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Search of human proteins with 13540614
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540614 coiled-coil domain containing 130 [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540614 coiled-coil domain containing 130 [Homo sapiens] 809 0.0
gi|31542652 coiled-coil domain containing 94 [Homo sapiens] 95 1e-19
gi|148746195 trichohyalin [Homo sapiens] 41 0.002
gi|18426913 drebrin 1 isoform b [Homo sapiens] 40 0.003
gi|18426915 drebrin 1 isoform a [Homo sapiens] 40 0.003
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.008
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 39 0.011
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.014
gi|50345881 cytoplasmic polyadenylation element binding protein ... 38 0.018
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 38 0.018
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 37 0.024
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 37 0.024
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 37 0.031
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 37 0.031
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 37 0.041
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 36 0.053
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 36 0.053
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 36 0.053
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 36 0.053
gi|55741677 SET domain containing 1A [Homo sapiens] 36 0.053
gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sa... 36 0.053
gi|148612801 KIAA1009 protein [Homo sapiens] 36 0.069
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ... 35 0.091
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ... 35 0.091
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ... 35 0.091
gi|52485606 formin-like 2 [Homo sapiens] 35 0.091
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 35 0.091
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 35 0.091
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 35 0.091
gi|154800453 tastin isoform 1 [Homo sapiens] 35 0.091
>gi|13540614 coiled-coil domain containing 130 [Homo sapiens]
Length = 396
Score = 809 bits (2090), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK 60
MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK
Sbjct: 1 MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK 60
Query: 61 NHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEE 120
NHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEE
Sbjct: 61 NHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEE 120
Query: 121 RWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDF 180
RWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDF
Sbjct: 121 RWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDF 180
Query: 181 ALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYE 240
ALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYE
Sbjct: 181 ALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYE 240
Query: 241 DKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRS 300
DKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRS
Sbjct: 241 DKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRS 300
Query: 301 RDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKP 360
RDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKP
Sbjct: 301 RDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKP 360
Query: 361 LSPAGSSQEAADTPDTRHPCSLGSSLVADYSDSESE 396
LSPAGSSQEAADTPDTRHPCSLGSSLVADYSDSESE
Sbjct: 361 LSPAGSSQEAADTPDTRHPCSLGSSLVADYSDSESE 396
>gi|31542652 coiled-coil domain containing 94 [Homo sapiens]
Length = 323
Score = 95.1 bits (235), Expect = 1e-19
Identities = 65/232 (28%), Positives = 111/232 (47%), Gaps = 18/232 (7%)
Query: 1 MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK 60
M ERK +NKYYPPDF+P K L + ++R P+N+ C C
Sbjct: 1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQ-------------YVVRLMAPFNMRCKTCG 47
Query: 61 NHIGMGVRYNAEKKKVGN--YYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRK 118
+I G ++NA K+ V N Y PI+RF +KC C+ I +TDP N DY + GA R
Sbjct: 48 EYIYKGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRN 107
Query: 119 EERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQE--AQSAW 176
+ + + E+ + + ++L + M LE+ D + L L +++ + A
Sbjct: 108 FQAEKLLEEEEKRVQKEREDEEL-NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAH 166
Query: 177 KDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLA 228
D A+ R E+++ QEE+E++ A + + L+ +++ + + A
Sbjct: 167 VDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAA 218
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/171 (25%), Positives = 75/171 (43%), Gaps = 25/171 (14%)
Query: 116 QRKEERWDMADNEQVLTTEHEKK--QKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQ 173
+R+EER +Q L E E++ Q+L+ + + RLE E LK+ P Q+
Sbjct: 580 KREEER-----RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 174 SAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKF 233
+ + + LRR +E+++ + EE ++ L+ + L E E++R+ L
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR------LKREHEEERREQELA-- 686
Query: 234 HTLDSYEDKQKLKRTEIISR----SWFPSAPGSASSSKVSGVLKKLAQSRR 280
E++Q+ R I SR W + A SKV +K RR
Sbjct: 687 ------EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Score = 35.4 bits (80), Expect = 0.091
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHG-EADRSTLKKALPTLSHIQEAQS 174
Q +EE + EQ+L E EK+++ E + +R E + + L + P QE +
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 175 AWKDDFALNSMLRRRFREKKKAIQEEEER 203
++++ L + RE+++ ++E ER
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERER 1197
Score = 34.3 bits (77), Expect = 0.20
Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 5/138 (3%)
Query: 114 GAQRKEERWDMADNEQVLTTEHEKKQ--KLETDAMFRLEHGEADRSTLKKALPTLSHIQE 171
G QR+++R E+ L E E++Q + E D FRLE + R ++
