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Search of human proteins with 61835164
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61835164 fragile X mental retardation-related protein 1
isoform b [Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61835164 fragile X mental retardation-related protein 1 isofo... 1083 0.0
gi|61835148 fragile X mental retardation-related protein 1 isofo... 1071 0.0
gi|61835172 fragile X mental retardation-related protein 1 isofo... 893 0.0
gi|4758410 fragile X mental retardation syndrome related protein... 713 0.0
gi|4503765 fragile X mental retardation 1 [Homo sapiens] 508 e-144
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 43 8e-04
gi|17402900 far upstream element-binding protein [Homo sapiens] 42 0.002
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 40 0.005
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.007
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.007
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.007
gi|239048862 checkpoint with forkhead and ring finger domains is... 39 0.009
gi|239048792 checkpoint with forkhead and ring finger domains is... 39 0.009
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 38 0.027
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 38 0.027
gi|194097341 period 1 [Homo sapiens] 37 0.035
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 37 0.035
gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens] 37 0.046
gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens] 37 0.046
gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens] 37 0.046
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 37 0.046
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 37 0.046
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 36 0.10
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 35 0.13
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 35 0.13
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 35 0.13
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 35 0.13
>gi|61835164 fragile X mental retardation-related protein 1 isoform
b [Homo sapiens]
Length = 539
Score = 1083 bits (2800), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60
MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
Sbjct: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60
Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120
EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
Sbjct: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120
Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180
VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
Sbjct: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180
Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240
VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
Sbjct: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240
Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300
IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
Sbjct: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300
Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360
GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
Sbjct: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360
Query: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420
VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
Sbjct: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420
Query: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480
DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
Sbjct: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480
Query: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD 539
DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
Sbjct: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD 539
>gi|61835148 fragile X mental retardation-related protein 1 isoform
a [Homo sapiens]
Length = 621
Score = 1071 bits (2769), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60
MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
Sbjct: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60
Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120
EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
Sbjct: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120
Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180
VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
Sbjct: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180
Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240
VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
Sbjct: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240
Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300
IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
Sbjct: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300
Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360
GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
Sbjct: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360
Query: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420
VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
Sbjct: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420
Query: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480
DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
Sbjct: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480
Query: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534
DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL
Sbjct: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534
>gi|61835172 fragile X mental retardation-related protein 1 isoform
c [Homo sapiens]
Length = 536
Score = 893 bits (2307), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 86 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 145
MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN
Sbjct: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
Query: 146 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 205
AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA
Sbjct: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
Query: 206 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 265
TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY
Sbjct: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
Query: 266 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 325
GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK
Sbjct: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
Query: 326 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 385
LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG
Sbjct: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300
Query: 386 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 445
RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR
Sbjct: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360
Query: 446 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 505
GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR
Sbjct: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420
Query: 506 SRRRRTDEDAVLMDGMTESDTASVNENGL 534
SRRRRTDEDAVLMDGMTESDTASVNENGL
Sbjct: 421 SRRRRTDEDAVLMDGMTESDTASVNENGL 449
>gi|4758410 fragile X mental retardation syndrome related protein 2
[Homo sapiens]
Length = 673
Score = 713 bits (1840), Expect = 0.0
Identities = 376/577 (65%), Positives = 435/577 (75%), Gaps = 60/577 (10%)
Query: 4 LTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGD 63
L VEVRGSNGAFYKGF+KDVHEDS+T+ FENNWQ ERQ+PF +VRLPPP D KEI+EGD
Sbjct: 14 LPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGD 73
Query: 64 EVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKK 123
EVEVYSRAN+QEPCGWWLA+VRMMKG+FYVIEYAACDATYNEIVT ERLRPVN N K
Sbjct: 74 EVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATK 133
Query: 124 NTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNI 183
+FFK T+ VPEDLREAC+NEN HK+FKKA+GA IF + ++L ILS +EA VKR ++
Sbjct: 134 GSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASL 193
Query: 184 LSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQ 243
L DMH RS+RTKL+LMSRNEEATKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQ
Sbjct: 194 LGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQ 253
Query: 244 ARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKV 303
ARKVPGVTAIEL E+T TFRIYGE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKV
Sbjct: 254 ARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKV 313
Query: 304 IQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQ 363
IQEIVDKSGVVRVR+EGDN+ K PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQ
Sbjct: 314 IQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQ 373
Query: 364 LRMERLQIDEQLRQIG------------------------------------SRSYSGRG 387
LR+ERLQIDEQLRQIG SY GRG
Sbjct: 374 LRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRG 433
Query: 388 RGRR--GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGG 444
RGRR GP YG +S++S SETESE+++E + AG DRD +SRRRP
Sbjct: 434 RGRRTGGP----AYGPSSDVSTASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-- 484
Query: 445 RGRSVSGGRGRGGP-------RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESH 497
+GGRGRG P R SSISSVLKDPDSNPYSLLD +E + D++ E
Sbjct: 485 -----TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPP 539
Query: 498 HSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534
++ RRRRSRRRRTDED +MDG ESD ++ ENGL
Sbjct: 540 PASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGL 576
>gi|4503765 fragile X mental retardation 1 [Homo sapiens]
Length = 632
Score = 508 bits (1307), Expect = e-144
Identities = 247/334 (73%), Positives = 283/334 (84%)
Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60
M EL VEVRGSNGAFYK F+KDVHEDS+TV FENNWQP+RQ+PF++VR PPP K+I+
Sbjct: 1 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN 60
Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120
E DEVEVYSRAN++EPC WWLAKVRM+KGEFYVIEYAACDATYNEIVT ERLR VN NK
Sbjct: 61 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP 120
Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180
K+TF K +DVPEDLR+ CA E AHKDFKKAVGA + Y PE QL+ILS +E T KR
