Guide to the Human Genome
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Search of human proteins with 56699482

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
         (518 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56699482 hypothetical protein LOC25940 [Homo sapiens]             1084   0.0  
gi|109452587 family with sequence similarity 98, member B isofor...   447   e-125
gi|109452589 family with sequence similarity 98, member B isofor...   303   3e-82
gi|116812620 hypothetical protein LOC147965 [Homo sapiens]            221   2e-57
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]          112   6e-25
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]         112   6e-25
gi|55956899 keratin 9 [Homo sapiens]                                  110   4e-24
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...   105   1e-22
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...   104   2e-22
gi|195972866 keratin 10 [Homo sapiens]                                 95   2e-19
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    91   3e-18
gi|109255251 loricrin [Homo sapiens]                                   86   1e-16
gi|119395750 keratin 1 [Homo sapiens]                                  85   1e-16
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    83   5e-16
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    83   5e-16
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    82   2e-15
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    82   2e-15
gi|57864582 hornerin [Homo sapiens]                                    81   3e-15
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ...    80   3e-15
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    80   6e-15
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    79   8e-15
gi|47132620 keratin 2 [Homo sapiens]                                   79   1e-14
gi|62122917 filaggrin family member 2 [Homo sapiens]                   78   2e-14
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom...    75   1e-13
gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Hom...    75   1e-13
gi|109148552 keratin 3 [Homo sapiens]                                  72   9e-13
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...    72   1e-12
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    72   2e-12
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    72   2e-12
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    72   2e-12

>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 518/518 (100%), Positives = 518/518 (100%)

Query: 1   MECDLMETDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLE 60
           MECDLMETDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLE
Sbjct: 1   MECDLMETDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLE 60

Query: 61  ENVQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELE 120
           ENVQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELE
Sbjct: 61  ENVQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELE 120

Query: 121 AARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLA 180
           AARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLA
Sbjct: 121 AARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLA 180

Query: 181 KVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAK 240
           KVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAK
Sbjct: 181 KVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAK 240

Query: 241 SQTEKLAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMG 300
           SQTEKLAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMG
Sbjct: 241 SQTEKLAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMG 300

Query: 301 RVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGR 360
           RVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGR
Sbjct: 301 RVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGR 360

Query: 361 GGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420
           GGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG
Sbjct: 361 GGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420

Query: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480
           GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW
Sbjct: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480

Query: 481 GGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS 518
           GGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS
Sbjct: 481 GGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS 518


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score =  447 bits (1149), Expect = e-125
 Identities = 247/464 (53%), Positives = 308/464 (66%), Gaps = 46/464 (9%)

Query: 6   METDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEENVQA 65
           ME D+L++LE LGYKGPLLE+ AL++A   G SSPEF++LC WL S+++ LC LEE++ +
Sbjct: 12  MEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITS 71

Query: 66  TNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAARML 125
                + E FQLE+SG L EM CPY  L SGD+  RL  +++CL LL +L +EL+A+++L
Sbjct: 72  AGR-DDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQASQIL 130

Query: 126 CVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPN 185
             N   K +Q    SEV+QE++ +   LG+ K   +  +    + +E K+K+ L+KV  N
Sbjct: 131 -QNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTS-DIPHMLNQVESKVKDILSKVQKN 188

Query: 186 HVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTEK 245
           HVGKPLLK  +     E++E IN A++ EYE RR++L+KRLDVTVQSFGWSDRAK +T+ 
Sbjct: 189 HVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSDRAKVKTDD 248

Query: 246 LAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMGRVPDR 305
           +A++YQPKR  LSPKTTI++AHLLAAR+DLSKI+RTSSG+ REKTACAINKVLMGRVPDR
Sbjct: 249 IARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKVLMGRVPDR 308

Query: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
           GGRPNEIEPPPPEMPPWQKRQ+G     GGRGG  GG      GG GG   GGG GGRGG
Sbjct: 309 GGRPNEIEPPPPEMPPWQKRQEG----GGGRGGWGGG------GGGGGRGGGGGGGGRGG 358

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425
           +  GG G G G    GGW  GG GG G          GFQ  G +GG        GGYGG
Sbjct: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRG----------GFQGRGDYGGR-------GGYGG 401

Query: 426 FQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
                     GY G GY        G  +G  GGG GG GG GG
Sbjct: 402 --------RGGYGGRGY--------GDPYGGGGGGGGGGGGGGG 429



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 39/106 (36%), Positives = 45/106 (42%), Gaps = 22/106 (20%)

Query: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGR 470
           GG   GG+ GGG GG        G G  GGG             G RGG  GG GG GG 
Sbjct: 331 GGGGRGGWGGGGGGG--------GRGGGGGG-------------GGRGGWGGGGGGWGGG 369

Query: 471 GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHY 516
           GG  G  GG GG G   +   G +     +GG +  + G G G  Y
Sbjct: 370 GGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGG-RGGYGGRGYGDPY 414



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 26/50 (52%), Positives = 28/50 (56%)

Query: 443 QQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGG 492
           Q+    + G   G  GGGRGG GG GGRGG  G GGGWGG G      GG
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378


>gi|109452589 family with sequence similarity 98, member B isoform 2
           [Homo sapiens]
          Length = 330

 Score =  303 bits (775), Expect = 3e-82
 Identities = 158/292 (54%), Positives = 215/292 (73%), Gaps = 3/292 (1%)

Query: 6   METDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEENVQA 65
           ME D+L++LE LGYKGPLLE+ AL++A   G SSPEF++LC WL S+++ LC LEE++ +
Sbjct: 12  MEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITS 71

Query: 66  TNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAARML 125
                + E FQLE+SG L EM CPY  L SGD+  RL  +++CL LL +L +EL+A+++L
Sbjct: 72  AGR-DDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQASQIL 130

Query: 126 CVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPN 185
             N   K +Q    SEV+QE++ +   LG+ K   +  +    + +E K+K+ L+KV  N
Sbjct: 131 -QNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTS-DIPHMLNQVESKVKDILSKVQKN 188

Query: 186 HVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTEK 245
           HVGKPLLK  +     E++E IN A++ EYE RR++L+KRLDVTVQSFGWSDRAK +T+ 
Sbjct: 189 HVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSDRAKVKTDD 248

Query: 246 LAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKV 297
           +A++YQPKR  LSPKTTI++AHLLAAR+DLSKI+RTSSG+ REKTACAINKV
Sbjct: 249 IARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV 300


>gi|116812620 hypothetical protein LOC147965 [Homo sapiens]
          Length = 349

 Score =  221 bits (562), Expect = 2e-57
 Identities = 133/341 (39%), Positives = 190/341 (55%), Gaps = 25/341 (7%)

Query: 10  ILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEEN------- 62
           + + L  LGY       G +  A S GAS P+F  LC  L +EL  L  LE+        
Sbjct: 14  VAQDLLALGY-------GGVPGAASRGASCPDFRGLCVRLAAELATLGALEQQREAGAEV 66

Query: 63  VQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAA 122
           + A + P   E+F  ++  LL E++CP  +L  GD    L      L LL +L SEL+A 
Sbjct: 67  LSAGDGPGAEEDFLRQLGSLLRELHCPDRALCGGDGAAALREPGAGLRLLRFLCSELQAT 126

Query: 123 RMLCVNA-------PPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKL 175
           R+LC+ +       PP       G+ + QEL     ALG+ +P       Q    +  K+
Sbjct: 127 RLLCLRSLLDPSPRPPLGEGVVEGAGMVQELDLTLQALGLPRPAPGTPASQLLQELHAKI 186

Query: 176 KETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGW 235
            E    +PP  + +PLL   +    WE +E+++Q++ ++Y  RR LL+KRLD+T  +F W
Sbjct: 187 SELQPSLPPGSL-QPLLSCSLDAPRWEALESLSQSLRDQYRCRRCLLLKRLDLTTSAFHW 245

Query: 236 SDRAKSQTEKLAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAIN 295
           SDRA++Q E +  V  P R VL+P++ IS+AH+LAAR DLS ++  +S ++R  T CAIN
Sbjct: 246 SDRAEAQGEAMRAVLIPIREVLTPESDISIAHVLAARADLSCLVPATSVAVRRGTCCAIN 305

Query: 296 KVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGR 336
           KVLMG VPDRGGRPNE+EPP   MP W+ R++    Q  GR
Sbjct: 306 KVLMGNVPDRGGRPNELEPP---MPTWRSRREDGGPQCWGR 343


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score =  112 bits (281), Expect = 6e-25
 Identities = 81/183 (44%), Positives = 90/183 (49%), Gaps = 22/183 (12%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG-G 392
           GGRGG RGGY     G R G   GG R   GGY     GGG G    GG   G  GGG G
Sbjct: 406 GGRGGDRGGYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 461

Query: 393 GYQDGGY-RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
           G + GGY  D G   GG  GG+  GG +GGGYGG        G G   GGY  D     G
Sbjct: 462 GDRGGGYGGDRGGGYGGDRGGY--GGDRGGGYGG-----DRGGYGGDRGGYGGDR----G 510

Query: 452 GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNY---HQGGQFEQHFQHGGYQYNHS 508
           G+ GDR GG GG   RGG GG  G G G+GG  S  Y     GG +    + GGY  +  
Sbjct: 511 GYGGDR-GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD-RGGGYGGDRG 568

Query: 509 GFG 511
           G+G
Sbjct: 569 GYG 571



 Score =  105 bits (261), Expect = 1e-22
 Identities = 90/223 (40%), Positives = 103/223 (46%), Gaps = 59/223 (26%)

Query: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369
           N+   P PE            + +GG   GRG      YGG  G+    GRGGRGG D G
Sbjct: 374 NQCNEPRPE----------DSRPSGGDFRGRG------YGGERGYR---GRGGRGG-DRG 413

Query: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGY---QGGGYGGF 426
           G GG R     GG   G    GGGY   G R  G    GY G  S GGY   +GGGYGG 
Sbjct: 414 GYGGDRS----GGGYGGDRSSGGGYS--GDRSGG----GYGGDRSGGGYGGDRGGGYGGD 463

Query: 427 QTSSSYTGSGY---QGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG--------RGGRA 474
           +      G GY   +GGGY  D     GG+ GDRGGG GG RGG GG        RGG  
Sbjct: 464 R------GGGYGGDRGGGYGGDR----GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 513

Query: 475 GQGGGWGGRGSQNYH----QGGQFEQHFQHGGYQYNHSGFGQG 513
           G  GG+GG  S+  +     GG      + GGY  + SG G G
Sbjct: 514 GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 556



 Score =  101 bits (251), Expect = 2e-21
 Identities = 76/166 (45%), Positives = 84/166 (50%), Gaps = 33/166 (19%)

Query: 352 GGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYH 410
           GG  +G G GG  GY   GGRGG RG         GG   GGGY  GG R SG   GGY 
Sbjct: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGY-------GGDRSGGGY--GGDRSSG---GGYS 435

Query: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG 469
           G  S     GGGYGG ++   Y G   +GGGY  D   + GG+ GDRGGG GG RGG GG
Sbjct: 436 GDRS-----GGGYGGDRSGGGYGGD--RGGGYGGD---RGGGYGGDRGGGYGGDRGGYGG 485

Query: 470 -RGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
            RGG  G GG  GG G      GG        GGY  +  G+G  R
Sbjct: 486 DRGG--GYGGDRGGYGGDRGGYGGD------RGGYGGDRGGYGGDR 523



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 69/147 (46%), Positives = 73/147 (49%), Gaps = 30/147 (20%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK--HQGGWTDGGSGGG 391
           G RGGG GG     YGG  G   GG RGG GG   GG GG RG     +GG+  GG  GG
Sbjct: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY--GGDRGG 511

Query: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---GGYQQDNRY 448
            G   GGY           GG  S G  GG  GG        GSGY G   GGY  D   
Sbjct: 512 YGGDRGGY-----------GGDRSRGGYGGDRGG--------GSGYGGDRSGGYGGDR-- 550

Query: 449 QDGGHHGDRGGGRGG-RGGRGGR-GGR 473
             GG+ GDRGGG GG RGG GG+ GGR
Sbjct: 551 SGGGYGGDRGGGYGGDRGGYGGKMGGR 577



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 71/260 (27%), Positives = 86/260 (33%), Gaps = 76/260 (29%)

Query: 326 QDGPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGG------- 374
           +DG    TG  GG RGG++    H  YG R   +              G G G       
Sbjct: 189 KDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVG 248

Query: 375 ---------RGNKHQGG-----WTDGGSGGGGGYQDGGYRD------------------- 401
                    + NK  G      +TD  +G   G     + D                   
Sbjct: 249 EFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGN 308

Query: 402 ------SGFQPGGYHGGHSSGGYQG-GGY---GGFQTSSSYTGSG--------------Y 437
                 +  +P    GG S GG +G GGY   GGFQ       SG               
Sbjct: 309 IIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFA 368

Query: 438 QGGGYQQDN--RYQDGGHHGD--RGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
           +     Q N  R +D    G   RG G GG  G  GRGGR G  GG+GG  S     GG 
Sbjct: 369 RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS----GGGY 424

Query: 494 FEQHFQHGGYQYNHSGFGQG 513
                  GGY  + SG G G
Sbjct: 425 GGDRSSGGGYSGDRSGGGYG 444



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 33/74 (44%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 334 GGRGGGRGGY----EHSSYGGR--GGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
           GG GG RGGY        YGG   GG   GG R   GGY     GGG G    GG+  GG
Sbjct: 510 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGGDRSGGGYGGDRGGGY--GG 565

Query: 388 SGGGGGYQDGGYRD 401
             GG G + GG  D
Sbjct: 566 DRGGYGGKMGGRND 579



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 28/61 (45%), Positives = 30/61 (49%), Gaps = 4/61 (6%)

Query: 328 GPQQQTGGRGGGRG---GYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
           G  +  GG GG RG   GY     GG GG   GGG GG  G  +GG  GG G K  GG  
Sbjct: 520 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGK-MGGRN 578

Query: 385 D 385
           D
Sbjct: 579 D 579



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/207 (28%), Positives = 76/207 (36%), Gaps = 50/207 (24%)

Query: 326 QDGPQQQT-------GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY--DHGGRGGGRG 376
           Q G +QQ+       G +G G+    +S YG       G    G   Y   +    GG  
Sbjct: 9   QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYE 68

Query: 377 NKHQGGWTDG------------GSGGGGG------YQDGGYRDSGFQPGGY--HGG---- 412
           N+ Q  ++               SG  GG        D G +DS  Q  GY  H G    
Sbjct: 69  NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 128

Query: 413 HSSGGYQGGGYGGFQTSSSYTGSGYQG---------GGYQQDNRYQDGGHHGDRGGGRGG 463
            S+   Q   Y   Q S       Y             Y +DNR    G+ G +GGGR G
Sbjct: 129 QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR----GYGGSQGGGR-G 183

Query: 464 RGG--RGGRGGRAGQGGGWGGRGSQNY 488
           RGG  + GRG   G  GG  G G +N+
Sbjct: 184 RGGYDKDGRGPMTGSSGGDRG-GFKNF 209



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 41/154 (26%), Positives = 54/154 (35%), Gaps = 28/154 (18%)

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---- 439
           +D GS G  G +   Y   G  PG    G +S  Y G G    QT+ S  G  Y G    
Sbjct: 2   SDSGSYGQSGGEQQSYSTYG-NPGSQGYGQASQSYSGYG----QTTDSSYGQNYSGYSSY 56

Query: 440 --------GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA--------GQGGGWGGR 483
                   GGY+   +        +  G +      G +GGRA        GQ   +  +
Sbjct: 57  GQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 116

Query: 484 GSQNYHQGGQFEQ---HFQHGGYQYNHSGFGQGR 514
              + HQG   EQ     QH  Y  N   +   R
Sbjct: 117 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR 150



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 35/173 (20%)

Query: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
           GG  N+ +    + P   + Q    + +G +GG    Y+   YG +  ++Q      + G
Sbjct: 65  GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ------QSG 118

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGH---------SSG 416
           YD          +HQG + D  S     +         +     +  H         S  
Sbjct: 119 YD----------QHQGSY-DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 167

Query: 417 GYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
           G    GYGG Q      G G   GGY +D R   G   G  GG RGG    GG
Sbjct: 168 GEDNRGYGGSQ------GGGRGRGGYDKDGR---GPMTGSSGGDRGGFKNFGG 211



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 318 EMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRG 376
           E   + ++ D   Q        R  Y H +   R    + G    G GG   GGRG G  
Sbjct: 128 EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGY 187

Query: 377 NKHQGGWTDGGSGGG-GGYQD-GGYRDSG 403
           +K   G   G SGG  GG+++ GG+RD G
Sbjct: 188 DKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGG-RGGHEQGGGRGGRGGYDHGGR 371
           G  +  GG GG RGG     YGG RGG+  GG  GGR  Y +  R
Sbjct: 547 GGDRSGGGYGGDRGG----GYGGDRGGY--GGKMGGRNDYRNDQR 585


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score =  112 bits (281), Expect = 6e-25
 Identities = 81/183 (44%), Positives = 90/183 (49%), Gaps = 22/183 (12%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG-G 392
           GGRGG RGGY     G R G   GG R   GGY     GGG G    GG   G  GGG G
Sbjct: 409 GGRGGDRGGYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 464

Query: 393 GYQDGGY-RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
           G + GGY  D G   GG  GG+  GG +GGGYGG        G G   GGY  D     G
Sbjct: 465 GDRGGGYGGDRGGGYGGDRGGY--GGDRGGGYGG-----DRGGYGGDRGGYGGDR----G 513

Query: 452 GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNY---HQGGQFEQHFQHGGYQYNHS 508
           G+ GDR GG GG   RGG GG  G G G+GG  S  Y     GG +    + GGY  +  
Sbjct: 514 GYGGDR-GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD-RGGGYGGDRG 571

Query: 509 GFG 511
           G+G
Sbjct: 572 GYG 574



 Score =  105 bits (261), Expect = 1e-22
 Identities = 90/223 (40%), Positives = 103/223 (46%), Gaps = 59/223 (26%)

Query: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369
           N+   P PE            + +GG   GRG      YGG  G+    GRGGRGG D G
Sbjct: 377 NQCNEPRPE----------DSRPSGGDFRGRG------YGGERGYR---GRGGRGG-DRG 416

Query: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGY---QGGGYGGF 426
           G GG R     GG   G    GGGY   G R  G    GY G  S GGY   +GGGYGG 
Sbjct: 417 GYGGDRS----GGGYGGDRSSGGGYS--GDRSGG----GYGGDRSGGGYGGDRGGGYGGD 466

Query: 427 QTSSSYTGSGY---QGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG--------RGGRA 474
           +      G GY   +GGGY  D     GG+ GDRGGG GG RGG GG        RGG  
Sbjct: 467 R------GGGYGGDRGGGYGGDR----GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 516

Query: 475 GQGGGWGGRGSQNYH----QGGQFEQHFQHGGYQYNHSGFGQG 513
           G  GG+GG  S+  +     GG      + GGY  + SG G G
Sbjct: 517 GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 559



 Score =  101 bits (251), Expect = 2e-21
 Identities = 76/166 (45%), Positives = 84/166 (50%), Gaps = 33/166 (19%)

Query: 352 GGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYH 410
           GG  +G G GG  GY   GGRGG RG         GG   GGGY  GG R SG   GGY 
Sbjct: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGY-------GGDRSGGGY--GGDRSSG---GGYS 438

Query: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG 469
           G  S     GGGYGG ++   Y G   +GGGY  D   + GG+ GDRGGG GG RGG GG
Sbjct: 439 GDRS-----GGGYGGDRSGGGYGGD--RGGGYGGD---RGGGYGGDRGGGYGGDRGGYGG 488

Query: 470 -RGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
            RGG  G GG  GG G      GG        GGY  +  G+G  R
Sbjct: 489 DRGG--GYGGDRGGYGGDRGGYGGD------RGGYGGDRGGYGGDR 526



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 69/147 (46%), Positives = 73/147 (49%), Gaps = 30/147 (20%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK--HQGGWTDGGSGGG 391
           G RGGG GG     YGG  G   GG RGG GG   GG GG RG     +GG+  GG  GG
Sbjct: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY--GGDRGG 514

Query: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---GGYQQDNRY 448
            G   GGY           GG  S G  GG  GG        GSGY G   GGY  D   
Sbjct: 515 YGGDRGGY-----------GGDRSRGGYGGDRGG--------GSGYGGDRSGGYGGDR-- 553

Query: 449 QDGGHHGDRGGGRGG-RGGRGGR-GGR 473
             GG+ GDRGGG GG RGG GG+ GGR
Sbjct: 554 SGGGYGGDRGGGYGGDRGGYGGKMGGR 580



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 71/260 (27%), Positives = 86/260 (33%), Gaps = 76/260 (29%)

Query: 326 QDGPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGG------- 374
           +DG    TG  GG RGG++    H  YG R   +              G G G       
Sbjct: 192 KDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVG 251

Query: 375 ---------RGNKHQGG-----WTDGGSGGGGGYQDGGYRD------------------- 401
                    + NK  G      +TD  +G   G     + D                   
Sbjct: 252 EFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGN 311

Query: 402 ------SGFQPGGYHGGHSSGGYQG-GGY---GGFQTSSSYTGSG--------------Y 437
                 +  +P    GG S GG +G GGY   GGFQ       SG               
Sbjct: 312 IIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFA 371

Query: 438 QGGGYQQDN--RYQDGGHHGD--RGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
           +     Q N  R +D    G   RG G GG  G  GRGGR G  GG+GG  S     GG 
Sbjct: 372 RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS----GGGY 427

Query: 494 FEQHFQHGGYQYNHSGFGQG 513
                  GGY  + SG G G
Sbjct: 428 GGDRSSGGGYSGDRSGGGYG 447



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 33/74 (44%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 334 GGRGGGRGGY----EHSSYGGR--GGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
           GG GG RGGY        YGG   GG   GG R   GGY     GGG G    GG+  GG
Sbjct: 513 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGGDRSGGGYGGDRGGGY--GG 568

Query: 388 SGGGGGYQDGGYRD 401
             GG G + GG  D
Sbjct: 569 DRGGYGGKMGGRND 582



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 28/61 (45%), Positives = 30/61 (49%), Gaps = 4/61 (6%)

Query: 328 GPQQQTGGRGGGRG---GYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
           G  +  GG GG RG   GY     GG GG   GGG GG  G  +GG  GG G K  GG  
Sbjct: 523 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGK-MGGRN 581

Query: 385 D 385
           D
Sbjct: 582 D 582



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 60/210 (28%), Positives = 76/210 (36%), Gaps = 53/210 (25%)

Query: 326 QDGPQQQT-------GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRG-----G 373
           Q G +QQ+       G +G G+    +S YG       G    G   Y     G     G
Sbjct: 9   QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYG 68

Query: 374 GRGNKHQGGWTDG------------GSGGGGG------YQDGGYRDSGFQPGGY--HGG- 412
           G  N+ Q  ++               SG  GG        D G +DS  Q  GY  H G 
Sbjct: 69  GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 128

Query: 413 ---HSSGGYQGGGYGGFQTSSSYTGSGYQG---------GGYQQDNRYQDGGHHGDRGGG 460
               S+   Q   Y   Q S       Y             Y +DNR    G+ G +GGG
Sbjct: 129 YDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR----GYGGSQGGG 184

Query: 461 RGGRGG--RGGRGGRAGQGGGWGGRGSQNY 488
           R GRGG  + GRG   G  GG  G G +N+
Sbjct: 185 R-GRGGYDKDGRGPMTGSSGGDRG-GFKNF 212



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 35/173 (20%)