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
Query: 172 AQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALL 231
Q + L R+FRE ++ +QE EE+ Q + + P+ + L
Sbjct: 1606 RQEGQQQ---LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 232 KFHTLDSYEDKQKLKRTE 249
E++Q L+ E
Sbjct: 1663 HDRDRKFREEEQLLQEGE 1680
Score = 34.3 bits (77), Expect = 0.20
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 19/142 (13%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHG---EADRSTLKKALPTLSHIQEA 172
+++ +R + + Q+ E E++ + + D FR E E + L++ QE
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR--------QER 1689
Query: 173 QSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDR-----KL 227
++++ LRR+ RE+K +E++ R Q L+ K L ETE ++ +
Sbjct: 1690 DRKFREE---EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 228 AALLKFHTLDSYEDKQKLKRTE 249
+L+ L ++Q+L+R E
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQE 1768
Score = 32.3 bits (72), Expect = 0.77
Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 11/144 (7%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHG---EADRSTLKKALPTLSHIQEA 172
+ + ERW + E+ + ++Q+L + R E + + L++ L + ++
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 173 QSAWKDDFALNS---MLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAA 229
Q ++ L + RE++ ++EE RDQ L+ + + + E + +L
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL-KREQEERLEQ 600
Query: 230 LLKFHTLDSYED----KQKLKRTE 249
LK ++ E +Q+LKR E
Sbjct: 601 RLKREEVERLEQEERREQRLKREE 624
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/92 (20%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRST----LKKALPTLSHIQE 171
+++ ER + + +Q+ E E++ + + D FR E + R ++ + +
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER 1444
Query: 172 AQSAWKDDFALNSMLRRRFREKKKAIQEEEER 203
+ +++ L R+FRE+++ +QE EE+
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Score = 31.2 bits (69), Expect = 1.7
Identities = 36/149 (24%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFR---LEHGEADRSTLKKALPTLSHIQEA 172
+R+E++ + ++ E ++ ++ E D FR L E +R L++ L Q
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE-QQLHRQQRQ 1530
Query: 173 QSAWKDDFALNSMLR---------RRFREKKKAIQEEEERD---QALQAKASLTIPLVPE 220
+ +++ L R R+FRE+++ QE EE+ Q K L V
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 221 TEDDRKLAALLKFHTLDSYEDKQKLKRTE 249
E +RK ED+Q+L+R E
Sbjct: 1591 QEQERKF-----------MEDEQQLRRQE 1608
Score = 30.8 bits (68), Expect = 2.2
Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 10/99 (10%)
Query: 117 RKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHG-EADRSTLKKALPTLSHIQEAQSA 175
RKE++ + E++ E EK+++ E + +R E + + L + QE +
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 176 WKDDFALNSM---------LRRRFREKKKAIQEEEERDQ 205
++ D L +RR +E++K +EEEE Q
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Score = 30.0 bits (66), Expect = 3.8
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Query: 117 RKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAW 176
++EE + E VL E EK Q+ E L+ E L++ L ++ +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQ 296
Query: 177 KDDFALNSMLRRRFREKKKAIQEEEERDQ 205
+ LRR+ E+++ Q+EE R+Q
Sbjct: 297 QQRLRREQQLRRKQEEERRE-QQEERREQ 324
Score = 30.0 bits (66), Expect = 3.8
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 17/104 (16%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHG-EADRSTLKKALPTLSHIQEAQS 174
Q +EE + EQ+L E E +++ E + +R E + + L + P QE +
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 175 AWKDDFAL----------------NSMLRRRFREKKKAIQEEEE 202
+++ L L R++RE+++ QEEE+
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Score = 29.6 bits (65), Expect = 5.0
Identities = 23/109 (21%), Positives = 45/109 (41%), Gaps = 19/109 (17%)
Query: 116 QRKEERWD---------MADNEQVLTTEHEKKQKLETDAMFRLEH----------GEADR 156
+R+ + W+ + EQ+L E EK++ E + +R E GE
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 157 STLKKALPTLSHIQEAQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQ 205
+ ++ L +E ++ +RR +E+++ +EEEE Q
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Score = 29.3 bits (64), Expect = 6.5
Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 22/140 (15%)
Query: 116 QRKEERWDMADNE--QVLTTEHE-KKQKLETDAMFRLEH---GEADRSTLKKALPTLSHI 169
Q++ +R D E Q+L E E K+++ ETD FR E E + L++
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR-------- 1355
Query: 170 QEAQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAA 229
QE ++++ + R+F E+++ ++ +E + L+ + L E E +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR---CQEREQQLRQDR 1412
Query: 230 LLKFHTLDSYEDKQKLKRTE 249
KF E++Q+L R E
Sbjct: 1413 DRKFR-----EEEQQLSRQE 1427
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 40.4 bits (93), Expect = 0.003
Identities = 64/273 (23%), Positives = 98/273 (35%), Gaps = 67/273 (24%)
Query: 118 KEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWK 177
+E+ W+ A E+ L E E+K+ L+ F E E +R QE +
Sbjct: 179 REQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQER-------------QEQEER-- 223
Query: 178 DDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLD 237
RR+RE+++ I+E + Q L+A+ E R+L F
Sbjct: 224 ---------ERRYREREQQIEEHRRKQQTLEAE-----------EAKRRLKEQSIFGDHR 263
Query: 238 SYEDKQKLKRTE--------IIS------RSWFPS----APGSASSSKVSGVLKKLAQSR 279
E++ +K++E II+ R +F A SA S V S
Sbjct: 264 DEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSH 323
Query: 280 ---RTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDC 336
+A +PI S V E + A D S +P P+ P
Sbjct: 324 LDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQP---------PPLPPP-- 372
Query: 337 PPETTETPKCSSPRGQEGSRQDKPLSPAGSSQE 369
PP ET + S E +R P + AG +E
Sbjct: 373 PPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 405
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 40.4 bits (93), Expect = 0.003
Identities = 64/273 (23%), Positives = 98/273 (35%), Gaps = 67/273 (24%)