Sbjct: 121 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR 180
Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240
++L DMH RS+RTKL L+ RNEEA+K LE ++QLA+ FHE+F+VREDLMGLAIGTHG+N
Sbjct: 181 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN 240
Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300
IQQARKVPGVTAI+LDEDT TF IYGE DAVKKAR FLEF ED IQVPRNLVGKVIGKN
Sbjct: 241 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN 300
Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVP 334
GK+IQEIVDKSGVVRVRIE +NE +P+E+ ++P
Sbjct: 301 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMP 334
Score = 162 bits (409), Expect = 9e-40
Identities = 132/350 (37%), Positives = 166/350 (47%), Gaps = 74/350 (21%)
Query: 219 FHEEFV-VREDLMGLAIGTHGSNIQQARKVPGVTAIELDED------------------T 259
F E+ + V +L+G IG +G IQ+ GV + ++ + +
Sbjct: 281 FAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPS 340
Query: 260 GTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIE 319
R+ G +A KK E F Q N +Q ++ S VV
Sbjct: 341 NNSRV-GPNAPEEKKHLDIKENSTHFSQ-----------PNSTKVQRVLVASSVVA---- 384
Query: 320 GDNEN-KLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQI 378
G+++ +L GMVPFVFVGTK+SI N VLL+YH+ YLKEV+QLR+ERLQIDEQLRQI
Sbjct: 385 GESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQI 444
Query: 379 ---------------------------GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSET 411
GSR Y RG GRRGP YTS GTNSE SN SET
Sbjct: 445 GASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTS--GTNSEASNASET 502
Query: 412 ESERKDELSDWSLA-GEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLK 470
ES+ +DELSDWSLA E++R+S +R RR GG GR GGRGRGG G S
Sbjct: 503 ESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG-QGGRGRGGGFKGNDDHSRTDN 561
Query: 471 DPDSNPYSLLDNTESDQ---TADTDASESHHS---TNRRRRSRRRRTDED 514
P NP T D + S H+ N R RT +D
Sbjct: 562 RP-RNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKD 610
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 42.7 bits (99), Expect = 8e-04
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 33/135 (24%)
Query: 357 YLKEVEQLRMERLQIDEQLRQIGSRS----YSGRG-----RGRRGPNYTSGYGTNSELSN 407
+ KE+ Q R + + R GSR Y GRG RGR + G G S +
Sbjct: 220 FTKELNQYRRAK---EGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGD 276
Query: 408 PSETESERKDELSDWSLA----GEDDRDS--------RHQRDSRRR---------PGGRG 446
E E + +E D+ + G+DD D R +DSR R GRG
Sbjct: 277 HPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGRG 336
Query: 447 RSVSGGRGRGGPRGG 461
+ + GRGRGG RGG
Sbjct: 337 KGMGRGRGRGGSRGG 351
Score = 32.7 bits (73), Expect = 0.86
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 12/113 (10%)
Query: 410 ETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG--------- 460
E E K++ D++ R ++ R GRGR G RGG RG
Sbjct: 208 EEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRG 267
Query: 461 -GKSSISSVLKDPDSNPY-SLLDNTESDQ-TADTDASESHHSTNRRRRSRRRR 510
G+ S+ + + + Y +D ES++ D D E N+ RRS+ R
Sbjct: 268 RGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSR 320
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 48/205 (23%)
Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDE---DTGT---FRIYGES------ 268
+E ++ GL IG G I+Q ++ GV + + + +TG RI G+
Sbjct: 188 QEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQA 247
Query: 269 ----ADAVKKARGFLEFVEDF-----------IQVPRNLVGKVIGKNGKVIQEIVDKSGV 313
+ ++ GF E ++ + +PR VG VIG+NG++I++I + +G
Sbjct: 248 KEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAG- 306
Query: 314 VRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDE 373
VR++ + D DG P Q E L+ V
Sbjct: 307 VRIQFKPD--------DGTTPERIAQITGPPDRCQHAAEIITDLLRSV------------ 346
Query: 374 QLRQIGSRSYSGRGRGRRGPNYTSG 398
Q G GRGRGR N+ G
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMG 371
Score = 37.7 bits (86), Expect = 0.027
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 24/135 (17%)
Query: 213 KQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFR----IYGES 268
+Q + EE+ V + ++G IG G I + ++ G I++ D+G + +
Sbjct: 95 QQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCK-IQIAPDSGGLPERSCMLTGT 153
Query: 269 ADAVKKARGFLEFVEDF-------------------IQVPRNLVGKVIGKNGKVIQEIVD 309
++V+ A+ L+ + + I +P + G VIGK G+ I+++ +
Sbjct: 154 PESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQE 213
Query: 310 KSGVVRVRIEGDNEN 324
++GV V I+ +N
Sbjct: 214 RAGVKMVMIQDGPQN 228
Score = 32.0 bits (71), Expect = 1.5
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 277 GFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFV 336
G EF +FI VP G +IGK G+ I+ I +SG RIE + M F
Sbjct: 375 GLQEF--NFI-VPTGKTGLIIGKGGETIKSISQQSG---ARIELQRNPPPNADPNMKLFT 428
Query: 337 FVGTKESIGNVQVLLEYHI 355
GT + I + L+E I
Sbjct: 429 IRGTPQQIDYARQLIEEKI 447
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 40.0 bits (92), Expect = 0.005
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 29/130 (22%)
Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDED---TGT---FRIYGESADAVKK 274
+E ++ +GL IG G I+Q ++ GV + + + TG RI G++ +
