BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens] (345 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens] 690 0.0 gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens] 685 0.0 gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens] 368 e-102 gi|12669915 E2F transcription factor 4 [Homo sapiens] 351 5e-97 gi|4758226 E2F transcription factor 2 [Homo sapiens] 162 3e-40 gi|4503433 E2F transcription factor 3 [Homo sapiens] 158 8e-39 gi|12669911 E2F transcription factor 1 [Homo sapiens] 146 2e-35 gi|109637795 E2F transcription factor 6 [Homo sapiens] 125 4e-29 gi|145580626 E2F transcription factor 7 [Homo sapiens] 54 2e-07 gi|38505226 E2F family member 8 [Homo sapiens] 52 6e-07 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 42 8e-04 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 41 0.002 gi|87299628 biorientation of chromosomes in cell division 1-like... 41 0.002 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 41 0.002 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 40 0.002 gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 40 0.003 gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 40 0.003 gi|189491742 ataxin 7 isoform b [Homo sapiens] 40 0.004 gi|4506797 ataxin 7 isoform a [Homo sapiens] 40 0.004 gi|238859557 regulatory factor X1 [Homo sapiens] 39 0.005 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 39 0.007 gi|110431370 espin [Homo sapiens] 39 0.007 gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo ... 39 0.007 gi|5454112 transcription factor Dp-2 (E2F dimerization partner 2... 39 0.007 gi|156104908 myosin heavy chain 6 [Homo sapiens] 39 0.009 gi|7706687 Enah/Vasp-like [Homo sapiens] 39 0.009 gi|39812378 RAN binding protein 9 [Homo sapiens] 38 0.012 gi|169167201 PREDICTED: hypothetical protein [Homo sapiens] 38 0.012 gi|169166894 PREDICTED: hypothetical protein [Homo sapiens] 38 0.012 gi|169166324 PREDICTED: hypothetical protein [Homo sapiens] 38 0.012 >gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens] Length = 345 Score = 690 bits (1780), Expect = 0.0 Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT 60 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT Sbjct: 1 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT 60 Query: 61 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG 120 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG Sbjct: 61 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG 120 Query: 121 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN 180 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN Sbjct: 121 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN 180 Query: 181 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV 240 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV Sbjct: 181 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV 240 Query: 241 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSISGD 300 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSISGD Sbjct: 241 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSISGD 300 Query: 301 IIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY 345 IIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY Sbjct: 301 IIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY 345 >gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens] Length = 346 Score = 685 bits (1768), Expect = 0.0 Identities = 345/346 (99%), Positives = 345/346 (99%), Gaps = 1/346 (0%) Query: 1 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT 60 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT Sbjct: 1 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT 60 Query: 61 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG 120 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG Sbjct: 61 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG 120 Query: 121 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN 180 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN Sbjct: 121 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN 180 Query: 181 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV 240 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV Sbjct: 181 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV 240 Query: 241 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISS-GSISG 299 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISS GSISG Sbjct: 241 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG 300 Query: 300 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY 345 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY Sbjct: 301 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY 346 >gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens] Length = 185 Score = 368 bits (944), Expect = e-102 Identities = 184/185 (99%), Positives = 184/185 (99%), Gaps = 1/185 (0%) Query: 162 MDDSINNRFSYVTHEDICNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHS 221 MDDSINNRFSYVTHEDICNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHS Sbjct: 1 MDDSINNRFSYVTHEDICNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHS 60 Query: 222 GPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERS 281 GPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERS Sbjct: 61 GPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERS 120 Query: 282 QALQQTSATDISS-GSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDV 340 QALQQTSATDISS GSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDV Sbjct: 121 QALQQTSATDISSAGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDV 180 Query: 341 QILNY 345 QILNY Sbjct: 181 QILNY 185 >gi|12669915 E2F transcription factor 4 [Homo sapiens] Length = 413 Score = 351 bits (901), Expect = 5e-97 Identities = 213/414 (51%), Positives = 250/414 (60%), Gaps = 109/414 (26%) Query: 33 PQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIY 92 PQ PPPP G SRHEKSLGLLTTKFVSLLQEAKDGVLDLK AADTLAVRQKRRIY Sbjct: 6 PQAPPPP------GTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIY 59 Query: 93 DITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKL 152 DITNVLEGI LIEKKSKNSIQWKGVG GCNT+E+ D+L LKAEIE+L+ +E+ELDQ K+ Sbjct: 60 DITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKV 119 Query: 153 WLQQSIKNVMDDSINNRFSYVTHEDICNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKK 212 W+QQSI+NV +D N+ +YVTHEDIC CF GDTLLAI+APSGT LEVPIPE G NGQKK Sbjct: 120 WVQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAIRAPSGTSLEVPIPE-GLNGQKK 178 Query: 213 YQINLKSHSGPIHVLLINKESSSSKPVVFPV---------------PPP---------DD 248 YQI+LKS SGPI VLL+NKE+ SS PV PV PPP + Sbjct: 179 YQIHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQE 238 Query: 249 LTQPSSQSLTPV-------------------------TPQKSSMATQNLPEQHVSERSQA 283 ++P+S LTP T K S +LP + ++ Sbjct: 239 ASRPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRP 298 Query: 284 LQQTSATDISSGS----------------------------------------------- 296 LQ ++ D SS S Sbjct: 299 LQSSALLDSSSSSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDP 358 Query: 297 ----ISGDIIDELMSSDVF-PLLRLSPTPAD-DYNFNLDDNEGVCDLFDVQILN 344 +S ++++ELMSS+VF PLLRLSP P D DY +NLD++EGVCDLFDV +LN Sbjct: 359 TRECMSSELLEELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFDVPVLN 412 >gi|4758226 E2F transcription factor 2 [Homo sapiens] Length = 437 Score = 162 bits (411), Expect = 3e-40 Identities = 121/320 (37%), Positives = 169/320 (52%), Gaps = 25/320 (7%) Query: 37 PPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITN 96 P P+ + G +R++ SLGLLT KF+ LL E++DGVLDL AA+ L V QKRRIYDITN Sbjct: 116 PSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDV-QKRRIYDITN 174 Query: 97 VLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQ 156 VLEGI LI KK+KN+IQW G G + + + L E+++L E+ LDQ Sbjct: 175 VLEGIQLIRKKAKNNIQWVGRGMFEDPTRP-GKQQQLGQELKELMNTEQALDQLIQSCSL 233 Query: 157 SIKNVMDDSINNRFSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQ 214 S K++ +D N R +YVT++DI F T++A++AP T+LEVP + Q Sbjct: 234 SFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVP-----DRTEDNLQ 288 Query: 215 INLKSHSGPIHVLLINKE-SSSSKPVVFPVP------PPDDLTQPSSQSLTPVTPQKSSM 267 I LKS GPI V L +E P P+P P D QPSS + + +S Sbjct: 289 IYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASS 348 Query: 268 ATQNLPEQHVSERSQALQQTSATDISSGSISGDII----DELMSSDV---FPLLRLSPT- 319 P + +L ATD S + ++ D+ +S + PL+ SP+ Sbjct: 349 VPAPAPTPQQAPPPPSLVPLEATD-SLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSL 407 Query: 320 PADDYNFNLDDNEGVCDLFD 339 DDY + L+ EG+ DLFD Sbjct: 408 DQDDYLWGLEAGEGISDLFD 427 >gi|4503433 E2F transcription factor 3 [Homo sapiens] Length = 465 Score = 158 bits (399), Expect = 8e-39 Identities = 115/338 (34%), Positives = 179/338 (52%), Gaps = 41/338 (12%) Query: 8 SSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQ 67 S G + P G+G+ P P+ P P + +R++ SLGLLT KF+ LL Sbjct: 147 SDGLKTPKGKGRAALRSPDSPKT----PKSPSE-------KTRYDTSLGLLTKKFIQLLS 195 Query: 68 EAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKE-- 125 ++ DGVLDL AA+ L V QKRRIYDITNVLEGI LI+KKSKN++QW GC+ E Sbjct: 196 QSPDGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKKKSKNNVQW----MGCSLSEDG 250 Query: 126 -VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDI--CNCF 182 ++ + + L E+ +L +E++LD+ +K + +DS N R +YVT++DI + Sbjct: 251 GMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGL 310 Query: 183 NGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFP 242 T++ ++AP T+LEVP + + QI+L S GPI V L +E+ + P+ Sbjct: 311 KDQTVIVVKAPPETRLEVP------DSIESLQIHLASTQGPIEVYLCPEETETHSPMKTN 364 Query: 243 VPPPD-DLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSISGDI 301 + ++ +P+S+ L S + ++ + LQQT D ++ G Sbjct: 365 NQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTE--DQIPSNLEGPF 422 Query: 302 IDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFD 339 ++ L PLL+ +DY +L + EG+ DLFD Sbjct: 423 VNLLP-----PLLQ------EDYLLSLGEEEGISDLFD 449 >gi|12669911 E2F transcription factor 1 [Homo sapiens] Length = 437 Score = 146 bits (369), Expect = 2e-35 Identities = 132/407 (32%), Positives = 185/407 (45%), Gaps = 91/407 (22%) Query: 2 AAAEPASSGQQAPAG-----------QGQGQRPPPQPPQAQAPQPPPPPQLG-------- 42 A+A PA +G APA Q RP P P+ +PP +L Sbjct: 42 ASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYL 101 Query: 43 --------------GAG----GGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLA 84 G G G SR+E SL L T +F+ LL + DGV+DL AA+ L Sbjct: 102 AESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLK 161 Query: 85 VRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKE 144 V QKRRIYDITNVLEGI LI KKSKN IQW G T V RL L ++ L+ E Sbjct: 162 V-QKRRIYDITNVLEGIQLIAKKSKNHIQWLG---SHTTVGVGGRLEGLTQDLRQLQESE 217 Query: 145 RELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFN--GDTLLAIQAPSGTQLEVPI 202 ++LD ++ + +D+ + R +YVT +D+ + + ++ I+AP TQL+ Sbjct: 218 QQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQ--- 274 Query: 203 PEMGQNGQKKYQINLKSHSGPIHVLLINKE----------------------SSSSKPVV 240 + + +QI+LKS GPI V L +E ++ S +V Sbjct: 275 ---AVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIV 331 Query: 241 FPVP--PPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSIS 298 P P PP LT SQSL +L ++ + R +L+ D S ++ Sbjct: 332 SPPPSSPPSSLTTDPSQSLL------------SLEQEPLLSRMGSLRAPVDEDRLSPLVA 379 Query: 299 GDIIDELMSSDVFPLL-----RLSPT-PADDYNFNLDDNEGVCDLFD 339 D + E + D LL LSP A DY+F L++ EG+ DLFD Sbjct: 380 ADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFD 426 >gi|109637795 E2F transcription factor 6 [Homo sapiens] Length = 281 Score = 125 bits (315), Expect = 4e-29 Identities = 82/226 (36%), Positives = 124/226 (54%), Gaps = 22/226 (9%) Query: 50 RHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSK 109 R + SL LT KF+ L++ A G+LDL A L VR KRR+YDITNVL+GIDL+EKKSK Sbjct: 63 RFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVR-KRRVYDITNVLDGIDLVEKKSK 121 Query: 110 NSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNR 169 N I+W +G+ + + + + L+ E+ DL E LD+ Q + + DD N R Sbjct: 122 NHIRW--IGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENER 179 Query: 170 FSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVL 227 +YVT++DI F+ ++A++AP+ T+L+VP P + ++++S +GPI V Sbjct: 180 LAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPR-----EDSITVHIRSTNGPIDVY 234 Query: 228 LI--------NKES----SSSKPVVFPVPPPDDLTQPSSQSLTPVT 261 L NK S +SS P P ++ S+ L V+ Sbjct: 235 LCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVS 280 >gi|145580626 E2F transcription factor 7 [Homo sapiens] Length = 911 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 16/125 (12%) Query: 49 SRHEKSLGLLTTKFV----SLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLI 104 SR +KSLGLL KF+ S + + L A +L V ++RRIYDI NVLE + L+ Sbjct: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGV-ERRRIYDIVNVLESLHLV 199 Query: 105 EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 + +KN W G + T + RL +E++ ++Q +LQQ +++D Sbjct: 200 SRVAKNQYGWHGRHSLPKTLRNLQRLG-----------EEQKYEEQMAYLQQKELDLIDY 248 Query: 165 SINNR 169 R Sbjct: 249 KFGER 253 Score = 41.2 bits (95), Expect = 0.001 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 29/134 (21%) Query: 20 GQRPPPQPPQAQAPQ-----PPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVL 74 G+R P +Q Q P P + +SR +KSL +++ KFV L +K ++ Sbjct: 251 GERKKDGDPDSQEQQLLDFSEPDCP----SSSANSRKDKSLRIMSQKFVMLFLVSKTKIV 306 Query: 75 DLKAAADTLAVRQK------------RRIYDITNVLEGIDLI-------EKKSKNSIQWK 115 L AA L + RR+YDI NVL + LI E+ K + +W Sbjct: 307 TLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWI 366 Query: 116 G-VGAGCNTKEVID 128 G V + +E++D Sbjct: 367 GPVDFSSSDEELVD 380 >gi|38505226 E2F family member 8 [Homo sapiens] Length = 867 Score = 52.4 bits (124), Expect = 6e-07 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 12/138 (8%) Query: 49 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVR---QKRRIYDITNVLEGIDLIE 105 SR EKSLGLL KF++ + ++ D +A ++RRIYDI NVLE + ++ Sbjct: 112 SRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVS 171 Query: 106 KKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLE----LKERELDQQKLWLQQSIKNV 161 + +KN W G N + + L+ + E + E +K++E +Q+ +++ ++ Sbjct: 172 RLAKNRYTWHG---RHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKS--YSI 226 Query: 162 MDDSINNRFSYVTHEDIC 179 D I + H D+C Sbjct: 227 EDHIIKSNTGPNGHPDMC 244 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 20/115 (17%) Query: 44 AGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQK-------------RR 90 A +SR +KSL +++ KFV L + ++ L+ AA L RR Sbjct: 255 AASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRR 314 Query: 91 IYDITNVLEGIDLI-------EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIE 138 +YDI NVL +DLI E+ K + +W G NT + + +++E Sbjct: 315 LYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLE 369 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 42.0 bits (97), Expect = 8e-04 Identities = 29/109 (26%), Positives = 61/109 (55%), Gaps = 2/109 (1%) Query: 58 LTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGV 117 L K V+LL+E D L +++ AD+LA ++R I N ++ I++ ++ + + + + Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEI 935 Query: 118 GAGCNTKE--VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 A K+ + D LK +I+DLEL +++++K + +KN+ ++ Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 984 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Query: 58 LTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGV 117 L K VSLLQE D L ++A D LA ++R I N ++ +++ ++ + + Sbjct: 873 LEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 932 Query: 118 GAGCNTK--EVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 A K ++ D LK +I+DLEL +++++K + +KN+ ++ Sbjct: 933 NAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEE 981 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/35 (57%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 14 PAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGS 48 P Q PPP PPQ Q PQPPPPP GAG G+ Sbjct: 5 PQPQPPPPAPPPPPPQPQ-PQPPPPPPGPGAGPGA 38 Score = 35.4 bits (80), Expect = 0.075 Identities = 14/26 (53%), Positives = 15/26 (57%) Query: 23 PPPQPPQAQAPQPPPPPQLGGAGGGS 48 PPP PQ Q P PPP P G GG+ Sbjct: 16 PPPPQPQPQPPPPPPGPGAGPGAGGA 41 Score = 31.6 bits (70), Expect = 1.1 Identities = 18/33 (54%), Positives = 19/33 (57%), Gaps = 9/33 (27%) Query: 23 PPPQP-PQAQAPQPPPP-----PQLGGAGGGSS 49 PPPQP PQ P PPPP P GGAGG + Sbjct: 17 PPPQPQPQ---PPPPPPGPGAGPGAGGAGGAGA 46 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/109 (26%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Query: 58 LTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGV 117 L K V+L+QE D L ++A AD+LA ++R I ++ I++ ++ + + + Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936 Query: 118 GAGCNTK--EVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 A K ++ D LK +I+DLEL +++++K + +KN+ ++ Sbjct: 937 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/109 (26%), Positives = 58/109 (53%), Gaps = 2/109 (1%) Query: 58 LTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGV 117 L K V+L+QE D L ++A AD LA ++R I ++ I++ ++ + + + Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936 Query: 118 GAGCNTKE--VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 A K+ + D LK +I+DLEL +++++K + +KN+ ++ Sbjct: 937 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985 >gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [Homo sapiens] Length = 650 Score = 40.0 bits (92), Expect = 0.003 Identities = 18/32 (56%), Positives = 20/32 (62%), Gaps = 2/32 (6%) Query: 9 SGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQ 40 +G Q P Q Q PPP PP +Q P PPPPPQ Sbjct: 374 AGSQQPPPQPQP--PPPPPPASQQPPPPPPPQ 403 Score = 29.6 bits (65), Expect = 4.1 Identities = 17/40 (42%), Positives = 18/40 (45%), Gaps = 3/40 (7%) Query: 5 EPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGA 44 +P PA Q Q PPP PPQA PP P L A Sbjct: 382 QPQPPPPPPPASQ---QPPPPPPPQAPVRLPPGGPLLPSA 418 >gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [Homo sapiens] Length = 634 Score = 40.0 bits (92), Expect = 0.003 Identities = 18/32 (56%), Positives = 20/32 (62%), Gaps = 2/32 (6%) Query: 9 SGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQ 40 +G Q P Q Q PPP PP +Q P PPPPPQ Sbjct: 358 AGSQQPPPQPQP--PPPPPPASQQPPPPPPPQ 387 Score = 29.6 bits (65), Expect = 4.1 Identities = 17/40 (42%), Positives = 18/40 (45%), Gaps = 3/40 (7%) Query: 5 EPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGA 44 +P PA Q Q PPP PPQA PP P L A Sbjct: 366 QPQPPPPPPPASQ---QPPPPPPPQAPVRLPPGGPLLPSA 402 >gi|189491742 ataxin 7 isoform b [Homo sapiens] Length = 945 Score = 39.7 bits (91), Expect = 0.004 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 3/51 (5%) Query: 2 AAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPP---PPQLGGAGGGSS 49 A A++ +Q Q Q Q PPPQP + Q P PPP P+ GG G S+ Sbjct: 20 AGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAAST 70 >gi|4506797 