Query: 118 KEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWK 177
+E+ W+ A E+ L E E+K+ L+ F E E +R QE +
Sbjct: 177 REQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQER-------------QEQEER-- 221
Query: 178 DDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLD 237
RR+RE+++ I+E + Q L+A+ E R+L F
Sbjct: 222 ---------ERRYREREQQIEEHRRKQQTLEAE-----------EAKRRLKEQSIFGDHR 261
Query: 238 SYEDKQKLKRTE--------IIS------RSWFPS----APGSASSSKVSGVLKKLAQSR 279
E++ +K++E II+ R +F A SA S V S
Sbjct: 262 DEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSH 321
Query: 280 ---RTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDC 336
+A +PI S V E + A D S +P P+ P
Sbjct: 322 LDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQP---------PPLPPP-- 370
Query: 337 PPETTETPKCSSPRGQEGSRQDKPLSPAGSSQE 369
PP ET + S E +R P + AG +E
Sbjct: 371 PPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 403
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.9 bits (89), Expect = 0.008
Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 3/135 (2%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSA 175
Q+++ER + E L T+ +++ + +A +L + K +LP I E +
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451
Query: 176 WKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHT 235
K L S + E + E +Q + K P+ PE E+D + A L +
Sbjct: 452 KKIPQQLES---KEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEA 508
Query: 236 LDSYEDKQKLKRTEI 250
+ S E+ +K++ ++
Sbjct: 509 MASDEETEKVEGNKV 523
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 19/146 (13%)
Query: 115 AQRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADR----STLKK-------AL 163
A++KE D E+ + ++K++LET + + E+ R T+K +
Sbjct: 233 AEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVI 292
Query: 164 PTLSHIQEAQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETED 223
P E +A +DD N +++ +KKK ++EE+ + + + T+ + E
Sbjct: 293 PASEEKAETPTAAEDD---NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA-- 347
Query: 224 DRKLAALLKFHTLDSYEDKQKLKRTE 249
LA L + E+++++KR E
Sbjct: 348 ---LAKLKEEEERQKREEEERIKRLE 370
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 38.5 bits (88), Expect = 0.011
Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 9/138 (6%)
Query: 242 KQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDL---GIVRR 298
KQ + E + +W+ S SS V+ +LK L R+ + P +VG+L G+
Sbjct: 792 KQDRENEEGDTGNWYSSDEDEGGSS-VTSILKTL---RQQTSSRPPASVGELSSSGLGDP 847
Query: 299 RSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQD 358
R + + AD S +PR+ PGD P + EGS
Sbjct: 848 RLQKGHPTGSRLADPRLSRDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHS 907
Query: 359 KPLSPAGSSQEAADTPDT 376
P+ P SS + + P T
Sbjct: 908 SPVGP--SSSKGSGPPPT 923
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 38.1 bits (87), Expect = 0.014
Identities = 64/286 (22%), Positives = 108/286 (37%), Gaps = 27/286 (9%)
Query: 127 NEQVLTTEHEK---KQKLETDAMFRLEHGEADRSTLKKAL---PTLSHIQEAQSAWKDDF 180
N + LT + E+ + ++ + R G+ RS + L P+ S + ++S D
Sbjct: 1506 NNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDS 1565
Query: 181 ALNSM--LRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDS 238
+ LR+R R + + R ++++ + PE +D + A + + S
Sbjct: 1566 KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS----PEVKDKPRAAPRAQSGSDSS 1621
Query: 239 YEDKQ-------KLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALAT-SPITV 290
E K + R+ S+ PS GS+S+ K +RR + ++ P T
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681
Query: 291 GDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR 350
RR SR PE + A + +S +A P + PP +P SSP
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRS-------RSASSSPETRSRTPPRHRRSPSVSSPE 1734
Query: 351 GQEGSRQDKPLSPAGSSQEAADTPDTRHPCSLGSSLVADYSDSESE 396
E SR + A S + + R P L S S E
Sbjct: 1735 PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Score = 35.0 bits (79), Expect = 0.12
Identities = 67/297 (22%), Positives = 103/297 (34%), Gaps = 70/297 (23%)
Query: 133 TEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDFALNSMLRRRFRE 192
T +KK+K + D R E + R KK+ H E++S + + +R+ ++
Sbjct: 184 TPKQKKKKKKKDRGRRSE-SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKD 242
Query: 193 KKKAIQEEEE---RDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQKLKRTE 249
KK+ + + S +T R +A K HT T
Sbjct: 243 KKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT------------TA 290
Query: 250 IISRSWFP------------SAPGSASSSKVSGVLKKLAQ----------SRRTALATSP 287
+ RS P S PG+ S+ + S Q ++ AT P
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP 350
Query: 288 ITVGDLGIVRRRSRDVPE--------------SPQHAADTPKSGEP-RVPEEAAQDR--- 329
+ RS PE SPQ A TP S EP P EA+ R
Sbjct: 351 SPSPE------RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
Query: 330 -PMSPGDCPPETTETPKCSSPRGQEGSRQ-------DKPLSPAGSSQEAADTPDTRH 378
P SP P ++ SP+ + SR KP GS +E + +P +++
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461
Score = 29.3 bits (64), Expect = 6.5
Identities = 40/175 (22%), Positives = 63/175 (36%), Gaps = 16/175 (9%)
Query: 187 RRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYED----- 241
+RR RE K+ E + ++ +S P + + +K + + +
Sbjct: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS 213
Query: 242 KQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQS-------RRTALATSPITVGDLG 294
K+K R+E S+ +P S K +K ++S RR +TS +
Sbjct: 214 KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSD 273
Query: 295 IVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSP 349
R RSR A +S P D P S P TT T + SSP
Sbjct: 274 TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFS----EPGTTSTQRPSSP 324
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 37.7 bits (86), Expect = 0.018
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 11/101 (10%)
Query: 297 RRRSRDVPESP-QHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGS 355
R++ + PES A TP S E PEE + +SP PP +P G +
