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Search of human proteins with 55956788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956788 nucleolin [Homo sapiens]
(710 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956788 nucleolin [Homo sapiens] 1412 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 113 5e-25
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 113 5e-25
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 113 5e-25
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 108 1e-23
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 105 1e-22
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 104 3e-22
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 103 7e-22
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 102 9e-22
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom... 102 2e-21
gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Hom... 102 2e-21
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 101 2e-21
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 101 2e-21
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 100 5e-21
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 98 2e-20
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 97 5e-20
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 94 6e-19
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 92 1e-18
gi|4502847 cold inducible RNA binding protein [Homo sapiens] 91 4e-18
gi|21735415 centromere protein B [Homo sapiens] 87 4e-17
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 84 3e-16
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 84 5e-16
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 83 8e-16
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 82 1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 81 4e-15
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 80 5e-15
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 80 5e-15
gi|226497574 RNA binding motif protein 19 [Homo sapiens] 80 5e-15
gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c ... 80 7e-15
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 80 9e-15
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 1412 bits (3655), Expect = 0.0
Identities = 710/710 (100%), Positives = 710/710 (100%)
Query: 1 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS 60
MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS
Sbjct: 1 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS 60
Query: 61 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA 120
AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA
Sbjct: 61 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA 120
Query: 121 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA
Sbjct: 121 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
Query: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE
Sbjct: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
Query: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG 300
DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG 300
Query: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL 360
TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL
Sbjct: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL 360
Query: 361 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR 420
EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR
Sbjct: 361 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR 420
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST
Sbjct: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL 540
WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL
Sbjct: 481 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL 540
Query: 541 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI 600
NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI
Sbjct: 541 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI 600
Query: 601 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR 660
VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR
Sbjct: 601 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR 660
Query: 661 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE 710
GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
Sbjct: 661 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE 710
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 113 bits (283), Expect = 5e-25
Identities = 98/358 (27%), Positives = 169/358 (47%), Gaps = 34/358 (9%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSP--AGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
+ V G I++ + S ++ + KNL + L + F I +
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
+V + SKG A++ F+T+ A+K E+ G ++ R + + + + + G K
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK--- 186
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
+ E + + N +E+L+E+F K +KV ++ NGKSKG+ F+ + EDA
Sbjct: 187 -AKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
Query: 538 EALNSCNKREIEGRAI---RLELQGPRGSPNARS-----------QPSKTLFVKGLSEDT 583
+A+ N +EI G+ I R + + R + R L++K L +
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
Query: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
+E L++ F GS+ + V E G SKGFGFV F+S E+A A M +G I G+K
Sbjct: 306 DDEKLRKEFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKAVTEM-NGRIVGSK 361
Score = 83.6 bits (205), Expect = 6e-16
Identities = 79/274 (28%), Positives = 123/274 (44%), Gaps = 31/274 (11%)
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
+L +L VT+ L E F A + V +D +S G AY+ F+ ADAE+ +
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
I G+ I + ++ ++ + G N + + NL S + L + F
Sbjct: 72 MNFDVIKGKPIRIMWS-QRDPSLRKSGVGN---------VFIKNLDKSIDNKALYDTFSA 121
Query: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
I KV ++NG SKGYAF+ F + E A +A+ N + R + R E +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVD 616
G A+++ +++K E+ +E+LKE F G + V G SKGFGFV
Sbjct: 181 AELG---AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVS 237
Query: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
+ EDA A E M EI G + + A+ K E
Sbjct: 238 YEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 9e-14
Identities = 63/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
++ + +V FE+ E +KA+E L KVF K K + + K ++ + K
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIK 196
Query: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
N +V + LKE+F + V +GKSKG ++ ++ DA K EE G EI
Sbjct: 197 NFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Query: 455 DGRSISLYYTGEKGQNQ--------DYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVF 506
G+ I + +K + Q + + S + G + L + NL + +E L++ F
Sbjct: 257 SGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--LYIKNLDDTIDDEKLRKEF 314
Query: 507 E---KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
T KV ++G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 315 SPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVAL 367
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 566 ARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEED 622
A S P +L+V L D TE L E F + + R+ D T S G+ +V+F D
Sbjct: 5 ASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 64
Query: 623 AKAAKEAMEDGEIDGNKVTLDWAK 646
A+ A + M I G + + W++
