BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5729781 complexin 1 [Homo sapiens] (134 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5729781 complexin 1 [Homo sapiens] 265 6e-72 gi|56550065 complexin 2 [Homo sapiens] 228 1e-60 gi|5729783 complexin 2 [Homo sapiens] 228 1e-60 gi|71725345 complexin 3 [Homo sapiens] 59 9e-10 gi|31795561 complexin 4 [Homo sapiens] 49 2e-06 gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 47 6e-06 gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 42 2e-04 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 42 2e-04 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 41 3e-04 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 40 7e-04 gi|148746195 trichohyalin [Homo sapiens] 40 7e-04 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 39 0.001 gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s... 39 0.002 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 39 0.002 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 38 0.002 gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 38 0.002 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 38 0.002 gi|221219020 NYD-SP11 protein [Homo sapiens] 38 0.003 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.003 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 38 0.003 gi|55741655 anoctamin 8 [Homo sapiens] 37 0.004 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 37 0.004 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 37 0.004 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 37 0.004 gi|13027602 DDRGK domain containing 1 [Homo sapiens] 37 0.004 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 37 0.004 gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 37 0.004 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.005 gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 37 0.005 gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 37 0.005 >gi|5729781 complexin 1 [Homo sapiens] Length = 134 Score = 265 bits (678), Expect = 6e-72 Identities = 134/134 (100%), Positives = 134/134 (100%) Query: 1 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE Sbjct: 1 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60 Query: 61 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV Sbjct: 61 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 Query: 121 IKYLPGPLQDMLKK 134 IKYLPGPLQDMLKK Sbjct: 121 IKYLPGPLQDMLKK 134 >gi|56550065 complexin 2 [Homo sapiens] Length = 134 Score = 228 bits (581), Expect = 1e-60 Identities = 113/134 (84%), Positives = 123/134 (91%) Query: 1 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60 M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE Sbjct: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 Query: 61 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 VRQ IRDKYG+KKKEE+EAE +AA+E EGSLTRPKKAIP GCGDE EEE+ESILDTV Sbjct: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 Query: 121 IKYLPGPLQDMLKK 134 +KYLPGPLQDM KK Sbjct: 121 LKYLPGPLQDMFKK 134 >gi|5729783 complexin 2 [Homo sapiens] Length = 134 Score = 228 bits (581), Expect = 1e-60 Identities = 113/134 (84%), Positives = 123/134 (91%) Query: 1 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60 M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE Sbjct: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 Query: 61 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 VRQ IRDKYG+KKKEE+EAE +AA+E EGSLTRPKKAIP GCGDE EEE+ESILDTV Sbjct: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 Query: 121 IKYLPGPLQDMLKK 134 +KYLPGPLQDM KK Sbjct: 121 LKYLPGPLQDMFKK 134 >gi|71725345 complexin 3 [Homo sapiens] Length = 158 Score = 59.3 bits (142), Expect = 9e-10 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 15/136 (11%) Query: 1 MEFVMKQALGGATKDMGKMLGGDEEK---DPDAAKKE-------EERQEALRQAEEERKA 50 M F++K +GG K++ LGG E+K D AA+ + EE Q+ L + + ER A Sbjct: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60 Query: 51 KYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVE 110 ++ + +AER +R RDKY + K E E++ Q A G + P++ D E Sbjct: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115 Query: 111 EEDESILDTVIKYLPG 126 EE+++ + + LPG Sbjct: 116 EEEKASVLGQLASLPG 131 >gi|31795561 complexin 4 [Homo sapiens] Length = 160 Score = 48.5 bits (114), Expect = 2e-06 Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 16/145 (11%) Query: 1 MEFVMKQALGGATKDMGKMLGGDEEK------DPDAAK-----KEEERQEALRQAEEERK 49 M F+MK + K++G G +E K DP AA+ + EE Q+ + + + ER Sbjct: 1 MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERD 60 Query: 50 AKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEV 109 A + + +AER +R +R+KY + K E E + Q A + + P+ D+ Sbjct: 61 AAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGD-----DVDLPEDLRKMVDEDQE 115 Query: 110 EEEDESILDTVIKYLPGPLQDMLKK 134 EEED+ + I+ L D +K+ Sbjct: 116 EEEDKDSILGQIQNLQNMDLDTIKE 140 >gi|148746183 ubiquitin specific protease 35 [Homo sapiens] Length = 1018 Score = 46.6 bits (109), Expect = 6e-06 Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 8/110 (7%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 K GG ++ ++EE ++E + E + + + E ERE + ++ ++K+ E Sbjct: 665 KEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETE 724 Query: 78 REAEAQAAMEANSEGSLTRPKKAIPPG---CGDEVEEEDESILDTVIKYL 124 +EAE + E +S G+ T P AIP G CG E S+LD V +L Sbjct: 725 KEAEQE--KEEDSLGAGTHPDAAIPSGERTCG---SEGSRSVLDLVNYFL 769 >gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] Length = 569 Score = 41.6 bits (96), Expect = 2e-04 Identities = 28/95 (29%), Positives = 48/95 (50%), Gaps = 6/95 (6%) Query: 23 DEEKDPDAAKKEEERQEALRQ---AEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79 +EE + + E+E QEA R ++++RK A + +E + ++ + +KKKEE+E Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394 Query: 80 AEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 E + M+ E R K G+ +EEDE Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEE---GESKDEEDE 426 Score = 30.4 bits (67), Expect = 0.44 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%) Query: 13 TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72 +KD K + +++ + ++E +++E +++ EE K E E E ++Q ++ I Sbjct: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE-------KEEEEEEEMKQK-EEEEEI 410 Query: 73 KKKEEREAEAQAAMEANSE-GSLTRPKKAIPPGCGDEVEEEDESILD 118 + K E E E++ + + + G + PG + E +E LD Sbjct: 411 RNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLD 457 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 41.6 bits (96), Expect = 2e-04 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 28/118 (23%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE--- 79 +E++ + A+ E+E QE L++ +EE +A+ ++ EAER+ + R+K+ ++++ER+ Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEAR-SREEAERQRLE---REKHFQQQEQERQERR 709 Query: 80 ------------------AEAQAAMEANSEGSLTRPKKAI---PPGCGDEVEEEDESI 116 + Q + EAN+ GS P KA+ PG E +++E I Sbjct: 710 KRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPI 767 Score = 36.2 bits (82), Expect = 0.008 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 31 AKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90 A+++ ER+E R+ + ER + + + REA + R+ +++EE+EA +A E Sbjct: 610 AREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA-RRREEQEAREKAQAEQEE 668 Query: 91 EGSLTRPKKAIPPGCGDEVEEE 112 + L + K+ +E E + Sbjct: 669 QERLQKQKEEAEARSREEAERQ 690 Score = 33.9 bits (76), Expect = 0.040 Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%) Query: 36 ERQEALRQ-AEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90 +R+EA R AE+ R+A+ + E+E Q RDK +++ REAEA+A EA + Sbjct: 595 DREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA 650 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 41.2 bits (95), Expect = 3e-04 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 12/78 (15%) Query: 22 GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 G +E++ + K+ ER++ R+ E+ERK + +G ++K G +KKEERE + Sbjct: 51 GKKERESERKKERREREKRKREREKERKRE------------RGKKEKKGERKKEERERK 98 Query: 82 AQAAMEANSEGSLTRPKK 99 + + N EG +K Sbjct: 99 KRRREKENKEGEEKEKRK 116 Score = 37.4 bits (85), Expect = 0.004 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 6/99 (6%) Query: 22 GDEEKDPDAAKKEEERQEALRQAE------EERKAKYAKMEAEREAVRQGIRDKYGIKKK 75 G +EK + K+E ER++ R+ E +E++ K K E R + R++ +K+ Sbjct: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141 Query: 76 EEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 EER+ + E E KK G++ EE E Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180 Score = 36.2 bits (82), Expect = 0.008 Identities = 17/69 (24%), Positives = 38/69 (55%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 E ++ + K+E E++ + ++E+K + K E ER+ R+ +K G +K++ ++ E + Sbjct: 62 ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121 Query: 84 AAMEANSEG 92 + EG Sbjct: 122 ERGRTSKEG 130 Score = 35.0 bits (79), Expect = 0.018 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 6/68 (8%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 K+ G+ +E++ +K EER+E R+ EE K + K +RE R + G K Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE------RKQVGEK 174 Query: 74 KKEEREAE 81 ++E +E E Sbjct: 175 EEERKEKE 182 Score = 35.0 bits (79), Expect = 0.018 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 24 EEKDPDAAKKEEERQEALR--QAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 EE++ + +KE +++E + + EEERK K K +RE R+ + + K++ ER+ E Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211 Query: 82 AQAAMEANSE 91 + E E Sbjct: 212 RKKKEERKKE 221 Score = 34.7 bits (78), Expect = 0.024 Identities = 19/68 (27%), Positives = 33/68 (48%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91 K+ E ++E R+ +ER+ K + E ERE + R++ + +KEE E + E Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190 Query: 92 GSLTRPKK 99 + KK Sbjct: 191 RNRKERKK 198 Score = 34.7 bits (78), Expect = 0.024 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 11/72 (15%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 K +G EE+ + +KE +++E R +E +K + K ER+ R KKKEE Sbjct: 169 KQVGEKEEERKEKERKERKKRE--RNRKERKKERERKERRERKKER---------KKKEE 217 Query: 78 REAEAQAAMEAN 89 R+ E Q + N Sbjct: 218 RKKERQKDRQTN 229 Score = 30.4 bits (67), Expect = 0.44 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 9/97 (9%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKY--------AKMEAEREAV 62 G T GK EE+ + +KE ER++ R+ E ERK + K E +E Sbjct: 124 GRTSKEGKERERKEERKREE-RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182 Query: 63 RQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99 R+ + + +K+ ++E E + E E +K Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERK 219 Score = 29.3 bits (64), Expect = 0.99 Identities = 14/55 (25%), Positives = 30/55 (54%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79 E++ KKE ER+E + +E +K + K E +++ + G ++++ER+ Sbjct: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244 Score = 28.9 bits (63), Expect = 1.3 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 23 DEEKDPDAAKKEE--ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 ++E+ + KKE+ ER++ R+ ++ R+ K K E+E ++ + + G KE +E Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133 Query: 81 EAQAAMEANSEGSLTRPKK 99 E + + R K+ Sbjct: 134 ERKEERKREERKERERKKE 152 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 39.7 bits (91), Expect = 7e-04 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 13 TKDMGKMLGGDEEKDPDAAKKEEERQEA---LRQAEEERKAKYAKMEAEREAVRQGIRDK 69 ++++ K ++ + + KKE+ERQE R+ E ER+ + + E ERE R+ R+K Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKK 99 +K+ ERE E + E R ++ Sbjct: 338 ---EKERERERERDRDRDRTKERDRDRDRE 364 Score = 35.0 bits (79), Expect = 0.018 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEER-KAKYAKMEAEREAVRQGIRDKYGI 72 +D + D KD ++++ +E R+ E ER + + + E ERE R+ R++ Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426 Query: 73 K-KKEEREAEAQAAMEANSEGSLTRPKKA 100 K KK +RE + + A E R K+A Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEA 455 Score = 35.0 bits (79), Expect = 0.018 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 13 TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72 + D K EK D ++ E +E R+ E ER+ + + E ERE R+ +DK Sbjct: 374 SSDRNKDRSRSREKSRDRERERERERERERERERERERERER-EREREREREREKDKKRD 432 Query: 73 KKKEEREAEAQAAME 87 ++++E +A + +E Sbjct: 433 REEDEEDAYERRKLE 447 Score = 30.4 bits (67), Expect = 0.44 Identities = 18/98 (18%), Positives = 46/98 (46%), Gaps = 6/98 (6%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE------AVRQGIRDKYGIKKKE 76 + E++ + ++ E ++ R EE+ + Y + + ER+ A ++ +++ ++K+ Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471 Query: 77 EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 RE E +A E + + K + D ++ D+ Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Query: 8 ALGGATKDMGKMLGGDE-EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE-----A 61 AL +D K + DE ++ + + EE RQ L + + A+ +ME E E Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576 Query: 62 VRQGIRDKYGIKKKEEREAEAQAAMEANSE 91 ++Q + ++K+E+E + + ME E Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEE 606 Score = 29.6 bits (65), Expect = 0.76 Identities = 16/77 (20%), Positives = 37/77 (48%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 + E++ + ++ E +E R+ E ER+ + + + ++ + D Y +K E + E Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453 Query: 83 QAAMEANSEGSLTRPKK 99 +AA + + R +K Sbjct: 454 EAAYQERLKNWEIRERK 470 Score = 27.3 bits (59), Expect = 3.8 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 D+++D + Q+ LR E+E +A + E+E + + IR + + + +AE Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE-IRQRLLAEGHPDPDAEL 562 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 Q ME +E +P+ P +E EE+ E Sbjct: 563 Q-RMEQEAE-RRRQPQIKQEPESEEEEEEKQE 592 Score = 26.9 bits (58), Expect = 4.9 Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 3/116 (2%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 +++ + L + DPDA + E QEA R+ + + K + E E E +Q +K Sbjct: 544 EEIRQRLLAEGHPDPDAELQRME-QEAERRRQPQIKQEPESEEEEEE--KQEKEEKREEP 600 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQ 129 +EE E E + ++ + P + G DES +I + P Q Sbjct: 601 MEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQ 656 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 39.7 bits (91), Expect = 7e-04 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91 ++EE RQ+ LR+ ++ER+ + K E E E + Q +K++ E E Q E E Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQ------RLKREHEEERREQELAEEEQE 691 Query: 92 GSLTRPKKAIP 102 + R K IP Sbjct: 692 QARERIKSRIP 702 Score = 36.6 bits (83), Expect = 0.006 Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 8/83 (9%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER------ 78 E++ + ++E +Q+ R EEER+ ++ K+E E +Q R++ +++EER Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520 Query: 79 --EAEAQAAMEANSEGSLTRPKK 99 E E + SE L R ++ Sbjct: 521 RQEEEERLQQRLRSEQQLRREQE 543 Score = 36.2 bits (82), Expect = 0.008 Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84 E+ ++EE R++ LR+ +EER+ + + E E E Q +R + +++E RE + + Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE---QEEERREQQLRR 379 Query: 85 AMEANSEGSLTRPKK 99 + E L R ++ Sbjct: 380 EQQLRREQQLRREQQ 394 Score = 35.8 bits (81), Expect = 0.011 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 23 DEEKDPDAAKKEEER--QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 +E ++ +++EER Q+ R+ EEER+ + + E E E Q +R + ++++++ Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391 Query: 81 EAQAAME 87 E Q E Sbjct: 392 EQQLRRE 398 Score = 35.8 bits (81), Expect = 0.011 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 +E +D ++EE RQ+ L++ +EER + K E E E + Q R + +K++E E Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRLKRE-EVERLEQEERREQRLKREEPEEERR 630 Query: 83 QAAMEANSE 91 Q +++ + Sbjct: 631 