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Search of human proteins with 57863301
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57863301 CLIP-associating protein 2 [Homo sapiens]
(1506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57863301 CLIP-associating protein 2 [Homo sapiens] 2938 0.0
gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens] 1982 0.0
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens] 1920 0.0
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens] 1912 0.0
gi|93102424 hypothetical protein LOC23116 [Homo sapiens] 61 7e-09
gi|57222563 colonic and hepatic tumor over-expressed protein iso... 58 8e-08
gi|57164942 colonic and hepatic tumor over-expressed protein iso... 58 8e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 51 1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 49 3e-05
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 48 8e-05
gi|60097902 filaggrin [Homo sapiens] 46 2e-04
gi|161016767 mucin 21 [Homo sapiens] 46 2e-04
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 45 7e-04
gi|8923040 CDKN2A interacting protein [Homo sapiens] 45 7e-04
gi|88758580 cyclin L2 isoform A [Homo sapiens] 44 0.002
gi|21361794 TIP120 protein [Homo sapiens] 44 0.002
gi|57864582 hornerin [Homo sapiens] 43 0.003
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 42 0.003
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 42 0.006
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 42 0.006
gi|193083131 MAP/microtubule affinity-regulating kinase 3 isofor... 42 0.006
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor... 42 0.006
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor... 42 0.006
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform... 42 0.006
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 40 0.013
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 40 0.017
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 40 0.017
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 40 0.017
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 40 0.017
>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
Length = 1506
Score = 2938 bits (7617), Expect = 0.0
Identities = 1506/1506 (100%), Positives = 1506/1506 (100%)
Query: 1 MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVG 60
MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVG
Sbjct: 1 MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVG 60
Query: 61 SSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMD 120
SSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMD
Sbjct: 61 SSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMD 120
Query: 121 QVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSN 180
QVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSN
Sbjct: 121 QVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSN 180
Query: 181 SQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKDK 240
SQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKDK
Sbjct: 181 SQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKDK 240
Query: 241 SFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGPKVGGASKEGGAGAVDE 300
SFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGPKVGGASKEGGAGAVDE
Sbjct: 241 SFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGPKVGGASKEGGAGAVDE 300
Query: 301 DDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQY 360
DDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQY
Sbjct: 301 DDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQY 360
Query: 361 DCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVP 420
DCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVP
Sbjct: 361 DCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVP 420
Query: 421 NSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHS 480
NSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHS
Sbjct: 421 NSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHS 480
Query: 481 LERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTY 540
LERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTY
Sbjct: 481 LERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTY 540
Query: 541 LKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQR 600
LKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQR
Sbjct: 541 LKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQR 600
Query: 601 SRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRA 660
SRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRA
Sbjct: 601 SRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRA 660
Query: 661 KLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNS 720
KLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNS
Sbjct: 661 KLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNS 720
Query: 721 ASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQ 780
ASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQ
Sbjct: 721 ASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQ 780
Query: 781 PLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSD 840
PLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSD
Sbjct: 781 PLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSD 840
Query: 841 ASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLS 900
ASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLS
Sbjct: 841 ASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLS 900
Query: 901 RVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGAD 960
RVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGAD
Sbjct: 901 RVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGAD 960
Query: 961 LLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMD 1020
LLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMD
Sbjct: 961 LLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMD 1020
Query: 1021 PGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQ 1080
PGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQ
Sbjct: 1021 PGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQ 1080
Query: 1081 DGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYD 1140
DGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYD
Sbjct: 1081 DGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYD 1140
Query: 1141 TENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGG 1200
TENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGG
Sbjct: 1141 TENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGG 1200
Query: 1201 DATDSSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQF 1260
DATDSSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQF
Sbjct: 1201 DATDSSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQF 1260
Query: 1261 PDDLSLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLL 1320
PDDLSLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLL
Sbjct: 1261 PDDLSLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLL 1320
Query: 1321 ETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAAS 1380
ETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAAS
Sbjct: 1321 ETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAAS 1380
Query: 1381 VLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQG 1440
VLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQG
Sbjct: 1381 VLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQG 1440
Query: 1441 YDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTT 1500
YDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTT
Sbjct: 1441 YDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTT 1500
Query: 1501 DVSGQS 1506
DVSGQS
Sbjct: 1501 DVSGQS 1506
>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
Length = 1538
Score = 1982 bits (5135), Expect = 0.0
Identities = 1058/1562 (67%), Positives = 1231/1562 (78%), Gaps = 80/1562 (5%)
Query: 1 MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDAL-TGWV 59
MEPR ME AQV QKDVG RLQVGQEL+ Y +DLE D L K VD L T WV
Sbjct: 1 MEPR-MESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWV 59
Query: 60 GSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLM 119
SSNY+V L+G++ILSA V RL RFK+ + V+ +LIDR+GDAKD VR++ QTL+LK+M
Sbjct: 60 NSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIM 119
Query: 120 DQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDS 179
DQ A P Y+W+++ GFKHKNFR+REG+CLCLI TLN GAQ L +SK++PH+C L GD
Sbjct: 120 DQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDP 179
Query: 180 NSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKD 239
NSQVRDAAI ++VEIYRHVGE+VR DL K+G+P +RL +IF KFDEVQ SG MI S D
Sbjct: 180 NSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSA-ND 238
Query: 240 KSFDDEESVDGNRPSSAASAFKVPAPKTSGNPA-NSARKPGSAGGPKVGGASKEGGAGAV 298
K+FDDE+SVDGNRPSSA+S P + N + R+ GS+ A+KEG AGAV
Sbjct: 239 KNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEG-AGAV 297
Query: 299 DEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAA 358
DE+DFIKAF DVP +QIYSSR+LEE++NKIREILSDDKHDW+QR NALKKIRSLL+AGAA
Sbjct: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
Query: 359 QYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNL 418
+YD FFQHLRLLDGA KLSAKDLRSQVVREACIT+ HLS+VLGNKFDHGAEAI+PT+FNL
Sbjct: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
Query: 419 VPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQT 478
+PNSAK+MATSG A+R IIRHTH+PRLIP+ITSNCTSKSV VRRR FEFLDLLLQEWQT
Sbjct: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQT 477
Query: 479 HSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQ 538
HSLERH +VL ETIKKGIHDAD+EAR+EARK Y G +HF EAE LY++LE SYQK+LQ
Sbjct: 478 HSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
Query: 539 TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL 598
++LK+S S+ SLPQSDRSSSSSQESLNRP S+K S +T R S S+K+ S GSL
Sbjct: 538 SHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTT--SRASTVSTKSVSTTGSL 595
Query: 599 QRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658
QRSRSDIDVNAAA AK+ + S + A AL GSYASL GR+
Sbjct: 596 QRSRSDIDVNAAASAKSK-VSSSSGTTPFSSAAALPPGSYASL--------------GRI 640
Query: 659 RAKLSAPLAGMGNAKA-DSRGRSRTKMVSQSQ---------PGSRSGSPGRVLTTTALST 708
R + + + A D+RGRSR K+VSQSQ GSRS SPG++L +
Sbjct: 641 RTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGS-GYGG 699
Query: 709 VSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRE 768
++ G R + S++KRSKIPRSQGCSRE SP+R+ +ARSSRIPRPS+SQGCSR+ SRE
Sbjct: 700 LTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRE 759
Query: 769 SSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYES 828
SSRDTSP R F PL +G+ Q R+ SV+AMRVL+T +D+E AVADALKKP RRRYE
Sbjct: 760 SSRDTSPARGFPPLDR-FGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEP 818
Query: 829 YGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLG 888
YGM+SDDDANSDASS CSERSY SRNG IP Y+RQTEDVAEVLN CASSNWSERKEGLLG
Sbjct: 819 YGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLG 878
Query: 889 LQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFV 948
LQNLLK+QRTLSRVELKRLCEIFTRMFADPH KRVFSMFLETLVDFI +HKDDLQDWLFV
Sbjct: 879 LQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFV 938
Query: 949 LLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAI 1008
LLTQLLKKMGADLLGSVQAKVQKALDVTR+SFP D QFNILMRF VDQTQTP+LKVKVAI
Sbjct: 939 LLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAI 998
Query: 1009 LKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEF 1068
LKYIE+LA+QMDP DF+NSSETRLAVSR+ITWTTEPKSSDVRKAAQ VLISLFELNTPEF
Sbjct: 999 LKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEF 1058
Query: 1069 TMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTS 1128
TMLLGALPKTFQDGATKLLHNHL+N+ N + S + + R R ++ +SPLTSPTN S
Sbjct: 1059 TMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCS 1118
Query: 1129 QNTLSPSAF---------------------------------------DYDTENMNSEDI 1149
LSPS DYDTEN+NSE+I
Sbjct: 1119 HGGLSPSRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEI 1178
Query: 1150 YSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRA---GGDATDSS 1206
YSSLRGVTEAI+ FSFRSQED+NEP+KRD KK+ D + G + P GG +
Sbjct: 1179 YSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKEC-DIVSRDGGAASPATEGRGGSEVEGG 1237
Query: 1207 QTALDNKASLLHSMPTHS--SPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDL 1264
+TALDNK SLL++ P + PR+RDYNPY YSD+I+ ++K+ALKEA+FDDD +Q D +
Sbjct: 1238 RTALDNKTSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRD-V 1296
Query: 1265 SLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLG 1324
+DHSDLVA+LLKELSNHNERVEERK AL EL+K+T+E+S VW+EHFKTILLLLLETLG
Sbjct: 1297 PIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLG 1356
Query: 1325 DKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAASVLAT 1384
DK+ +IRALAL+VLREILR+QPARFKNYAELT+MKTLEAHKD HKEVVR+AEEAAS LA+
Sbjct: 1357 DKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLAS 1416
Query: 1385 SISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQGYDNS 1444
SI PEQCIKVLCPIIQTADYPINLAAIKMQTKV+ER++KE+L LL +I+PGL+QGYDN+
Sbjct: 1417 SIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNT 1476
Query: 1445 ESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTTDVSG 1504
ESSVRKA VFCLVA+++VIG++LKPHL+QLTGSKMKLLNLYIKRAQT + + ++DVS
Sbjct: 1477 ESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVST 1536
Query: 1505 QS 1506
S
Sbjct: 1537 HS 1538
>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
Length = 1479
Score = 1920 bits (4975), Expect = 0.0
Identities = 1031/1531 (67%), Positives = 1203/1531 (78%), Gaps = 77/1531 (5%)
Query: 1 MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDAL-TGWV 59
MEPR ME AQV QKDVG RLQVGQEL+ Y +DLE D L K VD L T WV
Sbjct: 1 MEPR-MESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWV 59
Query: 60 GSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLM 119
SSNY+V L+G++ILSA V RL RFK+ + V+ +LIDR+GDAKD VR++ QTL+LK+M
Sbjct: 60 NSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIM 119
Query: 120 DQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDS 179
DQ A P Y+W+++ GFKHKNFR+REG+CLCLI TLN GAQ L +SK++PH+C L GD
Sbjct: 120 DQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDP 179
Query: 180 NSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKD 239
NSQVRDAAI ++VEIYRHVGE+VR DL K+G+P +RL +IF KFDEVQ SG MI S D
Sbjct: 180 NSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSA-ND 238
Query: 240 KSFDDEESVDGNRPSSAASAFKVPAPKTSGNPA-NSARKPGSAGGPKVGGASKEGGAGAV 298
K+FDDE+SVDGNRPSSA+S P + N + R+ GS+ A+KEG AGAV
Sbjct: 239 KNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEG-AGAV 297
Query: 299 DEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAA 358
DE+DFIKAF DVP +QIYSSR+LEE++NKIREILSDDKHDW+QR NALKKIRSLL+AGAA
Sbjct: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
Query: 359 QYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNL 418
+YD FFQHLRLLDGA KLSAKDLRSQVVREACIT+ HLS+VLGNKFDHGAEAI+PT+FNL
Sbjct: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
Query: 419 VPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQT 478
+PNSAK+MATSG A+R IIRHTH+PRLIP+ITSNCTSKSV VRRR FEFLDLLLQEWQT
Sbjct: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQT 477
Query: 479 HSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQ 538
HSLERH +VL ETIKKGIHDAD+EAR+EARK Y G +HF EAE LY++LE SYQK+LQ
Sbjct: 478 HSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
Query: 539 TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL 598
++LK+S S+ SLPQSDRSSSSSQESLNRP S+K S +T R S S+K+ S GSL
Sbjct: 538 SHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTT--SRASTVSTKSVSTTGSL 595
Query: 599 QRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658
QRSRSDIDVNAAA AK+ + S + A AL GSYASL+ T+ K +G R
Sbjct: 596 QRSRSDIDVNAAASAKSK-VSSSSGTTPFSSAAALPPGSYASLDGTTTKAEGRI----RT 650
Query: 659 RAKLSAPLAGMGNAKADSRGRSRTKMVSQSQ---------PGSRSGSPGRVLTTTALSTV 709
R + S + + D+RGRSR K+VSQSQ GSRS SPG++L + +
Sbjct: 651 RRQSSGSATNVASTP-DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGS-GYGGL 708