Query: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
           GG  N+ +    + P   + Q    + +G +GG    Y+   YG +  ++Q      + G
Sbjct: 68  GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ------QSG 121

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGH---------SSG 416
           YD          +HQG + D  S     +         +     +  H         S  
Sbjct: 122 YD----------QHQGSY-DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 170

Query: 417 GYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
           G    GYGG Q      G G   GGY +D R   G   G  GG RGG    GG
Sbjct: 171 GEDNRGYGGSQ------GGGRGRGGYDKDGR---GPMTGSSGGDRGGFKNFGG 214



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 43/155 (27%), Positives = 56/155 (36%), Gaps = 27/155 (17%)

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGG------YGGFQTSSSYTGSGY 437
           +D GS G  G +   Y   G  PG    G +S  Y G G      YG  Q  S Y+  G 
Sbjct: 2   SDSGSYGQSGGEQQSYSTYG-NPGSQGYGQASQSYSGYGQTTDSSYG--QNYSGYSSYGQ 58

Query: 438 QGGGYQQ-----DNRYQDGGHHG--DRGGGRGGRGGRGGRGGRA--------GQGGGWGG 482
              GY Q     +N+ Q        +  G +      G +GGRA        GQ   +  
Sbjct: 59  SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 118

Query: 483 RGSQNYHQGGQFEQ---HFQHGGYQYNHSGFGQGR 514
           +   + HQG   EQ     QH  Y  N   +   R
Sbjct: 119 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR 153



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 318 EMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRG 376
           E   + ++ D   Q        R  Y H +   R    + G    G GG   GGRG G  
Sbjct: 131 EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGY 190

Query: 377 NKHQGGWTDGGSGGG-GGYQD-GGYRDSG 403
           +K   G   G SGG  GG+++ GG+RD G
Sbjct: 191 DKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGG-RGGHEQGGGRGGRGGYDHGGR 371
           G  +  GG GG RGG     YGG RGG+  GG  GGR  Y +  R
Sbjct: 550 GGDRSGGGYGGDRGG----GYGGDRGGY--GGKMGGRNDYRNDQR 588


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  110 bits (274), Expect = 4e-24
 Identities = 72/159 (45%), Positives = 77/159 (48%), Gaps = 15/159 (9%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGG 393
           GGRGG  G Y   S GG GG   GGG GG  G   G RGG       GG   GGSG GGG
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS------GGSYGGGSGSGGG 529

Query: 394 YQDGGY--RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
              GGY     G   GG  GGHS G   GG YGG   S   +G GY GG     +R   G
Sbjct: 530 -SGGGYGGGSGGGHSGGSGGGHSGG--SGGNYGGGSGSGGGSGGGYGGG---SGSRGGSG 583

Query: 452 GHHGDRGGGRGGRGGRGGRGGRA-GQGGGWGGRGSQNYH 489
           G HG   G  G  GG  G G  A G GGG+GG   ++ H
Sbjct: 584 GSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSH 622



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 73/181 (40%), Positives = 77/181 (42%), Gaps = 29/181 (16%)

Query: 338 GGRGGYEHSSYGGRGGHEQGGGRGGRGG-YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQD 396
           GG+  +E S  G  G     GGRGG GG Y  G RGG            GGS GGGG   
Sbjct: 460 GGQEDFESSGAGKIGL----GGRGGSGGSYGRGSRGGS-----------GGSYGGGG--- 501

Query: 397 GGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGD 456
                SG   GGY GG  S G  GG YGG   S   +G GY GG     +    GGH G 
Sbjct: 502 -----SG---GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGG 553

Query: 457 RGGGRGGRGGRGGRGGRAGQGGGWGGR-GSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRH 515
            GG  GG  G GG G   G GGG G R GS   H GG        G Y       G G  
Sbjct: 554 SGGNYGGGSGSGG-GSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG 612

Query: 516 Y 516
           Y
Sbjct: 613 Y 613



 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 57/132 (43%), Positives = 63/132 (47%), Gaps = 23/132 (17%)

Query: 333 TGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGG-RGGGRGNKHQGGWTDGGSGGG 391
           +GG GGG      S YGG      G G GG  GY +GG  GGG      GG   GGS G 
Sbjct: 38  SGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGF 97

Query: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
           GG   GGY  SG   GG+ GG S GG+ GGGY          GSG+  GG+        G
Sbjct: 98  GGASGGGYSSSGGFGGGFGGG-SGGGF-GGGY----------GSGF--GGF--------G 135

Query: 452 GHHGDRGGGRGG 463
           G  G  GGG GG
Sbjct: 136 GFGGGAGGGDGG 147



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 45/103 (43%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 333 TGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSG--G 390
           +G  GG  GGY   S GG  G   GG  GG GG   GG G G G+   GG   GGSG  G
Sbjct: 524 SGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS---GGGYGGGSGSRG 580

Query: 391 GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT 433
           G G   GG    G + GG +GG       GGGYGG    SS++
Sbjct: 581 GSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 60/153 (39%), Positives = 68/153 (44%), Gaps = 29/153 (18%)

Query: 346 SSYGGRGGHEQGGGRGGRGG-------YDHGGRGGGRGNKHQGGWTDGGS------GGGG 392
           SSY  R G   GGG G  G        +   G GGG G         GGS      GGGG
Sbjct: 8   SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67

Query: 393 GYQDGGYRDSGFQPGGYHGGHSSGGYQGG--GYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
            +   GY   G   GG+      GG+ GG  G+GG  +   Y+ SG  GGG+        
Sbjct: 68  SF---GYSYGGGSGGGFSASSLGGGFGGGSRGFGG-ASGGGYSSSGGFGGGF-------G 116

Query: 451 GGHHGDRGGGRG-GRGGRGGRGGRAGQGGGWGG 482
           GG  G  GGG G G GG GG GG  G GGG GG
Sbjct: 117 GGSGGGFGGGYGSGFGGFGGFGG--GAGGGDGG 147



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 47/107 (43%), Positives = 54/107 (50%), Gaps = 13/107 (12%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGGRGG----HEQGGGRGGRGGYDHGGRGGGRGNKHQGGW 383
           G   +  GRGGG G + +S  GG GG       GGG GG G    GG  GG G    GG+
Sbjct: 55  GGSSRVCGRGGG-GSFGYSYGGGSGGGFSASSLGGGFGG-GSRGFGGASGG-GYSSSGGF 111

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSS 430
             G  GG GG   GGY  SGF  GG+ G    GG  GGG GG  T++
Sbjct: 112 GGGFGGGSGGGFGGGY-GSGF--GGFGG---FGGGAGGGDGGILTAN 152



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 48/130 (36%), Positives = 51/130 (39%), Gaps = 13/130 (10%)

Query: 386 GGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGY----QGGG 441
           GG GGGG    G  R S      Y    SSGG  GGG G F +SS Y G       +GGG
Sbjct: 15  GGGGGGGLGSGGSIRSS------YSRFSSSGG--GGGGGRFSSSSGYGGGSSRVCGRGGG 66

Query: 442 YQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHG 501
                 Y  G   G      GG  G G RG     GGG+   G      GG     F  G
Sbjct: 67  GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGF-GG 125

Query: 502 GYQYNHSGFG 511
           GY     GFG
Sbjct: 126 GYGSGFGGFG 135



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 50/132 (37%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 388 SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNR 447
           SGGGGG   GG    G     Y    SSGG  GGG G F +SS     GY GG  +   R
Sbjct: 14  SGGGGG---GGLGSGGSIRSSYSRFSSSGG--GGGGGRFSSSS-----GYGGGSSRVCGR 63

Query: 448 YQDGGHHGDRGGGRGGRGGRGGRGGRAGQGG-GWGGRGSQNYHQGGQFEQHFQHGGYQYN 506
              G      GGG GG       GG  G G  G+GG     Y   G F   F  G     
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG----- 118

Query: 507 HSGFGQGRHYTS 518
            SG G G  Y S
Sbjct: 119 -SGGGFGGGYGS 129



 Score = 36.2 bits (82), Expect = 0.074
 Identities = 36/104 (34%), Positives = 41/104 (39%), Gaps = 13/104 (12%)

Query: 427 QTSSSYTG--SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGR----GGRGGRAGQGGGW 480
           Q SSSY     G  GGG       +         GG GG GGR     G GG + +  G 
Sbjct: 5   QFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGG-GGRFSSSSGYGGGSSRVCGR 63

Query: 481 GGRGSQNYH----QGGQFEQHFQHGGYQYNHSGFG--QGRHYTS 518
           GG GS  Y      GG F      GG+     GFG   G  Y+S
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSS 107


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score =  105 bits (261), Expect = 1e-22
 Identities = 74/182 (40%), Positives = 88/182 (48%), Gaps = 24/182 (13%)

Query: 323 QKRQDGPQQQTGGRGGGRGGY--EHSSYGGRGGH-EQGGGRGGRGGYDHGGRGGGRGNKH 379
           Q+ Q    Q+  GRGGG G +     ++GG GG+  +GG  GGRGGY  GG GGG    +
Sbjct: 205 QEMQSAGSQR--GRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGY--GGGGGGSRGSY 260

Query: 380 QGGWTDGGSGGGGGYQDGGYRDSG---FQPGGYHGGHSSGGYQGGGYGGFQTSSSYT-GS 435
            GG  DGG  G GG  DGG    G      GGY GG    G QGGGYGG      Y  G 
Sbjct: 261 GGG--DGGYNGFGG--DGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGG 316

Query: 436 GYQGGGYQQDNRYQDGGHHGD---------RGGGRGGRGGRGGRGGRAGQGGGWGGRGSQ 486
            + GG Y     Y D G++           +GG  GGR      GG  G GGG GG GS+
Sbjct: 317 NFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSR 376

Query: 487 NY 488
            +
Sbjct: 377 RF 378



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/95 (35%), Positives = 43/95 (45%), Gaps = 20/95 (21%)

Query: 427 QTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGG--GRGGR-GGRGGRGGRAGQGGGWGGR 483
           Q++ S  G G   G +        GG+ G  GG  GRGG  GGRGG G     GGG G R
Sbjct: 208 QSAGSQRGRGGGSGNFMGR-----GGNFGGGGGNFGRGGNFGGRGGYG-----GGGGGSR 257

Query: 484 GSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS 518
           GS     GG       + G+  +   +G G  Y+S
Sbjct: 258 GSYGGGDGG-------YNGFGGDGGNYGGGPGYSS 285


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  104 bits (260), Expect = 2e-22
 Identities = 77/202 (38%), Positives = 94/202 (46%), Gaps = 30/202 (14%)

Query: 323 QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           Q+ + G     GGRGGG GG ++    GRGG+    GRGG GG   GG  GG G+ + G 
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNF---GRGGNF--SGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
             DGG GGGG    GG R       GY  G    G QG GYGG  +  SY   G  GGG+
Sbjct: 248 GNDGGYGGGGPGYSGGSR-------GYGSGGQGYGNQGSGYGGSGSYDSYNNGG--GGGF 298

Query: 443 QQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAG-----QGGGWGGRGSQNYHQGGQ-FEQ 496
                   GG  G   GG G     G    ++      +GG +GGR S  Y  GGQ F +
Sbjct: 299 --------GGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAK 350

Query: 497 HFQHGGY--QYNHSGFGQGRHY 516
               GGY    + S +G GR +
Sbjct: 351 PRNQGGYGGSSSSSSYGSGRRF 372



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 7/76 (9%)

Query: 443 QQDNRYQDGGHHGDRGGGRGGRGGRGGRGG--RAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
           +Q+         G  G G  G G  GG GG    G+GG + GRG     +GG       +
Sbjct: 183 KQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGG-----GY 237

Query: 501 GGYQYNHSGFGQGRHY 516
           GG    ++GFG    Y
Sbjct: 238 GGSGDGYNGFGNDGGY 253


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 60/132 (45%), Positives = 67/132 (50%), Gaps = 19/132 (14%)

Query: 359 GRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGY 418
           G G  GG   GGRGGG      GG + GG   GGG+  G    SG   GGY GG S GG 
Sbjct: 455 GEGSSGG---GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG---GGYGGGSSGGGS 508

Query: 419 QGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGG 478
            GGGYGG  +S  + GS    GGY        GG  G  GGG GG GG G  GG +  GG
Sbjct: 509 SGGGYGGGSSSGGHGGS--SSGGY--------GG--GSSGGGGGGYGG-GSSGGGSSSGG 555

Query: 479 GWGGRGSQNYHQ 490
           G+GG  S   H+
Sbjct: 556 GYGGGSSSGGHK 567



 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 61/140 (43%), Positives = 66/140 (47%), Gaps = 21/140 (15%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGR--GGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG 391
           GGRGGG  G      GG GG   GGG   GG GG   G  GGG G    GG + GG G G
Sbjct: 462 GGRGGGSFG------GGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGG-GYG 514

Query: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQT-SSSYTGSGYQGGGYQQDNRYQD 450
           GG   GG+   G   GGY GG S GG  GGGYGG  +   S +G GY GG          
Sbjct: 515 GGSSSGGH--GGSSSGGYGGGSSGGG--GGGYGGGSSGGGSSSGGGYGGGS-------SS 563

Query: 451 GGHHGDRGGGRGGRGGRGGR 470
           GGH     G  G    +G R
Sbjct: 564 GGHKSSSSGSVGESSSKGPR 583



 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 59/147 (40%), Positives = 63/147 (42%), Gaps = 24/147 (16%)

Query: 337 GGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQD 396
           GGGRGG      G  GG   GG  G  GG   GG GGG G    GG+  GG   GGG   
Sbjct: 461 GGGRGG------GSFGGGYGGGSSG--GGSSGGGHGGGHGGSSGGGY--GGGSSGGGSSG 510

Query: 397 GGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGD 456
           GGY   G    G HGG SSGGY GG  GG        G G  GGG         GG+   
Sbjct: 511 GGY--GGGSSSGGHGGSSSGGYGGGSSGG--------GGGGYGGGSSGGGSSSGGGY--- 557

Query: 457 RGGGRGGRGGRGGRGGRAGQGGGWGGR 483
            GGG    G +    G  G+    G R
Sbjct: 558 -GGGSSSGGHKSSSSGSVGESSSKGPR 583



 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 56/134 (41%), Positives = 67/134 (50%), Gaps = 19/134 (14%)

Query: 380 QGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSY----TGS 435
           +G  + GG G GGG   GGY       GG  GG SSGG  GGG+GG  +   Y    +G 
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYG------GGSSGGGSSGGGHGGGHGG-SSGGGYGGGSSGG 506

Query: 436 GYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFE 495
           G  GGGY   +    GGH G   GG GG G  GG GG  G GGG  G GS +   GG + 
Sbjct: 507 GSSGGGYGGGS--SSGGHGGSSSGGYGG-GSSGGGGG--GYGGGSSGGGSSS---GGGYG 558

Query: 496 QHFQHGGYQYNHSG 509
                GG++ + SG
Sbjct: 559 GGSSSGGHKSSSSG 572



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 56/146 (38%), Positives = 63/146 (43%), Gaps = 21/146 (14%)

Query: 343 YEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDS 402
           Y  S  GG GG   GGG GG GG         +G+             GGG+  GG+   
Sbjct: 11  YSSSRSGGGGG---GGGCGGGGGVSSLRISSSKGSL------------GGGFSSGGFSGG 55

Query: 403 GFQPGGYHG---GHSSGGYQG-GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRG 458
            F  G   G   G SSGGY G GG+GG     SY  S + G           GG  G  G
Sbjct: 56  SFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG--GSFG 113

Query: 459 GGRGGRGGRGGRGGRAGQGGGWGGRG 484
           GG  G GG GG G   G GGG+GG G
Sbjct: 114 GGSFGGGGFGGGGFGGGFGGGFGGDG 139



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 57/147 (38%), Positives = 64/147 (43%), Gaps = 33/147 (22%)

Query: 334 GGRGGGRGGYE-------HSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDG 386
           GG GGG GG          SS G  GG    GG  G G +  G  GGG      GG+  G
Sbjct: 19  GGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSG-GSFSRGSSGGGCFGGSSGGY--G 75

Query: 387 GSGG-GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQD 445
           G GG GGG   G Y  S F  G Y G    G + GG +GG     S+ G G+ GGG+   
Sbjct: 76  GLGGFGGGSFRGSYGSSSFG-GSYGGSFGGGSFGGGSFGG----GSFGGGGFGGGGF--- 127

Query: 446 NRYQDGGHHGDRGGGRGGRGGRGGRGG 472
                       GGG GG  G GG GG
Sbjct: 128 ------------GGGFGG--GFGGDGG 140



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 50/130 (38%), Positives = 58/130 (44%), Gaps = 17/130 (13%)

Query: 377 NKHQGGWTDGGSGGGGGYQDGGYRDS------------GFQPGGYHGGHSSGGYQGGG-Y 423
           +KH      GG GGGGG   GG   S            GF  GG+ GG  S G  GGG +
Sbjct: 8   SKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCF 67

Query: 424 GGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG-GRGGRGGRAGQGGGWGG 482
           GG  +S  Y G G  GGG  + + Y      G  GG  GG   G G  GG +  GGG+GG
Sbjct: 68  GG--SSGGYGGLGGFGGGSFRGS-YGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGG 124

Query: 483 RGSQNYHQGG 492
            G      GG
Sbjct: 125 GGFGGGFGGG 134



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 56/141 (39%), Positives = 60/141 (42%), Gaps = 34/141 (24%)

Query: 385 DGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQ 444
           +G SGGGG       R  G   GGY GG S GG  GGG+GG    SS       GGGY  
Sbjct: 456 EGSSGGGG-------RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSS-------GGGY-- 499

Query: 445 DNRYQDGGHHGDRGGGR--GGRGG---RGGRGGRA--GQGGGWGGRGSQNYHQGGQFEQH 497
                 GG  G  GGG   GG GG    GG GG +  G GGG  G G   Y  G      
Sbjct: 500 ------GG--GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGS 551

Query: 498 FQHGGYQYNHSGFGQGRHYTS 518
              GGY     G   G H +S
Sbjct: 552 SSGGGY---GGGSSSGGHKSS 569



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/90 (38%), Positives = 39/90 (43%), Gaps = 22/90 (24%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
           G    +GG GG       SS GG GG   GGG GG GG   G  GGG         +  G
Sbjct: 514 GGGSSSGGHGG-------SSSGGYGGGSSGGGGGGYGG---GSSGGG---------SSSG 554

Query: 388 SGGGGGYQDGGYRDSGFQPGGYHGGHSSGG 417
            G GGG   GG++ S     G  G  SS G
Sbjct: 555 GGYGGGSSSGGHKSSS---SGSVGESSSKG 581



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 33/76 (43%), Positives = 35/76 (46%), Gaps = 11/76 (14%)

Query: 334 GGRGGG--RGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG 391
           GG GGG  RG Y  SS+GG  G   GGG  G G       GGG      GG   GG G G
Sbjct: 78  GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGG-----SFGGG----SFGGGGFGGGGFG 128

Query: 392 GGYQDGGYRDSGFQPG 407
           GG+  G   D G   G
Sbjct: 129 GGFGGGFGGDGGLLSG 144



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 434 GSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
           G G  GGG +    +  G   G  GGG  G GG GG G     GGG+GG  S     GG 
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSG-GGHGG-GHGGSSGGGYGGGSSGGGSSGGG 512

Query: 494 FEQHFQHGGYQYNHS-GFGQG 513
           +      GG+  + S G+G G
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGG 533



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 6/69 (8%)

Query: 447 RYQDGGHHGDRGGGRGGRGGRGGRGGR------AGQGGGWGGRGSQNYHQGGQFEQHFQH 500
           RY    H+     G GG GG  G GG       +   G  GG  S     GG F +    
Sbjct: 4   RYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63

Query: 501 GGYQYNHSG 509
           GG     SG
Sbjct: 64  GGCFGGSSG 72


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 76/213 (35%), Positives = 89/213 (41%), Gaps = 22/213 (10%)

Query: 305 RGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQ----GGGR 360
           RGGR     PPPP  PP++  + G  +  GG   GRGG      GG GGH      GGG 
Sbjct: 707 RGGRGGNEPPPPP--PPFRGARGG--RSGGGPPNGRGGPGGGMVGG-GGHRPHEGPGGGM 761

Query: 361 GGRGGY-DHGGRGGGRGNKHQGGWTDGGS-GGGGGYQDGGYRDSGFQPGGYHGGHSSGGY 418
           G   G+  H G GGG G+ H+     GGS GGGGG++       G   G  H  H   G 
Sbjct: 762 GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGG 821

Query: 419 QGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG-----GR 473
             G  GG +      GS    GG++       GG HG R     G  G   RG      R
Sbjct: 822 GMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHR 881

Query: 474 AGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYN 506
              G G GG G +  H GG       HGG   N
Sbjct: 882 GHDGPGHGGGGHRG-HDGGH-----SHGGDMSN 908



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/206 (29%), Positives = 71/206 (34%), Gaps = 47/206 (22%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRGNK-------HQGG---W 383
           G G    G+     GG  G +    G GG     HGG GG  G +        +GG   W
Sbjct: 621 GPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFW 680

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSS---YTGS-GYQG 439
              G    GG   GG    G  PG YH G        GG GG +       + G+ G + 
Sbjct: 681 DGPGDPMRGGPMRGG---PGPGPGPYHRGR-------GGRGGNEPPPPPPPFRGARGGRS 730

Query: 440 GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQ---GGQFEQ 496
           GG   + R       G  GGG     G GG     G GGG G       H+   GG    
Sbjct: 731 GGGPPNGR-------GGPGGGMV---GGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSG 780

Query: 497 HFQH---------GGYQYNHSGFGQG 513
           H  H         GG    H G G G
Sbjct: 781 HRPHEGPGGSMGGGGGHRPHEGPGGG 806


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 78/214 (36%), Positives = 83/214 (38%), Gaps = 39/214 (18%)

Query: 322 WQKRQDGPQQQT----------GGRGGGRGGYEHSSYGGRGGHEQGGGRG--GRGGYDHG 369
           +QK+Q  PQ             GG G G GG      GG GG   G G G  G GGY  G
Sbjct: 3   YQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGG 62

Query: 370 GRGGGRGNKHQGGWTDGGSGGGGG---YQDGGYRDSG----FQPGGYHGG---HSSGGYQ 419
           G GGG      GG   G  GG GG   Y  GG    G    F  GG   G      GG  
Sbjct: 63  GCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSS 122

Query: 420 GGGYGGFQT---SSSYTGSG---YQGGGYQ----QDNRYQDGGHHGDRGGGRG--GRGGR 467
           GGG G F +    SS  GSG     GGG+     Q   Y      G  GGG G    GG 
Sbjct: 123 GGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGG 182

Query: 468 GG-----RGGRAGQGGGWGGRGSQNYHQGGQFEQ 496
           GG      GG +G GGG  G     Y    Q  Q
Sbjct: 183 GGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQ 216



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 62/179 (34%), Positives = 69/179 (38%), Gaps = 28/179 (15%)

Query: 334 GGRGGGRGGYEHSSYGG----------RGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGW 383
           GG  GG  G   S  GG           GG   GG  GG  G    G GGG       G+
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGS----VCGY 189

Query: 384 TDGGSGGGGGYQDG---GYRDS------GFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
           + GGSG GGG   G   GY  S         P   +GG SSGG   GG G F +      
Sbjct: 190 SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGS 249

Query: 435 SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
           SG  GG     +     G     GG   G G  GG GG +  GG   G+G    HQ  Q
Sbjct: 250 SGCGGGSSGIGSGCIISG-----GGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQ 303



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 54/138 (39%), Positives = 59/138 (42%), Gaps = 16/138 (11%)

