Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 57242755
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
(971 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 1988 0.0
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 1980 0.0
gi|209364544 calsyntenin 2 [Homo sapiens] 1107 0.0
gi|42475534 calsyntenin 3 [Homo sapiens] 1024 0.0
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 66 1e-10
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 64 5e-10
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 64 5e-10
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 64 5e-10
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 64 5e-10
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 63 1e-09
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 62 3e-09
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 59 2e-08
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 57 6e-08
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 56 1e-07
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 55 2e-07
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 55 3e-07
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 55 3e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 55 4e-07
gi|11276081 protocadherin beta 8 precursor [Homo sapiens] 54 5e-07
gi|9256604 protocadherin beta 11 precursor [Homo sapiens] 54 7e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 53 1e-06
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 53 2e-06
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 52 2e-06
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 52 2e-06
gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapi... 52 2e-06
gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapi... 52 2e-06
gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapi... 52 2e-06
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 52 2e-06
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 52 2e-06
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 52 2e-06
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 1988 bits (5150), Expect = 0.0
Identities = 971/971 (100%), Positives = 971/971 (100%)
Query: 1 MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI 60
MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI
Sbjct: 1 MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI 60
Query: 61 ALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQA 120
ALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQA
Sbjct: 61 ALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQA 120
Query: 121 YDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDA 180
YDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDA
Sbjct: 121 YDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDA 180
Query: 181 DCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATED 240
DCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATED
Sbjct: 181 DCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATED 240
Query: 241 VLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHI 300
VLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHI
Sbjct: 241 VLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHI 300
Query: 301 GKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQA 360
GKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQA
Sbjct: 301 GKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQA 360
Query: 361 VRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFL 420
VRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFL
Sbjct: 361 VRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFL 420
Query: 421 FRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPL 480
FRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPL
Sbjct: 421 FRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPL 480
Query: 481 HPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA 540
HPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA
Sbjct: 481 HPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA 540
Query: 541 DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNS 600
DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNS
Sbjct: 541 DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNS 600
Query: 601 RQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEF 660
RQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEF
Sbjct: 601 RQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEF 660
Query: 661 ESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELN 720
ESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELN
Sbjct: 661 ESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELN 720
Query: 721 HEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKF 780
HEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKF
Sbjct: 721 HEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKF 780
Query: 781 KLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP 840
KLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP
Sbjct: 781 KLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP 840
Query: 841 HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTI 900
HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTI
Sbjct: 841 HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTI 900
Query: 901 TVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQ 960
TVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQ
Sbjct: 901 TVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQ 960
Query: 961 QLEWDDSTLSY 971
QLEWDDSTLSY
Sbjct: 961 QLEWDDSTLSY 971
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 1980 bits (5129), Expect = 0.0
Identities = 971/981 (98%), Positives = 971/981 (98%), Gaps = 10/981 (1%)
Query: 1 MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI 60
MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI
Sbjct: 1 MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI 60
Query: 61 ALDKDAPLRFA----------GEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCEL 110
ALDKDAPLRFA GEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCEL
Sbjct: 61 ALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCEL 120
Query: 111 QKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD 170
QKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD
Sbjct: 121 QKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD 180
Query: 171 SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAY 230
SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAY
Sbjct: 181 SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAY 240
Query: 231 DCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQ 290
DCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQ
Sbjct: 241 DCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQ 300
Query: 291 ATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSD 350
ATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSD
Sbjct: 301 ATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSD 360
Query: 351 QVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSL 410
QVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSL
Sbjct: 361 QVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSL 420
Query: 411 YVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHE 470
YVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHE
Sbjct: 421 YVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHE 480
Query: 471 PFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLA 530
PFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLA
Sbjct: 481 PFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLA 540
Query: 531 GLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDK 590
GLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDK
Sbjct: 541 GLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDK 600
Query: 591 AMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGV 650
AMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGV
Sbjct: 601 AMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGV 660
Query: 651 HHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTC 710
HHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTC
Sbjct: 661 HHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTC 720
Query: 711 EVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNW 770
EVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNW
Sbjct: 721 EVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNW 780
Query: 771 HARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFV 830
HARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFV
Sbjct: 781 HARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFV 840
Query: 831 DLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENE 890
DLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENE
Sbjct: 841 DLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENE 900
Query: 891 MDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQ 950
MDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQ
Sbjct: 901 MDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQ 960
Query: 951 GDPQNATRQQQLEWDDSTLSY 971
GDPQNATRQQQLEWDDSTLSY
Sbjct: 961 GDPQNATRQQQLEWDDSTLSY 981
>gi|209364544 calsyntenin 2 [Homo sapiens]
Length = 955
Score = 1107 bits (2864), Expect = 0.0
Identities = 527/958 (55%), Positives = 707/958 (73%), Gaps = 50/958 (5%)
Query: 28 AARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFD 87
AA+VNKHKPW+E +YHG++TEN++TV+LDPPL+ALDKDAP+ FAGEIC FKIHGQ +PF+
Sbjct: 34 AAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFE 93
Query: 88 AVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDV 147
AVV++K++GEG +R+K +DCELQK+Y+F IQAYDCG GP T KKSHKA VHIQV DV
Sbjct: 94 AVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDV 153
Query: 148 NEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDG 207
NE+AP FKE +YKA V EGK YDSIL+VEA+D DCSPQ+SQIC+YEI+T DVPF +D++G
Sbjct: 154 NEFAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNG 213
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPG 267
I+NTEKL+Y K+HQY++ VTAYDCG+K A +D LV++ +KP C PGWQ W RIEY+PG
Sbjct: 214 NIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG 273
Query: 268 TGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAEL 327
+G++ +FP+IHLETCD V+S+Q EL+T++IGKGCDR+TYSEKSL +LCGA++G +L
Sbjct: 274 SGSMPLFPSIHLETCDGAVSSLQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDL 333
Query: 328 LPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGP- 386
LPSPS + NWT GL D+ S+ +F+F+G Q ++PDG+V + + FTI++WM+HGP
Sbjct: 334 LPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKVPDGIVPKNLTDQFTITMWMKHGPS 390
Query: 387 --FGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVC 444
+KETILC+SDKT+MNRHHY+LYVH CRL+FL R+D + +RPAEFHWKL+Q+C
Sbjct: 391 PGVRAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHWKLDQIC 450
Query: 445 DEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLVVGACWQEFSGVEND 504
D+EWH+YV+NVEFP VTLY+DG ++EP+ VT D+P+HPS I QL VGACWQ
Sbjct: 451 DKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACWQ------GG 504
Query: 505 NETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSG 564
T+P QFF G+LA LT+R GK+ +KVI CL CKEGLD+ LE G
Sbjct: 505 EVTKP----------QFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINSLESLG 554
Query: 565 RGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEAT 624
+G++ +PSQ +L +EG+D+G +++A+Q +SY+NSRQFPT G+RRLK++S ++CF E
Sbjct: 555 QGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQCFGEDV 614
Query: 625 CISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEP 684
CIS+P VD YVMVLQ EP+I+L G HF R A++FES+ GV LFP+++I+ST + P
Sbjct: 615 CISIPEVDAYVMVLQAIEPRITLRGTDHFWRPAAQFESARGVTLFPDIKIVSTFAKTEAP 674
Query: 685 EGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSE 744
DP +S V EE++H+LD C++ V G +L+ QE LE++ + L Q+ ++ ++S
Sbjct: 675 GDVKTTDP---KSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLDATNST 731
Query: 745 LGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIH 804
G + GV +M+ YE+VLH +RYRNW SL R+F++ CSELNGRY SNEF +EV+++H
Sbjct: 732 AGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLEVSILH 791
Query: 805 --TANPMEHANHMAAQPQFV----HPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCV 858
+ EH NH+ QP F+ HPE RS + S +VVPS ATVVI++ V
Sbjct: 792 EDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQHS----------SVVPSIATVVIIISV 841
Query: 859 SFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEE 918
LVF++ +GV+R+R AH+ +++ + KE+EMDWDDSALTITVNPME +E E+E
Sbjct: 842 CMLVFVVAMGVYRVRIAHQHFIQETEAAKESEMDWDDSALTITVNPMEKHEGPGHGEDET 901
Query: 919 EEEEEEESEDGEEEDDITSAESESSEEEEGEQG-----DPQNATRQQQLEWDDSTLSY 971
E EEEEE+ EE+ +S+ S+ SEEEE E+G QN RQ QLEWDDSTL Y
Sbjct: 902 EGEEEEEA----EEEMSSSSGSDDSEEEEEEEGMGRGRHGQNGARQAQLEWDDSTLPY 955
>gi|42475534 calsyntenin 3 [Homo sapiens]
Length = 956
Score = 1024 bits (2647), Expect = 0.0
Identities = 495/947 (52%), Positives = 677/947 (71%), Gaps = 31/947 (3%)
Query: 15 LLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEI 74
LLLA LL + NKHKPW+E Y GIV ENDNTVLL+PPL ALDKDAPLR+AGEI
Sbjct: 8 LLLASLLASCS--CNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
Query: 75 CGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKK 134
CGF++HG VPF+AV++DK+TGEG+IR+KE +DCE QK+++FTIQAYDCG+GPDG N KK
Sbjct: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
Query: 135 SHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEI 194
SHKATVH++VNDVNE+APVF E+ Y+A V EGK YD ILRVEA+D DCSPQ+SQIC YEI
Sbjct: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEI 185
Query: 195 ITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPG 254
+TP+ PF +D DG I+NTEKL Y E YK TVTAYDCGKKRA +D V+I +KPTC P
Sbjct: 186 LTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPS 245
Query: 255 WQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSL 314
WQGWN RIEY PG G+LA+FP I LETCDEP+ ++QAT+EL+TSH+ KGCDRD YSE++L
Sbjct: 246 WQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERAL 305
Query: 315 HRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVS----- 369
+LCGAA G +LLP P + NWT GL DS ++ FNGTQAV++P G S
Sbjct: 306 RKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPSGLGSG 365
Query: 370 --VSPKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQ 423
S + FT+S WM+HG K +ETI+C++ + + HYSL VHGCR+ FL+
Sbjct: 366 PQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYW- 424
Query: 424 DPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPS 483
P E RP +F WKL QVCD+EWHHY LN+EFP+VTLY DG S +P + ++ +HP
Sbjct: 425 -PLLESA-RPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIHPP 482
Query: 484 KIETQLVVGACWQEFSGVE---NDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA 540
+ E L++GACW E E DN T+ + G L + +F G LAG ++RSG+L
Sbjct: 483 RREPALMIGACWTEEKNKEKEKGDNSTD----TTQGDPLSIHHYFHGYLAGFSVRSGRLE 538
Query: 541 DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNS 600
++VI+CLY C+EGLD + E G+G+++ +PSQ +LTLEG+D+ + A+QH++Y+N+
Sbjct: 539 SREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNT 598
Query: 601 RQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEF 660
+F TPG+R L++T+ +KCF+E +C+S+P V+GYV+VLQP+ P+I LSG HFAR A +F
Sbjct: 599 LRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDF 658
Query: 661 ESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELN 720
E + GV LFP+L+I +I+ +VE + D + TV ++ +S+EIVH+LD CE+++ G++L+
Sbjct: 659 EGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLD 718
Query: 721 HEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKF 780
E+ESL +D LQQ+G+E++++ +T GV+++ YEE+L RYR H +L RKF
Sbjct: 719 PERESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKF 778
Query: 781 KLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP 840
+L CSE+NGRY SNEF VEVNV+H+ N + H +H+ + QF+H H+ +++GH+LA+
Sbjct: 779 RLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASS 838
Query: 841 HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTM------RDQDTGKENEMDWD 894
H +++PS AT++IVVCV FLV M++LG+ RI + HRR K+ ++ WD
Sbjct: 839 HRNSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWD 898
Query: 895 DSALTITVNPMETYEDQHS--SEEEEEEEEEEESEDGEEEDDITSAE 939
DSALTI VNPME+Y+++ S + ++E+E+S D E D +S E
Sbjct: 899 DSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDE 945
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 66.2 bits (160), Expect = 1e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 22/168 (13%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+++ K+KLD E YS +QA D G S ATV+I ++DVN+ +PVF
