K+ + +KEF+ T L + TEK EK+E Sbjct: 95 AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE 154 Query: 1336 GRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSD-------VS 1388 R + ++E+ + + +N A NK + + +E K ++ + Sbjct: 155 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE 214 Query: 1389 SSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSG 1448 + S + +V S K +S E ++ + D+I+ +K+ ++ + AR Sbjct: 215 KTTESQEETVVMSLK-NGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273 Query: 1449 LAESSSKFKPTQSSLTRGGSGRISALQ----GKLSKLDYRDITKQSQETEARPSIMKRDD 1504 AE + K Q RI A + + + + + + +E + +R Sbjct: 274 -AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIK 332 Query: 1505 SNNKTLAEQNTK---NPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPL 1561 K AE+ + K + KEE + +E E+ + K+N Sbjct: 333 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE-EKAKVEEQKRNKQ 391 Query: 1562 KGKRKETLKNVPFSELNLKKK-KGK-TSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALV 1619 ++K ++ +++K +GK + + E +L L + GEE+ + + Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451 Query: 1620 TVDE-VIDEEELNMEEMVKNSNSLFTLDELIDQ 1651 D+ +EE+ E++ K+ + +D+ Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR 484 Score = 37.4 bits (85), Expect = 0.15 Identities = 78/401 (19%), Positives = 156/401 (38%), Gaps = 56/401 (13%) Query: 1513 QNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNV 1572 QN TT + KS E + ++E TV + ++ + A++N + K KE Sbjct: 138 QNDTAENETTEKEEKS-ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE----- 191 Query: 1573 PFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEEELNM 1632 E K K+G E ++ + ++ E ++ ++ + ++ EE Sbjct: 192 --EEEEEKPKRGSIG-----ENQVEVMVEEKTTESQEETVVMS---LKNGQISSEEPKQE 241 Query: 1633 EEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTV-DEIGEVEE 1691 EE + S+ + +++ ++D + +E + AEE++ +K E+ + DE +E Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLE----AEERERIKAEQDKKIADERARIE- 296 Query: 1692 LPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTL 1751 A+ A + E + R+ + + E+ + ++ + Sbjct: 297 ------AEEKAAAQERERREAEE-RERMREEEKRAAEERQRIKEEEKRAAEERQ------ 343 Query: 1752 DEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKK 1811 + EE++ + + +KEE + + + KVE + +K+ KK Sbjct: 344 -RIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE------EQKRNKQLEEKK 396 Query: 1812 RAVDTKKTKLESLSQVGP---VNENVMEED-LKTMIERHLTAKTPTKRVRIGKTLPSEKA 1867 A+ K K E + Q VNE +ED L+T + + + TK + L +K Sbjct: 397 HAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKP 456 Query: 1868 VVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSG 1908 F+ E+ +E KD EP+ + K D G Sbjct: 457 T----------FKKEEIKDEKIKKDKEPKEEVKSFMDRKKG 487 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 52.0 bits (123), Expect = 6e-06 Identities = 87/437 (19%), Positives = 162/437 (37%), Gaps = 52/437 (11%) Query: 1109 DESEVQTATDSPSVKPNELEEESTPS-------IQTETLVQQEEPCEEEAEKATCDSDFA 1161 DE + D P ++ E+ ++ T IQT+ +++E +E+ + A Sbjct: 125 DEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKA 184 Query: 1162 VETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKT 1221 ++E ++ K E +A + ++ E+ + + K+ A + + Sbjct: 185 THKEKIE---KKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVK-EV 240 Query: 1222 ALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIV 1281 PS E++ + + + F + V + ++ + LP+ Sbjct: 241 QKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQAS 300 Query: 1282 TLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAE 1341 P P +EK +KK +K + +K+EKE K++ + I EK E + + Sbjct: 301 RPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQ 360 Query: 1342 KVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSS 1401 K+AA A K DE + SK + K V Sbjct: 361 GTVKIAAQ-------------------AAAKKDEKKE----------DSKKTKKPAEVEQ 391 Query: 1402 PKAKATVSK---TENQKSFPK--SVPRD-QINAEKKLSAKEFGLLKPTSARSGLAESSSK 1455 PK K K E KS K SVP D Q+ A+ + + +E G + A G E + Sbjct: 392 PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT 451 Query: 1456 FKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNT 1515 K + + + SG+ S++ + ++ + E P K+D+ +K E Sbjct: 452 -KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE-TKKDEKMSKAGKEVKP 509 Query: 1516 KNPKSTTGRSSKSKEEP 1532 K P+ K +E+P Sbjct: 510 KPPQ----LQGKKEEKP 522 Score = 51.2 bits (121), Expect = 1e-05 Identities = 94/440 (21%), Positives = 159/440 (36%), Gaps = 63/440 (14%) Query: 548 PFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPA 607 P SP ++ + + V S +KK ED+ ++S T + +K P Sbjct: 302 PTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEK--------KEPG 353 Query: 608 QKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLR 667 + +T GT +A K + S + K + + ++ +K V + + Sbjct: 354 KASETKQGTVKIAAQAAAKKDEKK--EDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPK 411 Query: 668 KEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKE----AYLEMEFKE 723 KE S +P D + + + G V+ VP +KE +E E ++ Sbjct: 412 KEHS-----------VPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRK 460 Query: 724 AITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVKK--------KTLESKKVSASTLK 775 + I IKGK K VP K + E KK K ++ K K Sbjct: 461 EKSGKTSSILKDKEPIKGKEEK--VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKK 518 Query: 776 RDADASKAVEIVTSTSAAKTGQAKASVAKVNK--STGKSASSV-KSVVTVAVKGNKASIK 832 + + + + K K + K K S GK V K V V ++ K Sbjct: 519 EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIE------K 572 Query: 833 TAKSGGKKSLEAKKTGNVKNKDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEAT 892 TAK K E ++ K ++KP P+ + T K TE KE+ A ++ Sbjct: 