Sbjct: 165 QEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQA 224
Query: 275 ARGFLEFVE------------DF----------IQVPRNLVGKVIGKNGKVIQEIVDKSG 312
LE + DF + VPR VG VIG+NG++I++I + +G
Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAG 284
Query: 313 VVRVRIEGDN 322
VR++ + D+
Sbjct: 285 -VRIQFKPDD 293
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 283 EDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKE 342
E+F +VP +VG +IG+ G+ I I +SG +++I ++ R P V GT E
Sbjct: 80 EEF-KVPDKMVGFIIGRGGEQISRIQAESG-CKIQIASESSGIPER-----PCVLTGTPE 132
Query: 343 SIGNVQVLL 351
SI + LL
Sbjct: 133 SIEQAKRLL 141
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 346 NVQVLLEYHIAYLKEVE 362
N Q LL+ + +VE
Sbjct: 446 NAQYLLQNSVKQYADVE 462
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 346 NVQVLLEYHIAYLKEVE 362
N Q LL+ + +VE
Sbjct: 446 NAQYLLQNSVKQYADVE 462
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 39.7 bits (91), Expect = 0.007
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 11/160 (6%)
Query: 381 RSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSR------- 433
+S SG+G+ + +S +S+ S+ S+++S + SD + D DS
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598
Query: 434 -HQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTD 492
+ DS S S KS S D DS S D+ SD + ++D
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS--SDSDSKSDS-SDSNSSDSSDNSD 655
Query: 493 ASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 532
+S+S +S+N S + + + D SD++ +++
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Score = 38.9 bits (89), Expect = 0.012
Identities = 36/147 (24%), Positives = 55/147 (37%), Gaps = 3/147 (2%)
Query: 394 NYTSGYGTNSELSNPSETESERKDEL-SDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG 452
N + +NS S+ S S+ D S S D DS + DS S S
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 453 RGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTD 512
S S DS+ S D+++S ++D+D+S S S+N S +
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSS--DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 513 EDAVLMDGMTESDTASVNENGLGKRCD 539
+ + D SD+ S N + D
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Score = 37.0 bits (84), Expect = 0.046
Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
Query: 394 NYTSGYGTNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRDSRRRPGGRGRSVSG 451
N +S +S+ SN S+++S SD S + D +S + D+ S S
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Query: 452 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT-DASESHHSTNRRRRSRRRR 510
S+ S DS+ + D+++S ++D+ D+S+S S++ S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 511 TDEDAVLMDGMTESDTASVNEN 532
+ + + D SD+++ +++
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDS 1027
Score = 35.8 bits (81), Expect = 0.10
Identities = 31/132 (23%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +SE S+ S++ + SD S + D DS + DS S S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD--- 748
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D ++ S + SD + +++S+S+ S+N S + + +
Sbjct: 749 ----SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 516 VLMDGMTESDTA 527
D SD++
Sbjct: 805 NSSDSSDSSDSS 816
Score = 35.4 bits (80), Expect = 0.13
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 9/171 (5%)
Query: 372 DEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDEL--SDWSLAGEDD 429
D++ Q + S G N S ++S + S E KD SD A +DD
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSR-GDASYNSDESKDNGNGSDSKGAEDDD 514
Query: 430 RDSRHQRDSRRRPG----GRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTES 485
DS ++ G G + G+G S S DS+ S D+++S
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 486 DQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGK 536
+ ++D+D+S+S S + S D+ D SD++ +++ K
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDS--SDSSDSSDSSDSSDSSDSK 623
Score = 35.0 bits (79), Expect = 0.17
Identities = 33/157 (21%), Positives = 65/157 (41%), Gaps = 4/157 (2%)
Query: 380 SRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRD 437
S S + + + +S + S+ S+ + ++S + SD S + D DS D
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 438 SRRRPGGRGRSVSGGRG--RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASE 495
S S S SS SS DS+ S ++++SD + +D+S+
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 496 SHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 532
S +S++ S + + + D SD++ +++
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 397 SGYGTNSELSNPSET-ESERKDELSDWSLAGE-DDRDSRHQRDSRRRPGGRGRSVSGGRG 454
S +S+ SN S++ +S + SD S + + D DS ++ DS S S
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 455 RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT-DASESHHSTNRRRRSRRRRTDE 513
+ S+ DS+ S D+++S ++D+ D+S S S+ S + +
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 514 DAVLMDGMTESDTASVNEN 532
+ D SD+++ +++
Sbjct: 938 SSNSSDSSDSSDSSNSSDS 956
Score = 34.7 bits (78), Expect = 0.23
Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 4/140 (2%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +SE S+ S++ S S D DS + DS S S