Sbjct: 3396 GLVKVKKKLDRERVSGYSLLVQAVDSGIPA------MSSTATVNIDISDVNDNSPVFTPA 3449
Query: 158 SYKATVIEGKQY-DSILRVEAVDADC---SPQFSQICSYEIIT--PDVPFTVDKDGYIKN 211
+Y A + E K SIL++ D D P F S+ I++ + F +D G +++
Sbjct: 3450 NYTAVIQENKPVGTSILQLVVTDRDSFHNGPPF----SFSILSGNEEEEFVLDPHGILRS 3505
Query: 212 TEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI------KPTCTP 253
+ + +Y L V A D GK + +++ + KPT P
Sbjct: 3506 AVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIP 3553
Score = 58.9 bits (141), Expect = 2e-08
Identities = 75/289 (25%), Positives = 125/289 (43%), Gaps = 35/289 (12%)
Query: 31 VNKHKPWLE-PTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGE-ICGFKIHGQNVPFDA 88
VNK P + P Y V E+ + ++ P+++++ +P G+ I I G PF
Sbjct: 2179 VNKAMPVFDKPFYTASVNED---IRMNTPILSINATSP---EGQGIIYIIIDGD--PFKQ 2230
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+D TG V++ LD E+ Y TI+A D G + TV + VNDVN
Sbjct: 2231 FNIDFDTG--VLKVVSPLDYEVTSAYKLTIRASDALTGARA-------EVTVDLLVNDVN 2281
Query: 149 EYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEII-----TPDVPFT 202
+ P+F + +Y T+ E + +L+V ++DAD + +++ Y+I+ + D
Sbjct: 2282 DNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDAD--SENNKMVHYQIVQDTYNSTDYFHI 2339
Query: 203 VDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT--CTPGWQGWNN 260
G I L++ L V + D G + +VLV I I P + N
Sbjct: 2340 DSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVF----N 2395
Query: 261 RIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTY 309
++ YE LA P H TC + + + + I G DR ++
Sbjct: 2396 QLIYESYVSELA--PRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSF 2442
Score = 53.9 bits (128), Expect = 7e-07
Identities = 49/152 (32%), Positives = 65/152 (42%), Gaps = 8/152 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G I E LD EL K + ++A DG S ATV+I + DVN+ P F +
Sbjct: 3291 GGISVSEVLDYELCKRFYLVVEA------KDGGTPALSAVATVNINLTDVNDNPPKFSQD 3344
Query: 158 SYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GYIKNTEKL 215
Y A + E DS++ + A D D P S D FTVD G +K +KL
Sbjct: 3345 VYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKL 3404
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ + Y L V A D G + V I I
Sbjct: 3405 DRERVSGYSLLVQAVDSGIPAMSSTATVNIDI 3436
Score = 53.5 bits (127), Expect = 9e-07
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVK-KSHKATVHIQVNDVNEYAPVFKE 156
GVI +++ LD E Y IQA TN+ + ATV+IQ+ D N+ APVF
Sbjct: 1721 GVITTQKALDYERTSSYQLIIQA---------TNMAGMASNATVNIQIVDENDNAPVFLF 1771
Query: 157 KSYKATVIEGKQYDSILR--------VEAVDADCSPQFSQICSYEII--TPDVPFTVDKD 206
Y ++ E +SI+R + A DAD + + + Y+I+ T FTVD
Sbjct: 1772 SQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNR--NALLVYQIVESTAKKFFTVDSS 1829
Query: 207 -GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
G I+ L++ + V D G + T + V+++I+ T
Sbjct: 1830 TGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVT 1874
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/155 (31%), Positives = 81/155 (52%), Gaps = 15/155 (9%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVI + + LD E Y T+ A D G P + ++ V+I+V DVN+ AP+ E
Sbjct: 1098 GVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE------VYIEVEDVNDNAPLTSEP 1151
Query: 158 SYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIIT--PDVPFTVD-KDGYIKNT- 212
Y V+E D S+++++A D D S ++ +Y I + P F ++ K G I T
Sbjct: 1152 IYYPVVMENSPKDVSVIQIQAEDPDSSS--NEKLTYRITSGNPQNFFAINIKTGLITTTS 1209
Query: 213 EKLNYGKEHQYKLTVTAYDCG--KKRATEDVLVKI 245
KL+ ++ ++ L VT D G K++T V+V++
Sbjct: 1210 RKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQV 1244
Score = 50.8 bits (120), Expect = 6e-06
Identities = 64/232 (27%), Positives = 100/232 (43%), Gaps = 24/232 (10%)
Query: 31 VNKHKPWL-EPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN + P EP Y+ +V EN D +I + + P + E ++I N P +
Sbjct: 1141 VNDNAPLTSEPIYYPVVMENSPK---DVSVIQIQAEDPDSSSNEKLTYRITSGN-PQNFF 1196
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
++ TG + + KLD E Q ++ + D G P K V +QV D N+
Sbjct: 1197 AINIKTGL-ITTTSRKLDREQQAEHFLEVTVTDGGPSP------KQSTIWVVVQVLDEND 1249
Query: 150 YAPVFKEKSYKATVIE---GKQYDSILRVEAVDADCSPQFSQICSYEII--TPDVPFTVD 204
P F EK Y+ + E K+ + I R A D D P SY I+ D F +D
Sbjct: 1250 NKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAE--ISYSIVDGNDDGKFFID 1307
Query: 205 -KDGYIKNTEKLNYGKEHQYKLTVTAYDCGK--KRATEDVLVKISIKPTCTP 253
K G + + ++ G LT+ A D G+ K +T + ++ KP +P
Sbjct: 1308 PKTGMVSSRKQFTAGSYD--ILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP 1357
Score = 50.1 bits (118), Expect = 1e-05
Identities = 41/147 (27%), Positives = 74/147 (50%), Gaps = 15/147 (10%)
Query: 94 STGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPV 153
++ G++ ++LD E + +YS I+A D K G + T+ + ++DVN+ +P
Sbjct: 880 NSSTGIVYVADQLDRESKANYSLKIEARD--KAESGQQLFSV--VTLKVFLDDVNDCSPA 935
Query: 154 FKEKSYKATVIEGKQYDSILR-VEAVDADCS----PQFSQICSYEIITPDVPFTVDK-DG 207
F SY V+E +++ +E D D ++S + Y + F +DK G
Sbjct: 936 FIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDY-----NGRFEIDKASG 990
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGK 234
I+ +++L+Y K+ Y LTV A D G+
Sbjct: 991 AIRLSKELDYEKQQFYNLTVRAKDKGR 1017
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 14/203 (6%)
Query: 31 VNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
+N+ P+ + ++ V ++ + L DA F G++ F I N
Sbjct: 718 INRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVL-FTISDGNTD-SCFN 775
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D TG+ ++ +D E Y I YD G N +KS + I V D N+
Sbjct: 776 IDMETGQ--LKVLMPMDREHTDLYLLNITIYDLG------NPQKSSWRLLTINVEDANDN 827
Query: 151 APVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GY 208
+PVF + SY ++E + I++VEA D D +Y ++T F ++ G
Sbjct: 828 SPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGE--VTYSVLTDTQQFAINSSTGI 885
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
+ ++L+ + Y L + A D
Sbjct: 886 VYVADQLDRESKANYSLKIEARD 908
Score = 44.7 bits (104), Expect = 4e-04
Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 23/216 (10%)
Query: 39 EPTYHGIVTENDNTVLLDPPLI---ALDKDAPLRFAGEICGFKIHGQ--NVPFDAVVVDK 93
+P Y ++E+ VL D ++ A D+D + + + +H ++ +D
Sbjct: 1462 QPNYDVTISED---VLPDTEILQIEATDRDEKHKLS-----YTVHSSIDSISMRKFRIDP 1513
Query: 94 STGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPV 153
STG V+ + E+LD E Q + I D + P N+ A V + V D N+++P
Sbjct: 1514 STG--VLYTAERLDHEAQDKHILNIMVRD-QEFPYRRNL-----ARVIVNVEDANDHSPY 1565
Query: 154 FKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GYIKN 211
F Y+A+V E S +L+V A+D D I + E F ++ G I
Sbjct: 1566 FTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITI 1625
Query: 212 TEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
++ + Q+ L++ D G + +V+IS+
Sbjct: 1626 CKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISV 1661
Score = 44.3 bits (103), Expect = 6e-04
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPD 198
V+IQV D+N+ P+F +Y T+ E S+ +V A DAD + Y D
Sbjct: 144 VNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSN-GEFYYYFKNKVD 202
Query: 199 VPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKK 235
+ G I + +LNY ++++Y L + A D G K
Sbjct: 203 LFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMK 239
Score = 44.3 bits (103), Expect = 6e-04
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 31 VNKHKPWLEPT-YHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVP---F 86
+N +KP E + Y I+ E + A+D D G++ + +H + P
Sbjct: 2807 LNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGAN--GQVT-YSLHSDSQPEKVM 2863
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
+A +D +TG I + + LD E ++F++ A D G+ S A V ++V D
Sbjct: 2864 EAFNIDSNTGW--ISTLKDLDHETDPTFTFSVVASDLGEA-----FSLSSTALVSVRVTD 2916
Query: 147 VNEYAPVFKEKSYKATVIEGKQYDSILRVEAV-DADCSPQFSQICSYEI 194
+N+ APVF ++ Y+ V E ++ V + D D S Q+ SY I
Sbjct: 2917 INDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQV-SYHI 2964
Score = 43.9 bits (102), Expect = 7e-04
Identities = 41/155 (26%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Query: 95 TGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVF 154
+ G+I ++ LD E Q Y+ +++A D G +++ TV I V D+N+ PVF
Sbjct: 3182 SSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSL-----TTVTITVLDINDNPPVF 3236
Query: 155 KEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNT 212
+ + Y TV E + +L V A D F ++ K G I +
Sbjct: 3237 ERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVS 3296
Query: 213 EKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
E L+Y ++ L V A D G + V I++
Sbjct: 3297 EVLDYELCKRFYLVVEAKDGGTPALSAVATVNINL 3331
Score = 42.7 bits (99), Expect = 0.002
Identities = 49/154 (31%), Positives = 70/154 (45%), Gaps = 21/154 (13%)
Query: 98 GVIRSKEKLDCELQK-DYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKE 156
G + KE + +L +Y TI A D GK S +V + + VN+ PVF +
Sbjct: 2137 GNVILKEAFNSDLSNIEYGVTILAKDGGK--------PSLSTSVELPITIVNKAMPVFDK 2188
Query: 157 KSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEII--TPDVPFTVDKD-GYIKNT 212
Y A+V E + ++ IL + A SP+ Q Y II P F +D D G +K
Sbjct: 2189 PFYTASVNEDIRMNTPILSINAT----SPE-GQGIIYIIIDGDPFKQFNIDFDTGVLKVV 2243
Query: 213 EKLNYGKEHQYKLTVTAYDC---GKKRATEDVLV 243
L+Y YKLT+ A D + T D+LV
Sbjct: 2244 SPLDYEVTSAYKLTIRASDALTGARAEVTVDLLV 2277
Score = 41.6 bits (96), Expect = 0.004
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Query: 130 TNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQ 188
TN + KA V I + D N++ P F++ Y A V E S+L V A D D +
Sbjct: 448 TNKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGE--NG 505
Query: 189 ICSYEIITPD-VPFTVDK-DGYIKNTEKLNYGKEHQ-YKLTVTAYDCGKK-RATEDVLVK 244
+Y I + + +PF +++ G I TE+L++ + Y+ V A D G R +V V
Sbjct: 506 YITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVT 565
Query: 245 ISI 247
I I
Sbjct: 566 IRI 568
Score = 41.6 bits (96), Expect = 0.004
Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 12/157 (7%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
VD STG IR+ LD E + F + D G + V+I+V DVN+
Sbjct: 1826 VDSSTG--AIRTIANLDHETIAHFHFHVHVRDSGS----PQLTAESPVEVNIEVTDVNDN 1879
Query: 151 APVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVP-FTVDKDGY 208
PVF + ++ ++ +L+V A D D + +Y ++ + F +D +
Sbjct: 1880 PPVFTQAVFETILLLPTYVGVEVLKVSATDPD--SEVPPELTYSLMEGSLDHFLIDSNSG 1937
Query: 209 IKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKI 245
+ + N K+H Y L V D GK +T V + +
Sbjct: 1938 VLTIKNNNLSKDH-YMLIVKVSD-GKFYSTSMVTIMV 1972
Score = 39.7 bits (91), Expect = 0.014
Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D +GE +++ LD E YS +A D G + ++ +H+ + DVN+
Sbjct: 3078 LDPESGE--LKTLALLDRERIPVYSLMAKATDGGG--------RFCQSNIHLILEDVNDN 3127
Query: 151 APVFKEKSYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGY 208
PVF Y V E ++L RV+AVD D + S V F++D G
Sbjct: 3128 PPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGV-FSIDSSSGI 3186
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I + L+ ++ Y ++V A D
Sbjct: 3187 IILEQPLDREQQSSYNISVRATD 3209
Score = 39.3 bits (90), Expect = 0.018
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIIT 196
A VHI+V N Y+P F + +Y A V E + ++ V A D D + QI SY II
Sbjct: 2480 AQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGD-PGTYGQI-SYAIIN 2537
Query: 197 PDVP--FTVDKDGYIKNTEKLN 216
F +D +G + TE+L+
Sbjct: 2538 DFAKDRFLIDSNGQVITTERLD 2559
Score = 38.9 bits (89), Expect = 0.024
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 17/153 (11%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V+++ TG I+ ++LD E + F + A V V I+V D+N+
Sbjct: 2757 VIEQETG--TIKLDKRLDRETSPAFHFKVAATI-----PLDKVDIVFTVDVDIKVLDLND 2809
Query: 150 YAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVP------FT 202
PVF+ SY ++EG + + +V A+D D Q+ +Y + + P F
Sbjct: 2810 NKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGAN-GQV-TYSLHSDSQPEKVMEAFN 2867
Query: 203 VDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGK 234
+D + G+I + L++ + + +V A D G+
Sbjct: 2868 IDSNTGWISTLKDLDHETDPTFTFSVVASDLGE 2900
Score = 37.0 bits (84), Expect = 0.090
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 19/168 (11%)
Query: 93 KSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAP 152
KST + + D E Q+ Y ++A + D V + V + + D+N+ +P
Sbjct: 2029 KSTSGVIQTTGVPFDREEQELYELVVEA---SRELDHLRVAR---VVVRVNIEDINDNSP 2082
Query: 153 VFKEKSYKATV-IEGKQYDSILRVEAVDADCSPQ------FSQICSYEIITPDVPFTVDK 205
VF Y A V ++ + I +V A+D D P + I P+ + K
Sbjct: 2083 VFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNVILK 2142
Query: 206 DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTP 253
+ + + + YG +T+ A D GK + V + I+I P
Sbjct: 2143 EAFNSDLSNIEYG------VTILAKDGGKPSLSTSVELPITIVNKAMP 2184
Score = 35.0 bits (79), Expect = 0.34
Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 13/145 (8%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVI +L+ + + Y I A D G G N S A +++ + +NE+AP
Sbjct: 211 GVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSS-TAKLYVHIERINEHAPTIHVV 269
Query: 158 SYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDV--PFTVDKDGYIKNTEKL 215
++ +E + +++ V+ +D + +I S I+ D F + K+G N K+
Sbjct: 270 THVPFSLEKEPTYAVVTVDDLDDGAN---GEIESVSIVAGDPLDQFFLAKEGKWLNEYKI 326
Query: 216 NYGKE-------HQYKLTVTAYDCG 233
K+ + Y LT+ A D G
Sbjct: 327 KERKQIDWESFPYGYNLTLQAKDKG 351
Score = 35.0 bits (79), Expect = 0.34
Identities = 55/213 (25%), Positives = 96/213 (45%), Gaps = 34/213 (15%)
Query: 32 NKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNV-PFDAV 89
N H P + +P Y V E+ + A DKD + + I N+ PF
Sbjct: 466 NDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKD---KGENGYITYSIASLNLLPF--- 519
Query: 90 VVDKSTGEGVIRSKEKLDCELQKD-YSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
V+++ TG VI + E+LD E + Y F ++A D G + + + V I++ +VN
Sbjct: 520 VINQFTG--VISTTEELDFESSPEIYRFIVRASDWG-----SPYRHESEVNVTIRIGNVN 572
Query: 149 EYAPVFKEKSYKATVIEGKQYD-----SILRVEAVDADCSPQFSQICSYEIITPDVP--F 201
+ +P+F++ + + + YD I V A+D D ++ Y+II+ + F
Sbjct: 573 DNSPLFEKVACQGVI----SYDFPVGGHITAVSAIDID----ELELVKYKIISGNELGFF 624
Query: 202 TVDKDGYIKNTEK--LNYG-KEHQYKLTVTAYD 231
++ D + +K N G K + L +TA D
Sbjct: 625 YLNPDSGVLQLKKSLTNSGIKNGNFALRITATD 657
Score = 35.0 bits (79), Expect = 0.34
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 14/153 (9%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
+N + P + + Y G V E+D + L D+D + I G N P
Sbjct: 2917 INDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTS--DVNRQVSYHITGGN-PRGRF 2973
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ E + K LD E Q Y I A DG V + A V + V+DVN+
Sbjct: 2974 ALGLVQSEWKVYVKRPLDREEQDIYFLNITA------TDGLFVTQ---AMVEVSVSDVND 3024
Query: 150 YAPVFKEKSYKATVIEGKQYDS-ILRVEAVDAD 181
+PV + +Y A + E + IL+V A DAD
Sbjct: 3025 NSPVCDQVAYTALLPEDIPSNKIILKVSAKDAD 3057
Score = 31.6 bits (70), Expect = 3.8
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCE--LQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQV 144
D ++D + G + + E+LD E L+ D S ++A D G ++ TV + V
Sbjct: 2542 DRFLIDSN---GQVITTERLDRENPLEGDVSIFVRALDGGG--------RTTFCTVRVIV 2590
Query: 145 NDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
D N+ AP F Y+A+V + + + +V+A+D D
Sbjct: 2591 VDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPD 2628
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 64.3 bits (155), Expect = 5e-10
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 41/259 (15%)
Query: 11 PAARLLLAGLLCGGGVWAAR---------VNKHKPWLEPTYHGIVTENDNTVLLDPPL-- 59
P +LL+ L GG+ AR VN + P ++ Y IV ++TV+L +
Sbjct: 321 PNHKLLV--LASDGGLMPARAMVLVNVTDVNDNVPSIDIRY--IVNPVNDTVVLSENIPL 376
Query: 60 ---IAL----DKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQK 112
IAL DKDA G + F H +PF V + + ++ + LD E K
Sbjct: 377 NTKIALITVTDKDADHN--GRVTCFTDH--EIPFRLRPV--FSNQFLLETAAYLDYESTK 430
Query: 113 DYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD-S 171
+Y+ + A D GK P + A + I+V D N+ APVF + ++ E
Sbjct: 431 EYAIKLLAADAGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 172 ILRVEAVDADCSPQFSQICSYEIITPDVP--FTVD-KDGYIKNTEKLNYGKEHQYKLTVT 228
+ +V A+DAD P +Y ++ PD P F++D + G + +KL+ KE +Y T+
Sbjct: 485 LTKVSAMDADSGPNAK--INY-LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 229 AYDCGKKRATEDVLVKISI 247
A D G T +V V +SI
Sbjct: 542 AKDNGVPPLTSNVTVFVSI 560
