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Search of human proteins with 56550039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
(3969 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 7957 0.0
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 989 0.0
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 181 2e-44
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 177 2e-43
gi|210032580 SET domain containing 1B [Homo sapiens] 155 6e-37
gi|55741677 SET domain containing 1A [Homo sapiens] 150 2e-35
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 100 2e-20
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 100 2e-20
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 100 2e-20
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 100 4e-20
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 94 4e-18
gi|197313748 SET domain containing 2 [Homo sapiens] 93 6e-18
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 92 1e-17
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 92 1e-17
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 90 5e-17
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-17
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-17
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-17
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 89 9e-17
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 85 2e-15
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 85 2e-15
gi|167736355 mucin 4 isoform a [Homo sapiens] 84 4e-15
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 83 6e-15
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 82 8e-15
gi|83367077 mucin 16 [Homo sapiens] 82 8e-15
gi|91982772 mucin 17 [Homo sapiens] 80 4e-14
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 80 5e-14
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 80 5e-14
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 79 9e-14
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap... 78 2e-13
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 7957 bits (20647), Expect = 0.0
Identities = 3969/3969 (100%), Positives = 3969/3969 (100%)
Query: 1 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAV 60
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAV
Sbjct: 1 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAV 60
Query: 61 AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSA 120
AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSA
Sbjct: 61 AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSA 120
Query: 121 AIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR 180
AIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
Sbjct: 121 AIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR 180
Query: 181 SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKD 240
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKD
Sbjct: 181 SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKD 240
Query: 241 ISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIV 300
ISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIV
Sbjct: 241 ISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIV 300
Query: 301 RRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI 360
RRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
Sbjct: 301 RRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI 360
Query: 361 IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSR 420
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSR
Sbjct: 361 IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSR 420
Query: 421 IIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSS 480
IIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSS
Sbjct: 421 IIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSS 480
Query: 481 SPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS 540
SPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
Sbjct: 481 SPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS 540
Query: 541 RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAS 600
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAS
Sbjct: 541 RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAS 600
Query: 601 TAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPED 660
TAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPED
Sbjct: 601 TAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPED 660
Query: 661 VGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN 720
VGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
Sbjct: 661 VGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN 720
Query: 721 RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSL 780
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSL
Sbjct: 721 RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSL 780
Query: 781 SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT 840
SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT
Sbjct: 781 SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT 840
Query: 841 PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ 900
PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
Sbjct: 841 PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ 900
Query: 901 SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKI 960
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKI
Sbjct: 901 SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKI 960
Query: 961 LIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTD 1020
LIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTD
Sbjct: 961 LIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTD 1020
Query: 1021 KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG 1080
KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
Sbjct: 1021 KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG 1080
Query: 1081 RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKA 1140
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKA
Sbjct: 1081 RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKA 1140
Query: 1141 PQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM 1200
PQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM
Sbjct: 1141 PQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM 1200
Query: 1201 PSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE 1260
PSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
Sbjct: 1201 PSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE 1260
Query: 1261 PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVP 1320
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVP
Sbjct: 1261 PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVP 1320
Query: 1321 KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNIL 1380
KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNIL
Sbjct: 1321 KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNIL 1380
Query: 1381 STLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS 1440
STLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
Sbjct: 1381 STLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS 1440
Query: 1441 GHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNK 1500
GHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNK
Sbjct: 1441 GHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNK 1500
Query: 1501 CRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCA 1560
CRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCA
Sbjct: 1501 CRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCA 1560
Query: 1561 KLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYT 1620
KLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYT
Sbjct: 1561 KLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYT 1620
Query: 1621 CVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESI 1680
CVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESI
Sbjct: 1621 CVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESI 1680
Query: 1681 PSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINS 1740
PSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINS
Sbjct: 1681 PSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINS 1740
Query: 1741 DGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDH 1800
DGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDH
Sbjct: 1741 DGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDH 1800
Query: 1801 NYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPE 1860
NYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPE
Sbjct: 1801 NYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPE 1860
Query: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN
Sbjct: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
Query: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL
Sbjct: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
Query: 1981 IKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDC 2040
IKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDC
Sbjct: 1981 IKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDC 2040
Query: 2041 EDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPT 2100
EDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPT
Sbjct: 2041 EDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPT 2100
Query: 2101 SFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCR 2160
SFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCR
Sbjct: 2101 SFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCR 2160
Query: 2161 PLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYS 2220
PLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYS
Sbjct: 2161 PLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYS 2220
Query: 2221 RNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHL 2280
RNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHL
Sbjct: 2221 RNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHL 2280
Query: 2281 DGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTS 2340
DGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTS
Sbjct: 2281 DGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTS 2340
Query: 2341 RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVK 2400
RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVK
Sbjct: 2341 RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVK 2400
Query: 2401 TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNL 2460
TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNL
Sbjct: 2401 TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNL 2460
Query: 2461 KPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTV 2520
KPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTV
Sbjct: 2461 KPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTV 2520
Query: 2521 KVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSC 2580
KVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSC
Sbjct: 2521 KVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSC 2580
Query: 2581 QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSY 2640
QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSY
Sbjct: 2581 QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSY 2640
Query: 2641 GEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASH 2700
GEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASH
Sbjct: 2641 GEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASH 2700
Query: 2701 NLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPED 2760
NLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPED
Sbjct: 2701 NLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPED 2760
Query: 2761 AGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL 2820
AGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL
Sbjct: 2761 AGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL 2820
Query: 2821 LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG 2880
LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG
Sbjct: 2821 LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG 2880
Query: 2881 LGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT 2940
LGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT
Sbjct: 2881 LGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT 2940
Query: 2941 VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMD 3000
VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMD
Sbjct: 2941 VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMD 3000
Query: 3001 ADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQIS 3060
ADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQIS
Sbjct: 3001 ADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQIS 3060
Query: 3061 NAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTS 3120
NAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTS
Sbjct: 3061 NAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTS 3120
Query: 3121 VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP 3180
VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP
Sbjct: 3121 VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP 3180
Query: 3181 PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP 3240
PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP
Sbjct: 3181 PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP 3240
Query: 3241 SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAP 3300
SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAP
Sbjct: 3241 SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAP 3300
Query: 3301 LLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPG 3360
LLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPG
Sbjct: 3301 LLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPG 3360
Query: 3361 HVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAI 3420
HVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAI
Sbjct: 3361 HVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAI 3420
Query: 3421 TAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQV 3480
TAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQV
Sbjct: 3421 TAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQV 3480
Query: 3481 SNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKT 3540
SNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKT
Sbjct: 3481 SNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKT 3540
Query: 3541 KRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS 3600
KRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS
Sbjct: 3541 KRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS 3600
Query: 3601 QKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESI 3660
QKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESI
Sbjct: 3601 QKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESI 3660
Query: 3661 TEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRML 3720
TEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRML
Sbjct: 3661 TEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRML 3720
Query: 3721 GILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNF 3780
GILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNF
Sbjct: 3721 GILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNF 3780
Query: 3781 LASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHG 3840
LASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHG
Sbjct: 3781 LASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHG 3840
Query: 3841 RGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGN 3900
RGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGN
Sbjct: 3841 RGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGN 3900
Query: 3901 AARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCG 3960
AARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCG
Sbjct: 3901 AARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCG 3960
Query: 3961 AKKCRKFLN 3969
AKKCRKFLN
Sbjct: 3961 AKKCRKFLN 3969
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 989 bits (2557), Expect = 0.0
Identities = 680/1930 (35%), Positives = 943/1930 (48%), Gaps = 298/1930 (15%)
Query: 491 QASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLST-L 549
Q E Q +P+ R + + P Q + + + + ++ + + ++ +
Sbjct: 331 QHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM 390
Query: 550 QSAPQQQTSSSPPPPLLTP---PPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQG 606
A +++ + PPPPL P PPP P S S P PP P++ P LP+ P
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450
Query: 607 KRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASG 666
+ + P T + R P S + +E P + PP TP
Sbjct: 451 EEQEESPPPVVPATCSR-KRGRPPLTPSQRAEREAARAGP--EGTSPPTPTPSTATGGPP 507
Query: 667 FSASGTAASARLFSPLHSGTRFDMH----KRSPLLRAPRFTPSEAHSRIFESVTLPSNRT 722
+ A + F L + +F M + S +++ PR E + + P R
Sbjct: 508 EDSPTVAPKSTTF--LKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRP 565
Query: 723 SAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSI 782
TS +P+ S PR+P+ P TP SI
Sbjct: 566 PITTSPPVPQEP-------APVPSPPRAPT---------------PPSTPVPLPEKRRSI 603
Query: 783 SVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLF---PWF 839
P TF SLT+ P S P P ++SS PL P F
Sbjct: 604 LREP----------TFRWTSLTRELPPPPPAPPPPPAPSPPPAP-ATSSRRPLLLRAPQF 652
Query: 840 TPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEI 899
TP + P L A ++ E + D E E +
Sbjct: 653 TPSEAHLKIYESVLTPPPLG----APEAPEPEPPPADDSPAEPEPRA------------- 695
Query: 900 QSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTK 959
VGR + + ++ K + + +G + L A++T+
Sbjct: 696 --------VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747
Query: 960 ILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMT 1019
+L + L P P L+ + P K + +GS+ L
Sbjct: 748 LLPQA-----------LPPPQPQLQPPPSPQQMPPLE---KARIAGVGSL-----PLSGV 788
Query: 1020 DKRVASLLKKAKAQLCKIEKSKSLK-------------------------------QTDQ 1048
++++ SLLK+AK QL KI++ + K + +
Sbjct: 789 EEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES 848
Query: 1049 PKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSM 1108
+A+ + E+ V+GPRIKHVCR AAVALG+ RA+ P+D+P LSALP +R+ +
Sbjct: 849 VEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQ----DL 904
Query: 1109 GNDDKSSIAGSEDAEP--------LAPPIKPIKPV----TRNKAPQEP-PVKKGRRSR-- 1153
+D SS + +E A P +P T P+ P G++ R
Sbjct: 905 ATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMA 964
Query: 1154 RCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAV 1213
RCG C GC +DCG C NCLDKPKFGG N KKQCC RKC ++ A+ +
Sbjct: 965 RCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIE-----------ARKM 1013
Query: 1214 KKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKS 1271
++ KK +T +VK ++ DS + P S P P++ + PR+ V
Sbjct: 1014 ERLAKKGRT----------IVKTLLPWDSDESPEASPGP-PGPRRGAGAGGPREEV---- 1058
Query: 1272 EEGNVSAPGPESKQATTPASRKSSKQV--SQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
V+ PGPE + + RKS+++ +P+ I + P P+ P++
Sbjct: 1059 ----VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRT--PRE 1110
Query: 1330 KQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPPPVNKQENAGTLNILSTLSNG 1386
+ P PE EQS+ +K +P + +K + K+ P P ++ NG
Sbjct: 1111 NELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPGP------------FASFPNG 1157
Query: 1387 NSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFV 1446
+ KQK P DGVHR+RVDFKEDC+ ENVW MGGL +LTSVP P +VC LCAS G E V
Sbjct: 1158 WTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELV 1216
Query: 1447 YCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH 1506
+CQVCC+PFH FCLEE ERPL + WCCRRCKFCHVCGR+ + +K LLEC +CR++YH
Sbjct: 1217 FCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYH 1276
Query: 1507 PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG 1566
P CLGP+YPT+ T+K++ WIC+ CVRCKSCG+T PGK WD +WS D+SLC C +L+ KG
Sbjct: 1277 PACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWDVEWSGDYSLCPRCTQLYEKG 1335
Query: 1567 NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTE 1626
N+CP+C +CY+D+DYESKMMQC +CD WVH+KCE LSDE YEILS LP+SV YTC C
Sbjct: 1336 NYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAG 1395
Query: 1627 RHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSP 1686
WR AL LQ L+QVL LL+S+ LL Q
Sbjct: 1396 AAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC-------------------- 1435
Query: 1687 EGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPE 1746
GPD KQ P L+ V ++ + G+Y SV F +D+V I+ +S+ G+
Sbjct: 1436 -GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMR--HSEEGETP 1485
Query: 1747 IKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQ 1806
++A +K ++ +E F WF ++W + N G+LPNAVLPPSLDH YAQW+
Sbjct: 1486 DRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-GVLPNAVLPPSLDHVYAQWR 1544
Query: 1807 EREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPG 1866
++E P++P PP P S +D +
Sbjct: 1545 QQE-------------------------PETPESGQPPGDP--SAAFQGKDPAAFSH--- 1574
Query: 1867 IEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVI 1926
+ED RQCALCL YGD + +AGRLLYIGQNEWTHVNCA+WSAEVFE++DGSLKNVH AV
Sbjct: 1575 LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVA 1634
Query: 1927 RGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKG-EV 1985
RG+Q+RCE C KPGATVGCCL+SC SN+HFMC+RA C+F DDKKV+CQ+H DL+ G E+
Sbjct: 1635 RGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEI 1694
Query: 1986 VPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLF 2045
V +GF+V RRV+VDFEGI+ +RKFL GLEP+ I+++IGS+ ID LG L+DLSDCE +LF
Sbjct: 1695 VNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLF 1754
Query: 2046 PIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDINSTVEHDENRTIAHSPTSFT 2103
PIGYQCSR+YWST DAR+RC Y C+I+E RP P EP E EN+TI HSP +
Sbjct: 1755 PIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAE--ENQTIVHSPAPSS 1812
Query: 2104 ESSSKESQN-TAEIISPPSPDR--------PPHSQTSGSCYYHVISKV--PRIRTPSYSP 2152
E E +++ P +P+R PP SGS RI+ P+YSP
Sbjct: 1813 EPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSP 1872
Query: 2153 TQRSPG---CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRI 2209
++R G PLPS GSP+ TH I TVGDP + R R S L+P+ R
Sbjct: 1873 SRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPR----RSRRPSPLAPRPPPSRW 1928
Query: 2210 MS-PMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQR 2268
S P++T +SV T T T E L P + S + +
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGE---------LAPPGPAPSPPPPEDLGPDFED 1979
Query: 2269 TVVTVGNKNSHLDGSSS-----SEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNV 2323
V G + LD ++S ++ A+ + S G+ ++ SS +S V
Sbjct: 1980 MEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPV 2039
Query: 2324 AYPGIPKLAP 2333
P LAP
Sbjct: 2040 TVVSAPGLAP 2049
Score = 487 bits (1254), Expect = e-137
Identities = 267/501 (53%), Positives = 334/501 (66%), Gaps = 36/501 (7%)
Query: 3505 VQASPTSPGGSPSSPSSGQRSASP-----SVPGPTKPKPKTKRFQLPLDKGNGK----KH 3555
V+ P P SP++P+S P V G +P P L L +G +
Sbjct: 2215 VKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
Query: 3556 KVSHLRTSSSEAHIPD----------------QETTSLTSGTGTPGAEAEQQDTASVEQS 3599
+ R S+ P E T G G+ G + T +V
Sbjct: 2275 AIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGV 2334
Query: 3600 SQKEC-GQPAGQVAV------LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQ 3652
+ G+PAG+ + P + + ++ + P + E + + S ++
Sbjct: 2335 LDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEE 2394
Query: 3653 EQKRKESITEKKPKKG---LVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQL 3709
E + + PK+ L FEISS+DGF + AES+E AW++L +KVQEAR +ARL+ L
Sbjct: 2395 EPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHL 2454
Query: 3710 SFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNPHGSARAEV 3768
SF+G++G R+LGI HDAV+FL EQL GA+ C++YKFR+H+ E E PPLNPHG+ARAEV
Sbjct: 2455 SFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEV 2514
Query: 3769 HLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSK 3828
+LRK FDMFNFLAS+HR PE DEEE+EVQL+S RRATS++LPM MRFRHLKKTSK
Sbjct: 2515 YLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSK 2574
Query: 3829 EAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID 3888
EAVGVYRS IHGRGLFCKRNIDAGEMVIEY+G VIRS+ TDKREK+YD KGIGCYMFR+D
Sbjct: 2575 EAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMD 2634
Query: 3889 DSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPI 3948
D +VVDATMHGNAARFINHSCEPNC+SRVI+++GQKHIVIFA+R+I RGEELTYDYKFPI
Sbjct: 2635 DFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPI 2694
Query: 3949 EDASNKLPCNCGAKKCRKFLN 3969
EDASNKLPCNCGAK+CR+FLN
Sbjct: 2695 EDASNKLPCNCGAKRCRRFLN 2715
Score = 88.2 bits (217), Expect = 1e-16
Identities = 196/874 (22%), Positives = 301/874 (34%), Gaps = 244/874 (27%)
Query: 4 SCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAA 63
S R RFP RP GGGGG G RG GA R RV GGG G
Sbjct: 15 SARGRFPGRPRGAGGGGGRGGRG-NGAERVRVALRR-------GGGATG----------- 55
Query: 64 AAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIG 123
PGGA PG D AL +
Sbjct: 56 -----------PGGAE------------------------------PGEDTALLRLLGLR 74
Query: 124 TNLRRFRAVFG----ESGGGGGSG--------------------EDEQFLGFGSDEEV-- 157
LRR R ++ + G G G G ++E+F GF SDE+V
Sbjct: 75 RGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAP 134
Query: 158 ----------RVRSPT-RSPSVKTSPRKP---------------RGRPRSGSDRNSAILS 191
R R+P R KT+P P R R G++R L+
Sbjct: 135 SSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALT 194
Query: 192 DPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIK-----ITHGKDISELPK 246
+ L +++ + + + + + RGRPP P + + + +PK
Sbjct: 195 E-----LLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPK 249
Query: 247 GNKEDSLKKIKR----------------TPSATFQQATKIK----KLRAGKLSPLKSKF- 285
+ +K TP Q + + + R G L P KF
Sbjct: 250 PEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGL-PFVIKFV 308
Query: 286 -KTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTK-- 342
+ K+++G+ + + +G+ E S + PQ+ +G P K
Sbjct: 309 SRAKKVKMGQLSLGLESGQGQGQHEE-----------SWQDVPQRRVGSGQGGSPCWKKQ 357
Query: 343 EDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQ 402
E K + ++ + + ++ + +A++++ A EKE A+L +
Sbjct: 358 EQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAA--------EKEEAKLPPPPLTPP 409
Query: 403 VKNIRQFIMPVVSAISSRIIKTPRRFIEDEDY-DPPIKIARLESTPNSRFSAPSCGSSEK 461
+ + P ++ + P + PP A+ E + P+ S ++
Sbjct: 410 APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKR 469
Query: 462 SSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPEN 521
S + +++R+ T + P + P P +S
Sbjct: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPT---------PSTATGGPPEDSPTVAPKSTTF 520
Query: 522 ESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPP-PPLLTPPPPLQPASSISD 580
N R+ VS RS SR K P++ PP PP + P L+P + S
Sbjct: 521 LKNIRQFIMPVVSARS--SRVIK-------TPRRFMDEDPPKPPKVEVSPVLRPPITTSP 571
Query: 581 HTPWLMPPT-IPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAK 639
P P P +P P++ P+ KR+SILREPTFRWTSL +R P
Sbjct: 572 PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSL--TRELP---------- 619
Query: 640 EGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRA 699
PPP P S A T++ +R LLRA
Sbjct: 620 -------------PPPPAPPPPPAPSPPPAPATSS-----------------RRPLLLRA 649
Query: 700 PRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRS 759
P+FTPSEAH +I+ESV P + + SP EPR+ R+
Sbjct: 650 PQFTPSEAHLKIYESVLTP-----PPLGAPEAPEPEPPPADDSPAEPEPRAVG-----RT 699
Query: 760 GRLSSSELSPLTPPSSVSSSLSISVSPLATSALN 793
LS +P+ V++ + VSP AL+
Sbjct: 700 NHLSLPRFAPV-----VTTPVKAEVSPHGAPALS 728
Score = 37.0 bits (84), Expect = 0.39
Identities = 63/291 (21%), Positives = 107/291 (36%), Gaps = 58/291 (19%)
Query: 2489 DKGLSMPGVPKA--------PPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALK 2540
D + +PG P+ PP++ + + APR + +K+ N S S+ L
Sbjct: 1823 DTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRS----FSGARIKVPNYSPSRRPLG 1878
Query: 2541 E------SSPASPLQIESTSPTE-----PISASENPGDGPVA-QPSPNNTSCQDSQSNNY 2588
SP SP + PT P + P+A +P P+ + +++
Sbjct: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQ 1938
Query: 2589 QNLPVQDRNLML--------------PDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPL 2634
+P + P P P++ G S + +++ F + L
Sbjct: 1939 LRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAAS-L 1997
Query: 2635 YGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE 2694
G + EE + + + G G G D +++ S+ Y +F TV+S+ G
Sbjct: 1998 LGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTSR---YIHFPVTVVSAPGL 2047
Query: 2695 ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNG 2745
A+ P+I QLDGVDDGT+S+ R P G
Sbjct: 2048 APSATPGA---------PRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPG 2089
Score = 35.4 bits (80), Expect = 1.1
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 32/179 (17%)
Query: 1199 WMPSKAYL-QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSARED------ 1251
W PS+ + ++++ + E++ + + S +++ + S + P R
Sbjct: 101 WGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTP 160
Query: 1252 -PAPKKSSSEP-PPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQP 1309
P P+ + P PP+ P ++ EEG QA T R++ PQ
Sbjct: 161 LPPPRLADVAPTPPKTPARKRGEEGT-----ERMVQALTELLRRAQA----------PQA 205
Query: 1310 PTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPV 1368
P + P+ + + +PP +GP + KQ+ V + KP E PPPV
Sbjct: 206 PRSRACEPSTPRRS-----RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKP---EPPPPV 256
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 181 bits (458), Expect = 2e-44
Identities = 107/314 (34%), Positives = 160/314 (50%), Gaps = 6/314 (1%)
Query: 3659 SITEKKPKKGLVFEISSDDGFQICAESI--EDAWKSLTDKVQEARSNARLKQLSFAGVNG 3716
SI EK + V I + I + W + + V R + + QL A + G
Sbjct: 4601 SIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG 4660
Query: 3717 LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEP-PLNPHGSARAEVHLRKSAF 3775
+ G+ AV + E L G + C NY FR+ + P +NP G AR+E K +
Sbjct: 4661 EDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEP---KMSA 4717
Query: 3776 DMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYR 3835
+ F+ H + +A + ++R +K K V + R
Sbjct: 4718 HVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLAR 4777
Query: 3836 SPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDA 3895
S I G GL+ R+I+ MVIEY G +IR+ +++EK Y+S+ G YMFR+D+ V+DA
Sbjct: 4778 SRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDA 4837
Query: 3896 TMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKL 3955
T+ G AR+INHSC PNC + V+ + I+I + R+I +GEEL YDYKF ED +K+
Sbjct: 4838 TLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKI 4897
Query: 3956 PCNCGAKKCRKFLN 3969
PC+CGA CRK++N
Sbjct: 4898 PCHCGAVNCRKWMN 4911
Score = 152 bits (385), Expect = 5e-36
Identities = 85/218 (38%), Positives = 116/218 (53%), Gaps = 8/218 (3%)
Query: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
L P P +D R+C C GD + RLL + + W H+NCALWS EV+E G+L N
Sbjct: 4390 LKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALIN 4449
Query: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
V +A+ RG Q++C FC K GAT GC CT+ YHF C+ C+F DK + C H+
Sbjct: 4450 VELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKP- 4508
Query: 1981 IKGEVVPE-NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGIL----N 2035
KG E + F VFRRV+V + + + E ++ +GS+ +G L
Sbjct: 4509 -KGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHT-FRVGSLIFHTIGQLLPQQM 4566
Query: 2036 DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVE 2073
LFP+GY+ SR+YWST A +RC Y C I E
Sbjct: 4567 QAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEE 4604
Score = 117 bits (293), Expect = 2e-25
Identities = 111/441 (25%), Positives = 177/441 (40%), Gaps = 55/441 (12%)
Query: 1224 EKKDSKESSVVKNVVDSSQKPT-------PSAREDPAPKKSSSEPPPRKPVEEKSEEGNV 1276
EK+ + S + ++DS PT S + + K SS + S+
Sbjct: 723 EKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKADVS 782
Query: 1277 SAPGPESKQATT------PASRKSSKQVSQPALVIPPQPPT-TGPPRKEVPKTTPSEPKK 1329
S+P P S + P++ SS P I P G P K +P P+
Sbjct: 783 SSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRPRS 842
Query: 1330 KQPP--------PPESGPEQSKQKKVAPRPSIPVKQ----KPKEKEKPPPVNKQENAGTL 1377
KQ PP P+ S+ +++ +P K P + AG
Sbjct: 843 KQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG-- 900
Query: 1378 NILSTLSNGNSSKQK-----IPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRV 1432
LS SK K + GV + +D E ++ L + +
Sbjct: 901 --LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQD 958
Query: 1433 VCFLCASSGHV---EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQH 1489
+C +C S G + C C + +H +C+ + + W C C C CG+
Sbjct: 959 MCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLS-KGWRCLECTVCEACGKAT 1017
Query: 1490 QATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQW 1549
+ LL C+ C SYH CL P T P K W C CV C+ CG+T+ G +W
Sbjct: 1018 DPGRLLL-CDDCDISYHTYCLDPPLQTVP---KGGWKCKWCVWCRHCGATSAGLR--CEW 1071
Query: 1550 SHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEI 1609
++++ C CA L + CP+C + Y ++D ++QC +CDRW+H+ C+NL+ E E
Sbjct: 1072 QNNYTQCAPCASLSS----CPVCYRNYREEDL---ILQCRQCDRWMHAVCQNLNTE--EE 1122
Query: 1610 LSNLPESVAYTCVNCTERHPA 1630
+ N+ + + + C C PA
Sbjct: 1123 VENVAD-IGFDCSMCRPYMPA 1142
Score = 113 bits (283), Expect = 3e-24
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 19/211 (9%)
Query: 1434 CFLCASSGHV-EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQAT 1492
C +C S G + + +C C + +H CL+ PL+ W C CK C C + + +
Sbjct: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRA--GWQCPECKVCQNCKQSGEDS 401
Query: 1493 KQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHD 1552
K L+ C+ C YH CL P + PT W C C C CG+ + +QW H+
Sbjct: 402 KMLV-CDTCDKGYHTFCLQPVMKSVPTNG---WKCKNCRICIECGTRS-----SSQWHHN 452
Query: 1553 FSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSN 1612
+C +C + + N CP C KCY + + M+ C C RWVH +C+ +D +E+ +
Sbjct: 453 CLICDNCYQ--QQDNLCPFCGKCY-HPELQKDMLHCNMCKRWVHLECDKPTD--HELDTQ 507
Query: 1613 LPESVAYTCVNCTERHPAEWRLALEKELQIS 1643
L E Y C+ C RL +E++I+
Sbjct: 508 LKEE--YICMYCKHLGAEMDRLQPGEEVEIA 536
Score = 63.9 bits (154), Expect = 3e-09
Identities = 31/84 (36%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 1898 WTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFM 1957
W H C WS V + ++ L NV AV+ G RC FC+ GAT+ CC CT YH+
Sbjct: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
Query: 1958 CSRAKNCVFLDDKKVY--CQRHRD 1979
C+ F D ++ C H D
Sbjct: 310 CAAGAG-TFQDFSHIFLLCPEHID 332
Score = 42.4 bits (98), Expect = 0.009
Identities = 107/469 (22%), Positives = 164/469 (34%), Gaps = 71/469 (15%)
Query: 2906 PVDSSVSSSISAEEQFELPLELPSDL-------SVLTTRSPTVPSQNPSR--LAVISDSG 2956
PV SSS + + + P + P + S+ +RSP V Q A SD
Sbjct: 1948 PVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHF 2007
Query: 2957 EK---RVTITEKS-VASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSV 3012
K R + ++ + S + P L +D P TP M S P GSV
Sbjct: 2008 TKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTP-------MQPPPSSQDPYGSV 2060
Query: 3013 EQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLK 3072
Q +R S + P PI N + ++ P + AV + H
Sbjct: 2061 SQA-------SRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPS 2113
Query: 3073 PATEKLIVVNQ-NMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTL 3131
A + +++ Q Y + P G + + S S + +NT G
Sbjct: 2114 RAFSQPGTISRPTSQDPY---SQPPGTPRPV--VDSYSQSSGTARSNTDPYSQPPGTPRP 2168
Query: 3132 TTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFP-PNISNPPSGLLIGVQP 3190
TT ++P Q+ PS L HS P A P P IS P S QP
Sbjct: 2169 TT-VDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYS------QP 2221
Query: 3191 PPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVS 3250
P P+ +SE R+ ++ V P+ LQ +N+ P+ + P D S
Sbjct: 2222 PATPRPRISEGFTRSSMTRPVLMPNQD------PFLQAAQNR--GPALPGPLVRPPDTCS 2273
Query: 3251 NMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTA 3310
TP P P L D S + S P ++ +P+ P+S +
Sbjct: 2274 Q------TPR--PPGPGLSDTFSRVSPSAARDP------------YDQSPMTPRSQSDSF 2313
Query: 3311 ATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP 3359
T+ ++ + GS ASS+S ++ Q + VP
Sbjct: 2314 GTSQTAHDVADQPRPGSEGSF--CASSNSPMHSQGQQFSGVSQLPGPVP 2360
Score = 40.8 bits (94), Expect = 0.027
Identities = 108/506 (21%), Positives = 169/506 (33%), Gaps = 97/506 (19%)
Query: 906 YPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKG 965
YP S ++ + + KK T +KK T S D TA T + +
Sbjct: 3582 YPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETT 3641
Query: 966 RGNLEKTNLDL------------GPTAPSL-------EKEKTLCLSTPSSSTVKHSTSSI 1006
T +L GP+ P++ E E L S S +T T +
Sbjct: 3642 STPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYAN 3701
Query: 1007 GSMLAQADKLPMTD--KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVR 1064
++ DKL M K L+KA+ + C ++ L++ + K +G +S +
Sbjct: 3702 ----SEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQ 3757
Query: 1065 GPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEP 1124
P + G A L L + +K S + + SI +D
Sbjct: 3758 SP---------PHSAGAPAAKGDSGNELLKHLL--KNKKSSSLLNQKPEGSICSEDDC-- 3804
Query: 1125 LAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNI 1184
NK ++ +G Q G Q+ G C N L K GG
Sbjct: 3805 ----------TKDNKLVEKQNPAEGL------QTLGAQMQGGFG-CGNQLPKTD-GGSET 3846
Query: 1185 KKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSV-----VKNVVD 1239
KKQ SK + KA + +K+ K E+K + SS +K +
Sbjct: 3847 KKQ-------------RSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNN 3893
Query: 1240 SSQKPTPSAREDPAPKKSSSEPPPR--KPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ 1297
S PTP A P P + + EE + + V S + T K +
Sbjct: 3894 LSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLV----SHEVTKTLGPKPFQL 3949
Query: 1298 VSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPP----------------PPESGPEQ 1341
+P + + GP +VP + P+ P Q P S PE
Sbjct: 3950 PFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPES 4009
Query: 1342 SKQKKVAPRPSIP-VKQKPKEKEKPP 1366
+V+ P + VK++P E P
Sbjct: 4010 VVGVEVSRYPDLSLVKEEPPEPVPSP 4035
Score = 38.1 bits (87), Expect = 0.18
Identities = 109/475 (22%), Positives = 172/475 (36%), Gaps = 76/475 (16%)
Query: 411 MPVVSAISSRIIKTPRRFIEDEDYDPPIK-IARLESTPNSRFSAPSCGSSEKSSAASQ-H 468
M V+ + I P E D+ +K IA+L +S+ AP + + AA + +
Sbjct: 1648 MATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRIN 1707
Query: 469 SSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRS 528
QMS+DS + + ++ + P R D+ PL +S + R
Sbjct: 1708 KVQMSNDSMK------------RQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQ 1755
Query: 529 RRYSVSERSFGSRTTKKLSTLQSAPQQQTSSS-PPPPLLTPPPPLQPASSISDHTPWLMP 587
+ S++ T+KL +++ QQQ LL P+S I
Sbjct: 1756 QMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQS------- 1808
Query: 588 PTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPI 647
PL + +P Q K + K S P SS + + KP
Sbjct: 1809 ---PLTPQPGNGNMSPAQSFHKELF---------TKQPPSTPTSTSS-----DDVFVKP- 1850
Query: 648 FDNFRPPPLTPEDVGFASGFSASGTA--ASARLFSPLHSGTR--FDMHKRSPLLRAPRFT 703
PPP P + S + T+ S ++FSP S +R M + ++ PR
Sbjct: 1851 --QAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPR-P 1907
Query: 704 PSEAHSRIFESVTLPSNRTSAG--TSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGR 761
P HS S R SA + + +S+ R ++ + P SP + + S
Sbjct: 1908 PPVGHSF--------SRRNSAAPVENCTPLSSVSRPLQMNETTANRP-SPVRDLCSSSTT 1958
Query: 762 LSSSELSPLTPPSSVSS-----SLSISVSPLAT--SALNPTFTFPSHSLTQSGESAEKNQ 814
+ P P V + SL +S SP+ + +A P S T+ A+ Q
Sbjct: 1959 NNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQ 2018
Query: 815 RPR--------KQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKD 861
R R T AP + TP+ P P SQ G + +A LS D
Sbjct: 2019 RQRIPDSYARPLLTPAPLDSGPGPFKTPMQP--PPSSQDPYG-SVSQASRRLSVD 2070
Score = 38.1 bits (87), Expect = 0.18
Identities = 53/246 (21%), Positives = 92/246 (37%), Gaps = 16/246 (6%)
Query: 1129 IKPIKPVTRNKAPQE--PPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGR---N 1183
+K I + R + QE P V+K R +R + Q+ D D R
Sbjct: 1675 VKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSE 1734
Query: 1184 IKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK 1243
+ K K R+ ++ Q + +++++K K E K + K+ ++ + S
Sbjct: 1735 LFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQF-GSQHL 1793
Query: 1244 PTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL 1303
S + P+ S P+ + GN+S K+ T + S +
Sbjct: 1794 LVQSGSDTPSSGIQS-------PLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDV 1846
Query: 1304 VIPPQPPTTGPPRKEVP-KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEK 1362
+ PQ P P +P + + S+ + QPP P+ S + P P P K
Sbjct: 1847 FVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSR-PPSPMDPY-AKMVGT 1904
Query: 1363 EKPPPV 1368
+PPPV
Sbjct: 1905 PRPPPV 1910
Score = 38.1 bits (87), Expect = 0.18
Identities = 58/247 (23%), Positives = 94/247 (38%), Gaps = 49/247 (19%)
Query: 3441 SPSGEADEHYQLQHVNQLLASKTGIHSSQRDL-----------DSASGPQVSNFTQTVDA 3489
+P +A H L KT +H DL SA+ Q S D
Sbjct: 2851 TPCSQASAHSDLND-----GEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDV 2905
Query: 3490 PNSMGLEQNKALSSAVQASPTS------PGGSPSSPSSGQRSASPSVPGPTKPK---PKT 3540
NS G+ + + S++ A+ S P GSP P+ ASPS + P P
Sbjct: 2906 INSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTL---PASPSNHVSSLPPFIAPPG 2962
Query: 3541 KRFQLPLDKGNGKKHKVSHLRTSSSEAH---IPDQETTSLTSGTGTPGAEAEQQDTASVE 3597
+ ++ +V+H+ + + + IP Q T + + GTG P + Q
Sbjct: 2963 RVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQ----TS 3018
Query: 3598 QSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRK 3657
QS P Q ++P+ QN P +EE+ PL+L +Q+R+
Sbjct: 3019 QSGTSSMSGP--QQLMIPQTLAQQN------RERPLLLEEQ------PLLLQDLLDQERQ 3064
Query: 3658 ESITEKK 3664
E +++
Sbjct: 3065 EQQQQRQ 3071
Score = 35.4 bits (80), Expect = 1.1
Identities = 50/210 (23%), Positives = 75/210 (35%), Gaps = 29/210 (13%)
Query: 3478 PQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSA---SPSVPGPT 3534
P S+ Q + +Q+ S A P +P + SS GQ S S PG T
Sbjct: 3527 PNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGST 3586
Query: 3535 KPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPD--------------QETTSLTSG 3580
+ + +P +KG K+ + + P ETTS T
Sbjct: 3587 QSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTS-TPA 3645
Query: 3581 TGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV-----LPEVQVTQNPANEQESAEPKTV 3635
TP +Q D SVE AGQ+ LP +Q N+Q A
Sbjct: 3646 VSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANS--- 3702
Query: 3636 EEEESNFSSPLMLWLQQEQKRKESITEKKP 3665
E ++ + +P +E K +++ TE P
Sbjct: 3703 EVDKLSMETPAK---TEEIKLEKAETESCP 3729
Score = 33.5 bits (75), Expect = 4.3
Identities = 144/617 (23%), Positives = 220/617 (35%), Gaps = 91/617 (14%)
Query: 2474 MGQRPCNNVSSDKIGDKGLSMPGVPK--APPMQVEGSAKELQAPRKRTVKVTLTPLKMEN 2531
MG RP G G +MP + PP Q++GS Q R +V + PL N
Sbjct: 2473 MGMRPHGFRFGFPGGSHG-TMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMP-RPL---N 2527
Query: 2532 ESQSKNAL---KESSPAS-PLQIESTSPTEPISASENPGDGPVAQP--SPNNTSCQDSQS 2585
SQ N + + SP S P+Q + I DG P +P + + S +
Sbjct: 2528 NSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSN 2587
Query: 2586 NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVR-SYGEED 2644
+ N + PD P P+ RR + N L V S E+
Sbjct: 2588 LRHGNF------IPRPDFPGPRHTDPM-----RRPPQGLPNQLPVHPDLEQVPPSQQEQG 2636
Query: 2645 IPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGG-EERLASHN-L 2702
+SSS + G+ A LSTS + N T S G EE+L S +
Sbjct: 2637 HSVHSSSMVMRTLNHPLGGEFSEAP-LSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPS 2695
Query: 2703 FREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK-------- 2754
+E + DL + D +DD + ++ K ++ + E NL
Sbjct: 2696 VKELDVKDLEGVEVKD-LDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEF 2754
Query: 2755 -----IDRPEDAGEKEHVTKSSVGHKNEPKMDN-CHSVSRVKTQGQDSLEAQLSSLESSR 2808
D D G+K+ + + + K+DN C SV K + Q++ LS S +
Sbjct: 2755 DIIAYTDPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKE-QENKTLVLSDKHSPQ 2813
Query: 2809 RVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPE 2868
+ T T K + + N+++ N ++ N+ +TP QA S
Sbjct: 2814 KKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNV-----------DTPCSQASAHSD- 2861
Query: 2869 SSSSELLNLGEGLGLD----------SNREKDMGLFEVF--SQQLPTTEPVDS------- 2909
LN GE L +NRE V S QLP + ++S
Sbjct: 2862 ------LNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGST 2915
Query: 2910 SVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRL-AVISDSGEKRVTITEKSVA 2968
V SS+ A E+ + PS S P PS + S L I+ G +V
Sbjct: 2916 PVLSSLLANEKSDNSDIRPSG-SPPPPTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVT 2974
Query: 2969 SSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSST 3028
+ S GV P I G +H + + G +Q T + S
Sbjct: 2975 VVSRVNHVFSQGVQVNP-------GLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSG 3027
Query: 3029 PGLQVPVSPTVPIQNQK 3045
P Q+ + T+ QN++
Sbjct: 3028 P-QQLMIPQTLAQQNRE 3043
Score = 32.7 bits (73), Expect = 7.4
Identities = 32/154 (20%), Positives = 58/154 (37%), Gaps = 9/154 (5%)
Query: 1222 TSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGP 1281
TS+ S+ + VVDS + + +AR + P P V+ S++ P
Sbjct: 2126 TSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST 2185
Query: 1282 ESKQATTPASRKSSKQ-------VSQPALVIP-PQPPTTGPPRKEVPKTTPSEPKKKQPP 1333
++ TP + + +P + +P QPP T PR T S + P
Sbjct: 2186 QTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMP 2245
Query: 1334 PPESGPEQSKQKKVA-PRPSIPVKQKPKEKEKPP 1366
+ + ++ + A P P + + +PP
Sbjct: 2246 NQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPP 2279
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 177 bits (448), Expect = 2e-43
Identities = 98/290 (33%), Positives = 154/290 (53%), Gaps = 16/290 (5%)
Query: 3685 SIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK 3744
S + W + + V R A + +L + G + G+ AV+ + E L G + C+NY
Sbjct: 5259 SPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYL 5318
Query: 3745 FRFHKPEEANEP-PLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL 3803
FR+ + P +NP G AR+E + + +++P N +
Sbjct: 5319 FRYGRHPLMELPLMINPTGCARSEPK-----------ILTHYKRPHTLNSTSMSKAYQST 5367
Query: 3804 KSARRATSMDLPM----PMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYA 3859
+ T ++R L+ K V + RS I G GL+ ++++ MVIEY
Sbjct: 5368 FTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYI 5427
Query: 3860 GNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVIN 3919
G +IR+ ++REK Y+ + G YMFRI++ V+DAT+ G AR+INHSC PNC + V+
Sbjct: 5428 GTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVT 5487
Query: 3920 IDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN 3969
D + I+I + R+I +GEELTYDY+F ED +K+PC+CGA CRK++N
Sbjct: 5488 FDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
Score = 147 bits (371), Expect = 2e-34
Identities = 78/219 (35%), Positives = 115/219 (52%), Gaps = 10/219 (4%)
Query: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
L P D R+C C GD + + RLL + + W H+NCALWS EV+E G+L N
Sbjct: 5020 LRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMN 5079
Query: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
V +A+ RG +C CQ+ GAT C C + YHF C+ C+F DK + C H+
Sbjct: 5080 VEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHK-- 5137
Query: 1981 IKGEVVPE-NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMM-IGSMTIDCLGIL--ND 2036
IKG E + F VFRRV+++ + + + E +HM +G + +G L +
Sbjct: 5138 IKGPCEQELSSFAVFRRVYIERDEVKQIASIIQ--RGERLHMFRVGGLVFHAIGQLLPHQ 5195
Query: 2037 LSDCED--KLFPIGYQCSRVYWSTTDARKRCVYTCKIVE 2073
++D L+P+GY+ +R+YWS +RC Y C I E
Sbjct: 5196 MADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGE 5234
Score = 110 bits (275), Expect = 3e-23
Identities = 61/197 (30%), Positives = 95/197 (48%), Gaps = 24/197 (12%)
Query: 1433 VCFLCASSGHV---EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQH 1489
+C +C S G + C C + +H +C+ + L+ W C C C VCG+
Sbjct: 1379 MCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVM-LLKGWRCVECIVCEVCGQAS 1437
Query: 1490 QATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQW 1549
++ LL C+ C SYH CL P T P K W C CV C CG+ +P G+ +W
Sbjct: 1438 DPSRLLL-CDDCDISYHTYCLDPPLLTVP---KGGWKCKWCVSCMQCGAASP--GFHCEW 1491
Query: 1550 SHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENL--SDEMY 1607
+ ++ C CA L CP+C Y ++D ++QC C+RW+H+ CE+L D++
Sbjct: 1492 QNSYTHCGPCASLVT----CPICHAPYVEEDL---LIQCRHCERWMHAGCESLFTEDDVE 1544
Query: 1608 EILSNLPESVAYTCVNC 1624
+ + CV+C
Sbjct: 1545 QAADE-----GFDCVSC 1556
Score = 74.7 bits (182), Expect = 2e-12
Identities = 94/447 (21%), Positives = 157/447 (35%), Gaps = 78/447 (17%)
Query: 1434 CFLCASSGHV-EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQAT 1492
C +C G + + +C C +H CL+ + W C CK C C + +
Sbjct: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDT--ALTARKRAGWQCPECKVCQACRKPGNDS 286
Query: 1493 KQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHD 1552
K L+ C C YH CL P P W C C C++CG+ + +++W +
Sbjct: 287 KMLV-CETCDKGYHTFCLKPPMEELPAHS---WKCKACRVCRACGAGSAELNPNSEWFEN 342
Query: 1553 FSLCHDCAKLFAKG---------NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLS 1603
+SLCH C K A+G P+C + + ++ +
Sbjct: 343 YSLCHRCHK--AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDE---------------P 385
Query: 1604 DEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRY 1663
D +Y P+ T + E P + + + L+ L A LN
Sbjct: 386 DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEE-------- 437
Query: 1664 RQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSV 1723
PP+ E+ S P SP P PP + +S ++ P S
Sbjct: 438 MPLLPPPE---ESPLSPPPEESPTSP-PPEASRLSPPPEELP---------------ASP 478
Query: 1724 LEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVS 1783
L + + + ++ + S PE + +S P+ +++S P +
Sbjct: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPPES---------SPFSPLEESPLSPPEESP 527
Query: 1784 SNSGMLPNAVLPPSLDHNYAQWQER-----EENSHTEQPPLMKKIIPAPKPKGPGEPDSP 1838
+ + PP ++E E T PP ++ P P+ P
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 1839 TPLHPPTPPILSTDRSREDSPELNPPP 1865
+P+ PP P E+SP L+PPP
Sbjct: 588 SPMSPP-PEASRLFPPFEESP-LSPPP 612
Score = 54.3 bits (129), Expect = 2e-06
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 1894 GQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSN 1953
G + W H CA WSA V+ + L V A+ G RC C + GA++ C C
Sbjct: 133 GGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCPRL 192
Query: 1954 YHFMCSRAKNCVFLDDK--KVYCQRHRD 1979
YHF C+ A FL K ++ C H +
Sbjct: 193 YHFPCATASGS-FLSMKTLQLLCPEHSE 219
Score = 53.1 bits (126), Expect = 5e-06
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 2/140 (1%)
Query: 1230 ESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTP 1289
ESS + +S P + PA + S PP P+ EE +S P E + P
Sbjct: 508 ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567
Query: 1290 ASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKV 1347
+ + S + + PP+ PP + P E PPP ES P +
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627
Query: 1348 APRPSIPVKQKPKEKEKPPP 1367
P P+ P+E PP
Sbjct: 628 PPPEDSPMSPPPEESPMSPP 647
Score = 51.6 bits (122), Expect = 2e-05
Identities = 37/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 1244 PTPSAREDPAPKKSSSEPPPRK-PVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPA 1302
P ++R P P++S PPP + P+ E + P ES + P S
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 1303 LVIPPQPPTTGPPRKEVPKTTPSEPKKKQP--------PPPESGP--EQSKQKKVAPRPS 1352
L PP+ PP +E P + P E + P PPPE P ++ +P P
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685
Query: 1353 IPVKQKPKEKE--KPPP 1367
P E PPP
Sbjct: 686 ASRLSPPPEDSPTSPPP 702
Score = 50.4 bits (119), Expect = 3e-05
Identities = 81/379 (21%), Positives = 139/379 (36%), Gaps = 53/379 (13%)
Query: 553 PQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPM-QGKRKSI 611
P T PPL P P P S + +PP + PF +P Q +S
Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCA------LPPRSLPSDPFSRVPASPQSQSSSQSP 2424
Query: 612 LREPTFRWTSLKHSRSEPQYFSSAKYAK---EGLIRKPIFDNFRPPPLTPEDVGFASGFS 668
L + S P++ S Y++ R P +PP P +V F +G
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSL 2484
Query: 669 ASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRF-----------TPSEAHSRIFESVTL 717
A + + + L +G ++H + P + P F TPS ++V
Sbjct: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544
Query: 718 PSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVS 777
PS + + P +P+S ++++ T + S S L PSS S
Sbjct: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLG----PSSGS 2600
Query: 778 SSLSISVSPLATSALNP------TFTFPSHSLTQ-SGESAEKNQRPRKQTSAPAEPFSSS 830
+ S +SPL ++ P + + SH +Q SG ++ +R T + ++
Sbjct: 2601 TGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAE 2660
Query: 831 SPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRK 890
P P + SQTE +EK + R+R RE + +
Sbjct: 2661 LPGTQDPGMSGLSQTE---------------------LEKQRQRQRLRELLIRQQIQRNT 2699
Query: 891 EKRKKGSEIQSSSALYPVG 909
+++K + ++ A+ P G
Sbjct: 2700 LRQEKETAAAAAGAVGPPG 2718
Score = 50.1 bits (118), Expect = 4e-05
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 16/128 (12%)
Query: 1244 PTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL 1303
P + P P++S + PPP E +S P E + P + S+ + + L
Sbjct: 443 PPEESPLSPPPEESPTSPPP--------EASRLSPPPEELPASPLPEALHLSRPLEESPL 494
Query: 1304 VIPPQPPTTGPPRKEVPKTTPSEPKKKQP--PPPESGPEQSKQKKVAPRPSIPVKQKPKE 1361
PP+ PP P+++P P ++ P PP ES P + + ++P P P E
Sbjct: 495 SPPPEESPLSPP----PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
Query: 1362 KE--KPPP 1367
+ PPP
Sbjct: 551 ESPLSPPP 558
Score = 49.3 bits (116), Expect = 8e-05
Identities = 37/134 (27%), Positives = 48/134 (35%), Gaps = 9/134 (6%)
Query: 1243 KPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAP--GPESKQATTPASRKSSKQVSQ 1300
+P + P P++S PPP EE +S P P S TP S
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS 546
Query: 1301 PA-----LVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKVAPRPSI 1353
P L PP+ T PP + + P E PPP ES P + P
Sbjct: 547 PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606
Query: 1354 PVKQKPKEKEKPPP 1367
P+ P+E PP
Sbjct: 607 PLSPPPEESPLSPP 620
Score = 48.5 bits (114), Expect = 1e-04
Identities = 35/128 (27%), Positives = 49/128 (38%), Gaps = 5/128 (3%)
Query: 1244 PTPSAREDPAPKKSSSEPPPRK-PVEEKSEEGNVSAPGPESKQATTPASRKS-SKQVSQP 1301
P P P+ S PPP + P+ EE +S P PE+ + P S +
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP-PEASRLFPPFEESPLSPPPEES 615
Query: 1302 ALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKVAPRPSIPVKQKP 1359
L PP+ PP ++ P + P E PPP S P + P P+ P
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 1360 KEKEKPPP 1367
+E PP
Sbjct: 676 EESPTSPP 683
Score = 48.5 bits (114), Expect = 1e-04
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 1244 PTPSAREDPAPKKSSSEPPPR-KPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPA 1302
P + P P+ S PPP P+ EE +S P S+ + P + S +
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
Query: 1303 LVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES----GPEQSKQK-KVAPRPSIPVKQ 1357
L PP+ T PP + + P E PPP +S PE S + P +P+ +
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 1358 KPK 1360
+P+
Sbjct: 731 EPQ 733
Score = 45.8 bits (107), Expect = 8e-04
Identities = 92/373 (24%), Positives = 136/373 (36%), Gaps = 41/373 (10%)
Query: 484 VDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTT 543
++ ++ +EE+ +LP ++P PP SP E+ SR E S
Sbjct: 426 LEPQLEAPLNEEMPLLPPPE-ESPLSPPPEESPTSPPPEA----SRLSPPPEELPASPLP 480
Query: 544 KKLSTLQSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAST 601
+ L S P +++ SPPP L+PPP P S + + P + P SP PA
Sbjct: 481 EALHL--SRPLEESPLSPPPEESPLSPPPESSPFSPLEE-----SPLSPPEESPPSPALE 533
Query: 602 APMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDV 661
P+ ++ P F + L P+ ++ + + P ++ PP PE+
Sbjct: 534 TPLSPPPEASPLSPPFEESPLS---PPPEELPTSPPPEASRLSPPPEESPMSPP--PEES 588
Query: 662 GFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAP---RFTPSEAHSRIF----ES 714
+ AS RLF P + SPL P R +P S + ES
Sbjct: 589 PMSPPPEAS------RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Query: 715 VTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLS-SSELSPLTPP 773
P S S V +R SP+ P S + RLS E SP +PP
Sbjct: 643 PMSPPPEVSR-LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP 701
Query: 774 SSVSSSL-----SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFS 828
S + S+ PL S L P P L E + RP + +P
Sbjct: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEP--QLCPRSEGPHLSPRPEEPHLSPRPEEP 759
Query: 829 SSSPTPLFPWFTP 841
SP P +P
Sbjct: 760 HLSPQAEEPHLSP 772
Score = 45.4 bits (106), Expect = 0.001
Identities = 60/250 (24%), Positives = 96/250 (38%), Gaps = 29/250 (11%)
Query: 1121 DAEPLAPPIK--PIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPK 1178
+A PL+PP + P+ P + P PP + R S + P PE+ + + P
Sbjct: 541 EASPLSPPFEESPLSPPPE-ELPTSPPPEASRLSPPPEESPMSPPPEE-----SPMSPPP 594
Query: 1179 FGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV 1238
R + L P ++ L +A + + +ES +
Sbjct: 595 EASRLFPPF-----EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
Query: 1239 DSSQKPTPS-AREDPAPKKSSSEPPPRK----PVEEKSE-----EGNVSAPGPESKQATT 1288
S P P +R P P++S PPP + P E S E + ++P PE A+
