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Search of human proteins with 61966919
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
(1035 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 2180 0.0
gi|118601070 hypothetical protein LOC158724 [Homo sapiens] 624 e-178
gi|22749289 hypothetical protein LOC170062 [Homo sapiens] 614 e-175
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 157 5e-38
gi|160707881 formin 2 [Homo sapiens] 130 8e-30
gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens] 127 5e-29
gi|211971092 hypothetical protein LOC100129583 [Homo sapiens] 123 8e-28
gi|110349719 titin isoform N2-A [Homo sapiens] 111 3e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 108 2e-23
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 108 2e-23
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 108 2e-23
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 108 2e-23
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 103 6e-22
gi|116284392 mucin 2 precursor [Homo sapiens] 97 1e-19
gi|47132519 Ras association and pleckstrin homology domains 1 is... 93 1e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 92 2e-18
gi|55750053 atrophin-1 [Homo sapiens] 87 1e-16
gi|55750041 atrophin-1 [Homo sapiens] 87 1e-16
gi|150170670 piccolo isoform 2 [Homo sapiens] 84 9e-16
gi|150378539 piccolo isoform 1 [Homo sapiens] 84 9e-16
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 82 3e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 82 3e-15
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 82 3e-15
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 80 1e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 79 3e-14
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 78 5e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 77 6e-14
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 77 8e-14
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 75 4e-13
gi|18079216 CASK interacting protein 1 [Homo sapiens] 74 9e-13
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 2180 bits (5650), Expect = 0.0
Identities = 1035/1035 (100%), Positives = 1035/1035 (100%)
Query: 1 MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY 60
MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY
Sbjct: 1 MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY 60
Query: 61 GCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEE 120
GCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEE
Sbjct: 61 GCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEE 120
Query: 121 VEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGK 180
VEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGK
Sbjct: 121 VEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGK 180
Query: 181 YPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPE 240
YPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPE
Sbjct: 181 YPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPE 240
Query: 241 TGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPE 300
TGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPE
Sbjct: 241 TGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPE 300
Query: 301 TGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPE 360
TGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPE
Sbjct: 301 TGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPE 360
Query: 361 TRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPK 420
TRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPK
Sbjct: 361 TRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPK 420
Query: 421 IGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
IGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE
Sbjct: 421 IGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
Query: 481 KDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE 540
KDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE
Sbjct: 481 KDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE 540
Query: 541 SSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPE 600
SSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPE
Sbjct: 541 SSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPE 600
Query: 601 TGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPK 660
TGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPK
Sbjct: 601 TGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPK 660
Query: 661 TRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPE 720
TRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPE
Sbjct: 661 TRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPE 720
Query: 721 SRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPK 780
SRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPK
Sbjct: 721 SRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPK 780
Query: 781 PRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVS 840
PRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVS
Sbjct: 781 PRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVS 840
Query: 841 DSLQRRHTSRKLRDFKWAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYS 900
DSLQRRHTSRKLRDFKWAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYS
Sbjct: 841 DSLQRRHTSRKLRDFKWAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYS 900
Query: 901 MELDEMDEVKFFSQEKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDP 960
MELDEMDEVKFFSQEKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDP
Sbjct: 901 MELDEMDEVKFFSQEKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDP 960
Query: 961 KLVLEKPDEPDILDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQ 1020
KLVLEKPDEPDILDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQ
Sbjct: 961 KLVLEKPDEPDILDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQ 1020
Query: 1021 VYKYKEDVTDASEED 1035
VYKYKEDVTDASEED
Sbjct: 1021 VYKYKEDVTDASEED 1035
>gi|118601070 hypothetical protein LOC158724 [Homo sapiens]
Length = 791
Score = 624 bits (1610), Expect = e-178
Identities = 374/671 (55%), Positives = 422/671 (62%), Gaps = 95/671 (14%)
Query: 410 RISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPET 469
+ + + +EP K CL+PP+T SHL PEPPETGVSHL PEPPKT VSSL EPPET
Sbjct: 171 KTTEVPTEPGKHPCGEFCLKPPETPVSHLLPEPPETGVSHLSPEPPKTPVSSLRPEPPET 230
Query: 470 GVSHLCPEPPEKDVSHLRPEPPDT------------------------------GVSHLC 499
GVSHL PEPPE VSH+RP PP T +
Sbjct: 231 GVSHLRPEPPETGVSHIRPGPPITRRRSSLLRQLLKLDSERKLEDARAPCEGREKTTDEP 290
Query: 500 PEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLR 559
EP K P P ET +SHLR EPPK VSS LRPEPPETG SHLR
Sbjct: 291 TEPGKYPCGKFCPRPFETPLSHLRQEPPKTPVSS------------LRPEPPETGESHLR 338
Query: 560 PEPPKTRM-YSLRPEPPDTGVSHLCPEPPKT-RVSSLPPEPPETGVSHLCPEPPETRVSH 617
E KTR SLR EP +TGVS L PPKT R SSL EP +TGVSHL PEPP+T VSH
Sbjct: 339 LEHSKTRRGSSLRSEPSETGVSRLRLAPPKTRRGSSLHAEPSKTGVSHLSPEPPKTEVSH 398
Query: 618 LRPEPPETGVSHLRPEPPKTR------MYSLRPEPPNTGVSHLCPE-PPKTRVSSLPPEP 670
L P PP+TGV HLR EPP T +Y L+ + + + + + P EP
Sbjct: 399 LHPVPPKTGVCHLRLEPPDTSQVSNLLLYILKVLDSGRTLKDVWDRCEARVKKTKEPTEP 458
Query: 671 PETGVSHLCPEPPETRVSHLRPEPPET-GVSRLHPEPPKT-RVSSLHAEPPESRVSHLCP 728
++ C +PPET+VSH PE P+T S LH +PPKT R SSL +EPP++R
Sbjct: 459 HKSPCGEPCLQPPETQVSHPHPEHPKTRRRSSLHSQPPKTRRTSSLRSEPPKTR------ 512
Query: 729 EPPETGVSHLRPEPPKPR-VSSLRPEPLET-RVSHLRPEPPET-GVSHLHPELPKPRVSS 785
S LR EPPK R SSL PEP +T RVS LRPE P++ VS LHPE PK S
Sbjct: 513 -----RTSSLRSEPPKTRRTSSLGPEPPKTRRVSSLRPELPKSRRVSSLHPEPPKAPESH 567
Query: 786 LHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSDSLQR 845
EPPK R AS++KEL QE T ST ECVSDSLQ
Sbjct: 568 QFSEPPKIR--------------------------ASYIKELLQEDTPSTKECVSDSLQY 601
Query: 846 RHTSRKLRD-FKWAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYSMELD 904
R+TS KLR+ FKWAGDLG +EESI +LFDFTP+ RAT++DQK KK ECSS LKYSMELD
Sbjct: 602 RYTSEKLREFFKWAGDLGADEESIRNLFDFTPKYRATHEDQKFKKVKECSSELKYSMELD 661
Query: 905 EMDEVKFFSQEKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDPKLVL 964
E DE KFFSQEK K NS++AQ VKM YGAWYLKPKL KKLRSDEPLIDPKL+L
Sbjct: 662 EKDEDKFFSQEKYWGRKFHTPSNSYTAQRVKMKYGAWYLKPKLWKKLRSDEPLIDPKLLL 721
Query: 965 EKPDEPDILDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQVYKY 1024
+KPDEPD+LD LYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAM YKY
Sbjct: 722 KKPDEPDVLDDLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMIFYKY 781
Query: 1025 KEDVTDASEED 1035
KE + +ASEED
Sbjct: 782 KE-IVEASEED 791
Score = 574 bits (1479), Expect = e-163
Identities = 339/581 (58%), Positives = 375/581 (64%), Gaps = 94/581 (16%)
Query: 1 MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY 60
MGDQR QD SPGMDS PWYC+K PSK FAK KHRRLRFPP+DTQNWVFV EGMDDFRY
Sbjct: 1 MGDQRLQDWLRSPGMDSKPWYCNKRPSKCFAKCKHRRLRFPPMDTQNWVFVKEGMDDFRY 60
Query: 61 GCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEE 120
GC SPEDTLVCRRDEFLLPKISLRGPQADPKS +KKLLKKAALFSKLSPAQ ARKAFVE+
Sbjct: 61 GCPSPEDTLVCRRDEFLLPKISLRGPQADPKSGQKKLLKKAALFSKLSPAQLARKAFVEQ 120
Query: 121 VEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDA-GSCEGQEKTTDEPTEPG 179
VEAQLM KHPLAMYPNLGEDMPPDLLLQVLK LDPER+LEDA CE QEKTT+ PTEPG
Sbjct: 121 VEAQLMAKHPLAMYPNLGEDMPPDLLLQVLKHLDPERELEDAWACCETQEKTTEVPTEPG 180
Query: 180 KYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPP 239
K+PCGEF +PPET VS L PEPP+T VS L PEPP+T VS LRP+PP+T VS L EPP
Sbjct: 181 KHPCGEFCLKPPETPVSHLLPEPPETGVSHLSPEPPKTPVSSLRPEPPETGVSHLRPEPP 240
Query: 240 ETGVSHLRPEPPKTQVSSLHL--------------------------------------- 260
ETGVSH+RP PP T+ S L
Sbjct: 241 ETGVSHIRPGPPITRRRSSLLRQLLKLDSERKLEDARAPCEGREKTTDEPTEPGKYPCGK 300
Query: 261 ---EPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSH-------------LHREPPETGVP 304
P ET +SHL EPP T VS L PEPP+T SH L EP ETGV
Sbjct: 301 FCPRPFETPLSHLRQEPPKTPVSSLRPEPPETGESHLRLEHSKTRRGSSLRSEPSETGVS 360
Query: 305 DLCLEPPKS-RVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPET-- 361
L L PPK+ R S L EPS+TGVSHL PEPPKT VS LHP PP+TGV HL EPP+T
Sbjct: 361 RLRLAPPKTRRGSSLHAEPSKTGVSHLSPEPPKTEVSHLHPVPPKTGVCHLRLEPPDTSQ 420
Query: 362 ---------------------------RVSPLRQ--LPPEAGVSHLCPEPPKTRVPPLRP 392
RV ++ P ++ C +PP+T+V P
Sbjct: 421 VSNLLLYILKVLDSGRTLKDVWDRCEARVKKTKEPTEPHKSPCGEPCLQPPETQVSHPHP 480
Query: 393 ETPK-NGVSPLFPEPPKT-RISNLRSEPPKI-GVSHLCLEPPKT-RGSHLRPEPPET-GV 447
E PK S L +PPKT R S+LRSEPPK S L EPPKT R S L PEPP+T V
Sbjct: 481 EHPKTRRRSSLHSQPPKTRRTSSLRSEPPKTRRTSSLRSEPPKTRRTSSLGPEPPKTRRV 540
Query: 448 SHLRPEPPKT-RVSSLHLEPPETGVSHLCPEPPEKDVSHLR 487
S LRPE PK+ RVSSLH EPP+ SH EPP+ S+++
Sbjct: 541 SSLRPELPKSRRVSSLHPEPPKAPESHQFSEPPKIRASYIK 581
Score = 259 bits (663), Expect = 7e-69
Identities = 191/436 (43%), Positives = 221/436 (50%), Gaps = 84/436 (19%)
Query: 286 PPKTRVSHLHREPPETGVPDL--CLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLH 343
PP + L PE + D C E + + + + EP + +PP+T VS L
Sbjct: 142 PPDLLLQVLKHLDPERELEDAWACCET-QEKTTEVPTEPGKHPCGEFCLKPPETPVSHLL 200
Query: 344 PEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETP-------- 395
PEPPETGVSHL PEPP+T VS LR PPE GVSHL PEPP+T V +RP P
Sbjct: 201 PEPPETGVSHLSPEPPKTPVSSLRPEPPETGVSHLRPEPPETGVSHIRPGPPITRRRSSL 260
Query: 396 ----------------------------------KNGVSPLFPEPPKTRISNLRSEPPKI 421
K P P +T +S+LR EPPK
Sbjct: 261 LRQLLKLDSERKLEDARAPCEGREKTTDEPTEPGKYPCGKFCPRPFETPLSHLRQEPPKT 320
Query: 422 GVSHLCLEPPKT-------------RGSHLRPEPPETGVSHLRPEPPKT-RVSSLHLEPP 467
VS L EPP+T RGS LR EP ETGVS LR PPKT R SSLH EP
Sbjct: 321 PVSSLRPEPPETGESHLRLEHSKTRRGSSLRSEPSETGVSRLRLAPPKTRRGSSLHAEPS 380
Query: 468 ETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKT-RVSHLRP-------------- 512
+TGVSHL PEPP+ +VSHL P PP TGV HL EPP T +VS+L
Sbjct: 381 KTGVSHLSPEPPKTEVSHLHPVPPKTGVCHLRLEPPDTSQVSNLLLYILKVLDSGRTLKD 440
Query: 513 --EPSETGVSHLR--PEPPKILVSSLHQAPPESSVSHLRPEPPET-GVSHLRPEPPKT-R 566
+ E V + EP K PPE+ VSH PE P+T S L +PPKT R
Sbjct: 441 VWDRCEARVKKTKEPTEPHKSPCGEPCLQPPETQVSHPHPEHPKTRRRSSLHSQPPKTRR 500
Query: 567 MYSLRPEPPDT-GVSHLCPEPPKT-RVSSLPPEPPET-GVSHLCPEPPET-RVSHLRPEP 622
SLR EPP T S L EPPKT R SSL PEPP+T VS L PE P++ RVS L PEP
Sbjct: 501 TSSLRSEPPKTRRTSSLRSEPPKTRRTSSLGPEPPKTRRVSSLRPELPKSRRVSSLHPEP 560
Query: 623 PETGVSHLRPEPPKTR 638
P+ SH EPPK R
Sbjct: 561 PKAPESHQFSEPPKIR 576
Score = 227 bits (579), Expect = 4e-59
Identities = 154/328 (46%), Positives = 177/328 (53%), Gaps = 101/328 (30%)
Query: 145 LLLQVLKPLDPERKLEDAGS-CEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPP 203
LL Q+LK LD ERKLEDA + CEG+EKTTDEPTEPGKYPCG+F PRP ET +S L EPP
Sbjct: 260 LLRQLLK-LDSERKLEDARAPCEGREKTTDEPTEPGKYPCGKFCPRPFETPLSHLRQEPP 318
Query: 204 KTPVSSLRPEPPETGVSHLRPQ-------------------------PPKTQV-SSLHLE 237
KTPVSSLRPEPPETG SHLR + PPKT+ SSLH E
Sbjct: 319 KTPVSSLRPEPPETGESHLRLEHSKTRRGSSLRSEPSETGVSRLRLAPPKTRRGSSLHAE 378
Query: 238 PPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTG-VSHL-------------- 282
P +TGVSHL PEPPKT+VS LH PP+TGV HL LEPP T VS+L
Sbjct: 379 PSKTGVSHLSPEPPKTEVSHLHPVPPKTGVCHLRLEPPDTSQVSNLLLYILKVLDSGRTL 438
Query: 283 ----------------------------CPEPPKTRVSH-------------LHREPPET 301
C +PP+T+VSH LH +PP+T
Sbjct: 439 KDVWDRCEARVKKTKEPTEPHKSPCGEPCLQPPETQVSHPHPEHPKTRRRSSLHSQPPKT 498
Query: 302 G-VPDLCLEPPKSR-VSHLRPEPSETG-VSHLHPEPPKTL--------------VSSLHP 344
L EPPK+R S LR EP +T S L PEPPKT VSSLHP
Sbjct: 499 RRTSSLRSEPPKTRRTSSLRSEPPKTRRTSSLGPEPPKTRRVSSLRPELPKSRRVSSLHP 558
Query: 345 EPPETGVSHLCPEPPETRVSPLRQLPPE 372
EPP+ SH EPP+ R S +++L E
Sbjct: 559 EPPKAPESHQFSEPPKIRASYIKELLQE 586
>gi|22749289 hypothetical protein LOC170062 [Homo sapiens]
Length = 645
Score = 614 bits (1584), Expect = e-175
Identities = 331/530 (62%), Positives = 376/530 (70%), Gaps = 46/530 (8%)
Query: 526 PPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTG---VSHL 582
PP +L+ L Q PE + E + T + P ++G
Sbjct: 142 PPDLLLQVLKQLDPERKL--------EDAWARCEAREKTTEV------PTESGKYPCGES 187
Query: 583 CPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSL 642
CP PP+T VS L P+ P+T VS PEPP+TR LRPEPP+T VS L PEPP+TR L
Sbjct: 188 CPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSLRPEPPKTRVSSLHPEPPETRASHL 247
Query: 643 RPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRL 702
R +PP TGVSHLCPEPPKT VSS+ PEPP+TG SHLCPEPPETRVSHL PE PETGVS L
Sbjct: 248 RVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPEPPETRVSHLHPESPETGVSHL 307
Query: 703 HPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPL----ETR 758
PEP KT+VSSL EPPE+ VSHLC EPP T RVSS + L E +
Sbjct: 308 RPEPSKTQVSSLCPEPPEAGVSHLCLEPPNT-----------HRVSSFLLQVLKLDSEKK 356
Query: 759 VSHLR----------PEPPETGVSHLHPELPKP---RVSSLHLEPPKTRRVSSLRLEPPK 805
+ R E + G H P+P R+ L L P TRR++SL L+PPK
Sbjct: 357 LEDARARCEGQEMTTEELTKPGKYHFWESCPRPFESRMPHLRLVLPITRRMASLCLKPPK 416
Query: 806 TGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSDSLQRRHTSRKLRDFKWAGDLGVNE 865
T RVSSLCPEPTKTGASHLKELFQE T STMECVSDSLQRRHTSRKLRDFKWAGDLGVNE
Sbjct: 417 TRRVSSLCPEPTKTGASHLKELFQEDTPSTMECVSDSLQRRHTSRKLRDFKWAGDLGVNE 476
Query: 866 ESISSLFDFTPECRATYQDQKNKKANECSSGLKYSMELDEMDEVKFFSQEKDLDGKIQNA 925
ESISSLFDFTPECR T QDQK KKANEC+S L Y MELD+MDEV+F + K D + + A
Sbjct: 477 ESISSLFDFTPECRTTDQDQKIKKANECASRLMYGMELDDMDEVEFL-RIKYWDRRRRAA 535
Query: 926 PNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDPKLVLEKPDEPDILDGLYGPIAFKDF 985
P+S+SAQ ++ YG WY +PKLGKKLRSDEPLIDPK VLEKPDEPDILDGLYGPIAFKDF
Sbjct: 536 PHSYSAQRGRIRYGPWYFEPKLGKKLRSDEPLIDPKPVLEKPDEPDILDGLYGPIAFKDF 595
Query: 986 ILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQVYKYKEDVTDASEED 1035
ILSKGY MPG+I++LFA++GWTYDSVKTPIQRA+QVYKYKEDVTDAS+ED
Sbjct: 596 ILSKGYRMPGVIEKLFAKKGWTYDSVKTPIQRAVQVYKYKEDVTDASKED 645
Score = 568 bits (1463), Expect = e-161
Identities = 301/437 (68%), Positives = 328/437 (75%), Gaps = 13/437 (2%)
Query: 1 MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY 60
MGD+RPQDRP S GMDS PWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY
Sbjct: 1 MGDRRPQDRPRSQGMDSKPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRY 60
Query: 61 GCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEE 120
CQSPEDTLVCRRDEFLLPKISLRGPQAD KSRKKKLLKKAALFS+LSP QPARKAFVEE
Sbjct: 61 ACQSPEDTLVCRRDEFLLPKISLRGPQADRKSRKKKLLKKAALFSELSPVQPARKAFVEE 120
Query: 121 VEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDA-GSCEGQEKTTDEPTEPG 179
VEAQLMTKHPLAMYPNLG+DMPPDLLLQVLK LDPERKLEDA CE +EKTT+ PTE G
Sbjct: 121 VEAQLMTKHPLAMYPNLGKDMPPDLLLQVLKQLDPERKLEDAWARCEAREKTTEVPTESG 180
Query: 180 KYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPP 239
KYPCGE PRPPET VS L P+ PKTPVSS RPEPP+T LRP+PPKT+VSSLH EPP
Sbjct: 181 KYPCGESCPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSLRPEPPKTRVSSLHPEPP 240
Query: 240 ETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPP 299
ET SHLR +PP+T VS L EPP+T VS ++ EPP TG SHLCPEPP+TRVSHLH E P
Sbjct: 241 ETRASHLRVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPEPPETRVSHLHPESP 300
Query: 300 ETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKT--------LVSSLHPEPPETGV 351
ETGV L EP K++VS L PEP E GVSHL EPP T V L E
Sbjct: 301 ETGVSHLRPEPSKTQVSSLCPEPPEAGVSHLCLEPPNTHRVSSFLLQVLKLDSEKKLEDA 360
Query: 352 SHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETP-KNGVSPLFPEPPKT- 409
C E E L + P + CP P ++R+P LR P ++ L +PPKT
Sbjct: 361 RARC-EGQEMTTEELTK-PGKYHFWESCPRPFESRMPHLRLVLPITRRMASLCLKPPKTR 418
Query: 410 RISNLRSEPPKIGVSHL 426
R+S+L EP K G SHL
Sbjct: 419 RVSSLCPEPTKTGASHL 435
Score = 253 bits (647), Expect = 5e-67
Identities = 145/272 (53%), Positives = 164/272 (60%), Gaps = 54/272 (19%)
Query: 499 CPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHL 558
CP PP+T VS LRP+ +T VS RPEPPK SL RPEPP+T VS L
Sbjct: 188 CPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSL------------RPEPPKTRVSSL 235
Query: 559 RPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL 618
PEPP+TR LR +PP+TGVSHLCPEPPKT VSS+ PEPP+TG SHLCPEPPETRVSHL
Sbjct: 236 HPEPPETRASHLRVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPEPPETRVSHL 295
Query: 619 RPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKT-RVSSL----------- 666
PE PETGVSHLRPEP KT++ SL PEPP GVSHLC EPP T RVSS
Sbjct: 296 HPESPETGVSHLRPEPSKTQVSSLCPEPPEAGVSHLCLEPPNTHRVSSFLLQVLKLDSEK 355
Query: 667 ---------------PPEPPETGVSHL---CPEPPETRVSHLRPEPPET-GVSRLHPEPP 707
E + G H CP P E+R+ HLR P T ++ L +PP
Sbjct: 356 KLEDARARCEGQEMTTEELTKPGKYHFWESCPRPFESRMPHLRLVLPITRRMASLCLKPP 415
Query: 708 KTRVSSLHAEPPESRVSHLCPEPPETGVSHLR 739
KTR RVS LCPEP +TG SHL+
Sbjct: 416 KTR-----------RVSSLCPEPTKTGASHLK 436
Score = 238 bits (608), Expect = 2e-62
Identities = 143/262 (54%), Positives = 162/262 (61%), Gaps = 23/262 (8%)
Query: 368 QLPPEAG---VSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVS 424
++P E+G CP PP+T V LRP+ PK VS PEPPKTR +LR EPPK VS
Sbjct: 174 EVPTESGKYPCGESCPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSLRPEPPKTRVS 233
Query: 425 HLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVS 484
L EPP+TR SHLR +PPETGVSHL PEPPKT VSS+H EPP+TG SHLCPEPPE VS
Sbjct: 234 SLHPEPPETRASHLRVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPEPPETRVS 293
Query: 485 HLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKI--LVSSLHQAPPESS 542
HL PE P+TGVSHL PEP KT+VS L PEP E GVSHL EPP + S L Q S
Sbjct: 294 HLHPESPETGVSHLRPEPSKTQVSSLCPEPPEAGVSHLCLEPPNTHRVSSFLLQVLKLDS 353
Query: 543 VSHL-----RPEPPETGVSHLR-----------PEPPKTRMYSLRPEPPDT-GVSHLCPE 585
L R E E L P P ++RM LR P T ++ LC +
Sbjct: 354 EKKLEDARARCEGQEMTTEELTKPGKYHFWESCPRPFESRMPHLRLVLPITRRMASLCLK 413
Query: 586 PPKT-RVSSLPPEPPETGVSHL 606
PPKT RVSSL PEP +TG SHL
Sbjct: 414 PPKTRRVSSLCPEPTKTGASHL 435
Score = 235 bits (599), Expect = 2e-61
Identities = 139/279 (49%), Positives = 163/279 (58%), Gaps = 44/279 (15%)
Query: 408 KTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPP 467
+ + + + +E K C PP+T S LRP+ P+T VS RPEPPKTR SL EPP
Sbjct: 169 REKTTEVPTESGKYPCGESCPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSLRPEPP 228
Query: 468 ETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPP 527
+T VS L PEPPE SHLR +PP+TGVSHLCPEPPKT VS + PEP +TG SHL PE
Sbjct: 229 KTRVSSLHPEPPETRASHLRVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPE-- 286
Query: 528 KILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPP 587
PPE+ VSHL PE PETGVSHLRPEP KT++ SL PEPP+ GVSHLC EPP
Sbjct: 287 ----------PPETRVSHLHPESPETGVSHLRPEPSKTQVSSLCPEPPEAGVSHLCLEPP 336
Query: 588 KT-RVSSL--------------------------PPEPPETGVSHL---CPEPPETRVSH 617
T RVSS E + G H CP P E+R+ H
Sbjct: 337 NTHRVSSFLLQVLKLDSEKKLEDARARCEGQEMTTEELTKPGKYHFWESCPRPFESRMPH 396
Query: 618 LRPEPPET-GVSHLRPEPPKT-RMYSLRPEPPNTGVSHL 654
LR P T ++ L +PPKT R+ SL PEP TG SHL
Sbjct: 397 LRLVLPITRRMASLCLKPPKTRRVSSLCPEPTKTGASHL 435
Score = 226 bits (577), Expect = 7e-59
Identities = 128/250 (51%), Positives = 158/250 (63%), Gaps = 10/250 (4%)
Query: 283 CPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSL 342
CP PP+T VS L + P+T V EPPK+R LRPEP +T VS LHPEPP+T S L
Sbjct: 188 CPRPPETPVSRLRPQLPKTPVSSRRPEPPKTRAPSLRPEPPKTRVSSLHPEPPETRASHL 247
Query: 343 HPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPL 402
+PPETGVSHLCPEPP+T VS + PP+ G SHLCPEPP+TRV L PE+P+ GVS L
Sbjct: 248 RVDPPETGVSHLCPEPPKTLVSSVHPEPPDTGASHLCPEPPETRVSHLHPESPETGVSHL 307
Query: 403 FPEPPKTRISNLRSEPPKIGVSHLCLEPPKT-RGSHLRPEPPETGVSHLRPEPPKTRVSS 461
PEP KT++S+L EPP+ GVSHLCLEPP T R S + + S + E + R
Sbjct: 308 RPEPSKTQVSSLCPEPPEAGVSHLCLEPPNTHRVSSFLLQVLKLD-SEKKLEDARARCEG 366
Query: 462 LHL---EPPETGVSHL---CPEPPEKDVSHLRPEPPDT-GVSHLCPEPPKT-RVSHLRPE 513
+ E + G H CP P E + HLR P T ++ LC +PPKT RVS L PE
Sbjct: 367 QEMTTEELTKPGKYHFWESCPRPFESRMPHLRLVLPITRRMASLCLKPPKTRRVSSLCPE 426
Query: 514 PSETGVSHLR 523
P++TG SHL+
Sbjct: 427 PTKTGASHLK 436
Score = 75.5 bits (184), Expect = 2e-13
Identities = 50/93 (53%), Positives = 60/93 (64%), Gaps = 16/93 (17%)
Query: 146 LLQVLKPLDPERKLEDAGS-CEGQEKTTDEPTEPGKYPCGEFSPRPPETRV--------- 195
LLQVLK LD E+KLEDA + CEGQE TT+E T+PGKY E PRP E+R+
Sbjct: 345 LLQVLK-LDSEKKLEDARARCEGQEMTTEELTKPGKYHFWESCPRPFESRMPHLRLVLPI 403
Query: 196 ----SCLPPEPPKTP-VSSLRPEPPETGVSHLR 223
+ L +PPKT VSSL PEP +TG SHL+
Sbjct: 404 TRRMASLCLKPPKTRRVSSLCPEPTKTGASHLK 436
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 157 bits (397), Expect = 5e-38
Identities = 221/764 (28%), Positives = 289/764 (37%), Gaps = 140/764 (18%)
Query: 164 SCEGQEK----TTDEPTEPGKYPCG---------EFSPR---PPETRVSCLPP--EPPKT 205
+C+GQ K T+ +P EPG C + P+ P + LPP E P +
Sbjct: 391 ACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS 450
Query: 206 PVSSLRPEPPETGVSHLRPQPPKTQVS----SLHLE----------PPETGVSHLRPEPP 251
P P P S L P P + S +LHL PPE S L P P
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE--SPLSPPPE 508
Query: 252 KTQVSSLH---LEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCL 308
+ S L L PPE LE P L P P + +S E P + P+
Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALETP------LSPPPEASPLSPPFEESPLSPPPEELP 562
Query: 309 EPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEP----PETGVSHLCPEPPETRVS 364
P S L P P E+ +S PP+ S PE P S L P P E+ +S
Sbjct: 563 TSPPPEASRLSPPPEESPMS----PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
Query: 365 PLRQLPPEAGVSHLCPEP---PKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKI 421
P PPEA S L P P P + P P +P VS L P P +R+S E P
Sbjct: 619 P----PPEA--SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672
Query: 422 GVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEK 481
P S L P P ++ S PP+ +S PPE + L P E+
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTS----PPPEDSPAS---PPPEDSLMSL---PLEE 722
Query: 482 DVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPES 541
PE P LC P++ HL P P E +S RPE P + P++
Sbjct: 723 SPLLPLPEEP-----QLC---PRSEGPHLSPRPEEPHLSP-RPEEPHL--------SPQA 765
Query: 542 SVSHLRPEPPETGVSHLRPEP---PKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP 598
HL P+P E + + EP P+ L P+P + HL P+ + +S +P EP
Sbjct: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL---HLSPQTEEPHLSPVPEEP 822
Query: 599 ---PETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLC 655
P+ SHL P+ E +S P P E SHL PE K + S RPE P C
Sbjct: 823 CLSPQPEESHLSPQSEEPCLS---PRPEE---SHLSPELEKPPL-SPRPEKPPEEPGQ-C 874
Query: 656 PEPPKTRVSSLPPEP---PETGVSHLCPEPPETRVSHLRPEPP--ETGVSRLHPE----- 705
P P + + P EP P G L EP E +S L E P +G L P+
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPAL-SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD 933
Query: 706 ---PPKTRVSSLHAEPPESRVSHL----------CPEPPETGVSHLRPEPPKPRVSSLRP 752
PP + + + A P S + L PE P P P P + P
Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDP 993
Query: 753 EPLETRVSHLRPEPPETGVSHLHPELPKPRVSSL-------HLEPPKTRRVSSLRLEPPK 805
EP+ + P P S + E P+ S L PP +L L P
Sbjct: 994 EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP- 1052
Query: 806 TGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSDSLQRRHTS 849
S L P G S EL + T E +L+ TS
Sbjct: 1053 ----SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092
Score = 150 bits (379), Expect = 6e-36
Identities = 189/630 (30%), Positives = 248/630 (39%), Gaps = 109/630 (17%)
Query: 199 PPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
PPEP TP + P+ + QP V+S+ +P E G +P + +
Sbjct: 374 PPEPGDTPT-----DEPDALYVACQGQPKGGHVTSM--QPKEPGPLQCEAKP--LGKAGV 424
Query: 259 HLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHL 318
LEP LE P L P P ++ +S E P + P S L
Sbjct: 425 QLEPQ--------LEAPLNEEMPLLPPPEESPLSPPPEESPTS---------PPPEASRL 467
Query: 319 RPEPSETGVSHLHPEP---PKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQ---LPPE 372
P P E S L PE + L S PPE S L P P + SPL + PPE
Sbjct: 468 SPPPEELPASPL-PEALHLSRPLEESPLSPPPEE--SPLSPPPESSPFSPLEESPLSPPE 524
Query: 373 AGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPK 432
E P + P P +P SPL P P + S PP+ L PP
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP----TSPPPEAS----RLSPPP 576
Query: 433 TRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPD 492
S + P P E+ +S P P +R+ E P + P P + S L P P D
Sbjct: 577 EE-SPMSPPPEESPMS---PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 493 TGVS---HLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPE 549
+ +S P P VS L P P VS L P P + +S PPE S P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPV---VSRLSPPPEESPLS----PPPEES-----PT 680
Query: 550 PPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE 609
P S L P P + P P D+ S PP+ + SLP E E+ + L E
Sbjct: 681 SPPPEASRLSPPPEDS---PTSPPPEDSPAS----PPPEDSLMSLPLE--ESPLLPLPEE 731
Query: 610 P---PETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSL 666
P P + HL P P E HL P P + + EP HL P+P + + ++
Sbjct: 732 PQLCPRSEGPHLSPRPEE---PHLSPRPEEPHLSPQAEEP------HLSPQPEEPCLCAV 782
Query: 667 PPEP---PETGVSHLCPEP------PETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAE 717
P EP P+ HL P+P P+T HL P P E +S P+P ++ +S
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS---PQPEESHLS----- 834
Query: 718 PPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEP----PETGVSH 773
P+S L P P E SHL PE KP +S +P E PE P G
Sbjct: 835 -PQSEEPCLSPRPEE---SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS 890
Query: 774 LHPELPKPRVSSLHLEPPKTRRVSSLRLEP 803
L P L +P +S EPP + L L P
Sbjct: 891 LSPLLGEPALSEPG-EPPLSPLPEELPLSP 919
Score = 108 bits (270), Expect = 3e-23
Identities = 205/732 (28%), Positives = 272/732 (37%), Gaps = 126/732 (17%)
Query: 139 EDMPPDLLLQV-------LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKY-PCGEFSPRP 190
E+ PP L+ PL P + E S +E T P E + P E SP
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFE-ESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
Query: 191 PETRVSCLPPEP------PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVS 244
P S + P P P S L P P E S L P P +++S + P +
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEE---SPLSPPPEASRLSPPPEDSPMSPPP 639
Query: 245 HLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVP 304
P P +VS L P VS L P P ++ +S E P + P
Sbjct: 640 EESPMSPPPEVSRL---------------SPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
Query: 305 DLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVS 364
+ P S P P ++ S P P +L+S E P L P P E ++
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPAS---PPPEDSLMSLPLEESP------LLPLPEEPQLC 735
Query: 365 PLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVS 424
P + P HL P P + + P RPE P L P+ + +S EP V
Sbjct: 736 PRSEGP------HLSPRPEEPHLSP-RPEEPH-----LSPQAEEPHLSPQPEEPCLCAVP 783
Query: 425 HLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEP---PETGVSHLCPEPPEK 481
P+ G HL P+P E HL P+ + +S + EP P+ SHL P+ E
Sbjct: 784 EEPHLSPQAEGPHLSPQPEEL---HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 482 DVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPE--PSETGVSHLRPEPPKILVSSLHQAPP 539
+S P P + SHL PE K +S RPE P E G P P ++ L P
Sbjct: 841 CLS---PRPEE---SHLSPELEKPPLSP-RPEKPPEEPGQC---PAPEEL---PLFPPPG 887
Query: 540 ESSVSHLRPEP--PETGVSHLRPEPPKTRMY-----SLRPE--PPDTGVSHLCPEPPKTR 590
E S+S L EP E G L P P + + SL P+ PPD L P
Sbjct: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
Query: 591 VSSLPP----EPPETGVSHLCPEPP------ETRVSHLRPEPPETGVSHLRPEPPKTRMY 640
+L P E P PE P ET +S PPE + P PP
Sbjct: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS----PPPEANCTDPEPVPPMILPP 1003
Query: 641 SLRPEPPNTGVSHLCPEP------PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
S P P S + EP P + S +P P + S P P + S L P
Sbjct: 1004 S--PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP--PALPLSVPSPLSPIG 1059
Query: 695 PETGVS---RLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLR 751
GVS LH E +VS E P S P P G P P +
Sbjct: 1060 KVVGVSDEAELH-EMETEKVS--EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
Query: 752 -----PEPLE-TRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEP-- 803
PL+ +PEP +T S L EL + S + L+P + V+ + + P
Sbjct: 1117 GLGEDTAPLDGIDAPGSQPEPGQTPGS-LASEL---KGSPVLLDPEELAPVTPMEVYPEC 1172
Query: 804 PKTGRVSSLCPE 815
+T S C E
Sbjct: 1173 KQTAGQGSPCEE 1184
Score = 95.1 bits (235), Expect = 3e-19
Identities = 174/664 (26%), Positives = 232/664 (34%), Gaps = 91/664 (13%)
Query: 105 SKLSPAQPARKAFVEEVEAQLMT---KHPLAMYPNLGEDMPPDLLLQVL-----KPLDPE 156
S +SP A + F E+ L + PL+ P PP + P+ P
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
Query: 157 RKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPE 216
++ + + P E P E SP P S L P P +P S P P +
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS---PPPED 704
Query: 217 TGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEP---PKTQVSSLHLEPPETGVSHLYLE 273
+ S PP+ + SL LE E+ + L EP P+++ L P E +S E
Sbjct: 705 SPAS----PPPEDSLMSLPLE--ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
Query: 274 PPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPE 333
P HL P+ + +S EP VP+ P++ HL P+P E HL P+
Sbjct: 759 P------HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL---HLSPQ 809
Query: 334 PPKTLVSSLHPEP---PETGVSHLCPEPPETRVSPLRQ---LPPEAGVSHLCPEPPKTRV 387
+ +S + EP P+ SHL P+ E +SP + L PE L P P K
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK--- 866
Query: 388 PPLRP-ETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPP--E 444
PP P + P PLFP P + +S L EP EP + S L E P
Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP-------ALSEPGEPPLSPLPEELPLSP 919