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ +KLD E + Y FTI A D G P +NV TV + + D N+ +PVF
Sbjct: 520 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV------TVFVSIIDQNDNSPVFTHN 573
Query: 158 SYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNTEKL 215
Y V E ++ ++ + D D + + I+ + FT+D + G I+
Sbjct: 574 EYNFYVPENLPRHGTVGLITVTDPDYGD--NSAVTLSILDENDDFTIDSQTGVIRPNISF 631
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ K+ Y V A D G+ + V I++
Sbjct: 632 DREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D +D TG VIR D E Q+ Y+F ++A D G+ V +S A V I V D
Sbjct: 614 DDFTIDSQTG--VIRPNISFDREKQESYTFYVKAEDGGR------VSRSSSAKVTINVVD 665
Query: 147 VNEYAPVF----KEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEII---TPDV 199
VN+ PVF SY+ + + +V AVD D + Y I+ T D+
Sbjct: 666 VNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTG--MNAEVRYSIVGGNTRDL 723
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLV 243
F +D++ G I EK + +++ V A D G+ + V++
Sbjct: 724 -FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 79 IHGQNVPFDAVVVDKSTGEGV--IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
I QN+ F V++ G+ + + +++LD E + Y + K DG ++S
Sbjct: 179 IKSQNI-FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV------KVEDGGFPQRSS 231
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEII 195
A + + V D N+ PVFKE + ++ E S+ ++ A DAD S+ +
Sbjct: 232 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 291
Query: 196 TPDVPFTV----DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKIS 246
++ + G I E L+ + +KL V A D G A VLV ++
Sbjct: 292 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT 346
Score = 32.0 bits (71), Expect = 2.9
Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I KE LD E ++ + A D G P +A V + V DVN+ P +
Sbjct: 307 GLITIKEPLDREETPNHKLLVLASDGGLMPA--------RAMVLVNVTDVNDNVPSIDIR 358
Query: 158 ----SYKATVIEGKQYD-----SILRVEAVDADCSPQFSQICSYEIITPDVPFTV----D 204
TV+ + +++ V DAD + + + +EI PF +
Sbjct: 359 YIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEI-----PFRLRPVFS 413
Query: 205 KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
++ L+Y +Y + + A D GK + ++ I +K
Sbjct: 414 NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVK 457
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 64.3 bits (155), Expect = 5e-10
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 41/259 (15%)
Query: 11 PAARLLLAGLLCGGGVWAAR---------VNKHKPWLEPTYHGIVTENDNTVLLDPPL-- 59
P +LL+ L GG+ AR VN + P ++ Y IV ++TV+L +
Sbjct: 321 PNHKLLV--LASDGGLMPARAMVLVNVTDVNDNVPSIDIRY--IVNPVNDTVVLSENIPL 376
Query: 60 ---IAL----DKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQK 112
IAL DKDA G + F H +PF V + + ++ + LD E K
Sbjct: 377 NTKIALITVTDKDADHN--GRVTCFTDH--EIPFRLRPV--FSNQFLLETAAYLDYESTK 430
Query: 113 DYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD-S 171
+Y+ + A D GK P + A + I+V D N+ APVF + ++ E
Sbjct: 431 EYAIKLLAADAGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 172 ILRVEAVDADCSPQFSQICSYEIITPDVP--FTVD-KDGYIKNTEKLNYGKEHQYKLTVT 228
+ +V A+DAD P +Y ++ PD P F++D + G + +KL+ KE +Y T+
Sbjct: 485 LTKVSAMDADSGPNAK--INY-LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 229 AYDCGKKRATEDVLVKISI 247
A D G T +V V +SI
Sbjct: 542 AKDNGVPPLTSNVTVFVSI 560
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ +KLD E + Y FTI A D G P +NV TV + + D N+ +PVF
Sbjct: 520 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV------TVFVSIIDQNDNSPVFTHN 573
Query: 158 SYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNTEKL 215
Y V E ++ ++ + D D + + I+ + FT+D + G I+
Sbjct: 574 EYNFYVPENLPRHGTVGLITVTDPDYGD--NSAVTLSILDENDDFTIDSQTGVIRPNISF 631
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ K+ Y V A D G+ + V I++
Sbjct: 632 DREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D +D TG VIR D E Q+ Y+F ++A D G+ V +S A V I V D
Sbjct: 614 DDFTIDSQTG--VIRPNISFDREKQESYTFYVKAEDGGR------VSRSSSAKVTINVVD 665
Query: 147 VNEYAPVF----KEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEII---TPDV 199
VN+ PVF SY+ + + +V AVD D + Y I+ T D+
Sbjct: 666 VNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTG--MNAEVRYSIVGGNTRDL 723
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLV 243
F +D++ G I EK + +++ V A D G+ + V++
Sbjct: 724 -FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 79 IHGQNVPFDAVVVDKSTGEGV--IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
I QN+ F V++ G+ + + +++LD E + Y + K DG ++S
Sbjct: 179 IKSQNI-FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV------KVEDGGFPQRSS 231
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEII 195
A + + V D N+ PVFKE + ++ E S+ ++ A DAD S+ +
Sbjct: 232 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 291
Query: 196 TPDVPFTV----DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKIS 246
++ + G I E L+ + +KL V A D G A VLV ++
Sbjct: 292 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT 346
Score = 32.0 bits (71), Expect = 2.9
Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I KE LD E ++ + A D G P +A V + V DVN+ P +
Sbjct: 307 GLITIKEPLDREETPNHKLLVLASDGGLMPA--------RAMVLVNVTDVNDNVPSIDIR 358
Query: 158 ----SYKATVIEGKQYD-----SILRVEAVDADCSPQFSQICSYEIITPDVPFTV----D 204
TV+ + +++ V DAD + + + +EI PF +
Sbjct: 359 YIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEI-----PFRLRPVFS 413
Query: 205 KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
++ L+Y +Y + + A D GK + ++ I +K
Sbjct: 414 NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVK 457
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 64.3 bits (155), Expect = 5e-10
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 41/259 (15%)
Query: 11 PAARLLLAGLLCGGGVWAAR---------VNKHKPWLEPTYHGIVTENDNTVLLDPPL-- 59
P +LL+ L GG+ AR VN + P ++ Y IV ++TV+L +
Sbjct: 321 PNHKLLV--LASDGGLMPARAMVLVNVTDVNDNVPSIDIRY--IVNPVNDTVVLSENIPL 376
Query: 60 ---IAL----DKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQK 112
IAL DKDA G + F H +PF V + + ++ + LD E K
Sbjct: 377 NTKIALITVTDKDADHN--GRVTCFTDH--EIPFRLRPV--FSNQFLLETAAYLDYESTK 430
Query: 113 DYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD-S 171
+Y+ + A D GK P + A + I+V D N+ APVF + ++ E
Sbjct: 431 EYAIKLLAADAGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 172 ILRVEAVDADCSPQFSQICSYEIITPDVP--FTVD-KDGYIKNTEKLNYGKEHQYKLTVT 228
+ +V A+DAD P +Y ++ PD P F++D + G + +KL+ KE +Y T+
Sbjct: 485 LTKVSAMDADSGPNAK--INY-LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 229 AYDCGKKRATEDVLVKISI 247
A D G T +V V +SI
Sbjct: 542 AKDNGVPPLTSNVTVFVSI 560
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ +KLD E + Y FTI A D G P +NV TV + + D N+ +PVF
Sbjct: 520 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV------TVFVSIIDQNDNSPVFTHN 573
Query: 158 SYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNTEKL 215
Y V E ++ ++ + D D + + I+ + FT+D + G I+
Sbjct: 574 EYNFYVPENLPRHGTVGLITVTDPDYGD--NSAVTLSILDENDDFTIDSQTGVIRPNISF 631
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ K+ Y V A D G+ + V I++
Sbjct: 632 DREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D +D TG VIR D E Q+ Y+F ++A D G+ V +S A V I V D
Sbjct: 614 DDFTIDSQTG--VIRPNISFDREKQESYTFYVKAEDGGR------VSRSSSAKVTINVVD 665
Query: 147 VNEYAPVF----KEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEII---TPDV 199
VN+ PVF SY+ + + +V AVD D + Y I+ T D+
Sbjct: 666 VNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTG--MNAEVRYSIVGGNTRDL 723
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLV 243
F +D++ G I EK + +++ V A D G+ + V++
Sbjct: 724 -FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 79 IHGQNVPFDAVVVDKSTGEGV--IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
I QN+ F V++ G+ + + +++LD E + Y + K DG ++S
Sbjct: 179 IKSQNI-FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV------KVEDGGFPQRSS 231
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEII 195
A + + V D N+ PVFKE + ++ E S+ ++ A DAD S+ +
Sbjct: 232 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 291
Query: 196 TPDVPFTV----DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKIS 246
++ + G I E L+ + +KL V A D G A VLV ++
Sbjct: 292 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT 346
Score = 32.0 bits (71), Expect = 2.9
Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I KE LD E ++ + A D G P +A V + V DVN+ P +
Sbjct: 307 GLITIKEPLDREETPNHKLLVLASDGGLMPA--------RAMVLVNVTDVNDNVPSIDIR 358
Query: 158 ----SYKATVIEGKQYD-----SILRVEAVDADCSPQFSQICSYEIITPDVPFTV----D 204
TV+ + +++ V DAD + + + +EI PF +
Sbjct: 359 YIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEI-----PFRLRPVFS 413
Query: 205 KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
++ L+Y +Y + + A D GK + ++ I +K
Sbjct: 414 NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVK 457
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 64.3 bits (155), Expect = 5e-10
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 41/259 (15%)
Query: 11 PAARLLLAGLLCGGGVWAAR---------VNKHKPWLEPTYHGIVTENDNTVLLDPPL-- 59
P +LL+ L GG+ AR VN + P ++ Y IV ++TV+L +
Sbjct: 321 PNHKLLV--LASDGGLMPARAMVLVNVTDVNDNVPSIDIRY--IVNPVNDTVVLSENIPL 376
Query: 60 ---IAL----DKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQK 112
IAL DKDA G + F H +PF V + + ++ + LD E K
Sbjct: 377 NTKIALITVTDKDADHN--GRVTCFTDH--EIPFRLRPV--FSNQFLLETAAYLDYESTK 430
Query: 113 DYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD-S 171
+Y+ + A D GK P + A + I+V D N+ APVF + ++ E
Sbjct: 431 EYAIKLLAADAGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 172 ILRVEAVDADCSPQFSQICSYEIITPDVP--FTVD-KDGYIKNTEKLNYGKEHQYKLTVT 228
+ +V A+DAD P +Y ++ PD P F++D + G + +KL+ KE +Y T+
Sbjct: 485 LTKVSAMDADSGPNAK--INY-LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 229 AYDCGKKRATEDVLVKISI 247
A D G T +V V +SI
Sbjct: 542 AKDNGVPPLTSNVTVFVSI 560
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ +KLD E + Y FTI A D G P +NV TV + + D N+ +PVF
Sbjct: 520 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV------TVFVSIIDQNDNSPVFTHN 573
Query: 158 SYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNTEKL 215
Y V E ++ ++ + D D + + I+ + FT+D + G I+
Sbjct: 574 EYNFYVPENLPRHGTVGLITVTDPDYGD--NSAVTLSILDENDDFTIDSQTGVIRPNISF 631
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ K+ Y V A D G+ + V I++
Sbjct: 632 DREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D +D TG VIR D E Q+ Y+F ++A D G+ V +S A V I V D
Sbjct: 614 DDFTIDSQTG--VIRPNISFDREKQESYTFYVKAEDGGR------VSRSSSAKVTINVVD 665
Query: 147 VNEYAPVF----KEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEII---TPDV 199
VN+ PVF SY+ + + +V AVD D + Y I+ T D+
Sbjct: 666 VNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTG--MNAEVRYSIVGGNTRDL 723
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLV 243
F +D++ G I EK + +++ V A D G+ + V++
Sbjct: 724 -FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 79 IHGQNVPFDAVVVDKSTGEGV--IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
I QN+ F V++ G+ + + +++LD E + Y + K DG ++S
Sbjct: 179 IKSQNI-FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV------KVEDGGFPQRSS 231
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEII 195
A + + V D N+ PVFKE + ++ E S+ ++ A DAD S+ +
Sbjct: 232 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 291
Query: 196 TPDVPFTV----DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKIS 246
++ + G I E L+ + +KL V A D G A VLV ++
Sbjct: 292 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT 346
Score = 32.0 bits (71), Expect = 2.9
Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I KE LD E ++ + A D G P +A V + V DVN+ P +
Sbjct: 307 GLITIKEPLDREETPNHKLLVLASDGGLMPA--------RAMVLVNVTDVNDNVPSIDIR 358
Query: 158 ----SYKATVIEGKQYD-----SILRVEAVDADCSPQFSQICSYEIITPDVPFTV----D 204
TV+ + +++ V DAD + + + +EI PF +
Sbjct: 359 YIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEI-----PFRLRPVFS 413
Query: 205 KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
++ L+Y +Y + + A D GK + ++ I +K
Sbjct: 414 NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVK 457
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 63.2 bits (152), Expect = 1e-09
Identities = 43/159 (27%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D TGE I+ LD E +++Y+ I+A D G+ P N IQV D+N++
Sbjct: 595 IDSLTGE--IQVVAPLDFEAEREYALRIRAQDAGRPPLSNNT-----GLASIQVVDINDH 647
Query: 151 APVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDK-DGY 208
P+F ++ +V+E S++ ++AVDAD S + PD PF ++ G+
Sbjct: 648 IPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGW 707
Query: 209 IKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ + L+ Y V A D G + V +++
Sbjct: 708 VSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTV 746
Score = 58.9 bits (141), Expect = 2e-08
Identities = 64/220 (29%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 26 VWAARVNKHKPWLEPT-YHGIVTENDNTVLLDPPLIALDKDAP------LRFAGEICGFK 78
V A N H P E Y + EN L A D DAP RF G
Sbjct: 421 VTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARA 480
Query: 79 IHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
A + G+I + ++D E + Y ++A D G+ P +S
Sbjct: 481 AA-------AAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPG----PRSATV 529
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITP 197
VHI V D N+ AP F EK Y A V E + + +LRV A D D + + Y II+
Sbjct: 530 RVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRD--KDANGLVHYNIISG 587
Query: 198 DV--PFTVDK-DGYIKNTEKLNYGKEHQYKLTVTAYDCGK 234
+ F +D G I+ L++ E +Y L + A D G+
Sbjct: 588 NSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGR 627
Score = 53.1 bits (126), Expect = 1e-06
Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 18/204 (8%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN + P ++ Y G+V+E+ + A D+DA G + +G++ D
Sbjct: 954 VNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHAN--GRVQYTFQNGEDGDGDFT 1011
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ S G++R+ +LD E Y T A D G P T V ++ + V DVN+
Sbjct: 1012 IEPTS---GIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPV------SIQVMVQDVND 1062
Query: 150 YAPVFKEKSYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-- 206
APVF + ++ V E S++ ++ AVD D P + Y+I+ ++P D
Sbjct: 1063 NAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGP--NAHIMYQIVEGNIPELFQMDIF 1120
Query: 207 -GYIKNTEKLNYGKEHQYKLTVTA 229
G + L+Y +Y + V A
Sbjct: 1121 SGELTALIDLDYEARQEYVIVVQA 1144
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 9/154 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G I + LD E Q Y+ I A D G +K+ V + VNDVN+ AP F
Sbjct: 911 GAITLQAPLDYEDQVTYTLAITARDNGIP------QKADTTYVEVMVNDVNDNAPQFVAS 964
Query: 158 SYKATVIE-GKQYDSILRVEAVDADCSPQFS-QICSYEIITPDVPFTVD-KDGYIKNTEK 214
Y V E + S+L++ A D D Q D FT++ G ++ +
Sbjct: 965 HYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRR 1024
Query: 215 LNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
L+ Y+LT A D G V +++ ++
Sbjct: 1025 LDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQ 1058
Score = 44.7 bits (104), Expect = 4e-04
Identities = 49/220 (22%), Positives = 91/220 (41%), Gaps = 20/220 (9%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN ++P + YH + E+ + A+D+DA + +I G +
Sbjct: 749 VNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNR------F 802
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ G G++ LD + ++ + + A D H VHI + D N
Sbjct: 803 AISTQGGVGLVTLALPLDYKQERYFKLVLTASD--------RALHDH-CYVHINITDANT 853
Query: 150 YAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVP-FTVDKD-G 207
+ PVF+ Y +V E + S + V + D + ++I ++ ++P F +D D G
Sbjct: 854 HRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARIT--YLLEDNLPQFRIDADSG 911
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
I L+Y + Y L +TA D G + + V++ +
Sbjct: 912 AITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMV 951
Score = 43.5 bits (101), Expect = 0.001
Identities = 47/164 (28%), Positives = 67/164 (40%), Gaps = 20/164 (12%)
Query: 80 HGQNV----------PFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDG 129
HG+N P V++ +TG + LD E + Y F ++A D G P
Sbjct: 680 HGENARLEYSLTGVAPDTPFVINSATGW--VSVSGPLDRESVEHYFFGVEARDHGSPP-- 735
Query: 130 TNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFS- 187
S A+V + V DVN+ P F K Y + E S++ V AVD D + S
Sbjct: 736 ----LSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISY 791
Query: 188 QICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYD 231
QI T G + L+Y +E +KL +TA D