Sbjct: 650 VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 1289 PA--SRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESG--PEQSKQ 1344
P S S P L +P +P PR E P +P + P PE Q+++
Sbjct: 710 PPEDSLMSLPLEESPLLPLPEEPQLC--PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE 767
Query: 1345 KKVAPRPSIP 1354
++P+P P
Sbjct: 768 PHLSPQPEEP 777
Score = 45.4 bits (106), Expect = 0.001
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%)
Query: 1229 KESSVVKNVVDSSQKPTPSARE----------DPAPKKSSSEPPPRKPVEEKSEEGNVSA 1278
+ES + +S P P A P P++S PPP E + +
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 1279 PGPESKQATTP--ASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPE 1336
P PE + P SR S V P + P + PP +E P + P E + PPP +
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS-PPPEESPTSPPPEASRLSPPPED 695
Query: 1337 SGPEQSKQKKVAPRP------SIPVKQKP 1359
S + A P S+P+++ P
Sbjct: 696 SPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Score = 43.1 bits (100), Expect = 0.005
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 1241 SQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKS-SKQVS 1299
S++P S R + + E PP P EK E P PE P S S +
Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
Query: 1300 QPALVIPPQPPTTGPPRKEVPKTTPSEPK---KKQPPPPESGP 1339
+PAL P +PP + P +E+P + EP + PP P P
Sbjct: 897 EPALSEPGEPPLS-PLPEELPLSPSGEPSLSPQLMPPDPLPPP 938
Score = 40.8 bits (94), Expect = 0.027
Identities = 41/177 (23%), Positives = 62/177 (35%), Gaps = 23/177 (12%)
Query: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTD 489
E+ PP + +RL P ++P + H S+ +S S P +
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASPL--------PEALHLSRPLEESPLSPPPEESPLSP 505
Query: 490 SQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTL 549
S L E PE PP P ++P + + E
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL----------- 554
Query: 550 QSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPPTIP-LASPFLPASTAP 603
S P ++ +SPPP L+PPP P S + +P PP L PF + +P
Sbjct: 555 -SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610
Score = 40.4 bits (93), Expect = 0.035
Identities = 55/254 (21%), Positives = 85/254 (33%), Gaps = 47/254 (18%)
Query: 1151 RSRRCGQCPGCQVPEDC-----------------GVCTNCLDKP--KFGGRNIKKQCCKM 1191
R R QCP C+V + C G T CL P + + K + C++
Sbjct: 263 RKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRV 322
Query: 1192 -RKC--------QNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQ 1242
R C N +W + + + KA + +T + + V
Sbjct: 323 CRACGAGSAELNPNSEWFENYSLCHRCHKA-----QGGQTIRSVAEQHTPVCSRFSPPEP 377
Query: 1243 KPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATT--PASRKSSKQVSQ 1300
TP+ D +P + +E PGP +A A + Q+
Sbjct: 378 GDTPTDEPDALYVACQGQPKGGHVTSMQPKE-----PGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 1301 P-----ALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPE--SGPEQSKQKKVAPRPSI 1353
P L+ PP+ PP +E P + P E + PPP E + P P
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
Query: 1354 PVKQKPKEKEKPPP 1367
P+ P+E PP
Sbjct: 493 PLSPPPEESPLSPP 506
Score = 39.3 bits (90), Expect = 0.079
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 13/134 (9%)
Query: 1260 EPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEV 1319
E P +P + S NVS + +Q + P + S S P P PPT P E+
Sbjct: 4882 ESPAPEPPTQHSYTYNVS--NLDVRQLSAPPPEEPSPPPS-PLAPSPASPPTE--PLVEL 4936
Query: 1320 PKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENA--GTL 1377
P +EP P P S PE ++ K A P + E +PP + K + L
Sbjct: 4937 PTEPLAEPPVPSPLPLASSPESARPKPRARPP------EEGEDSRPPRLKKWKGVRWKRL 4990
Query: 1378 NILSTLSNGNSSKQ 1391
+L T+ G+ ++
Sbjct: 4991 RLLLTIQKGSGRQE 5004
Score = 38.5 bits (88), Expect = 0.13
Identities = 90/389 (23%), Positives = 133/389 (34%), Gaps = 70/389 (17%)
Query: 3026 SSTPGLQVPVSPTVPIQNQKYVPNSTDSPGP-----SQISNAAVQTTPPHLKPATEKLIV 3080
S T L P P + Q PGP + + T L+ + ++
Sbjct: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Query: 3081 VN---QNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNP 3137
N +++ P Q + +++Q + +V TP E T P+ G L G P
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQT-SPLQGLL----GCQP 4261
Query: 3138 SLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIG-----VQPPP 3192
L FP G L A + PP + PP L G V P P
Sbjct: 4262 QLGG----FPGPQTG--------PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP 4309
Query: 3193 DPQLLVSESSQRTDLSTTVATPSSGL---KKRPISRLQTRKNKKLAPSSTPSNIAPSDVV 3249
P S Q + + +PSS L + P + T K + P ++P+
Sbjct: 4310 PP-----SSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364
Query: 3250 SNMTLI-----------NFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEP 3298
TL N +Q P SL+ G L+ + + VP + S EP
Sbjct: 4365 LADTLFSKGLGPWDPPDNLAETQKPEQSSLVP-GHLDQVNGQVVPEASQLSIKQEPREEP 4423
Query: 3299 APLLPQSV----GGTAATAAGTSTISQDTSHLTSG---SVSGLASSSSVLNVVSMQTTTT 3351
L QSV G A GTS +HL S +G +L ++Q +T
Sbjct: 4424 CALGAQSVKREANGEPIGAPGTS------NHLLLAGPRSEAGHLLLQKLLRAKNVQLSTG 4477
Query: 3352 PTSS---ASVPGHVTL----TNPRLLGTP 3373
S A + GH+ +L GTP
Sbjct: 4478 RGSEGLRAEINGHIDSKLAGLEQKLQGTP 4506
Score = 38.1 bits (87), Expect = 0.18
Identities = 66/313 (21%), Positives = 116/313 (37%), Gaps = 33/313 (10%)
Query: 1090 MPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIK--PIKPVTRNKAPQEPPVK 1147
+P +S L E LS ++S + +A L+PP + P P + +P PP +
Sbjct: 656 LPVVSRLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPED-SPASPPPE 712
Query: 1148 KGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQ 1207
S + P +PE+ +C P+ G ++ + + +L P + +L
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLC------PRSEGPHLSPR----PEEPHLSPRPEEPHLS 762
Query: 1208 KQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSARE-DPAPKKSSSEPPPRKP 1266
QA+ + + +E + P P P ++ P P +P
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP 822
Query: 1267 -VEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVI----PPQPPTTGPPRKEVPK 1321
+ + EE ++S E + P S ++ +P L PP+ P P +E+P
Sbjct: 823 CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL 882
Query: 1322 TTP----------SEPKKKQP-PPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNK 1370
P EP +P PP S + + PS+ + P + PPP++
Sbjct: 883 FPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD-PLPPPLSP 941
Query: 1371 QENAGTLNILSTL 1383
A LS L
Sbjct: 942 IITAAAPPALSPL 954
Score = 38.1 bits (87), Expect = 0.18
Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 18/129 (13%)
Query: 490 SQASEEIQVLPE-ERSDTPEVHPP--LPISQSPE-NESNDRRSRRYSVSERSFGSRTTKK 545
S EE+ + P E S +P++ PP LP SP + E FG++
Sbjct: 909 SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSD 968
Query: 546 LSTLQSAPQQQTSSSPP-----------PPLLTPPPPLQPASSISDHTPWLMPPTIPLAS 594
+ +AP +T SPP PP++ PP P S + +P LM P P S
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPP---SPGSPVGPASPILMEPLPPQCS 1025
Query: 595 PFLPASTAP 603
P L S P
Sbjct: 1026 PLLQHSLVP 1034
Score = 37.7 bits (86), Expect = 0.23
Identities = 71/295 (24%), Positives = 96/295 (32%), Gaps = 34/295 (11%)
Query: 549 LQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASP---FLPASTAPMQ 605
+Q PQ + + PLL PPP P S + +P PP SP LPAS P
Sbjct: 424 VQLEPQLEAPLNEEMPLL-PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA 482
Query: 606 GKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFAS 665
L E + S P S F PL+P +
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSP-------------FSPLEESPLSPPEE---- 525
Query: 666 GFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLP-SNRTSA 724
S A L P + + SPL P P+ P + S
Sbjct: 526 --SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
Query: 725 GTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISV 784
S +S ++F P P SP S +S LSP PP S
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP--PPEDSPMSPPPEE 641
Query: 785 SPLA----TSALNPTFTFPSHS-LTQSGESAEKNQRPRKQTSAPAEPFSSSSPTP 834
SP++ S L+P P S L+ E + + P + ++P S SP P
Sbjct: 642 SPMSPPPEVSRLSP---LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Score = 37.4 bits (85), Expect = 0.30
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 10/119 (8%)
Query: 1250 EDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTP-ASRKSSKQVSQPALVIPPQ 1308
E P ++ PPP EE +S P ES + P ASR S PA +P +
Sbjct: 431 EAPLNEEMPLLPPP--------EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP-E 481
Query: 1309 PPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
P +E P + P E PPP S ++ ++P P + PPP
Sbjct: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Score = 36.2 bits (82), Expect = 0.67
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 559 SSPPPPLLTPPP-PLQPASSISDHTPWLMPPTIPLASP----FLPASTAPMQGKRKSILR 613
S+PPP +PPP PL P+ + P + PT PLA P LP +++P + K R
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 614 EP 615
P
Sbjct: 4967 PP 4968
Score = 35.8 bits (81), Expect = 0.87
Identities = 126/575 (21%), Positives = 187/575 (32%), Gaps = 101/575 (17%)
Query: 3007 PPCGSVEQGHGNNQDLTRNSS--TPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAV 3064
PP ++ ++ D+ R S P Q P++P + Q P S + P + +
Sbjct: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP----RPQPPPPESCCALPPRSLPSDPF 2408
Query: 3065 QTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLG- 3123
P P ++ +PL P+ VT + Q S PS ++
Sbjct: 2409 SRVPA--SPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466
Query: 3124 -----PMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPN-I 3177
P + G FP+A LP LH A S PPN +
Sbjct: 2467 HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA----LPAGPAGELH---AKVPSGQPPNFV 2519
Query: 3178 SNPPSGLLIGVQPPPD---PQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKL 3234
+P +G +G P PQ V E S + + P G+ N
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQA-VGEPSLKPPVPQPGLPPPHGI------------NSHF 2566
Query: 3235 APSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM 3294
P T P + NF PS P PS G S P+++
Sbjct: 2567 GPGPTLGK--PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP------- 2617
Query: 3295 YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTS 3354
PAP G + G S S TS + G SS+ T
Sbjct: 2618 --PPAP-----DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL--------ATAELP 2662
Query: 3355 SASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQP---------VALP----- 3400
PG L+ L + LLI+ Q ++ + V P
Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722
Query: 3401 -PSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLL 3459
PSS F QL QTP A SS+ LP ++ +G S +D+
Sbjct: 2723 EPSSPAFEQLSRGQTP-FAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPP--- 2778
Query: 3460 ASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNK-------------ALSSAVQ 3506
A+ + + + R L S F Q P S+ L+Q + ++ A+
Sbjct: 2779 ATPSSMDVNSRQLVGGS----QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMS 2834
Query: 3507 AS-PTSPGGSPSSPSSGQRSA--SPSVPGPTKPKP 3538
A P++PG + G A S +PGP +P P
Sbjct: 2835 ARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869
Score = 35.4 bits (80), Expect = 1.1
Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 23/125 (18%)
Query: 1262 PPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPP--QPPTTG---PPR 1316
P VE +S + P QA P S S + +P P QPP T PP
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAP-SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 1317 KE-----VPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR----------PSIPVKQKPKE 1361
E P++ PS+P + P P+S + S Q + PR P P Q P
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQS--QSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449
Query: 1362 KEKPP 1366
+PP
Sbjct: 2450 YSRPP 2454
Score = 35.0 bits (79), Expect = 1.5
Identities = 44/184 (23%), Positives = 64/184 (34%), Gaps = 38/184 (20%)
Query: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTD 489
E+ PP + + + P + P S S + ++SR S P D+
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 490 SQASEEIQVLPEERSDTPEVHPPLPISQ--SPENESNDRRSRRYSVSERSFGSRTTKKLS 547
E P E S PLP+ SP E +
Sbjct: 637 PPPEESPMSPPPEVSRL----SPLPVVSRLSPPPEESP---------------------- 670
Query: 548 TLQSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPP-----TIPL-ASPFLPA 599
S P +++ +SPPP L+PPP P S + +P PP ++PL SP LP
Sbjct: 671 --LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728
Query: 600 STAP 603
P
Sbjct: 729 PEEP 732
Score = 33.1 bits (74), Expect = 5.6
Identities = 69/314 (21%), Positives = 100/314 (31%), Gaps = 52/314 (16%)
Query: 3367 PRLLGTPDI------GSISNLLIKASQQSLG--IQDQPVALPPSSGMFPQLGTSQTPSTA 3418
P LL P + GS++ L+ Q L +Q+ PP G Q G P
Sbjct: 4131 PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQG-LPGVG 4189
Query: 3419 AITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT--------------- 3463
+ + Q G+ A +P Q Q + LL +
Sbjct: 4190 IMPTVGQL----RAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
Query: 3464 ---------GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASP----- 3509
G+ Q L GPQ + P G + A A+ P
Sbjct: 4246 PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
Query: 3510 --TSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEA 3567
T P SP P + SPS PT+ + P K G + R S + A
Sbjct: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP--KPQGPTLEPPPGRVSPAAA 4363
Query: 3568 HIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS--QKECGQPAGQVA-VLPEVQVTQNPA 3624
+ D T + G G +T EQSS Q GQV ++ + Q P
Sbjct: 4364 QLAD---TLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPR 4420
Query: 3625 NEQESAEPKTVEEE 3638
E + ++V+ E
Sbjct: 4421 EEPCALGAQSVKRE 4434
Score = 33.1 bits (74), Expect = 5.6
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 19/176 (10%)
Query: 1200 MPSKAYLQKQAKAV--KKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKS 1257
MP+ L+ Q + V K + + + +++ ++ +++ + SQ + R+ P ++
Sbjct: 4191 MPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ----AVRQTPPYQEP 4246
Query: 1258 SSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQ--PALVIPPQPPTTGPP 1315
++ P + + + PGP+ T P + Q P L PP +TGP
Sbjct: 4247 GTQTSPLQGLLGCQPQLG-GFPGPQ----TGPLQELGAGPRPQGPPRLPAPPGALSTGPV 4301
Query: 1316 RKEV----PKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
V P ++P EPK+ P S ++ + P P Q P +PPP
Sbjct: 4302 LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP--TLEPPP 4355
Score = 33.1 bits (74), Expect = 5.6
Identities = 17/57 (29%), Positives = 23/57 (40%), Gaps = 8/57 (14%)
Query: 1818 PLMKKIIPAPKPKGPGEPDSPTPLHPPTP--------PILSTDRSREDSPELNPPPG 1866
P++ + P P P P EP P+ L P+ P + P L PPPG
Sbjct: 4300 PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG 4356
Score = 32.3 bits (72), Expect = 9.6
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 2541 ESSPASPLQIES-TSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLM 2599
E SP SP ES TSP S P + P P ++ ++ +LP+++ L+
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Query: 2600 -LPDGPK--PQEDG 2610
LP+ P+ P+ +G
Sbjct: 727 PLPEEPQLCPRSEG 740
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 155 bits (393), Expect = 6e-37
Identities = 80/153 (52%), Positives = 102/153 (66%), Gaps = 4/153 (2%)
Query: 3818 MRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDS 3877
++F LK K+ + +S IH GLF I A EMVIEY G IR + D REK Y+
Sbjct: 1774 LKFNQLKFRKKK-LKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYED 1832
Query: 3878 KGIGC-YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYR 3936
+GIG YMFR+D ++DAT GN ARFINHSC PNCY++VI ++ QK IVI++ + I
Sbjct: 1833 EGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINV 1892
Query: 3937 GEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN 3969
EE+TYDYKFPIED K+PC CG++ CR LN
Sbjct: 1893 NEEITYDYKFPIEDV--KIPCLCGSENCRGTLN 1923
Score = 44.3 bits (103), Expect = 0.002
Identities = 75/352 (21%), Positives = 107/352 (30%), Gaps = 64/352 (18%)
Query: 1074 RAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIK 1133
+A A G K A P P P E ++ G D +G P PP+ P +
Sbjct: 386 QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARD----SGEFRRAPAPPPLPPAE 441
Query: 1134 PVTRNK--APQEPPVKKGRRSRRCGQCPGCQVPEDC-GVCTNCLDKPKFGGRN------- 1183
P+ + K P PP G+ PE C T L+ G
Sbjct: 442 PLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDS 501
Query: 1184 -----IKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV 1238
+K+Q K+ L+ S LQ + + + + +
Sbjct: 502 RIEMLLKEQRTKLLF---LREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPT 558
Query: 1239 DSSQKPTPSARED--PAPKKSSSE-----------PPP---------------------- 1263
S +P+ + ED P P S E PPP
Sbjct: 559 PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
Query: 1264 --RKPVEEKSEEGNVSA-PGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGP----PR 1316
R P EK +EG S+ E P++ +S +P +V P P P
Sbjct: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
Query: 1317 KEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPV 1368
+P P PPPP P + P P P P PPP+
Sbjct: 679 LPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
Score = 40.0 bits (92), Expect = 0.046
Identities = 113/536 (21%), Positives = 186/536 (34%), Gaps = 99/536 (18%)
Query: 2719 GVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEP 2778
G +D ES + +T + + + +E+ ++ DR E + E S K+E
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEG 1092
Query: 2779 KMDNCHSVSRVKTQGQ---DSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDN 2835
D +VS V ++ + S ++ S ESS S+ D+ + E + + +
Sbjct: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152
Query: 2836 NNSDDCGNILPSDIMD-----FVLKNTPSMQALG-ESPESSSSELLNLGEGLGLDSNREK 2889
+ + P D + P++ +LG E +E + E +
Sbjct: 1153 VAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPL 1212
Query: 2890 DMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRL 2949
+G+ E + P EP +S E L E P+ + R P P + P
Sbjct: 1213 PVGVEEPADSREPPEEP-------GLSQEGAMLLSPEPPA--KEVEARPPLSPERAPEHD 1263
Query: 2950 AVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPP- 3008
+ + + + P SP P PE DA H S PP
Sbjct: 1264 LEVEPEPPMMLPLPLQPPLPPPRPPRPPSP--PPEPE-----------TTDASHPSVPPE 1310
Query: 3009 -------------CGSVEQGHGNNQDLTRNSSTPGLQVPV----------SPTVPIQNQK 3045
CGS+ +Q +TPG + P+ SP VP
Sbjct: 1311 PLAEDHPPHTPGLCGSL----AKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS--- 1363
Query: 3046 YVPNSTDSPGPSQISNAAVQT-------TPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV 3098
P S +P PS S +T TP +P+ L+ V LP G
Sbjct: 1364 --PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV----------CPLPTGR 1411
Query: 3099 TQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLP--- 3155
+ S ++P ++ET + P+ L L P++ +Q+ P+ LLP
Sbjct: 1412 RDE---RSGPLASPVLLETGLPLPLPLPLPLPLAL---PAVLRAQARAPTPLPPLLPAPL 1465
Query: 3156 MSHHQHLHSFPAATQSSFPPNIS------NPPSGLLIG---VQPPPDPQLLVSESS 3202
S + P + S P +S PP+G +G + P PQ V S+
Sbjct: 1466 ASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPST 1521
Score = 39.7 bits (91), Expect = 0.060
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 17/126 (13%)
Query: 1242 QKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVS-APGPESKQATTPASRKSSKQVSQ 1300
+ P P E+PA S PP +P S+EG + +P P +K+ S ++ +
Sbjct: 1209 EPPLPVGVEEPA----DSREPPEEP--GLSQEGAMLLSPEPPAKEVEARPPL-SPERAPE 1261
Query: 1301 PALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPK 1360
L + P+PP P + P P P + PPPE PE + A PS+P +P
Sbjct: 1262 HDLEVEPEPPMMLPLPLQ-PPLPPPRPPRPPSPPPE--PETTD----ASHPSVP--PEPL 1312
Query: 1361 EKEKPP 1366
++ PP
Sbjct: 1313 AEDHPP 1318
Score = 39.3 bits (90), Expect = 0.079
Identities = 42/148 (28%), Positives = 54/148 (36%), Gaps = 30/148 (20%)
Query: 1241 SQKPTPSAREDPAPKKSSSEPPPRKPVE-EKSEEGNVSAPGPESKQATTPASRKSSKQVS 1299
++ PTP PAP S P RKP +S +S GP PA +++
Sbjct: 1451 ARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP---LVRPPAGAALGREL- 1506
Query: 1300 QPALVIPPQPPTTGPPRKEVPKT-----------TPSEPKKKQPPPPESGPEQSKQKKVA 1348
L++P QP T P P+T P P QPPPP P K
Sbjct: 1507 ---LLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK--- 1560
Query: 1349 PRPSIPVK----QKPKEKEKPPPVNKQE 1372
+P K Q P E P P + E
Sbjct: 1561 ----LPFKELDNQWPSEAIPPGPRGRDE 1584
Score = 37.4 bits (85), Expect = 0.30
Identities = 45/209 (21%), Positives = 71/209 (33%), Gaps = 59/209 (28%)
Query: 1207 QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKP 1266
++ V K + + +SE +S E +SS + +PS+ ED + E +
Sbjct: 1097 EETVSIVTSKAEATSSSESSESSE-------FESSSESSPSSSEDEEEVVAREEEEEEEE 1149
Query: 1267 VEEKSEEGNVSAPGPES-----------------------------KQATTPASRKSSKQ 1297
E +EE SA GPE +A P R S
Sbjct: 1150 EEMVAEESMASA-GPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS--M 1206
Query: 1298 VSQPALVI----------PPQPP----------TTGPPRKEVPKTTPSEPKKKQPPPPES 1337
+ +P L + PP+ P + PP KEV P P++ E
Sbjct: 1207 LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV 1266
Query: 1338 GPEQSKQKKVAPRPSIPVKQKPKEKEKPP 1366
PE + +P +P + P+ PP
Sbjct: 1267 EPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295
Score = 36.2 bits (82), Expect = 0.67
Identities = 37/128 (28%), Positives = 48/128 (37%), Gaps = 23/128 (17%)
Query: 1246 PSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVI 1305
P A+ PAP S+ P + PV P PE AT + S + + A
Sbjct: 383 PPAQATPAPGFKSAFSPYQTPVAH-------FPPPPEEPTATAAFGARDSGEFRR-APAP 434
Query: 1306 PPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESG-------PEQSKQKKVAPRPSIP-VKQ 1357
PP PP P KE P T P PPPP++ P + P P ++
Sbjct: 435 PPLPPAE-PLAKEKPGTPPG------PPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLES 487
Query: 1358 KPKEKEKP 1365
P EKP
Sbjct: 488 SPAGPEKP 495
Score = 35.4 bits (80), Expect = 1.1
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 6/67 (8%)
Query: 3490 PNSMGLEQNKALSSAVQASPTSPGGSP--SSPSSGQRSASPSVPGP----TKPKPKTKRF 3543
P++ GL + A S + + P +PGG P S SSG +SP VPG P P
Sbjct: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
Query: 3544 QLPLDKG 3550
LP G
Sbjct: 1378 GLPRTPG 1384
Score = 33.9 bits (76), Expect = 3.3
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 42/196 (21%)
Query: 444 ESTPNSRF-----SAPSCGSSEKSSAA-----SQHSSQMSSDSSRSSSPSVDTSTDSQAS 493
ES+ +S F S+PS E+ A + +M ++ S +S+ D D + +
Sbjct: 1114 ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEA 1173
Query: 494 ---------------EEIQ-----VLPEERSDTPEVHPPLPIS--------QSPENESND 525
EE+ V PEER + PPLP+ + PE
Sbjct: 1174 ALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLD-EPPLPVGVEEPADSREPPEEPGLS 1232
Query: 526 RRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTP---PPPLQPASSISDHT 582
+ E + + + AP+ P PP++ P PPL P +
Sbjct: 1233 QEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPS 1292
Query: 583 PWLMPPTIPLASPFLP 598
P P T + P +P
Sbjct: 1293 PPPEPETTDASHPSVP 1308
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 150 bits (380), Expect = 2e-35
Identities = 78/146 (53%), Positives = 96/146 (65%), Gaps = 3/146 (2%)
Query: 3825 KTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC-Y 3883
K K+ + RS IH GLF I A EMVIEY G IR + D REK Y +GIG Y
Sbjct: 1564 KFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSY 1623
Query: 3884 MFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYD 3943
+FR+D ++DAT GN ARFINH C PNCY++VI I+ QK IVI++ + I EE+TYD
Sbjct: 1624 LFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYD 1683
Query: 3944 YKFPIEDASNKLPCNCGAKKCRKFLN 3969
YKFP+ED NK+PC CG + CR LN
Sbjct: 1684 YKFPLED--NKIPCLCGTESCRGSLN 1707
Score = 56.2 bits (134), Expect = 6e-07
Identities = 65/234 (27%), Positives = 93/234 (39%), Gaps = 24/234 (10%)
Query: 1217 EKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKK-SSSEPPPRK-------PVE 1268
E S +S S SS + SS+ + E+ P S+ PPPR+ PVE
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVE 1093
Query: 1269 EKSEE---GNVSAPGPESKQATTPASRKSSKQVSQPALVI-PPQPPTTGPPRKEVPKTTP 1324
E G+ P PE Q +PA + S P+ + PP+PP P P P
Sbjct: 1094 VPVPERVAGSPVTPLPE--QEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERP 1151
Query: 1325 SEPKKKQPPPPESGPEQS-KQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILSTL 1383
S P PPP + S +V P P P P+ K P P +++ G + L
Sbjct: 1152 SSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAK-FPGPASRKAPRGVERTIRNL 1210
Query: 1384 SNGNSSKQKIPADGVHR-------IRVDFKEDCEAENVWEMGGLGILTSVPITP 1430
++S K + V R R E+ EAE E+ L +L + +TP
Sbjct: 1211 PLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEV-DLAVLADLALTP 1263
Score = 49.7 bits (117), Expect = 6e-05
Identities = 154/672 (22%), Positives = 231/672 (34%), Gaps = 117/672 (17%)
Query: 27 LGGAPRQRVPALLLPP---GPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASA 83
LG P Q PA LLPP GPP P PP P + G G S
Sbjct: 623 LGYPPHQ--PAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMS- 679
Query: 84 ASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSG 143
F Q+ + LR+ + + S G G
Sbjct: 680 ----------------------------FQMQTQMLTRLH-QLRQGKGLIAASAGPPGGA 710
Query: 144 EDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPRSGSDRNSAILSDPSVFSPLNKSE 203
E FL F +E P ++ ++ RG R + L P PL S
Sbjct: 711 FGEAFLPFPPPQEAAYGLPY---ALYAQGQEGRG----AYSREAYHLPMPMAAEPLPSSS 763
Query: 204 TKSGDKIKKKDSKSIEKKRGRPPTFPGV----------KIKITHGKDISELPKGN----- 248
SG++ + + E G+ G ++K +D++ N
Sbjct: 764 V-SGEEARLPPREEAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGA 822
Query: 249 -------KEDSLKKIKRTPSATFQQATKIK-KLRAGKLSPLKSKFKTGKLQIGRKGVQI- 299
KE+ K + ++ K K KL+ L L K+G G G++
Sbjct: 823 FDQWWESKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSG----GTTGIEAF 878
Query: 300 -----VRRRGRPPSTE-RIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPR 353
+R R PS + + K PS + SE ++P + TP +ED+ Q
Sbjct: 879 AFGSGLRGALRLPSFKVKRKEPSEISEASEEKRP------RPSTP--AEEDEDDPEQEKE 930
Query: 354 RIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPV 413
+P R + D K + K A +EA+Q + + +
Sbjct: 931 AGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDR 990
Query: 414 VSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMS 473
A+ + +T EDE+ D K + + S SS SS++S SS S
Sbjct: 991 EEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSS 1050
Query: 474 SDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLP---------------ISQS 518
S SS SSS S +S D + E LP EV P P ++
Sbjct: 1051 SSSSSSSSES--SSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPL 1108
Query: 519 PENESNDRRSRRYSVSERSFGSRTTKK----LSTLQSAPQQQTSSSPPPPLLTPPPPLQP 574
PE E++ R +E S S + AP+ S P PLL PPP +
Sbjct: 1109 PEQEASPARPA--GPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLL--PPPKKR 1164
Query: 575 ASSISDHTPWLMP-PTIPLASPFLPASTAPMQGKRKSILR-EPTFRWTSLKHS---RSEP 629
++S ++P P P A+P P + P RK+ E T R L H+ +S P
Sbjct: 1165 RKTVSFSAIEVVPAPEPPPATP--PQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWP 1222
Query: 630 QYFSSAKYAKEG 641
+ S ++ G
Sbjct: 1223 EEVSRGGRSRAG 1234
Score = 47.4 bits (111), Expect = 3e-04
Identities = 41/177 (23%), Positives = 64/177 (36%), Gaps = 19/177 (10%)
Query: 1207 QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDS-------SQKPTPSAREDPAPKKSSS 1259
+++A KKE + E ++S SS DS S + S+ + SSS
Sbjct: 990 REEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSS 1049
Query: 1260 EPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQ----PPTTGPP 1315
E S E P + + +P R+ P V P+ P T P
Sbjct: 1050 SSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLP 1109
Query: 1316 RKEVPKTTPSEPKKKQPP--------PPESGPEQSKQKKVAPRPSIPVKQKPKEKEK 1364
+E P+ P ++ PP PP P + + P IP+ PK++ K
Sbjct: 1110 EQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRK 1166
Score = 45.8 bits (107), Expect = 8e-04
Identities = 44/174 (25%), Positives = 65/174 (37%), Gaps = 25/174 (14%)
Query: 1202 SKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSARED------PAPK 1255
SK L + S++S S SS + SS + S+ ED PA
Sbjct: 1015 SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL 1074
Query: 1256 KSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPP 1315
S+S PP PV + V P PE + P +P Q + P
Sbjct: 1075 PSASPPPREVPVPTPAP---VEVPVPE-------------RVAGSPVTPLPEQEASPARP 1118
Query: 1316 RKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVN 1369
++ PS P + PP P +GP + + RPS P+ P K++ V+
Sbjct: 1119 AGPTEESPPSAPLR--PPEPPAGPP-APAPRPDERPSSPIPLLPPPKKRRKTVS 1169
Score = 42.4 bits (98), Expect = 0.009
Identities = 117/607 (19%), Positives = 195/607 (32%), Gaps = 110/607 (18%)
Query: 449 SRFSAPSCGSSEKSSAASQHSS-----QMSSDSSRSSSPSVDTSTDSQASEEIQVL---- 499
+R +P+ ++ +S +QHSS +M RS + + T+ + VL
Sbjct: 466 ARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARD 525
Query: 500 -----PEERSDTPEVHPPLPIS----------------QSPENESNDRRSRRYSVSERSF 538
P P PP P + +SP+ ++ S S +
Sbjct: 526 TGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEI 585
Query: 539 GSRTTKKLSTLQSAPQQQTSSSPPPPLLTPP---------PPLQPASSISDHTPWLMPPT 589
P QQ PPPP PP PP QPA + PP
Sbjct: 586 SDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPE 645
Query: 590 IPLASPFLPA------------STAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKY 637
P P P G + T T L H + + +A
Sbjct: 646 YPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRL-HQLRQGKGLIAASA 704
Query: 638 AKEGLIRKPIFDNFRPPPLTPEDVGFA---SGFSASGTAASARLFSPLHSGTRFDMHKRS 694
G F F PP + +A G G + P+ + S
Sbjct: 705 GPPGGAFGEAFLPFPPPQEAAYGLPYALYAQGQEGRGAYSREAYHLPMPMAAE-PLPSSS 763
Query: 695 PLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSS------SGVSNRKRKRKVFSPI---- 744
R P E + + E TLP+ T + + R RK+ +
Sbjct: 764 VSGEEARLPPRE-EAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGA 822
Query: 745 -------RSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVS------SSLSISVSPLAT-S 790
+ E P + + + E + L P +S S + + A S
Sbjct: 823 FDQWWESKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGS 882
Query: 791 ALNPTFTFPSHSLTQSGES----AEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT- 845
L PS + + S A + +RPR T A + PG++
Sbjct: 883 GLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPP 942
Query: 846 ----ERGRNKDKAPEELSKDRDADKSVEK---DKSRERDREREKENKRESRKEKRKKGSE 898
ERG+ + K + + D + +++ ++ +K E D E E++ RE + KK +E
Sbjct: 943 KRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETE 1002
Query: 899 IQ----------SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSV 948
+ S +LY GE+ +TS S ++ SSS S + +S
Sbjct: 1003 VSDGEDEESDSSSKCSLYADSD-------GENDSTSDSESSSSSSSSSSSSSSSSSSSSS 1055
Query: 949 TLGDTTA 955
+ ++++
Sbjct: 1056 SSSESSS 1062
Score = 41.6 bits (96), Expect = 0.016
Identities = 76/402 (18%), Positives = 149/402 (37%), Gaps = 55/402 (13%)
Query: 981 PSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKS 1040
P E E + P++ TV + + + + + K V ++ A Q + ++
Sbjct: 773 PREEAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEE 832
Query: 1041 KSLKQTDQPKAQGQESDSSETSVRGPRIKHVC--RRAAVALGRKRAVFPDDMPTLSALP- 1097
K+ + K Q +E D +T ++ P + + ++ G + F + LP
Sbjct: 833 KAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPS 892
Query: 1098 WEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQ 1157
++ + K S + SE+ P +P P ++ E + G R
Sbjct: 893 FKVKRKEPSEISE-------ASEEKRP-----RPSTPAEEDEDDPEQEKEAGEPGR---- 936
Query: 1158 CPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKE 1217
PG + P+ ++ K G++ K + S+ Q + +K E
Sbjct: 937 -PGTKPPK------RDEERGKTQGKHRKSFA-----------LDSEGEEASQESSSEKDE 978
Query: 1218 KKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSS----------EPPPRKPV 1267
+ + E+ + +E +V D+++K T + + SSS E
Sbjct: 979 EDDEEDEEDEDREEAV-----DTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDS 1033
Query: 1268 EEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEP 1327
E S + S+ S +++ +S +SS + + P P+ PP +EVP TP+
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSE-DEEEEERPAALPSASPPPREVPVPTPAPV 1092
Query: 1328 KKKQPPPPESGP--EQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
+ P P +Q+ RP+ P ++ P PP
Sbjct: 1093 EVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPP 1134
Score = 39.3 bits (90), Expect = 0.079
Identities = 22/41 (53%), Positives = 29/41 (70%)
Query: 61 AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASS 101
A++A+ S+ A A+S+ASSSS SSSSSSSSS+SS
Sbjct: 316 ASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSS 356
Score = 38.1 bits (87), Expect = 0.18
Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 12/204 (5%)
Query: 659 EDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESV-TL 717
+ + +G +A GT + +P T F ++ +FTP + + S +
Sbjct: 223 DTAAYPAGTTAVGTPGNG---TPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGST 279
Query: 718 PSNRTSAGTSSSGVSNRKRKRK------VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLT 771
P ++ SA +SS+ ++ K +R FS S S + T +++ S
Sbjct: 280 PYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSA 339
Query: 772 PPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQT--SAPAEPFSS 829
SS+SSS S S S ++ + +P++ + + + PR+ T P PF+
Sbjct: 340 SSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAE 399
Query: 830 SSPTPLFPWFTPGSQTERGRNKDK 853
++ P +T E R D+
Sbjct: 400 NTAERFPPSYTSYLPPEPSRPTDQ 423
Score = 37.0 bits (84), Expect = 0.39
Identities = 20/43 (46%), Positives = 31/43 (72%)
Query: 59 AVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASS 101
+ ++A+ A ++ A A++SA+SSS +SSSSSSSSS+SS
Sbjct: 315 SASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSS 357
Score = 37.0 bits (84), Expect = 0.39
Identities = 40/163 (24%), Positives = 60/163 (36%), Gaps = 19/163 (11%)
Query: 1216 KEKKSKTS-----EKKDSKESSVVKNVVDS-SQKPTPSAREDPAPKKSSSEPPPRKPVEE 1269
KE++SK S +++ + SS+V D+ S+ P+ S P + + P
Sbjct: 497 KEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGS 556
Query: 1270 KSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
+P + +P S ++S P P T PP++ P P P
Sbjct: 557 GEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPT-PPQQPPPPPPPPPP-- 613
Query: 1330 KQPPP-----PESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
PPP P P + PRP P P E PPP
Sbjct: 614 --PPPYLASLPLGYPPHQPAYLLPPRPDGP---PPPEYPPPPP 651
Score = 35.0 bits (79), Expect = 1.5
Identities = 18/46 (39%), Positives = 32/46 (69%)
Query: 62 AAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLR 107
+A++A+ ++ + AA +++S+SS+S SSSSSSS+SS + R
Sbjct: 315 SASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFR 360
Score = 35.0 bits (79), Expect = 1.5
Identities = 20/46 (43%), Positives = 29/46 (63%)
Query: 56 SPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASS 101
S + A+ A A ++ A A+++S +SSSS+SSSSSSS SS
Sbjct: 317 SSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSS 362
Score = 34.3 bits (77), Expect = 2.5
Identities = 23/46 (50%), Positives = 29/46 (63%), Gaps = 7/46 (15%)
Query: 59 AVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPA 104
A+AA AA SS +A++S+ SSSS+SSSSSSSS S A
Sbjct: 326 AIAATTAATASS-------SASSSSLSSSSSSSSSSSSSQFRSSDA 364
Score = 33.9 bits (76), Expect = 3.3
Identities = 33/135 (24%), Positives = 49/135 (36%), Gaps = 18/135 (13%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
S+ ++ S ++ ++++S SS +SS SS SSS S S A+ R
Sbjct: 317 SSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRY 376
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKL-----STLQSAPQQQTSS 559
+PP RR+ R F T ++ S L P + T
Sbjct: 377 QRHTSYPP-------------RRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQ 423
Query: 560 SPPPPLLTPPPPLQP 574
PP PPP P
Sbjct: 424 DYRPPASEAPPPEPP 438
Score = 33.9 bits (76), Expect = 3.3
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 14/98 (14%)
Query: 1254 PKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL-VIPPQPPTT 1312
P++++ E PP P E + E P + SR + + PA PP+PP
Sbjct: 384 PRRATREEPPGAPFAENTAE---RFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEP 440
Query: 1313 G---------PPRKEV-PKTTPSEPKKKQPPPPESGPE 1340
G P R+EV P+ P + P PE+ E
Sbjct: 441 GGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNE 478
Score = 33.5 bits (75), Expect = 4.3
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 17/76 (22%)
Query: 1252 PAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPT 1311
PAP PPP P P P A+ P QPA ++PP+P
Sbjct: 596 PAPTPPQQPPPPPPP-----------PPPPPPYLASLPLGYPPH----QPAYLLPPRP-- 638
Query: 1312 TGPPRKEVPKTTPSEP 1327
GPP E P P P
Sbjct: 639 DGPPPPEYPPPPPPPP 654
Score = 33.5 bits (75), Expect = 4.3
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 1237 VVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSK 1296
VV +++P P + ++ E + EE+ EE + S+ + + A S +S
Sbjct: 1342 VVAEAEEPKPQQLQQ---QREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHA 1398
Query: 1297 QVSQPALVIPPQPPTTGPPRKEVPKTT 1323
+ +P PP PP PR E + T
Sbjct: 1399 RRRRPPPPPPPPPPRAYEPRSEFEQMT 1425
Score = 32.7 bits (73), Expect = 7.4
Identities = 38/143 (26%), Positives = 56/143 (39%), Gaps = 6/143 (4%)
Query: 2164 SAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSS----LSPQRSKLRIMSPMRTGNTY 2219
+A P TT + T G+ S S S R T S +PQ S+ + R Y
Sbjct: 224 TAAYPAGTT-AVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTS-RGSTPY 281
Query: 2220 SRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSH 2279
S+++ S STT T+ S + S S T++++ T T + S
Sbjct: 282 SQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASS 341
Query: 2280 LDGSSSSEMKQSSASDLVSKSSS 2302
SSSS SS+S S +
Sbjct: 342 SSLSSSSSSSSSSSSSQFRSSDA 364
Score = 32.3 bits (72), Expect = 9.6
Identities = 106/469 (22%), Positives = 155/469 (33%), Gaps = 87/469 (18%)
Query: 2756 DRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTP 2815
D PE EKE G K PK D R KTQG+ L S +S+
Sbjct: 923 DDPEQ--EKEAGEPGRPGTK-PPKRDE----ERGKTQGKHRKSFALDSEGEEASQESSSE 975
Query: 2816 SDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELL 2875
D+ + D ++ +D + +D K T E +SSS L
Sbjct: 976 KDE-----------EDDEEDEEDED-----REEAVDTTKKETEVSDGEDEESDSSSKCSL 1019
Query: 2876 NLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISA---EEQFELPLELPSDLS 2932
DS + + S ++ SS SSS S+ EE+ E P LPS
Sbjct: 1020 YADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPS--- 1076
Query: 2933 VLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPD 2992
+ P R + V + E+ S V P PE +P
Sbjct: 1077 ----------ASPPPREVPVPTPAPVEVPVPERVAGSP----------VTPLPEQEASPA 1116
Query: 2993 HFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTD 3052
+ S P E G R P +P+ P P + +K V S
Sbjct: 1117 R--PAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPP-PKKRRKTVSFSAI 1173
Query: 3053 SPGPSQISNAAVQTTPPHLK---PATEKL------IVVNQNMQPLYVLQTLPNGVTQ--- 3100
P+ A TPP K PA+ K + N + ++++ P V++
Sbjct: 1174 EVVPAPEPPPA---TPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGR 1230
Query: 3101 -----KIQLTSSVSSTPSVMETNTSVLG-----PMGGGLTLTTGLNPSLPTSQSLFPSAS 3150
+ +LT + P E + +VL P GL + S T S
Sbjct: 1231 SRAGGRGRLTEEEEAEPGT-EVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERP 1289
Query: 3151 KGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVS 3199
+ LL SH H++ A + + P PP +P P P L S
Sbjct: 1290 RPLL--SHILLEHNYALAVKPTPPAPALRPP-------EPVPAPAALFS 1329
Score = 32.3 bits (72), Expect = 9.6
Identities = 43/189 (22%), Positives = 66/189 (34%), Gaps = 15/189 (7%)
Query: 2380 DQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKE 2439
D+ +DS+ + D D E + S S+ SS + SSS +S E +E
Sbjct: 1008 DEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEE 1067
Query: 2440 KHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDK------IGDKGLS 2493
+ + P E + EV PE + P + + G S
Sbjct: 1068 EERPAAL--PSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEES 1125
Query: 2494 MPGVPKAPPMQVEGSAKELQAPRKRTVK--VTLTPLKMENESQSKNALK-----ESSPAS 2546
P P PP G P +R L P K ++ S +A++ E PA+
Sbjct: 1126 PPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPAT 1185
Query: 2547 PLQIESTSP 2555
P Q + P
Sbjct: 1186 PPQAKFPGP 1194
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 100 bits (250), Expect = 2e-20
Identities = 51/129 (39%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Query: 3823 LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC 3882
+++ SK+ + + S + G G+F K + E + EY G +I + D+R K YD K +
Sbjct: 567 IQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD-KYMCS 625
Query: 3883 YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTY 3942
++F +++ VVDAT GN RF NHS PNCY++V+ ++G I IFA R I GEEL +
Sbjct: 626 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 685
Query: 3943 DYKFPIEDA 3951
DY++ DA
Sbjct: 686 DYRYSQADA 694
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 100 bits (250), Expect = 2e-20
Identities = 51/129 (39%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Query: 3823 LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC 3882
+++ SK+ + + S + G G+F K + E + EY G +I + D+R K YD K +
Sbjct: 611 IQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD-KYMCS 669
Query: 3883 YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTY 3942
++F +++ VVDAT GN RF NHS PNCY++V+ ++G I IFA R I GEEL +
Sbjct: 670 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 729
Query: 3943 DYKFPIEDA 3951
DY++ DA
Sbjct: 730 DYRYSQADA 738
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 100 bits (250), Expect = 2e-20
Identities = 49/116 (42%), Positives = 70/116 (60%), Gaps = 1/116 (0%)
Query: 3836 SPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDA 3895
S + G G F K ++ E + EY G +I + D+R K YD K + ++F +++ VVDA
Sbjct: 620 SDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD-KYMSSFLFNLNNDFVVDA 678
Query: 3896 TMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDA 3951
T GN RF NHS PNCY++V+ ++G I IFA R I GEEL +DY++ DA
Sbjct: 679 TRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADA 734
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 100 bits (248), Expect = 4e-20
Identities = 334/1599 (20%), Positives = 536/1599 (33%), Gaps = 225/1599 (14%)
Query: 2103 TESSSKESQNTAEIISPPSPDR---PPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGC 2159
T ++ ++T SP SPDR P + +SG S P + T P
Sbjct: 271 TTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSH----SRPGPTHTIAFPDS 326
Query: 2160 RPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTY 2219
+P + +H I D LS G + SSL P+ + SP T T
Sbjct: 327 TTMPGVSQESTASHSIPGSTDTTLSPGTTT-------PSSLGPESTTFH-SSPGYTKTTR 378
Query: 2220 SRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNT---STSSNLQRTVVTVGNK 2276
+N ++ +T + SS L P +S+T G+ T S S+ + G
Sbjct: 379 LPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTT 438
Query: 2277 NSHLDGSSSSEMKQSSASDL-VSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQV 2335
++ + S++ SS S SS+ G + SS + P + V
Sbjct: 439 SAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHV 498
Query: 2336 HNTTS--RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSP 2393
+T+ R ++ F E S+ S S+E+ +F G T ST +A +
Sbjct: 499 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATF-----HGSTTHTKSSTPSTTAALAHT 553
Query: 2394 DEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEK------------- 2440
+ + + + + + S+I S R K S +
Sbjct: 554 SYHSSLGSTETTHFRDSSTI-------SGRSEESKASHSSPDAMATTVLPAGSTPSVLVG 606
Query: 2441 HSSKSFLEPGQV-TTGEEGNLKPEFMDEVLTPEYMGQR-------PCNNVSSDKIGDKGL 2492
S+ S + G + TT G+ + E T Y R P + SS +
Sbjct: 607 DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTT 666
Query: 2493 S-----------MPGVPKAPPMQVEGSAKELQ-APRKRTVKVTLTPLKMENESQSKNALK 2540
S PG P + E +A P T+ T + +
Sbjct: 667 SHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSR 726
Query: 2541 ESSPASPLQIESTSPTEPISAS---ENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRN 2597
S + L ++T+ + + AS + P SP ++ + +S + + P
Sbjct: 727 PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDT 786
Query: 2598 LMLPDG-------PKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSS 2650
P P GS P ARS GL E+ Y S
Sbjct: 787 RPAPPTTTSAFVEPSTTSHGS-PSSIPTTHISARSTTS-GLV----------EESTTYHS 834
Query: 2651 STGKKRGKRSAEGQVDGA--DDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQ 2708
S G + E ++ +TS + + + S+ EE + H+
Sbjct: 835 SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 894
Query: 2709 CDLPKISQLDG-VDDGTESDTSVTATTRKSSQIPKRNGK-----ENGTENLKIDRPEDAG 2762
P S G ++ T S +S AT + +P R+ E+ T + E
Sbjct: 895 THFPDSSTTSGRSEESTASHSSQDATG--TIVLPARSTTSVLLGESTTSPISSGSMETTA 952
Query: 2763 EKEHVTKSSVGHKNEPKMDNCHS----VSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDK 2818
T + ++ + S +S T E +S HT+ D
Sbjct: 953 LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS 1012
Query: 2819 NLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSEL-LNL 2877
+ S S ++D +LP+ + PS ++ S S++ L+
Sbjct: 1013 TTTPGLSRHSTTSHSSPGSTDT--TLLPAS----TTTSGPSQESTTSHSSSGSTDTALSP 1066
Query: 2878 GEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTR 2937
G L +E F TT DS+ SS I E + S + L+
Sbjct: 1067 GSTTALSFGQESTT--FHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPA 1123
Query: 2938 SPTVPSQNPSRLAVISDSGEKRVTITEKSVASS---ESDPALLSPGVDPTPEGHMTPDHF 2994
S T P A + T + S A++ ES SPG PT HF
Sbjct: 1124 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT-------HF 1176
Query: 2995 IQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP 3054
P S GH + +S P S + S SP
Sbjct: 1177 -------------PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 1223
Query: 3055 GPSQISNAAVQTTPPHL---------KPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLT 3105
G ++I+ TT P L P + + +M L V + +Q
Sbjct: 1224 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 1283
Query: 3106 SSVS----STPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQH 3161
S+VS +TP + E +T+V G T ++FP ++ +
Sbjct: 1284 STVSPASTTTPGLSEESTTVYSSSRGS------------TETTVFPHSTTTSVHGEEPTT 1331
Query: 3162 LHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKR 3221
HS PA+T ++ S SGL P S +S +T L T+ T G +
Sbjct: 1332 FHSRPASTHTTLFTEDST-TSGLTEESTAFPG-----SPASTQTGLPATLTTADLGEEST 1385
Query: 3222 PISRLQTRKNKKLAPS-STPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR 3280
KL+P+ ST S + S ++ + + LP P+ L +T+ +
Sbjct: 1386 TFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT 1445
Query: 3281 TV----PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQD------TSHLTSGS 3330
+ + + +S E + G T TA ST + D TSH + GS
Sbjct: 1446 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS 1505
Query: 3331 VSG-LASSSSVLNVVSMQTTT-----TPTSSASVPGHVTLTNPRLLGTP---DIGSISNL 3381
L+ S+ + + Q+TT T + +P + TP GS+
Sbjct: 1506 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 1565
Query: 3382 LIKASQQSLGIQDQPVAL---PPSSGMFPQ-LGTSQTPSTAAITAASSICVLPSTQTTGI 3437
L AS S G+Q++ P SS P GT+ P + T S ST TT
Sbjct: 1566 LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR---PSSTPTTHF 1622
Query: 3438 TAASPS-GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLE 3496
+A+S + G ++E T +HSS +A P S + V P + +
Sbjct: 1623 SASSTTLGRSEE-------------STTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 1669
Query: 3497 QNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHK 3556
++A+ S T+ G S S + +SP P T T G ++
Sbjct: 1670 SGSTETTALPGSTTTAGLSEKSTTF---YSSPRSPDTTLSPAST------TSSGVSEEST 1720
Query: 3557 VSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTAS 3595
SH R S+ TT+ T PG Q+ TAS
Sbjct: 1721 TSHSRPGST-------HTTAFPGSTTMPG--VSQESTAS 1750
Score = 98.6 bits (244), Expect = 1e-19
Identities = 327/1580 (20%), Positives = 535/1580 (33%), Gaps = 227/1580 (14%)
Query: 2096 AHSPTSFTESSSKESQ----NTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYS 2151
A S TS S S+ +T P SP P S+ S + Y PR + S
Sbjct: 2958 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS-----PRSPDATLS 3012
Query: 2152 P-TQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHST-----SSLSP--- 2202
P T S G S P + D +SGL + HS+ ++LSP
Sbjct: 3013 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGST 3072
Query: 2203 ------QRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSL 2256
Q+S SP T T ++ + +T SS + L P +S+++
Sbjct: 3073 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 3132
Query: 2257 GQNTSTS-----SNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDL-VSKSSSLKGEKTKV 2310
Q ST+ S+ T G + ++ S++ + SS S SS+ G +
Sbjct: 3133 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 3192
Query: 2311 LSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHL 2370
+ SS G+ +P + V T+ ++ + A P S + +
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS------- 3245
Query: 2371 HLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGK 2430
+ + + S+ SPD + SG+S S+ + GS+ G
Sbjct: 3246 ----------EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST-HTTAFPGS 3294
Query: 2431 KSCKETFKEKHSSKSFLEPGQV-TTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGD 2489
+ +E +S S PG TT G+ + T + G + + + D
Sbjct: 3295 TTMPGVSQESTASHS--SPGSTDTTLSPGSTTASSLGPESTTFHSGP---GSTETTLLPD 3349
Query: 2490 KGLSMPGVPKAPPMQVE-GSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPL 2548
+ + + P+ GS +P T + + ES + + S +P
Sbjct: 3350 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR--------QGESTTFQSWPNSKDTTPA 3401
Query: 2549 QIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQE 2608
+TS +S + + P + P+ + ++ + + ++ V + P P
Sbjct: 3402 PPTTTSAFVELSTTSH--GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP-- 3457
Query: 2609 DGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGA 2668
AR+ ++ + Y + + F S T RG+ S
Sbjct: 3458 ------------ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES-------- 3497
Query: 2669 DDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDG-VDDGTESD 2727
+TS + + + S+ EE + H+ P S G ++ T S
Sbjct: 3498 ---TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 3554
Query: 2728 TSVTATTRKSSQIPKRNGK-----ENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDN 2782
+S AT + +P R+ E+ T + E T + K+ +
Sbjct: 3555 SSQDATG--TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 3612
Query: 2783 CHS----VSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS 2838
S +S T E +S HT+ D + S S ++
Sbjct: 3613 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 3672
Query: 2839 DDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFS 2898
D +LP+ + S S+ L+ G L +E F
Sbjct: 3673 DT--TLLPAST---TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT--FHSSP 3725
Query: 2899 QQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEK 2958
TT DS+ SS I E + S + L+ S T P A +
Sbjct: 3726 GSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 3784
Query: 2959 RVTITEKSVASS---ESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQG 3015
T + S A++ ES SPG PT HF P S G
Sbjct: 3785 HTTPSPPSTATAPVEESTTYHRSPGSTPTT-------HF-------------PASSTTSG 3824
Query: 3016 HGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHL---- 3071
H + +S P S + S SPG ++I+ TT P L
Sbjct: 3825 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS 3884
Query: 3072 -----KPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS----STPSVMETNTSVL 3122
P + + +M L V + +Q S+VS +TP + E +T+V
Sbjct: 3885 TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY 3944
Query: 3123 GPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPS 3182
G T ++FP ++ + HS PA+T ++ S S
Sbjct: 3945 SSSPGS------------TETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDST-TS 3991
Query: 3183 GLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPS-STPS 3241
GL P S +S +T L T+ T G + KL+P+ ST S
Sbjct: 3992 GLTEESTAFPG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTS 4046
Query: 3242 NIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTV----PNIIKRSKSSIMYFE 3297
+ S ++ + + LP P+ L +T+ + + + + +S E
Sbjct: 4047 GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 4106
Query: 3298 PAPLLPQSVGGTAATA----AGTSTISQD--TSHLTSGSVSG-LASSSSVLNVVSMQTTT 3350
+ G T TA TS +SQ+ TSH + GS L+ S+ + + Q+TT
Sbjct: 4107 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166
Query: 3351 -----TPTSSASVPGHVTLTNPRLLGTP---DIGSISNLLIKASQQSLGIQDQPVAL--- 3399
T + +P + TP GS+ L AS S G+Q++
Sbjct: 4167 FHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSW 4226
Query: 3400 PPSSGMFPQLGTSQTPSTAAITAASSICV---LPSTQTTGITAASPS-GEADEHYQLQHV 3455
P SS P PST A+ S ST TT +A+S + G ++E
Sbjct: 4227 PSSSDTTP-----SPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE------- 4274
Query: 3456 NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGS 3515
T +HSS +A P S + V P + + ++A+ S T+ G S
Sbjct: 4275 ------STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 4328
Query: 3516 PSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETT 3575
S + +SP P T T G ++ SH R S TT
Sbjct: 4329 EKSTTF---YSSPRSPDTTLSPAST------TSSGVSEESTTSHSRPGS-------MHTT 4372
Query: 3576 SLTSGTGTPGAEAEQQDTAS 3595
+ S T PG Q+ TAS
Sbjct: 4373 AFPSSTTMPG--VSQESTAS 4390
Score = 89.0 bits (219), Expect = 9e-17
Identities = 339/1649 (20%), Positives = 552/1649 (33%), Gaps = 287/1649 (17%)
Query: 2081 PDINSTVEHDENRTIAHSP-----TSFTESSSKESQNTAEIISPPSPDRP------PHSQ 2129
P +T +E+ T SP T F SS+ + I SPD HS
Sbjct: 1150 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 1209
Query: 2130 TSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLS-SGLR 2188
TSG S RI +P + PG P + T + LS + +
Sbjct: 1210 TSGRGE----STTSRI-SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 1264
Query: 2189 SIGSRRHSTSSLSPQRSKLRIMSPMRTGN---------TYSRNNVSSVSTT---GTATDL 2236
S+G ST+S S S +SP T YS + S+ +T T T +
Sbjct: 1265 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSV 1324
Query: 2237 ESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDL 2296
H P ++ T+L ST+S L +++ GS +S A+
Sbjct: 1325 HGEEPTTFHSR-PASTHTTLFTEDSTTSGLTE-------ESTAFPGSPASTQTGLPAT-- 1374
Query: 2297 VSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS 2356
++ L E T SS S G+ KL+P +TTS + S PS
Sbjct: 1375 -LTTADLGEESTTFPSSSGSTGT----------KLSP-ARSTTSGLVGEST------PSR 1416
Query: 2357 VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINE 2416
+S SS E + P +++ + + ++ SPD T SG+S SS +
Sbjct: 1417 LSPSSTETTTLPGSPTTPSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 1473
Query: 2417 HMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQ 2476
GS+ F + ++ + + +G+ + T +GQ
Sbjct: 1474 QPGSTH-----------TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 1522
Query: 2477 RPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKR---TVKVTLTPLK----- 2528
+ SS GD ++ P + E P ++ TLTP
Sbjct: 1523 QSTTFHSSP--GDTETTL-----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575
Query: 2529 MENESQSKNALKESSPASPLQIESTSPTEPISAS--ENPGDGPVAQPSPNNTSC-QDSQS 2585
++ ES + + SS +P +T+ +S + P P S ++T+ + +S
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635
Query: 2586 NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDI 2645
+ P + P P S + G T G+ E+
Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL---SEKST 1692
Query: 2646 PFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFRE 2705
FYSS RS + + A T S EE SH+
Sbjct: 1693 TFYSS-------PRSPDTTLSPAS-----------------TTSSGVSEESTTSHSRPGS 1728
Query: 2706 EEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKE 2765
P + + GV + + S +T D G
Sbjct: 1729 THTTAFPGSTTMPGVSQESTASHSSPGST---------------------DTTLSPGS-- 1765
Query: 2766 HVTKSSVGHKNEPKMDNCHSV--SRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDT 2823
T SS+G P+ HS S T D+ A LE+S VH+ST S L
Sbjct: 1766 -TTASSLG----PESTTFHSSPGSTETTLLPDNTTAS-GLLEASTPVHSSTGSPHTTLSP 1819
Query: 2824 YNTELLKSDSDN----NNSDDCGNILPSDIMDFVLKNT---------------PSMQALG 2864
+ + +S +S D P+ FV +T S LG
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 1879
Query: 2865 ESPESSSSELLNLGEGLGLDSNREKDMGLFE---VFSQQLPTTEPVDSSVSSSISAEEQF 2921
S ES++ + R GL E + +T+ + SS+ S +
Sbjct: 1880 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE- 1938
Query: 2922 ELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVT-ITEKSVASSESDPALLSPG 2980
E S +++ T + + S G T + S S S+ + S
Sbjct: 1939 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 1998
Query: 2981 VDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVP 3040
+ P + + +SP + G L +++TPGL +
Sbjct: 1999 SQDATGTIVLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLS---EKSTT 2051
Query: 3041 IQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQ 3100
+ P +T SP + S + ++T H +P + + T P
Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS-------TTTPGLSRH 2104
Query: 3101 KIQLTSSVSST-PSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHH 3159
SS ST +++ +T+ GP TT + T +L P ++ L
Sbjct: 2105 STTSHSSPGSTDTTLLPASTTTSGP---SQESTTSHSSPGSTDTALSPGSTTALSFGQES 2161
Query: 3160 QHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLK 3219
HS P +T ++ P+ S SG++ ++ S S RT LS +T S GL+
Sbjct: 2162 TTFHSSPGSTHTTLFPD-STTSSGIV-----EASTRVHSSTGSPRTTLSPASST-SPGLQ 2214
Query: 3220 KRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP--NHPSLLDLGSLNTS 3277
+ + PS + AP V T + +P P + P+ S TS
Sbjct: 2215 GESTAFQTHPASTHTTPSPPSTATAP---VEESTTYHRSPGSTPTTHFPA-----SSTTS 2266
Query: 3278 SHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASS 3337
H KS+I + P GT ++A ++T + S + S ++
Sbjct: 2267 GH--------SEKSTIFHSSP------DASGTTPSSAHSTTSGRGES-----TTSRISPG 2307
Query: 3338 SSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQP- 3396
S+ + + TTT S AS + + +P T + S + ++S + QP
Sbjct: 2308 STEITTLPGSTTTPGLSEASTTFYSSPRSP----TTTLSPASMTSLGVGEESTTSRSQPG 2363
Query: 3397 ---VALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASP----SGEADEH 3449
+ P+S P L T ++ ++ V P T TT + P S A H
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTH 2423
Query: 3450 YQL---------------QHVNQLLASKTGIHSSQRDLD----SASGPQVSNFTQTVDAP 3490
L +++TG+ ++ D S + P S T T +P
Sbjct: 2424 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483
