Guide to the Human Genome
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Search of human proteins with 5729781

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729781 complexin 1 [Homo sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729781 complexin 1 [Homo sapiens]                                 265   6e-72
gi|56550065 complexin 2 [Homo sapiens]                                228   1e-60
gi|5729783 complexin 2 [Homo sapiens]                                 228   1e-60
gi|71725345 complexin 3 [Homo sapiens]                                 59   9e-10
gi|31795561 complexin 4 [Homo sapiens]                                 49   2e-06
gi|148746183 ubiquitin specific protease 35 [Homo sapiens]             47   6e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     42   2e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    42   2e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            41   3e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                40   7e-04
gi|148746195 trichohyalin [Homo sapiens]                               40   7e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        39   0.001
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s...    39   0.002
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    39   0.002
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            38   0.002
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    38   0.002
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    38   0.002
gi|221219020 NYD-SP11 protein [Homo sapiens]                           38   0.003
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    38   0.003
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              38   0.003
gi|55741655 anoctamin 8 [Homo sapiens]                                 37   0.004
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    37   0.004
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    37   0.004
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    37   0.004
gi|13027602 DDRGK domain containing 1 [Homo sapiens]                   37   0.004
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    37   0.004
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    37   0.004
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    37   0.005
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    37   0.005
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]    37   0.005

>gi|5729781 complexin 1 [Homo sapiens]
          Length = 134

 Score =  265 bits (678), Expect = 6e-72
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60
           MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE
Sbjct: 1   MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60

Query: 61  AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
           AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV
Sbjct: 61  AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120

Query: 121 IKYLPGPLQDMLKK 134
           IKYLPGPLQDMLKK
Sbjct: 121 IKYLPGPLQDMLKK 134


>gi|56550065 complexin 2 [Homo sapiens]
          Length = 134

 Score =  228 bits (581), Expect = 1e-60
 Identities = 113/134 (84%), Positives = 123/134 (91%)

Query: 1   MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60
           M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE
Sbjct: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60

Query: 61  AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
            VRQ IRDKYG+KKKEE+EAE +AA+E   EGSLTRPKKAIP GCGDE EEE+ESILDTV
Sbjct: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120

Query: 121 IKYLPGPLQDMLKK 134
           +KYLPGPLQDM KK
Sbjct: 121 LKYLPGPLQDMFKK 134


>gi|5729783 complexin 2 [Homo sapiens]
          Length = 134

 Score =  228 bits (581), Expect = 1e-60
 Identities = 113/134 (84%), Positives = 123/134 (91%)

Query: 1   MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60
           M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE
Sbjct: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60

Query: 61  AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
            VRQ IRDKYG+KKKEE+EAE +AA+E   EGSLTRPKKAIP GCGDE EEE+ESILDTV
Sbjct: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120

Query: 121 IKYLPGPLQDMLKK 134
           +KYLPGPLQDM KK
Sbjct: 121 LKYLPGPLQDMFKK 134


>gi|71725345 complexin 3 [Homo sapiens]
          Length = 158

 Score = 59.3 bits (142), Expect = 9e-10
 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 15/136 (11%)

Query: 1   MEFVMKQALGGATKDMGKMLGGDEEK---DPDAAKKE-------EERQEALRQAEEERKA 50
           M F++K  +GG  K++   LGG E+K   D  AA+ +       EE Q+ L + + ER A
Sbjct: 1   MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60

Query: 51  KYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVE 110
           ++ + +AER  +R   RDKY + K E  E++ Q A      G +  P++       D  E
Sbjct: 61  QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115

Query: 111 EEDESILDTVIKYLPG 126
           EE+++ +   +  LPG
Sbjct: 116 EEEKASVLGQLASLPG 131


>gi|31795561 complexin 4 [Homo sapiens]
          Length = 160

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 16/145 (11%)

Query: 1   MEFVMKQALGGATKDMGKMLGGDEEK------DPDAAK-----KEEERQEALRQAEEERK 49
           M F+MK  +    K++G   G +E K      DP AA+     + EE Q+ + + + ER 
Sbjct: 1   MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERD 60

Query: 50  AKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEV 109
           A + + +AER  +R  +R+KY + K E  E + Q A +      +  P+        D+ 
Sbjct: 61  AAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGD-----DVDLPEDLRKMVDEDQE 115

Query: 110 EEEDESILDTVIKYLPGPLQDMLKK 134
           EEED+  +   I+ L     D +K+
Sbjct: 116 EEEDKDSILGQIQNLQNMDLDTIKE 140


>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
          Length = 1018

 Score = 46.6 bits (109), Expect = 6e-06
 Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 8/110 (7%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           K  GG   ++    ++EE ++E   + E   + +  + E ERE   +   ++  ++K+ E
Sbjct: 665 KEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETE 724

Query: 78  REAEAQAAMEANSEGSLTRPKKAIPPG---CGDEVEEEDESILDTVIKYL 124
           +EAE +   E +S G+ T P  AIP G   CG    E   S+LD V  +L
Sbjct: 725 KEAEQE--KEEDSLGAGTHPDAAIPSGERTCG---SEGSRSVLDLVNYFL 769


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 28/95 (29%), Positives = 48/95 (50%), Gaps = 6/95 (6%)

Query: 23  DEEKDPDAAKKEEERQEALRQ---AEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79
           +EE + +    E+E QEA R    ++++RK   A  +  +E   + ++ +  +KKKEE+E
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394

Query: 80  AEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
            E +  M+   E    R K       G+  +EEDE
Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEE---GESKDEEDE 426



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)

Query: 13  TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72
           +KD  K +   +++  +  ++E +++E +++ EE       K E E E ++Q   ++  I
Sbjct: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE-------KEEEEEEEMKQK-EEEEEI 410

Query: 73  KKKEEREAEAQAAMEANSE-GSLTRPKKAIPPGCGDEVEEEDESILD 118
           + K E E E++   + + + G     +    PG  +   E +E  LD
Sbjct: 411 RNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLD 457


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 28/118 (23%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE--- 79
           +E++  + A+ E+E QE L++ +EE +A+ ++ EAER+ +    R+K+  ++++ER+   
Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEAR-SREEAERQRLE---REKHFQQQEQERQERR 709

Query: 80  ------------------AEAQAAMEANSEGSLTRPKKAI---PPGCGDEVEEEDESI 116
                              + Q + EAN+ GS   P KA+    PG   E  +++E I
Sbjct: 710 KRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPI 767



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 31  AKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90
           A+++ ER+E  R+ + ER  +  + +  REA  +  R+    +++EE+EA  +A  E   
Sbjct: 610 AREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA-RRREEQEAREKAQAEQEE 668

Query: 91  EGSLTRPKKAIPPGCGDEVEEE 112
           +  L + K+       +E E +
Sbjct: 669 QERLQKQKEEAEARSREEAERQ 690



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%)

Query: 36  ERQEALRQ-AEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90
           +R+EA R  AE+ R+A+  +   E+E   Q  RDK   +++  REAEA+A  EA +
Sbjct: 595 DREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA 650


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 12/78 (15%)