QQLLKSEEQ 639 Score = 32.7 bits (73), Expect = 0.089 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 7/80 (8%) Query: 24 EEKDPDAAKKEEE-------RQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76 EE+ K+EEE R++ L++ +EER+ + K E ER R + ++++ Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602 Query: 77 EREAEAQAAMEANSEGSLTR 96 +RE + E E L R Sbjct: 603 KREEVERLEQEERREQRLKR 622 Score = 32.3 bits (72), Expect = 0.12 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 + L ++E++ K E+ER+E + E+E + + K E E E Q R K +K+ +E Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-RRKQQLKRDQE 481 Query: 78 RE 79 E Sbjct: 482 EE 483 Score = 32.3 bits (72), Expect = 0.12 Identities = 17/65 (26%), Positives = 35/65 (53%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91 +++EER+E L + EEE++ + + E + ++ RD+ +++E R+ + E E Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599 Query: 92 GSLTR 96 L R Sbjct: 600 QRLKR 604 Score = 32.3 bits (72), Expect = 0.12 Identities = 18/68 (26%), Positives = 35/68 (51%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 E ++ +++EER++ L + EEER+ + K E E ++ R++ ++EER + Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620 Query: 84 AAMEANSE 91 E E Sbjct: 621 KREEPEEE 628 Score = 31.2 bits (69), Expect = 0.26 Identities = 17/94 (18%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 14 KDMGKMLGGDEEKDPDAAKKE--------EERQEALRQAEEERKAKYAKMEAEREAVRQG 65 +D+ +LG +E+D + ++ E ++ R+ ++E K + K + E++ +R+ Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324 Query: 66 IRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99 +K ++ + + E + ++ E L R ++ Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358 Score = 30.4 bits (67), Expect = 0.44 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 7/100 (7%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 ++LG + EK ++++ R+E Q EEE+ + ERE R+ ++ KK E Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQ-----LLREEREKRRRQEWERQYRKKDEL 1026 Query: 78 REAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117 ++ E Q E + L ++ +E+++E+E +L Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYRE--EEELQQEEEQLL 1064 Score = 28.9 bits (63), Expect = 1.3 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 32 KKEEER---QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEA 88 K+EEER QE R+ +E R+ + + E + ++ R++ +++EE E Q E Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368 Query: 89 NSE 91 E Sbjct: 369 EEE 371 Score = 28.9 bits (63), Expect = 1.3 Identities = 15/61 (24%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVR-QGIRDKYGIKKKEEREAEA 82 E ++ +++EER+E + +EE + ++ +E++ R Q R + +K++EE+ E Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560 Query: 83 Q 83 + Sbjct: 561 E 561 Score = 28.9 bits (63), Expect = 1.3 Identities = 12/48 (25%), Positives = 28/48 (58%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79 +K E ++ LR+ E ERK + + R+ + + R++ ++++ E+E Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738 Score = 28.1 bits (61), Expect = 2.2 Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 24 EEKDPDAAKKEEERQEALR--QAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 E ++ + ++ R++ LR Q EE R+ + + E + +Q R + +++++E E Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348 Query: 82 AQAAMEANSE 91 Q E E Sbjct: 349 QQLRREQEEE 358 Score = 28.1 bits (61), Expect = 2.2 Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 9/86 (10%) Query: 23 DEEKDPDAAKKEEE-------RQEALRQAEEERKAKYAKMEAEREAVRQGIR--DKYGIK 73 ++E+ K+E+E R+E + E+ER+ + K + E E + ++ ++ + Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKK 99 ++E RE + + E E L R ++ Sbjct: 499 QQERREQQLRREQEERREQRLKRQEE 524 Score = 28.1 bits (61), Expect = 2.2 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 10/85 (11%) Query: 24 EEKDPDAAKKEEER---------QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKK 74 EE+ K++EE ++ LR+ +EER+ + K E E+ + Q R++ ++ Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR-LEQERREQRLKRE 570 Query: 75 KEEREAEAQAAMEANSEGSLTRPKK 99 +EER + E + L R ++ Sbjct: 571 QEERRDQLLKREEERRQQRLKREQE 595 Score = 28.1 bits (61), Expect = 2.2 Identities = 14/92 (15%), Positives = 41/92 (44%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 +EE+ ++ ER++ L+ EEE + + + + + G+++ ++ +E+ + Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + + E R P +++ +E + Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904 Score = 27.7 bits (60), Expect = 2.9 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 17/121 (14%) Query: 6 KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65 K AL + ++L +EE+ + EER++ RQ +E + + +++ E E + + Sbjct: 892 KPALQEQLRKEQQLLQEEEEE-----LQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946 Query: 66 IRDK---------YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 R+K Y KK +++ E E R KK +E+++E+E + Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE---EELQQEEEQL 1003 Query: 117 L 117 L Sbjct: 1004 L 1004 Score = 27.7 bits (60), Expect = 2.9 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 8/76 (10%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAK--------YAKMEAEREAVRQGIRDKYGIKKK 75 +E++ ++EE +QE + EER+ + Y K E ++ Q +R++ +++ Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103 Query: 76 EEREAEAQAAMEANSE 91 +ERE + + E E Sbjct: 1104 QERERQCREEEELQQE 1119 Score = 27.3 bits (59), Expect = 3.8 Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 EE++ + K+E ++ + +EE + +++ E E +R+ R + + ER+ E Q Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL----RRERQEEEQ 295 Query: 84 AAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 E L R ++ +E E+ E Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQE 326 Score = 26.9 bits (58), Expect = 4.9 Identities = 12/56 (21%), Positives = 30/56 (53%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAME 87 ++EE R++ LR+ +EE + + ++ Q +R + ++++++ E Q E Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410 Score = 26.9 bits (58), Expect = 4.9 Identities = 19/86 (22%), Positives = 41/86 (47%), Gaps = 9/86 (10%) Query: 23 DEEKDPDAAKKEEERQE--ALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 +E + ++++ER+E R+ EEER + K E E E Q + ++ + +E ++ Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699 Query: 81 -------EAQAAMEANSEGSLTRPKK 99 + ++ +A +RP+K Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRK 725 Score = 26.9 bits (58), Expect = 4.9 Identities = 20/100 (20%), Positives = 49/100 (49%), Gaps = 7/100 (7%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 ++L + EK ++ + R+E Q EEE+ + + + R+ + + R++ ++++EE Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151 Query: 78 REAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117 + + E L R + +E+++E+E +L Sbjct: 1152 QLLREEPEKRRRQE--LERQYRE-----EEELQQEEEQLL 1184 Score = 26.6 bits (57), Expect = 6.4 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 2/53 (3%) Query: 33 KEEERQEALRQAEEERKAKYAKMEAER--EAVRQGIRDKYGIKKKEEREAEAQ 83 +EEER +Q EE+R+ + +AE E RQ + + ++++ ER+ A+ Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801 Score = 26.6 bits (57), Expect = 6.4 Identities = 19/95 (20%), Positives = 51/95 (53%), Gaps = 9/95 (9%) Query: 25 EKDPDAAKKEEER--QEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 ++D + + +E+R Q+ Q EEERK + + A + A+++ +R + + ++EE E + Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA-KPALQEQLRKEQQLLQEEEEELQR 915 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117 + + + + ++ +++++E+E +L Sbjct: 916 EEREKRRRQEQERQYREE------EQLQQEEEQLL 944 Score = 26.6 bits (57), Expect = 6.4 Identities = 21/87 (24%), Positives = 45/87 (51%), Gaps = 4/87 (4%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREA-VRQGIRDKYGIKKKEEREAEAQAAMEANS 90 ++ +ER+ R+ EE ++ + + ERE RQ + +Y +K+EE + E + + Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY--RKEEELQQEEEQLLREEP 1098 Query: 91 EGSLTRPKKAIPPGCGDEVEEEDESIL 117 E R ++ +E+++E+E +L Sbjct: 1099 E-KRRRQERERQCREEEELQQEEEQLL 1124 Score = 26.2 bits (56), Expect = 8.4 Identities = 12/56 (21%), Positives = 29/56 (51%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEERE 79 E+++ +E +++E EEE K + + ERE Q + ++ ++++E + Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 38.9 bits (89), Expect = 0.001 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 D E+D D E +E R E+ER+ + + E ERE R+ ++ ERE E Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERE---------RERERERER 774 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + A E + E R + G D E+ +E Sbjct: 775 ERARERDKERERQRDWEDKDKGRDDRREKREE 806 Score = 35.8 bits (81), Expect = 0.011 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKM-------EAEREAVRQGIRDKYGIKKK 75 + E+D + K+ E +E R+ E ER+ + + + ERE R+ R+K +++ Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753 Query: 76 EEREAEAQAAMEANSEGSLTRPK 98 EERE E + E E R + Sbjct: 754 EERERERERERERERERERERER 776 Score = 33.1 bits (74), Expect = 0.069 Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE---ERE 79 D+ +D A +++ ER+ + E + + + E ERE R+ R++ ++KE ER+ Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERD 728 Query: 80 AEAQAAMEANSEGSLTRPKK 99 + E E R K+ Sbjct: 729 RDRDHDRERERERERDREKE 748 Score = 32.3 bits (72), Expect = 0.12 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAK-MEAEREAVRQGIRDKYGIKKKEEREAE 81 + E + + A++ E +E R E +R + + E ERE R+ R++ +++ ERE E Sbjct: 704 ERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE 763 Query: 82 AQAAMEANSEGSLTRPK 98 + E E R + Sbjct: 764 RERERERERERERARER 780 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 15/86 (17%) Query: 21 GGDEEKDPDAAKKE-------EERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 G ++E + D ++E + R E R+ + ER+ + ERE R+ RD+ + Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERER-----DRERERERERERDR---E 700 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKK 99 +++ERE E + A E E R ++ Sbjct: 701 REKERELERERAREREREREKERDRE 726 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 8/94 (8%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAER------EAVRQGIRDKYGIKKKEEREAEAQAA 85 +K E ++ + R E+E K K + ++ +R E+ R +D G + E+RE +A Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953 Query: 86 MEANSEGSLTRPKKAIPPGCGDEVEEEDESILDT 119 E + + KK I D+V E +I T Sbjct: 954 DENKKKAKI--QKKPIKKKKEDDVGIERGNIETT 985 >gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo sapiens] Length = 475 Score = 38.5 bits (88), Expect = 0.002 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 16/88 (18%) Query: 11 GATKDMGKM---LGGDEEKDPDAAKK-EEERQEALRQAEEERKAKYAKMEAEREAVRQGI 66 G +K GKM + D E + A +K EEE +E L + +E+K + AK+ E+ Sbjct: 37 GKSKGGGKMNEEISSDSESESLAPRKPEEEEEEELEETAQEKKLRLAKLYLEQ------- 89 Query: 67 RDKYGIKKKEEREAEAQAAMEANSEGSL 94 ++++EE +AEA+A E G L Sbjct: 90 -----LRQQEEEKAEARAFEEDQVAGRL 112 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 38.5 bits (88), Expect = 0.002 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 5/81 (6%) Query: 23 DEEKDPDAAKKEEERQ---EALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE-ER 78 D ++D D +KE ERQ + R+ E +R+ + K E +RE R+ R++ +++E ER Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETE-RKRERQRERERERERNRKRERERERER 325 Query: 79 EAEAQAAMEANSEGSLTRPKK 99 E E Q E + E R +K Sbjct: 326 ERERQRETERDREKERERKRK 346 Score = 37.7 bits (86), Expect = 0.003 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 13/89 (14%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKA------------KYAKMEAEREAVRQGIRDKY 70 + +K+ + K +ER+E RQ E+E K + + E E E RQ R++ Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER- 232 Query: 71 GIKKKEEREAEAQAAMEANSEGSLTRPKK 99 ++K ERE E QA E SE R K+ Sbjct: 233 DRQRKTEREREKQAERERASERETERDKE 261 Score = 34.3 bits (77), Expect = 0.031 Identities = 16/64 (25%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERK-----AKYAKMEAEREAVRQGIRDKYGIKKKEE 77 + +++ + +++E ++ RQ E +R+ + + +AERE R+ RD+ +++EE Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387 Query: 78 REAE 81 RE + Sbjct: 388 RERD 391 Score = 32.3 bits (72), Expect = 0.12 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAK-MEAEREAVRQGIRDKYGI---KKKEEREA 80 E+D + +K E ++E R+ E RK + + E ERE R+ RD+ K+K + E Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351 Query: 81 EAQAAMEANSEG 92 + + + EG Sbjct: 352 DRERNRQTGREG 363 Score = 31.6 bits (70), Expect = 0.20 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 D E+D + E ++A R+ ER+ + K E ERE R RD+ +++ + + + Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDK-ERERERDRDRDRDRRQKERERQTDRKR 287 Query: 83 QAAMEANSEGSLTRPKK 99 Q E + E R ++ Sbjct: 288 QRRTERDRETERKRERQ 304 Score = 31.2 bits (69), Expect = 0.26 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE-----E 77 D E++ ++ + E R+ E ER + A+ ERE R R K ++ E + Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411 Query: 78 REAEAQAAMEANSEGSLTRPK 98 RE E Q E + E R + Sbjct: 412 RETEKQREREKDRESERGRER 432 Score = 30.4 bits (67), Expect = 0.44 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 10/95 (10%) Query: 6 KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65 ++ LG A KD G D E++ K+ E R+E RQ E E K E RE R Sbjct: 39 RRGLGQAHKDAD---GDDRERNRQ--KERERRREK-RQTERETD---RKRERRREKDRHR 89 Query: 66 IRDKYGIKKKE-EREAEAQAAMEANSEGSLTRPKK 99 RD++ ++++ E+E E Q E + + R ++ Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124 Score = 30.4 bits (67), Expect = 0.44 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 KD + E+ D +KE ERQ + + K + + E ERE R+G R + + Sbjct: 85 KDRHRKRDRHRERQRDR-EKERERQTDRERDRQREKERNRQKERERETEREGERGR-DRQ 142 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKK 99 +RE E Q E E R ++ Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQ 168 Score = 30.4 bits (67), Expect = 0.44 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 15/88 (17%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE------ 76 + E+ DA K+ E + + RQ + ER + E ERE RQ R++ ++KE Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQ---KEREREKNRQERRERERQREKENKTEDR 204 Query: 77 ------EREAEAQAAMEANSEGSLTRPK 98 ERE E + E + R + Sbjct: 205 HSERGRERERERETETETERKRQTDRER 232 Score = 29.3 bits (64), Expect = 0.99 Identities = 17/86 (19%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 ++ K + + + + +E +E R + +R+ K + + +R+ R+ RD+ + Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKK 99 K+ ER+ E + E N + R ++ Sbjct: 300 KR-ERQRERERERERNRKRERERERE 324 Score = 29.3 bits (64), Expect = 0.99 Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84 + + D + + +E RQAE ER E ERE RQ R++ +++ +R+ + Q Sbjct: 348 QTEMDRERNRQTGREGRRQAERER-------ERERERDRQSARERE--ERERDRDRDRQK 398 Query: 85 AMEANSE 91 E +E Sbjct: 399 ERERQTE 405 Score = 28.9 bits (63), Expect = 1.3 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 6/71 (8%) Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 G D + D ++E ERQ + E + + + + ER ++ R+K ++E RE Sbjct: 138 GRDRQTD---GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK---NRQERRER 191 Query: 81 EAQAAMEANSE 91 E Q E +E Sbjct: 192 ERQREKENKTE 202 Score = 27.7 bits (60), Expect = 2.9 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 23 DEEKDPDAAK-KEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKK-EEREA 80 + E+D D + KE ERQ + + K + E +RE+ R R + K+K ER+ Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446 Query: 81 EAQAAMEANSE 91 E Q +A + Sbjct: 447 ERQTDRQAGRQ 457 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 38.1 bits (87), Expect = 0.002 Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 2/74 (2%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 K+ K + K+ + +KE E+Q R+ +E RK K K + ER+ ++G R++ K Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK--QRGRRERKKKK 118 Query: 74 KKEEREAEAQAAME 87 +++ERE E + E Sbjct: 119 ERKERERENKQRRE 132 Score = 36.2 bits (82), Expect = 0.008 Identities = 23/86 (26%), Positives = 40/86 (46%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 K+ K EK+ KKE++++E ++ ERK K + E ERE ++ R + + Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKK 99 KK+ R+ + E + KK Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKK 165 Score = 35.0 bits (79), Expect = 0.018 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84 +++ + K+ ER++ R+ E+ERK + K E ++ R+ R K +K++ERE + + Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE--RGKERERKRKEREKQRKE 88 Query: 85 AMEANSEGSLTRPKK 99 E KK Sbjct: 89 RREKERRKRKKEKKK 103 Score = 32.7 bits (73), Expect = 0.089 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 22 GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 G E+ +KE ER+ +Q E ++ K K + +E R+ R K K+K+ ++ E Sbjct: 110 GRRERKKKKERKEREREN--KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167 Query: 82 AQAAMEAN 89 + E N Sbjct: 168 REKKRERN 175 Score = 31.6 bits (70), Expect = 0.20 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 22 GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 G E+ KKEE ++ R +E +K + K ER+ R+ R +KK+ER+ + Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER-----RKKKERKKD 208 Query: 82 AQAAMEANSE 91 + + +S+ Sbjct: 209 RKTDRQTDSQ 218 Score = 30.8 bits (68), Expect = 0.34 Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER--EA 80 + E +K ++R++ R+ E +R+ + K E +R+ ++ R+K + ++ER E Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183 Query: 81 EAQAAMEANSEGSLTRPKK 99 E + E E R KK Sbjct: 184 ERKERRERKKERKKERRKK 202 Score = 29.6 bits (65), Expect = 0.76 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 6/78 (7%) Query: 25 EKDPDAAKKEEERQEALRQAE---EERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 E+ +K++ R+E R+ E ERK K K E ERE R+ R++ KK+ ER+ Sbjct: 132 ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE-EREKKRE--RNRKERKKERERKER 188 Query: 82 AQAAMEANSEGSLTRPKK 99 + E E + +K Sbjct: 189 RERKKERKKERRKKKERK 206 Score = 28.9 bits (63), Expect = 1.3 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 E ++ + K+E E++ R+ E +K K + + ER R+ R + ++KE RE E Sbjct: 39 ERREREKRKREREKE---RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93 Score = 27.7 bits (60), Expect = 2.9 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI-KKKEEREAE 81 ++E+ + KKE+++++ R+ +ER+ K + E +R+ R+ R K KKK ER+ Sbjct: 51 EKERKRERGKKEKKKRKK-RERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR 109 Query: 82 AQAAMEANSE 91 + + E Sbjct: 110 GRRERKKKKE 119 Score = 26.9 bits (58), Expect = 4.9 Identities = 14/76 (18%), Positives = 35/76 (46%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 +E++ + ++ E +++ R+ + ++ K K +RE R+ + + KK+E E + Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180 Query: 84 AAMEANSEGSLTRPKK 99 E + +K Sbjct: 181 KERERKERRERKKERK 196 >gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo sapiens] Length = 747 Score = 38.1 bits (87), Expect = 0.002 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 11/113 (9%) Query: 6 KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQG 65 +Q LG +D + GDE P + ++ E ++ K+K A + ER V+ Sbjct: 146 EQGLGKREEDEPEERSGDET--PGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVK-- 201 Query: 66 IRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118 ++++E++ +A E E +R K +PP + EEED+++++ Sbjct: 202 -------RQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVN 247 Score = 28.1 bits (61), Expect = 2.2 Identities = 14/27 (51%), Positives = 20/27 (74%), Gaps = 3/27 (11%) Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEE 47 GGDEE+D + +EEE +EAL + E+E Sbjct: 72 GGDEEEDEE---EEEEDEEALLEDEDE 95 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 38.1 bits (87), Expect = 0.002 Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 3/73 (4%) Query: 27 DPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAM 86 + +A K+EEER+ RQ EE++K + + E ++ ++ +K+K+E+E + +A + Sbjct: 448 EEEARKQEEERK---RQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMI 504 Query: 87 EANSEGSLTRPKK 99 E E + T+ ++ Sbjct: 505 EKQKEAAETKARE 517 Score = 33.1 bits (74), Expect = 0.069 Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK--YGIKKKEEREAE 81 +++ + + E+E Q+ L + E +RKA+ ++ E EA +Q K KKK+E E + Sbjct: 414 QKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEK 473 Query: 82 AQAAMEA 88 +A EA Sbjct: 474 RKAGEEA 480 Score = 32.3 bits (72), Expect = 0.12 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 10/105 (9%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 K G ++ K + AK++ E + L++ +E+ K + A +E ++EA R+ + E Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526 Query: 78 REAEAQAAME-----ANSEGSLTRPKKA-IPPGCGDEVEEEDESI 116 + Q E + + R +K+ +PP +V++ED + Sbjct: 527 EQIMLQIEQERLERKKRIDEIMKRTRKSDVPP----QVKKEDPKV 567 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 10/99 (10%) Query: 8 ALGGATKD---MGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAER----E 60 A GG ++ +GK G + A E+R++A Q E+E + + K E +R E Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435 Query: 61 AVRQGIRDKYGIK---KKEEREAEAQAAMEANSEGSLTR 96 R+ ++ ++ +K+E E + Q + EG R Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKR 474 Score = 29.3 bits (64), Expect = 0.99 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 20/126 (15%) Query: 24 EEKDPDAAKKE----EERQEALRQAEEERKAKYAKMEAEREAV---RQGIRDKYGIKKKE 76 EE++ A +E E+++ A Q E++ + ++ K+E +R+ R + +K K +E Sbjct: 63 EEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLRE 122 Query: 77 ERE-AEAQAAMEANSEGSLTRPKK-------AIPPGCGDEVEEEDESILDTVIKYLPGPL 128 E E EA L KK AI PG D ++ L T LP P Sbjct: 123 EEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACDK-----LSTSTMSLPKPT 177 Query: 129 QDMLKK 134 + + K Sbjct: 178 EPPMNK 183 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 37.7 bits (86), Expect = 0.003 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 13/98 (13%) Query: 23 DEEKDPDAAKKEEE--RQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 +EE++ + ++EEE +E R+ EEE + K + E E + ++ + K +++KEE Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307 Query: 81 EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118 E + M SL+ DE EEE+ L+ Sbjct: 2308 EKEEIMSEEETESLS-----------DEEEEEESCSLE 2334 Score = 37.0 bits (84), Expect = 0.005 Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 3/111 (2%) Query: 13 TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGI---RDK 69 +++M +L E+++ ++++EEER+E + EEE + + + + E E + + ++ Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 KKKE+++ E Q E E ++ +E EEE S+ + V Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337 Score = 31.2 bits (69), Expect = 0.26 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 10/101 (9%) Query: 22 GDEEKDPDAAKKEE--------ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 GD+ K+ +++ +E E E+L E++++ ++ E ERE + R++ ++ Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE--REEEEVR 2263 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 ++EE E + E E KK +EV+E++E Sbjct: 2264 EEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304 Score = 26.2 bits (56), Expect = 8.4 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERK-AKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 +EE + +KE++ E R +EE K A+ + A E R K ++++ + E Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE 1606 Query: 82 AQAAME 87 Q A E Sbjct: 1607 RQLAQE 1612 Score = 26.2 bits (56), Expect = 8.4 Identities = 23/114 (20%), Positives = 49/114 (42%), Gaps = 6/114 (5%) Query: 24 EEKDPDAAKKEE---ERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 E+K + +KEE E++E + + E E + + E + R+K +KK+++ + Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352 Query: 81 EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQDMLKK 134 + Q + + +P G G + +L + +K L +M +K Sbjct: 2353 QEQRRKSLRGRERVLSILRGVPHGKGRAIR---LGVLKSPLKKLMSTALEMKEK 2403 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 37.7 bits (86), Expect = 0.003 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 6/82 (7%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEER----- 