Query: 445 TGVSHLRPE--PPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEP 502
+G L P+ PP L PP + + P + L E P PE
Sbjct: 920 SGEPSLSPQLMPPDP------LPPPLSPIITAAAPPALSPLGEL--EYPFGAKGDSDPES 971
Query: 503 PKTRVSHLRP--EPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRP 560
P P P E + P PP IL P S S + P P + P
Sbjct: 972 PLAAPILETPISPPPEANCTDPEPVPPMIL--------PPSPGSPVGPASPIL----MEP 1019
Query: 561 EPPKTRMYSLRPEPPDTGVSHLCPEP--PKTRVSSLPPEPPETGVSHLCP--EPPETRVS 616
PP+ P C P P + S L P GVS E +VS
Sbjct: 1020 LPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079
Query: 617 HLRPEPPETGVSHLRPEPPKTRMYSL---RPEPPNTGVSHLCPEPPKTRVSSLPPEPPET 673
PE P S P P S P P S L + P PE
Sbjct: 1080 --EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
Query: 674 G------VSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLC 727
G S L P L P P ++PE +T E E + +
Sbjct: 1138 GQTPGSLASELKGSPVLLDPEELAPVTP----MEVYPECKQTAGQGSPCEEQEEPRAPVA 1193
Query: 728 PEPP 731
P PP
Sbjct: 1194 PTPP 1197
Score = 61.6 bits (148), Expect = 4e-09
Identities = 145/559 (25%), Positives = 191/559 (34%), Gaps = 118/559 (21%)
Query: 108 SPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDA-GSCE 166
SP PA + A K P P G D P +L L++ + + +D G
Sbjct: 2128 SPTTPAGLS----TSADGFLKPPAGSVP--GPDSPGELFLKLPPQVPAQVPSQDPFGLAP 2181
Query: 167 GQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQ- 225
PT P YP P P T P +PP SS RP + G H P
Sbjct: 2182 AYPLEPRFPTAPPTYP-----PYPSPTGA---PAQPPMLGASS-RPGAGQPGEFHTTPPG 2232
Query: 226 PPKTQVSSLH--LEPPETGVSHLR-PEPPKT---QVSSLHLEPPETGVSHLYLEPPGTGV 279
P+ Q S+ L+P + +L PE P + S L PP G S LE +
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292
Query: 280 SHLCPE--PPK-----TRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHP 332
P PP + S H E PD+ P R S + P+ G+ P
Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352
Query: 333 EPPKTLVSS--LHPEPPETGVSHLCP--EPPETRVSPLRQLPPEAGVSHL----CPEPPK 384
P + L S HP+ G S+ P +PP ++P Q PP L P P
Sbjct: 2353 PPAQALAPSPPSHPDIFRPG-SYTDPYAQPP---LTPRPQPPPPESCCALPPRSLPSDPF 2408
Query: 385 TRVPPLRPETPKNGVSPLFPEP------------PKTRISNLRSEPPKIGVSHLCLEPPK 432
+RV P P++ + SPL P P P+ + + S PP S +P
Sbjct: 2409 SRV-PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR---DPFA 2464
Query: 433 TRGSHLRPEPPET------------GVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
RP+PPE G P LH + P +PP
Sbjct: 2465 PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS-------GQPPN 2517
Query: 481 KDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE 540
S P TG P P + EPS L+P P+ + PP
Sbjct: 2518 FVRS------PGTGAFVGTPSPMRFTFPQAVGEPS------LKPPVPQPGL-----PPPH 2560
Query: 541 SSVSHLRPEPP-----------ETGVSHLRPEPPKTRMYSLRPEPPDTGVSH-LCP-EPP 587
SH P P TG H P L P TG S+ L P PP
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSP-------LGPSSGSTGESYGLSPLRPP 2613
Query: 588 KTRVSSLPPEPPETGVSHL 606
S LPP P+ + +L
Sbjct: 2614 ----SVLPPPAPDGSLPYL 2628
Score = 52.0 bits (123), Expect = 3e-06
Identities = 89/350 (25%), Positives = 124/350 (35%), Gaps = 61/350 (17%)
Query: 464 LEPPETGVSHLCPEPPEKDVSHLRPEPPDT-------GVSHLCPEPPK--TRVSHLRPEP 514
L+PP V P+ P + L P+ P G++ P P+ T P P
Sbjct: 2143 LKPPAGSVPG--PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYP 2200
Query: 515 SETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEP 574
S TG +PP + SS RP + G H P P T + +P
Sbjct: 2201 SPTGAP---AQPPMLGASS-------------RPGAGQPGEFHTTP--PGTPRH--QPST 2240
Query: 575 PDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP 634
PD + CP V PE P G + S PP G S E
Sbjct: 2241 PDPFLKPRCPSLDNLAV----PESPGVGGG---------KASEPLLSPPPFGESRKALEV 2287
Query: 635 PKTRMYSLRPE--PPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRP 692
K + + P PPN G + T + L + P+ + L P R S + P
Sbjct: 2288 KKEELGASSPSYGPPNLGF--VDSPSSGTHLGGLELKTPDVFKAPLTP-----RASQVEP 2340
Query: 693 EPPETGVSRLHPEPPKTRVSSLHAEPPESRV-SHLCP--EPPETGVSHLRPEPPKPR-VS 748
+ P G+ P P + S + P R S+ P +PP T RP+PP P
Sbjct: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP----RPQPPPPESCC 2396
Query: 749 SLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS 798
+L P L + P P++ S P P+P + P T R S
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
Score = 40.8 bits (94), Expect = 0.007
Identities = 77/315 (24%), Positives = 114/315 (36%), Gaps = 51/315 (16%)
Query: 200 PEPPKT-PVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
P+PPK PV P G+ Q + Q+ + + P+ + HL P+ + Q+ +L
Sbjct: 4170 PQPPKPGPVLQSGQGLPGVGIMPTVGQL-RAQLQGVLAKNPQ--LRHLSPQQQQ-QLQAL 4225
Query: 259 HLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHR----EPPETGVPDLCLEPPKSR 314
++ + PP + P T+ S L +P G P P
Sbjct: 4226 LMQRQLQQSQAVRQTPPY--------QEPGTQTSPLQGLLGCQPQLGGFPG----PQTGP 4273
Query: 315 VSHLRPEPSETGVSHLHPEPPKTL-----VSSLHPEPPETGVSHLCPEPPETRVSPLRQL 369
+ L P G L P PP L + +HP PP + P+ P SP QL
Sbjct: 4274 LQELGAGPRPQGPPRL-PAPPGALSTGPVLGPVHPTPPPSSPQE--PKRPSQLPSPSSQL 4330
Query: 370 PPEAGVSHLCPEPPKTRVPPLRPETPKNGVSP--------LFP------EPPKTRISNLR 415
P EA + P PK + P L P P VSP LF +PP +
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEP--PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 416 SEPPKIGVSHL----CLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGV 471
E + HL P+ ++ EP E + L + K + + P T
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCA-LGAQSVKREANGEPIGAPGTS- 4446
Query: 472 SHLCPEPPEKDVSHL 486
+HL P + HL
Sbjct: 4447 NHLLLAGPRSEAGHL 4461
Score = 37.0 bits (84), Expect = 0.096
Identities = 102/403 (25%), Positives = 146/403 (36%), Gaps = 89/403 (22%)
Query: 205 TPVSSLRPEPPE-----TGVSHL---RPQPPKTQVSSLHLEPPETGVSHLR-PEPPKTQV 255
T S+ EP E +G S L +PQP + Q SSL L+PP LR P + QV
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQP-QPQPSSLQLQPP------LRLPGQQQQQV 4105
Query: 256 SSLHL-------------EPPETGVSHLYLEP-------PGTGVSHLC-PEPP---KTRV 291
S LH + V HL +P PG+ +L P+ P +
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165
Query: 292 SHLHREPPE--------TGVPDLCLEPPKSRVSHLRPE-----PSETGVSHLHPEPPKTL 338
++ +PP+ G+P + + P V LR + + HL P+ + L
Sbjct: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMP---TVGQLRAQLQGVLAKNPQLRHLSPQQQQQL 4222
Query: 339 VSSLHPE--PPETGVSHLCP-EPPETRVSPLRQL----PPEAGVSHLCPEPPKTRVPPLR 391
+ L V P + P T+ SPL+ L P G P + R
Sbjct: 4223 QALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPR 4282
Query: 392 PETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLR 451
P+ P P P PP S P +G H P S P+ P S
Sbjct: 4283 PQGP-----PRLPAPP-----GALSTGPVLGPVH----PTPPPSSPQEPKRPSQLPSPSS 4328
Query: 452 PEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSH-LCP-EPPKTRVSH 509
P + ++ H P+ L EPP VS + DT S L P +PP
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTL--EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET 4386
Query: 510 LRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPE 552
+PE S HL +++ PE+S ++ EP E
Sbjct: 4387 QKPEQSSLVPGHLDQVNGQVV--------PEASQLSIKQEPRE 4421
Score = 35.0 bits (79), Expect = 0.37
Identities = 49/177 (27%), Positives = 62/177 (35%), Gaps = 36/177 (20%)
Query: 609 EPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPP 668
E P + L + P+TG L+ Y+L+ + +S L E P P
Sbjct: 4836 EGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI--LSLLKQESPA-------P 4886
Query: 669 EPPET-----GVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRV 723
EPP VS+L V L PPE P PP + ++ A PP +
Sbjct: 4887 EPPTQHSYTYNVSNL-------DVRQLSAPPPE------EPSPPPSPLAPSPASPPTEPL 4933
Query: 724 SHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPK 780
L EP EPP P L P R R PPE G P L K
Sbjct: 4934 VELPTEP--------LAEPPVPSPLPLASSPESARPKP-RARPPEEGEDSRPPRLKK 4981
Score = 30.4 bits (67), Expect = 9.0
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 6/64 (9%)
Query: 731 PETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEP 790
P G H P P P+ RP L + S L P E + HP PKP+ + LEP
Sbjct: 4300 PVLGPVHPTPPPSSPQEPK-RPSQLPSPSSQL---PTEAQLPPTHPGTPKPQGPT--LEP 4353
Query: 791 PKTR 794
P R
Sbjct: 4354 PPGR 4357
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 130 bits (326), Expect = 8e-30
Identities = 184/702 (26%), Positives = 252/702 (35%), Gaps = 93/702 (13%)
Query: 151 KPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSL 210
KP D E +LEDA + E Q ++ P + E E + + + + + + L
Sbjct: 630 KPPDEEHRLEDAET-ESQSAVSETPQKRSDAVQKEVVDMKSEGQATVI--QQLEQTIEDL 686
Query: 211 RPEPPETGVSHLRPQPPK--TQVSSLHLEPPETGVSH--------LRPEPPKT------Q 254
R T ++ L Q P T+V+S H + E GV+ LR E + +
Sbjct: 687 R-----TKIAELERQYPALDTEVASGH-QGLENGVTASGDVCLEALRLEEKEVRHHRILE 740
Query: 255 VSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGV--------PDL 306
S+ P E G + PP G+ P PP + E + L
Sbjct: 741 AKSIQTSPTEEG--GVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQL 798
Query: 307 CLEPPKSRVSHLRPEPS---ETGVSHLHPEPPKTLVSSL---HPEPPETGVSHLC--PEP 358
P +S P PS G +PP ++ + H + + C P P
Sbjct: 799 DSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP 858
Query: 359 PETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEP 418
P + P G + P PP PPL T S P+PP + + + P
Sbjct: 859 PPLPCTESSSSMPGLG---MVPPPP----PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPP 911
Query: 419 PKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEP 478
P PP G+ + P PP G P PP +++ PP G P P
Sbjct: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGI--PPPPPLPGAAIPPPPPLPGAG--IPLP 967
Query: 479 PEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAP 538
P + + P PP G P PP + + P P G P PP + + + P
Sbjct: 968 PPLPGAGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPPP 1023
Query: 539 PESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP 598
P + P PP G P PP + P PP G P PP + +PP P
Sbjct: 1024 PLPGAG-IPPPPPLPGAGI--PPPPPLPGAGIPPPPPLPGAG--IPPPPPLPGAGIPPPP 1078
Query: 599 PETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEP 658
P G P PP + + P PP GV + P PP P G+ P P
Sbjct: 1079 PLPGAG--IPPPPPLPGAGIPPPPPLPGVG-IPPPPPL----------PGAGI----PPP 1121
Query: 659 PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEP 718
P + +PP PP G + P PP RV + P PP G P PP + + P
Sbjct: 1122 PPLPGAGIPPPPPLPGAG-IPPPPPLPRVG-IPPPPPLPGAGI--PPPPPLPGAGIPPPP 1177
Query: 719 PESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPEL 778
P V + P PP GV + P PP P P PL P PP P
Sbjct: 1178 PLPGVG-IPPPPPLPGVG-IPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Query: 779 PKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTG 820
P VS PP +V S L P +V P P +G
Sbjct: 1236 PLLPVSG----PPLLPQVGSSTLPTP---QVCGFLPPPLPSG 1270
Score = 105 bits (262), Expect = 2e-22
Identities = 127/444 (28%), Positives = 163/444 (36%), Gaps = 73/444 (16%)
Query: 188 PRPPETR-VSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHL 246
P+PP + LPP PP P + + P PP G L P PP + + PP
Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL-PLPP---LPGAGIPPPPPLPGAA 952
Query: 247 RPEPPKTQVSSLHLEPPETGVSHLYLEP-PGTGVSHLCPEPPKTRVSHLHREPPETGVPD 305
P PP + + L PP G P PG G+ P PP P G+P
Sbjct: 953 IPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGI----PPPPPL---------PGAGIP- 998
Query: 306 LCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSP 365
PP + + P P G P PP + + P PP G P PP +
Sbjct: 999 ---PPPPLPGAGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPGAG 1051
Query: 366 LRQLPPEAGVSHLCPEP-PKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVS 424
+ PP G P P P +PP P P G+ P PP + + PP GV
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGI----PPPPPLPGAGIPPPPPLPGVG 1106
Query: 425 HLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVS 484
PP G+ + P PP G + P PP P G+ P PP
Sbjct: 1107 --IPPPPPLPGAGIPPPPPLPGAG-IPPPPPL----------PGAGI----PPPPPLPRV 1149
Query: 485 HLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVS 544
+ P PP G P PP + + P P GV P PP + + PP
Sbjct: 1150 GIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGVG--IPPPPPLPGVGIPPPPPLPGAG 1205
Query: 545 HLRPEPPETGVS-HLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGV 603
+ P PP G+ P PP PP TG+ P PP VS PP P+ G
Sbjct: 1206 -IPPPPPLPGMGIPPAPAPPL--------PPPGTGI----PPPPLLPVSG-PPLLPQVGS 1251
Query: 604 SHLCPEPPETRVSHLRPEPPETGV 627
S L P +V P P +G+
Sbjct: 1252 STL----PTPQVCGFLPPPLPSGL 1271
Score = 77.0 bits (188), Expect = 8e-14
Identities = 89/334 (26%), Positives = 118/334 (35%), Gaps = 35/334 (10%)
Query: 503 PKTRVSHLRPEPS---ETGVSHLRPEPPKILVSSLHQAPPESSVSHLR------PEPPET 553
P +S P PS G +PP +S+ Q E SVS P PP
Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHS-ISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
Query: 554 GVSHLRPEPPKTRMYSLRPEPPDTGV------SHLCPEPPKTRVSSLPPEPPETGVSHLC 607
+ P M P PP G+ S P+PP + + + P PP
Sbjct: 862 PCTESSSSMPGLGMVP-PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
Query: 608 PEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLP 667
P PP + + P PP G P PP ++ P PP G P PP + +P
Sbjct: 921 PPPPPLPGAGILPLPPLPGAG--IPPPPPLPGAAIPPPPPLPGAG--IPLPPPLPGAGIP 976
Query: 668 PEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLC 727
P PP G P PP + + P PP G + P PP + PP
Sbjct: 977 PPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAG-IPPPPP---LPGAGIPPPPPLPGAGI 1030
Query: 728 PEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLH 787
P PP + + P PP P P PL + + P PP G P P +
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAG----IPPPPPLPGAG 1084
Query: 788 LEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGA 821
+ PP + + PP G + P P GA
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPG--VGIPPPPPLPGA 1116
>gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]
Length = 632
Score = 127 bits (319), Expect = 5e-29
Identities = 127/431 (29%), Positives = 168/431 (38%), Gaps = 15/431 (3%)
Query: 344 PEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLF 403
P P G + P E + R P AG EPP + PP +
Sbjct: 139 PRGPRAGGAQGPSGPSELPAAQGRLAPDSAGEGAPGREPPASPAPPGKEH---------- 188
Query: 404 PEPPKTRISNLRSEP-PKIGVSHLCL--EPPKTRGSHLRPEPPETGVSHLRPEPPKTRVS 460
P K I + S P P G+ CL E R + P+ +S P + +
Sbjct: 189 PRDLKFSIDYILSSPDPFPGLKPPCLAQEGRYPRLEKVSPQCQRQTLSKRGLPTPVSILI 248
Query: 461 SLHLEPPETGVSHLCPEPPEKDVSHLRPE-PPDTGVSHLCPEPPKTRVSHLR-PEPSETG 518
+ ++ + GV+ D + PP V P R S P+ T
Sbjct: 249 NSQIQGHQQGVTGQAVVSRPLDAGWPWMDGPPLQAVFAPAPNHTLQRPSEQTCPQDLHTR 308
Query: 519 VSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTG 578
S P+ P S P + S P+ P T S P+ P TR P+ P T
Sbjct: 309 GSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDPHTR 368
Query: 579 VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTR 638
S P+ P TR S P+ P T S P+ P TR S P+ P T S P+ P TR
Sbjct: 369 GSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTR 428
Query: 639 MYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETG 698
P+ P+T S P+ P TR S P+ P T S CP+ P TR S P+ P T
Sbjct: 429 GSLSSPQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSSPQDPHTR 488
Query: 699 VSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETR 758
S P+ P TR S + P +R S CP+ P T S P+ P R S P+ L TR
Sbjct: 489 GSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDLHTR 548
Query: 759 VSHLRPEPPET 769
S P+ P T
Sbjct: 549 GSLSSPKDPHT 559
Score = 115 bits (287), Expect = 3e-25
Identities = 88/252 (34%), Positives = 112/252 (44%)
Query: 560 PEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLR 619
P+ TR P+ P T S P+ P TR S P+ P T S CP+ P TR S
Sbjct: 302 PQDLHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSS 361
Query: 620 PEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLC 679
P+ P T S P+ P TR P+ P+T S P+ P TR S P+ P T S
Sbjct: 362 PQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSS 421
Query: 680 PEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLR 739
P+ P TR S P+ P T S P+ P TR S + P +R S CP+ P T S
Sbjct: 422 PKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSS 481
Query: 740 PEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSL 799
P+ P R S P+ TR S P+ P T S P+ P R S + P TR S
Sbjct: 482 PQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSS 541
Query: 800 RLEPPKTGRVSS 811
+ G +SS
Sbjct: 542 PQDLHTRGSLSS 553
Score = 112 bits (280), Expect = 2e-24
Identities = 90/267 (33%), Positives = 115/267 (43%)
Query: 548 PEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLC 607
P+ T S P+ P TR P+ P T S CP+ P TR S P+ P T S
Sbjct: 302 PQDLHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSS 361
Query: 608 PEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLP 667
P+ P TR S P+ P T S P+ P TR P+ P+T S P+ P TR S
Sbjct: 362 PQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSS 421
Query: 668 PEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLC 727
P+ P T S P+ P TR S P+ P T S P+ P TR S + P +R S
Sbjct: 422 PKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSS 481
Query: 728 PEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLH 787
P+ P T S P+ P R S P+ TR S P+ P T S P+ P R S
Sbjct: 482 PQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSS 541
Query: 788 LEPPKTRRVSSLRLEPPKTGRVSSLCP 814
+ TR S +P R + P
Sbjct: 542 PQDLHTRGSLSSPKDPHTPPRSPLVAP 568
Score = 111 bits (278), Expect = 3e-24
Identities = 119/422 (28%), Positives = 167/422 (39%), Gaps = 27/422 (6%)
Query: 431 PKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKD-------- 482
P+ G+ P E + R P + EPP + P PP K+
Sbjct: 142 PRAGGAQGPSGPSELPAAQGRLAPDSAGEGAPGREPPAS------PAPPGKEHPRDLKFS 195
Query: 483 VSHLRPEP-PDTGVSHLC--PEPPKTRVSHLRPEPSETGVSHLR-PEPPKILVSSLHQAP 538
+ ++ P P G+ C E R+ + P+ +S P P IL++S Q
Sbjct: 196 IDYILSSPDPFPGLKPPCLAQEGRYPRLEKVSPQCQRQTLSKRGLPTPVSILINSQIQGH 255
Query: 539 PESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDT---GVSHLCPEPPKTRVSSLP 595
+ P PP +++ P P T CP+ TR S
Sbjct: 256 QQGVTGQAVVSRPLDAGWPWMDGPPLQAVFA--PAPNHTLQRPSEQTCPQDLHTRGSLSS 313
Query: 596 PEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLC 655
P+ P T S P+ P TR S P+ P T S P+ P TR P+ P+T S
Sbjct: 314 PQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDPHTRGSLSS 373
Query: 656 PEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLH 715
P+ P TR S P+ P T S P+ P TR S P+ P T S P+ P TR S
Sbjct: 374 PQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSS 433
Query: 716 AEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLH 775
+ P +R S P+ P T S P+ P R S P+ TR S P+ P T S
Sbjct: 434 PQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSSPQDPHTRGSLSS 493
Query: 776 PELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEP--TKTGASHLKELFQEGTS 833
P+ P R S + P TR S +P G +S CP+ T+ S ++L G+
Sbjct: 494 PKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLS--CPQDPHTRGSLSSPQDLHTRGSL 551
Query: 834 ST 835
S+
Sbjct: 552 SS 553
Score = 99.4 bits (246), Expect = 2e-20
Identities = 96/322 (29%), Positives = 122/322 (37%), Gaps = 51/322 (15%)
Query: 304 PDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRV 363
P+ L+ P + P+ T S P+ P T S P+ P T S CP+ P TR
Sbjct: 289 PNHTLQRPSEQTC---PQDLHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRG 345
Query: 364 SPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGV 423
S CP+ P TR P+ P S P+ P TR S + P
Sbjct: 346 SLS------------CPQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRG 393
Query: 424 SHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDV 483
S + P TRGS P+ P T S P+ P TR S + P T S P+ P
Sbjct: 394 SLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRG 453
Query: 484 SHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSV 543
S P+ P T S CP+ P TR S +SS
Sbjct: 454 SLSSPKDPHTRRSLSCPQDPHTRGS----------------------LSS---------- 481
Query: 544 SHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGV 603
P+ P T S P+ P TR P+ P T S CP+ P TR S P+ P T
Sbjct: 482 ----PQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRG 537
Query: 604 SHLCPEPPETRVSHLRPEPPET 625
S P+ TR S P+ P T
Sbjct: 538 SLSSPQDLHTRGSLSSPKDPHT 559
Score = 91.7 bits (226), Expect = 3e-18
Identities = 78/244 (31%), Positives = 99/244 (40%)
Query: 284 PEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLH 343
P+ P TR S + P T C + P +R S P+ T S P+ P T S
Sbjct: 314 PQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDPHTRGSLSS 373
Query: 344 PEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLF 403
P+ P T S P+ P TR S P S P+ P TR P+ P S
Sbjct: 374 PQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSS 433
Query: 404 PEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLH 463
P+ P TR S + P S + P TR S P+ P T S P+ P TR S
Sbjct: 434 PQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSSPQDPHTRGSLSS 493
Query: 464 LEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLR 523
+ P T S CP+ P S P+ P T S CP+ P TR S P+ T S
Sbjct: 494 PKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDLHTRGSLSS 553
Query: 524 PEPP 527
P+ P
Sbjct: 554 PKDP 557
Score = 87.4 bits (215), Expect = 6e-17
Identities = 85/283 (30%), Positives = 111/283 (39%), Gaps = 12/283 (4%)
Query: 175 PTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSL 234
P + P + P+ TR S P+ P T S P+ P T S PQ P T+ S
Sbjct: 289 PNHTLQRPSEQTCPQDLHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLS 348
Query: 235 HLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHL 294
+ P T S P+ P T+ S + P T S + P T S P+ P TR S
Sbjct: 349 CPQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLS 408
Query: 295 HREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHL 354
+ P T + P +R S P+ T S P+ P T S P+ P T S
Sbjct: 409 SPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLS 468
Query: 355 CPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNL 414
CP+ P TR S P+ P TR P+ P S P+ P TR S
Sbjct: 469 CPQDPHTR------------GSLSSPQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLS 516
Query: 415 RSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKT 457
+ P S C + P TRGS P+ T S P+ P T
Sbjct: 517 CPQDPHTRGSLSCPQDPHTRGSLSSPQDLHTRGSLSSPKDPHT 559
Score = 79.0 bits (193), Expect = 2e-14
Identities = 78/274 (28%), Positives = 102/274 (37%), Gaps = 24/274 (8%)
Query: 136 NLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRV 195
+L P + P DP + G +P G C P+ P TR
Sbjct: 310 SLSSPQDPHTRGSLSSPKDPHTR--------GSLSCPQDPHTRGSLSC----PQDPHTRG 357
Query: 196 SCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQV 255
S P+ P T S P+ P T S PQ P T+ S + P T S P+ P T+
Sbjct: 358 SLSSPQDPHTRGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRG 417
Query: 256 SSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRV 315
S + P T S + P T S P+ P TR S + P T C + P +R
Sbjct: 418 SLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRG 477
Query: 316 SHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGV 375
S P+ T S P+ P T S P+ P T S CP+ P TR
Sbjct: 478 SLSSPQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTR------------G 525
Query: 376 SHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKT 409
S CP+ P TR P+ S P+ P T
Sbjct: 526 SLSCPQDPHTRGSLSSPQDLHTRGSLSSPKDPHT 559
Score = 34.3 bits (77), Expect = 0.62
Identities = 26/76 (34%), Positives = 33/76 (43%)
Query: 187 SPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHL 246
SP+ P TR S P+ P T S P+ P T S PQ P T+ S + T S
Sbjct: 493 SPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDLHTRGSLS 552
Query: 247 RPEPPKTQVSSLHLEP 262
P+ P T S + P
Sbjct: 553 SPKDPHTPPRSPLVAP 568
>gi|211971092 hypothetical protein LOC100129583 [Homo sapiens]
Length = 393
Score = 123 bits (309), Expect = 8e-28
Identities = 82/179 (45%), Positives = 108/179 (60%), Gaps = 7/179 (3%)
Query: 1 MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPP-VDTQNWVFVTEGMDDFR 59
M D+R + RP + C S+ F K K+ L+FP + ++ VF +G+DDFR
Sbjct: 1 MADRRRRLRPGTLAPVREGVNCR---SRCFTKHKNG-LKFPTSLHSRQLVFPRKGLDDFR 56
Query: 60 YGCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVE 119
GC + E LP+I R PQ PK R+ KLLK+A + SKLSPAQ ARKAF+E
Sbjct: 57 KGCPPCTGLVTQVPVEGFLPQIYHRAPQLAPKKRQIKLLKEADVLSKLSPAQQARKAFLE 116
Query: 120 EVEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGS-CEGQEKTTDEPTE 177
+VEA L T HPLA+Y NL E MP +LL +VL+ LDP+RKLED + C+ K EPT+
Sbjct: 117 DVEAHL-TPHPLALYLNLEEAMPIELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTK 174
Score = 106 bits (264), Expect = 1e-22
Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 10/164 (6%)
Query: 863 VNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYSMELDEMDEVKFFSQEKDLDGKI 922
++EE I FD E + ++ K N+ LK S+ L ++ E +FF Q+ + K+
Sbjct: 228 IDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFF-QKLGYERKL 286
Query: 923 QNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDPKL---------VLEKPDEPDIL 973
Q N + + VKM YGAWYL PKL KK R DEPL+DP++ E ++ ++L
Sbjct: 287 QKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELL 346
Query: 974 DGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQR 1017
L+G +AFKDFILS+GY P ++ ++ + KTPI+R
Sbjct: 347 ADLHGTVAFKDFILSRGYRTPRFLENMYIGKECKRACNKTPIKR 390
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 111 bits (278), Expect = 3e-24
Identities = 181/695 (26%), Positives = 252/695 (36%), Gaps = 117/695 (16%)
Query: 86 PQADPKSRKKKLLKKAALFSKLSPAQPARKAF-----VEEVEAQLMTKHPLAMYPNLGED 140
P+ P + L K + K P PA+K V E +++ + + + P +
Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547
Query: 141 MPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPP 200
+PP + +V K PE+K+ +A + + + P P + PE +V PP
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV--------VPEKKVPAAPP 10599
Query: 201 EPPK-TPVSSLRPEPPETGVSHLR-PQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
+ P+ TPV PE P+ V + P PP + E P T V PE PK V
Sbjct: 10600 KKPEVTPVKV--PEAPKEVVPEKKVPVPPPKKP-----EVPPTKV----PEVPKVAVPEK 10648
Query: 259 HL-----EPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKS 313
+ PE+ ++ EP + EPP V E PE P PPK
Sbjct: 10649 KVPEAIPPKPESPPPEVFEEPEEVALE----EPPAEVV-----EEPEPAAPPQVTVPPKK 10699
Query: 314 RVSHLRPEPSETGVSHLHPEPPKTLVSSLHPE-PPETGVSHLCPEPPETRVSPLRQLPPE 372
V PE V PE P V + E PE V + P+ PE + + ++P E
Sbjct: 10700 PV----PEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE 10755
Query: 373 AGVSHLCPEPPKTRVPPLR-PETPKNGVSPLFPEPPKTRI-SNLRSEPPKIGVSHLCLEP 430
P K VPP + PE PK P+ E P + S PP++ E
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPK---KPVLEEKPAVPVPERAESPPPEV------YEE 10806
Query: 431 PKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEP----PEKDVSHL 486
P+ + PE + PE K V E PE + EP PEK V +
Sbjct: 10807 PE----EIAPE------EEIAPEEEKP-VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVI 10855
Query: 487 -RPEPPDTGVSHLCPEPPKTRVSHLRPEPSET-GVSHLRPEPPKILVSSLHQAPPESSVS 544
+PE P PPK PEP + L+P PP APP+ V
Sbjct: 10856 KKPEAP----------PPK------EPEPEKVIEKPKLKPRPP-----PPPPAPPKEDVK 10894
Query: 545 H---LRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPET 601
P+ V P K + L+ + V L PE PEP E
Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPE--------RKPEPKEE 10946
Query: 602 GV-SHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPK 660
V + + PE + P+ E PEPP + P T PEP
Sbjct: 10947 VVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEP-- 11004
Query: 661 TRVSSLPPEPPETGVSHLCPEP---PETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAE 717
T+V + P P PEP PE V ++P P E + + P V AE
Sbjct: 11005 TKVPEIKPAIPLP-----APEPKPKPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAE 11058
Query: 718 PPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRP 752
+ P+ P GV P P + LRP
Sbjct: 11059 AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRP 11093
Score = 106 bits (264), Expect = 1e-22
Identities = 186/697 (26%), Positives = 249/697 (35%), Gaps = 153/697 (21%)
Query: 188 PRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLR 247
P+ PE +PP+ P T V R EPP P+ PK V + PE
Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVP-RKEPPAKV-----PEVPKKIVVEEKVRVPE------E 10487
Query: 248 PEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREP-PETGVPDL 306
P P T+V + L P E PP PE P +V +E PE VP
Sbjct: 10488 PRVPPTKVPEV-LPPKEVVPEKKVPVPPAKK-----PEAPPPKVPEAPKEVVPEKKVP-- 10539
Query: 307 CLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPL 366
+ PPK +PE T V PE PK V PE V P PE+ +
Sbjct: 10540 -VPPPK------KPEVPPTKV----PEVPKAAV-------PEKKVPEAIPPKPESPPPEV 10581
Query: 367 RQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPL-FPEPPKTRISNLRSEPPKIGVSH 425
+ P E + PE PP +PE V+P+ PE PK + + P
Sbjct: 10582 PEAPKE-----VVPEKKVPAAPPKKPE-----VTPVKVPEAPKEVVPEKKVPVP------ 10625
Query: 426 LCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSH 485
PPK +PE P T V PE PK V PE V P PE
Sbjct: 10626 ----PPK------KPEVPPTKV----PEVPKVAV-------PEKKVPEAIPPKPESPPPE 10664
Query: 486 LRPEPPDTGVSHLCPE---------PPKTRVSHLRPEPSETG--VSHLRPEPPKILVSSL 534
+ EP + + E PP+ V +P P + V +PE P + V +
Sbjct: 10665 VFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEV 10724
Query: 535 -HQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLR---PEPPDTGVSHLCPEPPKT- 589
+ PE V + P+ PE + + PE PK + + P+ P+ + + PE PK
Sbjct: 10725 PKEVVPEKKVPLVVPKKPEAPPAKV-PEVPKEVVPEKKVAVPKKPEVPPAKV-PEVPKKP 10782
Query: 590 ------------RVSSLPPE----PPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPE 633
R S PPE P E E V E PE + E
Sbjct: 10783 VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842
Query: 634 P----PKTRMYSLR-PE--PPNTGVSHLCPEPPKT--RVSSLPPEPPETGVSHLC----- 679
P P+ ++ ++ PE PP E PK R PP PP+ V
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKA 10902
Query: 680 ------PEPPET----RVSHLRPEPPETGVSRLHPE---PPKTRV--SSLHAEPPESRVS 724
PE P+ ++ L+ E V +L PE PK V S+ + PE
Sbjct: 10903 IPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEP 10962
Query: 725 HLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVS 784
+ P+ E PEPP P+ P T+ PEP T V + P +P P
Sbjct: 10963 KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEP--TKVPEIKPAIPLPAP- 11019
Query: 785 SLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGA 821
EP ++PP PEPT A
Sbjct: 11020 ----EPKPKPEAEVKTIKPPPVE------PEPTPIAA 11046
Score = 83.6 bits (205), Expect = 9e-16
Identities = 191/790 (24%), Positives = 276/790 (34%), Gaps = 103/790 (13%)
Query: 78 LPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNL 137
+PK P P+ KK K L K PA+ V EV + + + + +
Sbjct: 9967 VPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK---VPEVPKKPVPEEKVPVPVPK 10023
Query: 138 GEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSC 197
+ PP + +V K PE+K+ + + P P K E P P +V
Sbjct: 10024 KVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA 10083
Query: 198 LPPEPPK----TPVSSLRPEPPE-------TGVSHLRPQPPKTQVSSLHLEPPETGV--- 243
PP+ PK PV P+ E + P+ + + P E V
Sbjct: 10084 PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE 10143
Query: 244 -SHLRPEPPKTQVSSLHLEPPETGVSHLYLEP---PGTGVSHLCPE-----PPKTRVSHL 294
+ PE + ++ E V + P P V PE K V
Sbjct: 10144 EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPK 10203
Query: 295 HREPPETGVPDLCLEPPKSRV----------SHLRPEPSETGVSHLH-PEPPKTLVSSLH 343
E P VP++ + + R+ + EP E +S PE P ++
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEE 10263
Query: 344 PEPPETG--VSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSP 401
PP + PE P T V + PP A VS PE K VP + E P V
Sbjct: 10264 VAPPRVPEVIKKAVPEAP-TPVPKKVEAPP-AKVSKKIPE-EKVPVPVQKKEAPPAKV-- 10318
Query: 402 LFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSS 461
PE PK P K V P +G + E + V+ + K R
Sbjct: 10319 --PEVPKKVPEKKVLVPKKEAV-------PPAKGRTVLEE--KVSVAFRQEVVVKER--- 10364