Query: 3491 ---NSMGL--EQNKALSSAVQASPTSPGGSPSSPSSGQRS----ASPSVPGPTKPKPKTK 3541
+ GL E + S T+ GSP++PS ++S SP P T T
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT- 2542
Query: 3542 RFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQ 3601
G ++ SH + S+ TT+ T TPG + S S+
Sbjct: 2543 -----TSSGVSEESSTSHSQPGST-------HTTAFPDSTTTPGLSRHSTTSHSSPGST- 2589
Query: 3602 KECGQPAGQVAVLPEVQVTQNPANEQESA 3630
+LP T P+ E ++
Sbjct: 2590 --------DTTLLPASTTTSGPSQESTTS 2610
Score = 88.2 bits (217), Expect = 1e-16
Identities = 323/1593 (20%), Positives = 523/1593 (32%), Gaps = 254/1593 (15%)
Query: 2098 SPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSG----SCYYHVISKVPRIRTPSYSPT 2153
S T+ S + +++ + + +P P S TSG S YH +P + T
Sbjct: 1874 SSTTLGRSEESTTVHSSPVATATTPS-PARSTTSGLVEESTAYH--------SSPGSTQT 1924
Query: 2154 QRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPM 2213
P + T+H SS +I S +TS+L + + SP
Sbjct: 1925 MHFPESSTASGRSEESRTSH----------SSTTHTISSPPSTTSALVEEPTSYH-SSPG 1973
Query: 2214 RTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTS--LGQNTST---SSNLQR 2268
T T+ ++ ++ + +T SS ++ P S+TS LG++T++ S +++
Sbjct: 1974 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 2033
Query: 2269 TVVTVGNKNSHLDGSSSS--EMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYP 2326
T + L S++ +S A+ L S++ G + +S S GS H A+P
Sbjct: 2034 TALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 2093
Query: 2327 GIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDST 2386
+TT+ L+ S + P S + L +ST
Sbjct: 2094 D---------STTTPGLSRHSTTSHSSPGSTDTTL----------LPASTTTSGPSQEST 2134
Query: 2387 QSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSF 2446
S +S DT + + +S G S + F + +S
Sbjct: 2135 TSHSSPGSTDTALSPGSTTALS---------FGQESTTFHSSPGSTHTTLFPDSTTSSGI 2185
Query: 2447 LEPGQVTTGEEGNLKPEFMDEVLT-PEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQV 2505
+E G+ + T P G+ + P P V
Sbjct: 2186 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH----TTPSPPSTATAPV 2241
Query: 2506 EGSAKELQAPRKRTVKVTLTPLKMENESQS-KNALKESSPASPLQIESTSPTEPISASEN 2564
E S ++P + T P S K+ + SSP + T+P+ S +
Sbjct: 2242 EESTTYHRSPG--STPTTHFPASSTTSGHSEKSTIFHSSPDA----SGTTPSSAHSTTSG 2295
Query: 2565 PGDGPVAQPSPNNTSCQ-----------DSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFK 2613
G+ ++ SP +T S + + P + P G
Sbjct: 2296 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 2355
Query: 2614 RRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGK---RSAEGQVDGADD 2670
+ S + T G+ EE YSSS G R+ V G +
Sbjct: 2356 TTSRSQPGSTHSTVSPASTTTPGL---SEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412
Query: 2671 LST-SDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTS 2729
+ S + FT +SG E + Q LP + L D G ES T
Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP--ATLTTADLGEESTTF 2470
Query: 2730 VTATTRKSSQIPKRNGKENGT------ENLKIDRPEDAGEKEHVTKSSVGHKN-----EP 2778
+++ + + +G L E T S+ K+ P
Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 2530
Query: 2779 KMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS 2838
+ + ++S T E +S HT+ D + S S ++
Sbjct: 2531 RSPDA-TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2589
Query: 2839 DDCGNILPSDIMDFVLKNTPSMQAL-GESPESSSSELLNLGEGLGLDSNREKDMGLFEVF 2897
D +LP+ + PS ++ S S+ L+ G L +E F
Sbjct: 2590 DT--TLLPAS----TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT--FHSS 2641
Query: 2898 SQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGE 2957
TT DS+ SS I E + S + L+ S T P +
Sbjct: 2642 PGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAS 2700
Query: 2958 KRVTITEKSVASS---ESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHI--SSPPCGSV 3012
T + S A++ ES SPG PT H GH + I SSP
Sbjct: 2701 THTTPSPPSTATAPVEESTTYHRSPGSTPTT--HFPASSTTSGHSEKSTIFHSSPDASGT 2758
Query: 3013 EQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLK 3072
++ R ST P S + +P ST +PG S+ S T +
Sbjct: 2759 TPSSAHSTTSGRGESTTSRISPGSTEITT-----LPGSTTTPGLSEAS------TTFYSS 2807
Query: 3073 PATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS----STPSVMETNTSVLGPMGGG 3128
P + + +M L V + +Q S+VS +TP + E +T+V G
Sbjct: 2808 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGS 2867
Query: 3129 L-------TLTTGLNPSLPTSQSLFP-----------SASKGLLPMSHHQHLHSFPAATQ 3170
+ TT + PT+ P S + GL S PA+TQ
Sbjct: 2868 TETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES--TAFPGSPASTQ 2925
Query: 3171 SSFPPNIS----------------------NPPSGLLIGVQPPPDPQLLVSESSQRTDLS 3208
+ P ++ +P G+ P L S++ T L
Sbjct: 2926 TGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLP 2985
Query: 3209 TTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSN-IAPSDVVSNMTLINFTPSQLPNHPS 3267
+ TPS K + L+P++T S+ ++ S+ + + P+ +
Sbjct: 2986 GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTT 3045
Query: 3268 LLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLT 3327
L T+SH S G T AT + ST + +
Sbjct: 3046 TSGLSQEPTASH------------------------SSQGSTEATLSPGSTTASSLGQQS 3081
Query: 3328 SGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQ 3387
+ S + + L + T T+ AS P H GS+ L AS
Sbjct: 3082 TTFHSSPGDTETTL--LPDDTITSGLVEASTPTH-----------SSTGSLHTTLTPASS 3128
Query: 3388 QSLGIQDQPVAL---PPSSGMFPQ-LGTSQTPSTAAITAASSICVLPSTQTTGITAASPS 3443
S G+Q++ P SS P GT+ P + T S ST TT +A+S +
Sbjct: 3129 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR---PSSTPTTHFSASSTT 3185
Query: 3444 -GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALS 3502
G ++E T +HSS +A P S + V P + + +
Sbjct: 3186 LGRSEE-------------STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 3232
Query: 3503 SAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRT 3562
+A+ S T+ G S S + +SP P T T G ++ SH R
Sbjct: 3233 TALPGSTTTAGLSEKSTTF---YSSPRSPDTTLSPAST------TSSGVSEESTTSHSRP 3283
Query: 3563 SSSEAHIPDQETTSLTSGTGTPGAEAEQQDTAS 3595
S+ TT+ T PG Q+ TAS
Sbjct: 3284 GST-------HTTAFPGSTTMPG--VSQESTAS 3307
Score = 85.1 bits (209), Expect = 1e-15
Identities = 302/1511 (19%), Positives = 524/1511 (34%), Gaps = 195/1511 (12%)
Query: 2085 STVEHDENRTIAHSPTSFTESSSKESQNTAEIISPP-----SPDRPP------HSQTSG- 2132
ST E+ T HS S ++ T+ + P SP P S TSG
Sbjct: 767 STTRQGESTTF-HSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGL 825
Query: 2133 ---SCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRS 2189
S YH +P + T P G + T+H SS +
Sbjct: 826 VEESTTYH--------SSPGSTQTMHFPESDTTSGRGEESTTSH----------SSTTHT 867
Query: 2190 IGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGP 2249
I S +TS+L + + SP T T+ ++ ++ + +T SS ++ P
Sbjct: 868 ISSAPSTTSALVEEPTSYH-SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 926
Query: 2250 LNSSTS--LGQNTST---SSNLQRTVVTVGNKNSHLDGSSSS--EMKQSSASDLVSKSSS 2302
S+TS LG++T++ S +++ T + L S++ +S A+ L S++
Sbjct: 927 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 986
Query: 2303 LKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSK 2362
G + +S+S GS H A+P +TT+ L+ S + P S +
Sbjct: 987 SSGVSEESTTSRSRPGSTHTTAFP---------DSTTTPGLSRHSTTSHSSPGSTDTTL- 1036
Query: 2363 EALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSS 2422
L +ST S +SS DT + + +S G S
Sbjct: 1037 ---------LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALS---------FGQES 1078
Query: 2423 RDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLT-PEYMGQRPCNN 2481
+ F + +S +E G+ + T P G+
Sbjct: 1079 TTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 1138
Query: 2482 VSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQS-KNALK 2540
+ P P VE S ++P + T P S K+ +
Sbjct: 1139 THPASTH----TTPSPPSTATAPVEESTTYHRSP--GSTPTTHFPASSTTSGHSEKSTIF 1192
Query: 2541 ESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQ-----------DSQSNNYQ 2589
SSP T+P+ S + G+ ++ SP +T S +
Sbjct: 1193 HSSP----DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 1248
Query: 2590 NLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYS 2649
+ P + P G + S + T G+ EE YS
Sbjct: 1249 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL---SEESTTVYS 1305
Query: 2650 SSTGKKRG---KRSAEGQVDGADDLS-TSDEDDLYYYNFTRTVISSGGEERLASHNLFRE 2705
SS G S V G + + S + FT +SG E +
Sbjct: 1306 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 1365
Query: 2706 EEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKE 2765
Q LP + L D G ES T +++ +++ +G + P
Sbjct: 1366 STQTGLP--ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL--VGESTPSRLSPSS 1421
Query: 2766 HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYN 2825
T + G P + + + D+ + ++ S +ST S T+
Sbjct: 1422 TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-SHSQPGSTHT 1480
Query: 2826 TELLKS--DSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGL 2883
T S SD + + + + + +LG+ + S + L
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 2884 DSNREKDMGLFEVFSQQLPTTEPVDSSV--SSSISAEEQFELPLELPSDLSVLTTRSPTV 2941
D GL E + +T + +++ +SS SA Q E S TT SP
Sbjct: 1541 DDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPG 1598
Query: 2942 PSQNPSRLAVISDSGEKRVTITEKSVASS------ESDPALLSPGVDPTPEGHMTPDHFI 2995
+ P ++ S T S +S+ ES SPG T + P
Sbjct: 1599 TTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA---LFPTRSA 1655
Query: 2996 QGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPG 3055
+ + +SP + G L +++T GL + + P++T SP
Sbjct: 1656 TSVLVGEPTTSP----ISSGSTETTALPGSTTTAGLS---EKSTTFYSSPRSPDTTLSPA 1708
Query: 3056 PSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVM 3115
+ S + ++T H +P + + T+P GV+Q + T+S SS S
Sbjct: 1709 STTSSGVSEESTTSHSRPGSTHTTAFPGS-------TTMP-GVSQ--ESTASHSSPGST- 1757
Query: 3116 ETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPP 3175
T L+P T+ SL P ++ HS P +T+++ P
Sbjct: 1758 ----------------DTTLSPGSTTASSLGPESTT----------FHSSPGSTETTLLP 1791
Query: 3176 NISNPPSGLLIGVQP------PPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTR 3229
+ + SGLL P P L + S+ R STT + S P T
Sbjct: 1792 D-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1850
Query: 3230 KNKKLAPSS--TPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIK 3287
+L+ +S +PS+ + ++ T + + H S + + + + T +++
Sbjct: 1851 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 1910
Query: 3288 RSKSSIMYFEPAPLLPQSVG-GTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSM 3346
S + + +P Q++ ++TA+G S S+ + T+ ++S S++S L
Sbjct: 1911 ESTA----YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL----- 1961
Query: 3347 QTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMF 3406
PTS S PG T+ T S + +SQ + G + LP S
Sbjct: 1962 --VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG----TIVLPARSTTS 2015
Query: 3407 PQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIH 3466
LG S T S + + + + ST T G++ S + + ++ + +G+
Sbjct: 2016 VLLGES-TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGV- 2073
Query: 3467 SSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTS---PGGSPSSPSSGQ 3523
S+ S S P ++ T D+ + GL ++ S + S + P + +S S +
Sbjct: 2074 -SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 2132
Query: 3524 RSASPSVPGPT 3534
+ S S PG T
Sbjct: 2133 STTSHSSPGST 2143
Score = 80.1 bits (196), Expect = 4e-14
Identities = 350/1690 (20%), Positives = 566/1690 (33%), Gaps = 296/1690 (17%)
Query: 2098 SPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSG----SCYYHVISKVPRIRTPSYSPT 2153
S T+ S + +++ + + +P P S TSG S YH +P + T
Sbjct: 3431 SSTTLGRSEESTTVHSSPVATATTPS-PARSTTSGLVEESTTYH--------SSPGSTQT 3481
Query: 2154 QRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPM 2213
P G + T+H SS +I S +TS+L + + SP
Sbjct: 3482 MHFPESDTTSGRGEESTTSH----------SSTTHTISSAPSTTSALVEEPTSYH-SSPG 3530
Query: 2214 RTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTS--LGQNTST---SSNLQR 2268
T T+ ++ ++ + +T SS ++ P S+TS LG++T++ S +++
Sbjct: 3531 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 3590
Query: 2269 TVVTVGNKNSHLDGSSSS--EMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYP 2326
T + L S++ +S A+ L S++ G + +S S GS H A+P
Sbjct: 3591 TALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 3650
Query: 2327 ------GIPKLAPQVHNT-----------------TSRELNVSKIGSFAEPSSVSFSSKE 2363
G+ + + H++ +S+E S S + +++S S
Sbjct: 3651 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTT 3710
Query: 2364 ALSFPHLHLRGQRNDRDQHT----DST------------QSANSSPDEDTEVKTLKLSGM 2407
ALSF + HT DST S+ SP + G+
Sbjct: 3711 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 3770
Query: 2408 SNRSSIINEHMGSSSRDRRQKGKKSCK-ETFKEKHSSKSFLE----PGQVTTGEEGNLKP 2462
S+ H S+ + E H S P TT
Sbjct: 3771 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 3830
Query: 2463 EFMDEVLTPEYMGQRPCNNVSSDK-IGDKGLS-----------MPGVPKAPPMQVEGSAK 2510
F +P+ G P + S+ G+ S +PG P + E S
Sbjct: 3831 IFHS---SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS-EASTT 3886
Query: 2511 ELQAPRKRTVKVT---LTPLKMENESQSKNALKESSPASPLQIESTSP----TEPISASE 2563
+PR T ++ +T L + ES + + S+ ++ +T+P S
Sbjct: 3887 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 3946
Query: 2564 NPGDGPVAQ-PSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSAR 2622
+PG P TS + + + + P + + +P A
Sbjct: 3947 SPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 4006
Query: 2623 ARSNMFFGLTPLYGVRSYGEEDIPFYSSS--TGKKRG--KRSAEGQVD------------ 2666
++ GL GEE F SSS TG K + + G V
Sbjct: 4007 TQT----GLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSST 4062
Query: 2667 ------GADDLSTSDEDDLYYYNFTR---------TVISSG-GEERLASHNLFREEEQCD 2710
G+ + E +Y R T SSG EE SH+
Sbjct: 4063 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 4122
Query: 2711 LPKISQLDGVDD----------GTESDTSVTATTRKS--SQIPKRNGKENGTENLKIDRP 2758
P + G+ TE+ S +TT S Q + TE + P
Sbjct: 4123 FPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL--P 4180
Query: 2759 EDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDK 2818
+D V S+ H + + + + + G S SS S PS
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT 4240
Query: 2819 ----NLLDTYN---------------TELLKSDSDNNNSDDCGN----ILPSDIMDFVLK 2855
+ TY+ T L +S+ G + P+ VL
Sbjct: 4241 AVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 4300
Query: 2856 NTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSI 2915
P+ + S S+E L EK + S + P T +S +SS
Sbjct: 4301 GEPTTSPIS----SGSTETTALPGSTTTAGLSEKSTTFYS--SPRSPDTTLSPASTTSSG 4354
Query: 2916 SAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPA 2975
+EE S + S T+P + A S G T++ S +S P
Sbjct: 4355 VSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE 4414
Query: 2976 LL----SPGV--------DPTPEGHMTPDHFIQGHMDADHISSPPCGSV-EQGHGNNQDL 3022
SPG + T G + + + H + P GS QG
Sbjct: 4415 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 4474
Query: 3023 TRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPG-PSQISNAAVQTTPPHLKPATEKLIV- 3080
NS +P P +V ST S G PS + L + E V
Sbjct: 4475 WPNSKD------TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 4528
Query: 3081 ---VNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVM--ETNTSVLGPMGGGLTLTTGL 3135
V P T V + SS ST ++ E+NT+ G G TT
Sbjct: 4529 SSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTT----SGRGEESTTSH 4584
Query: 3136 NPSLPTSQSLFPSASKGLL--PMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPD 3193
+ + T S PS + L+ P S+H S P +T ++ P+ S+ SG
Sbjct: 4585 SSTTHTISSA-PSTTSALVEEPTSYH----SSPGSTATTHFPD-SSTTSGR--------S 4630
Query: 3194 PQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTR--KNKKLAPSSTPSNIAPSDVVSN 3251
+ S SSQ D + T+ P+ + T + + ++ P + +
Sbjct: 4631 EESTASHSSQ--DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688
Query: 3252 MTLINFTPSQLPN-----HPSLLDLGSLNTSSHR------TVPNIIKRSKSSIMYFEPAP 3300
T + +PS P + L +T+ H T P+ + + S ++ E +
Sbjct: 4689 STTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV--EEST 4746
Query: 3301 LLPQSVGGT-------AATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT 3353
S G T ++TA+G S S+ + T+ ++S S++S L PT
Sbjct: 4747 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL-------VEEPT 4799
Query: 3354 SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGT-- 3411
S S PG + T+ T S + +S + GI P +SG + T
Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT-TSGRIAESTTFY 4858
Query: 3412 ----------SQTPSTAAITAASSICVLPSTQT------TGITAASPSGEADEHY---QL 3452
+ T +T ++A S+I S +T++S SGE Y +
Sbjct: 4859 ISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAES 4918
Query: 3453 QHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSP 3512
H AS T SQ S P T+T +P S+ +S+ T+P
Sbjct: 4919 THTTAFPASTTTSGLSQESTTFHSKP---GSTETTLSPGSI-------TTSSFAQEFTTP 4968
Query: 3513 GGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQ 3572
P S S AS +VPG + + T + P G+ + SH T S I Q
Sbjct: 4969 HSQPGSALSTVSPASTTVPGLS--EESTTFYSSP---GSTETTAFSHSNTMS----IHSQ 5019
Query: 3573 ETTSLTSGTG 3582
++T G
Sbjct: 5020 QSTPFPDSPG 5029
Score = 79.0 bits (193), Expect = 9e-14
Identities = 330/1634 (20%), Positives = 543/1634 (33%), Gaps = 245/1634 (14%)
Query: 2091 ENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSY 2150
E T+ SPT T S S++S T SP SPD T+ S S + P
Sbjct: 1423 ETTTLPGSPT--TPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ-PGS 1477
Query: 2151 SPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIM 2210
+ T P T+H + LS G +T+S Q+S
Sbjct: 1478 THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG--------STTASSLGQQSTTFHS 1529
Query: 2211 SPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTS-----SN 2265
SP T T ++ + +T SS + L P +S+++ Q ST+ S+
Sbjct: 1530 SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS 1589
Query: 2266 LQRTVVTVGNKNSHLDGSSSSEMKQSSASDL-VSKSSSLKGEKTKVLSSKSSEGSAHNVA 2324
T G + ++ S++ + SS S SS+ G + + SS G+
Sbjct: 1590 SDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTAL 1649
Query: 2325 YPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTD 2384
+P + V T+ ++ + A P S + + + +
Sbjct: 1650 FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS-----------------EKST 1692
Query: 2385 STQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK 2444
+ S+ SPD + SG+S S+ + GS+ G + +E +S
Sbjct: 1693 TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST-HTTAFPGSTTMPGVSQESTASH 1751
Query: 2445 SF-------LEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGV 2497
S L PG T G F + E P N +S +
Sbjct: 1752 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT-LLPDNTTASGLLE--------- 1801
Query: 2498 PKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENES---QSKNALKESSPASPLQIESTS 2554
P GS +P T + + ES QS + K++ PA P T+
Sbjct: 1802 ASTPVHSSTGSPHTTLSPAGSTTR--------QGESTTFQSWPSSKDTMPAPP-----TT 1848
Query: 2555 PTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKR 2614
+ + S P + P+ + ++ + + ++ V + P P
Sbjct: 1849 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP-------- 1900
Query: 2615 RYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTS 2674
AR+ ++ + Y + + F SST R + S TS
Sbjct: 1901 ------ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR-----------TS 1943
Query: 2675 DEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDG-VDDGTESDTSVTAT 2733
+ + + S+ EE + H+ P S G ++ T S +S AT
Sbjct: 1944 HSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT 2003
Query: 2734 TRKSSQIPKRNGK-----ENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHS--- 2785
+ +P R+ E+ T + E T + K+ + S
Sbjct: 2004 G--TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 2061
Query: 2786 -VSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNI 2844
+S T E +S HT+ D + S S ++D +
Sbjct: 2062 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT--TL 2119
Query: 2845 LPSDIMDFVLKNTPSMQAL-GESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPT 2903
LP+ + PS ++ S S+ L+ G L +E F T
Sbjct: 2120 LPAS----TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT--FHSSPGSTHT 2173
Query: 2904 TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTIT 2963
T DS+ SS I E + S + L+ S T P A + T +
Sbjct: 2174 TLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 2232
Query: 2964 EKSVASS---ESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQ 3020
S A++ ES SPG PT HF P S GH
Sbjct: 2233 PPSTATAPVEESTTYHRSPGSTPTT-------HF-------------PASSTTSGHSEKS 2272
Query: 3021 DLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHL--------- 3071
+ +S P S + S SPG ++I+ TT P L
Sbjct: 2273 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 2332
Query: 3072 KPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS----STPSVMETNTSVLGPMGG 3127
P + + +M L V + +Q S+VS +TP + E +T+V G
Sbjct: 2333 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 2392
Query: 3128 GLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIG 3187
+ T + P PT ++ +G P + HS PA+T ++ S SGL
Sbjct: 2393 --STETTVFPRTPT------TSVRGEEPTT----FHSRPASTHTTLFTEDST-TSGLTEE 2439
Query: 3188 VQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPS-STPSNIAPS 3246
P S +S +T L T+ T G + L+P+ ST S +
Sbjct: 2440 STAFPG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2494
Query: 3247 DVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSV 3306
S ++ + + LP P T P++ ++S + F +P P +
Sbjct: 2495 STPSRLSPSSTETTTLPGSP--------------TTPSLSEKSTT----FYTSPRSPDAT 2536
Query: 3307 GGTAATAAGTSTISQDTSHLTSGSVSGLA-SSSSVLNVVSMQTTTTPTSSAS-----VPG 3360
A T + + TSH GS A S+ +S +TT+ +S S +P
Sbjct: 2537 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596
Query: 3361 HVTLTNPRLLGT---PDIGSISNLLIKASQQSLGIQDQPVALPPSSG-----MFPQLGTS 3412
T + P T GS L S +L + S G +FP T+
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD-STT 2655
Query: 3413 QTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDL 3472
+ A T S P T + ++ SP + + H H++
Sbjct: 2656 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTH-------PASTHTTPSPP 2708
Query: 3473 DSASGP--------QVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSS--- 3521
+A+ P + T T P S + S+ +SP + G +PSS S
Sbjct: 2709 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2768
Query: 3522 --GQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTS 3579
G+ + S PG T ++ G+ +S T+ + P TT+L+
Sbjct: 2769 GRGESTTSRISPGST---------EITTLPGSTTTPGLSEASTTFYSS--PRSPTTTLSP 2817
Query: 3580 GTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV-LPEVQVT---QNPANEQESAEPKTV 3635
+ T E+ T+ + S PA L E T +P + + + P++
Sbjct: 2818 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRST 2877
Query: 3636 E-----EEESNFSS 3644
EE + F S
Sbjct: 2878 TTSVRGEEPTTFHS 2891
Score = 78.2 bits (191), Expect = 2e-13
Identities = 345/1681 (20%), Positives = 538/1681 (32%), Gaps = 306/1681 (18%)
Query: 2081 PDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVIS 2140
PD ++T E T +HS T + +++T ++ S P +SGS
Sbjct: 3538 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP---ISSGS------- 3587
Query: 2141 KVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSL 2200
T PG P + T H S RS + S+
Sbjct: 3588 ----------METTALPGSTTTPGLSEKSTTFH-----------SSPRSPATTLSPASTT 3626
Query: 2201 SPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGT---ATDLESSAKVVDHVLGPLNSSTSLG 2257
S S+ S R G+T++ S +T G +T SS D L P +++TS
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS 3686
Query: 2258 QNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSE 2317
ST+S+ GS+ + + S + L S E T + SS
Sbjct: 3687 SQESTTSHSS-------------SGSTDTALSPGSTTAL-----SFGQEST---TFHSSP 3725
Query: 2318 GSAHNVAYP------GIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLH 2371
GS H +P GI + + +VH++T S P
Sbjct: 3726 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG---------------- 3769
Query: 2372 LRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK 2431
L+G+ H ST + S P T + + S H +SS
Sbjct: 3770 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS----TTSGH 3825
Query: 2432 SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKG 2491
S K T S P + G G+ + +S +
Sbjct: 3826 SEKSTIFHSSPDASGTTPSSAHSTTSGR---------------GESTTSRISPG--STEI 3868
Query: 2492 LSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKM----------ENESQSKNALKE 2541
++PG P + E S +PR T TL+P M + SQ +
Sbjct: 3869 TTLPGSTTTPGLS-EASTTFYSSPRSPT--TTLSPASMTSLGVGEESTTSRSQPGSTHST 3925
Query: 2542 SSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLP 2601
SPAS + + + +S P TS + + + + P +
Sbjct: 3926 VSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFT 3985
Query: 2602 DGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSS--STGKK--RG 2657
+ +P A ++ GL GEE F SS STG K
Sbjct: 3986 EDSTTSGLTEESTAFPGSPASTQT----GLPATLTTADLGEESTTFPSSSGSTGTKLSPA 4041
Query: 2658 KRSAEGQV------------------DGADDLSTSDEDDLYYYNFTR---------TVIS 2690
+ + G V G+ + E +Y R T S
Sbjct: 4042 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 4101
Query: 2691 SG-GEERLASHNLFREEEQCDLPKISQLDGVDD----------GTESDTSVTATTRKS-- 2737
SG EE SH+ P + G+ TE+ S +TT S
Sbjct: 4102 SGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLG 4161
Query: 2738 SQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSL 2797
Q + TE + P+D V S+ H + + + + + G
Sbjct: 4162 QQSTTFHSSPGDTETTLL--PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEE 4219
Query: 2798 EAQLSSLESSRRVHTSTPSDK----NLLDTY---------------NTELLKSDSDNNNS 2838
S SS S PS + TY +T L +S+
Sbjct: 4220 STTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH 4279
Query: 2839 DDCG----NILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLF 2894
G + P+ VL P+ + S S+E L EK +
Sbjct: 4280 SSPGATGTALFPTRSATSVLVGEPTTSPI----SSGSTETTALPGSTTTAGLSEKSTTFY 4335
Query: 2895 EVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISD 2954
S + P T +S +SS +EE S + S T+P + A S
Sbjct: 4336 S--SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSS 4393
Query: 2955 SGEKRVTITEKSVASS----ESDPALLSPGV--------DPTPEGHMTPDHFIQGHMDAD 3002
G T++ S +S ES SPG + T G + + +
Sbjct: 4394 PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 4453
Query: 3003 HISSPPCGS-VEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPG-PSQIS 3060
H + P GS QG NS +P P +V ST S G PS
Sbjct: 4454 HTTLSPAGSTTRQGESTTFQSWPNSK------DTTPAPPTTTSAFVELSTTSHGSPSSTP 4507
Query: 3061 NAAVQTTPPHLKPATEKLIV----VNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSV-- 3114
+ L + E V V P T V + SS ST ++
Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567
Query: 3115 METNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLL--PMSHHQHLHSFPAATQSS 3172
E+NT+ G G TT + + T S PS + L+ P S+ HS P +T ++
Sbjct: 4568 PESNTT----SGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSY----HSSPGSTATT 4618
Query: 3173 FPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTR--K 3230
P+ S+ SG + S SSQ D + T+ P+ + T
Sbjct: 4619 HFPD-SSTTSG--------RSEESTASHSSQ--DATGTIVLPARSTTSVLLGESTTSPIS 4667
Query: 3231 NKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPN-----HPSLLDLGSLNTSSH------ 3279
+ + ++ P + + T + +PS P + L +T+ H
Sbjct: 4668 SGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4727
Query: 3280 RTVPNIIKRSKSSIMYFEPAPLLPQSVGGT-------AATAAGTSTISQDTSHLTSGSVS 3332
T P+ + + S ++ E + S G T ++TA+G S S+ + T+ ++S
Sbjct: 4728 ATTPSPARSTTSGLV--EESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 4785
Query: 3333 GLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGI 3392
S++S L PTS S PG + T+ P+ + S S++S
Sbjct: 4786 SPPSTTSAL-------VEEPTSYHSSPGSIATTH-----FPESSTTSG----RSEESTAS 4829
Query: 3393 QDQP--VALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTT-GITAASPSGEADEH 3449
P + P F G +T I+ S L ST TT G++A S
Sbjct: 4830 HSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKS-------- 4881
Query: 3450 YQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASP 3509
T ++SS R D P + P S+ + ++A AS
Sbjct: 4882 -------------TILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAST 4928
Query: 3510 TSPGGSPSSPSSGQRSASPSV---PGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE 3566
T+ G S S + + S PG + F P + VS S++
Sbjct: 4929 TTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVS--PASTTV 4986
Query: 3567 AHIPDQETTSLTSGTGTPGAEAEQQDTASV-EQSSQKECGQPAGQVAVLPEVQVTQNPAN 3625
+ ++ TT +S T +T S+ Q S P VLP T +
Sbjct: 4987 PGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ 5046
Query: 3626 E 3626
E
Sbjct: 5047 E 5047
Score = 74.7 bits (182), Expect = 2e-12
Identities = 349/1678 (20%), Positives = 535/1678 (31%), Gaps = 300/1678 (17%)
Query: 2081 PDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVIS 2140
PD ++T E T +HS T + +++T ++ S P +SGS
Sbjct: 898 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP---ISSGS------- 947
Query: 2141 KVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSL 2200
T PG P + T H S RS + S+
Sbjct: 948 ----------METTALPGSTTTPGLSERSTTFH-----------SSPRSPATTLSPASTT 986
Query: 2201 SPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGT---ATDLESSAKVVDHVLGPLNSSTSLG 2257
S S+ S R G+T++ S +T G +T SS D L P +++TS
Sbjct: 987 SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 1046
Query: 2258 QNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSE 2317
ST+S+ GS+ + + S + L S E T + S+
Sbjct: 1047 SQESTTSHSS-------------SGSTDTALSPGSTTAL-----SFGQEST---TFHSNP 1085
Query: 2318 GSAHNVAYP------GIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLH 2371
GS H +P GI + + +VH++T S P
Sbjct: 1086 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG---------------- 1129
Query: 2372 LRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK 2431
L+G+ H ST + S P T + + S H +SS
Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS----TTSGH 1185
Query: 2432 SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKG 2491
S K T S P + G G+ + +S +
Sbjct: 1186 SEKSTIFHSSPDASGTTPSSAHSTTSGR---------------GESTTSRISPG--STEI 1228
Query: 2492 LSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKM----------ENESQSKNALKE 2541
++PG P + E S +PR T TL+P M + SQ +
Sbjct: 1229 TTLPGSTTTPGLS-EASTTFYSSPRSPT--TTLSPASMTSLGVGEESTTSRSQPGSTHST 1285
Query: 2542 SSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLP 2601
SPAS + + + +S P TS + + + P +
Sbjct: 1286 VSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 1345
Query: 2602 DGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSS--STGKK--RG 2657
+ +P A ++ GL GEE F SS STG K
Sbjct: 1346 EDSTTSGLTEESTAFPGSPASTQT----GLPATLTTADLGEESTTFPSSSGSTGTKLSPA 1401
Query: 2658 KRSAEGQV------------------DGADDLSTSDEDDLYYYNFTR---------TVIS 2690
+ + G V G+ + E +Y R T S
Sbjct: 1402 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461
Query: 2691 SG-GEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENG 2749
SG EE SH+ P D T SD S TT SSQ G
Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFP--------DSTTTSDLSQEPTTSHSSQ-----GSTEA 1508
Query: 2750 TENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRR 2809
T + G++ SS G + + T +EA + S+
Sbjct: 1509 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD-------DTITSGLVEASTPTHSSTGS 1561
Query: 2810 VHTS-TPSDKNLL----DTYNTELLKSDSDNNNSDDCGNILPSDIMDFV---LKNTP--- 2858
+HT+ TP+ ++ + S SD S P ++ +TP
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621
Query: 2859 ---SMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSI 2915
S LG S ES++ G L R L PTT P+ SS S+
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE-----PTTSPI-SSGSTET 1675
Query: 2916 SAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPA 2975
+A L S+ S SP P S + S SG + T S S A
Sbjct: 1676 TALPGSTTTAGL-SEKSTTFYSSPRSPDTTLSPASTTS-SGVSEESTTSHSRPGSTHTTA 1733
Query: 2976 LLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPV 3035
P T H G D SP GS + T +SS + +
Sbjct: 1734 FPGSTTMPGVSQESTASHSSPG--STDTTLSP--GSTTASSLGPESTTFHSSPGSTETTL 1789
Query: 3036 SP-----------TVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQN 3084
P + P+ + P++T SP S ++T P+++ +
Sbjct: 1790 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG--ESTTFQSWPSSKDTMPAPPT 1847
Query: 3085 MQPLYV-LQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQ 3143
+V L T +G S SSTP+ + +S +G TT + + T+
Sbjct: 1848 TTSAFVELSTTSHG---------SPSSTPTTHFSASST--TLGRSEESTTVHSSPVATAT 1896
Query: 3144 SLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ 3203
+ P+ S + HS P +TQ+ P S+ SG SE S
Sbjct: 1897 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE-SSTASGR--------------SEES- 1940
Query: 3204 RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP 3263
RT S+T T SS P S + + S+P + A + + T +
Sbjct: 1941 RTSHSSTTHTISS-----PPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 1995
Query: 3264 NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDT 3323
+H S G++ + T ++ S +S P+ S+ TA + T+ +
Sbjct: 1996 SHSSQDATGTIVLPARSTTSVLLGESTTS-------PISSGSMETTALPGSTTTPGLSEK 2048
Query: 3324 SHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHV-TLTNPRLLGTPDIGSISNLL 3382
S S A++ S + S + T+S S PG T P TP + S
Sbjct: 2049 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST-- 2106
Query: 3383 IKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASP 3442
S S G D + LP S+ G SQ +T+ + S+ L TT ++
Sbjct: 2107 --TSHSSPGSTDTTL-LPAST---TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE 2160
Query: 3443 SGEADEHYQLQHVNQLLASKTG---IHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNK 3499
S H S T + +S R S P+ + + +P G
Sbjct: 2161 STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG----- 2215
Query: 3500 ALSSAVQASPTSPGGSPSSPSSGQRSASPSV-----PGPTKPKPKTKRFQLPLDKGNGKK 3554
S+A Q P S +PS PS+ S PG T P T G+ +K
Sbjct: 2216 -ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST---PTTHFPASSTTSGHSEK 2271
Query: 3555 HKVSHLR-----TSSSEAHIP---------------DQETTSLTSGTGTPGA-------- 3586
+ H T+ S AH E T+L T TPG
Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 2331
Query: 3587 EAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSS 3644
+ + T ++ +S G + T + + + P EE + +SS
Sbjct: 2332 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 2389
Score = 72.0 bits (175), Expect = 1e-11
Identities = 303/1511 (20%), Positives = 509/1511 (33%), Gaps = 279/1511 (18%)
Query: 2081 PDINSTVEHDENRTIAHSP-----TSFTESSSKESQNTAEIISPPSPDRP------PHSQ 2129
P +T +E+ T SP T F SS+ + I SPD HS
Sbjct: 3790 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 3849
Query: 2130 TSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLS-SGLR 2188
TSG S RI +P + PG P + T + LS + +
Sbjct: 3850 TSGRGE----STTSRI-SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 3904
Query: 2189 SIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTG----TATDLESSAKVVD 2244
S+G ST+S S + G+T+S + +S +T G + T SS +
Sbjct: 3905 SLGVGEESTTSRS------------QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 3952
Query: 2245 HVLGPLNSSTSLGQNTSTS-----SNLQRTVVTVGNKNSHLDGSSS----SEMKQSSASD 2295
+ P +++TS+ + T+ ++ T+ T + S L S+ S +
Sbjct: 3953 TTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 4012
Query: 2296 LVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPS 2355
++ L E T SS S G+ KL+P +TTS + S PS
Sbjct: 4013 ATLTTADLGEESTTFPSSSGSTGT----------KLSP-ARSTTSGLVGEST------PS 4055
Query: 2356 SVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIIN 2415
+S SS E + P +++ + + ++ SPD T SG+S SS +
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSH 4112
Query: 2416 EHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMG 2475
GS+ F + ++ + + +G+ + T +G
Sbjct: 4113 SQPGSTHTT-----------AFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLG 4161
Query: 2476 QRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRT---VKVTLTPLK---- 2528
Q+ SS GD ++ P + E P + + TLTP
Sbjct: 4162 QQSTTFHSSP--GDTETTL-----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214
Query: 2529 -MENESQSKNALKESSPASPLQIESTSPTEPISAS--ENPGDGPVAQPSPNNTSC-QDSQ 2584
++ ES + + SS +P +T+ +S + P P S ++T+ + +
Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274
Query: 2585 SNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEED 2644
S + P + P P S + G T G+ E+
Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL---SEKS 4331
Query: 2645 IPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFR 2704
FYSS RS + + A T S EE SH+
Sbjct: 4332 TTFYSSP-------RSPDTTLSPAS-----------------TTSSGVSEESTTSHSRPG 4367
Query: 2705 EEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEK 2764
P + + GV + + S +T D G
Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGST---------------------DTTLSPGS- 4405
Query: 2765 EHVTKSSVGHKNEPKMDNCHSV--SRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLD 2822
T SS+G P+ HS S T D+ A LE+S VH+ST S L
Sbjct: 4406 --TTASSLG----PESTTFHSSPGSTETTLLPDNTTAS-GLLEASTPVHSSTGSPHTTLS 4458
Query: 2823 TYNTELLKSDSDN----NNSDDCGNILPSDIMDFVLKNTPSMQALGESPESS-SSELLNL 2877
+ + +S NS D P+ FV +T S + +P + S+ L
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 4518
Query: 2878 GEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTR 2937
G E+ + T P S+ S + + S +T+
Sbjct: 4519 GRS-------EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHS--------SPGSTQ 4563
Query: 2938 SPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQG 2997
+ P N + S GE+ T + + S P+ S V+ H +P
Sbjct: 4564 TMHFPESNTT-----SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 4618
Query: 2998 HMDADHISSPPCGSVEQGHGNNQDLTRN-----SSTPGLQVPVSPTVPIQNQKY----VP 3048
H +S H ++QD T ST + + S T PI + +P
Sbjct: 4619 HFPDSSTTSGRSEESTASH-SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 4677
Query: 3049 NSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSV 3108
ST +PG S+ ++T H P++ + + L + + +++V
Sbjct: 4678 GSTTTPGLSE------KSTTFHSSPSSTPTTHFSASSTTL-----------GRSEESTTV 4720
Query: 3109 SSTPSVMETNTSVLGPMGGGLTL-TTGLNPSLPTSQSL-FPSASKGLLPMSHHQHLHSFP 3166
S+P T S GL +T + S ++Q++ FP +S + HS
Sbjct: 4721 HSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST 4780
Query: 3167 AATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTT---VATPSSGLKKRPI 3223
T IS+PPS V+ P S S ++TT ++ +SG +
Sbjct: 4781 THT-------ISSPPSTTSALVEEP------TSYHSSPGSIATTHFPESSTTSGRSEEST 4827
Query: 3224 SRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVP 3283
+ + + P P++ S ++ T +P GS+ T+ T
Sbjct: 4828 ASHSSPDTNGITP--LPAHFTTSGRIAESTTFYISP------------GSMETTLASTAT 4873
Query: 3284 NIIKRSKSSIMY---------FEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGL 3334
+KS+I+Y PA + S+ G + + + T+ S + SGL
Sbjct: 4874 TPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGL 4933
Query: 3335 ASSSSVLNVV--SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGI 3392
+ S+ + S +TT +P S + T P GS + + AS G+
Sbjct: 4934 SQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPH----SQPGSALSTVSPASTTVPGL 4989
Query: 3393 QDQPVALPPSSGMFPQLGTSQTPSTAAITAASSI----------CVLPSTQTTGITAASP 3442
++ S G S + +T +I + S VLP+T TT
Sbjct: 4990 SEESTTFYSSPGSTETTAFSHS-NTMSIHSQQSTPFPDSPGFTHTVLPATLTT------- 5041
Query: 3443 SGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALS 3502
+ T HSS + P S + V P + + + +
Sbjct: 5042 -------------TDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYT 5088
Query: 3503 SAVQASPTSPG 3513
+ AS ++ G
Sbjct: 5089 TLFPASSSTSG 5099
Score = 67.4 bits (163), Expect = 3e-10
Identities = 319/1590 (20%), Positives = 524/1590 (32%), Gaps = 250/1590 (15%)
Query: 2081 PDINSTVEHDENRTIAHSP-----TSFTESSSKESQNTAEIISPPSPDRP------PHSQ 2129
P +T +E+ T SP T F SS+ + I SPD HS
Sbjct: 2233 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 2292
Query: 2130 TSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLS-SGLR 2188
TSG S RI +P + PG P + T + LS + +
Sbjct: 2293 TSGRGE----STTSRI-SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 2347
Query: 2189 SIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTG----TATDLESSAKVVD 2244
S+G ST+S S + G+T+S + +S +T G + T SS +
Sbjct: 2348 SLGVGEESTTSRS------------QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 2395
Query: 2245 HVLGPLNSSTSLG--QNTSTSSNLQRTVVTVGNKNSHLDG--SSSSEMKQSSASDLVS-- 2298
+ P +TS+ + T+ S T T+ ++S G S+ S AS
Sbjct: 2396 TTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 2455
Query: 2299 ---KSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPS 2355
++ L E T SS S G+ L+P +TTS + S PS
Sbjct: 2456 ATLTTADLGEESTTFPSSSGSTGTT----------LSP-ARSTTSGLVGEST------PS 2498
Query: 2356 SVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIIN 2415
+S SS E + P +++ + + ++ SPD T SG+S SS +
Sbjct: 2499 RLSPSSTETTTLPGSPTTPSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSH 2555
Query: 2416 EHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMG 2475
GS+ S +HS+ S PG T + T
Sbjct: 2556 SQPGST---HTTAFPDSTTTPGLSRHSTTSHSSPGSTDT--------TLLPASTTTSGPS 2604
Query: 2476 QRPCNNVSSDKIGDKGLSMPGVPKAPPMQVE--------GSAKELQAPRKRTVK--VTLT 2525
Q + SS D LS PG A E GS P T V +
Sbjct: 2605 QESTTSHSSPGSTDTALS-PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2663
Query: 2526 PLKMENESQSKNALKESSPASP-LQIESTS-PTEPISASENPGDGPVAQPSPNNTSCQDS 2583
+ + L +S SP LQ EST+ T P S P P+ +
Sbjct: 2664 TRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSP-------PSTATAPVE 2716
Query: 2584 QSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEE 2643
+S Y P P S + + F +P
Sbjct: 2717 ESTTYHRSPGSTPTTHFPASSTT-------------SGHSEKSTIFHSSP------DASG 2757
Query: 2644 DIPFYSSSTGKKRGKRSAEGQVDGADDLSTS---------DEDDLYYYNFTR---TVISS 2691
P + ST RG+ + G+ +++T E +Y+ R T +S
Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 2817
Query: 2692 G-------GEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN 2744
GEE S + P + G+ + + + S + + +++ P+
Sbjct: 2818 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRST 2877
Query: 2745 GKENGTENLKIDRPEDAGEKE---HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQL 2801
T +++ + P + H T + + + Q L A L
Sbjct: 2878 -----TTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 2932
Query: 2802 SSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQ 2861
++ + T+ PS T + + S + PS L +P+
Sbjct: 2933 TTADLGEE-STTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 2991
Query: 2862 ALGE----------SPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSV 2911
+L E SP+++ S G+ +S+ TT DS+
Sbjct: 2992 SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ------PGSTHTTAFPDSTT 3045
Query: 2912 SSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSE 2971
+S +S E + ++ + L+ S T S S G+ T+
Sbjct: 3046 TSGLSQEPTASHSSQGSTE-ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP------- 3097
Query: 2972 SDPALLSPGVDPTPEGHMTPDHFIQG--HMDADHISSPPCGSVEQGHGNNQDLTRNSSTP 3029
D + S V+ + TP H G H SS G E+ + + +TP
Sbjct: 3098 -DDTITSGLVEAS-----TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 3151
Query: 3030 G----LQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKP-ATEKLIVVNQN 3084
PV + ++ +T S + ++T H P AT + ++
Sbjct: 3152 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 3211
Query: 3085 MQPLYV----LQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLP 3140
+ V + +G T+ L S ++ ++ T P TL+ S
Sbjct: 3212 ATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 3271
Query: 3141 TSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSE 3200
S+ S S+ P S H +FP +T P +S + P L
Sbjct: 3272 VSEESTTSHSR---PGS--THTTAFPGSTTM---PGVSQESTAS--HSSPGSTDTTLSPG 3321
Query: 3201 SSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTP- 3259
S+ + L T SG P ST + + P + ++ L TP
Sbjct: 3322 STTASSLGPESTTFHSG------------------PGSTETTLLPDNTTASGLLEASTPV 3363
Query: 3260 --SQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTS 3317
S H +L GS T SK + PAP S +T + S
Sbjct: 3364 HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTT----PAPPTTTSAFVELSTTSHGS 3419
Query: 3318 TISQDTSHLTSGSVS-GLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIG 3376
S T+H ++ S + G + S+ ++ + T TTP+ + S + + +P
Sbjct: 3420 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSP--- 3476
Query: 3377 SISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTG 3436
S Q++ + +SG + TS + +T I++A S + T
Sbjct: 3477 --------GSTQTMHFPESDT----TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 3524
Query: 3437 ITAASPSGEADEHYQLQHVNQLLASK-TGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGL 3495
+ SP A H+ + + T HSSQ + P S + + + +
Sbjct: 3525 YHS-SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 3583
Query: 3496 EQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKH 3555
++A+ S T+PG S S + +SP P T T G ++
Sbjct: 3584 SSGSMETTALPGSTTTPGLSEKSTTF---HSSPRSPATTLSPAST------TSSGVSEES 3634
Query: 3556 KVSHLRTSSSEAHIPDQETTSLTSGTGTPG 3585
SH R S+ TT+ T TPG
Sbjct: 3635 TTSHSRPGST-------HTTAFPDSTTTPG 3657
Score = 67.4 bits (163), Expect = 3e-10
Identities = 340/1649 (20%), Positives = 521/1649 (31%), Gaps = 314/1649 (19%)
Query: 2125 PPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLS 2184
P S TSG V P +PS + T PG PS + T + D LS
Sbjct: 2483 PARSTTSGL----VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538
Query: 2185 SGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVD 2244
+TSS + S P T T ++ ++ + +T SS D
Sbjct: 2539 PAT--------TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 2590
Query: 2245 HVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK 2304
L P +++TS ST+S+ GS+ + + S + L S
Sbjct: 2591 TTLLPASTTTSGPSQESTTSHSS-------------PGSTDTALSPGSTTAL-----SFG 2632
Query: 2305 GEKTKVLSSKSSEGSAHNVAYP------GIPKLAPQVHNTTSRELNVSKIGSFAEPSSVS 2358
E T + SS GS H +P GI + + +VH++T S P
Sbjct: 2633 QEST---TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG--- 2686
Query: 2359 FSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHM 2418
L+G+ H ST + S P T + + S H
Sbjct: 2687 -------------LQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2733
Query: 2419 GSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRP 2478
+SS S K T S P + G G+
Sbjct: 2734 PASSTTSGH----SEKSTIFHSSPDASGTTPSSAHSTTSGR---------------GEST 2774
Query: 2479 CNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVT---LTPLKMENESQS 2535
+ +S + ++PG P + E S +PR T ++ +T L + ES +
Sbjct: 2775 TSRISPGST--EITTLPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 2831
Query: 2536 KNALKESSPASPLQIESTSP----TEPISASENPGDGPVAQ-PSPNNTSCQDSQSNNYQN 2590
+ S+ ++ +T+P S +PG P TS + + + +
Sbjct: 2832 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHS 2891
Query: 2591 LPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSS 2650
P + + +P A ++ GL GEE F SS
Sbjct: 2892 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT----GLPATLTTADLGEESTTFPSS 2947
Query: 2651 S-----------------TGKKRGKRSAEGQVD-----GADDLSTSDEDDLYYYNFTR-- 2686
S G+ R + + G+ + E +Y R
Sbjct: 2948 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 3007
Query: 2687 -------TVISSG-GEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSS 2738
T SSG EE SH+ P D T S S T SS
Sbjct: 3008 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP--------DSTTTSGLSQEPTASHSS 3059
Query: 2739 QIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE 2798
Q G T + G++ SS G + + S + +E
Sbjct: 3060 Q-----GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL-------VE 3107
Query: 2799 AQLSSLESSRRVHTS-TPSDKNLL----DTYNTELLKSDSDNNNSDDCGNILPSDIMDFV 2853
A + S+ +HT+ TP+ ++ + S SD S P ++
Sbjct: 3108 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY 3167
Query: 2854 LK---NTP------SMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTT 2904
+TP S LG S ES++ G L R L PTT
Sbjct: 3168 HSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE-----PTT 3222
Query: 2905 EPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITE 2964
P+ SS S+ +A L S+ S SP P S + S SG + T
Sbjct: 3223 SPI-SSGSTETTALPGSTTTAGL-SEKSTTFYSSPRSPDTTLSPASTTS-SGVSEESTTS 3279
Query: 2965 KSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDAD--------HISSPPCGSVEQGH 3016
S S A P T H G D P + G
Sbjct: 3280 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGP 3339
Query: 3017 GNNQD--LTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTP--PHLK 3072
G+ + L N++ GL + + P+ + P++T SP S T P+ K
Sbjct: 3340 GSTETTLLPDNTTASGL---LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSK 3396
Query: 3073 PATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLT 3132
T L T +G S SSTP+ + +S +G T
Sbjct: 3397 DTTP---APPTTTSAFVELSTTSHG---------SPSSTPTTHFSASSTT--LGRSEEST 3442
Query: 3133 TGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGL-------- 3184
T + + T+ + P+ S + HS P +TQ+ P S+ SG
Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE-SDTTSGRGEESTTSH 3501
Query: 3185 -----LIGVQPPPDPQLLVSESSQRTDLSTTVAT--PSSGLKKRPISRLQTRKNKKLAPS 3237
I P L+ +S + +T T P S R + +
Sbjct: 3502 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS---GRSEESTASHSSQD 3558
Query: 3238 STPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSS---HRTVPNIIKRSKSSIM 3294
+T + + P+ +++ L T S + + GS+ T++ T P + ++S +
Sbjct: 3559 ATGTIVLPARSTTSVLLGESTTSPISS-------GSMETTALPGSTTTPGLSEKSTT--- 3608
Query: 3295 YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTP-- 3352
F +P P + A+T + + TSH GS A S TTTP
Sbjct: 3609 -FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS---------TTTPGL 3658
Query: 3353 ----TSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQ 3408
T+S S PG T+ LL S S+ S S G D AL P S
Sbjct: 3659 SRHSTTSHSSPGS---TDTTLLPASTTTSGSSQESTTSHSSSGSTD--TALSPGSTTALS 3713
Query: 3409 LGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSS 3468
G T ++ + + ST ++GI AS T +HSS
Sbjct: 3714 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS---------------------TRVHSS 3752
Query: 3469 QRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASP 3528
+ P S S GL+ S+A Q P S +PS PS+
Sbjct: 3753 TGSPRTTLSPASS---------TSPGLQGE---STAFQTHPASTHTTPSPPSTATAPVEE 3800
Query: 3529 SV-----PGPTKPKPKTKRFQLPLDKGNGKKHKVSHLR-----TSSSEAHIP-------- 3570
S PG T P T G+ +K + H T+ S AH
Sbjct: 3801 STTYHRSPGST---PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 3857
Query: 3571 -------DQETTSLTSGTGTPGA--------EAEQQDTASVEQSSQKECGQPAGQVAVLP 3615
E T+L T TPG + + T ++ +S G
Sbjct: 3858 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 3917
Query: 3616 EVQVTQNPANEQESAEPKTVEEEESNFSS 3644
+ T + + + P EE + +SS
Sbjct: 3918 QPGSTHSTVSPASTTTPGLSEESTTVYSS 3946
Score = 66.2 bits (160), Expect = 6e-10
Identities = 198/998 (19%), Positives = 326/998 (32%), Gaps = 115/998 (11%)
Query: 55 PSPPAVAAAAAAAGSSGAGVPGGA-----AAASAASSSSASSSSSSSSSASSGPALL--R 107
PSPP AA ++ P +A+S S S++ SS ++G AL R
Sbjct: 1594 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 1653
Query: 108 VGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPS 167
++ I + A+ G + G S + F + + SP + S
Sbjct: 1654 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL-SPASTTS 1712
Query: 168 VKTSPRKPRGRPRSGSDRNSAI-----LSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKR 222
S R GS +A + S S + S S D S +
Sbjct: 1713 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 1772
Query: 223 GRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGK---LS 279
TF G+ E +L T S + +T + LS
Sbjct: 1773 PESTTFHS--------------SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 1818
Query: 280 PLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPP 339
P S + G+ + PP+T + T
Sbjct: 1819 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1878
Query: 340 LTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIE-KEAAQLQGRK 398
E+ T V SP P+ T + + + G+ + + E++ GR
Sbjct: 1879 GRSEESTTVHSSPVATATTPS-PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 1937
Query: 399 VKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGS 458
+++ + ISS PP + L P S S+P +
Sbjct: 1938 EESRTSH-----SSTTHTISS----------------PPSTTSALVEEPTSYHSSPGSTA 1976
Query: 459 SEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQS 518
+ +S S + ++ SS + A VL E + +P + +
Sbjct: 1977 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 2036
Query: 519 PENESN---DRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPP--------PLLT 567
P + + +S + S RS + + +T ++ T+S P P T
Sbjct: 2037 PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST 2096
Query: 568 PPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILRE--PTFRWTSLKHS 625
P L S+ S +P T+ LPAST ++S P T+L
Sbjct: 2097 TTPGLSRHSTTSHSSPGSTDTTL------LPASTTTSGPSQESTTSHSSPGSTDTALSPG 2150
Query: 626 RSEPQYF---SSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPL 682
+ F S+ ++ G +F P T + AS S T + SP
Sbjct: 2151 STTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTTLSPA 2206
Query: 683 HS--------GTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTS----SSG 730
S T F H S PS A + + ES T + S T+ SS
Sbjct: 2207 SSTSPGLQGESTAFQTHPAST--HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 2264
Query: 731 VSNRKRKRKVF--SPIRSEPR-SPSHSMRTRSGRLSSSELSP------LTPPSSVSSSLS 781
S K +F SP S S +HS + G ++S +SP P S+ + LS
Sbjct: 2265 TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 2324
Query: 782 ISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTP 841
+ + +S +PT T S+T G E T++ ++P S+ S TP
Sbjct: 2325 EASTTFYSSPRSPTTTLSPASMTSLGVGEES-------TTSRSQPGSTHSTVSPASTTTP 2377
Query: 842 GSQTERGRNKDKAP---EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSE 898
G E +P E R SV ++ + ++ G
Sbjct: 2378 GLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG-- 2435
Query: 899 IQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKT 958
+ S +P S + + + T+ +++T SSS +GT ++ + V
Sbjct: 2436 LTEESTAFPGSPASTQTGLPATLTTADLGEEST-TFPSSSGSTGTTLSPARSTTSGLVGE 2494
Query: 959 KILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSS 996
+ + E T L PT PSL ++ T ++P S
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 2532
Score = 65.9 bits (159), Expect = 8e-10
Identities = 199/994 (20%), Positives = 333/994 (33%), Gaps = 107/994 (10%)
Query: 55 PSPPAVAAAAAAAGSSGAGVPGGA-----AAASAASSSSASSSSSSSSSASSGPALL--R 107
PSPP AA ++ P +A+S S S++ SS ++G AL R
Sbjct: 3151 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 3210
Query: 108 VGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPS 167
++ I + A+ G + G S + F + + SP + S
Sbjct: 3211 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL-SPASTTS 3269
Query: 168 VKTSPRKPRGRPRSGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPT 227
S R GS +A ++ +++ T S D+
Sbjct: 3270 SGVSEESTTSHSRPGSTHTTAFPGSTTM-PGVSQESTASHSSPGSTDTT----------L 3318
Query: 228 FPGVKIKITHGKDISELPKG--NKEDSLKKIKRTPSATFQQATKIKKLRAGK---LSPLK 282
PG + G + + G + E +L T S + +T + LSP
Sbjct: 3319 SPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 3378
Query: 283 SKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTK 342
S + G+ + PP+T + T
Sbjct: 3379 STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 3438
Query: 343 EDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKI---EKEAAQLQGRKV 399
E+ T V SP P+ T + + + G+ + + E + +G +
Sbjct: 3439 EESTTVHSSPVATATTPS-PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 3497
Query: 400 KTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSS 459
T + I S S+ +++ P + ST + F S S
Sbjct: 3498 TTSHSSTTHTISSAPSTTSA-LVEEPTSYHSSPG-----------STATTHFPDSSTTSG 3545
Query: 460 EKSSAASQHSSQMSSDS----SRSSSPSV----DTSTDSQASEEIQVLPEERSDTPEVHP 511
+ + HSSQ ++ + +RS++ + TS S S E LP + TP
Sbjct: 3546 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT-TPG--- 3601
Query: 512 PLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPP 571
+S+ + RS ++S S S + ST + T ++ P T P
Sbjct: 3602 ---LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG- 3657
Query: 572 LQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQY 631
L S+ S +P T+ LPAST ++S + T S
Sbjct: 3658 LSRHSTTSHSSPGSTDTTL------LPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTA 3711
Query: 632 FSSAK-----YAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHS-- 684
S + ++ G +F P T + AS S T + SP S
Sbjct: 3712 LSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 3767
Query: 685 ------GTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTS----SSGVSNR 734
T F H S PS A + + ES T + S T+ SS S
Sbjct: 3768 PGLQGESTAFQTHPAST--HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 3825
Query: 735 KRKRKVF--SPIRSEPR-SPSHSMRTRSGRLSSSELSP------LTPPSSVSSSLSISVS 785
K +F SP S S +HS + G ++S +SP P S+ + LS + +
Sbjct: 3826 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 3885
Query: 786 PLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT 845
+S +PT T S+T G E T++ ++P S+ S TPG
Sbjct: 3886 TFYSSPRSPTTTLSPASMTSLGVGEES-------TTSRSQPGSTHSTVSPASTTTPGLSE 3938
Query: 846 ERGRNKDKAP---EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSS 902
E +P E R SV +++ + ++ G +
Sbjct: 3939 ESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG--LTEE 3996
Query: 903 SALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILI 962
S +P S + + + T+ +++T SSS +GT ++ + V
Sbjct: 3997 STAFPGSPASTQTGLPATLTTADLGEEST-TFPSSSGSTGTKLSPARSTTSGLVGESTPS 4055
Query: 963 KKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSS 996
+ + E T L PT PSL ++ T ++P S
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 4089
Score = 63.5 bits (153), Expect = 4e-09
Identities = 167/794 (21%), Positives = 270/794 (34%), Gaps = 103/794 (12%)
Query: 2901 LPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRV 2960
L TT SS S+ + E SD TT SP + P ++ S
Sbjct: 4202 LHTTLTPASSTSTGLQEESTTFQSWPSSSD----TTPSPPSTTAVPVEVSTTYHSRPSST 4257
Query: 2961 TITEKSVASS------ESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQ 3014
T S +S+ ES SPG T + P + + +SP +
Sbjct: 4258 PTTHFSASSTTLGRSEESTTVHSSPGATGTA---LFPTRSATSVLVGEPTTSP----ISS 4310
Query: 3015 GHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPA 3074
G L +++T GL + + P++T SP + S + ++T H +P