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 456 GGPRGGKSSISSVLKDPDSNPYS-LLDNTESDQTADT-DASESHHSTNRRRRSRRRRTDE 513
S S DS+ S D+++S++++D+ D+S+S S+N S +D
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS--DSSDS 1258
Query: 514 DAVLMDGMTESDTASVNENG 533
D ESD+ S + NG
Sbjct: 1259 SDSTSDSNDESDSQSKSGNG 1278
Score = 34.3 bits (77), Expect = 0.30
Identities = 31/130 (23%), Positives = 51/130 (39%), Gaps = 2/130 (1%)
Query: 401 TNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRDSRRRPGGRGRSVSGGRGRGGP 458
++S+ S+ S+++S SD S + + D DS DS+ S +
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 459 RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLM 518
SS SS D + S + SD + +D+S S S+N S + +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 519 DGMTESDTAS 528
D SD+ S
Sbjct: 703 DSSDSSDSDS 712
Score = 33.5 bits (75), Expect = 0.51
Identities = 30/132 (22%), Positives = 51/132 (38%), Gaps = 2/132 (1%)
Query: 397 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 456
S +NS S+ S S+ + + D DS + DS S S
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 457 GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTAD-TDASESHHSTNRRRRSRRRRTDEDA 515
S S + SN D+++S ++D +D+S+S+ S+N S + D+
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS-SDS 903
Query: 516 VLMDGMTESDTA 527
D SD++
Sbjct: 904 DSSDSSNSSDSS 915
Score = 33.5 bits (75), Expect = 0.51
Identities = 31/139 (22%), Positives = 54/139 (38%), Gaps = 2/139 (1%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ SN S++ + S S D DS DS S S
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 456 GGPRGGKSSISSVLKDPDS-NPYSLLDNTESDQTAD-TDASESHHSTNRRRRSRRRRTDE 513
S S DS N D+++S ++D +D+S+S S++ S + +
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 514 DAVLMDGMTESDTASVNEN 532
+ D SD++ +E+
Sbjct: 1132 SSDSSDSSNSSDSSDSSES 1150
Score = 32.7 bits (73), Expect = 0.86
Identities = 27/137 (19%), Positives = 50/137 (36%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ SN S++ S S D DS + DS S S
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
S +S S+ ++++S ++D+ S+NR S + + +
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 516 VLMDGMTESDTASVNEN 532
+ SD++ NE+
Sbjct: 872 DSSNSSDSSDSSDSNES 888
Score = 32.7 bits (73), Expect = 0.86
Identities = 31/137 (22%), Positives = 51/137 (37%), Gaps = 1/137 (0%)
Query: 397 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 456
S G++S+ SN S++ + S S D DS +S S S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 457 -GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D + S ++ SD + +D+S+S S+N S + +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 516 VLMDGMTESDTASVNEN 532
D + + S N +
Sbjct: 967 DSSDSNSSDSSDSSNSS 983
Score = 32.3 bits (72), Expect = 1.1
Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 4/141 (2%)
Query: 394 NYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGR 453
N + +NS S+ S S+ D S S D DS + DS S S
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSD--SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 454 GRGGPRGGKSSISSVLKDPDSNPYS-LLDNTESDQTADT-DASESHHSTNRRRRSRRRRT 511
S S DS+ S D+++S ++D+ D+S+S S++ S +
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 512 DEDAVLMDGMTESDTASVNEN 532
E + D SD++ +++
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDS 1102
Score = 31.6 bits (70), Expect = 1.9
Identities = 30/137 (21%), Positives = 51/137 (37%), Gaps = 4/137 (2%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ S+ S++ S S D DS + DS S
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS----SDSSESSDSSDSS 1157
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D + S + SD + +D+S+S S++ S + + +
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217
Query: 516 VLMDGMTESDTASVNEN 532
D SD++ NE+
Sbjct: 1218 DSSDSSDSSDSSDSNES 1234
Score = 31.2 bits (69), Expect = 2.5
Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 3/138 (2%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ S+ S++ S S D DS DS S S
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT-DASESHHSTNRRRRSRRRRTDED 514
S S DS+ S D+++S ++D+ D+S+S S++ S + E
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 515 AVLMDGMTESDTASVNEN 532
+ D SD++ +++
Sbjct: 1151 SDSSDSSDSSDSSDSSDS 1168
Score = 30.8 bits (68), Expect = 3.3
Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 9/141 (6%)
Query: 396 TSGYGTNSELSNPSET----ESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG 451
+S ++S+ SN S++ +S E SD S D DS DS S +
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS--DSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 452 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT 511
SS SS + + S + SD + +D+S+S S+N + +
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 512 DEDAVLMDGMTESDTASVNEN 532
+ + D SD+++ +++
Sbjct: 792 SDSS---DSSNSSDSSNSSDS 809
Score = 30.8 bits (68), Expect = 3.3
Identities = 28/143 (19%), Positives = 53/143 (37%), Gaps = 7/143 (4%)
Query: 397 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 456
S +NS S+ S +E + + D DS +S S S