573 TAKPKPTKKAEHREREPPSIK-TDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHL 631 Query: 893 ENEPLNKETEEMCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKA---YIEIN 949 E ++ E + + V KP KD+ + + KKA +++ Sbjct: 632 REEKVSTRKESL-------------QLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVS 678 Query: 950 RKAAESMVKFYTCFPVLMDG 969 +S + F+ C V +DG Sbjct: 679 PTKQKSPISFFQC--VYLDG 696 Score = 40.8 bits (94), Expect = 0.013 Identities = 69/351 (19%), Positives = 120/351 (34%), Gaps = 42/351 (11%) Query: 554 KCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTS 613 K + PER + V +++K E V ++ K H E +K +KP+T Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREKE---KPEKKATHKEKIEK----KEKPETK 199 Query: 614 SGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLRKEQSLH 673 + K K +A KS+ K ++ + KQ + K +Q+ K + Sbjct: 200 TLAKEQKKAKTAEKSEEKT--------KKEVKGGKQEKVKQTAAKVKEVQKTPSKPKE-- 249 Query: 674 YGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIE 733 E+ + + + Y + ++ + K + + Sbjct: 250 ---------------KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAI---- 290 Query: 734 TTPLTIKGKSVKICVPGKKKAQNKEVKKKTLESKKVSASTLKRDADASKAVEIVTSTSAA 793 P + + P + KE +KK E K S + K D K E T+ Sbjct: 291 --PPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVE 348 Query: 794 KTGQAKASVAKVNK-STGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKN 852 K KAS K A++ K K K + + GKK E K+ Sbjct: 349 KKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQ-EKKEKHVEPA 407 Query: 853 KDSNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKETEE 903 K K ++P + ++K E +A E +I A+ + E K E+ Sbjct: 408 KSPKKEHSVPSDKQVKAKTE-RAKEEIGAVSIK-KAVPGKKEEKTTKTVEQ 456 Score = 34.3 bits (77), Expect = 1.2 Identities = 86/363 (23%), Positives = 141/363 (38%), Gaps = 69/363 (19%) Query: 1095 ELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEK- 1153 ++EK+ PG K S + V+ A + + K +E +E+S + + + Q + +E+ EK Sbjct: 346 DVEKKEPG-KASETKQGTVKIAAQA-AAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKH 403 Query: 1154 ----ATCDSDFAVET-LELETQGEEVKEEIPLV----ASASVSIEQFTENAEECALNQQM 1204 + + +V + +++ + E KEEI V A E+ T+ E+ ++ Sbjct: 404 VEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKS 463 Query: 1205 FNSDLEKKGAEIINPKTALLPSD-------------------SVFAEERNLKGILEESPS 1245 + K E I K +P+ V + L+G EE P Sbjct: 464 GKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPE 523 Query: 1246 -----EAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNI 1300 EA+ IS Q + + + EK TVS P ++ V + EKT K Sbjct: 524 PQIKKEAKPAISEKVQIHKQDIVKPEK--TVSHGKPEEKVLKQVKAVTI--EKTAKPK-- 577 Query: 1301 SEKKGNMDEKEEKEFNT-------KETRMDLQIGTEKAE------KNEGRMDAEKVEKMA 1347 KK E+E T K T + G +K E K + M + EK++ Sbjct: 578 PTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVS 637 Query: 1348 AMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAV-IVSSPKAKA 1406 KE + V +A KP SK V DV +SK + + VS K K+ Sbjct: 638 TRKE---------SLQLHNVTKAEKPARVSKD----VEDVPASKKAKEGTEDVSPTKQKS 684 Query: 1407 TVS 1409 +S Sbjct: 685 PIS 687 Score = 33.1 bits (74), Expect = 2.8 Identities = 30/135 (22%), Positives = 55/135 (40%), Gaps = 9/135 (6%) Query: 1779 EVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQ--VGPVNENVME 1836 + E + G + + A K++ D K +K V+ K K + + V P E Sbjct: 354 KASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKE 413 Query: 1837 EDLKTMIERHLTAKTPTKRVRIG-----KTLPSEKAVVTEPAKGEEAFQMSEVDEESGLK 1891 + + ++ + AKT + IG K +P +K T +E + S LK Sbjct: 414 HSVPS--DKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILK 471 Query: 1892 DSEPERKRKKTEDSS 1906 D EP + +++ +S Sbjct: 472 DKEPIKGKEEKVPAS 486 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 51.6 bits (122), Expect = 8e-06 Identities = 162/818 (19%), Positives = 317/818 (38%), Gaps = 107/818 (13%) Query: 1126 ELEEESTPSIQTETLVQQEEP---------CEEEAEKATCDSDFAVETLELETQGEEVKE 1176 +L +E Q E + QEE +++ E A + FA + L +GE++ + Sbjct: 1594 KLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQ 1653 Query: 1177 EIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTAL------LPS--DS 1228 E +A ++ + E+ A ++ L KKG ++ K L LP + Sbjct: 1654 EAEKLAQKR---KKLAKKWEKVAREEEK----LAKKGGKLAEVKNILAQKVEELPQREQN 1706 Query: 1229 VFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIP 1288 + +E+ L LEE + E+ + E VE+ + ++E Sbjct: 1707 LDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE--------------- 1751 Query: 1289 TGDEKTV--DKKNISEKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAEKVEKM 1346 +E+ + ++ +SE++ + ++EE KE + + E+ GR + +EK Sbjct: 1752 --EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKK 1809 Query: 1347 AAMKEKPAE--NTLFKAYPNKGVGQANKPDETSKTSILAVSD-VSSSKPSIKAVIVSSPK 1403 + +K N++ + NK + K K ++ + ++ K ++ Sbjct: 1810 MKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTH 1869 Query: 1404 AKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSL 1463 +K + + +N+ + E+KL+ ++ ++K + LAE+ K + SL Sbjct: 1870 SKKQLVQVKNKLGMFNKI---LAQVEEKLTQEKETVIK---KKEKLAETEKKLVQVEDSL 1923 Query: 1464 TRGGSG----------RISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQ 1513 + + +QGK DI K E +A MKR L E Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAK---EEKALNLEMKRLAEEKMRLVEG 1980 Query: 1514 NTKNPKSTTGRSSKSK-----EEPLF--PFNLDEFVTVDE----VIEEVNPSQAKQNPLK 1562 K T +S+ + E+ LF +L+E + + E +EE ++ K + Sbjct: 1981 KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTR 2040 Query: 1563 GKR---KETLKNVPFSELNLKKKKGKTSTP---RGVEGELSFVTLDE--IGEEEDAAAHL 1614 G+R + K S +KK++ + P + L +T DE + +EE + Sbjct: 2041 GQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKM 2100 