Sbjct: 792 QITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASD 835
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 62.0 bits (149), Expect = 3e-09
Identities = 56/222 (25%), Positives = 99/222 (44%), Gaps = 16/222 (7%)
Query: 31 VNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
VN H P T + +N + + D F G++ + + G N +
Sbjct: 709 VNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLV-YAVSGGNED-SCFM 766
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D TG +++ LD E Y+ I YD G +K+ +H+ V D N+
Sbjct: 767 IDMETG--MLKILSPLDRETTDKYTLNITVYDLGIP------QKAAWRLLHVVVVDANDN 818
Query: 151 APVFKEKSYKATVIEGKQ-YDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDK-DGY 208
P F ++SY V E K+ + I++VEA D D P + +Y I+T F++D G
Sbjct: 819 PPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGP--NGHVTYSIVTDTDTFSIDSVTGV 876
Query: 209 IKNTEKLNYGKEHQYKLTVTAYDCGKK--RATEDVLVKISIK 248
+ L+ +H++ L + A D ++ + V+VK+S++
Sbjct: 877 VNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLE 918
Score = 60.5 bits (145), Expect = 8e-09
Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 11/154 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I+ ++ LD ELQ Y+ +++A D G + + TV + V D+N+ PVF+ +
Sbjct: 3179 GIIQLEKPLDRELQAVYTLSLKAVD-----QGLPRRLTATGTVIVSVLDINDNPPVFEYR 3233
Query: 158 SYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDV--PFTVD-KDGYIKNTE 213
Y ATV E + +L+V A D + + +Y II+ + F++D K G + E
Sbjct: 3234 EYGATVSEDILVGTEVLQVYAASRDI--EANAEITYSIISGNEHGKFSIDSKTGAVFIIE 3291
Query: 214 KLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
L+Y H+Y LTV A D G ++ V +++
Sbjct: 3292 NLDYESSHEYYLTVEATDGGTPSLSDVATVNVNV 3325
Score = 59.3 bits (142), Expect = 2e-08
Identities = 65/224 (29%), Positives = 91/224 (40%), Gaps = 23/224 (10%)
Query: 31 VNKHKPWLEPTYHGIVTEND---NTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFD 87
+N + P E +G D T +L + D +A I HG+
Sbjct: 3223 INDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGK----- 3277
Query: 88 AVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDV 147
+D TG I E LD E +Y T++A DG S ATV++ V D+
Sbjct: 3278 -FSIDSKTGAVFII--ENLDYESSHEYYLTVEA------TDGGTPSLSDVATVNVNVTDI 3328
Query: 148 NEYAPVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEII--TPDVPFTVD 204
N+ PVF + +Y + E + S++ V A DAD P S I Y II FT+D
Sbjct: 3329 NDNTPVFSQDTYTTVISEDAVLEQSVITVMADDAD-GPSNSHI-HYSIIDGNQGSSFTID 3386
Query: 205 K-DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
G +K T+ L+ Y LTV A D G V I +
Sbjct: 3387 PVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDV 3430
Score = 56.6 bits (135), Expect = 1e-07
Identities = 56/221 (25%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 32 NKHKPWLEPTYHGIVTENDN---TVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDA 88
N H+P + + +V D T +L + A+D+D + + + P
Sbjct: 1450 NDHRPQFSTSKYEVVIPEDTAPETEILQ--ISAVDQDEKNKLI-----YTLQSSRDPLSL 1502
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
G + + EKLD E ++ T+ D VK++ A + + V+D N
Sbjct: 1503 KKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRD-----QDVPVKRNF-ARIVVNVSDTN 1556
Query: 149 EYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD- 206
++AP F SYK V E S +L+V A+D D + S E F +D
Sbjct: 1557 DHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVL 1616
Query: 207 GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
G IK ++L+ + +Y L V A D G +E V+I +
Sbjct: 1617 GSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFV 1657
Score = 55.8 bits (133), Expect = 2e-07
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 17/169 (10%)
Query: 85 PFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQV 144
PF ++ +TG VI LD E Y +I+A D G + V I V
Sbjct: 2223 PFSQFTINFNTG--VINVIAPLDFEAHPAYKLSIRATDSLTGAHA-------EVFVDIIV 2273
Query: 145 NDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEII----TPDV 199
+D+N+ PVF ++SY T+ E S+++V A D+D P ++ SY++
Sbjct: 2274 DDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEP--NRGISYQMFGNHSKSHD 2331
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
F VD G I L+Y + Q+ + V A D G + DV+V + +
Sbjct: 2332 HFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDV 2380
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 16/156 (10%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G ++ + LD E Y+ T+QA D G P + + TV+I V+DVN+ APVF
Sbjct: 3390 GEVKVTKLLDRETISGYTLTVQASDNGSPP------RVNTTTVNIDVSDVNDNAPVFSRG 3443
Query: 158 SYKATVIEGKQYD-SILRVEAVDADCS---PQFSQICSYEIIT--PDVPFTVDKDGYIKN 211
+Y + E K S+L++ D D S P F + I+T + F V+ G +
Sbjct: 3444 NYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPF----FFTIVTGNDEKAFEVNPQGVLLT 3499
Query: 212 TEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ + ++ Y L V D GK + + + I +
Sbjct: 3500 SSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 53.9 bits (128), Expect = 7e-07
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 11/153 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVI + ++LD E Y T+ A D G P + ++ ++I+V DVN+ AP E
Sbjct: 1089 GVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIE------IYIEVEDVNDNAPQTSEP 1142
Query: 158 SYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVPFTV-DKDGYIKNT-EK 214
Y ++E D S++++EA D D S + P F++ K G I T K
Sbjct: 1143 VYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRK 1202
Query: 215 LNYGKEHQYKLTVTAYDCGK--KRATEDVLVKI 245
L+ ++ ++ L VT D G K V+VKI
Sbjct: 1203 LDREQQDEHILEVTVTDNGSPPKSTIARVIVKI 1235
Score = 53.5 bits (127), Expect = 9e-07
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 18/157 (11%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
++ V+D+ +G ++ ++ LD E K Y F+I A C + D + S V IQV D
Sbjct: 2749 ESFVIDRQSGR--LKLEKSLDHETTKWYQFSILAR-CTQ--DDHEMVAS--VDVSIQVKD 2801
Query: 147 VNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSP------QFSQICSYEIITPDV 199
N+ +PVF+ Y+A ++E S ++++ A DAD Q S E+I
Sbjct: 2802 ANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIE--- 2858
Query: 200 PFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCGKK 235
F ++ + G+I ++L++ K Y++ V A D G+K
Sbjct: 2859 SFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEK 2895
Score = 50.8 bits (120), Expect = 6e-06
Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 18/167 (10%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D +D TG V+ LD ELQ ++S I+A D + + V + + D
Sbjct: 866 DTFSIDSVTG--VVNIARPLDRELQHEHSLKIEARDQAR----EEPQLFSTVVVKVSLED 919
Query: 147 VNEYAPVFKEKSYKATVIEGKQYDSILR-VEAVDADCSPQFSQICSYEIITPDVPFTVDK 205
VN+ P F +Y+ V E +++ +EA D D Q Q+ + + F VDK
Sbjct: 920 VNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLG-QSGQVRYSLLDHGEGNFDVDK 978
Query: 206 -DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTC 251
G ++ ++L++ K+ Y LTV A D GK +S+ TC
Sbjct: 979 LSGAVRIVQQLDFEKKQVYNLTVRAKDKGK---------PVSLSSTC 1016
Score = 50.4 bits (119), Expect = 8e-06
Identities = 65/239 (27%), Positives = 103/239 (43%), Gaps = 54/239 (22%)
Query: 31 VNKHKPWLEPT------YHGIVTEND------NTVLLDPPLIALDKDAPLRFAGEICGFK 78
++K KP LEP + V E+D + ++PP I L F
Sbjct: 1346 ISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPL-------------WFD 1392
Query: 79 IHGQNVP--FDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
I G N FD VDK TG ++ + LD E + +Y+ T++A DGT +
Sbjct: 1393 ITGGNYDSHFD---VDKGTGTIIVA--KPLDAEQKSNYNLTVEA------TDGTTTILTQ 1441
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEII 195
V I+V D N++ P F Y+ + E ++ IL++ AVD D + Y +
Sbjct: 1442 ---VFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKL----IYTLQ 1494
Query: 196 TPDVPFTVDK------DGYIKNTEKLNYGKEHQYKLTVTA--YDCGKKRATEDVLVKIS 246
+ P ++ K G + +EKL++ HQ+ LTV D KR ++V +S
Sbjct: 1495 SSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVS 1553
Score = 50.4 bits (119), Expect = 8e-06
Identities = 65/227 (28%), Positives = 108/227 (47%), Gaps = 36/227 (15%)
Query: 37 WLEPTYHGIVTEND--NTVLL---DPPLIA----LDKDAPLRFAGEICGFKIHGQNVPFD 87
+++ Y G+++E+ N+V+L + PL+ DKD+ I +H
Sbjct: 1765 FMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTY----- 1819
Query: 88 AVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDV 147
+D STG I + LD E + FT+Q +D G + + A V + V D+
Sbjct: 1820 -FAIDSSTG--AIHTVLSLDYEETSIFHFTVQVHDMGT----PRLFAEYAANVTVHVIDI 1872
Query: 148 NEYAPVFKEKSYKAT-VIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDV--PFTVD 204
N+ PVF + Y+A+ ++ + ++ V A DAD S FSQ+ Y I ++ F++D
Sbjct: 1873 NDCPPVFAKPLYEASLLLPTYKGVKVITVNATDAD-SSAFSQLI-YSITEGNIGEKFSMD 1930
Query: 205 -KDG--YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
K G ++NT +L +Y+LTV A D R VKI++K
Sbjct: 1931 YKTGALTVQNTTQL----RSRYELTVRASD---GRFAGLTSVKINVK 1970
Score = 47.0 bits (110), Expect = 9e-05
Identities = 44/154 (28%), Positives = 76/154 (49%), Gaps = 16/154 (10%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G +++ LD E Q Y ++A D G + +A++ + + DVN+ AP F
Sbjct: 3077 GELKTSTPLDREEQAVYHLLVRATDGGG--------RFCQASIVLTLEDVNDNAPEFSAD 3128
Query: 158 SYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEII-TPDVPFTVDK-DGYIKNTEK 214
Y TV E + ++L RV+A DAD ++ Y +I + D F++++ G I+ +
Sbjct: 3129 PYAITVFENTEPGTLLTRVQATDADAG--LNRKILYSLIDSADGQFSINELSGIIQLEKP 3186
Query: 215 LNYGKEHQYKLTVTAYDCGKKR---ATEDVLVKI 245
L+ + Y L++ A D G R AT V+V +
Sbjct: 3187 LDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSV 3220
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 12/140 (8%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G I + ++LD E + +Y + A D G+ ++ S A V + V DVN+ P F +
Sbjct: 2867 GWITTLKELDHEKRDNYQIKVVASDHGE-----KIQLSSTAIVDVTVTDVNDSPPRFTAE 2921
Query: 158 SYKATVIEGKQYDSILRV-EAVDADCSPQFSQICSYEIITPD-----VPFTVDKDGYIKN 211
YK TV E ++ + DAD S + ++ +Y I D T+ + +
Sbjct: 2922 IYKGTVSEDDPQGGVIAILSTTDAD-SEEINRQVTYFITGGDPLGQFAVETIQNEWKVYV 2980
Query: 212 TEKLNYGKEHQYKLTVTAYD 231
+ L+ K Y LT+TA D
Sbjct: 2981 KKPLDREKRDNYLLTITATD 3000
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 9/131 (6%)
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE 165
L+ E++ Y+ ++A + TNV+ K V +QV D N+ P+F SY ++ E
Sbjct: 108 LNREVKDHYTLIVKALE-----KNTNVEARTK--VRVQVLDTNDLRPLFSPTSYSVSLPE 160
Query: 166 GKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYK 224
SI RV A DAD S++ T D+ G I T +L+Y + Y+
Sbjct: 161 NTAIRTSIARVSATDADIGTNGEFYYSFKDRT-DMFAIHPTSGVIVLTGRLDYLETKLYE 219
Query: 225 LTVTAYDCGKK 235
+ + A D G K
Sbjct: 220 MEILAADRGMK 230
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 33/256 (12%)
Query: 42 YHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIR 101
Y G V+E+D + L D D+ ++ F G P V+ E +
Sbjct: 2923 YKGTVSEDDPQGGVIAILSTTDADSE-EINRQVTYFITGGD--PLGQFAVETIQNEWKVY 2979
Query: 102 SKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKA 161
K+ LD E + +Y TI A DGT S KA V ++V D N+ +PV ++ Y
Sbjct: 2980 VKKPLDREKRDNYLLTITA------TDGTF---SSKAIVEVKVLDANDNSPVCEKTLYSD 3030
Query: 162 T----VIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GYIKNTEKLN 216
T V+ GK I+++ A DAD ++I + + F ++ D G +K + L+
Sbjct: 3031 TIPEDVLPGK---LIMQISATDADIRSN-AEITYTLLGSGAEKFKLNPDTGELKTSTPLD 3086
Query: 217 YGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPN 276
++ Y L V A D G + +++ + +N E+ A+ VF N
Sbjct: 3087 REEQAVYHLLVRATDGGGRFCQASIVLTLE---------DVNDNAPEFSADPYAITVFEN 3137
Query: 277 IHLETCDEPVASVQAT 292
T + VQAT
Sbjct: 3138 TEPGTL---LTRVQAT 3150
Score = 38.1 bits (87), Expect = 0.040
Identities = 52/224 (23%), Positives = 91/224 (40%), Gaps = 21/224 (9%)
Query: 31 VNKHKPWL-EPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN + P EP Y+ + EN + + A D D+ + + +KI N P
Sbjct: 1132 VNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSS---SNDKLMYKITSGN-PQGFF 1187
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ TG + + KLD E Q ++ + D G P KS A V +++ D N+
Sbjct: 1188 SIHPKTGL-ITTTSRKLDREQQDEHILEVTVTDNGSPP------KSTIARVIVKILDEND 1240
Query: 150 YAPVFKEKSYKATVIEGKQYD--------SILRVEAVDADCSPQFSQICSYEIITPDVPF 201
P F +K YK + E ++ D + V A D D P S E F
Sbjct: 1241 NKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKF 1300
Query: 202 TVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKI 245
++ + ++++ + E+ L++ A D G+ + + + I
Sbjct: 1301 FIEPKTGVVSSKRFSAAGEYDI-LSIKAVDNGRPQKSSTTRLHI 1343
Score = 37.7 bits (86), Expect = 0.053
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 9/94 (9%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
VD STG +I LD E + ++ ++A D G ++V V + V D+N+
Sbjct: 2335 VDSSTG--LISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDV------IVTVDVTDLNDN 2386
Query: 151 APVFKEKSYKATVIEGKQYDSILR-VEAVDADCS 183
P+F+++ Y+A + E + + V+A DAD S
Sbjct: 2387 PPLFEQQIYEARISEHAPHGHFVTCVKAYDADSS 2420
Score = 37.0 bits (84), Expect = 0.090
Identities = 37/138 (26%), Positives = 62/138 (44%), Gaps = 14/138 (10%)
Query: 96 GEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFK 155
GE ++ + +LD L K+Y T+ A D G + A V + + +N+ PVF+
Sbjct: 2133 GEISLKKQFELDT-LNKEYLVTVVAKDGGN--------PAFSAEVIVPITVMNKAMPVFE 2183
Query: 156 EKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNTE 213
+ Y A + E Q S ++ V+A + F I + P FT++ G I
Sbjct: 2184 KPFYSAEIAESIQVHSPVVHVQANSPEGLKVFYSITDGD---PFSQFTINFNTGVINVIA 2240
Query: 214 KLNYGKEHQYKLTVTAYD 231
L++ YKL++ A D
Sbjct: 2241 PLDFEAHPAYKLSIRATD 2258
Score = 32.0 bits (71), Expect = 2.9
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 14/142 (9%)
Query: 109 ELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQ 168
+L+ Y T++A D G+ T+VK I V + E F + Y A V E
Sbjct: 1943 QLRSRYELTVRASD-GRFAGLTSVK--------INVKESKESHLKFTQDVYSAVVKENST 1993
Query: 169 YDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQ--YKLT 226
L V + A +P ++ Y I+ PD F + + + +T + +E Q + +
Sbjct: 1994 EAETLAV--ITAIGNP-INEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVV 2050
Query: 227 VTAYDCGKKRATEDVLVKISIK 248
V + K A V+VK+ ++
Sbjct: 2051 VEVTEEHKPSAVAHVVVKVIVE 2072
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/223 (27%), Positives = 99/223 (44%), Gaps = 28/223 (12%)
Query: 24 GGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQN 83
GG VN + P+Y V EN L A+D D GE G + +
Sbjct: 168 GGRRKRNVNTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDE-----GE-AGRLEYTMD 221
Query: 84 VPFDA-----VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
FD+ +D TG + + E+LD E + + F + A D G ++S A
Sbjct: 222 ALFDSRSNQFFSLDPVTG--AVTTAEELDRETKSTHVFRVTAQDHGMP------RRSALA 273
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEII-- 195
T+ I V D N++ PVF+++ YK ++ E + +L V A D D P + + Y ++
Sbjct: 274 TLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANIL--YRLLEG 331
Query: 196 ---TPDVPFTVD-KDGYIKNTEKLNYGKEHQYKLTVTAYDCGK 234
+P F +D + G I+ ++ + Y+LTV A D G+
Sbjct: 332 SGGSPSEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGR 374
Score = 58.5 bits (140), Expect = 3e-08
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G + LD E K+Y+ ++A D G+ P +NV V +QV D+N+ AP+F
Sbjct: 454 GALDVVSPLDYETTKEYTLRVRAQDGGR-PPLSNVS----GLVTVQVLDINDNAPIFVST 508
Query: 158 SYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDK-DGYIKNTEKL 215
++ATV+E +L V+A+DAD + D PFT++ G+I +L
Sbjct: 509 PFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAEL 568
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ + Y V A D G T V +++
Sbjct: 569 DREEVDFYSFGVEARDHGTPALTASASVSVTV 600
Score = 53.9 bits (128), Expect = 7e-07
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 10/141 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVIR++ +D E + Y T++A D G+ P +S A V + V D N+ AP F EK
Sbjct: 347 GVIRTRGPVDREEVESYQLTVEASDQGRDPG----PRSTTAAVFLSVEDDNDNAPQFSEK 402
Query: 158 SYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDV--PFTVD-KDGYIKNTE 213
Y V E + +LRV A D D + + Y I++ + F +D + G +
Sbjct: 403 RYVVQVREDVTPGAPVLRVTASDRDKGS--NAVVHYSIMSGNARGQFYLDAQTGALDVVS 460
Query: 214 KLNYGKEHQYKLTVTAYDCGK 234
L+Y +Y L V A D G+
Sbjct: 461 PLDYETTKEYTLRVRAQDGGR 481
Score = 50.4 bits (119), Expect = 8e-06
Identities = 51/182 (28%), Positives = 80/182 (43%), Gaps = 22/182 (12%)
Query: 81 GQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATV 140
G + PF + G G I +LD E YSF ++A D G + A+V
Sbjct: 548 GHDFPFTI-----NNGTGWISVAAELDREEVDFYSFGVEARDHG------TPALTASASV 596
Query: 141 HIQVNDVNEYAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ V DVN+ P F + Y + E S++ V AVD D + +Y+I + +
Sbjct: 597 SVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA----HSVITYQITSGNT 652
Query: 200 --PFTVDKD---GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPG 254