Sbjct: 21 RQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPP---------APNGPDKM 71
Query: 356 RQDKPLSPAGS-SQEAADTPDTRHPCSLGSSLVADYSDSES 395
+ + PL P S Q P + P + G+SL + + S
Sbjct: 72 QMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWS 112
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 37.7 bits (86), Expect = 0.018
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 310 AADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQE 369
AA+ P+ +P +D+ +P + E PK S G+ G+R+++P S+E
Sbjct: 838 AAEAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAES--GEPGAREERPRPHRSHSKE 895
Query: 370 AADTPDTR 377
AA P+ R
Sbjct: 896 AAGPPEAR 903
Score = 29.6 bits (65), Expect = 5.0
Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Query: 324 EAAQDRPMSP--GDCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQEAADTP 374
E +D P G PE E P+ P + +DK +PA Q+ A+ P
Sbjct: 820 ELGRDGARGPVGGKARPEAAEAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAP 872
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 37.4 bits (85), Expect = 0.024
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 253 RSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAAD 312
RS+ S S+ + + QSRR+ T +T+ DL + + PES + A
Sbjct: 531 RSYQMPVRDEESESQRKARSRLMRQSRRS---TQGVTLTDLKEAEKAAGKAPESEKPAQS 587
Query: 313 TPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR---GQE--GSRQDKPLSPAGSS 367
S PRVP D P + P P+ + G+E G + + PA S
Sbjct: 588 LDPSRRPRVPGVENSDSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRS 647
Query: 368 QEAA 371
QE++
Sbjct: 648 QESS 651
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 37.4 bits (85), Expect = 0.024
Identities = 66/313 (21%), Positives = 122/313 (38%), Gaps = 41/313 (13%)
Query: 116 QRKEERWDMADNEQVLTT-EHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQS 174
QR+ ER D E+ E E++++ E D + E +R K+ H +
Sbjct: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDRE 473
Query: 175 AWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETED-----DRKLAA 229
++ + + + K ++ Q + + + +A+ T P V ++ R +
Sbjct: 474 KERE--------KEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSP 525
Query: 230 LLKFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPIT 289
K S ++ ++T S S S+ S+ SS SG ++SR ++ ++
Sbjct: 526 KKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSR 585
Query: 290 VG---DLGIVRRRSRDVPESPQ-------HAADTPKSGEPRVPEEAAQDRPM---SPGDC 336
R RSR SP H GEP P A ++ + +P
Sbjct: 586 SSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPA 645
Query: 337 PPETTET----PKCSSPRG-QEGSRQDKP---------LSPAGSSQEAADTPDTRHPCSL 382
PP+ T+T P+ + P +E R+++P LS +GS ++ + + SL
Sbjct: 646 PPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSL 705
Query: 383 GSSLVADYSDSES 395
S V+ S + S
Sbjct: 706 SVSSVSSVSSATS 718
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 37.0 bits (84), Expect = 0.031
Identities = 55/275 (20%), Positives = 101/275 (36%), Gaps = 26/275 (9%)
Query: 116 QRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSA 175
+R+ ER + E+ E E++++ E D E E D +K L + A
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQE 459
Query: 176 WKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDR------KLAA 229
++ + R++ RE +K + EEER + + +A + + +DDR + +A
Sbjct: 460 RLKNWEIRE--RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSA 517
Query: 230 LLK-----FHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALA 284
L K +++ E +K ++ E+ A G +++ A+ RR
Sbjct: 518 LQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ- 576
Query: 285 TSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETP 344
+++ E + K EP EE + +P P + P
Sbjct: 577 -----------IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRP-ISSAP 624
Query: 345 KCSSPRGQEGSRQDKPLSPAGSSQEAADTPDTRHP 379
SS G SP G ++PD + P
Sbjct: 625 SVSSASGNATPNTPGDESPCGIIIPHENSPDQQQP 659
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 37.0 bits (84), Expect = 0.031
Identities = 62/287 (21%), Positives = 102/287 (35%), Gaps = 47/287 (16%)
Query: 93 LCVNYIE---------MQTDPANCDYVIVSGAQRKEERWDMADNEQVLTTEHEKKQKLET 143
LC+ Y+E + DP++ S + ER D A + + TE ++ E
Sbjct: 662 LCLCYLEPKAASLSASLDNDPSDS-----SEEETDSERTDTAADGETTATESDQ----EE 712
Query: 144 DAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDFALNSMLRRRFREKKKAIQEEEER 203
DA + + E + L K +S ++ D A+ + E +K + R
Sbjct: 713 DAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTN-------EWEKRLSTSPVR 765
Query: 204 DQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQKLKRTEIISRSWFPSAPGSA 263
A Q A + PLVPE L+ + S + + K TE I G
Sbjct: 766 LAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESAR-KPTEFI---------GGV 815
Query: 264 SSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPE 323
+S+ S V K ++ + + T P +P S + E R
Sbjct: 816 TSTSQSWVQKMETKTESSGIETEPTV-----------HHLPLSTEKVVQETVLVEERRVV 864
Query: 324 EAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQEA 370
A+ D S GD + P + +G+EGS + G + A
Sbjct: 865 HASGDASYSAGD-SGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVA 910
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 36.6 bits (83), Expect = 0.041
Identities = 47/212 (22%), Positives = 88/212 (41%), Gaps = 15/212 (7%)
Query: 186 LRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQKL 245
LRR+ E K + + RD+ K ++ I ++ ++ +K A LL HT+D+ + L
Sbjct: 1273 LRRQETENK--YETDLGRDRKGDDKKNMLIDIMDTSQ--QKSAGLLMVHTVDATKLDNAL 1328
Query: 246 KRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPE 305
+ + ++ P S+ S GV + + + + A P TV IV S +
Sbjct: 1329 QEED--EKAEVEMKPDSSPSEVPEGV-SETEGALQISAAPEPTTVPGRTIVAVGSMEEAV 1385
Query: 306 SPQHAADTPKSGEPRVPEEAAQDRPMSPG-------DCPPETTETPKCSSPRGQEGSRQD 358
P + E+ P+ P D P + + S ++ + D
Sbjct: 1386 ILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRAASVPALSDLVKQ-KKSD 1444
Query: 359 KPLSPAGSSQEAADTPDTRHPCSLGSSLVADY 390
P SP+ +S + ++ D++ P SL + L A +
Sbjct: 1445 TPQSPSLNSSQPTNSADSKKPASLSNCLPASF 1476