Query: 710 SSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRES 769
+ G R + S++KRSKIPRSQGC
Sbjct: 709 TGGSSRGPPVTPSSEKRSKIPRSQGC---------------------------------- 734
Query: 770 SRDTSPVRSFQPLG-PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADAL--------KK 820
SR+TSP R +G +G+ Q R+ SV+AMRVL+T +D+E AVADAL KK
Sbjct: 735 SRETSPNR----IGLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKKK 790
Query: 821 PARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWS 880
P RRRYE YGM+SDDDANSDASS CSERSY SRNG IP Y+RQTEDVAEVLN CASSNWS
Sbjct: 791 PVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWS 850
Query: 881 ERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKD 940
ERKEGLLGLQNLLK+QRTLSRVELKRLCEIFTRMFADPH KRVFSMFLETLVDFI +HKD
Sbjct: 851 ERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKD 910
Query: 941 DLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTP 1000
DLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTR+SFP D QFNILMRF VDQTQTP
Sbjct: 911 DLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTP 970
Query: 1001 SLKVKVAILKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISL 1060
+LKVKVAILKYIE+LA+QMDP DF+NSSETRLAVSR+ITWTTEPKSSDVRKAAQ VLISL
Sbjct: 971 NLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISL 1030
Query: 1061 FELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSP 1120
FELNTPEFTMLLGALPKTFQDGATKLLHNHL+N+ N + S + + R R ++ +SP
Sbjct: 1031 FELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSP 1090
Query: 1121 LTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSK 1180
LTSPTN S LSPS DYDTEN+NSE+IYSSLRGVTEAI+ FSFRSQED+NEP+KRD K
Sbjct: 1091 LTSPTNCSHGGLSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGK 1150
Query: 1181 KDDGDSMCGGPGMSDPRA---GGDATDSSQTALDNKASLLHSMPTHS--SPRSRDYNPYN 1235
K + D + G + P GG + +TALDNK SLL++ P + PR+RDYNPY
Sbjct: 1151 K-ECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPRARDYNPYP 1209
Query: 1236 YSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSDLVAELLKELSNHNERVEERKIALYE 1295
YSD+I+ ++K+ALKEA+FDDD +Q D+ +DHSDLVA+LLKELSNHNERVEERK AL E
Sbjct: 1210 YSDAINTYDKTALKEAVFDDDMEQL-RDVPIDHSDLVADLLKELSNHNERVEERKGALLE 1268
Query: 1296 LMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAEL 1355
L+K+T+E+S VW+EHFKTILLLLLETLGDK+ +IRALAL+VLREILR+QPARFKNYAEL
Sbjct: 1269 LLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAEL 1328
Query: 1356 TVMKTLEAHKDPHKEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQT 1415
T+MKTLEAHKD HKEVVR+AEEAAS LA+SI PEQCIKVLCPIIQTADYPINLAAIKMQT
Sbjct: 1329 TIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQT 1388
Query: 1416 KVIERVSKETLNLLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLT 1475
KV+ER++KE+L LL +I+PGL+QGYDN+ESSVRKA VFCLVA+++VIG++LKPHL+QLT
Sbjct: 1389 KVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLT 1448
Query: 1476 GSKMKLLNLYIKRAQTGSGGADPTTDVSGQS 1506
GSKMKLLNLYIKRAQT + + ++DVS S
Sbjct: 1449 GSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1479
>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
Length = 1471
Score = 1912 bits (4954), Expect = 0.0
Identities = 1029/1532 (67%), Positives = 1199/1532 (78%), Gaps = 87/1532 (5%)
Query: 1 MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDAL-TGWV 59
MEPR ME AQV QKDVG RLQVGQEL+ Y +DLE D L K VD L T WV
Sbjct: 1 MEPR-MESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWV 59
Query: 60 GSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLM 119
SSNY+V L+G++ILSA V RL RFK+ + V+ +LIDR+GDAKD VR++ QTL+LK+M
Sbjct: 60 NSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIM 119
Query: 120 DQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDS 179
DQ A P Y+W+++ GFKHKNFR+REG+CLCLI TLN GAQ L +SK++PH+C L GD
Sbjct: 120 DQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDP 179
Query: 180 NSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKD 239
NSQVRDAAI ++VEIYRHVGE+VR DL K+G+P +RL +IF KFDEVQ SG MI S D
Sbjct: 180 NSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSA-ND 238
Query: 240 KSFDDEESVDGNRPSSAASAFKVPAPKTSGNPA-NSARKPGSAGGPKVGGASKEGGAGAV 298
K+FDDE+SVDGNRPSSA+S P + N + R+ GS+ A+KEG AGAV
Sbjct: 239 KNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEG-AGAV 297
Query: 299 DEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAA 358
DE+DFIKAF DVP +QIYSSR+LEE++NKIREILSDDKHDW+QR NALKKIRSLL+AGAA
Sbjct: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
Query: 359 QYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNL 418
+YD FFQHLRLLDGA KLSAKDLRSQVVREACIT+ HLS+VLGNKFDHGAEAI+PT+FNL
Sbjct: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
Query: 419 VPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQT 478
+PNSAK+MATSG A+R IIRHTH+PRLIP+ITSNCTSKSV VRRR FEFLDLLLQEWQT
Sbjct: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQT 477
Query: 479 HSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQ 538
HSLERH +VL ETIKKGIHDAD+EAR+EARK Y G +HF EAE LY++LE SYQK+LQ
Sbjct: 478 HSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
Query: 539 TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL 598
++LK+S S+ SLPQSDRSSSSSQESLNRP S+K S +T R S S+K+ S GSL
Sbjct: 538 SHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTT--SRASTVSTKSVSTTGSL 595
Query: 599 QRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658
QRSRSDIDVNAAA AK+ + S + A AL GSYASL GR+
Sbjct: 596 QRSRSDIDVNAAASAKSK-VSSSSGTTPFSSAAALPPGSYASL--------------GRI 640
Query: 659 RAKLSAPLAGMGNAKA-DSRGRSRTKMVSQSQ---------PGSRSGSPGRVLTTTALST 708
R + + + A D+RGRSR K+VSQSQ GSRS SPG++L +
Sbjct: 641 RTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGS-GYGG 699
Query: 709 VSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRE 768
++ G R + S++KRSKIPRSQGC
Sbjct: 700 LTGGSSRGPPVTPSSEKRSKIPRSQGC--------------------------------- 726
Query: 769 SSRDTSPVRSFQPLG-PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADAL--------K 819
SR+TSP R +G +G+ Q R+ SV+AMRVL+T +D+E AVADAL K
Sbjct: 727 -SRETSPNR----IGLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKK 781
Query: 820 KPARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNW 879
KP RRRYE YGM+SDDDANSDASS CSERSY SRNG IP Y+RQTEDVAEVLN CASSNW
Sbjct: 782 KPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNW 841
Query: 880 SERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHK 939
SERKEGLLGLQNLLK+QRTLSRVELKRLCEIFTRMFADPH KRVFSMFLETLVDFI +HK
Sbjct: 842 SERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHK 901
Query: 940 DDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQT 999
DDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTR+SFP D QFNILMRF VDQTQT
Sbjct: 902 DDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQT 961
Query: 1000 PSLKVKVAILKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLIS 1059
P+LKVKVAILKYIE+LA+QMDP DF+NSSETRLAVSR+ITWTTEPKSSDVRKAAQ VLIS
Sbjct: 962 PNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLIS 1021
Query: 1060 LFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSS 1119
LFELNTPEFTMLLGALPKTFQDGATKLLHNHL+N+ N + S + + R R ++ +S
Sbjct: 1022 LFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTS 1081
Query: 1120 PLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDS 1179
PLTSPTN S LSPS DYDTEN+NSE+IYSSLRGVTEAI+ FSFRSQED+NEP+KRD
Sbjct: 1082 PLTSPTNCSHGGLSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDG 1141
Query: 1180 KKDDGDSMCGGPGMSDPRA---GGDATDSSQTALDNKASLLHSMPTHS--SPRSRDYNPY 1234
KK + D + G + P GG + +TALDNK SLL++ P + PR+RDYNPY
Sbjct: 1142 KK-ECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPRARDYNPY 1200
Query: 1235 NYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSDLVAELLKELSNHNERVEERKIALY 1294
YSD+I+ ++K+ALKEA+FDDD +Q D+ +DHSDLVA+LLKELSNHNERVEERK AL
Sbjct: 1201 PYSDAINTYDKTALKEAVFDDDMEQL-RDVPIDHSDLVADLLKELSNHNERVEERKGALL 1259
Query: 1295 ELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAE 1354
EL+K+T+E+S VW+EHFKTILLLLLETLGDK+ +IRALAL+VLREILR+QPARFKNYAE
Sbjct: 1260 ELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAE 1319
Query: 1355 LTVMKTLEAHKDPHKEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQ 1414
LT+MKTLEAHKD HKEVVR+AEEAAS LA+SI PEQCIKVLCPIIQTADYPINLAAIKMQ
Sbjct: 1320 LTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQ 1379
Query: 1415 TKVIERVSKETLNLLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDELKPHLSQL 1474
TKV+ER++KE+L LL +I+PGL+QGYDN+ESSVRKA VFCLVA+++VIG++LKPHL+QL
Sbjct: 1380 TKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQL 1439
Query: 1475 TGSKMKLLNLYIKRAQTGSGGADPTTDVSGQS 1506
TGSKMKLLNLYIKRAQT + + ++DVS S
Sbjct: 1440 TGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1471
>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
Length = 1720
Score = 61.2 bits (147), Expect = 7e-09
Identities = 55/196 (28%), Positives = 85/196 (43%), Gaps = 4/196 (2%)
Query: 13 VQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLE 72
+ Q+D R Q +EL LG S L + L + SN++V LE
Sbjct: 360 LDQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGF---ISLLYNLLDDSNFKVVHGTLE 416
Query: 73 ILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYIWEQL 132
+L V RL + + ++ VI A + + D K ++ E + LKLM +V P + L
Sbjct: 417 VLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLC-LL 475
Query: 133 ASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIV 192
KHK+ R RE V I +L + ++ + KL L DS +VR AA+ A
Sbjct: 476 LEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFA 535
Query: 193 EIYRHVGEKVRMDLYK 208
+ +G L+K
Sbjct: 536 VLASSMGSGKTSILFK 551
>gi|57222563 colonic and hepatic tumor over-expressed protein
isoform b [Homo sapiens]
Length = 1972
Score = 57.8 bits (138), Expect = 8e-08
Identities = 57/253 (22%), Positives = 110/253 (43%), Gaps = 10/253 (3%)
Query: 57 GWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLIL 116
GW +N++V M L I+ A + + K+ +V+ L+D++GD K + A+ +
Sbjct: 649 GWK-ETNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVK--CGNNAKEAMT 704
Query: 117 KLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILF 176
+ + P + ++ F KN +++ L + FG L + I ++
Sbjct: 705 AIAEACMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTAL 764
Query: 177 GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEV--QSSGGMIL 234
+N VR AAI + +Y +VG +RM + PA L I A+F+++ QS
Sbjct: 765 AATNPAVRTAAITLLGVMYLYVGPSLRM--FFEDEKPALLSQIDAEFEKMQGQSPPAPTR 822
Query: 235 SVCKDKSFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGP--KVGGASKE 292
+ K + +E DG+ P ++ P+T + ++ G K+ +
Sbjct: 823 GISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLD 882
Query: 293 GGAGAVDEDDFIK 305
AG +++ FI+
Sbjct: 883 EVAGIINDAKFIQ 895
Score = 55.8 bits (133), Expect = 3e-07
Identities = 86/372 (23%), Positives = 143/372 (38%), Gaps = 59/372 (15%)
Query: 50 KTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRD 109
K + + +V SN V L GLE +V+ K+ +V + K K ++
Sbjct: 48 KFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKE 107
Query: 110 EAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLI 169
+ L ++ + + E+L G +KN + L + L+ FG++ +++ +I
Sbjct: 108 LGIEICLMYIE-IEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPII 166
Query: 170 PHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSS 229
L LF VRD A L VEIYR + + +R L + I +L+ +
Sbjct: 167 KVLPKLFESREKAVRDEAKLIAVEIYRWIRDALRPPL--QNINSVQLKEL---------- 214
Query: 230 GGMILSVCKDKSFDDEESVDGNRPSSAASAFKVPAP----KTSGNPANSARKPGSAGGPK 285
+EE V P+SA P P ++ + SAGG
Sbjct: 215 --------------EEEWV--KLPTSA------PRPTRFLRSQQELEAKLEQQQSAGGDA 252
Query: 286 VGGASKEGGAGAVDEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSD--DKHDWDQRA 343
GG D+ D +VP I Y E E L+K+ + D + W +R
Sbjct: 253 EGGG---------DDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERK 297
Query: 344 NALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNK 403
AL+ + L+ + + L+ K+ KD +V A + L+ L K
Sbjct: 298 EALESVEVLIKNPKLEAG---DYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKK 354
Query: 404 FDHGAEAIVPTL 415
F A +VPT+
Sbjct: 355 FGQYAGHVVPTI 366
Score = 55.1 bits (131), Expect = 5e-07
Identities = 128/609 (21%), Positives = 222/609 (36%), Gaps = 70/609 (11%)
Query: 36 GAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVA 95
G I+D + +G+ AL G + SN + L IL + K +V + +
Sbjct: 886 GIINDAKFIQPNIGELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIP 945
Query: 96 LIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYI-WEQLASGFKHKNFRSREGVCLCLIET 154
+I +GD+K+ VR A + +Q ++ E L+ K +N R+ + L E
Sbjct: 946 IITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEK 1005
Query: 155 LNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPA 214
L + P + +PHL D N VR A A+ H+G + +M + P
Sbjct: 1006 LPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYE-KMAKATGKLKPT 1064
Query: 215 RLEMIFAKFDEVQSS----------------GGMILSVCKDKSFDDEESVDGNRPSSAAS 258
+ + A ++ + + GG + + S E+ + ++S
Sbjct: 1065 SKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI-------SSS 1117
Query: 259 AFKVPAPKTSGNPANSARKPGSAGGPKVGGAS--KEGGAGAVDEDDFIKAFTDVPSIQIY 316
P PK + P S+ K SA G K+ + KE DED F VP+ +
Sbjct: 1118 TEPKPDPKKAKAPGLSS-KAKSAQGKKMPSKTSLKE------DEDKSGPIFIVVPNGKEQ 1170
Query: 317 SSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCF---FQH------- 366
++ E+ L ++ + + D+ LK S VA Q + F FQH
Sbjct: 1171 RMKD-EKGLKVLKWNFTTPR---DEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAV 1226
Query: 367 ---------------LRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDH----G 407
L L+ L L D + V+ +A + L T+L + H
Sbjct: 1227 MVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKALEYLKLLFTLLSEEEYHLTENE 1286
Query: 408 AEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFE 467
A + +P L V V+ A + + ++ P I SK+ R E
Sbjct: 1287 ASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLE 1346
Query: 468 FLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYN 527
L L++ + + + ++ I I D D R A T + + N + L
Sbjct: 1347 ELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIG 1406
Query: 528 SLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAG 587
+L L+ +K S S + Q + N ++ P A +S+
Sbjct: 1407 NLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNISSNANMLRKGP---AEDMSSK 1463
Query: 588 SSKASSLPG 596
++A S+ G
Sbjct: 1464 LNQARSMSG 1472
Score = 47.8 bits (112), Expect = 8e-05
Identities = 62/261 (23%), Positives = 105/261 (40%), Gaps = 14/261 (5%)
Query: 44 DLGRLGKTVDALTGWVGS-SNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGD 102
+ G V AL VG +N + + + L+ L +F Y V+ ++++ +
Sbjct: 313 EAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKE 372
Query: 103 AKDKVRDEAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQP 162
K +V Q I + I E + + +KN ++ L + + A
Sbjct: 373 KKPQVVQALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTAST 431
Query: 163 LVISKLIPHLCILF---GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMI 219
L S L P L DS +VRDAA A+ + VGEK ++ + + +L+ I
Sbjct: 432 LPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKA-VNPFLADVDKLKLDKI 490
Query: 220 FAKFDEVQSSGGMILSVCKDKSFDDEESVDGNRPSSAASAFK----VPAPKTSGNPANSA 275
++V+ G + DK + + + G +S A+ K + APK P A
Sbjct: 491 KECSEKVELIHGKKAGLAADKK--EFKPLPGRTAASGAAGDKDTKDISAPKP--GPLKKA 546
Query: 276 RKPGSAGGPKVGGASKEGGAG 296
+ G PK G + GGAG
Sbjct: 547 PAAKAGGPPKKGKPAAPGGAG 567
Score = 39.3 bits (90), Expect = 0.029
Identities = 52/235 (22%), Positives = 97/235 (41%), Gaps = 12/235 (5%)
Query: 1255 DDADQFPDDLSLDHSDLVAELLKELSNHNERVE-----ERKIALYELMKLTQEESFSVWD 1309
DD D+ P + + + V L K + +++E ERK AL + L + D
Sbjct: 257 DDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGD 316
Query: 1310 EHFKTILLLLLETLG-DKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPH 1368
+ ++ L + +G D + ALA K L + +F YA V LE K+
Sbjct: 317 --YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKK 374
Query: 1369 KEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETL-N 1427
+VV++ +EA + + + + + + ++ + I + + TL