Query: 22  GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           G +E++ +  K+  ER++  R+ E+ERK +            +G ++K G +KKEERE +
Sbjct: 51  GKKERESERKKERREREKRKREREKERKRE------------RGKKEKKGERKKEERERK 98

Query: 82  AQAAMEANSEGSLTRPKK 99
            +   + N EG     +K
Sbjct: 99  KRRREKENKEGEEKEKRK 116



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 22  GDEEKDPDAAKKEEERQEALRQAE------EERKAKYAKMEAEREAVRQGIRDKYGIKKK 75
           G +EK  +  K+E ER++  R+ E      +E++ K  K E  R +     R++   +K+
Sbjct: 82  GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141

Query: 76  EEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           EER+   +   E   E      KK      G++ EE  E
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 17/69 (24%), Positives = 38/69 (55%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           E ++ +  K+E E++    + ++E+K +  K E ER+  R+   +K G +K++ ++ E +
Sbjct: 62  ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121

Query: 84  AAMEANSEG 92
                + EG
Sbjct: 122 ERGRTSKEG 130



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 6/68 (8%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           K+ G+     +E++    +K EER+E  R+ EE  K +  K   +RE      R + G K
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE------RKQVGEK 174

Query: 74  KKEEREAE 81
           ++E +E E
Sbjct: 175 EEERKEKE 182



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 24  EEKDPDAAKKEEERQEALR--QAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           EE++ +  +KE +++E  +  + EEERK K  K   +RE  R+  + +   K++ ER+ E
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211

Query: 82  AQAAMEANSE 91
            +   E   E
Sbjct: 212 RKKKEERKKE 221



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 19/68 (27%), Positives = 33/68 (48%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91
           K+ E ++E  R+  +ER+ K  + E ERE   +  R++  + +KEE   E +       E
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190

Query: 92  GSLTRPKK 99
            +    KK
Sbjct: 191 RNRKERKK 198



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 11/72 (15%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           K +G  EE+  +  +KE +++E  R  +E +K +  K   ER+  R         KKKEE
Sbjct: 169 KQVGEKEEERKEKERKERKKRE--RNRKERKKERERKERRERKKER---------KKKEE 217

Query: 78  REAEAQAAMEAN 89
           R+ E Q   + N
Sbjct: 218 RKKERQKDRQTN 229



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKY--------AKMEAEREAV 62
           G T   GK     EE+  +  +KE ER++  R+ E ERK +          K E  +E  
Sbjct: 124 GRTSKEGKERERKEERKREE-RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182

Query: 63  RQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99
           R+  + +   +K+ ++E E +   E   E      +K
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERK 219



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 14/55 (25%), Positives = 30/55 (54%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79
           E++    KKE ER+E   + +E +K +  K E +++        + G ++++ER+
Sbjct: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 23  DEEKDPDAAKKEE--ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           ++E+  +  KKE+  ER++  R+ ++ R+ K  K   E+E  ++  + + G   KE +E 
Sbjct: 74  EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133

Query: 81  EAQAAMEANSEGSLTRPKK 99
           E +   +        R K+
Sbjct: 134 ERKEERKREERKERERKKE 152


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 6/90 (6%)

Query: 13  TKDMGKMLGGDEEKDPDAAKKEEERQEA---LRQAEEERKAKYAKMEAEREAVRQGIRDK 69
           ++++ K     ++ + +  KKE+ERQE     R+ E ER+ +  + E ERE  R+  R+K
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337

Query: 70  YGIKKKEEREAEAQAAMEANSEGSLTRPKK 99
              +K+ ERE E     +   E    R ++
Sbjct: 338 ---EKERERERERDRDRDRTKERDRDRDRE 364



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 2/89 (2%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEER-KAKYAKMEAEREAVRQGIRDKYGI 72
           +D  +    D  KD   ++++   +E  R+ E ER + +  + E ERE  R+  R++   
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426

Query: 73  K-KKEEREAEAQAAMEANSEGSLTRPKKA 100
           K KK +RE + + A E        R K+A
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEA 455



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 13  TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72
           + D  K      EK  D  ++ E  +E  R+ E ER+ +  + E ERE  R+  +DK   
Sbjct: 374 SSDRNKDRSRSREKSRDRERERERERERERERERERERERER-EREREREREREKDKKRD 432

Query: 73  KKKEEREAEAQAAME 87
           ++++E +A  +  +E
Sbjct: 433 REEDEEDAYERRKLE 447



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 18/98 (18%), Positives = 46/98 (46%), Gaps = 6/98 (6%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE------AVRQGIRDKYGIKKKE 76
           + E++ +  ++ E  ++  R  EE+ +  Y + + ER+      A ++ +++    ++K+
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471

Query: 77  EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
            RE E +A  E      + +  K +     D  ++ D+
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 8   ALGGATKDMGKMLGGDE-EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE-----A 61
           AL    +D  K +  DE ++  +  + EE RQ  L +   +  A+  +ME E E      
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576

Query: 62  VRQGIRDKYGIKKKEEREAEAQAAMEANSE 91
           ++Q    +   ++K+E+E + +  ME   E
Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEE 606



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 16/77 (20%), Positives = 37/77 (48%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           + E++ +  ++ E  +E  R+ E ER+ +  + + ++    +   D Y  +K E +  E 
Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453

Query: 83  QAAMEANSEGSLTRPKK 99
           +AA +   +    R +K
Sbjct: 454 EAAYQERLKNWEIRERK 470



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           D+++D     +    Q+ LR  E+E +A     + E+E + + IR +   +   + +AE 
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE-IRQRLLAEGHPDPDAEL 562

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           Q  ME  +E    +P+    P   +E EE+ E
Sbjct: 563 Q-RMEQEAE-RRRQPQIKQEPESEEEEEEKQE 592



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 3/116 (2%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           +++ + L  +   DPDA  +  E QEA R+ + + K +    E E E  +Q   +K    
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRME-QEAERRRQPQIKQEPESEEEEEE--KQEKEEKREEP 600

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQ 129
            +EE E E +  ++       + P  +   G        DES    +I +   P Q
Sbjct: 601 MEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQ 656


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91
           ++EE RQ+ LR+ ++ER+ +  K E E E + Q       +K++ E E   Q   E   E
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQ------RLKREHEEERREQELAEEEQE 691

Query: 92  GSLTRPKKAIP 102
            +  R K  IP
Sbjct: 692 QARERIKSRIP 702



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER------ 78
           E++ +  ++E  +Q+  R  EEER+ ++ K+E E    +Q  R++   +++EER      
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520

Query: 79  --EAEAQAAMEANSEGSLTRPKK 99
             E E +      SE  L R ++
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQE 543



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 3/75 (4%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84
           E+     ++EE R++ LR+ +EER+ +  + E E E   Q +R +   +++E RE + + 
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE---QEEERREQQLRR 379

Query: 85  AMEANSEGSLTRPKK 99
             +   E  L R ++
Sbjct: 380 EQQLRREQQLRREQQ 394



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 23  DEEKDPDAAKKEEER--QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           +E ++    +++EER  Q+  R+ EEER+ +  + E E E   Q +R +  ++++++   
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391