Sbjct: 4311 GSTETTALPGSTTTAGLS---EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367
Query: 3075 TEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVME---TNTSVLGP------M 3125
+ + T+P + SS ST + + T S LGP
Sbjct: 4368 SMHTTAFPSST-------TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 4420
Query: 3126 GGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLL 3185
G T TT L + S L S S H L + T+ + P+
Sbjct: 4421 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 4480
Query: 3186 IGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP 3245
PP V S+ ++ T + R + +P +T + +P
Sbjct: 4481 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 4540
Query: 3246 -----SDVVSNMTLINFTPSQ-----LPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMY 3295
S +V T + +P P + G +T+SH + + I + S+
Sbjct: 4541 ARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSA 4600
Query: 3296 FEPAPLLPQSVGGTAATA--AGTSTISQDTSHLTSGSVSGLASSSSVL------NVVSMQ 3347
P S G+ AT +ST S + T+ S A+ + VL +V+ +
Sbjct: 4601 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 4660
Query: 3348 TTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFP 3407
+TT+P SS S+ T P TP + S++S P + P + F
Sbjct: 4661 STTSPISSGSME---TTALPGSTTTPGL----------SEKSTTFHSSPSSTPTTH--FS 4705
Query: 3408 QLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHS 3467
T+ S + T SS +T TT A S + E H S G
Sbjct: 4706 ASSTTLGRSEESTTVHSSPV---ATATTPSPARSTTSGLVEESTAYH------SSPGSTQ 4756
Query: 3468 SQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSAS 3527
+ +S++ S ++T + + + + +SA+ PTS SP S ++ S
Sbjct: 4757 TMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPES 4816
Query: 3528 PSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAH------IPDQETTSLTSGT 3581
+ G + + T P NG +H TS A P T+L S
Sbjct: 4817 STTSG--RSEESTASHSSP--DTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTA 4872
Query: 3582 GTPGAEAE-----------QQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESA 3630
TPG A+ Q + +S G+P + T PA+ S
Sbjct: 4873 TTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932
Query: 3631 EPKTVEEEESNFSS 3644
+ +E + F S
Sbjct: 4933 ----LSQESTTFHS 4942
Score = 62.0 bits (149), Expect = 1e-08
Identities = 139/615 (22%), Positives = 222/615 (36%), Gaps = 91/615 (14%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSS------DSSRSSSPSVDTSTDSQASEEI-- 496
ST ++ SAPS S+ S HSS S+ DSS +S S + ST S +S++
Sbjct: 863 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS-EESTASHSSQDATG 921
Query: 497 ----------QVLPEERSDTPEVHPPLPISQSPENESN---DRRSRRYSVSERSFGSRTT 543
VL E + +P + + P + + RS + S RS + +
Sbjct: 922 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 981
Query: 544 KKLSTLQSAPQQQTSSSPPP--------PLLTPPPPLQPASSISDHTPWLMPPTIPLASP 595
+T ++ T+S P P T P L S+ S +P T+
Sbjct: 982 PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL----- 1036
Query: 596 FLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAK-----YAKEGLIRKPIFDN 650
LPAST ++S + T S S + ++ G +F
Sbjct: 1037 -LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF-- 1093
Query: 651 FRPPPLTPEDVGFASGFSASGTAASARLFSPLHS--------GTRFDMHKRSPLLRAPRF 702
P T + AS S T + SP S T F H S
Sbjct: 1094 --PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST--HTTPS 1149
Query: 703 TPSEAHSRIFESVTLPSNRTSAGTS----SSGVSNRKRKRKVF--SPIRSEPR-SPSHSM 755
PS A + + ES T + S T+ SS S K +F SP S S +HS
Sbjct: 1150 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 1209
Query: 756 RTRSGRLSSSELSP------LTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGES 809
+ G ++S +SP P S+ + LS + + +S +PT T S+T G
Sbjct: 1210 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 1269
Query: 810 AEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVE 869
E T++ ++P S+ S +P S T G +++ S R + ++
Sbjct: 1270 EES-------TTSRSQPGSTHSTV------SPASTTTPGLSEESTTV-YSSSRGSTETTV 1315
Query: 870 KDKSRERDREREKENKRESRKEKR--------KKGSEIQSSSALYPVGRVSKEKVVGEDV 921
S E+ SR S + S +P S + + +
Sbjct: 1316 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 1375
Query: 922 ATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAP 981
T+ +++T SSS +GT ++ + V + + E T L PT P
Sbjct: 1376 TTADLGEEST-TFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 1434
Query: 982 SLEKEKTLCLSTPSS 996
SL ++ T ++P S
Sbjct: 1435 SLSEKSTTFYTSPRS 1449
Score = 60.5 bits (145), Expect = 3e-08
Identities = 119/557 (21%), Positives = 198/557 (35%), Gaps = 64/557 (11%)
Query: 468 HSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRR 527
HSS S ++ + + S T + S Q P TP P + P S
Sbjct: 4196 HSSTGSLHTTLTPASSTSTGLQEE-STTFQSWPSSSDTTPS---PPSTTAVPVEVSTTYH 4251
Query: 528 SRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMP 587
SR S F + +T TL + + T S P T P + A+S+ P
Sbjct: 4252 SRPSSTPTTHFSASST----TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP---- 4303
Query: 588 PTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPI 647
T P++S + P + + T ++S RS S A G+ +
Sbjct: 4304 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS---PRSPDTTLSPASTTSSGVSEEST 4360
Query: 648 FDNFRPPPLTPEDVGFASGFSASGTA--ASARLFSPLHSGTRFDMHKRSPLLRAPRFTPS 705
+ RP + F S + G + ++A SP + T + P T
Sbjct: 4361 TSHSRPGSM--HTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF 4418
Query: 706 EAHSRIFESVTLPSNRTSAGTSSSGV---SNRKRKRKVFSPIRSEPRSPSHSMRTRSGRL 762
+ E+ LP N T++G + S+ SP S R + T
Sbjct: 4419 HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST--TFQSWP 4476
Query: 763 SSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLT--QSGESAEKNQRPRKQT 820
+S + +P PP++ S+ + +S + + + PT F + S T +S ES + P
Sbjct: 4477 NSKDTTP-APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 4535
Query: 821 SAPAEPFSS------------SSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSV 868
+ P+ S+ SSP P S T GR ++ S +
Sbjct: 4536 TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAP 4595
Query: 869 EKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAK 928
+ E GS +++ +P + + E+ S S++
Sbjct: 4596 STTSALVE----------EPTSYHSSPGS---TATTHFPDSSTTSGR--SEESTASHSSQ 4640
Query: 929 KATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKT 988
ATG + + TSV LG++T G++E T L T P L ++ T
Sbjct: 4641 DATGTIVLPARST----TSVLLGESTTSPIS------SGSMETTALPGSTTTPGLSEKST 4690
Query: 989 LCLSTPSSSTVKHSTSS 1005
S+PSS+ H ++S
Sbjct: 4691 TFHSSPSSTPTTHFSAS 4707
Score = 58.9 bits (141), Expect = 1e-07
Identities = 127/583 (21%), Positives = 209/583 (35%), Gaps = 63/583 (10%)
Query: 455 SCGSSEKSSAASQHSSQMSSDSSR--SSSPSVDTSTDSQASEEIQVLPEERSD--TPEVH 510
S S++ A+ ++ + +S+ SSS S T+ S ++ E +P
Sbjct: 2446 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2505
Query: 511 PPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPP------- 563
+ SP S +S + S RS + + +T ++ ++S P
Sbjct: 2506 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 2565
Query: 564 -PLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILRE--PTFRWT 620
P T P L S+ S +P T+ LPAST ++S P T
Sbjct: 2566 FPDSTTTPGLSRHSTTSHSSPGSTDTTL------LPASTTTSGPSQESTTSHSSPGSTDT 2619
Query: 621 SLKHSRSEPQYF---SSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASAR 677
+L + F S+ ++ G +F P T + AS S T +
Sbjct: 2620 ALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRT 2675
Query: 678 LFSPLHS--------GTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTS-- 727
SP S T F H S PS A + + ES T + S T+
Sbjct: 2676 TLSPASSTSPGLQGESTTFQTHPAST--HTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2733
Query: 728 --SSGVSNRKRKRKVF--SPIRSEPR-SPSHSMRTRSGRLSSSELSP------LTPPSSV 776
SS S K +F SP S S +HS + G ++S +SP P S+
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 2793
Query: 777 SSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLF 836
+ LS + + +S +PT T S+T G E T++ ++P S+ S
Sbjct: 2794 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES-------TTSRSQPGSTHSTVSPA 2846
Query: 837 PWFTPGSQTERGRNKDKAP---EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKR 893
TPG E +P E R SV ++ + ++
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST 2906
Query: 894 KKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDT 953
G + S +P S + + + T+ +++T SSS +GT ++ +
Sbjct: 2907 TSG--LTEESTAFPGSPASTQTGLPATLTTADLGEEST-TFPSSSGSTGTTLSPARSTTS 2963
Query: 954 TAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSS 996
V + + E T L PT PSL ++ T ++P S
Sbjct: 2964 GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006
Score = 56.6 bits (135), Expect = 5e-07
Identities = 131/601 (21%), Positives = 210/601 (34%), Gaps = 104/601 (17%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + FSA S + HSS +++ +++P S S EE
Sbjct: 454 STPTTHFSASSTTLGHSEESTPVHSSPVAT----ATTPPPARSATSGHVEESTAYHRSPG 509
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
T +H P + S +E S GS T K ST + +S
Sbjct: 510 STQTMHFPESSTTSGHSEE----------SATFHGSTTHTKSSTPSTTAALAHTSYHSSL 559
Query: 565 LLTPPPPLQPASSIS---DHTPWLMPPTIPLASPFLPASTAP---MQGKRKSILREPTFR 618
T + +S+IS + + +A+ LPA + P + S + +
Sbjct: 560 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 619
Query: 619 WTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARL 678
T+L S ++P GL K F P +P+ + ++SG + +
Sbjct: 620 TTALPGSTTKP-----------GLSEKST--TFYSSPRSPDTTHLPASMTSSGVSEESTT 666
Query: 679 FSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFE-SVTLP--SNRTSAGTSSSGVSNRK 735
H R P H+ F S T+P S ++A SS G ++
Sbjct: 667 -----------SHSR----------PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDT- 704
Query: 736 RKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPT 795
SP + S T R S+E + L P ++ +S L + P+ +S +P
Sbjct: 705 ----TLSPGSTTASSLGPEYTTFHSRPGSTETT-LLPDNTTASGLLEASMPVHSSTRSPH 759
Query: 796 FTF-PSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKA 854
T P+ S T+ GES + P + + PA P ++S+ F S T G
Sbjct: 760 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA-------FVEPSTTSHGSPSSIP 812
Query: 855 PEELSKDRDADKSVEKDKS---------------RERDREREKENKRESRKEKRKKGSEI 899
+S VE+ + + R +E+ S
Sbjct: 813 TTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 872
Query: 900 QSSSAL------YPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDI------TS 947
++SAL Y S D +T+S + + SS +GT + TS
Sbjct: 873 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 932
Query: 948 VTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIG 1007
V LG++T G++E T L T P L + T S+P S S +S
Sbjct: 933 VLLGESTTSPIS------SGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 986
Query: 1008 S 1008
S
Sbjct: 987 S 987
Score = 54.3 bits (129), Expect = 2e-06
Identities = 113/547 (20%), Positives = 187/547 (34%), Gaps = 44/547 (8%)
Query: 473 SSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYS 532
SS S ++ + +ST + EE S + P + +P S SR S
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616
Query: 533 VSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPL 592
F + +T TL + + T S P T P + A+S+ P T P+
Sbjct: 1617 TPTTHFSASST----TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP----TTSPI 1668
Query: 593 ASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFR 652
+S + P + + T ++S RS S A G+ + + R
Sbjct: 1669 SSGSTETTALPGSTTTAGLSEKSTTFYSS---PRSPDTTLSPASTTSSGVSEESTTSHSR 1725
Query: 653 PPPLTPEDVGFASGFSASGTA--ASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSR 710
P + F + G + ++A SP + T + P T +
Sbjct: 1726 PG--STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1783
Query: 711 IFESVTLPSNRTSAGTSSSGV---SNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSEL 767
E+ LP N T++G + S+ SP S R + T SS +
Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST--TFQSWPSSKDT 1841
Query: 768 SPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPF 827
P PP++ S+ + +S + + + PT F + S T R + T+ + P
Sbjct: 1842 MP-APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG--------RSEESTTVHSSPV 1892
Query: 828 SSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRE 887
++++ TP T E +P + S +S E
Sbjct: 1893 ATAT-TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI 1951
Query: 888 SRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDI-- 945
S S + Y S D +T+S + + SS +GT +
Sbjct: 1952 SSPPSTT--SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009
Query: 946 ----TSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKH 1001
TSV LG++T G++E T L T P L ++ T S+P S
Sbjct: 2010 ARSTTSVLLGESTTSPIS------SGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTL 2063
Query: 1002 STSSIGS 1008
S +S S
Sbjct: 2064 SPASTTS 2070
Score = 54.3 bits (129), Expect = 2e-06
Identities = 131/603 (21%), Positives = 204/603 (33%), Gaps = 70/603 (11%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + F A S S + HSS +S ++ SS+ S + + I E +
Sbjct: 2253 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2312
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
P +S++ + RS ++S S S + ST + T S+ P
Sbjct: 2313 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372
Query: 565 LLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILR-EPTFRWTSLK 623
T P + ++++ +P T+ F T ++G+ + P T+L
Sbjct: 2373 STTTPGLSEESTTVYSSSPGSTETTV-----FPRTPTTSVRGEEPTTFHSRPASTHTTLF 2427
Query: 624 HSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLH 683
S + A G P LT D+G S S + ++ SP
Sbjct: 2428 TEDSTTSGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPAR 2485
Query: 684 SGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRK---V 740
S T + + +P R +PS E+ TLP + T+ S + R
Sbjct: 2486 STTSGLVGESTP----SRLSPSST-----ETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 2536
Query: 741 FSPIR------SEPRSPSHSM--RTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSAL 792
SP SE S SHS T + S +P S +S S +
Sbjct: 2537 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596
Query: 793 NPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS------SSP----TPLFPWFTPG 842
+ T + PS T S S S A F SSP T LFP T
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2656
Query: 843 S----QTERGRNKDKAPE-ELSKDRDADKSVEKDKSRERDREREKENK-----------R 886
S + R + +P LS ++ + + +
Sbjct: 2657 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVE 2716
Query: 887 ESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDIT 946
ES R GS + + +P + E S+ A+G SS+H
Sbjct: 2717 ESTTYHRSPGS---TPTTHFPASSTTSGH--SEKSTIFHSSPDASGTTPSSAH------- 2764
Query: 947 SVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSI 1006
S T G + ++I G+ E T L T P L + T S+P S T S +S+
Sbjct: 2765 STTSGRGESTTSRI----SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 2820
Query: 1007 GSM 1009
S+
Sbjct: 2821 TSL 2823
Score = 52.8 bits (125), Expect = 7e-06
Identities = 115/555 (20%), Positives = 194/555 (34%), Gaps = 60/555 (10%)
Query: 473 SSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYS 532
SS S ++ + +ST + EE S + P + +P S SR S
Sbjct: 3114 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 3173
Query: 533 VSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPL 592
F + +T TL + + T S P T P + A+S+ P T P+
Sbjct: 3174 TPTTHFSASST----TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP----TTSPI 3225
Query: 593 ASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFR 652
+S + P + + T ++S RS S A G+ + + R
Sbjct: 3226 SSGSTETTALPGSTTTAGLSEKSTTFYSS---PRSPDTTLSPASTTSSGVSEESTTSHSR 3282
Query: 653 PPPLTPEDVGFASGFSASGTA--ASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSR 710
P + F + G + ++A SP + T + P T +
Sbjct: 3283 PG--STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340
Query: 711 IFESVTLPSNRTSAGTSSSGV---SNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSEL 767
E+ LP N T++G + S+ SP S R + T +S +
Sbjct: 3341 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST--TFQSWPNSKDT 3398
Query: 768 SPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLT--QSGESAEKNQRPRKQTSAPAE 825
+P PP++ S+ + +S + + + PT F + S T +S ES + P + P+
Sbjct: 3399 TP-APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 3457
Query: 826 PFSS------------SSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKS 873
S+ SSP P S T GR ++ S + +
Sbjct: 3458 ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA 3517
Query: 874 RERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGR 933
E GS +++ +P + + E+ S S++ ATG
Sbjct: 3518 LVE----------EPTSYHSSPGS---TATTHFPDSSTTSGR--SEESTASHSSQDATGT 3562
Query: 934 KKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLST 993
+ + TSV LG++T G++E T L T P L ++ T S+
Sbjct: 3563 IVLPARST----TSVLLGESTTSPIS------SGSMETTALPGSTTTPGLSEKSTTFHSS 3612
Query: 994 PSSSTVKHSTSSIGS 1008
P S S +S S
Sbjct: 3613 PRSPATTLSPASTTS 3627
Score = 52.4 bits (124), Expect = 9e-06
Identities = 130/592 (21%), Positives = 208/592 (35%), Gaps = 77/592 (13%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + F A S S + HSS +S ++ SS+ S + + I E +
Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2786
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
P +S++ + RS ++S S S + ST + T S+ P
Sbjct: 2787 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846
Query: 565 LLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILR-EPTFRWTSLK 623
T P + ++++ +P T+ F ++T ++G+ + P T+L
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTV-----FPRSTTTSVRGEEPTTFHSRPASTHTTLF 2901
Query: 624 HSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLH 683
S + A G P LT D+G S S + ++ SP
Sbjct: 2902 TEDSTTSGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPAR 2959
Query: 684 SGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSP 743
S T + + +P R +PS E+ TLP + T+ S ++ ++
Sbjct: 2960 STTSGLVGESTP----SRLSPSST-----ETTTLPGSPTTPSLS-------EKSTTFYTS 3003
Query: 744 IRSEPRSPSHSMRTRSGRLSSSELSPLTP--------PSSVSSSLSISVSPLAT------ 789
RS + S + T SG S S P P S ++S +S P A+
Sbjct: 3004 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS-GLSQEPTASHSSQGS 3062
Query: 790 --SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS-----SSPT-----PLFP 837
+ L+P T S SL Q + + + T P + +S S+PT L
Sbjct: 3063 TEATLSPGSTTAS-SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 3121
Query: 838 WFTPGSQTERGRNKDKAP-EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKG 896
TP S T G ++ + D S + E SR
Sbjct: 3122 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTA----APVEVSTTYHSRPSSTPTT 3177
Query: 897 SEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAV 956
SS+ L GR E+ T S+ ATG + + TSV +G+ T
Sbjct: 3178 HFSASSTTL---GR-------SEESTTVHSSPGATGTALFPTRSA----TSVLVGEPTTS 3223
Query: 957 KTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
G+ E T L T L ++ T S+P S S +S S
Sbjct: 3224 PI------SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS 3269
Score = 51.6 bits (122), Expect = 2e-05
Identities = 137/627 (21%), Positives = 219/627 (34%), Gaps = 84/627 (13%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + F A S S + HSS +S ++ SS+ S + + I E +
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 3869
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
P +S++ + RS ++S S S + ST + T S+ P
Sbjct: 3870 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929
Query: 565 LLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKH 624
T P + ++++ +P T+ S +T+ + + + P T+L
Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRS----TTTSVRREEPTTFHSRPASTHTTLFT 3985
Query: 625 SRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHS 684
S + A G P LT D+G S S + ++ SP S
Sbjct: 3986 EDSTTSGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 4043
Query: 685 GTRFDMHKRSPLLRAPRFTP-------------SEAHSRIFESVTLPSNRTS-AGTSSSG 730
T + + +P +P T SE + + S P S A T+SSG
Sbjct: 4044 TTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSG 4103
Query: 731 VSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATS 790
VS S S+P S + S S P T SS S ++SP +T+
Sbjct: 4104 VSEES------STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS-QGSTEATLSPGSTT 4156
Query: 791 ALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS-----SSPT-----PLFPWFT 840
A SL Q + + + T P + +S S+PT L T
Sbjct: 4157 A---------SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 4207
Query: 841 PGSQTERG------------RNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRES 888
P S T G + D P S + SR + +
Sbjct: 4208 PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASST 4267
Query: 889 RKEKRKKGSEIQSS-----SALYPVGRVSKEKVVGEDVAT--SSSAKKATGRKKSS---- 937
+ ++ + + SS +AL+P R + +VGE + SS + + T S+
Sbjct: 4268 TLGRSEESTTVHSSPGATGTALFPT-RSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 4326
Query: 938 -SHDSGTDITSVTLGDTT---------AVKTKILIKKGR-GNLEKTNLDLGPTAPSLEKE 986
S S T +S DTT V + R G++ T T P + +E
Sbjct: 4327 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQE 4386
Query: 987 KTLCLSTPSSSTVKHSTSSIGSMLAQA 1013
T S+P S+ +T S GS A +
Sbjct: 4387 STASHSSPGST---DTTLSPGSTTASS 4410
Score = 49.3 bits (116), Expect = 8e-05
Identities = 161/750 (21%), Positives = 261/750 (34%), Gaps = 133/750 (17%)
Query: 2935 TTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALL-----SPGVDPTPEGHM 2989
TT S + + P V S +G T++ S + E +P S P P G
Sbjct: 383 TTTSGLLEASTP----VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG-- 436
Query: 2990 TPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPN 3049
T F++ + + SSP SSTP S T + +
Sbjct: 437 TTSAFVK--LSTTYHSSP------------------SSTPTTHFSASSTT-------LGH 469
Query: 3050 STDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS 3109
S +S P S A TTPP + AT + +++ P G TQ + S +
Sbjct: 470 SEEST-PVHSSPVATATTPPPARSAT------SGHVEESTAYHRSP-GSTQTMHFPESST 521
Query: 3110 STPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAAT 3169
++ E+ T G T T PS T+ +L ++ L + H +
Sbjct: 522 TSGHSEESAT-----FHGSTTHTKSSTPS--TTAALAHTSYHSSLGSTETTHFRDSSTIS 574
Query: 3170 QSSFPPNISNP-PSGLLIGVQPPPD-PQLLVSESSQRTDLS---TTVATPSSGLKKRPIS 3224
S S+ P + V P P +LV +S+ S T A P S K
Sbjct: 575 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 634
Query: 3225 RLQTRKNKKLAPSST--PSNIAPSDVVSNMTLINFTPSQ-----LPNHPSLLDLGSLNTS 3277
+ T + +P +T P+++ S V T + P P ++ L +T+
Sbjct: 635 KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 694
Query: 3278 SHRTV--------PNIIKRSKSSIMY--FEPAP------LLPQSVGGTAATAAG----TS 3317
SH + P S Y F P LLP + + A +S
Sbjct: 695 SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSS 754
Query: 3318 TISQDTSHLTSGSVSGLASSSSVLNVVSMQTT--TTPTSSASVPGHVTLTNPRLLGTPDI 3375
T S T+ +GS + S++ + S + T PT++++ T ++ G+P
Sbjct: 755 TRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH----GSPS- 809
Query: 3376 GSISNLLIKASQQSLGIQDQPVALPPSSGM-----FPQLGTSQTPSTAAITAASS----I 3426
SI I A + G+ ++ S G FP+ T+ + T+ SS I
Sbjct: 810 -SIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 868
Query: 3427 CVLPSTQTTGITA-----ASPSGEADEHYQLQHVNQLLASK-TGIHSSQRDLDSASGPQV 3480
PST + + +SP A H+ + + T HSSQ + P
Sbjct: 869 SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 928
Query: 3481 SNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKT 3540
S + + + + ++A+ S T+PG S S + +SP P T T
Sbjct: 929 STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF---HSSPRSPATTLSPAST 985
Query: 3541 KRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS 3600
G ++ S R S+ TT+ T TPG + S S+
Sbjct: 986 ------TSSGVSEESTTSRSRPGST-------HTTAFPDSTTTPGLSRHSTTSHSSPGST 1032
Query: 3601 QKECGQPAGQVAVLPEVQVTQNPANEQESA 3630
+LP T P+ E ++
Sbjct: 1033 ---------DTTLLPASTTTSGPSQESTTS 1053
Score = 49.3 bits (116), Expect = 8e-05
Identities = 126/572 (22%), Positives = 203/572 (35%), Gaps = 55/572 (9%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASE-EIQVLPEER 503
S+P S +A S GS+ S + ++ SS S ++ D++T S E +V
Sbjct: 2612 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671
Query: 504 SDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPP 563
S + P S + ES ++ S + TT + +AP +++++
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPAS-------THTTPSPPSTATAPVEESTTYHRS 2724
Query: 564 PLLTPPPPLQPASSISDH----TPWLMPPTIPLASPFLPASTAPMQGKRKSILREP-TFR 618
P TP +S+ S H T + P +P ST +G+ + P +
Sbjct: 2725 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 2784
Query: 619 WTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARL 678
T+L S + P S A R P P +T VG S S S ++
Sbjct: 2785 ITTLPGSTTTPG-LSEASTTFYSSPRSPT-TTLSPASMTSLGVGEESTTSRSQPGSTHST 2842
Query: 679 FSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKR 738
SP + T P L SE + ++ S + S T+ S+ S R +
Sbjct: 2843 VSPASTTT--------PGL-------SEESTTVYSS-SPGSTETTVFPRSTTTSVRGEEP 2886
Query: 739 KVFSPIRSEPRSPSHSMRTRSGRLSS-SELSPLTPPSSVSSSLSISVSPLATSALNPTFT 797
F S P S ++ T S +E S P S S+ + + + T
Sbjct: 2887 TTF---HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2943
Query: 798 FPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT-----PGSQTERGRNKD 852
FPS SG + R TS S+P+ L P T PGS T + +
Sbjct: 2944 FPS----SSGSTGTTLSPARSTTSGLV---GESTPSRLSPSSTETTTLPGSPTTPSLS-E 2995
Query: 853 KAPEELSKDRDADKSVEKDKSRERDREREKENKRE---SRKEKRKKGSEIQSSSALYPVG 909
K+ + R D ++ + E S S S + P
Sbjct: 2996 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055
Query: 910 RVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTT----AVKTKILIKKG 965
S + ++ S+ + G++ ++ H S D + L D T V+
Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 3115
Query: 966 RGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSS 997
G+L T T+ L++E T S PSSS
Sbjct: 3116 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 3147
Score = 48.9 bits (115), Expect = 1e-04
Identities = 130/590 (22%), Positives = 201/590 (34%), Gaps = 73/590 (12%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + F A S S + HSS +S ++ SS+ S + + I E +
Sbjct: 1170 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 1229
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
P +S++ + RS ++S S S + ST + T S+ P
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289
Query: 565 LLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILR-EPTFRWTSLK 623
T P + ++++ + T+ F ++T + G+ + P T+L
Sbjct: 1290 STTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTTFHSRPASTHTTLF 1344
Query: 624 HSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLH 683
S + A G P LT D+G S S + ++ SP
Sbjct: 1345 TEDSTTSGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 1402
Query: 684 SGTRFDMHKRSPLLRAPRFTP-------------SEAHSRIFESVTLPSNRTS-AGTSSS 729
S T + + +P +P T SE + + S P S A T+SS
Sbjct: 1403 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 1462
Query: 730 GVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLAT 789
GVS S S+P S + S S P T SS S ++SP +T
Sbjct: 1463 GVSEES------STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSS-QGSTEATLSPGST 1515
Query: 790 SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS-----SSPT-----PLFPWF 839
+A SL Q + + + T P + +S S+PT L
Sbjct: 1516 TA---------SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1566
Query: 840 TPGSQTERGRNKDKAP-EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSE 898
TP S T G ++ + D S + E SR
Sbjct: 1567 TPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTA----APVEVSTTYHSRPSSTPTTHF 1622
Query: 899 IQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKT 958
SS+ L GR E+ T S+ ATG + + TSV +G+ T
Sbjct: 1623 SASSTTL---GR-------SEESTTVHSSPGATGTALFPTRSA----TSVLVGEPTTSPI 1668
Query: 959 KILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
G+ E T L T L ++ T S+P S S +S S
Sbjct: 1669 ------SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS 1712
Score = 45.8 bits (107), Expect = 8e-04
Identities = 92/449 (20%), Positives = 153/449 (34%), Gaps = 70/449 (15%)
Query: 587 PPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKP 646
P T P+ S + + P + + T ++S RS + S A+ G+ K
Sbjct: 252 PKTSPITSASMETTALPGSTTTAGLSEKSTTFYSS---PRSPDRTLSPARTTSSGVSEKS 308
Query: 647 IFDNFRPPP---LTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFT 703
+ RP P + D G S TA+ + P + T +P P T
Sbjct: 309 TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHS---IPGSTDTTLSPGTTTPSSLGPEST 365
Query: 704 PSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRL- 762
+ ++ LP N T++G + +P+ S SP ++ S
Sbjct: 366 TFHSSPGYTKTTRLPDNTTTSGLLEAS-----------TPVHSSTGSPHTTLSPSSSTTH 414
Query: 763 -----------SSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLT--QSGES 809
SS + SP P + S+ + +S + ++ + PT F + S T S ES
Sbjct: 415 EGEPTTFQSWPSSKDTSP-APSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEES 473
Query: 810 AEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVE 869
+ P + P S++S E ++P + S
Sbjct: 474 TPVHSSPVATATTPPPARSATS-----------GHVEESTAYHRSPGSTQTMHFPESSTT 522
Query: 870 KDKSRERDREREKENKRESRKEKRKKGSEIQSSSAL----YPVGRVSKEKVVGEDVATSS 925
S +E+ K S +++AL Y S E D +T S
Sbjct: 523 SGHS--------EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTIS 574
Query: 926 SAKKATGRKKSSSHDSGTDIT------SVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPT 979
+ + SS T + SV +GD+T G++E T L T
Sbjct: 575 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPIS------SGSMETTALPGSTT 628
Query: 980 APSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
P L ++ T S+P S H +S+ S
Sbjct: 629 KPGLSEKSTTFYSSPRSPDTTHLPASMTS 657
Score = 45.8 bits (107), Expect = 8e-04
Identities = 102/450 (22%), Positives = 159/450 (35%), Gaps = 85/450 (18%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + FSA S + + HSS +++ +++PS ST S EE
Sbjct: 4505 STPTTHFSASSTTLGRSEESTTVHSSPVAT----ATTPSPARSTTSGLVEESTTYHSSPG 4560
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTS--SSPP 562
T +H PE+ + R + S S + ST + ++ TS SSP
Sbjct: 4561 STQTMH-------FPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 4613
Query: 563 PPLLTPPPPLQPAS----------SISDHTPWLMPP-------------TIPLAS----- 594
T P S S D T ++ P T P++S
Sbjct: 4614 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 4673
Query: 595 PFLPASTAPMQGKRKSIL------REPTFRW----TSLKHSRSEPQYFSS---------- 634
LP ST KS PT + T+L S SS
Sbjct: 4674 TALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 4733
Query: 635 AKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRS 694
A+ GL+ + + P + + + F +ASG + +R HS T +
Sbjct: 4734 ARSTTSGLVEES--TAYHSSPGSTQTMHFPESSTASGRSEESR---TSHSSTTHTISSPP 4788
Query: 695 PLLRAPRFTPSEAHSRIFESVT--LPSNRTSAGTS-SSGVSNRKRKRKVFSPIRSEPRSP 751
A P+ HS T P + T++G S S S+ +P+ P
Sbjct: 4789 STTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL------P 4842
Query: 752 SHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSP--------LATSALNPTFTFPSHSL 803
+H T SGR++ S ++P S ++ S + +P L +S+ +P T S+
Sbjct: 4843 AHF--TTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900
Query: 804 TQSGESAEKNQRPRKQTSAPAEPFSSSSPT 833
T S S E + S F +S+ T
Sbjct: 4901 TSSSISGEPTSLYSQAESTHTTAFPASTTT 4930
Score = 44.3 bits (103), Expect = 0.002
Identities = 139/627 (22%), Positives = 212/627 (33%), Gaps = 108/627 (17%)
Query: 441 ARLESTPNSRFSAPS--CGSSEKSSAASQH-----------------------SSQMSSD 475
+R STP + FSA S G SE+S+ +S +SS
Sbjct: 4252 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 4311
Query: 476 SSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSE 535
S+ +++ T+T + + RS + P S ES SR S+
Sbjct: 4312 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHT 4371
Query: 536 RSFGSRTTKKLSTLQSAPQQQTSSSPPP--------PLLTPPPPLQPASSISDHTPWLMP 587
+F S T T+ Q+ T+S P P T L P S+ +P
Sbjct: 4372 TAFPSST-----TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTE 4426
Query: 588 PTI----PLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLI 643
T+ AS L AST P T H+ P ++ +
Sbjct: 4427 TTLLPDNTTASGLLEAST-------------PVHSSTGSPHTTLSPAGSTTRQGESTTFQ 4473
Query: 644 RKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLR----A 699
P + P P T ++ G+ +S S T + S + A
Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4533
Query: 700 PRFTPSEAHSR----IFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSM 755
TPS A S + ES T S+ S T SN + R E + SHS
Sbjct: 4534 TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNT-------TSGRGEESTTSHSS 4586
Query: 756 RTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQR 815
T + +SS +P T + V S SP +T+ T FP S T SG S E
Sbjct: 4587 TTHT--ISS---APSTTSALVEEPTSYHSSPGSTA----TTHFPDSS-TTSGRSEESTAS 4636
Query: 816 ------------PRKQTSAPAEPFSSSSPTPLFPWFT---PGSQTERGRNKDKAPEELSK 860
P + T++ S++SP T PGS T G + +K+ S
Sbjct: 4637 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS-EKSTTFHSS 4695
Query: 861 DRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGED 920
+ S R E S S +S+++ G V +
Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS----GLVEESTAYHSS 4751
Query: 921 VATSSS-----AKKATGRKKSS--SHDSGTDITSVTLGDTTA-VKTKILIKKGRGNLEKT 972
++ + + A+GR + S SH S T S T+A V+ G++ T
Sbjct: 4752 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATT 4811
Query: 973 NLDLGPTAPSLEKEKTLCLSTPSSSTV 999
+ T +E T S+P ++ +
Sbjct: 4812 HFPESSTTSGRSEESTASHSSPDTNGI 4838
Score = 41.6 bits (96), Expect = 0.016
Identities = 134/557 (24%), Positives = 186/557 (33%), Gaps = 86/557 (15%)
Query: 3128 GLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPP---NISNPPSGL 3184
G T T GL+ T S S + L P S + T S P I+ P S
Sbjct: 269 GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 328
Query: 3185 LIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA 3244
+ GV + S+ T LS TPSS L P ST + +
Sbjct: 329 MPGVSQESTASHSIPGSTDTT-LSPGTTTPSS-----------------LGPESTTFHSS 370
Query: 3245 PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ 3304
P + N T S L + + S S H T+ S SS E P Q
Sbjct: 371 PGYTKTTRLPDNTTTSGLLEAST--PVHSSTGSPHTTL------SPSSSTTHEGEPTTFQ 422
Query: 3305 SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP-GH-- 3361
S S+DTS SG+ S S+ + T TT S++S GH
Sbjct: 423 SWPS-----------SKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 471
Query: 3362 ----------VTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPS---SGMFPQ 3408
T T P + G + A +S G Q + P S SG +
Sbjct: 472 ESTPVHSSPVATATTPPPARSATSGHVEE--STAYHRSPG-STQTMHFPESSTTSGHSEE 528
Query: 3409 LGT---------SQTPSTAAITAASSI-CVLPSTQTTGITAASPSGEADEHYQLQHVNQL 3458
T S TPST A A +S L ST+TT +S E + H +
Sbjct: 529 SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPD 588
Query: 3459 LASKT----GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTS--- 3511
+ T G S DS P S +T P S S+ +SP S
Sbjct: 589 AMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT 648
Query: 3512 ---PGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAH 3568
P SS S + + S S PG T +P G ++ SH ++
Sbjct: 649 THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP---GLSQESTASHSSPGPTDTT 705
Query: 3569 IPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQV-AVLPEVQVTQNPANEQ 3627
+ TT+ + G P S E + + +G + A +P T++P
Sbjct: 706 LSPGSTTASSLG---PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTL 762
Query: 3628 ESAEPKTVEEEESNFSS 3644
A T + E + F S
Sbjct: 763 SPAGSTTRQGESTTFHS 779
Score = 39.7 bits (91), Expect = 0.060
Identities = 90/398 (22%), Positives = 137/398 (34%), Gaps = 66/398 (16%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + FSA S + + HSS +++ +++PS ST S EE
Sbjct: 4698 STPTTHFSASSTTLGRSEESTTVHSSPVAT----ATTPSPARSTTSGLVEESTAYHSSPG 4753
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTS--SSPP 562
T +H PE+ + RS S S + ST + ++ TS SSP
Sbjct: 4754 STQTMH-------FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG 4806
Query: 563 PPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSL 622
T P S S+ + T +SP I P TS
Sbjct: 4807 SIATTHFPESSTTSGRSEES------TASHSSP-----------DTNGITPLPAHFTTSG 4849
Query: 623 KHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPL 682
+ + S Y S + AS + G +A + + L
Sbjct: 4850 RIAESTTFYISPGSM----------------------ETTLASTATTPGLSAKSTI---L 4884
Query: 683 HSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFS 742
+S +R SP E S ++ + + A T++SG+S +
Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQES------T 4938
Query: 743 PIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHS 802
S+P S ++ S SS TP S S+LS +VSP +T+ P + S +
Sbjct: 4939 TFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALS-TVSPASTTV--PGLSEESTT 4995
Query: 803 LTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT 840
S S E T + S+P P P FT
Sbjct: 4996 FYSSPGSTETTAFSHSNTMSIHS--QQSTPFPDSPGFT 5031
Score = 38.5 bits (88), Expect = 0.13
Identities = 82/416 (19%), Positives = 151/416 (36%), Gaps = 38/416 (9%)
Query: 443 LESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEE 502
+ S+P + + PS S S + ++ SS S + ++ST S SEE +
Sbjct: 4720 VHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT--SH 4777
Query: 503 RSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPP 562
S T + P + + E S S++ F +T ++ +S + SSP
Sbjct: 4778 SSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESST---TSGRSEESTASHSSPD 4834
Query: 563 PPLLTP-PPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTS 621
+TP P + I++ T + + P + + +T P + +IL
Sbjct: 4835 TNGITPLPAHFTTSGRIAESTTFYISPG-SMETTLASTATTPGLSAKSTIL--------- 4884
Query: 622 LKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSP 681
SRS Q S A + +P + + F + + SG + + F
Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEP--TSLYSQAESTHTTAFPASTTTSGLSQESTTFHS 4942
Query: 682 LHSGTRFDMHKRSPLLR--APRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRK 739
T + S A FT + S P++ T G S +
Sbjct: 4943 KPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYS---- 4998
Query: 740 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 799
SP +E + SHS + + S + +P P S + ++ + L T+ + T
Sbjct: 4999 --SPGSTETTAFSHS---NTMSIHSQQSTPF--PDSPGFTHTVLPATLTTTDIGQEST-- 5049
Query: 800 SHSLTQSGESAEKNQRPRKQTSAP--AEPFS-SSSPTPLFPWFTPGSQTERGRNKD 852
+ S ++ P + T++ EP + SP+P + P S + G ++
Sbjct: 5050 --AFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEE 5103
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 93.6 bits (231), Expect = 4e-18
Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 4/134 (2%)
Query: 3834 YRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR--EKYYDSKGIGCYMFRIDDSE 3891
+R+ G G+ K + AG+ +IEY G V+ + R E+Y++ C +D
Sbjct: 2145 FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYC--LNLDSGM 2202
Query: 3892 VVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDA 3951
V+D+ GN ARFINHSC+PNC + +++G I ++A++ + G ELTYDY F +
Sbjct: 2203 VIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNV 2262
Query: 3952 SNKLPCNCGAKKCR 3965
+ C CG +KCR
Sbjct: 2263 EKQQLCKCGFEKCR 2276
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 92.8 bits (229), Expect = 6e-18
Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Query: 3821 RHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYD-SKG 3879
R ++ V V + G GL +++ + V+EY G V+ + R K Y +K
Sbjct: 1542 RRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKN 1601
Query: 3880 IGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEE 3939
I Y + + E++DAT GN +RF+NHSCEPNC ++ ++GQ + F + + G E
Sbjct: 1602 IHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSE 1661
Query: 3940 LTYDYKFPIEDASNKLPCNCGAKKCRKFL 3968
LT+DY+F C CG+ CR +L
Sbjct: 1662 LTFDYQFQ-RYGKEAQKCFCGSANCRGYL 1689
Score = 32.3 bits (72), Expect = 9.6
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 843 SQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSS 902
SQTE+ + + RD + K+ R RER+ + K+ KEKRK+ S +
Sbjct: 2029 SQTEKENTTTERGRDAVGFRDQTPA---PKTPNRSRERDPD-KQTQNKEKRKRRSSLSPP 2084
Query: 903 SALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHD 940
S+ Y G +K D TS + R K S+ +
Sbjct: 2085 SSAYERG--TKRPDDRYDTPTSKKKVRIKDRNKLSTEE 2120
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 92.0 bits (227), Expect = 1e-17
Identities = 50/139 (35%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Query: 3831 VGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGI-GCYMFRIDD 3889
V ++R+ G GL K +I GE V EY G +I + R +Y I YM +D
Sbjct: 1675 VEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDK 1734
Query: 3890 SEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIE 3949
++DA GN ARF+NH C+PNC ++ +++G + +FA+ I G ELT++Y
Sbjct: 1735 DRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECL 1794
Query: 3950 DASNKLPCNCGAKKCRKFL 3968
+ K C CGA C FL
Sbjct: 1795 -GNGKTVCKCGAPNCSGFL 1812
Score = 44.7 bits (104), Expect = 0.002
Identities = 51/190 (26%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 1363 EKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGV---HRIRVDFKEDCEAENVWEMGG 1419
+KP +Q +A + N +SSK+ ++G HR KE E E V G
Sbjct: 1197 DKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVE-EGVEHDPG 1255
Query: 1420 L-------GILTSVPITPRVVCFLCASSGHVEFVYCQV-CCEPFHKFCLEENERPLEDQL 1471
+ G VC C G E + C+ CC FH CL E P +
Sbjct: 1256 MPASKKMQGERGGGAALKENVCQNCEKLG--ELLLCEAQCCGAFHLECLGLTEMPRGKFI 1313
Query: 1472 ENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCV 1531
N C C VC + + K+ L C YH EC+ PT + K + C+ +
Sbjct: 1314 CNECRTGIHTCFVCKQSGEDVKRCL-LPLCGKFYHEECVQKYPPT--VMQNKGFRCSLHI 1370
Query: 1532 RCKSCGSTTP 1541
C +C + P
Sbjct: 1371 -CITCHAANP 1379
Score = 33.9 bits (76), Expect = 3.3
Identities = 76/374 (20%), Positives = 139/374 (37%), Gaps = 45/374 (12%)
Query: 994 PSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCK--IEKSKSLKQTD-QPK 1050
PS+ + ST +DK P ++ SL KKA A C+ + + L++TD +P+
Sbjct: 1963 PSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSRPQ 2022
Query: 1051 AQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGN 1110
+ D + + + + R P D P A P R ++
Sbjct: 2023 PLDKVRDLAGSGTKSQSLVSSQR-------------PLDRPPAVAGP---RPQLSDKPSP 2066
Query: 1111 DDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC 1170
S + S ++PL P+ P P + + + G ++P +
Sbjct: 2067 VTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASP--RPQSLEKTSVPTGLRLPPPDRLL 2124
Query: 1171 TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEK--KDS 1228
KP+ R K + + + P + L + + KEK + ++ +
Sbjct: 2125 ITSSPKPQTSDRPTDKPHASLSQ----RLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSK 2180
Query: 1229 KESSVVKNVVD----------SSQKPTPSAREDPAPKKSSSEPPPR--KPVEEKSEEGNV 1276
+++V +++D S + TP A E +SSS P + + E+G V
Sbjct: 2181 NRAALVMDLIDLTPRQKERAASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCV 2240
Query: 1277 SAPGPESKQATTPASR--KSSKQVSQPALVIPPQPPTTGPPRKEVPKTT--PSEPKKKQP 1332
S P S +A P+ ++ K ++Q L+ QPP + + + S ++ P
Sbjct: 2241 SDPLQTSGKAAAPSEDPWQAVKSLTQARLL--SQPPAKAFLYEPTTQASGRASAGAEQTP 2298
Query: 1333 PPPESGPEQSKQKK 1346
P P KQ K
Sbjct: 2299 GPLSQSPGLVKQAK 2312
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 92.0 bits (227), Expect = 1e-17
Identities = 50/139 (35%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Query: 3831 VGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGI-GCYMFRIDD 3889
V ++R+ G GL K +I GE V EY G +I + R +Y I YM +D
Sbjct: 1944 VEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDK 2003
Query: 3890 SEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIE 3949
++DA GN ARF+NH C+PNC ++ +++G + +FA+ I G ELT++Y
Sbjct: 2004 DRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECL 2063
Query: 3950 DASNKLPCNCGAKKCRKFL 3968
+ K C CGA C FL
Sbjct: 2064 -GNGKTVCKCGAPNCSGFL 2081
Score = 44.7 bits (104), Expect = 0.002
Identities = 51/190 (26%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 1363 EKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGV---HRIRVDFKEDCEAENVWEMGG 1419
+KP +Q +A + N +SSK+ ++G HR KE E E V G
Sbjct: 1466 DKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVE-EGVEHDPG 1524
Query: 1420 L-------GILTSVPITPRVVCFLCASSGHVEFVYCQV-CCEPFHKFCLEENERPLEDQL 1471
+ G VC C G E + C+ CC FH CL E P +
Sbjct: 1525 MPASKKMQGERGGGAALKENVCQNCEKLG--ELLLCEAQCCGAFHLECLGLTEMPRGKFI 1582
Query: 1472 ENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCV 1531
N C C VC + + K+ L C YH EC+ PT + K + C+ +
Sbjct: 1583 CNECRTGIHTCFVCKQSGEDVKRCL-LPLCGKFYHEECVQKYPPT--VMQNKGFRCSLHI 1639
Query: 1532 RCKSCGSTTP 1541
C +C + P
Sbjct: 1640 -CITCHAANP 1648
Score = 33.9 bits (76), Expect = 3.3
Identities = 76/374 (20%), Positives = 139/374 (37%), Gaps = 45/374 (12%)
Query: 994 PSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCK--IEKSKSLKQTD-QPK 1050
PS+ + ST +DK P ++ SL KKA A C+ + + L++TD +P+
Sbjct: 2232 PSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSRPQ 2291
Query: 1051 AQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGN 1110
+ D + + + + R P D P A P R ++
Sbjct: 2292 PLDKVRDLAGSGTKSQSLVSSQR-------------PLDRPPAVAGP---RPQLSDKPSP 2335
Query: 1111 DDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC 1170
S + S ++PL P+ P P + + + G ++P +
Sbjct: 2336 VTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASP--RPQSLEKTSVPTGLRLPPPDRLL 2393
Query: 1171 TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEK--KDS 1228
KP+ R K + + + P + L + + KEK + ++ +
Sbjct: 2394 ITSSPKPQTSDRPTDKPHASLSQ----RLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSK 2449
Query: 1229 KESSVVKNVVD----------SSQKPTPSAREDPAPKKSSSEPPPR--KPVEEKSEEGNV 1276
+++V +++D S + TP A E +SSS P + + E+G V
Sbjct: 2450 NRAALVMDLIDLTPRQKERAASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCV 2509
Query: 1277 SAPGPESKQATTPASR--KSSKQVSQPALVIPPQPPTTGPPRKEVPKTT--PSEPKKKQP 1332
S P S +A P+ ++ K ++Q L+ QPP + + + S ++ P
Sbjct: 2510 SDPLQTSGKAAAPSEDPWQAVKSLTQARLL--SQPPAKAFLYEPTTQASGRASAGAEQTP 2567
Query: 1333 PPPESGPEQSKQKK 1346
P P KQ K
Sbjct: 2568 GPLSQSPGLVKQAK 2581
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 89.7 bits (221), Expect = 5e-17
Identities = 60/171 (35%), Positives = 92/171 (53%), Gaps = 24/171 (14%)
Query: 3821 RHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEM--VIEYAGNVIRSIQTDKREKYYDSK 3878
R ++K ++ ++ ++R+ +GRG K + M V+EY G VI S + ++R ++YD+K
Sbjct: 182 RIVQKGTQYSLCIFRTS-NGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 240
Query: 3879 GIGCYMFRID---DSEVVDATMHGNAARFINHSCEPNCYSRVINIDG----QKHIVIFAM 3931
GI Y+F +D D VDA +GN + F+NHSC+PN + ID I +F+
Sbjct: 241 GI-TYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFST 299
Query: 3932 RKIYRGEELTYDYKFP-----IEDASNKLP--------CNCGAKKCRKFLN 3969
R I GEELT+DY+ D+ + P C CGA CR +LN
Sbjct: 300 RTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 89.0 bits (219), Expect = 9e-17
Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898
G GL KR+I GE V EY G +I + R K+ I YM ID ++DA
Sbjct: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
Query: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958
GN +RF+NHSC+PNC + ++G + +FA+ I G ELT++Y + K C
Sbjct: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
Query: 3959 CGAKKCRKFL 3968
CGA C FL
Sbjct: 1193 CGASNCSGFL 1202
Score = 36.6 bits (83), Expect = 0.51
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491
VC LC G + + C+ CC FH CL + RP + C C VC
Sbjct: 669 VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
Query: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541
K+ + +C YH C+ YP + + + C CV C + + P
Sbjct: 727 VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
Score = 33.5 bits (75), Expect = 4.3
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493
CF C G + + C + +H CL +RP W C C VCG+ +
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
Query: 1494 QLLECNKCRNSYHPE 1508
C+ C NS+ E
Sbjct: 1296 ----CHLCPNSFCKE 1306
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 89.0 bits (219), Expect = 9e-17
Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898
G GL KR+I GE V EY G +I + R K+ I YM ID ++DA
Sbjct: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
Query: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958
GN +RF+NHSC+PNC + ++G + +FA+ I G ELT++Y + K C
Sbjct: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
Query: 3959 CGAKKCRKFL 3968
CGA C FL
Sbjct: 1193 CGASNCSGFL 1202
Score = 36.6 bits (83), Expect = 0.51
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491
VC LC G + + C+ CC FH CL + RP + C C VC
Sbjct: 669 VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
Query: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541
K+ + +C YH C+ YP + + + C CV C + + P
Sbjct: 727 VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
Score = 33.5 bits (75), Expect = 4.3
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493
CF C G + + C + +H CL +RP W C C VCG+ +
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
Query: 1494 QLLECNKCRNSYHPE 1508
C+ C NS+ E
Sbjct: 1296 ----CHLCPNSFCKE 1306
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 89.0 bits (219), Expect = 9e-17
Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898
G GL KR+I GE V EY G +I + R K+ I YM ID ++DA
Sbjct: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
Query: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958
GN +RF+NHSC+PNC + ++G + +FA+ I G ELT++Y + K C
Sbjct: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
Query: 3959 CGAKKCRKFL 3968
CGA C FL
Sbjct: 1193 CGASNCSGFL 1202
Score = 36.6 bits (83), Expect = 0.51
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491
VC LC G + + C+ CC FH CL + RP + C C VC
Sbjct: 669 VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
Query: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541
K+ + +C YH C+ YP + + + C CV C + + P
Sbjct: 727 VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
Score = 33.5 bits (75), Expect = 4.3
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493
CF C G + + C + +H CL +RP W C C VCG+ +
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
Query: 1494 QLLECNKCRNSYHPE 1508
C+ C NS+ E
Sbjct: 1296 ----CHLCPNSFCKE 1306
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 89.0 bits (219), Expect = 9e-17
Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898
G GL KR+I GE V EY G +I + R K+ I YM ID ++DA
Sbjct: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
Query: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958
GN +RF+NHSC+PNC + ++G + +FA+ I G ELT++Y + K C
Sbjct: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
Query: 3959 CGAKKCRKFL 3968
CGA C FL
Sbjct: 1193 CGASNCSGFL 1202
Score = 36.6 bits (83), Expect = 0.51
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491
VC LC G + + C+ CC FH CL + RP + C C VC
Sbjct: 669 VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
Query: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541
K+ + +C YH C+ YP + + + C CV C + + P
Sbjct: 727 VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
Score = 33.5 bits (75), Expect = 4.3
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493
CF C G + + C + +H CL +RP W C C VCG+ +
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
Query: 1494 QLLECNKCRNSYHPE 1508
C+ C NS+ E
Sbjct: 1296 ----CHLCPNSFCKE 1306
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 84.7 bits (208), Expect = 2e-15
Identities = 295/1423 (20%), Positives = 473/1423 (33%), Gaps = 244/1423 (17%)
Query: 2226 SVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSS 2285
S +T+G + + + H S+T+ +TS S+L T T +S + G S
Sbjct: 6 SSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSE 65
Query: 2286 SEMKQSSASDLVSKSSSLKGEKTKVLSSKS-----SEGSAHNVAYPGIPKLAPQVHNTTS 2340
S+ D ++ + G VL S S GS A PG +TT
Sbjct: 66 ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG---------STTK 116
Query: 2341 RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVK 2400
L+ E S+ +SS + HL + + + ++ S S
Sbjct: 117 PGLS--------EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG 168
Query: 2401 TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNL 2460
+ + G+S S+ + G + + L PG T G
Sbjct: 169 STTMPGLSQESTASHSSPGPTD----------------------TTLSPGSTTASSLG-- 204
Query: 2461 KPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTV 2520
PEY + + + G+ +A M V S R+
Sbjct: 205 ----------PEYTTFHSRPGSTETTLLPDNTTASGLLEAS-MPVHSST--------RSP 245
Query: 2521 KVTLTPL---KMENESQSKNALKESSPASPLQIESTSP-TEPISASE-NPGDGPVAQPSP 2575
TL+P + ES + ++ S P +TS EP + S +P P S
Sbjct: 246 HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 305
Query: 2576 NNT-SCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPL 2634
+T S +S Y + P + + P+ G S + S+ ++
Sbjct: 306 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE-------ESTTSHSSTTHTISSA 358
Query: 2635 YGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE 2694
S E+ Y SS G D ST+ S E
Sbjct: 359 PSTTSALVEEPTSYHSSPGSTATTHFP--------DSSTT---------------SGRSE 395
Query: 2695 ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK 2754
E ASH+ LP S V G + + +++ + +++ +P +E
Sbjct: 396 ESTASHSSQDATGTIVLPARSTTS-VLLGESTTSPISSGSMETTALPGSTTTPGLSE--- 451
Query: 2755 IDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTST 2814
+S+ H + ++S T E +S HT+
Sbjct: 452 --------------RSTTFHSSP--RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA 495
Query: 2815 PSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSEL 2874
D + S S ++D +LP+ + PS ++ S S++
Sbjct: 496 FPDSTTTPGLSRHSTTSHSSPGSTDT--TLLPAS----TTTSGPSQESTTSHSSSGSTDT 549
Query: 2875 -LNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSV 2933
L+ G L +E F TT DS+ SS I E + S +
Sbjct: 550 ALSPGSTTALSFGQESTT--FHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTT 606
Query: 2934 LTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASS---ESDPALLSPGVDPTPEGHMT 2990
L+ S T P A + T + S A++ ES SPG PT
Sbjct: 607 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT----- 661
Query: 2991 PDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNS 3050
HF P S GH + +S P S + S
Sbjct: 662 --HF-------------PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 706
Query: 3051 TDSPGPSQISNAAVQTTPPHL---------KPATEKLIVVNQNMQPLYVLQTLPNGVTQK 3101
SPG ++I+ TT P L P + + +M L V + +Q
Sbjct: 707 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 766
Query: 3102 IQLTSSVS----STPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMS 3157
S+VS +TP + E +T+V G T ++FP ++ +
Sbjct: 767 GSTHSTVSPASTTTPGLSEESTTVYSSSRGS------------TETTVFPHSTTTSVHGE 814
Query: 3158 HHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSG 3217
HS PA+T ++ S SGL P S +S +T L T+ T G
Sbjct: 815 EPTTFHSRPASTHTTLFTEDST-TSGLTEESTAFPG-----SPASTQTGLPATLTTADLG 868
Query: 3218 LKKRPISRLQTRKNKKLAPS-STPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNT 3276
+ KL+P+ ST S + S ++ + + LP P+ L +T
Sbjct: 869 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 928
Query: 3277 SSHRTV----PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQD------TSHL 3326
+ + + + + +S E + G T TA ST + D TSH
Sbjct: 929 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 988
Query: 3327 TSGSVSG-LASSSSVLNVVSMQTTT-----TPTSSASVPGHVTLTNPRLLGTP---DIGS 3377
+ GS L+ S+ + + Q+TT T + +P + TP GS
Sbjct: 989 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048
Query: 3378 ISNLLIKASQQSLGIQDQPVAL---PPSSGMFPQ-LGTSQTPSTAAITAASSICVLPSTQ 3433
+ L AS S G+Q++ P SS P GT+ P + T S ST
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR---PSSTP 1105
Query: 3434 TTGITAASPS-GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNS 3492
TT +A+S + G ++E T +HSS +A P S + V P +
Sbjct: 1106 TTHFSASSTTLGRSEE-------------STTVHSSPGATGTALFPTRSATSVLVGEPTT 1152
Query: 3493 MGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNG 3552
+ ++A+ S T+ G S S + +SP P T T G
Sbjct: 1153 SPISSGSTETTALPGSTTTAGLSEKSTTF---YSSPRSPDTTLSPAST------TSSGVS 1203
Query: 3553 KKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTAS 3595
++ SH R S+ TT+ T PG Q+ TAS
Sbjct: 1204 EESTTSHSRPGST-------HTTAFPGSTTMPG--VSQESTAS 1237
Score = 71.6 bits (174), Expect = 1e-11
Identities = 284/1418 (20%), Positives = 486/1418 (34%), Gaps = 197/1418 (13%)
Query: 2085 STVEHDENRTIAHSPTSFTESSSKESQNTAEIISPP-----SPDRPP------HSQTSG- 2132
ST E+ T HS S ++ T+ + P SP P S TSG
Sbjct: 254 STTRQGESTTF-HSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGL 312
Query: 2133 ---SCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRS 2189
S YH +P + T P G + T+H SS +
Sbjct: 313 VEESTTYH--------SSPGSTQTMHFPESDTTSGRGEESTTSH----------SSTTHT 354
Query: 2190 IGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGP 2249
I S +TS+L + + SP T T+ ++ ++ + +T SS ++ P
Sbjct: 355 ISSAPSTTSALVEEPTSYH-SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 413
Query: 2250 LNSSTS--LGQNTST---SSNLQRTVVTVGNKNSHLDGSSSS--EMKQSSASDLVSKSSS 2302
S+TS LG++T++ S +++ T + L S++ +S A+ L S++
Sbjct: 414 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 473
Query: 2303 LKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSK 2362
G + +S+S GS H A+P +TT+ L+ S + P S +
Sbjct: 474 SSGVSEESTTSRSRPGSTHTTAFP---------DSTTTPGLSRHSTTSHSSPGSTDTTL- 523
Query: 2363 EALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSS 2422
L +ST S +SS DT + + +S G S
Sbjct: 524 ---------LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALS---------FGQES 565
Query: 2423 RDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLT-PEYMGQRPCNN 2481
+ F + +S +E G+ + T P G+
Sbjct: 566 TTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 625
Query: 2482 VSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQS-KNALK 2540
+ P P VE S ++P + T P S K+ +
Sbjct: 626 THPASTH----TTPSPPSTATAPVEESTTYHRSP--GSTPTTHFPASSTTSGHSEKSTIF 679
Query: 2541 ESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQ-----------DSQSNNYQ 2589
SSP T+P+ S + G+ ++ SP +T S +
Sbjct: 680 HSSP----DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 735
Query: 2590 NLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYS 2649
+ P + P G + S + T G+ EE YS
Sbjct: 736 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL---SEESTTVYS 792