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 457 GPRGGKSSISSVLKDPDSNPYS-------LLDNTESDQTADTDASESHHSTNRRRRSRRR 509
S S+ DS+ S D++ S ++D+++S+S S+N S
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 510 RTDEDAVLMDGMTESDTASVNEN 532
+ + + D SD++ +++
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDS 1012
Score = 30.8 bits (68), Expect = 3.3
Identities = 29/138 (21%), Positives = 53/138 (38%), Gaps = 1/138 (0%)
Query: 396 TSGYGTNSELSNPSETE-SERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRG 454
+S +S+ SN S++ S + SD S + + S S S
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 455 RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDED 514
SS SS D ++ S + SD + +D+S S S+N S + +
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 515 AVLMDGMTESDTASVNEN 532
+ D SD+++ +++
Sbjct: 1043 SDSSDSSDSSDSSNSSDS 1060
Score = 30.8 bits (68), Expect = 3.3
Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 3/136 (2%)
Query: 397 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 456
S +NS S+ S S+ D S S D DS DS S S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 457 GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAV 516
SS SS D + S + SD + +D+S+S S++ S + + +
Sbjct: 1034 SD-SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 517 LMDGMTESDTASVNEN 532
D SD++ +++
Sbjct: 1093 SSDSSDSSDSSDSSDS 1108
Score = 30.8 bits (68), Expect = 3.3
Identities = 29/137 (21%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ S+ S++ S S D DS + DS S S
Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D ++ S + SD + +D+S+S S+ S + + +
Sbjct: 1039 SSD-SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 516 VLMDGMTESDTASVNEN 532
D SD++ +++
Sbjct: 1098 DSSDSSDSSDSSDSSDS 1114
Score = 30.4 bits (67), Expect = 4.3
Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 8/137 (5%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +SE SN S+ + S S D DS + DS S S
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDS---SDSSDSSNSSDSSNSSDSSNSSDSSDSN- 972
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D + S + SD + +D+S+S S++ S + + +
Sbjct: 973 ----SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 516 VLMDGMTESDTASVNEN 532
D SD++ +++
Sbjct: 1029 NSSDSSDSSDSSDSSDS 1045
Score = 30.0 bits (66), Expect = 5.6
Identities = 28/138 (20%), Positives = 53/138 (38%), Gaps = 1/138 (0%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S S+ SE+ + + S S D DS +S S S
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT-DASESHHSTNRRRRSRRRRTDED 514
S +S S+ D+++S ++D+ D+S+S S+N S +
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 515 AVLMDGMTESDTASVNEN 532
+ D SD++ +++
Sbjct: 1031 SDSSDSSDSSDSSDSSDS 1048
Score = 29.6 bits (65), Expect = 7.3
Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 9/145 (6%)
Query: 397 SGYGTNSELSNPSETESERKDEL-SDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
S +NS SN S S+ D S S D DS DS S S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS-------DSSNSSDSSN 828
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTE-SDQTADTDASESHHSTNRRRRSRRRRTDED 514
S+ S DS+ S D++ SD + +D+S+S S+N S ++E
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 515 AVLMDGMTESDTASVNENGLGKRCD 539
+ D S+++ + + D
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSD 913
Score = 29.3 bits (64), Expect = 9.5
Identities = 29/137 (21%), Positives = 51/137 (37%), Gaps = 1/137 (0%)
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455
+S +S+ S+ S++ S S D DS DS S S
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
SS SS D + S + SD + +D+S+S S++ S + + +
Sbjct: 1090 SS-NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 516 VLMDGMTESDTASVNEN 532
D SD++ +++
Sbjct: 1149 ESSDSSDSSDSSDSSDS 1165
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 39.3 bits (90), Expect = 0.009
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Query: 299 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 358
K+G+V E SG V +++ + P + G V ++ E NV L E L
Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123
Query: 359 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 418
E + + E + +++ G++ SG G GR G + + PS ++ E
Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173
Query: 419 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 467
S + D + + P GR RS S G G GG P+G S++S
Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 39.3 bits (90), Expect = 0.009
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Query: 299 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 358
K+G+V E SG V +++ + P + G V ++ E NV L E L
Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123
Query: 359 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 418
E + + E + +++ G++ SG G GR G + + PS ++ E
Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173
Query: 419 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 467
S + D + + P GR RS S G G GG P+G S++S
Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 37.7 bits (86), Expect = 0.027
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 384 SGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPG 443