Sbjct: 375 PQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPK 434
Query: 1428 LLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDE-LKPHLSQLTGSKMKL 1481
LL L++ ++S VR A L V+G++ + P L+ + K+KL
Sbjct: 435 SLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV--DKLKL 487
>gi|57164942 colonic and hepatic tumor over-expressed protein
isoform a [Homo sapiens]
Length = 2032
Score = 57.8 bits (138), Expect = 8e-08
Identities = 57/253 (22%), Positives = 110/253 (43%), Gaps = 10/253 (3%)
Query: 57 GWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLIL 116
GW +N++V M L I+ A + + K+ +V+ L+D++GD K + A+ +
Sbjct: 649 GWK-ETNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVK--CGNNAKEAMT 704
Query: 117 KLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILF 176
+ + P + ++ F KN +++ L + FG L + I ++
Sbjct: 705 AIAEACMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTAL 764
Query: 177 GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEV--QSSGGMIL 234
+N VR AAI + +Y +VG +RM + PA L I A+F+++ QS
Sbjct: 765 AATNPAVRTAAITLLGVMYLYVGPSLRM--FFEDEKPALLSQIDAEFEKMQGQSPPAPTR 822
Query: 235 SVCKDKSFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGP--KVGGASKE 292
+ K + +E DG+ P ++ P+T + ++ G K+ +
Sbjct: 823 GISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLD 882
Query: 293 GGAGAVDEDDFIK 305
AG +++ FI+
Sbjct: 883 EVAGIINDAKFIQ 895
Score = 55.8 bits (133), Expect = 3e-07
Identities = 86/372 (23%), Positives = 143/372 (38%), Gaps = 59/372 (15%)
Query: 50 KTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRD 109
K + + +V SN V L GLE +V+ K+ +V + K K ++
Sbjct: 48 KFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKE 107
Query: 110 EAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLI 169
+ L ++ + + E+L G +KN + L + L+ FG++ +++ +I
Sbjct: 108 LGIEICLMYIE-IEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPII 166
Query: 170 PHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSS 229
L LF VRD A L VEIYR + + +R L + I +L+ +
Sbjct: 167 KVLPKLFESREKAVRDEAKLIAVEIYRWIRDALRPPL--QNINSVQLKEL---------- 214
Query: 230 GGMILSVCKDKSFDDEESVDGNRPSSAASAFKVPAP----KTSGNPANSARKPGSAGGPK 285
+EE V P+SA P P ++ + SAGG
Sbjct: 215 --------------EEEWV--KLPTSA------PRPTRFLRSQQELEAKLEQQQSAGGDA 252
Query: 286 VGGASKEGGAGAVDEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSD--DKHDWDQRA 343
GG D+ D +VP I Y E E L+K+ + D + W +R
Sbjct: 253 EGGG---------DDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERK 297
Query: 344 NALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNK 403
AL+ + L+ + + L+ K+ KD +V A + L+ L K
Sbjct: 298 EALESVEVLIKNPKLEAG---DYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKK 354
Query: 404 FDHGAEAIVPTL 415
F A +VPT+
Sbjct: 355 FGQYAGHVVPTI 366
Score = 55.1 bits (131), Expect = 5e-07
Identities = 128/609 (21%), Positives = 222/609 (36%), Gaps = 70/609 (11%)
Query: 36 GAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVA 95
G I+D + +G+ AL G + SN + L IL + K +V + +
Sbjct: 886 GIINDAKFIQPNIGELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIP 945
Query: 96 LIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYI-WEQLASGFKHKNFRSREGVCLCLIET 154
+I +GD+K+ VR A + +Q ++ E L+ K +N R+ + L E
Sbjct: 946 IITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEK 1005
Query: 155 LNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPA 214
L + P + +PHL D N VR A A+ H+G + +M + P
Sbjct: 1006 LPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYE-KMAKATGKLKPT 1064
Query: 215 RLEMIFAKFDEVQSS----------------GGMILSVCKDKSFDDEESVDGNRPSSAAS 258
+ + A ++ + + GG + + S E+ + ++S
Sbjct: 1065 SKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI-------SSS 1117
Query: 259 AFKVPAPKTSGNPANSARKPGSAGGPKVGGAS--KEGGAGAVDEDDFIKAFTDVPSIQIY 316
P PK + P S+ K SA G K+ + KE DED F VP+ +
Sbjct: 1118 TEPKPDPKKAKAPGLSS-KAKSAQGKKMPSKTSLKE------DEDKSGPIFIVVPNGKEQ 1170
Query: 317 SSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCF---FQH------- 366
++ E+ L ++ + + D+ LK S VA Q + F FQH
Sbjct: 1171 RMKD-EKGLKVLKWNFTTPR---DEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAV 1226
Query: 367 ---------------LRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDH----G 407
L L+ L L D + V+ +A + L T+L + H
Sbjct: 1227 MVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKALEYLKLLFTLLSEEEYHLTENE 1286
Query: 408 AEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFE 467
A + +P L V V+ A + + ++ P I SK+ R E
Sbjct: 1287 ASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLE 1346
Query: 468 FLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYN 527
L L++ + + + ++ I I D D R A T + + N + L
Sbjct: 1347 ELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIG 1406
Query: 528 SLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAG 587
+L L+ +K S S + Q + N ++ P A +S+
Sbjct: 1407 NLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNISSNANMLRKGP---AEDMSSK 1463
Query: 588 SSKASSLPG 596
++A S+ G
Sbjct: 1464 LNQARSMSG 1472
Score = 47.8 bits (112), Expect = 8e-05
Identities = 62/261 (23%), Positives = 105/261 (40%), Gaps = 14/261 (5%)
Query: 44 DLGRLGKTVDALTGWVGS-SNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGD 102
+ G V AL VG +N + + + L+ L +F Y V+ ++++ +
Sbjct: 313 EAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKE 372
Query: 103 AKDKVRDEAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQP 162
K +V Q I + I E + + +KN ++ L + + A
Sbjct: 373 KKPQVVQALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTAST 431
Query: 163 LVISKLIPHLCILF---GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMI 219
L S L P L DS +VRDAA A+ + VGEK ++ + + +L+ I
Sbjct: 432 LPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKA-VNPFLADVDKLKLDKI 490
Query: 220 FAKFDEVQSSGGMILSVCKDKSFDDEESVDGNRPSSAASAFK----VPAPKTSGNPANSA 275
++V+ G + DK + + + G +S A+ K + APK P A
Sbjct: 491 KECSEKVELIHGKKAGLAADKK--EFKPLPGRTAASGAAGDKDTKDISAPKP--GPLKKA 546
Query: 276 RKPGSAGGPKVGGASKEGGAG 296
+ G PK G + GGAG
Sbjct: 547 PAAKAGGPPKKGKPAAPGGAG 567
Score = 39.3 bits (90), Expect = 0.029
Identities = 52/235 (22%), Positives = 97/235 (41%), Gaps = 12/235 (5%)
Query: 1255 DDADQFPDDLSLDHSDLVAELLKELSNHNERVE-----ERKIALYELMKLTQEESFSVWD 1309
DD D+ P + + + V L K + +++E ERK AL + L + D
Sbjct: 257 DDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGD 316
Query: 1310 EHFKTILLLLLETLG-DKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPH 1368
+ ++ L + +G D + ALA K L + +F YA V LE K+
Sbjct: 317 --YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKK 374
Query: 1369 KEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETL-N 1427
+VV++ +EA + + + + + + ++ + I + + TL
Sbjct: 375 PQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPK 434
Query: 1428 LLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDE-LKPHLSQLTGSKMKL 1481
LL L++ ++S VR A L V+G++ + P L+ + K+KL
Sbjct: 435 SLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV--DKLKL 487
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 50.8 bits (120), Expect = 1e-05
Identities = 74/343 (21%), Positives = 130/343 (37%), Gaps = 18/343 (5%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSR 602
SS S S SD SS S +S N S S+ + + S+ SS +S S S
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Query: 603 SDIDVNAAAGAKAHHAAGQSVRSGRL----GAGALNAGSYASLEDTSDKLDGTASEDGRV 658
S N++ + + ++ S S + + ++ ++ D+S+ D + S D
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 659 RAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV 718
++ + + +DS S + S S GS S S R ++ + + S
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 719 NSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRS 778
+S+ + ++ S S ++ S + SS S S S + +S D S
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 779 FQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDAN 838
S SS S S ++ N+ + +D+ S +S D ++
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS----------SDSSNSSDSSD 987
Query: 839 SDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSE 881
S SS S+ S SS + + D ++ N SSN S+
Sbjct: 988 SSDSSDSSDSSDSSNSSD----SSDSSDSSDSSNSSDSSNSSD 1026
Score = 43.1 bits (100), Expect = 0.002
Identities = 68/341 (19%), Positives = 127/341 (37%), Gaps = 12/341 (3%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRS 603
S ++ S+ SS+SS S S+ ++N S + + S +S+ S S S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSS---DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 604 DIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLS 663
N++ + + ++ S + + N+ + D+S+ D + S D + S
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 664 APLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASA 723
++ +DS S + S S S S + S S+ +S+ +
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS-----SDSSDS 947
Query: 724 QKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLG 783
S S S ++ S S + SS S S S + S D+S +
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 784 PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASS 843
S SS S S ++ N+ + + + + S +S D ++S SS
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 844 ACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKE 884
S+ S SS + ++ D ++ N SS+ S+ +
Sbjct: 1068 DSSDSSDSSDSSD----SSESSDSSDSSNSSDSSDSSDSSD 1104
Score = 42.0 bits (97), Expect = 0.004
Identities = 67/334 (20%), Positives = 122/334 (36%), Gaps = 3/334 (0%)
Query: 553 SDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAAG 612
SD ++S S + N + + + + SS +S+ S S SD + ++
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578
Query: 613 AKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNA 672
+ S S + + N+ + D+SD D + S D + + S + ++
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
Query: 673 KADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRS 732
K+DS + + S S S ++ + + S NS+ + S S
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 733 QGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYGISQSS 792
S + S + SS + S S +S S S S S S
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 793 RLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESY-GMHSDDDANSDASSACSERSYS 851
SS+ S + SD ++ + + +S +S D +NS SS S+ S S
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818
Query: 852 SRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEG 885
+ S + + D ++ N SS+ S+ +G
Sbjct: 819 DSSNSSDS--SNSSDSSDSSNSSDSSDSSDSSDG 850
Score = 39.3 bits (90), Expect = 0.029
Identities = 67/333 (20%), Positives = 121/333 (36%), Gaps = 9/333 (2%)
Query: 552 QSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAA 611
+SD S S S +S N SS S ++ S + SS + S S S S N++
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS--DSDSSDSSNSSD 603
Query: 612 GAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGN 671
+ + ++ S S + + ++ S + D+ K D + S + + +
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 672 AKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPR 731
+DS S + S S S S ++ S+ SS +S S+ S
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSD-------SSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 732 SQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYGISQS 791
S + + + SS S S S ++ S D+S + S S
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 792 SRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASSACSERSYS 851
S S+S + N+ + + + + S SD +SD+S++ S
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 852 SRNGSIPTYMRQTEDVAEVLNRCASSNWSERKE 884
+ + S + ++ NR SSN S+ +
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Score = 38.9 bits (89), Expect = 0.038
Identities = 42/179 (23%), Positives = 74/179 (41%), Gaps = 11/179 (6%)
Query: 1093 NTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSS 1152
++ N + SS S + + S ++ SS + +N+S + S ++ D +++ NS D +S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD-SSDSSNSSDSSNS 806
Query: 1153 LRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQTALDN 1212
+ S S D + + D DS SD D++D S + N
Sbjct: 807 SDS-----SDSSDSSDSDSSNSSDSSNSSDSSDSS----NSSDSSDSSDSSDGSDSDSSN 857
Query: 1213 KASLLHSMPTH-SSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSD 1270
++ +S + SS S + + SDS N S ++ D+D S D SD
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Score = 37.7 bits (86), Expect = 0.084
Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 7/185 (3%)
Query: 1092 RNTGNGTQSSMG----SPLTRPTPRSPANWSSPLTSPTNTSQNT---LSPSAFDYDTENM 1144
++ GNG+ S S T T S +N + + N ++ S S+ +++
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 1145 NSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATD 1204
NS D S + + S D + DS D + SD D++D
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 1205 SSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDL 1264
SS + D+ S S + S S D N + SD+ + S + D+ D
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 1265 SLDHS 1269
S S
Sbjct: 679 SSSDS 683
Score = 36.2 bits (82), Expect = 0.25
Identities = 66/346 (19%), Positives = 120/346 (34%), Gaps = 5/346 (1%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFS-SKWSTANPSTVAGRVSAGSSKASSLPGSLQRSR 602
SG S SS SS S + S S S +N S+ + + SS +S S +
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 603 SDIDVNAAAGAKAHHAAGQSVRS----GRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658
SD ++ + + + +S + ++ S +S ++SD D + S D
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 659 RAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV 718
+ S ++ + S S S S + S + ++ S S
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 719 NSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRS 778
NS+ + + S + S + SS S S S + S D+S +
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 779 FQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDAN 838
S SS S+S + ++ + + +D+ S+ +
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 839 SDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKE 884
SD+S + S N S + + D ++ N SS+ S+ E
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Score = 36.2 bits (82), Expect = 0.25
Identities = 39/178 (21%), Positives = 66/178 (37%), Gaps = 14/178 (7%)
Query: 1093 NTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSS 1152
++ + + SS S + + S ++ SS S ++ S++ S S D+ + NS D
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS--- 650
Query: 1153 LRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQTALDN 1212
S S + S D SD D++DSS ++ +
Sbjct: 651 -----------SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699
Query: 1213 KASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSD 1270
++S S S D + N SDS S + + + D +D S D SD
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Score = 35.4 bits (80), Expect = 0.42
Identities = 38/166 (22%), Positives = 62/166 (37%), Gaps = 22/166 (13%)
Query: 1123 SPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKD 1182
S T + N+ ++D+D ++M +D SS E+ N S+ D N + D+ +
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSS----DESNGNDDANSESDNNSSSRGDASYN 494
Query: 1183 DGDSMCGGPGMSDPRAGGDATDSSQTA------------------LDNKASLLHSMPTHS 1224
+S G G A D +DS+ D+ S + S
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 1225 SPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSD 1270
S S + + SDS S + S+ D D+ D S D S+
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Score = 32.7 bits (73), Expect = 2.7
Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 2/178 (1%)
Query: 1093 NTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSS 1152
++ + + SS S + + + S S + S++ S S ++N +S D +S
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 1153 LRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQTALDN 1212
+ + S S + DS S S + D++DSS ++ N
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 1213 KASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSD 1270
+ S + SS S + + SDS + + S ++ D+ D S D SD
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD--SSDSSD 778
Score = 32.0 bits (71), Expect = 4.6