Query: 2650 SSTGKKRG---KRSAEGQVDGADDLS-TSDEDDLYYYNFTRTVISSGGEERLASHNLFRE 2705
SS G S V G + + S + FT +SG E +
Sbjct: 793 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852
Query: 2706 EEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKE 2765
Q LP + L D G ES T +++ +++ +G + P
Sbjct: 853 STQTGLP--ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL--VGESTPSRLSPSS 908
Query: 2766 HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYN 2825
T + G P + + + D+ + ++ S +ST S T+
Sbjct: 909 TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-SHSQPGSTHT 967
Query: 2826 TELLKS--DSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGL 2883
T S SD + + + + + +LG+ + S + L
Sbjct: 968 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1027
Query: 2884 DSNREKDMGLFEVFSQQLPTTEPVDSSV--SSSISAEEQFELPLELPSDLSVLTTRSPTV 2941
D GL E + +T + +++ +SS SA Q E S TT SP
Sbjct: 1028 DDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPG 1085
Query: 2942 PSQNPSRLAVISDSGEKRVTITEKSVASS------ESDPALLSPGVDPTPEGHMTPDHFI 2995
+ P ++ S T S +S+ ES SPG T + P
Sbjct: 1086 TTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA---LFPTRSA 1142
Query: 2996 QGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPG 3055
+ + +SP + G L +++T GL + + P++T SP
Sbjct: 1143 TSVLVGEPTTSP----ISSGSTETTALPGSTTTAGLS---EKSTTFYSSPRSPDTTLSPA 1195
Query: 3056 PSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVM 3115
+ S + ++T H +P + + T+P GV+Q + T+S SS S
Sbjct: 1196 STTSSGVSEESTTSHSRPGSTHTTAFPGS-------TTMP-GVSQ--ESTASHSSPGST- 1244
Query: 3116 ETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPP 3175
T L+P T+ SL P ++ HS P +T+++ P
Sbjct: 1245 ----------------DTTLSPGSTTASSLGPESTT----------FHSSPGSTETTLLP 1278
Query: 3176 NISNPPSGLLIGVQP------PPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTR 3229
+ + SGLL P P L + S+ R STT + S P T
Sbjct: 1279 D-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1337
Query: 3230 KNKKLAPSS--TPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIK 3287
+L+ +S +PS+ + ++ T + + H S + + + + T +++
Sbjct: 1338 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 1397
Query: 3288 RSKSSIMYFEPAPLLPQSVG-GTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSM 3346
S + + +P Q++ ++TA+G S S+ + T+ ++S S++S L
Sbjct: 1398 ESTA----YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL----- 1448
Query: 3347 QTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQP--VALPPSSG 3404
PTS S PG + T+ P+ + S S++S P + P
Sbjct: 1449 --VEEPTSYHSSPGSIATTH-----FPESSTTSG----RSEESTASHSSPDTNGITPLPA 1497
Query: 3405 MFPQLGTSQTPSTAAITAASSICVLPSTQTT-GITAAS 3441
F G +T I+ S L ST TT G++A S
Sbjct: 1498 HFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKS 1535
Score = 63.2 bits (152), Expect = 5e-09
Identities = 180/846 (21%), Positives = 312/846 (36%), Gaps = 110/846 (13%)
Query: 2908 DSSVSSSISAEEQFELPLELPS-DLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKS 2966
+S+ A Q LP L + DL +T P+ ++L+ + V + S
Sbjct: 843 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 902
Query: 2967 VASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNS 3026
S S PG TP F D SP + G +++ + +
Sbjct: 903 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP---ATTTSSGVSEESSTSH 959
Query: 3027 STPG----LQVPVSPTVPIQNQKYVPN--------STDSPGPSQISNAAVQTTPPHLKPA 3074
S PG P S T +Q+ + +T SPG + S+ Q+T H P
Sbjct: 960 SQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 1019
Query: 3075 -TEKLIVVNQNMQPLYVLQTLP-NGVTQKIQLTSSVSST---------------PSVMET 3117
TE ++ + + V + P + T + T + +S+ PS +T
Sbjct: 1020 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDT 1079
Query: 3118 NTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQH-LHSFPAATQSSFPPN 3176
S G + ++T + ++ + SAS L S +HS P AT ++ P
Sbjct: 1080 TPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPT 1139
Query: 3177 ISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAP 3236
S + +L+G +P P + S S++ T L + T K + L+P
Sbjct: 1140 RS--ATSVLVG-EPTTSP--ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1194
Query: 3237 SSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSH---RTVPNIIKRSKSSI 3293
+ST S S V T + P GS +T++ T+P + + S +S
Sbjct: 1195 ASTTS----SGVSEESTTSHSRP------------GSTHTTAFPGSTTMPGVSQESTAS- 1237
Query: 3294 MYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT 3353
S G T T + ST + ++ S S+ + L + TT +
Sbjct: 1238 ---------HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL--LPDNTTASGL 1286
Query: 3354 SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSS-GMFPQLGTS 3412
AS P H + +P +P GS + + QS + PP++ F +L T+
Sbjct: 1287 LEASTPVHSSTGSPHTTLSP-AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345
Query: 3413 Q--TPSTAAIT--AASSICVLPSTQTTGI------TAASPSGEADEHYQLQHVNQLLASK 3462
+PS+ T +ASS + S ++T + TA +PS L + S
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1405
Query: 3463 TGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSG 3522
G + +S++ S ++T + + + + +SA+ PTS SP S ++
Sbjct: 1406 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATT 1465
Query: 3523 QRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAH------IPDQETTS 3576
S + G + + T P NG +H TS A P T+
Sbjct: 1466 HFPESSTTSG--RSEESTASHSSP--DTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 1521
Query: 3577 LTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVE 3636
L S TPG A+ S + G+P T PA+ S E
Sbjct: 1522 LASTATTPGLSAK-----STILYTSDLVGEPTTFYISPSPTYTTLFPASSSTSG---LTE 1573
Query: 3637 EEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDK 3696
E + +SP + E++ + P+K +++ G +++ +++ T+K
Sbjct: 1574 ESTTFHTSPSFTSTIVSTESLETLAPETPEK-----LNATLGM-----TVKVTYRNFTEK 1623
Query: 3697 VQEARS 3702
+ +A S
Sbjct: 1624 MNDASS 1629
Score = 62.0 bits (149), Expect = 1e-08
Identities = 139/615 (22%), Positives = 222/615 (36%), Gaps = 91/615 (14%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSS------DSSRSSSPSVDTSTDSQASEEI-- 496
ST ++ SAPS S+ S HSS S+ DSS +S S + ST S +S++
Sbjct: 350 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS-EESTASHSSQDATG 408
Query: 497 ----------QVLPEERSDTPEVHPPLPISQSPENESN---DRRSRRYSVSERSFGSRTT 543
VL E + +P + + P + + RS + S RS + +
Sbjct: 409 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 468
Query: 544 KKLSTLQSAPQQQTSSSPPP--------PLLTPPPPLQPASSISDHTPWLMPPTIPLASP 595
+T ++ T+S P P T P L S+ S +P T+
Sbjct: 469 PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL----- 523
Query: 596 FLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAK-----YAKEGLIRKPIFDN 650
LPAST ++S + T S S + ++ G +F
Sbjct: 524 -LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF-- 580
Query: 651 FRPPPLTPEDVGFASGFSASGTAASARLFSPLHS--------GTRFDMHKRSPLLRAPRF 702
P T + AS S T + SP S T F H S
Sbjct: 581 --PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST--HTTPS 636
Query: 703 TPSEAHSRIFESVTLPSNRTSAGTS----SSGVSNRKRKRKVF--SPIRSEPR-SPSHSM 755
PS A + + ES T + S T+ SS S K +F SP S S +HS
Sbjct: 637 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 696
Query: 756 RTRSGRLSSSELSP------LTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGES 809
+ G ++S +SP P S+ + LS + + +S +PT T S+T G
Sbjct: 697 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 756
Query: 810 AEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVE 869
E T++ ++P S+ S +P S T G +++ S R + ++
Sbjct: 757 EES-------TTSRSQPGSTHSTV------SPASTTTPGLSEESTTV-YSSSRGSTETTV 802
Query: 870 KDKSRERDREREKENKRESRKEKR--------KKGSEIQSSSALYPVGRVSKEKVVGEDV 921
S E+ SR S + S +P S + + +
Sbjct: 803 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 862
Query: 922 ATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAP 981
T+ +++T SSS +GT ++ + V + + E T L PT P
Sbjct: 863 TTADLGEEST-TFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 921
Query: 982 SLEKEKTLCLSTPSS 996
SL ++ T ++P S
Sbjct: 922 SLSEKSTTFYTSPRS 936
Score = 56.6 bits (135), Expect = 5e-07
Identities = 283/1354 (20%), Positives = 436/1354 (32%), Gaps = 247/1354 (18%)
Query: 2081 PDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVIS 2140
PD ++T E T +HS T + +++T ++ S P +SGS
Sbjct: 385 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP---ISSGS------- 434
Query: 2141 KVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSL 2200
T PG P + T H S RS + S+
Sbjct: 435 ----------METTALPGSTTTPGLSERSTTFH-----------SSPRSPATTLSPASTT 473
Query: 2201 SPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGT---ATDLESSAKVVDHVLGPLNSSTSLG 2257
S S+ S R G+T++ S +T G +T SS D L P +++TS
Sbjct: 474 SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 533
Query: 2258 QNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSE 2317
ST+S+ GS+ + + S + L S E T + S+
Sbjct: 534 SQESTTSHSS-------------SGSTDTALSPGSTTAL-----SFGQEST---TFHSNP 572
Query: 2318 GSAHNVAYP------GIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLH 2371
GS H +P GI + + +VH++T S P
Sbjct: 573 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG---------------- 616
Query: 2372 LRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK 2431
L+G+ H ST + S P T + + S H +SS
Sbjct: 617 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS----TTSGH 672
Query: 2432 SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKG 2491
S K T S P + G G+ + +S +
Sbjct: 673 SEKSTIFHSSPDASGTTPSSAHSTTSGR---------------GESTTSRISPG--STEI 715
Query: 2492 LSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKM----------ENESQSKNALKE 2541
++PG P + E S +PR T TL+P M + SQ +
Sbjct: 716 TTLPGSTTTPGLS-EASTTFYSSPRSPT--TTLSPASMTSLGVGEESTTSRSQPGSTHST 772
Query: 2542 SSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLP 2601
SPAS + + + +S P TS + + + P +
Sbjct: 773 VSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 832
Query: 2602 DGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSS--STGKK--RG 2657
+ +P A ++ GL GEE F SS STG K
Sbjct: 833 EDSTTSGLTEESTAFPGSPASTQT----GLPATLTTADLGEESTTFPSSSGSTGTKLSPA 888
Query: 2658 KRSAEGQV------------------DGADDLSTSDEDDLYYYNFTR---------TVIS 2690
+ + G V G+ + E +Y R T S
Sbjct: 889 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 948
Query: 2691 SG-GEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENG 2749
SG EE SH+ P D T SD S TT SSQ G
Sbjct: 949 SGVSEESSTSHSQPGSTHTTAFP--------DSTTTSDLSQEPTTSHSSQ-----GSTEA 995
Query: 2750 TENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRR 2809
T + G++ SS G + + T +EA + S+
Sbjct: 996 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD-------DTITSGLVEASTPTHSSTGS 1048
Query: 2810 VHTS-TPSDKNLL----DTYNTELLKSDSDNNNSDDCGNILPSDIMDFV---LKNTP--- 2858
+HT+ TP+ ++ + S SD S P ++ +TP
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108
Query: 2859 ---SMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSI 2915
S LG S ES++ G L R L PTT P+ SS S+
Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE-----PTTSPI-SSGSTET 1162
Query: 2916 SAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPA 2975
+A L S+ S SP P S + S SG + T S S A
Sbjct: 1163 TALPGSTTTAGL-SEKSTTFYSSPRSPDTTLSPASTTS-SGVSEESTTSHSRPGSTHTTA 1220
Query: 2976 LLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPV 3035
P T H G D SP GS + T +SS + +
Sbjct: 1221 FPGSTTMPGVSQESTASHSSPG--STDTTLSP--GSTTASSLGPESTTFHSSPGSTETTL 1276
Query: 3036 SP-----------TVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQN 3084
P + P+ + P++T SP S ++T P+++ +
Sbjct: 1277 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG--ESTTFQSWPSSKDTMPAPPT 1334
Query: 3085 MQPLYV-LQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQ 3143
+V L T +G S SSTP+ + +S +G TT + + T+
Sbjct: 1335 TTSAFVELSTTSHG---------SPSSTPTTHFSASST--TLGRSEESTTVHSSPVATAT 1383
Query: 3144 SLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ 3203
+ P+ S + HS P +TQ+ P S+ SG SE S
Sbjct: 1384 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE-SSTASGR--------------SEES- 1427
Query: 3204 RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP 3263
RT S+T T SS P S + + S+P +IA + + T +
Sbjct: 1428 RTSHSSTTHTISS-----PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTA 1482
Query: 3264 NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDT 3323
+H S G +H T I ++S+ Y P S+ T A+ A T +S +
Sbjct: 1483 SHSSPDTNGITPLPAHFTTSGRI--AESTTFYISPG-----SMETTLASTATTPGLSAKS 1535
Query: 3324 SHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSAS 3357
+ L + + G ++ ++ TT P SS++
Sbjct: 1536 TILYTSDLVG-EPTTFYISPSPTYTTLFPASSST 1568
Score = 48.9 bits (115), Expect = 1e-04
Identities = 130/590 (22%), Positives = 201/590 (34%), Gaps = 73/590 (12%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
STP + F A S S + HSS +S ++ SS+ S + + I E +
Sbjct: 657 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 716
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPP 564
P +S++ + RS ++S S S + ST + T S+ P
Sbjct: 717 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 776
Query: 565 LLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILR-EPTFRWTSLK 623
T P + ++++ + T+ F ++T + G+ + P T+L
Sbjct: 777 STTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTTFHSRPASTHTTLF 831
Query: 624 HSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLH 683
S + A G P LT D+G S S + ++ SP
Sbjct: 832 TEDSTTSGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 889
Query: 684 SGTRFDMHKRSPLLRAPRFTP-------------SEAHSRIFESVTLPSNRTS-AGTSSS 729
S T + + +P +P T SE + + S P S A T+SS
Sbjct: 890 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 949
Query: 730 GVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLAT 789
GVS S S+P S + S S P T SS S ++SP +T
Sbjct: 950 GVSEES------STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSS-QGSTEATLSPGST 1002
Query: 790 SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS-----SSPT-----PLFPWF 839
+A SL Q + + + T P + +S S+PT L
Sbjct: 1003 TA---------SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1053
Query: 840 TPGSQTERGRNKDKAP-EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSE 898
TP S T G ++ + D S + E SR
Sbjct: 1054 TPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTA----APVEVSTTYHSRPSSTPTTHF 1109
Query: 899 IQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKT 958
SS+ L GR E+ T S+ ATG + + TSV +G+ T
Sbjct: 1110 SASSTTL---GR-------SEESTTVHSSPGATGTALFPTRSA----TSVLVGEPTTSPI 1155
Query: 959 KILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
G+ E T L T L ++ T S+P S S +S S
Sbjct: 1156 ------SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS 1199
Score = 48.1 bits (113), Expect = 2e-04
Identities = 79/336 (23%), Positives = 124/336 (36%), Gaps = 50/336 (14%)
Query: 704 PSEAHSRIFE-SVTLP--SNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSG 760
P H+ F S T+P S ++A SS G ++ SP + S T
Sbjct: 158 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDT-----TLSPGSTTASSLGPEYTTFHS 212
Query: 761 RLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTF-PSHSLTQSGESAEKNQRPRKQ 819
R S+E + L P ++ +S L + P+ +S +P T P+ S T+ GES + P +
Sbjct: 213 RPGSTETT-LLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSK 271
Query: 820 TSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKS------ 873
+ PA P ++S+ F S T G +S VE+ +
Sbjct: 272 DTRPAPPTTTSA-------FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG 324
Query: 874 ---------RERDREREKENKRESRKEKRKKGSEIQSSSAL------YPVGRVSKEKVVG 918
+ R +E+ S ++SAL Y S
Sbjct: 325 STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF 384
Query: 919 EDVATSSSAKKATGRKKSSSHDSGTDI------TSVTLGDTTAVKTKILIKKGRGNLEKT 972
D +T+S + + SS +GT + TSV LG++T G++E T
Sbjct: 385 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS------SGSMETT 438
Query: 973 NLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
L T P L + T S+P S S +S S
Sbjct: 439 ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 474
Score = 47.4 bits (111), Expect = 3e-04
Identities = 122/590 (20%), Positives = 199/590 (33%), Gaps = 60/590 (10%)
Query: 448 NSRFSAPSCGSSEKS---SAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEE-- 502
+S S S GS++ + ++ + S +S SSS S DT+ ++ + E
Sbjct: 508 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 567
Query: 503 -RSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSS- 560
S+ H L + + + +R +S S GS T ++P Q S+
Sbjct: 568 FHSNPGSTHTTLFPDSTTSSGIVEASTRVHS----STGSPRTTLSPASSTSPGLQGESTA 623
Query: 561 ----PPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILRE-P 615
P TP PP + + + T + P + F +ST ++ +I P
Sbjct: 624 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 683
Query: 616 TFRWT--SLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTA 673
T S HS + + S+ G P T + AS S
Sbjct: 684 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL----PGSTTTPGLSEASTTFYSSPR 739
Query: 674 ASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSN 733
+ SP S T + + S R+ P HS + + T + T+ S
Sbjct: 740 SPTTTLSPA-SMTSLGVGEESTTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSR 795
Query: 734 RKRKRKVF-------------SPIRSEPRSPSHSMRTRSGRLSS-SELSPLTPPSSVSSS 779
+ VF + S P S ++ T S +E S P S S+
Sbjct: 796 GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 855
Query: 780 LSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWF 839
+ + + TFPS SG + K R TS S+P+ L P
Sbjct: 856 TGLPATLTTADLGEESTTFPS----SSGSTGTKLSPARSTTSGLV---GESTPSRLSPSS 908
Query: 840 T-----PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRE---SRKE 891
T PGS T + +K+ + R D ++ + E S
Sbjct: 909 TETTTLPGSPTTPSLS-EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 967
Query: 892 KRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLG 951
S S + P S + ++ S+ + G++ ++ H S D + L
Sbjct: 968 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1027
Query: 952 DTTA----VKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSS 997
D T V+ G+L T T+ L++E T S PSSS
Sbjct: 1028 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 1077
Score = 47.0 bits (110), Expect = 4e-04
Identities = 214/1056 (20%), Positives = 350/1056 (33%), Gaps = 143/1056 (13%)
Query: 2081 PDINSTVEHDENRTIAHSP-----TSFTESSSKESQNTAEIISPPSPDRP------PHSQ 2129
P +T +E+ T SP T F SS+ + I SPD HS
Sbjct: 637 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 696
Query: 2130 TSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLS-SGLR 2188
TSG S RI +P + PG P + T + LS + +
Sbjct: 697 TSGRGE----STTSRI-SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 751
Query: 2189 SIGSRRHSTSSLSPQRSKLRIMSPMRTGN---------TYSRNNVSSVSTT---GTATDL 2236
S+G ST+S S S +SP T YS + S+ +T T T +
Sbjct: 752 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSV 811
Query: 2237 ESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDL 2296
H P ++ T+L ST+S L +++ GS +S A+
Sbjct: 812 HGEEPTTFHSR-PASTHTTLFTEDSTTSGLTE-------ESTAFPGSPASTQTGLPAT-- 861
Query: 2297 VSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS 2356
++ L E T SS S G+ KL+P +TTS + S PS
Sbjct: 862 -LTTADLGEESTTFPSSSGSTGT----------KLSP-ARSTTSGLVGEST------PSR 903
Query: 2357 VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINE 2416
+S SS E + P +++ + + ++ SPD T SG+S SS +
Sbjct: 904 LSPSSTETTTLPGSPTTPSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 960
Query: 2417 HMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQ 2476
GS+ F + ++ + + +G+ + T +GQ
Sbjct: 961 QPGSTH-----------TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 1009
Query: 2477 RPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKR---TVKVTLTPLK----- 2528
+ SS GD ++ P + E P ++ TLTP
Sbjct: 1010 QSTTFHSSP--GDTETTL-----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062
Query: 2529 MENESQSKNALKESSPASPLQIESTSPTEPISAS--ENPGDGPVAQPSPNNTSC-QDSQS 2585
++ ES + + SS +P +T+ +S + P P S ++T+ + +S
Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122
Query: 2586 NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDI 2645
+ P + P P S + G T G+ E+
Sbjct: 1123 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL---SEKST 1179
Query: 2646 PFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFT----RTVISSGGEERLASHN 2701
FYSS A G + ST+ + T T + +E ASH+
Sbjct: 1180 TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHS 1239
Query: 2702 LFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDA 2761
+ P + + G ES T ++ + + N +G
Sbjct: 1240 SPGSTDTTLSPGSTTASSL--GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST 1297
Query: 2762 GEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLL 2821
G H T S G + + +D++ A ++ +S V ST S +
Sbjct: 1298 G-SPHTTLSPAGSTTR---QGESTTFQSWPSSKDTMPAPPTT--TSAFVELSTTSHGSPS 1351
Query: 2822 DTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGL 2881
T T S + S++ + ++P A SP S++ L + E
Sbjct: 1352 STPTTHFSASSTTLGRSEESTTV----------HSSPVATATTPSPARSTTSGL-VEEST 1400
Query: 2882 GLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTV 2941
S+ + F + + + S +S S P PS S L PT
Sbjct: 1401 AYHSSPGSTQTMH--FPESSTASGRSEESRTSHSSTTHTISSP---PSTTSAL-VEEPTS 1454
Query: 2942 PSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDA 3001
+P +A + + +S S P + G+ P P T +
Sbjct: 1455 YHSSPGSIATTHFPESSTTSGRSEESTASHSSPD--TNGITPLPAHFTTSGRIAE---ST 1509
Query: 3002 DHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVP-----VSPTVPIQNQKYVPNS----TD 3052
SP GS+E L ++TPGL S V Y+ S T
Sbjct: 1510 TFYISP--GSME------TTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTL 1561
Query: 3053 SPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPL 3088
P S S ++T H P+ IV ++++ L
Sbjct: 1562 FPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETL 1597
Score = 44.3 bits (103), Expect = 0.002
Identities = 115/556 (20%), Positives = 191/556 (34%), Gaps = 61/556 (10%)
Query: 445 STPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERS 504
ST +++ S PS ++AA H+S SS S ++ D+ST S SEE + S
Sbjct: 22 STTHTKSSTPS------TTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA--SHSS 73
Query: 505 DTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTS--SSPP 562
LP +P D S +S S + +T ++ T+ SSP
Sbjct: 74 PDAMATTVLPAGSTPSVLVGD--STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR 131
Query: 563 PPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSL 622
P T P +S +S+ + + P ST M G + ++
Sbjct: 132 SPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTT-MPGLSQE---------STA 181
Query: 623 KHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPL 682
HS P + + + P + F P + E +ASG ++ P+
Sbjct: 182 SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEAS---MPV 238
Query: 683 HSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFS 742
HS T RSP +P+ + +R ES T S +S T + + +
Sbjct: 239 HSST------RSP---HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTT--------T 281
Query: 743 PIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHS 802
EP + SH G SS + ++ S+ S + S + ++ T FP S
Sbjct: 282 SAFVEPSTTSH------GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFP-ES 334
Query: 803 LTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDR 862
T SG E T SS+P+ T + E + +P +
Sbjct: 335 DTTSGRGEESTTSHSSTTHT-----ISSAPS------TTSALVEEPTSYHSSPGSTATTH 383
Query: 863 DADKSVEKDKSRERDREREKENKRES-RKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDV 921
D S +S E ++ + R S + S P+ S E
Sbjct: 384 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 443
Query: 922 ATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAP 981
T+ + + SS T ++ + + + + G+ T T P
Sbjct: 444 TTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP 503
Query: 982 SLEKEKTLCLSTPSSS 997
L + T S+P S+
Sbjct: 504 GLSRHSTTSHSSPGST 519
Score = 40.4 bits (93), Expect = 0.035
Identities = 110/512 (21%), Positives = 180/512 (35%), Gaps = 86/512 (16%)
Query: 3163 HSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRP 3222
HS P A ++ P S P +L+G P +S S T A P S K
Sbjct: 71 HSSPDAMATTVLPAGSTP--SVLVGDSTPSP----ISSGSMET-----TALPGSTTKPGL 119
Query: 3223 ISRLQTRKNKKLAPSST--PSNIAPSDVVSNMTLINFTPSQ-----LPNHPSLLDLGSLN 3275
+ T + +P +T P+++ S V T + P P ++ L +
Sbjct: 120 SEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQES 179
Query: 3276 TSSHRTV--------PNIIKRSKSSIMY--FEPAP------LLPQSVGGTAATAAG---- 3315
T+SH + P S Y F P LLP + + A
Sbjct: 180 TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 239
Query: 3316 TSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTT--TTPTSSASVPGHVTLTNPRLLGTP 3373
+ST S T+ +GS + S++ + S + T PT++++ T ++ G+P
Sbjct: 240 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH----GSP 295
Query: 3374 DIGSISNLLIKASQQSLGIQDQPVALPPSSGM-----FPQLGTSQTPSTAAITAASS--- 3425
SI I A + G+ ++ S G FP+ T+ + T+ SS
Sbjct: 296 S--SIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH 353
Query: 3426 -ICVLPSTQTTGITA-----ASPSGEADEHYQLQHVNQLLASK-TGIHSSQRDLDSASGP 3478
I PST + + +SP A H+ + + T HSSQ + P
Sbjct: 354 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 413
Query: 3479 QVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKP 3538
S + + + + ++A+ S T+PG S S + +SP P T
Sbjct: 414 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF---HSSPRSPATTLSPA 470
Query: 3539 KTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQ 3598
T G ++ S R S+ TT+ T TPG + S
Sbjct: 471 ST------TSSGVSEESTTSRSRPGST-------HTTAFPDSTTTPGLSRHSTTSHSSPG 517
Query: 3599 SSQKECGQPAGQVAVLPEVQVTQNPANEQESA 3630
S+ +LP T P+ E ++
Sbjct: 518 ST---------DTTLLPASTTTSGPSQESTTS 540
Score = 39.3 bits (90), Expect = 0.079
Identities = 99/434 (22%), Positives = 149/434 (34%), Gaps = 66/434 (15%)
Query: 441 ARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSS---RSSSPSV-----DTSTDSQA 492
+R STP + FSA S + + HSS ++ ++ S+ SV TS S
Sbjct: 1099 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 1158
Query: 493 SEEIQVLP--------EERSDTPEVHPPLP-ISQSPENESNDRRSRRYSVSERSFGSRTT 543
S E LP E+S T P P + SP + ++ S + S GS T
Sbjct: 1159 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1218
Query: 544 KKL---STLQSAPQQQTSSSPPP--------PLLTPPPPLQPASSISDHTPWLMPPTI-- 590
+T+ Q+ T+S P P T L P S+ +P T+
Sbjct: 1219 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP 1278
Query: 591 --PLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIF 648
AS L AST P T H+ P ++ + P
Sbjct: 1279 DNTTASGLLEAST-------------PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSS 1325
Query: 649 DNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAH 708
+ P P T ++ G+ +S S T + S + H
Sbjct: 1326 KDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES----------TTVH 1375
Query: 709 SRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELS 768
S + T PS S + S + P S + S R+ R S S +
Sbjct: 1376 SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 1435
Query: 769 PL--TPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEP 826
+PPS+ S+ + S ++ T FP S T SG S E T++ + P
Sbjct: 1436 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESS-TTSGRSEE-------STASHSSP 1487
Query: 827 FSSSSPTPLFPWFT 840
++ TPL FT
Sbjct: 1488 -DTNGITPLPAHFT 1500
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 84.7 bits (208), Expect = 2e-15
Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 2/137 (1%)
Query: 3833 VYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR-EKYYDSKGIGCYMFRIDDSE 3891
+ ++ G GL KR+I GE V EY G +I + R ++ +++ YM +
Sbjct: 1149 IIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDR 1208
Query: 3892 VVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDA 3951
++DA GN +RF+NHSC PNC ++ ++G + +FA+ I G ELT++Y
Sbjct: 1209 IIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCL-G 1267
Query: 3952 SNKLPCNCGAKKCRKFL 3968
+ + C+CGA C FL
Sbjct: 1268 NGRTECHCGADNCSGFL 1284
Score = 37.0 bits (84), Expect = 0.39
Identities = 40/147 (27%), Positives = 60/147 (40%), Gaps = 9/147 (6%)
Query: 763 SSSELSPLTP--PSSVS----SSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRP 816
++ +L PLT PSS+S + S + + N + S T S N RP
Sbjct: 62 TTEDLPPLTNGYPSSISVYETQTKYQSYNQYPNGSANGFGAVRNFSPTDYYHSEIPNTRP 121
Query: 817 RKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDA-DKSVEKDKSRE 875
+ P+ P P P P +T K K + + R+ + S+ D E
Sbjct: 122 HEILEKPSPP--QPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNE 179
Query: 876 RDREREKENKRESRKEKRKKGSEIQSS 902
++K ESRKEKRKK ++ SS
Sbjct: 180 VQASEHTKSKHESRKEKRKKSNKHDSS 206
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 83.6 bits (205), Expect = 4e-15
Identities = 322/1580 (20%), Positives = 535/1580 (33%), Gaps = 217/1580 (13%)
Query: 2086 TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRI 2145
T + T+ H TS S T + SP + TS C S +
Sbjct: 205 TTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSG--ETATSSLCSVTNTSMMTSE 262
Query: 2146 R---TPSYSPTQRSPG-CRPLPSAGSPTPTTHEIVTVGDP---------LLSSGLRSIGS 2192
+ T S T +PG +P GS P T + DP S+ + S
Sbjct: 263 KITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFS 322
Query: 2193 RRHSTSSLSPQR----SKLRIMSPMRTGNTYSRNN-------------VSSVSTTGTATD 2235
+ H T S+ R + L ++P+ T S + S +TT + +
Sbjct: 323 KNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSS 382
Query: 2236 LESSAKVVDHVLG-PLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSS--SSEMKQSS 2292
+ ++ V V P + ++LG TS ++ T+ + +K S + S S+ + SS
Sbjct: 383 VSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSS 442
Query: 2293 ASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFA 2352
+S + + + + + E S+ + PG+ + +H TT+ SF+
Sbjct: 443 LPPKISTAFHTQQSEGAETTGRPHERSSFS---PGVSQEIFTLHETTTWP------SSFS 493
Query: 2353 EPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSG----MS 2408
++S E S G ST +A + P ++V + G S
Sbjct: 494 SKGHTTWSQTELPSTS----TGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYS 549
Query: 2409 NRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEF---- 2464
+ S+ + + G+ ++ + + + E SS S+ + T + P
Sbjct: 550 SHSTTLPKTTGAGAQTQWTQETGTTGEALL---SSPSYSVTQMIKTATSPSSSPMLDRHT 606
Query: 2465 MDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTL 2524
++ T ++ S+ +S G +AP E +P T VT
Sbjct: 607 SQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTT 666
Query: 2525 --TPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQD 2582
+ S S+ +++ S + +PT ++ P A PS ++ +
Sbjct: 667 PGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGP 726
Query: 2583 SQSNNYQN---LPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRS 2639
S + L + + + P GP+ Q + P +A T G
Sbjct: 727 SGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQ 786
Query: 2640 YGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLAS 2699
E +SS + +A GA + S + IS+ GE S
Sbjct: 787 TSEP-----ASSGSRTTSAGTATPSSSGASGTTPSGSEG----------ISTSGETTRFS 831
Query: 2700 HNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPE 2759
N R+ T+S T + + + IP G +
Sbjct: 832 SNPSRDSHT---------------TQSTTELLSASASHGAIPVSTGMASSI--------- 867
Query: 2760 DAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKN 2819
H T S P + S A +S + ++R TS SD
Sbjct: 868 -VPGTFHPTLSEASTAGRPTGQS----SPTSPSASPQETAAISRMAQTQRTRTSRGSDTI 922
Query: 2820 LLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALG-ESPESSSSELLNLG 2878
L + T D V PS+ + G SP++ + L G
Sbjct: 923 SLASQAT---------------------DTFSTVPPTPPSITSTGLTSPQTETHTLSPSG 961
Query: 2879 EGLGLDS---NREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSV-L 2934
G + + + + S T P+ + +SS+S LP+ PS +S
Sbjct: 962 SGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGH 1021
Query: 2935 TTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHF 2994
TT P + + S V + +T S AS+ L GH+TP
Sbjct: 1022 TTPLPVTDTSSESTGHVTP------LPVTSFSSASTGDSTPLPVTDTSSASTGHVTP--- 1072
Query: 2995 IQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP 3054
+ S G +T SS + ++P+ + V +P
Sbjct: 1073 ---------LPVTSLSSASTGDTTPLPVTDTSSA---STGHATSLPVTDTSSVSTGHTTP 1120
Query: 3055 GPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSV 3114
P +++A T P T+ V + PL+V Q L V+S SV
Sbjct: 1121 LPVTDTSSA-STGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPL--PVTSLSSV 1177
Query: 3115 METNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFP 3174
+T+ L T P L T S + LP++ + + A +S P
Sbjct: 1178 STGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHA---TSLP 1234
Query: 3175 PNISNPPSGLLIG-VQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKK 3233
I PS G P P + + Q T L T + S P+ T
Sbjct: 1235 VTI---PSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTST----- 1286
Query: 3234 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSI 3293
S++ ++ P V S S H + L + SL+++S + S SS
Sbjct: 1287 --SSASTGHVTPLHVTS-------PSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA 1337
Query: 3294 MYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTT--- 3350
+ P LP + + +T T D S ++G + L +S L+ VS TT
Sbjct: 1338 STGDTTP-LPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTS--LSSVSTGDTTPLP 1394
Query: 3351 -TPTSSASVPGHVTLTNPRLLGTPDIGSISNLLI--KASQQSLGIQDQPVALP--PSSGM 3405
T SSAS GH T + G + L + +S + PV +P S+G
Sbjct: 1395 VTSPSSAST-GHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGH 1453
Query: 3406 FPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASP----SGEADEHYQLQHVNQLLAS 3461
L + T S + A S + S+ +TG T P S + H HV ++
Sbjct: 1454 TTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSA 1513
Query: 3462 KTGIHSSQRDLDSASGPQVSN-FTQTVDAPNSMGLEQNKAL----SSAVQASPTS--PGG 3514
TG H++ + S S + V +P+S L +S+V T+ P
Sbjct: 1514 STG-HATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVT 1572
Query: 3515 SPSSPSSGQRSASP------SVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE-- 3566
SPSS S+G + P + G T P P T P G + TSS+
Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPVTS----PSSASTGHTTPLPVTDTSSASTG 1628
Query: 3567 --AHIPDQETTSLTSGTGTP 3584
+P +SL++G TP
Sbjct: 1629 DTTPLPVTNASSLSTGHATP 1648
Score = 65.1 bits (157), Expect = 1e-09
Identities = 175/801 (21%), Positives = 292/801 (36%), Gaps = 92/801 (11%)
Query: 2837 NSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSE----LLNLGEGLGLDSNREKDMG 2892
+S G+ P + D +T +L + SS+S L + + + + +
Sbjct: 1815 SSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLL 1874
Query: 2893 LFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVI 2952
+ + S T P+ + ++S S + PL + SV T + ++P + L+
Sbjct: 1875 VTDASSVSTGDTTPLPVTDTNSASTGDT--TPLHVTDASSVSTGHATSLPVTS---LSSA 1929
Query: 2953 SDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTP------DHFIQGHMDADHISS 3006
S + +T S ASS L P GH T GH A +
Sbjct: 1930 STGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGH--ATPLPV 1987
Query: 3007 PPCGSVEQGHGNNQDLTRNSS-TPGLQVPVSPT------------VPIQNQKYVPNSTDS 3053
SV GH +T SS + G P+ T +P+ + D+
Sbjct: 1988 TDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDT 2047
Query: 3054 PGP-SQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTP 3112
P P + +S+ + T P P T + PL V TS + +
Sbjct: 2048 PLPVTSLSSVSTGDTTP--LPVTSPSSASTGHATPLLVTDA---SSVSTGHATSLLVTDA 2102
Query: 3113 SVMETNTSVLGPMGGGLTLTTGLNPSLP-TSQSLFPSASKGLLPMSHHQ-----HLHSFP 3166
S + T + + +L+TG LP TS S + LP++ H S P
Sbjct: 2103 SSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLP 2162
Query: 3167 AATQSSFPPN------ISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKK 3220
SS +++ S P P + + Q T L T +PSS
Sbjct: 2163 VTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVT--SPSSASTG 2220
Query: 3221 RPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR 3280
I L T + +TP P +S+ + + TP LP + D S++T
Sbjct: 2221 HAIPLLVTDTSSASTGQATP---LPVTSLSSASTGDTTP--LP----VTDASSVSTGHAT 2271
Query: 3281 TVPNIIKRSKSSIMYFEPAPL---LPQSVG-GTAATAAGTSTISQDTSHLTSGSVSGLAS 3336
++P S SS+ + PL P S G A T S T H T V+ L+S
Sbjct: 2272 SLP---VTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSS 2328
Query: 3337 SSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQP 3396
+S+ + T+P+S+++ GH T + + G + L + +S + P
Sbjct: 2329 AST--GDTTPLPVTSPSSAST--GHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTP 2384
Query: 3397 VALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVN 3456
LP + G + TP T+++S TG+++AS +G+ V
Sbjct: 2385 --LPVTDASSASTGDT-TPLPVTDTSSASTGHATHLPVTGLSSAS-TGDTTR----LPVT 2436
Query: 3457 QLLASKTGIHSSQRDLDSASG-------PQVSNFTQTVDAPNSMGLEQNKALSSAVQASP 3509
+ ++ TG H++ + S S P T +V ++ L A S + +
Sbjct: 2437 NVSSASTG-HATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTT 2495
Query: 3510 TSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEA-- 3567
P SPSS S+G + P P+ T + +H S TS S A
Sbjct: 2496 RLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSAST 2555
Query: 3568 ----HIPDQETTSLTSGTGTP 3584
+P +T++ ++G TP
Sbjct: 2556 GHATSLPVTDTSAASTGHATP 2576
Score = 59.7 bits (143), Expect = 6e-08
Identities = 159/719 (22%), Positives = 247/719 (34%), Gaps = 66/719 (9%)
Query: 2904 TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTIT 2963
T P+ + +SS S LP+ S S T + +P + S S + +T
Sbjct: 2814 TTPLPVTDTSSASTGHATSLPVTDTSSAS--TGHATPLPDTDTSSA---STGHATLLPVT 2868
Query: 2964 EKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSP----PCGSVEQGHGNN 3019
+ S AS +L GH TP H + ++P S GH N
Sbjct: 2869 DTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANP 2928
Query: 3020 QDLTRNSSTP---GLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATE 3076
+T SS +PV+ T + ++T P S S + TTP P T
Sbjct: 2929 LHVTSPSSASTGHATPLPVTDT----SSASTGHATPLPVTSLSSVSTGDTTP---LPVTS 2981
Query: 3077 KLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLN 3136
+ PL V T Q L V+ST S +T+ L P+ + +TG
Sbjct: 2982 PSSASTGHTTPLPVTDTSSASTGQATALP--VTSTSSASTGDTTPL-PVTDTSSASTGQA 3038
Query: 3137 PSLP-TSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQ 3195
LP TS S + LP++ A+T + P +++ S P P
Sbjct: 3039 TPLPVTSLSSVSTGDTTPLPVTSPSS-----ASTGHATPLLVTDASSASTGQATPLPVTS 3093
Query: 3196 LLVSESSQRTDLSTTVATPSS-----GLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVS 3250
L + T L T + +S L S T L P + S+ D S
Sbjct: 3094 LSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSL-PVTDTSSAYTGDTTS 3152
Query: 3251 NMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTA 3310
+ S P L+ S ++ H T + S +S + P + S T
Sbjct: 3153 LPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTG 3212
Query: 3311 ATAAG--TSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPR 3368
T T T S T H T V+GL+S+S + TT P + S T
Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSAS------TGDTTRLPVTDISSASTGQATPLP 3266
Query: 3369 LLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASS--- 3425
+ T + + + + + S LP +S G + TP T+++S
Sbjct: 3267 VTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHA-TPVPVTSTSSASTGH 3325
Query: 3426 ICVLPST--------QTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASG 3477
LP T TT + SPS + H HV ++ TG S+ ++S
Sbjct: 3326 TTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSA 3385
Query: 3478 ------PQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSV- 3530
P T +V ++ L S + + P SS S+GQ + P
Sbjct: 3386 STGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTS 3445
Query: 3531 -----PGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTP 3584
G T P T + + ++ +P +T+S ++G TP
Sbjct: 3446 LSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATP 3504
Score = 57.8 bits (138), Expect = 2e-07
Identities = 195/941 (20%), Positives = 314/941 (33%), Gaps = 129/941 (13%)
Query: 2766 HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYN 2825
HVT +S + S+S V T L S S+ +D + T +
Sbjct: 1154 HVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGH 1213
Query: 2826 TELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDS 2885
L ++ S D LP I PS + G + ++ + G
Sbjct: 1214 ATPLPVTDASSVSTDHATSLPVTI--------PSAASTGHTTPLPVTDTSSASTG----- 1260
Query: 2886 NREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQN 2945
+ L + + T + V+S+ SA PL + S S T + +P +
Sbjct: 1261 ---QATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS 1317
Query: 2946 PSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHIS 3005
L+ S + +T S AS+ L GH TP H + +
Sbjct: 1318 ---LSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQA 1374
Query: 3006 SP----PCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISN 3061
+P SV G +T SS P+ ST P +++
Sbjct: 1375 TPLPVTSLSSVSTGDTTPLPVTSPSSAS-----TGHATPLLVTDTSSASTGHATPLPVTD 1429
Query: 3062 AA-VQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTS 3120
A+ V T P T + PL V T Q L V+ T SV +T+
Sbjct: 1430 ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLL--VTDTSSVSTGDTT 1487
Query: 3121 VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP 3180
L T + P TS S + LP++ A+T + P +++P
Sbjct: 1488 PLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSS-----ASTGDTMPLPVTSP 1542
Query: 3181 PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP 3240
S P P + T L T + +S P+ T K + P
Sbjct: 1543 SSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLP 1602
Query: 3241 SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSS----HRTVPNIIKRSKSSIMYF 3296
S + T + T + + L N SS H T ++ S +S +
Sbjct: 1603 VTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHA 1662
Query: 3297 EPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSS----------VLNVVSM 3346
P P+ TST S T H T V+GL+S+++ V + +
Sbjct: 1663 TPLPV--------------TSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTG 1708
Query: 3347 QTTTTPTSSAS--VPGHVT---LTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPP 3401
Q T P +S S G T +T+P T G S LL+ + + Q P+ +
Sbjct: 1709 QATPLPVTSLSSVSTGDTTPLPVTSPSSAST---GHASPLLVTDASSASTGQATPLPVTD 1765
Query: 3402 SSGM-------FPQLG--------TSQTPSTAAITAASSICV-----LPSTQTTG----- 3436
+S + P G T++ P T +A++ + PS+ +TG
Sbjct: 1766 TSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPL 1825
Query: 3437 -ITAAS--------------PSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSAS----- 3476
+T AS PS + H V + TG +S D++S
Sbjct: 1826 PVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGD 1885
Query: 3477 -GPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ------RSASPS 3529
P T + ++ L A S + + + P S SS S+G S S +
Sbjct: 1886 TTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSA 1945
Query: 3530 VPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAE 3589
G T P P T +P + ++ +P + +S+++G TP
Sbjct: 1946 SSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP---LP 2002
Query: 3590 QQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESA 3630
DT+SV S+ + P ++ T P + SA
Sbjct: 2003 VTDTSSV--STGQATPLPVTSLSSASTGDTTPLPVTDTSSA 2041
Score = 57.8 bits (138), Expect = 2e-07
Identities = 171/789 (21%), Positives = 278/789 (35%), Gaps = 140/789 (17%)
Query: 2895 EVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLS--------VLTTRSPTVPSQNP 2946
++ S P+ + +SS+S + LP+ PS S V +T S + P
Sbjct: 3253 DISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATP 3312
Query: 2947 SRLAVISDSGEKRVT---ITEKSVASSESDPALLSPGVDPTPEGHMTPDHF-IQGHMDAD 3002
+ S + T +T+ S AS+ L GH TP H I
Sbjct: 3313 VPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTG 3372
Query: 3003 HISSPP---CGSVEQGHGNNQDLTRNSS-TPGLQVPVSPT------------VPIQNQKY 3046
S+ P S GH +T SS + G P+ T +P+ +
Sbjct: 3373 DTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASS 3432
Query: 3047 VPNSTDSPGP-SQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQT--LPNGVTQKIQ 3103
+P P + +S+ + T P L T+ V + PL V T G T ++
Sbjct: 3433 ASTGQATPLPVTSLSSVSTGDTTPLL--VTDASSVSTGHATPLPVTDTSSASTGDTTRLP 3490
Query: 3104 LT------------------SSVSS---TPSVMETNTSVLG------PMGGGLTLTTGLN 3136
+T SSVS+ TP ++ +SV P+ + +TG
Sbjct: 3491 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDT 3550
Query: 3137 PSLPTSQSLFPSASKGL-LPM-----SHHQHLHSFPAATQSSF------PPNISNPPSGL 3184
LP + + S + LP+ S H P + SS P ++++P S
Sbjct: 3551 TRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSAS 3610
Query: 3185 LIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA 3244
V P P + + T L T A+ S P+ A S++ +
Sbjct: 3611 TGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTD-------ASSASTGDTT 3663
Query: 3245 PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPL-LP 3303
P V + + LP + L S++T +P + S +S + P P+ +P
Sbjct: 3664 PLPVTDTSSASTGQATPLP----VTSLSSVSTGDTTPLP-VTDASSASTGHATPLPVTIP 3718
Query: 3304 QSVG-GTAATAAGTSTISQDTSHLTSGSVSGLASSSS-------VLNVVSMQT------T 3349
SV G TS S T H T V+GL+S+S+ V + S T
Sbjct: 3719 SSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLP 3778
Query: 3350 TTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQL 3409
T TSSAS L + + G + L + ++ + P+ + +S +
Sbjct: 3779 VTDTSSASTDDTTRLPVTD-VSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGH 3837
Query: 3410 GTSQTPSTAAITAASSICVLPSTQTTGIT--------AASPSGEADEHYQLQHVNQLLAS 3461
TS ++ + + LP T T+ ++ S S + H V ++
Sbjct: 3838 ATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSA 3897
Query: 3462 KTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSS 3521
TG H++ + S S + T + N+ L A V SPSS S
Sbjct: 3898 STG-HATPVPVTSTSSASTGD-TTPLPVTNASSLSTGHATPLHVT--------SPSSASR 3947
Query: 3522 GQRS------ASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETT 3575
G S AS + G P P T +S + T + +P +T+
Sbjct: 3948 GDTSTLPVTDASSASTGHATPLPLT---------------SLSSVSTGDT-TPLPVTDTS 3991
Query: 3576 SLTSGTGTP 3584
S ++G TP
Sbjct: 3992 SASTGQATP 4000
Score = 53.9 bits (128), Expect = 3e-06
Identities = 189/952 (19%), Positives = 319/952 (33%), Gaps = 173/952 (18%)
Query: 2796 SLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELL-KSDSDNNNSDDCGNILPSDIMDFVL 2854
+LE Q S+ SSR + + T +TE K+ +D + S + V+
Sbjct: 53 TLEGQ-STAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSPSVHNVM 111
Query: 2855 KNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQ-LPTTEPVDSSVSS 2913
+ P + P S ++ L+ + + + ++ + +G E S ++ PV S+VS
Sbjct: 112 ETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSI 171
Query: 2914 SISAEEQFELP----------------------LELPSDLSVLTTRSPTVPSQNPSRLAV 2951
+ E Q S S LT R+ + PS +PS V
Sbjct: 172 TAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNV 231
Query: 2952 I-------SDSGEKRVT----ITEKSVASSESDPALLSPG------------------VD 2982
S SGE + +T S+ +SE S G +
Sbjct: 232 TGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMP 291
Query: 2983 PTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGN--------NQDLTRNSSTPGLQVP 3034
T +T D Q S+ + + H +Q T N+ TP
Sbjct: 292 VTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTST 351
Query: 3035 V-------SPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQP 3087
V +P+ + + + T + PS +SN + T+ P + + N
Sbjct: 352 VLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETS 411
Query: 3088 LYVLQTLPNGVTQKIQL-----TSSVSSTPSVM--ETNTSVLGPMGGGLTLT------TG 3134
L V T+ + +T K+ T S + +PS + + +T+ G T +
Sbjct: 412 LSVSGTI-SAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSS 470
Query: 3135 LNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNIS---------NPPSGLL 3185
+P + SQ +F P S H+ +Q+ P + NP +G
Sbjct: 471 FSPGV--SQEIFTLHETTTWPSSFSSKGHT--TWSQTELPSTSTGAATRLVTGNPSTGTA 526
Query: 3186 IGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP 3245
+ P + E + TT ++ S+ L K + QT+ ++ + +P
Sbjct: 527 GTIPRVPSKVSAIGEPGE----PTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSP 582
Query: 3246 SDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQS 3305
S V+ M +PS P L+ + + + + S+I +P +
Sbjct: 583 SYSVTQMIKTATSPSSSP---------MLDRHTSQQITTAPSTNHSTIHSTSTSPQESPA 633
Query: 3306 VGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLT 3365
V T A +T T+ SV + +T TTP SS + GH
Sbjct: 634 VSQRGHTQAPQTTQESQTTR-------------SVSPMTDTKTVTTPGSSFTASGH---- 676
Query: 3366 NPRLLGTPDIGSISNLLIKA----------SQQSLGIQDQPVALPPSSGMFPQLGTSQTP 3415
+P + D +IS A + +Q P + + G P GTS +
Sbjct: 677 SPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLG--PSGGTSLS- 733
Query: 3416 STAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSA 3475
T A+T A+S+ P T+AS S D + H +Q A
Sbjct: 734 KTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQ-----------------A 776
Query: 3476 SGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTK 3535
+ S TQT + +S S T+ G+ + SSG +PS
Sbjct: 777 ESTEASGQTQTSEPASS--------------GSRTTSAGTATPSSSGASGTTPSGSEGIS 822
Query: 3536 PKPKTKRFQL-PLDKGNGKKHKVSHLRTSSSEAHIPDQE--TTSLTSGTGTPGAEAEQQD 3592
+T RF P + + L S+S IP +S+ GT P
Sbjct: 823 TSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTA 882
Query: 3593 TASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSS 3644
QSS + A + + TQ + S + FS+
Sbjct: 883 GRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFST 934
Score = 47.4 bits (111), Expect = 3e-04
Identities = 156/703 (22%), Positives = 244/703 (34%), Gaps = 106/703 (15%)
Query: 2900 QLPTTEPVDSSVSSSISAEEQFELPLELPSD--------LSVLTTRSPTVPSQNPSRLAV 2951
+LP T+ +SS S + LP+ +PS L V +T S + P +
Sbjct: 3552 RLPVTD------TSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTS 3605
Query: 2952 ISDSGEKRVT---ITEKSVASSESDPALLSPGVDPTPEGHMTP----DHFIQGHMDADHI 3004
S + VT +T S AS+ LL GH TP D D +
Sbjct: 3606 PSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPL 3665
Query: 3005 SSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQIS-NAA 3063
S G +T SS V T P+ ST P ++ ++
Sbjct: 3666 PVTDTSSASTGQATPLPVTSLSS-----VSTGDTTPLPVTDASSASTGHATPLPVTIPSS 3720
Query: 3064 VQTTPPHLKPATEKLIVVNQNMQPLYV--LQTLPNGVTQKIQLTSSVSS-----TP---- 3112
V T P T + PL V L + G T + +T + S+ TP
Sbjct: 3721 VSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVT 3780
Query: 3113 --SVMETNTSVLGPMGGGLTLTTGLNPSLP-TSQSLFPSASKGLLPMSHHQ-----HLHS 3164
S T+ + P+ + +TG LP TS S + LP++ H S
Sbjct: 3781 DTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATS 3840
Query: 3165 FPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPIS 3224
P ++SS + P L V+++S +ST ATP +S
Sbjct: 3841 LPVTSRSSASTGHATP---------------LPVTDTSS---VSTGHATPLPVTSTSSVS 3882
Query: 3225 RLQTRKNKKLAPSSTPSNIA-PSDVVSNMTLINFTPSQLP-NHPSLLDLGSLNTSSHRTV 3282
+PSS + A P V S + + LP + S L G T H T
Sbjct: 3883 TGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHA-TPLHVTS 3941
Query: 3283 PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHL----TSGSVSGLASSS 3338
P+ R +S + A + +S + DT+ L TS + +G A+
Sbjct: 3942 PSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL 4001
Query: 3339 SVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVA 3398
V ++ S+ T T ++P + + L D S+S
Sbjct: 4002 PVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVST-------------GHGTP 4048
Query: 3399 LPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQL 3458
LP +S G + TP T+++S + T + S + H V L
Sbjct: 4049 LPVTSTSSASTGDT-TPLPVTDTSSAS-----TGHATPLPVTDTSSASTGHATPLPVTSL 4102
Query: 3459 LASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSM---GLEQNKALSSAVQASPTSPGGS 3515
+ TG H++ + SA+ S T + D+P M G+ + + + TSP +
Sbjct: 4103 SSVSTG-HATPLAVSSAT----SASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPT 4157
Query: 3516 PSS------PSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNG 3552
S PS+ + S + P P P+ F P G G
Sbjct: 4158 TSQTIISTIPSTAMHTRSTAAPIPILPERGVSLF--PYGAGAG 4198
Score = 37.7 bits (86), Expect = 0.23
Identities = 85/406 (20%), Positives = 147/406 (36%), Gaps = 69/406 (16%)
Query: 447 PNSRFSAPSCGSS------EKSSAASQHSS-----QMSSDSSRSSSPSVDTSTDSQASEE 495
P + FS+ S G S + SSA++ H + +SS S+ ++P T T S ++
Sbjct: 1042 PVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGH 1101
Query: 496 IQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQ 555
LP + + P+ + + ++ + V++ T +ST + P
Sbjct: 1102 ATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTD-------TSSVSTGHTTPLH 1154
Query: 556 QTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPL------ASPFLPASTAPMQGKRK 609
T +S P P+ SS+S +P T P A+P L T+
Sbjct: 1155 VTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHA 1214
Query: 610 SILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSA 669
+ L S H+ S P SA A G + P P+T SA
Sbjct: 1215 TPLPVTDASSVSTDHATSLPVTIPSA--ASTG--------HTTPLPVTDTS-------SA 1257
Query: 670 SGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSS 729
S A++ L + S + D +PL + S H P + TS ++S+
Sbjct: 1258 STGQATSLLVTDTSSVSTGD---TTPLPVTSTSSASTGH-------VTPLHVTSPSSAST 1307
Query: 730 GVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLAT 789
G + +P S + P+T PSS S+ + +
Sbjct: 1308 GHA-----------------TPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDA 1350
Query: 790 SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPL 835
S+++ T P H +T + ++ P TS + ++P P+
Sbjct: 1351 SSVSTGHTTPLH-VTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 1395
Score = 35.4 bits (80), Expect = 1.1
Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 14/151 (9%)
Query: 453 APSCGSSEKSSAASQHSSQM-----SSDSSRSSSPSVDTSTDSQASEEIQVLP--EERSD 505
A S + SSA++ H++ + S+ S+ ++P TST S ++ + LP + S
Sbjct: 2542 ATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSA 2601
Query: 506 TPEVHPPLPISQSPENESNDRRSRRYS-VSERSFGSRT------TKKLSTLQSAPQQQTS 558
+ PLP++ + + D + S S G T T +ST + P TS
Sbjct: 2602 STGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTS 2661
Query: 559 SSPPPPLLTPPPPLQPASSISDHTPWLMPPT 589
S T P P+ ASS+S +P T
Sbjct: 2662 PSSASTGHTTPLPVTDASSVSTGHATSLPVT 2692
Score = 33.5 bits (75), Expect = 4.3
Identities = 89/400 (22%), Positives = 150/400 (37%), Gaps = 61/400 (15%)
Query: 462 SSAASQHSS-----QMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPIS 516
SSA++ H++ +SS S+ + P TS S ++ + LP + + P+
Sbjct: 1303 SSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLH 1362
Query: 517 QSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTP-------- 568
+ + ++ ++ V+ S S +T + L S+ PLL
Sbjct: 1363 VTDASSASTGQATPLPVT--SLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1420
Query: 569 ---PPPLQPASSISDHTPWLMPPTIPLAS--------PFLPASTAPMQGKRKSILREPTF 617
P P+ ASS+S +P TIP A+ P S+A G+ S+L T
Sbjct: 1421 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSA-STGQATSLLVTDT- 1478
Query: 618 RWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASAR 677
+S+ + P +S A G + TP V S SAS A+
Sbjct: 1479 --SSVSTGDTTPLPVTSTSSASTGHV-------------TPLHV--TSPSSASTGHATPL 1521
Query: 678 LFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRK 737
+ L S + D + P +PS A + T P T A + S+G
Sbjct: 1522 PVTSLSSASTGD------TMPLPVTSPSSAST----GDTTPLPVTDASSVSTG---HTTP 1568
Query: 738 RKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPL--TPPSSVSSSLSISVSPLATSALNPT 795
V SP + + T + S + +PL T PSS S+ + + TS+ +
Sbjct: 1569 LPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTG 1628
Query: 796 FTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPL 835
T P +T + + + P TS + ++P P+
Sbjct: 1629 DTTPL-PVTNASSLSTGHATPLHVTSPSSASTGHATPLPV 1667
Score = 33.5 bits (75), Expect = 4.3
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 11/121 (9%)
Query: 473 SSDSSRSSSPSVDTSTDSQASEEIQVLP-EERSDTPEVHP-PLPISQSPENESNDRRSRR 530
SS S+ +SP + T S ++ + LP + S H PLP++ ++D + R
Sbjct: 1735 SSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDD--TTR 1792
Query: 531 YSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTI 590
V++ S ST Q+ P TS S T P P+ ASS S +P TI
Sbjct: 1793 LPVTDVS-------SASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTI 1845
Query: 591 P 591
P
Sbjct: 1846 P 1846
Score = 32.3 bits (72), Expect = 9.6
Identities = 92/416 (22%), Positives = 146/416 (35%), Gaps = 69/416 (16%)
Query: 459 SEKSSAASQHSSQMSSDSSRSSSPSVDTS---TDSQASEEIQVLPEERSDTPEVHP---- 511
++ SS ++ H++ + + S+S TS TD+ ++ P +DT
Sbjct: 2148 TDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQAT 2207
Query: 512 PLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPP 571
PLP++ SP + S T ST Q+ P TS S T P P
Sbjct: 2208 PLPVT-SPSSASTGHAIPLLVTD--------TSSASTGQATPLPVTSLSSASTGDTTPLP 2258
Query: 572 LQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQY 631
+ ASS+S +P T S T P+ P +S + P +
Sbjct: 2259 VTDASSVSTGHATSLPVT--SLSSVSTGDTTPL----------PVTSPSSASTGHATPLH 2306
Query: 632 FSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFS----ASGTAASARLFSPLH--SG 685
+ A A G + P P+T + S ++AS +PLH
Sbjct: 2307 VTDASSASTG--------HATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDA 2358
Query: 686 TRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSG---------VSNRKR 736
+ +PL + S H T P T A ++S+G S+
Sbjct: 2359 SSVSTGDTTPLPVTSSSSASSGH-------TTPLPVTDASSASTGDTTPLPVTDTSSAST 2411
Query: 737 KRKVFSPIRS-EPRSPSHSMR---TRSGRLSSSELSPLTPPSSVSSSLSISVSPLA---T 789
P+ S + R T S+ +PL P +S SS+ + +PL T
Sbjct: 2412 GHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPL-PVTSTSSASTGDTTPLPGTDT 2470
Query: 790 SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT 845
S+++ T P L S R ++P+ S+ TPL TP + T
Sbjct: 2471 SSVSTGHTTP--LLVTDASSVSTGDTTRLPVTSPSSA-STGHTTPLPVTDTPSAST 2523
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 82.8 bits (203), Expect = 6e-15
Identities = 69/245 (28%), Positives = 107/245 (43%), Gaps = 29/245 (11%)
Query: 1109 GNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEP-PVKKGRRSRRCGQCPGCQVPEDC 1167
G D K + A+PL PP P +++ P EP P R++R+CG C C DC
Sbjct: 273 GCDSKMAARRRPGAQPLPPP-----PPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDC 327
Query: 1168 GVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKD 1227
G C C DKPKFGG N K+Q C+ R+C LQ+ + L + + S ++
Sbjct: 328 GRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPSVWSESEDGAGSPPPYRRR 383
Query: 1228 SKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQAT 1287
+ SS ++ + + KPT + R +++P + ++ G P P +
Sbjct: 384 KRPSSARRHHLGPTLKPTLATR--------TAQPDHTQAPTKQEAGGGFVLPPPGTDLVF 435