Query: 81  EAQAAME 87
           E Q   E
Sbjct: 392 EQQLRRE 398



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 1/69 (1%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           +E +D    ++EE RQ+ L++ +EER  +  K E E E + Q  R +  +K++E  E   
Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRLKRE-EVERLEQEERREQRLKREEPEEERR 630

Query: 83  QAAMEANSE 91
           Q  +++  +
Sbjct: 631 QQLLKSEEQ 639



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 7/80 (8%)

Query: 24  EEKDPDAAKKEEE-------RQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76
           EE+     K+EEE       R++ L++ +EER+ +  K E ER   R     +  ++++ 
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 77  EREAEAQAAMEANSEGSLTR 96
           +RE   +   E   E  L R
Sbjct: 603 KREEVERLEQEERREQRLKR 622



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           + L  ++E++    K E+ER+E   + E+E +  + K E E E   Q  R K  +K+ +E
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-RRKQQLKRDQE 481

Query: 78  RE 79
            E
Sbjct: 482 EE 483



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 17/65 (26%), Positives = 35/65 (53%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91
           +++EER+E L + EEE++ +  + E   +  ++  RD+   +++E R+   +   E   E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599

Query: 92  GSLTR 96
             L R
Sbjct: 600 QRLKR 604



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 18/68 (26%), Positives = 35/68 (51%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           E ++    +++EER++ L + EEER+ +  K E E    ++  R++    ++EER  +  
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620

Query: 84  AAMEANSE 91
              E   E
Sbjct: 621 KREEPEEE 628



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 17/94 (18%), Positives = 46/94 (48%), Gaps = 8/94 (8%)

Query: 14   KDMGKMLGGDEEKDPDAAKKE--------EERQEALRQAEEERKAKYAKMEAEREAVRQG 65
            +D+  +LG  +E+D +  ++          E ++  R+ ++E K +  K + E++ +R+ 
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324

Query: 66   IRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99
              +K   ++ + +  E +  ++   E  L R ++
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 7/100 (7%)

Query: 18   KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
            ++LG + EK     ++++ R+E   Q EEE+      +  ERE  R+   ++   KK E 
Sbjct: 972  QLLGEEPEKRRRQEREKKYREEEELQQEEEQ-----LLREEREKRRRQEWERQYRKKDEL 1026

Query: 78   REAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117
            ++ E Q   E   +  L   ++       +E+++E+E +L
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYRE--EEELQQEEEQLL 1064



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 32  KKEEER---QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEA 88
           K+EEER   QE  R+ +E R+ +  + E +    ++  R++   +++EE   E Q   E 
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368

Query: 89  NSE 91
             E
Sbjct: 369 EEE 371



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 15/61 (24%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVR-QGIRDKYGIKKKEEREAEA 82
           E ++    +++EER+E   + +EE +    ++ +E++  R Q  R +  +K++EE+  E 
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560

Query: 83  Q 83
           +
Sbjct: 561 E 561



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 12/48 (25%), Positives = 28/48 (58%)

Query: 32   KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79
            +K  E ++ LR+ E ERK    + +  R+ + +  R++  ++++ E+E
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 24  EEKDPDAAKKEEERQEALR--QAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           E ++ +  ++   R++ LR  Q EE R+ +  + E +    +Q  R +  +++++E   E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348

Query: 82  AQAAMEANSE 91
            Q   E   E
Sbjct: 349 QQLRREQEEE 358



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 23  DEEKDPDAAKKEEE-------RQEALRQAEEERKAKYAKMEAEREAVRQGIR--DKYGIK 73
           ++E+     K+E+E       R+E   + E+ER+ +  K + E E   + ++  ++   +
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKK 99
           ++E RE + +   E   E  L R ++
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEE 524



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 24  EEKDPDAAKKEEER---------QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKK 74
           EE+     K++EE          ++ LR+ +EER+ +  K E E+  + Q  R++   ++
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR-LEQERREQRLKRE 570

Query: 75  KEEREAEAQAAMEANSEGSLTRPKK 99
           +EER  +     E   +  L R ++
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQE 595



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 14/92 (15%), Positives = 41/92 (44%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           +EE+     ++  ER++ L+  EEE + +  +   + +    G+++    ++ +E+  + 
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           +   +   E    R      P   +++ +E +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 17/121 (14%)

Query: 6    KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65
            K AL    +   ++L  +EE+      + EER++  RQ +E +  +  +++ E E + + 
Sbjct: 892  KPALQEQLRKEQQLLQEEEEE-----LQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946

Query: 66   IRDK---------YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
             R+K         Y   KK +++ E     E        R KK       +E+++E+E +
Sbjct: 947  EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE---EELQQEEEQL 1003

Query: 117  L 117
            L
Sbjct: 1004 L 1004



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 8/76 (10%)

Query: 24   EEKDPDAAKKEEERQEALRQAEEERKAK--------YAKMEAEREAVRQGIRDKYGIKKK 75
            +E++    ++EE +QE  +   EER+ +        Y K E  ++   Q +R++   +++
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103

Query: 76   EEREAEAQAAMEANSE 91
            +ERE + +   E   E
Sbjct: 1104 QERERQCREEEELQQE 1119



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           EE++ +  K+E   ++   + +EE   +  +++ E E +R+  R +     + ER+ E Q
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL----RRERQEEEQ 295

Query: 84  AAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
                  E  L R ++       +E  E+ E
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQE 326



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 12/56 (21%), Positives = 30/56 (53%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAME 87
           ++EE R++ LR+ +EE + +      ++    Q +R +  ++++++   E Q   E
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 19/86 (22%), Positives = 41/86 (47%), Gaps = 9/86 (10%)

Query: 23  DEEKDPDAAKKEEERQE--ALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           +E +     ++++ER+E    R+ EEER  +  K E E E   Q + ++   + +E  ++
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699

Query: 81  -------EAQAAMEANSEGSLTRPKK 99
                  + ++  +A      +RP+K
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRK 725



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 20/100 (20%), Positives = 49/100 (49%), Gaps = 7/100 (7%)

Query: 18   KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
            ++L  + EK     ++ + R+E   Q EEE+  +  + +  R+ + +  R++  ++++EE
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151

Query: 78   REAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117
            +    +       E  L R  +       +E+++E+E +L
Sbjct: 1152 QLLREEPEKRRRQE--LERQYRE-----EEELQQEEEQLL 1184



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 2/53 (3%)

Query: 33  KEEERQEALRQAEEERKAKYAKMEAER--EAVRQGIRDKYGIKKKEEREAEAQ 83
           +EEER    +Q EE+R+    + +AE   E  RQ +  +  ++++ ER+  A+
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 19/95 (20%), Positives = 51/95 (53%), Gaps = 9/95 (9%)

Query: 25  EKDPDAAKKEEER--QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           ++D +  + +E+R  Q+   Q EEERK +   + A + A+++ +R +  + ++EE E + 
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA-KPALQEQLRKEQQLLQEEEEELQR 915

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117
           +   +   +    + ++       +++++E+E +L
Sbjct: 916 EEREKRRRQEQERQYREE------EQLQQEEEQLL 944



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 21/87 (24%), Positives = 45/87 (51%), Gaps = 4/87 (4%)