Identities = 37/182 (20%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 1093 NTGNGTQSSMGSPLTRPTPRSPANWS----SPLTSPTNTSQNTLSPSAFDYDTENMNSED 1148
N+ + + SS S + + S ++ S S +S +N+S + S S+ D+ N +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 1149 IYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQT 1208
S +++ + + D ++ D +S SD +++DSS +
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-------SDSNDSSNSSDSSDS 797
Query: 1209 ALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDH 1268
+ N + +S + S S D + N SDS + + S + D+ D D
Sbjct: 798 S--NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 1269 SD 1270
S+
Sbjct: 856 SN 857
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.4 bits (119), Expect = 1e-05
Identities = 92/387 (23%), Positives = 157/387 (40%), Gaps = 39/387 (10%)
Query: 501 AEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQ-SDRSSSS 559
A++R A M L + A + N +P + L + + A+L S S +
Sbjct: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGT 2316
Query: 560 SQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHA- 618
+ N P SS+ A S A V S+ A++ P ++ SR+ + A+ A A
Sbjct: 2317 PPTAANYPSSSRTPQAPAS--ANLVGPRSAHATA-PVNIAGSRTAAALAPASLTSARMAP 2373
Query: 619 --AGQSVRSGRLGAGALNAGSYAS----LEDTSDKLDGTASEDGRVRAKLS-APLAGMGN 671
+G ++ S R+ A S + L+ + +A R+ ++ + +P + MG
Sbjct: 2374 ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433
Query: 672 AKADS-----------------RGRSRTKMVSQSQP--GSRSGSPGRVLTTTALSTVSSG 712
A + S +SR +++Q+ P GS+S S G V TTT+ + +G
Sbjct: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRC-LIAQTTPVAGSQSLSSGAVATTTSSAGDHNG 2492
Query: 713 VQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRD 772
+ V + P S G + ++ + L A+ R S S S +S SS
Sbjct: 2493 MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 773 TSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADAL---KKPARRRYESY 829
+S S G S + V+ RV + +EAV + PA+R+ S
Sbjct: 2553 SSSSGSSSSDSEG----SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608
Query: 830 GMHSDDDANSDASSACSERSYSSRNGS 856
S ++S +SS+ S S SS + S
Sbjct: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Score = 50.1 bits (118), Expect = 2e-05
Identities = 92/391 (23%), Positives = 143/391 (36%), Gaps = 27/391 (6%)
Query: 491 TIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASL 550
T +G + D+ +A R+ P E L P ++S +VA
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
Query: 551 PQSDRSSSSSQESLN-RPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNA 609
P RS S S + L+ +P +A+P + S+ SKA + QRSRS
Sbjct: 1532 PLGQRSRSGSSQELDVKP------SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585
Query: 610 AAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGM 669
+ ++ +S S + A S D+S + A R++ + G
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 670 GNAKADSRGRSRTKMVSQSQP-------GSRSGSPGRVLTTTALSTVSSGVQRVLVNSAS 722
G + G S T+ + P GSRS + + T SS L A
Sbjct: 1646 GPSP---EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
Query: 723 AQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPV----RS 778
+RS+ S +R +P R + S P P+ SR SS T RS
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762
Query: 779 FQPLGPGYGISQS-SRLSSSVSAMRVLNTGSDVEEA----VADALKKPARRRYESYGMHS 833
P G S+S SR + + R +GS + + + + RRR G HS
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
Query: 834 DDDANSDASSACSERSYSSRNGSIPTYMRQT 864
A + SS S R R+ + PT +++
Sbjct: 1823 RSPARQE-SSRTSSRRRRGRSRTPPTSRKRS 1852
Score = 48.5 bits (114), Expect = 5e-05
Identities = 76/315 (24%), Positives = 120/315 (38%), Gaps = 23/315 (7%)
Query: 555 RSSSSSQESLNRPFSSKWSTANPSTVAGRVSA----GSSKASSLPGSLQRSRSDIDVNAA 610
RS + ++ +R S +W + + GR + G S++ PG RSR+ +
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPG-WSRSRNTQRRGRS 554
Query: 611 AGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLA-GM 669
A+ + +S + A S T + + R R++ P G
Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
Query: 670 GNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKI 729
++ +R RSRT+ S + SRS SP R SG R + + RS+
Sbjct: 615 SRSRTPARRRSRTR--SPVRRRSRSRSPAR----------RSGRSRSRTPARRGRSRSRT 662
Query: 730 PRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYGIS 789
P +G SR +P+R S SR P +G SR SR R S RS G + +
Sbjct: 663 PARRGRSRSRTPARRSGRSRSRTP---ARRGRSR--SRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 790 QSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASSACSERS 849
R S S+ R + + + +++ + + R S S S A S S R
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 850 YSSRNGSIPTYMRQT 864
S + P QT
Sbjct: 778 SLSGSSPCPKQKSQT 792
Score = 42.0 bits (97), Expect = 0.004
Identities = 81/328 (24%), Positives = 120/328 (36%), Gaps = 35/328 (10%)
Query: 537 LQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPG 596
L Y + SG S P DR+ S + S P S+ ++ + + R+ S+ S LP
Sbjct: 2387 LSAYERVSGRT-SPPLLDRARSRTPPSA--PSQSRMTSERAPSPSSRMGQAPSQ-SLLPP 2442
Query: 597 SLQRSRSDI-----DVNAAAGAKAHHAAG-QSVRSGRLGAGALNAGSYASLEDTSDKLDG 650
+ + RS + D + A+ AG QS+ SG + +AG + + S G
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGM--LSVPAPG 2500
Query: 651 TASED-----GRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTA 705
D A+ + LA + AK RS + S S S S S +++
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAK---ERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557
Query: 706 LSTVSSGVQRVLVNSASAQKR--SKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSR 763
S+ S + V A KR S P + RE P + A+ R S S S
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617
Query: 764 EASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPAR 823
+S SS +S S SS SSS S+ ++ + AL KPA
Sbjct: 2618 SSSSSSSSSSSS-------------SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
Query: 824 RRYESYGMHSDDDANSDASSACSERSYS 851
+ G S RS S
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSLS 2692
Score = 33.1 bits (74), Expect = 2.1
Identities = 71/288 (24%), Positives = 113/288 (39%), Gaps = 38/288 (13%)
Query: 552 QSDRSSSSSQESLNRPFSSKWSTANPS-TVAGRVSAGSSKASSLPGSLQRSRSDIDVNAA 610
+ RSS + P + S ++P T R+S S ASS P + RSR+ +
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET--RSRTPPRHRRS 1727
Query: 611 AGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDK-----LDGTASEDGRVRAKLSAP 665
+ A +S S R + + S S L + S R + + +
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 666 LAGMGNAKADSR----GRSRTKMVSQSQPGS--RSGSPGRVLTTTALSTVSSGVQRVLVN 719
G++++ SR RSR+++ + + GS S SP R ++ S G R
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR---T 1844
Query: 720 SASAQKRSKIPRSQGCSREASPSRLSVA--RSSRIPRPSVSQGCSREASRESSRDTSPVR 777
+++KRS+ R+ + S SR S A R SR P +S+ R S TSPV
Sbjct: 1845 PPTSRKRSR-SRTSPAPWKRSRSRASPATHRRSRSRTPLISR-------RRSRSRTSPVS 1896
Query: 778 SFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRR 825
+ SR +SV+ R + S V + + P RR
Sbjct: 1897 -----------RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 49.3 bits (116), Expect = 3e-05
Identities = 75/312 (24%), Positives = 121/312 (38%), Gaps = 42/312 (13%)
Query: 626 GRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLA------GMGNAKADSRGR 679
GR G + SY+ ++ +KLDGT ++R P + + + SR R
Sbjct: 138 GRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSR 197
Query: 680 SRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREA 739
SR S+S+ GS S + + + + S R + + ++ RSK +S+ S+E
Sbjct: 198 SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR---SRSQSRSRSKKEKSRSPSKEK 254
Query: 740 SPSRLSVARSSR----------------IPRPSVSQGCSREASRESSRDTSPVRSFQPLG 783
S SR A SR + +P S+ SR S+ SR S R +
Sbjct: 255 SRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK-SRSPSRHKSKSKSRSRSQERRVEEEK 313
Query: 784 PG---YGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSD 840
G G SQ L S S R + G + + + K R+ + S + S
Sbjct: 314 RGSVSRGRSQEKSLRQSRSRSR--SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSR 371
Query: 841 ASSACSERSYSSRNGSI-PTYMRQTEDVAEVLNRCAS----------SNWSERKEGLLGL 889
+ S S + S R+ + ++ ED +R S + S ++EG
Sbjct: 372 SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGES 431
Query: 890 QNLLKNQRTLSR 901
+N NQ T SR
Sbjct: 432 ENAGTNQETRSR 443
Score = 40.0 bits (92), Expect = 0.017
Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 44/309 (14%)
Query: 508 RKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRP 567
R++Y R+H + + ++ S S ++ S S + RS S S+ S +R
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR-SQSRS 240
Query: 568 FSSKWSTANPSTVAGRV---SAGSSKASSLPGSLQRSRSDIDVNAAAG-AKAHHAAGQSV 623
S K + +PS R SAG S++ S + ++ +++ +V + + H +
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
Query: 624 RS------------GRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGN 671
RS G + G S S G+ S R R+K G
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-RSRSKSKDKRKGRKR 359
Query: 672 AKADSRGRSRTKMVSQ----------SQPGS------------RSGSPGRVLTTTALSTV 709
++ +SR RSR++ S+ S+ GS +S SP R ++
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 710 SSGVQRV----LVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREA 765
S QR N+ + Q+ RS S+ PS S S S+ SR A
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
Query: 766 SRESSRDTS 774
SR SR S
Sbjct: 480 SRSPSRSRS 488
Score = 32.3 bits (72), Expect = 3.5
Identities = 46/182 (25%), Positives = 67/182 (36%), Gaps = 24/182 (13%)
Query: 532 SYQKSLQTYLKSSGSVASLPQSDRSSSSS-----------QESLNRPFSSKWSTANPSTV 580
S +KSL+ S S RS S S +ES +R S S +
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
Query: 581 AGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYAS 640
+ R S S RS+S + + + H + S R GR + NAG+
Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGR--GESENAGTNQE 439
Query: 641 LEDTS---DKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSP 697
S K + R R+K ++ K SR +SR++ S+S SRS S
Sbjct: 440 TRSRSRSNSKSKPNLPSESRSRSKSAS--------KTRSRSKSRSRSASRSPSRSRSRSH 491
Query: 698 GR 699
R
Sbjct: 492 SR 493
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 47.8 bits (112), Expect = 8e-05
Identities = 58/201 (28%), Positives = 83/201 (41%), Gaps = 19/201 (9%)
Query: 627 RLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVS 686
R G + SY+ ++ DKLDGT +R P + + SR RSR++ S
Sbjct: 145 RTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRS 204
Query: 687 QSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKI---PRSQGCSREASPSR 743
+S+ S S R ++ + + S R S + RSK P+S S S SR
Sbjct: 205 RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSR 264
Query: 744 ------LSVARS-SRIPRPSVSQGC-SREASRESSRDTSPV-------RSFQPLGPGYGI 788
S +RS SR P+ + S+ SR SR SP+ RS P P
Sbjct: 265 SKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSP-PPKRAT 323
Query: 789 SQSSRLSSSVSAMRVLNTGSD 809
S+S S S S R ++ D
Sbjct: 324 SRSRSRSRSKSRSRSRSSSRD 344
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 46.2 bits (108), Expect = 2e-04
Identities = 76/308 (24%), Positives = 116/308 (37%), Gaps = 25/308 (8%)
Query: 503 ARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSS----- 557
AR ++R R+H A +++ + S G AS + RSS
Sbjct: 1622 AREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERH 1681
Query: 558 -SSSQESLNRPFSSKWSTANPSTVAG----RVSAGSSKASSLPGSLQRSRSDIDVNAAAG 612
S Q+S + S S+V G R S+GS + S S + + + AG
Sbjct: 1682 GSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAG 1741
Query: 613 AKAHHAAGQSVRSGRLGAGALNAGSY---ASLEDTSDKLDGTA--SEDGRVRAKLSAPLA 667
H + Q G+ G + +GS+ S + S+ G S GR R++
Sbjct: 1742 P--HQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR-HEQAR 1798
Query: 668 GMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRS 727
A G+ + PGS G GR + S SSG + ++Q+RS
Sbjct: 1799 DSSRHSASQEGQDTIR----GHPGSSRG--GRQGSHYEQSVDSSGHSGSHHSHTTSQERS 1852
Query: 728 KIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYG 787
+ R Q SR S + +S R S S+ + +SSR S V Q GP
Sbjct: 1853 DVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRH-SQVGQGQSSGPRTS 1911
Query: 788 ISQSSRLS 795
+Q S +S
Sbjct: 1912 RNQGSSVS 1919
Score = 40.8 bits (94), Expect = 0.010
Identities = 91/401 (22%), Positives = 138/401 (34%), Gaps = 82/401 (20%)
Query: 498 DADAEARVEARKTYMGL--RNHFPGEAETLYN-----------------SLEPSYQKSLQ 538
D+D+E E + + G RNH E L + S + S Q +
Sbjct: 2894 DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTR 2953
Query: 539 -TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWS---------TANPSTVAGRVSAGS 588
T S G AS + RSS+ + + S+ S ++ +G
Sbjct: 2954 HTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSG 3013
Query: 589 SKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSY---ASLEDTS 645
S+AS G + S + V+A A +H + Q GR G + ++GS+ S + S
Sbjct: 3014 SQASDNEGHSEDSDTQ-SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 3072
Query: 646 DKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQS----QPGSRSGSPGRVL 701
+ G R R G + +A R Q PGS G GR
Sbjct: 3073 ESSHGWTGPSTRGRQ-------GSRHEQAQDSSRHSASQYGQDTIRGHPGSSRG--GRQG 3123
Query: 702 TTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGC 761
S SSG + ++Q RS R Q SR AS + + +S R SVS+
Sbjct: 3124 YHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHH 3183
Query: 762 SREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKP 821
+ SR + V+ G S+ SR S
Sbjct: 3184 EASTHADISRHSQAVQ---------GQSEGSRRS-------------------------- 3208
Query: 822 ARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMR 862
RR+ S SD + +S+ S S + + GS+ R
Sbjct: 3209 -RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSR 3248
Score = 37.4 bits (85), Expect = 0.11
Identities = 81/328 (24%), Positives = 123/328 (37%), Gaps = 24/328 (7%)
Query: 479 HSLERHAAVLVETIKKGIHDAD---AEARVEARKTY----MGLRNHFPGEAETLYNSLEP 531
HS H+ T +G DA + +R +RKTY G + G +S
Sbjct: 2163 HSGSHHS----HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
Query: 532 SYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKA 591
S + SL +SSG S P R SS SQ+S + S + S A R GS++
Sbjct: 2219 SSRHSLVGQGQSSGPRTSRP---RGSSVSQDSDSEGHSE--DSERRSGSASRNHHGSAQE 2273
Query: 592 SSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGT 651
S GS + RS + A G H+A S +SG A + G AS + + G
Sbjct: 2274 QSRDGS-RHPRSHHEDRAGHG----HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE 2328
Query: 652 ASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSS 711
++ S+ +G+G+ +A S R S S S T ++S
Sbjct: 2329 RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQ 2388
Query: 712 GVQRVLVNSASAQKRS--KIPRSQGCSREASPSRLSVARSSRIPRPSVS-QGCSREASRE 768
+ S + RS + RS + S S + R + QG + +R+
Sbjct: 2389 AGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARD 2448
Query: 769 SSRDTSPVRSFQPLGPGYGISQSSRLSS 796
SSR ++ + G S R S
Sbjct: 2449 SSRHSTSQEGQDTIHGHPGSSSGGRQGS 2476
Score = 37.0 bits (84), Expect = 0.14
Identities = 76/334 (22%), Positives = 111/334 (33%), Gaps = 61/334 (18%)
Query: 539 TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSA--------GSSK 590
T SSG AS + RSS+ + S S+ + T G+ S+ GSS
Sbjct: 685 TQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSG 744
Query: 591 ASSLPGSLQRSRSDIDVNAAAGAKAHH-AAGQSVRSGRLGAGALNAGSY---ASLEDTSD 646
+ + SD + G HH + Q R G + +GS+ S S+
Sbjct: 745 SQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSE 804
Query: 647 KLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSR----SGSPGRVLT 702
G VR G+ +R SR Q R S GR +
Sbjct: 805 SSHGWTGPSTGVR---------QGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGS 855
Query: 703 TTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCS 762
S SG + ++Q RS R Q SR AS R++R +
Sbjct: 856 HHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS-------RTTR----------N 898
Query: 763 REASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPA 822
E SR+ SR + S+ SS R G E + +
Sbjct: 899 EEQSRDGSRHSG--------------SRHHEASSHADISRHSQAGQGQSEG-----SRTS 939
Query: 823 RRRYESYGMHSDDDANSDASSACSERSYSSRNGS 856
RR+ S SD + +S+ S S + + GS
Sbjct: 940 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGS 973
Score = 36.6 bits (83), Expect = 0.19
Identities = 86/371 (23%), Positives = 136/371 (36%), Gaps = 41/371 (11%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
+S GS S Q S S + S +WS + A R GS + S GS +
