Guide to the Human Genome
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Name: TSC1 Sequence: fasta or formatted (1163aa) NCBI GI: 241666462
Description:

tuberous sclerosis 1 protein isoform 3

Referenced in:

mTOR Pathway
Ras

Other entries for this name:
alt prot [1113aa] tuberous sclerosis 1 protein isoform 4
alt prot [1164aa] tuberous sclerosis 1 protein isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         66           3
 C cysteine            1.5         17           2
 D aspartate           5.2         61           2
 E glutamate           8.3         96           3
 F phenylalanine       2.2         26           2
 G glycine             5.5         64           4
 H histidine           4.1         48           2
 I isoleucine          2.8         33           1
 K lysine              6.1         71           2
 L leucine            12.0        139           4
 M methionine          2.5         29           2
 N asparagine          2.8         33           2
 P proline             7.1         83           3
 Q glutamine           5.2         61           3
 R arginine            5.2         60           2
 S serine             10.0        116           6
 T threonine           6.0         70           2
 V valine              4.9         57           3
 W tryptophan          0.6          7           1
 Y tyrosine            2.2         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tuberous sclerosis 1 protein isoform 3 
TSC1                  0.998   tuberous sclerosis 1 protein isoform 1 
TSC1                  0.945   tuberous sclerosis 1 protein isoform 4 
EEA1                  0.021   early endosome antigen 1, 162kD 
CGN                   0.019   cingulin 
SMC1A                 0.019   structural maintenance of chromosomes 1A 
GRIPAP1               0.017   GRIP1 associated protein 1 isoform 1 
FAM184B               0.016   hypothetical protein LOC27146 
LOC727832             0.016   golgi autoantigen, golgin subfamily a-like 
CLIP1                 0.016   restin isoform b 
CLIP1                 0.016   restin isoform a 
MYH10                 0.016   myosin, heavy polypeptide 10, non-muscle 
INCENP                0.016   inner centromere protein antigens 135/155kDa isofor...
GRIPAP1               0.016   GRIP1 associated protein 1 isoform 2 
INCENP                0.015   inner centromere protein antigens 135/155kDa isofor...
GOLGA6D               0.015   golgi autoantigen, golgin subfamily a, 6D 
GOLGA6C               0.015   PREDICTED: golgi autoantigen, golgin subfamily a, 6C...
LOC645202             0.015   PREDICTED: hypothetical protein LOC645202 
LOC283767             0.015   golgi autoantigen, golgin subfamily a-like 
LOC440243             0.015   PREDICTED: Putative golgin subfamily A member 6-lik...
PLEC1                 0.015   plectin 1 isoform 11 
PLEC1                 0.015   plectin 1 isoform 10 
PLEC1                 0.015   plectin 1 isoform 8 
PLEC1                 0.015   plectin 1 isoform 7 
PLEC1                 0.015   plectin 1 isoform 6 
PLEC1                 0.015   plectin 1 isoform 3 
PLEC1                 0.015   plectin 1 isoform 2 
PLEC1                 0.015   plectin 1 isoform 1 
LOC727909             0.014   PREDICTED: similar to Golgin subfamily A member 8-l...
CCDC18                0.014   sarcoma antigen NY-SAR-41 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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