Sbjct: 65 AERALDTMNFDVIKGKPIRIMWSQ 88
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 113 bits (283), Expect = 5e-25
Identities = 98/358 (27%), Positives = 169/358 (47%), Gaps = 34/358 (9%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSP--AGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
+ V G I++ + S ++ + KNL + L + F I +
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
+V + SKG A++ F+T+ A+K E+ G ++ R + + + + + G K
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK--- 186
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
+ E + + N +E+L+E+F K +KV ++ NGKSKG+ F+ + EDA
Sbjct: 187 -AKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
Query: 538 EALNSCNKREIEGRAI---RLELQGPRGSPNARS-----------QPSKTLFVKGLSEDT 583
+A+ N +EI G+ I R + + R + R L++K L +
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
Query: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
+E L++ F GS+ + V E G SKGFGFV F+S E+A A M +G I G+K
Sbjct: 306 DDEKLRKEFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKAVTEM-NGRIVGSK 361
Score = 83.6 bits (205), Expect = 6e-16
Identities = 79/274 (28%), Positives = 123/274 (44%), Gaps = 31/274 (11%)
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
+L +L VT+ L E F A + V +D +S G AY+ F+ ADAE+ +
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
I G+ I + ++ ++ + G N + + NL S + L + F
Sbjct: 72 MNFDVIKGKPIRIMWS-QRDPSLRKSGVGN---------VFIKNLDKSIDNKALYDTFSA 121
Query: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
I KV ++NG SKGYAF+ F + E A +A+ N + R + R E +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVD 616
G A+++ +++K E+ +E+LKE F G + V G SKGFGFV
Sbjct: 181 AELG---AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVS 237
Query: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
+ EDA A E M EI G + + A+ K E
Sbjct: 238 YEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 9e-14
Identities = 63/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
++ + +V FE+ E +KA+E L KVF K K + + K ++ + K
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIK 196
Query: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
N +V + LKE+F + V +GKSKG ++ ++ DA K EE G EI
Sbjct: 197 NFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Query: 455 DGRSISLYYTGEKGQNQ--------DYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVF 506
G+ I + +K + Q + + S + G + L + NL + +E L++ F
Sbjct: 257 SGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--LYIKNLDDTIDDEKLRKEF 314
Query: 507 E---KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
T KV ++G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 315 SPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVAL 367
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 566 ARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEED 622
A S P +L+V L D TE L E F + + R+ D T S G+ +V+F D
Sbjct: 5 ASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 64
Query: 623 AKAAKEAMEDGEIDGNKVTLDWAK 646
A+ A + M I G + + W++
Sbjct: 65 AERALDTMNFDVIKGKPIRIMWSQ 88
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 113 bits (283), Expect = 5e-25
Identities = 98/358 (27%), Positives = 169/358 (47%), Gaps = 34/358 (9%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSP--AGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
+ V G I++ + S ++ + KNL + L + F I +
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
+V + SKG A++ F+T+ A+K E+ G ++ R + + + + + G K
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK--- 186
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
+ E + + N +E+L+E+F K +KV ++ NGKSKG+ F+ + EDA
Sbjct: 187 -AKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
Query: 538 EALNSCNKREIEGRAI---RLELQGPRGSPNARS-----------QPSKTLFVKGLSEDT 583
+A+ N +EI G+ I R + + R + R L++K L +
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
Query: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
+E L++ F GS+ + V E G SKGFGFV F+S E+A A M +G I G+K
Sbjct: 306 DDEKLRKEFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKAVTEM-NGRIVGSK 361
Score = 83.6 bits (205), Expect = 6e-16
Identities = 79/274 (28%), Positives = 123/274 (44%), Gaps = 31/274 (11%)
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
+L +L VT+ L E F A + V +D +S G AY+ F+ ADAE+ +
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
I G+ I + ++ ++ + G N + + NL S + L + F
Sbjct: 72 MNFDVIKGKPIRIMWS-QRDPSLRKSGVGN---------VFIKNLDKSIDNKALYDTFSA 121
Query: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
I KV ++NG SKGYAF+ F + E A +A+ N + R + R E +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVD 616
G A+++ +++K E+ +E+LKE F G + V G SKGFGFV
Sbjct: 181 AELG---AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVS 237
Query: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
+ EDA A E M EI G + + A+ K E
Sbjct: 238 YEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 9e-14
Identities = 63/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
++ + +V FE+ E +KA+E L KVF K K + + K ++ + K
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIK 196
Query: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
N +V + LKE+F + V +GKSKG ++ ++ DA K EE G EI
Sbjct: 197 NFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Query: 455 DGRSISLYYTGEKGQNQ--------DYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVF 506
G+ I + +K + Q + + S + G + L + NL + +E L++ F
Sbjct: 257 SGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--LYIKNLDDTIDDEKLRKEF 314
Query: 507 E---KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
T KV ++G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 315 SPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVAL 367
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 566 ARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEED 622
A S P +L+V L D TE L E F + + R+ D T S G+ +V+F D
Sbjct: 5 ASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 64
Query: 623 AKAAKEAMEDGEIDGNKVTLDWAK 646
A+ A + M I G + + W++
Sbjct: 65 AERALDTMNFDVIKGKPIRIMWSQ 88
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 108 bits (271), Expect = 1e-23
Identities = 99/358 (27%), Positives = 168/358 (46%), Gaps = 34/358 (9%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
+L+VG+L+ + + L S V L++ R +TR+ + YV+F D +KAL
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPV--LSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
Query: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
+ + G I+L + + + KNL + L E F +I +
Sbjct: 69 DTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
++S D SKG A++ F+ ++ A++ EE G + G + + G + +N+ R + +
Sbjct: 129 VMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV---FVG-RFKNRKDREAELRS 184
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
+ E + + N +E L++VF K +KV + +GKSKG+ F+ F S E AK
Sbjct: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
Query: 538 EALNSCNKREIEGRAI-------RLELQGPRGS-------PNARSQPSKTLFVKGLSEDT 583
+A+ N R+I G+ I ++E Q R L++K L +
Sbjct: 245 KAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTI 304
Query: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
+E L+ F GS+ +R+ +E G SKGFG + F+S EDA A M +G I G+K
Sbjct: 305 DDEKLRNEFSSFGSI-SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEM-NGRILGSK 360
Score = 83.6 bits (205), Expect = 6e-16