Query: 1288 TPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ--- 1344
+ S P V P +T + V PS K++PP PE E++K
Sbjct: 436 L------REGASSPVQVPGPVAASTEALLQAVDPGLPS--VKQEPPDPEEDKEENKDDSA 487
Query: 1345 KKVAP 1349
K+AP
Sbjct: 488 SKLAP 492
Score = 48.1 bits (113), Expect = 2e-04
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 31/128 (24%)
Query: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
RSR CG C GCQ EDCG C CL P+ G L++Q
Sbjct: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255
Query: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEK 1270
K V+++ + K + +K +S + +Q P P P P S EP +P +
Sbjct: 256 KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ-PLP-----PPPPSQSPEPTEPQPYTNR 309
Query: 1271 SEEGNVSA 1278
+ A
Sbjct: 310 RQNRKCGA 317
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 82.4 bits (202), Expect = 8e-15
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 30/158 (18%)
Query: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID---DSEVVDAT 3896
G G+ I V+EY G +I S + ++R + YD +G Y+F +D D VDA
Sbjct: 255 GWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG-ATYLFDLDYVEDVYTVDAA 313
Query: 3897 MHGNAARFINHSCEPNCYSRVINIDG----QKHIVIFAMRKIYRGEELTYDYKFPIEDA- 3951
+GN + F+NHSC+PN + ID I FA R I GEELT+DY ++
Sbjct: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
Query: 3952 -------SN--------------KLPCNCGAKKCRKFL 3968
SN ++ C CG + CRK+L
Sbjct: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 82.4 bits (202), Expect = 8e-15
Identities = 369/1726 (21%), Positives = 603/1726 (34%), Gaps = 281/1726 (16%)
Query: 2079 VEPDINSTVEHDENRTIAH-SPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYH 2137
V P N+ + E + H SP+S S + I+ D T ++
Sbjct: 7175 VHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTP---HFL 7231
Query: 2138 VISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHST 2197
S++ + S SP R G S+ T V++G S S R S
Sbjct: 7232 ETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSI 7291
Query: 2198 SSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLG 2257
S + S M + +R + ++ A E + K G + ST
Sbjct: 7292 SGSAE--------STMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSEST-FT 7342
Query: 2258 QNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSS- 2316
+TST+ +L V+T L S + + A D V + SSL E+T SS+ S
Sbjct: 7343 LDTSTTPSL---VITHSTMTQRLPHSEITTLVSRGAGD-VPRPSSLPVEETSPPSSQLSL 7398
Query: 2317 -------------EGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKE 2363
S+H+ + L P TT L+ S + P S+S +S E
Sbjct: 7399 SAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTE-VLDASAEPETSSPPSLSSTSVE 7457
Query: 2364 ALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIIN--EHMGSS 2421
L+ + ++ +T T+ SS ++ L S + +S + MG +
Sbjct: 7458 ILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDT 7517
Query: 2422 SRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNN 2481
S + ++ E SS + + +T EE +L E + VL+ G
Sbjct: 7518 SVSTLTPALSNTRKIQSEPASSLT-TRLRETSTSEETSLATE-ANTVLSKVSTGAT--TE 7573
Query: 2482 VS-SDKIGDKGLSMPGVPKAPPMQVE---GSAKELQAPRKRT--VKVTLTPLKMENESQS 2535
VS ++ I SM G P+ M + G+ + A T K+T+T +ES
Sbjct: 7574 VSRTEAISFSRTSMSG-PEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTL 7632
Query: 2536 KNALKESSPASPLQIESTS------------------------PTEPISASENPGDGPVA 2571
++ L ++ +P +E+ S P+ P +P P++
Sbjct: 7633 ESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLS 7692
Query: 2572 QP---SPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARAR-SNM 2627
P SP+ S LPV +L GP D P S+ + S
Sbjct: 7693 LPAVTSPHPVSTTFLAHIPPSPLPVTS---LLTSGPATTTDILGTSTEPGTSSSSSLSTT 7749
Query: 2628 FFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRT 2687
Y ++ E P S++TG ++ G + L+ S T
Sbjct: 7750 SHERLTTYKDTAHTEAVHP--STNTGGTNVATTSSGYKSQSSVLADSSP--------MCT 7799
Query: 2688 VISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKE 2747
+ G L S F E + TE +S+T R+SS G
Sbjct: 7800 TSTMGDTSVLTSTPAFLETRRIQ-------------TELASSLTPGLRESSG---SEGTS 7843
Query: 2748 NGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLS-SLES 2806
+GT+ + G ++K V P +T S ++ S E
Sbjct: 7844 SGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEI 7903
Query: 2807 SRRVHTS----TPSDKNLLDTYNTELL----KSDSDNNNSDDCGNIL---PSDIM----D 2851
+ HTS T + LDT +T L + S + ++ P D+
Sbjct: 7904 TMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPP 7963
Query: 2852 FVLKNTPSMQALGE----SPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPV 2907
+ K PS + SP SS L L GL + ++EPV
Sbjct: 7964 LLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPV 8023
Query: 2908 DSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAV-ISDSGEKRVT-ITEK 2965
+S ++ S +E+ + V T T PS N + V S SG + + +
Sbjct: 8024 TNSPANLSSTS------VEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLAD 8077
Query: 2966 SVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRN 3025
S S + P +++ ++ T TP F + + SS G + L
Sbjct: 8078 SQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATE 8137
Query: 3026 SSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLI----VV 3081
ST VP T + + +S S IS A T P T + ++
Sbjct: 8138 MSTVLSGVPTGATAEVSRTEVTSSSRTS-----ISGFAQLTVSPETSTETITRLPTSSIM 8192
Query: 3082 NQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPT 3141
++ + + QT P G T + T +S+TP+ +ET+++V +TT ++ S
Sbjct: 8193 TESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHS-EMTTLVSRS--P 8249
Query: 3142 SQSLFPSASKGLLPMSHHQHLHSFPAATQSSFP---------PNISNPPSGLL------- 3185
L+PS S + S L S PA T S P P+ S P + LL
Sbjct: 8250 GDMLWPSQS-SVEETSSASSLLSLPATTSPS-PVSSTLVEDFPSASLPVTSLLNPGLVIT 8307
Query: 3186 ---IGVQPPP---DPQLLVSESSQR-TDLSTTVAT----PSSGLKKRPISRLQT------ 3228
+G+ P L S S +R T L TV T PS+ ++ ++T
Sbjct: 8308 TDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPST---HTAVTNVRTSISGHE 8364
Query: 3229 RKNKKLAPSSTPSNIAPSDV--------VSNMTLINFTPSQLPNHP-SLLDLGSLNTSSH 3279
++ L+ S TP +P VS T F S++ P S L G TSS
Sbjct: 8365 SQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSS 8424
Query: 3280 RTVPNIIKRSKSSIMYFEPAPLLPQ-------SVGGTAATAAGTSTISQD--TSHLTSGS 3330
+ + + S+++ P+ + S GT+ + TIS D T +T S
Sbjct: 8425 ERISSATE--GSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLS 8482
Query: 3331 VSGLASSSSVLNV--------------VSMQTTTTP----TSSASVPG--HVTLT----- 3365
S + + S+ + +++ T+TT T S + PG H +T
Sbjct: 8483 TSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSR 8542
Query: 3366 NPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASS 3425
P + P + S+ +AS S + + S+ F L S + S +TA
Sbjct: 8543 TPGDVPWPSLPSVE----EASSVSSSLSSPAMT---STSFFSTLPESISSSPHPVTA--- 8592
Query: 3426 ICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQ 3485
+ L +TT + S E L + + + + + + + +S V N
Sbjct: 8593 LLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGT 8652
Query: 3486 TVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQL 3545
+ L + L+ V PTSP + S + G S S S P P+T
Sbjct: 8653 VI----YKHLSPSSVLADLVTTKPTSPMATTS--TLGNTSVSTSTPA----FPET----- 8697
Query: 3546 PLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECG 3605
+ Q T+SLTSG + Q+T+S + S G
Sbjct: 8698 -----------------------MMTQPTSSLTSGL---REISTSQETSSATERSASLSG 8731
Query: 3606 QPAGQVAVLPEVQV-----TQNPANEQESAEPKTVEEEESNFSSPL 3646
P G + + T P Q + P+ E + S+PL
Sbjct: 8732 MPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPL 8777
Score = 76.3 bits (186), Expect = 6e-13
Identities = 359/1792 (20%), Positives = 624/1792 (34%), Gaps = 309/1792 (17%)
Query: 2079 VEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHV 2138
V+ + S + +D N + SP S E++S SQ + + PSP + S S V
Sbjct: 6192 VDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSV 6251
Query: 2139 IS-------KVPRIRTPSYSPTQRSP-GCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSI 2190
S K+ + T + P RSP R + T TH + P +++ + ++
Sbjct: 6252 TSVPTPTLAKITDMDT-NLEPVTRSPQNLRNTLATSEATTDTHTM----HPSINTAVANV 6306
Query: 2191 GSRRHSTS---SLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVL 2247
G+ ++SP + S + +T + VS+ +A S +
Sbjct: 6307 GTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIF 6366
Query: 2248 GPLNSSTS--LGQNTSTSS-----------NLQRTVVTVGNKNSHLDGSSSSEMKQSSAS 2294
+STS +G ++ TS+ + RT +T ++ S + G+ M +++
Sbjct: 6367 RLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTS-IQGTEKPTMSPDTST 6425
Query: 2295 DLVSKSSSLKG-----EKTKVL-----------------SSKSSEGSAHNVAYPGIPKLA 2332
V+ S+ G E+T S +S+ H+ G +L
Sbjct: 6426 RSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQL- 6484
Query: 2333 PQVHNTTSRELNVSKIGSFAEPSSV--SFSSKEALSFPHLHLRGQRNDRDQHTDSTQSAN 2390
+ TSR V + S P SV + SS LS P + + T +S
Sbjct: 6485 -DLSTLTSR---VPEYISGTSPPSVEKTSSSSSLLSLPAI-----TSPSPVPTTLPESRP 6535
Query: 2391 SSPDEDTEVKT---LKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFL 2447
SSP T + T +K + M + + ++GS+S + + K+T K S+ +
Sbjct: 6536 SSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSH-KIPTTSEDIKDTEKMYPSTNIAV 6594
Query: 2448 EPGQVTTGEEGNLK--PEFMDEVLTPEYMGQRPCNNVSSDKIGDK--GLSMPGVPKAPPM 2503
TT E+ + P + + M V+S I D SMPG + +
Sbjct: 6595 TNVGTTTSEKESYSSVPAYSEPPKVTSPM-------VTSFNIRDTIVSTSMPGSSEITRI 6647
Query: 2504 QVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASE 2563
++E + ++ S S++ + + ++ L +T TE S +E
Sbjct: 6648 EMESTFSLAHG--------------LKGTSTSQDPIVSTEKSAVLHKLTTGATET-SRTE 6692
Query: 2564 NPGDGPVAQPSPNN-TSCQDSQSNNYQNLPVQ-------DRNLMLPDGPK--PQEDGSFK 2613
+ P P++ T D + +LP+ + ++ GP G+F
Sbjct: 6693 VASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFT 6752
Query: 2614 RRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLST 2673
P S+RA G S ++ P +T + + + + ++
Sbjct: 6753 LDTPTTSSRA------------GTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTS 6800
Query: 2674 SDEDDLYYYNFTRTVISS----------GGEERLASHNLFR---------EEEQCDLPKI 2714
+ T +SS L + +L E P +
Sbjct: 6801 FSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNL 6860
Query: 2715 SQLDGVDDGTESDTSVT-----ATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTK 2769
S T+ DT+ +T+ ++ + + ++ D + T
Sbjct: 6861 SSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTT 6920
Query: 2770 SSVGHKN-EPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL-------- 2820
S++GH M +++K + SL L S+ ST + L
Sbjct: 6921 STMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTT 6980
Query: 2821 LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG 2880
+ TE+ S + +LP +T +M L SP + S + +
Sbjct: 6981 AEVSRTEVTSSGRTSIPGPSQSTVLPEI-------STRTMTRLFASPTMTESAEMTIPTQ 7033
Query: 2881 LG-----------LDSNREKDMG-LFEVFSQQLPTTE--------PVDSSVSSSISAEEQ 2920
G LD++ K +Q+ P +E P D S SS S E
Sbjct: 7034 TGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLEN- 7092
Query: 2921 FELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPG 2980
P LPS LS+ T SP S S L V S VT S + +D SP
Sbjct: 7093 ---PSSLPSLLSLPATTSPPPIS---STLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPE 7146
Query: 2981 V---DPTPEGHMTPDHFIQG----HMDADHISSPPCGS----VEQGHGNNQDLTRNSSTP 3029
+ P H + + G + +A H S+ S GH + +S T
Sbjct: 7147 LVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETS 7206
Query: 3030 GLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLY 3089
P+ T ++ ++ S+I ++ + P L+ T + + ++
Sbjct: 7207 KATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRE-TGSSVETSSAIETSA 7265
Query: 3090 VLQTLPNGVTQKI---QLTSS----------------VSSTPSVMETNTSVLGPMGGGLT 3130
VL + G T +I ++TSS +S+T +++ TS + +T
Sbjct: 7266 VLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMT 7325
Query: 3131 LTTGLNPSLPTSQSLFP--SASKGLLPMSHHQHLHSFPAATQSSFPPNISNP---PSGLL 3185
+ T +P TS+S F +++ L ++H P + ++ + PS L
Sbjct: 7326 IKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLP 7385
Query: 3186 IGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRL---QTRKNKKLAPSSTPSN 3242
+ PP QL +S + +S+T+ S S L Q + + L S+ P
Sbjct: 7386 VEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPET 7445
Query: 3243 IAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLL 3302
+P + S I L D ++ S+ V + SS + P+ +L
Sbjct: 7446 SSPPSLSSTSVEI------LATSEVTTDTEKIHPFSNTAVTKV---GTSSSGHESPSSVL 7496
Query: 3303 PQSVGGTAATAAGTSTISQDTS----------------------------HLTSGSVSGL 3334
P S A +A GT +I DTS TS S
Sbjct: 7497 PDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLA 7556
Query: 3335 ASSSSVLNVVSMQTTTTPT---------SSASVPGHVTLTNPRLLGTPDIGSISNLLIKA 3385
+++VL+ VS TT + +S S P T++ +GT S S++L ++
Sbjct: 7557 TEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTES 7616
Query: 3386 SQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGE 3445
++ ++ Q P S + L T+ TPS T + I P + T P G
Sbjct: 7617 AKMTITTQTGPSESTLESTL--NLNTATTPSWVE-THSIVIQGFPHPEMTTSMGRGPGG- 7672
Query: 3446 ADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNS-----MGLEQNKA 3500
+ + +T SS L + + P + T P S L A
Sbjct: 7673 ------VSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPA 7726
Query: 3501 LSSAVQASPTSPGGSPS---SPSSGQRSASPSVPGPTK---PKPKTKRFQLPLDKGNGKK 3554
++ + + T PG S S S +S +R + T+ P T + +G K
Sbjct: 7727 TTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNV-ATTSSGYK 7785
Query: 3555 HKVSHLRTSSSEAHIPDQETTSLTSGTG----------------TPG--AEAEQQDTASV 3596
+ S L SS TS+ + T TPG + + T+S
Sbjct: 7786 SQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSG 7845
Query: 3597 EQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFS-SPLM 3647
+ S P G + + VT P Q + P S FS SP+M
Sbjct: 7846 TKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVM 7897
Score = 68.2 bits (165), Expect = 2e-10
Identities = 324/1548 (20%), Positives = 538/1548 (34%), Gaps = 246/1548 (15%)
Query: 2118 SPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSP-GCRPL-----------PSA 2165
S SPD P + +S H S I T TQ P G L SA
Sbjct: 6127 STKSPDISPEASSS-----HSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSA 6181
Query: 2166 GSPTPTTHEIV-----TVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYS 2220
G+P+ T + V +V + L+ L++ +SLS Q L SP +T
Sbjct: 6182 GTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQ 6241
Query: 2221 RNNVSS-VSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSS-----------NLQR 2268
++ SS VS T T + +D L P+ S +NT +S ++
Sbjct: 6242 EHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINT 6301
Query: 2269 TVVTVGNKNS----HLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVA 2324
V VG +S + S S+ +++++ +++ +S T + S + +
Sbjct: 6302 AVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETT 6361
Query: 2325 YPGIPKLAPQVHNTTSRELNVS-KIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHT 2383
+ I +L RE + S KIGS ++ S+V + A + T
Sbjct: 6362 FSLIFRL---------RETSTSQKIGSSSDTSTVFDKAFTAAT-----------TEVSRT 6401
Query: 2384 DSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSS 2443
+ T S+ +S + TE T+ + ++++ G + + R +T + +S
Sbjct: 6402 ELTSSSRTS-IQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEER----TIATQTGPHRATS 6456
Query: 2444 KSFLE-PGQVTTGEEGN---LKPEFMDEVLT------PEYMGQRPCNNVSSDKIGDKGLS 2493
+ L +TT + G + F L+ PEY+ +V LS
Sbjct: 6457 QGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLS 6516
Query: 2494 MPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIEST 2553
+P + P+ +P V LT L ++ + L S + P + ST
Sbjct: 6517 LPAITSPSPVPTTLPESRPSSP------VHLTSLPTSGLVKTTDML-ASVASLPPNLGST 6569
Query: 2554 SPTEPISASENPGDGPVAQPSPN----NTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQ-- 2607
S P + SE+ D PS N N S+ +Y ++P P P
Sbjct: 6570 SHKIP-TTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEP---PKVTSPMVT 6625
Query: 2608 ----EDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEG 2663
D P S R M + +G++ P S+ K +
Sbjct: 6626 SFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTT-- 6683
Query: 2664 QVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDG 2723
GA + S RT ++S + + E I L + G
Sbjct: 6684 ---GATETS-------------RTEVASSRRTSIPGPDHSTESPDISTEVIPSLP-ISLG 6726
Query: 2724 TESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNC 2783
+++T TR P GT +D P T S G + +
Sbjct: 6727 ITESSNMTIITRTG---PPLGSTSQGT--FTLDTP--------TTSSRAGTHSMATQEFP 6773
Query: 2784 HS-VSRVKTQGQDSLEAQL-SSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDC 2841
HS ++ V + + L + S+E + + PS ++ L K+ S
Sbjct: 6774 HSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKT-IHTTPSPMT 6832
Query: 2842 GNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQL 2901
+ PS +M + LG SPE ++S NL S ++
Sbjct: 6833 SLLTPSLVM--------TTDTLGTSPEPTTSSPPNLSS-----------------TSHEI 6867
Query: 2902 PTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVT 2961
TT+ +++ + + S T T S + S+ +V++DS
Sbjct: 6868 LTTDEDTTAIEA-------------MHPSTSTAATNVETTSSGHGSQSSVLADS------ 6908
Query: 2962 ITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHIS-----SPPCGSVEQGH 3016
EK+ A++ D + GH T + + I S G E
Sbjct: 6909 --EKTKATAPMDTT--------STMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSI 6958
Query: 3017 GNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNS-TDSPGPSQISNAAVQTTPPHLKPAT 3075
N + ++S +VP T + + + T PGPSQ T P + T
Sbjct: 6959 SQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQ------STVLPEISTRT 7012
Query: 3076 EKLIVVNQNM----QPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPM-GGGLT 3130
+ + M + QT P+G T + LT S+T S +T++++ +T
Sbjct: 7013 MTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMT 7072
Query: 3131 LTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQP 3190
P + QS S L S L S PA T S PP S P + I P
Sbjct: 7073 TLMSRGPGDMSWQS-----SPSLENPSSLPSLLSLPATT--SPPPISSTLP--VTISSSP 7123
Query: 3191 PPDPQLLVSESSQRTDLSTT----VATPSSGLKKRPISRLQTRKNKKLAPSSTPS-NIAP 3245
P LL S TD+ T V + L RL T K+ + PS N A
Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183
Query: 3246 SDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSK-------SSIMYFEP 3298
S+V PS H S + + +S T P I ++ S+ + E
Sbjct: 7184 SNVE--------IPSS--GHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLET 7233
Query: 3299 APLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASV 3358
+ + +S+ + T + + +S + + +V S + + + T++ +S S
Sbjct: 7234 SRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISG 7293
Query: 3359 PGHVTLTNPRLLGTPDIGSI--SNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPS 3416
T+ P + T I S +L ++S+ ++ Q P S L TS TPS
Sbjct: 7294 SAESTML-PEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTF--TLDTSTTPS 7350
Query: 3417 TAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSAS 3476
IT ++ LP ++ IT G D + + L +T SSQ L +
Sbjct: 7351 -LVITHSTMTQRLPHSE---ITTLVSRGAGD----VPRPSSLPVEETSPPSSQLSLSAMI 7402
Query: 3477 GPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKP 3536
P + T + +S + V+ + + SS +S SV
Sbjct: 7403 SPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATS 7462
Query: 3537 KPKTKRFQL-PLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGT 3583
+ T ++ P K S S + +PD ETT TS GT
Sbjct: 7463 EVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGT 7510
Score = 66.2 bits (160), Expect = 6e-10
Identities = 329/1547 (21%), Positives = 538/1547 (34%), Gaps = 237/1547 (15%)
Query: 2081 PDINSTVEHDENRTIAHSPTSFTESSSKESQNTAE-IISPPSPDRPPHSQTSGSCYYHVI 2139
P N TV + H TSF + S+ S+ T+ +I+ D + T G
Sbjct: 8052 PSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPG------F 8105
Query: 2140 SKVPRIRT-PSYSPTQRSPGCRPLPSA-GSPTPTTHEIVTVGDPLLSSGLRSIGSRRHST 2197
+ RI+T P+ S T G R S+ G+ T V G P +G + SR T
Sbjct: 8106 FETSRIQTEPTSSLTL---GLRKTSSSEGTSLATEMSTVLSGVP---TGATAEVSRTEVT 8159
Query: 2198 SSLSPQRSKLR--IMSPMRTGNTYSRNNVSSVSTTG------TATDLESSAKVVDHVLGP 2249
SS S +SP + T +R SS+ T T TD S H +
Sbjct: 8160 SSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTV-- 8217
Query: 2250 LNSSTSLGQNTSTSSNLQRTVVTVGNKNSH-----LDGSSSSEM---KQSSASDLVSKSS 2301
+ ST+ N T TV + SH L S +M QSS + S SS
Sbjct: 8218 ---------DISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASS 8268
Query: 2302 SLKGEKTKVLSSKSSE--GSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSF 2359
L T S SS + + P L P + TT R +G EP + S
Sbjct: 8269 LLSLPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDR------MGISREPGTSST 8322
Query: 2360 SSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMG 2419
S+ + S L D + ST +A T V+T +SG ++SS++
Sbjct: 8323 SNLSSTSHERLTTLEDTVDTEDMQPSTHTAV------TNVRT-SISGHESQSSVL----- 8370
Query: 2420 SSSRDRRQKGKKSCKETFKEKH---SSKSFLEPGQV----TTGEEGNLKPEFMDEVLTPE 2472
S S + T E S+ F E ++ T+ L+ E ++
Sbjct: 8371 SDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSA 8430
Query: 2473 YMGQRPCNNVSS---------DKIGDKGLSMPGVPK---APPMQVEGSAKELQAPRKRTV 2520
G + V S + I +G SM G + +P + E
Sbjct: 8431 TEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEA-----------IT 8479
Query: 2521 KVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSC 2580
+++ +P+ E+ ++S ++ SP + E T + + + G A P +++
Sbjct: 8480 RLSTSPIMTES-AESAITIETGSPGATS--EGTLTLDTSTTTFWSGTHSTASPGFSHSEM 8536
Query: 2581 QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSY 2640
S ++P P P +E S S S FF P S
Sbjct: 8537 TTLMSRTPGDVP-------WPSLPSVEEASSVSSSLS--SPAMTSTSFFSTLP----ESI 8583
Query: 2641 GEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASH 2700
P + T G V D L TS E + + +SS E LA+
Sbjct: 8584 SSSPHPVTALLT---------LGPVKTTDMLRTSSEPE----TSSPPNLSSTSAEILATS 8630
Query: 2701 NLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPED 2760
+ ++ E+ +S T + I K + +L +P
Sbjct: 8631 EVTKDREKIH----------------PSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTS 8674
Query: 2761 AGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL 2820
T S++G+ + + + TQ SL + L + +S+ ++T +L
Sbjct: 8675 P----MATTSTLGNTSVSTSTPAFPETMM-TQPTSSLTSGLREISTSQETSSATERSASL 8729
Query: 2821 --------LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGES-----P 2867
TE L + I P + + + + + G + P
Sbjct: 8730 SGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITP 8789
Query: 2868 ESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLP--------TTEPVDSSVSSSISAEE 2919
++ S + G S+R G + + P + P D S S S E+
Sbjct: 8790 KTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEK 8849
Query: 2920 QFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESD--PALL 2977
P L S LS +T+ SP + + S S S RVT V +D L
Sbjct: 8850 TSP-PSSLVS-LSAVTSPSPLYSTPSES-----SHSSPLRVTSLFTPVMMKTTDMLDTSL 8902
Query: 2978 SPGVDPTPEGHMTPDHFI---QGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVP 3034
P P ++T D + + M+ + I +V Q + SS PGL P
Sbjct: 8903 EPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEP 8962
Query: 3035 VSPTVPIQNQKYVPN--STDSPGPSQI------SNAAVQTTPPHLKPATEKLIVVNQNMQ 3086
T P+ + + ST P S+I S + + TP + E +
Sbjct: 8963 SKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTV 9022
Query: 3087 PLYVLQ--TLPNGVTQKIQLTSSVSSTPSVM--ETNTSVLGPMGGGLTLTTGLNPSLPTS 3142
P L T+ + +TQ + + S S M + +T V+ + T ++ T
Sbjct: 9023 PYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQ 9082
Query: 3143 QSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQL----LV 3198
+ S+G L + +F + T S+ S+ L+ P P L +
Sbjct: 9083 TGSPGATSRGTLTLDTST---TFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVE 9139
Query: 3199 SESSQRTDLSTTVATPSSGLKKR----------PISRLQT----RKNKKLAPSSTPSNIA 3244
SS LS+ V T SS + P++ L T + + L SS P +
Sbjct: 9140 EASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSS 9199
Query: 3245 PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ 3304
P ++ S I +++ L++ ++ TS + + P+ +L
Sbjct: 9200 PPNLSSTSAEI-LAITEVTTDTEKLEMTNVVTSGYT--------------HESPSSVLAD 9244
Query: 3305 SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTL 3364
SV A ++ G + + DT+ LTS S + +S+ TS + T
Sbjct: 9245 SVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATE 9304
Query: 3365 TNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAAS 3424
+ L P G+ + + ++ I ++P + Q S S IT S
Sbjct: 9305 KSTVLSSVPT-GATTEV-----SRTEAISSSRTSIPGPA----QSTMSSDTSMETITRIS 9354
Query: 3425 SICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSS--QRDLDSASGPQVSN 3482
+ + IT + A + AS G HS+ QR S +S
Sbjct: 9355 TPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSR 9414
Query: 3483 FTQTVDAPNSMGLEQNKALSSAVQASP-TSPGGSPSSPSSGQRSASP 3528
+ V P+ + +E+N SS V +S TSP S+PS G +SP
Sbjct: 9415 GPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPS-GSSHSSP 9460
Score = 65.5 bits (158), Expect = 1e-09
Identities = 336/1670 (20%), Positives = 594/1670 (35%), Gaps = 245/1670 (14%)
Query: 2068 TCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPH 2127
T KI+ + P + P+I STV + +T + T Q+TA S P
Sbjct: 3205 TLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPT 3264
Query: 2128 SQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGL 2187
TS P+ SPT+ + + SP P + G P G
Sbjct: 3265 GTTS----------------PTKSPTENMLATERVSLSPSP-PEAWTNLYSGTP---GGT 3304
Query: 2188 RSIGSRRHSTSSLSP---------QRSKLRIMSPMRTGNTYSRNNVSSVSTTG-TATDLE 2237
R + S S SP Q+S ++S TG +S + S+ TTG T L
Sbjct: 3305 RQSLATMSSVSLESPTARSITGTGQQSSPELVS-KTTGMEFSMWHGSTGGTTGDTHVSLS 3363
Query: 2238 SSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLV 2297
+S+ +++ P+ S S+ T S + T V+ S + + +Q ++ +
Sbjct: 3364 TSSNILE---DPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVD 3420
Query: 2298 SKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSV 2357
SS + S + G++ +V Q + S I S PS
Sbjct: 3421 EAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGG 3480
Query: 2358 SFSSKEALSFPHLHLRGQRNDRD------QHTDSTQSANSSPDEDT--EVKTLKLSGMSN 2409
SS +++ P + L R + T S SSP E + +V T G+S
Sbjct: 3481 KTSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGIST 3540
Query: 2410 RSSII----------NEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGN 2459
+ + N +G S+ D ++ T S + T N
Sbjct: 3541 TITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSN 3600
Query: 2460 LK----PEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAP 2515
LK P + + T ++ + S +++ G P + K +
Sbjct: 3601 LKVARSPGTISTMHTTSFLAS--STELDSMSTPHGRITVIGTSLVTPSSDASAVKTETST 3658
Query: 2516 RKRTVK----VTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVA 2571
+RT+ TP+ + Q + ++ S S++ E + S D
Sbjct: 3659 SERTLSPSDTTASTPISTFSRVQ-RMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHAST 3717
Query: 2572 QPSPN---NTSCQDSQS----NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSAR-- 2622
+ PN +T DS S + ++L P G ++ + + +++
Sbjct: 3718 KTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATSQLP 3777
Query: 2623 -ARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSA----------EGQV--DGAD 2669
+ ++ +TP RS G + F K+ ++++ GQV A
Sbjct: 3778 FSIGHITSAVTPAAMARSSG---VTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAAT 3834
Query: 2670 DLS----TSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTE 2725
L T+ D + +T +++ E A+ + + E+E+ P + + +
Sbjct: 3835 TLDVIPHTAKTPDATFQRQGQTALTT---EARATSDSWNEKEK-STPSAPWITEMMNSVS 3890
Query: 2726 SDTSVTATTRKSSQIPKRN----GKENGT---ENLKIDRPEDAGEKEHVTKSSVGHKNEP 2778
DT + T SS + N E+GT + K E E T H +
Sbjct: 3891 EDT-IKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTN 3949
Query: 2779 KMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS 2838
++ V+ + ++ A +S + + V T++ ++ ++ T +S
Sbjct: 3950 TVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEP 4009
Query: 2839 DDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFS 2898
+ I D+ ++ ++ + ++ SP S++ + G + S++ + S
Sbjct: 4010 NSFLTIELRDVSPYMDTSSTTQTSIISSPGSTA---ITKGPRTEITSSK-------RISS 4059
Query: 2899 QQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRL---AVISDS 2955
L + S S +I+ F E + + T P S + L A S +
Sbjct: 4060 SFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWT 4119
Query: 2956 G-----EKRVTITEKSVASSE-----SDPALLSPGVDPTPEG------HMT--PDHFI-- 2995
G +R T +EK+ S+ S P+ P V+ T H T P + +
Sbjct: 4120 GTPLATTQRFTYSEKTTLFSKGPEDTSQPS--PPSVEETSSSSSLVPIHATTSPSNILLT 4177
Query: 2996 -QGHMDADHISSPPCGSV----EQGHGNNQDLTRNSSTPGLQVP----------VSPTVP 3040
QGH + S+PP SV G G D++R S PG +P +S
Sbjct: 4178 SQGHSPS---STPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEA 4234
Query: 3041 IQNQKYVPNSTDSPGPS-QISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVT 3099
++ K + +S D+ + + +++ P H KP+ +V ++ T G +
Sbjct: 4235 SRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSS 4294
Query: 3100 QKIQLTSSVSSTPSVMETNTS-VLGPMGGGLTLTTGLNPSLPTSQSLFPSA--SKGLLPM 3156
+ ++ + S + E +TS V T+ T ++ T+ A S G
Sbjct: 4295 ETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSIS 4354
Query: 3157 SHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSS 3216
S HQ + S T S P+ S L+++ESS ++ T T +
Sbjct: 4355 SPHQFITSTNTFTDVSTNPSTS-----------------LIMTESS---GVTITTQTGPT 4394
Query: 3217 GLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVS-NMTLINFTPSQLPNHPSLLDLGSLN 3275
G + L T L + TP + P + S TLI+ P +
Sbjct: 4395 GAATQGPYLLDTSTMPYL--TETPLAVTPDFMQSEKTTLISKGPKDV------------- 4439
Query: 3276 TSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLA 3335
S + P++ + S S + P L ++ +T G T S ++ TS SGL
Sbjct: 4440 --SWTSPPSVAETSYPSSL----TPFLVTTIPPATSTLQGQHTSSPVSA--TSVLTSGLV 4491
Query: 3336 SSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIK-------ASQQ 3388
++ +LN SM+ T + + P + L L T DI +I + K AS
Sbjct: 4492 KTTDMLN-TSMEPVTNSPQNLNNPSNEILAT--LAATTDIETIHPSINKAVTNMGTASSA 4548
Query: 3389 SLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTT---GITAASPSGE 3445
+ PV+ PS+ P + P+++ A +SI + P ++TT G +S +
Sbjct: 4549 HVLHSTLPVSSEPSTATSPMV-----PASSMGDALASISI-PGSETTDIEGEPTSSLTAG 4602
Query: 3446 ADEHYQLQHVNQLLASKTGIHS-SQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSA 3504
E+ LQ +N S + + S + A+ +V +F T + + S A
Sbjct: 4603 RKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVA 4662
Query: 3505 VQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSS 3564
SP P + S+ + G T P L LD S L TS
Sbjct: 4663 SSRLSNSP---PMTISTHMTTTQTGSSGATSKIP------LALD--------TSTLETS- 4704
Query: 3565 SEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVL 3614
A P T T + +D + Q E P+ Q VL
Sbjct: 4705 --AGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVL 4752
Score = 63.9 bits (154), Expect = 3e-09
Identities = 178/858 (20%), Positives = 299/858 (34%), Gaps = 160/858 (18%)
Query: 2865 ESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELP 2924
E PE +SS+ + EG ++ + E + LP + P + + S+ E +
Sbjct: 3090 EPPELTSSQTIAEEEGTTAET-QTLTFTPSETPTSLLPVSSPTEPTARRK-SSPETWASS 3147
Query: 2925 LELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT 2984
+ +P+ S++ T T+ + +S + + + S PA SPG +
Sbjct: 3148 ISVPAKTSLVETTDGTLVTT-----IKMSSQAAQGNSTWPAPAEETGSSPAGTSPG---S 3199
Query: 2985 PEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNS--STPGLQVPVSPTV-PI 3041
PE T ++ + SP S RNS TP VP+ TV P+
Sbjct: 3200 PEMSTT----LKIMSSKEPSISPEIRST----------VRNSPWKTPETTVPMETTVEPV 3245
Query: 3042 QNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQP------LYVLQTLP 3095
Q S G + IS+ TT P P L ++ P + P
Sbjct: 3246 TLQSTALGS----GSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTP 3301
Query: 3096 NGVTQKIQLTSSVS---------------STPSVMETNTSVLGPMGGGLTL-TTG-LNPS 3138
G Q + SSVS S+P ++ T + M G T TTG + S
Sbjct: 3302 GGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVS 3361
Query: 3139 LPTSQSLF------PSASKGLLPMSHH-------------------------QHLHSFPA 3167
L TS ++ P++ L S H Q S
Sbjct: 3362 LSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDE 3421
Query: 3168 ATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLS---------TTVATPSSGL 3218
A S+ + S + +G P L ++ ++Q T L T++ PS G
Sbjct: 3422 AYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGK 3481
Query: 3219 KKR------PISRLQTRKNKKLAPSS----TPSNIAPSDVVSNMTLINFTPSQLPN-HPS 3267
P L+T + A S T +++ + + +++++ T + P +
Sbjct: 3482 TSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTT 3541
Query: 3268 LLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTS-TISQDTSHL 3326
+ +G+ + S+ P + + S E + ++TAA S T++ TS+L
Sbjct: 3542 ITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNL 3601
Query: 3327 TSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP-GHVTLTNPRLLGTPDIGSISNLLIKA 3385
V+ + S ++ S ++T S S P G +T+ L+ S
Sbjct: 3602 ---KVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETST 3658
Query: 3386 SQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGE 3445
S+++L D + P S+ Q + P + + S + ++ S +
Sbjct: 3659 SERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTK 3718
Query: 3446 ADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKAL---- 3501
D + L T + S LD +G +S+ T T AP Q L
Sbjct: 3719 TDPNTPLS---------TFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMI 3769
Query: 3502 SSAVQASPTSPGGSPSSPSSGQRSASPSV----PGPTKPKPKTKRFQLPLDKGNGKKHKV 3557
S A P S G S+ + + S V P PT K + QLP
Sbjct: 3770 SPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTT--------- 3820
Query: 3558 SHLRTSSSEAHIPDQETTSLT---SGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVL 3614
TS+ +P T+L TP A ++Q GQ A+
Sbjct: 3821 ----TSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQ-----------------GQTALT 3859
Query: 3615 PEVQVTQNPANEQESAEP 3632
E + T + NE+E + P
Sbjct: 3860 TEARATSDSWNEKEKSTP 3877
Score = 59.7 bits (143), Expect = 6e-08
Identities = 216/1040 (20%), Positives = 375/1040 (36%), Gaps = 185/1040 (17%)
Query: 2705 EEEQCDLPKISQLDGVDDGTESDTSVT---ATTRKSSQIPKRNGKENGTENLKIDRPEDA 2761
EE K + L V G ++ S T +++R S P ++ + T I R
Sbjct: 9297 EETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTP 9356
Query: 2762 GEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLL 2821
++ T ++ K P S +QG +L++ SS S H++T + +
Sbjct: 9357 LTRKESTDMAITPKTGP--------SGATSQGTFTLDS--SSTASWPGTHSAT-TQRFPQ 9405
Query: 2822 DTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGL 2881
T + + D + PS + V KN+P + S +S S L + G
Sbjct: 9406 SVVTTPMSRGPEDVS--------WPSPLS--VEKNSPPSSLVSSSSVTSPSPLYSTPSG- 9454
Query: 2882 GLDSNREKDMGLFEVFSQ-QLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT 2940
S+ + + +F+ + T+ +D+S+ ++ + + SD S+ +++ T
Sbjct: 9455 ---SSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPN----MNITSDESLAASKATT 9507
Query: 2941 VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPG--VDPTPEGHMTPDHFIQ-- 2996
+ V ++ V T + S P P + P D+ +
Sbjct: 9508 ----ETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTT 9563
Query: 2997 --GHMDADHISSPPCGSVEQG---HGNNQDLTRNSSTPGL--QVPVSPTVPIQNQKYVPN 3049
G I S+ G +QD+T ++ T + ++P T + + +P+
Sbjct: 9564 MPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPS 9623
Query: 3050 S-TDSPGPSQ------ISNAAVQ--TTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQ 3100
S T PGP+Q IS+ V +T P + + E I TLP G +
Sbjct: 9624 SRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSM 9683
Query: 3101 KI---------------QLTSSVS--------STPSVMETNTSVLGPMGGGLTLTTGLNP 3137
++T+ +S ++P +ET S L LTT L+P
Sbjct: 9684 TFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRSSSSLTS--LPLTTSLSP 9741
Query: 3138 SLPTSQSLFPSASKGLLPMSHH--QHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQ 3195
S +L S+ LP++ L +S P S+ P+ V+ P +
Sbjct: 9742 ---VSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSE 9798
Query: 3196 LLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVS---NM 3252
++ +T VA K R S + + LA S T I + S +
Sbjct: 9799 IMTDTEKIHPSSNTAVA------KVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDT 9852
Query: 3253 TLINFTPS-----QLPNHPSL-LDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSV 3306
T+ P+ ++P P+ L G TS+ +I + S +++Y P
Sbjct: 9853 TVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETS--AVLYGVP-------- 9902
Query: 3307 GGTAATA--AGTSTISQDTSHLTSGSVSGLA-----------SSSSVLNVVSMQTTTTPT 3353
T+AT + T +S + H+ S ++ SSSS+++ + T TT
Sbjct: 9903 --TSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQK 9960
Query: 3354 SSASVPGHVTLT---------------NPRLL---------GTPDIGS-ISNLLIKASQQ 3388
SS TLT PR L +P+ S S+L ++ +
Sbjct: 9961 SSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSS 10020
Query: 3389 SLGIQDQPVALPPS-SGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEAD 3447
S + PV PS S PQ S + S ++ + P T T+ P
Sbjct: 10021 SSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSL-------LTPGMVKTTDTSTEPGTSLS 10073
Query: 3448 EHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQA 3507
+ V L AS+ + + + +S V+N T S G E ++S +
Sbjct: 10074 PNLSGTSVEILAASE--VTTDTEKIHPSSSMAVTNVGTT-----SSGHELYSSVSIHSEP 10126
Query: 3508 S-PTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE 3566
S T P G+PS S + S S S+P F+ + H S R ++
Sbjct: 10127 SKATYPVGTPS--SMAETSISTSMPA---------NFETTGFEAEPFSHLTSGFRKTNMS 10175
Query: 3567 AHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECG---QPAGQVAVLPEVQVTQNP 3623
D + + T+ +PG+ Q + + SS K PA Q +P +T
Sbjct: 10176 L---DTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFN 10232
Query: 3624 ANEQESAEPKTVEEEESNFS 3643
A+ + ES F+
Sbjct: 10233 ASPSITESTGITSFPESRFT 10252
Score = 55.8 bits (133), Expect = 8e-07
Identities = 184/859 (21%), Positives = 301/859 (35%), Gaps = 150/859 (17%)
Query: 2908 DSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSV 2967
++ V +SIS+E + + SD+S LT+ S PS L S +G K S+
Sbjct: 2133 ETPVGASISSEVPLPMAITSRSDVSGLTSESTANPS-----LGTASSAGTKLTRTI--SL 2185
Query: 2968 ASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHIS-SPPCGSVEQGHGNNQDLTRNS 3026
+SES + M+ D + S P GS + ++
Sbjct: 2186 PTSES---------------------LVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSA 2224
Query: 3027 STPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQ 3086
PGL S + D+P S V +P P TE + + +
Sbjct: 2225 GPPGLSTVASDVI------------DTPSDGAESIPTVSFSP---SPDTEVTTISHFPEK 2269
Query: 3087 PLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTG----LNPSLPTS 3142
+ +T+ + +T +LTS V+ P ++ P G ++T G + + PT+
Sbjct: 2270 TTHSFRTI-SSLTH--ELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTT 2326
Query: 3143 QSL-----FPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLL 3197
+ F S L A +++ P+ S+ S L+ +
Sbjct: 2327 SPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLI--------NTSI 2378
Query: 3198 VSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTL--- 3254
S + T ++ T SG+ L + ++ S+T +N A S VS+ T
Sbjct: 2379 ASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLD 2438
Query: 3255 ----INFTPSQLP----NHPSLLDLGSLNTSSH-RTVPNIIKR---------SKSSIMYF 3296
+ TPS LP HP L S RT ++ S +S++
Sbjct: 2439 GGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTS 2498
Query: 3297 EPAPLLPQSVGGTA---------ATAAG------TSTISQDTS---HLTSGSVSG----- 3333
PAP SVG T + AG STI T+ HL++ V+G
Sbjct: 2499 VPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATS 2558
Query: 3334 ----LASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLG-TPDIGSISNLLIKASQQ 3388
L +S S S QT TTPTS A+ T + ++ T D S +L+ +
Sbjct: 2559 EASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDT-- 2616
Query: 3389 SLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADE 3448
I V+ PPS + PST ++ AS +LP T +TA P+
Sbjct: 2617 ---ILFSTVSTPPS----------KFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLAT 2663
Query: 3449 HYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSM--GLEQNKALSSAVQ 3506
+ + + + G S + + +TV P+ G+ S +
Sbjct: 2664 SFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLH 2723
Query: 3507 ASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE 3566
S TSP +P + S +V T P T N + + S
Sbjct: 2724 PSSTSP-SKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTAL-----VDSS 2777
Query: 3567 AHIPDQETTSLTSGT----GTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQN 3622
A + LT+G+ + G + + + S G+V + E +T N
Sbjct: 2778 AGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSE--ITTN 2835
Query: 3623 PANEQESAEPKTVEEEESNFSSPLMLWL---QQEQKRKESITEKKPKKG-----LVFEIS 3674
+S PK + + ++ S L+ + K S+T P G L FE S
Sbjct: 2836 RLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFS 2895
Query: 3675 SDDGFQICAESIEDAWKSL 3693
+ S+ +SL
Sbjct: 2896 EVPSLDTKSASLPTPGQSL 2914
Score = 53.5 bits (127), Expect = 4e-06
Identities = 148/644 (22%), Positives = 240/644 (37%), Gaps = 110/644 (17%)
Query: 2902 PTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVT 2961
P SS+++S+ AE LP PS V S T S ++S SG +R
Sbjct: 10532 PDVPETTSSLATSLGAETSTALPRTTPS---VFNRESETTAS-------LVSRSGAERSP 10581
Query: 2962 ITEK-SVASSESD--------PALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSV 3012
+ + V+SSE D PA P V T TP+ F H + D +SS +
Sbjct: 10582 VIQTLDVSSSEPDTTASWVIHPAETIPTVSKT-----TPNFF---HSELDTVSST---AT 10630
Query: 3013 EQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLK 3072
G + + N S L ++P V I ST P T PH +
Sbjct: 10631 SHGADVSSAIPTNISPSELDA-LTPLVTISG---TDTSTTFP---------TLTKSPH-E 10676
Query: 3073 PATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLT 3132
T + + + +T+PN + T S++++P ET++++ P+ +T++
Sbjct: 10677 TETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGA-ETSSAI--PI---MTVS 10730
Query: 3133 TGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPP 3192
G L TSQ T S N++ P L P
Sbjct: 10731 PGAE-DLVTSQ------------------------VTSSGTDRNMTIPTLTL-----SPG 10760
Query: 3193 DPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA----PSDV 3248
+P+ + S + + T+ A P+S + +SRL T LA ++ +N A P +
Sbjct: 10761 EPKTIASLVTH-PEAQTSSAIPTSTISPA-VSRLVTSMVTSLAAKTSTTNRALTNSPGEP 10818
Query: 3249 VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGG 3308
+ ++L+ P P + + S T P++ + P P + V G
Sbjct: 10819 ATTVSLVTHPAQTSPTVPWTTSIFFHSKSD--TTPSMTTSHGAESSSAVPTPTVSTEVPG 10876
Query: 3309 ------TAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHV 3362
T++ A ++TI T L+ G S ++ + TPT S VPG V
Sbjct: 10877 VVTPLVTSSRAVISTTIPILT--LSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVV 10934
Query: 3363 T--LTNPRLLGTPDIGSISNLL--------IKASQQSLGIQDQPVALPPSSGMFPQLGTS 3412
T +T+ R + + I ++ L + S + P LP GM L S
Sbjct: 10935 TSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVAS 10994
Query: 3413 QTPSTAAITAASSICVLPST-QTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRD 3471
T+ T ++ + P +TT A S EA ++ T + +S
Sbjct: 10995 SRAVTS--TTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSP-EVPGVVTSLVTSSSG 11051
Query: 3472 LDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGS 3515
++S S P + ++ SM SSAV SPG S
Sbjct: 11052 VNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVS 11095
Score = 52.0 bits (123), Expect = 1e-05
Identities = 189/979 (19%), Positives = 359/979 (36%), Gaps = 134/979 (13%)
Query: 2777 EPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNN 2836
E M S SR + Q ++ +S+ E R+ TS + T +TE+ + +
Sbjct: 9033 EDSMTQVMSSSRGPSPDQSTMSQDIST-EVITRLSTSP------IKTESTEMTITTQTGS 9085
Query: 2837 NSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG----LGLDSNREKDMG 2892
L D + T S + G S S + L++ G L S E
Sbjct: 9086 PGATSRGTLTLDTSTTFMSGTHSTASQGFS-HSQMTALMSRTPGDVPWLSHPSVEEASSA 9144
Query: 2893 LFEVFSQQLPTTEPVDSSVSSSISAEEQFELPL------------ELPSDLSVLTTRSPT 2940
F + S + ++ PV S++ SI + LP+ EL S T SP
Sbjct: 9145 SFSLSSPVMTSSSPVSSTLPDSIHSSS---LPVTSLLTSGLVKTTELLGTSSEPETSSPP 9201
Query: 2941 VPSQNPSRLAVIS----DSGEKRVTITEKSVASSESDPALLSPGVD-----------PTP 2985
S + + I+ D+ + +T S + ES ++L+ V PT
Sbjct: 9202 NLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTG 9261
Query: 2986 EGHM---TPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQ 3042
+ ++ TP + S G +E ST VP T +
Sbjct: 9262 DTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVS 9321
Query: 3043 NQKYVPNS-TDSPGPSQI---SNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV 3098
+ + +S T PGP+Q S+ +++T P T K ++ +T P+G
Sbjct: 9322 RTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRK-----ESTDMAITPKTGPSGA 9376
Query: 3099 TQKIQLTSSVSSTPSVMETNTS---------VLGPMGGGLTLTTGLNPSLPTSQSLFPSA 3149
T + T SST S T+++ V PM G + +P L ++ PS+
Sbjct: 9377 TSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSP-LSVEKNSPPSS 9435
Query: 3150 SKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQL-----------LV 3198
++ L+S P+ + S P +++ + +++ D L +
Sbjct: 9436 LVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNIT 9495
Query: 3199 SESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLI--- 3255
S+ S +TT + S ++T + SS+P P+ V+S +
Sbjct: 9496 SDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSI 9555
Query: 3256 --NFTPSQLPNHPSLLDLGSLNTSS-------HRTVPNIIKRSKSS-IMYFEPAPLLPQ- 3304
N + +P + + + SS RT +I +++S ++Y P+ P+
Sbjct: 9556 RDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEV 9615
Query: 3305 ------SVGGTAATAAGTSTISQDTSH--LTSGSVSGLASSSSVLNVVSMQTTTTPTSSA 3356
T+ ST+S D S +T S S + + S+ + + + + TS
Sbjct: 9616 SRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQV 9675
Query: 3357 SVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPS 3416
++P ++T L GT S + + S+ + + P +L +S F + T + S
Sbjct: 9676 TLPLGTSMT--FLSGT---HSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVET-TRSSSS 9729
Query: 3417 TAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSAS 3476
++ +S+ + ST + +SPS + L T + + + ++S
Sbjct: 9730 LTSLPLTTSLSPVSST----LLDSSPSSPLP---VTSLILPGLVKTTEVLDTSSEPKTSS 9782
Query: 3477 GPQVSNFTQTVDAPNSMGLEQNK--ALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPT 3534
P +S+ + + A + + + K S+ A + S SS + ++ P+
Sbjct: 9783 SPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPS 9842
Query: 3535 KPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTA 3594
+ + + S IP + T SLT G + ++T
Sbjct: 9843 ----------MGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGF---RETSTSEETT 9889
Query: 3595 SVEQSSQKECGQPAGQVAVLPEVQVTQN-----PANEQESAEPKTVEEEESNFSSPLMLW 3649
S+ ++S G P + ++ + P ++Q + P + E + SS M+
Sbjct: 9890 SITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMM- 9948
Query: 3650 LQQEQKRKESITEKKPKKG 3668
+ + +IT +K G
Sbjct: 9949 ---SESTQMTITTQKSSPG 9964
Score = 50.1 bits (118), Expect = 4e-05
Identities = 155/738 (21%), Positives = 269/738 (36%), Gaps = 103/738 (13%)
Query: 2898 SQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGE 2957
S + T VD+S+ + S+ + L+ D+SV + + + + +PS V+++ G
Sbjct: 4781 SSLVKTAGKVDTSLETVTSSPQSMSNTLD---DISVTSAATTDIETTHPSINTVVTNVGT 4837
Query: 2958 KRVTITEKSVASSESDPA-LLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVE--- 3013
S S+ +P+ + SP V + T I + S+
Sbjct: 4838 TGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKL 4897
Query: 3014 QGHGNNQDLTRNSST---PGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPH 3070
+ +Q++T ++ T P ++ + T + +ST PGP Q + + +T +
Sbjct: 4898 RETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETN 4957
Query: 3071 LKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLT 3130
+ +T ++ ++ + QT P+G T + T S+T ++++ L
Sbjct: 4958 TRLSTSP--IMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQ-LD 5014
Query: 3131 LTTGLNPSLPTSQSLF--PSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGV 3188
+TT L +P S PS K P S S PA T S S P L
Sbjct: 5015 VTT-LMSRIPQDVSWTSPPSVDKTSSPSS----FLSSPAMTTPSLIS--STLPEDKLSS- 5066
Query: 3189 QPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSN---IAP 3245
P LL S + TD+ T P + + + +K LA S + I P
Sbjct: 5067 ---PMTSLLTSGLVKITDILRTRLEPVTS----SLPNFSSTSDKILATSKDSKDTKEIFP 5119
Query: 3246 SDVVSNMTLINFTPSQLPNH-PSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ 3304
S + + T + S +H P+L D + ++ + + +PAP
Sbjct: 5120 S-INTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVG---------DPAPSTSM 5169
Query: 3305 SVGGTAATA--------------AGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTT 3350
V G++ T TST SQ++S T S + + VS T
Sbjct: 5170 PVHGSSETTNIKREPTYFLTPRLRETST-SQESSFPTDTSFLLSKVPTGTITEVS-STGV 5227
Query: 3351 TPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLG 3410
+S S P H T P T +I + IK + I Q A PP S
Sbjct: 5228 NSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQ--ASPPES------- 5278
Query: 3411 TSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQR 3470
+S LP +T ++ + + V L+ G
Sbjct: 5279 -------------ASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPG------ 5319
Query: 3471 DLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSP------SSGQR 3524
++ + P V T +V + L + A++S S TSP PSSP +
Sbjct: 5320 NVSWMTTPPVEE-TSSVSS-----LMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVL 5373
Query: 3525 SASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTP 3584
+ V G T P+ T P + ++ T+ +EA + T++T+ GT
Sbjct: 5374 VTTTDVLGTTSPESVTS--SPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTN-VGTS 5430
Query: 3585 GAEAEQQDTASVEQSSQK 3602
G+ + Q + + + K
Sbjct: 5431 GSGHKSQSSVLADSETSK 5448
Score = 49.7 bits (117), Expect = 6e-05
Identities = 160/802 (19%), Positives = 288/802 (35%), Gaps = 115/802 (14%)
Query: 2767 VTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESS-RRVHTSTPSDKNLLDTYN 2825
++K G E +S S++ T D + RV TS+ K+ T
Sbjct: 5211 LSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270
Query: 2826 TELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDS 2885
T+ +S ++++ LP D + + P S + L+ +G G
Sbjct: 5271 TQASPPESASHST------LPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPG----- 5319
Query: 2886 NREKDMGLFEVFSQQLPTTEPVD--SSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPS 2943
+ TT PV+ SSVSS +S+ + S V +T ++PS
Sbjct: 5320 ------------NVSWMTTPPVEETSSVSSLMSSPA-------MTSPSPVSSTSPQSIPS 5360
Query: 2944 QNPSRLAVISDSGEKRVTITE----KSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHM 2999
S L V + VT T+ S S S P LS P + H
Sbjct: 5361 ---SPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMH 5417
Query: 3000 DADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQI 3059
+ + + G+ GH + + +S T +S T + + ++ + +QI
Sbjct: 5418 HSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQI 5477
Query: 3060 SNAAVQTTPPHLKPAT--EKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMET 3117
+ P L+ ++ EK + + +P G + T SS S+ +
Sbjct: 5478 QTEPTASLSPRLRESSTSEK---TSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDL 5534
Query: 3118 NTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNI 3177
+ + P ++TG+ L TS + SA TQ++ P
Sbjct: 5535 DRPTIAP-----DISTGMITRLFTSPIMTKSAE--------------MTVTTQTTTPGAT 5575
Query: 3178 SNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPS 3237
S G+ P ++S T +T S G I+ L++R ++
Sbjct: 5576 SQ-------GILP--------WDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWM 5620
Query: 3238 STP---------SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKR 3288
+TP S ++PS + S + + +P +P+ P L + +L TS T N++
Sbjct: 5621 TTPPVEETSSGFSLMSPS-MTSPSPVSSTSPESIPSSP--LPVTALLTSVLVTTTNVLGT 5677
Query: 3289 SKSSIMYFEPAPLLPQS------VGGTAATAAGTSTISQDTSHLTSG-SVSGLASSSSVL 3341
+ + P L + TA T A +++ +T+ G S+SG S SSV
Sbjct: 5678 TSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVP 5737
Query: 3342 NVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPP 3401
T+P G +++ TP S G++D +
Sbjct: 5738 ADSHTSKATSPMGITFAMGDTSVST----STPAFFETRIQTESTSSLIPGLRDTRTSEEI 5793
Query: 3402 SSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLAS 3461
++ S+ P+T T S V+ S++TT + + + + + +L
Sbjct: 5794 NTVTETSTVLSEVPTTTT-TEVSRTEVITSSRTT--ISGPDHSKMSPYISTETITRLSTF 5850
Query: 3462 KTGIHSSQRDLDSASGP--QVSNFTQTVDAPNSMGLEQNKA--------LSSAVQASPTS 3511
S++ + + +GP +S T T+D ++ E + S ++
Sbjct: 5851 PFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRST 5910
Query: 3512 PGGSPSSPSSGQRSASPSVPGP 3533
G S SP S + ++SPS P P
Sbjct: 5911 KGVSWQSPPSVEETSSPSSPVP 5932
Score = 47.8 bits (112), Expect = 2e-04
Identities = 79/345 (22%), Positives = 132/345 (38%), Gaps = 39/345 (11%)
Query: 703 TPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRL 762
T ++ S + S+TL ++A TS V N SP E ++ T +
Sbjct: 761 TKTKPSSAVLSSMTL----SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETT 816
Query: 763 SSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTF--PSHSLTQSGESAEKNQRP---R 817
S + P +S SS ++S + S + TF+ PS L SGE E+ P +
Sbjct: 817 DSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQ 876
Query: 818 KQTSAP---AEPFSSSSPTPLFP----WFTPGSQ---------------TERGRNKDKAP 855
+TS S+S PTP+FP W T +Q T + A
Sbjct: 877 PETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSAL 936
Query: 856 EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEK 915
++S + ++ D + + K G +++ +S
Sbjct: 937 PKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATV 996
Query: 916 VVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKG---RGNLEKT 972
+V + + ++S+ +AT ++ S+ T+ T+ G T I I KG G L+ +
Sbjct: 997 MVSKFTSPATSSMEATSIREPSTTILTTETTNGP-GSMAVASTNIPIGKGYITEGRLDTS 1055
Query: 973 NLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLP 1017
+L +G TA S +T T + +V S S SM A P
Sbjct: 1056 HLPIGTTASS----ETSMDFTMAKESVSMSVSPSQSMDAAGSSTP 1096
Score = 47.4 bits (111), Expect = 3e-04
Identities = 158/767 (20%), Positives = 270/767 (35%), Gaps = 123/767 (16%)
Query: 2995 IQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP 3054
I GH +SP S G D+T ++S G S T I+ V
Sbjct: 4262 IPGHTKPSKATSPLVTSHIMG-----DITSSTSVFGS----SETTEIETVSSVNQGLQER 4312
Query: 3055 GPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSS---VSST 3111
SQ++++A +T+ ++ Q + T + Q I T++ VS+
Sbjct: 4313 STSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTN 4372
Query: 3112 PSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQS 3171
PS TS++ G+T+TT P+ +Q + LL S +L P A
Sbjct: 4373 PS-----TSLIMTESSGVTITTQTGPTGAATQGPY------LLDTSTMPYLTETPLAVTP 4421
Query: 3172 SFPPN-----ISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRL 3226
F + IS P + PP SS L TT+ +S L+ + S
Sbjct: 4422 DFMQSEKTTLISKGPKD--VSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTS-- 4477
Query: 3227 QTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLL---------------DL 3271
+P S S + S +V ++N + + N P L D+
Sbjct: 4478 --------SPVSATS-VLTSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDI 4528
Query: 3272 GSLNTSSHRTVPNIIKRSKSSIMY------FEP----APLLPQSVGGTAATAAG------ 3315
+++ S ++ V N+ S + +++ EP +P++P S G A +
Sbjct: 4529 ETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPMVPASSMGDALASISIPGSET 4588
Query: 3316 TSTISQDTSHLTSG--------SVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTL--T 3365
T + TS LT+G ++ S+ +L+ VS+ T T T T
Sbjct: 4589 TDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPT 4648
Query: 3366 NPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASS 3425
+ PDI S+++ + S P + + T+QT S+ A S
Sbjct: 4649 PAQSTKFPDIFSVASSRLSNS--------------PPMTISTHMTTTQTGSSG---ATSK 4691
Query: 3426 ICVLPSTQTTGITAASPS--GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNF 3483
I + T T +A +PS E H ++ T +++ +D+ + P F
Sbjct: 4692 IPLALDTSTLETSAGTPSVVTEGFAHSKI---------TTAMNNDVKDVSQTNPP----F 4738
Query: 3484 TQTVDAPNSMGLEQNKALSSAVQASPT-SPGGSPSSPSSGQRSASPSVPGPTKPKPKTKR 3542
+P+S L S+V +P SP S SS S+ G +T
Sbjct: 4739 QDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVT 4798
Query: 3543 FQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQK 3602
V+ T+ E P T + + GT G+ E T S K
Sbjct: 4799 SSPQSMSNTLDDISVTSAATTDIETTHPSINT--VVTNVGTTGSAFESHSTVSAYPEPSK 4856
Query: 3603 ECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITE 3662
P + + + ++++ ++ +T E S+ + L ++ + T
Sbjct: 4857 -VTSPNVTTSTMEDTTISRSIPKSSKTTRTET--ETTSSLTPKLRETSISQEITSSTETS 4913
Query: 3663 KKPKK---GLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARL 3706
P K G E+S D + S +S +N RL
Sbjct: 4914 TVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRL 4960
Score = 46.6 bits (109), Expect = 5e-04
Identities = 140/663 (21%), Positives = 235/663 (35%), Gaps = 96/663 (14%)
Query: 2902 PTTEPVDSSVSSSISAEEQFELPL---ELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEK 2958
P T P S+++S AE +P E+P ++ L T S V S + L I GE
Sbjct: 11013 PETTP---SMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTL--ILSPGEL 11067
Query: 2959 RVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGN 3018
T + + +E+ A+ +P V P G +TP + + I S E
Sbjct: 11068 ETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTP 11127
Query: 3019 NQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHL-----KP 3073
+ + + VSP VP V + S A TT P L +P
Sbjct: 11128 SMATSHGVEASSAVLTVSPEVPGMVTSLVTS----------SRAVTSTTIPTLTISSDEP 11177
Query: 3074 ATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTT 3133
T +V + + + + TL T + +TS V+S+ S +++ T+ +
Sbjct: 11178 ETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDS 11237
Query: 3134 GLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPD 3193
+ + S+ P+ + + L + PA + S+ P S L +
Sbjct: 11238 WVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTM----- 11292
Query: 3194 PQLLVS-ESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNM 3252
P + S E+ + +STT++ G+ ++ L T + + S+T + S S
Sbjct: 11293 PSTVTSPEAESSSAISTTISPGIPGV----LTSLVTSSGRDI--SATFPTVPESPHESEA 11346
Query: 3253 TLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAAT 3312
T + HP++ +T+ RT PN + P + S G A +
Sbjct: 11347 T------ASWVTHPAV-----TSTTVPRTTPNYSHSEP------DTTPSIATSPGAEATS 11389
Query: 3313 AAGTSTISQDTSHLTSGSVSGLASSSSV----LNVVSMQTTTTPTSSASVPGHVTLTNPR 3368
T T+S D + + V+ + +S+ L + S + TT + H + P
Sbjct: 11390 DFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPT 11449
Query: 3369 LLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQL-GTSQTPSTAAIT---AAS 3424
L +P + L+ +S S+ FP L T P T AI A
Sbjct: 11450 LPVSPGASKMLTSLVISSGTD------------STTTFPTLTETPYEPETTAIQLIHPAE 11497
Query: 3425 SICVLPST----------QTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDS 3474