Query: 1615 AQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSE-PKDVTVLSVAEEQD 1673 +AL + E L++E+ + ++ + D SE KD L+ + + Sbjct: 2101 KRAL-----FVKERRLSIEQ---------SKLDIKEWDFSEKRSELTKDEKKLARKQRKL 2146 Query: 1674 LLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTL 1733 K R++ +E EE L + + L+ + G + I F+ + + Sbjct: 2147 ANKMRRMINKEEKMTEEESKL--ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204 Query: 1734 VTVDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVE 1793 + SS + V +E E+ +SL D +E L+ +E EEE+ + + E Sbjct: 2205 RGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE---E 2261 Query: 1794 LAQSKNDHPTDKKGNRK---KRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAK 1850 + + + + +++G K K + KK K E + E V EE + M E + Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321 Query: 1851 TPTKRVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEES 1888 + + +L E E K E+ F++ E +S Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359 Score = 39.3 bits (90), Expect = 0.039 Identities = 168/923 (18%), Positives = 343/923 (37%), Gaps = 129/923 (13%) Query: 1084 DLPEVQIEHDPELEKESPGLKNSPIDESE--VQTATDSPSVKPNELEEESTPSIQTETLV 1141 D EV +E + E E K + E + +Q + E + + L Sbjct: 1540 DEEEVTLEEEVSREGEE---KEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596 Query: 1142 QQEEP-CEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 Q+EE +EE + A + A +++ E+ + A ++ Q E + A Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656 Query: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVE 1260 L KK ++ + L AE +N+ E + E + + + + Sbjct: 1657 KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716 Query: 1261 AVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKET 1320 + E+E + +E + ++ +++++G + E+++K +E Sbjct: 1717 ELEELEWDM---------------------EELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755 Query: 1321 ----RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEK-PAENTLFKAYPNKGVGQANKPDE 1375 R L K + E + EK EK+A KEK P E + + + K + Sbjct: 1756 LAWQREKLSEEETKLAQEEELLIQEK-EKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ 1814 Query: 1376 TSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAK 1435 + I ++ +++ +K +I+ K A K Q+ ++KL+ + Sbjct: 1815 KRERWINSMEELTKNK-----MILYQKKNLAQEKKNLAQE-------------KEKLAQR 1856 Query: 1436 EFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISA-LQGKLSKLDYRDITKQSQETE 1494 + LL + L S + ++ L G +I A ++ KL++ I K+ + E Sbjct: 1857 KENLLYN---KERLTHSKKQLVQVKNKL--GMFNKILAQVEEKLTQEKETVIKKKEKLAE 1911 Query: 1495 ARPSIMKRDDS---NNKTLAEQNTK---------NPKSTTGRSSKSKEEPLFPFNLDEFV 1542 +++ +DS + LA++ K K G +KEE + Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLA 1971 Query: 1543 TVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLD 1602 E++ + K+ KG+ ET + +++ + + K S Sbjct: 1972 E-----EKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL-------------- 2012 Query: 1603 EIGEEEDAAAHLAQALVTVDEVIDEEELNMEE----MVKNSNSLFTLD-ELIDQDDCISH 1657 EE H + L + I + +L V+ L +LI + + +S Sbjct: 2013 ----EEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSK 2068 Query: 1658 SEPKDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGDTVRD 1717 K +L Q L + ER +T +EI + + + + L+ + ++ D Sbjct: 2069 EPAKLNKILKAL--QKLTRDERKLTQEEIKMTK---MKRALFVKERRLSIEQSKLDIKEW 2123 Query: 1718 SIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTV 1777 S++ +D L + + +++TEE+ + L + + V + Sbjct: 2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEE-------SKLARKHSEVIL 2176 Query: 1778 DEVGEEEDGDNDLKVE--LAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVM 1835 D+ EEE G + +V L + K+G++ K ++ ++ES E+++ Sbjct: 2177 DD--EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL 2234 Query: 1836 EEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEP 1895 +E +E+ + + + R + E+ V E EE + E EE ++ E Sbjct: 2235 DE-----LEKQESLSSEEEEEREEEEEREEEEVREE----EEERKEEEEGEEKQVEKEEE 2285 Query: 1896 ERKRKKTEDSSSGKSVASDVPEELDFLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQN 1955 E+K+KK E +V EE + ++ + + S E+ C S + + Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE------TESLSDEEEEEESC-SLEEEVD 2338 Query: 1956 TEKFMAKQRKEKEQNEAEERSSR 1978 EK + K+ K+ + E +S R Sbjct: 2339 REKEILKKEKQFKLQEQRRKSLR 2361 Score = 34.3 bits (77), Expect = 1.2 Identities = 59/302 (19%), Positives = 128/302 (42%), Gaps = 51/302 (16%) Query: 1142 QQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALN 1201 ++E+ EEE++ A S+ ++ + E G E +E IP + + + A+ Sbjct: 2156 KEEKMTEEESKLARKHSEVILD--DEEEGGIEEEEVIPFLKRRW----RKRKEAKRGDKP 2209 Query: 1202 QQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEA 1261 ++ F+S +++ + S+ F+EE ++ +L+E E ++ +S + E Sbjct: 2210 KEKFSSQVDE------------VESEEHFSEE--MESLLDEL--EKQESLSSEEEEEREE 2253 Query: 1262 VAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEFNTKETR 1321 E E+ E E +E+ +++ EK+ +E+E+K+ ++ + Sbjct: 2254 EEEREEEEVREE-----------------EEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296 Query: 1322 MDLQIGTEKAEKNEGRMDAEKVEKMAAMKEK----------PAENTLFKAYPNKGVGQAN 1371 ++Q E E+ E M E+ E ++ +E+ E + K + + Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356 Query: 1372 KPDETSKTSILAV-SDVSSSK-PSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAE 1429 + + +L++ V K +I+ ++ SP K + E ++ P VP QI+ E Sbjct: 2357 RKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWE 2416 Query: 1430 KK 1431 K Sbjct: 2417 DK 2418 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 51.6 bits (122), Expect = 8e-06 Identities = 88/435 (20%), Positives = 178/435 (40%), Gaps = 44/435 (10%) Query: 1108 