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSG---------GYQGGGYGGFQTSSSYTG 434
           T GG GGGGG   GG    GF  GG  GG SSG         GY GGG GG  +     G
Sbjct: 19  TSGGGGGGGGSGGGG---CGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGG 75

Query: 435 S-GYQGGGYQQDNRYQDGGHHGDRGGGRG-GRGGRGGRGGRAGQGGGWGGRGSQNYHQGG 492
             G  GGG     +Y  GG  G  GGG G    G GG G  +  GGG  G GS  +  GG
Sbjct: 76  GIGGCGGGSGGSVKYSGGG--GSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133

Query: 493 QFEQHFQHGGYQYNHSGF 510
                   G +     GF
Sbjct: 134 GGSSGGGSGCFSSGGGGF 151



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 31/74 (41%), Positives = 31/74 (41%), Gaps = 5/74 (6%)

Query: 329 PQQQTGGR---GGGRGGYEHSSYGGRGGHEQ-GGGRGGRG-GYDHGGRGGGRGNKHQGGW 383
           PQ   GG    GGG GG    S GG GG    GGG  G G G    G G   G    GG 
Sbjct: 221 PQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGG 280

Query: 384 TDGGSGGGGGYQDG 397
             G S GG G   G
Sbjct: 281 GGGSSVGGSGSGKG 294


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 61/140 (43%), Positives = 64/140 (45%), Gaps = 31/140 (22%)

Query: 334 GGRGGGRGGYEH--SSYGGRGGH--EQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSG 389
           G RGGG GGY    SSYG  GG     GGG GGRG Y  GG   G      GG + G  G
Sbjct: 516 GSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYG-----SGGGSYGSGG 570

Query: 390 GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQ 449
           GGGG+            G Y  G SSGGY+GG  GG   SS   GSG  GG         
Sbjct: 571 GGGGH------------GSYGSGSSSGGYRGGSGGGGGGSSGGRGSG--GG--------S 608

Query: 450 DGGHHGDRGGGRGGRGGRGG 469
            GG  G RG   GG    GG
Sbjct: 609 SGGSIGGRGSSSGGVKSSGG 628



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 58/143 (40%), Positives = 68/143 (47%), Gaps = 31/143 (21%)

Query: 345 HSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGF 404
           H++  G G    GGG  G GG  +G  GG  G+   GG   GG GG G Y  GG   S +
Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGS---GG---GGGGGRGSYGSGG---SSY 559

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGR 464
             GG  G + SGG  GGG+G +       GSG   GGY+       GG  G  GG  GGR
Sbjct: 560 GSGG--GSYGSGG-GGGGHGSY-------GSGSSSGGYR-------GGSGGGGGGSSGGR 602

Query: 465 GGRGGRGGRAGQGGGWGGRGSQN 487
           G  GG       GG  GGRGS +
Sbjct: 603 GSGGG-----SSGGSIGGRGSSS 620



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 45/107 (42%), Positives = 50/107 (46%), Gaps = 18/107 (16%)

Query: 336 RGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGG---------RGGGRGNKHQGGWTDG 386
           R GG GG   S  GG G    GGG G R   + GG         RGGGRG+   GG+  G
Sbjct: 38  RSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGG 97

Query: 387 GSGGGG---------GYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYG 424
           G GGGG         G   GG+   G   GG+ GG   GG  GGGYG
Sbjct: 98  GFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 48/107 (44%), Positives = 54/107 (50%), Gaps = 14/107 (13%)

Query: 334 GGRGGGRGGYEH--SSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG 391
           GG GGGRG Y    SSYG  GG    GG GG     HG  G G  +   GG+  GGSGGG
Sbjct: 543 GGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG----GHGSYGSGSSS---GGYR-GGSGGG 594

Query: 392 GGYQDGGYRDSGFQPGGYHGGH--SSGGYQ--GGGYGGFQTSSSYTG 434
           GG   GG    G   GG  GG   SSGG +  GG       S++Y+G
Sbjct: 595 GGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSG 641



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 48/125 (38%), Positives = 53/125 (42%), Gaps = 31/125 (24%)

Query: 322 WQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGG---------------------R 360
           +Q+R      +  G GGGR     SS GG GG    GG                     R
Sbjct: 27  YQRRTTSSSTRRSGGGGGR----FSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVAR 82

Query: 361 GGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420
           GG  G   GG  GG G    GG   GG  GGGG   GG+   GF  GG  GG   GG+ G
Sbjct: 83  GGGRGSGFGGGYGGGG--FGGGGFGGGGFGGGGIGGGGF--GGFGSGG--GGFGGGGFGG 136

Query: 421 GGYGG 425
           GGYGG
Sbjct: 137 GGYGG 141



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 43/108 (39%), Positives = 47/108 (43%), Gaps = 23/108 (21%)

Query: 410 HGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
           H   S GG +GGG GG+ +  S  GSG  GG Y         G  G  GGGRG  G  G 
Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSG--GGSY---------GSGGGGGGGRGSYGSGGS 557

Query: 470 R----GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQG 513
                GG  G GGG GG GS  Y  G         GGY+    G G G
Sbjct: 558 SYGSGGGSYGSGGGGGGHGS--YGSGS------SSGGYRGGSGGGGGG 597



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 49/144 (34%), Positives = 55/144 (38%), Gaps = 19/144 (13%)

Query: 375 RGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
           R     GG    GS G   YQ      S  + GG  G  SS G  GG +G          
Sbjct: 8   RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGA--------- 58

Query: 435 SGYQGGGYQQDNRYQDGGHHG-----DRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYH 489
               GGG+   +    GG         RGGGRG   G GG GG    GGG+GG G     
Sbjct: 59  ----GGGFGSRSLVNLGGSKSISISVARGGGRGSGFG-GGYGGGGFGGGGFGGGGFGGGG 113

Query: 490 QGGQFEQHFQHGGYQYNHSGFGQG 513
            GG     F  GG  +   GFG G
Sbjct: 114 IGGGGFGGFGSGGGGFGGGGFGGG 137



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 38/86 (44%), Positives = 42/86 (48%), Gaps = 16/86 (18%)

Query: 336 RGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQ 395
           RGGGRG      YGG G    GGG  G GG+  GG GGG       G+  GG G GG   
Sbjct: 82  RGGGRGSGFGGGYGGGGF---GGGGFGGGGFGGGGIGGG-------GF--GGFGSGG--- 126

Query: 396 DGGYRDSGFQPGGYHGGHSSGGYQGG 421
            GG+   GF  GGY GG+      GG
Sbjct: 127 -GGFGGGGFGGGGYGGGYGPVCPPGG 151



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 35/81 (43%), Positives = 38/81 (46%), Gaps = 8/81 (9%)

Query: 334 GGRGGG-RGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG- 391
           GGRG G  GGY    +GG G    G G GG GG   GG G G G    GG+  GG GGG 
Sbjct: 84  GGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY 143

Query: 392 ------GGYQDGGYRDSGFQP 406
                 GG Q+     S  QP
Sbjct: 144 GPVCPPGGIQEVTINQSLLQP 164


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 76/250 (30%), Positives = 90/250 (36%), Gaps = 53/250 (21%)

Query: 307 GRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRG---GHEQGGGRGGR 363
           G P   E PPP  P  + R  G   +  GRG G GG  H  Y   G   G    GG    
Sbjct: 630 GGPMHNEVPPP--PNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSAT 687

Query: 364 GGYDHGGRGGGRGNKHQGGWTDGGSGGGGG-------YQDGGYRD-------------SG 403
            GY      GG    H G  + GG GGGGG       YQ   Y                G
Sbjct: 688 AGYSQFYSNGG----HSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGG 743

Query: 404 FQPGGYHGGHSSG-------------------GYQGG---GYGGFQTSSSYTGSGYQGGG 441
            Q   Y  G+ S                    G Q G   G G +  S+SY   G  GG 
Sbjct: 744 QQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 803

Query: 442 -YQQDNRYQDGGHHGDRGGGRGGRGGRG-GRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQ 499
            Y  ++++   G  G  GG   G GG     G   G GGG GG  S    QGG  + ++ 
Sbjct: 804 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 863

Query: 500 HGGYQYNHSG 509
             G   N+SG
Sbjct: 864 SPGSGQNYSG 873



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 54/162 (33%), Positives = 68/162 (41%), Gaps = 10/162 (6%)

Query: 362 GRGGYDHG-GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420
           GRGG   G GRG G G  + GG+ + G+G G     G    +G+     +GGHS     G
Sbjct: 647 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGG 706

Query: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480
           GG GG    SS  GS YQG  Y      +  G     GG +    G G +    GQ   +
Sbjct: 707 GGGGG--GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQ-SHQGQQQSY 763

Query: 481 GGRGSQNY--HQGGQFEQHFQHGGYQYNHS----GFGQGRHY 516
                 NY   QG Q   +   G Y Y++S    G G G  Y
Sbjct: 764 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDY 805



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 10/170 (5%)

Query: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369
           N   P PP+    ++   G Q+ + G G      +  SY        G  +G + GY+HG
Sbjct: 725 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG 784

Query: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQ---DGGYRDSGFQPGGYHGGHSSGGYQGGGYGGF 426
                  N +       G GGG  Y       Y  SG + GG   G     Y  G +GG+
Sbjct: 785 QGSYSYSNSYNSP----GGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY 840

Query: 427 QTSSSYTGSGYQG--GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474
              S   GS YQG  GGY Q N    G      G     +  +GG G  A
Sbjct: 841 GGGSG-GGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNA 889



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 7/76 (9%)

Query: 328 GPQQQTGGRGGGRGG--YEHSSYGGRGGHEQG-----GGRGGRGGYDHGGRGGGRGNKHQ 380
           G   ++GG   G GG  Y   S+GG GG   G     G +GG    ++   G G+     
Sbjct: 815 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGP 874

Query: 381 GGWTDGGSGGGGGYQD 396
                   GG G   D
Sbjct: 875 PSSYQSSQGGYGRNAD 890


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 76/250 (30%), Positives = 90/250 (36%), Gaps = 53/250 (21%)

Query: 307 GRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRG---GHEQGGGRGGR 363
           G P   E PPP  P  + R  G   +  GRG G GG  H  Y   G   G    GG    
Sbjct: 626 GGPMHNEVPPP--PNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSAT 683

Query: 364 GGYDHGGRGGGRGNKHQGGWTDGGSGGGGG-------YQDGGYRD-------------SG 403
            GY      GG    H G  + GG GGGGG       YQ   Y                G
Sbjct: 684 AGYSQFYSNGG----HSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGG 739

Query: 404 FQPGGYHGGHSSG-------------------GYQGG---GYGGFQTSSSYTGSGYQGGG 441
            Q   Y  G+ S                    G Q G   G G +  S+SY   G  GG 
Sbjct: 740 QQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 799

Query: 442 -YQQDNRYQDGGHHGDRGGGRGGRGGRG-GRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQ 499
            Y  ++++   G  G  GG   G GG     G   G GGG GG  S    QGG  + ++ 
Sbjct: 800 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 859

Query: 500 HGGYQYNHSG 509
             G   N+SG
Sbjct: 860 SPGSGQNYSG 869



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 54/162 (33%), Positives = 68/162 (41%), Gaps = 10/162 (6%)

Query: 362 GRGGYDHG-GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420
           GRGG   G GRG G G  + GG+ + G+G G     G    +G+     +GGHS     G
Sbjct: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGG 702

Query: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480
           GG GG    SS  GS YQG  Y      +  G     GG +    G G +    GQ   +
Sbjct: 703 GGGGG--GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQ-SHQGQQQSY 759

Query: 481 GGRGSQNY--HQGGQFEQHFQHGGYQYNHS----GFGQGRHY 516
                 NY   QG Q   +   G Y Y++S    G G G  Y
Sbjct: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDY 801



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 10/170 (5%)

Query: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369
           N   P PP+    ++   G Q+ + G G      +  SY        G  +G + GY+HG
Sbjct: 721 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG 780

Query: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQ---DGGYRDSGFQPGGYHGGHSSGGYQGGGYGGF 426
                  N +       G GGG  Y       Y  SG + GG   G     Y  G +GG+
Sbjct: 781 QGSYSYSNSYNSP----GGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY 836

Query: 427 QTSSSYTGSGYQG--GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474
              S   GS YQG  GGY Q N    G      G     +  +GG G  A
Sbjct: 837 GGGSG-GGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNA 885



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 7/76 (9%)

Query: 328 GPQQQTGGRGGGRGG--YEHSSYGGRGGHEQG-----GGRGGRGGYDHGGRGGGRGNKHQ 380
           G   ++GG   G GG  Y   S+GG GG   G     G +GG    ++   G G+     
Sbjct: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGP 870

Query: 381 GGWTDGGSGGGGGYQD 396
                   GG G   D
Sbjct: 871 PSSYQSSQGGYGRNAD 886


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 67/166 (40%), Positives = 74/166 (44%), Gaps = 24/166 (14%)

Query: 330 QQQTGGRGGGRGGYEHSSYGGRGGHEQGGG-RGGRGGYDHGGRGGGRGNKHQGGWTDGGS 388
           Q    GRGG  G  +    GG  G   G   RGG  GY   GRG G G    GG   GG+
Sbjct: 197 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYG-SGRGFGDGYNGYGGGPGGGN 255

Query: 389 -GGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY----- 442
            GG  GY  GG R      GGY GG    G QGGGYGG     +Y G  Y  G Y     
Sbjct: 256 FGGSPGY--GGGR------GGYGGGGPGYGNQGGGYGG--GYDNYGGGNYGSGNYNDFGN 305

Query: 443 --QQDNRY---QDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGR 483
             QQ + Y   + G   G R  G    GG  G GG +G  GG+GGR
Sbjct: 306 YNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGG-SGGSGGYGGR 350



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 62/172 (36%), Positives = 74/172 (43%), Gaps = 23/172 (13%)

Query: 346 SSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGF 404
           SS  GRGG+   G  RGG G +     G G G+  +GG    G G G G+ DG Y   G 
Sbjct: 198 SSRSGRGGNFGFGDSRGGGGNF-----GPGPGSNFRGG--SDGYGSGRGFGDG-YNGYGG 249

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGR 464
            PGG + G S G   GGG GG+       G G QGGGY        GG + + GGG  G 
Sbjct: 250 GPGGGNFGGSPG--YGGGRGGY--GGGGPGYGNQGGGY--------GGGYDNYGGGNYGS 297

Query: 465 GGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHY 516
           G     G    Q   +G   S N+  GG       +GG  Y   G G    Y
Sbjct: 298 GNYNDFGNYNQQPSNYGPMKSGNF--GGSRNMGGPYGGGNYGPGGSGGSGGY 347



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 58/149 (38%), Positives = 64/149 (42%), Gaps = 39/149 (26%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGR----GGGRGNKHQGGWTDGG--S 388
           G G GRG  +   Y G GG   GG  GG  GY  GGR    GGG G  +QGG   GG  +
Sbjct: 233 GYGSGRGFGD--GYNGYGGGPGGGNFGGSPGYG-GGRGGYGGGGPGYGNQGGGYGGGYDN 289

Query: 389 GGGGGYQDGGYRDSG---FQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQD 445
            GGG Y  G Y D G    QP  Y      G  + G +GG    S   G  Y GG Y   
Sbjct: 290 YGGGNYGSGNYNDFGNYNQQPSNY------GPMKSGNFGG----SRNMGGPYGGGNY--- 336

Query: 446 NRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474
                         G GG GG GG GGR+
Sbjct: 337 --------------GPGGSGGSGGYGGRS 351


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 67/166 (40%), Positives = 74/166 (44%), Gaps = 24/166 (14%)

Query: 330 QQQTGGRGGGRGGYEHSSYGGRGGHEQGGG-RGGRGGYDHGGRGGGRGNKHQGGWTDGGS 388
           Q    GRGG  G  +    GG  G   G   RGG  GY   GRG G G    GG   GG+
Sbjct: 185 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYG-SGRGFGDGYNGYGGGPGGGN 243

Query: 389 -GGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY----- 442
            GG  GY  GG R      GGY GG    G QGGGYGG     +Y G  Y  G Y     
Sbjct: 244 FGGSPGY--GGGR------GGYGGGGPGYGNQGGGYGG--GYDNYGGGNYGSGNYNDFGN 293

Query: 443 --QQDNRY---QDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGR 483
             QQ + Y   + G   G R  G    GG  G GG +G  GG+GGR
Sbjct: 294 YNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGG-SGGSGGYGGR 338



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 62/172 (36%), Positives = 74/172 (43%), Gaps = 23/172 (13%)

Query: 346 SSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGF 404
           SS  GRGG+   G  RGG G +     G G G+  +GG    G G G G+ DG Y   G 
Sbjct: 186 SSRSGRGGNFGFGDSRGGGGNF-----GPGPGSNFRGG--SDGYGSGRGFGDG-YNGYGG 237

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGR 464
            PGG + G S G   GGG GG+       G G QGGGY        GG + + GGG  G 
Sbjct: 238 GPGGGNFGGSPG--YGGGRGGY--GGGGPGYGNQGGGY--------GGGYDNYGGGNYGS 285

Query: 465 GGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHY 516
           G     G    Q   +G   S N+  GG       +GG  Y   G G    Y
Sbjct: 286 GNYNDFGNYNQQPSNYGPMKSGNF--GGSRNMGGPYGGGNYGPGGSGGSGGY 335



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 58/149 (38%), Positives = 64/149 (42%), Gaps = 39/149 (26%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGR----GGGRGNKHQGGWTDGG--S 388
           G G GRG  +   Y G GG   GG  GG  GY  GGR    GGG G  +QGG   GG  +
Sbjct: 221 GYGSGRGFGD--GYNGYGGGPGGGNFGGSPGYG-GGRGGYGGGGPGYGNQGGGYGGGYDN 277

Query: 389 GGGGGYQDGGYRDSG---FQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQD 445
            GGG Y  G Y D G    QP  Y      G  + G +GG    S   G  Y GG Y   
Sbjct: 278 YGGGNYGSGNYNDFGNYNQQPSNY------GPMKSGNFGG----SRNMGGPYGGGNY--- 324

Query: 446 NRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474
                         G GG GG GG GGR+
Sbjct: 325 --------------GPGGSGGSGGYGGRS 339


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 64/207 (30%), Positives = 84/207 (40%), Gaps = 25/207 (12%)

Query: 328  GPQQQTGGRGGGRG---GYEHSSYGGR--GGHEQGGGRGGRGGYD-HGGRGGGRGNKHQG 381
            G    +G  G G G   G+ H S  G+  G  + G G G    Y+ HG R G      Q 
Sbjct: 914  GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973

Query: 382  GWTDG-----GSGGGGGYQDGGY----RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSY 432
            G + G     G  G G  Q  G+      SG  P    G H SG  Q   YG +++ S +
Sbjct: 974  GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033

Query: 433  TGSGYQGGGYQQDNRYQDG-GHHGDRGGGRGGRGGRGGRGGRA---GQGGGWGGRGS--- 485
            + S    G Y+  + +  G GH   R G   G G  G   G +   GQ G   G+ S   
Sbjct: 1034 SSS---RGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1090

Query: 486  QNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
            Q+    GQ   H QHG      SG+G+
Sbjct: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGR 1117



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 60/199 (30%), Positives = 74/199 (37%), Gaps = 14/199 (7%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGWTDG 386
           GP     G   G G +E SS    G  + G G G   G+  HG R G      + G + G
Sbjct: 453 GPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAG 512

Query: 387 GSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDN 446
            S   G +  G  +  G    G   G S    +G    G + SSSY   GY  G      
Sbjct: 513 SSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG 572

Query: 447 RYQDG-------GHHGDRGGGRGGRGGRGGRGGRA---GQGGGWGGRGS---QNYHQGGQ 493
            Y+ G       GH   R G   G G  G   G +   GQ G   G+ S   Q+    GQ
Sbjct: 573 PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQ 632

Query: 494 FEQHFQHGGYQYNHSGFGQ 512
              H QHG      S +GQ
Sbjct: 633 SSSHGQHGSGSSQSSRYGQ 651



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 61/192 (31%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQG 381
            Q    GP +   G    RG YE  S    G GH +       G   HG   G      Q 
Sbjct: 1020 QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT-GSGYQGG 440
            G T G S   G +     + S       HG H SG  Q  GYG   + S  + G G +G 
Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSS------HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1133

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G +Q   Y   G HG  G GR    G+ G G   G+  G+G   S +    GQ   + QH
Sbjct: 1134 GSRQSPSY---GRHGS-GSGRSSSSGQHGSG--LGESSGFGHHESSS----GQSSSYSQH 1183

Query: 501  GGYQYNHSGFGQ 512
            G    + SG+GQ
Sbjct: 1184 GSGSGHSSGYGQ 1195



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 63/192 (32%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQG-GGRGGRGGYDHGGRGGGRGNKHQG 381
            Q    GP     G    RG YE  S     GH  G G R  R G   G    G  + H  
Sbjct: 1960 QSSSYGPYGSGSGWSSSRGPYESGS-----GHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT-GSGYQGG 440
                 GS  G     G +  S  Q    HG H SG  Q  GYG   + S  + G G +G 
Sbjct: 2015 THGQHGSASGQSSSCGQHGASSGQSSS-HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2073

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G +Q   Y   G HG  G GR    G+ G G   G+  G+G   S +    GQ   + QH
Sbjct: 2074 GSRQSPSY---GRHGS-GSGRSSSSGQHGPG--LGESSGFGHHESSS----GQSSSYSQH 2123

Query: 501  GGYQYNHSGFGQ 512
            G    + SG+GQ
Sbjct: 2124 GSGSGHSSGYGQ 2135



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 60/192 (31%), Positives = 74/192 (38%), Gaps = 18/192 (9%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQG 381
            Q     P     G    RG YE  S    G GH +       G   HG   G      Q 
Sbjct: 1490 QSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1549

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT-GSGYQGG 440
            G T G S   G +     + S       HG H SG  Q  GYG   + S  + G G +G 
Sbjct: 1550 GSTSGQSSSCGQHGASSGQSSS------HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1603

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G +Q   Y   G HG  G GR    G+ G G   G+  G+G   S +    GQ   + QH
Sbjct: 1604 GSRQSPSY---GRHGS-GSGRSSSSGQHGSG--LGESSGFGHHESSS----GQSSSYSQH 1653

Query: 501  GGYQYNHSGFGQ 512
            G    + SG+GQ
Sbjct: 1654 GSGSGHSSGYGQ 1665



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 60/202 (29%), Positives = 81/202 (40%), Gaps = 34/202 (16%)

Query: 335  GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYD-HGGRGG--GRGNKH---QGGWTDGGS 388
            G+  G G +E SS+   G  + G G G    Y+ HG R G   RG +H    G  +  G 
Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925

Query: 389  GGGGGYQDGGYRD----SGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT--------GSG 436
             G G  Q  G+      SG  P    G H SG  Q   YG + + S ++        GSG
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSG 1985

Query: 437  YQGG-GYQQDNRYQDGGH--HGDRGGG---RGGRGGRGGRGGRAGQGGGWGGRGSQNYHQ 490
            +  G G+++    Q  G+  HG   G     G  G   G+    GQ G   G+ S     
Sbjct: 1986 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS----- 2040

Query: 491  GGQFEQHFQHGGYQYNHSGFGQ 512
                  H QHG      SG+G+
Sbjct: 2041 -----SHGQHGSGSSQSSGYGR 2057



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 56/190 (29%), Positives = 73/190 (38%), Gaps = 8/190 (4%)

Query: 335  GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYD-HGGRGG--GRGNKHQGGWTDGGSGGG 391
            G+  G G +E SS+   G  + G G G    Y+ HG R G   RG +H  G + G S   
Sbjct: 1396 GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERH--GSSSGSSSSY 1453