Identities = 74/236 (31%), Positives = 113/236 (47%), Gaps = 26/236 (11%)
Query: 427 KSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDY--RGGKNSTWSGE 484
+S G AY+ F ADA+K + I G+SI L ++ Q Y R G + +
Sbjct: 49 RSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWS----QRDAYLRRSGIGNVF--- 101
Query: 485 SKTLVLSNLSYSATEETLQE---VFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALN 541
+ NL S +TL E F K KV + G SKGYAF+ F + A A+
Sbjct: 102 -----IKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIE 155
Query: 542 SCNKREIEGRAIRLELQGPRGSPNA--RSQPSK--TLFVKGLSEDTTEETLKESFDG--- 594
N + ++G + + R A RS+ S+ +++K D +E LK+ F
Sbjct: 156 EMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGK 215
Query: 595 SVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
++ +++TD +G SKGFGFV F+S E AK A E M +I+G + + A+ K E
Sbjct: 216 TLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270
Score = 68.6 bits (166), Expect = 2e-11
Identities = 60/232 (25%), Positives = 106/232 (45%), Gaps = 21/232 (9%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKDSK-KERDARTLLAK 398
++ + +V F++ ++A+E L G KVF K K + + + K + + K
Sbjct: 136 SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIK 195
Query: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
N + + LK+VF + V GKSKG ++ F + A+K EE G +I
Sbjct: 196 NFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDI 255
Query: 455 DGRSISLYYTGEKGQNQD-----YRGGKNSTWSG-ESKTLVLSNLSYSATEETLQEVFEK 508
+G+ I + +K + Q + K G + L + NL + +E L+ F
Sbjct: 256 NGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSS 315
Query: 509 ---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
+ +KV Q + G+SKG+ I F+S EDA +A+ N R + + + + L
Sbjct: 316 FGSISRVKVMQEE-GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
Score = 48.1 bits (113), Expect = 3e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALE-L 366
N+++ N + LK S + V+ G ++ FG+V F+S E +KA+E +
Sbjct: 191 NVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEM 250
Query: 367 TGLKVFGNEIKLEKPKGK------------DSKKER----DARTLLAKNLPYKVTQDELK 410
G + G I + + + K K+ER L KNL + ++L+
Sbjct: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
Query: 411 EVFED---AAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISL 461
F + ++++ ++G+SKG I F + DA K E G + + +S+
Sbjct: 311 NEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
Score = 38.1 bits (87), Expect = 0.028
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 573 TLFVKGLSEDTTEETLKESFD--GSVRA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEA 629
+L+V L D TE+ L F G V + RI D+ T S G+ +V+F DA+ A +
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 630 MEDGEIDGNKVTLDWAK 646
M I G + L W++
Sbjct: 71 MNFDIIKGKSIRLMWSQ 87
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 105 bits (262), Expect = 1e-22
Identities = 85/247 (34%), Positives = 125/247 (50%), Gaps = 37/247 (14%)
Query: 486 KTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ T+E+L+ FE+ T V ++ N K S+G+ F+ +A+ E+ A+N
Sbjct: 14 RKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMN 73
Query: 542 SCNKREIEGRAIRLELQGPRGS---PNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ +++GR + + R P A K +FV G+ EDT E L++ F+ G +
Sbjct: 74 A-RPHKVDGRVVEPKRAVSREDSQRPGAHLTVKK-IFVGGIKEDTEEHHLRDYFEQYGKI 131
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPK------- 648
I+TDR +G +GF FV F+ + D+ + ++G+ + A K
Sbjct: 132 EVIEIMTDRGSGKKRGFAFVTFD-DHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS 190
Query: 649 ----GEGGFGGRGGGRGG-FGG-----RGGGRGGRGGFGG-RGRGGFGGRG------GFR 691
G G G GGGRGG FGG RGG GRGGFGG RG GG+GG G G
Sbjct: 191 SSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND 250
Query: 692 GGRGGGG 698
GG GGGG
Sbjct: 251 GGYGGGG 257
Score = 60.8 bits (146), Expect = 4e-09
Identities = 76/340 (22%), Positives = 128/340 (37%), Gaps = 43/340 (12%)
Query: 382 KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR--LVSKDG---KSKGIAYIEF 436
K + K+ R L L ++ T + L+ FE + +V +D +S+G ++ +
Sbjct: 3 KSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTY 62
Query: 437 KTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYS 496
T + + + ++DGR + + +Q R G + T K + + +
Sbjct: 63 ATVEEVDAAMNARPH-KVDGRVVEPKRAVSREDSQ--RPGAHLT----VKKIFVGGIKED 115
Query: 497 ATEETLQEVFEKATFIKVPQ----NQNGKSKGYAFIEFASFEDAKEAL----NSCNKREI 548
E L++ FE+ I+V + +GK +G+AF+ F + + + ++ N
Sbjct: 116 TEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNC 175
Query: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTT-EETLKESFDGSVRARIVTDRETG 607
E R + + S + R + F G + + S R R G
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGG 235
Query: 608 S--SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGG 665
G G+ F + DG G P GG G G G G+G
Sbjct: 236 GYGGSGDGYNGFGN------------DGGYGGGG-------PGYSGGSRGYGSGGQGYGN 276
Query: 666 RGGGRGGRGGFGGRGRGGFGGRGGFRGGR-GGGGDHKPQG 704
+G G GG G + GG GG GG G GGGG + G
Sbjct: 277 QGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFG 316
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 104 bits (259), Expect = 3e-22
Identities = 93/358 (25%), Positives = 168/358 (46%), Gaps = 34/358 (9%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSP--AGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
+ V G +++ + S ++ + KNL + L + F I +
Sbjct: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
+V + SKG ++ F+T+ AE+ E+ G ++ R + + + + + G +
Sbjct: 130 VVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAR--- 186
Query: 481 WSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
+ E + + N +E L+++F K A +KV +++GKSKG+ F+ F EDA+
Sbjct: 187 -AKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245
Query: 538 EALNSCNKREIEGRAI---RLELQGPRGSPNARS-----------QPSKTLFVKGLSEDT 583
+A++ N +E+ G+ I R + + R + R L+VK L +
Sbjct: 246 KAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGI 305
Query: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
+E L++ F G++ + V E G SKGFGFV F+S E+A A M +G I K
Sbjct: 306 DDERLRKEFSPFGTITSAKVM-MEGGRSKGFGFVCFSSPEEATKAVTEM-NGRIVATK 361
Score = 89.0 bits (219), Expect = 1e-17
Identities = 79/275 (28%), Positives = 130/275 (47%), Gaps = 33/275 (12%)
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
+L +L VT+ L E F A I V +D +S G AY+ F+ ADAE+ +
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
I G+ + + ++ ++ + G N + + NL S + L + F
Sbjct: 72 MNFDVIKGKPVRIMWS-QRDPSLRKSGVGN---------IFIKNLDKSIDNKALYDTFSA 121
Query: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
I KV ++NG SKGY F+ F + E A+ A+ N + R + R E +
Sbjct: 122 FGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKE---SFDGSVRARIVTDRETGSSKGFGFV 615
G AR++ +++K ED +E LK+ F ++ +++TD E+G SKGFGFV
Sbjct: 181 AELG---ARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFV 236
Query: 616 DFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
F EDA+ A + M E++G ++ + A+ K E
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVE 271
Score = 74.3 bits (181), Expect = 4e-13
Identities = 60/232 (25%), Positives = 111/232 (47%), Gaps = 21/232 (9%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
++ +G+V FE+ E E+A+E L KVF K K + + + ++ + K
Sbjct: 137 SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIK 196
Query: 399 NLPYKVTQDELKEVFED---AAEIRLVSKD-GKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