IDESEVQTATDSPSVKPNEL--EEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETL 1165 I++ E + S K +++ EE + + Q+EE EE + + Sbjct: 278 INKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHN--------DV 329 Query: 1166 ELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTALLP 1225 E+E GEE ++EI +V S + ++ E +E + + E + + P+ + Sbjct: 330 EIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVM-- 387 Query: 1226 SDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVP 1285 V N+K ++ + + + + + EA E+E E EI P +L P Sbjct: 388 --DVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEP-EMEFEIEPDKECKSLSP 444 Query: 1286 GIPTGDEKTVDKKNISEKKGNMD-EKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAEKVE 1344 G K+N+S +D EKE +E KE+ + + +++ ++ + Sbjct: 445 G----------KENVSA----LDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQS 490 Query: 1345 KMAAMKEKPAEN---TLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSS 1401 + + P++ +L P V Q + + V V ++ ++ V+ Sbjct: 491 QPVLQSQPPSQPEDLSLAVLQPTPQVTQ-EQGHLLPERKDFPVESVKLTEVPVEPVLTVH 549 Query: 1402 PKAKA---TVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKP 1458 P++K+ T S++ + S R + ++ S+ +S+ SG SSS+ Sbjct: 550 PESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSG--SSSSRSSS 607 Query: 1459 TQSSLTRGGSGRISALQGKLSKLDYRDITK---QSQETEARPSI-MKRDDSNNKTLAEQN 1514 + SS T G S R S+ S + R ++ +++ + R S+ KR D++ + ++ Sbjct: 608 SSSSSTSGSSSRDSS-SSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKS 666 Query: 1515 TKNPKSTTGRSSKSK 1529 +K S + SK K Sbjct: 667 SKGGSSRDTKGSKDK 681 Score = 34.7 bits (78), Expect = 0.95 Identities = 41/160 (25%), Positives = 65/160 (40%), Gaps = 11/160 (6%) Query: 471 SRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFI 530 +R R N+T + RS S S S SS+S S S R S S Sbjct: 558 TRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSS 617 Query: 531 SRYRSRSRSRSPY-RIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGT 589 SR S S S S R R+ RG + R+ RS DRK+ ++RS + Sbjct: 618 SRDSSSSTSSSSESRSRSRGRGHNR----------DRKHRRSVDRKRRDTSGLERSHKSS 667 Query: 590 EFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSD 629 + + + + +S + + ++ S + S K +S ++ D Sbjct: 668 KGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERD 707 Score = 32.3 bits (72), Expect = 4.7 Identities = 45/172 (26%), Positives = 70/172 (40%), Gaps = 31/172 (18%) Query: 1752 DEVTEEDEDSLADFNNLKEEL----NFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKG 1807 ++ E++E +A EE N V ++E GEEE+ + + A+ + + K+ Sbjct: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361 Query: 1808 NRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIE--RHLTAK---TPTKRV------ 1856 K +T+ + E P E VM D+ M+E +H+ A T RV Sbjct: 362 MEVKMEEETEVRESEKQQDSQP--EEVM--DVLEMVENVKHVIADQEVMETNRVESVEPS 417 Query: 1857 --RIGKTLPSEKAVVTEPAK-------GEE---AFQMSEVDEESGLKDSEPE 1896 K L E EP K G+E A M + EE K+SEP+ Sbjct: 418 ENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQ 469 >gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] Length = 951 Score = 51.2 bits (121), Expect = 1e-05 Identities = 40/106 (37%), Positives = 52/106 (49%), Gaps = 6/106 (5%) Query: 469 LPS--RRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRIC 526 LPS R +R + +PRRR+HSP RR RS + +R SRSP R RSRSP Sbjct: 792 LPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPT-AYRVSRSPGASRKRTRSRSP--- 847 Query: 527 HRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSS 572 H + RSRSR++S R ++ R +P S S S Sbjct: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVS 893 Score = 47.4 bits (111), Expect = 1e-04 Identities = 48/213 (22%), Positives = 79/213 (37%), Gaps = 18/213 (8%) Query: 466 PEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMH------------ 513 P+ S+ + R+E + +++ H R RS H +SRS H Sbjct: 738 PDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYR 797 Query: 514 --YMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSP-ERMSRRSVR 570 R RSRSPR R R + YR+ S K RS SP E+ +R R Sbjct: 798 TVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSR 857 Query: 571 SSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDS 630 S + KA V S + AA HS + P S G+ + + ++ Sbjct: 858 SRTKSKARSQSVSPSKQAA---PRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEA 914 Query: 631 NLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQ 663 + + + D +++ + + + +LQ Sbjct: 915 QISSAIVSSVQSKITQDLMAKVRAMLAASKNLQ 947 Score = 37.4 bits (85), Expect = 0.15 Identities = 86/401 (21%), Positives = 150/401 (37%), Gaps = 41/401 (10%) Query: 1087 EVQIEHDPELEKESPGLKNSPIDESEV---------QTATDSPSVKPNELEEESTPSIQT 1137 E + PE ++ G +P D +EV + A+ S +V +L + S I Sbjct: 523 EAPTDSAPEKPSDA-GEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISF 581 Query: 1138 ETLVQQEE--PCEEEAEKATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENA 1195 ++ + P E+ K DSD E+ E + P VA V +E+ Sbjct: 582 AIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQL 641 Query: 1196 EECALNQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGIT 1255 + L + LE + A K A +S +E+ L+ E +A F+ + Sbjct: 642 TQEELEAKQAKQKLEDRLAAAAREKLAQASKES---KEKQLQA---ERKRKAALFLQTLK 695 Query: 1256 QTMVEAVAEVEKNETVSEILPSTCIVTLVPG---IPTGDEKTVDKKNISEKKGNMDEKEE 1312 + EA A + S ST L+ G +PT + K D+ + K +E++E Sbjct: 696 NPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKE 755 Query: 1313 KEFNTKETRMDLQIGTEK---AEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQ 1369 K+ + R + + K + K+ R ++ + + + P + + Sbjct: 756 KKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRR---R 812 Query: 1370 ANKPDETSKTSILAVSDVSSSKP--SIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQIN 1427 