Query: 392  GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
            G +  G  +  G    G   G S    +G    G   SSSY+  G   G       Y+ G
Sbjct: 1454 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 1513

Query: 452  GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHG---GYQYNHS 508
              H    G R  R G+    G+ G   G      Q+    GQ     QHG   G   +H 
Sbjct: 1514 SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1573

Query: 509  GFGQGRHYTS 518
              G G   +S
Sbjct: 1574 QHGSGSSQSS 1583



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 60/192 (31%), Positives = 74/192 (38%), Gaps = 18/192 (9%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQG 381
            Q     P     G    RG YE  S    G GH +       G   HG   G      Q 
Sbjct: 2430 QSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 2489

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT-GSGYQGG 440
            G T G S   G +     + S       HG H SG  Q  GYG   + S  + G G +G 
Sbjct: 2490 GSTSGQSSSCGQHGASSGQSSS------HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2543

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G +Q   Y   G HG  G GR    G+ G G   G+  G+G   S +    GQ   + QH
Sbjct: 2544 GSRQSPSY---GRHGS-GSGRSSSSGQHGSG--LGESSGFGHHESSS----GQSSSYSQH 2593

Query: 501  GGYQYNHSGFGQ 512
            G    + SG+GQ
Sbjct: 2594 GSGSGHSSGYGQ 2605



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 56/190 (29%), Positives = 73/190 (38%), Gaps = 8/190 (4%)

Query: 335  GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYD-HGGRGG--GRGNKHQGGWTDGGSGGG 391
            G+  G G +E SS+   G  + G G G    Y+ HG R G   RG +H  G + G S   
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERH--GSSSGSSSSY 2393

Query: 392  GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
            G +  G  +  G    G   G S    +G    G   SSSY+  G   G       Y+ G
Sbjct: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453

Query: 452  GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHG---GYQYNHS 508
              H    G R  R G+    G+ G   G      Q+    GQ     QHG   G   +H 
Sbjct: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513

Query: 509  GFGQGRHYTS 518
              G G   +S
Sbjct: 2514 QHGSGSSQSS 2523



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 64/215 (29%), Positives = 77/215 (35%), Gaps = 31/215 (14%)

Query: 325  RQDGPQQQTGGRGGGRGGYEHSS----YGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQ 380
            +Q     Q+  RG    G  HSS    +G   G     GR G G     G G    +  Q
Sbjct: 2291 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQ 2350

Query: 381  -GGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGG----------HSSGGYQGGGYGGFQ 427
              G+T  GSG G    Y+  G R      G  HG           H SG  Q  G+G   
Sbjct: 2351 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHG 2410

Query: 428  TSSSYTGS---GYQGGGYQQDNRYQDGG-------HHGDRGGGRGGRGGRGGRGGRAGQG 477
            + S  + S   G  G G  Q + Y   G         G    G G   G G R  R+GQ 
Sbjct: 2411 SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS 2470

Query: 478  GGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
             G+G  GS + H       H QHG      S  GQ
Sbjct: 2471 SGYGQHGSSSGHS----STHGQHGSTSGQSSSCGQ 2501



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 56/201 (27%), Positives = 71/201 (35%), Gaps = 17/201 (8%)

Query: 327 DGPQQQTGGRGGGRGGYEHSSYGGR--GGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGW 383
           +GP     G+  G G   H S  G+  G  + G G     GY  HG R G      Q G 
Sbjct: 688 NGPHGSVSGQSSGFG---HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSG------- 436
           + G S   G +  G ++ SG    G   GHS    + G   G  +S    GSG       
Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSC 804

Query: 437 --YQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQF 494
             Y+ G  Q     Q     G      G   G     GR G   G      Q+    GQ 
Sbjct: 805 GHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQS 864

Query: 495 EQHFQHGGYQYNHSGFGQGRH 515
             + QH     +H   G+GRH
Sbjct: 865 SSYGQH--ESASHHASGRGRH 883



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 70/238 (29%), Positives = 85/238 (35%), Gaps = 56/238 (23%)

Query: 328 GPQQQTGGRGGG------RGGYEHSS--YGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH 379
           G     G  G G      RG YE  S    G G HE G G+    GY   G G G  +  
Sbjct: 317 GHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSS--GYSKHGSGSGHSSSQ 374

Query: 380 -QGGWTDG-----GSGGGGGYQDGGY--RDSGFQPGGYHGGHSSGGYQGGGYG------- 424
            Q G T G     G  G    Q   Y   +S  +     G HSSG  Q  G+G       
Sbjct: 375 GQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG 434

Query: 425 ----------GFQTSSS----YTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGR 470
                     GF  SSS     +GSGY  G    ++  +    +   G G G   G G  
Sbjct: 435 QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQH 494

Query: 471 GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHG-------GYQYNHSGFGQ------GRH 515
           G R+GQ      RG +     G    + QHG       G+  + SG GQ      GRH
Sbjct: 495 GSRSGQ----SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRH 548



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 66/246 (26%), Positives = 83/246 (33%), Gaps = 60/246 (24%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSY--GGRGGHEQGGGR----GGRGG-------YDHG 369
            Q    G    + G+    G +E +S+   GRG H  G G+    G RG        Y   
Sbjct: 850  QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909

Query: 370  GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTS 429
            G G GR +      +  G   G G++    + SG+   G   GHSS   Q G   G  + 
Sbjct: 910  GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969

Query: 430  SSYTGS--------GYQGGGYQQD-NRYQDG-----------GHHGDRGG---------- 459
            S   GS        G  G G +Q     Q G           G HG   G          
Sbjct: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029

Query: 460  -------------GRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYN 506
                         G G   G G R  R+GQ  G+G  GS + H       H QHG     
Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS----STHGQHGSTSGQ 1085

Query: 507  HSGFGQ 512
             S  GQ
Sbjct: 1086 SSSCGQ 1091



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 62/204 (30%), Positives = 76/204 (37%), Gaps = 26/204 (12%)

Query: 328 GPQQQTG-GR--GGGRGGYEHSSYGGRGGHEQGGGRGGRGG---YDHGGRGGGRGNKHQG 381
           G +Q  G GR   G R    H  +G   GH    G+ G G    Y  G    G G     
Sbjct: 289 GSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGF 348

Query: 382 GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGG 441
           G  + GSG   GY   G         G HG  S      G +G    SSS   S Y  G 
Sbjct: 349 GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG----SSSRQSSSY--GQ 402

Query: 442 YQQDNRYQDG-GHHGDRGG---GRGGRGGRGGRGGRAGQGGGWGGRGSQN--YHQGGQFE 495
           ++  +R+  G G H    G   G G RG   G+   +GQ G   GR S +  Y  G  + 
Sbjct: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462

Query: 496 QHFQH--------GGYQYNHSGFG 511
             F H         GY  + SG G
Sbjct: 463 SGFGHHESSSEHSSGYTQHGSGSG 486



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 59/195 (30%), Positives = 77/195 (39%), Gaps = 18/195 (9%)

Query: 339  GRGGYEHSSYGGRG-GHEQGGGRGGRGG-------YDHGGRGGGRGNKH-QGGWTDGGSG 389
            G G  + S YG +G G  Q  G G RG        Y   G G GR +   Q G   G S 
Sbjct: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESS 2105

Query: 390  GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG----FQTSSSYTGSGYQGGGYQQD 445
            G G ++    + S +   G   GHSSG  Q G   G     +   S +GS  + G +   
Sbjct: 2106 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSG 2165

Query: 446  NRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGGQFEQHFQHGG- 502
            +R   G  HG +G G G    RG  G  +G     G  G GS      G +E    H   
Sbjct: 2166 SRQSSG--HGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 2223

Query: 503  YQYNHSGFGQGRHYT 517
            +  + SG G    Y+
Sbjct: 2224 FGQHESGSGHSSAYS 2238



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 59/194 (30%), Positives = 73/194 (37%), Gaps = 20/194 (10%)

Query: 335  GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY-DHGGRGG--GRGNKH---QGGWTDGGS 388
            G   G G +E SS       + G G G   GY  HG R G   RG +H    G  +  G 
Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161

Query: 389  GGGGGYQDGGYRDSGFQPG-----GYHG---GHSSG-GYQGGGYGGFQTSSSYTG-SGYQ 438
             G G  Q  G+   G   G     G HG   GHSS  G  G G G   +   Y   SG+ 
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221

Query: 439  GGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHF 498
                Q ++       +   G G G    +G  G  +GQ   +   GS      GQ   H 
Sbjct: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST----GQSSSHG 2277

Query: 499  QHGGYQYNHSGFGQ 512
            QHG      S +GQ
Sbjct: 2278 QHGSGSSQSSSYGQ 2291



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 59/195 (30%), Positives = 75/195 (38%), Gaps = 18/195 (9%)

Query: 339  GRGGYEHSSYGGRG-GHEQGGGRGGRGG-------YDHGGRGGGRGNKH-QGGWTDGGSG 389
            G G  + S YG +G G  Q  G G RG        Y   G G GR +   Q G   G S 
Sbjct: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 2575

Query: 390  GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG----FQTSSSYTGSGYQGGGYQQD 445
            G G ++    + S +   G   GHSSG  Q G   G     +   S +GS    G +   
Sbjct: 2576 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 2635

Query: 446  NRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGGQFEQHFQHGG- 502
            +R   G  HG +G G G    RG  G   G     G  G GS      G +E    H   
Sbjct: 2636 SRQSSG--HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSV 2693

Query: 503  YQYNHSGFGQGRHYT 517
            +  + SG G    Y+
Sbjct: 2694 FGQHESGSGHSSAYS 2708



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 70/209 (33%), Positives = 84/209 (40%), Gaps = 37/209 (17%)

Query: 325  RQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGG-RGGYDHGGRGGGRGNKHQGGW 383
            RQ     Q+  RG    G  HSS    G H  G GR   RG Y+        G+    G 
Sbjct: 2644 RQGSGSGQSPSRGRHGSGLGHSS--SHGQHGSGSGRSSSRGPYE-----SRLGHSSVFGQ 2696

Query: 384  TDGGSGGGGGYQDGGYRDSGFQPGGYHG---GHSSGGYQGGGYGGFQTSSSYTGSGYQGG 440
             + GSG    Y   G     F   G HG   G SS   Q G   G   SSSY   G++G 
Sbjct: 2697 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG--QSSSY---GHRGS 2751

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G  Q + Y   G HG  G G+    GR G G  +GQ   +G  GS +    GQ   + QH
Sbjct: 2752 GSSQSSGY---GRHG-AGSGQSLSHGRHGSG--SGQSSSYGQHGSGS----GQSSGYSQH 2801

Query: 501  G------GYQY-----NHSGFGQGRHYTS 518
            G      GY Y     NH G   G ++ S
Sbjct: 2802 GSGSGQDGYSYCKGGSNHDGGSSGSYFLS 2830



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 59/195 (30%), Positives = 75/195 (38%), Gaps = 18/195 (9%)

Query: 339  GRGGYEHSSYGGRG-GHEQGGGRGGRGG-------YDHGGRGGGRGNKH-QGGWTDGGSG 389
            G G  + S YG +G G  Q  G G RG        Y   G G GR +   Q G   G S 
Sbjct: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1165

Query: 390  GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG----FQTSSSYTGSGYQGGGYQQD 445
            G G ++    + S +   G   GHSSG  Q G   G     +   S +GS    G +   
Sbjct: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 1225

Query: 446  NRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGGQFEQHFQHGG- 502
            +R   G  HG +G G G    RG  G   G     G  G GS      G +E    H   
Sbjct: 1226 SRQSSG--HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 1283

Query: 503  YQYNHSGFGQGRHYT 517
            +  + SG G    Y+
Sbjct: 1284 FGQHESGSGHSSAYS 1298



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 69/214 (32%), Positives = 78/214 (36%), Gaps = 31/214 (14%)

Query: 325  RQDGPQQQTGGRGG-GRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH---- 379
            RQ     Q+ G G  G G  +  SYG  G    G GR    G    G G   G  H    
Sbjct: 1587 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGS---GSGRSSSSGQHGSGLGESSGFGHHESS 1643

Query: 380  ---QGGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
                  ++  GSG G   GY   G R      G  HG  S    + G +G     SS  G
Sbjct: 1644 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSS--G 1701

Query: 435  SGYQGGGYQQD---NRYQDG-GH---HGDRGGGRGGRGGRGGRGGRAGQGGGWG----GR 483
             G QG G  Q     R+  G GH   HG  G G G    RG    R+G    +G    G 
Sbjct: 1702 HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS 1761

Query: 484  G-SQNYHQGGQFEQHF----QHGGYQYNHSGFGQ 512
            G S  Y Q G    HF    QHG      S F Q
Sbjct: 1762 GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 1795



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 62/207 (29%), Positives = 76/207 (36%), Gaps = 26/207 (12%)

Query: 328  GPQQQTGGRGGGRG-----GYEHSSYGGRGGHEQ-GGGRGGRGGY-DHGGRGG--GRGNK 378
            G    +G  G G G     G+  SS G    + Q G G G   GY  HG R G   RG +
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678

Query: 379  HQGGWTDG---GSGGGGGYQDGGYRDSGFQPG-----GYHG---GHSSG-GYQGGGYGGF 426
            H          G  G G  Q  G+   G   G     G HG   GHSS  G  G G G  
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738

Query: 427  QTSSSYTG-SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGS 485
             +   Y   SG+     Q ++       +   G G G    +G  G  +GQ   +   GS
Sbjct: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798

Query: 486  QNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
                  GQ   H QHG      S +GQ
Sbjct: 1799 ST----GQSSSHGQHGSGSSQSSSYGQ 1821



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 64/221 (28%), Positives = 79/221 (35%), Gaps = 41/221 (18%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK---- 378
            Q+     Q  + GR G   G+  SSYG     + G G G        G G G+ +     
Sbjct: 1821 QQGSGSGQSPSRGRHGSGSGHS-SSYG-----QHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874

Query: 379  -----HQGGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGG----------HSSGGYQGG 421
                    G+T  GSG G    Y+  G R      G  HG           H SG  Q  
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934

Query: 422  GYGGFQTSSSYTGS---GYQGGGYQQDNRY----QDGGHHGDRG---GGRGGRGGRGGRG 471
            G+G   + S  + S   G  G G  Q + Y       G    RG    G G   G G R 
Sbjct: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRE 1994

Query: 472  GRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
             R+GQ  G+G  GS + H       H QHG      S  GQ
Sbjct: 1995 SRSGQSSGYGQHGSSSGHS----STHGQHGSASGQSSSCGQ 2031



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 65/215 (30%), Positives = 79/215 (36%), Gaps = 31/215 (14%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY--DHGGRGGGRGNKHQGGWTD 385
            GP +   G   G G  E  S G   G+ Q G   G       HG   G   +  Q G + 
Sbjct: 2448 GPYESGSGHSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS 2506

Query: 386  G-----GSGGGGGYQDGGY----RDSGFQPGGYHGGHSSG-------GYQGGGYGGFQTS 429
            G     G  G G  Q  GY      SG  PG  HG   SG       G  G G  G  +S
Sbjct: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG--HGQRGSGSRQSPSYGRHGSG-SGRSSS 2563

Query: 430  SSYTGSGY---QGGGYQQDNRYQDGGH--HGDRGGGRGGRGGRGGRGGRAGQGGGWGGRG 484
            S   GSG     G G+ + +  Q   +  HG   G   G G  G R G++ +G   G   
Sbjct: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 2623

Query: 485  SQNYHQGGQFEQHFQHGGYQYNHSGFGQ----GRH 515
              + H G       Q  G+    SG GQ    GRH
Sbjct: 2624 GSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 2658



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 61/197 (30%), Positives = 77/197 (39%), Gaps = 22/197 (11%)

Query: 339  GRGGYEHSSYGGRG-GHEQGGGRGGRGG-------YDHGGRGGGRGNKH-QGGWTDGGSG 389
            G G  + S YG +G G  Q  G G RG        Y   G G GR +   Q G   G S 
Sbjct: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1635

Query: 390  GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQT------SSSYTGSGYQGGGYQ 443
            G G ++    + S +   G   GHSSG  Q G   G  +      SSS + S Y  G + 
Sbjct: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY--GQHG 1693

Query: 444  QDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGGQFEQHFQHG 501
              +R   G  HG +G G G    RG  G   G     G  G GS      G +E    H 
Sbjct: 1694 SGSRQSSG--HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1751

Query: 502  G-YQYNHSGFGQGRHYT 517
              +  + SG G    Y+
Sbjct: 1752 SVFGQHESGSGHSSAYS 1768



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 65/206 (31%), Positives = 83/206 (40%), Gaps = 32/206 (15%)

Query: 339  GRGGYEHSSYGGRG---GHEQGGGRGGRGG---YDHGGRGGGRGNKHQGGWTDGGSGGGG 392
            G G  + SSYG +G   G     GR G G      +G  G G G     G    GSG   
Sbjct: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1869

Query: 393  GYQDGGYRDSGFQPGGY--HG---GHSSGGYQGGGYGGFQTSSSYTGS--------GYQG 439
            G+  G +  S +Q  GY  HG   GHSS   Q G   G  +     GS        G  G
Sbjct: 1870 GF--GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG 1927

Query: 440  GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGGQFEQH 497
             G +Q   +   G HG  G G+     RG  G  +GQ   +G  G GS      G +E  
Sbjct: 1928 SGSRQSLGH---GQHGS-GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG 1983

Query: 498  FQHG---GYQYNHSG--FGQGRHYTS 518
              H    G++ + SG   G G+H +S
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSS 2009



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 63/208 (30%), Positives = 76/208 (36%), Gaps = 24/208 (11%)

Query: 328  GPQQQTG-GRGGGRGGYEHSS--YGGRGGHEQGGGRGGRGGYDHGGRG---GGRGNKHQG 381
            G +Q +G GR G   G+  S   +G   GH    G+ G G      RG      G+    
Sbjct: 2165 GSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 2224

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHG---GHSSGGYQGGGYGGFQTSSSYTGSGYQ 438
            G  + GSG    Y   G     F   G HG   G SS   Q G   G Q+SS     G  
Sbjct: 2225 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG-QSSS----HGQH 2279

Query: 439  GGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG---GRAGQGGGW---GGRGSQNYHQGG 492
            G G  Q + Y   G    +   RG  G   G     G+ G G GW    GR      Q  
Sbjct: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 2339

Query: 493  QFEQH----FQHGGYQYNHSGFGQGRHY 516
             F  H    +Q  GY  + SG G    Y
Sbjct: 2340 GFGHHESSSWQSSGYTQHGSGSGHSSSY 2367



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 69/214 (32%), Positives = 76/214 (35%), Gaps = 31/214 (14%)

Query: 325  RQDGPQQQTGGRGG-GRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH---- 379
            RQ     Q+ G G  G G  +  SYG  G    G GR    G    G G   G  H    
Sbjct: 2527 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGS---GSGRSSSSGQHGSGLGESSGFGHHESS 2583

Query: 380  ---QGGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
                  ++  GSG G   GY   G R      G  HG  S      G +G     SS  G
Sbjct: 2584 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS--G 2641

Query: 435  SGYQGGGYQQD---NRYQDG-GH---HGDRGGGRGGRGGRGGRGGRAGQGGGWG----GR 483
             G QG G  Q     R+  G GH   HG  G G G    RG    R G    +G    G 
Sbjct: 2642 HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGS 2701

Query: 484  G-SQNYHQGGQFEQHF----QHGGYQYNHSGFGQ 512
            G S  Y Q G    HF    QHG      S F Q
Sbjct: 2702 GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2735



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 62/218 (28%), Positives = 77/218 (35%), Gaps = 32/218 (14%)

Query: 330  QQQTGGRGGGRGGYEHSSYGGRG-------GHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
            Q   G R G   G   SSYG  G       GH Q G   G+      GR G  G+     
Sbjct: 1436 QSSRGERHGSSSG-SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS-GSGQSSS 1493

Query: 383  WTDGGSGGG-----GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGS-- 435
            ++  GSG G     G Y+ G    SG        G SSG  Q G   G  ++    GS  
Sbjct: 1494 YSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553

Query: 436  GYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQ----- 490
            G      Q          HG  G G     G G +G  +GQ  G G RGS +        
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613

Query: 491  ----GGQFEQHFQHG-------GYQYNHSGFGQGRHYT 517
                 G+     QHG       G+ ++ S  GQ   Y+
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 57/186 (30%), Positives = 73/186 (39%), Gaps = 21/186 (11%)

Query: 339 GRGGYEHSSYGGRG---GHEQGGGR-GGRGGYD--HGGRGGGRGNKHQGGWTDGGSG--G 390
           G G ++ S +G +G   GH     R G   G+   HG  G G       G  + GSG   
Sbjct: 756 GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQAS 815

Query: 391 GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
           G G  + G      Q G   G  SS G  G   G   +S  +  S  Q   Y Q   ++ 
Sbjct: 816 GFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQ---HES 872

Query: 451 GGHHGDRGGGRGGRG-----GRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQY 505
             HH   G GR G G     G G RG  +GQ   +G  GS +    G+     +HG    
Sbjct: 873 ASHHAS-GRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS----GRSSSSGRHGSGSG 927

Query: 506 NHSGFG 511
             SGFG
Sbjct: 928 QSSGFG 933



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 63/211 (29%), Positives = 74/211 (35%), Gaps = 30/211 (14%)

Query: 331  QQTGGRGGGRGGYE-HSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSG 389
            +Q G R G     E H S  G        G G R    HG  G G G          GSG
Sbjct: 958  EQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG 1017

Query: 390  GG-----GGYQDGGYRDSGFQPGGYHGGHSSG-------GYQGGGYGGFQTSSSYTGSGY 437
             G     G Y+ G    S   P     GHSSG         Q  GYG   +SS ++ +  
Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077

Query: 438  QGGGY--QQDNRYQDG------GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYH 489
            Q G    Q  +  Q G        HG  G G     G G +G  +GQ  G G RGS +  
Sbjct: 1078 QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 1137

Query: 490  Q---------GGQFEQHFQHGGYQYNHSGFG 511
                       G+     QHG      SGFG
Sbjct: 1138 SPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 66/212 (31%), Positives = 75/212 (35%), Gaps = 27/212 (12%)

Query: 325  RQDGPQQQTGGRGG-GRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH---- 379
            RQ     Q+ G G  G G  +  SYG  G    G GR    G    G G   G  H    
Sbjct: 1117 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGS---GSGRSSSSGQHGSGLGESSGFGHHESS 1173

Query: 380  ---QGGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
                  ++  GSG G   GY   G R      G  HG  S      G +G     SS  G
Sbjct: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 1233

Query: 435  SGYQGGGYQQD-NRYQDG-GH---HGDRGGGRGGRGGRGGRGGRAGQGGGWG----GRG- 484
                G G+     R+  G GH   HG  G G G    RG    R+G    +G    G G 
Sbjct: 1234 RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293

Query: 485  SQNYHQGGQFEQHF----QHGGYQYNHSGFGQ 512
            S  Y Q G    HF    QHG      S F Q
Sbjct: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 1325



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 61/213 (28%), Positives = 78/213 (36%), Gaps = 39/213 (18%)

Query: 328 GPQQQTG-GRGGGRGGYEHSS--YGGRGGHEQGGGRGGRGGYDHGGRGGGR-GNKHQGGW 383
           G  Q +G GR G   G+  S   +G   GH    G+ G G       G    G+    G+
Sbjct: 758 GSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF 817

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGG----------HSSGGYQGGGYGGFQTSSSYT 433
               SG G GY   G     F   G HG           H S   Q   YG  +++S + 
Sbjct: 818 GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHA 877