N + + LK++F A +++++ + GKSKG ++ F+ DA+K +E G E+
Sbjct: 197 NFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL 256
Query: 455 DGRSISLYYTGEKGQNQDYRGGKNSTWSGESKT------LVLSNLSYSATEETLQEVFEK 508
+G+ I + +K + Q K + T L + NL +E L++ F
Sbjct: 257 NGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSP 316
Query: 509 ---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
T KV + G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 317 FGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
Score = 51.2 bits (121), Expect = 3e-06
Identities = 53/232 (22%), Positives = 99/232 (42%), Gaps = 26/232 (11%)
Query: 264 EEEEEEEEPVKEAPGK----RKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKS 319
E +E E +++ G RK + + K+ E + + G N+++ N +
Sbjct: 146 ETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEL--GARAKEFTNVYIKNFGEDMD 203
Query: 320 APELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEI-- 376
LK + V+ G ++ FG+V FE ED +KA+ E+ G ++ G +I
Sbjct: 204 DERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
Query: 377 -----KLE-----KPKGKDSKKERDAR----TLLAKNLPYKVTQDELKEVFEDAAEI--- 419
K+E K K + K++R R L KNL + + L++ F I
Sbjct: 264 GRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSA 323
Query: 420 RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQ 471
+++ + G+SKG ++ F + +A K E G + + + + K + Q
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQ 375
Score = 47.0 bits (110), Expect = 6e-05
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 563 SPNARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNS 619
+P+A S P +L+V L D TE L E F + + R+ D T S G+ +V+F
Sbjct: 2 NPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQ 61
Query: 620 EEDAKAAKEAMEDGEIDGNKVTLDWAK 646
DA+ A + M I G V + W++
Sbjct: 62 PADAERALDTMNFDVIKGKPVRIMWSQ 88
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 103 bits (256), Expect = 7e-22
Identities = 81/314 (25%), Positives = 148/314 (47%), Gaps = 29/314 (9%)
Query: 349 FGYVDFESAEDLEKALELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQD 407
+ YV+F+ +D E AL+ V G +++ + S ++ + KNL +
Sbjct: 54 YAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNK 113
Query: 408 ELKEV---FEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYT 464
L + F + +V + SKG ++ F+T AE+ ++ G ++GR + +
Sbjct: 114 ALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQF 173
Query: 465 GEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK 521
+ + + G + + E + + N +E L+++F K A +KV +++GK
Sbjct: 174 KSRKEREAELGAR----AKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGK 229
Query: 522 SKGYAFIEFASFEDAKEALNSCNKREIEGRAI---RLELQGPRGSPNARSQPSK------ 572
SKG+ F+ F EDA++A++ N +E+ G+ I R + + R + R+
Sbjct: 230 SKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRIT 289
Query: 573 -----TLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKA 625
L+VK L + +E L+++F G++ + V E G SKGFGFV F+S E+A
Sbjct: 290 RYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVM-MEGGRSKGFGFVCFSSPEEATK 348
Query: 626 AKEAMEDGEIDGNK 639
A M +G I K
Sbjct: 349 AVTEM-NGRIVATK 361
Score = 83.2 bits (204), Expect = 8e-16
Identities = 75/275 (27%), Positives = 125/275 (45%), Gaps = 33/275 (12%)
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRLVS--KD---GKSKGIAYIEFKTEADAEKTFEE 448
+L +L VT+ L E F A I + +D S AY+ F+ DAE +
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEV--- 505
I G+ + + ++ ++ + G N + + NL S + L +
Sbjct: 72 MNFDVIKGKPVRIMWS-QRDPSLRKSGVGN---------IFVKNLDKSINNKALYDTVSA 121
Query: 506 FEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
F V ++NG SKGY F+ F + E A+ A+ N + GR + R E +
Sbjct: 122 FGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180
Query: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKE---SFDGSVRARIVTDRETGSSKGFGFV 615
G AR++ +++K ED +E LK+ F ++ +++TD E+G SKGFGFV
Sbjct: 181 AELG---ARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFV 236
Query: 616 DFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
F EDA+ A + M E++G ++ + A+ K E
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 9e-14
Identities = 70/276 (25%), Positives = 132/276 (47%), Gaps = 34/276 (12%)
Query: 308 NLFVGNLNF---NKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKAL 364
N+FV NL+ NK+ + + ++ + N VV G ++ +G+V FE+ E E+A+
Sbjct: 100 NIFVKNLDKSINNKALYDTVSAFGNILSCN---VVCDENG-SKGYGFVHFETHEAAERAI 155
Query: 365 E------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAKNLPYKVTQDELKEVFED-- 415
+ L G KVF + K K + + + ++ + KN + + LK++F
Sbjct: 156 KKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFG 215
Query: 416 -AAEIRLVSKD-GKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDY 473
A +++++ + GKSKG ++ F+ DA+K +E G E++G+ I Y G + +
Sbjct: 216 PALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQI---YVGRAQKKVER 272
Query: 474 RGGKNSTWSGESK---------TLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK 521
+ T+ + L + NL +E L++ F T KV + G+
Sbjct: 273 QTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMM-EGGR 331
Query: 522 SKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/234 (21%), Positives = 96/234 (41%), Gaps = 26/234 (11%)
Query: 264 EEEEEEEEPVKEAPGK----RKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKS 319
E E E +K+ G RK + + K+ E + + G N+++ N +
Sbjct: 146 ETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAEL--GARAKEFPNVYIKNFGEDMD 203
Query: 320 APELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKL 378
LK + V+ G ++ FG+V FE ED +KA+ E+ G ++ G +I +
Sbjct: 204 DERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
Query: 379 EKPKGKDSKKERDART----------------LLAKNLPYKVTQDELKEVFEDAAEI--- 419
+ + K ++ RT L KNL + + L++ F I
Sbjct: 264 GRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSA 323
Query: 420 RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDY 473
+++ + G+SKG ++ F + +A K E G + + + + K + Q Y
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAY 377
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 563 SPNARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNS 619
+P+ S P+ +L+V L D TE L E F + + RI D T S + +V+F
Sbjct: 2 NPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQH 61
Query: 620 EEDAKAAKEAMEDGEIDGNKVTLDWAK 646
+DA+ A + M I G V + W++
Sbjct: 62 TKDAEHALDTMNFDVIKGKPVRIMWSQ 88
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 102 bits (255), Expect = 9e-22
Identities = 85/254 (33%), Positives = 127/254 (50%), Gaps = 38/254 (14%)
Query: 486 KTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ T+E+L+ FE+ T V ++ N K S+G+ F+ +A+ E+ A+N
Sbjct: 14 RKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMN 73
Query: 542 SCNKREIEGRAIRLELQGPRGS---PNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ +++GR + + R P A K +FV G+ EDT E L++ F+ G +
Sbjct: 74 A-RPHKVDGRVVEPKRAVSREDSQRPGAHLTVKK-IFVGGIKEDTEEHHLRDYFEQYGKI 131
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPK------- 648
I+TDR +G +GF FV F+ + D+ + ++G+ + A K
Sbjct: 132 EVIEIMTDRGSGKKRGFAFVTFD-DHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS 190
Query: 649 ----GEGGFGGRGGGR-GGFG-----GRGGGRGGRGGFGG-RGRGGFGGRG-GFRG---- 692
G G G GGGR GGFG GRGG GRGGFGG RG GG+GG G G+ G
Sbjct: 191 SSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND 250
Query: 693 --GRGGGGDHKPQG 704
GGGG + G
Sbjct: 251 GSNFGGGGSYNDFG 264