F++ G + L+Y E QY L VTA D G ++ T ++V ++ T P
Sbjct: 653 RNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASD-GTRQDTAQIVVNVTDANTHRPV 711
Query: 255 WQ 256
+Q
Sbjct: 712 FQ 713
Score = 49.3 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G + ++ +LD E Q Y+ I A D G +KS + I VNDVN+ AP F
Sbjct: 765 GAVTTQAELDYEDQVSYTLAITARDNGIP------QKSDTTYLEILVNDVNDNAPQFLRD 818
Query: 158 SYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYE-IITPDVPFTVDK-DGYIKNTEK 214
SY+ +V E + S+L++ A D D +++ D F V+ G ++ +
Sbjct: 819 SYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRR 878
Query: 215 LNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
L+ QY L A D G A + V +++
Sbjct: 879 LDRENVAQYVLRAYAVDKGMPPARTPMEVTVTV 911
Score = 47.4 bits (111), Expect = 7e-05
Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 13/159 (8%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+ +G G++ LD +L++ Y + A DGT + A + + V D N +
Sbjct: 658 ITSQSGGGLVSLALPLDYKLERQYVLAVTA------SDGT---RQDTAQIVVNVTDANTH 708
Query: 151 APVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GY 208
PVF+ Y V E + +++ + A D D E P F +D D G
Sbjct: 709 RPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQ--FRIDADTGA 766
Query: 209 IKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ +L+Y + Y L +TA D G + ++ ++I +
Sbjct: 767 VTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILV 805
Score = 45.1 bits (105), Expect = 3e-04
Identities = 55/204 (26%), Positives = 87/204 (42%), Gaps = 18/204 (8%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN + P +L +Y G V E+ + A D+D+ L G + G + D +
Sbjct: 808 VNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLN--GRVFYTFQGGDDGDGDFI 865
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V S G++R+ +LD E Y A D G P T ++ V + V DVN+
Sbjct: 866 VESTS---GIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPME------VTVTVLDVND 916
Query: 150 YAPVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-- 206
PVF++ + V E ++ RV A D D +QI Y+I+ ++P D
Sbjct: 917 NPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTN-AQI-MYQIVEGNIPEVFQLDIF 974
Query: 207 -GYIKNTEKLNYGKEHQYKLTVTA 229
G + L+Y +Y L + A
Sbjct: 975 SGELTALVDLDYEDRPEYVLVIQA 998
Score = 35.4 bits (80), Expect = 0.26
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 886 GKENEMDWD---DSALTITVNPMETYEDQHSSEEEEEEEEEEE 925
G++ + D D DS L++ + +Y HSS+ EEEEEEEEE
Sbjct: 2709 GQDQQHDPDTDSDSDLSLEDDQSGSYASTHSSDSEEEEEEEEE 2751
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 57.4 bits (137), Expect = 6e-08
Identities = 48/160 (30%), Positives = 77/160 (48%), Gaps = 13/160 (8%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D+ TG+ + + LD E + Y I+A D G P + K + I V DVN+
Sbjct: 2614 IDQLTGQ--VSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEK------LDITVLDVNDN 2665
Query: 151 APVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDV--PFTVD-KDG 207
AP+FKE + + ++E IL V A+D D P YEI+ ++ F+++ G
Sbjct: 2666 APIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQ--LDYEIVNGNMENSFSINHATG 2723
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
I++ L+ K Y LT+ + D G + V V I+I
Sbjct: 2724 EIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINI 2763
Score = 54.7 bits (130), Expect = 4e-07
Identities = 46/144 (31%), Positives = 65/144 (45%), Gaps = 13/144 (9%)
Query: 95 TGEGV---IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYA 151
+GEG + SK LD E+ Y ++ D G+ K+ V++ V D+N+
Sbjct: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEP------KRRGYLQVNVTVQDINDNP 247
Query: 152 PVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GYI 209
PVF Y+A V E S+L+V A DAD Y + PF +D + G I
Sbjct: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNAD--IRYRLQDEGTPFQMDPETGLI 305
Query: 210 KNTEKLNYGKEHQYKLTVTAYDCG 233
E L++ QY LTV A D G
Sbjct: 306 TVREPLDFEARRQYSLTVQAMDRG 329
Score = 52.8 bits (125), Expect = 2e-06
Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 94 STGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPV 153
++ G++ + LD EL + + TI A D G V ++ +V + V DVN+ +PV
Sbjct: 3140 NSSTGILTLAKALDYELCQKHEMTISAIDGGW------VARTGYCSVTVNVIDVNDNSPV 3193
Query: 154 FKEKSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVP-FTVDKD-GYIK 210
F Y TV+E +++ + A DAD + + +Y + + D F +D + G I
Sbjct: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADSGT--NAVIAYTVQSSDSDLFVIDPNTGVIT 3251
Query: 211 NTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
L++ + Y LTV A++ + V I +K T
Sbjct: 3252 TQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGT 3291
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/204 (26%), Positives = 89/204 (43%), Gaps = 18/204 (8%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN H P + P Y + E+ L ++A D D+ + GEI + N +
Sbjct: 1834 VNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVN--GEIT----YIVNEDDEDG 1887
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ + GV LD E+Q+ Y T++A D G T ++ V+ + DVN+
Sbjct: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAED--GGGQFTTIR------VYFNILDVND 1939
Query: 150 YAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDV--PFTVDKDG 207
P+F SY +++E S + V V D + +Y I + D FTVDK+G
Sbjct: 1940 NPPIFSLNSYSTSLMENLPVGSTVLVFNV-TDADDGINSQLTYSIASGDSLGQFTVDKNG 1998
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYD 231
+K + L+ + Y L V +D
Sbjct: 1999 VLKVLKALDRESQSFYNLVVQVHD 2022
Score = 52.0 bits (123), Expect = 3e-06
Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 12/145 (8%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G I + LD E Y T+QA D G P ++ +TV I + D+N++ PVF+
Sbjct: 2209 GAITVAKPLDREKTPTYHLTVQATDRGSTP------RTDTSTVSIVLLDINDFVPVFELS 2262
Query: 158 SYKATVIE--GKQYDSILRVEAVDADCSPQFSQICSYEII--TPDVPFTVDKDGYIKNTE 213
Y V E G +IL+V A D D + SY + D FT+ G + T+
Sbjct: 2263 PYSVNVPENLGTLPRTILQVVARDDDRGS--NSKLSYVLFGGNEDNAFTLSASGELGVTQ 2320
Query: 214 KLNYGKEHQYKLTVTAYDCGKKRAT 238
L+ + ++ L +TA D G T
Sbjct: 2321 SLDRETKERFVLMITATDSGSPALT 2345
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 21/143 (14%)
Query: 114 YSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE-GKQYDSI 172
+SFT+ A D G +ATVH+ + D+N+ AP F + Y+AT+ E +
Sbjct: 1175 FSFTVIATD-----QGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQV 1229
Query: 173 LRVEAVDADCSPQFSQICSYEII--TPDVPFTVDK-DGYIKNTEKLNYGKEHQYKLTVTA 229
LRV A D D + + Y II + F +D G + KL+Y Y L + A
Sbjct: 1230 LRVSASDVD--EGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQA 1287
Query: 230 YDCGKKRATEDVLVKISIKPTCT 252
D G I + TCT
Sbjct: 1288 VDSG----------TIPLNSTCT 1300
Score = 47.8 bits (112), Expect = 5e-05
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D ++G+ + K LD E YS IQA D G P + T++I + D N+
Sbjct: 1260 IDSTSGQVTLIGK--LDYEATPAYSLVIQAVDSGTIPLNST------CTLNIDILDENDN 1311
Query: 151 APVFKEKSYKATVIEGKQYDSILR-VEAVDADCSPQFSQICSYEIITPDVPFTVDKD-GY 208
P F + + V+E + ++ V A D+D S F++ + G
Sbjct: 1312 TPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGS 1371
Query: 209 IKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK------PTCTPG 254
I +KL++ + YKL +TA D G+ + + V I ++ P+ PG
Sbjct: 1372 IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPG 1423
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 12/140 (8%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G I L +L +++ T+ A D G P S +ATVHI V + N + P F +
Sbjct: 3039 GWISVASSLISDLNQNFFITVTAKDKGNPP------LSSQATVHITVTEENYHTPEFSQS 3092
Query: 158 SYKATVIEGKQYDSILR-VEAVDADCSPQFSQICSYEIITPDVP--FTVDKD-GYIKNTE 213
AT+ E SI+R V A D D + + + Y I + + F ++ G + +
Sbjct: 3093 HMSATIPESHSIGSIVRTVSARDRDAA--MNGLIKYSISSGNEEGIFAINSSTGILTLAK 3150
Query: 214 KLNYGKEHQYKLTVTAYDCG 233
L+Y ++++T++A D G
Sbjct: 3151 ALDYELCQKHEMTISAIDGG 3170
Score = 45.4 bits (106), Expect = 3e-04
Identities = 58/219 (26%), Positives = 88/219 (40%), Gaps = 30/219 (13%)
Query: 49 NDNTVLLDPPL--IALDKDAPL--RFAGEICGFKIHGQNVPFDAVVVDKSTGE------- 97
NDN+ + D + L + P+ RF K G N + + +TG+
Sbjct: 990 NDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD 1049
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G + K +LD ELQ Y + A D P V V + + DVN+ P+F
Sbjct: 1050 GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVN------VTVILEDVNDNRPLFNST 1103
Query: 158 SYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLN 216
+Y E ++ S + +V AVD D P S+E++ PD G I NT + +
Sbjct: 1104 NYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHA-ISGEITNTHQFD 1162
Query: 217 YGKEHQ------YKLTVTAYDCG-----KKRATEDVLVK 244
+ + TV A D G K +AT V +K
Sbjct: 1163 RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMK 1201
Score = 45.1 bits (105), Expect = 3e-04
Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 11/156 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G + + LD E Q YS + A D G P +S A +++ + D+N+ +PVF
Sbjct: 639 GRLSTISSLDREEQAFYSLLVLATDLGSPP------QSSMARINVSLLDINDNSPVFYPV 692
Query: 158 SYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPD-VPFTVD-KDGYIKNTEK 214
Y A + E + S I V A D D + Y I D F V+ + G I
Sbjct: 693 QYFAHIKENEPGGSYITTVSATDPDLGT--NGTVKYSISAGDRSRFQVNAQSGVISTRMA 750
Query: 215 LNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
L+ ++ Y+L + A D G ++ +V I++ T
Sbjct: 751 LDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDT 786
Score = 44.7 bits (104), Expect = 4e-04
Identities = 62/231 (26%), Positives = 99/231 (42%), Gaps = 18/231 (7%)
Query: 22 CGGGVWAARVNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIH 80
C V VN + P +L Y V EN + L A D D+ + + +
Sbjct: 3178 CSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSG---TNAVIAYTV- 3233
Query: 81 GQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATV 140
Q+ D V+D +TG VI ++ LD E ++ Y T++A++ PD ++ ATV
Sbjct: 3234 -QSSDSDLFVIDPNTG--VITTQGFLDFETKQSYHLTVKAFNV---PDE---ERCSFATV 3284
Query: 141 HIQVNDVNEYAPVFKEKSYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITPDV 199
+IQ+ NEY P F K Y + E +I+ V A D D +
Sbjct: 3285 NIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKK 3344
Query: 200 PFTVD-KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRAT--EDVLVKISI 247
F ++ K G I + L+ KE + L V A + G R ++V V +++
Sbjct: 3345 GFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTV 3395
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 23/167 (13%)
Query: 77 FKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSH 136
+++ + PF +D TG +I +E LD E ++ YS T+QA D G P T
Sbjct: 287 YRLQDEGTPFQ---MDPETG--LITVREPLDFEARRQYSLTVQAMDRGV-PSLTG----- 335
Query: 137 KATVHIQVNDVNEYAPVFKEKSYKAT-----VIEGKQYDSILRVEAVDADCSPQFSQICS 191
+A IQ+ DVN+ PV K + + AT V E Q +++ + V SP + S
Sbjct: 336 RAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNIS 395
Query: 192 YEII--TPDVPFTVDKD-----GYIKNTEKLNYGKEHQYKLTVTAYD 231
+I+ F V IK L+ + Y LTV+ D
Sbjct: 396 VQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSD 442
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/155 (29%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
Query: 95 TGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVF 154
T +G +R +LD E +Y+ T+ A D G+ S V + V D+N+ P+F
Sbjct: 2101 TIDGEVRLTGELDREEVSNYTLTVVATDKGQP------SLSSSTEVVVMVLDINDNNPIF 2154
Query: 155 KEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDV--PFTVDK-DGYIK 210
+ YK + E + I++V A D D Q+ Y I+ + F +D G I
Sbjct: 2155 AQALYKVEINENTLTGTDIIQVFAADGDEGTN-GQV-RYGIVNGNTNQEFRIDSVTGAIT 2212
Query: 211 NTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKI 245
+ L+ K Y LTV A D G T+ V I
Sbjct: 2213 VAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 95 TGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVF 154
+ G + + LD E ++ + I A D G P T T+++ V+DVN+ P F
Sbjct: 2311 SASGELGVTQSLDRETKERFVLMITATDSGS-PALTGT-----GTINVIVDDVNDNVPTF 2364
Query: 155 KEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVD-KDGYIKNT 212
K+Y T+ E + +L V A DAD S II + FT++ G I +
Sbjct: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKN----AVIRIIGGNSQFTINPSTGQIITS 2420
Query: 213 EKLNYGKEHQYKLTVTAYDCGKKR---ATEDVLVKIS 246
L+ + Y L V D G ++ VLV ++
Sbjct: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVT 2457
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 3/138 (2%)
Query: 46 VTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEK 105
V EN + L D D+P G I + G V K +I+
Sbjct: 367 VDENAQVGTVVALLTVTDADSPAA-NGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASA 425
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVK-KSHKATVHIQVNDVNEYAPVFKEKSYKATVI 164
LD E Y+ T+ D P G V+ +S A++ I VND+N++ PVF ++ Y+ +
Sbjct: 426 LDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
Query: 165 EGKQYDS-ILRVEAVDAD 181
E S + + A D D
Sbjct: 486 EEAPPGSYVSGISATDGD 503
Score = 39.7 bits (91), Expect = 0.014
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 15/154 (9%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVI ++ LD E + Y I A DG N++ ++A V I V D + PVF +
Sbjct: 743 GVISTRMALDREEKTAYQLQIVA------TDGGNLQSPNQAIVTITVLDTQDNPPVFSQV 796
Query: 158 SYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVP--FTVDK-DGYIKNTEK 214
+Y V E V +V A S I SY I T D F +++ G +
Sbjct: 797 AYSFVVFENVALG--YHVGSVSASTMDLNSNI-SYLITTGDQKGMFAINQVTGQLTTANV 853
Query: 215 LNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIK 248
++ ++ Y+L V A T D +V I++K
Sbjct: 854 IDREEQSFYQLKVVA---SGGTVTGDTMVNITVK 884
Score = 39.3 bits (90), Expect = 0.018
Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 30/201 (14%)
Query: 55 LDPPLIALDKDAPLRFAGEICGFKI--------HGQNVPFDAVVV-----DKSTGE---- 97
LD P+ K + GE G + G P + +V +K+ G
Sbjct: 1624 LDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTI 1683
Query: 98 ----GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPV 153
G+I++ LD E Q + + Y K T ++ +A V I + D+N+ PV
Sbjct: 1684 GRHTGIIQTAAILDRE-QGACLYLVDVYAIEKS---TAFPRTQRAEVEITLQDINDNPPV 1739
Query: 154 FKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIIT-PDVPFTVD-KDGYIK 210
F TV E I+++ A+DAD + + +Y II+ D F +D + G +
Sbjct: 1740 FPTDMLDLTVEENIGDGSKIMQLTAMDAD--EGANALVTYTIISGADDSFRIDPESGDLI 1797
Query: 211 NTEKLNYGKEHQYKLTVTAYD 231
T +L+ + +Y L V A D
Sbjct: 1798 ATRRLDRERRSKYSLLVRADD 1818
Score = 37.4 bits (85), Expect = 0.069
Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 135 SHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYE 193
S + + V+DVN+ +PVF + SY+ T+ E + +S +V+A D D +
Sbjct: 977 SSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIA 1036
Query: 194 IITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
F + DG + +L+ + +Y L V A D RA E + +++
Sbjct: 1037 EGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASD----RAVEPLSATVNV 1086
Score = 36.6 bits (83), Expect = 0.12
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 15/162 (9%)
Query: 87 DAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
D+ +D +G+ + + +LD E + YS ++A D + D ++I V+D
Sbjct: 1785 DSFRIDPESGDLI--ATRRLDRERRSKYSLLVRADDGLQSSD---------MRINITVSD 1833
Query: 147 VNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPD---VPFTV 203
VN++ P F Y + E S++ D S +I +Y + D + F
Sbjct: 1834 VNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEI-TYIVNEDDEDGIFFLN 1892
Query: 204 DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKI 245
G T L+Y + Y LTV A D G + T V I
Sbjct: 1893 PITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNI 1934
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 56.2 bits (134), Expect = 1e-07
Identities = 60/220 (27%), Positives = 96/220 (43%), Gaps = 20/220 (9%)
Query: 31 VNKHKP-WLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN + P + +PTY + E+ L A D+DA + +++ G N +
Sbjct: 680 VNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDA-----NSVITYQLTGGNTR-NRF 733
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
+ G G+I LD + ++ Y + A DGT +SH A V I V D N
Sbjct: 734 ALSSQRGGGLITLALPLDYKQEQQYVLAVTA------SDGT---RSHTAHVLINVTDANT 784
Query: 150 YAPVFKEKSYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD-G 207
+ PVF+ Y +V E + SI + A D D + +Y I P F +D D G
Sbjct: 785 HRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGE--NARITYVIQDPVPQFRIDPDSG 842
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ +L+Y + Y LT+ A D G + ++ ++I I
Sbjct: 843 TMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILI 882
Score = 55.5 bits (132), Expect = 2e-07
Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 18/208 (8%)
Query: 32 NKHKPWLEPT-YHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