Query: 32   KKEEERQEALRQAEEERKAKYAKMEAEREA-VRQGIRDKYGIKKKEEREAEAQAAMEANS 90
            ++ +ER+   R+ EE ++ +   +  ERE   RQ +  +Y  +K+EE + E +  +    
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY--RKEEELQQEEEQLLREEP 1098

Query: 91   EGSLTRPKKAIPPGCGDEVEEEDESIL 117
            E    R ++       +E+++E+E +L
Sbjct: 1099 E-KRRRQERERQCREEEELQQEEEQLL 1124



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 12/56 (21%), Positives = 29/56 (51%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79
           E+++     +E +++E     EEE K +  +   ERE   Q + ++  ++++E  +
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 38.9 bits (89), Expect = 0.001
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           D E+D D     E  +E  R  E+ER+ +  + E ERE  R+         ++ ERE E 
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERE---------RERERERER 774

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           + A E + E    R  +    G  D  E+ +E
Sbjct: 775 ERARERDKERERQRDWEDKDKGRDDRREKREE 806



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 7/83 (8%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKM-------EAEREAVRQGIRDKYGIKKK 75
           + E+D +  K+ E  +E  R+ E ER+ +  +        + ERE  R+  R+K   +++
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753

Query: 76  EEREAEAQAAMEANSEGSLTRPK 98
           EERE E +   E   E    R +
Sbjct: 754 EERERERERERERERERERERER 776



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE---ERE 79
           D+ +D  A +++ ER+    +  E  + +  + E ERE  R+  R++   ++KE   ER+
Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERD 728

Query: 80  AEAQAAMEANSEGSLTRPKK 99
            +     E   E    R K+
Sbjct: 729 RDRDHDRERERERERDREKE 748



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAK-MEAEREAVRQGIRDKYGIKKKEEREAE 81
           + E + + A++ E  +E  R  E +R   + +  E ERE  R+  R++   +++ ERE E
Sbjct: 704 ERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE 763

Query: 82  AQAAMEANSEGSLTRPK 98
            +   E   E    R +
Sbjct: 764 RERERERERERERARER 780



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 15/86 (17%)

Query: 21  GGDEEKDPDAAKKE-------EERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           G ++E + D  ++E       + R E  R+ + ER+      + ERE  R+  RD+   +
Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERER-----DRERERERERERDR---E 700

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKK 99
           +++ERE E + A E   E    R ++
Sbjct: 701 REKERELERERAREREREREKERDRE 726



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAER------EAVRQGIRDKYGIKKKEEREAEAQAA 85
           +K E ++ + R  E+E K K + ++ +R      E+ R   +D  G  + E+RE   +A 
Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953

Query: 86  MEANSEGSLTRPKKAIPPGCGDEVEEEDESILDT 119
            E   +  +   KK I     D+V  E  +I  T
Sbjct: 954 DENKKKAKI--QKKPIKKKKEDDVGIERGNIETT 985


>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
           sapiens]
          Length = 475

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 16/88 (18%)

Query: 11  GATKDMGKM---LGGDEEKDPDAAKK-EEERQEALRQAEEERKAKYAKMEAEREAVRQGI 66
           G +K  GKM   +  D E +  A +K EEE +E L +  +E+K + AK+  E+       
Sbjct: 37  GKSKGGGKMNEEISSDSESESLAPRKPEEEEEEELEETAQEKKLRLAKLYLEQ------- 89

Query: 67  RDKYGIKKKEEREAEAQAAMEANSEGSL 94
                ++++EE +AEA+A  E    G L
Sbjct: 90  -----LRQQEEEKAEARAFEEDQVAGRL 112


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 5/81 (6%)

Query: 23  DEEKDPDAAKKEEERQ---EALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE-ER 78
           D ++D D  +KE ERQ   +  R+ E +R+ +  K E +RE  R+  R++   +++E ER
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETE-RKRERQRERERERERNRKRERERERER 325

Query: 79  EAEAQAAMEANSEGSLTRPKK 99
           E E Q   E + E    R +K
Sbjct: 326 ERERQRETERDREKERERKRK 346



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 13/89 (14%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKA------------KYAKMEAEREAVRQGIRDKY 70
           + +K+ +  K  +ER+E  RQ E+E K             +  + E E E  RQ  R++ 
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER- 232

Query: 71  GIKKKEEREAEAQAAMEANSEGSLTRPKK 99
             ++K ERE E QA  E  SE    R K+
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKE 261



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 16/64 (25%), Positives = 37/64 (57%), Gaps = 5/64 (7%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERK-----AKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           + +++ +  +++E  ++  RQ E +R+      +  + +AERE  R+  RD+   +++EE
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387

Query: 78  REAE 81
           RE +
Sbjct: 388 RERD 391



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAK-MEAEREAVRQGIRDKYGI---KKKEEREA 80
           E+D +  +K E ++E  R+ E  RK +  +  E ERE  R+  RD+      K+K + E 
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351

Query: 81  EAQAAMEANSEG 92
           + +   +   EG
Sbjct: 352 DRERNRQTGREG 363



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           D E+D     + E  ++A R+   ER+ +  K E ERE  R   RD+   +++ + + + 
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDK-ERERERDRDRDRDRRQKERERQTDRKR 287

Query: 83  QAAMEANSEGSLTRPKK 99
           Q   E + E    R ++
Sbjct: 288 QRRTERDRETERKRERQ 304



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE-----E 77
           D E++    ++   + E  R+ E ER  + A+   ERE  R   R K   ++ E     +
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411

Query: 78  REAEAQAAMEANSEGSLTRPK 98
           RE E Q   E + E    R +
Sbjct: 412 RETEKQREREKDRESERGRER 432



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 6   KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65
           ++ LG A KD     G D E++    K+ E R+E  RQ E E      K E  RE  R  
Sbjct: 39  RRGLGQAHKDAD---GDDRERNRQ--KERERRREK-RQTERETD---RKRERRREKDRHR 89

Query: 66  IRDKYGIKKKE-EREAEAQAAMEANSEGSLTRPKK 99
            RD++  ++++ E+E E Q   E + +    R ++
Sbjct: 90  KRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           KD  +      E+  D  +KE ERQ    +  +  K +  + E ERE  R+G R +   +
Sbjct: 85  KDRHRKRDRHRERQRDR-EKERERQTDRERDRQREKERNRQKERERETEREGERGR-DRQ 142

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKK 99
              +RE E Q   E   E    R ++
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQ 168



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 15/88 (17%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE------ 76
           + E+  DA K+ E + +  RQ + ER  +    E ERE  RQ  R++   ++KE      
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQ---KEREREKNRQERRERERQREKENKTEDR 204

Query: 77  ------EREAEAQAAMEANSEGSLTRPK 98
                 ERE E +   E   +    R +
Sbjct: 205 HSERGRERERERETETETERKRQTDRER 232



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 17/86 (19%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           ++  K    +   + +  + +E  +E  R  + +R+ K  + + +R+  R+  RD+   +
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKK 99
           K+ ER+ E +   E N +    R ++
Sbjct: 300 KR-ERQRERERERERNRKRERERERE 324