Query: 434 --------------GSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGG 479
                         G G +G G  Q   Y   G HG  G GR    GR G G  +GQ  G
Sbjct: 878 SGRGRHGSGSGQSPGHGQRGSGSGQSPSY---GRHGS-GSGRSSSSGRHGSG--SGQSSG 931

Query: 480 WGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
           +G + S      GQ   + QHG    + S + Q
Sbjct: 932 FGHKSS-----SGQSSGYTQHGSGSGHSSSYEQ 959



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 64/206 (31%), Positives = 74/206 (35%), Gaps = 26/206 (12%)

Query: 325  RQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGG-RGGYDHGGRGGGRGNKHQGGW 383
            RQ     Q+  RG    G  HSS    G H  G GR   RG Y+        G+    G 
Sbjct: 1704 RQGSGSGQSPSRGRHGSGLGHSS--SHGQHGSGSGRSSSRGPYESRS-----GHSSVFGQ 1756

Query: 384  TDGGSGGGGGYQDGGYRDSGFQPGGYHG---GHSSGGYQGGGYGGFQTSSSYTGSGYQGG 440
             + GSG    Y   G     F   G HG   G SS   Q G   G Q+SS     G  G 
Sbjct: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG-QSSS----HGQHGS 1811

Query: 441  GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG---GRAGQGGGW---GGRGSQNYHQGGQF 494
            G  Q + Y   G    +   RG  G   G     G+ G G GW    GR      Q   F
Sbjct: 1812 GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1871

Query: 495  EQH----FQHGGYQYNHSGFGQGRHY 516
              H    +Q  GY  + SG G    Y
Sbjct: 1872 GHHESSSWQSSGYTQHGSGSGHSSSY 1897



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 66/212 (31%), Positives = 76/212 (35%), Gaps = 27/212 (12%)

Query: 325  RQDGPQQQTGGRGG-GRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH---- 379
            RQ     Q+ G G  G G  +  SYG  G    G GR    G    G G   G  H    
Sbjct: 2057 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGS---GSGRSSSSGQHGPGLGESSGFGHHESS 2113

Query: 380  ---QGGWTDGGSGGG--GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
                  ++  GSG G   GY   G R      G  HG  S    + G +G     SS  G
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173

Query: 435  SGYQGGGYQQD-NRYQDG-GH---HGDRGGGRGGRGGRGGRGGRAGQGGGWG----GRG- 484
                G G+     R+  G GH   HG  G G G    RG    R+G    +G    G G 
Sbjct: 2174 RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233

Query: 485  SQNYHQGGQFEQHF----QHGGYQYNHSGFGQ 512
            S  Y Q G    HF    QHG      S F Q
Sbjct: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 67/212 (31%), Positives = 81/212 (38%), Gaps = 32/212 (15%)

Query: 328  GPQQQTG-GRGGGRGGYEHSS--YGGRGGHEQGGGRGGRGGYDHGGRG---GGRGNKHQG 381
            G +Q +G GR G   G+  S   +G   GH    G+ G G      RG      G+    
Sbjct: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284

Query: 382  GWTDGGSGGGGGYQDGGYRDSGFQPGGYHG---GHSSGGYQGGGYGGFQTSSSYTGSGYQ 438
            G  + GSG    Y   G     F   G HG   G SS   Q G   G   SSSY   G++
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG--QSSSY---GHR 1339

Query: 439  GGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG-------GRAGQGGGW---GGRGSQNY 488
            G G  Q + Y   G HG  G G+    GR G G       G+ G G GW    GR     
Sbjct: 1340 GSGSSQSSGY---GRHG-AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1395

Query: 489  HQGGQFEQH----FQHGGYQYNHSGFGQGRHY 516
             Q   F  H    +Q  G   + SG G    Y
Sbjct: 1396 GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSY 1427



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 59/198 (29%), Positives = 74/198 (37%), Gaps = 22/198 (11%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            G    T G+    G +  SS       + G G     GY   G G G+   H       G
Sbjct: 1547 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-------G 1599

Query: 388  SGGGGGYQDGGY--RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQ-GGGYQQ 444
              G G  Q   Y    SG       G H SG  +  G+G  ++SS  + S  Q G G   
Sbjct: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659

Query: 445  DNRYQDGGHHGDRGG--GRGGRGGRGGRGG-RAGQGGGWGGRGSQNYHQG---GQFEQHF 498
             + Y   G HG R G   RG R G   R   R GQ G    + S +  QG   GQ     
Sbjct: 1660 SSGY---GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRG 1716

Query: 499  QHG---GYQYNHSGFGQG 513
            +HG   G+  +H   G G
Sbjct: 1717 RHGSGLGHSSSHGQHGSG 1734



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 63/211 (29%), Positives = 83/211 (39%), Gaps = 27/211 (12%)

Query: 325  RQDGPQQQTG-GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGG 382
            R  G  Q +G GR G   G   S    RG H  G G G    Y  HG   G   +  + G
Sbjct: 1339 RGSGSSQSSGYGRHGAGSGQSPS----RGRH--GSGSGHSSSYGQHGSGSGWSSSSGRHG 1392

Query: 383  WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG--------FQTSSSYTG 434
               G S G G ++   ++ SG    G   GHSS   Q G   G          +S S + 
Sbjct: 1393 SGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 1452

Query: 435  SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWG--GRGSQNYHQGG 492
             G  G G +Q   +   G HG  G G+     RG  G  +GQ   +   G GS      G
Sbjct: 1453 YGQHGSGSRQSLGH---GQHGS-GSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508

Query: 493  QFEQHFQHG---GYQYNHSG--FGQGRHYTS 518
             +E    H    G++ + SG   G G+H +S
Sbjct: 1509 PYESGSSHSSGLGHRESRSGQSSGYGQHGSS 1539



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 67/217 (30%), Positives = 81/217 (37%), Gaps = 35/217 (16%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY--DHGGRGGGRGNKHQGGWTD 385
            GP +       G G  E  S G   G+ Q G   G       HG   G   +  Q G + 
Sbjct: 1508 GPYESGSSHSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS 1566

Query: 386  G-----GSGGGGGYQDGGY----RDSGFQPGGYHGGHSSG-------GYQGGGYGGFQTS 429
            G     G  G G  Q  GY      SG  PG  HG   SG       G  G G  G  +S
Sbjct: 1567 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG--HGQRGSGSRQSPSYGRHGSG-SGRSSS 1623

Query: 430  SSYTGSGY---QGGGYQQDNRYQDGGH--HGDRGGGRGGRGGRGGRGGRAGQG--GGWGG 482
            S   GSG     G G+ + +  Q   +  HG   G   G G  G R G++ +G   G   
Sbjct: 1624 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 1683

Query: 483  RGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ----GRH 515
            R S  Y Q G   +  Q  G+    SG GQ    GRH
Sbjct: 1684 RSSSRYGQHGSGSR--QSSGHGRQGSGSGQSPSRGRH 1718



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 65/226 (28%), Positives = 74/226 (32%), Gaps = 35/226 (15%)

Query: 323 QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH--- 379
           Q    GP     GR   RG YE  S    G   Q    G   GY   G   G  + H   
Sbjct: 554 QSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH 613

Query: 380 -----------QGGWTDG-----GSGGGGGYQDGGYRDSGFQPG-----GYHG---GHSS 415
                      Q G T G     G  G G  Q   Y   G   G     G HG   GHSS
Sbjct: 614 GSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSS 673

Query: 416 GGYQGGGYGGFQTSSSYTGS--GYQGG-----GYQQDNRYQDGGHHGDRGGGRGGRGGRG 468
              Q G   G+ +S+   GS  G   G     G  Q + Y   G       G    G R 
Sbjct: 674 SYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRS 733

Query: 469 GRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
           G+  R+ Q G   G  S +Y Q G         G Q + SG    R
Sbjct: 734 GQSSRSEQHGSSSGL-SSSYGQHGSGSHQSSGHGRQGSGSGHSPSR 778



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 52/206 (25%), Positives = 71/206 (34%), Gaps = 14/206 (6%)

Query: 322 WQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQG 381
           +Q+   G      G+    G     S+   G  + G G G    Y   G G G+ + +  
Sbjct: 161 FQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDT 220

Query: 382 -GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSG-GYQGGGYGGFQTSSSYTGSGYQG 439
            G   G S G   ++    + SG+   G   GHSSG G  G   G       +  S    
Sbjct: 221 HGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSS 280

Query: 440 GGYQQDNRYQDGGHHGDRGGGRGGRGGR--------GGRGGRAGQGGGWGGRGSQNYHQG 491
             Y Q       G     G GR G G R        G   G +   G  G   S +Y +G
Sbjct: 281 SSYGQ----HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG 336

Query: 492 GQFEQHFQHGGYQYNHSGFGQGRHYT 517
                  Q  G+  + SG GQ   Y+
Sbjct: 337 HYESGSGQTSGFGQHESGSGQSSGYS 362



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 66/207 (31%), Positives = 79/207 (38%), Gaps = 37/207 (17%)

Query: 335 GRGGGRGGYEHSSYGGR--GGHEQGGGRGGRGGY-DHGGRGG--GRGNKHQGG------W 383
           G G   G  +H S  G+  G  + G G G   GY  HG R G   RG +H+        +
Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY 283

Query: 384 TDGGSGG----GGGYQDGGYRDS------GFQPG-----GYHGGHSSGGYQGGGY--GGF 426
              GSG     G G Q  G R S      G   G     G HG  SS  Y  G Y  G  
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343

Query: 427 QTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQ 486
           QTS    G G    G  Q + Y   G        +G  G   G+   +GQ G    R S 
Sbjct: 344 QTS----GFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS-SSRQSS 398

Query: 487 NYHQGGQFEQHFQHGGYQYNH-SGFGQ 512
           +Y   GQ E   +H   +  H SG GQ
Sbjct: 399 SY---GQHESASRHSSGRGQHSSGSGQ 422



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/188 (28%), Positives = 63/188 (33%), Gaps = 15/188 (7%)

Query: 330  QQQTGGRGGGRGGY--EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            Q Q G   G    +  E SS G    H Q G  G      +G +G G G     G    G
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-GSSQSSSYGQQGSGSGQSPSRGRHGSG 2308

Query: 388  SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNR 447
            SG    Y          Q G   G  SS G  G G G       +  S +Q  GY Q   
Sbjct: 2309 SGHSSSYG---------QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQ--- 2356

Query: 448  YQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNH 507
            +  G  H       G R G+  RG R G   G      Q+     Q   H QHG      
Sbjct: 2357 HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 2416

Query: 508  SGFGQGRH 515
                +GRH
Sbjct: 2417 PSPSRGRH 2424



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 61/235 (25%), Positives = 78/235 (33%), Gaps = 50/235 (21%)

Query: 323 QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           Q    G  +       GRG +   S    G  ++G G G        G G GR +   G 
Sbjct: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSS-SGP 454

Query: 383 WTDGG--SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGS----- 435
           +  G   S G G ++      SG+   G   GHSSG  Q G   G  +     GS     
Sbjct: 455 YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514

Query: 436 ---GYQGGGYQQD------------------NRYQDG-------GHHGDRGG-------- 459
              G  G G +Q                    R++ G       G HG   G        
Sbjct: 515 SSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPY 574

Query: 460 --GRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
             G G   G G +  R+GQ  G+G  GS + H       H QHG      S  GQ
Sbjct: 575 ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHS----STHGQHGSTSGQSSSCGQ 625



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 55/199 (27%), Positives = 68/199 (34%), Gaps = 20/199 (10%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            G    T G+    G +  SS       + G G     GY   G G G+   H       G
Sbjct: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-------G 1129

Query: 388  SGGGGGYQDGGY--RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGG----- 440
              G G  Q   Y    SG       G H SG  +  G+G  ++SS  + S  Q G     
Sbjct: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1189

Query: 441  --GYQQDNRYQDGGHHGDRGGGRGGRG---GRGGRGGRAGQGGGWGGRGSQNYHQGGQFE 495
              GY Q          G+R G   G     G+ G G R   G G  G GS +    G+  
Sbjct: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249

Query: 496  QHFQHGGYQYNHSGFGQGR 514
                H      H G G GR
Sbjct: 1250 SGLGHSSSHGQH-GSGSGR 1267



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 56/201 (27%), Positives = 70/201 (34%), Gaps = 28/201 (13%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            G    T G+    G +  SS       + G G     GY   G G G+   H       G
Sbjct: 2487 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-------G 2539

Query: 388  SGGGGGYQDGGY--RDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGG----- 440
              G G  Q   Y    SG       G H SG  +  G+G  ++SS  + S  Q G     
Sbjct: 2540 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 2599

Query: 441  --GYQQDNRYQDGGHHGDRGGGRGGRG---GRGGRGGRAGQGGGWGGRGSQNYHQGGQFE 495
              GY Q          G+R G   G     G+ G G R   G G  G GS      GQ  
Sbjct: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS------GQSP 2653

Query: 496  QHFQHG---GYQYNHSGFGQG 513
               +HG   G+  +H   G G
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSG 2674



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 56/207 (27%), Positives = 72/207 (34%), Gaps = 29/207 (14%)

Query: 324 KRQDGPQQQTGGRGGGRGGYEHSSYGGRG--GHEQGGGRGGRGGYDHGGRGGGRG---NK 378
           +   G  Q   G G   G  +H S  G+   G  QG   G    Y   G G  +    ++
Sbjct: 473 EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSR 532

Query: 379 HQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSS--GGYQGG-GYG---GFQTSSSY 432
           H  G     S   G ++ G  + S + P GY  G SS  G Y+ G G+    G Q S S 
Sbjct: 533 HGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSG 592

Query: 433 TGSGYQGGGYQQDNRYQDGGH------------HGDRGG---GRGGRGGRGGRGGRAGQG 477
             SGY   G    +    G H            HG   G     G  G    +  R GQ 
Sbjct: 593 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQ 652

Query: 478 GGWGGRGSQNYHQGGQF---EQHFQHG 501
           G   G+       G  F     + QHG
Sbjct: 653 GSGSGQSPSRGRHGSDFGHSSSYGQHG 679



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 52/194 (26%), Positives = 70/194 (36%), Gaps = 8/194 (4%)

Query: 326  QDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRG-GGRGNKHQGGWT 384
            Q     Q G   G    Y H   G       G GR G G      RG  G G+ H   + 
Sbjct: 1319 QSSTFDQEGSSTGQSSSYGHR--GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376

Query: 385  DGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQ 444
              GSG G     G +     Q  G+ G H S  +Q  G     + S ++ S  Q G   +
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGF-GHHESSSWQSSGCTQHGSGSGHSSSYEQHG--SR 1433

Query: 445  DNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQ 504
              +   G  HG   G      G+ G G R   G G  G GS       +  +H    G  
Sbjct: 1434 SGQSSRGERHGSSSGSSSSY-GQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQS 1491

Query: 505  YNHSGFGQGRHYTS 518
             ++S +G G  ++S
Sbjct: 1492 SSYSPYGSGSGWSS 1505



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 53/188 (28%), Positives = 63/188 (33%), Gaps = 15/188 (7%)

Query: 330  QQQTGGRGGGRGGY--EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            Q Q G   G    +  E SS G    H Q G  G      +G +G G G     G    G
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-GSSQSSSYGQQGSGSGQSPSRGRHGSG 1838

Query: 388  SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNR 447
            SG    Y          Q G   G  SS G  G G G       +  S +Q  GY Q   
Sbjct: 1839 SGHSSSYG---------QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQ--- 1886

Query: 448  YQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNH 507
            +  G  H       G R G+  RG + G   G      Q+     Q   H QHG      
Sbjct: 1887 HGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1946

Query: 508  SGFGQGRH 515
                +GRH
Sbjct: 1947 PSPSRGRH 1954



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 63/220 (28%), Positives = 78/220 (35%), Gaps = 40/220 (18%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY--DHGGRGG--------GRGN 377
            G ++   G+  G G +  SS G    H Q G   G+      HG   G        G G+
Sbjct: 1991 GHRESRSGQSSGYGQHGSSS-GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGS 2049

Query: 378  KHQGGWTDGGSGGGGGYQDG-GYRDSGFQPGGYHGGHSSG-------GYQGGGYG----- 424
                G+  G  G G G   G G R SG +    +G H SG       G  G G G     
Sbjct: 2050 SQSSGY--GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107

Query: 425  GFQTSSSYTGSGYQ--------GGGYQQDNRYQDGGHHGDRGG---GRGGRGGRGGRGGR 473
            G   SSS   S Y           GY Q          G+R G   G   R G+ G G R
Sbjct: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167

Query: 474  AGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQG 513
               G G  G GS +    G   +H    G+  +H   G G
Sbjct: 2168 QSSGHGRQGSGSGHSPSRG---RHGSGSGHSSSHGQHGSG 2204



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 57/208 (27%), Positives = 75/208 (36%), Gaps = 29/208 (13%)

Query: 333 TGGRGGGRGGYEHS--SYGGRGGHEQGGGRGGRGGYD---HGGRGGGRGNK--------- 378
           T G+ G   G   S   +G   G     G+ G G      +G +G G G           
Sbjct: 609 THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSD 668

Query: 379 --HQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSG 436
             H   +   GSG G    +G +     Q  G+  GH SG  Q  GY    + SS++ SG
Sbjct: 669 FGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGF--GHKSGSGQSSGYSQHGSGSSHS-SG 725

Query: 437 YQGGGYQQDNRYQDGGHHGDRGG-----GRGGRGGRGGRG-GRAGQGGGWGGRGSQNYHQ 490
           Y+  G  +  +      HG   G     G+ G G     G GR G G G      ++   
Sbjct: 726 YRKHG-SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784

Query: 491 GGQFEQHFQHGGYQYNHSGFGQGRHYTS 518
            G    H QHG      S  G   HY S
Sbjct: 785 SGHSSSHGQHGSGTSCSSSCG---HYES 809



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 51/187 (27%), Positives = 68/187 (36%), Gaps = 11/187 (5%)

Query: 337  GGGRGGY----EHSSYGGRGG--HEQGGGRGGRGGYDHGGRGGGRGNKH-QGGWTDGGSG 389
            G G G +    +H S  G+     ++G   G    Y H G G  + + + + G   G S 
Sbjct: 1301 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSP 1360

Query: 390  GGGGYQDG-GYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRY 448
              G +  G G+  S  Q G   G  SS G  G G G       +  S +Q  G  Q   +
Sbjct: 1361 SRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQ---H 1417

Query: 449  QDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHS 508
              G  H       G R G+  RG R G   G      Q+     Q   H QHG       
Sbjct: 1418 GSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1477

Query: 509  GFGQGRH 515
               +GRH
Sbjct: 1478 SPSRGRH 1484



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 56/208 (26%), Positives = 74/208 (35%), Gaps = 31/208 (14%)

Query: 335  GRGGGRGGYEHSS--------YGGRGGHEQG----GGRGGRG--GYDHGGRGG------- 373
            G   G G +E SS        +G   GH  G    G R G+   G  HG   G       
Sbjct: 1162 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ 1221

Query: 374  -GRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSY 432
             G G++   G    GSG G      G   SG      HG H SG  +    G +++ S +
Sbjct: 1222 HGSGSRQSSGHGRQGSGSGHS-PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH 1280

Query: 433  TG-SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQG 491
            +   G    G    + Y   G        +G  G   G+     Q G   G+ S   H+G
Sbjct: 1281 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG 1340

Query: 492  GQFEQHFQHGGYQYNHSGFGQ----GRH 515
                   Q  GY  + +G GQ    GRH
Sbjct: 1341 SGSS---QSSGYGRHGAGSGQSPSRGRH 1365



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 52/189 (27%), Positives = 67/189 (35%), Gaps = 21/189 (11%)

Query: 328  GPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGW 383
            G      GR   RG YE    HSS  G+  HE G G        +   G G G+    G 
Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQ--HESGSGHSSA----YSQHGSGSGHFCSQGQ 1782

Query: 384  TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGS-GYQGGGY 442
                SG    +   G         G HG   SG  Q   YG   + S  + S G  G G 
Sbjct: 1783 HGSTSGQSSTFDQEGSSTGQSSSHGQHG---SGSSQSSSYGQQGSGSGQSPSRGRHGSGS 1839

Query: 443  QQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGG 502
               + Y      G  G G G     G  G  +GQ  G+G   S ++   G + QH    G
Sbjct: 1840 GHSSSY------GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG-YTQHGSGSG 1892

Query: 503  YQYNHSGFG 511
            +  ++   G
Sbjct: 1893 HSSSYEQHG 1901



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 52/189 (27%), Positives = 67/189 (35%), Gaps = 21/189 (11%)

Query: 328  GPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGW 383
            G      GR   RG YE    HSS  G+  HE G G        +   G G G+    G 
Sbjct: 2199 GQHGSGSGRSSSRGPYESRSGHSSVFGQ--HESGSGHSSA----YSQHGSGSGHFCSQGQ 2252

Query: 384  TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGS-GYQGGGY 442
                SG    +   G         G HG   SG  Q   YG   + S  + S G  G G 
Sbjct: 2253 HGSTSGQSSTFDQEGSSTGQSSSHGQHG---SGSSQSSSYGQQGSGSGQSPSRGRHGSGS 2309

Query: 443  QQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGG 502
               + Y      G  G G G     G  G  +GQ  G+G   S ++   G + QH    G
Sbjct: 2310 GHSSSY------GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG-YTQHGSGSG 2362

Query: 503  YQYNHSGFG 511
            +  ++   G
Sbjct: 2363 HSSSYEQHG 2371



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 55/214 (25%), Positives = 74/214 (34%), Gaps = 31/214 (14%)

Query: 326  QDGPQQQTG-GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
            + G  Q +G G+     G  +S +G   GH    GR       HG   G   +  Q   +
Sbjct: 808  ESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSGQHDSS 860

Query: 385  DGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSG--------------GYQGGGYGGFQTSS 430
             G S   G ++   +  SG    G   G S G              G  G G G   +S 
Sbjct: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSG 920

Query: 431  SY-TGSGYQGGGYQQDNRYQDGGH--HGDRGGGRGG---RGGRGGRGGRAGQGGGWGGRG 484
             + +GSG   G   + +  Q  G+  HG   G        G R G+  R+ Q G   G  
Sbjct: 921  RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSS 980

Query: 485  SQNYHQGGQFEQ---HFQHGGYQYNHSGFGQGRH 515
            S     G    Q   H QHG          +GRH
Sbjct: 981  SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1014



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 40/124 (32%), Positives = 47/124 (37%), Gaps = 13/124 (10%)

Query: 330  QQQTGGRGGGRGGYEHSSYGGRGG---HEQGGGRGGRG---GYDHGGRGGGRGNKHQGGW 383
            Q  T  + G   G + SSYG RG       G GR G G      HG  G G G     G 
Sbjct: 2729 QSSTFDQEGSSTG-QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQ 2787

Query: 384  TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQ 443
               GSG   GY   G   SG    GY        + GG  G +  S   + S Y+   Y 
Sbjct: 2788 HGSGSGQSSGYSQHG---SGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYE---YV 2841

Query: 444  QDNR 447
            Q+ R
Sbjct: 2842 QEQR 2845


>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
           [Homo sapiens]
          Length = 320

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 60/131 (45%), Positives = 70/131 (53%), Gaps = 23/131 (17%)

Query: 323 QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           Q+ + G     GGRGGG GG ++    GRGG+    GRGG GG   GG  GG G+ + G 
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNF---GRGGNF--SGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 383 WTDGGS-GGGGGYQD-GGY--RDSGFQP--GGYHGGHSSGGYQG-----------GGYGG 425
             DG + GGGG Y D G Y  + S F P  GG  GG SSG Y G           GGYGG
Sbjct: 248 GNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGG 307