Query: 462 LHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSH 521
L LE E V E PE++ H E + G H E K + E V
Sbjct: 10365 LELEVVEAEVE----EIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHR 10420
Query: 522 LRP--EPPKILVSSLHQAP---PESSVSHLRPEPPETGVSHLR------PEPPKTRMYSL 570
+ E ++ V +AP PE S + P+ P T V + PE PK +
Sbjct: 10421 VIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEE 10480
Query: 571 R------PEPPDTGVSHLCPEP---PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPE 621
+ P P T V + P P+ +V P + PE + P E P
Sbjct: 10481 KVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPV 10540
Query: 622 PPETGVSHLRPEPPKTRMYSLRPEPPNTGV-SHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
PP +PE P T++ PE P V PE + S PPE PE +
Sbjct: 10541 PPPK-----KPEVPPTKV----PEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVV-- 10589
Query: 681 EPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHL----CPEPPETGVS 736
PE +V P+ PE ++ PE PK V P + + PE P+ V
Sbjct: 10590 --PEKKVPAAPPKKPEVTPVKV-PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVP 10646
Query: 737 HLR-PEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRR 795
+ PE P+ S PE E EPP V P P P+V+ +P ++
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAP-PQVTVPPKKPVPEKK 10705
Query: 796 VSSLRLEPPK 805
++ + P+
Sbjct: 10706 APAVVAKKPE 10715
Score = 55.5 bits (132), Expect = 3e-07
Identities = 136/603 (22%), Positives = 206/603 (34%), Gaps = 106/603 (17%)
Query: 175 PTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLR----------- 223
PT+P P PE +V P+ K P + EP + +R
Sbjct: 9804 PTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQV 9863
Query: 224 -------PQPPKTQVSSLHLEPPETGVSH--LRPEPPKTQVSSLHLEPPETGVSHLYLEP 274
P PK V+ + P V+ PE PK LEP E
Sbjct: 9864 TEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPK------ELEPEEVAFEE----- 9912
Query: 275 PGTGVSHLCPEPPKTRVSHLHRE----PPETGVPDLCLEPPKSRVSHLRPEPSETGVSHL 330
V+H+ + ++H E E VP + ++ P+ + E V
Sbjct: 9913 --EVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKK 9970
Query: 331 HPEPPKTLVSSLHPEPPETGVSHLCP---EPPETRVSPLRQLP-PEAGVSHLCPEPPKTR 386
PP + P+ PE V L P +PP +V + + P PE V P P K
Sbjct: 9971 KEAPPAKVPEV--PKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVP--VPVPKKVE 10026
Query: 387 VPPLR-PETPKNGV-SPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPE 444
PP + PE PK V P P ++ ++ P++ P K +P P
Sbjct: 10027 APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV--------PKKLIPEEKKPTPVP 10078
Query: 445 TGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGV----SHLCP 500
V P+ PK R EP V+ P E++V P+ V + P
Sbjct: 10079 KKVEAPPPKVPKKR------EPVPVPVA----LPQEEEVLFEEEIVPEEEVLPEEEEVLP 10128
Query: 501 EPPKT--RVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSV-SHLRPE-PPETGVS 556
E + + PE E P + V + PE V ++P+ P V
Sbjct: 10129 EEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 557 HLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVS 616
++ + + ++ + E E P +V +P + E + + P+ E
Sbjct: 10189 EIKKKVTEKKVVIPKKE-----------EAPPAKVPEVPKKVEEKRI--ILPKEEEVLPV 10235
Query: 617 HLRPEPPETGVSHLR-PEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGV 675
+ EP E +S PE P + PP PE K V P P+
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRV------PEVIKKAVPEAPTPVPKK-- 10287
Query: 676 SHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPE----PP 731
E P +VS PE + V E P +V + + PE +V L P+ PP
Sbjct: 10288 ----VEAPPAKVSKKIPE-EKVPVPVQKKEAPPAKVPEVPKKVPEKKV--LVPKKEAVPP 10340
Query: 732 ETG 734
G
Sbjct: 10341 AKG 10343
Score = 39.7 bits (91), Expect = 0.015
Identities = 163/738 (22%), Positives = 254/738 (34%), Gaps = 106/738 (14%)
Query: 92 SRKKKLLK-KAALFSKLSPAQPARKAFVE-------EVEAQLMTKHPLAMYPNLGEDMPP 143
+RKK++ K K A++ K ++ F+E E+E + T+ Y ++
Sbjct: 9043 TRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYE 9102
Query: 144 DLLLQVLKPLDPE--RKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPE 201
++ ++ K + E E+ +E+ DE E + E + V E
Sbjct: 9103 EIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHE 9162
Query: 202 ---PPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
P K P P P +P K + +S +E + V+ + PE K V
Sbjct: 9163 RKVPAKVPEKKAPPPPKVIK----KPVIEKIEKTSRRMEEEKVQVTKV-PEVSKKIVPQ- 9216
Query: 259 HLEPPETGVSHLYLEPPGTGV---SHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRV 315
+P T V +E V + E SH E T VP++ E
Sbjct: 9217 --KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVT-VPEVQKEIVTEEK 9273
Query: 316 SHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGV 375
H+ + P K + P P V P+ PE P + +P E
Sbjct: 9274 IHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEV---PKKPVPEEKK- 9329
Query: 376 SHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPP-KI-GVSHLCLEPPKT 433
P P + P P+ P+ P+ E ++ + PP K+ V + K
Sbjct: 9330 ----PVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKI 9385
Query: 434 RGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPD- 492
R E P V PE PK +V P P PP+ +P P +
Sbjct: 9386 TIVTQREESPPPAV----PEIPKKKVPEERKPVPRK--EEEVPPPPKVPALPKKPVPEEK 9439
Query: 493 ----TGVSHLCPEPPKTRVSH--LRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHL 546
V+ P PP+ VS + E L P+ + + H+ E S+
Sbjct: 9440 VAVPVPVAKKAP-PPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSY- 9497
Query: 547 RPEPPETGVS--------HLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP 598
E GVS E + Y + EP + V K RV + P E
Sbjct: 9498 --SEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK-RVEAEPAEV 9554
Query: 599 PETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEP 658
E + +P ++ EPP V PE PK + PE P P
Sbjct: 9555 TERQEKKIVLKP---KIPAKIEEPPPAKV----PEAPK----KIVPEKKVP-----APVP 9598
Query: 659 PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLH---PEPPKTRVSSLH 715
K +V PP+ PE + + +V + EP V+ H + K V+
Sbjct: 9599 KKEKVP--PPKVPEEPKKPVPEKKVPPKVIKME-EPLPAKVTERHMQITQEEKVLVAVTK 9655
Query: 716 AE-PPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHL 774
E PP++RV PE P+ V P+ +V L+P+ R E P V+
Sbjct: 9656 KEAPPKARV----PEEPKRAV-------PEEKVLKLKPK---------REEEPPAKVTEF 9695
Query: 775 HPELPKPRVSSLHLEPPK 792
+ K + +E PK
Sbjct: 9696 RKRVVKE--EKVSIEAPK 9711
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 108 bits (271), Expect = 2e-23
Identities = 137/590 (23%), Positives = 182/590 (30%), Gaps = 41/590 (6%)
Query: 185 EFSPRPPETRVSCLPPEPPKTPVSSL--RPEPPETGVSHLRPQPPKTQVSSLHLEPPETG 242
E +P P+ S P EP T + S P+ P + P PK + EP T
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274
Query: 243 VSHLRP----EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREP 298
P EP T S P E + +P T P PK +EP
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPTPTTPKEP 333
Query: 299 PETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEP 358
T + PK +P+ T P PK + EP T P P
Sbjct: 334 APT-TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE--PAP 390
Query: 359 PETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLR----PETPKNGV--SPLFPEP--PKTR 410
T+ +P P + P PK P P TPK +P P P PK
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETG 470
EP PK E T L P P+ + +P T
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510
Query: 471 VSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKIL 530
L P PE+ EP T P PK EP+ T P PK
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 531 VSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTR 590
+ + +++ P P + PK + EP T P PK
Sbjct: 571 APTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTG 650
+ P EP T P P+ EP T + PK + P +T
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTT 680
Query: 651 VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTR 710
P PK + P EP T P PET P P + VS P T+
Sbjct: 681 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTTTK 730
Query: 711 VSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV---SSLRPEPLET 757
+ + P+ L EP + + EP P ++ +PE T
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
Score = 94.7 bits (234), Expect = 4e-19
Identities = 156/696 (22%), Positives = 202/696 (29%), Gaps = 77/696 (11%)
Query: 165 CEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRP 224
C+ Q K D+ + C E P+PP + + + V+ P
Sbjct: 45 CDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT--TP 102
Query: 225 QPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCP 284
TQ + + P T + P P S E T +E T ++
Sbjct: 103 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 162
Query: 285 EPP---KTRVSHLHREPPETGVPDLC-----LEPPKSRVSHLRPEPSETGVSHLHPEPPK 336
KT + + +T DL L P + P+ T P PK
Sbjct: 163 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 222
Query: 337 TLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPK 396
S+ EP T + P T P A + P P T+ P P TPK
Sbjct: 223 EPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPK 276
Query: 397 NGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRP-EPPETGVSHLRPEPP 455
P P T+ EP P T+ + P EP T P P
Sbjct: 277 E------PAPTTTK------EPA----------PTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 456 KTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRP-EPPDTGVSHLCPEPPKTRVSHLRPEP 514
K + EP T P P K+ + P EP T P PK EP
Sbjct: 315 KEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372
Query: 515 SETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEP 574
+ T P PK AP + + + P + P PK EP
Sbjct: 373 APTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------EP 418
Query: 575 PDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP 634
T P PK + P +P T P P+ EP T P
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--------EPAPTTTKKPAPTT 470
Query: 635 PKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
PK + E T L P P+ + P +P T L P PE EP
Sbjct: 471 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 530
Query: 695 PETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEP 754
T P PK + EP + EP T P PK + EP
Sbjct: 531 APTTPKAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 755 LETRVSHLRP---------EPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPK 805
T P EP T P PK + EP T P
Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646
Query: 806 TGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSD 841
T + P PT KEL T SD
Sbjct: 647 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/689 (21%), Positives = 215/689 (31%), Gaps = 75/689 (10%)
Query: 152 PLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLR 211
P +P ++ +E P +P +P P+ P EP T
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKP--------APTTPKEPAPTTPKEPAPTTTKEPS 381
Query: 212 PEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLY 271
P P+ P P T+ + + P + P PK + EP T
Sbjct: 382 PTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK--- 432
Query: 272 LEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH 331
EP T P PK +EP T PK E + T L
Sbjct: 433 -EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 332 PEPPKTLVSSLHPEPPETGVSHLCPEPPE--TRVSPLRQLP--PEAGVSHLCPEPPKTRV 387
P P+ L + +P T L P PE T +P P P+A + EP T
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 388 PPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGV 447
P TPK EP T PK EP T + +P P E
Sbjct: 552 KEPAPTTPK--------EPAPTTPKETAPTTPKGTAPTTLKEPAPT--TPKKPAPKE--- 598
Query: 448 SHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRV 507
L P K EP T P P+ EP T P PK
Sbjct: 599 --LAPTTTK--------EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648
Query: 508 SHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM 567
EP+ T + PK L + + P ++ P P+ EP T
Sbjct: 649 PTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 705
Query: 568 YSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGV 627
P P+T PP T S P E H P+ +S P P
Sbjct: 706 KKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALEN 757
Query: 628 SHLRPEPPKTRM-YSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE-PPET 685
S P P T+ + +PE T +T + P T + E E+
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 686 RVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKP 745
+++ + T P ++++L +V+ T + + E KP
Sbjct: 818 KITATTTQVTSTTTQDTTP----FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 873
Query: 746 R---VSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLE 802
+ +S P + + +P T P + KP+ + P R+++S E
Sbjct: 874 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT------PTPRKMTSTMPE 927
Query: 803 PPKTGRVS----SLCPEPTKTGASHLKEL 827
T R++ P +T S L E+
Sbjct: 928 LNPTSRIAEAMLQTTTRPNQTPNSKLVEV 956
Score = 54.3 bits (129), Expect = 6e-07
Identities = 79/338 (23%), Positives = 99/338 (29%), Gaps = 39/338 (11%)
Query: 90 PKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQV 149
PK KK A + PA K +L P + P E P +
Sbjct: 455 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEE 513
Query: 150 LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEP-PKTPVS 208
L P PE E T P EP +P P+ P EP P TP
Sbjct: 514 LAPTTPE------------EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 209 SLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP----PE 264
P ET + + P T P + L P K S+ +P P+
Sbjct: 562 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 265 TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPE--- 321
EP T P PK +EP T P K L P
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-------TPKKPAPKELAPTTTK 674
Query: 322 -PSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCP 380
P+ T P PK + EP T P PET PP +
Sbjct: 675 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPP--TTSEVS 724
Query: 381 EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEP 418
P T+ P ++P L EP + N EP
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 108 bits (271), Expect = 2e-23
Identities = 137/590 (23%), Positives = 182/590 (30%), Gaps = 41/590 (6%)
Query: 185 EFSPRPPETRVSCLPPEPPKTPVSSL--RPEPPETGVSHLRPQPPKTQVSSLHLEPPETG 242
E +P P+ S P EP T + S P+ P + P PK + EP T
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315
Query: 243 VSHLRP----EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREP 298
P EP T S P E + +P T P PK +EP
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPTPTTPKEP 374
Query: 299 PETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEP 358
T + PK +P+ T P PK + EP T P P
Sbjct: 375 APT-TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE--PAP 431
Query: 359 PETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLR----PETPKNGV--SPLFPEP--PKTR 410
T+ +P P + P PK P P TPK +P P P PK
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Query: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETG 470
EP PK E T L P P+ + +P T
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551
Query: 471 VSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKIL 530
L P PE+ EP T P PK EP+ T P PK
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 531 VSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTR 590
+ + +++ P P + PK + EP T P PK
Sbjct: 612 APTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTG 650
+ P EP T P P+ EP T + PK + P +T
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTT 721
Query: 651 VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTR 710
P PK + P EP T P PET P P + VS P T+
Sbjct: 722 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTTTK 771
Query: 711 VSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV---SSLRPEPLET 757
+ + P+ L EP + + EP P ++ +PE T
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
Score = 94.7 bits (234), Expect = 4e-19
Identities = 156/696 (22%), Positives = 202/696 (29%), Gaps = 77/696 (11%)
Query: 165 CEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRP 224
C+ Q K D+ + C E P+PP + + + V+ P
Sbjct: 86 CDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT--TP 143
Query: 225 QPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCP 284
TQ + + P T + P P S E T +E T ++
Sbjct: 144 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 203
Query: 285 EPP---KTRVSHLHREPPETGVPDLC-----LEPPKSRVSHLRPEPSETGVSHLHPEPPK 336
KT + + +T DL L P + P+ T P PK
Sbjct: 204 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 263
Query: 337 TLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPK 396
S+ EP T + P T P A + P P T+ P P TPK
Sbjct: 264 EPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPK 317
Query: 397 NGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRP-EPPETGVSHLRPEPP 455
P P T+ EP P T+ + P EP T P P
Sbjct: 318 E------PAPTTTK------EPA----------PTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 456 KTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRP-EPPDTGVSHLCPEPPKTRVSHLRPEP 514
K + EP T P P K+ + P EP T P PK EP
Sbjct: 356 KEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413
Query: 515 SETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEP 574
+ T P PK AP + + + P + P PK EP
Sbjct: 414 APTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------EP 459
Query: 575 PDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP 634
T P PK + P +P T P P+ EP T P
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--------EPAPTTTKKPAPTT 511
Query: 635 PKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
PK + E T L P P+ + P +P T L P PE EP
Sbjct: 512 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 571
Query: 695 PETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEP 754
T P PK + EP + EP T P PK + EP
Sbjct: 572 APTTPKAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 755 LETRVSHLRP---------EPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPK 805
T P EP T P PK + EP T P
Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 687
Query: 806 TGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSD 841
T + P PT KEL T SD
Sbjct: 688 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/689 (21%), Positives = 215/689 (31%), Gaps = 75/689 (10%)
Query: 152 PLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLR 211
P +P ++ +E P +P +P P+ P EP T
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKP--------APTTPKEPAPTTPKEPAPTTTKEPS 422
Query: 212 PEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLY 271
P P+ P P T+ + + P + P PK + EP T
Sbjct: 423 PTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK--- 473
Query: 272 LEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH 331
EP T P PK +EP T PK E + T L
Sbjct: 474 -EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 332 PEPPKTLVSSLHPEPPETGVSHLCPEPPE--TRVSPLRQLP--PEAGVSHLCPEPPKTRV 387
P P+ L + +P T L P PE T +P P P+A + EP T
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 388 PPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGV 447
P TPK EP T PK EP T + +P P E
Sbjct: 593 KEPAPTTPK--------EPAPTTPKETAPTTPKGTAPTTLKEPAPT--TPKKPAPKE--- 639
Query: 448 SHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRV 507
L P K EP T P P+ EP T P PK
Sbjct: 640 --LAPTTTK--------EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689
Query: 508 SHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM 567
EP+ T + PK L + + P ++ P P+ EP T
Sbjct: 690 PTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 746
Query: 568 YSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGV 627
P P+T PP T S P E H P+ +S P P
Sbjct: 747 KKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALEN 798
Query: 628 SHLRPEPPKTRM-YSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE-PPET 685
S P P T+ + +PE T +T + P T + E E+
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 686 RVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKP 745
+++ + T P ++++L +V+ T + + E KP
Sbjct: 859 KITATTTQVTSTTTQDTTP----FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 914
Query: 746 R---VSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLE 802
+ +S P + + +P T P + KP+ + P R+++S E
Sbjct: 915 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT------PTPRKMTSTMPE 968
Query: 803 PPKTGRVS----SLCPEPTKTGASHLKEL 827
T R++ P +T S L E+
Sbjct: 969 LNPTSRIAEAMLQTTTRPNQTPNSKLVEV 997
Score = 54.3 bits (129), Expect = 6e-07
Identities = 79/338 (23%), Positives = 99/338 (29%), Gaps = 39/338 (11%)
Query: 90 PKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQV 149
PK KK A + PA K +L P + P E P +
Sbjct: 496 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEE 554
Query: 150 LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEP-PKTPVS 208
L P PE E T P EP +P P+ P EP P TP
Sbjct: 555 LAPTTPE------------EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 209 SLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP----PE 264
P ET + + P T P + L P K S+ +P P+
Sbjct: 603 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 265 TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPE--- 321
EP T P PK +EP T P K L P
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-------TPKKPAPKELAPTTTK 715
Query: 322 -PSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCP 380
P+ T P PK + EP T P PET PP +
Sbjct: 716 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPP--TTSEVS 765
Query: 381 EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEP 418
P T+ P ++P L EP + N EP
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 108 bits (271), Expect = 2e-23
Identities = 137/590 (23%), Positives = 182/590 (30%), Gaps = 41/590 (6%)
Query: 185 EFSPRPPETRVSCLPPEPPKTPVSS--LRPEPPETGVSHLRPQPPKTQVSSLHLEPPETG 242
E +P P+ S P EP T + S P+ P + P PK + EP T
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 243 VSHLRP----EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREP 298
P EP T S P E + +P T P PK +EP
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPTPTTPKEP 426
Query: 299 PETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEP 358
T + PK +P+ T P PK + EP T P P
Sbjct: 427 APT-TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE--PAP 483
Query: 359 PETRVSPLRQLPPEAGVSHLCPEPPKTRVPPL----RPETPKN--GVSPLFPEP--PKTR 410
T+ +P P + P PK P P TPK +P P P PK
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Query: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETG 470
EP PK E T L P P+ + +P T
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603
Query: 471 VSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKIL 530
L P PE+ EP T P PK EP+ T P PK
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663
Query: 531 VSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTR 590
+ + +++ P P + PK + EP T P PK
Sbjct: 664 APTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTG 650
+ P EP T P P+ EP T + PK + P +T
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTT 773
Query: 651 VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTR 710
P PK + P EP T P PET P P + VS P T+
Sbjct: 774 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTTTK 823
Query: 711 VSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV---SSLRPEPLET 757
+ + P+ L EP + + EP P ++ +PE T
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
Score = 93.2 bits (230), Expect = 1e-18
Identities = 146/637 (22%), Positives = 184/637 (28%), Gaps = 75/637 (11%)
Query: 224 PQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLC 283
P TQ + + P T + P P S E T +E T ++
Sbjct: 195 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 254
Query: 284 PEPP---KTRVSHLHREPPETGVPDLC-----LEPPKSRVSHLRPEPSETGVSHLHPEPP 335
KT + + +T DL L P + P+ T P P
Sbjct: 255 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP 314
Query: 336 KTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETP 395
K S+ EP T + P T P A + P P T+ P P TP
Sbjct: 315 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTP 368
Query: 396 KNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRP-EPPETGVSHLRPEP 454
K P P T+ EP P T+ + P EP T P
Sbjct: 369 KE------PAPTTTK------EPA----------PTTTKSAPTTPKEPAPTTPKKPAPTT 406
Query: 455 PKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRP-EPPDTGVSHLCPEPPKTRVSHLRPE 513
PK + EP T P P K+ + P EP T P PK E
Sbjct: 407 PKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464
Query: 514 PSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE 573
P+ T P PK AP + + + P + P PK E
Sbjct: 465 PAPTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------E 510
Query: 574 PPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPE 633
P T P PK + P +P T P P+ EP T P
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--------EPAPTTTKKPAPT 562
Query: 634 PPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPE 693
PK + E T L P P+ + P +P T L P PE E
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 694 PPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPE 753
P T P PK + EP + EP T P PK + E
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTTPKETAPTTPKGTAPTTLKE 678
Query: 754 PLETRVSHLRP---------EPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPP 804
P T P EP T P PK + EP T P
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 805 KTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSD 841
T + P PT KEL T SD
Sbjct: 739 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775
Score = 92.0 bits (227), Expect = 3e-18
Identities = 147/667 (22%), Positives = 207/667 (31%), Gaps = 81/667 (12%)
Query: 168 QEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKT---PVSSLRPEPPETGVSHLRP 224
+E P +P E +P P+ P EP T P + EP T P
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 225 QPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCP 284
PK + EP T P PK + P T + P + P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSAP 505
Query: 285 EPPKTRVSHLHREP----PETGVPDLCLEP----PKSRVSHLRPEPSETGVSHLHPEPPK 336
PK +EP P+ P +P PK EP+ T P PK
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 337 TLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPK 396
+ E T L P PE + P L P P+ P PE P
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPA 624
Query: 397 NGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPK 456
P PK N EP PK EP T P PK
Sbjct: 625 -------PTTPKAAAPNTPKEPAP--------TTPKEPAPTTPKEPAPTTPKETAPTTPK 669
Query: 457 TRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSE 516
+ EP T P P E + + EP T P PK EP+
Sbjct: 670 GTAPTTLKEPAPTTPKK--PAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 517 TGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPD 576
T P PK + + P ++ +P P E L P K P
Sbjct: 727 TTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKE-----LAPTTTK--------GPTS 771
Query: 577 TGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPK 636
T P PK + P EP T P PET P P + VS P
Sbjct: 772 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTT 821
Query: 637 TRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPE--------TRVS 688
T+ + + P+ L EP + + P EP PE T
Sbjct: 822 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Query: 689 HLRPEPPETGVSRLHPEPPKTRVSSLHAE-PPESRVSHLCPEPPETGVSHLRPEPPKPRV 747
LR P T + P T+ ++ E ES+++ + T P ++
Sbjct: 882 DLRTTPETTTAA-----PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KI 932
Query: 748 SSLRPEPLETRVSHLRPEPPETGVSHLHPEL--PKPRVSSLHLEPPKTRRVSSLRLEPPK 805
++L+ L +V+ + T + + E PK R ++ PK ++ + +P
Sbjct: 933 TTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 992
Query: 806 TGRVSSL 812
T + ++
Sbjct: 993 TKKPKTM 999
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/689 (21%), Positives = 215/689 (31%), Gaps = 75/689 (10%)
Query: 152 PLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLR 211
P +P ++ +E P +P +P P+ P EP T
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKP--------APTTPKEPAPTTPKEPAPTTTKEPS 474
Query: 212 PEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLY 271
P P+ P P T+ + + P + P PK + EP T
Sbjct: 475 PTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK--- 525
Query: 272 LEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH 331
EP T P PK +EP T PK E + T L
Sbjct: 526 -EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 332 PEPPKTLVSSLHPEPPETGVSHLCPEPPE--TRVSPLRQLP--PEAGVSHLCPEPPKTRV 387
P P+ L + +P T L P PE T +P P P+A + EP T
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 388 PPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGV 447
P TPK EP T PK EP T + +P P E
Sbjct: 645 KEPAPTTPK--------EPAPTTPKETAPTTPKGTAPTTLKEPAPT--TPKKPAPKE--- 691
Query: 448 SHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRV 507
L P K EP T P P+ EP T P PK
Sbjct: 692 --LAPTTTK--------EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741
Query: 508 SHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM 567
EP+ T + PK L + + P ++ P P+ EP T
Sbjct: 742 PTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798
Query: 568 YSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGV 627
P P+T PP T S P E H P+ +S P P
Sbjct: 799 KKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALEN 850
Query: 628 SHLRPEPPKTRM-YSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE-PPET 685
S P P T+ + +PE T +T + P T + E E+
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910
Query: 686 RVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKP 745
+++ + T P ++++L +V+ T + + E KP
Sbjct: 911 KITATTTQVTSTTTQDTTP----FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 966
Query: 746 R---VSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLE 802
+ +S P + + +P T P + KP+ + P R+++S E
Sbjct: 967 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT------PTPRKMTSTMPE 1020
Query: 803 PPKTGRVS----SLCPEPTKTGASHLKEL 827
T R++ P +T S L E+
Sbjct: 1021 LNPTSRIAEAMLQTTTRPNQTPNSKLVEV 1049
Score = 54.3 bits (129), Expect = 6e-07
Identities = 79/338 (23%), Positives = 99/338 (29%), Gaps = 39/338 (11%)
Query: 90 PKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQV 149
PK KK A + PA K +L P + P E P +
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEE 606
Query: 150 LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEP-PKTPVS 208
L P PE E T P EP +P P+ P EP P TP
Sbjct: 607 LAPTTPE------------EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 209 SLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP----PE 264
P ET + + P T P + L P K S+ +P P+
Sbjct: 655 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 265 TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPE--- 321
EP T P PK +EP T P K L P
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-------TPKKPAPKELAPTTTK 767
Query: 322 -PSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCP 380
P+ T P PK + EP T P PET PP +
Sbjct: 768 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPP--TTSEVS 817
Query: 381 EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEP 418
P T+ P ++P L EP + N EP
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 108 bits (271), Expect = 2e-23
Identities = 137/590 (23%), Positives = 182/590 (30%), Gaps = 41/590 (6%)
Query: 185 EFSPRPPETRVSCLPPEPPKTPVSS--LRPEPPETGVSHLRPQPPKTQVSSLHLEPPETG 242
E +P P+ S P EP T + S P+ P + P PK + EP T
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 243 VSHLRP----EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREP 298
P EP T S P E + +P T P PK +EP
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPTPTTPKEP 467
Query: 299 PETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEP 358
T + PK +P+ T P PK + EP T P P
Sbjct: 468 APT-TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE--PAP 524
Query: 359 PETRVSPLRQLPPEAGVSHLCPEPPKTRVPPL----RPETPKN--GVSPLFPEP--PKTR 410
T+ +P P + P PK P P TPK +P P P PK