>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
sapiens]
Length = 320
Score = 102 bits (253), Expect = 2e-21
Identities = 85/254 (33%), Positives = 126/254 (49%), Gaps = 38/254 (14%)
Query: 486 KTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ T+E+L+ FE+ T V ++ N K S+G+ F+ +A+ E+ A+N
Sbjct: 14 RKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMN 73
Query: 542 SCNKREIEGRAIRLELQGPRGS---PNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ +++GR + + R P A K +FV G+ EDT E L++ F+ G +
Sbjct: 74 T-TPHKVDGRVVEPKRAVSREDSQRPGAHLTVKK-IFVGGIKEDTEEHHLRDYFEQYGKI 131
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPK------- 648
I+TDR +G +GF FV F+ + D+ + + G+ + A PK
Sbjct: 132 EVIEIMTDRGSGKKRGFAFVTFD-DHDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASAS 190
Query: 649 ----GEGGFGGRGGGRG-GFG-----GRGGGRGGRGGFGGR-GRGGFGGRG-GFRG---- 692
G G G GGGRG GFG GRGG GRGGFGG G GG+GG G G+ G
Sbjct: 191 SSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFGND 250
Query: 693 --GRGGGGDHKPQG 704
GGGG + G
Sbjct: 251 GSNFGGGGSYNDFG 264
>gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Homo
sapiens]
Length = 320
Score = 102 bits (253), Expect = 2e-21
Identities = 85/254 (33%), Positives = 126/254 (49%), Gaps = 38/254 (14%)
Query: 486 KTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ T+E+L+ FE+ T V ++ N K S+G+ F+ +A+ E+ A+N
Sbjct: 14 RKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMN 73
Query: 542 SCNKREIEGRAIRLELQGPRGS---PNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ +++GR + + R P A K +FV G+ EDT E L++ F+ G +
Sbjct: 74 T-TPHKVDGRVVEPKRAVSREDSQRPGAHLTVKK-IFVGGIKEDTEEHHLRDYFEQYGKI 131
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPK------- 648
I+TDR +G +GF FV F+ + D+ + + G+ + A PK
Sbjct: 132 EVIEIMTDRGSGKKRGFAFVTFD-DHDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASAS 190
Query: 649 ----GEGGFGGRGGGRG-GFG-----GRGGGRGGRGGFGGR-GRGGFGGRG-GFRG---- 692
G G G GGGRG GFG GRGG GRGGFGG G GG+GG G G+ G
Sbjct: 191 SSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFGND 250
Query: 693 --GRGGGGDHKPQG 704
GGGG + G
Sbjct: 251 GSNFGGGGSYNDFG 264
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 101 bits (252), Expect = 2e-21
Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 41/256 (16%)
Query: 486 KTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ TEE+L+ +E K T V ++ K S+G+ F+ F+S + A+
Sbjct: 21 RKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAM- 79
Query: 542 SCNKREIEGRAI---RLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ I+GR + R + G P A K LFV G+ EDT E L++ F+ G +
Sbjct: 80 AARPHSIDGRVVEPKRAVAREESGKPGAHVTVKK-LFVGGIKEDTEEHHLRDYFEEYGKI 138
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEE------------------DAKAAKEAMEDGEIDG 637
I+TDR++G +GFGFV F+ + + + A E E+
Sbjct: 139 DTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQS 198
Query: 638 NKV----TLDWAKPKGEGGFGGRGGG---RGGFGGRGGGRGGRGGF----GGRGRGGFGG 686
++ + +G GG G G G RGG G G GRG G+ GG G G FGG
Sbjct: 199 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGG 258
Query: 687 RGGFRGGRGGGGDHKP 702
G+ GGRGG G P
Sbjct: 259 SPGYGGGRGGYGGGGP 274
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/336 (22%), Positives = 126/336 (37%), Gaps = 48/336 (14%)
Query: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR--LVSKDGKSK---GIAYIE 435
P + +++ R L L ++ T++ L+ +E ++ +V +D SK G ++
Sbjct: 9 PLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVT 68
Query: 436 FKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
F + A+ + + + IDGR + + + + G + T K L + +
Sbjct: 69 FSSMAEVDAAMAARPHS-IDGRVVEPKRA--VAREESGKPGAHVT----VKKLFVGGIKE 121
Query: 496 SATEETLQEVFEKA----TFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGR 551
E L++ FE+ T + Q+GK +G+ F+ F + +
Sbjct: 122 DTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDK------------- 168
Query: 552 AIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKG 611
I L+ NA + K LS +E R G + G
Sbjct: 169 -IVLQKYHTINGHNAEVR-------KALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFG 220
Query: 612 FG-FVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGR---GGGRGGFGGRG 667
G +F D + DG +G + G G FGG GGGRGG+GG G
Sbjct: 221 PGPGSNFRGGSDGYGSGRGFGDG-YNG------YGGGPGGGNFGGSPGYGGGRGGYGGGG 273
Query: 668 GGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQ 703
G G +GG G G +GG G G++ Q
Sbjct: 274 PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQ 309
Score = 36.2 bits (82), Expect = 0.11
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 647 PKGEGGFGGRGGGRGGFGGRG---GGRGGRGGFGGRGR 681
P G FGG G +GG GG GG GG+GGR R
Sbjct: 315 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSR 352
Score = 33.9 bits (76), Expect = 0.54
Identities = 18/37 (48%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 654 GGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGF 690
G GG R G GGG G GG G G GG+GGR +
Sbjct: 319 GNFGGSRNMGGPYGGGNYGPGGSG--GSGGYGGRSRY 353
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 101 bits (252), Expect = 2e-21
Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 41/256 (16%)
Query: 486 KTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGK-SKGYAFIEFASFEDAKEALN 541
+ L + LS+ TEE+L+ +E K T V ++ K S+G+ F+ F+S + A+
Sbjct: 9 RKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAM- 67
Query: 542 SCNKREIEGRAI---RLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV 596
+ I+GR + R + G P A K LFV G+ EDT E L++ F+ G +
Sbjct: 68 AARPHSIDGRVVEPKRAVAREESGKPGAHVTVKK-LFVGGIKEDTEEHHLRDYFEEYGKI 126
Query: 597 RA-RIVTDRETGSSKGFGFVDFNSEE------------------DAKAAKEAMEDGEIDG 637
I+TDR++G +GFGFV F+ + + + A E E+
Sbjct: 127 DTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQS 186
Query: 638 NKV----TLDWAKPKGEGGFGGRGGG---RGGFGGRGGGRGGRGGF----GGRGRGGFGG 686
++ + +G GG G G G RGG G G GRG G+ GG G G FGG
Sbjct: 187 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGG 246
Query: 687 RGGFRGGRGGGGDHKP 702
G+ GGRGG G P
Sbjct: 247 SPGYGGGRGGYGGGGP 262
Score = 57.0 bits (136), Expect = 6e-08
Identities = 74/330 (22%), Positives = 124/330 (37%), Gaps = 48/330 (14%)
Query: 387 KKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR--LVSKDGKSK---GIAYIEFKTEAD 441
+++ R L L ++ T++ L+ +E ++ +V +D SK G ++ F + A+
Sbjct: 3 REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAE 62
Query: 442 AEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEET 501
+ + + IDGR + + + + G + T K L + + E
Sbjct: 63 VDAAMAARPHS-IDGRVVEPKRA--VAREESGKPGAHVT----VKKLFVGGIKEDTEEHH 115
Query: 502 LQEVFEKA----TFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
L++ FE+ T + Q+GK +G+ F+ F + + I L+
Sbjct: 116 LRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDK--------------IVLQK 161
Query: 558 QGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGFG-FVD 616
NA + K LS +E R G + G G +
Sbjct: 162 YHTINGHNAEVR-------KALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSN 214
Query: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGR---GGGRGGFGGRGGGRGGR 673
F D + DG +G + G G FGG GGGRGG+GG G G G +
Sbjct: 215 FRGGSDGYGSGRGFGDG-YNG------YGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQ 267
Query: 674 GGFGGRGRGGFGGRGGFRGGRGGGGDHKPQ 703
GG G G +GG G G++ Q
Sbjct: 268 GGGYGGGYDNYGGGNYGSGNYNDFGNYNQQ 297
Score = 36.2 bits (82), Expect = 0.11