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 9/67 (13%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84
           + + D  +  +  +E  RQAE ER       E ERE  RQ  R++   +++ +R+ + Q 
Sbjct: 348 QTEMDRERNRQTGREGRRQAERER-------ERERERDRQSARERE--ERERDRDRDRQK 398

Query: 85  AMEANSE 91
             E  +E
Sbjct: 399 ERERQTE 405



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 21  GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           G D + D    ++E ERQ    +  E +  +  + + ER   ++  R+K    ++E RE 
Sbjct: 138 GRDRQTD---GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK---NRQERRER 191

Query: 81  EAQAAMEANSE 91
           E Q   E  +E
Sbjct: 192 ERQREKENKTE 202



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 23  DEEKDPDAAK-KEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKK-EEREA 80
           + E+D D  + KE ERQ    +  +    K  + E +RE+ R   R +   K+K  ER+ 
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446

Query: 81  EAQAAMEANSE 91
           E Q   +A  +
Sbjct: 447 ERQTDRQAGRQ 457


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 2/74 (2%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           K+  K    +  K+ +  +KE E+Q   R+ +E RK K  K + ER+  ++G R++   K
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK--QRGRRERKKKK 118

Query: 74  KKEEREAEAQAAME 87
           +++ERE E +   E
Sbjct: 119 ERKERERENKQRRE 132



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 23/86 (26%), Positives = 40/86 (46%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           K+  K      EK+    KKE++++E  ++   ERK K  + E ERE  ++  R +   +
Sbjct: 80  KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKK 99
           KK+ R+   +       E    + KK
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKK 165



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84
           +++ +  K+  ER++  R+ E+ERK +  K E ++   R+  R K   +K++ERE + + 
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE--RGKERERKRKEREKQRKE 88

Query: 85  AMEANSEGSLTRPKK 99
             E          KK
Sbjct: 89  RREKERRKRKKEKKK 103



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 22  GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           G  E+     +KE ER+   +Q  E ++ K  K +  +E  R+  R K   K+K+ ++ E
Sbjct: 110 GRRERKKKKERKEREREN--KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167

Query: 82  AQAAMEAN 89
            +   E N
Sbjct: 168 REKKRERN 175



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 5/70 (7%)

Query: 22  GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           G  E+     KKEE  ++  R  +E +K +  K   ER+  R+  R     +KK+ER+ +
Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER-----RKKKERKKD 208

Query: 82  AQAAMEANSE 91
            +   + +S+
Sbjct: 209 RKTDRQTDSQ 218



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER--EA 80
           + E      +K ++R++  R+ E +R+ +  K E +R+  ++  R+K   + ++ER  E 
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183

Query: 81  EAQAAMEANSEGSLTRPKK 99
           E +   E   E    R KK
Sbjct: 184 ERKERRERKKERKKERRKK 202



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 6/78 (7%)

Query: 25  EKDPDAAKKEEERQEALRQAE---EERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           E+     +K++ R+E  R+ E    ERK K  K E ERE  R+  R++   KK+ ER+  
Sbjct: 132 ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE-EREKKRE--RNRKERKKERERKER 188

Query: 82  AQAAMEANSEGSLTRPKK 99
            +   E   E    + +K
Sbjct: 189 RERKKERKKERRKKKERK 206



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
          E ++ +  K+E E++   R+ E  +K K  + + ER   R+  R +   ++KE RE E
Sbjct: 39 ERREREKRKREREKE---RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI-KKKEEREAE 81
           ++E+  +  KKE+++++  R+  +ER+ K  + E +R+  R+  R K    KKK ER+  
Sbjct: 51  EKERKRERGKKEKKKRKK-RERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR 109

Query: 82  AQAAMEANSE 91
            +   +   E
Sbjct: 110 GRRERKKKKE 119



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 14/76 (18%), Positives = 35/76 (46%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           +E++ +  ++ E +++  R+ +  ++ K  K   +RE  R+  + +   KK+E    E +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 84  AAMEANSEGSLTRPKK 99
              E        + +K
Sbjct: 181 KERERKERRERKKERK 196


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 11/113 (9%)

Query: 6   KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65
           +Q LG   +D  +   GDE   P +    ++  E     ++  K+K A  + ER  V+  
Sbjct: 146 EQGLGKREEDEPEERSGDET--PGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVK-- 201

Query: 66  IRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118
                  ++++E++   +A  E   E   +R K  +PP    + EEED+++++
Sbjct: 202 -------RQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVN 247



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 14/27 (51%), Positives = 20/27 (74%), Gaps = 3/27 (11%)

Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEE 47
          GGDEE+D +   +EEE +EAL + E+E
Sbjct: 72 GGDEEEDEE---EEEEDEEALLEDEDE 95


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 3/73 (4%)

Query: 27  DPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAM 86
           + +A K+EEER+   RQ EE++K +  +     E  ++   ++  +K+K+E+E + +A +
Sbjct: 448 EEEARKQEEERK---RQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMI 504

Query: 87  EANSEGSLTRPKK 99
           E   E + T+ ++
Sbjct: 505 EKQKEAAETKARE 517



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK--YGIKKKEEREAE 81
           +++  +  + E+E Q+ L + E +RKA+  ++  E EA +Q    K     KKK+E E +
Sbjct: 414 QKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEK 473

Query: 82  AQAAMEA 88
            +A  EA
Sbjct: 474 RKAGEEA 480



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 10/105 (9%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           K  G ++ K  + AK++ E +  L++ +E+ K + A +E ++EA     R+     + E 
Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526

Query: 78  REAEAQAAME-----ANSEGSLTRPKKA-IPPGCGDEVEEEDESI 116
            +   Q   E        +  + R +K+ +PP    +V++ED  +
Sbjct: 527 EQIMLQIEQERLERKKRIDEIMKRTRKSDVPP----QVKKEDPKV 567



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 10/99 (10%)

Query: 8   ALGGATKD---MGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAER----E 60
           A GG  ++   +GK   G  +    A    E+R++A  Q E+E + +  K E +R    E
Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435

Query: 61  AVRQGIRDKYGIK---KKEEREAEAQAAMEANSEGSLTR 96
             R+   ++  ++   +K+E E + Q   +   EG   R
Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKR 474



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 20/126 (15%)

Query: 24  EEKDPDAAKKE----EERQEALRQAEEERKAKYAKMEAEREAV---RQGIRDKYGIKKKE 76
           EE++   A +E    E+++ A  Q E++ + ++ K+E +R+     R  + +K   K +E
Sbjct: 63  EEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLRE 122

Query: 77  ERE-AEAQAAMEANSEGSLTRPKK-------AIPPGCGDEVEEEDESILDTVIKYLPGPL 128
           E E  EA           L   KK       AI PG  D  ++     L T    LP P 
Sbjct: 123 EEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACDK-----LSTSTMSLPKPT 177

Query: 129 QDMLKK 134
           +  + K
Sbjct: 178 EPPMNK 183


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 13/98 (13%)

Query: 23   DEEKDPDAAKKEEE--RQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
            +EE++ +  ++EEE   +E  R+ EEE + K  + E E +  ++  + K  +++KEE   
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307