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Query: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETG 470
EP PK E T L P P+ + +P T
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644
Query: 471 VSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKIL 530
L P PE+ EP T P PK EP+ T P PK
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704
Query: 531 VSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTR 590
+ + +++ P P + PK + EP T P PK
Sbjct: 705 APTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTG 650
+ P EP T P P+ EP T + PK + P +T
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTT 814
Query: 651 VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTR 710
P PK + P EP T P PET P P + VS P T+
Sbjct: 815 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTTTK 864
Query: 711 VSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV---SSLRPEPLET 757
+ + P+ L EP + + EP P ++ +PE T
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
Score = 93.2 bits (230), Expect = 1e-18
Identities = 146/637 (22%), Positives = 184/637 (28%), Gaps = 75/637 (11%)
Query: 224 PQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLC 283
P TQ + + P T + P P S E T +E T ++
Sbjct: 236 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 295
Query: 284 PEPP---KTRVSHLHREPPETGVPDLC-----LEPPKSRVSHLRPEPSETGVSHLHPEPP 335
KT + + +T DL L P + P+ T P P
Sbjct: 296 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP 355
Query: 336 KTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETP 395
K S+ EP T + P T P A + P P T+ P P TP
Sbjct: 356 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTP 409
Query: 396 KNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRP-EPPETGVSHLRPEP 454
K P P T+ EP P T+ + P EP T P
Sbjct: 410 KE------PAPTTTK------EPA----------PTTTKSAPTTPKEPAPTTPKKPAPTT 447
Query: 455 PKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRP-EPPDTGVSHLCPEPPKTRVSHLRPE 513
PK + EP T P P K+ + P EP T P PK E
Sbjct: 448 PKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505
Query: 514 PSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE 573
P+ T P PK AP + + + P + P PK E
Sbjct: 506 PAPTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------E 551
Query: 574 PPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPE 633
P T P PK + P +P T P P+ EP T P
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--------EPAPTTTKKPAPT 603
Query: 634 PPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPE 693
PK + E T L P P+ + P +P T L P PE E
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 694 PPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPE 753
P T P PK + EP + EP T P PK + E
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTTPKETAPTTPKGTAPTTLKE 719
Query: 754 PLETRVSHLRP---------EPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPP 804
P T P EP T P PK + EP T P
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 805 KTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSD 841
T + P PT KEL T SD
Sbjct: 780 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816
Score = 92.0 bits (227), Expect = 3e-18
Identities = 147/667 (22%), Positives = 207/667 (31%), Gaps = 81/667 (12%)
Query: 168 QEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKT---PVSSLRPEPPETGVSHLRP 224
+E P +P E +P P+ P EP T P + EP T P
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 225 QPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCP 284
PK + EP T P PK + P T + P + P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSAP 546
Query: 285 EPPKTRVSHLHREP----PETGVPDLCLEP----PKSRVSHLRPEPSETGVSHLHPEPPK 336
PK +EP P+ P +P PK EP+ T P PK
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 337 TLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPK 396
+ E T L P PE + P L P P+ P PE P
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPA 665
Query: 397 NGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPK 456
P PK N EP PK EP T P PK
Sbjct: 666 -------PTTPKAAAPNTPKEPAP--------TTPKEPAPTTPKEPAPTTPKETAPTTPK 710
Query: 457 TRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSE 516
+ EP T P P E + + EP T P PK EP+
Sbjct: 711 GTAPTTLKEPAPTTPKK--PAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 517 TGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPD 576
T P PK + + P ++ +P P E L P K P
Sbjct: 768 TTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKE-----LAPTTTK--------GPTS 812
Query: 577 TGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPK 636
T P PK + P EP T P PET P P + VS P
Sbjct: 813 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET------PPPTTSEVS----TPTT 862
Query: 637 TRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPE--------TRVS 688
T+ + + P+ L EP + + P EP PE T
Sbjct: 863 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Query: 689 HLRPEPPETGVSRLHPEPPKTRVSSLHAE-PPESRVSHLCPEPPETGVSHLRPEPPKPRV 747
LR P T + P T+ ++ E ES+++ + T P ++
Sbjct: 923 DLRTTPETTTAA-----PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KI 973
Query: 748 SSLRPEPLETRVSHLRPEPPETGVSHLHPEL--PKPRVSSLHLEPPKTRRVSSLRLEPPK 805
++L+ L +V+ + T + + E PK R ++ PK ++ + +P
Sbjct: 974 TTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 1033
Query: 806 TGRVSSL 812
T + ++
Sbjct: 1034 TKKPKTM 1040
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/689 (21%), Positives = 215/689 (31%), Gaps = 75/689 (10%)
Query: 152 PLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLR 211
P +P ++ +E P +P +P P+ P EP T
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKP--------APTTPKEPAPTTPKEPAPTTTKEPS 515
Query: 212 PEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLY 271
P P+ P P T+ + + P + P PK + EP T
Sbjct: 516 PTTPK------EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK--- 566
Query: 272 LEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH 331
EP T P PK +EP T PK E + T L
Sbjct: 567 -EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 332 PEPPKTLVSSLHPEPPETGVSHLCPEPPE--TRVSPLRQLP--PEAGVSHLCPEPPKTRV 387
P P+ L + +P T L P PE T +P P P+A + EP T
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 388 PPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGV 447
P TPK EP T PK EP T + +P P E
Sbjct: 686 KEPAPTTPK--------EPAPTTPKETAPTTPKGTAPTTLKEPAPT--TPKKPAPKE--- 732
Query: 448 SHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRV 507
L P K EP T P P+ EP T P PK
Sbjct: 733 --LAPTTTK--------EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782
Query: 508 SHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM 567
EP+ T + PK L + + P ++ P P+ EP T
Sbjct: 783 PTTLKEPAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 839
Query: 568 YSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGV 627
P P+T PP T S P E H P+ +S P P
Sbjct: 840 KKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALEN 891
Query: 628 SHLRPEPPKTRM-YSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE-PPET 685
S P P T+ + +PE T +T + P T + E E+
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Query: 686 RVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKP 745
+++ + T P ++++L +V+ T + + E KP
Sbjct: 952 KITATTTQVTSTTTQDTTP----FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 1007
Query: 746 R---VSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLE 802
+ +S P + + +P T P + KP+ + P R+++S E
Sbjct: 1008 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT------PTPRKMTSTMPE 1061
Query: 803 PPKTGRVS----SLCPEPTKTGASHLKEL 827
T R++ P +T S L E+
Sbjct: 1062 LNPTSRIAEAMLQTTTRPNQTPNSKLVEV 1090
Score = 54.3 bits (129), Expect = 6e-07
Identities = 79/338 (23%), Positives = 99/338 (29%), Gaps = 39/338 (11%)
Query: 90 PKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQV 149
PK KK A + PA K +L P + P E P +
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEE 647
Query: 150 LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEP-PKTPVS 208
L P PE E T P EP +P P+ P EP P TP
Sbjct: 648 LAPTTPE------------EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 209 SLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP----PE 264
P ET + + P T P + L P K S+ +P P+
Sbjct: 696 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 265 TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPE--- 321
EP T P PK +EP T P K L P
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-------TPKKPAPKELAPTTTK 808
Query: 322 -PSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCP 380
P+ T P PK + EP T P PET PP +
Sbjct: 809 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPP--TTSEVS 858
Query: 381 EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEP 418
P T+ P ++P L EP + N EP
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 103 bits (258), Expect = 6e-22
Identities = 126/496 (25%), Positives = 190/496 (38%), Gaps = 63/496 (12%)
Query: 185 EFSPRPPETRVSCLPPEPPKTPVSSLRP-EPPETGVSHLRPQPPKTQVSSLHLEPPETGV 243
+F PE S LP +PPK L+ PE +S + P + ++ L+PP V
Sbjct: 21 KFQASQPEP--SDLPKKPPKPEFGKLKKFSQPE--LSEHPKKAPLPEFGAVSLKPPPPEV 76
Query: 244 SHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGV 303
+ L +PP +V+ L +PP V+ L +PP V+ L +P K +S L ++ P+ G
Sbjct: 77 TDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGA 136
Query: 304 PDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLC--PEPPET 361
+P L+PE E + PEP L P+ +SH P P++
Sbjct: 137 TPFPRKP-------LQPEVGEAPLKASLPEPGAPARKPLQPDE----LSHPARPPSEPKS 185
Query: 362 RVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKI 421
P + PEAG + P+ P +P P+ V P +PP+ ++ L +
Sbjct: 186 GAFPRKLWQPEAGEATPRSPQPELSTFPKKPAQPEFNVYP--KKPPQPQVGGLPKKSVPQ 243
Query: 422 GVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEK 481
+ P + P+ + +PP +S +PP+ + L E
Sbjct: 244 PEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPP---LSDFPKKPPQPELGDLTRTSSEP 300
Query: 482 DVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPES 541
+VS L P L +PP+ + L SE + L P+ L+ + PP
Sbjct: 301 EVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSL----PRKLLQPERRGPPR- 355
Query: 542 SVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPET 601
+PEP H +PE + P P P P SSLP
Sbjct: 356 --KFSQPEPSAVLKRHPQPE-----FFGDLPRKP--------PLPSSASESSLP--AAVA 398
Query: 602 GVSHLCPEPPETRVSHLRPEPPETGVSH-------LRPEPPKTRMYSLRPEPPNTGVSHL 654
G S P P + P G+ H LRP P R RP PP + + H
Sbjct: 399 GFSSRHPLSPGFGAAG-TPRWRSGGLVHSGGARPGLRPSHPPRR----RPLPPASSLGHP 453
Query: 655 CPEPPKTRVSSLPPEP 670
+PP LPP P
Sbjct: 454 PAKPP------LPPGP 463
Score = 89.4 bits (220), Expect = 2e-17
Identities = 95/375 (25%), Positives = 152/375 (40%), Gaps = 41/375 (10%)
Query: 404 PEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEP-PETGVSHLRPEPPKTRVSSL 462
PEP S+L +PPK L H + P PE G L+P PP+ V+ L
Sbjct: 27 PEP-----SDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFGAVSLKPPPPE--VTDL 79
Query: 463 HLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHL 522
+PP V+ L +PP +V+ L +PP V+ L +P K +S L + + G +
Sbjct: 80 PKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPF 139
Query: 523 --RPEPPKILVSSLHQAPPESSVSHLRP-EPPETGVSHLRPEPPKTRMYSLRPEPPDTGV 579
+P P++ + L + PE +P +P E P PK+ + + P+ G
Sbjct: 140 PRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQPEAGE 199
Query: 580 SHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL-RPEPPETGVSHLRPEPPKTR 638
+ P P+ +S+ P +P + + +PP+ +V L + P+ S + P +
Sbjct: 200 A--TPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAA-QTPLWK 256
Query: 639 MYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEP-----------PETGVSHLCPEPPETRV 687
S P+ ++ +PP + PP+P PE V P P E +
Sbjct: 257 PQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKA 316
Query: 688 SHLRPEPPETG-VSRLHPEP-----PKTRVSSLHAEPPE-------SRVSHLCPEPPETG 734
+P PE G + R EP P+ + PP S V P+P G
Sbjct: 317 LSKKPPQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRKFSQPEPSAVLKRHPQPEFFG 376
Query: 735 VSHLRPEPPKPRVSS 749
L +PP P +S
Sbjct: 377 --DLPRKPPLPSSAS 389
Score = 87.8 bits (216), Expect = 5e-17
Identities = 96/362 (26%), Positives = 148/362 (40%), Gaps = 47/362 (12%)
Query: 487 RPEPPDTGVSHLCPEPPKTRVSHLR----PEPSETGVSHLRPEP-PKILVSSLHQAPPES 541
+PEP D L +PPK L+ PE SE H + P P+ SL PPE
Sbjct: 26 QPEPSD-----LPKKPPKPEFGKLKKFSQPELSE----HPKKAPLPEFGAVSLKPPPPEV 76
Query: 542 SVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPET 601
+ +P PPE V+ L +PP + L +PP V+ L +P K +S L + P+
Sbjct: 77 TDLPKKPPPPE--VTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQL 134
Query: 602 GVSHLCPEP--PETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRP-EPPNTGV------- 651
G + +P PE + L+ PE G +P P + RP P +G
Sbjct: 135 GATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQ 194
Query: 652 ---SHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLR----PEPP-----ETGV 699
P P+ +S+ P +P + + +PP+ +V L P+P +T +
Sbjct: 195 PEAGEATPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAAQTPL 254
Query: 700 SRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSL--RPEPLET 757
+ PK S+ + + +S +PP+ + L +P VS L RP P E
Sbjct: 255 WKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEF 314
Query: 758 RVSHLRPEPPETGVSHLHPELPKPRVSSLH---LEPPKTRRVSSLRLEPPKTGRVSSLCP 814
+ +P PE G L +P +SL L+P RR + P+ V P
Sbjct: 315 KALSKKPPQPELG--GLPRTSSEPEFNSLPRKLLQP--ERRGPPRKFSQPEPSAVLKRHP 370
Query: 815 EP 816
+P
Sbjct: 371 QP 372
Score = 87.0 bits (214), Expect = 8e-17
Identities = 119/452 (26%), Positives = 169/452 (37%), Gaps = 75/452 (16%)
Query: 178 PGKYPCGEF---SPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSL 234
P K P EF S +PP V+ LP +PP V+ L +PP V+ L +PP +V+ L
Sbjct: 56 PKKAPLPEFGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDL 115
Query: 235 HLEPPETGVSHLRPEPPKTQVSSLHLEP--PETGVSHLYLEPPGTGVSHLCPEPPKTRVS 292
+P + +S L + P+ + +P PE G + L P G P P +S
Sbjct: 116 PKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQP-DELS 174
Query: 293 HLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVS 352
H R P E PKS + E G P P+ +S+ +P +
Sbjct: 175 HPARPPSE----------PKSGAFPRKLWQPEAG--EATPRSPQPELSTFPKKPAQ---- 218
Query: 353 HLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLF------PEP 406
PE V P + PP+ V L PK VP +PE + +PL+ P+
Sbjct: 219 ------PEFNVYPKK--PPQPQVGGL----PKKSVP--QPEFSEAAQTPLWKPQSSEPKR 264
Query: 407 PKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEP 466
+ S+PP +S +PP+ L E VS L P +L +P
Sbjct: 265 DSSAFPKKASQPP---LSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKP 321
Query: 467 PET---GVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETG-VSHL 522
P+ G+ EP + +P G +P + V P+P G +
Sbjct: 322 PQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRK 381
Query: 523 RPEPPKILVSSLHQAPPESSVSHL---------RPEPPETGVSH-------LRPEPPKTR 566
P P SSL A S H P G+ H LRP P R
Sbjct: 382 PPLPSSASESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGLRPSHPPRR 441
Query: 567 MYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP 598
RP PP + + H +PP LPP P
Sbjct: 442 ----RPLPPASSLGHPPAKPP------LPPGP 463
Score = 86.7 bits (213), Expect = 1e-16
Identities = 121/476 (25%), Positives = 181/476 (38%), Gaps = 56/476 (11%)
Query: 284 PEPPKTRVSHLHREPP--ETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSS 341
PEP S L ++PP E G +P S P P E G L P PP+ V+
Sbjct: 27 PEP-----SDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLP-EFGAVSLKPPPPE--VTD 78
Query: 342 LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSP 401
L +PP V+ L +PP V+ L + PP V+ L +P K + L + P+ G +P
Sbjct: 79 LPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATP 138
Query: 402 LFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRP-EPPETGVSHLRPEPPKTRVS 460
FP P P++G + L P+ +P +P E P PK+
Sbjct: 139 -FPRKPLQ---------PEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAF 188
Query: 461 SLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHL------RPEP 514
L PE G + P P+ ++S +P + +PP+ +V L +PE
Sbjct: 189 PRKLWQPEAGEA--TPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEF 246
Query: 515 SETGVSHL---RPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLR 571
SE + L + PK S+ + + +S +PP+ + L TR S
Sbjct: 247 SEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDL------TRTSS-- 298
Query: 572 PEPPDTGVSHLCPEPPKTR-VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHL 630
P+ V P P + + +S PP+P G+ EP + +P G
Sbjct: 299 --EPEVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRK 356
Query: 631 RPEPPKTRMYSLRPEPPNTG-VSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSH 689
+P + + P+P G + P P SSLP G S P P +
Sbjct: 357 FSQPEPSAVLKRHPQPEFFGDLPRKPPLPSSASESSLP--AAVAGFSSRHPLSPGFGAAG 414
Query: 690 LRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKP 745
P G+ P R S PP R P PP + + H +PP P
Sbjct: 415 -TPRWRSGGLVHSGGARPGLRPS----HPPRRR-----PLPPASSLGHPPAKPPLP 460
Score = 69.3 bits (168), Expect = 2e-11
Identities = 92/396 (23%), Positives = 147/396 (37%), Gaps = 24/396 (6%)
Query: 150 LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSS 209
LKP PE + D + TD P +P + +PP V+ LP +P K +S
Sbjct: 69 LKPPPPE--VTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSD 126
Query: 210 LRPEPPETGVSHL--RPQPPKTQVSSLHLEPPETGVSHLRP-EPPKTQVSSLHLEPPETG 266
L + P+ G + +P P+ + L PE G +P +P + + P++G
Sbjct: 127 LSKKFPQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSG 186
Query: 267 VSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHL------RP 320
L P G P P+ +S ++P + +PP+ +V L +P
Sbjct: 187 AFPRKLWQPEAG--EATPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQP 244
Query: 321 EPSETGVSHL---HPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQL--PPEAGV 375
E SE + L PK S+ + + +S +PP+ + L + PE V
Sbjct: 245 EFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSV 304
Query: 376 SHLCPEPPKTRVPPLRPETPKNGVSP-LFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTR 434
P P + + +P P+ G P EP + +P + G +P +
Sbjct: 305 LPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRKFSQPEPSA 364
Query: 435 GSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTG 494
P+P G +P P + S L G S P P + P G
Sbjct: 365 VLKRHPQPEFFGDLPRKPPLPSS-ASESSLPAAVAGFSSRHPLSPGFGAAG-TPRWRSGG 422
Query: 495 VSHLCPEPPKTRVSH---LRPEPSETGVSHLRPEPP 527
+ H P R SH RP P + + H +PP
Sbjct: 423 LVHSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPP 458
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 96.7 bits (239), Expect = 1e-19
Identities = 134/472 (28%), Positives = 170/472 (36%), Gaps = 111/472 (23%)
Query: 248 PEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLC 307
P PP T S PP T + L PP T P PP T + PP T P
Sbjct: 1399 PSPPTTTPS-----PPPTSTTTL---PPTT-----TPSPPTTTTT----TPPPTTTPS-- 1439
Query: 308 LEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLR 367
PP + + P P+ T P PP +S+ PP T P PP T SP
Sbjct: 1440 --PPITTTT--TPPPTTT------PSPP---ISTTTTPPPTT-----TPSPPTTTPSPPT 1481
Query: 368 QLPPEAGVSHLCPEPPKTRVPPLR-PETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHL 426
P + P P T PP P TP + L PP T S PP +
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL---PPTTTPS-----PPTTTTT-- 1531
Query: 427 CLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHL 486
PP T P PP T P P T ++L PP T P PP +
Sbjct: 1532 --TPPPTT----TPSPPTT-----TPITPPTSTTTL---PPTT-----TPSPPPTTTTTP 1572
Query: 487 RPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHL 546
P + + P PP ++ P P+ T P PP ++ PP ++
Sbjct: 1573 PPTTTPSPPTTTTPSPPT--ITTTTPPPTTT------PSPPTTTTTT----PPPTTT--- 1617
Query: 547 RPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHL 606
P PP T P P T +L PP T P PP T ++ PP + +
Sbjct: 1618 -PSPPTT-----TPITPPTSTTTL---PPTT-----TPSPPPTTTTTPPPTTTPSPPTTT 1663
Query: 607 CPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSL 666
P PP T + P + P PP T M + P P T S + T S+
Sbjct: 1664 TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT--PSPTTTPSSPITTTT--TPSSTT 1719
Query: 667 PPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEP 718
P PP T ++ P P T P PP T ++ L PP T S L P
Sbjct: 1720 TPSPPPTTMT--TPSPTTT------PSPPTTTMTTL---PPTTTSSPLTTTP 1760
Score = 92.0 bits (227), Expect = 3e-18
Identities = 144/520 (27%), Positives = 177/520 (34%), Gaps = 127/520 (24%)
Query: 165 CEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRP 224
C +K P+ P +P PP T + LPP +P ++ PP T P
Sbjct: 1389 CWPMDKCITTPSPPTT------TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPT----TTP 1438
Query: 225 QPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCP 284
PP T ++ PP T P PP +S+ PP T S PP T P
Sbjct: 1439 SPPITTTTT----PPPT----TTPSPP---ISTTTTPPPTTTPS-----PPTT-----TP 1477
Query: 285 EPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHP 344
PP T S PP T PP + S P+ T ++ P TL + P
Sbjct: 1478 SPPTTTPS-----PPTT---TTTTPPPTTTPS----PPTTTPIT--PPASTTTLPPTTTP 1523
Query: 345 EPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFP 404
PP T + PP T SP P S P T PP P T P
Sbjct: 1524 SPPTTTTT---TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--PTTTTTPPPTTTP 1578
Query: 405 EPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHL 464
PP T + PP I + PP T P PP T + PP T S
Sbjct: 1579 SPPTTTTPS----PPTITTT----TPPPT----TTPSPPTTTTT----TPPPTTTPS--- 1619
Query: 465 EPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRP 524
PP T P P + L PP T P PP T + P P+ T P
Sbjct: 1620 -PPTT-----TPITPPTSTTTL---PPTT-----TPSPPPTTTT--TPPPTTT------P 1657
Query: 525 EPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCP 584
PP + P PP T + P + + P PP T ++
Sbjct: 1658 SPP----------------TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT---- 1697
Query: 585 EPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRP 644
P T S P T S P PP T ++ P P T P PP T M +L
Sbjct: 1698 TPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT--TPSPTTT------PSPPTTTMTTL-- 1747
Query: 645 EPPNTGVSHL--CPEPPKTRVSSLPP---EPPETGVSHLC 679
PP T S L P PP + P P T LC
Sbjct: 1748 -PPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLC 1786
Score = 88.6 bits (218), Expect = 3e-17
Identities = 123/452 (27%), Positives = 149/452 (32%), Gaps = 86/452 (19%)
Query: 344 PEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLF 403
P PP T S P P T P P + P P T PP+ T +
Sbjct: 1399 PSPPTTTPS---PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT-- 1453
Query: 404 PEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLH 463
P PP IS + PP S PP T P PP T P PP T ++
Sbjct: 1454 PSPP---ISTTTTPPPTTTPS-----PPTTT-----PSPPTT-----TPSPPTTTTTT-- 1493
Query: 464 LEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLR 523
PP T P + PP T P PP T + P P+ T
Sbjct: 1494 --PPPTTTPSPPTTTPITPPASTTTLPPTT-----TPSPPTTTTT--TPPPTTT------ 1538
Query: 524 PEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLC 583
P PP ++ PP S+ + PP T P PP T + P P T
Sbjct: 1539 PSPP----TTTPITPPTSTTTL----PPTT-----TPSPPPTT--TTTPPPTTT------ 1577
Query: 584 PEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLR 643
P PP T S P T P PP T + PP T P PP T
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTT----TPPPTTT----PSPPTTT----- 1624
Query: 644 PEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLH 703
P P T + L P T S PP T P PP T P PP T +
Sbjct: 1625 PITPPTSTTTL----PPTTTPSPPPTTTTTPPPTTTPSPPTTTT----PSPPITTTTT-- 1674
Query: 704 PEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPE--PPKPRVSSLRPEPLETRVSH 761
P P T S + P + P P T S + P S P + T
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 762 LRPEPPETGVSHLHPELPKPRVSSLHLEPPKT 793
P PP T ++ L P +++ L P T
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTPLPPSIT 1766
Score = 88.2 bits (217), Expect = 4e-17
Identities = 113/409 (27%), Positives = 150/409 (36%), Gaps = 100/409 (24%)
Query: 440 PEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLC 499
P PP T P PP T ++L PP T P PP + PP T
Sbjct: 1399 PSPPTT-----TPSPPPTSTTTL---PPTT-----TPSPPTTTTT----TPPPTTT---- 1437
Query: 500 PEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLR 559
P PP T + P P+ T P PP +S+ PP ++ P PP T
Sbjct: 1438 PSPPITTTT--TPPPTTT------PSPP---ISTTTTPPPTTT-----PSPPTT-----T 1476
Query: 560 PEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLR 619
P PP T P PP T + PP T S P P T + PP T
Sbjct: 1477 PSPPTTT-----PSPPTTTTT----TPPPTTTPSPPTTTPITPPASTTTLPPTTT----- 1522
Query: 620 PEPPETGVSH----LRPEPPKTRMYSLRPEPPNTGVSHL----CPEPPKTRVSSLPPEPP 671
P PP T + P PP T P P T + L P PP T ++ PP
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTT-----PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577
Query: 672 ETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEP- 730
+ + P PP ++ P P T P PP T ++ PP + S P
Sbjct: 1578 PSPPTTTTPSPPT--ITTTTPPPTTT------PSPPTTTTTT---PPPTTTPSPPTTTPI 1626
Query: 731 -PETGVSHLRPE--PPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLH 787
P T + L P P P ++ P P T P PP T P P +++
Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTT------PSPPTTTT-------PSPPITTTT 1673
Query: 788 LEPPKTRRVSSLRLEP-PKTGRVSSLCPEPTKTGASHLKELFQEGTSST 835
PP T S + P P T +++ P PT T +S + +++T
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTT--PSPTTTPSSPITTTTTPSSTTT 1720
Score = 33.9 bits (76), Expect = 0.82
Identities = 54/203 (26%), Positives = 70/203 (34%), Gaps = 19/203 (9%)
Query: 171 TTDEPTEPGKYPCGEFSPRP-PETRVSCLPPEPPKTPVSSLRPEP-PETGVSHLRPQPPK 228
TT P P G +P P T + + P P TP + P P T + + P P
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 4144
Query: 229 TQVSSLHLEPPETGVSHL-RPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPP 287
T + P T + P P TQ + P T + + P TG P
Sbjct: 4145 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTGPPTHT 4201
Query: 288 KTR-VSHL--HREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHP--EPPKTLVSSL 342
T ++ L PPE+ P SR + S T +S L P E T S
Sbjct: 4202 STAPIAELTTSNPPPESSTPQT------SRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255
Query: 343 HPEPPETGVSHLCPEPPETRVSP 365
P T H PP T SP
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSP 4278
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 93.2 bits (230), Expect = 1e-18
Identities = 153/660 (23%), Positives = 240/660 (36%), Gaps = 119/660 (18%)
Query: 149 VLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVS 208
++ PL P+ K+ T +P+ P P P PP PP PP P+
Sbjct: 605 LVPPLSPQPKIVTP-------YTASQPSPPLPPPPPPPPPPPP-------PPPPPPPPLP 650
Query: 209 SLRPEPPETGVSHLRPQPPK-TQVSSLHLEPPETGVSHLRPEPPKTQVSSLH---LEPPE 264
S P G + P K + ++ L +G P PP Q S+ L PP
Sbjct: 651 S--QSAPSAGSA--APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN 706
Query: 265 TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSE 324
V PP P P + ++ L P +P PP ++ ++
Sbjct: 707 GVVPPPPPPPP--------PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ---HI 755
Query: 325 TGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPK 384
T V+ P PP + + L P+ P P+P T +P V+ P P
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAP--------PKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807
Query: 385 TRVPPLR--PETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEP 442
VPP + P P + + P P PP + PP + PK + +P P
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPP------VPVPPPTL---------PKQQSFCAKPPP 852
Query: 443 PETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEP 502
S L P P + + PP P PP + L+P P +++ P+
Sbjct: 853 -----SPLSPVPSVVKQIASQFPPP--------PTPPAMESQPLKPVP-----ANVAPQS 894
Query: 503 PKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEP 562
P + + +PS V PP PPESS+ + P PP + V P P
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPP----------PPESSL--VFPPPPPSPVPAPPPPP 942
Query: 563 PKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPE--------TGVSHLCPEPP--E 612
P T P P +G + PP P+ +G H P+ P +
Sbjct: 943 PPT----ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVD 998
Query: 613 TRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVS--HLCPEPPKTRVSSLPPEP 670
+ VS P P E+G PP + P+P +S +L + VS+ P
Sbjct: 999 SLVSKFTP-PAESGSPSKETLPPP----AAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 671 PETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEP 730
G + P S P PPET + P PP + ++ + +V+ + P+P
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETEL----PLPP-IEIPAVFSGNTSPKVAVVNPQP 1108
Query: 731 PETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEP 790
+ ++ PP R R + + + +P ++ + P++P SSL ++P
Sbjct: 1109 QQWSKMSVKKAPPPTRPK--RNDSTRLTQAEISEQPT---MATVVPQVPTSPKSSLSVQP 1163
Score = 81.3 bits (199), Expect = 4e-15
Identities = 150/623 (24%), Positives = 230/623 (36%), Gaps = 89/623 (14%)
Query: 227 PKTQVSSLHLEPPETGVSHLRPEP---PKTQVSSLHLEPPETGV-----SHLYLE----P 274
P++Q S H ++GVS +P ++ VSS+ E + G S +E P
Sbjct: 544 PESQ--SNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRP 601
Query: 275 PGTGVSHLCPEPP-KTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPE 333
+ V L P+P T + PP P PP P PS++ S
Sbjct: 602 YTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAA 661
Query: 334 P---PKTLVSSLHPEPPETGVSHLCPEPPETR---VSPLRQLPPEAGVSHLCPEPPKTRV 387
P + ++ L +G P PP + V P +PP V P PP
Sbjct: 662 PMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVV----PPPP---- 713
Query: 388 PPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIG---VSHLCLEPPKTRGSHLRPEPPE 444
PP P TP + ++ L P P + + PP + V H+ P T P PP
Sbjct: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT------PPPPP 767
Query: 445 TGVSHLRPE-PPKTRV------SSLHLEPPETGVSHLCPEPPEKDV--------SHLRPE 489
+ L P+ PPK V S+ + P T + P PP S++ P
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 490 PPDTGVSHLCPEPPKTRVSHLRPEPSETG-----VSHLRPE-PPKILVSSLHQAPPESSV 543
PP V P PK + +P PS V + + PP ++ P +
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Query: 544 SHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGV 603
+++ P+ P + + +P + S PP S + P PP + V + PP PP T
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT-- 945
Query: 604 SHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRV 663
P+ S + + +P P R S++ ++G H PEP + V
Sbjct: 946 ---ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK---SSSGAEH--PEPKRPSV 997
Query: 664 SSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVS--SLHAEPPES 721
SL VS P P E+ PP P+P K +S +L +
Sbjct: 998 DSL--------VSKFTP-PAESGSPSKETLPPPAA----PPKPGKLNLSGVNLPGVLQQG 1044
Query: 722 RVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKP 781
VS P G + P P S P P ET + P PP + + P
Sbjct: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL----PLPP-IEIPAVFSGNTSP 1099
Query: 782 RVSSLHLEPPKTRRVSSLRLEPP 804
+V+ ++ +P + ++S + PP
Sbjct: 1100 KVAVVNPQPQQWSKMSVKKAPPP 1122
Score = 47.8 bits (112), Expect = 5e-05
Identities = 98/400 (24%), Positives = 140/400 (35%), Gaps = 92/400 (23%)
Query: 142 PPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPE 201
PP + Q LKP+ + + + + K P +F P PPE+ S + P
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP---VPSPDFPPPPPES--SLVFPP 929
Query: 202 PPKTPVSSLRPEPPETGVSHLRPQPPKT---------QVSSLHLEPPET----------- 241
PP +PV + P PP T P P K+ S +PP T
Sbjct: 930 PPPSPVPAPPPPPPPTA----SPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985
Query: 242 GVSHLRPEPPKTQVSSL---HLEPPETG-VSHLYLEPPGTGVSHLCPEPPKTRVSHLH-- 295
G H PEP + V SL P E+G S L PP P+P K +S ++
Sbjct: 986 GAEH--PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP-----PKPGKLNLSGVNLP 1038
Query: 296 ----------REPPETG-VPDLCLE-PPKSRVSHLRPEPSETGVSHLHPEPPKTL----- 338