Query: 426 FQTSSSYTGSG 436
             +SSSY GSG
Sbjct: 308 SSSSSSY-GSG 317



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 61/176 (34%), Positives = 75/176 (42%), Gaps = 51/176 (28%)

Query: 346 SSYGGRGGHEQ-GGGRGGR-GGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSG 403
           SS  GR G    GGGRGG  GG D+ GRGG    +  GG+  GGS GGGGY         
Sbjct: 191 SSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGR--GGF--GGSRGGGGY--------- 237

Query: 404 FQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGG 463
                        G  G GY GF       GS + GGG      Y D G++ ++    G 
Sbjct: 238 -------------GGSGDGYNGFGND----GSNFGGGG-----SYNDFGNYNNQSSNFGP 275

Query: 464 RGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ-FEQHFQHGGY--QYNHSGFGQGRHY 516
                       +GG +GGR S  Y  GGQ F +    GGY    + S +G GR +
Sbjct: 276 M-----------KGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF 320



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 443 QQDNRYQDGGHHGDRGGGRGGRGGRGGRGG--RAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
           +Q+         G  G G  G G  GG GG    G+GG + GRG     +GG       +
Sbjct: 183 KQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGG-----GY 237

Query: 501 GGYQYNHSGFG 511
           GG    ++GFG
Sbjct: 238 GGSGDGYNGFG 248


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 69/172 (40%), Positives = 76/172 (44%), Gaps = 52/172 (30%)

Query: 323 QKRQDGPQQQTGGR--------GGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDH------ 368
           Q+   G QQQ+ G+        G G+    +SS GG GG    GG GG  G D       
Sbjct: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG----GGGGGNYGQDQSSMSSG 187

Query: 369 GGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQT 428
           GG GGG GN+ Q G      GG GGY   G +D         GG   GG  GGG GG   
Sbjct: 188 GGSGGGYGNQDQSG-----GGGSGGY---GQQD--------RGGRGRGGSGGGGGGG--- 228

Query: 429 SSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG--RGGRAGQGG 478
                     GGGY   NR   G     RGGGRGGRGG GG  RGG    GG
Sbjct: 229 ----------GGGY---NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 65/190 (34%), Positives = 79/190 (41%), Gaps = 29/190 (15%)

Query: 333 TGGRGGGRGGY----EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGS 388
           TGG G  +       + SSY G G  +Q       G Y    +    G    G ++   S
Sbjct: 78  TGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135

Query: 389 GGGGGYQDGGYRDSGFQPGGY-----HGGHSSGGYQGGGYGGF-QTSSSYTGSGYQGGGY 442
            GG   Q  G + S   P GY     +   S GG  GGG G + Q  SS +  G  GGGY
Sbjct: 136 YGGQ-QQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194

Query: 443 QQDNRYQDGGHHG----DRGG-GRGGRGGRGGRGGRA-----------GQGGGWGGRGSQ 486
              ++   GG  G    DRGG GRGG GG GG GG             G+GGG GGRG  
Sbjct: 195 GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM 254

Query: 487 NYHQGGQFEQ 496
                G F +
Sbjct: 255 GGSDRGGFNK 264



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 56/142 (39%), Positives = 67/142 (47%), Gaps = 18/142 (12%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQGG-GRGGRGGYDHGGRGGGRGNKHQGGW---TDGGSGG 390
           G G GRGG       GRGG+  GG G GGRGG+  GG GGG G +  G W          
Sbjct: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGG-GGGGGQQRAGDWKCPNPTCENM 436

Query: 391 GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
              +++   +    +P G  GG   G + GG YG  +        GY  GGY+       
Sbjct: 437 NFSWRNECNQCKAPKPDG-PGGGPGGSHMGGNYGDDRRGGR---GGYDRGGYR------- 485

Query: 451 GGHHGDRGGGRGGRGGRGGRGG 472
            G  GDRGG RGGRGG G RGG
Sbjct: 486 -GRGGDRGGFRGGRGG-GDRGG 505



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 69/203 (33%), Positives = 83/203 (40%), Gaps = 36/203 (17%)

Query: 321 PWQKRQDGPQQQTGGRGGGRGGYEHSSYGG--RGGHEQGGGRGGR----GGYDHGGRGGG 374
           P   +Q  P   +G  G      + SSYG    G + Q    GG+    G         G
Sbjct: 98  PGYGQQPAPSSTSGSYGSSS---QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154

Query: 375 RGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
            G ++Q   + GG GGGGG  + G   S           SSGG  GGGYG    +   +G
Sbjct: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSM---------SSGGGSGGGYG----NQDQSG 201

Query: 435 SGYQGGGYQQDNRYQDGGHHGDRGGGRGG-----------RGGRGGRGGRAGQGGGWGGR 483
            G  GG  QQD   +  G  G  GGG GG           RG  GGRGGR G GG    R
Sbjct: 202 GGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDR 259

Query: 484 GSQNYHQGGQFEQHFQHGGYQYN 506
           G  N   GG  +Q  +H   Q N
Sbjct: 260 GGFNKF-GGPRDQGSRHDSEQDN 281



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 55/146 (37%), Positives = 61/146 (41%), Gaps = 43/146 (29%)

Query: 335 GRGG--GRGGYEH--SSYGGRGGHEQGGGRGG---RGGY--------------------- 366
           GRGG  GRGGY    S  GGRGG   GGG GG   R G                      
Sbjct: 387 GRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ 446

Query: 367 ----DHGGRGGGRGNKHQGG-WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGG 421
                  G GGG G  H GG + D   GG GGY  GGYR  G   GG+ GG   GG   G
Sbjct: 447 CKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGR--GGGDRG 504

Query: 422 GYGGFQTSSSYTGSGYQGGGYQQDNR 447
           G+G  +  S         G ++QD R
Sbjct: 505 GFGPGKMDSR--------GEHRQDRR 522



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 59/174 (33%), Positives = 71/174 (40%), Gaps = 43/174 (24%)

Query: 340 RGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGY 399
           R  +      GRGG  +GG  G RGGY  GG GGG     +GG+  GG GGGG  + G +
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMG-RGGYGGGGSGGGG----RGGFPSGGGGGGGQQRAGDW 426

Query: 400 RDSGFQPGGYHGGHSSGGYQ---------GGGYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
           +         +    +   Q         GGG GG           + GG Y  D R   
Sbjct: 427 KCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGG----------SHMGGNYGDDRR--- 473

Query: 451 GGHHGDRGGGRGG--RGGRGGRGG-----RAGQGGG-WGGRGSQNYHQGGQFEQ 496
                   GGRGG  RGG  GRGG     R G+GGG  GG G       G+  Q
Sbjct: 474 --------GGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQ 519



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 65/219 (29%), Positives = 83/219 (37%), Gaps = 39/219 (17%)

Query: 320 PPWQKRQDGPQQQTGGRGGGRGGY------EHSSYGGRGGHEQGGGRGGRGGYDHGGRGG 373
           P  Q+   G  Q T   G G+  Y      +++ YG +   +  G  GG G         
Sbjct: 32  PYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY 91

Query: 374 GRGNKHQG-GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGG----------- 421
           G+ + + G G     S   G Y       S  QP    G +S     GG           
Sbjct: 92  GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS--GSYSQQPSYGGQQQSYGQQQSY 149

Query: 422 ----GYG---GFQTSSSYTGSGYQGGGYQQDNRYQ-----DGGHHGDR----GGGRGGRG 465
               GYG    + +SS   G G  GG Y QD          GG +G++    GGG GG G
Sbjct: 150 NPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYG 209

Query: 466 --GRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGG 502
              RGGR GR G GGG GG G       G +E   + GG
Sbjct: 210 QQDRGGR-GRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG 247



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/164 (32%), Positives = 63/164 (38%), Gaps = 30/164 (18%)

Query: 351 RGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYH 410
           RGG   G GRGGRG      RGG  G   +GG+  GGSGGGG          GF  GG  
Sbjct: 377 RGG---GNGRGGRG------RGGPMG---RGGYGGGGSGGGGR--------GGFPSGGGG 416

Query: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGR 470
           GG   G  + G +     +       ++    Q      DG   G  G   GG  G   R
Sbjct: 417 GG---GQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRR 473

Query: 471 GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
           GGR       GG     Y   G     F+ G    +  GFG G+
Sbjct: 474 GGR-------GGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGK 510



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 30/144 (20%)

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTS---SSYTGSGYQGGGYQQDNRY------QDGGHHG 455
           QPG  +   SS  Y    Y G+  S   S Y  S Y   G  Q+  Y      Q  G  G
Sbjct: 20  QPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTG 79

Query: 456 DRGGGRGGRGGRGGRGGRAGQG---------GGWGGRGSQNYH---QGGQFEQHFQHGGY 503
             G  +  +   G +    G G         G +G     + +   Q G + Q   +GG 
Sbjct: 80  GYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQ 139

Query: 504 QYNH---------SGFGQGRHYTS 518
           Q ++          G+GQ   Y S
Sbjct: 140 QQSYGQQQSYNPPQGYGQQNQYNS 163


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 60/146 (41%), Positives = 66/146 (45%), Gaps = 26/146 (17%)

Query: 338 GGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDG 397
           GG GG   SS GGRGG  +GGGR   G      +GGG      GG+   G  GGGG   G
Sbjct: 182 GGGGGGSRSSRGGRGGRGRGGGRDQNGL----SKGGG------GGYNSYGGYGGGG--GG 229

Query: 398 GYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDR 457
           GY   G   GG   G S  G   GG+G +    S  G    GGG         GG  G  
Sbjct: 230 GYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGG---------GGGGGSS 280

Query: 458 GGGRGGRGG-RGGRGGRAGQGGGWGG 482
            GGR   G  RGG GG    GGG+GG
Sbjct: 281 WGGRSNSGPYRGGYGG----GGGYGG 302



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 59/141 (41%), Positives = 64/141 (45%), Gaps = 26/141 (18%)

Query: 348 YGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPG 407
           Y G GG   GG R  RGG    GRGGGR    Q G + GG GG   Y            G
Sbjct: 180 YSGGGG---GGSRSSRGGRGGRGRGGGRD---QNGLSKGGGGGYNSY------------G 221

Query: 408 GYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRY-QDGGHHGDRGGGRGGRGG 466
           GY GG   GGY    YGG    SSY GS Y G G+     Y Q    +G    G GG GG
Sbjct: 222 GYGGG-GGGGYNA--YGGGGGGSSYGGSDY-GNGFGGFGSYSQHQSSYGPMKSGGGGGGG 277

Query: 467 RGGRGGRAGQG---GGWGGRG 484
               GGR+  G   GG+GG G
Sbjct: 278 GSSWGGRSNSGPYRGGYGGGG 298



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 48/107 (44%), Positives = 56/107 (52%), Gaps = 14/107 (13%)

Query: 328 GPQQQTGGRGGGRGGYE-HSSYGGRGG---HEQGGGRGGR--GGYDHGGRGGGRG--NKH 379
           G + Q G   GG GGY  +  YGG GG   +  GGG GG   GG D+G   GG G  ++H
Sbjct: 202 GGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQH 261

Query: 380 Q---GGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGY 423
           Q   G    GG GGGGG   GG  +SG   GGY GG   GGY G  +
Sbjct: 262 QSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGG---GGYGGSSF 305



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 33/83 (39%), Positives = 42/83 (50%), Gaps = 10/83 (12%)

Query: 418 YQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGG-----HHGDRGGGRGGRGGRGGRGG 472
           Y GGG GG ++S    G   +GGG  Q+   + GG     + G  GGG GG    GG GG
Sbjct: 180 YSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGG 239

Query: 473 RAGQGG-----GWGGRGSQNYHQ 490
            +  GG     G+GG GS + HQ
Sbjct: 240 GSSYGGSDYGNGFGGFGSYSQHQ 262



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 22/84 (26%)

Query: 444 QDNRYQDGGHHGDRGGGRGGRGGRGGRGGR------AGQGGGW--------GGRGSQNYH 489
           +++ Y  GG  G R   RGGRGGRG  GGR       G GGG+        GG G  N +
Sbjct: 176 KEDIYSGGGGGGSRSS-RGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAY 234

Query: 490 QGGQFEQHFQHGGYQYNHSGFGQG 513
            GG        GG  Y  S +G G
Sbjct: 235 GGG-------GGGSSYGGSDYGNG 251


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 59/150 (39%), Positives = 68/150 (45%), Gaps = 14/150 (9%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGY 394
           GRGGG GG+   S G       GG R     +    R GG G    GG+  GG G     
Sbjct: 11  GRGGGGGGFRGFSSGS--AVVSGGSRRSTSSFSCLSRHGGGG----GGFGGGGFGSRSLV 64

Query: 395 QDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSY-TGSGYQGGGYQQDNRYQDGGH 453
             GG +       G  GG  + G  GG  GGF   SS+  GSG+ GGG      +  GG 
Sbjct: 65  GLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGG------FGGGGF 118

Query: 454 HGDRGGGRGGRGGRGGRGGRAGQG-GGWGG 482
            G R GG GG GG GG GG  G G GG+ G
Sbjct: 119 GGGRFGGFGGPGGVGGLGGPGGFGPGGYPG 148



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 51/140 (36%), Positives = 60/140 (42%), Gaps = 30/140 (21%)

Query: 346 SSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQ 405
           +++GG GG     G    GGY  G    G G +  G  + GGSGGGG    GGY   G  
Sbjct: 516 AAFGGSGGRGSSSG----GGYSSGSSSYGSGGRQSG--SRGGSGGGGSISGGGYGSGGGS 569

Query: 406 PGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG 465
            G Y  G   GG +GG         S +G GY  G          GG H   GG RGG  
Sbjct: 570 GGRYGSG---GGSKGG---------SISGGGYGSG----------GGKHSSGGGSRGGSS 607

Query: 466 GRGGRGGRAGQGGGWGGRGS 485
             GG G  +G GG    +GS
Sbjct: 608 SGGGYG--SGGGGSSSVKGS 625



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 54/118 (45%), Positives = 59/118 (50%), Gaps = 16/118 (13%)

Query: 333 TGGRGGGRGG--YEHSSYGGRGGHEQG--GGRGGRG-----GYDHGGRGGGRGNKHQGGW 383
           +GGRG   GG     SS  G GG + G  GG GG G     GY  GG  GGR     GG 
Sbjct: 521 SGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYG--SGGG 578

Query: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGG 441
           + GGS  GGGY  GG + S    GG  GG SSGG  G G GG   SSS  GS  +  G
Sbjct: 579 SKGGSISGGGYGSGGGKHS--SGGGSRGGSSSGGGYGSGGGG---SSSVKGSSGEAFG 631



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 53/132 (40%), Positives = 57/132 (43%), Gaps = 23/132 (17%)

Query: 338 GGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDG 397
           GG GG   SS GG        G GGR     GG GGG      G  + GG G GGG   G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGG------GSISGGGYGSGGG--SG 570

Query: 398 GYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDR 457
           G   SG   GG  GG  SGG  G G GG + SS   G G +GG          GG +G  
Sbjct: 571 GRYGSG---GGSKGGSISGG--GYGSGGGKHSS---GGGSRGGS-------SSGGGYGSG 615

Query: 458 GGGRGGRGGRGG 469
           GGG     G  G
Sbjct: 616 GGGSSSVKGSSG 627



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 45/115 (39%), Positives = 51/115 (44%), Gaps = 22/115 (19%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQ--------GGGRGGRGGYDHGGRGGGRGNKHQGGWTD 385
           GG G G GG+   S  G GG +         GGG G  GG+  GGRGGG G         
Sbjct: 49  GGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGF--GGRGGGFG--------- 97

Query: 386 GGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGG 440
           GGS  GGG    G+   GF  GG+ GG   G    GG GG      +   GY GG
Sbjct: 98  GGSSFGGG---SGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 41/107 (38%), Positives = 46/107 (42%), Gaps = 14/107 (13%)

Query: 325 RQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
           RQ G +  +GG GG   G  + S GG GG    GG    G    GG G G G    GG +
Sbjct: 544 RQSGSRGGSGG-GGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602

Query: 385 DGGSGGGGGYQDGGYRDSGFQPGGYHGGHSS-GGYQGGGYGGFQTSS 430
            GGS  GGGY  GG            GG SS  G  G  +G   T S
Sbjct: 603 RGGSSSGGGYGSGG------------GGSSSVKGSSGEAFGSSVTFS 637



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/77 (51%), Positives = 43/77 (55%), Gaps = 15/77 (19%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGG 393
           GGRGGG GG   SS+GG  G   GGG GG GG+  GGR GG G    G    GG GG GG
Sbjct: 90  GGRGGGFGG--GSSFGGGSGFS-GGGFGG-GGFG-GGRFGGFG----GPGGVGGLGGPGG 140

Query: 394 YQDGGYRDSGFQPGGYH 410
           +  GGY      PGG H
Sbjct: 141 FGPGGY------PGGIH 151



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 37/109 (33%), Positives = 42/109 (38%), Gaps = 19/109 (17%)

Query: 402 SGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGR 461
           + F   G  G  S GGY  G             S Y  GG Q  +R   GG     GGG 
Sbjct: 516 AAFGGSGGRGSSSGGGYSSGS------------SSYGSGGRQSGSRGGSGGGGSISGGGY 563

Query: 462 GGRGGRGGRGGRAG-------QGGGWGGRGSQNYHQGGQFEQHFQHGGY 503
           G  GG GGR G  G        GGG+G  G ++   GG        GGY
Sbjct: 564 GSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGY 612



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/128 (34%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 387 GSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDN 446
           G GGGGG   G    S    GG     SS        GG        G G+ GGG+   +
Sbjct: 11  GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGG--------GGGFGGGGFGSRS 62

Query: 447 RYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYN 506
               GG         GG GG G  GG  G+GGG+GG  S     G      F  GG  + 
Sbjct: 63  LVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSG------FSGGG--FG 114

Query: 507 HSGFGQGR 514
             GFG GR
Sbjct: 115 GGGFGGGR 122



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGR----GGRGGRGGRGGRAGQ 476
           GG GG  +SS   G GY  G     +  +  G  G  GGG     GG G  GG GGR G 
Sbjct: 519 GGSGGRGSSS---GGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGS 575

Query: 477 GGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHS---GFGQG 513
           GGG  G        G    +H   GG +   S   G+G G
Sbjct: 576 GGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG 615



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 15/99 (15%)

Query: 415 SGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474
           SGG      GG+ + SS  GSG +          Q G   G  GGG    GG G  GG  
Sbjct: 521 SGGRGSSSGGGYSSGSSSYGSGGR----------QSGSRGGSGGGGSISGGGYGSGGGSG 570

Query: 475 GQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQG 513
           G+ G  GG    +   GG     +  GG +++  G  +G
Sbjct: 571 GRYGSGGGSKGGSISGGG-----YGSGGGKHSSGGGSRG 604


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 56/198 (28%), Positives = 78/198 (39%), Gaps = 18/198 (9%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGN-----KHQGG 382
           G    + G+  G G +E SS       + G G G   G+   G G G+ +     + + G
Sbjct: 707 GQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSG 766

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYT--------G 434
            +  G    G  Q  GY   G +     G H SG  Q  G+G + + S  +        G
Sbjct: 767 QSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826

Query: 435 SGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQF 494
           SG   G  Q ++R     + G  G G     G G  G  +GQ  G+G    Q+    GQ+
Sbjct: 827 SGQSSGFGQHESRSHQSSY-GQHGSGSSQSSGYGQHGSSSGQTSGFG----QHRSSSGQY 881

Query: 495 EQHFQHGGYQYNHSGFGQ 512
               QHG      SGFGQ
Sbjct: 882 SGFGQHGSGSGQSSGFGQ 899



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 30/208 (14%)

Query: 331 QQTGGRGGGRGGYEHSSYGGR----GGHEQGGGRGGRGGYDHGGRG----GGRGNKHQGG 382
           Q   G G   G  +H S  G+    G HE   G+   G +  G       G  G++   G
Sbjct: 734 QHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSG 793

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
           +   GSG       G Y     Q  G+ G H SG  Q  G+G  ++ S  +  G  G G 
Sbjct: 794 FGQHGSGSSQSTGFGQYGSGSGQSAGF-GQHGSGSGQSSGFGQHESRSHQSSYGQHGSGS 852

Query: 443 QQDNRYQDGGHHGDRGGGRGGRG----------GRGGRGGRAGQGGGWG--GRGSQNYHQ 490
            Q + Y   G HG   G   G G          G G  G  +GQ  G+G  G GS  Y  
Sbjct: 853 SQSSGY---GQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSG 909

Query: 491 GGQFE------QHFQHGGYQYNHSGFGQ 512
            GQ E       + QHG      SG+GQ
Sbjct: 910 FGQHESRSHQSSYGQHGSGSSQSSGYGQ 937



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 68/214 (31%), Positives = 80/214 (37%), Gaps = 34/214 (15%)

Query: 328 GPQQQTGGRGGGRGGYE----HSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           G      G+  G G +E    HSSYG  G G  Q  G G  G       G G+     G 
Sbjct: 669 GQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQ 728

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPG-----GYH---------GGHSSGGYQGGGYGGFQT 428
            +  G  G G  Q  G+   G   G     G H         G HSSG  Q  GYG    
Sbjct: 729 SSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ-HG 787

Query: 429 SSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQ-- 486
           S   +G G  G G  Q   +      G  G G G   G G  G  +GQ  G+G   S+  
Sbjct: 788 SRQTSGFGQHGSGSSQSTGF------GQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSH 841

Query: 487 --NYHQGG----QFEQHFQHGGYQYNHSGFGQGR 514
             +Y Q G    Q   + QHG      SGFGQ R
Sbjct: 842 QSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHR 875



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 54/199 (27%), Positives = 76/199 (38%), Gaps = 23/199 (11%)

Query: 328  GPQQQTGGRGGGRGGYE----HSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
            G  +   G+  G G +E     S+YG  G G  Q  G G  G       G G+     G 
Sbjct: 975  GQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQ 1034

Query: 383  WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
            ++  G  G G  Q  G+           G H +G  Q  G+G +++ S  +  G  G G 
Sbjct: 1035 YSGFGQHGSGSDQSSGF-----------GQHGTGSGQSSGFGQYESRSRQSSYGQHGSGS 1083

Query: 443  QQDNRY-QDGGHHGDRGG------GRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFE 495
             Q + Y Q G + G   G      G G   G G  G  +GQ  G+G  GS      G  +
Sbjct: 1084 SQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQ 1143

Query: 496  QHFQHGGYQYNHSGFGQGR 514
              ++ G   Y   G G  +
Sbjct: 1144 HEYRSGQSSYGQHGTGSSQ 1162



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 62/198 (31%), Positives = 77/198 (38%), Gaps = 25/198 (12%)

Query: 328 GPQQQTGGRGGGRGGYE----HSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           G      G+  G G +E     SSYG  G G  Q  G G  G  +  G G       Q G
Sbjct: 519 GQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFG-------QHG 571

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
              G S G G Y  G  + SGF      G H SG  Q  G+G  ++ S  +  G    G 
Sbjct: 572 LGSGQSTGFGQYGSGSGQSSGF------GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGS 625

Query: 443 QQDNRYQDGGHHGDRGGGRGGRG-----GRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQH 497
            Q + Y   G     G G+ G G     G G  G  +GQ  G+G   S +    G F QH
Sbjct: 626 SQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSG-FGQH 684

Query: 498 FQHGGY-QYNHSGFGQGR 514
               G+  Y   GFG  +
Sbjct: 685 ESRSGHSSYGQHGFGSSQ 702



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 63/199 (31%), Positives = 79/199 (39%), Gaps = 19/199 (9%)