Query: 81   EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118
            E +  M      SL+           DE EEE+   L+
Sbjct: 2308 EKEEIMSEEETESLS-----------DEEEEEESCSLE 2334



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 3/111 (2%)

Query: 13   TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGI---RDK 69
            +++M  +L   E+++  ++++EEER+E   + EEE + +  + + E E   + +    ++
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286

Query: 70   YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
               KKKE+++ E Q   E   E      ++       +E EEE  S+ + V
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 10/101 (9%)

Query: 22   GDEEKDPDAAKKEE--------ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
            GD+ K+  +++ +E        E  E+L    E++++  ++ E ERE   +  R++  ++
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE--REEEEVR 2263

Query: 74   KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
            ++EE   E +   E   E      KK       +EV+E++E
Sbjct: 2264 EEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 23   DEEKDPDAAKKEEERQEALRQAEEERK-AKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
            +EE   +  +KE++  E  R  +EE K A+  +  A  E  R     K   ++++  + E
Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE 1606

Query: 82   AQAAME 87
             Q A E
Sbjct: 1607 RQLAQE 1612



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 23/114 (20%), Positives = 49/114 (42%), Gaps = 6/114 (5%)

Query: 24   EEKDPDAAKKEE---ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
            E+K  +  +KEE   E++E + + E E  +   + E       +  R+K  +KK+++ + 
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352

Query: 81   EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQDMLKK 134
            + Q          +    + +P G G  +      +L + +K L     +M +K
Sbjct: 2353 QEQRRKSLRGRERVLSILRGVPHGKGRAIR---LGVLKSPLKKLMSTALEMKEK 2403


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER----- 78
           EE++    K++E+R+E  ++ E+++K K  +   E+E   +  + K   KK+EE      
Sbjct: 20  EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79

Query: 79  -EAEAQAAMEANSEGSLTRPKK 99
            E E +   E   EG   + KK
Sbjct: 80  EEEEEEKEEEEKEEGRRRKKKK 101



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 1/67 (1%)

Query: 13  TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72
           TK+  K    +EE+     K++++++E  R+ EEE + +  K E E+E  R+  + K   
Sbjct: 46  TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE-EKEEEEKEEGRRRKKKKKRR 104

Query: 73  KKKEERE 79
           +K+EE E
Sbjct: 105 RKEEEEE 111



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 6/83 (7%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91
           KKE E  E   + EEE + +  + E  +E      + K   KKK+ +E E +   E   +
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKE------KRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 92  GSLTRPKKAIPPGCGDEVEEEDE 114
               + KK       +E EEE+E
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEE 83



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 9/91 (9%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           ++K     ++ EE +E   + E+E K K  + E  +E  ++  + K   K+KE+ E E +
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEKK 61

Query: 84  AAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
              +        R KK       +E EEE+E
Sbjct: 62  RKRK--------RKKKKEEEEREEEEEEEEE 84



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 14/90 (15%)

Query: 24  EEKDPDAAKKEEERQEALRQAE--EERKAKYAKM------------EAEREAVRQGIRDK 69
           EE +     +EEE +E  R+ +  E+RK K  K             E E++  R+  + K
Sbjct: 11  EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70

Query: 70  YGIKKKEEREAEAQAAMEANSEGSLTRPKK 99
              +++EE E E +   E   E    R KK
Sbjct: 71  EEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 11/47 (23%), Positives = 31/47 (65%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69
           +EE++ +  K+EEE++E  R+ +++++ +  + E +++  R+  + K
Sbjct: 77  EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 12/42 (28%), Positives = 28/42 (66%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64
           +EE++ +  +KEEE +E  R+ ++++K +  + E E++  R+
Sbjct: 76  EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 14/52 (26%), Positives = 28/52 (53%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKK 74
           +EE++ +  ++EEE++E  ++    RK K  +   E E  ++  R +   KK
Sbjct: 72  EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKY-AKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           EE++   A++E  R +A  QAEE R+ +  A++E  R    +  R    +K++EE EAE 
Sbjct: 309 EERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEG 368

Query: 83  QAAMEANSEGSLTRPKKAI-PPGCGDEVEEEDE 114
              +E   E  +  P +A+   G G    EE++
Sbjct: 369 WEELE-QQEAEVQGPPEALEETGEGRRGAEEED 400


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 17/103 (16%)

Query: 21  GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           GG+E   P   K+E+E  E     EEE        E E E    G+ D  G++ K+   A
Sbjct: 570 GGEEGDGPPGGKEEDEDDEEEEDEEEE--------EDEEEGEEGGLLD-CGLRLKKVSFA 620

Query: 81  EAQAAMEAN--------SEGSLTRPKKAIPPGCGDEVEEEDES 115
           E  A              EGS T  +K + PG     EE+DE+
Sbjct: 621 ERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEEDDEA 663


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 18/105 (17%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70
           GA  D  +   G  EK+  + K+E E++E   +AE E +   AK E              
Sbjct: 542 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE-------------- 585

Query: 71  GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
             KK EE+  E     E  ++  + +P+KA  P     VEE+ +S
Sbjct: 586 --KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 5   MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64
           M++AL   T+++   +   +E+  +AA+++EE  EA    EEE  AK + ++A    V++
Sbjct: 469 MEEALTAITEELAVSM---KEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKE 522

Query: 65  GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
              +K   + +EE E E + A    +E   +  + +     G++ E E E+
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 24/107 (22%)

Query: 23  DEEKDPDAAKK-------------EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69
           + E++  AAKK             E E++E   Q EEE + + AK +   E    G  +K
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----GGSEK 555

Query: 70  YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
            G  +KEE E E +   EA +EG     K+        +VEE+ E +
Sbjct: 556 EGSSEKEEGEQE-EGETEAEAEGEEAEAKEE------KKVEEKSEEV 595



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           +EEK+   A KEE+ ++   + ++  + K A+   + EAV + +     +K   E+E + 
Sbjct: 704 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK- 762

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
                   EG   + +K      G+   EE+ S
Sbjct: 763 -------EEGKPLQQEKEKEKAGGEGGSEEEGS 788



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 25/113 (22%)

Query: 5   MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQ--------------------EALRQA 44
           +K  L   TK+ GK L  ++EK+    +   E +                    E   + 
Sbjct: 753 VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 812

Query: 45  EEERKAKYAKMEAEREAVRQGI-----RDKYGIKKKEEREAEAQAAMEANSEG 92
           E+E K K +  E E+  V  G+      +K G  K EE+    +   +  SEG
Sbjct: 813 EQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 34  EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90
           E    + + QAEE  K +YAK+    E      ++K  I+  +E  AE +  +++ S
Sbjct: 278 ESHSDQNMHQAEEWFKCRYAKLTEAAE------QNKEAIRSAKEEIAEYRRQLQSKS 328



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 24  EEKDPDAAKK---EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           EEK      K   EE+ +  + ++  E KAK    ++  E  +       G +K+EE + 
Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 708

Query: 81  EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
             +A  E   E    +PK  +P     E   ++E++ + V
Sbjct: 709 VKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 747


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 18/105 (17%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70
           GA  D  +   G  EK+  + K+E E++E   +AE E +   AK E              
Sbjct: 166 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE-------------- 209