78 EE++ K++E+R+E ++ E+++K K + E+E + + K KK+EE Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 Query: 79 -EAEAQAAMEANSEGSLTRPKK 99 E E + E EG + KK Sbjct: 80 EEEEEEKEEEEKEEGRRRKKKK 101 Score = 33.9 bits (76), Expect = 0.040 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 13 TKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGI 72 TK+ K +EE+ K++++++E R+ EEE + + K E E+E R+ + K Sbjct: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE-EKEEEEKEEGRRRKKKKKRR 104 Query: 73 KKKEERE 79 +K+EE E Sbjct: 105 RKEEEEE 111 Score = 33.1 bits (74), Expect = 0.069 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSE 91 KKE E E + EEE + + + E +E + K KKK+ +E E + E + Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKE------KRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 92 GSLTRPKKAIPPGCGDEVEEEDE 114 + KK +E EEE+E Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEE 83 Score = 29.3 bits (64), Expect = 0.99 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 9/91 (9%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 ++K ++ EE +E + E+E K K + E +E ++ + K K+KE+ E E + Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEKK 61 Query: 84 AAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + R KK +E EEE+E Sbjct: 62 RKRK--------RKKKKEEEEREEEEEEEEE 84 Score = 29.3 bits (64), Expect = 0.99 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 14/90 (15%) Query: 24 EEKDPDAAKKEEERQEALRQAE--EERKAKYAKM------------EAEREAVRQGIRDK 69 EE + +EEE +E R+ + E+RK K K E E++ R+ + K Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKK 99 +++EE E E + E E R KK Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 Score = 29.3 bits (64), Expect = 0.99 Identities = 11/47 (23%), Positives = 31/47 (65%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69 +EE++ + K+EEE++E R+ +++++ + + E +++ R+ + K Sbjct: 77 EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 28.9 bits (63), Expect = 1.3 Identities = 12/42 (28%), Positives = 28/42 (66%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64 +EE++ + +KEEE +E R+ ++++K + + E E++ R+ Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 Score = 28.5 bits (62), Expect = 1.7 Identities = 14/52 (26%), Positives = 28/52 (53%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKK 74 +EE++ + ++EEE++E ++ RK K + E E ++ R + KK Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 37.7 bits (86), Expect = 0.003 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKY-AKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 EE++ A++E R +A QAEE R+ + A++E R + R +K++EE EAE Sbjct: 309 EERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEG 368 Query: 83 QAAMEANSEGSLTRPKKAI-PPGCGDEVEEEDE 114 +E E + P +A+ G G EE++ Sbjct: 369 WEELE-QQEAEVQGPPEALEETGEGRRGAEEED 400 >gi|55741655 anoctamin 8 [Homo sapiens] Length = 1232 Score = 37.4 bits (85), Expect = 0.004 Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 17/103 (16%) Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 GG+E P K+E+E E EEE E E E G+ D G++ K+ A Sbjct: 570 GGEEGDGPPGGKEEDEDDEEEEDEEEE--------EDEEEGEEGGLLD-CGLRLKKVSFA 620 Query: 81 EAQAAMEAN--------SEGSLTRPKKAIPPGCGDEVEEEDES 115 E A EGS T +K + PG EE+DE+ Sbjct: 621 ERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEEDDEA 663 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 37.4 bits (85), Expect = 0.004 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 18/105 (17%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70 GA D + G EK+ + K+E E++E +AE E + AK E Sbjct: 542 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE-------------- 585 Query: 71 GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 KK EE+ E E ++ + +P+KA P VEE+ +S Sbjct: 586 --KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628 Score = 35.8 bits (81), Expect = 0.011 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 6/111 (5%) Query: 5 MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64 M++AL T+++ + +E+ +AA+++EE EA EEE AK + ++A V++ Sbjct: 469 MEEALTAITEELAVSM---KEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKE 522 Query: 65 GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 +K + +EE E E + A +E + + + G++ E E E+ Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573 Score = 32.7 bits (73), Expect = 0.089 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 24/107 (22%) Query: 23 DEEKDPDAAKK-------------EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69 + E++ AAKK E E++E Q EEE + + AK + E G +K Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----GGSEK 555 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 G +KEE E E + EA +EG K+ +VEE+ E + Sbjct: 556 EGSSEKEEGEQE-EGETEAEAEGEEAEAKEE------KKVEEKSEEV 595 Score = 27.7 bits (60), Expect = 2.9 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 +EEK+ A KEE+ ++ + ++ + K A+ + EAV + + +K E+E + Sbjct: 704 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK- 762 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 EG + +K G+ EE+ S Sbjct: 763 -------EEGKPLQQEKEKEKAGGEGGSEEEGS 788 Score = 27.7 bits (60), Expect = 2.9 Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 25/113 (22%) Query: 5 MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQ--------------------EALRQA 44 +K L TK+ GK L ++EK+ + E + E + Sbjct: 753 VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 812 Query: 45 EEERKAKYAKMEAEREAVRQGI-----RDKYGIKKKEEREAEAQAAMEANSEG 92 E+E K K + E E+ V G+ +K G K EE+ + + SEG Sbjct: 813 EQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865 Score = 26.2 bits (56), Expect = 8.4 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 6/57 (10%) Query: 34 EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANS 90 E + + QAEE K +YAK+ E ++K I+ +E AE + +++ S Sbjct: 278 ESHSDQNMHQAEEWFKCRYAKLTEAAE------QNKEAIRSAKEEIAEYRRQLQSKS 328 Score = 26.2 bits (56), Expect = 8.4 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 4/100 (4%) Query: 24 EEKDPDAAKK---EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 EEK K EE+ + + ++ E KAK ++ E + G +K+EE + Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 708 Query: 81 EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 +A E E +PK +P E ++E++ + V Sbjct: 709 VKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 747 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 37.4 bits (85), Expect = 0.004 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 18/105 (17%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70 GA D + G EK+ + K+E E++E +AE E + AK E Sbjct: 166 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE-------------- 209 Query: 71 GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 KK EE+ E E ++ + +P+KA P VEE+ +S Sbjct: 210 --KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252 Score = 35.8 bits (81), Expect = 0.011 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 6/111 (5%) Query: 5 MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64 M++AL T+++ + +E+ +AA+++EE EA EEE AK + ++A V++ Sbjct: 93 MEEALTAITEELAVSM---KEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKE 146 Query: 65 GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 +K + +EE E E + A +E + + + G++ E E E+ Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197 Score = 32.7 bits (73), Expect = 0.089 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 24/107 (22%) Query: 23 DEEKDPDAAKK-------------EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69 + E++ AAKK E E++E Q EEE + + AK + E G +K Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----GGSEK 179 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 G +KEE E E + EA +EG K+ +VEE+ E + Sbjct: 180 EGSSEKEEGEQE-EGETEAEAEGEEAEAKEE------KKVEEKSEEV 219 Score = 27.7 bits (60), Expect = 2.9 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 +EEK+ A KEE+ ++ + ++ + K A+ + EAV + + +K E+E + Sbjct: 328 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK- 