+ P +G D +E P S P P ET + P PP +
Sbjct: 1039 GVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL----PLPPIEIPAVFS 1094
Query: 339 ------VSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRP 392
V+ ++P+P + + PP TR P R + + +P V P P
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTR--PKRNDSTRLTQAEISEQPTMATVVPQVP 1152
Query: 393 ETPKNGVS--PLF--------PEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEP 442
+PK+ +S P F TR +L S + EP T P P
Sbjct: 1153 TSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSR-------AEPTATMDDMALPPP 1205
Query: 443 PETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKD 482
P L + K H+ T P PP++D
Sbjct: 1206 P----PELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRD 1241
Score = 46.2 bits (108), Expect = 2e-04
Identities = 94/413 (22%), Positives = 144/413 (34%), Gaps = 81/413 (19%)
Query: 190 PPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPE 249
PP + +P K +++ P+ P + + QP V S PP S + P
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 250 PPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLE 309
PP + V + PP T P P K+ ++ +T P
Sbjct: 930 PPPSPVPAPPPPPPPTA----------------SPTPDKS--GSPGKKTSKTSSPGGKKP 971
Query: 310 PP-KSRVSHLRPEPSETGVSHLHPEPPK--TLVSSLHPEPPETGVSHLCPEPPETRVSPL 366
PP R S ++ S +G H P+ P +LVS P P E+G P P
Sbjct: 972 PPTPQRNSSIK---SSSGAEHPEPKRPSVDSLVSKFTP-PAESG-------SPSKETLPP 1020
Query: 367 RQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPL-----------FPEPPKTRISNLR 415
PP+ G +L +P + + + +P+ FP PP S+
Sbjct: 1021 PAAPPKPGKLNL----SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSD--SDFP 1074
Query: 416 SEPPKIGVSHLCLEPPKTRGSH-------LRPEPPETGVSHLRPEPPKTRV---SSLHLE 465
PP+ + +E P + + P+P + ++ PP TR S L
Sbjct: 1075 PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLT 1134
Query: 466 PPETG----VSHLCPEPPEKDVSHLRPEPPD-TGVSHLCPEPPKTRVSHL-----RPEPS 515
E ++ + P+ P S L +P ++ TR L R EP+
Sbjct: 1135 QAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPT 1194
Query: 516 ETGVSHLRPEPPKILVSSLHQA----PPESSVSHLRPEPPETGVSHLRPEPPK 564
T P PP L+S +A S + LR PP P PPK
Sbjct: 1195 ATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPP--------PAPPK 1239
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 92.4 bits (228), Expect = 2e-18
Identities = 167/666 (25%), Positives = 221/666 (33%), Gaps = 100/666 (15%)
Query: 167 GQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHL---R 223
G + T PT P R T V P P S RP PP G
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP------SARPRPPTEGPRKSVSSA 212
Query: 224 PQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPP-ETGVSHLYLEPPGTGVSHL 282
+ T+ S P G RP S+ L P +G S GT +
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS-----ARGTPRAPA 267
Query: 283 CPEPPKTRVSHLHREPPETGVPDLCLEP---PKSRVSHLRPEPSETGVSHLHPEPPKTLV 339
P PK + R PP+ P P P S P PS T P PP
Sbjct: 268 HPSQPKPKGLQALR-PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA---RPVPPPDNA 323
Query: 340 SSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGV 399
++ P + L P PP PL P A PP + P P TP +
Sbjct: 324 ATPLP-------ATLPPSPPLATPLPLAPPSPSA--------PPSLQTLPSPPATPPSQA 368
Query: 400 SPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPP---- 455
P PP +L++ PP I V H P L+ P +S L+
Sbjct: 369 PPSMTTPPMQAPPSLQTIPP-IQVPHSLTSP------SLQAPPSPLALSSLQATTSLGSP 421
Query: 456 --KTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPE 513
+ S L + P +T S P P + P+ P P P + S
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRP----ASTPPDSPPLQAPLSLPASPPLQTS---LS 474
Query: 514 PSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPE----------PP 563
P+ + +S P +SSL P++ +S L P ET S P PP
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534
Query: 564 KTRMYSLRPEPPDTGVSHL---------CPEPPKTRV--SSLPPEPPETGVSHLCPEPPE 612
+ SL P P T + L CP P + S L PPET S P P
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP-- 592
Query: 613 TRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE-PPNTGVSHLCPEPPKTRVSSLPPEPP 671
+ PP G+ P PP + + + P+ PP + PP S P PP
Sbjct: 593 -QAPPALASPPLQGL----PSPPLSPLATPPPQAPPXLAL------PPLQAPPSPPASPP 641
Query: 672 ETGVSHLCPEPPETRVSHLRP---EPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCP 728
+ ++ P+ P HL PP + + PP + S A PP L
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 729 EPPETGVSHLRPEPPKPRVS--SLRPEPLETRVSHLRPEPPETGVSHLHPE-LPKPRVSS 785
P + S P P + P PL + P PP + + P P PRV
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMSPSATPPPRVPP 759
Query: 786 LHLEPP 791
L PP
Sbjct: 760 LLAAPP 765
Score = 75.5 bits (184), Expect = 2e-13
Identities = 145/579 (25%), Positives = 185/579 (31%), Gaps = 112/579 (19%)
Query: 175 PTEPGKYPCGEFSPRPPETRVSCLPPEPPK--------TPVSSLRPEPPETGVSHLRPQP 226
P+ P P PP LP PP +P+SS P +S L
Sbjct: 444 PSRPASTP----PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 227 PKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEP 286
P+ +SSL + P ET S L P +T +SL PP + L P P
Sbjct: 500 PQAPLSSLIMPPLETQ-SSLAPPSLQTPPASL-------------TTPPLENLPSLAPPP 545
Query: 287 PKTRVSHL---HREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEP--PKTLVSS 341
+T + L H E P P PP S L P ET S P P P L S
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPP----SPLTTPPPETPSSIATPPPQAPPALAS- 600
Query: 342 LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLR---------P 392
PP G+ P PP +SPL PP+A PP +PPL+ P
Sbjct: 601 ----PPLQGL----PSPP---LSPLATPPPQA--------PPXLALPPLQAPPSPPASPP 641
Query: 393 ETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLR- 451
+P SP P + PP PP + PP L
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 452 ------PEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKT 505
P PP + S PP L P + + P PP + PP
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ-----VPPSPPASPPMSPSATPPPR 756
Query: 506 RVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLR--PEPPET--GVSHLRPE 561
L P + S P L QAPP + L+ P PP + G + P
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 562 P--PKTRMYSLRPEPPDTGVSHLC---PEPPKTRVSSLPPEPPETGVSHLCPEPPETRVS 616
P + + + P+ P + L P PP + P PP G P+T VS
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--------PDTSVS 868
Query: 617 HLR---------PEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLP 667
R P PP S P S P + P+ ++ P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY--DSGPEGGAAASP 926
Query: 668 PEPPETGVSHLC-----PEPP---ETRVSHLRPEPPETG 698
P E H P PP P PP TG
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965
Score = 63.9 bits (154), Expect = 7e-10
Identities = 141/565 (24%), Positives = 195/565 (34%), Gaps = 99/565 (17%)
Query: 86 PQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDL 145
P + P L L + LSPA V + + L T HPL +L P
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPA-------VSPLSSPL-TIHPLQALSSLASHSPQAP 503
Query: 146 LLQ-VLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVS-------- 196
L ++ PL+ + L T P E +P P +T +
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN----LPSLAPPPLQTASAPLTTPHLE 559
Query: 197 ---CLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKT 253
C P P + P S L PPET S P P Q PP G+ P PP +
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP---QAPPALASPPLQGL----PSPPLS 612
Query: 254 QVSSLHLE-PPETGVSHLYL------EPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDL 306
+++ + PP + L PP + ++ P+ P HL + P + P
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSP 671
Query: 307 CLEPPKSRVSHLRPEPSETGVSHLHPE---PPKTLVSSLHPEPPETGVSHLCPEPPETRV 363
++ P S + PS T S P PP + S PP + + P+ P
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 364 SPLRQLPPEAGVSH-LCPE-------PPKTRVPPLR--PETPKN-GVSPLFPEPPKTRIS 412
+P Q+PP S + P PP PPL+ P P + +SPL PP+
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA--- 788
Query: 413 NLRSEPPKIGVSHL-CLEPPKTRGSHLRPEPPETG--VSHLRPEPPKTRVSSLHLEPPET 469
PP + L L P P P +S L PP+ + L P
Sbjct: 789 -----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ---APPVLAAPLL 840
Query: 470 GVSHLCPEPPEKDVSHLRPEP-PDTGVS------HLCPEPPKTRVSHLRPEPSETGVSHL 522
V P P P P PDT VS L P PP P PS + S L
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--------PPPSRSPSSTL 892
Query: 523 RPEPPKILVSSLHQAPPESSVSHLR--PEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVS 580
P + + H + S+ LR PE G + PP + + P G
Sbjct: 893 --SGPDL---AGHSSSATSTPEELRGYDSGPEGGAA--ASPPPDAELAACHPAAWSRG-- 943
Query: 581 HLCPEPP---KTRVSSLPPEPPETG 602
P PP + + P PP TG
Sbjct: 944 ---PAPPLAFRGAPGAPLPWPPATG 965
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 86.7 bits (213), Expect = 1e-16
Identities = 186/761 (24%), Positives = 261/761 (34%), Gaps = 95/761 (12%)
Query: 88 ADPKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLL 147
+D K+ K + K A + S + ++ EE+ + +++P
Sbjct: 43 SDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSP 102
Query: 148 QVLKPLDPERKLEDAGSCEGQEKTTDE-PTEPGKYPCGEFS------------PRPPETR 194
L LD R L D GS + ++ D T P Y G P P
Sbjct: 103 SDLDSLDG-RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP 161
Query: 195 VSCLPPEP------PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRP 248
PP P P+ P +S P P T + P P T S + PP H +
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT--SRMFQAPPGAPPPHPQL 219
Query: 249 EPPKT-QVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLH--------REPP 299
P T V S P+ G + + P G H PP T +S +PP
Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQH---PPPTTPISVSSSGASGAPPTKPP 276
Query: 300 ET--GVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPE 357
T G +L PP + H+ P +L P P +++ PP G L
Sbjct: 277 TTPVGGGNLPSAPPPANFPHVTP--------NLPPPPALRPLNNASASPPGLGAQPLPGH 328
Query: 358 PPETRV--SPLRQLP--PEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISN 413
P + LP PE G + L P P +PP P + FP + S
Sbjct: 329 LPSPHAMGQGMGGLPPGPEKGPT-LAPSPHS--LPPASSSAPAPPMR--FPYSSSSSSSA 383
Query: 414 LRSEPPKIGVSHLCLEP-PKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVS 472
S S P + S+ PP T +S + +PPK SL P V
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-VSNQPPKYTQPSL----PSQAVW 438
Query: 473 HLCPEPP-------EKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPE 525
P PP +H P PP TG P T H + + + + +
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 526 PPKILVSSLHQAPPESSVSHLRPEPPETGVS-HLRPEPPKTRMYSLRPEPPDTGVSHLCP 584
+ + PP + P P E G S H P + SLRP PP G +HL
Sbjct: 499 QQQQHHGNSGPPPPGAF-----PHPLEGGSSHHAHPYAMSPSLGSLRPYPP--GPAHL-- 549
Query: 585 EPPKTRVS---SLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYS 641
PP ++VS + P PP + S+ + P P + P PP + +
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV-T 608
Query: 642 LRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSR 701
+T ++ + P + +S PP PP G P P + + P + S
Sbjct: 609 TSSATLSTVIATVASSPAGYKTAS-PPGPPPYG--KRAPSPGAYKTATPPGYKPGSPPSF 665
Query: 702 LHPEPPKTRVSSLHAEP----PESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLET 757
PP R +S A P P S P PP G S L PP P + P T
Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPP-AGPSGLPSLPPPPAAPASGPPLSAT 724
Query: 758 RVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS 798
++ E ET PE P P S PPK V S
Sbjct: 725 QIKQEPAEEYET------PESPVPPARS-PSPPPKVVDVPS 758
Score = 49.3 bits (116), Expect = 2e-05
Identities = 62/230 (26%), Positives = 82/230 (35%), Gaps = 38/230 (16%)
Query: 596 PEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRP-EPPKTRMYSLRPEPPNTGVSHL 654
P+PP++ P PE + P P T + P EPP +RM+ PP H
Sbjct: 169 PQPPDS-----TPRQPE---ASFEPHPSVTPTGYHAPMEPPTSRMFQA---PPGAPPPHP 217
Query: 655 CPEPPKTR-VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPP----ETGVSRLHP-EPPK 708
P T V S PP P+ G + P H P P +G S P +PP
Sbjct: 218 QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
Query: 709 TRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPE 768
T V +L PP H+ P P P +LRP +++ PP
Sbjct: 278 TPVGG----------GNLPSAPPPANFPHVTPNLPPP--PALRP------LNNASASPPG 319
Query: 769 TGVSHLHPELPKPRVSSLHLE--PPKTRRVSSLRLEPPKTGRVSSLCPEP 816
G L LP P + PP + +L P SS P P
Sbjct: 320 LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAP 369
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 86.7 bits (213), Expect = 1e-16
Identities = 186/761 (24%), Positives = 261/761 (34%), Gaps = 95/761 (12%)
Query: 88 ADPKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLL 147
+D K+ K + K A + S + ++ EE+ + +++P
Sbjct: 43 SDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSP 102
Query: 148 QVLKPLDPERKLEDAGSCEGQEKTTDE-PTEPGKYPCGEFS------------PRPPETR 194
L LD R L D GS + ++ D T P Y G P P
Sbjct: 103 SDLDSLDG-RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP 161
Query: 195 VSCLPPEP------PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRP 248
PP P P+ P +S P P T + P P T S + PP H +
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT--SRMFQAPPGAPPPHPQL 219
Query: 249 EPPKT-QVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLH--------REPP 299
P T V S P+ G + + P G H PP T +S +PP
Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQH---PPPTTPISVSSSGASGAPPTKPP 276
Query: 300 ET--GVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPE 357
T G +L PP + H+ P +L P P +++ PP G L
Sbjct: 277 TTPVGGGNLPSAPPPANFPHVTP--------NLPPPPALRPLNNASASPPGLGAQPLPGH 328
Query: 358 PPETRV--SPLRQLP--PEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISN 413
P + LP PE G + L P P +PP P + FP + S
Sbjct: 329 LPSPHAMGQGMGGLPPGPEKGPT-LAPSPHS--LPPASSSAPAPPMR--FPYSSSSSSSA 383
Query: 414 LRSEPPKIGVSHLCLEP-PKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVS 472
S S P + S+ PP T +S + +PPK SL P V
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-VSNQPPKYTQPSL----PSQAVW 438
Query: 473 HLCPEPP-------EKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPE 525
P PP +H P PP TG P T H + + + + +
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 526 PPKILVSSLHQAPPESSVSHLRPEPPETGVS-HLRPEPPKTRMYSLRPEPPDTGVSHLCP 584
+ + PP + P P E G S H P + SLRP PP G +HL
Sbjct: 499 QQQQHHGNSGPPPPGAF-----PHPLEGGSSHHAHPYAMSPSLGSLRPYPP--GPAHL-- 549
Query: 585 EPPKTRVS---SLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYS 641
PP ++VS + P PP + S+ + P P + P PP + +
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV-T 608
Query: 642 LRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSR 701
+T ++ + P + +S PP PP G P P + + P + S
Sbjct: 609 TSSATLSTVIATVASSPAGYKTAS-PPGPPPYG--KRAPSPGAYKTATPPGYKPGSPPSF 665
Query: 702 LHPEPPKTRVSSLHAEP----PESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLET 757
PP R +S A P P S P PP G S L PP P + P T
Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPP-AGPSGLPSLPPPPAAPASGPPLSAT 724
Query: 758 RVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS 798
++ E ET PE P P S PPK V S
Sbjct: 725 QIKQEPAEEYET------PESPVPPARS-PSPPPKVVDVPS 758
Score = 49.3 bits (116), Expect = 2e-05
Identities = 62/230 (26%), Positives = 82/230 (35%), Gaps = 38/230 (16%)
Query: 596 PEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRP-EPPKTRMYSLRPEPPNTGVSHL 654
P+PP++ P PE + P P T + P EPP +RM+ PP H
Sbjct: 169 PQPPDS-----TPRQPE---ASFEPHPSVTPTGYHAPMEPPTSRMFQA---PPGAPPPHP 217
Query: 655 CPEPPKTR-VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPP----ETGVSRLHP-EPPK 708
P T V S PP P+ G + P H P P +G S P +PP
Sbjct: 218 QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
Query: 709 TRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPE 768
T V +L PP H+ P P P +LRP +++ PP
Sbjct: 278 TPVGG----------GNLPSAPPPANFPHVTPNLPPP--PALRP------LNNASASPPG 319
Query: 769 TGVSHLHPELPKPRVSSLHLE--PPKTRRVSSLRLEPPKTGRVSSLCPEP 816
G L LP P + PP + +L P SS P P
Sbjct: 320 LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAP 369
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 83.6 bits (205), Expect = 9e-16
Identities = 149/681 (21%), Positives = 238/681 (34%), Gaps = 121/681 (17%)
Query: 138 GEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSP---RPPETR 194
GE + P L P+ + G EK+ P +P P G P +P +
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 195 VSCLPP---EPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLR---P 248
PP +PP P+ +P +TG + P + + +PP G + + P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA---QPPGVGKTPAQQPGP 407
Query: 249 EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCL 308
P TQ + G + PG P P KT V
Sbjct: 408 AKPPTQ---------QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ---------------- 442
Query: 309 EPPKSRVSHLRPEPSETGVSHLHP-EPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLR 367
+P ++ + P +T P +PP L P P + G + P+ P + P +
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 368 Q------LPPEAGVSHLCPEPP-KTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPK 420
Q P + G + P+ P T+ P +P + K P P + S ++P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS---TKPVS 559
Query: 421 IGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
S L+PP S +PP G+ + P + L L PE + C E
Sbjct: 560 QTGSGKPLQPPTVSPS--AKQPPSQGLP--KTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 481 K--DVSHLRPEPPDTGVSH-LC----------------PEPPKTRVSHLRPEPSETGVSH 521
+ P P T V LC P P+ ++ P + + VS
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK-TAPVTTTSAVSK 674
Query: 522 LRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSH 581
P+P + S A P+ +S PEP + PP + +L P S
Sbjct: 675 SSPQPQQ--TSPKKDAAPKQDLSK-APEP--------KKPPPLVKQPTLHGSP-----SA 718
Query: 582 LCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRP--EPPKTRM 639
+PP+ S P P E V E + V+ +P+ P+ ++P + +
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVP---SEQDKAPVADDKPKQPKM----VKPTTDLVSSSS 771
Query: 640 YSLRPEPPNTGVSHLCPE---PPKTRVSSLPPEP-PETGV------SHLCPEPPETR--V 687
+ +P+ P++ V E PP S+ P + P TG S P P +
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 688 SHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV 747
SH P G ++ P K E P+ + + P+P + P PP PR
Sbjct: 832 SHPGPSSESKGQKQVDPVQKK--------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 748 SSLRPEPLETRVSHLRPEPPE 768
++ + P + P+P E
Sbjct: 884 TAGQTVPTPQQ----SPKPQE 900
Score = 50.4 bits (119), Expect = 8e-06
Identities = 169/768 (22%), Positives = 260/768 (33%), Gaps = 127/768 (16%)
Query: 137 LGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVS 196
LG D+ P P P+ KL+ A + P P + +P+ ++
Sbjct: 646 LGGDLAP-------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA- 697
Query: 197 CLPPEPPKTPVSSLRP-----------EPPETGVSHLRPQPPKTQVSSLHLEPPETGVSH 245
PEP K P +P +PPE S +P PPK S+ E + V+
Sbjct: 698 ---PEPKKPPPLVKQPTLHGSPSAKAKQPPEAD-SLSKPAPPKEP--SVPSEQDKAPVAD 751
Query: 246 LRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPE----PPKTRVSHLHREPPET 301
+P+ PK + L + + + P + V E P KT + + P T
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 302 G-----VPDLCLEPPKSR---VSHLRPEPSETGVSHLHP----EPPKTLVSSLHPEPPET 349
G + P S +SH P G + P E PK + + P+P
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 350 GVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPK------------TRVPPLRPETPKN 397
+ P PP R + + +P P+P + T P +P TP+
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVP----TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Query: 398 GVSPL---FPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEP 454
V+ F ++ SNL S + G H P P P T P
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPG-PHSQSGPGAPMKQAPAPSQPPTSQG-----P 979
Query: 455 PKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPE----PPKTRVSHL 510
PK+ TG + P P K + ++ E L P+ P R
Sbjct: 980 PKS-----------TGQA---PPAPAKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 511 RPEPSETGVSHLRPEPPK-ILVSSLHQAP-PESSVSHLRPE-------PPETGVSHLRPE 561
+ P L EP K +L + L ++P PES+ + E PP +
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTC-TECK 1083
Query: 562 PPKTRMYSLRPEPPDTGVSH-LCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRP 620
+ P P T + LC R S + G P P + P
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS-----GQLGDIRKMPPAPSGPKASPMP 1138
Query: 621 EPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
P E+ S PP+ ++ + + T + E K +S + PP
Sbjct: 1139 VPTESS-SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS-MEKIPPMVTTDQKQE 1196
Query: 681 EPP--ETRVSHLRPEPPETGVSRLHPEPPKTRVSS----LHAEPPESRVSHLCPEPPETG 734
E + + S L+ + P +L PE K R L + P L PE +
Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA 1256
Query: 735 VSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPE-----LPKPRVSSLHLE 789
+ + K +V + E LE RV+ P+T P+ LP SL E
Sbjct: 1257 PEEQKHDLLKSQVQ-IAEEKLEGRVA------PKTVQEGKQPQTKMEGLPSGTPQSLPKE 1309
Query: 790 PPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTME 837
KT + + +PP T + + P KT KE + TSS+ +
Sbjct: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE----KEDDKSDTSSSQQ 1353
Score = 44.7 bits (104), Expect = 5e-04
Identities = 108/469 (23%), Positives = 157/469 (33%), Gaps = 104/469 (22%)
Query: 75 EFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKA-----FVEEVEA-----Q 124
E ++PK GP AD S L S+ P + A+K +E +EA +
Sbjct: 2275 ESVVPKPE--GPVADTVSTD-------LLISEKDPVKKAKKETGNGIILEVLEAYRDKKE 2325
Query: 125 LMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDE-PTEPGKYPC 183
L + + D PP ++ + +G GQEK + P+
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385
Query: 184 GEFSPRP----PETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPP 239
PRP +S PP PP P P PP P PP L PP
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP-------PPPP--------LPPP 2430
Query: 240 ETGVSHLRPEPPKTQVSSLHLEPP-----ETGVSHLYLEPPGTGVSHLC-----PEPPK- 288
+ + P+ T S + P T + L G V+ +C P PPK
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP 2490
Query: 289 ----TRVSHLHREPPETGVPDLCLEP--PKSRVSHLRP---EPSETGVS----------- 328
+ + HR PE P + +P P+ + +P P TG+S
Sbjct: 2491 SSIPSGLVFTHR--PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 329 ---HLHPEPPKTLVSSLHPEPP-------ETGVSHLCPEPPETRV--------------S 364
+ P P L + P ET V P P T S
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 365 PLRQLPPEAGVSHLCPEPPKTRVPPLRPET-PKNGVSPLFPEPPKTRISNLRSEPPKIGV 423
P + L V + P +P +T +G F P T S+ ++ P +
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV-T 2667
Query: 424 SHLCLEPPKTRGSHLRPEPPETGVSHLR----PEPPKTRVSSLHLEPPE 468
L E KT S R P G+S + PEP + ++HLE P+
Sbjct: 2668 QFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP--LALDNIHLEKPQ 2714
Score = 34.7 bits (78), Expect = 0.48
Identities = 65/304 (21%), Positives = 104/304 (34%), Gaps = 51/304 (16%)
Query: 525 EPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE-----PPDTGV 579
+P I+ L Q PP+ P+ G L+ + + S +PE PP TG
Sbjct: 202 KPEGIIKPPLQQQPPKPI-----PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
Query: 580 SHLCP-EPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTR 638
P + P+T + LP + + P + +R E + + P P K
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDAS-------RPQTKQADIVRGESVKPSL----PSPSKPP 305
Query: 639 MYSLRP-EPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPET 697
+ P +PP H +P + PP P L +P + +PP T
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAK----PPAQPSGLTKPLAQQPGTVKPP---VQPPGT 358
Query: 698 GVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLET 757
P P A+PP + P + G L P + + +P P
Sbjct: 359 TKPPAQPLGP--------AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP--- 407
Query: 758 RVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPT 817
+PP V P +P + S P K + ++ P G++ + P
Sbjct: 408 ------AKPPTQQVGTPKPLAQQPGLQS----PAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 818 KTGA 821
KT A
Sbjct: 458 KTSA 461
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 83.6 bits (205), Expect = 9e-16
Identities = 149/681 (21%), Positives = 238/681 (34%), Gaps = 121/681 (17%)
Query: 138 GEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSP---RPPETR 194
GE + P L P+ + G EK+ P +P P G P +P +
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 195 VSCLPP---EPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLR---P 248
PP +PP P+ +P +TG + P + + +PP G + + P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA---QPPGVGKTPAQQPGP 407
Query: 249 EPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCL 308
P TQ + G + PG P P KT V
Sbjct: 408 AKPPTQ---------QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ---------------- 442
Query: 309 EPPKSRVSHLRPEPSETGVSHLHP-EPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLR 367
+P ++ + P +T P +PP L P P + G + P+ P + P +
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 368 Q------LPPEAGVSHLCPEPP-KTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPK 420
Q P + G + P+ P T+ P +P + K P P + S ++P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS---TKPVS 559
Query: 421 IGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
S L+PP S +PP G+ + P + L L PE + C E
Sbjct: 560 QTGSGKPLQPPTVSPS--AKQPPSQGLP--KTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 481 K--DVSHLRPEPPDTGVSH-LC----------------PEPPKTRVSHLRPEPSETGVSH 521
+ P P T V LC P P+ ++ P + + VS
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK-TAPVTTTSAVSK 674
Query: 522 LRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSH 581
P+P + S A P+ +S PEP + PP + +L P S
Sbjct: 675 SSPQPQQ--TSPKKDAAPKQDLSK-APEP--------KKPPPLVKQPTLHGSP-----SA 718
Query: 582 LCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRP--EPPKTRM 639
+PP+ S P P E V E + V+ +P+ P+ ++P + +
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVP---SEQDKAPVADDKPKQPKM----VKPTTDLVSSSS 771
Query: 640 YSLRPEPPNTGVSHLCPE---PPKTRVSSLPPEP-PETGV------SHLCPEPPETR--V 687
+ +P+ P++ V E PP S+ P + P TG S P P +
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 688 SHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV 747
SH P G ++ P K E P+ + + P+P + P PP PR
Sbjct: 832 SHPGPSSESKGQKQVDPVQKK--------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 748 SSLRPEPLETRVSHLRPEPPE 768
++ + P + P+P E
Sbjct: 884 TAGQTVPTPQQ----SPKPQE 900
Score = 50.4 bits (119), Expect = 8e-06
Identities = 169/768 (22%), Positives = 260/768 (33%), Gaps = 127/768 (16%)
Query: 137 LGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVS 196
LG D+ P P P+ KL+ A + P P + +P+ ++
Sbjct: 646 LGGDLAP-------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA- 697
Query: 197 CLPPEPPKTPVSSLRP-----------EPPETGVSHLRPQPPKTQVSSLHLEPPETGVSH 245
PEP K P +P +PPE S +P PPK S+ E + V+
Sbjct: 698 ---PEPKKPPPLVKQPTLHGSPSAKAKQPPEAD-SLSKPAPPKEP--SVPSEQDKAPVAD 751
Query: 246 LRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPE----PPKTRVSHLHREPPET 301
+P+ PK + L + + + P + V E P KT + + P T
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 302 G-----VPDLCLEPPKSR---VSHLRPEPSETGVSHLHP----EPPKTLVSSLHPEPPET 349
G + P S +SH P G + P E PK + + P+P
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 350 GVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPK------------TRVPPLRPETPKN 397
+ P PP R + + +P P+P + T P +P TP+
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVP----TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Query: 398 GVSPL---FPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEP 454
V+ F ++ SNL S + G H P P P T P
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPG-PHSQSGPGAPMKQAPAPSQPPTSQG-----P 979
Query: 455 PKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPE----PPKTRVSHL 510
PK+ TG + P P K + ++ E L P+ P R
Sbjct: 980 PKS-----------TGQA---PPAPAKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 511 RPEPSETGVSHLRPEPPK-ILVSSLHQAP-PESSVSHLRPE-------PPETGVSHLRPE 561
+ P L EP K +L + L ++P PES+ + E PP +
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTC-TECK 1083
Query: 562 PPKTRMYSLRPEPPDTGVSH-LCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRP 620
+ P P T + LC R S + G P P + P
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS-----GQLGDIRKMPPAPSGPKASPMP 1138
Query: 621 EPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
P E+ S PP+ ++ + + T + E K +S + PP
Sbjct: 1139 VPTESS-SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS-MEKIPPMVTTDQKQE 1196
Query: 681 EPP--ETRVSHLRPEPPETGVSRLHPEPPKTRVSS----LHAEPPESRVSHLCPEPPETG 734
E + + S L+ + P +L PE K R L + P L PE +
Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA 1256
Query: 735 VSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPE-----LPKPRVSSLHLE 789
+ + K +V + E LE RV+ P+T P+ LP SL E
Sbjct: 1257 PEEQKHDLLKSQVQ-IAEEKLEGRVA------PKTVQEGKQPQTKMEGLPSGTPQSLPKE 1309
Query: 790 PPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTME 837
KT + + +PP T + + P KT KE + TSS+ +
Sbjct: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE----KEDDKSDTSSSQQ 1353
Score = 44.7 bits (104), Expect = 5e-04
Identities = 108/469 (23%), Positives = 157/469 (33%), Gaps = 104/469 (22%)
Query: 75 EFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKA-----FVEEVEA-----Q 124
E ++PK GP AD S L S+ P + A+K +E +EA +
Sbjct: 2275 ESVVPKPE--GPVADTVSTD-------LLISEKDPVKKAKKETGNGIILEVLEAYRDKKE 2325
Query: 125 LMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDE-PTEPGKYPC 183
L + + D PP ++ + +G GQEK + P+
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385
Query: 184 GEFSPRP----PETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPP 239
PRP +S PP PP P P PP P PP L PP
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP-------PPPP--------LPPP 2430
Query: 240 ETGVSHLRPEPPKTQVSSLHLEPP-----ETGVSHLYLEPPGTGVSHLC-----PEPPK- 288
+ + P+ T S + P T + L G V+ +C P PPK
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP 2490
Query: 289 ----TRVSHLHREPPETGVPDLCLEP--PKSRVSHLRP---EPSETGVS----------- 328
+ + HR PE P + +P P+ + +P P TG+S
Sbjct: 2491 SSIPSGLVFTHR--PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 329 ---HLHPEPPKTLVSSLHPEPP-------ETGVSHLCPEPPETRV--------------S 364
+ P P L + P ET V P P T S
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 365 PLRQLPPEAGVSHLCPEPPKTRVPPLRPET-PKNGVSPLFPEPPKTRISNLRSEPPKIGV 423
P + L V + P +P +T +G F P T S+ ++ P +
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV-T 2667
Query: 424 SHLCLEPPKTRGSHLRPEPPETGVSHLR----PEPPKTRVSSLHLEPPE 468
L E KT S R P G+S + PEP + ++HLE P+
Sbjct: 2668 QFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP--LALDNIHLEKPQ 2714
Score = 34.7 bits (78), Expect = 0.48
Identities = 65/304 (21%), Positives = 104/304 (34%), Gaps = 51/304 (16%)
Query: 525 EPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE-----PPDTGV 579
+P I+ L Q PP+ P+ G L+ + + S +PE PP TG
Sbjct: 202 KPEGIIKPPLQQQPPKPI-----PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
Query: 580 SHLCP-EPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTR 638
P + P+T + LP + + P + +R E + + P P K
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDAS-------RPQTKQADIVRGESVKPSL----PSPSKPP 305
Query: 639 MYSLRP-EPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPET 697
+ P +PP H +P + PP P L +P + +PP T
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAK----PPAQPSGLTKPLAQQPGTVKPP---VQPPGT 358
Query: 698 GVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLET 757
P P A+PP + P + G L P + + +P P
Sbjct: 359 TKPPAQPLGP--------AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP--- 407
Query: 758 RVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPT 817
+PP V P +P + S P K + ++ P G++ + P
Sbjct: 408 ------AKPPTQQVGTPKPLAQQPGLQS----PAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 818 KTGA 821