A+ P+ + + + S P S K SP K K +S KS R Q Sbjct: 813 AHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEK---KKKRRSRSRTKSKARSQSV 869 Query: 1428 AEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGS 1468 + K +A +P + + A S+S P +S RG S Sbjct: 870 SPSKQAAP-----RPAAPAAHSAHSAS-VSPVES---RGSS 901 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 51.2 bits (121), Expect = 1e-05 Identities = 111/597 (18%), Positives = 232/597 (38%), Gaps = 81/597 (13%) Query: 1431 KLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQS 1490 KL K LLK +A +F+ T+ L + + K +L+ + +T Sbjct: 834 KLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKS--------EAKRKELEEKMVTLLK 885 Query: 1491 QETEARPSIMKRDDS--NNKTLAEQNTKNPKSTTGR----SSKSKEEPLFPFNL------ 1538 ++ + + + DS + + EQ KN + + +++EE L Sbjct: 886 EKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRK 945 Query: 1539 --DEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGEL 1596 DE + + I+++ + AK K + +KN+ L + K S + E Sbjct: 946 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005 Query: 1597 SFVTLDEIGEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCIS 1656 TLD++ EED L +A +++ +D+ E ++E+ K L ++ D ++ Sbjct: 1006 HQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065 Query: 1657 HSEPKDVTVLSVAEEQDLLKQE----RLVTVDEIGEVEELPLNESADITFATLNTKGNEG 1712 D+ ++ L K+E L++ E + E+ L + A + G E Sbjct: 1066 QESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 1125 Query: 1713 DTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEEL 1772 + R S Q + L + E +++ E ++ A+F L+ +L Sbjct: 1126 EAERASRAKAEKQRSDLSRELEEISERLEEAGG----ATSAQVELNKKREAEFQKLRRDL 1181 Query: 1773 NFVTVD-----------------EVGEEEDGDNDLKVELAQSKNDHPTDKKG-NRKKRAV 1814 T+ E+GE+ D +K +L + K++ + + A+ Sbjct: 1182 EEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAI 1241 Query: 1815 DTKKTKLESL--SQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIG---KTLPSEKAVV 1869 K LE + S V+E +E+ + + LTA+ + G + L + A+V Sbjct: 1242 SKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALV 1301 Query: 1870 TEPAKGEEAFQMS------EVDEESGLKDS----------EPERKRKKTEDSSSGKSVAS 1913 ++ ++ ++A +++EE+ K++ + + R++ E+ GK+ Sbjct: 1302 SQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKA--- 1358 Query: 1914 DVPEELDFLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQN 1970 EL + KA + K T+ + T + +K +A++ +E E++ Sbjct: 1359 ----ELQRALSKAN-----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEH 1406 >gi|109637771 calpastatin isoform l [Homo sapiens] Length = 654 Score = 50.8 bits (120), Expect = 1e-05 Identities = 125/605 (20%), Positives = 237/605 (39%), Gaps = 55/605 (9%) Query: 1353 PAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKTE 1412 P E K P K Q+ KP K + S+ + +K ++ P K+T Sbjct: 3 PTETKAVKTEPEKK-SQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTE---- 57 Query: 1413 NQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTR--GGSGR 1470 PK+ P+D I+A + A + + +S + P +S + G SG Sbjct: 58 -----PKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGM 112 Query: 1471 ISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKE 1530 +AL + L + T++ T P + D + T E+ K + + + Sbjct: 113 DAALDDLIDTLGGPEETEEENTTYTGPEV---SDPMSSTYIEELGKREVTIPPKYRELLA 169 Query: 1531 EPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPR 1590 +P+ P + + ++ D +P+ A + K + E LK S ++ R Sbjct: 170 KPIGPDDAIDALSSDFTCG--SPTAAGKKTEKEESTEVLK--AQSAGTVRSAAPPQEKKR 225 Query: 1591 GVEGELSFVTLDEIGEEEDAAAHLAQALVTVD----EVIDEEELNMEEMVKNSNSLFTLD 1646 VE + D+ E A+ QA +D + +DE + E++ K D Sbjct: 226 KVEKD---TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGED----D 278 Query: 1647 ELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEI------GEVEELPL--NESA 1698 E I + + + KD L E+ + +DE+ E +E P E Sbjct: 279 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 338 Query: 1699 DITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTLDEVTEED 1758 + + A +E R S+ I S PE P+TL + DD+ + +L + + Sbjct: 339 EESKAAAPAPVSEA-VCRTSMCSIQSAPPE-PATL--KGTVPDDAVEALADSLGKKEADP 394 Query: 1759 EDSLADFNNLKEELNFVTVDEVGEEEDG-DNDLKVELAQSKNDHPTDKKGNRKKRAVDTK 1817 ED + +KE+ +++GE+E+ D ++E + K+ P K ++++ ++ Sbjct: 395 EDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSE 454 Query: 1818 KTKLESLSQ--VGPVNENVME-EDLKTMIE-RHLTAKTPTKRVRIG----KTLPSEKAVV 1869 L++LS+ GP N + ++ ED K + ++TP + G T S+K + Sbjct: 455 DFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 514 Query: 1870 TEPAKGEEAF--QMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELDFLVPKAG 1927 K ++ + + DE ++D E+ + + D + +P E L+ G Sbjct: 515 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERD--DTIPPEYRHLLDDNG 572 Query: 1928 FFCPI 1932 P+ Sbjct: 573 QDKPV 577 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 50.8 bits (120), Expect = 1e-05 Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 23/196 (11%) Query: 479 KENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSR 538 K NE RS S + +SR SS SH RR RS + R +RS SR + R R Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHS-RRKRSQSKHRSRSHNRSR-------SRQKDRRR 350 Query: 539 SRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLE 598 S+SP++ R+ R R SR S D++K + ++ E +++K E Sbjct: 351 SKSPHKKRSKSR----------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 400 Query: 599 AADKGHSPAQKPKTSSGTKPSVKPTSATKS-----DSNLGGHSIRCKSKNLEDDTLSECK 653 + ++ K K K K + R K K E D E + Sbjct: 401 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 460 Query: 654 QVSDKAVSLQRKLRKE 669 + K + +RK K+ Sbjct: 461 KDRSKEIDEKRKKDKK 476 Score = 38.9 bits (89), Expect = 0.050 Identities = 49/208 (23%), Positives = 81/208 (38%), Gaps = 23/208 (11%) Query: 443 QHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSS 502 + + H + + +++ D E R E + K + + R+ S SRRS SS Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493 Query: 503 HRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPE 562 R RR R R SRSPR S+ R SRSP SP+ + Sbjct: 494 SRERRRRRS-----RSSSRSPR-----TSKTIKRKSSRSP---------SPRSRNKKDKK 534 Query: 563 RMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKP 622 R R S R++ +++S + + ++ + K SS +K V Sbjct: 535 REKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK-EVDD 593 Query: 623 TSATKSDSNLGGHSIRCKSKNLEDDTLS 650 A +++ N H+ C+ L ++ LS Sbjct: 594 KDAPRTEENKIQHNGNCQ---LNEENLS 618 Score = 35.4 bits (80), Expect = 0.56 Identities = 56/240 (23%), Positives = 94/240 (39%), Gaps = 36/240 (15%) Query: 1292 EKTVDKKNISEKKGNMDEKEEKE-----------FNTKETRMDLQIGTEKAEKNEGRMDA 1340 EK +K+ + EK + + EKE KE D + EK + E + Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 441 Query: 1341 EKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVS----DVSSSKPSIKA 1396 EK KE+ E K +K + + K D+ S+T + + SSS+ + Sbjct: 442 EKDRDKEKEKEQDKEKEREKD-RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500 Query: 1397 VIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKF 1456 SS ++ T SKT +KS PR + +KK + R ++E + Sbjct: 501 RSRSSSRSPRT-SKTIKRKSSRSPSPRSRNKKDKKREKE----------RDHISERRERE 549 Query: 1457 KPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARP--SIMKRDDSNNKTLAEQN 1514 + T S+ + + R GK KL+ + + +E P S+ K D + E+N Sbjct: 550 RST--SMRKSSNDR----DGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 602 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 50.8 bits (120), Expect = 1e-05 Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 23/196 (11%) Query: 479 KENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSR 538 K NE RS S + +SR SS SH RR RS + R +RS SR + R R Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHS-RRKRSQSKHRSRSHNRSR-------SRQKDRRR 234 Query: 539 SRSPYRIRNPFRGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLE 598 S+SP++ R+ R R SR S D++K + ++ E +++K E Sbjct: 235 SKSPHKKRSKSR----------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 284 Query: 599 AADKGHSPAQKPKTSSGTKPSVKPTSATKS-----DSNLGGHSIRCKSKNLEDDTLSECK 653 + ++ K K K K + R K K E D E + Sbjct: 285 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 344 Query: 654 QVSDKAVSLQRKLRKE 669 + K + +RK K+ Sbjct: 345 KDRSKEIDEKRKKDKK 360 Score = 38.9 bits (89), Expect = 0.050 Identities = 49/208 (23%), Positives = 81/208 (38%), Gaps = 23/208 (11%) Query: 443 QHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKENETPRRRSHSPSPRRSRRSSSS 502 + + H + + +++ D E R E + K + + R+ S SRRS SS Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377 Query: 503 HRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPE 562 R RR R R SRSPR S+ R SRSP SP+ + Sbjct: 378 SRERRRRRS-----RSSSRSPR-----TSKTIKRKSSRSP---------SPRSRNKKDKK 418 Query: 563 RMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKP 622 R R S R++ +++S + + ++ + K SS +K V Sbjct: 419 REKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK-EVDD 477 Query: 623 TSATKSDSNLGGHSIRCKSKNLEDDTLS 650 A +++ N H+ C+ L ++ LS Sbjct: 478 KDAPRTEENKIQHNGNCQ---LNEENLS 502 Score = 35.4 bits (80), Expect = 0.56 Identities = 56/240 (23%), Positives = 94/240 (39%), Gaps = 36/240 (15%) Query: 1292 EKTVDKKNISEKKGNMDEKEEKE-----------FNTKETRMDLQIGTEKAEKNEGRMDA 1340 EK +K+ + EK + + EKE KE D + EK + E + Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 325 Query: 1341 EKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVS----DVSSSKPSIKA 1396 EK KE+ E K +K + + K D+ S+T + + SSS+ + Sbjct: 326 EKDRDKEKEKEQDKEKEREKD-RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384 Query: 1397 VIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKF 1456 SS ++ T SKT +KS PR + +KK + R ++E + Sbjct: 385 RSRSSSRSPRT-SKTIKRKSSRSPSPRSRNKKDKKREKE----------RDHISERRERE 433 Query: 1457 KPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARP--SIMKRDDSNNKTLAEQN 1514 + T S+ + + R GK KL+ + + +E P S+ K D + E+N Sbjct: 434 RST--SMRKSSNDR----DGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 486 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 50.4 bits (119), Expect = 2e-05 Identities = 128/592 (21%), Positives = 218/592 (36%), Gaps = 53/592 (8%) Query: 1094 PELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEK 1153 PE + P + +SE + S K + EE T Q V +EE E+EA++ Sbjct: 423 PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEE--EKEAKE 480 Query: 1154 ATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLE--K 1211 + E E E GEE + P +AS E + EE + + + E K Sbjct: 481 EEGKEEEGGEEEEAEG-GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539 Query: 1212 KGAEIINPKTALLPS--------DSVFAEERNLKGILE-ESPSEAEDFISGITQTMVEAV 1262 AE+ +P+ A P+ ++ E+ K E +SP +A+ ++ EA Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599 Query: 1263 AEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEF--NTKET 1320 + + V E S P +E + S +K KEE + K Sbjct: 600 SPEKAKSPVKEEAKSPAEAKS----PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655 Query: 1321 RMDLQIGTEKAEKNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTS 1380 + EKA K+ + +A+ EK + + A++ P K +A P++ Sbjct: 656 EKEEAKSPEKA-KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE--EAKSPEKAKSPV 712 Query: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKT----ENQKSFPKSVPRDQINAEKKLSAKE 1436 +K +K + KAK+ V + E KS K+ D + E K AKE Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772 Query: 1437 