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS-----ASRNHRGSVQEQSRHGS-RHP 3254
Query: 602 RSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAK 661
RS + A G H+A +S +SG A + G AS + + G ++
Sbjct: 3255 RSHHEDRAGHG----HSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSA 3310
Query: 662 LSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSA 721
S+ +G+ +A S R S S S T ++S +
Sbjct: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQE 3370
Query: 722 SAQKRS--KIPRS-----QGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTS 774
SA+ RS + RS Q + E S S R+S R QG E +R+SSR ++
Sbjct: 3371 SARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR----QGSHHEQARDSSRHSA 3426
Query: 775 PVRSFQPLGPGYGISQSSRLSS--SVSAMRVLNTGS----DVEEAVADALKKPARRRYES 828
+ G S+ R S S R ++GS + +DA + + R S
Sbjct: 3427 SQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
Query: 829 YGMHSDD--------------DANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRC 874
+D+ +A++ A S+ +S ++ T Q V++ +
Sbjct: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQ 3546
Query: 875 ASSNWSERKEG 885
S SER G
Sbjct: 3547 GHSEDSERWSG 3557
Score = 35.8 bits (81), Expect = 0.32
Identities = 78/331 (23%), Positives = 115/331 (34%), Gaps = 64/331 (19%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWS---------TANPSTVAGRVSAGSSKASS 593
S G AS + RSS+ + + S+ S ++ +G + S+AS
Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 3666
Query: 594 LPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTAS 653
G + S + V+A A H + Q GR + +GS+ T ++ S
Sbjct: 3667 SEGHSEDSDTQ-SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQ-----S 3720
Query: 654 EDGRVRAKLSAPLAG--MGNAKADSRGRSRTKMVSQSQ------PGSRSGSPGRVLTTTA 705
E RA P G G+ +R SR + Q PGSR G GR +
Sbjct: 3721 ESAHGRA---GPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRG--GRQGSYHE 3775
Query: 706 LSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREA 765
S SG + ++Q RS Q SR AS + +S R S S+
Sbjct: 3776 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEAST 3835
Query: 766 SRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRR 825
+SSR + G G S SR S RR+
Sbjct: 3836 QADSSRHSQS---------GQGESAGSRRS---------------------------RRQ 3859
Query: 826 YESYGMHSDDDANSDASSACSERSYSSRNGS 856
S SD +A + S SE + + +GS
Sbjct: 3860 GSSVSQDSDSEAYPEDSERRSESASRNHHGS 3890
Score = 35.0 bits (79), Expect = 0.55
Identities = 84/377 (22%), Positives = 133/377 (35%), Gaps = 52/377 (13%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
+SSG S Q S S + S +WS + A R GS++ S GS +
Sbjct: 607 QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGS-----ASRNHHGSAQEQSRDGS-RHP 660
Query: 602 RSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTA-SEDGRVRA 660
RS + A G H+A S +SG ++G AS + + G ++++
Sbjct: 661 RSHHEDRAGHG----HSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQS 716
Query: 661 KLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNS 720
S+ +G G+ +A S R S + S T ++S +
Sbjct: 717 ADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQ 776
Query: 721 ASAQKRS--KIPRSQGCSREASPSRLSVARSSRI-PRPSVSQGCSREASRESSRDTSPVR 777
SA+ RS + RS + S + S + P V QG E +R++SR ++
Sbjct: 777 ESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQD 836
Query: 778 SFQPLGPGYGISQSSR-----------------------------LSSSVSAMRVLNTGS 808
+ G S+ R S S R + +
Sbjct: 837 GQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT 896
Query: 809 DVEEAVADALKKPARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVA 868
EE D + R +E+ H+D +S A SE S +SR RQ V+
Sbjct: 897 RNEEQSRDGSRHSGSRHHEA-SSHADISRHSQAGQGQSEGSRTSR--------RQGSSVS 947
Query: 869 EVLNRCASSNWSERKEG 885
+ + S SER G
Sbjct: 948 QDSDSEGHSEDSERWSG 964
Score = 34.3 bits (77), Expect = 0.93
Identities = 56/236 (23%), Positives = 88/236 (37%), Gaps = 13/236 (5%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
+S+G S Q S S + S +WS + A R GS++ S GS +
Sbjct: 3525 QSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGS-----ASRNHRGSAQEQSRDGS-RHP 3578
Query: 602 RSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAK 661
S + A G H+A S +SG A + G AS + + G ++
Sbjct: 3579 TSHHEDRAGHG----HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 3634
Query: 662 LSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSA 721
S+ +G+G+ +A S R S S S T ++S +
Sbjct: 3635 DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
Query: 722 SAQKRS--KIPRSQGCSREASPSRLSVARSSRI-PRPSVSQGCSREASRESSRDTS 774
S + RS + RS + S S + R P QG E +R+SSR ++
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSA 3750
Score = 31.6 bits (70), Expect = 6.1
Identities = 61/265 (23%), Positives = 94/265 (35%), Gaps = 18/265 (6%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
+SSG S Q S S + S +WS + G S S PGS
Sbjct: 1904 QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHED 1963
Query: 602 RSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTA-SEDGRVRA 660
R A H+A S +SG + + G AS + + G ++++
Sbjct: 1964 R----------AGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQS 2013
Query: 661 KLSAPLAGMGNAKADSRGR-SRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGV-QRVLV 718
S+ +G+G+ +A S R S + S SQ G T + + +G Q+
Sbjct: 2014 ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHK 2073
Query: 719 NSASAQKRSKIPRSQGCSREASPSRLSVA-RSSRIPRPSVSQGCSREASRESSRDTSPVR 777
SA Q RS + S S + P QG + +++SSR ++
Sbjct: 2074 ESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE 2133
Query: 778 SFQPL----GPGYGISQSSRLSSSV 798
+ GP G Q S SV
Sbjct: 2134 GQDTIRGHPGPSRGGRQGSHQEQSV 2158
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 46.2 bits (108), Expect = 2e-04
Identities = 63/322 (19%), Positives = 118/322 (36%), Gaps = 13/322 (4%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPST--VAGRVSAGSSKASSLPGSLQR 600
S S A+ S +SS + + N S+ S A+ +T + S+G+S A++ S
Sbjct: 130 SGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189
Query: 601 SRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRA 660
SR+ N+ + + +G S + N A+ ++S G ++ +
Sbjct: 190 SRASTATNSESSTTS---SGASTATNSESRTTSNGAGTATNSESSTTSSGASTA---TNS 243
Query: 661 KLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNS 720
+ S P +G G A + + + + S + S G T + S+ S NS
Sbjct: 244 ESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNS 303
Query: 721 ASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQ 780
S+ S + + S S A +S + S G S + ESS +S +
Sbjct: 304 ESSTTSSGANTATNSDSSTTSSGASTATNSE--SSTTSSGASTATNSESSTTSSGASTAT 361
Query: 781 PLG---PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDA 837
G G S ++ SS + + + + +
Sbjct: 362 NSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTAT 421
Query: 838 NSDASSACSERSYSSRNGSIPT 859
NS++S+ S + ++ +GS T
Sbjct: 422 NSESSTTSSGANTATNSGSSVT 443
Score = 42.4 bits (98), Expect = 0.003
Identities = 62/294 (21%), Positives = 109/294 (37%), Gaps = 27/294 (9%)
Query: 522 AETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVA 581
A T NS + T S S S S ++S S+ + N ++ + + ST +
Sbjct: 177 ASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTA--TNSESSTTS 234
Query: 582 GRVSAGSSKASSLP--GSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYA 639
S ++ SS P G+ + S+ ++ A ++ +V SG + + +
Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294
Query: 640 SLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGR 699
S +T+ + + + G A +DS S + + S + S
Sbjct: 295 SGANTATNSESSTTSSGANTA-----------TNSDSSTTSSGASTATNSESSTTSSGAS 343
Query: 700 VLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQ 759
T + ST SSG +++A S G S + +V+ + S S
Sbjct: 344 TATNSESSTTSSG-------ASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESS 396
Query: 760 GCSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEA 813
S AS ++ ++S V S G + S +SS A N+GS V A
Sbjct: 397 TTSSGASTATNSESSTVSS----GASTATNSESSTTSS-GANTATNSGSSVTSA 445
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 44.7 bits (104), Expect = 7e-04
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 539 TYLKSSGSVASL--PQSDRSSSSSQESLNRPFSSKWSTAN-PSTVAGRVSAGSSKASSLP 595
TY S GS ++ P+SD +S +ES S+ + ++ PST + V +S SS P
Sbjct: 752 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS-P 810
Query: 596 GSLQRSR-------SDIDVNAAAGAKAHHAAG------QSVRSGRLGAGALNAGSYASLE 642
GS + S + A + A G +S S LG + S S+E
Sbjct: 811 GSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSME 870
Query: 643 DT----SDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPG 698
T S G + + +P + A S G S S S+PGS
Sbjct: 871 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH---- 926
Query: 699 RVLTTTAL--STVSSGVQRVLVNSAS---AQKRSKIPRSQGCSREASPSRLSVARSS--- 750
TTA ST + G+ R S S + + +P S P+ ++ S
Sbjct: 927 ----TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTET 982
Query: 751 -RIPRPSVSQGCSREASRESSRDTSPVRSFQPLG-PGYGISQSSRLSSS 797
+P + + G S +++ S SP + P G+S+ S S S
Sbjct: 983 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 1031
Score = 38.9 bits (89), Expect = 0.038
Identities = 75/314 (23%), Positives = 118/314 (37%), Gaps = 32/314 (10%)
Query: 551 PQSDRSSSSSQESL---NRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDV 607
P S SS S+ES +RP S+ + ST VS S+ + S PGS + S
Sbjct: 1014 PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRST 1073
Query: 608 NAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLA 667
A+ + G + G G+ + +L + G V + +P
Sbjct: 1074 TAS-------SLGPESTTFHSGPGS----TETTLLPDNTTASGLLEASTPVHSSTGSPRT 1122
Query: 668 GMGNAKADSR-GRSRTKMVSQSQPGSRSGSPGRVLTTTA---LSTVSSGVQRVLVNSASA 723
+ A + +R G S T QS P S+ P TT+A LST S G +S
Sbjct: 1123 TLSPAGSTTRQGESTT---FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP----SSIPT 1175
Query: 724 QKRSKIPRSQGCSREASPSRLSVARSSRIPRP--SVSQGCSREASR-ESSRDTSPVRSFQ 780
S + G S E++ S + P P S + G E++ SS ++ F
Sbjct: 1176 THFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1235
Query: 781 PLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSD 840
G S+ SR S S + +T S + +++P + + S
Sbjct: 1236 ESSTASGRSEESRTSHSSTT----HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESS 1291
Query: 841 ASSACSERSYSSRN 854
+S SE S +S +
Sbjct: 1292 TTSGRSEESTASHS 1305
>gi|8923040 CDKN2A interacting protein [Homo sapiens]
Length = 580
Score = 44.7 bits (104), Expect = 7e-04
Identities = 72/292 (24%), Positives = 122/292 (41%), Gaps = 29/292 (9%)
Query: 538 QTYLKSSGSV--ASLPQSDRS----SSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKA 591
Q + K+S AS Q + S S+ ES N SS S+ N ST G S S +
Sbjct: 156 QDHAKTSAKTERASAQQENSSTCIGSAIKSESGNSARSSGISSQNSSTSDGDRSVSSQSS 215
Query: 592 SSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDK--LD 649
SS+ + + S A A K A+ S+ + + + + K L+
Sbjct: 216 SSVSSQVTTAGSGKASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALE 275
Query: 650 GTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKM-VSQSQPGSRSGSPGRVLTTTALST 708
G+++ + +++ PL G S G S ++ + S+P S + S G T++ ++
Sbjct: 276 GSSASASQSSSEIEVPLLG-------SSGSSEVELPLLSSKPSSETASSGLTSKTSSEAS 328
Query: 709 VSSGVQR--------VLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQG 760
VSS V + +L +S+ + + S+ S+ A+ S L+ SS+ VS+
Sbjct: 329 VSSSVAKNSSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAA-SLLASKSSSQTSGSLVSKS 387
Query: 761 CSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEE 812
S + + + +S S L P SQSS S S T DV++
Sbjct: 388 TSLASVSQLASKSSSQTSTSQL-PSKSTSQSSESSVKFSCKL---TNEDVKQ 435
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 43.5 bits (101), Expect = 0.002
Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 20/170 (11%)
Query: 612 GAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGN 671
G A + V S + G G+ S S+++T +L+G +AK +P+ G+
Sbjct: 325 GTSGFSPAPKLVESPKEGKGS--KPSPLSVKNTKRRLEGAK------KAKADSPVNGLPK 376
Query: 672 AKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPR 731
+ +SR RSR++ S S+ SRS SP R + + ++ S Q S S + PR
Sbjct: 377 GR-ESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQ-----SRSRSRSDSPPR 430
Query: 732 SQGCSREASPSRLSVARSSR------IPRPSVSQGCSREASRESSRDTSP 775
S S + +R S+ P S S+ SR SR R +P
Sbjct: 431 QAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNP 480
>gi|21361794 TIP120 protein [Homo sapiens]
Length = 1230
Score = 43.5 bits (101), Expect = 0.002
Identities = 41/199 (20%), Positives = 92/199 (46%), Gaps = 21/199 (10%)
Query: 1272 VAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIR 1331
++ LL+++++ ++ + R +A +LM Q++S + D+ + ++ ++L+ L DK ++
Sbjct: 8 ISNLLEKMTSSDK--DFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ 65
Query: 1332 ALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAE--------------E 1377
LA+K L ++ ++ K Y T++ TL + KE +R
Sbjct: 66 NLAVKCLGPLV----SKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPAS 121
Query: 1378 AASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGL 1437
+ S LA ++ + ++ I + D + L A+ + ++ R +N P I+ L
Sbjct: 122 SGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVN-FHPSILTCL 180
Query: 1438 IQGYDNSESSVRKACVFCL 1456
+ + +VRK + L
Sbjct: 181 LPQLTSPRLAVRKRTIIAL 199
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 42.7 bits (99), Expect = 0.003
Identities = 95/392 (24%), Positives = 132/392 (33%), Gaps = 54/392 (13%)
Query: 477 QTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKS 536
Q+ S RH + L + G H + + R +R Y H +++ E S
Sbjct: 1711 QSPSRGRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRSGH-----SSVFGQHESGSGHS 1764
Query: 537 LQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPG 596
SGS Q S+S Q S F + S+ S+ G+ +GSS++SS
Sbjct: 1765 SAYSQHGSGSGHFCSQGQHGSTSGQSST---FDQEGSSTGQSSSHGQHGSGSSQSSSY-- 1819
Query: 597 SLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDG 656
+ +GQS GR G+G+ ++ SY S G +S G
Sbjct: 1820 ----------------GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS----GWSSSSG 1859
Query: 657 RVRAKLSAPLAGMGNAKADS--------RGRSRTKMVSQSQPGSRSGSPGRVLTTTALST 708
R S +G G+ ++ S G S Q GSRSG R + S
Sbjct: 1860 R-HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
Query: 709 VSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRE 768
SS + S S Q G + SPSR R S S G S
Sbjct: 1919 SSSSYGQ--HGSGSRQSLGHGQHGSGSGQSPSPSR---GRHGSGSGQSSSYGPYGSGSGW 1973
Query: 769 SSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYES 828
SS P S G G+ R S S + GS + A + S
Sbjct: 1974 SS-SRGPYES----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSS 2028
Query: 829 YGMHSDDDANSDA----SSACSERSYSSRNGS 856
G H S + S S+ S R GS
Sbjct: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
Score = 40.8 bits (94), Expect = 0.010
Identities = 83/327 (25%), Positives = 123/327 (37%), Gaps = 37/327 (11%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLP-----GS 597
SSGS +S Q S S++SL S +PS GR +GS ++SS
Sbjct: 1446 SSGSSSSYGQH---GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 1502
Query: 598 LQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGR 657
SR + ++ + H +S +S G ++G ++S G +S G+
Sbjct: 1503 WSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSG-HSSTHGQHGSTSGQSSSCGQ 1561
Query: 658 VRAK--LSAPLAGMGNAKADSRGRSRTKMVSQSQPG-SRSGSPGRVLTTTALSTVSSGVQ 714
A S+ G+ + S G R S PG + GS R + + SG
Sbjct: 1562 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR--QSPSYGRHGSGSG 1619
Query: 715 RVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASR--ESSRD 772
R +S+S Q S + S G S S S + S S G + SR +SSR
Sbjct: 1620 R---SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR- 1675
Query: 773 TSPVRSFQPLGPGYGIS--QSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYG 830
G +G S SSR S R S + + + P+R R+ S
Sbjct: 1676 ----------GERHGSSSRSSSRYGQHGSGSR---QSSGHGRQGSGSGQSPSRGRHGSGL 1722
Query: 831 MHSDDDA--NSDASSACSERSYSSRNG 855
HS S + + S Y SR+G
Sbjct: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSG 1749
Score = 40.0 bits (92), Expect = 0.017
Identities = 95/385 (24%), Positives = 136/385 (35%), Gaps = 72/385 (18%)
Query: 483 RHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLK 542
RH + L + G H + + R +R Y H +++ E S
Sbjct: 1247 RHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRSGH-----SSVFGQHESGSGHSSAYSQH 1300