Query: 326 QDGPQQQTGGRGGGRGGYEHSSYGGRG---GHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
           Q G +Q +G    G G  + + +G  G   G   G G+ G G     G G      HQ  
Sbjct: 785 QHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSS 844

Query: 383 WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGH--SSGGYQGGGYGGFQTSSSY------TG 434
           +   GSG       G +  S  Q  G+ G H  SSG Y G G  G  +  S       TG
Sbjct: 845 YGQHGSGSSQSSGYGQHGSSSGQTSGF-GQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTG 903

Query: 435 SG-YQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
           SG Y G G  +   +Q    +G  G G     G G  G  +GQ  G+G    Q+    GQ
Sbjct: 904 SGQYSGFGQHESRSHQSS--YGQHGSGSSQSSGYGQHGSSSGQTFGFG----QHRSGSGQ 957

Query: 494 FEQHFQHGGYQYNHSGFGQ 512
                QHG      SGFGQ
Sbjct: 958 SSGFGQHGSGSGQSSGFGQ 976



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 57/202 (28%), Positives = 81/202 (40%), Gaps = 27/202 (13%)

Query: 326 QDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGN-----KHQ 380
           Q G ++ +G    G G  + + +G     + G G G   G+   G G G+ +     + +
Sbjct: 558 QYGSRETSGFGQHGLGSGQSTGFG-----QYGSGSGQSSGFGQHGSGSGQSSGFGQHESR 612

Query: 381 GGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSS--------Y 432
            G +  G    G  Q  GY   G +     G H SG  Q  G+G + + S          
Sbjct: 613 SGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHV 672

Query: 433 TGSGYQGGGYQQDNRYQDGGH--HGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQ 490
           +GSG   G  Q ++R    GH  +G  G G     G G  G  +GQ  G+G    Q+   
Sbjct: 673 SGSGQSSGFGQHESR---SGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFG----QHELS 725

Query: 491 GGQFEQHFQHGGYQYNHSGFGQ 512
            GQ     QHG      SGFGQ
Sbjct: 726 SGQSSSFGQHGSGSGQSSGFGQ 747



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 68/223 (30%), Positives = 86/223 (38%), Gaps = 49/223 (21%)

Query: 331 QQTGGRGGGRGGYEHSSYGGR----GGHEQGGGRGGRGGYDHGGRG----GGRGNKHQGG 382
           Q   G G   G  +H S  G+    G HE   G+   G +  G       G  G++   G
Sbjct: 582 QYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSG 641

Query: 383 WTDGGSG-----GGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGY 437
           +   GSG     G G Y  G  + SGF      G H SG  Q  G+G  ++ S ++  G 
Sbjct: 642 FGQHGSGSSQSTGFGQYGSGSGQSSGF------GQHVSGSGQSSGFGQHESRSGHSSYGQ 695

Query: 438 QGGGYQQDNRY-QDG---------GHH----------GDRGGGRGGRGGRGGRGGRAGQG 477
            G G  Q + Y Q G         G H          G  G G G   G G  G  +GQ 
Sbjct: 696 HGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQS 755

Query: 478 GGWG------GRGSQNYHQGG--QFEQHFQHGGYQYNHSGFGQ 512
            G+G      G+ S   H  G  Q   + QHG  Q   SGFGQ
Sbjct: 756 SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ--TSGFGQ 796



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 66/237 (27%), Positives = 86/237 (36%), Gaps = 56/237 (23%)

Query: 328  GPQQQTGGRGGGRGGYEHSS--YGGRGGHEQGGGRG------GRGGYDHGGRGGGRGNKH 379
            G    + G+  G G +  SS  Y G G H  G G+       G G   + G G      H
Sbjct: 859  GQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSH 918

Query: 380  QGGWTDGGSG------------------GGGGYQDGGYRDSGF--------QPGGYHGGH 413
            Q  +   GSG                  G G ++ G  + SGF        Q  G+ G H
Sbjct: 919  QSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGF-GQH 977

Query: 414  SSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG-------- 465
             SG  +  G+G  ++ SS +  G  G G  Q + Y   G HG   G   G G        
Sbjct: 978  ESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGY---GQHGSSSGQTTGFGQHRSSSGQ 1034

Query: 466  ----GRGGRGGRAGQGGGWGGRGSQNYHQGGQFE------QHFQHGGYQYNHSGFGQ 512
                G+ G G     G G  G GS      GQ+E       + QHG      SG+GQ
Sbjct: 1035 YSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQ 1091



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 62/203 (30%), Positives = 78/203 (38%), Gaps = 30/203 (14%)

Query: 331  QQTGGRGGGRGGYEHSSYGGR----GGHEQGGGRGGRGGYDHGGRGG-------GRGNKH 379
            Q   G G   G  +H S  G+    G HE G G+    G  H  R         G G+  
Sbjct: 950  QHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFG-QHESRSSQSNYGQHGSGSSQ 1008

Query: 380  QGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG 439
              G+   GS  G     G +R S  Q  G+ G H SG  Q  G+G   T S  + SG+  
Sbjct: 1009 SSGYGQHGSSSGQTTGFGQHRSSSGQYSGF-GQHGSGSDQSSGFGQHGTGSGQS-SGF-- 1064

Query: 440  GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGR----------AGQGGGWGGRGSQNYH 489
            G Y+  +R    G HG       G G  G   G+          +GQ  G+G  GS +  
Sbjct: 1065 GQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGS-- 1122

Query: 490  QGGQFEQHFQHGGYQYNHSGFGQ 512
              GQ     QHG      SGF Q
Sbjct: 1123 --GQSSGFGQHGSGTGKSSGFAQ 1143



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 55/199 (27%), Positives = 74/199 (37%), Gaps = 12/199 (6%)

Query: 325 RQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
           +  G +Q   G G   G +E +S    G  + G   G   G+   G G G+ +    G+ 
Sbjct: 438 QSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSS----GFG 493

Query: 385 DGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQ 444
             GSG G     G +     Q  G+ G H S   Q  G+G  ++ S  +  G  G G  Q
Sbjct: 494 QCGSGSGQSSGFGQHGSVSGQSSGF-GQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQ 552

Query: 445 DNRYQDGGHHGDRGGGRGGRG-------GRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQH 497
            + Y   G     G G+ G G       G+ G G     G G  G GS      GQ E  
Sbjct: 553 SSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESR 612

Query: 498 FQHGGYQYNHSGFGQGRHY 516
                Y  + SG  Q   Y
Sbjct: 613 SGQSSYGQHSSGSSQSSGY 631



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 58/201 (28%), Positives = 73/201 (36%), Gaps = 35/201 (17%)

Query: 332  QTGGRGGGRGGYEHSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGG 390
            Q+ G G        SSYG  G G  Q  G G  G       G G+     G ++  G  G
Sbjct: 829  QSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHG 888

Query: 391  GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
             G  Q  G+           G H +G  Q  G+G  ++ S  +  G  G G  Q + Y  
Sbjct: 889  SGSGQSSGF-----------GQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGY-- 935

Query: 451  GGHHGDRGG----------GRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQH--- 497
             G HG   G          G G   G G  G  +GQ  G+G   S +    G F QH   
Sbjct: 936  -GQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSG-FGQHESR 993

Query: 498  ------FQHGGYQYNHSGFGQ 512
                   QHG      SG+GQ
Sbjct: 994  SSQSNYGQHGSGSSQSSGYGQ 1014



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 61/216 (28%), Positives = 79/216 (36%), Gaps = 43/216 (19%)

Query: 328 GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH-QGGWTDG 386
           G  + T  +  G   +  SS    G  + G G G   G+   G G G+ +   Q G   G
Sbjct: 454 GQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSG 513

Query: 387 GSGGGGGYQDGGYRDSGFQPGGYH---------GGHSSGGYQGGGYGGFQT--------- 428
            S G G +     + SGF   G H         G H SG  Q  GYG + +         
Sbjct: 514 QSSGFGQHGSVSGQSSGF---GQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQH 570

Query: 429 ---SSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQG-------- 477
              S   TG G  G G  Q + +   G HG   G   G G    R G++  G        
Sbjct: 571 GLGSGQSTGFGQYGSGSGQSSGF---GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 627

Query: 478 -GGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQ 512
             G+G  GS+   Q   F    QHG      +GFGQ
Sbjct: 628 SSGYGQHGSR---QTSGFG---QHGSGSSQSTGFGQ 657



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 63/229 (27%), Positives = 80/229 (34%), Gaps = 43/229 (18%)

Query: 326 QDGPQQQTGGRGGGRGGYEHSSYGGRG-GHEQGGGRG----GRGGYDHGGRGGGRGNKHQ 380
           Q G +Q +G    G G  + + +G  G G  Q  G G    G G     G+   R     
Sbjct: 633 QHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSS 692

Query: 381 GGWTDGGSGGGGGY--------QDGGYRDSGFQPG-----GYHGG----------HSSGG 417
            G    GS    GY        Q  G+       G     G HG           H SG 
Sbjct: 693 YGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGS 752

Query: 418 YQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG-----GRGGRGG 472
            Q  G+G  ++ S  +  G    G  Q + Y   G     G G+ G G     G G  G 
Sbjct: 753 GQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGS 812

Query: 473 RAGQGGGWGGRGSQNYHQGGQFEQH---------FQHGGYQYNHSGFGQ 512
            +GQ  G+G  GS +    G F QH          QHG      SG+GQ
Sbjct: 813 GSGQSAGFGQHGSGSGQSSG-FGQHESRSHQSSYGQHGSGSSQSSGYGQ 860



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 67/210 (31%), Positives = 79/210 (37%), Gaps = 31/210 (14%)

Query: 330  QQQTG-GRGGGRGGYE----HSSYGGRG-GHEQGGGRGGRGGYDHGGRGGGR---GNKHQ 380
            Q  TG G+  G G YE     SSYG  G G  Q  G G  G       G G+   G+   
Sbjct: 1053 QHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQS 1112

Query: 381  GGWTDGGSGGG-----GGYQDGGYRDSGFQPGGY------HGGHSSGGYQGGGYGGFQTS 429
             G+   GSG G     G +  G  + SGF    Y      +G H +G  Q  G G  ++ 
Sbjct: 1113 SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESG 1172

Query: 430  SSYTGS-GYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNY 488
            S  T S G    G   DN    G H  D G       G G  G  +GQ  G G   SQ  
Sbjct: 1173 SGPTTSFGQHVSG--SDNFSSSGQHISDSGQST----GFGQYGSGSGQSTGLGQGESQQV 1226

Query: 489  HQGGQF--EQHFQHGG--YQYNHSGFGQGR 514
              G      Q   HG       HS  GQG+
Sbjct: 1227 ESGSTVHGRQETTHGQTINTTRHSQSGQGQ 1256



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 61/212 (28%), Positives = 82/212 (38%), Gaps = 35/212 (16%)

Query: 325 RQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRG-GRGGYDHGGRGGGRGNKHQGGW 383
           R++G  Q  GG+   R G   SS  G+ G   GG +    G +++G  G    +     +
Sbjct: 358 RENGQPQNCGGQW--RTGSSQSSCCGQYG--SGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413

Query: 384 TDGGSGGGGGYQDGGY--------RDSGFQP-----GGYHGGHSSGGYQGGGYGGFQTSS 430
           +     G G  Q   +        + SGF+      G   G H S   Q  GY    +SS
Sbjct: 414 SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSS 473

Query: 431 SYT-GSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYH 489
             T G G  G G  Q + +      G  G G G   G G  G  +GQ  G+G  GS +  
Sbjct: 474 GKTSGFGQHGSGSGQSSGF------GQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQ 527

Query: 490 QGGQFEQH---------FQHGGYQYNHSGFGQ 512
             G F QH          QHG      SG+GQ
Sbjct: 528 SSG-FGQHESRSRQSSYGQHGSGSSQSSGYGQ 558



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 56/215 (26%), Positives = 76/215 (35%), Gaps = 37/215 (17%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHE-----QGGGRGGRGGYDHGGRGGGRGNKHQGG 382
            G   Q G R  GR    HS Y    GH        G   G+ G  HG  G     +H  G
Sbjct: 2013 GQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERH--G 2070

Query: 383  WTDGGSG--------GGG-----GYQDGGYRDSGFQPGGYHGGHS--SGGYQGGGYGGFQ 427
             T G +G        G G     G +  G R SG         HS  S  + G  YG  +
Sbjct: 2071 TTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQAR 2130

Query: 428  TSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQN 487
            +    +GS   G         + G  HG  G     R G+ G G     G    GR   +
Sbjct: 2131 SQHGESGSAIHG---------RQGTIHGQTGDTT--RHGQSGHGQSTQTGSRTTGRQRSS 2179

Query: 488  YHQGGQFEQHFQ----HGGYQYNHSGFGQGRHYTS 518
            + +    E H +    H G+ ++ +G   G+  +S
Sbjct: 2180 HSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSS 2214



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 59/230 (25%), Positives = 77/230 (33%), Gaps = 46/230 (20%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK-----HQGG 382
            G   QTG R  GR    HS Y    GH     R    G+ HG  G   G        + G
Sbjct: 1786 GQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHG 1845

Query: 383  WTDGGSGGGGGYQDGGYRDS----GFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQ 438
             T G +G   G+   G+  S        G    GHS         GG  T S +T S  +
Sbjct: 1846 TTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQAR 1905

Query: 439  GGGYQQDN----RYQ----------DGGH--------HGDRGGGRGGRG------GRGGR 470
                + ++    R+Q          + GH         G R  GR G G        G  
Sbjct: 1906 SQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPS 1965

Query: 471  GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHG--------GYQYNHSGFGQ 512
            G      G   G+   +Y + G    H +HG          ++ HSG GQ
Sbjct: 1966 GVSHTHSGHTHGQAGSHYPESGS-SVHERHGTTHGQTADTTRHGHSGHGQ 2014



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 59/227 (25%), Positives = 71/227 (31%), Gaps = 42/227 (18%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRG-----GHEQGGGRGGRGGYDHGGRG----GGRGNK 378
            G   Q G R  GR G  HS            H   G   G+    HG  G    G +G  
Sbjct: 2088 GQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTI 2147

Query: 379  H--QGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGG-----HSSGGYQGGGYGGFQTSSS 431
            H   G  T  G  G G     G R +G Q   +        HS       G+   Q  S 
Sbjct: 2148 HGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSR 2207

Query: 432  YTGSGYQGGGYQQDNRYQDG-----GHHG-----DRGGGRGGRGGRGGRGGRAGQGGGWG 481
            +  SG  G G Q     Q G      H+G      RG    GR G G       +   WG
Sbjct: 2208 HGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWG 2267

Query: 482  GRGSQNYHQGGQFEQHFQHGG----------------YQYNHSGFGQ 512
                  + QG    Q  Q G                  ++ HSG+GQ
Sbjct: 2268 SHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQ 2314



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 48/193 (24%), Positives = 63/193 (32%), Gaps = 16/193 (8%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGG-----HEQGGGRGGRGGYDHGGRGGGRGNKH--- 379
            G   QTG R  GR G  HS Y    G     H   G   G+    HG        +H   
Sbjct: 1711 GLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTI 1770

Query: 380  ---QGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSG 436
                G  T     G G     G R +G +  G+     S G+ G          ++  +G
Sbjct: 1771 HGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAG 1830

Query: 437  YQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQ 496
             Q G  +     + G  HG  G   G    + G G     G    GR    + +    E 
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSG--HSQSGHGQSTQSGSSTTGRRRSGHSESSDSE- 1887

Query: 497  HFQHGGYQYNHSG 509
               H G  + HSG
Sbjct: 1888 --VHSGGSHTHSG 1898



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 57/208 (27%), Positives = 73/208 (35%), Gaps = 38/208 (18%)

Query: 330  QQQTGGRGGGRGGYEHSSYGGRGGHEQGG-GRGGRGGYDHGGRGGGRGNKHQGGWTDGGS 388
            Q+QT G+ G + G   S+  GR G   G  G   R  + H G+   RG+      T G  
Sbjct: 1443 QEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSS-----TTGRR 1497

Query: 389  GGGGGYQDGGYRDSGFQPGG--YHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDN 446
            G G         DS    GG   H GH+ G  Q G   G   S  +       G      
Sbjct: 1498 GSGHSESS----DSEVHSGGSHTHSGHTHG--QSGSQHGESESIIHDRHRITHGQTGDTT 1551

Query: 447  RYQDGGHH-----GDRGGGRGGRGGRGGRGGRAGQGGG---------WGGRGSQNYHQGG 492
            R+   GH      G R  GR               GG          +G  GSQ  H+  
Sbjct: 1552 RHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQ--HEEP 1609

Query: 493  QFEQHFQHGGYQ--------YNHSGFGQ 512
            +F  H +HG           ++HSG GQ
Sbjct: 1610 EFTVHERHGTTHGQIGDTTGHSHSGHGQ 1637



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 43/188 (22%), Positives = 62/188 (32%), Gaps = 11/188 (5%)

Query: 333  TGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQ------GGWTDG 386
            TG RG G      S     G H   G   G+ G  HG       ++H+      G  T  
Sbjct: 1494 TGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRH 1553

Query: 387  GSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDN 446
               G       G R +G Q   +     S  + GG +       +Y  +G Q    +   
Sbjct: 1554 SYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTV 1613

Query: 447  RYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYN 506
              + G  HG  G   G      G G    +G    GR   ++ +    E    H G  + 
Sbjct: 1614 HERHGTTHGQIGDTTG--HSHSGHGQSTQRGSRTTGRQRSSHSESSDSE---VHSGVSHT 1668

Query: 507  HSGFGQGR 514
            H+G   G+
Sbjct: 1669 HTGHTHGQ 1676



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 46/205 (22%), Positives = 64/205 (31%), Gaps = 23/205 (11%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGR-------GGRGGYDHGGRGGGRGNKHQ 380
            G   QTG R  GR  + HS       H     R         + G  HG        +H+
Sbjct: 1330 GQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHE 1389

Query: 381  ------GGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTG 434
                  G  T  G  G G     G R +G +  G+     S  + GG +       ++  
Sbjct: 1390 TTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQ 1449

Query: 435  SGYQGGGYQQDNRYQDGGHHGDRGGG------RGGRGGRGGRGGRAGQGGGWGGRGSQNY 488
            +G Q G        + G  HG  G          G+  + G      +G G         
Sbjct: 1450 AGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEV 1509

Query: 489  HQGGQFEQHFQHGGYQYNHSGFGQG 513
            H GG       H G+ +  SG   G
Sbjct: 1510 HSGGS----HTHSGHTHGQSGSQHG 1530



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/252 (26%), Positives = 82/252 (32%), Gaps = 79/252 (31%)

Query: 335 GRGGGRGGYEHSSYGGRGGHEQG-------GGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
           GR     GY +SS  GR  +          GG+G +  Y   G   G       G   GG
Sbjct: 274 GRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGG 333

Query: 388 SGGGGG----------YQDGGY--RDSGFQP-----------------GGYHGGH----S 414
              G G          Y   GY  R++G QP                 G Y  G     S
Sbjct: 334 QPSGCGQPESNPCSQSYSQRGYGARENG-QPQNCGGQWRTGSSQSSCCGQYGSGGSQSCS 392

Query: 415 SGGYQGGGYGGFQTSSSYT--------GSG--------YQGGGYQQDNRYQD-------- 450
           +G ++ G  G F  SSS          GSG          G G  Q + ++         
Sbjct: 393 NGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQT 452

Query: 451 -GGH---------HGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500
            G H         +   G   G   G G  G  +GQ  G+G  GS +    GQ     QH
Sbjct: 453 CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGS----GQSSGFGQH 508

Query: 501 GGYQYNHSGFGQ 512
           G      SGFGQ
Sbjct: 509 GSVSGQSSGFGQ 520



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/203 (23%), Positives = 68/203 (33%), Gaps = 19/203 (9%)

Query: 328  GPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
            G  +   G+  G G Y   S    G  + G G G   G+       G+ +  Q G     
Sbjct: 1103 GQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQ 1162

Query: 388  SGGGGGYQDG-------GYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGG 440
            S G G ++ G       G   SG       G H S   Q  G+G +      +GSG   G
Sbjct: 1163 SSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYG-----SGSGQSTG 1217

Query: 441  GYQQDNRYQDGGH--HGDRGGGRG-----GRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
              Q +++  + G   HG +    G      R  + G+G     G     R   +  +   
Sbjct: 1218 LGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSD 1277

Query: 494  FEQHFQHGGYQYNHSGFGQGRHY 516
             E H +       H     G HY
Sbjct: 1278 SEVHSKVSHRHSEHIHTQAGSHY 1300



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 54/225 (24%), Positives = 76/225 (33%), Gaps = 39/225 (17%)

Query: 323 QKRQDGPQQQTGGRGGGRGGYEHSSY--GGRGGHEQGGGRG-------------GRGG-- 365
           Q+ +   ++      G + GY HSS+  G   G+  G  RG             GR G  
Sbjct: 109 QEEESETEEDEEDTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNL 168

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGY--------------RDSGFQPGGYHG 411
              G + G +   H+       SGG   +                   R+SG +   Y  
Sbjct: 169 SSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEE---YES 225

Query: 412 GHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG 471
           G  S  ++  G+GG   S     SG++    Q   R Q  G      G  G R    G  
Sbjct: 226 GSGSNSWERKGHGGL--SCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYS 283

Query: 472 GRAGQGGGWGGRGS-QNYHQGGQFEQ--HFQHGGYQYNHSGFGQG 513
             +G G       S Q++  GGQ  Q  + Q G       G G G
Sbjct: 284 NSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHG 328



 Score = 37.0 bits (84), Expect = 0.043
 Identities = 39/169 (23%), Positives = 55/169 (32%), Gaps = 10/169 (5%)

Query: 346  SSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQ 405
            +++G RG   + G  G       G R  GR        TD     G  ++      +  Q
Sbjct: 1313 TTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQ 1372

Query: 406  PGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG 465
             G  HG   S  ++       QT  + TG G+ G G             G R  GR G G
Sbjct: 1373 AGSQHGESESTVHERHETTYGQTGEA-TGHGHSGHG--------QSTQRGSRTTGRRGSG 1423

Query: 466  GRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
                       GG    +  +  H G    QH + G   +   G   G+
Sbjct: 1424 HSESSDSEVHSGGSHRPQSQEQTH-GQAGSQHGESGSTVHGRHGTTHGQ 1471



 Score = 35.8 bits (81), Expect = 0.097
 Identities = 45/208 (21%), Positives = 69/208 (33%), Gaps = 17/208 (8%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGG 382
            ++R+    + +      +  + HS +     H Q G    + G     R  G  +  +G 
Sbjct: 1266 RRRRSSQSENSDSEVHSKVSHRHSEHI----HTQAGSHYPKSG-STVRRRQGTTHGQRGD 1320

Query: 383  WTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
             T  G  G G     G R SG Q   +     S  + G  +       +++ +G Q G  
Sbjct: 1321 TTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGES 1380

Query: 443  QQDNRYQDGGHHGDRGG----GRGGRGGRGGRGGRAG--QGGGWGGRGSQNYHQGG---- 492
            +     +    +G  G     G  G G    RG R    +G G         H GG    
Sbjct: 1381 ESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRP 1440

Query: 493  --QFEQHFQHGGYQYNHSGFGQGRHYTS 518
              Q + H Q G           GRH T+
Sbjct: 1441 QSQEQTHGQAGSQHGESGSTVHGRHGTT 1468



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 12/129 (9%)