N H P E + Y V EN + A D+D+P+ + +D
Sbjct: 347 NDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPIN-----ANLRYRVLGGAWDVFQ 401
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+++S+G V+ ++ LD E +Y ++A D G+ P S ATV+I+V D N+
Sbjct: 402 LNESSG--VVSTRAVLDREEAAEYQLLVEANDQGRNPGPL----SATATVYIEVEDENDN 455
Query: 151 APVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVP---FTVDKD 206
P F E++Y V E + ++LRV+A D D + Y I++ +V +
Sbjct: 456 YPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQ--NAAIHYSILSGNVAGQFYLHSLS 513
Query: 207 GYIKNTEKLNYGKEHQYKLTVTAYDCGK 234
G + L++ +Y L++ A D G+
Sbjct: 514 GILDVINPLDFEDVQKYSLSIKAQDGGR 541
Score = 52.8 bits (125), Expect = 2e-06
Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 17/158 (10%)
Query: 105 KLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI 164
+LD E + YSF ++A D G P S +V I V DVN+ PVF + +Y+ +
Sbjct: 644 ELDREEVEHYSFGVEAVDHGSPP------MSSSTSVSITVLDVNDNDPVFTQPTYELRLN 697
Query: 165 EGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDV--PFTVDKD---GYIKNTEKLNYG 218
E S+L ++A D D + + +Y++ + F + G I L+Y
Sbjct: 698 EDAAVGSSVLTLQARDRDA----NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYK 753
Query: 219 KEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQ 256
+E QY L VTA D G + T VL+ ++ T P +Q
Sbjct: 754 QEQQYVLAVTASD-GTRSHTAHVLINVTDANTHRPVFQ 790
Score = 51.2 bits (121), Expect = 5e-06
Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 28/171 (16%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ LD E + YS +I+A D G+ P + V +QV DVN+ P+F
Sbjct: 514 GILDVINPLDFEDVQKYSLSIKAQDGGRPP-----LINSSGVVSVQVLDVNDNEPIFVSS 568
Query: 158 SYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEII-------------------TP 197
++ATV+E ++ ++AVDAD + Y ++ TP
Sbjct: 569 PFQATVLENVPLGYPVVHIQAVDADSGE--NARLHYRLVDTASTFLGGGSAGPKNPAPTP 626
Query: 198 DVPFTV-DKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
D PF + + G+I +L+ + Y V A D G + V I++
Sbjct: 627 DFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITV 677
Score = 44.3 bits (103), Expect = 6e-04
Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 30/212 (14%)
Query: 32 NKHKPWLEPTYHGIVTENDNTVLLD-PPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
N H+P + +++ + D V L A D+D G+N V+
Sbjct: 783 NTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDT--------------GENARITYVI 828
Query: 91 VDK------STGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQV 144
D G + + +LD E Q Y+ TI A D G +KS T+ I +
Sbjct: 829 QDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIP------QKSDTTTLEILI 882
Query: 145 NDVNEYAPVFKEKSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYE-IITPDVPFT 202
D N+ AP F Y+ ++ E SIL+V A D D P + +++ D F
Sbjct: 883 LDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFY 942
Query: 203 VD-KDGYIKNTEKLNYGKEHQYKLTVTAYDCG 233
++ G I+ +L+ Y L A D G
Sbjct: 943 IEPTSGVIRTQRRLDRENVAVYNLWALAVDRG 974
Score = 40.8 bits (94), Expect = 0.006
Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D +TG + + LD E ++ + ++A D P +S + + V D N++
Sbjct: 298 IDSATG--AVSTDSVLDRETKETHVLRVKAVDYSTPP------RSATTYITVLVKDTNDH 349
Query: 151 APVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEII--TPDVPFTVDKDG 207
+PVF++ Y+ V E + +L + A D D SP + + Y ++ DV + G
Sbjct: 350 SPVFEQSEYRERVRENLEVGYEVLTIRASDRD-SPINANL-RYRVLGGAWDVFQLNESSG 407
Query: 208 YIKNTEKLNYGKEHQYKLTVTAYDCGKK----RATEDVLVKI 245
+ L+ + +Y+L V A D G+ AT V +++
Sbjct: 408 VVSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEV 449
Score = 40.8 bits (94), Expect = 0.006
Identities = 45/165 (27%), Positives = 78/165 (47%), Gaps = 13/165 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVIR++ +LD E Y+ A D G+ S + + + D+N+ AP+F++
Sbjct: 948 GVIRTQRRLDRENVAVYNLWALAVD-----RGSPTPLSASVEIQVTILDINDNAPMFEKD 1002
Query: 158 SYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITPDVP--FTVD-KDGYIKNTE 213
+ V E S++ ++ A D D P +QI Y+I+ D+ F +D +G ++
Sbjct: 1003 ELELFVEENNPVGSVVAKIRANDPDEGPN-AQI-MYQIVEGDMRHFFQLDLLNGDLRAMV 1060
Query: 214 KLNYGKEHQYKLTVTAYDCG-KKRATEDV-LVKISIKPTCTPGWQ 256
+L++ +Y L V A RAT + LV + P P +Q
Sbjct: 1061 ELDFEVRREYVLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQ 1105
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 55.5 bits (132), Expect = 2e-07
Identities = 83/335 (24%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 31 VNKHKPWL-EPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAV 89
VN+H+P + Y V EN + + A D+D PL +I I G + +
Sbjct: 3314 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLN--SDITYSLIGGNQLGHFTI 3371
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKAT-VHIQVNDVN 148
K G ++ + LD E YS ++A D G+ P H+ T + IQV DVN
Sbjct: 3372 HPKK----GELQVAKALDREQASSYSLKLRATDSGQPP-------LHEDTDIAIQVADVN 3420
Query: 149 EYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIITPD--VPFTVDK 205
+ P F + +Y TV E S +L++ D D SP+ S+ I + F V
Sbjct: 3421 DNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPD-SPENGPPYSFRITKGNNGSAFRVTP 3479
Query: 206 DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYE 265
DG++ E L+ + Y+L + A D G + V++ + + Y
Sbjct: 3480 DGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHV-----------TEQSHYA 3528
Query: 266 PGTGALAVFPNIHLETCDEPVASVQATVELETSHIGK--GCDRDTYSEKSLHRLCGAAAG 323
P L +F + + E + +GK DRD + G
Sbjct: 3529 PSALPLEIFITVGED-------------EFQGGMVGKIHATDRDPQDTLTYSLAEEETLG 3575
Query: 324 TAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGT 358
+ +P G + GLP GH S V +GT
Sbjct: 3576 RHFSVGAPDGKIIAAQGLP--RGHYSFNVTVSDGT 3608
Score = 53.1 bits (126), Expect = 1e-06
Identities = 47/158 (29%), Positives = 80/158 (50%), Gaps = 16/158 (10%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
GVI+ ++ +D E K Y + A+ C + D ++ +V+IQV DVN+ PVF+
Sbjct: 2747 GVIKVRKPMDHESTKLYQIDVMAH-CLQNTDVVSL-----VSVNIQVGDVNDNRPVFEAD 2800
Query: 158 SYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIK 210
YKA + E S+++V A+D D + + Q+ SY + F +D + G+I
Sbjct: 2801 PYKAVLTENMPVGTSVIQVTAIDKD-TGRDGQV-SYRLSADPGSNVHELFAIDSESGWIT 2858
Query: 211 NTEKLNYGKEHQYKLTVTAYDCGKK-RATEDVLVKISI 247
++L+ Y V AYD G+ + + LV++SI
Sbjct: 2859 TLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSI 2896
Score = 49.3 bits (116), Expect = 2e-05
Identities = 57/225 (25%), Positives = 98/225 (43%), Gaps = 29/225 (12%)
Query: 32 NKHKPWLEPTYHGI-VTENDNTVLLDPPLIALDKDAP--LRFAGEICGFKIHGQNVPFDA 88
NK P + Y+ + V EN + L P++ +P LR I + P
Sbjct: 2165 NKSNPLFQSPYYKVRVPEN---ITLYTPILHTQARSPEGLRLIYNIV------EEEPLML 2215
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
D TG V+ LD E + + FT++A D G +ATV + V DVN
Sbjct: 2216 FTTDFKTG--VLTVTGPLDYESKTKHVFTVRATDTALG-------SFSEATVEVLVEDVN 2266
Query: 149 EYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIIT--PDVP--FTV 203
+ P F + Y ++ EG + ++++ A D D ++ SY+I+ DV F +
Sbjct: 2267 DNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGR--NRDVSYQIVEDGSDVSKFFQI 2324
Query: 204 D-KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
+ G + ++L+Y + + + V A D G T + LV +++
Sbjct: 2325 NGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNV 2369
Score = 45.8 bits (107), Expect = 2e-04
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 12/154 (7%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G++ LD E Y +I+ C + + S TV + + DVNE+ P F +
Sbjct: 3271 GILYVNASLDFETSPKYFLSIE---CSRKSSSS---LSDVTTVMVNITDVNEHRPQFPQD 3324
Query: 158 SYKATVIEGKQY-DSILRVEAVDADCSPQFSQICSYEIITPDV--PFTV-DKDGYIKNTE 213
Y V+E D IL V A D D P S I +Y +I + FT+ K G ++ +
Sbjct: 3325 PYSTRVLENALVGDVILTVSATDED-GPLNSDI-TYSLIGGNQLGHFTIHPKKGELQVAK 3382
Query: 214 KLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
L+ + Y L + A D G+ ED + I +
Sbjct: 3383 ALDREQASSYSLKLRATDSGQPPLHEDTDIAIQV 3416
Score = 43.5 bits (101), Expect = 0.001
Identities = 49/172 (28%), Positives = 83/172 (48%), Gaps = 19/172 (11%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
++ STGE + + ++LD E Q+ + ++A D G P + + V + V+D+N+
Sbjct: 2324 INGSTGE--MSTVQELDYEAQQHFHVKVRAMDKGDPP------LTGETLVVVNVSDINDN 2375
Query: 151 APVFKEKSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIIT--PDVPFTVDKDG 207
P F++ Y+A V E +L+V+A+D D S S++ Y I++ D F ++
Sbjct: 2376 PPEFRQPQYEANVSELATCGHLVLKVQAIDPD-SRDTSRL-EYLILSGNQDRHFFINSSS 2433
Query: 208 YIKNTEKLNYGKEH---QYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQ 256
I N K+H Y L V A D G RAT V + + +P +Q
Sbjct: 2434 GI--ISMFNLCKKHLDSSYNLRVGASD-GVFRATVPVYINTTNANKYSPEFQ 2482
Score = 38.1 bits (87), Expect = 0.040
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 15/226 (6%)
Query: 29 ARVNKHKPWLEPTYHGIVTENDNTVLLDPPLI-ALDKDAPLRFAGEICGFKIHGQNVPFD 87
A +N H+P T + + D ++ + A+D+D G+ + IHG P
Sbjct: 1439 ANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDK-----GKSLIYTIHGSQDPGS 1493
Query: 88 AVVVDKSTGEGVIRSKEKLDCEL-QKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVND 146
A + GV+ + KLD ++ T+ D +K++ V I V D
Sbjct: 1494 ASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRD-----QEIPIKRNF-VWVTIHVED 1547
Query: 147 VNEYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDK 205
N + P F + Y+A+V + +L+V A+DAD S + F ++
Sbjct: 1548 GNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINA 1607
Query: 206 D-GYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
G I +KL+ + LTV A D G + + V I + P+
Sbjct: 1608 LLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPS 1653
Score = 37.7 bits (86), Expect = 0.053
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 6/125 (4%)
Query: 128 DGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQ-YDSILRVEAVDADCSPQF 186
D ++ + V + + DVN+ P FK Y + +G + D + +V A D D
Sbjct: 2044 DNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGT-- 2101
Query: 187 SQICSYEIITPDVPFTVDKD-GYIKNTEKLNYGKEHQYKLTVTAYDCG--KKRATEDVLV 243
+ +YE F +D G I + +Y ++Y L V A D G ++ E+VLV
Sbjct: 2102 NGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLV 2161
Query: 244 KISIK 248
+ K
Sbjct: 2162 TVRNK 2166
Score = 35.0 bits (79), Expect = 0.34
Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPD 198
V I + D N +AP+F SY T+ E S+L V A D D + +Y I P
Sbjct: 444 VVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGE--NGYVTYSIAGPK 501
Query: 199 -VPFTVDKD-GYIKNTEKLNYG-KEHQYKLTVTAYDCGKK-RATEDVLVKISIK 248
+PF++D G I ++ ++Y + Y V A D G R ++V + + ++
Sbjct: 502 ALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLR 555
Score = 33.9 bits (76), Expect = 0.76
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 9/108 (8%)
Query: 137 KATVHIQVN--DVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYE 193
+ATV + +N + N+Y+P F++ Y+A + E + ++ + A+D D P + Y
Sbjct: 2462 RATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGT--IDYT 2519
Query: 194 IIT--PDVPFTVDKDGYIKNTEKLN--YGKEHQYKLTVTAYDCGKKRA 237
II F+++ +G I +KL+ E + V A D G + A
Sbjct: 2520 IINKLASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVA 2567
Score = 33.9 bits (76), Expect = 0.76
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 11/135 (8%)
Query: 31 VNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
VN + P P+ H V DNT + P + +D ++ F
Sbjct: 3106 VNDNAPRFFPS-HCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFS--- 3161
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D +TG VIR ++ L Q T++A D GT + S TV + V + +Y
Sbjct: 3162 IDATTG--VIRLEKPLQVRPQAPLELTVRASDL-----GTPIPLSTLGTVTVSVVGLEDY 3214
Query: 151 APVFKEKSYKATVIE 165
PVF + V E
Sbjct: 3215 LPVFLNTEHSVQVPE 3229
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 11/132 (8%)
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE 165
L+ E++ Y+ IQA + ++ V + + D N+ P+F SY+ T+ E
Sbjct: 107 LNREVRDSYTLIIQATE-------KTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISE 159
Query: 166 GKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTV-DKDGYIKNTEKLNYGKEHQY 223
S I +V A DAD Y T F + G + KLN ++
Sbjct: 160 DMPLKSPICKVTATDADLGQNAE--FYYAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKH 217
Query: 224 KLTVTAYDCGKK 235
+L V A D +K
Sbjct: 218 ELQVLAVDRMRK 229
Score = 32.7 bits (73), Expect = 1.7
Identities = 44/154 (28%), Positives = 72/154 (46%), Gaps = 19/154 (12%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEK 157
G+I +KLD ++ T++A D G P ++ ATV I V + AP+F +
Sbjct: 1610 GIITLAQKLDQANHAPHTLTVKAEDQGS-PQWHDL-----ATVIIHVYPSDRSAPIFSKS 1663
Query: 158 SYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEII--TPDVPFTVDK-DGYIKNTE 213
Y + E S IL V A+ SP S++ +YE+ D F+++ G I +
Sbjct: 1664 EYFVEIPESIPVGSPILLVSAM----SP--SEV-TYELREGNKDGVFSMNSYSGLISTQK 1716
Query: 214 KLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
KL++ K Y+L + + A DV+V + I
Sbjct: 1717 KLDHEKISSYQLKIRGSNMA--GAFTDVMVVVDI 1748
Score = 31.6 bits (70), Expect = 3.8
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 40 PTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGV 99
P Y I+ +N+N ++ A D D + A + +KI +D S G
Sbjct: 1772 PLYSMIMDKNNNPFVIH----ASDSD---KEANSLLVYKILEPEA-LKFFKIDPSMGTLT 1823
Query: 100 IRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSY 159
I S+ +D E + F + +D G + A V I V DVN+ P F E+ Y
Sbjct: 1824 IVSE--MDYESMPSFQFCVYVHDQGSPV----LFAPRPAQVIIHVRDVNDSPPRFSEQIY 1877
Query: 160 KATVIEGKQYD--SILRVEAVDADCSPQFS 187
+ ++ G + +L V A D D +S
Sbjct: 1878 EVAIV-GPIHPGMELLMVRASDEDSEVNYS 1906
Score = 30.4 bits (67), Expect = 8.4
Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 16/157 (10%)
Query: 131 NVKKSHKATVHIQVNDVNEYAPVFKEKSYKAT-VIEGKQYDSIL-RVEAVDADCSPQFSQ 188
N + S + + +N Y P F++ ++ V+E ++ L R+ A D D F+
Sbjct: 691 NQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAG--FNG 748
Query: 189 ICSYEIITPDVPFTVD---KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKI 245
Y I + D + G + L+Y + Y L VT YD G + + L+ +
Sbjct: 749 KLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTV 808
Query: 246 SIKPTCTPGWQGWN-NRIEYEPGTGALAVFPNIHLET 281
++K WN N + PG L + + + T
Sbjct: 809 NVK--------DWNDNAPRFPPGGYQLTISEDTEVGT 837
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 55.1 bits (131), Expect = 3e-07
Identities = 54/178 (30%), Positives = 74/178 (41%), Gaps = 22/178 (12%)
Query: 78 KIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHK 137
K G F +VV+KS LD E Q YSF I A D G P V S
Sbjct: 179 KTRGDGSRFAELVVEKS-----------LDRETQSHYSFRITALDGGDPPRLGTVGLS-- 225
Query: 138 ATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIIT 196
I+V D N+ PVF E +Y +V E ++ ++R+ A D D + S+
Sbjct: 226 ----IKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYV 281
Query: 197 PDVP---FTVDK-DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
D F +D G + T L+Y + H Y+L V A D G V +S+ T
Sbjct: 282 NDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDT 339
Score = 37.7 bits (86), Expect = 0.053
Identities = 53/238 (22%), Positives = 91/238 (38%), Gaps = 41/238 (17%)
Query: 32 NKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVP-FDAVV 90
+ H + +P Y IV EN+ + A D D L + +++P F V
Sbjct: 448 DNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVS 507
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
++ ++G+ I + + E K + F + A D G +N ATV + + DVN+
Sbjct: 508 INPNSGD--IYALRSFNHEQTKAFEFKVLAKDGGLPSLQSN------ATVRVIILDVNDN 559
Query: 151 APVFKEK-----------------SYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYE 193
PV Y TV++ + YD +Y+
Sbjct: 560 TPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV-------------TYD 606
Query: 194 IITPDVPF-TVDK-DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKP 249
+ D F +D+ +G ++ T + Y+L V A+D GK + LV I + P
Sbjct: 607 MTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSP 664
Score = 32.0 bits (71), Expect = 2.9
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 17/152 (11%)
Query: 105 KLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI 164
+LD E Y+ TIQA D G + +S K+ + + D N+ P F + Y+ V
Sbjct: 410 RLDREQHDQYNLTIQARD-----GGVPMLQSAKSFT-VLITDENDNHPHFSKPYYQVIVQ 463
Query: 165 EGKQYDS-ILRVEAVDADCSPQFSQICSYEII---TPDVP-FTV----DKDGYIKNTEKL 215
E + +L V A D D S SY+I+ D+P FT G I
Sbjct: 464 ENNTPGAYLLSVSARDPDLGLNGS--VSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSF 521
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
N+ + ++ V A D G + V++ I
Sbjct: 522 NHEQTKAFEFKVLAKDGGLPSLQSNATVRVII 553
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 55.1 bits (131), Expect = 3e-07
Identities = 54/178 (30%), Positives = 74/178 (41%), Gaps = 22/178 (12%)