SG GRG G ++G G++S S ++ E + G+ ++ RD + G
Sbjct: 495 SGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAG 554
Query: 444 GR----GRSVSGGRGRGGPRG 460
G G+ GG G GG +G
Sbjct: 555 GHGSGGGQRPGGGHGSGGGQG 575
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 10/87 (11%)
Query: 379 GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDS 438
G SG G+G RG G G+N + S ++ + + G H
Sbjct: 518 GGNQCSGEGQGSRG-----GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG 572
Query: 439 RRRPG-----GRGRSVSGGRGRGGPRG 460
+ PG G G++ GG+G G +G
Sbjct: 573 GQGPGDGHGSGGGKNSGGGKGSGSGKG 599
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 37.7 bits (86), Expect = 0.027
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 26/129 (20%)
Query: 383 YSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRP 442
Y R RGRR P+ Y N ESERK + + SR + +SR R
Sbjct: 373 YYSRLRGRRNPSPDHSYKRNG--------ESERKSSRHRGKKSHKRTSKSRERHNSRSRG 424
Query: 443 GGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNR 502
R RS RGRG +S + + + + +S S R
Sbjct: 425 RNRDRSRDRSRGRGSRSRSRS------------------RSRRSRRSRSQSSSRSRSRGR 466
Query: 503 RRRSRRRRT 511
RR R RT
Sbjct: 467 RRSGNRDRT 475
>gi|194097341 period 1 [Homo sapiens]
Length = 1290
Score = 37.4 bits (85), Expect = 0.035
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 13/140 (9%)
Query: 364 LRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWS 423
L++ LQ++E R G+ G G GP S E TES +D LS S
Sbjct: 982 LQLNLLQLEELPRAEGAAVAGGPGSSA-GPPPPSAEAAEPEARLAEVTESSNQDALSGSS 1040
Query: 424 -----LAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNP-- 476
L ED R S G G + G G G GG +S S S+
Sbjct: 1041 DLLELLLQEDSRSGTGSAAS----GSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSK 1096
Query: 477 -YSLLDNTESDQTADTDASE 495
+ +D++E++ A +E
Sbjct: 1097 YFGSIDSSEAEAGAARGGAE 1116
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 37.4 bits (85), Expect = 0.035
Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 28/131 (21%)
Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESA----DAVKKAR 276
EE+ V + ++GL IG G I + ++ G +++ D+G S ++V+KA+
Sbjct: 147 EEYRVPDGMVGLIIGRGGEQINKIQQDSGCK-VQISPDSGGLPERSVSLTGAPESVQKAK 205
Query: 277 GFLEFVEDF-----------------------IQVPRNLVGKVIGKNGKVIQEIVDKSGV 313
L+ + I +P G VIGK G+ I+++ +++GV
Sbjct: 206 MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGV 265
Query: 314 VRVRIEGDNEN 324
+ I+ ++N
Sbjct: 266 KMILIQDGSQN 276
Score = 35.0 bits (79), Expect = 0.17
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 27/128 (21%)
Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGT------FRIYGESADAVKK 274
+E ++ GL IG G I+Q ++ GV I + + + RI G+ +
Sbjct: 236 QEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQA 295
Query: 275 ARGFLEFVEDFIQ--------------------VPRNLVGKVIGKNGKVIQEIVDKSGVV 314
++ + + Q VPR+ VG VIG++G++I++I + +G V
Sbjct: 296 CEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAG-V 354
Query: 315 RVRIEGDN 322
R++ + D+
Sbjct: 355 RIQFKQDD 362
Score = 29.3 bits (64), Expect = 9.5
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 287 QVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGN 346
+VP +VG +IG+ G+ I +I SG +V+I D+ R + G ES+
Sbjct: 150 RVPDGMVGLIIGRGGEQINKIQQDSG-CKVQISPDSGGLPERSVSL-----TGAPESVQK 203
Query: 347 VQVLLE 352
+++L+
Sbjct: 204 AKMMLD 209
>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
Length = 1164
Score = 37.0 bits (84), Expect = 0.046
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 12/144 (8%)
Query: 404 ELSNPSETESERKDELSDW---SLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG 460
E + +E ER D +D S+ G ++ S H +++ R SG RG GG
Sbjct: 981 EKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSS 1040
Query: 461 GKSSISSVLKDPD--SNPYS------LLDNTESDQTADTDASESHHSTNRRRRSRRRRTD 512
S +S+ K P + P+S + + + S T S + R R
Sbjct: 1041 SSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKS 1100
Query: 513 EDAVLMDGMTESDTASVNENGLGK 536
E DGMT S + S+ + LGK
Sbjct: 1101 ESQCDEDGMTSSLSESL-KTELGK 1123
>gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]
Length = 1113
Score = 37.0 bits (84), Expect = 0.046
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 12/144 (8%)
Query: 404 ELSNPSETESERKDELSDW---SLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG 460
E + +E ER D +D S+ G ++ S H +++ R SG RG GG
Sbjct: 930 EKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSS 989
Query: 461 GKSSISSVLKDPD--SNPYS------LLDNTESDQTADTDASESHHSTNRRRRSRRRRTD 512
S +S+ K P + P+S + + + S T S + R R
Sbjct: 990 SSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKS 1049
Query: 513 EDAVLMDGMTESDTASVNENGLGK 536
E DGMT S + S+ + LGK
Sbjct: 1050 ESQCDEDGMTSSLSESL-KTELGK 1072
>gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]
Length = 1163
Score = 37.0 bits (84), Expect = 0.046
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 12/144 (8%)
Query: 404 ELSNPSETESERKDELSDW---SLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG 460
E + +E ER D +D S+ G ++ S H +++ R SG RG GG
Sbjct: 980 EKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSS 1039