KT A
Sbjct: 458 KTSA 461
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 82.0 bits (201), Expect = 3e-15
Identities = 135/487 (27%), Positives = 172/487 (35%), Gaps = 58/487 (11%)
Query: 298 PPETGV-PDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCP 356
P ET P + LEPP + P ET + +S+ E E V+ + P
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVA-VMP 234
Query: 357 EPPETRVSPLRQLPPEAGVSHLCP--EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNL 414
EP T++ P + + EP T + ++ V PEP K +
Sbjct: 235 EPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIMLV-- 292
Query: 415 RSEPPKIGVSHLCLEPPKTR--GSHLRPEP-PETGVSHLRPEPPKTRVSSLHLE------ 465
EPP V LEP +T S E PE S P + + +L L
Sbjct: 293 --EPPVAKV----LEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDV 346
Query: 466 PPETGVSHLC-----PEPPEKDVSHLR----------PEPPDTGVSHLCPEPPKTRVSHL 510
P E S + PE P+ L+ P PP T + L PP T V L
Sbjct: 347 PSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSMPEL-QGPPVTPVLEL 405
Query: 511 RPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSL 570
P PS T V L P P V L PP ++V L P P T V L E P S+
Sbjct: 406 -PGPSATPVPEL-PGPLSTPVPEL-PGPPATAVPEL-PGPSVTPVPQLSQELPGLPAPSM 461
Query: 571 RPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHL 630
EPP PEPP LP P T L PE P V+ E P T
Sbjct: 462 GLEPPQE-----VPEPP-VMAQELPGLPLVTAAVEL-PEQPAVTVAMELTEQPVTTTELE 514
Query: 631 RP----------EPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
+P P T L +P T V L +P T LP +P TGV L
Sbjct: 515 QPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPG 574
Query: 681 EPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRP 740
P TR L +P TG L + + L +P TGV L
Sbjct: 575 LPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPG 634
Query: 741 EPPKPRV 747
+P P +
Sbjct: 635 QPGAPEL 641
Score = 78.6 bits (192), Expect = 3e-14
Identities = 138/512 (26%), Positives = 186/512 (36%), Gaps = 55/512 (10%)
Query: 190 PPETRVS-CLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVS----SLHLEPPETGVS 244
P ET S + EPP + P ET L+P ++S S+ E E V+
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILET----LKPATKTAELSVVSTSVISEQSEQSVA 231
Query: 245 HLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVP 304
+ PEP T++ P + L L+ V+ K+ + + PE
Sbjct: 232 -VMPEPSMTKILDSFAAAP-VPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPS-K 288
Query: 305 DLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVS 364
+ +EPP ++V EPSET V + E P + ++PEP S P + +
Sbjct: 289 IMLVEPPVAKVL----EPSETLV--VSSETP----TEVYPEP---STSTTMDFPESSAIE 335
Query: 365 PLR------QLPPEAGVSHLC-----PEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISN 413
LR +P E S + PE PKT L+ + + + P PP T +
Sbjct: 336 ALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAME--LPGPPATSMPE 393
Query: 414 LRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSH 473
L+ PP V L L P P P T V L P PP T V L P T V
Sbjct: 394 LQG-PPVTPV--LELPGPSATPVPELPGPLSTPVPEL-PGPPATAVPELP-GPSVTPVPQ 448
Query: 474 LCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSS 533
L E P + EPP PEPP L P T L +P +
Sbjct: 449 LSQELPGLPAPSMGLEPPQE-----VPEPP-VMAQELPGLPLVTAAVELPEQPAVTVAME 502
Query: 534 LHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSS 593
L + P + + L T V H P T L +P T V L +P T
Sbjct: 503 LTEQPV--TTTELEQPVGMTTVEH-PGHPEVTTATGLLGQPEATMVLELPGQPVATTALE 559
Query: 594 LPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSH 653
LP +P TGV L P TR L +P TG L + G
Sbjct: 560 LPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALE 619
Query: 654 LCPEPPKTRVSSLPPEPPETGVSHLCPEPPET 685
L +P T V LP +P G L +P T
Sbjct: 620 LLGQPLATGVLELPGQP---GAPELPGQPVAT 648
Score = 57.8 bits (138), Expect = 5e-08
Identities = 92/304 (30%), Positives = 118/304 (38%), Gaps = 36/304 (11%)
Query: 501 EPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGV--SHL 558
EPP + P ET + ++ +S+ E SV+ + PEP T + S
Sbjct: 188 EPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVA-VMPEPSMTKILDSFA 246
Query: 559 RPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL 618
P T + EP T + V S PEP + + EPP +V
Sbjct: 247 AAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKI----MLVEPPVAKVL-- 300
Query: 619 RPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHL 678
EP ET V + E P T +Y PEP +T + PE LP +P + V
Sbjct: 301 --EPSETLV--VSSETP-TEVY---PEP-STSTTMDFPESSAIEALRLPEQPVD--VPSE 349
Query: 679 CPEPPETRVSHLRPEPPETGVSRLH----------PEPPKTRVSSLHAEPPESRVSHLCP 728
+ TR L PE P+T L P PP T + L PP + V L P
Sbjct: 350 IADSSMTRPQEL-PELPKTTALELQESSVASAMELPGPPATSMPELQG-PPVTPVLEL-P 406
Query: 729 EPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHL 788
P T V L P P V L P P T V L P P T V L ELP S+ L
Sbjct: 407 GPSATPVPEL-PGPLSTPVPEL-PGPPATAVPEL-PGPSVTPVPQLSQELPGLPAPSMGL 463
Query: 789 EPPK 792
EPP+
Sbjct: 464 EPPQ 467
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/217 (26%), Positives = 75/217 (34%), Gaps = 26/217 (11%)
Query: 188 PRPPETRVSCLPPEPPKTPVSSLRPEPPE------------------TGVSHLRPQPPKT 229
P P T V L E P P S+ EPP+ T L QP T
Sbjct: 439 PGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVT 498
Query: 230 QVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPE-TGVSHLYLEPPGTGVSHLCPEPPK 288
L +P V+ E P + H PE T + L +P T V L +P
Sbjct: 499 VAMELTEQP----VTTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVA 554
Query: 289 TRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPE 348
T L +P TGVP+L P +R L +P TG L +
Sbjct: 555 TTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGA 614
Query: 349 TGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKT 385
G L +P T V +LP + G L +P T
Sbjct: 615 AGALELLGQPLATGV---LELPGQPGAPELPGQPVAT 648
Score = 43.9 bits (102), Expect = 8e-04
Identities = 59/217 (27%), Positives = 84/217 (38%), Gaps = 55/217 (25%)
Query: 589 TRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPN 648
T +PP PPE EPP + P PPE EPP T L PE P
Sbjct: 1141 TEAYMVPPLPPE--------EPPT-----MPPLPPE--------EPPMTP--PLPPEEPP 1177
Query: 649 TGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPK 708
G + + T ++ P E P + P E VS +PEPP + +
Sbjct: 1178 EGPALPTEQSALTAENTWPTEVPSS--------PSEESVS--QPEPPVS----------Q 1217
Query: 709 TRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPE 768
+ +S A P + VS P + + PEPP SS+ P+E+ V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAV--------- 1268
Query: 769 TGVSHLHPELPKPRVSSLHLE-PPKTRRVSSLRLEPP 804
V+ H +P+ V+ + E P + + L EPP
Sbjct: 1269 --VAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPP 1303
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/172 (30%), Positives = 66/172 (38%), Gaps = 21/172 (12%)
Query: 447 VSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTR 506
V L PE P T EPP T P PPE+ PE P T
Sbjct: 1146 VPPLPPEEPPTMPPLPPEEPPMTP-----PLPPEEP-----PEGPALPTEQSALTAENTW 1195
Query: 507 VSHLRPEPSETGVSHLRPEPP--KILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPK 564
+ + PSE VS +PEPP + +S P + SVS P + + PEPP
Sbjct: 1196 PTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPP 1253
Query: 565 TRMYSLRPEPPDTGV----SHLCPEPPKT-RVSSLPPEPPETGVSHLCPEPP 611
S+ P ++ V + PE P T VS P E V L EPP
Sbjct: 1254 EPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTV--LASEPP 1303
Score = 41.2 bits (95), Expect = 0.005
Identities = 67/238 (28%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 565 TRMYSLRPEPPDTG--VSHLCPEPPKTRVSSLPPEPPE-----TGVSHLCPEPPETRVSH 617
T Y + P PP+ + L PE P P EPPE T S L E T +
Sbjct: 1141 TEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAE--NTWPTE 1198
Query: 618 LRPEPPETGVSHLRPEPPKTRMYSLRPE--PPNTGVSHLCPEPPKTRVSSLPPEPPETGV 675
+ P E VS +PEPP ++ P P + VS P + + PEPP
Sbjct: 1199 VPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE 1256
Query: 676 SHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGV 735
S + P E+ V V+ H P+ V+ + +E P + EP
Sbjct: 1257 SSITLTPVESAV-----------VAEEHEVVPERPVTCMVSETPA-----MSAEP----- 1295
Query: 736 SHLRPEPPKPRVSSLRPEPLET-RVS-HLRPEPPETGVSHLHPELPKPRVSSLHLEPP 791
+ L EPP V S E ++ R S H+ E S L P + P ++ LEPP
Sbjct: 1296 TVLASEPP---VMSETAETFDSMRASGHV---ASEVSTSLLVPAVTTPVLAESILEPP 1347
Score = 39.7 bits (91), Expect = 0.015
Identities = 45/141 (31%), Positives = 56/141 (39%), Gaps = 18/141 (12%)
Query: 172 TDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQV 231
TD TE P P P T P EPP TP L PE P G + Q T
Sbjct: 1137 TDTYTEAYMVP--PLPPEEPPTMPPLPPEEPPMTP--PLPPEEPPEGPALPTEQSALTAE 1192
Query: 232 SSLHLE----PPETGVSHLRPEPP--KTQVSSLHLEPPETGVSHLYLEPPGTGVSHLC-- 283
++ E P E VS +PEPP ++++S P + VS P VS
Sbjct: 1193 NTWPTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVS---ASDPSVLVSEAAVT 1247
Query: 284 -PEPPKTRVSHLHREPPETGV 303
PEPP S + P E+ V
Sbjct: 1248 VPEPPPEPESSITLTPVESAV 1268
Score = 39.7 bits (91), Expect = 0.015
Identities = 83/320 (25%), Positives = 111/320 (34%), Gaps = 38/320 (11%)
Query: 243 VSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETG 302
V L PE P T EPP T L E P G P P + + T
Sbjct: 1146 VPPLPPEEPPTMPPLPPEEPPMT--PPLPPEEPPEG-----PALPTEQSALTAENTWPTE 1198
Query: 303 VPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETR 362
VP P + VS P S++ +S P VS+ P + + PEPP
Sbjct: 1199 VPS---SPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEP 1255
Query: 363 VSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIG 422
S + P E+ V + V P RP T +P P L SEPP +
Sbjct: 1256 ESSITLTPVESAV-----VAEEHEVVPERPVTCMVSETPAMSAEPTV----LASEPPVMS 1306
Query: 423 VSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKD 482
+ + + G H+ E S L P ++ LEPP P
Sbjct: 1307 ETAETFDSMRASG-HV---ASEVSTSLLVPAVTTPVLAESILEPPAMAA------PESSA 1356
Query: 483 VSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESS 542
++ L S + V+ L EPS V PEPP ++ + P
Sbjct: 1357 MAVLESSAVTVLESSTVTVLESSTVTVL--EPSVVTV----PEPP-VVAEPDYVTIPVPV 1409
Query: 543 VSHLRPEPP--ETGVSHLRP 560
VS L P P E VS L+P
Sbjct: 1410 VSALEPSVPVLEPAVSVLQP 1429
Score = 36.2 bits (82), Expect = 0.16
Identities = 31/116 (26%), Positives = 40/116 (34%)
Query: 171 TTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQ 230
T + P P +P T V LP +P T L +P TGV L P T+
Sbjct: 521 TVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPGLPSATR 580
Query: 231 VSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEP 286
L +P TG L + G L +P TGV L +P
Sbjct: 581 ALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPGQP 636
Score = 36.2 bits (82), Expect = 0.16
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 40/204 (19%)
Query: 472 SHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILV 531
+++ P P ++ + P PP+ EPP T P P E PE P +
Sbjct: 1143 AYMVPPLPPEEPPTMPPLPPE--------EPPMTP-----PLPPEEP-----PEGPALPT 1184
Query: 532 SSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE--PPDTGVSHLCPEPPKT 589
+ + + P E VS +PEPP ++ P P D VS P +
Sbjct: 1185 EQSALTAENTWPTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVS 1242
Query: 590 RVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNT 649
+ PEPP S + P E+ V E + PE P T M S P
Sbjct: 1243 EAAVTVPEPPPEPESSITLTPVESAVVAEEHE--------VVPERPVTCMVSETPA---- 1290
Query: 650 GVSHLCPEPPKTRVSSLPPEPPET 673
+ EP T ++S PP ET
Sbjct: 1291 ----MSAEP--TVLASEPPVMSET 1308
Score = 31.2 bits (69), Expect = 5.3
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 24/194 (12%)
Query: 70 VCRRDEFLLPKISLRGPQADPKSR-KKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTK 128
V RR F + + LR + + R + +++ S P R +++ + + K
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAK 2063
Query: 129 -HPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFS 187
+ AM G +PP+L KP P +E+ + + T +E TE C + +
Sbjct: 2064 ANAAAMCAKAGVPLPPNL-----KPAPPPT-IEEKVAKKSGGATIEELTEK----CKQIA 2113
Query: 188 PRPPETRVSCLPP--------EPP--KTPVSSLRPEPP--ETGVSHLRPQPPKTQVSSLH 235
+ V P EPP P P+P ++ +P PPK+QV+
Sbjct: 2114 QSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTK 2173
Query: 236 LEPPETGVSHLRPE 249
P +G H + E
Sbjct: 2174 EFPVSSGSQHRKKE 2187
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 82.0 bits (201), Expect = 3e-15
Identities = 135/487 (27%), Positives = 172/487 (35%), Gaps = 58/487 (11%)
Query: 298 PPETGV-PDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCP 356
P ET P + LEPP + P ET + +S+ E E V+ + P
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVA-VMP 234
Query: 357 EPPETRVSPLRQLPPEAGVSHLCP--EPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNL 414
EP T++ P + + EP T + ++ V PEP K +
Sbjct: 235 EPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIMLV-- 292
Query: 415 RSEPPKIGVSHLCLEPPKTR--GSHLRPEP-PETGVSHLRPEPPKTRVSSLHLE------ 465
EPP V LEP +T S E PE S P + + +L L
Sbjct: 293 --EPPVAKV----LEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDV 346
Query: 466 PPETGVSHLC-----PEPPEKDVSHLR----------PEPPDTGVSHLCPEPPKTRVSHL 510
P E S + PE P+ L+ P PP T + L PP T V L
Sbjct: 347 PSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSMPEL-QGPPVTPVLEL 405
Query: 511 RPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSL 570
P PS T V L P P V L PP ++V L P P T V L E P S+
Sbjct: 406 -PGPSATPVPEL-PGPLSTPVPEL-PGPPATAVPEL-PGPSVTPVPQLSQELPGLPAPSM 461
Query: 571 RPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHL 630
EPP PEPP LP P T L PE P V+ E P T
Sbjct: 462 GLEPPQE-----VPEPP-VMAQELPGLPLVTAAVEL-PEQPAVTVAMELTEQPVTTTELE 514
Query: 631 RP----------EPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
+P P T L +P T V L +P T LP +P TGV L
Sbjct: 515 QPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPG 574
Query: 681 EPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRP 740
P TR L +P TG L + + L +P TGV L
Sbjct: 575 LPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPG 634
Query: 741 EPPKPRV 747
+P P +
Sbjct: 635 QPGAPEL 641
Score = 78.6 bits (192), Expect = 3e-14
Identities = 138/512 (26%), Positives = 186/512 (36%), Gaps = 55/512 (10%)
Query: 190 PPETRVS-CLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVS----SLHLEPPETGVS 244
P ET S + EPP + P ET L+P ++S S+ E E V+
Sbjct: 176 PSETNESPAVVLEPPVVSMEVSEPHILET----LKPATKTAELSVVSTSVISEQSEQSVA 231
Query: 245 HLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVP 304
+ PEP T++ P + L L+ V+ K+ + + PE
Sbjct: 232 -VMPEPSMTKILDSFAAAP-VPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPS-K 288
Query: 305 DLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVS 364
+ +EPP ++V EPSET V + E P + ++PEP S P + +
Sbjct: 289 IMLVEPPVAKVL----EPSETLV--VSSETP----TEVYPEP---STSTTMDFPESSAIE 335
Query: 365 PLR------QLPPEAGVSHLC-----PEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISN 413
LR +P E S + PE PKT L+ + + + P PP T +
Sbjct: 336 ALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAME--LPGPPATSMPE 393
Query: 414 LRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSH 473
L+ PP V L L P P P T V L P PP T V L P T V
Sbjct: 394 LQG-PPVTPV--LELPGPSATPVPELPGPLSTPVPEL-PGPPATAVPELP-GPSVTPVPQ 448
Query: 474 LCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSS 533
L E P + EPP PEPP L P T L +P +
Sbjct: 449 LSQELPGLPAPSMGLEPPQE-----VPEPP-VMAQELPGLPLVTAAVELPEQPAVTVAME 502
Query: 534 LHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSS 593
L + P + + L T V H P T L +P T V L +P T
Sbjct: 503 LTEQPV--TTTELEQPVGMTTVEH-PGHPEVTTATGLLGQPEATMVLELPGQPVATTALE 559
Query: 594 LPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSH 653
LP +P TGV L P TR L +P TG L + G
Sbjct: 560 LPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALE 619
Query: 654 LCPEPPKTRVSSLPPEPPETGVSHLCPEPPET 685
L +P T V LP +P G L +P T
Sbjct: 620 LLGQPLATGVLELPGQP---GAPELPGQPVAT 648
Score = 57.8 bits (138), Expect = 5e-08
Identities = 92/304 (30%), Positives = 118/304 (38%), Gaps = 36/304 (11%)
Query: 501 EPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGV--SHL 558
EPP + P ET + ++ +S+ E SV+ + PEP T + S
Sbjct: 188 EPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVA-VMPEPSMTKILDSFA 246
Query: 559 RPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL 618
P T + EP T + V S PEP + + EPP +V
Sbjct: 247 AAPVPTTTLVLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKI----MLVEPPVAKVL-- 300
Query: 619 RPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHL 678
EP ET V + E P T +Y PEP +T + PE LP +P + V
Sbjct: 301 --EPSETLV--VSSETP-TEVY---PEP-STSTTMDFPESSAIEALRLPEQPVD--VPSE 349
Query: 679 CPEPPETRVSHLRPEPPETGVSRLH----------PEPPKTRVSSLHAEPPESRVSHLCP 728
+ TR L PE P+T L P PP T + L PP + V L P
Sbjct: 350 IADSSMTRPQEL-PELPKTTALELQESSVASAMELPGPPATSMPELQG-PPVTPVLEL-P 406
Query: 729 EPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHL 788
P T V L P P V L P P T V L P P T V L ELP S+ L
Sbjct: 407 GPSATPVPEL-PGPLSTPVPEL-PGPPATAVPEL-PGPSVTPVPQLSQELPGLPAPSMGL 463
Query: 789 EPPK 792
EPP+
Sbjct: 464 EPPQ 467
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/217 (26%), Positives = 75/217 (34%), Gaps = 26/217 (11%)
Query: 188 PRPPETRVSCLPPEPPKTPVSSLRPEPPE------------------TGVSHLRPQPPKT 229
P P T V L E P P S+ EPP+ T L QP T
Sbjct: 439 PGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVT 498
Query: 230 QVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPE-TGVSHLYLEPPGTGVSHLCPEPPK 288
L +P V+ E P + H PE T + L +P T V L +P
Sbjct: 499 VAMELTEQP----VTTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVA 554
Query: 289 TRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPE 348
T L +P TGVP+L P +R L +P TG L +
Sbjct: 555 TTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGA 614
Query: 349 TGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKT 385
G L +P T V +LP + G L +P T
Sbjct: 615 AGALELLGQPLATGV---LELPGQPGAPELPGQPVAT 648
Score = 43.9 bits (102), Expect = 8e-04
Identities = 59/217 (27%), Positives = 84/217 (38%), Gaps = 55/217 (25%)
Query: 589 TRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPN 648
T +PP PPE EPP + P PPE EPP T L PE P
Sbjct: 1141 TEAYMVPPLPPE--------EPPT-----MPPLPPE--------EPPMTP--PLPPEEPP 1177
Query: 649 TGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPK 708
G + + T ++ P E P + P E VS +PEPP + +
Sbjct: 1178 EGPALPTEQSALTAENTWPTEVPSS--------PSEESVS--QPEPPVS----------Q 1217
Query: 709 TRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPE 768
+ +S A P + VS P + + PEPP SS+ P+E+ V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAV--------- 1268
Query: 769 TGVSHLHPELPKPRVSSLHLE-PPKTRRVSSLRLEPP 804
V+ H +P+ V+ + E P + + L EPP
Sbjct: 1269 --VAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPP 1303
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/172 (30%), Positives = 66/172 (38%), Gaps = 21/172 (12%)
Query: 447 VSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTR 506
V L PE P T EPP T P PPE+ PE P T
Sbjct: 1146 VPPLPPEEPPTMPPLPPEEPPMTP-----PLPPEEP-----PEGPALPTEQSALTAENTW 1195
Query: 507 VSHLRPEPSETGVSHLRPEPP--KILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPK 564
+ + PSE VS +PEPP + +S P + SVS P + + PEPP
Sbjct: 1196 PTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPP 1253
Query: 565 TRMYSLRPEPPDTGV----SHLCPEPPKT-RVSSLPPEPPETGVSHLCPEPP 611
S+ P ++ V + PE P T VS P E V L EPP
Sbjct: 1254 EPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTV--LASEPP 1303
Score = 41.2 bits (95), Expect = 0.005
Identities = 67/238 (28%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 565 TRMYSLRPEPPDTG--VSHLCPEPPKTRVSSLPPEPPE-----TGVSHLCPEPPETRVSH 617
T Y + P PP+ + L PE P P EPPE T S L E T +
Sbjct: 1141 TEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAE--NTWPTE 1198
Query: 618 LRPEPPETGVSHLRPEPPKTRMYSLRPE--PPNTGVSHLCPEPPKTRVSSLPPEPPETGV 675
+ P E VS +PEPP ++ P P + VS P + + PEPP
Sbjct: 1199 VPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE 1256
Query: 676 SHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGV 735
S + P E+ V V+ H P+ V+ + +E P + EP
Sbjct: 1257 SSITLTPVESAV-----------VAEEHEVVPERPVTCMVSETPA-----MSAEP----- 1295
Query: 736 SHLRPEPPKPRVSSLRPEPLET-RVS-HLRPEPPETGVSHLHPELPKPRVSSLHLEPP 791
+ L EPP V S E ++ R S H+ E S L P + P ++ LEPP
Sbjct: 1296 TVLASEPP---VMSETAETFDSMRASGHV---ASEVSTSLLVPAVTTPVLAESILEPP 1347
Score = 39.7 bits (91), Expect = 0.015
Identities = 45/141 (31%), Positives = 56/141 (39%), Gaps = 18/141 (12%)
Query: 172 TDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQV 231
TD TE P P P T P EPP TP L PE P G + Q T
Sbjct: 1137 TDTYTEAYMVP--PLPPEEPPTMPPLPPEEPPMTP--PLPPEEPPEGPALPTEQSALTAE 1192
Query: 232 SSLHLE----PPETGVSHLRPEPP--KTQVSSLHLEPPETGVSHLYLEPPGTGVSHLC-- 283
++ E P E VS +PEPP ++++S P + VS P VS
Sbjct: 1193 NTWPTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVS---ASDPSVLVSEAAVT 1247
Query: 284 -PEPPKTRVSHLHREPPETGV 303
PEPP S + P E+ V
Sbjct: 1248 VPEPPPEPESSITLTPVESAV 1268
Score = 39.7 bits (91), Expect = 0.015
Identities = 83/320 (25%), Positives = 111/320 (34%), Gaps = 38/320 (11%)
Query: 243 VSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETG 302
V L PE P T EPP T L E P G P P + + T
Sbjct: 1146 VPPLPPEEPPTMPPLPPEEPPMT--PPLPPEEPPEG-----PALPTEQSALTAENTWPTE 1198
Query: 303 VPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETR 362
VP P + VS P S++ +S P VS+ P + + PEPP
Sbjct: 1199 VPS---SPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEP 1255
Query: 363 VSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIG 422
S + P E+ V + V P RP T +P P L SEPP +
Sbjct: 1256 ESSITLTPVESAV-----VAEEHEVVPERPVTCMVSETPAMSAEPTV----LASEPPVMS 1306
Query: 423 VSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKD 482
+ + + G H+ E S L P ++ LEPP P
Sbjct: 1307 ETAETFDSMRASG-HV---ASEVSTSLLVPAVTTPVLAESILEPPAMAA------PESSA 1356
Query: 483 VSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESS 542
++ L S + V+ L EPS V PEPP ++ + P
Sbjct: 1357 MAVLESSAVTVLESSTVTVLESSTVTVL--EPSVVTV----PEPP-VVAEPDYVTIPVPV 1409
Query: 543 VSHLRPEPP--ETGVSHLRP 560
VS L P P E VS L+P
Sbjct: 1410 VSALEPSVPVLEPAVSVLQP 1429
Score = 36.2 bits (82), Expect = 0.16
Identities = 31/116 (26%), Positives = 40/116 (34%)
Query: 171 TTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQ 230
T + P P +P T V LP +P T L +P TGV L P T+
Sbjct: 521 TVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPGLPSATR 580
Query: 231 VSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEP 286
L +P TG L + G L +P TGV L +P
Sbjct: 581 ALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPGQP 636
Score = 36.2 bits (82), Expect = 0.16
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 40/204 (19%)
Query: 472 SHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILV 531
+++ P P ++ + P PP+ EPP T P P E PE P +
Sbjct: 1143 AYMVPPLPPEEPPTMPPLPPE--------EPPMTP-----PLPPEEP-----PEGPALPT 1184
Query: 532 SSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE--PPDTGVSHLCPEPPKT 589
+ + + P E VS +PEPP ++ P P D VS P +
Sbjct: 1185 EQSALTAENTWPTEVPSSPSEESVS--QPEPPVSQSEISEPSAVPTDYSVSASDPSVLVS 1242
Query: 590 RVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNT 649
+ PEPP S + P E+ V E + PE P T M S P
Sbjct: 1243 EAAVTVPEPPPEPESSITLTPVESAVVAEEHE--------VVPERPVTCMVSETPA---- 1290
Query: 650 GVSHLCPEPPKTRVSSLPPEPPET 673
+ EP T ++S PP ET
Sbjct: 1291 ----MSAEP--TVLASEPPVMSET 1308
Score = 31.2 bits (69), Expect = 5.3
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 24/194 (12%)
Query: 70 VCRRDEFLLPKISLRGPQADPKSR-KKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTK 128
V RR F + + LR + + R + +++ S P R +++ + + K
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAK 2063
Query: 129 -HPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFS 187
+ AM G +PP+L KP P +E+ + + T +E TE C + +
Sbjct: 2064 ANAAAMCAKAGVPLPPNL-----KPAPPPT-IEEKVAKKSGGATIEELTEK----CKQIA 2113
Query: 188 PRPPETRVSCLPP--------EPP--KTPVSSLRPEPP--ETGVSHLRPQPPKTQVSSLH 235
+ V P EPP P P+P ++ +P PPK+QV+
Sbjct: 2114 QSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTK 2173
Query: 236 LEPPETGVSHLRPE 249
P +G H + E
Sbjct: 2174 EFPVSSGSQHRKKE 2187
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 81.6 bits (200), Expect = 3e-15
Identities = 155/611 (25%), Positives = 198/611 (32%), Gaps = 121/611 (19%)
Query: 154 DPERKLEDA--GSCEGQEKTTDEP---------TEPGKYPCGEFSPRPPETRVSCLPPEP 202
+ ER++++ +C + K DE EP P +P PP LP P
Sbjct: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPP 532
Query: 203 PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP 262
P S+ PET PP + + T VS T S P
Sbjct: 533 APPPASA---PTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSG-GGSTSSTSSGSFEASP 588
Query: 263 PETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEP 322
E + P G PEPP+ PP T P +EP + R P
Sbjct: 589 VEPQL------PSKEG-----PEPPE-------EVPPPTTPPVPKVEPKGDGIGPTRQPP 630
Query: 323 SETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEP 382
S+ G+ + P+ K+L + E L+Q H
Sbjct: 631 SQ-GLGY--PKYQKSLPPRFQRQQQE---------------QLLKQQQQHQWQQHQQGSA 672
Query: 383 PKTRVPPLRPETPKNGVSPLF---PEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLR 439
P T VPP P+ G P P PPK PP + PP
Sbjct: 673 PPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPM--------PPMNFDPRWM 724
Query: 440 PEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLC 499
PP L+ PP L PP S L P D EP D +
Sbjct: 725 MIPPYVDPRLLQGRPP------LDFYPPGVHPSGLVPRE-RSDSGGSSSEPFDRHAPAML 777
Query: 500 PEPPKTRVSHLRPEPSETG-VSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHL 558
E V P+ + G V P P+ L S L QA E PP +
Sbjct: 778 RERGTPPVD---PKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPP------V 828
Query: 559 RPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL 618
P PP Y P P+ G P PP +S P E P G L P V+ +
Sbjct: 829 PPPPPYLASY---PGFPENGA----PGPP---ISRFPLEEP--GPRPLPWPPGSDEVAKI 876
Query: 619 RPEPPETGVSHLRPEPPKTRMYSLR-PEP---PNTGVSHLCPEPPKTRVSSLPPEPPETG 674
+ PP + EPPK L PE P GV PP PP
Sbjct: 877 QTPPP-------KKEPPKEETAQLTGPEAGRKPARGVGSGGQGPP-------PPRRESRT 922
Query: 675 VSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETG 734
+ P P +R R PPE P P R + PP ++V L P+P E G
Sbjct: 923 ETRWGPRPGSSR----RGIPPE------EPGAPPRRAGPIKKPPPPTKVEELPPKPLEQG 972
Query: 735 VSHLRPEPPKP 745
P+PPKP
Sbjct: 973 DE--TPKPPKP 981
Score = 68.2 bits (165), Expect = 4e-11
Identities = 165/717 (23%), Positives = 220/717 (30%), Gaps = 139/717 (19%)
Query: 161 DAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVS 220
D+ S G+E+ + + G P E PP P + RP E G
Sbjct: 360 DSQSASGEERPPEADGKKGNSPNSE-------------PPTPKTAWAETSRPPETEPG-- 404
Query: 221 HLRPQPPKTQVSSLHLEP----------PETGVSHLRPEPPKTQVSSLHLEPPETGVSHL 270
P PK + H P P+ G +P P+ + + ++ S +
Sbjct: 405 ---PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSS-SEI 460
Query: 271 YLEPPGTG------VSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSE 324
L + E L R + G PD L+ EP+
Sbjct: 461 SLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPD----------KRLKAEPAA 510
Query: 325 TGVSHLHPEPPKTLVSSLH--PEPPETGVSHLCPEPPETRVSPLRQLPPEAGV------- 375
+ P PP + L P PP EP E +P Q P GV
Sbjct: 511 PPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLV 570
Query: 376 ----SHLCPEPPKTRVPPLRPETP-KNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEP 430
S P+ P+ P K G PEPP+ PK+
Sbjct: 571 SGGGSTSSTSSGSFEASPVEPQLPSKEG-----PEPPEEVPPPTTPPVPKV--------E 617
Query: 431 PKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEP 490
PK G +PP G+ + P+ K+ + E L + + H +
Sbjct: 618 PKGDGIGPTRQPPSQGLGY--PKYQKSLPPRFQRQQQE---QLLKQQQQHQWQQHQQGSA 672
Query: 491 PDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPE- 549
P T V P PP+ P P P PPK L PP + P
Sbjct: 673 PPTPVP---PSPPQPVTLGAVPAPQAP------PPPPKALYPGALGRPPPMPPMNFDPRW 723
Query: 550 ---PPETGVSHL--RPE----PPKTRMYSLRP-EPPDTGVSHLCP----EPPKTRVSSLP 595
PP L RP PP L P E D+G S P P R P
Sbjct: 724 MMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP 783
Query: 596 PEPPETG----VSHLCPEPPETRVSHLRPEPPE------TGVSHLRPEPPKTRMYSLRPE 645
P P+ V P P S LR E + + P PP Y PE
Sbjct: 784 PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPE 843
Query: 646 --PPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP---EPPETRVSHLRPEPPETGVS 700
P +S E P R PP E P EPP+ + L PE G
Sbjct: 844 NGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG--PEAG-- 899
Query: 701 RLHPEPPKTRVSSLHAEPPESRVSHL------CPEPPETGVSHLRPEPPKPRVSSLRPEP 754
+P + S PP R S P G+ P P R ++ P
Sbjct: 900 ---RKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPP 956
Query: 755 LETRVSHLRPEPPETGVSHLHPELPKP-RVSSLHLEPPKTRRVSSLRLEPPKTGRVS 810
T+V L P+P E G P P P +++ L PK E P G +S
Sbjct: 957 PPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPK---------ETPPNGNLS 1004
Score = 48.5 bits (114), Expect = 3e-05
Identities = 142/594 (23%), Positives = 197/594 (33%), Gaps = 94/594 (15%)
Query: 176 TEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVS---HLRPQPPKTQVS 232
T PG +P P P+ P P P + P+ +G+S H + P V
Sbjct: 1491 TAPGGHP--RHKPGLPQA-----PQGPSPRPPTRYEPQRVNSGLSSDPHF--EEPGPMVR 1541
Query: 233 SLHLEPPET-GVSHLRPE-----PPKTQVSSLHLEPPETGVSHLYLEPPG---------T 277
+ P ++ GVS P+ P K ++ PP L +P G T
Sbjct: 1542 GVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDT 1601
Query: 278 GVSHLCPEPPKTRVSHLHREPPETGVPDLCLEP--PKSRVSHLRPEPSETGVSHLHPEPP 335
G L P + R+ + +EP P V+ S++GV L +
Sbjct: 1602 GTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGDSQ 1660
Query: 336 KTLVSSLHPEPPETGVSHLCPEPPETR--VSPLRQLPPEAGVSHLCPEPPKTRVPPLRPE 393
+ P+ G+ PP+ SPL +P C PP + P P
Sbjct: 1661 VSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVP--------CEGPPGSEPPRRPPP 1712
Query: 394 TPKNGVSPLFPEP---PKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPP-ETGVSH 449
P +G P P I RS+ G EP R SH RP PP + G S
Sbjct: 1713 APHDGDRKELPREQPLPPGPIGTERSQRTDRGT-----EPGPIRPSH-RPGPPVQFGTSD 1766
Query: 450 LRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSH 509
+ SL E E S P +D L + + P+ H
Sbjct: 1767 KDSDLRLVVGDSLKAEK-ELTASVTEAIPVSRDWELL-----PSAAASAEPQSKNLDSGH 1820
Query: 510 LRPEPSETGVSHLRPEPPKILVSSLHQAPPESSV-------SHLRPEPP--ETGVSHLRP 560
PEPS +G L PE + S A P SS S L P G L P
Sbjct: 1821 CVPEPSSSG-QRLYPE---VFYGS---AGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHP 1873
Query: 561 EPPKTRMYSLRPEPPDTGVSHLCPEPP--------KTRVSSLP------PEPPETGVSHL 606
+ P PP +S L + T + LP P P
Sbjct: 1874 YRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAF 1933
Query: 607 CPEP-PETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCP----EPPKT 661
CP P P+T + +R + P + P P + L P + L P + P
Sbjct: 1934 CPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQM--LLPMVDSQLPVV 1991
Query: 662 RVSSLPPEPPETGVS-HLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSL 714
SLPP PP L P P + L PP +R+ P P + +SL
Sbjct: 1992 NFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASL 2045
Score = 44.7 bits (104), Expect = 5e-04
Identities = 164/659 (24%), Positives = 216/659 (32%), Gaps = 159/659 (24%)
Query: 176 TEPGK-----YPCGEFSPRPPETRVSCLP-PEPPKTPVSSLRPEPPETGVSHLRP---QP 226
T PG+ +P + RPPE R LP P PP + + R + V H P Q
Sbjct: 1423 TGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQ----VIHSNPAGIQQ 1478
Query: 227 PKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGV----------SHLYLEPPG 276
Q+SS G H R +P Q P T S + E PG
Sbjct: 1479 ALAQLSSRQGSVTAPG-GHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPG 1537
Query: 277 TGV----------SHLCPEPPKTRVSHLHREPPETGVPDLCLE---PPKSRVSHLRPEPS 323
V + + P PPK R PP P+L E PP L +P
Sbjct: 1538 PMVRGVGGTPRDSAGVSPFPPKRR-----ERPPRK--PELLQEESLPPPHSSGFLGSKPE 1590