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 36.2 bits (82), Expect = 0.053
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 304 PESPQHAA-DTPKSGEPRVPEEAAQDRPMSPGDCPPETT--ETPKCSSPRGQEGSRQDKP 360
P +P+ AA +TPK P P+E A P P P+ T TPK ++P + P
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591
Query: 361 LSPAGSSQEAADTPDTRHPCS 381
PA +E A T T+ P S
Sbjct: 592 KKPA--PKELAPT-TTKEPTS 609
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 300 SRDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----TTETPKCSSPRGQEG 354
++ P +P+ A T PK P P+E A P P P+ TT+ P ++P+
Sbjct: 291 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHP 379
+ KP +P + A TP P
Sbjct: 351 TAPKKP-APTTPKEPAPTTPKEPAP 374
Score = 33.5 bits (75), Expect = 0.34
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 13/130 (10%)
Query: 257 PSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKS 316
P P ++ K+ A + + T+P + + P+ P A TPK
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEP--APTTPKK 441
Query: 317 GEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR-------GQEGSRQDKPLSPAGSSQE 369
P P+E A P +P + P TT+ P ++P+ + K L+P +
Sbjct: 442 PAPTTPKEPA---PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 370 AADTPDTRHP 379
A TP+ P
Sbjct: 499 APTTPEKPAP 508
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%)
Query: 304 PESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----------TTETPKCSSPRGQ 352
P +P+ A T PK P PE+ A P P PE T TP+ +P
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535
Query: 353 EGSRQDKPLSPAGSS--QEAADTPDTRHP 379
+ + + P PA ++ + A TP P
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 301 RDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDK 359
+ P +P+ A T PK P P+E A P +P P T + P ++P+ + ++
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPK-KPAPKELA 669
Query: 360 PLSPAGSSQEAADTPDTRHP 379
P + G + +D P P
Sbjct: 670 PTTTKGPTSTTSDKPAPTTP 689
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 19/88 (21%)
Query: 310 AADTPKSGEPRVPEEAAQDRPMSPGDCPPETT----------ETPKCSSP--------RG 351
A TPK P P+E A P P P+ T TPK +P +G
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 352 QEGSRQDKPLSPAGSSQEAADTPDTRHP 379
+ DKP +P + A TP P
Sbjct: 676 PTSTTSDKP-APTTPKETAPTTPKEPAP 702
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 216 PLVPETEDDRKLAALL--KFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLK 273
P +P D K +L K T+++ E K+T + SA + S K S K
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA--K 185
Query: 274 KLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSP 333
LA + + +P ++ + P A TPK P P+E A P P
Sbjct: 186 DLAPTSKVLAKPTP-----------KAETTTKGP--ALTTPKEPTPTTPKEPASTTPKEP 232
Query: 334 GDCPPETT-ETPKCSSPRGQEGS-RQDKPLSPAGSSQEAADTPDTRHP 379
++ TPK +P + + K +P + + A TP P
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 306 SPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPET--TETPKCSSP 349
S + A TPK P P+E A P P PET T + S+P
Sbjct: 681 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 726
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 36.2 bits (82), Expect = 0.053
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 304 PESPQHAA-DTPKSGEPRVPEEAAQDRPMSPGDCPPETT--ETPKCSSPRGQEGSRQDKP 360
P +P+ AA +TPK P P+E A P P P+ T TPK ++P + P
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632
Query: 361 LSPAGSSQEAADTPDTRHPCS 381
PA +E A T T+ P S
Sbjct: 633 KKPA--PKELAPT-TTKEPTS 650
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 300 SRDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----TTETPKCSSPRGQEG 354
++ P +P+ A T PK P P+E A P P P+ TT+ P ++P+
Sbjct: 332 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHP 379
+ KP +P + A TP P
Sbjct: 392 TAPKKP-APTTPKEPAPTTPKEPAP 415
Score = 33.5 bits (75), Expect = 0.34
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 13/130 (10%)
Query: 257 PSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKS 316
P P ++ K+ A + + T+P + + P+ P A TPK
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEP--APTTPKK 482
Query: 317 GEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR-------GQEGSRQDKPLSPAGSSQE 369
P P+E A P +P + P TT+ P ++P+ + K L+P +
Sbjct: 483 PAPTTPKEPA---PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 370 AADTPDTRHP 379
A TP+ P
Sbjct: 540 APTTPEKPAP 549
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%)
Query: 304 PESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----------TTETPKCSSPRGQ 352
P +P+ A T PK P PE+ A P P PE T TP+ +P
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576
Query: 353 EGSRQDKPLSPAGSS--QEAADTPDTRHP 379
+ + + P PA ++ + A TP P
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 301 RDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDK 359
+ P +P+ A T PK P P+E A P +P P T + P ++P+ + ++
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPK-KPAPKELA 710
Query: 360 PLSPAGSSQEAADTPDTRHP 379
P + G + +D P P
Sbjct: 711 PTTTKGPTSTTSDKPAPTTP 730
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 19/88 (21%)
Query: 310 AADTPKSGEPRVPEEAAQDRPMSPGDCPPETT----------ETPKCSSP--------RG 351
A TPK P P+E A P P P+ T TPK +P +G
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 352 QEGSRQDKPLSPAGSSQEAADTPDTRHP 379
+ DKP +P + A TP P
Sbjct: 717 PTSTTSDKP-APTTPKETAPTTPKEPAP 743
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 216 PLVPETEDDRKLAALL--KFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLK 273
P +P D K +L K T+++ E K+T + SA + S K S K
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA--K 226
Query: 274 KLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSP 333
LA + + +P ++ + P A TPK P P+E A P P
Sbjct: 227 DLAPTSKVLAKPTP-----------KAETTTKGP--ALTTPKEPTPTTPKEPASTTPKEP 273
Query: 334 GDCPPETT-ETPKCSSPRGQEGS-RQDKPLSPAGSSQEAADTPDTRHP 379
++ TPK +P + + K +P + + A TP P
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 306 SPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPET--TETPKCSSP 349