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 647 PKGEGGFGGRGGGRGGFGGRG---GGRGGRGGFGGRGR 681
P G FGG G +GG GG GG GG+GGR R
Sbjct: 303 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSR 340
Score = 33.9 bits (76), Expect = 0.54
Identities = 18/37 (48%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 654 GGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGF 690
G GG R G GGG G GG G G GG+GGR +
Sbjct: 307 GNFGGSRNMGGPYGGGNYGPGGSG--GSGGYGGRSRY 341
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 100 bits (249), Expect = 5e-21
Identities = 84/284 (29%), Positives = 129/284 (45%), Gaps = 54/284 (19%)
Query: 466 EKGQNQDYRG--GKNSTWSGESKTLVLSNLSYSATEETLQEVFEK----ATFIKVPQNQN 519
+ G+ + RG G + + + L + LS+ T+++L+E FEK + + Q
Sbjct: 13 DSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQT 72
Query: 520 GKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGS---PNARSQPSKTLFV 576
+S+G+ F+ ++ E+ A+ +++GR + + R P A K +FV
Sbjct: 73 KRSRGFGFVTYSCVEEVDAAM-CARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKK-IFV 130
Query: 577 KGLSEDTTEETLKESFD--GSVRA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDG 633
G+ EDT E L++ F+ G + ++ DR++G +GF FV F+ + D +
Sbjct: 131 GGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFD-DHDTVDKIVVQKYH 189
Query: 634 EIDGNKVTLDWAKPK--------------GEGGFGGRGGGRGGFGG---RGGGRGGRGGF 676
I+G+ + A K G G F GRGG GG GG RGG GGRGG+
Sbjct: 190 TINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGY 249
Query: 677 GGRGRG-------------GFGGRGG---------FRGGRGGGG 698
GG G G GFGG GG RGG GGGG
Sbjct: 250 GGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGG 293
Score = 65.5 bits (158), Expect = 2e-10
Identities = 78/338 (23%), Positives = 128/338 (37%), Gaps = 43/338 (12%)
Query: 382 KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR--LVSKDG---KSKGIAYIEF 436
+G D K+ R L L ++ T D L+E FE + +V +D +S+G ++ +
Sbjct: 24 EGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTY 83
Query: 437 KTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYS 496
+ + + ++DGR + + + G + T K + + +
Sbjct: 84 SCVEEVDAAMCARPH-KVDGRVVEPKRAVSR--EDSVKPGAHLT----VKKIFVGGIKED 136
Query: 497 ATEETLQEVFEK----ATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL----NSCNKREI 548
E L++ FEK T + Q+GK +G+AF+ F + + + ++ N
Sbjct: 137 TEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNC 196
Query: 549 E-GRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETG 607
E +A+ + GS R S +G +F G G
Sbjct: 197 EVKKALSKQEMQSAGSQRGRGGGSGNFMGRG-----------GNFGGG-GGNFGRGGNFG 244
Query: 608 SSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRG 667
G+G S DG ++ G GG GGG G+G +G
Sbjct: 245 GRGGYGGGGGGSRGSYGGGDGGYNGFGGDGG----NYGGGPGYSSRGGYGGGGPGYGNQG 300
Query: 668 GGRGGRGGFGGRGRGG-FGGRGGFRGGRGGGGDHKPQG 704
GG GG GG+ G GG FGG G GGGG++ G
Sbjct: 301 GGYGGGGGYDGYNEGGNFGG-----GNYGGGGNYNDFG 333
Score = 35.4 bits (80), Expect = 0.18
Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 22/74 (29%)
Query: 649 GEGGFGGRGGGRGGFGGRGGGRGGR--------------------GGFGGRGRGG-FGGR 687
G GG+ G G G FGG G GG G FGGR G +GG
Sbjct: 305 GGGGYDGYNEG-GNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGG 363
Query: 688 GGFRGGRGGGGDHK 701
G GG GG G +
Sbjct: 364 YGSGGGSGGYGSRR 377
Score = 33.5 bits (75), Expect = 0.70
Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 647 PKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGR 679
P G FGGR G GG G G GG GG+G R
Sbjct: 345 PMKGGSFGGRSSGSPYGGGYGSG-GGSGGYGSR 376
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 98.2 bits (243), Expect = 2e-20
Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 15/158 (9%)
Query: 558 QGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD-----------GSVRARIVTDRET 606
QG R + + T+FV+GL E+ T E++ + F G + TDRET
Sbjct: 271 QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
Query: 607 GSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGR 666
G KG V F+ AKAA + + E GN + + +A + + GG G GRGG G
Sbjct: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGG-GNGRGGRG-- 387
Query: 667 GGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQG 704
GG GRGG+GG G GG GGRGGF G GGGG + G
Sbjct: 388 RGGPMGRGGYGGGGSGG-GGRGGFPSGGGGGGGQQRAG 424
Score = 56.2 bits (134), Expect = 1e-07
Identities = 30/54 (55%), Positives = 31/54 (57%), Gaps = 10/54 (18%)
Query: 648 KGEGGFGGRGGGRGGF----------GGRGGGRGGRGGFGGRGRGGFGGRGGFR 691
+G GG GG GGG GG GRGGGRGGRGG GG RGGF GG R
Sbjct: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPR 269
Score = 55.8 bits (133), Expect = 1e-07
Identities = 34/64 (53%), Positives = 38/64 (59%), Gaps = 16/64 (25%)
Query: 651 GGFGGR----GGGRGGFG--GRGG-GRGGRGGFGGRGRGGFG---------GRGGFRGGR 694
GG+G + GGG GG+G RGG GRGG GG GG G GG+ GRGG RGGR
Sbjct: 192 GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251
Query: 695 GGGG 698
GG G
Sbjct: 252 GGMG 255
Score = 50.1 bits (118), Expect = 7e-06
Identities = 30/64 (46%), Positives = 32/64 (50%), Gaps = 14/64 (21%)
Query: 649 GEGGFGGRGGGRG-------GFGGRGGGRGGRGGFGGRGRGGFG-------GRGGFRGGR 694
G GG GG GG G GG GGG G + GG G GG+G GRGG GG
Sbjct: 166 GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGG 225
Query: 695 GGGG 698
GGGG
Sbjct: 226 GGGG 229
Score = 49.7 bits (117), Expect = 9e-06
Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 637 GNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGG 696
G D + GG GG G + GG G G G+ GGRGRGG GG GG GG GG
Sbjct: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGG 231
Query: 697 ----GGDHKPQGK 705
G ++P+G+
Sbjct: 232 YNRSSGGYEPRGR 244
Score = 48.5 bits (114), Expect = 2e-05
Identities = 67/256 (26%), Positives = 97/256 (37%), Gaps = 38/256 (14%)
Query: 482 SGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQN------------QNGKSKGYAFIE 529
+ ++ T+ + L + T E++ + F++ IK + + GK KG A +
Sbjct: 281 NSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVS 340
Query: 530 FASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLK 589
F AK A++ + +E G I++ R N + +G
Sbjct: 341 FDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGG 400
Query: 590 ESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKG 649
S G R S G G D K E+ PK
Sbjct: 401 GSGGGG--------RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKP 452
Query: 650 EGGFGGRGGG----------RGGFGG--RGG--GRGG-RGGFGGRGRGGFGGRGGFRGGR 694
+G GG GG RGG GG RGG GRGG RGGF G GRGG G RGGF G+
Sbjct: 453 DGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG-GRGG-GDRGGFGPGK 510
Query: 695 -GGGGDHKPQGKKTKF 709
G+H+ ++ +
Sbjct: 511 MDSRGEHRQDRRERPY 526
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 97.1 bits (240), Expect = 5e-20
Identities = 76/235 (32%), Positives = 115/235 (48%), Gaps = 29/235 (12%)
Query: 488 LVLSNLSYSATEETLQEVFEK----ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSC 543
L + L+ +E L+ FE + V Q +S+ + F+ +++ E+A A+ +
Sbjct: 9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAM-AA 67
Query: 544 NKREIEGRAIRLELQGPR---GSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSV-R 597
+ ++G + L+ R P A ++ K LFV GL D E L E F G+V +
Sbjct: 68 SPHAVDGNTVELKRAVSREDSARPGAHAKVKK-LFVGGLKGDVAEGDLIEHFSQFGTVEK 126
Query: 598 ARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRG 657
A I+ D+++G +GFGFV F + + A A ++ I G++V + A PK + GG G