Query: 324 ---------ETGVSHLHPE--------------PPKTLVSSLHPEPP------------E 348
+TG L P P ++ + P P +
Sbjct: 1591 GPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSD 1650
Query: 349 TGV-----SHLCPEPPETRVSP------LRQLPPE--AGVSHL----CPEPPKTRVPPLR 391
+GV S + P R SP + PP+ G S L C PP + P
Sbjct: 1651 SGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP 1710
Query: 392 PETPKNGVSPLFPEP---PKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPP-ETGV 447
P P +G P P I RS+ G EP R SH RP PP + G
Sbjct: 1711 PPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGT-----EPGPIRPSH-RPGPPVQFGT 1764
Query: 448 SHLRPEPPKTRVSSLHLEPPET-GVSHLCP---------------EPPEK--DVSHLRPE 489
S + SL E T V+ P EP K D H PE
Sbjct: 1765 SDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPE 1824
Query: 490 PPDTGVSHLCPE-------PPKTRV------SHLRPEPS--ETGVSHLRPEPPKILVSSL 534
P +G L PE P +++ S L P G L P + L
Sbjct: 1825 PSSSG-QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPP 1883
Query: 535 HQAPPESSVSHLRPEPPETGVSHLR-PEPPKTRMYSLRPEPPDTGVS-HLCPEP-PKTRV 591
APP + +S L + S ++ E K + PP S CP P P T +
Sbjct: 1884 GPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSL 1943
Query: 592 SSLPPEPPETGVSHLCPEPPETRVSHLRPEPP--ETGVSHLRPEPPKTRMYSLRPEPPNT 649
+ + P + P P + L P + + + + P SL P PP
Sbjct: 1944 LQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPP-- 2001
Query: 650 GVSHLCPEPPKTRVSSLPP--EPPETGVSHLCPEPPETRV--SHLRPEPPETGVSRLHP 704
P PP + + P +PP V P P TRV S RP P G + LHP
Sbjct: 2002 ------PAPPPLSLLPVGPALQPPSLAVRP--PPAPATRVLPSPARPFPASLGRAELHP 2052
Score = 42.4 bits (98), Expect = 0.002
Identities = 101/416 (24%), Positives = 138/416 (33%), Gaps = 75/416 (18%)
Query: 199 PPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
PP PP P + P PE G P PP +S LE P G L P +V+ +
Sbjct: 826 PPVPPPPPYLASYPGFPENGA----PGPP---ISRFPLEEP--GPRPLPWPPGSDEVAKI 876
Query: 259 HLEPPE-----------TGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHR----------- 296
PP+ TG G G P PP+ R
Sbjct: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRG 936
Query: 297 -EPPETGVPD-----LCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETG 350
P E G P + PP ++V L P+P E G P+PPK P+P +
Sbjct: 937 IPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDE--TPKPPK-------PDPLKIT 987
Query: 351 VSHL---CPEPPETRVSPLRQLPPEAGVSHLCPEPPK--------TRVPPLRPETPKNGV 399
L PP +SP +L + + P + R R G
Sbjct: 988 KGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGR 1047
Query: 400 SPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRV 459
E R R + + G + PP RG E P+ + R
Sbjct: 1048 GARSREFRSYR--EFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRG 1105
Query: 460 SSLHLEPPETGVS---HLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPK-----TRVSHLR 511
S E E+ ++ P P E ++ + PP G P P + RV R
Sbjct: 1106 SETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPP-SPAPARFTARGGRVFTPR 1164
Query: 512 PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM 567
PS G RP PP++ +PP S L P+ P TG EP K ++
Sbjct: 1165 GVPSRRGRGGGRP-PPQVCPG---WSPPAKS---LAPKKPPTGPLPPSKEPLKEKL 1213
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 80.1 bits (196), Expect = 1e-14
Identities = 91/294 (30%), Positives = 110/294 (37%), Gaps = 57/294 (19%)
Query: 173 DEPTEPGKYPCGEFS-PRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQV 231
++P P P G RPP ++ LPP PP SL P PP G L P PP
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLP--ESLPPPPP--GGLPLPPMPPTGPA 270
Query: 232 SSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRV 291
S PP+ L P P + + PP +GV PP GV PP V
Sbjct: 271 PSGPPGPPQ-----LPPPAPGVHPPAPVVHPPASGV-----HPPAPGV-----HPPAPGV 315
Query: 292 SHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGV 351
PP GV PP S V P GV HP P + PP GV
Sbjct: 316 -----HPPAPGV-----HPPTSGV-----HPPAPGV---HPPAPGVHPPAPGVHPPAPGV 357
Query: 352 SHLCPEPPETRVSPLRQLPPEAGVSHLCP--EPPKTRVPPLRP--ETPKNGVSP----LF 403
PP V P PP AGV P P V P P P G+ P +
Sbjct: 358 -----HPPAPGVHP----PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVH 408
Query: 404 PEPPKTRIS--NLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPP 455
P+PP S + +PP + S+ + PP LRP P G ++ P PP
Sbjct: 409 PQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 67.4 bits (163), Expect = 7e-11
Identities = 88/270 (32%), Positives = 103/270 (38%), Gaps = 48/270 (17%)
Query: 524 PEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLC 583
P PP SL PP RP PP ++ L P PP SL P PP G L
Sbjct: 218 PAPP-----SLPAGPPGVK----RPPPPL--MNGLPPRPPLPE--SLPPPPP--GGLPLP 262
Query: 584 PEPPKTRVSSLPPEPPET-----GVSHLCP--EPPETRVSHLRP--EPPETGVSHLRP-- 632
P PP S PP PP+ GV P PP + V P PP GV P
Sbjct: 263 PMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGV 322
Query: 633 EPPKTRMYSLRP--EPPNTGVSHLCP--EPPKTRVSSLPP---EPPETGVSHLCP--EPP 683
PP + ++ P PP GV P PP V P PP GV P P
Sbjct: 323 HPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPA 382
Query: 684 ETRVSHLRP--EPPETGVSRLHPEPPKTRVSSLHAEPPESRVSH--LCPEPPETGVSHLR 739
V P PP G +HP+ P +H +PP S + P+PP S+
Sbjct: 383 APAVHPQAPGVHPPAPG---MHPQAP-----GVHPQPPGVHPSAPGVHPQPPGVHPSNPG 434
Query: 740 PEPPKPRVSSLRPEPLETRVSHLRPEPPET 769
PP P LRP PL + P PP T
Sbjct: 435 VHPPTPMPPMLRP-PLPSEGPGNIPPPPPT 463
Score = 63.9 bits (154), Expect = 7e-10
Identities = 71/240 (29%), Positives = 90/240 (37%), Gaps = 28/240 (11%)
Query: 523 RPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDT----- 577
RP PP L++ L PP + P PP G+ L P PP S P PP
Sbjct: 232 RPPPP--LMNGL---PPRPPLPESLPPPPPGGLP-LPPMPPTGPAPSGPPGPPQLPPPAP 285
Query: 578 GVSHLCP--EPPKTRVSSLPP--EPPETGVSHLCP--EPPETRVSHLRP--EPPETGVSH 629
GV P PP + V P PP GV P PP + V P PP GV
Sbjct: 286 GVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHP 345
Query: 630 LRP--EPPKTRMYSLRP---EPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEP-P 683
P PP ++ P PP+ GV P+ P ++ P GV P P
Sbjct: 346 PAPGVHPPAPGVHPPAPGVHPPPSAGVH---PQAPGVHPAAPAVHPQAPGVHPPAPGMHP 402
Query: 684 ETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPP 743
+ H +P +HP+PP S+ PP L P P G ++ P PP
Sbjct: 403 QAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 61.6 bits (148), Expect = 4e-09
Identities = 82/286 (28%), Positives = 97/286 (33%), Gaps = 49/286 (17%)
Query: 293 HLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVS 352
H E P P L PP + RP P ++ L P PP L SL P PP
Sbjct: 211 HFKMEKPPAP-PSLPAGPPGVK----RPPPPL--MNGLPPRPP--LPESLPPPPPGG--- 258
Query: 353 HLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFP--EPPKTR 410
P PP P PP G L P P P P +GV P P PP
Sbjct: 259 --LPLPPMPPTGPAPSGPP--GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPG 314
Query: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETG 470
+ PP GV P T G H PP GV P P + + PP G
Sbjct: 315 V-----HPPAPGVH------PPTSGVH----PPAPGV---HPPAPGVHPPAPGVHPPAPG 356
Query: 471 VSHLCP---EPPEKDVSHLRP---------EPPDTGVSHLCPEP-PKTRVSHLRPEPSET 517
V P PP V P P GV P P+ H +P
Sbjct: 357 VHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP 416
Query: 518 GVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPP 563
+ P+PP + S+ PP LRP P G ++ P PP
Sbjct: 417 SAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 78.6 bits (192), Expect = 3e-14
Identities = 173/725 (23%), Positives = 229/725 (31%), Gaps = 128/725 (17%)
Query: 175 PTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSL 234
P P P P+ T + PP P +P ++ P+ T + P P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK------- 1068
Query: 235 HLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHL 294
P T P PP S P + P T P PK ++
Sbjct: 1069 --GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT------PPSPKGGLA-- 1118
Query: 295 HREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHL 354
PP G P P PS G L PPK ++ PP
Sbjct: 1119 --TPPHKGAPTTPAATP----------PSPKG--GLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 355 CPEPPETRVSPLRQLP-PEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPE-------- 405
P P +P P P+ G++ P+ T P P +PK G++ P+
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 406 -PPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLH- 463
PP + L + PK + PP +G P P P PP SL
Sbjct: 1224 TPPSPK-GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA------PTPPAATPPSLKG 1276
Query: 464 --LEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSH 521
PP G + P PP + PP + S P P
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA---- 1332
Query: 522 LRPEPPKILVSSLHQAP------------PESSVSHLRPEPPETGVSH-----LRPEPPK 564
P PP + S P P + S P PP SH + P PK
Sbjct: 1333 --PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Query: 565 --TRMYSLRPEPPDTGVSHLCPE----PPKTRVSSLPPE-----PPETGVSHLCPEP--- 610
+ S + +P V L P+ P TR + P PP L P
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 611 -----PETRVSHLRPE-PPETGVSHLRPEPPKTRMYSLRP-EPPNTGVSHLCPEPPKTRV 663
P T S P P T S P PK S P + P T P P +
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV-I 1509
Query: 664 SSLPPEPPETGVSHLCPEPPETRV------SHLRPEPPETGVSRLHPEPPKTRVSSLHAE 717
S P E P T S P P + + L P+ + P P KT E
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
Query: 718 PPESRVSHLCPEPPETGVSHLRPEP-PK-----PRVSSLRPEPLETRVSHLRPEPPETGV 771
P + S PP S + P PK P V+S P+ T + + P PE G
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA-VTPPSPEKG- 1627
Query: 772 SHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPK----TGRVSSLCPE-----PTKTGAS 822
P P P+ PP T SSL+ P T ++ + P+ P K G +
Sbjct: 1628 ----PATPAPK--GTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 823 HLKEL 827
LKE+
Sbjct: 1680 ALKEV 1684
Score = 72.4 bits (176), Expect = 2e-12
Identities = 150/633 (23%), Positives = 208/633 (32%), Gaps = 102/633 (16%)
Query: 187 SPRPPETRVSCLPPEP---PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGV 243
SP+ T + PP P P TP P PP P PK P T
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA-----TPPSPKGG--------PATPS 981
Query: 244 SHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGV 303
P PP S P+ G P T P PP P T
Sbjct: 982 PKGAPTPPAATPPS-----PKGG--------PATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 304 PDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRV 363
P PP + + P+ T + P P + S P+ G P P +
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-----PKGG-----PATPSLKG 1078
Query: 364 SPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGV 423
+P PP A PP + P P +PK P PP + L + P K
Sbjct: 1079 AP---TPPAA-------TPPSPKGGPATP-SPKGAPMPPAATPPSPK-GGLATPPHKGAP 1126
Query: 424 SHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDV 483
+ PP +G P PP+ + PP + L PP+ + PP
Sbjct: 1127 TTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPK-GGLATPPPKGAPTTPAATPPSPKG 1184
Query: 484 SHLRPEP---PDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE 540
P P P T + P PK ++ P+ + T + P P L + + P
Sbjct: 1185 GLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 541 SSVSHLRPEP---PETGVSHLRPEPPKTRMYSLR---PEPPDTGVSH---LCPEPPKTRV 591
+ + P P P T P PP SL+ PP G + + P PK
Sbjct: 1243 TPAA-TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 592 SSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGV 651
++ PP+ T + P P + + PP G P PP P P T
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGT-----PPPKGA----PTPPAV----TPPSPKGT-- 1346
Query: 652 SHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSH-----LRPEPPETGVSRLHPEP 706
P P T SS P T S P PP SH + P P+ G + P+
Sbjct: 1347 ----PTLPATTPSS--KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG 1400
Query: 707 PKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPE- 765
T + + P ++ P P T P ++ P L+ + P+
Sbjct: 1401 DPTSPAVIPLSPKKA------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454
Query: 766 PPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS 798
P T S P LP S EPP ++V++
Sbjct: 1455 GPATPSSKGDPTLPAVTPPS-PKEPPAPKQVAT 1486
Score = 61.2 bits (147), Expect = 5e-09
Identities = 155/721 (21%), Positives = 223/721 (30%), Gaps = 98/721 (13%)
Query: 174 EPTEPGKYPCGEFSPRPPETRVSC---LPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQ 230
EPT P +P+ P T+V+ +P PP L+ P V + +T
Sbjct: 476 EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV 535
Query: 231 VSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTR 290
+SL P + L + T + + P + P +S P T
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS-----PEATL 590
Query: 291 VSHLHREPPETGVPDLCLEPP---KSRVSHLRPE----PSETG----VSHLHPEPPKTLV 339
EP G P + P S S ++ + P G S + P +
Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPL 650
Query: 340 SSLHP------------------EPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLC-- 379
S P P G L P+ + L LP S C
Sbjct: 651 ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV 710
Query: 380 -PEPPKTRVP----PLRPETPKNGVSPLFP---EPPKTR----ISNLRSEPPKIGVSHLC 427
P P T P L PE PK+ SP P PP T+ IS+ + P C
Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC 770
Query: 428 LEPPKTRGSHL-------------RPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHL 474
P + G+ P P VS PP + S+ P+T + +L
Sbjct: 771 --PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA----GPDTPIGNL 824
Query: 475 CPEPPEKDVSHLRPEPPDTGVSHL-CPEPPKTRVSHLRPEPSETGV-SHLRPEPPKILVS 532
+ S L P+ +S + P T S P P S + P PK +
Sbjct: 825 SSPVSPVEASFL----PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880
Query: 533 SLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPE-----PPDTGV-SHLCPEP 586
+ P S V+ P P E + + P M S P+ P G+ + P+
Sbjct: 881 PPKETPTPSVVN--LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 587 PKTRVSSLPPEP---PETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLR 643
T ++ PP P P T P PP P P+ G + P+ T +
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAA-----TPPSPKGGPATPSPKGAPTPPAATP 993
Query: 644 PEP---PNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVS 700
P P P T P PP S P T PP + P T +
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 701 RLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLR--PEPPKPRVSSLRPEPLETR 758
+ P P + S P + P PP + P P P+ + + P
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKG-APTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 759 VSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTK 818
PP G P L PPK + P G +++ P+
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 819 T 819
T
Sbjct: 1173 T 1173
Score = 57.0 bits (136), Expect = 9e-08
Identities = 129/554 (23%), Positives = 174/554 (31%), Gaps = 95/554 (17%)
Query: 306 LCLEPPKSRVSHLRPEPSET----GVSHLHPEPPKTLVS-SLHPE--PPET----GVSH- 353
L L P S + P P T L PE PK++ S SL P PP T G+SH
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 354 --LCPEPPETRVSPLRQLPPEAGVSHL--------CPEPPKTRVPPL--RPETPKNGVSP 401
L P + P A S P P V P RP T K P
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP 817
Query: 402 LFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSS 461
T I NL S + S L +GS P + P PP + +
Sbjct: 818 ------DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS------PTPPSPKGA- 864
Query: 462 LHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSET-GVS 520
P + V+ L P K V+ E P V +L P + P P + +S
Sbjct: 865 ----PTPSAVTPLSP----KGVTLPPKETPTPSVVNL----PFPKEGPATPAPKQAPALS 912
Query: 521 HLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVS 580
P K + + P S P PP PP + P P
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAA-------TPPSPKGGPATPSPK----- 960
Query: 581 HLCPEPPKTRVSSLPPEP---PETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKT 637
P PP ++ PP P P T P PP P P+ G + P+ T
Sbjct: 961 -WAPTPP----AATPPSPKGGPATPSPKGAPTPPAAT-----PPSPKGGPATPSPKGAPT 1010
Query: 638 RMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP--- 694
P P + + P+ T ++ PP P + + P+ T + P P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 695 PETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRP-- 752
P T + P PP A PP + P P + PP P+ P
Sbjct: 1071 PATPSLKGAPTPPA-------ATPPSPKGGPATPSPKGAPMPP-AATPPSPKGGLATPPH 1122
Query: 753 --EPLETRVSHLRPE-----PPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPK 805
P + P+ PP G P L PPK + P
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 806 TGRVSSLCPEPTKT 819
G +++ P+ T
Sbjct: 1183 KGGLATPSPKGAPT 1196
Score = 39.3 bits (90), Expect = 0.019
Identities = 150/673 (22%), Positives = 229/673 (34%), Gaps = 100/673 (14%)
Query: 175 PTEPGKYPCGEFSPRPP----ETRVSCLPPEPP-KTPVSSLRPEPPETGVSHLRPQPPKT 229
P+E P G +P PP C+ P ++ V+SL P T ++ PQ T
Sbjct: 192 PSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDT 249
Query: 230 QVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKT 289
+SS+ + P G L+ SL + S P T P+ P +
Sbjct: 250 TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP-----PDFPIS 304
Query: 290 RVSH---LHREP-------PETGVPDLCLEPPKSRVSHLRPEPSETGVSH------LHPE 333
SH LH+ +TG P +P +S + S TG S+ + P
Sbjct: 305 LGSHLAPLHQSSFGSVQLLGQTG-PSALSDPTVKTIS---VDHSSTGASYPSQRSVIPPL 360
Query: 334 PPKT-----------LVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEP 382
P + +V+ + P T S C V+ L P + L P
Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLI-LKSSP 419
Query: 383 PKTRVPPLRPETPKN--GVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRG--SHL 438
T PL + P + G +PL P T + + P C+ PP + G S++
Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCT----IAAAPTTTFEVATCVSPPMSSGPISNI 475
Query: 439 RPEPPETGV-SHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSH 497
P P V + + P+ P T+V++ P PP D L+ P V
Sbjct: 476 EPTSPAALVMAPVAPKEPSTQVATTLRIP---------VSPPLPDPEDLKNLPSSVLVKF 526
Query: 498 LCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSH 557
+ +T + L P + L + ++ + AP S PE +S
Sbjct: 527 PTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS- 585
Query: 558 LRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGV---SHLCPEP--PE 612
P T EP G +P + S L + + S+ P+ P
Sbjct: 586 ----PEATLAKKSLGEPLPIG------KPASSMTSPLGVNSSASVIKTDSYAGPDSAGPL 635
Query: 613 TRVSHLRPE----PPETG-VSHLRPEPPK-TRMYSLRPEPPNTGVSHLCPEPPKTRVSSL 666
+ S + P P E+ + + P K T Y+ P G L P+ + +L
Sbjct: 636 LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTL 695
Query: 667 PPEPPETGVSHLCPEPPETR-------VSHLRPEPPETGVSRLHP---EPPKTR----VS 712
P S CP P + L PE P++ S P PP T+ +S
Sbjct: 696 TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755
Query: 713 SLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVS 772
A P + CP ++G S + P PL VS PP T
Sbjct: 756 HTSALAPVASSPKECP-TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP-TKKG 813
Query: 773 HLHPELPKPRVSS 785
P+ P +SS
Sbjct: 814 SAGPDTPIGNLSS 826
Score = 37.7 bits (86), Expect = 0.056
Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 29/171 (16%)
Query: 526 PPKILVSSLHQAPPESSV-----SHLRPEPPETGV----SHLRPEPPKTRMYSLRPEPPD 576
PP +L S A ES + + P P+T + S + P P T P PP
Sbjct: 154 PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGT------PSPPC 207
Query: 577 --TGVSHLCPEPP---KTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLR 631
+ V + C P ++ V+SLP P T ++ P+ +T +S + P G L+
Sbjct: 208 IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLK 267
Query: 632 --PEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
PP S + P T KT + PP+ P + SHL P
Sbjct: 268 GPVSPPAALSLSTQSLPVVT-------SSQKTAGPNTPPDFPISLGSHLAP 311
Score = 33.9 bits (76), Expect = 0.82
Identities = 87/367 (23%), Positives = 132/367 (35%), Gaps = 60/367 (16%)
Query: 78 LPKISLRGPQ---ADPKSRKKKLLKKAALFSKLSPAQPARKAFV----------EEVEAQ 124
LP + P+ A P SR+ + A L SK +PA A K + ++ A
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 125 LMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKL---EDAGSCEGQEKTTDEPTEPGKY 181
K A + PP + K ++L S +E T P
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 182 PCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPET 241
G +P P T P PP TP SSL+ P T + + + T + P +
Sbjct: 1625 EKGPATPAPKGT-----PTSPPVTP-SSLKDSP--TSPASVTCKMGATVPQASKGLPAKK 1676
Query: 242 GVSHLR-----PEPPKTQ-VSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLH 295
G + L+ P P T +++ + P+T S P +CP+P S
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP-------ICPDPSAKNGS--- 1726
Query: 296 REPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHP-EPPKTLVSS---------LHPE 345
+ P T P L P + S + + S P PP++ S+ + P+
Sbjct: 1727 KGPLSTVAPAPLL--PVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 346 PPETGVSHLCPEPPET---RVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETP--KNGVS 400
P VS P PP + SP+ LPP+ L P P +P P ++ +
Sbjct: 1785 PESASVS-AAPSPPVSLPLAPSPVPTLPPKQ--QFLPSSPGLVLESPSKPLAPADEDELL 1841
Query: 401 PLFPEPP 407
PL P P
Sbjct: 1842 PLIPPEP 1848
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 77.8 bits (190), Expect = 5e-14
Identities = 87/335 (25%), Positives = 129/335 (38%), Gaps = 53/335 (15%)
Query: 405 EPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPP------KTR 458
EPP T+ + EPP + + EPP+T P+P E + P+PP +T
Sbjct: 88 EPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG--PQPAEGPQTAEGPQPPERKRRRRTA 145
Query: 459 VSSLHLEPPETGVSHL-CPEPPEKDVSHLRPEPPDTGV-----SHLCPEPPKTRVSHLRP 512
+ L+ E P+ ++ R + V + RV LR
Sbjct: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLR- 204
Query: 513 EPSETGVSHLRPEPPKILVSSLHQAPP--ESSVSHLRPEPPETGVSHLRPEPPKTRMYSL 570
T + L L + + AP + HL P+ P V + P PP+
Sbjct: 205 ---NTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPR------ 255
Query: 571 RPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHL 630
PP + P PP+ ++ +PP P S + P PP R++ + P PP V
Sbjct: 256 ---PP------MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306
Query: 631 RPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHL 690
P P + P PP ++ + P PP RV PP PP + P PP ++ L
Sbjct: 307 PPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV---PPGPP------MAPLPPGPPMAPL 357
Query: 691 RPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSH 725
P PP ++ L P PP + PP S V H
Sbjct: 358 PPGPP---MAPLPPGPPMAPL------PPRSHVPH 383
Score = 71.2 bits (173), Expect = 5e-12
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 27/181 (14%)
Query: 602 GVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKT 661
G + P HL P+ P V + P PP+ M + P PP + + P PP +
Sbjct: 221 GAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGS 280
Query: 662 RVSSLP------PEPPETGVSHLCPEPPETRV---SHLRPEPPETGVSRLHPEPPKTRVS 712
R++ +P P PP ++ + P PP V + P PP ++R+ P PP RV
Sbjct: 281 RMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV- 339
Query: 713 SLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVS 772
PP ++ L P PP + P PP P ++ L P P + P PP + V
Sbjct: 340 -----PPGPPMAPLPPGPP------MAPLPPGPPMAPLPPGP------PMAPLPPRSHVP 382
Query: 773 H 773
H
Sbjct: 383 H 383
Score = 66.6 bits (161), Expect = 1e-10
Identities = 53/190 (27%), Positives = 79/190 (41%), Gaps = 25/190 (13%)
Query: 353 HLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRIS 412
HL P+ P V P+ +PP + P PP+ + P+ P P S + P PP R++
Sbjct: 236 HLVPQLPRPPVLPVPPMPPRPP---MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
Query: 413 NLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVS 472
+ PP V P G + P PP ++ + P PP RV PP ++
Sbjct: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV------PPGPPMA 346
Query: 473 HLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKI--- 529
L P PP + P PP ++ L P PP + P P + V H P I
Sbjct: 347 PLPPGPP------MAPLPPGPPMAPLPPGPP------MAPLPPRSHVPHTGLAPVHITWA 394
Query: 530 -LVSSLHQAP 538
+++S + P
Sbjct: 395 PVINSYYACP 404
Score = 62.0 bits (149), Expect = 3e-09
Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 9/157 (5%)
Query: 281 HLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVS 340
HL P+ P+ V + PP P + PP+ ++ + P S + P PP ++
Sbjct: 236 HLVPQLPRPPVLPVPPMPPR---PPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
Query: 341 SLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVS 400
+ P PP V P P P+ +PP ++ + P PP RVPP P P
Sbjct: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGP 352
Query: 401 PLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSH 437
P+ P PP ++ L PP + PP++ H
Sbjct: 353 PMAPLPPGPPMAPLPPGPPMAPL------PPRSHVPH 383
Score = 61.2 bits (147), Expect = 5e-09
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 653 HLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVS 712
HL P+ P+ V +PP PP + + P PP + + P PP SR+ P PP R++
Sbjct: 236 HLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPG---SRMAPVPPGPRMA 292
Query: 713 SLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVS 772
+ PP + V P P + P PP P ++ + P P RV P P
Sbjct: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGP 352
Query: 773 HLHPELPKPRVSSLHLEPP 791
+ P P P ++ L PP
Sbjct: 353 PMAPLPPGPPMAPLPPGPP 371
Score = 60.8 bits (146), Expect = 6e-09
Identities = 43/156 (27%), Positives = 68/156 (43%), Gaps = 18/156 (11%)
Query: 629 HLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVS 688
HL P+ P+ + + P PP + P PP+ ++ +PP P S + P PP R++
Sbjct: 236 HLVPQLPRPPVLPVPPMPPRPP---MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
Query: 689 HLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRV- 747
+ P PP + P PP ++ + PP + P PP ++ + P PP RV
Sbjct: 293 PVPPWPP------MAPVPPWPPMAPVPTGPP------MAPVPPGPPMARVPPGPPMARVP 340
Query: 748 --SSLRPEPLETRVSHLRPEPPETGVSHLHPELPKP 781
+ P P ++ L P PP + P P P
Sbjct: 341 PGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLP 376
Score = 59.3 bits (142), Expect = 2e-08
Identities = 49/184 (26%), Positives = 77/184 (41%), Gaps = 21/184 (11%)
Query: 183 CGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETG 242
C P+ P V +PP PP+ P+ + P PP + + P PP ++++ + PP
Sbjct: 234 CVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV---PPGPR 290
Query: 243 VSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETG 302
++ + P PP V P + PPG ++ + P PP RV PP
Sbjct: 291 MAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV------PPG-- 342
Query: 303 VPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETR 362
P + PP ++ L P P ++ L P PP + P PP + V H P
Sbjct: 343 -PPMAPLPPGPPMAPLPPGPP---MAPLPPGPP------MAPLPPRSHVPHTGLAPVHIT 392
Query: 363 VSPL 366
+P+
Sbjct: 393 WAPV 396
Score = 59.3 bits (142), Expect = 2e-08
Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 15/162 (9%)
Query: 269 HLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGV- 327
HL + P V + P PP+ + + PP +P + PP SR++ + P P V
Sbjct: 236 HLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVP 295
Query: 328 -----SHLHPEPPKTLVSS---LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLC 379
+ + P PP V + + P PP ++ + P PP RV PP ++ L
Sbjct: 296 PWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV------PPGPPMAPLP 349
Query: 380 PEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKI 421
P PP +PP P P P+ P PP++ + + P I
Sbjct: 350 PGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHI 391
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 28/182 (15%)
Query: 221 HLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVS 280
HL PQ P+ V + PP + P PP+ ++ + PP V PPG S
Sbjct: 236 HLVPQLPRPPVLPVPPMPPRPPMV---PMPPRPPIAPM---PPMAPV------PPG---S 280
Query: 281 HLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVS 340
+ P PP R++ + PP VP PP + P P+ ++ + P PP ++
Sbjct: 281 RMAPVPPGPRMAPVPPWPPMAPVPPW---PP------MAPVPTGPPMAPVPPGPP---MA 328
Query: 341 SLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVS 400
+ P PP V P P P+ LPP ++ L P PP +PP R P G++
Sbjct: 329 RVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP-RSHVPHTGLA 387
Query: 401 PL 402
P+
Sbjct: 388 PV 389
Score = 53.5 bits (127), Expect = 1e-06
Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 29/167 (17%)
Query: 440 PEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLC 499
P PP + P PP+ ++ + P S + P PP ++ + P PP ++ +
Sbjct: 248 PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPP---MAPVP 304
Query: 500 PEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLR 559
P PP + P P+ ++ + P PP + + PP ++ + P PP +
Sbjct: 305 PWPP------MAPVPTGPPMAPVPPGPP------MARVPPGPPMARVPPGPP------MA 346
Query: 560 PEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP--PETGVS 604
P PP M L P PP + P PP ++ LPP P TG++
Sbjct: 347 PLPPGPPMAPLPPGPP------MAPLPPGPPMAPLPPRSHVPHTGLA 387
Score = 53.5 bits (127), Expect = 1e-06
Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 16/157 (10%)
Query: 175 PTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSL 234
P P + P PRPP ++ +PP P P S + P PP ++ + P PP V
Sbjct: 250 PPMPPRPPMVPMPPRPP---IAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306
Query: 235 HLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHL 294
P + P PP ++ + PP V PPG ++ L P PP +
Sbjct: 307 PPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV------PPGPPMAPLPPGPPMAPLPPG 360
Query: 295 HREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH 331
P P + PP+S V H TG++ +H
Sbjct: 361 PPMAPLPPGPPMAPLPPRSHVPH-------TGLAPVH 390
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 3/121 (2%)
Query: 674 GVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPET 733
G + P HL P+ P V + P PP+ + + PP + + + P PP
Sbjct: 221 GAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPG- 279
Query: 734 GVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKT 793
S + P PP PR++ + P P V P P + P P P ++ + PP
Sbjct: 280 --SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMA 337
Query: 794 R 794
R
Sbjct: 338 R 338
Score = 33.1 bits (74), Expect = 1.4
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 681 EPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPE 732
EPP T+ + EPP + + EPP+T V +P E + P+PPE
Sbjct: 88 EPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG--PQPAEGPQTAEGPQPPE 137
Score = 31.2 bits (69), Expect = 5.3
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 309 EPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETR 362
EPP ++ + EP + EPP+T V P+P E + P+PPE +
Sbjct: 88 EPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG--PQPAEGPQTAEGPQPPERK 139
Score = 30.4 bits (67), Expect = 9.0
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 166 EGQEKTTDEPTEPGK-YPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRP 224
EG + D+ E G + + PP T+ EPP + + EPP+T V P
Sbjct: 64 EGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVE--GP 121
Query: 225 QPPKTQVSSLHLEPPE 240
QP + ++ +PPE
Sbjct: 122 QPAEGPQTAEGPQPPE 137
Score = 30.4 bits (67), Expect = 9.0
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 285 EPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPK 336
EPP T+ EPP + EPP++ V P+P+E + P+PP+
Sbjct: 88 EPPLTKPEQQQEEPPLLELKQEQEEPPQTTVE--GPQPAEGPQTAEGPQPPE 137
Score = 30.4 bits (67), Expect = 9.0
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 717 EPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPE 768
EPP ++ EPP + + EPP+ V P+P E + P+PPE
Sbjct: 88 EPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG--PQPAEGPQTAEGPQPPE 137
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 77.4 bits (189), Expect = 6e-14
Identities = 116/501 (23%), Positives = 180/501 (35%), Gaps = 76/501 (15%)
Query: 343 HPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPL 402
HP + H + + +P+ Q PP P PP+ + P P P
Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP------- 782
Query: 403 FPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPET-GVSHL-RPE-PPKTRV 459
P P+ ++S PP + + + P+ GS P T + HL +PE PP