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSR 602
SGS Q S+S Q S F + S+ S+ G +GSS++S
Sbjct: 1301 GSGSGHFCSQGQHGSTSGQSST---FDQEGSSTGQSSSYGHRGSGSSQSS---------- 1347
Query: 603 SDIDVNAAAGAKAHHA-AGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAK 661
G H A +GQS GR G+G+ ++ SY S G +S GR
Sbjct: 1348 ---------GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGS----GWSSSSGR-HGS 1393
Query: 662 LSAPLAGMGNAKADS--------RGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGV 713
S +G G+ ++ S G S Q GSRSG R SSG
Sbjct: 1394 GSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSR----GERHGSSSG- 1448
Query: 714 QRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDT 773
+S+ Q S +S G + S S S PS S+G S +SS
Sbjct: 1449 ----SSSSYGQHGSGSRQSLGHGQHGSGSGQS---------PSPSRGRHGSGSGQSS--- 1492
Query: 774 SPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYES--YGM 831
S+ P G G G S S S S+ ++G E+ + + S
Sbjct: 1493 ----SYSPYGSGSGWSSSRGPYESGSSH---SSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
Query: 832 HSDDDANSDASSACSERSYSSRNGS 856
H + S SS+C + SS S
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSS 1570
Score = 40.0 bits (92), Expect = 0.017
Identities = 77/355 (21%), Positives = 114/355 (32%), Gaps = 72/355 (20%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSK--WSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
SG S + S S Q S P+ S WS++ G +GSS +S L RS
Sbjct: 1473 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR-----GPYESGSSHSSGLGHRESRS 1527
Query: 602 RSDIDVNAAAGAKAHHA---------------------AGQSVRSGRLGAGALNAGSYAS 640
+ H + +GQS G+ G+G+ + Y
Sbjct: 1528 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 1587
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
S + G R S G G+ ++ S G+ + + S G S G+
Sbjct: 1588 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ- 1646
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQG 760
+++ S SG +S Q S+ +S R S SR S S G
Sbjct: 1647 --SSSYSQHGSGSGH---SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701
Query: 761 CSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKK 820
R+ S SP R G G+ S S S +
Sbjct: 1702 HGRQGSGSGQ---SPSRGRHGSGLGHSSSHGQHGSGSG--------------------RS 1738
Query: 821 PARRRYES-------YGMHSDDDANSDASSA--------CSERSYSSRNGSIPTY 860
+R YES +G H +S A S CS+ + S +G T+
Sbjct: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793
Score = 39.7 bits (91), Expect = 0.022
Identities = 85/342 (24%), Positives = 119/342 (34%), Gaps = 37/342 (10%)
Query: 532 SYQKSLQTYLKSSGSVASLPQSDRSSS---SSQESLNRPFSSKW---STANPSTVAGRVS 585
S S Y SG + Q + S S S + FSS+ ST+ S+ +G+
Sbjct: 799 SCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHD 858
Query: 586 AGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTS 645
+ S ++SS S +A+ + +GQS G+ G+G+ + SY S
Sbjct: 859 SSSGQSSSYGQHESASH-----HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
Query: 646 DKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQS-------QPGSRSGSPG 698
G +S GR S +G G+ + + T+ S S Q GSRSG
Sbjct: 914 ----GRSSSSGR-HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
Query: 699 RVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVS 758
R + S SS + S S Q G + SPSR R S S
Sbjct: 969 RSEQHGSSSGSSSSYGQ--HGSGSRQSLGHGQHGSGSGQSPSPSR---GRHGSGSGQSSS 1023
Query: 759 QGCSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADAL 818
G R S SS P S G G+ R S S + GS +
Sbjct: 1024 YGPYRSGSGWSS-SRGPYES----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078
Query: 819 KKPARRRYESYGMHSDDDANSDA----SSACSERSYSSRNGS 856
+ S G H S + S S+ S R GS
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 1120
Score = 39.7 bits (91), Expect = 0.022
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 45/331 (13%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSL-----PGS 597
SSGS +S Q S S++SL S +PS GR +GS ++SS
Sbjct: 1916 SSGSSSSYGQH---GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG 1972
Query: 598 LQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGR 657
SR + + + H +S +S G ++G ++S G +S G+
Sbjct: 1973 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG-HSSTHGQHGSASGQSSSCGQ 2031
Query: 658 VRAK--LSAPLAGMGNAKADSRGRSRTKMVSQSQPG-SRSGSPGRVLTTTALSTVSSGVQ 714
A S+ G+ + S G R S PG + GS R + + SG
Sbjct: 2032 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR--QSPSYGRHGSGSG 2089
Query: 715 RVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASR--ESSRD 772
R +S+S Q + S G S S S + S S G + SR +SSR
Sbjct: 2090 R---SSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR- 2145
Query: 773 TSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALK------KPARRRY 826
G +G SSS S+ R GS ++ + P+R R+
Sbjct: 2146 ----------GERHG-------SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH 2188
Query: 827 ESYGMHSDDDA--NSDASSACSERSYSSRNG 855
S HS S + + S Y SR+G
Sbjct: 2189 GSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Score = 39.3 bits (90), Expect = 0.029
Identities = 79/323 (24%), Positives = 116/323 (35%), Gaps = 29/323 (8%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSL-----PGS 597
SSGS +S Q S S++SL S +PS GR +GS ++SS
Sbjct: 976 SSGSSSSYGQH---GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
Query: 598 LQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGR 657
SR + + + H +S +S G ++G ++S G +S G+
Sbjct: 1033 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG-HSSTHGQHGSTSGQSSSCGQ 1091
Query: 658 VRAK--LSAPLAGMGNAKADSRGRSRTKMVSQSQPG-SRSGSPGRVLTTTALSTVSSGVQ 714
A S+ G+ + S G R S PG + GS R + + SG
Sbjct: 1092 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR--QSPSYGRHGSGSG 1149
Query: 715 RVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTS 774
R +S+S Q S + S G S S S + S S G + SR S + +
Sbjct: 1150 R---SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSR 1205
Query: 775 PVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSD 834
R G Q S S +GS P+R R+ S HS
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSG---------HSPSRGRHGSGLGHSS 1256
Query: 835 DDA--NSDASSACSERSYSSRNG 855
S + + S Y SR+G
Sbjct: 1257 SHGQHGSGSGRSSSRGPYESRSG 1279
Score = 39.3 bits (90), Expect = 0.029
Identities = 71/293 (24%), Positives = 108/293 (36%), Gaps = 22/293 (7%)
Query: 553 SDRSSSSSQESLNRPFSSKW----STANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVN 608
S +SSS Q + SS S ++ S+ GR +GS ++ PG QR
Sbjct: 2023 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---PGHGQRGSGSRQ-- 2077
Query: 609 AAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAG 668
+ + + +G+S SG+ G G + + E +S + + S+ G +G
Sbjct: 2078 SPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQ-SSSYSQHG----------SG 2126
Query: 669 MGNAKADSRGRSRTKMVSQSQP-GSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRS 727
G++ + SR+ S+ + GS SGS R + S SSG R S + R
Sbjct: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRG 2186
Query: 728 KIPRSQGCSREASPSRLSVARSS-RIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGY 786
+ G S RSS R P S S S ES S S G G+
Sbjct: 2187 RHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
Query: 787 GISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANS 839
SQ S+S + GS ++ + + SYG S
Sbjct: 2247 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 2299
Score = 39.3 bits (90), Expect = 0.029
Identities = 69/256 (26%), Positives = 95/256 (37%), Gaps = 59/256 (23%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRS 603
SGS Q S+S Q S F + S+ S+ G+ +GSS++SS
Sbjct: 2242 SGSGHFCSQGQHGSTSGQSST---FDQEGSSTGQSSSHGQHGSGSSQSSSY--------- 2289
Query: 604 DIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLS 663
+ +GQS GR G+G+ ++ SY S G +S GR S
Sbjct: 2290 ---------GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS----GWSSSSGR-HGSGS 2335
Query: 664 APLAGMGNAKADS--------RGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQR 715
+G G+ ++ S G S Q GSRSG R SSG
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR----GERHGSSSG--- 2388
Query: 716 VLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSP 775
+S+ Q S +S G + S S S PS S+G S +SS
Sbjct: 2389 --SSSSYGQHGSGSRQSLGHGQHGSGSGQS---------PSPSRGRHGSGSGQSS----- 2432
Query: 776 VRSFQPLGPGYGISQS 791
S+ P G G G S S
Sbjct: 2433 --SYSPYGSGSGWSSS 2446
Score = 38.9 bits (89), Expect = 0.038
Identities = 74/325 (22%), Positives = 108/325 (33%), Gaps = 10/325 (3%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRS 603
SGS S S S SS S R S+ ++ S G S SS +S
Sbjct: 705 SGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSG 764
Query: 604 DIDVNAAAG---AKAHH--AAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658
+ +G ++ H ++G S G+ G+G + S E S + G +
Sbjct: 765 HGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGS 824
Query: 659 RAKLSAPLAGMGNAKADSR-GRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVL 717
S + G+ + R G + + S Q S SG + S +SG R
Sbjct: 825 GQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH- 883
Query: 718 VNSASAQKRSKIPRSQGCSREASPSR--LSVARSSRIPRPSVSQGCSREASRESSRDTSP 775
S S Q R G + S R RSS R G S +SS S
Sbjct: 884 -GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSS 942
Query: 776 VRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDD 835
+ G G+ S S S + R GS + + R+ +G H
Sbjct: 943 GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1002
Query: 836 DANSDASSACSERSYSSRNGSIPTY 860
S + S S S ++ S Y
Sbjct: 1003 SGQSPSPSRGRHGSGSGQSSSYGPY 1027
Score = 38.9 bits (89), Expect = 0.038
Identities = 79/323 (24%), Positives = 116/323 (35%), Gaps = 29/323 (8%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLP-----GS 597
SSGS +S Q S S++SL S +PS GR +GS ++SS
Sbjct: 2386 SSGSSSSYGQH---GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 2442
Query: 598 LQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGR 657
SR + + + H +S +S G ++G ++S G +S G+
Sbjct: 2443 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG-HSSTHGQHGSTSGQSSSCGQ 2501
Query: 658 VRAK--LSAPLAGMGNAKADSRGRSRTKMVSQSQPG-SRSGSPGRVLTTTALSTVSSGVQ 714
A S+ G+ + S G R S PG + GS R + + SG
Sbjct: 2502 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR--QSPSYGRHGSGSG 2559
Query: 715 RVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTS 774
R +S+S Q S + S G S S S + S S G + SR S + +
Sbjct: 2560 R---SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSR 2615
Query: 775 PVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSD 834
R G Q S S +GS + P+R R+ S HS
Sbjct: 2616 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSG---------QSPSRGRHGSGLGHSS 2666
Query: 835 DDA--NSDASSACSERSYSSRNG 855
S + + S Y SR G
Sbjct: 2667 SHGQHGSGSGRSSSRGPYESRLG 2689
Score = 38.1 bits (87), Expect = 0.065
Identities = 77/316 (24%), Positives = 109/316 (34%), Gaps = 22/316 (6%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKW----STANPSTVAGRVSAGSSKASSL---- 594
SSG +S +SS Q + SS ST+ S+ G+ A S ++SS
Sbjct: 1517 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1576
Query: 595 PGSLQRSRSDIDVNAAAGAKAHHAAG----QSVRSGRLGAGALNAGSYASLEDTSDKLDG 650
GS Q S + + + H G QS GR G+G+ + S + G
Sbjct: 1577 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1636
Query: 651 TASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTAL---- 706
+ S G G+ + G+ ++ QS G R GS R +
Sbjct: 1637 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS-GQSSRGERHGSSSRSSSRYGQHGSG 1695
Query: 707 STVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRL---SVARSSRIPRPSVSQGCSR 763
S SSG R S S Q S+ G +S + S SSR P S S S
Sbjct: 1696 SRQSSGHGRQ--GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 1753
Query: 764 EASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPAR 823
ES S S G G+ SQ S+S + GS ++ +
Sbjct: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 1813
Query: 824 RRYESYGMHSDDDANS 839
+ SYG S
Sbjct: 1814 SQSSSYGQQGSGSGQS 1829
Score = 37.7 bits (86), Expect = 0.084
Identities = 70/293 (23%), Positives = 109/293 (37%), Gaps = 22/293 (7%)
Query: 553 SDRSSSSSQESLNRPFSSKW----STANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVN 608
S +SSS Q + SS S ++ S+ GR +GS ++ PG QR
Sbjct: 1083 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---PGHGQRGSGSRQ-- 1137
Query: 609 AAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAG 668
+ + + +G+S SG+ G+G + + E +S + + S+ G +G
Sbjct: 1138 SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ-SSSYSQHG----------SG 1186
Query: 669 MGNAKADSRGRSRTKMVSQSQP-GSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRS 727
G++ + SR+ S+ + GS SGS + S SSG R S + R
Sbjct: 1187 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
Query: 728 KIPRSQGCSREASPSRLSVARSS-RIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGY 786
+ G S RSS R P S S S ES S S G G+
Sbjct: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
Query: 787 GISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANS 839
SQ S+S + GS ++ + + + YG H S
Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 1359
Score = 37.0 bits (84), Expect = 0.14
Identities = 80/380 (21%), Positives = 124/380 (32%), Gaps = 78/380 (20%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSK--WSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
SG S + S S Q S P+ S WS++ G +GS +S L RS
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR-----GPYESGSGHSSGLGHRESRS 2467
Query: 602 RSDIDVNAAAGAKAHHA---------------------AGQSVRSGRLGAGALNAGSYAS 640
+ H + +GQS G+ G+G+ + Y
Sbjct: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2527
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
S + G R S G G+ ++ S G+ + + S G S G+
Sbjct: 2528 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ- 2586
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQG 760
+S+ +Q S S G + S S +SSR R S G
Sbjct: 2587 ------------------SSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERHGSSSG 2624
Query: 761 CSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKK 820
S + S S Q G G S S + S L S + + + +
Sbjct: 2625 SSSHYGQHGS------GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 2678
Query: 821 PARRRYES-------YGMHSDDDANSDASSA--------CSERSYSSRNGSIPTYMRQTE 865
+R YES +G H +S A S CS+ + S +G T+ ++
Sbjct: 2679 SSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 2738
Query: 866 DVAEVLNRCASSNWSERKEG 885
+ SS++ R G
Sbjct: 2739 STGQ------SSSYGHRGSG 2752
Score = 37.0 bits (84), Expect = 0.14
Identities = 71/295 (24%), Positives = 111/295 (37%), Gaps = 26/295 (8%)
Query: 553 SDRSSSSSQESLNRPFSSKW----STANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVN 608
S +SSS Q + SS S ++ S+ GR +GS ++ PG QR
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---PGHGQRGSGSRQ-- 2547
Query: 609 AAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAG 668
+ + + +G+S SG+ G+G + + E +S + + S+ G +G
Sbjct: 2548 SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ-SSSYSQHG----------SG 2596
Query: 669 MGNAKADSRGRSRTKMVSQSQP-GSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRS 727
G++ + SR+ S+ + GS SGS + S SSG R S S Q S
Sbjct: 2597 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ--GSGSGQSPS 2654
Query: 728 KIPRSQGCSREASPSRL---SVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGP 784
+ G +S + S SSR P S S ES S S G
Sbjct: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
Query: 785 GYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANS 839
G+ SQ S+S + GS ++ + + + YG H S
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 2769
Score = 36.2 bits (82), Expect = 0.25
Identities = 80/380 (21%), Positives = 123/380 (32%), Gaps = 78/380 (20%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPF--SSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
SG S + S S Q S P+ S WS++ G +GS +S L RS
Sbjct: 1003 SGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSR-----GPYESGSGHSSGLGHRESRS 1057
Query: 602 RSDIDVNAAAGAKAHHA---------------------AGQSVRSGRLGAGALNAGSYAS 640
+ H + +GQS G+ G+G+ + Y
Sbjct: 1058 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 1117
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