ataxin 7 isoform a [Homo sapiens] Length = 892 Score = 39.7 bits (91), Expect = 0.004 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 3/51 (5%) Query: 2 AAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPP---PPQLGGAGGGSS 49 A A++ +Q Q Q Q PPPQP + Q P PPP P+ GG G S+ Sbjct: 20 AGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAAST 70 >gi|238859557 regulatory factor X1 [Homo sapiens] Length = 979 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Query: 1 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPP 39 + AA P S QAP Q Q PP PP APQPP PP Sbjct: 9 LQAAPPPSQPPQAPP---QAQPQPPPPPPPAAPQPPQPP 44 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 6 PASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRH 51 P S PA G PPP PPQ Q P PPPP G G +H Sbjct: 10 PGESPGATPA-PGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQH 54 Score = 32.3 bits (72), Expect = 0.64 Identities = 17/38 (44%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 4 AEPASSGQQAPAGQGQGQRPPPQPPQAQAPQP-PPPPQ 40 A PA P Q+PPP PP A P P P PPQ Sbjct: 16 ATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQ 53 Score = 30.4 bits (67), Expect = 2.4 Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%) Query: 21 QRPPPQP-PQAQAPQPPPPPQLGGA 44 +RPPP P P A +P PPPP GA Sbjct: 759 RRPPPGPAPAAASPGPPPPASPPGA 783 Score = 29.6 bits (65), Expect = 4.1 Identities = 12/23 (52%), Positives = 13/23 (56%) Query: 17 QGQGQRPPPQPPQAQAPQPPPPP 39 +G G RP P AP PPPPP Sbjct: 4 RGGGGRPGESPGATPAPGPPPPP 26 Score = 29.6 bits (65), Expect = 4.1 Identities = 18/56 (32%), Positives = 19/56 (33%), Gaps = 8/56 (14%) Query: 3 AAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPP--------PPQLGGAGGGSSR 50 A P AP Q PPP PP P PP PP+ GG R Sbjct: 19 APGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGR 74 Score = 28.9 bits (63), Expect = 7.0 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 7/57 (12%) Query: 6 PASSGQQAPAGQ------GQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLG 56 PA QQ P G G PP PP+A+A PP GG G + S G Sbjct: 28 PAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEA-LPPEAADEGGPRGRLRSRDSSCG 83 >gi|110431370 espin [Homo sapiens] Length = 854 Score = 38.9 bits (89), Expect = 0.007 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 9/102 (8%) Query: 3 AAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKF 62 AA+P +S + P PPP P A +P P PP L AG G + S +TK Sbjct: 586 AADPKASRELPPPPPPP---PPPLPEAASSPPPAPPLPLESAGPGCGQRRSSSSTGSTKS 642 Query: 63 VSLLQEAKDG---VLDLKAAADTLAVRQKRRIYDITNVLEGI 101 +++ D + ++KA Q + +T V GI Sbjct: 643 FNMMSPTGDNSELLAEIKAGKSLKPTPQSK---GLTTVFSGI 681 Score = 29.6 bits (65), Expect = 4.1 Identities = 10/18 (55%), Positives = 11/18 (61%) Query: 22 RPPPQPPQAQAPQPPPPP 39 +P P PP P PPPPP Sbjct: 427 KPTPPPPPPSFPPPPPPP 444 Score = 29.3 bits (64), Expect = 5.4 Identities = 13/28 (46%), Positives = 13/28 (46%) Query: 14 PAGQGQGQRPPPQPPQAQAPQPPPPPQL 41 P G PPP PP P PPP QL Sbjct: 421 PRGTIGKPTPPPPPPSFPPPPPPPGTQL 448 Score = 29.3 bits (64), Expect = 5.4 Identities = 12/28 (42%), Positives = 13/28 (46%) Query: 10 GQQAPAGQGQGQRPPPQPPQAQAPQPPP 37 G+ P PPP PP Q P PPP Sbjct: 426 GKPTPPPPPPSFPPPPPPPGTQLPPPPP 453 >gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo sapiens] Length = 963 Score = 38.9 bits (89), Expect = 0.007 Identities = 19/41 (46%), Positives = 22/41 (53%) Query: 9 SGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSS 49 SGQ+ Q+PPPQ Q Q PQ P PP+L A SS Sbjct: 18 SGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSS 58 >gi|5454112 transcription factor Dp-2 (E2F dimerization partner 2) [Homo sapiens] Length = 386 Score = 38.9 bits (89), Expect = 0.007 Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 13/78 (16%) Query: 79 