Query: 71  GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
             KK EE+  E     E  ++  + +P+KA  P     VEE+ +S
Sbjct: 210 --KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 5   MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64
           M++AL   T+++   +   +E+  +AA+++EE  EA    EEE  AK + ++A    V++
Sbjct: 93  MEEALTAITEELAVSM---KEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKE 146

Query: 65  GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
              +K   + +EE E E + A    +E   +  + +     G++ E E E+
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 24/107 (22%)

Query: 23  DEEKDPDAAKK-------------EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69
           + E++  AAKK             E E++E   Q EEE + + AK +   E    G  +K
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----GGSEK 179

Query: 70  YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
            G  +KEE E E +   EA +EG     K+        +VEE+ E +
Sbjct: 180 EGSSEKEEGEQE-EGETEAEAEGEEAEAKEE------KKVEEKSEEV 219



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           +EEK+   A KEE+ ++   + ++  + K A+   + EAV + +     +K   E+E + 
Sbjct: 328 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK- 386

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
                   EG   + +K      G+   EE+ S
Sbjct: 387 -------EEGKPLQQEKEKEKAGGEGGSEEEGS 412



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 25/113 (22%)

Query: 5   MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQ--------------------EALRQA 44
           +K  L   TK+ GK L  ++EK+    +   E +                    E   + 
Sbjct: 377 VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 436

Query: 45  EEERKAKYAKMEAEREAVRQGI-----RDKYGIKKKEEREAEAQAAMEANSEG 92
           E+E K K +  E E+  V  G+      +K G  K EE+    +   +  SEG
Sbjct: 437 EQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 24  EEKDPDAAKK---EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           EEK      K   EE+ +  + ++  E KAK    ++  E  +       G +K+EE + 
Sbjct: 273 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 332

Query: 81  EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120
             +A  E   E    +PK  +P     E   ++E++ + V
Sbjct: 333 VKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 371


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 10/94 (10%)

Query: 21  GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80
           GG+EE        E E +E  R+ EEE++ +  K E E E V      + G +KKEER  
Sbjct: 730 GGEEEHG------EGEEEEGDREEEEEKEGE-GKEEGEGEEVEGEREKEEGERKKEERAG 782

Query: 81  EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           + +   E   EG     ++    G G+E EE  E
Sbjct: 783 KEEKGEE---EGDQGEGEEEETEGRGEEKEEGGE 813



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 6/93 (6%)

Query: 22  GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           G+ E++    K EEE +E   + EEE        E E E       ++ G  + EE E E
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEG------EGEGEDGEGEGEEEEGEWEGEEEEGE 963

Query: 82  AQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
            +   E   EG     +     G G+  EEE E
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 3/105 (2%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70
           G   + GK  G  EE++ +   +EEE +    + E E +    K E E E        + 
Sbjct: 816 GGEVEEGK--GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873

Query: 71  GIKKKEEREAEAQAAMEANSEGSLTRPK-KAIPPGCGDEVEEEDE 114
           G  + EE E E +   E   EG     + +    G G+  EEE E
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 9/94 (9%)

Query: 22   GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
            G+EE+     ++EE  +E   + E E + +    E E   V   +  + G  + EE E E
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 82   AQA-AMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
             +    E   EG   R  +        E EEE+E
Sbjct: 1041 EEGEEREKEGEGEENRRNR--------EEEEEEE 1066



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70
           G  ++ G+   G+EE +    + EEE  E   + E E + +  + E E E   +G  ++ 
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915

Query: 71  GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
             + K E E E     E   EG     +     G G+  EEE E
Sbjct: 916 EGEGKGEEEGE-----EGEGEGEEEEGEGEGEDGEGEGEEEEGE 954



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 28/113 (24%), Positives = 46/113 (40%), Gaps = 10/113 (8%)

Query: 11  GATKDMGKMLGGDEEKDPDAAKKE---------EERQEALRQAEEERKAKYAKMEAEREA 61
           G  +  G+ + G+ EK+    KKE         EE  +     EEE + +  + E   E 
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814

Query: 62  VRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
               + +  G +++EE E E +   E   E      ++    G G+E  EE E
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEE-EGEGEEEEGEGEEEEGEGKGEEEGEEGE 866



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 5/106 (4%)

Query: 12  ATKDMGKMLGGDEE--KDPDAAKKEEERQEALRQAEEER---KAKYAKMEAEREAVRQGI 66
           A K+  K   G+E+  K+ +   ++E  QE     EEE    + +    E E E   +G 
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756

Query: 67  RDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEE 112
            +  G + + ERE E     +    G   + ++    G G+E E E
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 16/71 (22%), Positives = 36/71 (50%)

Query: 11   GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70
            G  ++ G++ G  E ++ +   +EEE +E   + E+E + +  +   E E   +G   + 
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072

Query: 71   GIKKKEEREAE 81
            G ++ E ++ E
Sbjct: 1073 GEEENERQDGE 1083



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 6/109 (5%)

Query: 10   GGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69
            G   ++ G+  G +EE + +  ++ E  +E   + EEE + +  + E E E       ++
Sbjct: 979  GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE-VEGEVEGEEGEGEGEEE 1037

Query: 70   YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118
             G ++ EERE E +       E    R ++    G   E  EE+    D
Sbjct: 1038 EGEEEGEEREKEGE-----GEENRRNREEEEEEEGKYQETGEEENERQD 1081


>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
          Length = 314

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 6/98 (6%)

Query: 33  KEEERQEALRQAEEERKAKYAKMEAEREAV----RQGIRDKYGIKKKEEREA-EAQAAME 87
           +E++ ++A R+AEE  + +  ++E++REA      + +R +   K++EER+A E QA  E
Sbjct: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQRE 185

Query: 88  ANSEGSLTRPKKAIPPGCGDEV-EEEDESILDTVIKYL 124
                 L         G G+ + EE+ +S L   I Y+
Sbjct: 186 HEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYI 223



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 11/68 (16%)

Query: 32  KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE----EREAEAQAAME 87
           KKEEER     + +EE + K  + +A+RE       ++Y +K KE    E E   +   E
Sbjct: 157 KKEEERLRLEEEQKEEEERKAREEQAQRE------HEEY-LKLKEAFVVEEEGVGETMTE 209

Query: 88  ANSEGSLT 95
             S+  LT
Sbjct: 210 EQSQSFLT 217


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 24  EEKDPDAAK--KEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81
           +++D + AK  K +E++E     +++ K K ++ + E E V+  +    G+    E +AE
Sbjct: 241 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300

Query: 82  AQAAMEANSEGSLTRPKKAIPPGCGDEVEEE 112
              A E ++EG   +  K    G  +E E+E
Sbjct: 301 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKE 331



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 15/89 (16%)

Query: 14  KDMGKMLGGDEEKDPDAAK---------------KEEERQEALRQAEEERKAKYAKMEAE 58
           KD  K  G  EEK+ +  K               K +E +E  ++ EEER  +  ++EA+
Sbjct: 316 KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAK 375

Query: 59  REAVRQGIRDKYGIKKKEEREAEAQAAME 87
           R+   +  ++K   KK++E+E + +   E
Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKE 404