Query: 461 GKSSISSVLKDPD--SNPYS------LLDNTESDQTADTDASESHHSTNRRRRSRRRRTD 512
S +S+ K P + P+S + + + S T S + R R
Sbjct: 1040 SSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKS 1099
Query: 513 EDAVLMDGMTESDTASVNENGLGK 536
E DGMT S + S+ + LGK
Sbjct: 1100 ESQCDEDGMTSSLSESL-KTELGK 1122
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 37.0 bits (84), Expect = 0.046
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 6/67 (8%)
Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 346 NVQVLLE 352
N Q LL+
Sbjct: 446 NAQYLLQ 452
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 37.0 bits (84), Expect = 0.046
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 13/208 (6%)
Query: 339 GTKESIGNVQVLLEYHIAYLKEV--EQLRMERLQIDEQLRQIGSRSYS-GRGRGRRGPNY 395
GTK + Q E +A KE E++ E + DE+ R+ S GR + R
Sbjct: 216 GTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERS 275
Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG--- 452
L S++E E+K+ S +G D ++ R G+ +SG
Sbjct: 276 CKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSED 335
Query: 453 ---RGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRR 509
G+G P K S S S L+ SD A + + ++ SR+
Sbjct: 336 EEDSGKGEPT-AKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKG 394
Query: 510 RTDEDAVLMDGMTESDTASVNENGLGKR 537
RT + DG E A + G G+R
Sbjct: 395 RTRSSSSSSDGSPE---AKGGKAGSGRR 419
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 35.8 bits (81), Expect = 0.10
Identities = 47/168 (27%), Positives = 62/168 (36%), Gaps = 15/168 (8%)
Query: 357 YLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERK 416
Y + + R + + D + R+ SRS S GR R S SE N E S++
Sbjct: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR-RHESKDKSSKKHKSEEHNDKEHSSDKG 98
Query: 417 DELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG---RGRGGPRGGKSSISSVLKDPD 473
E + S GED RH+R R+ GR S S R R R K S S +
Sbjct: 99 RERLNSSENGED----RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK 154
Query: 474 SNPYSLLDNTESDQTAD-------TDASESHHSTNRRRRSRRRRTDED 514
S S ++ + S S H R RSR R D
Sbjct: 155 SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRD 202
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 35.4 bits (80), Expect = 0.13
Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 16/93 (17%)
Query: 379 GSRSYSGRGRGRRGPNYTSG----YGTNSELSNPSETESER--KDELSDWSLAGEDDRDS 432
G + GR RG +GP G G + NP + ER K E D G RD
Sbjct: 1922 GEKGNPGR-RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 1980
Query: 433 RHQRDSRRRPGGRGRS-VSGGRGRGGPRGGKSS 464
PGG G + +GG GR GP G K +
Sbjct: 1981 V--------PGGPGETGKNGGFGRRGPPGAKGN 2005
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 35.4 bits (80), Expect = 0.13
Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 16/93 (17%)
Query: 379 GSRSYSGRGRGRRGPNYTSG----YGTNSELSNPSETESER--KDELSDWSLAGEDDRDS 432
G + GR RG +GP G G + NP + ER K E D G RD
Sbjct: 2128 GEKGNPGR-RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 2186
Query: 433 RHQRDSRRRPGGRGRS-VSGGRGRGGPRGGKSS 464
PGG G + +GG GR GP G K +
Sbjct: 2187 V--------PGGPGETGKNGGFGRRGPPGAKGN 2211
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 35.4 bits (80), Expect = 0.13
Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 16/93 (17%)
Query: 379 GSRSYSGRGRGRRGPNYTSG----YGTNSELSNPSETESER--KDELSDWSLAGEDDRDS 432
G + GR RG +GP G G + NP + ER K E D G RD
Sbjct: 1521 GEKGNPGR-RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 1579
Query: 433 RHQRDSRRRPGGRGRS-VSGGRGRGGPRGGKSS 464
PGG G + +GG GR GP G K +
Sbjct: 1580 V--------PGGPGETGKNGGFGRRGPPGAKGN 1604
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 35.4 bits (80), Expect = 0.13
Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 6/122 (4%)
Query: 401 TNSELSNP-SETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPR 459
+N + SN S ++S S + SR + SR + RS S R R R
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
Query: 460 GGKSSISSVLKDPDSNP----YSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515
G KS SS S+P YS ++ ++ S S S +R++R R R+ E
Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYS-SSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQ 311
Query: 516 VL 517
V+
Sbjct: 312 VI 313
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 366 MERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE---LSDW 422
+ER + D + + G + RG+ G + + E+E E +DE LS +
Sbjct: 115 IEREESDGEYDEFGRKKKKYRGKA-------VGPASILKEVEDKESEGEEEDEDEDLSKY 167
Query: 423 SLAGEDDRD----SRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYS 478
L ++D D S++ D+ + S R R R S SS P S+
Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDS-NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR 226
Query: 479 LLDNTESDQTADTDASESHHSTNRRRRSRRR 509
+ S ++ + + S +R R S+ R
Sbjct: 227 SRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,851,670
Number of Sequences: 37866
Number of extensions: 988125
Number of successful extensions: 4869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 4168
Number of HSP's gapped (non-prelim): 699
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.