Sbjct: 127 AEIIADKQSGKKRGFGFVYFQNHDAADKAA-VVKFHPIQGHRVEVKKAVPKEDIYSGGGG 185
Query: 658 GG----RGGFGGRG------------GGRGGRGGFGGRGRGGFGGRGGFRGGRGG 696
GG RGG GGRG GG GG +GG G GG GG + GG GG
Sbjct: 186 GGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG 240
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 18/193 (9%)
Query: 309 LFVGNLNFNKSAPELKTGISDVFAKND-LAVVDVRIGMTRKFGYVDFESAEDLEKALELT 367
LF+G LN S L+ D + VV+ + +R FG+V + + E+ + A+ +
Sbjct: 9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAAS 68
Query: 368 GLKVFGNEIKLEKPKGKDSKKERDA----RTLLAKNLPYKVTQDELKEVFE-----DAAE 418
V GN ++L++ ++ A + L L V + +L E F + AE
Sbjct: 69 PHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE 128
Query: 419 IRLVSKDGKSKGIAYIEFKTEADAEKT----FEEKQGTEIDGRSI----SLYYTGEKGQN 470
I + GK +G ++ F+ A+K F QG ++ + +Y G G +
Sbjct: 129 IIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGS 188
Query: 471 QDYRGGKNSTWSG 483
+ RGG+ G
Sbjct: 189 RSSRGGRGGRGRG 201
Score = 37.7 bits (86), Expect = 0.037
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 14/72 (19%)
Query: 607 GSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGR 666
GS G GF F S +++ M+ G G GG G GGR G
Sbjct: 245 GSDYGNGFGGFGSYSQHQSSYGPMKSGG--------------GGGGGGSSWGGRSNSGPY 290
Query: 667 GGGRGGRGGFGG 678
GG GG GG+GG
Sbjct: 291 RGGYGGGGGYGG 302
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 93.6 bits (231), Expect = 6e-19
Identities = 86/326 (26%), Positives = 146/326 (44%), Gaps = 35/326 (10%)
Query: 349 FGYVDFESAEDLEKALELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQD 407
+GYV+F D E AL + G +L + D ++ + KNL +
Sbjct: 61 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 120
Query: 408 ELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYT 464
L +F I ++V D SKG AY+ F + A A + G ++ R + Y
Sbjct: 121 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQV---YV 177
Query: 465 GEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGK 521
G ++ + + + N+ +E L+E+F + +KV ++ +GK
Sbjct: 178 GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK 237
Query: 522 SKGYAFIEFASFEDAKEALNSCNKREIEGRA---------------IRLELQGPRGSPNA 566
SKG+ F+ + + E A++A+ + + I+G+ +R + R +
Sbjct: 238 SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKS 297
Query: 567 RSQPSKTLFVKGLSEDTTEETLKESFD--GSV-RARIVTDRETGSSKGFGFVDFNSEEDA 623
R P +++K L E +E LKE F GS+ RA+++ E G KGFG V F+S E+A
Sbjct: 298 R-PPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEA 354
Query: 624 KAAKEAMEDGEIDGNK---VTLDWAK 646
A + M +G I G+K VTL A+
Sbjct: 355 TKAVDEM-NGRIVGSKPLHVTLGQAR 379
Score = 71.2 bits (173), Expect = 3e-12
Identities = 81/288 (28%), Positives = 123/288 (42%), Gaps = 34/288 (11%)
Query: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKDGKSK---GIAYIE 435
P GK K + A L +L VT+D L + F A +R + +D ++ G Y+
Sbjct: 8 PAGKKKKYLKAA--LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
Query: 436 FKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
F+ ADAE I+G+ L ++ D R K+ + + + NL
Sbjct: 66 FRFPADAEWALNTMNFDLINGKPFRLMWS-----QPDDRLRKSGVGN-----IFIKNLDK 115
Query: 496 SATEETLQEVFEKATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRA 552
S L +F I KV + NG SKGYA++ F S A A+ N + R
Sbjct: 116 SIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQ 174
Query: 553 IRLELQGPRGSPNARSQPSKT--------LFVKGLSEDTTEETLKESFD--GSVRARIVT 602
+ + G P R+ +T +FVK + +D +E LKE F G + V
Sbjct: 175 VYV---GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVI 231
Query: 603 DRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
+G SKGFGFV + + E A+ A + IDG + + A+ K E
Sbjct: 232 RDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIE 279
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 20/189 (10%)
Query: 291 PEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFG 350
PE + +V + T N+FV N+ + +LK + + V+ G ++ FG
Sbjct: 183 PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
Query: 351 YVDFESAEDLEKA-LELTGLKVFGNEIKLEKPKGK----------------DSKKERDAR 393
+V +E+ E +KA L+L G + G + + + + K K
Sbjct: 243 FVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGV 302
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQ 450
+ KNL + ++LKE F I +++ + G+ KG + F + +A K +E
Sbjct: 303 PIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMN 362
Query: 451 GTEIDGRSI 459
G + + +
Sbjct: 363 GRIVGSKPL 371
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 562 GSPNARSQPSK----TLFVKGLSEDTTEETLKESFD--GSVR-ARIVTDRETGSSKGFGF 614
G PN + K L+V L D TE+ L + F G +R RI D T S G+G+
Sbjct: 4 GEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGY 63
Query: 615 VDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKP 647
V+F DA+ A M I+G L W++P
Sbjct: 64 VNFRFPADAEWALNTMNFDLINGKPFRLMWSQP 96
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 92.4 bits (228), Expect = 1e-18
Identities = 76/324 (23%), Positives = 144/324 (44%), Gaps = 31/324 (9%)
Query: 340 DVRIGMTRKFGYVDFESAEDLEKALELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAK 398
DV + + Y++F+ D E+AL+ ++ G I++ + ++ + K
Sbjct: 45 DVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIK 104
Query: 399 NLPYKVTQDELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEID 455
NL + L + F I ++ + S+G ++ F+T A++ G ++
Sbjct: 105 NLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLN 164
Query: 456 GRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFE---KATFI 512
R + + + + + + G + + E + + NL E+ LQ++F K +
Sbjct: 165 DRKVFVGHFKSRREREAELGAR----ALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
Query: 513 KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQG------ 559
KV ++ +G S+ + F+ F E+A++A+ N +E+ GR + R+E Q
Sbjct: 221 KVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRF 280
Query: 560 -PRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDG---SVRARIVTDRETGSSKGFGFV 615
R L+VK L + ++ L++ F A+++T E G SKGFGFV
Sbjct: 281 EQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMT--EGGHSKGFGFV 338
Query: 616 DFNSEEDAKAAKEAMEDGEIDGNK 639
F+S E+A A M +G I G K
Sbjct: 339 CFSSPEEATKAVTEM-NGRIVGTK 361
Score = 61.2 bits (147), Expect = 3e-09
Identities = 55/235 (23%), Positives = 101/235 (42%), Gaps = 27/235 (11%)
Query: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
+R FG+V FE+ E ++A+ L KVF K + + + + + + K
Sbjct: 137 SRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVK 196
Query: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
NLP V + L+++F ++ V G S+ ++ F+ +A+K G E+
Sbjct: 197 NLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEV 256
Query: 455 DGRSISLYYTGEKGQNQDYRGGKNSTWSG---------ESKTLVLSNLSYSATEETLQEV 505
GR L Y G + + + + + L + NL S ++ L++
Sbjct: 257 SGR---LLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKE 313
Query: 506 FEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
F T KV + G SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 314 FSPYGVITSAKV-MTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVAL 367
Score = 58.9 bits (141), Expect = 2e-08
Identities = 50/170 (29%), Positives = 82/170 (48%), Gaps = 9/170 (5%)
Query: 487 TLVLSNLSYSATEETLQEVFEKA---TFIKVPQN-QNGKSKGYAFIEFASFEDAKEALNS 542
+L + +L TE L E F A I+V ++ +S GYA+I F DA+ AL++
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 543 CNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARI 600
N ++G+ IR+ + P R +F+K L + + L ++F G++ +