Query: 78 KIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHK 137
K G F +VV+KS LD E Q YSF I A D G P V S
Sbjct: 179 KTRGDGSRFAELVVEKS-----------LDRETQSHYSFRITALDGGDPPRLGTVGLS-- 225
Query: 138 ATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQFSQICSYEIIT 196
I+V D N+ PVF E +Y +V E ++ ++R+ A D D + S+
Sbjct: 226 ----IKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYV 281
Query: 197 PDVP---FTVDK-DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPT 250
D F +D G + T L+Y + H Y+L V A D G V +S+ T
Sbjct: 282 NDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDT 339
Score = 37.7 bits (86), Expect = 0.053
Identities = 53/238 (22%), Positives = 91/238 (38%), Gaps = 41/238 (17%)
Query: 32 NKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVP-FDAVV 90
+ H + +P Y IV EN+ + A D D L + +++P F V
Sbjct: 448 DNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVS 507
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
++ ++G+ I + + E K + F + A D G +N ATV + + DVN+
Sbjct: 508 INPNSGD--IYALRSFNHEQTKAFEFKVLAKDGGLPSLQSN------ATVRVIILDVNDN 559
Query: 151 APVFKEK-----------------SYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYE 193
PV Y TV++ + YD +Y+
Sbjct: 560 TPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV-------------TYD 606
Query: 194 IITPDVPF-TVDK-DGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKP 249
+ D F +D+ +G ++ T + Y+L V A+D GK + LV I + P
Sbjct: 607 MTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSP 664
Score = 32.0 bits (71), Expect = 2.9
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 17/152 (11%)
Query: 105 KLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI 164
+LD E Y+ TIQA D G + +S K+ + + D N+ P F + Y+ V
Sbjct: 410 RLDREQHDQYNLTIQARD-----GGVPMLQSAKSFT-VLITDENDNHPHFSKPYYQVIVQ 463
Query: 165 EGKQYDS-ILRVEAVDADCSPQFSQICSYEII---TPDVP-FTV----DKDGYIKNTEKL 215
E + +L V A D D S SY+I+ D+P FT G I
Sbjct: 464 ENNTPGAYLLSVSARDPDLGLNGS--VSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSF 521
Query: 216 NYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
N+ + ++ V A D G + V++ I
Sbjct: 522 NHEQTKAFEFKVLAKDGGLPSLQSNATVRVII 553
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 54.7 bits (130), Expect = 4e-07
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 905 METYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQL 962
+E ++ EEEEE+EEEEE E+ EEED+ E E EEEE Q P T+ Q +
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Score = 47.0 bits (110), Expect = 9e-05
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Query: 887 KENEMDWDDSALTITVNPMETYED-----QHSSEEEEEEEEEEESEDGEEEDDITSAESE 941
+EN + + ++ +P E ED + EEEEEEEEEEE E+GEEE+ + E +
Sbjct: 1322 EENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKD 1381
Query: 942 SSEEEEGEQGDPQNATRQQ 960
+ E+ +P+ +T ++
Sbjct: 1382 PDGAKSQEKEEPEISTEKE 1400
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 19/85 (22%)
Query: 902 VNPMETYEDQHSSEEEEEEEEEEESEDG-------------EEEDDITSAESESS----- 943
+ P E E++ EEEEEEEE EE E G E+E+ S E E S
Sbjct: 1348 IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407
Query: 944 -EEEEGEQGDPQNATRQQQLEWDDS 967
EEEE E +P + + DDS
Sbjct: 1408 HEEEEEEDEEPSHNEDHDADDEDDS 1432
Score = 34.7 bits (78), Expect = 0.45
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 881 RDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAES 940
+D D K E + + ++ +D EEE+EE E D ++EDD +
Sbjct: 1380 KDPDGAKSQEKE--EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA 1437
Query: 941 ESSEEE 946
E +EE
Sbjct: 1438 EVEKEE 1443
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 882 DQDTGKENEMDWDDSALTITVNPMETYEDQHSS-----EEEEEEEEEEESEDGEEEDDIT 936
+++ G E D D + P + E + S+ EEEEEE+EE + + DD
Sbjct: 1371 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1430
Query: 937 SAESESSEEEEGE 949
+ ES+E E+ E
Sbjct: 1431 DSHMESAEVEKEE 1443
Score = 31.6 bits (70), Expect = 3.8
Identities = 13/45 (28%), Positives = 24/45 (53%)
Query: 919 EEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLE 963
E +E E+ EEED+ E E EE+E E+ + + ++ ++
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
Score = 31.2 bits (69), Expect = 4.9
Identities = 17/61 (27%), Positives = 29/61 (47%)
Query: 909 EDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDST 968
ED ++ EEEEEE+E E+ D + E E E+ + + ++ LE ++
Sbjct: 1400 EDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETF 1459
Query: 969 L 969
L
Sbjct: 1460 L 1460
>gi|11276081 protocadherin beta 8 precursor [Homo sapiens]
Length = 801
Score = 54.3 bits (129), Expect = 5e-07
Identities = 60/217 (27%), Positives = 85/217 (39%), Gaps = 33/217 (15%)
Query: 42 YHGIVTENDNTVLLDPPL--IALDKDAPLRFA--------------GEICGFKIHGQNVP 85
Y +V NDN P + + +D+P+ F GEI +
Sbjct: 230 YIEVVDVNDNAPEFQQPFYRVQISEDSPISFLVVKVSATDVDTGVNGEISYSLFQASDEI 289
Query: 86 FDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVN 145
VD TGE IR K++LD E + Y I+A D G S K TV IQV
Sbjct: 290 SKTFKVDFLTGE--IRLKKQLDFEKFQSYEVNIEARDAGGF--------SGKCTVLIQVI 339
Query: 146 DVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDK 205
DVN++AP ++ + + E + D D CS I D+PF +
Sbjct: 340 DVNDHAPEVTMSAFTSPIPENAPETVVALFSVSDLDSGENGKISCS---IQEDLPFLLKS 396
Query: 206 ---DGYIKNTE-KLNYGKEHQYKLTVTAYDCGKKRAT 238
+ Y TE L+ +Y +T+T D G R T
Sbjct: 397 SVGNFYTLLTETPLDRESRAEYNVTITVTDLGTPRLT 433
Score = 47.0 bits (110), Expect = 9e-05
Identities = 38/144 (26%), Positives = 66/144 (45%), Gaps = 10/144 (6%)
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE 165
LD E + + T+ A D G P +S A V+I+V DVN+ AP F++ Y+ + E
Sbjct: 201 LDREEEAELRLTLTALDGGSPP------RSGTAQVYIEVVDVNDNAPEFQQPFYRVQISE 254
Query: 166 GKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKD---GYIKNTEKLNYGKEH 221
+++V A D D S + ++ T D G I+ ++L++ K
Sbjct: 255 DSPISFLVVKVSATDVDTGVNGEISYSLFQASDEISKTFKVDFLTGEIRLKKQLDFEKFQ 314
Query: 222 QYKLTVTAYDCGKKRATEDVLVKI 245
Y++ + A D G VL+++
Sbjct: 315 SYEVNIEARDAGGFSGKCTVLIQV 338
Score = 39.3 bits (90), Expect = 0.018
Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 17/151 (11%)
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE 165
LD E + +Y+ TI D G T++ + + V+DVN+ AP F + SY V E
Sbjct: 410 LDRESRAEYNVTITVTDLGTPRLTTHLNMT------VLVSDVNDNAPAFTQTSYTLFVRE 463
Query: 166 GKQYD-SILRVEAVDADCSPQFSQICSYEIITPDVP-------FTVDKD-GYIKNTEKLN 216
I V A D D S +Q+ +Y ++ P P +++ D G++ L+
Sbjct: 464 NNSPALHIGSVSATDRD-SGTNAQV-TYSLLPPQDPHLPLASLVSINTDNGHLFALRSLD 521
Query: 217 YGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
Y ++ V A D G + + LV++ +
Sbjct: 522 YEALQAFEFRVGASDRGSPALSSEALVRVLV 552
>gi|9256604 protocadherin beta 11 precursor [Homo sapiens]
Length = 797
Score = 53.9 bits (128), Expect = 7e-07
Identities = 58/210 (27%), Positives = 89/210 (42%), Gaps = 18/210 (8%)
Query: 31 VNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVV 90
+N + P E ++ + +N++L LI D GEIC H
Sbjct: 235 INDNSPEFEQAFYEVKIR-ENSILGSLILIVSAWDLDSGTNGEICYTFSHASEDIRKTFE 293
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+++ +GE +R+ LD E + YS IQA D G G G K+TV I V DVN+
Sbjct: 294 INQKSGEITLRAP--LDFETIESYSIIIQATD-GGGLFG-------KSTVIIHVIDVNDN 343
Query: 151 APVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVD---KDG 207
AP S + + E ++ D D +CS I D+PF + ++
Sbjct: 344 APEITVSSITSPIPENTPETVVMVFSIQDIDSGDNGRIVCS---IPEDLPFVLKSSVENY 400
Query: 208 YIKNTEK-LNYGKEHQYKLTVTAYDCGKKR 236
Y TE+ L+ +Y +T+T D G R
Sbjct: 401 YTLETERPLDRESTAEYNITITVTDLGIPR 430
Score = 43.9 bits (102), Expect = 7e-04
Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 21/177 (11%)
Query: 83 NVPFDAVVVDKSTGEG--VIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATV 140
++P D V KS+ E + ++ LD E +Y+ TI D G +K H TV
Sbjct: 384 SIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGI----PRLKTEHNTTV 439
Query: 141 HIQVNDVNEYAPVFKEKSYKATVIEGKQYD-SILRVEAVDADCSPQFSQICSYEIITPD- 198
V+DVN+ AP F + SY V E I V A D D S +Q+ +Y ++ P
Sbjct: 440 --LVSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRD-SGTNAQV-NYSLLPPQD 495
Query: 199 --------VPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
V D +G++ L+Y + V A D G + + LV++ +
Sbjct: 496 LHLPLASLVSINTD-NGHLFALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLV 551
Score = 40.8 bits (94), Expect = 0.006
Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 10/144 (6%)
Query: 106 LDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIE 165
LD E + SF + A D G P +S A V + V D+N+ +P F++ Y+ + E
Sbjct: 200 LDYEELPELSFILSALDGGSPP------RSGTALVRVVVVDINDNSPEFEQAFYEVKIRE 253
Query: 166 GKQYDS-ILRVEAVDADCSPQFSQICSYEIITPDVPFTVD---KDGYIKNTEKLNYGKEH 221
S IL V A D D ++ + D+ T + K G I L++
Sbjct: 254 NSILGSLILIVSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIE 313
Query: 222 QYKLTVTAYDCGKKRATEDVLVKI 245
Y + + A D G V++ +
Sbjct: 314 SYSIIIQATDGGGLFGKSTVIIHV 337
Score = 32.3 bits (72), Expect = 2.2
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +QV D+N+++P+F EK + E ++ +E+ D + + SY I+P+
Sbjct: 119 IELQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESA-KDLDVGINAVKSY-TISPNS 176
Query: 200 PFTVDKDGYIKNTEK---------LNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
F + K I + K L+Y + + ++A D G + LV++ +
Sbjct: 177 HFHI-KMRVIPDNRKYPELVLDKALDYEELPELSFILSALDGGSPPRSGTALVRVVV 232
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 53.1 bits (126), Expect = 1e-06
Identities = 27/62 (43%), Positives = 36/62 (58%)
Query: 909 EDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDST 968
ED+ EEEEEEEE+EE E+ EEE++ E E EEEE E+ + + A + D S
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319
Query: 969 LS 970
S
Sbjct: 320 TS 321
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/274 (24%), Positives = 107/274 (39%), Gaps = 57/274 (20%)
Query: 685 EGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSE 744
+ DG+ED V+++ VS+E L+ E G++ H E+ E R K S+
Sbjct: 90 DSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAE---GRSPVKSHFGSNPI 146
Query: 745 LGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIH 804
T + + +SY+ ++ A SLL N I+ E VE ++
Sbjct: 147 GSATASSKGSYSSYQGII---------ATSLL-----------NLGQIAEETLVEEDLGQ 186
Query: 805 TANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFM 864
A P P VH + + + P A V+ V
Sbjct: 187 AAKP---------GPGIVHLLQEAAEGAASEE--GEKGLFIQPEDAEEVVEVT------- 228
Query: 865 IILGVFRIRAAHRRTMRDQDTGKENEMDW--DDSALTITVNPMETYEDQHSSEEEEEEEE 922
T R QD ++ D ++S+ + E +++ EEEEEEE+
Sbjct: 229 --------------TERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEED 274
Query: 923 EEESEDGEEEDDITSAESESSEEEEGEQGDPQNA 956
EEE E+ EEE++ E E EEEE E+ + + A
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 51.6 bits (122), Expect = 4e-06
Identities = 24/48 (50%), Positives = 31/48 (64%)
Query: 906 ETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDP 953
E E++ EEE+EEEEEEE E+ EEE++ E E EEEE E+ P
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 50.8 bits (120), Expect = 6e-06
Identities = 22/50 (44%), Positives = 32/50 (64%)
Query: 912 HSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQ 961
H E+EEEEEEEEE E+ EEE++ E E EEEE E+ + + +++
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 50.4 bits (119), Expect = 8e-06
Identities = 23/62 (37%), Positives = 37/62 (59%)
Query: 907 TYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDD 966
++E++ EEEEEEEEEE+ E+ EEE++ E E EEEE E+ + + + + +
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315
Query: 967 ST 968
T
Sbjct: 316 DT 317
Score = 37.7 bits (86), Expect = 0.053
Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 906 ETYEDQHSSEEEEEE----EEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQ 961
++ ED S E +++ EEE+ E+ EEE++ E E EEEE E+ + + +++
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 962 LEWDD 966
E ++
Sbjct: 298 EEEEE 302
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/171 (29%), Positives = 74/171 (43%), Gaps = 22/171 (12%)
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHK----------A 138
+V D+ T EGVI+ K+ LD E +K Y+F ++A +N+ H+ A
Sbjct: 319 IVTDEDTQEGVIKLKKPLDFETKKAYTFKVEA---------SNLHLDHRFHSAGPFKDTA 369
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSIL-RVEAVDADCSPQFSQICSYEIITP 197
TV I V DV+E PVF + Y V E +I+ V A D D +
Sbjct: 370 TVKISVLDVDE-PPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDG 428
Query: 198 DVPFTVD-KDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISI 247
D FT+D +G I E L+ QY ++ A T V + I++
Sbjct: 429 DSYFTIDGNEGTIATNELLDRESTAQYNFSIIASKVSNPLLTSKVNILINV 479
Score = 43.9 bits (102), Expect = 7e-04
Identities = 43/148 (29%), Positives = 69/148 (46%), Gaps = 13/148 (8%)
Query: 91 VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEY 150
+D++TG+ I + LD E + Y+ QA D T ++ I+V D+N+
Sbjct: 104 IDETTGD--IHAIRSLDREEKPFYTLRAQAVDIE-----TRKPLEPESEFIIKVQDINDN 156
Query: 151 APVFKEKSYKATVIEGKQYDS-ILRVEAVDADCSPQF--SQICSYEIITPDVPFTVDKDG 207
P F + Y ATV E + +L+V+A DAD P + S Y I+ F++D
Sbjct: 157 EPKFLDGPYVATVPEMSPVGAYVLQVKATDAD-DPTYGNSARVVYSILQGQPYFSIDPKT 215
Query: 208 YIKNTEKLNYGKE--HQYKLTVTAYDCG 233
+ T N +E QY++ + A D G
Sbjct: 216 GVIRTALPNMDREVKEQYQVLIQAKDMG 243
Score = 37.7 bits (86), Expect = 0.053
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 11/95 (11%)
Query: 97 EGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKE 156
EG I + E LD E Y+F+I A +N + K + I V DVNE+ P
Sbjct: 438 EGTIATNELLDRESTAQYNFSIIASKV------SNPLLTSKVNILINVLDVNEFPPEI-S 490
Query: 157 KSYKATVIEGKQYDSILR-VEAVDADCSP---QFS 187
Y+ V E + I++ V A D D SP QFS
Sbjct: 491 VPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFS 525
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
Length = 1955
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1087 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1146
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1147 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1199
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 446
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 447 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 493
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 494 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 537
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 660 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 712
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 770
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 771 IYTAVKLNREVRDYYELVVVATD 793
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 702 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 761
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 762 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 813
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 814 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 861
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 379 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 438
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 439 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 496
Query: 245 ISI 247
I +
Sbjct: 497 IQV 499
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 193 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 236
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
Length = 1932
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1065 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1124
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1125 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1177
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 367 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 424
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 425 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 471
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 472 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 515
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 871 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 923
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 984 VVAFDDGEPVMSSSATVKILV 1004
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 638 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 690
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 691 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 748
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 749 IYTAVKLNREVRDYYELVVVATD 771