Sbjct: 783 -PSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQ 841
Query: 460 SSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGV 519
H PP + P + +P P + L P+P R + P ++T +
Sbjct: 842 PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKP--ARPPAVSPALTQTPL 899
Query: 520 SHLRP--EPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDT 577
P +PP++L+ + PP ++ ++ + + ++P P ++ +PP
Sbjct: 900 LPQPPMAQPPQVLLED--EEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Query: 578 GVSHLCPEPPKTRVSSL------PPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLR 631
P PP V PP PP+ P+PP + P P HL+
Sbjct: 958 -----LPPPPHPSVQQQLQQQPPPPPPPQ-------PQPPPQQQHQPPPRP-----VHLQ 1000
Query: 632 PEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLR 691
P T ++ PP G P P + P +P + H P H +
Sbjct: 1001 PMQFSTH---IQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPR-------HHK 1050
Query: 692 PEPPETGVSRLHP------EPPKTRVSSL-HAEPPESRVSHLCPEPPE-TGVSHLRPEP- 742
+P TG R P P ++ SL H PP+ V P+ E S ++P+P
Sbjct: 1051 SDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ---PKKQELRAASVVQPQPL 1107
Query: 743 -----PKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVS 797
K +R EP LRPEPP+ HPE K V K V
Sbjct: 1108 VVVKEEKIHSPIIRSEPFS---PSLRPEPPK------HPESIKAPVHLPQRPEMKPVDVG 1158
Query: 798 SLRLEPPKTGRVSSLCPEPTK 818
+ PP+ P+ K
Sbjct: 1159 RPVIRPPEQNAPPPGAPDKDK 1179
Score = 76.6 bits (187), Expect = 1e-13
Identities = 124/515 (24%), Positives = 177/515 (34%), Gaps = 120/515 (23%)
Query: 168 QEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKT----PVSSLRPEPP---ETGVS 220
Q+ P +P P P PP+ + PP PP + +++ PP T V
Sbjct: 747 QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP 806
Query: 221 HLRPQPPKTQVSS--------LHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYL 272
L PQ P + LHL PE HL P+PP+ H PP H +
Sbjct: 807 VLEPQLPGSVFDPIGHFTQPILHLPQPEL-PPHL-PQPPE------HSTPPHLN-QHAVV 857
Query: 273 EPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHP 332
PP + + P+ P P +R + L P+P+
Sbjct: 858 SPP--ALHNALPQQPSR---------------------PSNRAAALPPKPARPPA----- 889
Query: 333 EPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRP 392
P + L P+PP + E E PL + + + L P T PL P
Sbjct: 890 VSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT---PLLP 946
Query: 393 ETP-KNGVSPLFPEPPKTRI-SNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHL 450
++ P P PP + L+ +PP PP +P+PP
Sbjct: 947 SVKVQSQPPPPLPPPPHPSVQQQLQQQPPP--------PPPP------QPQPPPQQQHQP 992
Query: 451 RPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTR---- 506
P P +HL+P + P PP+ +P P G P+P K +
Sbjct: 993 PPRP-------VHLQPMQFSTHIQQPPPPQGQ----QPPHPPPGQQPPPPQPAKPQQVIQ 1041
Query: 507 ----VSHLRPEPSETGVSHLRPEPPKILVSS---------LHQAPPESSVSHLRPEPPET 553
H + +P TG HLR P +++ S HQ+PP+ +V + E
Sbjct: 1042 HHHSPRHHKSDPYSTG--HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099
Query: 554 GVSHLRP----EPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVS-----SLP--PEPPETG 602
V +P + K +R EP L PEPPK S LP PE
Sbjct: 1100 SVVQPQPLVVVKEEKIHSPIIRSEPFSPS---LRPEPPKHPESIKAPVHLPQRPEMKPVD 1156
Query: 603 VSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKT 637
V PPE PP + + PKT
Sbjct: 1157 VGRPVIRPPEQNA-----PPPGAPDKDKQKQEPKT 1186
Score = 64.7 bits (156), Expect = 4e-10
Identities = 118/493 (23%), Positives = 170/493 (34%), Gaps = 96/493 (19%)
Query: 284 PEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSL- 342
P PP + PP +P KS P T V L P+ P ++ +
Sbjct: 766 PPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP----PPFIATQVPVLEPQLPGSVFDPIG 821
Query: 343 HPEPPETGVSHLC-PE-PPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVS 400
H P + HL PE PP P PP + P P +P P N +
Sbjct: 822 HFTQP---ILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAA 878
Query: 401 PLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHL---RPEPPKT 457
L P+P + PP + P + L P+PP + EPP
Sbjct: 879 ALPPKP---------ARPPAVS--------PALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
Query: 458 RVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSET 517
++S+ ++ + + P P ++ +PP L P P + L+ +P
Sbjct: 922 PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP----LPPPPHPSVQQQLQQQPPPP 977
Query: 518 GVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDT 577
+P+PP HQ PP HL+P T + +P PP+ + +P P
Sbjct: 978 PPP--QPQPPP---QQQHQPPPRP--VHLQPMQFSTHIQ--QPPPPQGQ----QPPHPPP 1024
Query: 578 GVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKT 637
G P PP+ P +P + H P H + +P TG HLR P
Sbjct: 1025 GQQ---PPPPQ------PAKPQQVIQHHHSPR-------HHKSDPYSTG--HLREAPSPL 1066
Query: 638 RMYS---------LRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVS 688
++S PP V P+ + R +S+ P V P R
Sbjct: 1067 MIHSPQMSQFQSLTHQSPPQQNVQ---PKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE 1123
Query: 689 ----HLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESR---VSHLCPEPPETGVSHLRPE 741
LRPEPP+ HPE K V + PE + V PPE P
Sbjct: 1124 PFSPSLRPEPPK------HPESIKAPVHL--PQRPEMKPVDVGRPVIRPPEQNA----PP 1171
Query: 742 PPKPRVSSLRPEP 754
P P + EP
Sbjct: 1172 PGAPDKDKQKQEP 1184
Score = 63.5 bits (153), Expect = 1e-09
Identities = 84/338 (24%), Positives = 118/338 (34%), Gaps = 54/338 (15%)
Query: 188 PRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHL---EPPETGVS 244
P P R + LPP+P + P S P + L PQPP Q + L EPP ++
Sbjct: 870 PSRPSNRAAALPPKPARPPAVS-----PALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT 924
Query: 245 HLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVP 304
++ + Q+ + P + +PP L P P + L ++PP P
Sbjct: 925 SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP----PPLPPPPHPSVQQQLQQQPPPPPPP 980
Query: 305 DLCLEP-----PKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPP 359
P P R HL+P T H+ PP HP P + P PP
Sbjct: 981 QPQPPPQQQHQPPPRPVHLQPMQFST---HIQQPPPPQGQQPPHPPPGQQ------PPPP 1031
Query: 360 ET---------RVSPLRQLPPEAGVSHL--CPEPPKTRVPPLRPETPKNGVSP----LFP 404
+ SP HL P P P + SP + P
Sbjct: 1032 QPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091
Query: 405 EPPKTRISNLRSEPPKIGVSHLCLEPPKTRGS----HLRPEPPETGVS-----HL--RPE 453
+ + R +++ P + V + P R LRPEPP+ S HL RPE
Sbjct: 1092 KKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPE 1151
Query: 454 PPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPP 491
V + PPE P P+KD P+ P
Sbjct: 1152 MKPVDVGRPVIRPPEQNAPP--PGAPDKDKQKQEPKTP 1187
Score = 57.8 bits (138), Expect = 5e-08
Identities = 92/365 (25%), Positives = 126/365 (34%), Gaps = 69/365 (18%)
Query: 109 PAQPARKAFVEEVEAQ--LMTKHPLAMYPN-LGED----MPPDLLLQVLKPLDPERKLED 161
P +PAR V Q L+ + P+A P L ED PP +Q+ L +K++
Sbjct: 881 PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP 940
Query: 162 AGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSC-LPPEPPKTPVSSLRPEPPETGVS 220
K +P P P PP V L +PP P +P P +
Sbjct: 941 PTPLLPSVKVQSQPPPP--------LPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ---- 988
Query: 221 HLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVS 280
+ QPP V HL+P + +P PP+ Q +PP PPG
Sbjct: 989 --QHQPPPRPV---HLQPMQFSTHIQQPPPPQGQ------QPPH--------PPPGQQPP 1029
Query: 281 HLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVS 340
P P+ + H H P HLR PS +H S
Sbjct: 1030 PPQPAKPQQVIQHHHSPRHHKSDP--------YSTGHLREAPSPL---MIHSPQMSQFQS 1078
Query: 341 SLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTR----VPPLRPETPK 396
H PP+ V P+ E R + + Q P V P R P LRPE PK
Sbjct: 1079 LTHQSPPQQNVQ---PKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPK 1135
Query: 397 NGVSPLFPEPPKTRIS-NLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPP 455
+ PE K + R E + V + PP+ PP + + P
Sbjct: 1136 H------PESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNA-----PPPGAPDKDKQKQEP 1184
Query: 456 KTRVS 460
KT V+
Sbjct: 1185 KTPVA 1189
Score = 36.6 bits (83), Expect = 0.13
Identities = 45/167 (26%), Positives = 63/167 (37%), Gaps = 29/167 (17%)
Query: 334 PPKTLVSSLHPEPPETGVSHLCPE--PPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLR 391
PP+T +P PP H P P +P+ + P + P PP+ + PP
Sbjct: 205 PPQTQTPQPNP-PPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
Query: 392 PETPKNGVSPLF---PEPPKTRISNLR----SEPPKIGVSHLCLEPPKTRGSHLRPEPPE 444
P P+ P+P KT+ R + P I H EPP L PEP
Sbjct: 264 APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH---EPPS-----LPPEPKT 315
Query: 445 TGVSHLRPEPPKTRVSSLHLEPPETGV----SHLCPEPPEKDVSHLR 487
T + + R SS ++PP+ V H PE K L+
Sbjct: 316 TKLG-------QRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLK 355
Score = 33.1 bits (74), Expect = 1.4
Identities = 136/696 (19%), Positives = 231/696 (33%), Gaps = 106/696 (15%)
Query: 188 PRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQ--------------VSS 233
P+P +T +PP+P P + +P + PQP KT+ +
Sbjct: 244 PQPLQTPPP-VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 234 LHLEPPETGVSHLRPEPPKTQV-----SSLHLEPPETGVSHLYLEPPGTGVSHL------ 282
+H EPP L PEP T++ SS ++PP+ V P S +
Sbjct: 303 IH-EPPS-----LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKC 356
Query: 283 CPEPPKTRVSHLHR----------EPPETGVPDLC---LEPPKSRVSHLRPEPSETGVSH 329
C K + H + G+ D C P + E E +
Sbjct: 357 CSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQ 416
Query: 330 LHPEPPKTLVSSLHP-EPPETGVSHLCPEPPETRVSPLRQLPPE------AGVSHLCPEP 382
+ + S+ + PP+ V + + + ++P E A S P P
Sbjct: 417 EFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP 476
Query: 383 PKTRVPPLRPETPKNGVSPL------FPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGS 436
K PP ++ + S E R++ L+ + + L P+
Sbjct: 477 TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN-- 534
Query: 437 HLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVS 496
+P+ E + E K + E E EPP K + ++ VS
Sbjct: 535 --KPKKKEKDKKEKKKEKHKRK------EEVEENKKSKAKEPPPKKTK--KNNSSNSNVS 584
Query: 497 HLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE--SSVSHLRPEPPETG 554
P P K++ E + E + L +++ P E V H+ + E
Sbjct: 585 KKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHI-IQSREPS 643
Query: 555 VSHLRPEPPKTRMYSLRP------EPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 608
+ + P+ + +L+P E T +P +V + G S
Sbjct: 644 LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
Query: 609 EPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPP 668
E S E + + P+ K + + R + + H + V PP
Sbjct: 704 ESS----SESSSSDSEDSETEMAPK-SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP 758
Query: 669 EPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCP 728
PP+ P PP +P PP P P+ ++ + PP + +
Sbjct: 759 PPPQQ------PPPPPPPQQQQQPPPPPP-----PPSMPQQAAPAMKSSPPPFIATQVPV 807
Query: 729 EPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGV-SHL--HPELPKPRVSS 785
P+ S P + P+P HL P+PPE HL H + P + +
Sbjct: 808 LEPQLPGSVFDPIGHFTQPILHLPQP--ELPPHL-PQPPEHSTPPHLNQHAVVSPPALHN 864
Query: 786 LHLEPPK--TRRVSSLRLEPPKTGRVSSLCPEPTKT 819
+ P + R ++L PPK R ++ P T+T
Sbjct: 865 ALPQQPSRPSNRAAAL---PPKPARPPAVSPALTQT 897
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 77.0 bits (188), Expect = 8e-14
Identities = 177/721 (24%), Positives = 247/721 (34%), Gaps = 109/721 (15%)
Query: 147 LQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTP 206
L V +P +R + S GQ +P +P P T VS LP P T
Sbjct: 1226 LAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQA--VAPTPGPTPVSVLPSSTPST- 1282
Query: 207 VSSLRPEPPETGVSHLRPQPPKTQVSSLHL------EPPETGVSHLRPEPPKTQVSSLHL 260
P P + Q P T V++ + + P G++ + P P + S L
Sbjct: 1283 ----TPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGL 1338
Query: 261 EP---PETGVSHLYLEPPGTGVSHLCPEPPKTRVSHL----HREPPET-----GVPDLCL 308
P ++ L P G + P P T V L H PE G L +
Sbjct: 1339 PAVLNPRPTLTPGRLPTPTLGTAR-APMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTI 1397
Query: 309 EPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQ 368
P S L P P+ + + + P + VSS P + + P S
Sbjct: 1398 SSPLHVPSSL-PGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLT 1456
Query: 369 LPPEA--GVSHLCPEPPKTRVPPLRPETP----KNGVSPLFPEPPKTRISNLRSEPPKIG 422
+P A VS P + PPL P P ++P P + ++ + P +
Sbjct: 1457 IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLS 1516
Query: 423 VSH-----LCLEPPKTR----GSHLRPE-----PPETGVSHLRPEPPKTRVSSLHLEPPE 468
S L L P + S + P P + ++ P P + L P
Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPA 1576
Query: 469 TGVSHLCPEPPEKDVSHLRP-EPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPP 527
+ S P L P P T + P PP + L P P V P
Sbjct: 1577 SSASQALATP-------LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPV 1629
Query: 528 KILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRM----YSLRPEPPDTGVSHLC 583
++ S + P +S++ P P T V L P +T + S P P T L
Sbjct: 1630 PVMAPS---STPGTSLASASPVPAPTPV--LAPSSTQTMLPAPVPSPLPSPASTQTLALA 1684
Query: 584 PEPPKTRVSSLPPEPPETGVSHLCPEPP-------ETRVSHLRPEPPETGVSHLRPEPP- 635
P T S P + G + P+ P T S L P P +T L P PP
Sbjct: 1685 PALAPTLGGSSPSQTLSLGTGN--PQGPFPTQTLSLTPASSLVPTPAQT--LSLAPGPPL 1740
Query: 636 -KTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
T+ SL P PP S + P P T L P + S L P +T L P P
Sbjct: 1741 GPTQTLSLAPAPPLAPASPVGPAPAHT----LTLAPASSSASLLAPASVQTLT--LSPAP 1794
Query: 695 PETGVSRLHPEPPKT-RVSSLHAEPPESRVSHLCPEP------PETGVSHLRPEPPKPRV 747
V L P +T ++ + P S+ S L P T VS L +P
Sbjct: 1795 ----VPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDT 1850
Query: 748 SSLRPEPLETRVSHLRPEPPETGVSHLHP----ELPKPRVSSLHLE--PPKTRRVSSLRL 801
+LR P P PP T S P + P P S +L+ K +R S RL
Sbjct: 1851 LTLRSGP---------PSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERL 1901
Query: 802 E 802
E
Sbjct: 1902 E 1902
Score = 42.0 bits (97), Expect = 0.003
Identities = 153/646 (23%), Positives = 199/646 (30%), Gaps = 131/646 (20%)
Query: 170 KTTDEPTEPGKYPCGEFSPRP-PETR---------VSCLPPEPPKTPVSSLRPEPPETGV 219
+T T P P E PRP P R + L P P PV P P
Sbjct: 2419 QTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILP 2478
Query: 220 SHLRPQPPKTQ----VSSLHLEPPETGVSHLRPEPPKTQV------SSLHLEPPETGVSH 269
H+ P PP SS PP PP Q S L L PP +S
Sbjct: 2479 VHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISA 2538
Query: 270 LYLEPPGTGV---SHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVS---HLRPEPS 323
P G+ + LC + + S + L L PPK + + P S
Sbjct: 2539 SVTNLP-LGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILP-VS 2596
Query: 324 ETGVSHLHPEPPKTLVSSLHP-----EPPETGVSHLCPEPPETRVSPL-------RQLPP 371
E +S P TL + P E P++ PE PL +LPP
Sbjct: 2597 EKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPP 2656
Query: 372 EAGVSHLCPEP----------PKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKI 421
A EP + + P PE P+ V+ P + + E P
Sbjct: 2657 SAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSP 2716
Query: 422 GVSHLCLEPPKTRGSHLRPEPPETGVSHLRP-EPPKTRVSSLHLEPPETGVSHLCPEPPE 480
PP+ R S + G RP +PP +V L P L E
Sbjct: 2717 A------RPPRRRTS---ADVEIRGQGTGRPGQPPGPKV--LRKLP-----GRLVTVVEE 2760
Query: 481 KDVSHLRPEP--------PDTGVSHLCPEPPKTRVSHLRPE-------PSETGVSHLRPE 525
K++ R + P + P P R S PE P E S P
Sbjct: 2761 KELVRRRRQQRGAASTLVPGVSETSASPGSPSVR-SMSGPESSPPIGGPCEAAPSSSLPT 2819
Query: 526 PP-KILVSSLH--------QAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPD 576
PP + ++ H +P + L PP V R PPK + P
Sbjct: 2820 PPQQPFIARRHIELGVTGGGSPENGDGALLAITPP--AVKRRRGRPPKK---NRSPADAG 2874
Query: 577 TGVSHLCPEPPKTRVSSLPPEP-PET--------------GVSHLCPEPPETRVSHLRPE 621
GV K + + P P PET G L P+P RP
Sbjct: 2875 RGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVH------RPN 2928
Query: 622 PPETGV-SHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 680
P + V R PPK R + P G + + PP P S L P
Sbjct: 2929 PLLSPVEKRRRGRPPKAR------DLPIPGTISSAGDGNSESRTQPPPHP-----SPLTP 2977
Query: 681 EPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHL 726
PP T V+ + PPK + PP R S L
Sbjct: 2978 LPPLLVCPTATVANTVTTVT-ISTSPPKRKRGRPPKNPPSPRPSQL 3022
Score = 36.6 bits (83), Expect = 0.13
Identities = 44/177 (24%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 488 PEPPDTGVSHLCPEPPKTRVSH-LRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHL 546
P+PP P+P K +V+ L+P P + G + + P+ + + PP
Sbjct: 981 PDPPPR------PKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA 1034
Query: 547 RPEPPETGVSHLRPEP---PKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETG- 602
+P P P P P + M S P P + P P LPP P +G
Sbjct: 1035 QPTPG--------PVPQVLPASLMVSASPAGPPLIPASRPPGPVL-----LPPLQPNSGS 1081
Query: 603 VSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPP 659
+ + P P RP P L+P PP S P P ++ + PP
Sbjct: 1082 LPQVLPSPLGVLSGTSRPPTPTLS---LKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135
Score = 36.2 bits (82), Expect = 0.16
Identities = 47/212 (22%), Positives = 68/212 (32%), Gaps = 37/212 (17%)
Query: 620 PEPPETGVSHLRPEPPKTRMYS-LRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHL 678
P+PP RP+P K ++ L+P P G + + P+ + +P PP
Sbjct: 981 PDPPP------RPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA 1034
Query: 679 CPEP---PETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEP----- 730
P P P+ + L G + P V +P + + P P
Sbjct: 1035 QPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLS 1094
Query: 731 ----PETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSL 786
P T L+P PP P L P PP S L P P
Sbjct: 1095 GTSRPPTPTLSLKPTPPAP--------------VRLSPAPPPGSSSLLKPLTVPPG---- 1136
Query: 787 HLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTK 818
+ PP +S T V + P P +
Sbjct: 1137 YTFPPAAATTTSTTTATATTTAVPAPTPAPQR 1168
Score = 31.2 bits (69), Expect = 5.3
Identities = 37/136 (27%), Positives = 43/136 (31%), Gaps = 19/136 (13%)
Query: 680 PEPPETRVSH-LRPEPPETGVSRLHP----EPPKTRVSSLHAEPPESRVSHLCPEPPETG 734
PE P TRVS LR ET + P ++ + P RV P P T
Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTP 2447
Query: 735 VSH------LRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHL 788
S L P P V P P+ H+ P PP P P SS
Sbjct: 2448 ASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPP--------PPSQIPPCSSPAC 2499
Query: 789 EPPKTRRVSSLRLEPP 804
PP PP
Sbjct: 2500 TPPPACTPPPAHTPPP 2515
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 74.7 bits (182), Expect = 4e-13
Identities = 135/559 (24%), Positives = 188/559 (33%), Gaps = 85/559 (15%)
Query: 276 GTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLH--PE 333
G G + PP RV H P P+ PP+ + P G S P
Sbjct: 963 GAGTTRSPGSPPTLRV-HGDTGSPRKPWPER--RPPRPAATRTAPPTPSPGPSASPGPPG 1019
Query: 334 PPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPE 393
P T SS P S + P+T SP P S P+ T P
Sbjct: 1020 PALTSDSSRELTPHSALTSEATSDAPDT--SP----PTPDPASRTNPDLILTS-PDFALS 1072
Query: 394 TPKNGVSP-LFPEPPKTRISNLRSEPPKIGVSHLCLEPPK-TRGSHLRPEPPETGVSHLR 451
TP + V P L PEP T + L E L +P + + L P + S
Sbjct: 1073 TPDSSVVPALTPEPSPTPLPTLPKE--------LTSDPSTPSEVTSLSPTSEQVPESDTT 1124
Query: 452 PEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLR 511
P+ T SS E + P P + P+P T + P P T
Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTT 1184
Query: 512 PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSH--LRPEPPETGVSHLRPEP-----PK 564
P P+ S + P+P P ++++H + P+P T P+P P
Sbjct: 1185 PHPTTITHSTMIPDPTTT-------PQPFTTITHSTMIPDPTTT------PQPFTTMQPT 1231
Query: 565 TRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPE 624
T +S P P T P P S++ P+P T P+P T P P
Sbjct: 1232 TTPHSTTPHPTTT------PHPTTITHSTMIPDPTTT------PQPFTTMQPTTMPHPTT 1279
Query: 625 TGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPE 684
T P P T + P P T + P+P T + P+P T P+P
Sbjct: 1280 T------PHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTT-PHPTTPDPSS 1332
Query: 685 TRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPK 744
T V P G P T SLH + ++ P P T S + P
Sbjct: 1333 TPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQ-----LTFTAP-APHTSTSQIPTLEPS 1386
Query: 745 PRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPP 804
P + S P T S +P T + PR S +L PP T P
Sbjct: 1387 PALES-SPSRSSTATS---MDPLST------EDFKPPRSQSPNLTPPPT--------HTP 1428
Query: 805 KTGRVSSLCPEPTKTGASH 823
+ ++ P+P + +H
Sbjct: 1429 HSASDLTVSPDPLLSPTAH 1447
Score = 65.1 bits (157), Expect = 3e-10
Identities = 92/378 (24%), Positives = 135/378 (35%), Gaps = 54/378 (14%)
Query: 169 EKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEP------------PE 216
+ T D T P E+S R P+ S P P TP ++ P+P P
Sbjct: 1122 DTTPDLDTTPYSSTVSEYS-RSPDPSPS---PHPTTTPDPTMAPDPITTLNPTVTPHFPT 1177
Query: 217 TGVSHLRPQPPKTQVSSLHLEP-----PETGVSH--LRPEPPKTQVSSLHLEP---PETG 266
T P P S++ +P P T ++H + P+P T ++P P +
Sbjct: 1178 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237
Query: 267 VSHLYLEPPGTGVSH--LCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSE 324
H P T ++H + P+P T +P P P + P P+
Sbjct: 1238 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTT 1297
Query: 325 TGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPK 384
T + P+P T + P+P T P+P T V LP G P
Sbjct: 1298 TPHPTMTPDPTTTPYPTTTPDPTTT-PHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAP 1356
Query: 385 TRVPPLRPE---------TPKNGVSPLFPEP----PKTRISNLRSEPPKIGVSHLCLEPP 431
T P L P+ T + + L P P +R S S P +S +PP
Sbjct: 1357 TVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDP---LSTEDFKPP 1413
Query: 432 KTRGSHLRPEPPET--GVSHLRPEPPKTRVSSLH-LEPPETGVSHLCPEPPEKDVSH--- 485
+++ +L P P T S L P + H L+ P L P P + H
Sbjct: 1414 RSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPC 1473
Query: 486 LRPEPPDTGVSHLCPEPP 503
+ P PP V + EPP
Sbjct: 1474 VAPTPP---VRVMACEPP 1488
Score = 60.5 bits (145), Expect = 8e-09
Identities = 98/415 (23%), Positives = 144/415 (34%), Gaps = 53/415 (12%)
Query: 169 EKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPK 228
E T+ PT + P + +P T S E ++P S P P T + P P
Sbjct: 1107 EVTSLSPTSE-QVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPIT 1165
Query: 229 TQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSH--LCPEP 286
T ++ P T P P S++ +P T P T ++H + P+P
Sbjct: 1166 TLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTT-------PQPFTTITHSTMIPDP 1218
Query: 287 PKTRVSHLHREP---PETGVPDLCLEPPKSRVSH--LRPEPSETGVSHLHPEPPKTLVSS 341
T +P P + P P + ++H + P+P+ T P+P T+ +
Sbjct: 1219 TTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTT------PQPFTTMQPT 1272
Query: 342 LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSP 401
P P T P P T P + P+P T P P+ P P
Sbjct: 1273 TMPHPTTT------PHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPD-PTTTPHP 1325
Query: 402 LFPEPPKTRISNLRSEPPKIG--VSHLCLEPPKTRGSH----LRPEPPETGVSHLRP-EP 454
P+P T + S P +G +S L P H P T S + EP
Sbjct: 1326 TTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP 1385
Query: 455 PKTRVSSLHLEPPETGVSHLCPE---PPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLR 511
SS T + L E PP +L P P T P +
Sbjct: 1386 SPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHT--------PHSASDLTVS 1437
Query: 512 PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSH---LRPEPPETGVSHLRPEPP 563
P+P + +H PP + +L P +S H + P PP V + EPP
Sbjct: 1438 PDPLLSPTAHPLDHPP-LDPLTLGPTPGQSPGPHGPCVAPTPP---VRVMACEPP 1488
Score = 37.0 bits (84), Expect = 0.096
Identities = 67/279 (24%), Positives = 92/279 (32%), Gaps = 36/279 (12%)
Query: 168 QEKTTDEPTEP--GKYPCGEFSPRPPETRVSCLPPEPPKTPV------------SSLRPE 213
Q TT +PT P +P P S + P+P TP + P
Sbjct: 1223 QPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPH 1282
Query: 214 PPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLE 273
P T P P T ++ +P T P+P T + +P T V
Sbjct: 1283 PTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTP-DPSSTPVITTVSL 1341
Query: 274 PPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPS-ETGVSHLHP 332
P G P T LH P+ S++ L P P+ E+ S
Sbjct: 1342 PTSLGTELSSPTLAPTVKPSLH---PQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSST 1398
Query: 333 EPPKTLVSSLHPEPPETGVSHLCPEPPET--RVSPLRQLPPEAGVSHLCPEPPKTRVPPL 390
+S+ +PP + +L P P T S L P L P PPL
Sbjct: 1399 ATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPL----LSPTAHPLDHPPL 1454
Query: 391 RPET--PKNGVSP------LFPEPPKTRISNLRSEPPKI 421
P T P G SP + P PP + + EPP +
Sbjct: 1455 DPLTLGPTPGQSPGPHGPCVAPTPP---VRVMACEPPAL 1490
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 73.6 bits (179), Expect = 9e-13
Identities = 181/775 (23%), Positives = 253/775 (32%), Gaps = 148/775 (19%)
Query: 168 QEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPP 227
QE DE PG P RP S P P + PP G SH P P
Sbjct: 725 QEYLLDEGPAPGTPPR---EARPGRHGHSIKRASVPPVPGKPRQVLPP--GTSHFTP--P 777
Query: 228 KTQVSSLHLEPPETGVSH-LRPEPPKTQVSSLHLEPPETGVSHLYL--EPPGTGVSHLCP 284
+T + P G H P K + + L P E +S L P G +++ P
Sbjct: 778 QTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLP 837
Query: 285 EPPKTRVSHLHREPPE----TGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVS 340
+P + V P T VP LCL PP++ RP+ ++ + S
Sbjct: 838 QPVEGEVGPAAPGPAPPPVPTAVPTLCL-PPEADAEPGRPKKRAHSLN-------RYAAS 889
Query: 341 SLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPET----PK 396
PE E V P + G SH P R ++ P+
Sbjct: 890 DSEPERDELLVP--------AAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPR 941
Query: 397 NGVSPLFPEPPKTRIS-----NLRSEP-----PKIGVSHLCLEPPKTRGSHLRPEPPETG 446
P P PPK S NL EP P+ G+ L + R S L
Sbjct: 942 KKGPP--PPPPKRSSSALASANLADEPVPDAEPEDGL--LGVRAQCRRASDLAGSVDTGS 997
Query: 447 VSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTR 506
++ +SS+ G PPE H P P PEP +
Sbjct: 998 AGSVKSIAAMLELSSIG------GGGRAARRPPE---GHPTPRPAS-------PEPGRVA 1041
Query: 507 -----VSH---LRPEPSETGVSHLRPEPPKILVSSLHQAPPESS---------VSHLRPE 549
V H + P P L+++ + P ES+ RP
Sbjct: 1042 TVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPR 1101
Query: 550 PPETGVSHLRPEPP---------KTRMYSLRPEPPDTGV----SHLCPEPPKTRVSSLPP 596
P G + + P K R+ + + + + S PK + P
Sbjct: 1102 GPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGP 1161
Query: 597 EPPE-TGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLC 655
EPP V H T RP + G L P PP EPP T ++HL
Sbjct: 1162 EPPPPLSVYH-----NGTGTVRRRPASEQAGPPELPPPPPPA-------EPPPTDLAHLP 1209
Query: 656 PEPPKTRVSSLPPEPPETGVSHLCPEPPETR-VSHLRPEPPETGVSRLHPEPPKTRVSSL 714
P PP + P +PP + P+P T+ V L+ P T P P V
Sbjct: 1210 PLPPPEGEARKPAKPP------VSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRA 1263
Query: 715 HAEPPESRVSHLCPEPPETGVSHLR--------PEPPKPRVSSLRPEPLETRVSHLRPEP 766
H PP P PP T ++ P P S R P ++ P
Sbjct: 1264 HGTPPPVSPK---PPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPP--AALAKPPGTP 1318
Query: 767 PETGVSHLHPELPKPRVSSLHL--EPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHL 824
P G S P P P +LH+ +PP+ ++ P PE G S
Sbjct: 1319 PSLGASPAKP--PSPGAPALHVPAKPPRAAAAAAAAAAAPPAP------PEGASPGDSAR 1370
Query: 825 KELFQEGTSSTMECVSDSLQ------RRHTSRKLRDFKWAGDLGVNEESISSLFD 873
++L T C++ +LQ R+ ++ RD G + I S+FD
Sbjct: 1371 QKL-----EETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFD 1420
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/285 (22%), Positives = 91/285 (31%), Gaps = 68/285 (23%)
Query: 122 EAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKY 181
E+ + + P A G + PP L + G+ + + E P +
Sbjct: 1144 ESDTVKRRPKAKEREAGPEPPPPL------------SVYHNGTGTVRRRPASEQAGPPEL 1191
Query: 182 PCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQ-VSSLHLEPPE 240
P PP T ++ LPP PP + +PP + P+P TQ V L P
Sbjct: 1192 PPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPP------VSPKPVLTQPVPKLQGSPTP 1245
Query: 241 TGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPE 300
T P P +V H PP + P+PP PP
Sbjct: 1246 TSKKVPLPGPGSPEVKRAHGTPPP-----------------VSPKPP---------PPPT 1279
Query: 301 TGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPE 360
P + S + P PS +PP L +PP T PP
Sbjct: 1280 APKPVKAVAGLPSGSAGPSPAPSPA------RQPPAALA-----KPPGT--------PPS 1320
Query: 361 TRVSPLRQLPPEAGVSHLCPEPPK----TRVPPLRPETPKNGVSP 401
SP + P A H+ +PP+ P P G SP
Sbjct: 1321 LGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASP 1365
Score = 39.7 bits (91), Expect = 0.015
Identities = 63/267 (23%), Positives = 89/267 (33%), Gaps = 43/267 (16%)
Query: 478 PPEKDVSHLRPEPPDTGVSHLCPEPPKTRV--SHLRPE-------PSETGVSHLRPE--- 525
P +V + PP C P T S L E P+E G + +P
Sbjct: 623 PQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHL 682
Query: 526 PPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYS-LRPEPPDTGVSHLCP 584
PP ++ + H+ G P P +R L E P G
Sbjct: 683 PPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREA 742
Query: 585 EPPK----TRVSSLPPEPPET------GVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP 634
P + + +S+PP P + G SH P T+ RP P+ P P
Sbjct: 743 RPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKT---RPGSPQALGGPHGPAP 799
Query: 635 PKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
++ +P P L P SLP P G +++ P+P E V P P
Sbjct: 800 ATAKV---KPTP-----QLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGP 851
Query: 695 PETGVSRLHPEPPKTRVSSLHAEPPES 721
P P T V +L PPE+
Sbjct: 852 A--------PPPVPTAVPTL-CLPPEA 869
Score = 38.5 bits (88), Expect = 0.033
Identities = 50/193 (25%), Positives = 64/193 (33%), Gaps = 25/193 (12%)
Query: 595 PPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHL 654
P P +L E P P G S R P + PP G SH
Sbjct: 717 PSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPP--GTSHF 774
Query: 655 CPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSL 714
P P+T + P P G H P + ++P P L P SL
Sbjct: 775 TP--PQTPTKTRPGSPQALGGPH----GPAPATAKVKPTP-----QLLPPTERPMSPRSL 823
Query: 715 HAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHL 774
P +++ P+P E V P P P P+ T V L PPE +
Sbjct: 824 PQSPTHRGFAYVLPQPVEGEVGPAAPGP--------APPPVPTAVPTL-CLPPE---ADA 871
Query: 775 HPELPKPRVSSLH 787
P PK R SL+
Sbjct: 872 EPGRPKKRAHSLN 884
Score = 35.4 bits (80), Expect = 0.28
Identities = 75/294 (25%), Positives = 94/294 (31%), Gaps = 66/294 (22%)
Query: 406 PPKTRISNLRSEPPKIGVSHLCLEPPKT--RGSHLRPE-------PPETGV------SHL 450
P + + S PP C P T + S L E P E G SHL
Sbjct: 623 PQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHL 682
Query: 451 RPEPPKT--RVSSL-----HLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPP 503
P P T + SSL H+ + + P P P +L E P
Sbjct: 683 PPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSS---------PMSRSQEYLLDEGP 733
Query: 504 KTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPP 563
P G S R P + PP SH P P+T P
Sbjct: 734 APGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPP--GTSHFTP--PQT--------PT 781
Query: 564 KTRMYSLR----PEPPDTGVSHLCPEP---PKTR----VSSLPPEPPETGVSHLCPEPPE 612
KTR S + P P + + P P P T SLP P G +++ P+P E
Sbjct: 782 KTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVE 841
Query: 613 TRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSL 666
V P P P P T + +L PP P PK R SL
Sbjct: 842 GEVGPAAPGP--------APPPVPTAVPTL-CLPPEADAE---PGRPKKRAHSL 883
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,919,353
Number of Sequences: 37866
Number of extensions: 5304562
Number of successful extensions: 31188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 994
Number of HSP's that attempted gapping in prelim test: 14888
Number of HSP's gapped (non-prelim): 8274
length of query: 1035
length of database: 18,247,518
effective HSP length: 112
effective length of query: 923
effective length of database: 14,006,526
effective search space: 12928023498
effective search space used: 12928023498
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.