S + G R S G G+ ++ S G+ + + S G S G+
Sbjct: 1118 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ- 1176
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQG 760
+S+ +Q S S G + S S +SSR R S G
Sbjct: 1177 ------------------SSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERHGSSSG 1214
Query: 761 CSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKK 820
S + S S Q G G S S S L S + + + +
Sbjct: 1215 SSSHYGQHGS------GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268
Query: 821 PARRRYES-------YGMHSDDDANSDASSA--------CSERSYSSRNGSIPTYMRQTE 865
+R YES +G H +S A S CS+ + S +G T+ ++
Sbjct: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1328
Query: 866 DVAEVLNRCASSNWSERKEG 885
+ SS++ R G
Sbjct: 1329 STGQ------SSSYGHRGSG 1342
Score = 35.8 bits (81), Expect = 0.32
Identities = 74/333 (22%), Positives = 111/333 (33%), Gaps = 41/333 (12%)
Query: 544 SGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVS-AGSSKASSLPGSLQRSR 602
SGS S S S S P+ S + + S + R S +G S GS
Sbjct: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYES--GSGHSSGLGHRESRSGQSSGYGQHGSSSGHS 2013
Query: 603 SDIDVNAAAGAKA----HHAA--GQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDG 656
S + +A ++ H A GQS G+ G+G+ + Y S + G
Sbjct: 2014 STHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2073
Query: 657 RVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRV 716
R S G G+ ++ S G+ + S G S G+
Sbjct: 2074 GSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQ----------------- 2116
Query: 717 LVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQG-CSREASRESSRDTSP 775
+S+ +Q S S G + S S +SSR R S G SR S S
Sbjct: 2117 --SSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERHGSSSGSSSRYGQHGSGSRQSS 2170
Query: 776 VRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDD 835
Q G G+ S+ S S + GS + + + +G H
Sbjct: 2171 GHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230
Query: 836 DANSDASSA--------CSERSYSSRNGSIPTY 860
+S A S CS+ + S +G T+
Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 2263
Score = 35.0 bits (79), Expect = 0.55
Identities = 74/336 (22%), Positives = 116/336 (34%), Gaps = 56/336 (16%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASS-----LPGS 597
S+GS +S Q S S++SL S +PS GR +GS ++SS
Sbjct: 510 SAGSSSSYGQH---GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566
Query: 598 LQRSRSDIDVNAAAGAKAHH---AAGQSVRSGRLGAGALNAGSYASLEDTSDK------- 647
SR + + + H +GQS G+ G+ + ++ ++ TS +
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626
Query: 648 --LDGTASEDGRVRAKLSAP----LAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVL 701
G +S G+ + S G G+ ++ SRGR + S G G
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS 686
Query: 702 TTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGC 761
+ +VS S+ +S +S G S+ S S S S G
Sbjct: 687 SNGPHGSVSG-------QSSGFGHKSGSGQSSGYSQHGSGS-------------SHSSGY 726
Query: 762 SREASRESSRDTSPVR-SFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKK 820
+ SR S S L YG S SS + +G
Sbjct: 727 RKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-----------HS 775
Query: 821 PARRRYESYGMHSDDDANSDASSACSERSYSSRNGS 856
P+R R+ S HS + ++CS +GS
Sbjct: 776 PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGS 811
Score = 31.2 bits (69), Expect = 7.9
Identities = 43/175 (24%), Positives = 65/175 (37%), Gaps = 29/175 (16%)
Query: 477 QTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKS 536
Q+ S RH + L + G H + + R +R Y H +++ E S
Sbjct: 2651 QSPSRGRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRLGH-----SSVFGQHESGSGHS 2704
Query: 537 LQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPG 596
SGS Q S+S Q S F + S+ S+ G +GSS++S
Sbjct: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSST---FDQEGSSTGQSSSYGHRGSGSSQSS---- 2757
Query: 597 SLQRSRSDIDVNAAAGAKAHHA-AGQSVRSGRLGAGALNAGSYASLEDTSDKLDG 650
G H A +GQS+ GR G+G+ + SY S + G
Sbjct: 2758 ---------------GYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSG 2797
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 42.4 bits (98), Expect = 0.003
Identities = 54/217 (24%), Positives = 93/217 (42%), Gaps = 14/217 (6%)
Query: 590 KASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLD 649
KA S PGSL + + + + +K +S+R GR A A S +S +S
Sbjct: 1007 KAPSHPGSLAK-KPESTTKRSPSSKGTSEPEKSLRKGR-PALASQESSLSSTSPSSPLPV 1064
Query: 650 GTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTV 709
+ + R R+K + G G + + + + + +SQ S SP + + +AL+
Sbjct: 1065 KVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQKQKSASALTYT 1124
Query: 710 SSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRES 769
+S + + RS P + + + S SR SR S G R ++ +
Sbjct: 1125 ASSTSAKKASGPAT--RSPFPPGKSRTSDHSLSR----EGSR-----QSLGSDRASATST 1173
Query: 770 SRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNT 806
S+ SP S G G G + R SSS++++R +T
Sbjct: 1174 SKPNSPRVSQARAGEGRGAGKHVR-SSSMASLRSPST 1209
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 41.6 bits (96), Expect = 0.006
Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 57/323 (17%)
Query: 582 GRVSAGSSKASSLPGSLQRSRSDIDVNA--------AAGAKAHHAAGQSVR---SGRLG- 629
G VSAG + +SS S +D++V A AA A A G+ G+ G
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGA 248
Query: 630 ------AGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTK 683
AG S +S E++SD + T + ++AK S + +G A A ++ S K
Sbjct: 249 VASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRK 307
Query: 684 MVSQSQPG------SRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSR 737
+ + PG +++ + R + + S S + A A+ K P+ + S
Sbjct: 308 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA---PAQAKPSGKAPQVRAASA 364
Query: 738 EA--SPSRLSVARSSRIPRPSVSQ---GCSREASRESSRDTSPVR---------SFQPLG 783
A SP + + R P+ +Q G E SR SS ++ R +PLG
Sbjct: 365 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 424
Query: 784 PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASS 843
+ +S + M L G+ V PA + D +++S+ SS
Sbjct: 425 KSPQVKPASTM-----GMGPLGKGAG---PVPPGKVGPATPSAQVGKWEEDSESSSEESS 476
Query: 844 ACSERSYSSRNGSIPTYMRQTED 866
S +G +PT + ++
Sbjct: 477 -------DSSDGEVPTAVAPAQE 492
Score = 34.7 bits (78), Expect = 0.71
Identities = 76/327 (23%), Positives = 112/327 (34%), Gaps = 46/327 (14%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
K+ S A + D S SSS+E S G A + A + L
Sbjct: 841 KTGPSAAQAGKQDDSGSSSEE---------------SDSDGEAPAAVTSAQVIKPPL--- 882
Query: 602 RSDIDVN-AAAGAKAHHAAGQSVRSGRLG-AGALNAGSYASLEDTSDKLDGTASEDGRVR 659
+D N + AG A A Q+ + R A A S +S + D + T +R
Sbjct: 883 -IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 941
Query: 660 AKL------------SAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALS 707
+ A +AG ++K SR K + S+ LT AL
Sbjct: 942 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1001
Query: 708 TVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSV----ARSSRIPR-PSVSQGCS 762
++ A Q S + + G SP SV R P+ P V Q
Sbjct: 1002 VLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK 1061
Query: 763 REASRESSRDTSPVRS-FQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVA----DA 817
S + S D+S S + G G Q ++ + ++ T + VEE A D
Sbjct: 1062 APESSDDSEDSSDSSSGSEEDGEG---PQGAKSAHTLVGPTPSRTETLVEETAAESSEDD 1118
Query: 818 LKKPARRRYESYGMHSDDDANSDASSA 844
+ P++ Y ANS AS A
Sbjct: 1119 VVAPSQSLLSGYMTPGLTPANSQASKA 1145
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 41.6 bits (96), Expect = 0.006
Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 57/323 (17%)
Query: 582 GRVSAGSSKASSLPGSLQRSRSDIDVNA--------AAGAKAHHAAGQSVR---SGRLG- 629
G VSAG + +SS S +D++V A AA A A G+ G+ G
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGA 248
Query: 630 ------AGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTK 683
AG S +S E++SD + T + ++AK S + +G A A ++ S K
Sbjct: 249 VASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRK 307
Query: 684 MVSQSQPG------SRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSR 737
+ + PG +++ + R + + S S + A A+ K P+ + S
Sbjct: 308 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA---PAQAKPSGKAPQVRAASA 364
Query: 738 EA--SPSRLSVARSSRIPRPSVSQ---GCSREASRESSRDTSPVR---------SFQPLG 783
A SP + + R P+ +Q G E SR SS ++ R +PLG
Sbjct: 365 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 424
Query: 784 PGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASS 843
+ +S + M L G+ V PA + D +++S+ SS
Sbjct: 425 KSPQVKPASTM-----GMGPLGKGAG---PVPPGKVGPATPSAQVGKWEEDSESSSEESS 476
Query: 844 ACSERSYSSRNGSIPTYMRQTED 866
S +G +PT + ++
Sbjct: 477 -------DSSDGEVPTAVAPAQE 492
Score = 34.3 bits (77), Expect = 0.93
Identities = 75/324 (23%), Positives = 108/324 (33%), Gaps = 41/324 (12%)
Query: 542 KSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRS 601
K+ S A + D S SSS+E S G A + A + L
Sbjct: 841 KTGPSAAQAGKQDDSGSSSEE---------------SDSDGEAPAAVTSAQVIKPPL--- 882
Query: 602 RSDIDVN-AAAGAKAHHAAGQSVRSGRLG-AGALNAGSYASLEDTSDKLDGTASEDGRVR 659
+D N + AG A A Q+ + R A A S +S + D + T +R
Sbjct: 883 -IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 941
Query: 660 AKL------------SAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALS 707
+ A +AG ++K SR K + S+ LT AL
Sbjct: 942 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1001
Query: 708 TVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSV----ARSSRIPR-PSVSQGCS 762
++ A Q S + + G SP SV R P+ P V Q
Sbjct: 1002 VLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK 1061
Query: 763 REASRESSRDTSPVRS-FQPLGPG-YGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKK 820
S + S D+S S + G G G + L + S L E+ D +
Sbjct: 1062 APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETL-VEETAAESSEDDVVA 1120
Query: 821 PARRRYESYGMHSDDDANSDASSA 844
P++ Y ANS AS A
Sbjct: 1121 PSQSLLSGYMTPGLTPANSQASKA 1144
>gi|193083131 MAP/microtubule affinity-regulating kinase 3 isoform e
[Homo sapiens]
Length = 659
Score = 41.6 bits (96), Expect = 0.006
Identities = 50/208 (24%), Positives = 78/208 (37%), Gaps = 33/208 (15%)
Query: 585 SAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGR--------LGAGALNAG 636
++ SS +S+L SL + R D+N + G HH +SV S + G +
Sbjct: 294 ASDSSSSSNL--SLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVV 351
Query: 637 SYASLEDTSDKLDGTASEDGRVRAKLSAPLAG----------MGNAKADSRGRSRTKMVS 686
+Y TS D EDG K S G +GNA ++ + S
Sbjct: 352 AYPKRSQTSTA-DSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKS 410
Query: 687 QSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV------NSASAQKRSKIPRSQGCSREAS 740
+ P S + S G T + + + R V NS +R+ + + S A+
Sbjct: 411 STVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAAT 470
Query: 741 PSRLSVARSSRIPRPSVSQGCSREASRE 768
P R+ R PR + S+ RE
Sbjct: 471 PDRI------RFPRGTASRSTFHGQPRE 492
>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
[Homo sapiens]
Length = 744
Score = 41.6 bits (96), Expect = 0.006
Identities = 50/208 (24%), Positives = 78/208 (37%), Gaps = 33/208 (15%)
Query: 585 SAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGR--------LGAGALNAG 636
++ SS +S+L SL + R D+N + G HH +SV S + G +
Sbjct: 373 ASDSSSSSNL--SLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVV 430
Query: 637 SYASLEDTSDKLDGTASEDGRVRAKLSAPLAG----------MGNAKADSRGRSRTKMVS 686
+Y TS D EDG K S G +GNA ++ + S
Sbjct: 431 AYPKRSQTSTA-DSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKS 489
Query: 687 QSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV------NSASAQKRSKIPRSQGCSREAS 740
+ P S + S G T + + + R V NS +R+ + + S A+
Sbjct: 490 STVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAAT 549
Query: 741 PSRLSVARSSRIPRPSVSQGCSREASRE 768
P R+ R PR + S+ RE
Sbjct: 550 PDRI------RFPRGTASRSTFHGQPRE 571
>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
[Homo sapiens]
Length = 753
Score = 41.6 bits (96), Expect = 0.006
Identities = 50/208 (24%), Positives = 78/208 (37%), Gaps = 33/208 (15%)
Query: 585 SAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGR--------LGAGALNAG 636
++ SS +S+L SL + R D+N + G HH +SV S + G +
Sbjct: 373 ASDSSSSSNL--SLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVV 430
Query: 637 SYASLEDTSDKLDGTASEDGRVRAKLSAPLAG----------MGNAKADSRGRSRTKMVS 686
+Y TS D EDG K S G +GNA ++ + S
Sbjct: 431 AYPKRSQTSTA-DSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKS 489
Query: 687 QSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV------NSASAQKRSKIPRSQGCSREAS 740
+ P S + S G T + + + R V NS +R+ + + S A+
Sbjct: 490 STVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAAT 549
Query: 741 PSRLSVARSSRIPRPSVSQGCSREASRE 768
P R+ R PR + S+ RE
Sbjct: 550 PDRI------RFPRGTASRSTFHGQPRE 571
>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
[Homo sapiens]
Length = 729
Score = 41.6 bits (96), Expect = 0.006
Identities = 50/208 (24%), Positives = 78/208 (37%), Gaps = 33/208 (15%)
Query: 585 SAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGR--------LGAGALNAG 636
++ SS +S+L SL + R D+N + G HH +SV S + G +
Sbjct: 373 ASDSSSSSNL--SLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVV 430
Query: 637 SYASLEDTSDKLDGTASEDGRVRAKLSAPLAG----------MGNAKADSRGRSRTKMVS 686
+Y TS D EDG K S G +GNA ++ + S
Sbjct: 431 AYPKRSQTS-TADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKS 489
Query: 687 QSQPGSRSGSPGRVLTTTALSTVSSGVQRVLV------NSASAQKRSKIPRSQGCSREAS 740
+ P S + S G T + + + R V NS +R+ + + S A+
Sbjct: 490 STVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAAT 549
Query: 741 PSRLSVARSSRIPRPSVSQGCSREASRE 768
P R+ R PR + S+ RE
Sbjct: 550 PDRI------RFPRGTASRSTFHGQPRE 571
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 40.4 bits (93), Expect = 0.013
Identities = 44/210 (20%), Positives = 94/210 (44%), Gaps = 21/210 (10%)
Query: 1272 VAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIR 1331
++ LL+++++ ++ + R +A +LM Q++S + ++ + ++ +LL L DK ++
Sbjct: 8 ISSLLEKMTSSDK--DFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ 65
Query: 1332 ALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRS--------------AEE 1377
LA+K L ++ + K Y T++ TL + KE +R
Sbjct: 66 NLAVKCLGPLV----VKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAA 121
Query: 1378 AASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGL 1437
S LAT++ + ++ I Q D + L A+ + + ++ R+ L ++ L
Sbjct: 122 TGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLG-VPLGAFHASLLHCL 180
Query: 1438 IQGYDNSESSVRKACVFCLVAVHAVIGDEL 1467
+ + +VRK V L + A +L
Sbjct: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDL 210
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 40.0 bits (92), Expect = 0.017
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 56/302 (18%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL---- 598
S+GS+ + P + +SS S SK T PS V G+ A SS+A+S G
Sbjct: 1645 SAGSITASPGASATSSES---------SKSGTTGPS-VGGKTGATSSEATSSEGMSGVTG 1694
Query: 599 ----QRSRSDIDVNAAAGAKAHHAAGQSVRS-----GRLGAGALNAGSYASLEDTSDKLD 649
+ SD ++ A G+ R G G G+ A+ +
Sbjct: 1695 QSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTS 1754
Query: 650 GT-ASEDGRVRAKLSAP------LAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLT 702
G S +G V A SA +G G+ + S T +VS PG+ G+PG
Sbjct: 1755 GALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVS---PGATPGAPG---- 1807
Query: 703 TTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCS 762
SS + + S K K S S + L+ A R P S + S
Sbjct: 1808 -------SSTPGEADIGNTSFGKSGK-------SGHDSLTVLNPAFLRRTPTVSAASTTS 1853
Query: 763 REASRESSRDTSPVRSFQPLGPGY-----GISQSSRLSSSVSAMRVLNTGSDVEEAVADA 817
S+ + ++ + PG G + +++S S+ S+ ++ A
Sbjct: 1854 SPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGSSNTPGEISKA 1913
Query: 818 LK 819
LK
Sbjct: 1914 LK 1915
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 40.0 bits (92), Expect = 0.017
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 56/302 (18%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL---- 598
S+GS+ + P + +SS S SK T PS V G+ A SS+A+S G
Sbjct: 1829 SAGSITASPGASATSSES---------SKSGTTGPS-VGGKTGATSSEATSSEGMSGVTG 1878