+ ++P T T + SP EA S T I DL +
Sbjct: 11498 TNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASS----------AVSTTTISPDMSDLVT 11547
Query: 3475 ASGPQVSNFTQTVDAPNSMGLEQNKA----LSSAVQASPTSPGGSPSSPSSGQRSASPSV 3530
+ P T T S + + L+ + S T G P+ G +A V
Sbjct: 11548 SLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMV 11607
Query: 3531 PGP 3533
P
Sbjct: 11608 TSP 11610
Score = 45.1 bits (105), Expect = 0.001
Identities = 115/548 (20%), Positives = 191/548 (34%), Gaps = 56/548 (10%)
Query: 2901 LPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVI-SDSGEKR 2959
+P T P S S + P S TT SP + S + +D+
Sbjct: 11502 VPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTF 11561
Query: 2960 VTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNN 3019
T++E + L P T P+ +G A + + P G
Sbjct: 11562 PTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTT 11621
Query: 3020 QDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPG-PSQISNAAVQTTPPHLKPATEKL 3078
T S PG+ + +P T SPG P +++A P T+
Sbjct: 11622 ---TIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATH-------PGTQTG 11671
Query: 3079 IVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPS 3138
V P T+ + VT Q ++ VS T S ++ P+ +P
Sbjct: 11672 FTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPV-------MATSPR 11724
Query: 3139 LPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP---PSGLLIGVQPPPDPQ 3195
S ++ + S G M Q + S AAT ++ P +P + L+ P +
Sbjct: 11725 TEASSAVLTTISPGAPEMVTSQ-ITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETS 11783
Query: 3196 LLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLI 3255
S+ +S T A+ L RP + T P+ T S++ +V+ + +
Sbjct: 11784 KTFPASTVFPQVSETTAS----LTIRPGAETSTA-----LPTQTTSSLFTL-LVTGTSRV 11833
Query: 3256 NFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAG 3315
+ +P+ P + L+T +I S S+ E LL S +T+
Sbjct: 11834 DLSPTASPGVSA--KTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTL 11891
Query: 3316 TSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDI 3375
T T+S S L+S S++ + V S T T+P+ ++ P + T +
Sbjct: 11892 TLTVSPAVSGLSSASIT----TDKPQTVTSWNTETSPSVTSVGPPEFSRT---------V 11938
Query: 3376 GSISNLLIKASQQSLGIQDQPVALPPSSGMFPQ--LGTSQTPSTAAITAASSICVLPSTQ 3433
+ LI + + P G+ P L T+ +T T SS V +T
Sbjct: 11939 TGTTMTLIPSEMPT------PPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTT 11992
Query: 3434 TTGITAAS 3441
T A S
Sbjct: 11993 TFNTLAGS 12000
Score = 44.7 bits (104), Expect = 0.002
Identities = 132/676 (19%), Positives = 228/676 (33%), Gaps = 79/676 (11%)
Query: 2821 LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG 2880
LDT + L N D S + + P + + + S+S + G
Sbjct: 2900 LDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFT 2959
Query: 2881 LGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT 2940
+ + M E T +P +S S S + + S S LTT T
Sbjct: 2960 ETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFST 3019
Query: 2941 -VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHM 2999
+++ S + IS S EK + + ++S L P + P I H+
Sbjct: 3020 GQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPN--------ILVHL 3071
Query: 3000 DADHISSPPCGSVEQGHGNNQDLTRN--------------------SSTPGLQVPVS-PT 3038
++ P ++ +LT + S TP +PVS PT
Sbjct: 3072 QTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPT 3131
Query: 3039 VPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQ----PLYVLQTL 3094
P +K P + S + V+TT L + Q P +
Sbjct: 3132 EPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSS 3191
Query: 3095 PNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNP------SLPTSQSLFPS 3148
P G + + +S+T +M + + P + T +P ++P ++ P
Sbjct: 3192 PAGTSPG---SPEMSTTLKIMSSKEPSISPE---IRSTVRNSPWKTPETTVPMETTVEPV 3245
Query: 3149 ASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLS 3208
+ S + P T S N + + + P P S
Sbjct: 3246 TLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTR 3305
Query: 3209 TTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSL 3268
++AT SS + P +R T ++ +P ++VS T + F+ +
Sbjct: 3306 QSLATMSSVSLESPTARSITGTGQQSSP----------ELVSKTTGMEFSMWHGSTGGTT 3355
Query: 3269 LDLG-SLNTSSH---------RTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTST 3318
D SL+TSS+ +V ++ +SK + +P +V AA T
Sbjct: 3356 GDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQT 3415
Query: 3319 I---------SQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP----GHVTLT 3365
+ S TSGS L +S V N + + +T TS S+P G +LT
Sbjct: 3416 SRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLT 3475
Query: 3366 NPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASS 3425
NP T S+++ I + + P++G Q + S +T A +
Sbjct: 3476 NPSGGKTSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPT 3535
Query: 3426 ICVLPSTQTTGITAAS 3441
+ + T G + S
Sbjct: 3536 PGISTTITTMGTNSIS 3551
Score = 44.3 bits (103), Expect = 0.002
Identities = 130/571 (22%), Positives = 222/571 (38%), Gaps = 90/571 (15%)
Query: 2909 SSVSSSISAEEQFELPLEL-PSDLSVLTTRSPTV---PSQNPSRLAVISDSGEKRVTITE 2964
S+VS++ + + +L L PS + +T PT+ P + + ++ E T++
Sbjct: 11531 SAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSG 11590
Query: 2965 K----SVASSESDPALL-SPGVDP---TPEGHMTPDHFIQGHMDADHISSPPCGS----- 3011
S S++ P+++ SPGVD P + P I G + + SS S
Sbjct: 11591 TIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPS--IPGVVTSQVTSSATDTSTAIPT 11648
Query: 3012 VEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTP--- 3068
+ G + +++ PG Q TVPI+ VP+S S +++ +TP
Sbjct: 11649 LTPSPGEPETTASSATHPGTQTGF--TVPIRT---VPSSEPDTMASWVTHPPQTSTPVSR 11703
Query: 3069 -----PHLKP-ATEKLIVVNQNMQPLYVLQTLPNGVTQKI--QLTSSVSSTPSVMETNTS 3120
H P AT + + VL T+ G + + Q+TSS ++T + + T T
Sbjct: 11704 TTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTH 11763
Query: 3121 VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP 3180
G L+T +P TS++ FP+++ L P A S+ P +
Sbjct: 11764 SPGMPETTALLST--HPRTETSKT-FPASTVFPQVSETTASLTIRPGAETSTALP--TQT 11818
Query: 3181 PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP 3240
S L LLV+ +S R DLS T A+P K P+S + + P+ST
Sbjct: 11819 TSSLFT---------LLVTGTS-RVDLSPT-ASPGVSAKTAPLSTHPGTETSTMIPTSTL 11867
Query: 3241 SN---------IAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKS 3291
S S ++ + + T S S L S+ T +TV + +
Sbjct: 11868 SLGLLETTGLLATSSSAETSTSTLTLTVSPAV---SGLSSASITTDKPQTVTSWNTETSP 11924
Query: 3292 SIMYFEPAPLLPQSVGGTAATAAGT---------------------STISQDTSHLTSGS 3330
S+ P P ++V GT T + +T+ + T+ T+GS
Sbjct: 11925 SVTSVGP-PEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGS 11983
Query: 3331 VSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSL 3390
+A +++ N ++ T T+ PG TL + + S + S +
Sbjct: 11984 SPTVAKTTTTFNTLAGSLFTPLTT----PGMSTLASESVTSRTSYNHRS-WISTTSSYNR 12038
Query: 3391 GIQDQPVALPPSSGMFPQLGTSQTPSTAAIT 3421
+ P +S P + TS PS+ A T
Sbjct: 12039 RYWTPATSTPVTSTFSPGISTSSIPSSTAAT 12069
Score = 43.9 bits (102), Expect = 0.003
Identities = 103/477 (21%), Positives = 172/477 (36%), Gaps = 35/477 (7%)
Query: 359 RIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAIS 418
R+ SS +++T Q++ GA + A +T +F+ ++ +
Sbjct: 9941 RLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLM 10000
Query: 419 SRIIKTPR----RFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSS 474
SR + P F+E + + ++P+ + P S S S + M
Sbjct: 10001 SRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVK 10060
Query: 475 DSSRSSSPSVDTSTD-SQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSV 533
+ S+ P S + S S EI E +DT ++HP ++ + ++ SV
Sbjct: 10061 TTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSV 10120
Query: 534 SERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLA 593
S S S+ T + T S + S+S P T +P S + T + L
Sbjct: 10121 SIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHL---TSGFRKTNMSLD 10177
Query: 594 SPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRP 653
+ + + P +L+ +TS S P + +++Y + I I F
Sbjct: 10178 TSSVTPTNTPSSPGSTHLLQSSKTDFTS-SAKTSSPDWPPASQYTE---IPVDIITPFNA 10233
Query: 654 PPLTPEDVGFA----SGFSASGTAASARLFSP-LHSGTRFDMHKRSP-LLRAPRFTPSEA 707
P E G S F+ S T ++ L + L S P L A +
Sbjct: 10234 SPSITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTG 10293
Query: 708 HSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSG------R 761
R P +RT +G + +S +P+ P S S T S
Sbjct: 10294 VPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPV---PFSSSTFTTTDSSTIPALHE 10350
Query: 762 LSSSELSP------LTPPSSVSSSLSISVSPLATSALNPTFTFPSHSL-TQSGESAE 811
++SS +P L SS + + VS L TS+ P T S L T+ ES E
Sbjct: 10351 ITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSS-QPGRTSSSPILDTRMTESVE 10406
Score = 43.5 bits (101), Expect = 0.004
Identities = 135/607 (22%), Positives = 226/607 (37%), Gaps = 109/607 (17%)
Query: 2897 FSQQLPTTEPVDSSVSSSISAEEQFELPL-----ELPSDLSVLTTRSPTVPSQNPSRLAV 2951
+S P T P S+++S AE + P ++P ++ T S T S L +
Sbjct: 11368 YSHSEPDTTP---SIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTL 11424
Query: 2952 ISDSGEKRVT---ITEKSVASSESDPAL-LSPGVDPTPEGHMTPDHFIQGHMDA------ 3001
SGE T IT +S + P L +SPG M I D+
Sbjct: 11425 --SSGEPETTTSFITYSETHTSSAIPTLPVSPGASK-----MLTSLVISSGTDSTTTFPT 11477
Query: 3002 --DHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQI 3059
+ P +++ H + +TP S T +P + SPGP
Sbjct: 11478 LTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTT-------LPVAITSPGPEAS 11530
Query: 3060 SNAAVQTTPPHLKPATEKLIVVNQN---------MQPLYVLQTLPNGVTQKIQLTSSVSS 3110
S + T P + L+ + + Y +T +T + +++VS
Sbjct: 11531 SAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSG 11590
Query: 3111 T-PSVM----ETNTSVLGPMG----GGLTLTTGLNPSLP---TSQ-------------SL 3145
T P+ +T S++ G G+ TT + PS+P TSQ +L
Sbjct: 11591 TIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTT-IPPSIPGVVTSQVTSSATDTSTAIPTL 11649
Query: 3146 FPSASKGLLPMSHHQHLHSFPAATQSSFPPNI----SNPPSGLLIGVQPPPDPQLLVSES 3201
PS + S H TQ+ F I S+ P + V PP VS +
Sbjct: 11650 TPSPGEPETTASSATH-----PGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRT 11704
Query: 3202 SQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPS--NIAPSDVVSNMTLINFTP 3259
+ S+ ATP R T + + + +P + S + S+ + T
Sbjct: 11705 TSSFSHSSPDATPVMATSPR------TEASSAVLTTISPGAPEMVTSQITSSGAATSTTV 11758
Query: 3260 SQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTI 3319
L + P + + +L ++ RT + SK+ F + + PQ + TA+ T
Sbjct: 11759 PTLTHSPGMPETTALLSTHPRT-----ETSKT----FPASTVFPQV---SETTASLTIRP 11806
Query: 3320 SQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSIS 3379
+TS + ++SS+ ++ T+ S + PG T P L T G+ +
Sbjct: 11807 GAETS-----TALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAP--LSTHP-GTET 11858
Query: 3380 NLLIKASQQSLGIQDQPVALPPSSGMFPQLGT---SQTPSTAAITAASSICVLPSTQTTG 3436
+ +I S SLG+ + L SS T + +P+ + +++AS P T T+
Sbjct: 11859 STMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSW 11918
Query: 3437 ITAASPS 3443
T SPS
Sbjct: 11919 NTETSPS 11925
Score = 42.0 bits (97), Expect = 0.012
Identities = 132/626 (21%), Positives = 231/626 (36%), Gaps = 81/626 (12%)
Query: 433 DYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQA 492
D D + L +P A S++ SA+S S+ + S+SPS+
Sbjct: 2919 DSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGH----- 2973
Query: 493 SEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSA 552
E R T P S+S + S +++ S S+ T ST Q+A
Sbjct: 2974 --------EPRVPTSGTGDPRYASESMSYPDPSKASS--AMTSTSLASKLTTLFSTGQAA 3023
Query: 553 PQQQTSSSPPPPLLTPPPP--LQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKS 610
+ SSS P L T L P +S S T + P++ L + + +
Sbjct: 3024 --RSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNIL------VHLQTSA 3075
Query: 611 ILREPTFRWTSLKHSRSEPQYFSSAKYA--KEGLIRKPIFDNFRPPPLTPEDVGFASGFS 668
+ PT ++L S+ EP +S++ +EG + F P TP + S
Sbjct: 3076 LTLSPT---STLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSE-TPTSL---LPVS 3128
Query: 669 ASGTAASARLFSPLHSGTRFDMHKRSPLLRAPR---FTPSEAHSRIFE-SVTLPSNRTSA 724
+ + R SP + + ++ L+ T + S+ + + T P+
Sbjct: 3129 SPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEET 3188
Query: 725 GTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSS------------SELSPLTP 772
G+S +G S + I S + PS S RS +S + + P+T
Sbjct: 3189 GSSPAGTSPGSPEMSTTLKIMSS-KEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTL 3247
Query: 773 PSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTS----APAEPFS 828
S+ S S S+S L T +PT + P+ ++ + + P T+ P
Sbjct: 3248 QSTALGSGSTSISHLPTGTTSPTKS-PTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQ 3306
Query: 829 SSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVE---------------KDKS 873
S + +P +++ G + +PE +SK + S+ S
Sbjct: 3307 SLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSS 3366
Query: 874 RERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGR 933
+ N S +K K +E S+ P V K++ + TS S +A
Sbjct: 3367 NILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIP-STVLNNKIMAAEQQTSRSVDEAYSS 3425
Query: 934 KKS-SSHDSGTDIT-------SVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEK 985
S S SG+DIT + TL T+ +T L+ G+ T+L P+
Sbjct: 3426 TSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSL-TNPSGGKTSS 3484
Query: 986 EKTLCLSTPSSSTVKHSTSSIGSMLA 1011
++ + T++ + S++ S +A
Sbjct: 3485 ASSVTSPSIGLETLRANVSAVKSDIA 3510
Score = 39.7 bits (91), Expect = 0.060
Identities = 138/671 (20%), Positives = 254/671 (37%), Gaps = 100/671 (14%)
Query: 2898 SQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGE 2957
++ LP++ PV S SS+ + + +P L +T+ S T P + + L S + E
Sbjct: 10321 AESLPSSTPVPFS-SSTFTTTDSSTIPA-----LHEITSSSAT-PYRVDTSLGTESSTTE 10373
Query: 2958 KRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHG 3017
R+ + SS+ SP +D MT S G+V +
Sbjct: 10374 GRLVMVSTLDTSSQPGRTSSSPILDT----RMT--------------ESVELGTVTSAYQ 10415
Query: 3018 NNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEK 3077
TR + T G+ ++ +PN G + +T PA+ K
Sbjct: 10416 VPSLSTRLTRTDGIMEHITK---------IPNEAAHRGTIRPVKGPQTST----SPASPK 10462
Query: 3078 LIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNP 3137
+ + + T T ++ TS + T SV L P+ + + + +
Sbjct: 10463 GLHTGGTKR-METTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPT 10521
Query: 3138 SLP-TSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFP---PNISNPPSGLLI------G 3187
+ T+ +FP +P + S A T ++ P P++ N S G
Sbjct: 10522 EMMITTPYVFPD-----VPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSG 10576
Query: 3188 VQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSD 3247
+ P Q L SS+ ++ V P+ + +S+ T N + T S+ A S
Sbjct: 10577 AERSPVIQTLDVSSSEPDTTASWVIHPAETIPT--VSK--TTPNFFHSELDTVSSTATSH 10632
Query: 3248 V--VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIK-------RSKSSIMYFEP 3298
VS+ N +PS+L L+ + +TS+ T P + K R+ E
Sbjct: 10633 GADVSSAIPTNISPSELDALTPLVTISGTDTST--TFPTLTKSPHETETRTTWLTHPAET 10690
Query: 3299 APLLPQSVGGTAATAA-GTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSAS 3357
+ +P+++ + + T +I+ TS ++ + S ++V+ Q T++ T
Sbjct: 10691 SSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDR-- 10748
Query: 3358 VPGHVTLTNPRLLGTP-DIGSISNLLIKASQQSLGIQDQPVALPPS--SGMFPQLGTSQT 3414
+T P L +P + +I++L+ Q+ A+P S S +L TS
Sbjct: 10749 -----NMTIPTLTLSPGEPKTIASLVTHPEAQTSS------AIPTSTISPAVSRLVTSMV 10797
Query: 3415 PSTAAITAASSICVL-----PSTQTTGIT---AASPSGEADEHYQLQHVNQLLASKTGIH 3466
S AA T+ ++ + P+T + +T SP+ + S T H
Sbjct: 10798 TSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSH 10857
Query: 3467 SSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQA---SPTSPGGSPSSPSSGQ 3523
++ S++ P + T+ + +S+ + SP P +PS +S
Sbjct: 10858 GAE---SSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHG 10914
Query: 3524 RSASPSVPGPT 3534
AS ++P PT
Sbjct: 10915 EEASSAIPTPT 10925
Score = 39.3 bits (90), Expect = 0.079
Identities = 162/769 (21%), Positives = 261/769 (33%), Gaps = 129/769 (16%)
Query: 2904 TEPVDSSVSSSISAEEQFE---LPLELPSDLSVL---TTRSPTVP-SQNPSRLAVISDSG 2956
T P ++S + S E ++ +P+++ S + T P S P+ V
Sbjct: 163 TVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHT 222
Query: 2957 EKRVTITEKSVASSESDPALLSPGVDPTPEGHMT--------------PDHFIQGHMDAD 3002
R + ++ SS D LSP P G + P+ GH
Sbjct: 223 PGRTNPSFGTLYSSFLD---LSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRIS 279
Query: 3003 HISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNA 3062
+S P S N T S L P+SP VP +PNS P +SNA
Sbjct: 280 --TSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSA-IPFSMTLSNA 336
Query: 3063 AVQTTPPHLKPATEKL----IVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETN 3118
+T+ ++ L I Q + + T + ST
Sbjct: 337 --ETSAERVRSTISSLGTPSISTKQTAETILTFHAFAE--------TMDIPSTHIAKTLA 386
Query: 3119 TSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNIS 3178
+ LG G T G TS S + S +S + H + ++ N S
Sbjct: 387 SEWLGSPG-----TLG-----GTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTS 436
Query: 3179 NPPSGLLIGVQPPPDPQLLVS--ESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAP 3236
P L P + ++ + + T L + + +PS P L+T +
Sbjct: 437 MTP---LETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQ 493
Query: 3237 SSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYF 3296
SS+ + SD++ T S S +T+ + P + ++S
Sbjct: 494 SSSTAAHGSSDILRATTSSTSKASSWT---------SESTAQQFSEPQHTQWVETSPSMK 544
Query: 3297 EPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSA 3356
P SV T+ S +S T+ TS + +S ++ T T
Sbjct: 545 TERPPASTSVAAPITTSV-PSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQF 603
Query: 3357 SVPGHVTLTNPRLLGTPDIGS--ISNLLIKASQQS-------LGIQDQPVALPP-----S 3402
+VP +++T G+ GS ++LL +A+ S L PV++ P +
Sbjct: 604 AVPTGISMTG----GSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTA 659
Query: 3403 SGMFPQLGT--SQTPSTAAITAASSI--CVLPSTQTTGITA-------ASPSGEADEHYQ 3451
+G P GT S T ++ I SS+ + G+T +SP ++ H +
Sbjct: 660 AGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTK 719
Query: 3452 LQHVNQLL-----------ASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKA 3500
+ LL A+ T H + P++S T+ A S N A
Sbjct: 720 ISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAA 779
Query: 3501 LSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHL 3560
S + TSP PS SG+ +A + T + D N H L
Sbjct: 780 TSPERVRNATSPLTHPS--PSGEETAGSVLTLSTSAE--------TTDSPN--IHPTGTL 827
Query: 3561 RTSSSEA----HIPDQETTSLTSGTGTP-------GAEAEQQDTASVEQ 3598
+ SSE+ +P T + TP G E E+ SV Q
Sbjct: 828 TSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQ 876
Score = 38.9 bits (89), Expect = 0.10
Identities = 72/343 (20%), Positives = 144/343 (41%), Gaps = 64/343 (18%)
Query: 2076 PPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCY 2135
PP+ +T + + + P + S+ + S T +++ + HS+ + +
Sbjct: 4670 PPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVT----EGFAHSKITTAMN 4725
Query: 2136 YHV--ISKV-PRIRTPSYSPTQRSPGC-RPLPSAGSPTPTTHEI---VTVGDPLLSSGLR 2188
V +S+ P + + SP+ ++P LPS+ + TP H V++ L SS ++
Sbjct: 4726 NDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVK 4785
Query: 2189 SIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLG 2248
+ G S +++ SP NT +V+S +T TD+E++ ++ V+
Sbjct: 4786 TAGKVDTSLETVTS--------SPQSMSNTLDDISVTSAAT----TDIETTHPSINTVVT 4833
Query: 2249 PLNSSTSLGQNTST-SSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEK 2307
+ ++ S ++ ST S+ + + VT N ++S M+ ++ S + KSS +
Sbjct: 4834 NVGTTGSAFESHSTVSAYPEPSKVTSPN-------VTTSTMEDTTISRSIPKSSKTTRTE 4886
Query: 2308 TKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTT-SRELNVSKIGSFAEPSSVSFSSKEALS 2366
T+ SS L P++ T+ S+E+ SS E +
Sbjct: 4887 TETTSS-----------------LTPKLRETSISQEIT---------------SSTETST 4914
Query: 2367 FPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSN 2409
P+ L G + + ++ S+ S P D +L +S +N
Sbjct: 4915 VPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETN 4957
Score = 38.9 bits (89), Expect = 0.10
Identities = 97/413 (23%), Positives = 159/413 (38%), Gaps = 54/413 (13%)
Query: 437 PIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPS-VDTSTDSQASEE 495
P IA L + P ++ S+ S+ + + +S ++S ++++S+ + T++ + +
Sbjct: 10762 PKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATT 10821
Query: 496 IQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLST------- 548
+ ++ +P V P S ++S+ S S S + T +ST
Sbjct: 10822 VSLVTHPAQTSPTV--PWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVT 10879
Query: 549 -LQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMP--PTIPLASPFLPASTAPMQ 605
L ++ + S++ P L+P P S + H PT P SP +P +
Sbjct: 10880 PLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPT-PTVSPGVPGVVTSLV 10938
Query: 606 GKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFAS 665
+++ L S EP+ S + + P + PE G +
Sbjct: 10939 TSSRAVTSTTI---PILTFSLGEPETTPSMATSHGTEAGSAV------PTVLPEVPGMVT 10989
Query: 666 GFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFE--------SVTL 717
AS A ++ L SP P TPS A S E S +
Sbjct: 10990 SLVASSRAVTSTTLPTL---------TLSP--GEPETTPSMATSHGAEASSTVPTVSPEV 11038
Query: 718 PSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVS 777
P TS TSSSGV++ + SP E + SM T G +E S P +VS
Sbjct: 11039 PGVVTSLVTSSSGVNSTSIPTLILSPGELE---TTPSMATSHG----AEASSAVPTPTVS 11091
Query: 778 SSLSISVSPLATSALNPT-FTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSS 829
+S V+PL TS+ T T P +L+ S+E P TS E S+
Sbjct: 11092 PGVSGVVTPLVTSSRAVTSTTIPILTLS----SSEPETTPSMATSHGVEASSA 11140
Score = 37.4 bits (85), Expect = 0.30
Identities = 111/507 (21%), Positives = 195/507 (38%), Gaps = 51/507 (10%)
Query: 360 IIPSSKRT-DATIAKQ----LLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVV 414
+IP + +T DAT +Q L A+ + EKE + + + ++ + + V
Sbjct: 3838 VIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEV 3897
Query: 415 SAISS--RIIKTPRRFIEDEDYDPPI-------KIARLESTPNSRFSAPSCGSSEKSS-- 463
++ SS R + T +E P +IA EST + PS + E +
Sbjct: 3898 TSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWV 3957
Query: 464 AASQHSSQMS----SDSSRSSSPSVDTSTDSQA--SEEIQVLPEERSDTPEVHPPLPISQ 517
+S+H+S + S SS+ +SP V TST QA S PE E + L I
Sbjct: 3958 TSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIEL 4017
Query: 518 SPENESNDRRSRRYSVSERSFGSRT-TKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPAS 576
+ D S + S GS TK T ++ ++ +SS + + P + +
Sbjct: 4018 RDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAIT 4077
Query: 577 SISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAK 636
+S+ + LA P + ++ T WT + ++ +S
Sbjct: 4078 RLSNFPAMTESGGMILAMQTSPPGATSLSA--PTLDTSATASWTGTPLATTQRFTYSE-- 4133
Query: 637 YAKEGLIRKPIFDNFRPPPLTPEDVGFASG---FSASGTAASARLFSPLHSGTRFDMHKR 693
K L K D +P P + E+ +S A+ + ++ L S HS +
Sbjct: 4134 --KTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTS 4191
Query: 694 SPLLRAPRFTPSEAHSRIF--ESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSP 751
L + SRI +LP N +S T+ +S + R + ++
Sbjct: 4192 VFLSETSGLGKTTDMSRISLEPGTSLPPNLSS--TAGEALSTYEASR--------DTKAI 4241
Query: 752 SHSMRTRSGRL--SSSELSPL---TPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQS 806
HS T + +SSE SP+ T PS +S L S + + T F S T+
Sbjct: 4242 HHSADTAVTNMEATSSEYSPIPGHTKPSKATSPL--VTSHIMGDITSSTSVFGSSETTEI 4299
Query: 807 GESAEKNQRPRKQTSAPAEPFSSSSPT 833
+ NQ ++++++ ++ + T
Sbjct: 4300 ETVSSVNQGLQERSTSQVASSATETST 4326
Score = 36.6 bits (83), Expect = 0.51
Identities = 93/518 (17%), Positives = 186/518 (35%), Gaps = 59/518 (11%)
Query: 452 SAPSCGSSEK----SSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTP 507
SAP S+ SS S+ +++ +DSS+ SSP ++T ++ S ++ E S
Sbjct: 1687 SAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGS--- 1743
Query: 508 EVHPPLPISQSPENESND---------RRSRRYSVSERSFGS-RTTKKLSTLQSAPQQQT 557
++ +P++ SP + + S+ S S RT +TL S T
Sbjct: 1744 QMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGST 1803
Query: 558 SSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTF 617
++ L T L + + TPW+ L S AP T
Sbjct: 1804 ENTGKEKLRTASMDLPSPTPSMEVTPWIS----------LTLSNAP-----------NTT 1842
Query: 618 RWTSLKHS--RSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAAS 675
L H S ++ + G+ R +N +G ++ S + T S
Sbjct: 1843 DSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKS 1902
Query: 676 ARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRK 735
+ S +H L + + + + F S+ + ++ TS +++
Sbjct: 1903 -EVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINS-- 1959
Query: 736 RKRKVFSPIRSEPRSPSHSMRTRSGRL----------SSSELSPLTPPSSVSSSLSISVS 785
+P+ P +P + T +G + SS ++S T + +S+++S S
Sbjct: 1960 ------APMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSAS 2013
Query: 786 PLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT 845
P ++++ + S + S ES + R ++ ++S PT +P +
Sbjct: 2014 PTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEAL 2073
Query: 846 ERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSAL 905
G + P + + + +++R+ E E + + + + +
Sbjct: 2074 SSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSE 2133
Query: 906 YPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGT 943
PVG +V TS S + +++ GT
Sbjct: 2134 TPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGT 2171
Score = 36.2 bits (82), Expect = 0.67
Identities = 68/270 (25%), Positives = 104/270 (38%), Gaps = 63/270 (23%)
Query: 2187 LRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHV 2246
+R + + STS SP+ M T T + +++ TT AT S
Sbjct: 10446 IRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGT 10505
Query: 2247 LGPLNSS------------------------------TSLGQNTSTSSNLQRTVVTVGNK 2276
L PLN+S TSLG TST+ L RT +V N+
Sbjct: 10506 LTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTA--LPRTTPSVFNR 10563
Query: 2277 NSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSE--GSAHNVAYPG--IPKLA 2332
S + + LVS+S + + + L SSE +A V +P IP ++
Sbjct: 10564 ES------------ETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVS 10611
Query: 2333 PQVHNTTSRELN-VSKIG-------SFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTD 2384
N EL+ VS S A P+++S S +AL+ P + + G T
Sbjct: 10612 KTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALT-PLVTISG------TDTS 10664
Query: 2385 STQSANSSPDEDTEVKTLKLSGMSNRSSII 2414
+T + +TE +T L+ + SS I
Sbjct: 10665 TTFPTLTKSPHETETRTTWLTHPAETSSTI 10694
Score = 36.2 bits (82), Expect = 0.67
Identities = 64/298 (21%), Positives = 116/298 (38%), Gaps = 52/298 (17%)
Query: 2077 PVVEPDINSTVEHDENRTIAHSPTSFTESS----SKESQNTAEIISPPSPDRPPHSQ--- 2129
P V PD+ T A + T+ ++ ++ES+ TA ++S +R P Q
Sbjct: 10528 PYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLD 10587
Query: 2130 -------TSGSCYYHVISKVPRI--RTPSY--------SPTQRSPGCRPLPSAGSPTPTT 2172
T+ S H +P + TP++ S T S G S+ PT +
Sbjct: 10588 VSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGAD--VSSAIPTNIS 10645
Query: 2173 HEIVTVGDPLLS-SGLRSIGSRRHSTSSLSPQRSKLR---IMSPMRTGNT-------YSR 2221
+ PL++ SG + S T + SP ++ R + P T +T +S
Sbjct: 10646 PSELDALTPLVTISGTDT--STTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSH 10703
Query: 2222 NNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTV----------V 2271
+ + + T+ E+S+ + + P Q TS+ ++ T+
Sbjct: 10704 HESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPK 10763
Query: 2272 TVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIP 2329
T+ + +H + +SS + S+ S VS+ L L++K+S + PG P
Sbjct: 10764 TIASLVTHPEAQTSSAIPTSTISPAVSR---LVTSMVTSLAAKTSTTNRALTNSPGEP 10818
Score = 35.0 bits (79), Expect = 1.5
Identities = 131/615 (21%), Positives = 214/615 (34%), Gaps = 109/615 (17%)
Query: 458 SSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQ 517
SS +S S +S D S ++ + TS S EI + T + P SQ
Sbjct: 4934 SSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITI-------TTQTGPHGATSQ 4986
Query: 518 SPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASS 577
+ + + + ++TL S Q S + PP + P SS
Sbjct: 4987 DTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSS 5046
Query: 578 ISDHTPWLMPPTIP---LASPFLPASTAPMQGKRKSILRE---------PTFRWTS---- 621
+ TP L+ T+P L+SP T+ + K ILR P F TS
Sbjct: 5047 PAMTTPSLISSTLPEDKLSSPMTSLLTSGLV-KITDILRTRLEPVTSSLPNFSSTSDKIL 5105
Query: 622 --LKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAA---SA 676
K S+ + F S + + P L + A+ T +
Sbjct: 5106 ATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAP 5165
Query: 677 RLFSPLHSGTRFDMHKRSP---LLRAPRFTPSEAHSRIFESVTLPSNRTSAGT----SSS 729
P+H + KR P L R T + S + ++ GT SS+
Sbjct: 5166 STSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSST 5225
Query: 730 GVSNRKRKRKVFSPIRSE------------PRSPSHSMRTRSGRLS-SSELSPLTPPSSV 776
GV++ K+ +P + PR + S++T+S ++ +++ SP P S+
Sbjct: 5226 GVNS---SSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASP--PESAS 5280
Query: 777 SSSLSISVS-PLATSALNPTFT--FPSHSLTQ-----SGESAEKNQRPRKQTSAPAEPFS 828
S+L + S L+ + T T FP +T G + P ++TS+ + S
Sbjct: 5281 HSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMS 5340
Query: 829 S------------------SSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEK 870
S SSP P+ T T +PE ++ S+
Sbjct: 5341 SPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSI-- 5398
Query: 871 DKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKA 930
ER K + E S +++A+ VG V S KA
Sbjct: 5399 ------THERPATYKDTAHTEAAMHHS---TNTAVTNVGTSGSGHKSQSSVLADSETSKA 5449
Query: 931 TGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTN-LDLGPTAPSLEKEKTL 989
T ++S TLGDT+ + N+ +TN + PTA + +
Sbjct: 5450 TPLMSTTS----------TLGDTS-------VSTSTPNISQTNQIQTEPTASLSPRLRES 5492
Query: 990 CLSTPSSSTVKHSTS 1004
S +SST + +T+
Sbjct: 5493 STSEKTSSTTETNTA 5507
Score = 35.0 bits (79), Expect = 1.5
Identities = 72/333 (21%), Positives = 123/333 (36%), Gaps = 45/333 (13%)
Query: 703 TPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSE-PRSPSHSMRTRSGR 761
T +E+ + T PS TS T + S K + K S + P S ++ +R
Sbjct: 7021 TMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPG 7080
Query: 762 LSSSELSP-LTPPSSVSSSLS-----------------ISVSPLATSALNPTFTFPSHSL 803
S + SP L PSS+ S LS IS SPL ++L + + +
Sbjct: 7081 DMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDM 7140
Query: 804 TQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRD 863
+ P TS+P + +S T G T + + + +
Sbjct: 7141 LHTS--------PELVTSSPPKLSHTSDER-----LTTGKDTTNTEAVHPSTNTAASNVE 7187
Query: 864 ADKS-VEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVA 922
S E S D E K ++ + S+ R+ K E ++
Sbjct: 7188 IPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQK-----ESIS 7242
Query: 923 TSSSAKKATGR--KKSSSHDSGTDITSVTLGDTTAVKTKILIKKGR----GNLEKTNL-D 975
+ S + TG + SS+ ++ ++ V++G TT + + R G+ E T L +
Sbjct: 7243 SLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPE 7302
Query: 976 LGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
+ T ++ + L+ S T+K TS GS
Sbjct: 7303 ISTTRKIIKFPTSPILAESSEMTIKTQTSPPGS 7335
Score = 34.7 bits (78), Expect = 1.9
Identities = 53/266 (19%), Positives = 95/266 (35%), Gaps = 16/266 (6%)
Query: 742 SPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSH 801
SP + P P S ++ + S ++ L PS V ++ ++ SP T++ P + SH
Sbjct: 6808 SPAMTSP--PVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSH 6865
Query: 802 SLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT----ERGRNKDKAPEE 857
+ + E + TS A ++S GSQ+ + + K AP +
Sbjct: 6866 EILTTDEDTTAIEAMHPSTSTAATNVETTSS-------GHGSQSSVLADSEKTKATAPMD 6918
Query: 858 LSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVV 917
+ +V S + + K S ++ S Q++S V E
Sbjct: 6919 TTSTM-GHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPT 6977
Query: 918 GEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLG 977
G S + ++GR T + ++ T + + + T G
Sbjct: 6978 GTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPT--QTG 7035
Query: 978 PTAPSLEKEKTLCLSTPSSSTVKHST 1003
P+ + + TL ST S HST
Sbjct: 7036 PSGSTSQDTLTLDTSTTKSQAKTHST 7061
Score = 33.1 bits (74), Expect = 5.6
Identities = 105/533 (19%), Positives = 185/533 (34%), Gaps = 86/533 (16%)
Query: 2888 EKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELP--LELPSDLSVLTTRSPTVPSQN 2945
E+ G S TT+ + + ++++E E P L LPS V TT S + PS +
Sbjct: 800 EETAGSVLTLSTSAETTDSPNIHPTGTLTSESS-ESPSTLSLPSVSGVKTTFSSSTPSTH 858
Query: 2946 PSRLAVISDSGEKRVTITEKSVASSESD-------------PALLSPGVD--PTPEGHMT 2990
+ SGE+ + SV+ E+ P + P +D PT +
Sbjct: 859 ------LFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFS 912
Query: 2991 PDHFIQGHMDADHISSPPCGSVEQGHGN-----------------NQDLTRNSSTPGLQV 3033
H + + + SV G+ N+D +S+ P Q
Sbjct: 913 SSHLVS------ELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAP--QS 964
Query: 3034 PVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQT 3093
P + + +P++T + S S +A PAT + + +L T
Sbjct: 965 TTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTT 1024
Query: 3094 -LPNGVTQKIQLTSSVSS-----TPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFP 3147
NG ++++ T ++T+ +G T S S+ P
Sbjct: 1025 ETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSP 1084
Query: 3148 S----ASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQP------PPDPQLL 3197
S A+ P Q + +F I+ P G + P PP P
Sbjct: 1085 SQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD-- 1142
Query: 3198 VSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINF 3257
S++ T L ++PSS P T S+ + V+ +++
Sbjct: 1143 -PGSARSTWLGILSSSPSSP-----------------TPKVTMSSTFSTQRVTTSMIMDT 1184
Query: 3258 TPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTS 3317
+ N P+L SL S+ T I K + + PA L S GG +
Sbjct: 1185 VETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPE 1244
Query: 3318 TISQDTSHLTSGSVSGLASSSSV-LNVVSMQTTTTPTSSASVPGHVTLTNPRL 3369
+ + + HL + + S S+ + + V + TP + S+ H+ ++ R+
Sbjct: 1245 STNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARM 1297
Score = 32.7 bits (73), Expect = 7.4
Identities = 36/146 (24%), Positives = 58/146 (39%), Gaps = 13/146 (8%)
Query: 1254 PKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTG 1313
P S +EP R+ ++ ++S P S TT + ++ ++S A Q +T
Sbjct: 3126 PVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQA----AQGNSTW 3181
Query: 1314 PPRKEVPKTTPSEPKKKQPPPPESGPE----QSKQKKVAPRPSIPVKQKP-KEKEKPPPV 1368
P E T S P P PE SK+ ++P V+ P K E P+
Sbjct: 3182 PAPAE---ETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPM 3238
Query: 1369 NKQENAGTLNILSTLSNGNSSKQKIP 1394
TL + L +G++S +P
Sbjct: 3239 ETTVEPVTLQ-STALGSGSTSISHLP 3263
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 80.1 bits (196), Expect = 4e-14
Identities = 335/1683 (19%), Positives = 581/1683 (34%), Gaps = 236/1683 (14%)
Query: 2081 PDINSTVEHDENRTIAHSP-------TSFTESSSKES--QNTAEIISPPSPDRPPHSQTS 2131
PD + V E RT++ +P T+ TE++S + + T+ S PS P + T
Sbjct: 930 PDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTP 989
Query: 2132 GSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIG 2191
S H + T S +P + A SP PT E ++ S G +
Sbjct: 990 VS---HTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA-EGTSMPTSTPSEGSTPLT 1045
Query: 2192 SRRHSTSSLSPQRSKLRIMSPMRTGN---TYSRNNVSSVSTTGTATDLE----------- 2237
ST+ ++ + +P T TYS+ + SS + GT+
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105
Query: 2238 ---SSAKVVDHVLGPLNSS---TSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQS 2291
S+ VV L+++ TS+ TST ++ T + + ++ +
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM 1165
Query: 2292 SASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSF 2351
S + SS T + SK+ ++ + P + +T E +
Sbjct: 1166 PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP 1225
Query: 2352 AEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDT-EVKTLKLSGMSNR 2410
+ V+ S LS + D T T SA +S T E +L S S
Sbjct: 1226 VRHTPVASSEASTLSTSPV---------DTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG 1276
Query: 2411 SSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKP-EFMDEVL 2469
S+++ S++ + K + E T EG P E
Sbjct: 1277 STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR 1336
Query: 2470 TPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQV-----------EGSAKELQAPRKR 2518
TP + P N LS V + P+ EG++ P +
Sbjct: 1337 TP--LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG 1394
Query: 2519 TVKVTLTPLKM------ENESQSKNALKESSPASPLQIESTSPT--EPISA-SENPGDG- 2568
T +T P+ E + S + S+P + ++SPT E IS + P +G
Sbjct: 1395 TTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGK 1454
Query: 2569 -PVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPD-----GPKPQEDGSFKRRYPRRSAR 2622
P+ +NT +S+++ PV + ++ P P E S P +
Sbjct: 1455 TPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGST 1514
Query: 2623 ARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYY 2682
A +++ T + P +S+ + S+ + TS Y
Sbjct: 1515 ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST------Y 1568
Query: 2683 NFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPK 2742
+ T ++S L + + + + +D S T VTA+T SS
Sbjct: 1569 SEGSTPLTS-----LPVSTMLVVSSEANTLSTTPID-------SKTQVTASTEASSSTTA 1616
Query: 2743 RNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLS 2802
++ I P + S P+ S + T DS ++
Sbjct: 1617 EGS------SMTISTPSEGSPLLTSIPVSTTPVASPE------ASTLSTTPVDSNSPVIT 1664
Query: 2803 SLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQA 2862
S E S + TP++ + T + ++ + + + + +
Sbjct: 1665 STEVSS---SPTPAEGTSMPT------STYTEGRTPLTSITVRTTPVASSAISTLSTTPV 1715
Query: 2863 LGESPESSSSELLN---LGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEE 2919
+P ++S+E + EG + ++ + G + S + TT PV SS +S++SA
Sbjct: 1716 DNSTPVTTSTEARSSPTTSEGTSMPNSTPSE-GTTPLTSIPVSTT-PVLSSEASTLSATP 1773
Query: 2920 QFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKS---VASSESDPAL 2976
+ P S T SPT + +S+ G +T T S VA+SE+
Sbjct: 1774 ---IDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE-GMTPLTSTPVSHTLVANSEASTLS 1829
Query: 2977 LSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVS 3036
+P +P T +SS P + +G ST +PVS
Sbjct: 1830 TTPVDSNSPVVTSTA------------VSSSPTPA--EGTSIATSTPSEGSTALTSIPVS 1875
Query: 3037 PTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPN 3096
T ++ ++T + + ++ A ++ P + + +P L ++P
Sbjct: 1876 TTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP--PLTSIPV 1933
Query: 3097 GVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPM 3156
T + ST ++ +T T V + TT S+PT P+ S+G P+
Sbjct: 1934 STTTVASSEINTLST-TLADTRTPVTTYSQASSSPTTADGTSMPT-----PAYSEGSTPL 1987
Query: 3157 SHHQH----LHSFPAATQSSFPPNISNPPSGLLIGVQPPPDP---QLLVSESSQRTD--- 3206
+ + S A+T S+ P + S P + G P + S S+RT
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLA 2047
Query: 3207 ---LSTTVATPSSG--LKKRPI-SRLQTRKNKKLAPSSTPSNI-----APSDVVSNMTLI 3255
+STT+ S G L P+ S+ Q + + + S+T APS+ +T I
Sbjct: 2048 GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI 2107
Query: 3256 NFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAG 3315
+ + + + P L + S+ V + S S P P T T+
Sbjct: 2108 PLSTTPVAS-PEASTLSTTPVDSNSPVITSTEVSSS------PIP--------TEGTSMQ 2152
Query: 3316 TSTISQDTSHLTSGSVSGLASSSSVLNVVS---MQTTTTPTSSASVPGHVTLTNPRLL-- 3370
TST S + LTS VS +SS ++ +S + T+T T+S T + +
Sbjct: 2153 TSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT 2212
Query: 3371 GTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLP 3430
TP GS S+ + PV +S + + TP T + A SS
Sbjct: 2213 STPSEGS-------TPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE 2265
Query: 3431 STQ---------TTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVS 3481
T TT +T+ S H + + S T + S+ S
Sbjct: 2266 GTSIPTSTLSEGTTPLTSIPVS-----HTLVANSEVSTLSTTPVDSNTPFTTSTEASSPP 2320
Query: 3482 NFTQTVDAPNSMGLEQNKALS-----------------SAVQASPTSP-------GGSPS 3517
+ P S E N L+ S A ++P G SP+
Sbjct: 2321 PTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPT 2380
Query: 3518 SPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSL 3577
+ S G T P +P+ H + + TS+ + ++
Sbjct: 2381 TADDTSMPTSTYSEGST-PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPT 2439
Query: 3578 TS-GTGTPGAEAEQQDT--ASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKT 3634
T+ GT P + + T AS+ S+ AG ++ P T + + S+ P T
Sbjct: 2440 TAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTT 2499
Query: 3635 VEE 3637
E+
Sbjct: 2500 AED 2502
Score = 79.0 bits (193), Expect = 9e-14
Identities = 332/1650 (20%), Positives = 556/1650 (33%), Gaps = 323/1650 (19%)
Query: 2057 STTDARKRCVYTCKIVECRPPVVEPDINST-VEHDENRTIAHSP----TSFTESSSKESQ 2111
S T A + T E P+ +++T V E T++ +P T T S+ S
Sbjct: 2025 SPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084
Query: 2112 NTAE----IISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGS 2167
TAE IS PS P +++ +P TP SP + P+ S S
Sbjct: 2085 ATAEGSSMTISAPSEGSP------------LLTSIPLSTTPVASPEASTLSTTPVDS-NS 2131
Query: 2168 PTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSV 2227
P T+ E+ + P + ++ TS+ S +R+ L M P+ T S S++
Sbjct: 2132 PVITSTEVSSSPIPTEGTSMQ--------TSTYSDRRTPLTSM-PVSTTVVAS----SAI 2178
Query: 2228 STTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRT-------VVTVGNKNSHL 2280
ST T T +++S V + + +TS G + TS+ + + V T+ S
Sbjct: 2179 STLST-TPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEA 2237
Query: 2281 DGSSSSEMKQSS--ASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNT 2338
S++ + S+ + + SS E T + +S SEG+ + P V +T
Sbjct: 2238 STLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIP--------VSHT 2289
Query: 2339 TSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTE 2398
VS + + S+ F++ S P G ST S ++P
Sbjct: 2290 LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT-----SMPTSTSSEGNTPLTRMP 2344
Query: 2399 VKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEG 2458
V T ++ S +S ++ +S VTT +
Sbjct: 2345 VSTTMVA--SFETSTLSTTPADTSTP---------------------------VTTYSQA 2375
Query: 2459 NLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKR 2518
P D+ P S+ G L+ V P + E S
Sbjct: 2376 GSSPTTADDTSMP----------TSTYSEGSTPLTSVPVSTMPVVSSEAST------HST 2419
Query: 2519 TVKVTLTPLKMENESQSKNALKESSPASPLQIESTS-PTEPISASENPGDGPVAQPSPNN 2577
T T TP+ E+ S SP E TS PT P S G P+A +
Sbjct: 2420 TPVDTSTPVTTSTEASS----------SPTTAEGTSIPTSPPSE----GTTPLASMPVST 2465
Query: 2578 TSCQDSQSNNYQNLPVQDRNLMLPD-----GPKPQEDGSFKRRYPRRSARARSNMFFGLT 2632
T S++ PV M P ED P +A S +
Sbjct: 2466 TPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVV----PISTASEGSTLL---- 2517
Query: 2633 PLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSG 2692
IP ++ + VD + TS E ISS
Sbjct: 2518 ----------TSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTE------------ISSS 2555
Query: 2693 GEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTEN 2752
+ + P S S+ S +TT + IP E
Sbjct: 2556 ATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTE----- 2610
Query: 2753 LKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHT 2812
T SS + M + S V T L + + S +
Sbjct: 2611 ---------------TSSSPTTAKDTSMP-ISTPSEVSTSLTSILVSTMPVASSEASTLS 2654
Query: 2813 STPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSS 2872
+TP D L T +T S + G+ +P+ +P S+
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSPTTAE-----GSSMPTS-----------------TPGERST 2692
Query: 2873 ELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSV--SSSISAEEQFELPLELPSD 2930
L N+ L +N E + + + T+ PV +S SSS + E + + PSD
Sbjct: 2693 PLTNILVSTTLLANSEAST----LSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSD 2748
Query: 2931 LSVLTTRS--PTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGH 2988
S T T+P + V + + + + +T + ASS A ++ TP
Sbjct: 2749 GSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSET 2808
Query: 2989 MTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDL-TRNSSTPGLQVPVSPTVPIQNQKYV 3047
TP + + ++ P S E G + + T T + SPT V
Sbjct: 2809 STP-------LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT--AEGIVV 2859
Query: 3048 PNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSS 3107
P ST S G + +++ V TTP A+ L T P + + ++
Sbjct: 2860 PISTASEGSTLLTSIPVSTTPVASSEAS--------------TLSTTPVDTSIPVTTSTE 2905
Query: 3108 VSSTPSVME-TNTSVLGPMGGGLTLTTGLNPSLPTSQS----LFPSASKGLLPMSHHQHL 3162
SS+P+ E T+ + P LT+ L ++P + S L + P++
Sbjct: 2906 GSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEA 2965
Query: 3163 HSFPAATQS-----SFPPNISNPPSGLLIGVQP------------PPDPQLLVSESSQRT 3205
S P + S P P + + + P P D V+ S++ +
Sbjct: 2966 SSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEAS 3025
Query: 3206 DLSTT-------VATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFT 3258
TT ++TPS G P++ + P ++ + P D SN ++ T
Sbjct: 3026 SSPTTAEGTGIPISTPSEG--STPLTSIPVSTTPVAIPEASTLSTTPVD--SNSPVVTST 3081
Query: 3259 PSQLPNHPSLLDLGSLNTSSHRTVP------NIIKRSKSSIMYFEPAPLLPQSVGGTAAT 3312
P+ ++T S + P + + S+I P+ + T+
Sbjct: 3082 EVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTE 3141
Query: 3313 AAGTSTISQDTSHLTSGSVSG--------------LASSSSVLNVVSMQTTTTPTSSASV 3358
A + T S+ TS TS G ++S S L+ + T+T T+S
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201
Query: 3359 PGHVTLTNPRL-LGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPST 3417
T + TP G S+ + + PVA +S + S TP T
Sbjct: 3202 TSSTTAEGTSIPTSTPSEG-------MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254
Query: 3418 AAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASG 3477
+ A+SS P+ + T + ++PS + + +AS S D+++
Sbjct: 3255 TSTEASSS---PPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTST- 3310
Query: 3478 PQVSNFTQTVDAP--------------------NSMGLEQNKALSSAVQASPTSP-GGSP 3516
V+ ++Q +P +M +SS T+P S
Sbjct: 3311 -PVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTST 3369
Query: 3517 SSPSSGQRSASP------SVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIP 3570
+S + S SP S+P + + T +P+ +V+ L T+ +++
Sbjct: 3370 PVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSN-- 3427
Query: 3571 DQETTSLTSGTGTPGAEAEQQDTASVEQSS 3600
TTS + + AE T++ + S
Sbjct: 3428 TLVTTSTEASSSPTIAEGTSLPTSTTSEGS 3457
Score = 77.4 bits (189), Expect = 3e-13
Identities = 305/1453 (20%), Positives = 510/1453 (35%), Gaps = 221/1453 (15%)
Query: 2083 INSTVEHDENRTIAHSPTSFTESS---SKESQNTAEIISPPSPDRPPHSQTSGSCYYHVI 2139
+++++ + + SPT+ +S S S+ + + S P P S +G+ +
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPV 2835
Query: 2140 SKVPRIRTP---SYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIG----- 2191
+ T S SPT P+ +A + I P+ SS ++
Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVD 2895
Query: 2192 -------SRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVD 2244
S S+S + + + + I +P + VS+V G+ S+ V
Sbjct: 2896 TSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDT 2955
Query: 2245 HVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK 2304
P+ +S + +T+ + T G + + L S S M +S S+ + S +
Sbjct: 2956 RT--PVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS-SEASTLSRTPA 3012
Query: 2305 GEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIG-SFAEPSSVSF---- 2359
T V +S + S GIP P +T + VS + E S++S
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD 3072
Query: 2360 SSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMG 2419
S+ ++ + + ST S S+P V T ++ S S++ +
Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTS-SAISTLSTTPVD 3131
Query: 2420 SSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTP-EYMGQRP 2478
+S+ T E HSS TT E ++ E TP YM
Sbjct: 3132 TSTP----------VTTSTEAHSSP--------TTSEGTSMPTSTPSEGSTPLTYMPVST 3173
Query: 2479 CNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNA 2538
VSS+ D LS V + P+ +A T + T P +E +
Sbjct: 3174 MLVVSSE---DSTLSATPVDTSTPVTTS-----TEATSSTTAEGTSIPTSTPSEGMT--- 3222
Query: 2539 LKESSPASPLQIESTSPTEPISASENP--GDGPVAQPSPNNTSCQDSQSNNYQNLPVQDR 2596
P + + + +T P+++SE PV +P TS + S S
Sbjct: 3223 -----PLTSVPVSNT----PVASSEASILSTTPVDSNTPLTTSTEASSS----------- 3262
Query: 2597 NLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKR 2656
P E S P + ++M T + + P +S+
Sbjct: 3263 -------PPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTY 3315
Query: 2657 GKRSAEGQVDGADDLSTSDEDD----LYYYNFTRTVISSGGEERLASHNLFREEEQCDLP 2712
+ S+ + + TS + L +F+ T + S L++
Sbjct: 3316 SQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLST------------T 3363
Query: 2713 KISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSV 2772
+ V TE+ S++ TT + + IP + E T + V S V
Sbjct: 3364 PVDTSTPVTTSTEA--SLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTP-----VVSSEV 3416
Query: 2773 GHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSD 2832
+ +D+ V+ A+ +SL +S STP L T T + S+
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLST--TPVASSE 3474
Query: 2833 SDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMG 2892
+ ++ P D V ++P+ + + E +S GEG +N
Sbjct: 3475 ASTLSTT------PVDTSTPVTTSSPTNSS-PTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527
Query: 2893 LFEVFSQQLPTTEPVDSS--VSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLA 2950
+T PVDS+ V+SS A P+ L V T R T PS+ S L
Sbjct: 3528 PVASSEASTLSTTPVDSNTFVTSSSQASSS-------PATLQVTTMRMST-PSEGSSSLT 3579
Query: 2951 VISDSGEKRVTITEKSVASS----ESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISS 3006
+ S VT +E S S+ S P S + TP TP I M S
Sbjct: 3580 TMLLSSTY-VTSSEASTPSTPSVDRSTPVTTSTQSNSTP----TPPEVITLPMSTPSEVS 3634
Query: 3007 PPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQ--ISNAAV 3064
P + + +T + + +PV + P+ V +S +P + I +
Sbjct: 3635 TPLTIMPV---STTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSE 3691
Query: 3065 QTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSS--VSSTPSVMETNTSVL 3122
+TP P + + ++ L T P+ VT TS+ +SS+ ++ T SV
Sbjct: 3692 GSTPLTTMPVSTTRVTSSEGS----TLST-PSVVTSTPVTTSTEAISSSATLDSTTMSVS 3746
Query: 3123 GPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPS 3182
PM TT L + P ++ FP +S +P S + + A+ SS P + +
Sbjct: 3747 MPMEISTLGTTILVSTTPVTR--FPESSTPSIP-SVYTSMSMTTASEGSSSPTTLEGTTT 3803
Query: 3183 GLLIGVQPPPDPQLLVSESSQRTDLSTTVA-TPSSGLKKRPISRLQTRKNKKLAPSSTPS 3241
+ +S +S+R+ L TTV +P S + S L T P T +
Sbjct: 3804 -------------MPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTST 3850
Query: 3242 NIAPSDVVSNMTLINFT------------------PSQLPN---------HPSLLDLGSL 3274
+ + +T I + P+ P S S
Sbjct: 3851 KAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPST 3910
Query: 3275 NTSSHRTVPNIIKRSKSSI---------MYFEPAPLLPQSVGGTAATAAGTSTISQDTSH 3325
+T+S T+P S S I ++ P+ + AT ST ++
Sbjct: 3911 DTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTE 3970
Query: 3326 LTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP-GHVTLTN----PRLLGTPDIGSISN 3380
L + S S SSS+ + + + TTP + + P +VT++ PR S S
Sbjct: 3971 LNTPSTS---SSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAST 4027
Query: 3381 LLIKASQQ-SLGIQDQPVALPPSSGMFPQLGTSQT---------PSTAAITAASSICVLP 3430
L ++ S + +PV P S P TS T ST T+ASS V P
Sbjct: 4028 LSATSTPHTSTSVTTRPVT-PSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNP 4086
Query: 3431 STQTTGITAASPS 3443
TT T PS
Sbjct: 4087 EAVTTMTTRTKPS 4099
Score = 73.6 bits (179), Expect = 4e-12
Identities = 335/1640 (20%), Positives = 576/1640 (35%), Gaps = 275/1640 (16%)
Query: 2057 STTDARKRCVYTCKIVECRPPVVEPDINST-VEHDENRTIAHSP----TSFTESSSKESQ 2111
S T A + T + E P+ ++ T V + E T++ +P T FT S+ S
Sbjct: 2260 SPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSP 2319
Query: 2112 N-TAEIISPPSPD---------RPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRP 2161
TAE S P+ R P S T + + T S +P S
Sbjct: 2320 PPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASF--------ETSTLSTTPADTSTPVTT 2371
Query: 2162 LPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSR 2221
AGS +PTT + ++ S G ST S S + ++S +T+S
Sbjct: 2372 YSQAGS-SPTTADDTSMPTSTYSEG---------STPLTSVPVSTMPVVSS--EASTHST 2419
Query: 2222 NNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLD 2281
V + + T+T+ SS + P + + + T+ +++ + V + +
Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPS---EGTTPLASMPVSTTPVVSSEAGTL 2476
Query: 2282 GSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYP--GIPKLAPQVHNTT 2339
++ + + + SS E V S +SEGS + P P +P+ +
Sbjct: 2477 STTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLS 2536
Query: 2340 SRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEV 2399
+ ++ + + S S +S E S P ST S S+P V
Sbjct: 2537 TTPVDSNSPVVTSTEISSSATSAEGTSMP---------------TSTYSEGSTPLRSMPV 2581
Query: 2400 KTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGN 2459
T L+ S S++ + +S S T K+ +S P +V+T
Sbjct: 2582 STKPLAS-SEASTLSTTPVDTSIPVTTSTETSSSPTTAKD--TSMPISTPSEVSTSLTSI 2638
Query: 2460 LKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGV-PKAPPMQVEGSAKELQAPRKR 2518
L ++ + + +S+ + + L + P EGS+ P +R
Sbjct: 2639 L--------VSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER 2690
Query: 2519 TVKVT----LTPLKMENESQ--SKNALKESSPASPLQIESTSPTEPISAS---ENPGDG- 2568
+ +T T L +E+ S + S+P + S+SPT S P DG
Sbjct: 2691 STPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGS 2750
Query: 2569 -PVAQPSPNNTSCQDSQSNNYQNLPVQDR-----NLMLPDGPKPQEDGSFKRRYPRRSAR 2622
P+ + S+++ V + P E S P ++
Sbjct: 2751 TPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETST 2810
Query: 2623 ARSNMFFGLTPLYGVRSYGEEDIPFYSS-----STGKKRGKRSAEGQVDGADDLSTSDED 2677
++M TP+ + P +S ST +AEG V +ST+ E
Sbjct: 2811 PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVV---PISTASEG 2867
Query: 2678 DLYYYNF--TRTVISSGGEERLA------SHNLFREEEQCDLPKISQLDGVDDGTESDTS 2729
+ + T ++S L+ S + E P ++ + T S+ S
Sbjct: 2868 STLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS 2927
Query: 2730 VTATTRKSSQIPKRNGKENGTENLKIDR------------PEDAGEKEHVTKSSVGHKNE 2777
T+ S +P + + +D E + S+ G +
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987
Query: 2778 PKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNN 2837
P SVS + ++ + ++S V TST + + T + S +
Sbjct: 2988 PLTSM--SVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045
Query: 2838 SDDCG---NILPSDIMDF-VLKNTP--SMQALGESPESSSSELLNLGEGLGLDSNREKDM 2891
+ + P I + L TP S + S E SSS G + + + E
Sbjct: 3046 TPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGST 3105
Query: 2892 GLFEVFSQQLPTTE---------PVDSSVSSSISAE--------EQFELPLELPSDLSVL 2934
L V P T PVD+S + S E E +P PS+ S
Sbjct: 3106 PLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP 3165
Query: 2935 TTRSPT----VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMT 2990
T P V S S L+ VT + ++ +S+ ++ + TP MT
Sbjct: 3166 LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTS---TPSEGMT 3222
Query: 2991 PDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSS-TPGLQVPVSPTVPIQNQKYVPN 3049
P + + +S+ P S E + + N+ T + SP P +P
Sbjct: 3223 P-------LTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP--PTAEGTSMPT 3273
Query: 3050 STDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS 3109
ST S G + +++ V TT T+ + T + T + +
Sbjct: 3274 STPSEGSTPLTSMPVSTT-------------------------TVASSETSTLSTTPADT 3308
Query: 3110 STPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQH----LHSF 3165
STP + S P+ G S+PTS + S+G P+++ + S
Sbjct: 3309 STPVTTYSQASSSPPIADGT--------SMPTS-----TYSEGSTPLTNMSFSTTPVVSS 3355
Query: 3166 PAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSG---LKKRP 3222
A+T S+ P + S P + P +++ T + T+ +PS G L P
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSPT--------TAEGTSIPTS--SPSEGTTPLASMP 3405
Query: 3223 ISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTV 3282
+S ++ S+TP V + TL+ T ++ + P++ + SL TS+
Sbjct: 3406 VSTTPVVSSEVNTLSTTP--------VDSNTLVT-TSTEASSSPTIAEGTSLPTST---- 3452
Query: 3283 PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGT-STISQDTSHLTSGSVSGLASSSSVL 3341
S+ S P ++P S A++ A T ST DTS + S S SS +
Sbjct: 3453 -----TSEGST----PLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTS-SPTNSSPTTA 3502
Query: 3342 NVVSMQTTTTPTSSASVPGHVTLTNP------RLLGTPDIGSISNLLIKASQQSLGIQDQ 3395
V SM T+T S + T P L T + SN + +S Q+
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVD--SNTFVTSSSQA---SSS 3557
Query: 3396 PVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHV 3455
P L Q+ T + + + +++ + +L ST T A++PS + +
Sbjct: 3558 PATL--------QVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR------ 3603
Query: 3456 NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGL------EQNKALSSAVQASP 3509
T + +S + + + P+V + + S L + +S A AS
Sbjct: 3604 ------STPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAST 3657
Query: 3510 TSPGGSPSSPSSGQRSASPSVP-GPTKP-----KPKTKRFQLPLDKGNGKKHKVSHLRTS 3563
S +S Q S+SP P G T P + T +P+ + S L T
Sbjct: 3658 LPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTP 3717
Query: 3564 SSEAHIPDQETTSLTSGTGT 3583
S P +T S + T
Sbjct: 3718 SVVTSTPVTTSTEAISSSAT 3737
Score = 70.5 bits (171), Expect = 3e-11
Identities = 339/1791 (18%), Positives = 615/1791 (34%), Gaps = 269/1791 (15%)
Query: 2057 STTDARKRCVYTCKIVECRPPVVEPDINST-VEHDENRTIAHSPTS-----FTESSSKES 2110
S T A + T E R P+ + +T V T++ +P T + ++ S
Sbjct: 1671 SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSS 1730
Query: 2111 QNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSA----- 2165
T+E S P+ P T ++ +P TP S + P+ ++
Sbjct: 1731 PTTSEGTSMPN-STPSEGTTP-------LTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782
Query: 2166 ---GSPTPTTHEIVTVGDPLLSSGLRSIGSR----------RHSTSSLSPQRSKLRIMSP 2212
+ +PTT E ++ LS G+ + S ST S +P S SP
Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN----SP 1838
Query: 2213 MRTGNTYSRNNVSSVSTT-GTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVV 2271
+ T S + + T+ T+T E S + + ++S ST+ + T V
Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPV 1898
Query: 2272 T----VGNKNSHLDGSS--SSEMKQS--------------SASDLVSKSSSLKGEKTKVL 2311
T V + + DGSS +S ++ ++S++ + S++L +T V
Sbjct: 1899 TTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVT 1958