FGLLK----PTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQE 1492 P A+S + E + +S L A + ++ K ++ K + Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK----APEKEIPK---KEEVKSPVK 825 Query: 1493 TEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVN 1552 E +P +K + K E+ PK+ + SK +E P + +V E+ Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP------KKEAPKPKVEEKKE 879 Query: 1553 PS--QAKQNPLKGKRKET--LKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEE 1608 P+ + K++ ++ K++E K VP E K+ K + + + E + Sbjct: 880 PAVEKPKESKVEAKKEEAEDKKKVPTPE---KEAPAKVEVKEDAKPKEKTEVAKK--EPD 934 Query: 1609 DAAAHLAQALVTVDEVIDEEELNMEEMVKNSNSLFTLDELIDQDDCISHSEP 1660 DA A E E++ EE K + +DD EP Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986 Score = 47.4 bits (111), Expect = 1e-04 Identities = 97/435 (22%), Positives = 167/435 (38%), Gaps = 54/435 (12%) Query: 1045 KAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSP-KIDLPEVQIEHDPELEKESPGL 1103 K+ + SPE A+S ++P + + SP ++ PE + + + E +SP Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE-KAKSPTKEEAKSPEK 651 Query: 1104 KNSPIDE---------SEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKA 1154 SP E S V+ SP + ++ E+ + ++ V++E E+A+ Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK-- 709 Query: 1155 TCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGA 1214 S E E VKEE A +++ ++ E+ ++ D++ A Sbjct: 710 ---SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766 Query: 1215 EIINPKTALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEI 1274 + + A P+D F E+ K ++E E S + + E+ K E V Sbjct: 767 KTPAKEEARSPADK-FPEKA--KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS- 822 Query: 1275 LPSTCIVTLVPGIPTGDE--------KTVDKKNISEKKGNMDEKEEKEFNTKETRMDLQI 1326 P +E K KK EK + EEK+ + KE + Sbjct: 823 -------------PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA 869 Query: 1327 GTEKAE-KNEGRMDAEKVEKMAAMKEKPAEN----TLFKAYPNK-GVGQANKPDETSKTS 1380 K E K E ++ K K+ A KE+ + T K P K V + KP E ++ + Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929 Query: 1381 ILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLL 1440 D + +PS A K +A K + ++ K P ++ E K + L Sbjct: 930 KKEPDDAKAKEPSKPA-----EKKEAAPEKKDTKEEKAKK-PEEKPKTEAKAKEDDKTLS 983 Query: 1441 K-PTSARSGLAESSS 1454 K P+ ++ AE SS Sbjct: 984 KEPSKPKAEKAEKSS 998 Score = 45.1 bits (105), Expect = 7e-04 Identities = 95/464 (20%), Positives = 167/464 (35%), Gaps = 42/464 (9%) Query: 1082 KIDLPEVQIEHDPELEKESPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLV 1141 ++ PE E K P K+ +E++ SP + +EE+ + ++ Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602 Query: 1142 QQEEPCEEEAEK-ATCDSDFAVETLELETQGEEVKEEIPLVASASVSIEQFTENAEECAL 1200 + + P +EEA+ A S E K + P A S E+ +E A Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK-SPEKAKSPEKEEAK 661 Query: 1201 NQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKGILEE---SPSEAEDFISGITQT 1257 + + S ++ AE +P+ A P + K ++E SP +A+ + ++ Sbjct: 662 SPEKAKSPVK---AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718 Query: 1258 MVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDE-KTVDKKNISEKKGNMDEK--EEKE 1314 +A + V++ E S P +E K+ +K EK +D K E K Sbjct: 719 PEKAKSPVKEEAKTPEKAKS----------PVKEEAKSPEKAKSPEKAKTLDVKSPEAKT 768 Query: 1315 FNTKETRMDLQIGTEKAEK--NEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKG-VGQAN 1371 +E R EKA+ E EK + K E + K K V + Sbjct: 769 PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828 Query: 1372 KPDETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKK 1431 KP E V +P KA KA AT E + S + P+ + K Sbjct: 829 KPQE-----------VKVKEPPKKA---EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874 Query: 1432 LSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQ 1491 KE + KP ++ + ++ K + + ++ + K K+ Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934 Query: 1492 ETEA----RPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEE 1531 + +A +P+ K K E+ K P+ +K+KE+ Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978 Score = 42.0 bits (97), Expect = 0.006 Identities = 88/455 (19%), Positives = 172/455 (37%), Gaps = 68/455 (14%) Query: 470 PSRRNEGNRKENETP-RRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHR 528 P + + E ++P + + SP+ +S + S ++SP +++SP Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP------EKAKSPE---- 656 Query: 529 FISRYRSRSRSRSPYRIRNPFRGSPKCFRSVSPERMS---RRSVRSSDRKKALEDVVQRS 585 + ++SP + ++P + K SPE+ + +S ++ K+ +S Sbjct: 657 -------KEEAKSPEKAKSPVKAEAK-----SPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704 Query: 586 GHGTEFNKQKHLEAADKGHSPA-QKPKTSSGTKPSVKPT--SATKSDSNLGGHSIRCKSK 642 + ++ ++ +K SP ++ KT K VK S K+ S ++ KS Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764 Query: 643 NLEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGSVLLITELPEDGCT--EEDVRKLFQPF 700 + E + +DK + KE+ + PE + +ED + + Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEE----------VKSPEKAKSPLKEDAKAPEKEI 814 Query: 701 GKVNDVLIVPYRKEAYLEMEFKEAIT-AIMKYIETTPLTIKGKSVKICVPGKKKAQNKEV 759 K +V +E E++ KE A + TP T + K K KK+A +V Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874 Query: 760 KKKT-----------LESKKVSASTLKRDADASKAVEIVTSTSAAKTGQAKASVAKVNKS 808 ++K +E+KK A K+ K + K VAK Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934 Query: 809 TGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKNKDSNKPVTIPENSEIK 868 K A + +K + K + KK + +K K KP T + E Sbjct: 935 DAK-----------AKEPSKPAEKKEAAPEKKDTKEEKA----KKPEEKPKTEAKAKEDD 979 Query: 869 TSIEVKATENCAKEAISDAALEATENEPLNKETEE 903 ++ + ++ A++A ++ + +++P K TE+ Sbjct: 980 KTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014 