386 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 EG + +K G+ EE+ S Sbjct: 387 -------EEGKPLQQEKEKEKAGGEGGSEEEGS 412 Score = 27.7 bits (60), Expect = 2.9 Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 25/113 (22%) Query: 5 MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQ--------------------EALRQA 44 +K L TK+ GK L ++EK+ + E + E + Sbjct: 377 VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 436 Query: 45 EEERKAKYAKMEAEREAVRQGI-----RDKYGIKKKEEREAEAQAAMEANSEG 92 E+E K K + E E+ V G+ +K G K EE+ + + SEG Sbjct: 437 EQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489 Score = 26.2 bits (56), Expect = 8.4 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 4/100 (4%) Query: 24 EEKDPDAAKK---EEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 EEK K EE+ + + ++ E KAK ++ E + G +K+EE + Sbjct: 273 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 332 Query: 81 EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 +A E E +PK +P E ++E++ + V Sbjct: 333 VKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 371 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 37.4 bits (85), Expect = 0.004 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 10/94 (10%) Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA 80 GG+EE E E +E R+ EEE++ + K E E E V + G +KKEER Sbjct: 730 GGEEEHG------EGEEEEGDREEEEEKEGE-GKEEGEGEEVEGEREKEEGERKKEERAG 782 Query: 81 EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + + E EG ++ G G+E EE E Sbjct: 783 KEEKGEE---EGDQGEGEEEETEGRGEEKEEGGE 813 Score = 32.7 bits (73), Expect = 0.089 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 6/93 (6%) Query: 22 GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 G+ E++ K EEE +E + EEE E E E ++ G + EE E E Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEG------EGEGEDGEGEGEEEEGEWEGEEEEGE 963 Query: 82 AQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + E EG + G G+ EEE E Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996 Score = 31.6 bits (70), Expect = 0.20 Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 3/105 (2%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70 G + GK G EE++ + +EEE + + E E + K E E E + Sbjct: 816 GGEVEEGK--GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873 Query: 71 GIKKKEEREAEAQAAMEANSEGSLTRPK-KAIPPGCGDEVEEEDE 114 G + EE E E + E EG + + G G+ EEE E Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918 Score = 31.6 bits (70), Expect = 0.20 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 9/94 (9%) Query: 22 GDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 G+EE+ ++EE +E + E E + + E E V + + G + EE E E Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040 Query: 82 AQA-AMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + E EG R + E EEE+E Sbjct: 1041 EEGEEREKEGEGEENRRNR--------EEEEEEE 1066 Score = 30.8 bits (68), Expect = 0.34 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 5/104 (4%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70 G ++ G+ G+EE + + EEE E + E E + + + E E E +G ++ Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915 Query: 71 GIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + K E E E E EG + G G+ EEE E Sbjct: 916 EGEGKGEEEGE-----EGEGEGEEEEGEGEGEDGEGEGEEEEGE 954 Score = 30.4 bits (67), Expect = 0.44 Identities = 28/113 (24%), Positives = 46/113 (40%), Gaps = 10/113 (8%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKE---------EERQEALRQAEEERKAKYAKMEAEREA 61 G + G+ + G+ EK+ KKE EE + EEE + + + E E Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814 Query: 62 VRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + + G +++EE E E + E E ++ G G+E EE E Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEE-EGEGEEEEGEGEEEEGEGKGEEEGEEGE 866 Score = 30.0 bits (66), Expect = 0.58 Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 5/106 (4%) Query: 12 ATKDMGKMLGGDEE--KDPDAAKKEEERQEALRQAEEER---KAKYAKMEAEREAVRQGI 66 A K+ K G+E+ K+ + ++E QE EEE + + E E E +G Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756 Query: 67 RDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEE 112 + G + + ERE E + G + ++ G G+E E E Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802 Score = 29.6 bits (65), Expect = 0.76 Identities = 16/71 (22%), Positives = 36/71 (50%) Query: 11 GATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY 70 G ++ G++ G E ++ + +EEE +E + E+E + + + E E +G + Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072 Query: 71 GIKKKEEREAE 81 G ++ E ++ E Sbjct: 1073 GEEENERQDGE 1083 Score = 29.3 bits (64), Expect = 0.99 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Query: 10 GGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDK 69 G ++ G+ G +EE + + ++ E +E + EEE + + + E E E ++ Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE-VEGEVEGEEGEGEGEEE 1037 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118 G ++ EERE E + E R ++ G E EE+ D Sbjct: 1038 EGEEEGEEREKEGE-----GEENRRNREEEEEEEGKYQETGEEENERQD 1081 >gi|13027602 DDRGK domain containing 1 [Homo sapiens] Length = 314 Score = 37.4 bits (85), Expect = 0.004 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 6/98 (6%) Query: 33 KEEERQEALRQAEEERKAKYAKMEAEREAV----RQGIRDKYGIKKKEEREA-EAQAAME 87 +E++ ++A R+AEE + + ++E++REA + +R + K++EER+A E QA E Sbjct: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQRE 185 Query: 88 ANSEGSLTRPKKAIPPGCGDEV-EEEDESILDTVIKYL 124 L G G+ + EE+ +S L I Y+ Sbjct: 186 HEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYI 223 Score = 28.1 bits (61), Expect = 2.2 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 11/68 (16%) Query: 32 KKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE----EREAEAQAAME 87 KKEEER + +EE + K + +A+RE ++Y +K KE E E + E Sbjct: 157 KKEEERLRLEEEQKEEEERKAREEQAQRE------HEEY-LKLKEAFVVEEEGVGETMTE 209 Query: 88 ANSEGSLT 95 S+ LT Sbjct: 210 EQSQSFLT 217 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 37.4 bits (85), Expect = 0.004 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Query: 24 EEKDPDAAK--KEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAE 81 +++D + AK K +E++E +++ K K ++ + E E V+ + G+ E +AE Sbjct: 241 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300 Query: 82 AQAAMEANSEGSLTRPKKAIPPGCGDEVEEE 112 A E ++EG + K G +E E+E Sbjct: 301 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKE 331 Score = 33.5 bits (75), Expect = 0.052 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 15/89 (16%) Query: 14 KDMGKMLGGDEEKDPDAAK---------------KEEERQEALRQAEEERKAKYAKMEAE 58 KD K G EEK+ + K K +E +E ++ EEER + ++EA+ Sbjct: 316 KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAK 375 Query: 59 REAVRQGIRDKYGIKKKEEREAEAQAAME 87 R+ + ++K KK++E+E + + E Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKE 404 Score = 30.8 bits (68), Expect = 0.34 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 5 MKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQ 64 M++AL ++ + +EE+ + E +R+E R +E+R+ K K + +E +++ Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403 Query: 65 GIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKK 99 K K + E A A+A ++ + P K Sbjct: 404 --EGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 24/105 (22%) Query: 23 DEEKDPDAAKKEEERQ---------EALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 ++E+ P + EEE EA+ EE K + K+ E V++ ++ + Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE---VKENPEEEEEEE 538 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILD 118 ++EE + E++ E E G E +EEDE + D Sbjct: 539 EEEEEDEESEEEEEEEGESE------------GSEGDEEDEKVSD 571 Score = 28.9 bits (63), Expect = 1.3 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQA 84 E++ + ++EEE +E+ + EEE +++ ++ + E E V + KK +E + + Sbjct: 532 EEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDS 591 Query: 85 AMEANSEGSLTRPKKA 100 E +S+ T+ ++A Sbjct: 592 --EYDSDDDRTKEERA 605 Score = 27.3 bits (59), Expect = 3.8 Identities = 15/69 (21%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAK---YAKMEAEREAVRQGIRDKYGIKKKEERE 79 +++ + D KK++++++ ++ +E+ K K A ++A +EA+ + ++ K++EE Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365 Query: 80 AEAQAAMEA 88 + +EA Sbjct: 366 IKRLEELEA 374 Score = 26.2 bits (56), Expect = 8.4 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 21 GGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEA----EREAVRQGIRDKYGIKKKE 76 G ++KD K E+E +E ++ + A EA + E RQ ++ IK+ E Sbjct: 311 GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370 Query: 77 EREAE 81 E EA+ Sbjct: 371 ELEAK 375 >gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sapiens] Length = 1101 Score = 37.4 bits (85), Expect = 0.004 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 14/106 (13%) Query: 21 GGDE---EKDPDAAKKEEERQEA--------LRQAEEERKAKYAKMEAEREAVRQGIRDK 69 GGDE EK+ + ++E+E++E L Q +E + K E ++ +G+R+ Sbjct: 738 GGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVRED 797 Query: 70 YGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDES 115 + K +RE A + +G +R +A G EV +E ES Sbjct: 798 ---EDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES 840 Score = 34.3 bits (77), Expect = 0.031 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 14/121 (11%) Query: 6 KQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEA---------LRQ-AEEERKAKYAKM 55 KQA G D+ + G E +A K E+R EA LR+ + EE +AK K Sbjct: 661 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS 720 Query: 56 EAEREA---VRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGC-GDEVEE 111 + +++A +G+ + G + +E+E E + + E + + + G D+V E Sbjct: 721 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE 780 Query: 112 E 112 E Sbjct: 781 E 781 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 37.0 bits (84), Expect = 0.005 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 ++ +M+ EEK + +K E++E +R+ EE+ + + KM+ + E +R+ G + Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687 Query: 74 KKEEREAEAQAAMEANSEGSLTRPKKAIPPGCG-DEVEEEDESILD 118 +K + E E G + G +E+ E++E I D Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733 Score = 32.0 bits (71), Expect = 0.15 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 10/92 (10%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 D+E+ ++ ER++ +R+ EE + + KM+ + E +R+ +EE+ E Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQ 600 Query: 83 QAAMEANSEGSLTRPKKAIPPGCGDEVEEEDE 114 + M+ E + +K D+++E++E Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632 Score = 31.6 bits (70), Expect = 0.20 Identities = 18/77 (23%), Positives = 41/77 (53%), Gaps = 3/77 (3%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYG-- 71 ++ + + G EEK + +K + ++E +R+ EE+ + + KM + E + +G Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 722 Query: 72 -IKKKEEREAEAQAAME 87 +++KEER + + M+ Sbjct: 723 EMREKEERIRDQKEKMQ 739 Score = 29.3 bits (64), Expect = 0.99 Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEA 82 ++EK+ +KE Q+ LR+ EE+ + + KM + E +R+ + + ++EER E Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQ 343 Query: 83 QAAMEANSE 91 + M + Sbjct: 344 EKQMREQEQ 352 Score = 28.9 bits (63), Expect = 1.3 Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEE 77 K + E+K D ++ E+ E LR+ +EER + KM + E +++ R I+++E+ Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEEER----IREREK 399 Query: 78 REAEAQAAMEANSE 91 + E + M E Sbjct: 400 KMREEEETMREQEE 413 Score = 28.5 bits (62), Expect = 1.7 Identities = 17/78 (21%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 ++ K + +EE + +K +E++E +R+ EE+ + KM+ + E + + +K + Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ-EEKMWEQ 621 Query: 74 KKEEREAEAQAAMEANSE 91 ++E++ E + M E Sbjct: 622 EEEDKMQEQEEMMWEQEE 639 Score = 28.5 bits (62), Expect = 1.7 Identities = 22/104 (21%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Query: 18 KMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKY-----GI 72 KM +E+ K E+ ++ Q EE++ + +M E+E Q +K + Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655 Query: 73 KKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 +++EE+ E + M+ E + +K G +++ E++E + Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKM--QGQEEKMREQEEKM 697 Score = 27.7 bits (60), Expect = 2.9 Identities = 16/71 (22%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREA----VRQGIRDKYGIKKKEEREA 80 E+D +KEE +E + ++E K + K E+E + +R++ ++++E++ Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570 Query: 81 EAQAAMEANSE 91 E + M E Sbjct: 571 EEEEMMREQEE 581 Score = 27.3 bits (59), Expect = 3.8 Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 24 EEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQ 83 E+K D ++ E+ E LR+ +EER + KM + E +R+ + + KK ++E + + Sbjct: 499 EQKMWDQEERMWEQDERLRE-KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557 Query: 84 AAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 R ++ + ++++E++E + Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKM 590 Score = 26.9 bits (58), Expect = 4.9 Identities = 15/74 (20%), Positives = 37/74 (50%) Query: 14 KDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIK 73 ++ K + EEK ++ E++ +R+ EE+ + + ++ + + +R+ ++ K Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303 Query: 74 KKEEREAEAQAAME 87 K E+E + Q E Sbjct: 304 KLREQEEQMQEQEE 317 >gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] Length = 871 Score = 37.0 bits (84), Expect = 0.005 Identities = 22/100 (22%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 17 GKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76 G LG E K D +K+E+ ++A + + K K ++ + ++E ++ + KK Sbjct: 292 GAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSS 349 Query: 77 EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESI 116 ++ + ++ EGS++ + G +E +EE E++ Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEAL 389 Score = 30.4 bits (67), Expect = 0.44 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 25 EKDPDAAKKEEERQEALRQAEEERKAKYAKMEA--EREAVRQGIRDKYGIKKKEEREAEA 82 E D D +K+E+ ++ +++ ++R K++ ++ E + G ++E+ EAEA Sbjct: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEA 388 Query: 83 QAAMEANSEGSLTRPKKAIPPGC 105 E E +PK A C Sbjct: 389 LKEKEKPKEEEWEKPKDAAGLEC 411 Score = 27.7 bits (60), Expect = 2.9 Identities = 12/45 (26%), Positives = 26/45 (57%) Query: 10 GGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAK 54 G + D G + + E + A++E+E EAL++ E+ ++ ++ K Sbjct: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 >gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] Length = 872 Score = 37.0 bits (84), Expect = 0.005 Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 2/101 (1%) Query: 17 GKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKE 76 G LG E K D +K+E+ ++A + + K K ++ + ++E ++ + KK Sbjct: 292 GAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSS 349 Query: 77 EREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESIL 117 ++ + ++ EGS++ + G +E +EE E L Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390 Score = 26.9 bits (58), Expect = 4.9 Identities = 11/39 (28%), Positives = 23/39 (58%) Query: 23 DEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREA 61 + E + ++ + EEE++EA +E+ K K + E ++A Sbjct: 369 ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.127 0.335 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,537,101 Number of Sequences: 37866 Number of extensions: 261422 Number of successful extensions: 5816 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 442 Number of HSP's successfully gapped in prelim test: 397 Number of HSP's that attempted gapping in prelim test: 2209 Number of HSP's gapped (non-prelim): 2833 length of query: 134 length of database: 18,247,518 effective HSP length: 91 effective length of query: 43 effective length of database: 14,801,712 effective search space: 636473616 effective search space used: 636473616 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.