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 5   MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64
           M++AL    ++  +    +EE+     + E +R+E  R  +E+R+ K  K +  +E +++
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403

Query: 65  GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99
               K   K + E  A A+A ++      +  P K
Sbjct: 404 --EGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 24/105 (22%)

Query: 23  DEEKDPDAAKKEEERQ---------EALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           ++E+ P   + EEE           EA+   EE  K +  K+  E   V++   ++   +
Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE---VKENPEEEEEEE 538

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118
           ++EE + E++   E   E              G E +EEDE + D
Sbjct: 539 EEEEEDEESEEEEEEEGESE------------GSEGDEEDEKVSD 571



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84
           E++ +  ++EEE +E+  + EEE +++ ++ + E E V         + KK  +E  + +
Sbjct: 532 EEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDS 591

Query: 85  AMEANSEGSLTRPKKA 100
             E +S+   T+ ++A
Sbjct: 592 --EYDSDDDRTKEERA 605



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 15/69 (21%), Positives = 40/69 (57%), Gaps = 3/69 (4%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAK---YAKMEAEREAVRQGIRDKYGIKKKEERE 79
           +++ + D  KK++++++  ++ +E+ K K    A ++A +EA+ +   ++   K++EE  
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365

Query: 80  AEAQAAMEA 88
            +    +EA
Sbjct: 366 IKRLEELEA 374



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 21  GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEA----EREAVRQGIRDKYGIKKKE 76
           G  ++KD    K E+E +E  ++    +    A  EA    + E  RQ   ++  IK+ E
Sbjct: 311 GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370

Query: 77  EREAE 81
           E EA+
Sbjct: 371 ELEAK 375


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 14/106 (13%)

Query: 21  GGDE---EKDPDAAKKEEERQEA--------LRQAEEERKAKYAKMEAEREAVRQGIRDK 69
           GGDE   EK+ +  ++E+E++E         L Q  +E +    K E  ++   +G+R+ 
Sbjct: 738 GGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVRED 797

Query: 70  YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115
              + K +RE     A +   +G  +R  +A   G   EV +E ES
Sbjct: 798 ---EDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES 840



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 14/121 (11%)

Query: 6   KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEA---------LRQ-AEEERKAKYAKM 55
           KQA  G   D+ +   G  E   +A K  E+R EA         LR+ + EE +AK  K 
Sbjct: 661 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS 720

Query: 56  EAEREA---VRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGC-GDEVEE 111
           + +++A     +G+ +  G +  +E+E E +   +   E +     + +  G   D+V E
Sbjct: 721 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE 780

Query: 112 E 112
           E
Sbjct: 781 E 781


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           ++  +M+   EEK  +  +K  E++E +R+ EE+ + +  KM+ + E +R+      G +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687

Query: 74  KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCG-DEVEEEDESILD 118
           +K   + E     E    G   +         G +E+ E++E I D
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 10/92 (10%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           D+E+     ++  ER++ +R+ EE  + +  KM+ + E +R+          +EE+  E 
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQ 600

Query: 83  QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114
           +  M+   E    + +K       D+++E++E
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 18/77 (23%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYG-- 71
           ++  + + G EEK  +  +K + ++E +R+ EE+ + +  KM  + E +       +G  
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 722

Query: 72  -IKKKEEREAEAQAAME 87
            +++KEER  + +  M+
Sbjct: 723 EMREKEERIRDQKEKMQ 739



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82
           ++EK+    +KE   Q+ LR+ EE+ + +  KM  + E +R+    +  + ++EER  E 
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQ 343

Query: 83  QAAMEANSE 91
           +  M    +
Sbjct: 344 EKQMREQEQ 352



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77
           K +   E+K  D  ++  E+ E LR+ +EER  +  KM  + E +++  R    I+++E+
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEEER----IREREK 399

Query: 78  REAEAQAAMEANSE 91
           +  E +  M    E
Sbjct: 400 KMREEEETMREQEE 413



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 17/78 (21%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           ++  K +  +EE   +  +K +E++E +R+ EE+   +  KM+ + E + +   +K   +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ-EEKMWEQ 621

Query: 74  KKEEREAEAQAAMEANSE 91
           ++E++  E +  M    E
Sbjct: 622 EEEDKMQEQEEMMWEQEE 639



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 22/104 (21%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 18  KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY-----GI 72
           KM   +E+      K  E+ ++   Q EE++  +  +M  E+E   Q   +K       +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655

Query: 73  KKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
           +++EE+  E +  M+   E    + +K    G  +++ E++E +
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKM--QGQEEKMREQEEKM 697



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 16/71 (22%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREA----VRQGIRDKYGIKKKEEREA 80
           E+D    +KEE  +E  +  ++E K +  K   E+E       + +R++  ++++E++  
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570

Query: 81  EAQAAMEANSE 91
           E +  M    E
Sbjct: 571 EEEEMMREQEE 581



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 24  EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83
           E+K  D  ++  E+ E LR+ +EER  +  KM  + E +R+  + +   KK  ++E + +
Sbjct: 499 EQKMWDQEERMWEQDERLRE-KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557

Query: 84  AAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
                       R ++ +     ++++E++E +
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKM 590



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/74 (20%), Positives = 37/74 (50%)

Query: 14  KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73
           ++  K +   EEK     ++  E++  +R+ EE+ + +  ++  + + +R+  ++    K
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303

Query: 74  KKEEREAEAQAAME 87
           K  E+E + Q   E
Sbjct: 304 KLREQEEQMQEQEE 317


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 22/100 (22%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 17  GKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76
           G  LG  E K  D  +K+E+ ++A   +  + K K ++ + ++E  ++    +   KK  
Sbjct: 292 GAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSS 349

Query: 77  EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116
           ++     +  ++  EGS++  +     G  +E +EE E++
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEAL 389



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 25  EKDPDAAKKEEERQEALRQAEEERKAKYAKMEA--EREAVRQGIRDKYGIKKKEEREAEA 82
           E D D  +K+E+ ++  +++ ++R  K++  ++  E          + G  ++E+ EAEA
Sbjct: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEA 388

Query: 83  QAAMEANSEGSLTRPKKAIPPGC 105
               E   E    +PK A    C
Sbjct: 389 LKEKEKPKEEEWEKPKDAAGLEC 411



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 10  GGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAK 54
           G  + D G +   + E +   A++E+E  EAL++ E+ ++ ++ K
Sbjct: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402


>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 2/101 (1%)

Query: 17  GKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76
           G  LG  E K  D  +K+E+ ++A   +  + K K ++ + ++E  ++    +   KK  
Sbjct: 292 GAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSS 349

Query: 77  EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117
           ++     +  ++  EGS++  +     G  +E +EE E  L
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 11/39 (28%), Positives = 23/39 (58%)

Query: 23  DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREA 61
           + E + ++ + EEE++EA    +E+ K K  + E  ++A
Sbjct: 369 ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.127    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,537,101
Number of Sequences: 37866
Number of extensions: 261422
Number of successful extensions: 5816
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 442
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 2209
Number of HSP's gapped (non-prelim): 2833
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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