Score = 41.6 bits (96), Expect = 0.008 Identities = 156/775 (20%), Positives = 284/775 (36%), Gaps = 131/775 (16%) Query: 1162 VETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKG-AEIINPK 1220 V T + + EE+ E + + + +E + +L +Q S+LE + A+I + + Sbjct: 306 VNTDAMRSAQEEITEYRRQLQARTTELEALKSTKD--SLERQ--RSELEDRHQADIASYQ 361 Query: 1221 TALLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAE---VEKNETVSEILPS 1277 A+ D AE RN K + E +D ++ +E A +E E P Sbjct: 362 EAIQQLD---AELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPI 418 Query: 1278 TCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEKEF-----NTKETRMDLQIGTEKAE 1332 +L G+P + K SE+K + EK EKE T+ET++ ++ TE+ E Sbjct: 419 P--FSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV-TEEEE 475 Query: 1333 KNEGRMDAEKVEKMAAMKEKPAENTLFKAYPNKGVGQANKPDETSKTSILAVSDVSSSKP 1392 K E + + K E+ +E K+ P + +A P++ +K+ V + + S Sbjct: 476 K-EAKEEEGKEEEGGEEEEAEGGEEETKSPPAE---EAASPEKEAKSP---VKEEAKSPA 528 Query: 1393 SIKAVIVSSPKAKATVSKTENQKSFPKSV---PRDQINAEKKLSAKEFGLLKPTSARSGL 1449 K+ K+ A V E KS K P + + EK+ + + P A+S Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588 Query: 1450 AESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKT 1509 E + +S + A +K ++ K E ++ + + + Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA--KSPTKEEA 646 Query: 1510 LAEQNTKNPKSTTGRSSKSKEEPLFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETL 1569 + + K+P+ +S + + P+ E +P +AK +P+K + K Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV-------------KAEAKSPEKAK-SPVKAEAKSPE 692 Query: 1570 K-NVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVID-- 1626 K P E +K K+ +E E A + + + T ++ Sbjct: 693 KAKSPVKEEAKSPEKAKSPVK------------EEAKSPEKAKSPVKEEAKTPEKAKSPV 740 Query: 1627 EEELNMEEMVKNSNSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEI 1686 +EE E K+ TLD + E + K+E D+ Sbjct: 741 KEEAKSPEKAKSPEKAKTLD-------------------VKSPEAKTPAKEEARSPADKF 781 Query: 1687 GEVEELPLNESADITFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDL 1746 E + P+ E + + +++ ++P+ V E + Sbjct: 782 PEKAKSPVKEE-------VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE-- 832 Query: 1747 HLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKK 1806 V + E ++ E+ A EE D K E A K + P K Sbjct: 833 --VKVKEPPKKAEEEKAPATPKTEE---------------KKDSKKEEAPKK-EAPKPKV 874 Query: 1807 GNRKKRAVDT-KKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSE 1865 +K+ AV+ K++K+E+ + ED K K PT K P+ Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEA--------EDKK---------KVPTPE----KEAPA- 912 Query: 1866 KAVVTEPAKGEEAFQMS--EVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEE 1918 K V E AK +E +++ E D+ + S+P K++ + K + PEE Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967 Score = 38.9 bits (89), Expect = 0.050 Identities = 120/614 (19%), Positives = 213/614 (34%), Gaps = 91/614 (14%) Query: 751 KKKAQNKEVKKKT----LESKKVSASTLKRDADASKAVEIVTSTSAAKTGQAKASVAKVN 806 +K+A+ +E K++ E++ T A+ + + E + + ++ A Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534 Query: 807 KSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKNKDSNKPVTIPENSE 866 K KS + VKS + + ++ + EAK VK+ + K P E Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS---PAKEE 591 Query: 867 IKTSIEVKATENCAKEAISDAALEATENEPLNKETEEMCVMLVSNLPNKGYSVEEVYDLA 926 K+ E K+ E AK + + A E + KE + + S K + EE Sbjct: 592 AKSPAEAKSPEK-AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650 Query: 927 KPFGGLKDILILSSHKKAYIEINRKAAESMVKFYTCFPVLMDGNQLSISMAPENMNIKDE 986 K K+ K+ ++ K+ E PV + + +P K Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS-----PVKAEAKSPEKAKSPVKEEAKSP 705 Query: 987 EAIFITLVKE-NDPEANIDTIYDRFVHLDNLPEDGLQCVLCVGLQFGKVDHHVFISNRNK 1045 E + +E PE + + PE V K Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEA----KTPEKAKSPV----------------KEEAK 745 Query: 1046 AILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGLKN 1105 + + SPE A+++ + + + SP PE + + + E +SP Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEE----ARSPADKFPE-KAKSPVKEEVKSPEKAK 800 Query: 1106 SPIDESEVQTATDSPS---VKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAV 1162 SP+ E + P VK EEE ++ + E P + E EKA Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK-----EPPKKAEEEKAPA------ 849 Query: 1163 ETLELETQGEEVKEEIPLVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTA 1222 T + E + + KEE P + +E+ E A E + S +E K E + K Sbjct: 850 -TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE-----KPKESKVEAKKEEAEDKKKV 903 Query: 1223 LLPSDSVFAEERNLKGILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVT 1282 P +E+P++ E V+ A+ ++ V++ P Sbjct: 904 PTPE--------------KEAPAKVE----------VKEDAKPKEKTEVAKKEPDDAKAK 939 Query: 1283 LVPGIPTGDEKTVDKKNIS-EKKGNMDEKEEKEFNTKETRMDLQIGTEKAEKNEGRMDAE 1341 K +KK + EKK +EK +K +T + + K + AE Sbjct: 940 -------EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992 Query: 1342 KVEKMAAMKEKPAE 1355 K EK ++ +K ++ Sbjct: 993 KAEKSSSTDQKDSK 1006 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.126 0.344 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,679,144 Number of Sequences: 37866 Number of extensions: 3751870 Number of successful extensions: 21031 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 631 Number of HSP's that attempted gapping in prelim test: 16185 Number of HSP's gapped (non-prelim): 4065 length of query: 1978 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1861 effective length of database: 13,817,196 effective search space: 25713801756 effective search space used: 25713801756 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.