S + A TPK P P+E A P P PET T + S+P
Sbjct: 722 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 767
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 36.2 bits (82), Expect = 0.053
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 304 PESPQHAA-DTPKSGEPRVPEEAAQDRPMSPGDCPPETT--ETPKCSSPRGQEGSRQDKP 360
P +P+ AA +TPK P P+E A P P P+ T TPK ++P + P
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684
Query: 361 LSPAGSSQEAADTPDTRHPCS 381
PA +E A T T+ P S
Sbjct: 685 KKPA--PKELAPT-TTKEPTS 702
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 300 SRDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----TTETPKCSSPRGQEG 354
++ P +P+ A T PK P P+E A P P P+ TT+ P ++P+
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 443
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHP 379
+ KP +P + A TP P
Sbjct: 444 TAPKKP-APTTPKEPAPTTPKEPAP 467
Score = 33.5 bits (75), Expect = 0.34
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 13/130 (10%)
Query: 257 PSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKS 316
P P ++ K+ A + + T+P + + P+ P A TPK
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEP--APTTPKK 534
Query: 317 GEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR-------GQEGSRQDKPLSPAGSSQE 369
P P+E A P +P + P TT+ P ++P+ + K L+P +
Sbjct: 535 PAPTTPKEPA---PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 370 AADTPDTRHP 379
A TP+ P
Sbjct: 592 APTTPEKPAP 601
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%)
Query: 304 PESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----------TTETPKCSSPRGQ 352
P +P+ A T PK P PE+ A P P PE T TP+ +P
Sbjct: 569 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 628
Query: 353 EGSRQDKPLSPAGSS--QEAADTPDTRHP 379
+ + + P PA ++ + A TP P
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 301 RDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDK 359
+ P +P+ A T PK P P+E A P +P P T + P ++P+ + ++
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPK-KPAPKELA 762
Query: 360 PLSPAGSSQEAADTPDTRHP 379
P + G + +D P P
Sbjct: 763 PTTTKGPTSTTSDKPAPTTP 782
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 19/88 (21%)
Query: 310 AADTPKSGEPRVPEEAAQDRPMSPGDCPPETT----------ETPKCSSP--------RG 351
A TPK P P+E A P P P+ T TPK +P +G
Sbjct: 709 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 768
Query: 352 QEGSRQDKPLSPAGSSQEAADTPDTRHP 379
+ DKP +P + A TP P
Sbjct: 769 PTSTTSDKP-APTTPKETAPTTPKEPAP 795
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 216 PLVPETEDDRKLAALL--KFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLK 273
P +P D K +L K T+++ E K+T + SA + S K S K
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA--K 278
Query: 274 KLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSP 333
LA + + +P ++ + P A TPK P P+E A P P
Sbjct: 279 DLAPTSKVLAKPTP-----------KAETTTKGP--ALTTPKEPTPTTPKEPASTTPKEP 325
Query: 334 GDCPPETT-ETPKCSSPRGQEGS-RQDKPLSPAGSSQEAADTPDTRHP 379
++ TPK +P + + K +P + + A TP P
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 306 SPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPET--TETPKCSSP 349
S + A TPK P P+E A P P PET T + S+P
Sbjct: 774 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 36.2 bits (82), Expect = 0.053
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 304 PESPQHAA-DTPKSGEPRVPEEAAQDRPMSPGDCPPETT--ETPKCSSPRGQEGSRQDKP 360
P +P+ AA +TPK P P+E A P P P+ T TPK ++P + P
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725
Query: 361 LSPAGSSQEAADTPDTRHPCS 381
PA +E A T T+ P S
Sbjct: 726 KKPA--PKELAPT-TTKEPTS 743
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 300 SRDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----TTETPKCSSPRGQEG 354
++ P +P+ A T PK P P+E A P P P+ TT+ P ++P+
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 484
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHP 379
+ KP +P + A TP P
Sbjct: 485 TAPKKP-APTTPKEPAPTTPKEPAP 508
Score = 33.5 bits (75), Expect = 0.34
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 13/130 (10%)
Query: 257 PSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKS 316
P P ++ K+ A + + T+P + + P+ P A TPK
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEP--APTTPKK 575
Query: 317 GEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPR-------GQEGSRQDKPLSPAGSSQE 369
P P+E A P +P + P TT+ P ++P+ + K L+P +
Sbjct: 576 PAPTTPKEPA---PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 370 AADTPDTRHP 379
A TP+ P
Sbjct: 633 APTTPEKPAP 642
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%)
Query: 304 PESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPE----------TTETPKCSSPRGQ 352
P +P+ A T PK P PE+ A P P PE T TP+ +P
Sbjct: 610 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 669
Query: 353 EGSRQDKPLSPAGSS--QEAADTPDTRHP 379
+ + + P PA ++ + A TP P
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 301 RDVPESPQHAADT-PKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDK 359
+ P +P+ A T PK P P+E A P +P P T + P ++P+ + ++
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPA---PTTPKGTAPTTLKEPAPTTPK-KPAPKELA 803
Query: 360 PLSPAGSSQEAADTPDTRHP 379
P + G + +D P P
Sbjct: 804 PTTTKGPTSTTSDKPAPTTP 823
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 19/88 (21%)
Query: 310 AADTPKSGEPRVPEEAAQDRPMSPGDCPPETT----------ETPKCSSP--------RG 351
A TPK P P+E A P P P+ T TPK +P +G
Sbjct: 750 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 809
Query: 352 QEGSRQDKPLSPAGSSQEAADTPDTRHP 379
+ DKP +P + A TP P
Sbjct: 810 PTSTTSDKP-APTTPKETAPTTPKEPAP 836
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 216 PLVPETEDDRKLAALL--KFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLK 273
P +P D K +L K T+++ E K+T + SA + S K S K
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA--K 319
Query: 274 KLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSP 333
LA + + +P ++ + P A TPK P P+E A P P