Query: 599 ----QRSRSDIDVNAAAGAKAHHAAGQSVRS-----GRLGAGALNAGSYASLEDTSDKLD 649
+ SD ++ A G+ R G G G+ A+ +
Sbjct: 1879 QSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTS 1938
Query: 650 GT-ASEDGRVRAKLSAP------LAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLT 702
G S +G V A SA +G G+ + S T +VS PG+ G+PG
Sbjct: 1939 GALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVS---PGATPGAPG---- 1991
Query: 703 TTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCS 762
SS + + S K K S S + L+ A R P S + S
Sbjct: 1992 -------SSTPGEADIGNTSFGKSGK-------SGHDSLTVLNPAFLRRTPTVSAASTTS 2037
Query: 763 REASRESSRDTSPVRSFQPLGPGY-----GISQSSRLSSSVSAMRVLNTGSDVEEAVADA 817
S+ + ++ + PG G + +++S S+ S+ ++ A
Sbjct: 2038 SPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGSSNTPGEISKA 2097
Query: 818 LK 819
LK
Sbjct: 2098 LK 2099
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 40.0 bits (92), Expect = 0.017
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 56/302 (18%)
Query: 543 SSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL---- 598
S+GS+ + P + +SS S SK T PS V G+ A SS+A+S G
Sbjct: 1829 SAGSITASPGASATSSES---------SKSGTTGPS-VGGKTGATSSEATSSEGMSGVTG 1878
Query: 599 ----QRSRSDIDVNAAAGAKAHHAAGQSVRS-----GRLGAGALNAGSYASLEDTSDKLD 649
+ SD ++ A G+ R G G G+ A+ +
Sbjct: 1879 QSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTS 1938
Query: 650 GT-ASEDGRVRAKLSAP------LAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLT 702
G S +G V A SA +G G+ + S T +VS PG+ G+PG
Sbjct: 1939 GALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVS---PGATPGAPG---- 1991
Query: 703 TTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCS 762
SS + + S K K S S + L+ A R P S + S
Sbjct: 1992 -------SSTPGEADIGNTSFGKSGK-------SGHDSLTVLNPAFLRRTPTVSAASTTS 2037
Query: 763 REASRESSRDTSPVRSFQPLGPGY-----GISQSSRLSSSVSAMRVLNTGSDVEEAVADA 817
S+ + ++ + PG G + +++S S+ S+ ++ A
Sbjct: 2038 SPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGASNTPGEISKA 2097
Query: 818 LK 819
LK
Sbjct: 2098 LK 2099
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 40.0 bits (92), Expect = 0.017
Identities = 69/293 (23%), Positives = 104/293 (35%), Gaps = 51/293 (17%)
Query: 539 TYLKSSGSVASL--PQSDRSSSSSQESLNRPFSSKWSTAN-PSTVAGRVSAGSSKASSLP 595
TY S GS ++ P+SD +S +ES S+ + ++ PST + V +S SS P
Sbjct: 831 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS-P 889
Query: 596 GSL-------QRSRSDIDVNAAAGAKAHHAAG------QSVRSGRLGAGALNAGSYASLE 642
GS + S + A + A G +S S LG + S S+E
Sbjct: 890 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 949
Query: 643 DT----SDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGS------ 692
T S G + + +P + A S G S S+S+PGS
Sbjct: 950 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009
Query: 693 ---------------RSGSPGRVLTT-TALSTVSSGVQRVLVNSASAQKRSKIPRSQGCS 736
SPG TT ST +SG + S S+ + S G +
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 1069
Query: 737 REASPSRLSV--------ARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQP 781
S + S ++ P + S G ++R S SP + P
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 1122
Score = 37.0 bits (84), Expect = 0.14
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 39/361 (10%)
Query: 531 PSYQKSLQTYLKSSGSVASL--PQSDRSSSSSQESL---NRPFSSKWSTANPSTVAGRVS 585
P + T+ S S A+ P S SS S+ES +RP S+ + ST +S
Sbjct: 3600 PGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 3659
Query: 586 AGSSKASSLPGSLQRSRSDIDVNAAAGAK----AHHAAGQSVRSGRLGA-GALNAG---- 636
S+ + S PGS + + ++ +H ++G + + G+ AL+ G
Sbjct: 3660 RHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 3719
Query: 637 --------SYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQS 688
++ +L S G RV + +P + A + S G Q+
Sbjct: 3720 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 3779
Query: 689 QPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRL---S 745
P S +P T TA S+ R S + + P S S + S + S
Sbjct: 3780 HPASTHTTPSPPSTATAPVEESTTYHR----SPGSTPTTHFPASSTTSGHSEKSTIFHSS 3835
Query: 746 VARSSRIPRP--SVSQGCSREASRESSRDTSPVRSF--QPLGPGYGISQSSRLSSSVSAM 801
S P S + G + S ++ + + PG + ++ SS S
Sbjct: 3836 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 3895
Query: 802 RVLNTGSDVEEAVADALKKPARRRYESYGMHSDDDANSDASSACSERS---YSSRNGSIP 858
L+ S V + + R + HS S + SE S YSS GS
Sbjct: 3896 TTLSPASMTSLGVGE---ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 3952
Query: 859 T 859
T
Sbjct: 3953 T 3953
Score = 36.6 bits (83), Expect = 0.19
Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 27/251 (10%)
Query: 527 NSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSA 586
+S P Q T+ S + P ++++ E S ST A ++
Sbjct: 2681 SSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 2740
Query: 587 GSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSD 646
G S+ S++ S D + + AH S SGR G + S S E T+
Sbjct: 2741 GHSEKSTI------FHSSPDASGTTPSSAH-----STTSGR-GESTTSRISPGSTEITT- 2787
Query: 647 KLDGTASEDGRVRAKLS------APLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
L G+ + G A + +P + A S G S+SQPGS +
Sbjct: 2788 -LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCS-REASP----SRLSVARSSRIPRP 755
TTT +S V +S + + + PRS S R P SR + ++
Sbjct: 2847 STTT--PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTED 2904
Query: 756 SVSQGCSREAS 766
S + G + E++
Sbjct: 2905 STTSGLTEEST 2915
Score = 35.8 bits (81), Expect = 0.32
Identities = 77/356 (21%), Positives = 126/356 (35%), Gaps = 37/356 (10%)
Query: 521 EAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTV 580
E T + S S +L +S V+ + S S + P S+ + +
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748
Query: 581 AGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYAS 640
A S GS+ + PGS S + + H++ S + +
Sbjct: 1749 ASHSSPGSTDTTLSPGSTTAS------SLGPESTTFHSSPGSTET--------------T 1788
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSR-GRSRTKMVSQSQPGSRSGSPGR 699
L + G V + +P + A + +R G S T QS P S+ P
Sbjct: 1789 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT---FQSWPSSKDTMPAP 1845
Query: 700 VLTTTA---LSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRP- 755
TT+A LST S G +S S + G S E++ S ++ P P
Sbjct: 1846 PTTTSAFVELSTTSHGSP----SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 1901
Query: 756 -SVSQGCSREASR-ESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEA 813
S + G E++ SS ++ F G S+ SR S S S +++ A
Sbjct: 1902 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHS-STTHTISSPPSTTSA 1960
Query: 814 VADALKKPARRRYESYGMHSDDDANSDASSACSERSYSSRN--GSIPTYMRQTEDV 867
+ + + H D + + S S S+SS++ G+I R T V
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 2016
Score = 35.4 bits (80), Expect = 0.42
Identities = 57/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 527 NSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSA 586
+S P Q + S + P ++++ E S ST A ++
Sbjct: 3764 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 3823
Query: 587 GSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSD 646
G S+ S++ S D + + AH S SGR G + S S E T+
Sbjct: 3824 GHSEKSTI------FHSSPDASGTTPSSAH-----STTSGR-GESTTSRISPGSTEITT- 3870
Query: 647 KLDGTASEDGRVRAKLS------APLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
L G+ + G A + +P + A S G S+SQPGS +
Sbjct: 3871 -LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCS-REASP----SRLSVARSSRIPRP 755
TTT +S V +S + + + PRS S R P SR + ++
Sbjct: 3930 STTT--PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTED 3987
Query: 756 SVSQGCSREAS 766
S + G + E++
Sbjct: 3988 STTSGLTEEST 3998
Score = 33.9 bits (76), Expect = 1.2
Identities = 54/260 (20%), Positives = 96/260 (36%), Gaps = 28/260 (10%)
Query: 521 EAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNR---PFSSKWSTANP 577
E T Y+S S + T+ S + + + +S SSQ++ P S S
Sbjct: 4603 EEPTSYHSSPGS---TATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 4659
Query: 578 STVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGS 637
+ +S+GS + ++LPGS + + H++ S + A + G
Sbjct: 4660 ESTTSPISSGSMETTALPGSTTTP------GLSEKSTTFHSSPSSTPTTHFSASSTTLGR 4713
Query: 638 YASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSP 697
TA+ R+ S L A S G ++T +S S
Sbjct: 4714 SEESTTVHSSPVATATTPSPARSTTSG-LVEESTAYHSSPGSTQTMHFPESSTASGRSEE 4772
Query: 698 GRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSV 757
R ++ T+SS SA ++ + S +SP ++ ++ P S
Sbjct: 4773 SRTSHSSTTHTISSPPS---TTSALVEEPT--------SYHSSPGSIA---TTHFPESST 4818
Query: 758 SQGCSREA-SRESSRDTSPV 776
+ G S E+ + SS DT+ +
Sbjct: 4819 TSGRSEESTASHSSPDTNGI 4838
Score = 33.5 bits (75), Expect = 1.6
Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 527 NSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSA 586
+S P Q + S + P ++++ E S ST A ++
Sbjct: 2207 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 2266
Query: 587 GSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSD 646
G S+ S++ S D + + AH S SGR G + S S E T+
Sbjct: 2267 GHSEKSTI------FHSSPDASGTTPSSAH-----STTSGR-GESTTSRISPGSTEITT- 2313
Query: 647 KLDGTASEDGRVRAKLS------APLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
L G+ + G A + +P + A S G S+SQPGS +
Sbjct: 2314 -LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372
Query: 701 LTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCS-REASP----SRLSVARSSRIPRP 755
TTT +S V +S + + + PR+ S R P SR + ++
Sbjct: 2373 STTT--PGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED 2430
Query: 756 SVSQGCSREAS 766
S + G + E++
Sbjct: 2431 STTSGLTEEST 2441
Score = 33.5 bits (75), Expect = 1.6
Identities = 75/356 (21%), Positives = 125/356 (35%), Gaps = 37/356 (10%)
Query: 521 EAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTV 580
E T + S S +L +S V+ + S S + P S+ + +
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQEST 4388
Query: 581 AGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYAS 640
A S GS+ + PGS S + + H++ S + +
Sbjct: 4389 ASHSSPGSTDTTLSPGSTTAS------SLGPESTTFHSSPGSTET--------------T 4428
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSR-GRSRTKMVSQSQPGSRSGSPGR 699
L + G V + +P + A + +R G S T QS P S+ +P
Sbjct: 4429 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT---FQSWPNSKDTTPAP 4485
Query: 700 VLTTTA---LSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRP- 755
TT+A LST S G +S S + G S E++ S ++ P P
Sbjct: 4486 PTTTSAFVELSTTSHGSP----SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 4541
Query: 756 -SVSQGCSREASR-ESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEA 813
S + G E++ SS ++ F G + S S S S +++ A
Sbjct: 4542 RSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHS-STTHTISSAPSTTSA 4600
Query: 814 VADALKKPARRRYESYGMHSDDDANSDASSACSERSYSSRN--GSIPTYMRQTEDV 867
+ + + H D + + S S S+SS++ G+I R T V
Sbjct: 4601 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 4656
Score = 33.1 bits (74), Expect = 2.1
Identities = 76/356 (21%), Positives = 125/356 (35%), Gaps = 37/356 (10%)
Query: 521 EAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTV 580
E T + S S +L +S V+ + S S + P S+ + +
Sbjct: 3246 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 3305
Query: 581 AGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYAS 640
A S GS+ + PGS S + G + G G+ + +
Sbjct: 3306 ASHSSPGSTDTTLSPGSTTAS----------------SLGPESTTFHSGPGS----TETT 3345
Query: 641 LEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSR-GRSRTKMVSQSQPGSRSGSPGR 699
L + G V + +P + A + +R G S T QS P S+ +P
Sbjct: 3346 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT---FQSWPNSKDTTPAP 3402
Query: 700 VLTTTA---LSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRP- 755
TT+A LST S G +S S + G S E++ S ++ P P
Sbjct: 3403 PTTTSAFVELSTTSHGSP----SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 3458
Query: 756 -SVSQGCSREASR-ESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEA 813
S + G E++ SS ++ F G + S S S S +++ A
Sbjct: 3459 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS-STTHTISSAPSTTSA 3517
Query: 814 VADALKKPARRRYESYGMHSDDDANSDASSACSERSYSSRN--GSIPTYMRQTEDV 867
+ + + H D + + S S S+SS++ G+I R T V
Sbjct: 3518 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 3573
Score = 32.3 bits (72), Expect = 3.5
Identities = 43/184 (23%), Positives = 66/184 (35%), Gaps = 20/184 (10%)
Query: 527 NSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSA 586
+S P Q + S + P ++++ E S ST A ++
Sbjct: 1124 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 1183
Query: 587 GSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSD 646
G S+ S++ S D + + AH S SGR G + S S E T+
Sbjct: 1184 GHSEKSTI------FHSSPDASGTTPSSAH-----STTSGR-GESTTSRISPGSTEITT- 1230
Query: 647 KLDGTASEDGRVRAKLS------APLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRV 700
L G+ + G A + +P + A S G S+SQPGS +
Sbjct: 1231 -LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289
Query: 701 LTTT 704
TTT
Sbjct: 1290 STTT 1293
Score = 32.3 bits (72), Expect = 3.5
Identities = 59/232 (25%), Positives = 90/232 (38%), Gaps = 35/232 (15%)
Query: 534 QKSLQTYLKSSGSVAS--LPQSDRSSSSSQESL---NRPFSSKW------STANPSTVAG 582
++S Y S GS + P+S +S +E +RP S+ ST + T
Sbjct: 3938 EESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEES 3997
Query: 583 RVSAGS--SKASSLPGSL------QRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALN 634
GS S + LP +L + S + + + G K A +S SG +G +
Sbjct: 3998 TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPA--RSTTSGLVGESTPS 4055
Query: 635 AGSYASLEDT----SDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQP 690
S +S E T S + + +P A + A S G S S SQP
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP 4115
Query: 691 GSRSGSPGRVLTTTAL--STVSSGVQRVLVNSASAQKRSKIPRSQGCSREAS 740
GS TTA ST +SG+ + S S+Q ++ S G + +S
Sbjct: 4116 GSTH--------TTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159
Score = 31.2 bits (69), Expect = 7.9
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 19/200 (9%)
Query: 521 EAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNR---PFSSKWSTANP 577
E T Y+S S + T+ S + + + +S SSQ++ P S S
Sbjct: 1963 EEPTSYHSSPGS---TATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 2019
Query: 578 STVAGRVSAGSSKASSLPGSLQR---SRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALN 634
+ +S+GS + ++LPGS S +++ + A + S S + +
Sbjct: 2020 ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTT 2079
Query: 635 AGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGN-----AKADSRGRSRTKMVSQSQ 689
+ S T+ D T + + S G + A + G S+ S S
Sbjct: 2080 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2139
Query: 690 PGSRSG--SPGRVLTTTALS 707
PGS SPG +TTALS
Sbjct: 2140 PGSTDTALSPG---STTALS 2156
Score = 31.2 bits (69), Expect = 7.9
Identities = 52/230 (22%), Positives = 87/230 (37%), Gaps = 31/230 (13%)
Query: 534 QKSLQTYLKSSGSVAS--LPQSDRSSSSSQESL---NRPFSSKWSTANPSTVAGRVSAGS 588
++S Y S GS + P+S +S +E +RP S+ + + ++ S
Sbjct: 2855 EESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 2914
Query: 589 SKASSLPGSLQR------SRSDIDVNAAAGAKAHHAAG------QSVRSGRLGAGALNAG 636
+ P S Q + +D+ + + + G +S SG +G +
Sbjct: 2915 TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL 2974
Query: 637 SYASLEDT----SDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGS 692
S +S E T S + + +P A + A S G S S SQPGS
Sbjct: 2975 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 3034
Query: 693 RSGSPGRVLTTTAL--STVSSGVQRVLVNSASAQKRSKIPRSQGCSREAS 740
TTA ST +SG+ + S S+Q ++ S G + +S
Sbjct: 3035 TH--------TTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASS 3076
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,603,141
Number of Sequences: 37866
Number of extensions: 2439967
Number of successful extensions: 12831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 11811
Number of HSP's gapped (non-prelim): 1069
length of query: 1506
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1391
effective length of database: 13,892,928
effective search space: 19325062848
effective search space used: 19325062848
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.