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 680 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 739
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 740 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 791
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 792 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 839
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 357 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 416
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 417 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 474
Query: 245 ISI 247
I +
Sbjct: 475 IQV 477
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 170
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 171 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 214
>gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapiens]
Length = 1677
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1087 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1146
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1147 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1199
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 446
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 447 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 493
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 494 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 537
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 660 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 712
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 770
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 771 IYTAVKLNREVRDYYELVVVATD 793
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 702 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 761
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 762 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 813
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 814 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 861
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 379 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 438
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 439 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 496
Query: 245 ISI 247
I +
Sbjct: 497 IQV 499
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 193 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 236
>gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapiens]
Length = 1682
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1092 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1151
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1152 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1204
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 394 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 451
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 452 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 498
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 499 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 542
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 898 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 950
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 1011 VVAFDDGEPVMSSSATVKILV 1031
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 665 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 717
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 718 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 775
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 776 IYTAVKLNREVRDYYELVVVATD 798
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 707 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 766
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 767 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 818
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 819 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 866
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 384 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 443
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 444 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 501
Query: 245 ISI 247
I +
Sbjct: 502 IQV 504
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 198 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 241
>gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapiens]
Length = 1539
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1087 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1146
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1147 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1199
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 446
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 447 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 493
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 494 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 537
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 660 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 712
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 770
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 771 IYTAVKLNREVRDYYELVVVATD 793
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 702 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 761
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 762 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 813
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 814 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 861
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 379 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 438
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 439 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 496
Query: 245 ISI 247
I +
Sbjct: 497 IQV 499
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 193 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 236
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1099 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1158
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1159 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1211
Score = 47.0 bits (110), Expect = 9e-05
Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 9/79 (11%)
Query: 104 EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATV 163
+ +D E Q+ Y+F+I A+D V++S V+IQV D N+ P F E SY V
Sbjct: 479 QPVDREEQQTYTFSITAFD--------GVQESEPVIVNIQVMDANDNTPTFPEISYDVYV 530
Query: 164 -IEGKQYDSILRVEAVDAD 181
+ + DS++++ AVDAD
Sbjct: 531 YTDMRPGDSVIQLTAVDAD 549
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 905 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 957
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 958 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1017
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 1018 VVAFDDGEPVMSSSATVKILV 1038
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 672 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 724
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 725 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 782
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 783 IYTAVKLNREVRDYYELVVVATD 805
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 714 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 773
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 774 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 825
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 826 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 873
Score = 38.9 bits (89), Expect = 0.024
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 882 DQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESE 941
DQ+ E+ ++ ++ + + + E E++ E E EEE ESE EE++ ++ ESE
Sbjct: 1592 DQEEATESTVESEEESSS---DYTEYSEEESEFSESETTEEESESETPSEEEESSTPESE 1648
Query: 942 SSEEEEGE 949
SE E E
Sbjct: 1649 ESESTESE 1656
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 909 EDQHSSEEEEEEEEEEESEDGEEED--DITSAESESSE-----EEEGEQGDPQNATRQQ 960
E++HS EEE EES D E +D + SAES S E EEE E G +++ Q
Sbjct: 1697 EEEHSEEEESGPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGSSSSSSESQ 1755
Score = 35.4 bits (80), Expect = 0.26
Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 894 DDSALTITVNPMETYEDQHSSEEEEE----EEEEEESEDGEEEDDITSAESESSEEEEGE 949
D L +T++ E E SEEE E EEESE E E +ESE+ EEE E
Sbjct: 1583 DKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEE-E 1641
Query: 950 QGDPQN 955
P++
Sbjct: 1642 SSTPES 1647
Score = 33.9 bits (76), Expect = 0.76
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 891 MDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESS--EEEEG 948
+D +++ + + E+ D EEE E E E+ + E E + S E ESS E EE
Sbjct: 1591 LDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPESEES 1650
Query: 949 EQGDPQNATRQQQL 962
E + + ++ +
Sbjct: 1651 ESTESEGEKARKNI 1664
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 198 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 241
Score = 31.6 bits (70), Expect = 3.8
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 30/134 (22%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 384 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD----IE 439
Query: 188 QICSYEIITPDVP-----------FTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCG 233
+ + T D FTV + G Y+ + ++ ++ Y ++TA+D
Sbjct: 440 DVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD-- 497
Query: 234 KKRATEDVLVKISI 247
+ +E V+V I +
Sbjct: 498 GVQESEPVIVNIQV 511
Score = 31.2 bits (69), Expect = 4.9
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 907 TYEDQHSSEEEEEEEEEEESEDGE-EEDDITSAESESSEEE-EGEQGDPQNATRQQQLEW 964
T + + ++E E EEE S+ E E++ +ESE++EEE E E + + + E
Sbjct: 1590 TLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPESEE 1649
Query: 965 DDSTLS 970
+ST S
Sbjct: 1650 SESTES 1655
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
Length = 1935
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1065 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1124
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1125 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1177
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 367 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 424
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 425 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 471
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 472 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 515
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 871 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 923
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 984 VVAFDDGEPVMSSSATVKILV 1004
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 638 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 690
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 691 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 748
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 749 IYTAVKLNREVRDYYELVVVATD 771
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 680 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 739
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 740 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 791
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 792 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 839
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 357 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 416
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 417 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 474
Query: 245 ISI 247
I +
Sbjct: 475 IQV 477
Score = 32.3 bits (72), Expect = 2.2
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 18/107 (16%)
Query: 140 VHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRV------EAVDADCSP--QFSQICS 191
V I V D N+ +P FK +SY ATV E + + A D D P Q +
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 170
Query: 192 YEIITPDVPFTVDK-------DGYIKNTEKLNYGKEHQYKLTVTAYD 231
Y PD P + D G I ++LNY + +Y + + A D
Sbjct: 171 Y---NPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 214
>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
Length = 1915
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 98 GVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNV-KKSHKATVHIQVNDVNEYAPVFKE 156
GVI LD E + Y +QA V KS+ A V+I++ D N + PVF++
Sbjct: 1050 GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1109
Query: 157 KSYKATVIE-GKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNT 212
K Y V E + + S+LRV+A D D + +Y +I P P K+G++ T
Sbjct: 1110 KFYIGGVSEDARMFTSVLRVKATDKDTGNY--SVMAYRLIIP--PIKEGKEGFVVET 1162
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 29/164 (17%)
Query: 32 NKHKPWLE-PTYHGIVTEN--------DNTVLLDP-PLIALDKDAPLRFAGEICGFKIHG 81
N P+ P+Y G + E+ D+ L P ++ALDKD E+ F
Sbjct: 352 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLN-- 409
Query: 82 QNVPFDAVVVDKSTGEGVIRSK---EKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKA 138
D V T G+ R + +D E Q+ Y+F+I A+D V++S
Sbjct: 410 -----DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPV 456
Query: 139 TVHIQVNDVNEYAPVFKEKSYKATV-IEGKQYDSILRVEAVDAD 181
V+IQV D N+ P F E SY V + + DS++++ AVDAD
Sbjct: 457 IVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 500
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 115 SFTIQAYDC-GKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVI-EGKQYDSI 172
+F ++A+D G P G ATV + V D+N+Y PVF ++ YK V + + I
Sbjct: 856 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 908
Query: 173 LRVEAVDADCSPQFSQICSYEIITPDVP-----FTVDKD-GYIKNTEKLNYGKEHQYKLT 226
V A DAD + Y + P F V++D G + LN +KL
Sbjct: 909 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 968
Query: 227 VTAYDCGKKRATEDVLVKISI 247
V A+D G+ + VKI +
Sbjct: 969 VVAFDDGEPVMSSSATVKILV 989
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 90 VVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNE 149
V + S G++ + LD E Y I A D G+ PDGT+ ATV+I V DVN+
Sbjct: 623 VFNLSETTGILTLGKALDRESTDRYILIITASD-GR-PDGTST-----ATVNIVVTDVND 675
Query: 150 YAPVFKE-KSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGY 208
APVF +V+E + + +V+A D D + Y + + F + +G
Sbjct: 676 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNLFRITSNGS 733
Query: 209 IKNTEKLNYGKEHQYKLTVTAYD 231
I KLN Y+L V A D
Sbjct: 734 IYTAVKLNREVRDYYELVVVATD 756
Score = 40.0 bits (92), Expect = 0.011
Identities = 44/172 (25%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 41 TYHGIVTE-NDNTVLLDPPL---IALDKDAPLRFAGEI--------CGFKIHGQNVPFDA 88
T + +VT+ NDN + DP L +++ ++ F G++ ++H F+
Sbjct: 665 TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNN 724
Query: 89 VVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVN 148
+ + T G I + KL+ E++ Y + A D P + + T+ I+V D++
Sbjct: 725 LF--RITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTL------TLAIKVLDID 776
Query: 149 EYAPVFKEKSYKATVIEG-KQYDSILRVEAVDADCSPQFSQICSYEIITPDV 199
+ +PVF +Y V E +IL++EA D D SY I +P+V
Sbjct: 777 DNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEV 824
Score = 35.0 bits (79), Expect = 0.34
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 138 ATVHIQVNDVNEYAPVFKEKSYK----------ATVIEGKQYDSILRVEAVDADCSPQFS 187
A +HI++ D N +P F SY+ AT+ + S LR+ A+D D
Sbjct: 342 AGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKD 401
Query: 188 QICSYEIITPDVPFTVDKDG---YIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 244
+ FTV + G Y+ + ++ ++ Y ++TA+D + +E V+V
Sbjct: 402 PELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVN 459
Query: 245 ISI 247
I +
Sbjct: 460 IQV 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,391,982
Number of Sequences: 37866
Number of extensions: 2016606
Number of successful extensions: 38930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 690
Number of HSP's successfully gapped in prelim test: 319
Number of HSP's that attempted gapping in prelim test: 16234
Number of HSP's gapped (non-prelim): 11482
length of query: 971
length of database: 18,247,518
effective HSP length: 112
effective length of query: 859
effective length of database: 14,006,526
effective search space: 12031605834
effective search space used: 12031605834
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.