Sbjct: 320 DLAPTSKVLAKPTP-----------KAETTTKGP--ALTTPKEPTPTTPKEPASTTPKEP 366
Query: 334 GDCPPETT-ETPKCSSPRGQEGS-RQDKPLSPAGSSQEAADTPDTRHP 379
++ TPK +P + + K +P + + A TP P
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 306 SPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPET--TETPKCSSP 349
S + A TPK P P+E A P P PET T + S+P
Sbjct: 815 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 860
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 36.2 bits (82), Expect = 0.053
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 15/178 (8%)
Query: 198 QEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLD----SYEDKQKLKRTEIISR 253
+E+E+R++A+ T E E+ + + D S D + + S
Sbjct: 985 EEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSS 1044
Query: 254 SWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADT 313
S S+ S+SSS S + + R AL ++ ++ + +VP P+ A +
Sbjct: 1045 SSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPV-PERVAGS 1103
Query: 314 PKSGEPRVPEEAAQDRPMSPGD--------CPPETTETPKCSSPRGQEGSRQDKPLSP 363
P + P +EA+ RP P + PPE P +PR E PL P
Sbjct: 1104 PVTPLPE--QEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLP 1159
Score = 29.6 bits (65), Expect = 5.0
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 14/104 (13%)
Query: 297 RRRSRDVPESPQHAADT----PKSGEPRVPEEAAQD-----RPMSPGDCPPETTETPKCS 347
RR +R+ P A +T P S +P E ++ RP + PPE E
Sbjct: 385 RRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGG 444
Query: 348 -----SPRGQEGSRQDKPLSPAGSSQEAADTPDTRHPCSLGSSL 386
SP +E +P SPA S A +T + P + SSL
Sbjct: 445 GGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSL 488
>gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo
sapiens]
Length = 805
Score = 36.2 bits (82), Expect = 0.053
Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 38/181 (20%)
Query: 182 LNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYED 241
L + RR REK+K+ Q +T+P+ + L A ++F +S
Sbjct: 653 LRDSITRRQREKQKS---------GKQTDLEITVPI----RHSQHLPAKVEFGVYESGPR 699
Query: 242 KQKLK-RTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLG------ 294
K + RTE+ W + S +SS + S R+ L+ S GD
Sbjct: 700 KSVIPPRTELRRGDWKTDSTSSTASSTSN------RSSTRSLLSVSSGMEGDNEDNEVPE 753
Query: 295 IVRRRSRDVPE---SPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRG 351
+ R RS P+ +P + + P PRVP AA RP + ET P PRG
Sbjct: 754 VTRSRSPGPPQVDGTPTMSLERP----PRVPPRAASQRPPT-----RETFHPPPPVPPRG 804
Query: 352 Q 352
+
Sbjct: 805 R 805
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 35.8 bits (81), Expect = 0.069
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 24/161 (14%)
Query: 128 EQVLTTEHEKKQKLETDAMFRLEH---GEADRSTLKKALPTLSHIQEAQSAWKDDFALNS 184
E L+T + + ETD+ + + G + KK L +QEA+ W+ AL
Sbjct: 576 ESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLL-MFKRVQEAEDKWRGAQALIE 634
Query: 185 MLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQK 244
++ F EK+K ++ + E + Q K L +D+ L A L S+E+ K
Sbjct: 635 QIKATFSEKEKELENKLEELKKQQEK-----ELFKLNQDNYILQA-----KLSSFEETNK 684
Query: 245 LKRTEIISRSW--FPSAPGSASSSKVSGVLKKLAQSRRTAL 283
+R W F A + K+ + K++ Q + T L
Sbjct: 685 KQR-------WLHFGEAADPVTGEKLKQIQKEI-QEQETLL 717
>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
sapiens]
Length = 355
Score = 35.4 bits (80), Expect = 0.091
Identities = 44/146 (30%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 254 SWFPSAPGSASSSKVSGVLKK---LAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHA 310
S +PS PG A S K L QS++ A T+G G R SP H
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKA---DTETIGSSGGSRG------PSPAHP 80
Query: 311 ADTPKSGEPRVP--EEAAQDRPMSPGDCPPET-TETPKCSSP---RGQEGSRQDKPLSPA 364
TP+ G P P A+ R P D P+ T P+ S P G SR L+
Sbjct: 81 WTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKY 140
Query: 365 GSSQEAADTPDTRHP-------CSLG 383
S+ ++ P R P C LG
Sbjct: 141 NSAHSSSRVPRPRLPSQRRGASCGLG 166
>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
sapiens]
Length = 355
Score = 35.4 bits (80), Expect = 0.091
Identities = 44/146 (30%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 254 SWFPSAPGSASSSKVSGVLKK---LAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHA 310
S +PS PG A S K L QS++ A T+G G R SP H
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKA---DTETIGSSGGSRG------PSPAHP 80
Query: 311 ADTPKSGEPRVP--EEAAQDRPMSPGDCPPET-TETPKCSSP---RGQEGSRQDKPLSPA 364
TP+ G P P A+ R P D P+ T P+ S P G SR L+
Sbjct: 81 WTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKY 140
Query: 365 GSSQEAADTPDTRHP-------CSLG 383
S+ ++ P R P C LG
Sbjct: 141 NSAHSSSRVPRPRLPSQRRGASCGLG 166
>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
sapiens]
Length = 355
Score = 35.4 bits (80), Expect = 0.091
Identities = 44/146 (30%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 254 SWFPSAPGSASSSKVSGVLKK---LAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHA 310
S +PS PG A S K L QS++ A T+G G R SP H
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKA---DTETIGSSGGSRG------PSPAHP 80
Query: 311 ADTPKSGEPRVP--EEAAQDRPMSPGDCPPET-TETPKCSSP---RGQEGSRQDKPLSPA 364
TP+ G P P A+ R P D P+ T P+ S P G SR L+
Sbjct: 81 WTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKY 140
Query: 365 GSSQEAADTPDTRHP-------CSLG 383
S+ ++ P R P C LG
Sbjct: 141 NSAHSSSRVPRPRLPSQRRGASCGLG 166
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 35.4 bits (80), Expect = 0.091
Identities = 51/224 (22%), Positives = 86/224 (38%), Gaps = 21/224 (9%)
Query: 128 EQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDFALNSMLR 187
E+ ++ EK Q E +AM ++ E K L + I +KD LR
Sbjct: 399 EENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREI------YKDANTQVHTLR 452
Query: 188 RRFREKKKAIQEEEERDQAL-QAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQKLK 246
+ +EK++AIQ + ++ + + + TI + + + D + ++ TL
Sbjct: 453 KMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLS--------M 504
Query: 247 RTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPES 306