AADTLAVRQK---RRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG----CNTKEV----- 126 AAD+ A QK RR+YD NVL +++I K+ K I+W G+ C E+ Sbjct: 109 AADSQAYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEIEKQRR 167 Query: 127 IDRLRYLKAEIEDLELKE 144 I+R++ +A++++L L++ Sbjct: 168 IERIKQKRAQLQELLLQQ 185 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 38.5 bits (88), Expect = 0.009 Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Query: 58 LTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGV 117 L K VSLLQE D L ++A D L ++R I N ++ +++ ++ + + Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 934 Query: 118 GAGCNTKE--VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164 A K+ + D LK +I+DLEL +++++K + +KN+ ++ Sbjct: 935 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 983 >gi|7706687 Enah/Vasp-like [Homo sapiens] Length = 418 Score = 38.5 bits (88), Expect = 0.009 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 8/54 (14%) Query: 2 AAAEPAS-SGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKS 54 AA+ P S SG P PPP PP PPPPP L G S H++S Sbjct: 174 AASAPVSCSGPPPPP-------PPPVPPPPTGATPPPPPPLPAGGAQGSSHDES 220 Score = 37.4 bits (85), Expect = 0.020 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 8 SSGQQAPAGQGQGQRPPPQP---PQAQAPQPPPPPQLGGAGGGSSRHEKSL 55 SS AP PPP P P A PPPPP G GSS E S+ Sbjct: 172 SSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSM 222 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 38.1 bits (87), Expect = 0.012 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 8/46 (17%) Query: 2 AAAEPASSGQQAPAGQGQGQR--------PPPQPPQAQAPQPPPPP 39 A + PA S G+G G PPP PP AP PPPPP Sbjct: 43 AGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPP 88 Score = 28.5 bits (62), Expect = 9.2 Identities = 14/30 (46%), Positives = 14/30 (46%), Gaps = 3/30 (10%) Query: 20 GQRPPPQPPQAQAP---QPPPPPQLGGAGG 46 GQ PPP P Q Q PPPP L G Sbjct: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSG 32 Score = 28.5 bits (62), Expect = 9.2 Identities = 12/22 (54%), Positives = 12/22 (54%) Query: 18 GQGQRPPPQPPQAQAPQPPPPP 39 GQ PPPQ Q Q PPPP Sbjct: 3 GQPPPPPPQQQQQQQQLSPPPP 24 >gi|169167201 PREDICTED: hypothetical protein [Homo sapiens] Length = 145 Score = 38.1 bits (87), Expect = 0.012 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 2 AAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSR 50 A A+PASS Q P + RPP A P PP P Q GG G SR Sbjct: 58 ARAQPASSAAQLP----RSHRPPAPSAPAHLPAPPLPAQEGGTTGTLSR 102 >gi|169166894 PREDICTED: hypothetical protein [Homo sapiens] Length = 145 Score = 38.1 bits (87), Expect = 0.012 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 2 AAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSR 50 A A+PASS Q P + RPP A P PP P Q GG G SR Sbjct: 58 ARAQPASSAAQLP----RSHRPPAPSAPAHLPAPPLPAQEGGTTGTLSR 102 >gi|169166324 PREDICTED: hypothetical protein [Homo sapiens] Length = 145 Score = 38.1 bits (87), Expect = 0.012 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 2 AAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSR 50 A A+PASS Q P + RPP A P PP P Q GG G SR Sbjct: 58 ARAQPASSAAQLP----RSHRPPAPSAPAHLPAPPLPAQEGGTTGTLSR 102 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,949,817 Number of Sequences: 37866 Number of extensions: 917938 Number of successful extensions: 19576 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 442 Number of HSP's successfully gapped in prelim test: 408 Number of HSP's that attempted gapping in prelim test: 11463 Number of HSP's gapped (non-prelim): 5910 length of query: 345 length of database: 18,247,518 effective HSP length: 103 effective length of query: 242 effective length of database: 14,347,320 effective search space: 3472051440 effective search space used: 3472051440 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.