Query: 323  QKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGG---GRGNKH 379
            Q  Q G  + TG RG G      S     G H   G   G+ G      G    GR    
Sbjct: 2239 QSTQRG-SRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETT 2297

Query: 380  QGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGG--------YQGGGYGGFQTSSS 431
             G   D    G  GY       S      +   HSS          ++ G YG  +    
Sbjct: 2298 HGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYG 2357

Query: 432  YTGSGYQGG 440
            +TG G  GG
Sbjct: 2358 HTGYGPSGG 2366


>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 58/137 (42%), Positives = 66/137 (48%), Gaps = 22/137 (16%)

Query: 321 PWQKRQDGPQQQTGGRGGGR-GGYEHSSYGGRGGHEQGG---GRGGRGGYDHGGRGGGRG 376
           P Q+       Q G RG G  GG     +GG     +GG   GRGG GG   GG  GG G
Sbjct: 182 PKQEMASASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSG 241

Query: 377 NKHQGGWTDGGS-GGGGGYQD-GGY--RDSGFQP--GGYHGGHSSGGYQG---------- 420
           + + G   DG + GGGG Y D G Y  + S F P  GG  GG SSG Y G          
Sbjct: 242 DGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQN 301

Query: 421 -GGYGGFQTSSSYTGSG 436
            GGYG   +SSSY GSG
Sbjct: 302 QGGYGVSSSSSSY-GSG 317



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 60/175 (34%), Positives = 74/175 (42%), Gaps = 50/175 (28%)

Query: 346 SSYGGRGGHEQGGGRG-GRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGF 404
           S  G RG    GGGRG G GG D+ GRGG    +  GG+  GGS GGGGY          
Sbjct: 192 SQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGR--GGF--GGSCGGGGY---------- 237

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGR 464
                       G  G GY GF       GS + GGG      Y D G++ ++    G  
Sbjct: 238 ------------GGSGDGYNGFGND----GSNFGGGG-----SYNDFGNYNNQSSNFGPM 276

Query: 465 GGRGGRGGRAGQGGGWGGRGSQNYHQGGQ-FEQHFQHGGY--QYNHSGFGQGRHY 516
                      +GG +GGR S  Y  GGQ F +    GGY    + S +G GR +
Sbjct: 277 -----------KGGNFGGRSSGPYGGGGQYFAKPQNQGGYGVSSSSSSYGSGRRF 320


>gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 58/137 (42%), Positives = 66/137 (48%), Gaps = 22/137 (16%)

Query: 321 PWQKRQDGPQQQTGGRGGGR-GGYEHSSYGGRGGHEQGG---GRGGRGGYDHGGRGGGRG 376
           P Q+       Q G RG G  GG     +GG     +GG   GRGG GG   GG  GG G
Sbjct: 182 PKQEMASASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSG 241

Query: 377 NKHQGGWTDGGS-GGGGGYQD-GGY--RDSGFQP--GGYHGGHSSGGYQG---------- 420
           + + G   DG + GGGG Y D G Y  + S F P  GG  GG SSG Y G          
Sbjct: 242 DGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQN 301

Query: 421 -GGYGGFQTSSSYTGSG 436
            GGYG   +SSSY GSG
Sbjct: 302 QGGYGVSSSSSSY-GSG 317



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 60/175 (34%), Positives = 74/175 (42%), Gaps = 50/175 (28%)

Query: 346 SSYGGRGGHEQGGGRG-GRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGF 404
           S  G RG    GGGRG G GG D+ GRGG    +  GG+  GGS GGGGY          
Sbjct: 192 SQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGR--GGF--GGSCGGGGY---------- 237

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGR 464
                       G  G GY GF       GS + GGG      Y D G++ ++    G  
Sbjct: 238 ------------GGSGDGYNGFGND----GSNFGGGG-----SYNDFGNYNNQSSNFGPM 276

Query: 465 GGRGGRGGRAGQGGGWGGRGSQNYHQGGQ-FEQHFQHGGY--QYNHSGFGQGRHY 516
                      +GG +GGR S  Y  GGQ F +    GGY    + S +G GR +
Sbjct: 277 -----------KGGNFGGRSSGPYGGGGQYFAKPQNQGGYGVSSSSSSYGSGRRF 320


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 63/156 (40%), Positives = 70/156 (44%), Gaps = 39/156 (25%)

Query: 333 TGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGG 392
           +GG GGG       +YG R G    GG G R  Y+ GG      +   GG   GG GGG 
Sbjct: 35  SGGAGGG-------AYGFRSG---AGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGG- 83

Query: 393 GYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGG 452
                  R S    GGY GG  SG   GGG+GG          G+ GG      R   GG
Sbjct: 84  -------RSSCAFAGGYGGGFGSG--YGGGFGG----------GFGGG------RGMGGG 118

Query: 453 HHGDRG-GGRGGRGGRGGRGGRAGQG--GGWGGRGS 485
             G  G GG GG GG GG GG  G G  GG+GG GS
Sbjct: 119 FGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGS 154



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 62/169 (36%), Positives = 72/169 (42%), Gaps = 38/169 (22%)

Query: 330 QQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSG 389
           +Q +   GGG  G+      GR     G  R     +  GG GGG      G    GG G
Sbjct: 3   RQASKTSGGGSQGFS-----GRSAVVSGSSRMSCVAHS-GGAGGGAYGFRSGA---GGFG 53

Query: 390 GGGGYQDGGYRD-------SGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442
               Y  GG +         G + GG+ GG SS  + GG  GGF       GSGY GGG+
Sbjct: 54  SRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGF-------GSGY-GGGF 105

Query: 443 QQDNRYQDGGHHGDRG-----GGRGGRGGRGGRGGRAGQG--GGWGGRG 484
                   GG  G RG     GG GG GG GG GG  G G  GG+GG G
Sbjct: 106 -------GGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSG 147



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 39/83 (46%), Positives = 43/83 (51%), Gaps = 8/83 (9%)

Query: 334 GGRGGGRGGYEHSSYGGR--GGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG 391
           GG GGG G      +GG   GG   GGG GG GG+  GG GG  G    GG   GG GG 
Sbjct: 91  GGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGF--GGAGGFGGAGGFGG--PGGFGGS 146

Query: 392 GGYQDGGYRDS--GFQPGGYHGG 412
           GG+   G   S  GF PGG+ GG
Sbjct: 147 GGFGGPGSLGSPGGFGPGGFPGG 169



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 43/109 (39%), Positives = 50/109 (45%), Gaps = 15/109 (13%)

Query: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGG 393
           G R GG GG   SS    GG+  G G G  GG+  GG GGGRG         GG GG GG
Sbjct: 74  GSRAGGFGG-GRSSCAFAGGYGGGFGSGYGGGFG-GGFGGGRG-------MGGGFGGAGG 124

Query: 394 YQDGGYRDSGFQ-PGGYHGGHSSGGYQG-GGYGGFQTSSSYTGSGYQGG 440
           +   G    GF   GG+ G    GG  G GG G   +   +   G+ GG
Sbjct: 125 FGGAG----GFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGG 169



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 41/104 (39%), Positives = 45/104 (43%), Gaps = 11/104 (10%)

Query: 346 SSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDG-GYRDSGF 404
           +S GG GG   GG  GG GG    G G G G          G GGGGG   G G   SGF
Sbjct: 533 ASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGF---------GRGGGGGIGGGFGGGSSGF 583

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRY 448
             GG   G  SG   G   GGF ++S+  GS       Q   RY
Sbjct: 584 S-GGSGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRY 626



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 36/97 (37%), Positives = 43/97 (44%), Gaps = 21/97 (21%)

Query: 407 GGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGG 466
           GGY GG+  GG  GGG GG  ++   +GSG+  GG                GGG GG G 
Sbjct: 536 GGYGGGY--GGGMGGGLGGGFSAGGGSGSGFGRGG----------------GGGIGG-GF 576

Query: 467 RGGRGGRAGQGGGWGGRGSQNYH-QGGQFEQHFQHGG 502
            GG  G +G G G+G      Y   GG F      GG
Sbjct: 577 GGGSSGFSG-GSGFGSISGARYGVSGGGFSSASNRGG 612



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 14/87 (16%)

Query: 428 TSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGG-R--GGRGGRGGRGGRAGQGGGWGGRG 484
           +S++   +G  GGGY        GG  G  GGG    GG G   GRGG  G GGG+GG G
Sbjct: 528 SSTTSASAGGYGGGY-------GGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGG-G 579

Query: 485 SQNYHQGGQFEQHFQHGGYQYNHSGFG 511
           S  +  G  F       G +Y  SG G
Sbjct: 580 SSGFSGGSGFG---SISGARYGVSGGG 603



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 8/74 (10%)

Query: 334 GGRGGGRGGYEHSS-YGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGG 392
           GG  GG GG+  +  +GG GG    GG GG GG+   G  G  G    GG+        G
Sbjct: 116 GGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFP-------G 168

Query: 393 GYQDGGYRDSGFQP 406
           G Q+     S  QP
Sbjct: 169 GIQEVTINQSLLQP 182



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 2/46 (4%)

Query: 468 GGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQG 513
           GG GG  G GGG GG     +  GG     F  GG      GFG G
Sbjct: 536 GGYGG--GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGG 579


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
          Length = 1270

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 8/102 (7%)

Query: 391  GGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQD 450
            G GY+ GG   S +  GGY GG+SSGGY  GGYGG   S         GGGY+  +R   
Sbjct: 1170 GSGYRRGG---SSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR--- 1223

Query: 451  GGHHGDRGGG-RGGRGGRGGRGGRAGQGGGWGGRGSQNYHQG 491
            GG  G+ GG  RG  GG  G GG   +GGG G  G+  + QG
Sbjct: 1224 GGFRGNSGGDYRGPSGGYRGSGG-FQRGGGRGAYGTGYFGQG 1264



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 12/121 (9%)

Query: 327  DGPQQQTGGRGGGRGGYEH--SSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWT 384
            DGP+     R     GY    SSY G GG+   GG    GGY  GG GG   N  + G+ 
Sbjct: 1157 DGPRPPKMARYDNGSGYRRGGSSYSG-GGY---GGGYSSGGYGSGGYGGS-ANSFRAGYG 1211

Query: 385  DGGSGGGGGYQDGGYR-DSGFQPGGYHGGH-SSGGYQ-GGGYGGFQTSSSYTGSGYQGGG 441
             G  GG  G   GG+R +SG    G  GG+  SGG+Q GGG G + T   Y G G  GGG
Sbjct: 1212 AGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGT--GYFGQGRGGGG 1269

Query: 442  Y 442
            Y
Sbjct: 1270 Y 1270



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 49/120 (40%), Positives = 55/120 (45%), Gaps = 19/120 (15%)

Query: 314  PPPPEMPPWQK----RQDGPQQQTGGRGGG--RGGYEHSSYGGRGGHEQGG-GRGGRGGY 366
            P PP+M  +      R+ G     GG GGG   GGY    YGG     + G G G  GGY
Sbjct: 1159 PRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGY 1218

Query: 367  DHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSG-FQPGGYHGGHSSGGYQGGGYGG 425
                RGG RGN          SGG      GGYR SG FQ GG  G + +G Y G G GG
Sbjct: 1219 RGVSRGGFRGN----------SGGDYRGPSGGYRGSGGFQRGGGRGAYGTG-YFGQGRGG 1267



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 43/108 (39%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 366  YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425
            YD+G  G  RG     G   GG    GGY  GGY  S       +G    GGY+G   GG
Sbjct: 1167 YDNGS-GYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGG 1225

Query: 426  FQTSSSYTGSGYQG--GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRG 471
            F+ +S   G  Y+G  GGY+    +Q GG  G  G G  G+ GRGG G
Sbjct: 1226 FRGNS---GGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQ-GRGGGG 1269



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 41/107 (38%), Positives = 47/107 (43%), Gaps = 13/107 (12%)

Query: 408  GYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGR 467
            GY  G SS  Y GGGYGG  +S  Y   GY G      N ++ G   G  GG RG     
Sbjct: 1172 GYRRGGSS--YSGGGYGGGYSSGGYGSGGYGGSA----NSFRAGYGAGVGGGYRGV---- 1221

Query: 468  GGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
              RGG  G  GG     S  Y   G F++    G Y   +  FGQGR
Sbjct: 1222 -SRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGY--FGQGR 1265


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 67/213 (31%), Positives = 81/213 (38%), Gaps = 31/213 (14%)

Query: 298 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQG 357
           + G +P R GR   + PP    P       GP  + GGRGG RGG+      G  G+  G
Sbjct: 398 MRGGLPPREGRG--MPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 455

Query: 358 GGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGG 417
           GG       D      G GN++    T+         +  G+    F P G   G    G
Sbjct: 456 GGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP--KPEGFLPPPFPPPGGDRGRGGPG 513

Query: 418 YQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG------GRGGRG 471
              GG GG          G  GG ++       GG  GDRGG RGGRG      G G RG
Sbjct: 514 GMRGGRGGLMDR------GGPGGMFR-------GGRGGDRGGFRGGRGMDRGGFGGGRRG 560

Query: 472 GRAG--------QGGGWGGRGSQNYHQGGQFEQ 496
           G  G         GG  GGRG       G+  Q
Sbjct: 561 GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQ 593



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)

Query: 343 YEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGR---------GNKHQGGWTDGGSGGGGG 393
           Y+ SSY  +  + Q    G +  Y      G +         G+  Q            G
Sbjct: 147 YDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG 206

Query: 394 YQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGH 453
            Q    +D     G Y  G  SGG+ G G     +     G G   GG+ +      G  
Sbjct: 207 QQSSFRQDHPSSMGVY--GQESGGFSGPGENRSMSGPDNRGRGR--GGFDRG-----GMS 257

Query: 454 HGDRGGGRGGRGGRGGRGGRAGQGG 478
            G RGGGRGG G  G RGG    GG
Sbjct: 258 RGGRGGGRGGMGSAGERGGFNKPGG 282



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 325 RQDGPQQQTGGRGGGRGGY----EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQ 380
           RQD P    G  G   GG+    E+ S  G     +G G   RGG   GGRGGGRG    
Sbjct: 212 RQDHPSSM-GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270

Query: 381 GGWTDGGSGGGGGYQDGGYRDSG 403
            G   G +  GG   +G   D G
Sbjct: 271 AGERGGFNKPGGPMDEGPDLDLG 293



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 10/101 (9%)

Query: 405 QPGGYHGGHSSGGYQGGGYGGFQT-----SSSYTGSGYQGGGYQQDNRYQDGGHHGDRGG 459
           Q G Y    S    Q   YG   +      SS    G + GG+      +      +RG 
Sbjct: 187 QTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGR 246

Query: 460 GRGG--RGG--RGGRGGRAGQGGGWGGRGSQNYHQGGQFEQ 496
           GRGG  RGG  RGGRGG  G  G  G RG  N   GG  ++
Sbjct: 247 GRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN-KPGGPMDE 286



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 452 GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFG 511
           G  G  GG  G  G  GGRGG  G     G RGS+    GG   QH + G +Q  + G G
Sbjct: 416 GGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAGDWQCPNPGCG 474



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 22/111 (19%)

Query: 313 EPP---PPEMPPWQKRQDGPQQQTGGRGGGRG-GYEHSSYGGRGGHEQGGGRG-----GR 363
           +PP   PP+   + +      QQ+   G       +H S  G  G E GG  G       
Sbjct: 179 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 238

Query: 364 GGYDHGGRGGGRGNKHQGGWTDGG------SGGGGGYQDGGYRDSGFQPGG 408
            G D+ GRG       +GG+  GG       GG GG    G R    +PGG
Sbjct: 239 SGPDNRGRG-------RGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGG 282


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 67/213 (31%), Positives = 81/213 (38%), Gaps = 31/213 (14%)

Query: 298 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQG 357
           + G +P R GR   + PP    P       GP  + GGRGG RGG+      G  G+  G
Sbjct: 453 MRGGLPPREGRG--MPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 510

Query: 358 GGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGG 417
           GG       D      G GN++    T+         +  G+    F P G   G    G
Sbjct: 511 GGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP--KPEGFLPPPFPPPGGDRGRGGPG 568

Query: 418 YQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG------GRGGRG 471
              GG GG          G  GG ++       GG  GDRGG RGGRG      G G RG
Sbjct: 569 GMRGGRGGLMDR------GGPGGMFR-------GGRGGDRGGFRGGRGMDRGGFGGGRRG 615

Query: 472 GRAG--------QGGGWGGRGSQNYHQGGQFEQ 496
           G  G         GG  GGRG       G+  Q
Sbjct: 616 GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQ 648



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 313 EPP---PPEMPPWQKRQDGPQQQTGGRGGGRG-GYEHSSYGGRGGHEQGGGRGGRGGYDH 368
           +PP   PP+   + +      QQ+   G       +H S  G  G E GG  G       
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294

Query: 369 GG---RGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGG 408
            G   RG GRG   +GG + GG GGG G    G R    +PGG
Sbjct: 295 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG 337



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 7/78 (8%)

Query: 325 RQDGPQQQTGGRGGGRGGY----EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQ 380
           RQD P    G  G   GG+    E+ S  G     +G G   RGG   GGRGGGRG    
Sbjct: 268 RQDHPSSM-GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG--M 324

Query: 381 GGWTDGGSGGGGGYQDGG 398
           G    GG    GG  D G
Sbjct: 325 GAGERGGFNKPGGPMDEG 342



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 52/193 (26%), Positives = 66/193 (34%), Gaps = 30/193 (15%)

Query: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
           G  P +    PP  PP       P             Y+ SSY  +  + Q    G +  
Sbjct: 177 GSYPMQPVTAPPSYPPTSYSSTQPTS-----------YDQSSYSQQNTYGQPSSYGQQSS 225

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425
           Y   G+    G +    +           Q G Y  +   P  Y    SS G Q      
Sbjct: 226 Y---GQQSSYGQQPPTSYPP---------QTGSYSQA---PSQYSQQSSSYGQQSSFRQD 270

Query: 426 FQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGG--RGGRGGRAGQGGGWGGR 483
             +S    G    G     +NR   G  +  RG G   RGG  RGGRGG  G G G G R
Sbjct: 271 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-GMGAGER 329

Query: 484 GSQNYHQGGQFEQ 496
           G  N   GG  ++
Sbjct: 330 GGFN-KPGGPMDE 341



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 64/250 (25%), Positives = 87/250 (34%), Gaps = 66/250 (26%)

Query: 320 PPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH 379
           P   +   GP      RG GRGG++      RGG  +GGGRGG G  + GG     G   
Sbjct: 288 PGENRSMSGPDN----RGRGRGGFDRGGMS-RGG--RGGGRGGMGAGERGGFNKPGGPMD 340

Query: 380 QGGWTDGG--------SGGGGGYQDG------------GYRDSGFQPGGYHGGH------ 413
           +G   D G        S     Y  G             ++  G        G       
Sbjct: 341 EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 400

Query: 414 ---SSGGYQGGGYGGFQTSSS-------YTGSGYQGGGYQQDNRYQDGGHHGDRGG---- 459
               +G  +G     ++   +       + G  +QG   +     +    +  RGG    
Sbjct: 401 LDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR 460

Query: 460 -GRG-------GRGGRGGRGGRAGQGGGWGG----------RGSQNYHQGGQFEQHFQHG 501
            GRG       G GG GG GG  G+ GG GG          RGS+    GG   QH + G
Sbjct: 461 EGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAG 519

Query: 502 GYQYNHSGFG 511
            +Q  + G G
Sbjct: 520 DWQCPNPGCG 529


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 67/213 (31%), Positives = 81/213 (38%), Gaps = 31/213 (14%)

Query: 298 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQG 357
           + G +P R GR   + PP    P       GP  + GGRGG RGG+      G  G+  G
Sbjct: 459 MRGGLPPREGRG--MPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 516

Query: 358 GGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGG 417
           GG       D      G GN++    T+         +  G+    F P G   G    G
Sbjct: 517 GGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP--KPEGFLPPPFPPPGGDRGRGGPG 574

Query: 418 YQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG------GRGGRG 471
              GG GG          G  GG ++       GG  GDRGG RGGRG      G G RG
Sbjct: 575 GMRGGRGGLMDR------GGPGGMFR-------GGRGGDRGGFRGGRGMDRGGFGGGRRG 621

Query: 472 GRAG--------QGGGWGGRGSQNYHQGGQFEQ 496
           G  G         GG  GGRG       G+  Q
Sbjct: 622 GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQ 654



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 313 EPP---PPEMPPWQKRQDGPQQQTGGRGGGRG-GYEHSSYGGRGGHEQGGGRGGRGGYDH 368
           +PP   PP+   + +      QQ+   G       +H S  G  G E GG  G       
Sbjct: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300

Query: 369 GG---RGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGG 408
            G   RG GRG   +GG + GG GGG G    G R    +PGG
Sbjct: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG 343



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 7/78 (8%)

Query: 325 RQDGPQQQTGGRGGGRGGY----EHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQ 380
           RQD P    G  G   GG+    E+ S  G     +G G   RGG   GGRGGGRG    
Sbjct: 274 RQDHPSSM-GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG--M 330

Query: 381 GGWTDGGSGGGGGYQDGG 398
           G    GG    GG  D G
Sbjct: 331 GAGERGGFNKPGGPMDEG 348



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 52/193 (26%), Positives = 66/193 (34%), Gaps = 30/193 (15%)

Query: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
           G  P +    PP  PP       P             Y+ SSY  +  + Q    G +  
Sbjct: 183 GSYPMQPVTAPPSYPPTSYSSTQPTS-----------YDQSSYSQQNTYGQPSSYGQQSS 231

Query: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425
           Y   G+    G +    +           Q G Y  +   P  Y    SS G Q      
Sbjct: 232 Y---GQQSSYGQQPPTSYPP---------QTGSYSQA---PSQYSQQSSSYGQQSSFRQD 276

Query: 426 FQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGG--RGGRGGRAGQGGGWGGR 483
             +S    G    G     +NR   G  +  RG G   RGG  RGGRGG  G G G G R
Sbjct: 277 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-GMGAGER 335

Query: 484 GSQNYHQGGQFEQ 496
           G  N   GG  ++
Sbjct: 336 GGFN-KPGGPMDE 347



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 64/250 (25%), Positives = 87/250 (34%), Gaps = 66/250 (26%)

Query: 320 PPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKH 379
           P   +   GP      RG GRGG++      RGG  +GGGRGG G  + GG     G   
Sbjct: 294 PGENRSMSGPDN----RGRGRGGFDRGGMS-RGG--RGGGRGGMGAGERGGFNKPGGPMD 346

Query: 380 QGGWTDGG--------SGGGGGYQDG------------GYRDSGFQPGGYHGGH------ 413
           +G   D G        S     Y  G             ++  G        G       
Sbjct: 347 EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 406

Query: 414 ---SSGGYQGGGYGGFQTSSS-------YTGSGYQGGGYQQDNRYQDGGHHGDRGG---- 459
               +G  +G     ++   +       + G  +QG   +     +    +  RGG    
Sbjct: 407 LDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR 466

Query: 460 -GRG-------GRGGRGGRGGRAGQGGGWGG----------RGSQNYHQGGQFEQHFQHG 501
            GRG       G GG GG GG  G+ GG GG          RGS+    GG   QH + G
Sbjct: 467 EGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAG 525

Query: 502 GYQYNHSGFG 511
            +Q  + G G
Sbjct: 526 DWQCPNPGCG 535


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,517,377
Number of Sequences: 37866
Number of extensions: 1655156
Number of successful extensions: 33858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 412
Number of HSP's successfully gapped in prelim test: 420
Number of HSP's that attempted gapping in prelim test: 9383
Number of HSP's gapped (non-prelim): 8297
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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