+E+++ + G+ASS + L S T P TV + + P
Sbjct: 505 GSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDT-----PETVQNGPVTPPMPPPPPPP 559
Query: 307 PQHAADTPKSGEPRVPEEAAQDRPMSPGDCP-PETTETPKCSSP 349
P P P +P AA+ P P P P P SSP
Sbjct: 560 PPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSP 603
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 35.4 bits (80), Expect = 0.091
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA Q + P ET + K P+ E
Sbjct: 240 IQPKEGDIPKSPEEAIQ-PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEE 298
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSL 386
+ Q K S ++A + P SL ++
Sbjct: 299 AIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAI 330
Score = 34.7 bits (78), Expect = 0.15
Identities = 20/87 (22%), Positives = 36/87 (41%)
Query: 296 VRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGS 355
++ + D+P+SP+ K P+ PEEA Q + P + + + P+ E +
Sbjct: 270 IQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEA 329
Query: 356 RQDKPLSPAGSSQEAADTPDTRHPCSL 382
K + S +E + P SL
Sbjct: 330 IPPKEIDIPKSPEETIQPKEDDSPKSL 356
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA + + P ET + + SP+ E
Sbjct: 300 IQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEE 358
Query: 355 SRQDKPLSPAGSSQEAADTPD 375
+ K +E + P+
Sbjct: 359 ATPSKEGDILKPEEETMEFPE 379
Score = 28.9 bits (63), Expect = 8.5
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+S + A PK G+ P+ PEE Q + P E + + P+ +
Sbjct: 255 IQPKEGDIPKSLEEAIQ-PKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 313
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSLVADYSDS 393
+ Q K S +EA + P S ++ DS
Sbjct: 314 AIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDS 352
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 35.4 bits (80), Expect = 0.091
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA Q + P ET + K P+ E
Sbjct: 307 IQPKEGDIPKSPEEAIQ-PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEE 365
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSL 386
+ Q K S ++A + P SL ++
Sbjct: 366 AIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAI 397
Score = 34.7 bits (78), Expect = 0.15
Identities = 20/87 (22%), Positives = 36/87 (41%)
Query: 296 VRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGS 355
++ + D+P+SP+ K P+ PEEA Q + P + + + P+ E +
Sbjct: 337 IQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEA 396
Query: 356 RQDKPLSPAGSSQEAADTPDTRHPCSL 382
K + S +E + P SL
Sbjct: 397 IPPKEIDIPKSPEETIQPKEDDSPKSL 423
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA + + P ET + + SP+ E
Sbjct: 367 IQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEE 425
Query: 355 SRQDKPLSPAGSSQEAADTPD 375
+ K +E + P+
Sbjct: 426 ATPSKEGDILKPEEETMEFPE 446
Score = 28.9 bits (63), Expect = 8.5
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+S + A PK G+ P+ PEE Q + P E + + P+ +
Sbjct: 322 IQPKEGDIPKSLEEAIQ-PKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 380
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSLVADYSDS 393
+ Q K S +EA + P S ++ DS
Sbjct: 381 AIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDS 419
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 35.4 bits (80), Expect = 0.091
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA Q + P ET + K P+ E
Sbjct: 240 IQPKEGDIPKSPEEAIQ-PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEE 298
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSL 386
+ Q K S ++A + P SL ++
Sbjct: 299 AIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAI 330
Score = 34.7 bits (78), Expect = 0.15
Identities = 20/87 (22%), Positives = 36/87 (41%)
Query: 296 VRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGS 355
++ + D+P+SP+ K P+ PEEA Q + P + + + P+ E +
Sbjct: 270 IQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEA 329
Query: 356 RQDKPLSPAGSSQEAADTPDTRHPCSL 382
K + S +E + P SL
Sbjct: 330 IPPKEIDIPKSPEETIQPKEDDSPKSL 356
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+SP+ A PK G+ P+ EEA + + P ET + + SP+ E
Sbjct: 300 IQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEE 358
Query: 355 SRQDKPLSPAGSSQEAADTPD 375
+ K +E + P+
Sbjct: 359 ATPSKEGDILKPEEETMEFPE 379
Score = 28.9 bits (63), Expect = 8.5
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Query: 296 VRRRSRDVPESPQHAADTPKSGE-PRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEG 354
++ + D+P+S + A PK G+ P+ PEE Q + P E + + P+ +
Sbjct: 255 IQPKEGDIPKSLEEAIQ-PKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 313
Query: 355 SRQDKPLSPAGSSQEAADTPDTRHPCSLGSSLVADYSDS 393
+ Q K S +EA + P S ++ DS
Sbjct: 314 AIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDS 352
>gi|154800453 tastin isoform 1 [Homo sapiens]
Length = 778
Score = 35.4 bits (80), Expect = 0.091
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 12/86 (13%)
Query: 302 DVPESPQHAADTPKSG----EPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQ 357
+VPE A P EP +PE + Q++ P CPP + PR E +
Sbjct: 543 EVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPP--------AEPRPLESYCR 594
Query: 358 DKPLSPAGSSQEAADTPDTRHPCSLG 383
+P P S QE + P+ P G
Sbjct: 595 IEPEIPESSRQEQLEVPEPCPPAEPG 620
Score = 30.8 bits (68), Expect = 2.2
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 11/63 (17%)
Query: 318 EPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQEAADTPDTR 377
EP +PE + Q++ P PP + PR E + +P P S QE + P+
Sbjct: 530 EPEIPEPSLQEQLEVPEPYPP--------AEPRPLESCCRSEPEIPESSRQEQLEVPE-- 579
Query: 378 HPC 380
PC
Sbjct: 580 -PC 581
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,929,898
Number of Sequences: 37866
Number of extensions: 846977
Number of successful extensions: 4877
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 305
Number of HSP's that attempted gapping in prelim test: 4308
Number of HSP's gapped (non-prelim): 771
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.