Query: 2312 SSKSSEGSAHNVAYPGIPKLAPQVHNT--TSRELNVSKIGSFAEPSSVSFSSKEALSFPH 2369
+ + S +P A +T TS L+ + + S +E S++S + + +
Sbjct: 1959 TYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVS-SEASTLSTTPVDTSTPAT 2017
Query: 2370 LHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKG 2429
G + S Q+ S+P E +T L+GM ++++ G++
Sbjct: 2018 TSTEGSSSPTTAGGTSIQT--STPSE----RTTPLAGMPVSTTLVVSSEGNTLSTTPVDS 2071
Query: 2430 KKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGD 2489
K T + SS + E +T P L+ + + +S+ +
Sbjct: 2072 KTQV--TNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDS 2129
Query: 2490 KGLSMPGVP-KAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSP---- 2544
+ + P+ EG++ + R +T P+ + S + ++P
Sbjct: 2130 NSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTS 2189
Query: 2545 ----------ASPLQIESTS-PTEPISASENP-------------GDGPVAQPSPNNTSC 2580
+SP E TS PT S P + +P +TS
Sbjct: 2190 TPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249
Query: 2581 QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMF-FGLTPLYGVRS 2639
+ S + P +P + + A S + TP+
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPV----- 2304
Query: 2640 YGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLAS 2699
+ + PF ++ST +AEG + STS E + TR +S+ +
Sbjct: 2305 --DSNTPF-TTSTEASSPPPTAEGT---SMPTSTSSEGNT---PLTRMPVSTTMVASFET 2355
Query: 2700 HNLFREEEQCDLPKISQLD-GVDDGTESDTSVTATTRKSSQIPKRN---------GKENG 2749
L P + G T DTS+ +T P + E
Sbjct: 2356 STLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAS 2415
Query: 2750 TENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSS----LE 2805
T + P D VT S+ + + + ++G L + S +
Sbjct: 2416 THSTT---PVDTSTP--VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVS 2470
Query: 2806 SSRRVHTSTPSDKNLLDTYNTELLKSDSDNNN-------SDDCGNILPSDIMDFVLKNTP 2858
S ++TP D + T +TE S + + + + +L S + +P
Sbjct: 2471 SEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASP 2530
Query: 2859 SMQALGESPESSSSELLNL---------GEGLGLDSN---------REKDMGLFEVFSQQ 2900
L +P S+S ++ EG + ++ R + + S +
Sbjct: 2531 EASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSE 2590
Query: 2901 LPT--TEPVDSSV--------SSSISAEEQFELPLELPSDLSVLTTRS--PTVPSQNPSR 2948
T T PVD+S+ SSS + + +P+ PS++S T T+P +
Sbjct: 2591 ASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEA 2650
Query: 2949 LAVISDSGEKRVTITEKSVASSESDPA------LLSPGVDPTPEGHMTPDHFIQGHMDAD 3002
+ + + R +T + SS A +PG TP ++ + + +A
Sbjct: 2651 STLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEAS 2710
Query: 3003 HISSPPCGS---------------VEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKY- 3046
+S+ P + +G + STP + VS T+P+ + +
Sbjct: 2711 TLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVS-TLPVASSEAS 2769
Query: 3047 ----------VPNSTDSPGPSQISNAAVQTTPPHLKPATEK-LIVVNQNMQPLY-----V 3090
+P +T + S + A V + P T L + N P+
Sbjct: 2770 TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829
Query: 3091 LQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSAS 3150
L T P + + ++ SS+P+ E + G TL T S+P S + S+
Sbjct: 2830 LSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLT----SIPVSTTPVASSE 2885
Query: 3151 KGLL---------PMSHHQHLHSFPAATQS-----SFPPNISNPPSGLLIGVQPPPDPQL 3196
L P++ S P + S P +S P + +L+ P
Sbjct: 2886 ASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP------ 2939
Query: 3197 LVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP---SDVVSNMT 3253
V+ S T +T V T + S T P STP S VS M
Sbjct: 2940 -VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMP 2998
Query: 3254 LINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATA 3313
+ + S L P+ D + T+S + + I P+ S G T T+
Sbjct: 2999 VASSEASTLSRTPA--DTSTPVTTSTEASSSPTTAEGTGI------PISTPSEGSTPLTS 3050
Query: 3314 AGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP------GHVTLTNP 3367
ST ++ S + + S+S V+ + ++ TP S+P G LT
Sbjct: 3051 IPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGV 3110
Query: 3368 RLLGTP----DIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAA 3423
+ TP I ++S + S + + S G T ST
Sbjct: 3111 PVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP 3170
Query: 3424 SSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSS--QRDLDSASGPQVS 3481
S ++ S++ + ++A + + A T I +S + + VS
Sbjct: 3171 VSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS 3230
Query: 3482 N---FTQTVDAPNSMGLEQNKALSSAVQAS---PTSPGGS-PSSPSSGQRSASPSVPGPT 3534
N + ++ ++ N L+++ +AS PT+ G S P+S S + S+P T
Sbjct: 3231 NTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVST 3290
Query: 3535 KPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTA 3594
++ L + ++ + SSS P + TS+ + T + G+
Sbjct: 3291 TTVASSETSTLSTTPADTSTPVTTYSQASSSP---PIADGTSMPTSTYSEGS----TPLT 3343
Query: 3595 SVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSP 3645
++ S+ A ++ P T + + S P T E SSP
Sbjct: 3344 NMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSP 3394
Score = 69.7 bits (169), Expect = 5e-11
Identities = 182/894 (20%), Positives = 303/894 (33%), Gaps = 101/894 (11%)
Query: 2707 EQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEH 2766
E P ++ + T S+ S T+ S P + + + +D K
Sbjct: 429 EASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVD------SKTQ 482
Query: 2767 VTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNT 2826
VT S+ + P + + ++G L + S ST S + DT
Sbjct: 483 VTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPV-DTSTP 541
Query: 2827 ELLKSDSDNNNSDDCGNILPSDIMD---FVLKNTPSMQALGESPESSSSELLNLGEGLGL 2883
S++ ++++ G +P+ L N P L S E+S++ +
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFV 601
Query: 2884 DSNREKDMGLFEVFSQQLPT-------TEPVDSSVSSSISAEEQFELPLELPSDLSVLTT 2936
++ E +PT T SVS+++ A + P D + T
Sbjct: 602 TTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661
Query: 2937 RSPTVPSQN--------PSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGH 2988
S S + P+ + + + VASSE+ +P TP
Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTT 721
Query: 2989 MTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVP 3048
T SS P + G STP +PVS T+ ++
Sbjct: 722 ST------------EASSSP--TTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTL 767
Query: 3049 NSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYV----------------LQ 3092
++T + I+ + + P T I PL L
Sbjct: 768 STTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLS 827
Query: 3093 TLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKG 3152
T P + ++ VSS+P+ E + G T T S+P S +L +++
Sbjct: 828 TTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLT----SMPVSTTLVATSAIS 883
Query: 3153 LL---------PMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ 3203
L P+++ S P ++ + P S P G + PD V S
Sbjct: 884 TLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-STPGEGST-PLTSMPDSTTPVVSSEA 941
Query: 3204 RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP---SDVVSNMTLINFTPS 3260
RT +T V T + + T P+STPS S VS+ + N S
Sbjct: 942 RTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEAS 1001
Query: 3261 QLPNHPSLLDLGS-LNTSSHRTVPNIIKRSKS---SIMYFEPAPLLPQSVGGTAATAAGT 3316
L P +D + L TS+ + P S S PL V T ++ T
Sbjct: 1002 TLSTTP--VDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059
Query: 3317 STIS---QDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTP 3373
ST+S DTS + + S +SSS+ + SM T+T S S P + RL+ +
Sbjct: 1060 STLSTTPADTSTPVT-TYSQASSSSTTADGTSMPTST--YSEGSTPLTSVPVSTRLVVSS 1116
Query: 3374 DIGSISNLLIKAS---QQSLGIQDQPVAL--------PPSSGMFPQLGTSQTPSTAAITA 3422
+ ++S + S S P PPS G P + P + +
Sbjct: 1117 EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP---LASMPVSTTLVV 1173
Query: 3423 ASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSN 3482
+S L +T T + S EA V + S G S+ V++
Sbjct: 1174 SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVAS 1233
Query: 3483 FTQTVDAPNSMGLEQNKALSSAVQASPTSPGGS--PSSPSSGQRSASPSVPGPT 3534
+ + + + S+ +SPT+ G+ P+S +S + S+P T
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVST 1287
Score = 68.6 bits (166), Expect = 1e-10
Identities = 171/795 (21%), Positives = 294/795 (36%), Gaps = 139/795 (17%)
Query: 2940 TVPSQNPSRLAVISDS---GEKRVTITE-KSVASSESDPALLSPGVDP------TPEGHM 2989
T P +V SD+ R+T TE ++ + S SD L P TPEG
Sbjct: 87 TNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTD 146
Query: 2990 TP-----DHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSS-TPGLQVPVSPTVPIQN 3043
P + I M +S+ P S E + ++ T Q SPT P
Sbjct: 147 VPMSTPSEESISSTMA--FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTP--E 202
Query: 3044 QKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQ 3103
+P ST+S G + +++ T +K A+ + I L T P ++ +
Sbjct: 203 STTIPKSTNSEGSTPLTSMPAST----MKVASSEAIT----------LLTTPVEISTPVT 248
Query: 3104 LTSSVSSTPSVME-TNTSVLGPMGGGLTLT-----------------------TGLNPSL 3139
+++ SS+P+ E + S P GG LT T +
Sbjct: 249 ISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVIT 308
Query: 3140 PTSQSLFPSASKGL-LPMSHHQH----LHSFPAATQ---SSFPPNISNPPSGLLIGVQPP 3191
T S P+ ++G +P S + L S PA+T +S +S P V
Sbjct: 309 STEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTS 368
Query: 3192 PDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSN 3251
+P L + + + L++T++ S+ L P+S + ++ S+ P V +
Sbjct: 369 TEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP--------VDS 420
Query: 3252 MTLINFTPSQLPNHPSLLDLGSLNTS--SHRTVP--------NIIKRSKSSIMYFEPAPL 3301
T + T S+ + P+ + S+ TS S + P + S++S + P
Sbjct: 421 KTFVT-TASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479
Query: 3302 LPQSVGGTAATAAG---------TSTISQDTSHLTSGSVSGL---ASSSSVLNVVSMQTT 3349
Q T A+++ TST S+ ++ LTS SVS + +S +S L+ + T+
Sbjct: 480 KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS 539
Query: 3350 TTPTSSASVPGHVTLTNPRLL--GTPDIGS-------ISNLLIKASQQSLGIQDQPVALP 3400
T T+S+ T + TP GS +S L+ +S+ S P
Sbjct: 540 TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAS-----TTSTTP 594
Query: 3401 PSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHV----- 3455
S F + + S+ S S + T IT+ S S + +
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 3456 --NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSP- 3512
N + + T SS + S P S +T+ SM + SS T+P
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMP-TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV 713
Query: 3513 GGSPSSPSSGQRSASP------SVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE 3566
S +S + S+SP S+P T + T +P+ K + S L T+
Sbjct: 714 DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTT--- 770
Query: 3567 AHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANE 3626
P +T +T+ T E + + + + P+ +L + V+ P
Sbjct: 771 ---PLDTSTHITTST-------EASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820
Query: 3627 QESAEPKTVEEEESN 3641
E++ T + ++
Sbjct: 821 PEASTLSTTPVDSNS 835
Score = 56.6 bits (135), Expect = 5e-07
Identities = 209/1016 (20%), Positives = 337/1016 (33%), Gaps = 143/1016 (14%)
Query: 440 IARLESTPNSRFSAPSCGSSEKSSA--ASQHSSQMSSDSSRSSSP--SVDTSTDSQASEE 495
I+ L +TP S P S+E S+ S+ +S +S S S+P S+ ST + E
Sbjct: 2178 ISTLSTTPVDT-STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSE 2236
Query: 496 IQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLS-----TLQ 550
L S TP V P++ S E S+ + S+ + TT S TL
Sbjct: 2237 ASTL----SATP-VDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLV 2291
Query: 551 SAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKS 610
+ + T S+ P TP ASS PT + P + P+ +
Sbjct: 2292 ANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVA 2351
Query: 611 ILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSAS 670
T T S Y + P T +D + +
Sbjct: 2352 SFETSTLSTTPADTSTPVTTYSQAGS-----------------SPTTADDTSMPTSTYSE 2394
Query: 671 GTA--ASARLFSPLHSGTRFDMHKRSPL-LRAPRFTPSEAHSR--IFESVTLPSNRTSAG 725
G+ S + + + H +P+ P T +EA S E ++P++ S G
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454
Query: 726 TS---SSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSE--------LSPLTPPS 774
T+ S VS + + P S M T + SS +S + S
Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGS 2514
Query: 775 SVSSSLSISVSPLATSALNPTFTFP---------SHSLTQSGESAEKNQRPRKQTSAPAE 825
++ +S+ +S +P+A+ + T P S ++ S SAE P S +
Sbjct: 2515 TLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST 2574
Query: 826 PFSSSSPTPLFPWFTPGSQTERGRNKDKA-PEELSKDRDADKSVEKDKSRERDREREKEN 884
P S P P + + T D + P S + + + KD S E
Sbjct: 2575 PLRSM-PVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVST 2633
Query: 885 KRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTD 944
S + PV + V T + +TG S + G+
Sbjct: 2634 SLTS------------ILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 945 ITSVTLGDTTAVKTKILIKKG-RGNLEKTNLDLGP----TAPSLEKEKTLCLSTPSSSTV 999
+ + T G+ + T IL+ N E + L P T + E + +T +++
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741
Query: 1000 KHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSS 1059
+ ST S GS P+T V S L A ++ + S + T P E+ SS
Sbjct: 2742 RISTPSDGS-------TPLTSILV-STLPVASSEASTV--STTAVDTSIPVTTSTEASSS 2791
Query: 1060 ETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGS 1119
T+ + P P+ ++ P L+SM + + +A S
Sbjct: 2792 PTTA------------------EVTSMPTSTPSETSTP-------LTSM-PVNHTPVASS 2825
Query: 1120 EDAEPLAPPIKPIKPVTRN-KAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPK 1178
E P+ PVT + KA P +G G + V T + +
Sbjct: 2826 EAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE 2885
Query: 1179 FGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKS--------KTSEKKDSKE 1230
+ + + + S + + + + S T S+
Sbjct: 2886 ASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA 2945
Query: 1231 SSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPP-------RKPVEEKSEEGNVSAPGPES 1283
S++ VD+ T SA +P + P R P+ S A S
Sbjct: 2946 STLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAS 3005
Query: 1284 KQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSE---PKKKQP--PPPESG 1338
+ TPA + S A P TG +P +TPSE P P P +
Sbjct: 3006 TLSRTPADTSTPVTTSTEASSSPTTAEGTG-----IPISTPSEGSTPLTSIPVSTTPVAI 3060
Query: 1339 PEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIP 1394
PE S + PV + P P GT +ST S G++ +P
Sbjct: 3061 PEASTLSTTPVDSNSPVVTSTEVSSSPTPAE-----GTSMPISTYSEGSTPLTGVP 3111
Score = 52.8 bits (125), Expect = 7e-06
Identities = 164/753 (21%), Positives = 256/753 (33%), Gaps = 104/753 (13%)
Query: 452 SAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHP 511
S PS GS+ +S + SS++S S+ VD+ T S E P T EV+
Sbjct: 445 STPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPP----TAEVNS 500
Query: 512 PLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPP 571
+P S +P S S S + +T + + ++ TSS TP
Sbjct: 501 -MPTS-TPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGT 558
Query: 572 LQPASSISD-HTPWLMPPT---IPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRS 627
P S+ S+ TP P + ++S ST P TF TS + S S
Sbjct: 559 SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN--------TFVTTSSEASSS 610
Query: 628 ----EPQYFSSAKYAKEG--------------------LIRKPIFDNFRPPPLTPEDVGF 663
E ++ Y++ G L P+ N P+T
Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSN---TPVTTSTEAT 667
Query: 664 ASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTS 723
+S +A GT+ ++ +PL P T A S T P + ++
Sbjct: 668 SSSTTAEGTSMPTSTYT----------EGSTPLTSMPVNTTLVASSEASTLSTTPVDTST 717
Query: 724 AGTSSSGVSNRKRKRKVFSPIRSEPR---SPSHSMRTRSGRLSSSELS-----PLTPPSS 775
T+S+ S+ S S P +P SM L+SSE S PL +
Sbjct: 718 PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTH 777
Query: 776 VSSSLSISVSPLATSALNPTFTFPSHS---LTQSGESAEKNQRPRKQT--SAPAEPFS-- 828
+++S S SP T + + PS LT S P T + P + S
Sbjct: 778 ITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPV 837
Query: 829 ------SSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREK 882
SSSPTP P S GR +S A ++ + D
Sbjct: 838 TTSTEVSSSPTPAEGTSMPTSTYSEGRT-PLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896
Query: 883 ENKRESRKE-KRKKGSEIQSSS-------------ALYPVGRVSKEKVVGEDVATSSSAK 928
N E+R +G+ + +S+ + PV + V TS+
Sbjct: 897 TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVT 956
Query: 929 KATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGR-GNLEKTNLDLGP----TAPSL 983
+T S + GT I + T + T T + N E + L P T +
Sbjct: 957 TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT 1016
Query: 984 EKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSL 1043
E + T +++ ST S GS ++P++ VAS + L S
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGS--TPLTRMPVSTTMVAS---SETSTLSTTPADTST 1071
Query: 1044 KQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREK 1103
T +A + + TS+ R V + TLS P +
Sbjct: 1072 PVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIP 1131
Query: 1104 ILSSMGNDDKSSIAGSEDAE-PLAPPIKPIKPV 1135
+ +S + SS +E P +PP + P+
Sbjct: 1132 VTTS--TEASSSPTTAEGTSIPTSPPSEGTTPL 1162
Score = 47.4 bits (111), Expect = 3e-04
Identities = 115/572 (20%), Positives = 197/572 (34%), Gaps = 48/572 (8%)
Query: 469 SSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSD-----------TP-EVHPPLPIS 516
S+Q SS + S ++ ST+S+ S + +P TP E+ P+ IS
Sbjct: 191 STQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS 250
Query: 517 QSPENESNDRRSRRYSVSERSFGSRTTKKLST---LQSAPQQQTSSSPPPPLLTPPPPLQ 573
+ S S S GS ++ L + + T S+ P P
Sbjct: 251 AQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310
Query: 574 PASSISDHTPWLMPPT-------IPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSR 626
ASS PT PL S PAST P+ S L ++L +
Sbjct: 311 EASSSPTTAEGTSIPTSTYTEGSTPLTST--PASTMPVATSEMSTLSITPVDTSTLVTTS 368
Query: 627 SEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGT 686
+EP + A ++ + + P P + AS T+ P+ S T
Sbjct: 369 TEPSSLPTTAEATS-MLTSTLSEGSTPLTNMPVSTILVASSEASTTSTI-----PVDSKT 422
Query: 687 RFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRS 746
+ S A S E T TS S++ V++ + +P+ S
Sbjct: 423 FVTTASEASSSPTTAEDTSIATSTPSEGST---PLTSMPVSTTPVASSEASNLSTTPVDS 479
Query: 747 EPRSPSHSMRTRSGRLSSSELSPLTPPSSVSS---SLSISVSPLATSALNPTFTFP---S 800
+ + + + + S + P + PS S+ S+S+S P+A+S + T P S
Sbjct: 480 KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS 539
Query: 801 HSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSK 860
+T S E++ + P + + P S+P P T + P
Sbjct: 540 TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP----A 595
Query: 861 DRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGED 920
D + + + S + E+ + + S+ L S D
Sbjct: 596 DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD 655
Query: 921 ----VATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDL 976
V TS+ A ++ + +S + T T + V T ++ L T +D
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715
Query: 977 GPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
T + E + +T +++ ST S GS
Sbjct: 716 S-TPVTTSTEASSSPTTADGASMPTSTPSEGS 746
Score = 46.6 bits (109), Expect = 5e-04
Identities = 146/683 (21%), Positives = 244/683 (35%), Gaps = 83/683 (12%)
Query: 413 VVSAISSRIIKTP----RRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQH 468
VVS+ ++ + TP + + P A + S P S P S+ +S +H
Sbjct: 1172 VVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS---TPGERSTPLTSMPVRH 1228
Query: 469 SSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRS 528
+ SS++S S+ VDTST S E P T LP S + E S
Sbjct: 1229 TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT-----SLPTSTTSEG------S 1277
Query: 529 RRYSVSERSFGSRTTKKLSTLQSAP---------QQQTSSSPPP------PLLTPPPPLQ 573
+ S T+ + STL + P + SSSP P P T
Sbjct: 1278 TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRT 1337
Query: 574 PASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFS 633
P +SI +T + I + S ++ P+ ++ T TS+ + S P +
Sbjct: 1338 PLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPN--SNPSEGT 1395
Query: 634 SAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKR 693
+ + + TP D SA T +S + T +
Sbjct: 1396 TPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEAT-SSPTTAEGISIPTSTPSEGK 1454
Query: 694 SPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSH 753
+PL P A+S T P + S +S+ VS+ SP +E S +
Sbjct: 1455 TPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSS--------SPTPAEGTSIAI 1506
Query: 754 SMRTR-SGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHS-LTQSGESAE 811
S + S L+S +S T SS +SL S +P TS T++ S S T G S +
Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSL--STTPAVTSTPVTTYSQASSSPTTADGTSMQ 1564
Query: 812 KNQRPRKQTSAPAEPFSS----SSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKS 867
+ T + P S+ SS S+T+ + + + ++ S
Sbjct: 1565 TSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTIS 1624
Query: 868 VEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSA 927
+ S S + + + S+S + + +V++S +
Sbjct: 1625 TPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV----------ITSTEVSSSPTP 1674
Query: 928 KKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEK 987
+ T S+ + T +TS+T+ T + I L T +D T + E
Sbjct: 1675 AEGTSMPTSTYTEGRTPLTSITVRTTPVASSAI------STLSTTPVD-NSTPVTTSTEA 1727
Query: 988 TLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVAS--LLKKAKAQLCKIEKSKSLKQ 1045
+T +++ +ST S G+ P+T V++ +L + L S +
Sbjct: 1728 RSSPTTSEGTSMPNSTPSEGT-------TPLTSIPVSTTPVLSSEASTL-----SATPID 1775
Query: 1046 TDQPKAQGQESDSSETSVRGPRI 1068
T P E+ SS T+ G I
Sbjct: 1776 TSTPVTTSTEATSSPTTAEGTSI 1798
Score = 46.2 bits (108), Expect = 6e-04
Identities = 106/439 (24%), Positives = 153/439 (34%), Gaps = 60/439 (13%)
Query: 452 SAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLP--EERSDTPEV 509
S P GS+ +S + +SS++ S+ VDTST S E P E + P
Sbjct: 917 STPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 976
Query: 510 HP---PLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLL 566
P P++ +P + + S ++S S T ST + SS PP
Sbjct: 977 TPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST-------EASSPPPTAEG 1029
Query: 567 TPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAP----------MQGKRKSILREPT 616
T P P+ + T + T+ +S ST P Q S + T
Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGT 1089
Query: 617 FRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPP-----PLTPEDVGFASGFSASG 671
TS S P +S + ++ P P+T +S +A G
Sbjct: 1090 SMPTSTYSEGSTP--LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG 1147
Query: 672 TAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGV 731
T+ SP GT +PL P T S T P + + +S+
Sbjct: 1148 TSIPT---SPPSEGT-------TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEA 1197
Query: 732 SNRKRKRKVFSPIRSEP---RSPSHSMRTRSGRLSSSE-----LSPLTPPSSVSSSLSIS 783
S+ +V S S P +P SM R ++SSE SP+ + V++S S
Sbjct: 1198 SSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETS 1257
Query: 784 VSPL---ATSALNPTFTFPSHSLTQSGESAEKNQRPRKQT--SAPAEPFS--------SS 830
SP TS T + S LT S P T + P + SS
Sbjct: 1258 SSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSS 1317
Query: 831 SPTPLFPWFTPGSQTERGR 849
SPTP P S GR
Sbjct: 1318 SPTPAEGTSMPTSTYSEGR 1336
Score = 46.2 bits (108), Expect = 6e-04
Identities = 119/627 (18%), Positives = 214/627 (34%), Gaps = 55/627 (8%)
Query: 400 KTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSRF------SA 453
+T + +I PV S+ S + TP ++ P S+P + S
Sbjct: 1689 RTPLTSITVRTTPVASSAISTLSTTPV-----DNSTPVTTSTEARSSPTTSEGTSMPNST 1743
Query: 454 PSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPL 513
PS G++ +S + +SS++S S+ +DTST S E P T L
Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTL 1803
Query: 514 -----PISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTP 568
P++ +P + + S ++S S + ST SSSP P T
Sbjct: 1804 SEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTST-------AVSSSPTPAEGTS 1856
Query: 569 PPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSE 628
P+ + T +IP+++ + +S ++ P + +
Sbjct: 1857 IATSTPSEGSTALT------SIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQV------ 1904
Query: 629 PQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRF 688
SS+ +G PPLT V + S+ S L T +
Sbjct: 1905 ----SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTY 1960
Query: 689 DMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEP 748
SP P+ A+S +T T+ SS + +P +
Sbjct: 1961 SQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTST 2020
Query: 749 RSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGE 808
S + +S S T P + + +S + + +S N T P S TQ
Sbjct: 2021 EGSSSPTTAGGTSIQTSTPSERTTP---LAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTN 2077
Query: 809 SAEKNQRPRKQ-----TSAPAE--PFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKD 861
S E + + SAP+E P +S P P +P + T D ++
Sbjct: 2078 STEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITST 2137
Query: 862 RDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDV 921
+ + + + + + R + + + +SSA+ + + V
Sbjct: 2138 EVSSSPIPTEGT---SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVD--TSTPV 2192
Query: 922 ATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAP 981
S+ A+ + + +S + T T + V T ++ L T +D T
Sbjct: 2193 TNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS-TPV 2251
Query: 982 SLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
+ E T +T +++ ST S G+
Sbjct: 2252 TTSTEATSSPTTAEGTSIPTSTLSEGT 2278
Score = 46.2 bits (108), Expect = 6e-04
Identities = 134/633 (21%), Positives = 231/633 (36%), Gaps = 86/633 (13%)
Query: 400 KTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIA-RLESTPNSR------FS 452
+T + ++ MPV S+ +S + +TP D P+ + S+P + S
Sbjct: 2986 RTPLTSMSVSTMPVASSEASTLSRTPA------DTSTPVTTSTEASSSPTTAEGTGIPIS 3039
Query: 453 APSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPP 512
PS GS+ +S + ++S S+ VD+++ S E+ P TP
Sbjct: 3040 TPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSP-----TPAEGTS 3094
Query: 513 LPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPL 572
+PIS E S + S T+ +STL + P ++ P
Sbjct: 3095 MPISTYSEG------STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTT 3148
Query: 573 QPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYF 632
+S+ TP + PL ++P ST + S L ++ + +E
Sbjct: 3149 SEGTSMPTSTP--SEGSTPLT--YMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSS 3204
Query: 633 SSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHK 692
++A EG + PLT V S + + AS +P+ S T
Sbjct: 3205 TTA----EGTSIPTSTPSEGMTPLTSVPV---SNTPVASSEASILSTTPVDSNT------ 3251
Query: 693 RSPLLRAPRFTPSEAHSR--IFESVTLPSNRTSAGTS---SSGVSNRKRKRKVFSPIRSE 747
P T +EA S E ++P++ S G++ S VS S + +
Sbjct: 3252 -------PLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTT 3304
Query: 748 PRSPSHSMRTRSGRLSSSELSPLT--PPSSVS------SSLSISVSPLATSALNPTFTFP 799
P S + T S SS ++ T P S+ S +++S S +P+ +S + T P
Sbjct: 3305 PADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364
Query: 800 SHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSP----TPLFPWFTPGSQTERGRNKDKAP 855
+ T S E + P T+A +SSP TPL P S T
Sbjct: 3365 VDTSTPVTTSTEASLSP---TTAEGTSIPTSSPSEGTTPLASM--PVSTTP--------- 3410
Query: 856 EELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEK 915
+S + + + D + E + + S S + +S
Sbjct: 3411 -VVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469
Query: 916 VVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLD 975
V + +T S+ T ++S + + S T + T++ T G G+ TN+
Sbjct: 3470 VASSEASTLSTTPVDTSTPVTTSSPTNS---SPTTAEVTSMPTSTA---GEGSTPLTNMP 3523
Query: 976 LGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGS 1008
+ T + + TL + S+T S+S S
Sbjct: 3524 VSTTPVASSEASTLSTTPVDSNTFVTSSSQASS 3556
Score = 46.2 bits (108), Expect = 6e-04
Identities = 106/472 (22%), Positives = 161/472 (34%), Gaps = 103/472 (21%)
Query: 401 TQVKNIRQFIMPVVSAISSRIIKTP---RRFIEDEDYDPPIKIARLESTPNSRFSAPSCG 457
T + N+ PV S+ +S + TP F+ A L+ T R S PS G
Sbjct: 3517 TPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS-QASSSPATLQVT-TMRMSTPSEG 3574
Query: 458 SSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQ 517
SS ++ + SS++S S+PSVD ST S + P TP LP+S
Sbjct: 3575 SSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTP-----TPPEVITLPMST 3629
Query: 518 SPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAP---------QQQTSSSPPPPLLTP 568
E S ++ S S T + T + P Q SSSP P T
Sbjct: 3630 PSE------VSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTT 3683
Query: 569 PPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSE 628
P P+ + PL + +P ST + S L P+ ++
Sbjct: 3684 MPIWTPSEG-----------STPLTT--MPVSTTRVTSSEGSTLSTPSVVTST------- 3723
Query: 629 PQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRF 688
P+T +S + T S + + +
Sbjct: 3724 --------------------------PVTTSTEAISSSATLDSTTMSVSMPMEISTLGTT 3757
Query: 689 DMHKRSPLLRAPR-FTPSEAHSRIFESVTLPSNRTSA-----GTSSSGVSNRKRKRKVFS 742
+ +P+ R P TPS S+T S +S+ GT++ +S + + +
Sbjct: 3758 ILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLT 3817
Query: 743 PIRSEPRSPSHSMRTRSGRLSSSELSPL-TPPSSVSSSLSISVSPLATSALNPTFTFPSH 801
+ P S +S SE S L TPP S +PL TS +F+ P+
Sbjct: 3818 TVLISPISV----------MSPSEASTLSTPPGDTS-------TPLLTSTKAGSFSIPAE 3860
Query: 802 SLTQSGESAEKNQRP--------RKQTSAPAEPFSSSSPTPLFPWFTPGSQT 845
T + P TS P +S+ P FTP + T
Sbjct: 3861 VTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT 3912
Score = 45.4 bits (106), Expect = 0.001
Identities = 101/413 (24%), Positives = 145/413 (35%), Gaps = 55/413 (13%)
Query: 452 SAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTD----SQASEEIQVLPEERSDTP 507
S PS GS+ +S ++ SS++S S+ DTST SQAS
Sbjct: 3274 STPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS------------ 3321
Query: 508 EVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLT 567
PP+ S + S + S + + STL + P ++ P +
Sbjct: 3322 ---PPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTST----PVTTS 3374
Query: 568 PPPPLQPASSISDHTPWLMPP--TIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHS 625
L P ++ P P T PLAS +P ST P+ + L +L +
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLAS--MPVSTTPVVSSEVNTLSTTPVDSNTLVTT 3432
Query: 626 RSEPQYFSSAKYAKEGLIRKPIFDNFRPPPL-------TPEDVGFASGFSAS--GTAASA 676
+E SS+ EG + PL TP AS S + T+
Sbjct: 3433 STEA---SSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPV 3489
Query: 677 RLFSPLHSG----------TRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGT 726
SP +S T +PL P T A S T P + + T
Sbjct: 3490 TTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVT 3549
Query: 727 SSSGVSNRKRKRKVFSPIRSEPRSPSHSMRT---RSGRLSSSELS-PLTPPSSVSSSLSI 782
SSS S+ +V + S P S S+ T S ++SSE S P TP SV S +
Sbjct: 3550 SSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTP--SVDRSTPV 3607
Query: 783 SVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPL 835
+ S + S P T S S P TS ++S P+
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPV 3660
Score = 44.3 bits (103), Expect = 0.002
Identities = 122/549 (22%), Positives = 193/549 (35%), Gaps = 77/549 (14%)
Query: 333 DKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAA 392
+ EG+ PLT + ++ + + P T TI+ Q + A
Sbjct: 211 NSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAP 270
Query: 393 QLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRR----FIEDEDYDPPIKIARLESTPN 448
T + + +M VVS+ +S + TP I + A S P
Sbjct: 271 S----GGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPT 326
Query: 449 SRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPE------- 501
S ++ GS+ +S + +S+ S S VDTST S E LP
Sbjct: 327 STYTE---GSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSM 383
Query: 502 -----ERSDTPEVHPPLPISQSPENESN-------DRRSRRYSVSERSFGSRTTKKLSTL 549
TP + P+ +E++ D ++ + SE S T + S
Sbjct: 384 LTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443
Query: 550 QSAPQQQTSSSPPPPLLTPPPPLQPASSIS----DHTPWLMPPTIPLASPFLPASTAPMQ 605
S P + ++ P+ T P AS++S D + T +SP TA +
Sbjct: 444 TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSP----PTAEVN 499
Query: 606 GKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFAS 665
S E + TS+ S + P S A L P+ D P + E AS
Sbjct: 500 SMPTSTPSEGSTPLTSMSVS-TMPVASSEA----STLSTTPV-DTSTPVTTSSE----AS 549
Query: 666 GFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAG 725
S + S +P T PL P T S + T P++ +
Sbjct: 550 SSSTTPEGTSIPTSTPSEGST--------PLTNMPVSTRLVVSSEASTTSTTPADSNTFV 601
Query: 726 TSSSGVSNRKRKRKVFS---PIRSEPRSPSHSMRTRSGRLSSSELSPL--------TPPS 774
T+SS S+ + S SE + SM + ++SSE S L TP +
Sbjct: 602 TTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661
Query: 775 SVSSSLSISVSPLATSALNPTFTFPSHSLTQ---------SGESAEKNQRPRKQTSAPAE 825
+ + + S S + TS T+T S LT S E++ + P TS P
Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTP-VDTSTPVT 720
Query: 826 PFSSSSPTP 834
+ +S +P
Sbjct: 721 TSTEASSSP 729
Score = 40.8 bits (94), Expect = 0.027
Identities = 94/464 (20%), Positives = 171/464 (36%), Gaps = 56/464 (12%)
Query: 3193 DPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNM 3252
+P++ ESS +D +T + + R S T + L PSST +P+
Sbjct: 88 NPEMTSIESSVTSDTPGVSSTRMTPTESRTTSE-STSDSTTLFPSSTEDTSSPTTPEGTD 146
Query: 3253 TLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAAT 3312
++ TPS+ ++ + + S ++ + S PL + ++ T
Sbjct: 147 VPMS-TPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMS------TPLTTSTQASSSPT 199
Query: 3313 AAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLG- 3371
++TI + T+ + GS + +S + V S + T T+ + VT++
Sbjct: 200 TPESTTIPKSTN--SEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSP 257
Query: 3372 -TPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLP 3430
T + S+SN S S G P+ P S M + T ST AA++I V+
Sbjct: 258 TTAEGPSLSN-----SAPSGG--STPLTRMPLSVMLVVSSEASTLSTTP--AATNIPVIT 308
Query: 3431 STQTTGITAASPSGEADEHYQLQHVNQLL---ASKTGIHSSQRDLDSASGPQVSNFTQTV 3487
ST+ + + + L AS + +S+ S + S T
Sbjct: 309 STEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTS 368
Query: 3488 DAPNSMGL--EQNKALSSAVQASPTSPGGSPSSP---SSGQRSASPSVPGPTKPKPKTKR 3542
P+S+ E L+S + T P S +S + S + ++P +K
Sbjct: 369 TEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK------- 421
Query: 3543 FQLPLDKGNGKKHKVSHLRTSSSEAHIPDQ-ETTSLTSGTGTPGAEAEQQDTASVEQSSQ 3601
+ + T+S + P E TS+ + T + G+ S+ S+
Sbjct: 422 ---------------TFVTTASEASSSPTTAEDTSIATSTPSEGSTP----LTSMPVSTT 462
Query: 3602 KECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSP 3645
A ++ P TQ + + S+ P T E S+P
Sbjct: 463 PVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTP 506
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 79.7 bits (195), Expect = 5e-14
Identities = 83/297 (27%), Positives = 119/297 (40%), Gaps = 64/297 (21%)
Query: 1109 GNDDKSSIAGSEDAEPLAPPI-----KPIKPVTRNKAPQEP--------------PVKKG 1149
G D K + A+PL PP +P +P R AP P P
Sbjct: 224 GCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNR 283
Query: 1150 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQ 1209
R++R+CG C C DCG C C DKPKFGG N K+Q C+ R+C LQ+ + L
Sbjct: 284 RQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPS 339
Query: 1210 AKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAR-----EDPAPKKSSSE---- 1260
+ + S ++ + SS ++ + + KPT + R AP K +
Sbjct: 340 VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFV 399
Query: 1261 -PPPRKPVE--EKSEEGNVSAPGPESKQATTPASRKSSK-----------QVSQ------ 1300
PPP + + V PGP + A+T A + ++ QV Q
Sbjct: 400 LPPPGTDLVFLREGASSPVQVPGPVA--ASTEALLQEAQCSGLSWVVALPQVKQEKADTQ 457
Query: 1301 ----PALVIPPQPP-TTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ---KKVAP 1349
P + P G P K V PS K++PP PE E++K K+AP
Sbjct: 458 DEWTPGTAVLTSPVLVPGCPSKAVDPGLPS--VKQEPPDPEEDKEENKDDSASKLAP 512
Score = 47.8 bits (112), Expect = 2e-04
Identities = 33/115 (28%), Positives = 48/115 (41%), Gaps = 30/115 (26%)
Query: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
+SR CG C GCQ EDCG C CL P+ G L++Q
Sbjct: 172 KSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 206
Query: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK-PTPSAREDPAPKKSSSEPPPR 1264
K V+++ + K + +K +S + +Q P P + P P +EP PR
Sbjct: 207 KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPR 257
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 79.7 bits (195), Expect = 5e-14
Identities = 83/297 (27%), Positives = 119/297 (40%), Gaps = 64/297 (21%)
Query: 1109 GNDDKSSIAGSEDAEPLAPPI-----KPIKPVTRNKAPQEP--------------PVKKG 1149
G D K + A+PL PP +P +P R AP P P
Sbjct: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNR 332
Query: 1150 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQ 1209
R++R+CG C C DCG C C DKPKFGG N K+Q C+ R+C LQ+ + L
Sbjct: 333 RQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPS 388
Query: 1210 AKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAR-----EDPAPKKSSSE---- 1260
+ + S ++ + SS ++ + + KPT + R AP K +
Sbjct: 389 VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFV 448
Query: 1261 -PPPRKPVE--EKSEEGNVSAPGPESKQATTPASRKSSK-----------QVSQ------ 1300
PPP + + V PGP + A+T A + ++ QV Q
Sbjct: 449 LPPPGTDLVFLREGASSPVQVPGPVA--ASTEALLQEAQCSGLSWVVALPQVKQEKADTQ 506
Query: 1301 ----PALVIPPQPP-TTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ---KKVAP 1349
P + P G P K V PS K++PP PE E++K K+AP
Sbjct: 507 DEWTPGTAVLTSPVLVPGCPSKAVDPGLPS--VKQEPPDPEEDKEENKDDSASKLAP 561
Score = 48.9 bits (115), Expect = 1e-04
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 30/115 (26%)
Query: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
RSR CG C GCQ EDCG C CL P+ G L++Q
Sbjct: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255
Query: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK-PTPSAREDPAPKKSSSEPPPR 1264
K V+++ + K + +K +S + +Q P P + P P +EP PR
Sbjct: 256 KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPR 306
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 79.0 bits (193), Expect = 9e-14
Identities = 204/903 (22%), Positives = 324/903 (35%), Gaps = 139/903 (15%)
Query: 453 APSCGSSEKSSAASQ--HSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVH 510
APS S+K S+ Q HSSQ +S S S + S D ++ ++ H
Sbjct: 114 APSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEH 173
Query: 511 PPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPP 570
S+S S S RS G+ K + Q S SP P
Sbjct: 174 SK---SRSSSPGKPQAVSSLNSSHSRSHGNDHHSK--------EHQRSKSPRDPDANWDS 222
Query: 571 PLQPASSISDHTPWLMPPTIPLASPFL----PASTAPMQGKRKSILREPTFRWTSLKHSR 626
P + S H+ PP++ S + A PM G+ + + ++S H
Sbjct: 223 PSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN 282
Query: 627 SEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGT 686
S + S+K L + I P P D SASG S +
Sbjct: 283 SMTELKPSSK---AHLTKLKI-------PSQPLDA------SASGDV------SCVDEIL 320
Query: 687 RFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRS 746
+ H P L A TP + F T S +++ GT ++K ++P ++
Sbjct: 321 KEMTHSWPPPLTAIH-TPCKTEPSKFPFPTKESQQSNFGTG---------EQKRYNPSKT 370
Query: 747 EPRSPSHSMRTRSGRLSSSELSP------LTPPSSVSSSLSISVSPLATSALNPTFTFPS 800
S SM +LSSSE S T P S S S + A N S
Sbjct: 371 SNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSS 430
Query: 801 HSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSK 860
HS ++S ++ S EP S+SP P P T Q + NK P ++S
Sbjct: 431 HSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPP-TNKWQLDNWLNKVN-PHKVSP 488
Query: 861 DRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGED 920
D ++ + + KE + + S + +S+ P GR SK
Sbjct: 489 ASSVDSNIPSSQGYK------KEGREQGTGNSYTDTSGPKETSSATP-GRDSK------- 534
Query: 921 VATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKT-KILIKKGRGNLEKTNLDLGPT 979
++ GR+KS + T T+G K K ++ RG L+ +
Sbjct: 535 -TIQKGSESGRGRQKSPAQSDSTTQRR-TVGKKQPKKAEKAAAEEPRGGLKIES------ 586
Query: 980 APSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEK 1039
E L S PSS +H ++ GS K + R + KK K+ +K
Sbjct: 587 ----ETPVDLASSMPSS---RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
Query: 1040 SKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAA--VALGRKRAVFPDDMPTLSALP 1097
S+ + +TD + ES+S S + P+ R ++ + + F M + P
Sbjct: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFS----P 695
Query: 1098 WEEREKILSSMGNDDKSSIAGSEDAEPLAP-PIKPIKPVTRNKAPQEPPVKKGRRSRRCG 1156
EE+E + DD+ + D L P KP K EPP KG +
Sbjct: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-------EPP--KGEKK---- 742
Query: 1157 QCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKK 1216
VPE + + K + + + K ++ ++A K+ K K
Sbjct: 743 -----NVPE-----KHTREAQKQASEKVSNKGKRKHKNED----DNRASESKKPKTEDKN 788
Query: 1217 EKKSKTSEKKDSKESSVV--KNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEG 1274
K S ++S + S K+++ S P PS +DP + S + + KS
Sbjct: 789 SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPS--KDPKTEHGSRKRTISQSSSLKSSSN 846
Query: 1275 NVSAPGPESKQATTPASRK--------SSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSE 1326
+ SK +++ + +K SSK+V + A P + PP P S+
Sbjct: 847 SNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKA----PSSSSNCPP--SAPTLDSSK 900
Query: 1327 PKK 1329
P++
Sbjct: 901 PRR 903
Score = 45.4 bits (106), Expect = 0.001
Identities = 112/536 (20%), Positives = 190/536 (35%), Gaps = 95/536 (17%)
Query: 40 LPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSA 99
+P P P S A + ++ SG+ G+ + S SSSS S ++ S SA
Sbjct: 402 MPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSES-ESSSSDSEANEPSQSA 460
Query: 100 SSGPA------------LLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQ 147
S P L +V P + ++++ +N+ + G G G
Sbjct: 461 SPEPEPPPTNKWQLDNWLNKVNP---HKVSPASSVDSNIPSSQ---GYKKEGREQGTGNS 514
Query: 148 FLGFGSDEEVRVRSPTR-SPSVKTSPRKPRGRPRSGSDRNSAILSDPSVFSPLNKSETKS 206
+ +E +P R S +++ RGR + SP T
Sbjct: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQK----------------SPAQSDSTTQ 558
Query: 207 GDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDI-SELP--------KGNKEDSLKK-I 256
+ KK K EK P G+KI+ D+ S +P KG+++ ++KK
Sbjct: 559 RRTVGKKQPKKAEKAAAEEPR-GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
Query: 257 KRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPS 316
K +P T ++ KK ++ S KS+ ++ PPS++ K P
Sbjct: 618 KSSPRPTAEK----KKYKSTSKSSQKSR---EIIETDTSSSDSDESESLPPSSQTPKYPE 670
Query: 317 GLLINSELEKPQKVR--------------KDKEGTPPLT----------KEDKTVVRQSP 352
N KP V ++KE PL+ K D ++ + P
Sbjct: 671 S---NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIP 727
Query: 353 RRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKI----------EKEAAQLQGRKVKTQ 402
KP + K + ++ + A+K A +K+ E + + +K KT+
Sbjct: 728 G--KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTE 785
Query: 403 VKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDP-PIKIARLESTPNSRFSAPSCGSSEK 461
KN P + SS+ + + P P K + E R + S
Sbjct: 786 DKNSAGH-KPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSS 844
Query: 462 SSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQ 517
S++ + S + SS S + T S + E + P S+ P P L S+
Sbjct: 845 SNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
Score = 42.7 bits (99), Expect = 0.007
Identities = 131/595 (22%), Positives = 214/595 (35%), Gaps = 121/595 (20%)
Query: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKS-SAASQHSSQMSSDSSR-SSSPSVDTS 487
ED D + STP S S PS +SE + ++ SS S+SS S S S +S
Sbjct: 390 EDSDGEQDCDKTMPRSTPGSN-SEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSS 448
Query: 488 TDSQASEEIQVLPEERSDTPEVHP----------------PLPISQSPENESNDRRSRRY 531
+DS+A+E Q S +PE P P +S + +SN S+ Y
Sbjct: 449 SDSEANEPSQ------SASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGY 502
Query: 532 SVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLT-----------PPPPLQPASSISD 580
R G T T S P++ +S++P T P Q S+
Sbjct: 503 KKEGREQG---TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
Query: 581 HTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKE 640
T P A+ +G K P +S+ SR + ++ K +++
Sbjct: 560 RTVGKKQP-----KKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK----AATKGSRK 610
Query: 641 GLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAP 700
I+K + RP T E + S S S + + + S + P + P
Sbjct: 611 PNIKKESKSSPRP---TAEKKKYKS-TSKSSQKSREIIETDTSSSDSDESESLPPSSQTP 666
Query: 701 RFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSG 760
++ SNRT SS + ++++FSP+ +
Sbjct: 667 KYP--------------ESNRTPVKPSSVEEEDSFFRQRMFSPMEEK------------- 699
Query: 761 RLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQS-GESAEKNQRPRKQ 819
LSPL+ P L + + LN P ++ EK P K
Sbjct: 700 ----ELLSPLSEPDD-RYPLIVKID------LNLLTRIPGKPYKETEPPKGEKKNVPEKH 748
Query: 820 TSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDRE 879
T + S E+ NK K + D A +S +K K+ +++
Sbjct: 749 TREAQKQAS-----------------EKVSNKGKRKHKNEDDNRASES-KKPKTEDKNSA 790
Query: 880 REK-ENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGE------DVATSSSAKKATG 932
K + RES K+ K ++ S P G V + E ++ SSS K ++
Sbjct: 791 GHKPSSNRESSKQSAAKEKDLLPS----PAGPVPSKDPKTEHGSRKRTISQSSSLKSSSN 846
Query: 933 RKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEK 987
K +S S + +S + T KT K+ + ++ + P+AP+L+ K
Sbjct: 847 SNKETS-GSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
Score = 41.2 bits (95), Expect = 0.021
Identities = 78/334 (23%), Positives = 121/334 (36%), Gaps = 55/334 (16%)
Query: 2274 GNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAP 2333
G NS D SS S + SS SD S+SSS S+ A+ + P+ P
Sbjct: 420 GADNSRDDSSSHSGSESSSGSDSESESSS-------------SDSEANEPSQSASPEPEP 466
Query: 2334 QVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSP 2393
N + ++K+ P VS +S + P ++ R+Q T ++ + S P
Sbjct: 467 PPTNKWQLDNWLNKVN----PHKVSPASSVDSNIPSSQ-GYKKEGREQGTGNSYTDTSGP 521
Query: 2394 DEDTEV------KTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFL 2447
E + KT++ S R + S+ RR GKK K+ EK +++
Sbjct: 522 KETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKA--EKAAAE--- 576
Query: 2448 EPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEG 2507
EP G LK E V M S K KG P + K E
Sbjct: 577 EP-------RGGLKIESETPVDLASSMPS------SRHKAATKGSRKPNIKK------ES 617
Query: 2508 SAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGD 2567
+ K+ K T SQ + E+ +S ES S P S + +
Sbjct: 618 KSSPRPTAEKKKYKST------SKSSQKSREIIETDTSSSDSDESES-LPPSSQTPKYPE 670
Query: 2568 GPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLP 2601
P++ +DS P++++ L+ P
Sbjct: 671 SNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSP 704
Score = 38.1 bits (87), Expect = 0.18
Identities = 43/189 (22%), Positives = 70/189 (37%), Gaps = 18/189 (9%)
Query: 1220 SKTSEKKDSKESSVVKNVVDSS--------QKPTPSAREDPAPKKSSSEPPPR--KPVEE 1269
+K + K S SSV N+ S Q S + PK++SS P R K +++
Sbjct: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
Query: 1270 KSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
SE G P +TT KQ + +P E P S
Sbjct: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
Query: 1330 KQPPPPESG---PEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNG 1386
+ G P K+ K +PRP+ K+K K + Q++ + ++ S+
Sbjct: 599 SRHKAATKGSRKPNIKKESKSSPRPT-----AEKKKYKSTSKSSQKSREIIETDTSSSDS 653
Query: 1387 NSSKQKIPA 1395
+ S+ P+
Sbjct: 654 DESESLPPS 662
Score = 35.4 bits (80), Expect = 1.1
Identities = 52/241 (21%), Positives = 93/241 (38%), Gaps = 30/241 (12%)
Query: 3441 SPSGEADEHYQLQHV-NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNK 3499
+PS ++ H + + L S + ++D D NS G + ++
Sbjct: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSR 425
Query: 3500 ALSSAVQASPTSPGGSPSSPSSGQRSAS--PSVPGPTKPKPK-TKRFQLPLDKGNGKKHK 3556
SS+ S +S G S SS S + PS +P+P T ++QL HK
Sbjct: 426 DDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHK 485
Query: 3557 VSHLRTSSSEAHIPDQE---TTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV 3613
VS SS +++IP + GTG DT+ +++S G+ + +
Sbjct: 486 VS--PASSVDSNIPSSQGYKKEGREQGTGN-----SYTDTSGPKETSSATPGRDSKTIQK 538
Query: 3614 LPEV--QVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVF 3671
E ++PA + + +TV +++ K+ E ++P+ GL
Sbjct: 539 GSESGRGRQKSPAQSDSTTQRRTVG--------------KKQPKKAEKAAAEEPRGGLKI 584
Query: 3672 E 3672
E
Sbjct: 585 E 585
Score = 35.4 bits (80), Expect = 1.1
Identities = 62/296 (20%), Positives = 109/296 (36%), Gaps = 22/296 (7%)
Query: 2713 KISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAG-------EKE 2765
K+S + D + D ++ +T S+ P + E G +N + D +G + E
Sbjct: 385 KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSE-GADNSRDDSSSHSGSESSSGSDSE 443
Query: 2766 HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDT-- 2823
+ SS NEP T + L+ L+ + + +V ++ D N+ +
Sbjct: 444 SESSSSDSEANEPSQSASPEPEPPPTN-KWQLDNWLNKV-NPHKVSPASSVDSNIPSSQG 501
Query: 2824 YNTELLKSDSDNNNSDDCG-----NILPSDIMDFVLKNTPSMQALGESPESSSSELLNLG 2878
Y E + + N+ +D G + P + K + S + +SP S S
Sbjct: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
Query: 2879 EGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRS 2938
G EK ++ + PVD + S S + P+ ++S
Sbjct: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKK--ESKS 619
Query: 2939 PTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT---PEGHMTP 2991
P+ + S S +K I E +SS+SD + P T PE + TP
Sbjct: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTP 675
Score = 35.0 bits (79), Expect = 1.5
Identities = 99/533 (18%), Positives = 184/533 (34%), Gaps = 75/533 (14%)
Query: 2089 HDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTP 2148
H + + + S + SSS N + P P+ PP ++ + + ++ P +P
Sbjct: 431 HSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN--PHKVSP 488
Query: 2149 SYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLR 2208
+ S P + G T + P TSS +P R
Sbjct: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGP-------------KETSSATPGRDSKT 535
Query: 2209 IMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLG-------PLNSSTSLGQNTS 2261
I +G ++ S STT T + K + + S T + +S
Sbjct: 536 IQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
Query: 2262 TSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVL-----SSKSS 2316
S+ + T G++ ++ S S + +A KS+S +K++ + SS S
Sbjct: 596 MPSS-RHKAATKGSRKPNIKKESKSS-PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
Query: 2317 EGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQR 2376
+ S PK P+ + T + +V + SF S ++ L P +
Sbjct: 654 DESESLPPSSQTPKY-PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSP----LSEP 708
Query: 2377 NDR-----DQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK 2431
+DR + P ++TE + ++ +H +R+ +++ +
Sbjct: 709 DDRYPLIVKIDLNLLTRIPGKPYKETE------PPKGEKKNVPEKH----TREAQKQASE 758
Query: 2432 SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDK---IG 2488
K KH ++ + + KP+ D+ G +P +N S K
Sbjct: 759 KVSNKGKRKHKNEDDNRASE-------SKKPKTEDK----NSAGHKPSSNRESSKQSAAK 807
Query: 2489 DKGLSMPG----VPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSP 2544
+K L +P VP P GS RKRT+ + + N ++ + ++S
Sbjct: 808 EKDL-LPSPAGPVPSKDPKTEHGS-------RKRTISQSSSLKSSSNSNKETSGSSKNSS 859
Query: 2545 ASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRN 2597
++ Q ++ T S + P + DS L DRN
Sbjct: 860 STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRN 912
Score = 33.1 bits (74), Expect = 5.6
Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 23/172 (13%)
Query: 3502 SSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLR 3561
S +Q S G SP+ + G +PK K ++ +G K + +
Sbjct: 533 SKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPK-KAEKAAAEEPRGGLKIESETPVD 591
Query: 3562 TSSSEAHIPDQETTSLTSGTGTPGAE----------AEQQDTASVEQSSQKE-------- 3603
+SS +P + T G+ P + AE++ S +SSQK
Sbjct: 592 LASS---MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDT 648
Query: 3604 -CGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ 3654
++ P Q + P + + +P +VEEE+S F + +++++
Sbjct: 649 SSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKE 700
>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sapiens]
Length = 514
Score = 77.8 bits (190), Expect = 2e-13
Identities = 104/425 (24%), Positives = 173/425 (40%), Gaps = 53/425 (12%)
Query: 3191 PPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP--SNIAPSDV 3248
PP + +++ Q T S+T P + + P + + S+TP S I P++
Sbjct: 3 PPSSSVAATDTGQTTFTSSTATFPET-ITLTPNTNMSRESLMTPMTSTTPITSAITPTNT 61
Query: 3249 VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGG 3308
V++MT + P+ ++ +L L S SS VP+ + + +PLL
Sbjct: 62 VTSMTTMTSPPTTTNSNSTLSSLTSSILSS-TLVPSTDMITSHTTNLTRSSPLL-----A 115
Query: 3309 TAATAAGTSTISQDTSHLTS------GSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHV 3362
T T ST + +T++ TS GS + + S+S+ +SM+T+ PTSS S+P
Sbjct: 116 TLPTTITRSTPTSETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLPPTSS-SLPTTE 174
Query: 3363 TLTNPRL-LGTPDIGSISNLLIKASQQSLGIQDQPVAL---PPSSGMFPQLGTSQTPSTA 3418
T T P L T +I S S +S + + PP+SG
Sbjct: 175 TATTPTTNLVTTEITSHSTPSFSSSTIHSTVSTPTTVISSGPPTSG-------------- 220
Query: 3419 AITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGP 3478
T +SI V PS+ +T I +P+ H+ + LL + DL S
Sbjct: 221 --TIVTSITVTPSSLSTDIPLTTPT--TITHHSVGSTESLLTA--------TDLTSTFTV 268
Query: 3479 QVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKP 3538
S+ T D P+S ++ + S S T P P+ S+ S + P
Sbjct: 269 SSSSAMSTSDIPSSPSIQNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLL----TTFP 324
Query: 3539 KTKRFQLPLD-KGNGKKH--KVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTAS 3595
T F + +G H ++ L S+S H + TT+ T+ T + + ++S
Sbjct: 325 GTYSFSSSMSASSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSS 384
Query: 3596 VEQSS 3600
V +S
Sbjct: 385 VATTS 389
Score = 64.3 bits (155), Expect = 2e-09
Identities = 113/479 (23%), Positives = 188/479 (39%), Gaps = 69/479 (14%)
Query: 3025 NSSTPGLQVPVSPTVPIQNQKYVPNSTDS------PGPSQISNAAVQTTPPH-----LKP 3073
N S L P++ T PI + N+ S P + SN+ + + L P
Sbjct: 36 NMSRESLMTPMTSTTPITSAITPTNTVTSMTTMTSPPTTTNSNSTLSSLTSSILSSTLVP 95
Query: 3074 ATEKLIVVNQNM---QPLYVLQTLPNGVTQKI---QLTSSVSSTPSVMETNTSVLGPMGG 3127
+T+ + N+ PL L TLP +T+ + T S T +V + TS+
Sbjct: 96 STDMITSHTTNLTRSSPL--LATLPTTITRSTPTSETTYPTSPTSTVKGSTTSIR--YST 151
Query: 3128 GLTLTTGLNPSLPTSQSLFPSASKGLLPMSH----HQHLHSFPAATQSSFPPNISNPPSG 3183
+T T + SLP + S P+ P ++ HS P+ + S+ +S P +
Sbjct: 152 SMTGTLSMETSLPPTSSSLPTTETATTPTTNLVTTEITSHSTPSFSSSTIHSTVSTPTTV 211
Query: 3184 LLIGVQPPPDPQLL----VSESSQRTDLS----TTVATPSSGLKKRPISRLQTRKNKKLA 3235
+ G PP ++ V+ SS TD+ TT+ S G + ++ ++
Sbjct: 212 ISSG--PPTSGTIVTSITVTPSSLSTDIPLTTPTTITHHSVGSTESLLTATDLTSTFTVS 269
Query: 3236 PSS--TPSNIAPSDVVSNM---TLINFTPSQLPN-HPSLLDLGSLNTSSHRTV------- 3282
SS + S+I S + N +L++ T + +P+ P+ + TSS T
Sbjct: 270 SSSAMSTSDIPSSPSIQNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLLTTFPGTYSF 329
Query: 3283 PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASS----- 3337
+ + S + E LP S TA T+ + TS TS ++ +SS
Sbjct: 330 SSSMSASSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSSVATTS 389
Query: 3338 ------SSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLG 3391
SS + TT TPT+ S TLT P SI+ S ++
Sbjct: 390 TGQTTFSSSTATFTETTTLTPTTDFS---EETLTTAMTSTPPITSSITPTNTVTSMTTM- 445
Query: 3392 IQDQPVALPPSSGMFPQ-LGTSQTPSTAAITAASS----ICVLPSTQTTGITAASPSGE 3445
P A S + L ++ PST T+ ++ + L +T T IT ++P+ E
Sbjct: 446 -TSWPTATNTLSSLTTNILSSTPVPSTERTTSHTTNINPVSTLVTTLPTTITRSTPTAE 503
Score = 54.7 bits (130), Expect = 2e-06
Identities = 73/332 (21%), Positives = 130/332 (39%), Gaps = 48/332 (14%)
Query: 2081 PDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVIS 2140
P +T T+ S TS S+S + E PP+ P ++T+ + ++++
Sbjct: 126 PTSETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLPPTSSSLPTTETATTPTTNLVT 185
Query: 2141 -KVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSS 2199
++ TPS+S + T H V+ ++SSG + G+ +S
Sbjct: 186 TEITSHSTPSFSSS-----------------TIHSTVSTPTTVISSGPPTSGT---IVTS 225
Query: 2200 LSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVL---GPLNSSTSL 2256
++ S L P+ T T + ++V S + TATDL S+ V + SS S+
Sbjct: 226 ITVTPSSLSTDIPLTTPTTITHHSVGSTESLLTATDLTSTFTVSSSSAMSTSDIPSSPSI 285
Query: 2257 GQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQ--SSASDLVSKSSSLKGEKTKVLSSK 2314
QNT TSS + T T+ + + ++ ++ S SSS+ S
Sbjct: 286 -QNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLLTTFPGTYSFSSSM---------SA 335
Query: 2315 SSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHL-- 2372
SS+G+ H +P +H T + A ++ SF++ + P +
Sbjct: 336 SSDGTTHTETITSLPASTSTLHTTAE--------STTAHTTTTSFTTSTTMESPSSSVAT 387
Query: 2373 --RGQRNDRDQHTDSTQSANSSPDEDTEVKTL 2402
GQ T++ +P D +TL
Sbjct: 388 TSTGQTTFSSSTATFTETTTLTPTTDFSEETL 419
Score = 32.7 bits (73), Expect = 7.4
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 23/144 (15%)
Query: 703 TPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRL 762
TPS + S I +V+ P+ S+G +SG + + I P S S +
Sbjct: 193 TPSFSSSTIHSTVSTPTTVISSGPPTSGT--------IVTSITVTPSSLSTDI------- 237
Query: 763 SSSELSPLTPPSSVSS-SLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTS 821
PLT P++++ S+ + S L + L TFT S S + + +TS
Sbjct: 238 ------PLTTPTTITHHSVGSTESLLTATDLTSTFTVSSSSAMSTSDIPSSPSIQNTETS 291
Query: 822 APAEPFSSSSPTPLFPWFTPGSQT 845
+ S++ P+ + P FT T
Sbjct: 292 SLVSMTSATIPS-VRPTFTSTHNT 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 178,238,860
Number of Sequences: 37866
Number of extensions: 10214457
Number of successful extensions: 123979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 788
Number of HSP's successfully gapped in prelim test: 2404
Number of HSP's that attempted gapping in prelim test: 55078
Number of HSP's gapped (non-prelim): 51871
length of query: 3969
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3847
effective length of database: 13,627,866
effective search space: 52426400502
effective search space used: 52426400502
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.