Sbjct: 72 MNFEMLKGQPIRI--MWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
Query: 601 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
V E GS +GFGFV F + E A+ A M ++ KV + K + E
Sbjct: 130 VACDEHGS-RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRE 178
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 20/164 (12%)
Query: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKA-LEL 366
N++V NL + L+ S + V+ G +R FG+V+FE E+ +KA + +
Sbjct: 192 NIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHM 251
Query: 367 TGLKVFG---------------NEIKLEKPKGKDSKKER-DARTLLAKNLPYKVTQDELK 410
G +V G NE+K + K + R L KNL + D+L+
Sbjct: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
Query: 411 EVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQG 451
+ F I +++++ G SKG ++ F + +A K E G
Sbjct: 312 KEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNG 355
Score = 39.3 bits (90), Expect = 0.013
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 570 PSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEEDAKAA 626
P +L+V L D TE L E F + + R+ D T S G+ +++F DA+ A
Sbjct: 9 PLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERA 68
Query: 627 KEAMEDGEIDGNKVTLDWAK 646
+ M + G + + W++
Sbjct: 69 LDTMNFEMLKGQPIRIMWSQ 88
>gi|4502847 cold inducible RNA binding protein [Homo sapiens]
Length = 172
Score = 90.9 bits (224), Expect = 4e-18
Identities = 62/137 (45%), Positives = 77/137 (56%), Gaps = 13/137 (9%)
Query: 574 LFVKGLSEDTTEETLKESFD--GSV-RARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAM 630
LFV GLS DT E++L++ F G + +V DRET S+GFGFV F + +DAK A AM
Sbjct: 8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
Query: 631 EDGEIDGNKVTLDWA----KPKGEGGFGGRGGGRGGF-GGRGGGRGGRGGFGGRGRGG-- 683
+DG ++ +D A + G GG GGRG F GGRG GRG G G RG GG
Sbjct: 68 NGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNR 127
Query: 684 FGGRGGFRGGRGGGGDH 700
F R GG GG D+
Sbjct: 128 FESRS---GGYGGSRDY 141
Score = 53.9 bits (128), Expect = 5e-07
Identities = 49/211 (23%), Positives = 81/211 (38%), Gaps = 64/211 (30%)
Query: 482 SGESKTLVLSNLSYSATEETLQEVFEK----ATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
S E K L + LS+ E++L++VF K + + V + +S+G+ F+ F + +DAK
Sbjct: 3 SDEGK-LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAK 61
Query: 538 EALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVR 597
+A+ + N + ++GR IR++ G +R + +G F G
Sbjct: 62 DAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGF------------FRG--- 106
Query: 598 ARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGG-- 655
G +G GF ++ G+ G+GG
Sbjct: 107 ---------GRGRGRGF------------------------------SRGGGDRGYGGNR 127
Query: 656 ---RGGGRGGFGGRGGGRGGRGGFGGRGRGG 683
R GG GG R GG+ R GG
Sbjct: 128 FESRSGGYGGSRDYYSSRSQSGGYSDRSSGG 158
Score = 40.0 bits (92), Expect = 0.007
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Query: 391 DARTLLAKNLPYKVTQDELKEVFEDAAEIR--LVSKDG---KSKGIAYIEFKTEADAEKT 445
D L L + + L++VF +I +V KD +S+G ++ F+ DA+
Sbjct: 4 DEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
Query: 446 FEEKQGTEIDGRSISLYYTGEKGQNQD--YRGG 476
G +DGR I + G+ N+ YRGG
Sbjct: 64 MMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGG 96
Score = 38.1 bits (87), Expect = 0.028
Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 309 LFVGNLNFNKSAPELKTGISDVFAKNDLAVV-DVRIGMTRKFGYVDFESAEDLEKA-LEL 366
LFVG L+F+ + L+ S +++ VV D +R FG+V FE+ +D + A + +
Sbjct: 8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
Query: 367 TGLKVFGNEIKLEKPKGKDSKKERDAR 393
G V G +I++++ + R R
Sbjct: 68 NGKSVDGRQIRVDQAGKSSDNRSRGYR 94
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 87.4 bits (215), Expect = 4e-17
Identities = 49/162 (30%), Positives = 85/162 (52%), Gaps = 16/162 (9%)
Query: 122 PGKKGAAIPAKGAKNGKNAK-----KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMK 176
P A G G NA K + +EEE+++ EE+EE+ E E+E+E+ E
Sbjct: 377 PSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEG 436
Query: 177 AAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMET-------TPAKGKKAAKVVPVKA 229
E+E +E+ + D D++++E+++S E +E A G A +A
Sbjct: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
Query: 230 K----NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
+ + E ++ + D +E+DD++EDDED+DD+DDEE+ +E
Sbjct: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 14/118 (11%)
Query: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKN 231
P A + E+E++E++E++E++ + EE++ E E E +G++
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELG--------- 443
Query: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289
+EEE +E+ D D DE++E+D++ E E E+ + V EA G A+++A
Sbjct: 444 -----EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 24/129 (18%)
Query: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA-- 181
++G +G + + ++E+ +EE D DS+E+EE+DE+ + E E A A
Sbjct: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGS 486
Query: 182 ----------------------PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK 219
+ D ++EDDE+++D+D+D++DD E+ P+ G+
Sbjct: 487 FGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
Query: 220 KAAKVVPVK 228
A VK
Sbjct: 547 AMAYFAMVK 555
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 10/169 (5%)
Query: 12 GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKK 71
G P + E + E+EE E+EE++ GEE +++G++ + + ++
Sbjct: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEE---EEEEGEEEEEEGGEGEELGEEEE 447
Query: 72 VAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPA 131
V + +++ + A+ V G G ++ A P
Sbjct: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYG-------AQEEAQCPT 500
Query: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
G DS+EE+D++ ++++EDD+D++ED DE+ + A A
Sbjct: 501 LHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMA 549
Score = 47.8 bits (112), Expect = 4e-05
Identities = 21/70 (30%), Positives = 45/70 (64%)
Query: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292
+E E+EEE++E+E++++ E +E++++ ++EEEE E EE +E + + ++ + E
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEE 462
Query: 293 AKKQKVEGTE 302
++ EG E
Sbjct: 463 DEESSSEGLE 472
Score = 42.4 bits (98), Expect = 0.002
Identities = 17/67 (25%), Positives = 44/67 (65%)
Query: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298
+ + E+E+++++E++E++ + ++EEEE EEEEE E ++E +++ ++ +++
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 299 EGTEPTT 305
E E ++
Sbjct: 462 EDEESSS 468
Score = 38.9 bits (89), Expect = 0.017
Identities = 17/61 (27%), Positives = 38/61 (62%)
Query: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
E+E+EE + E+E+++ +E++E+ + ++ EEEE EEE ++ + +++ EA
Sbjct: 414 EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEA 473
Query: 294 K 294
+
Sbjct: 474 E 474
Score = 32.0 bits (71), Expect = 2.0
Identities = 13/46 (28%), Positives = 26/46 (56%)
Query: 22 KEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVS 67
+E +++ ED+E +D++D+ G+EV +P A K+ + S
Sbjct: 515 EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTS 560
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 84.3 bits (207), Expect = 3e-16
Identities = 72/256 (28%), Positives = 116/256 (45%), Gaps = 32/256 (12%)
Query: 469 QNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKA-----TFIKVPQNQNGKSK 523
+ KN +G+ + + LS+ +++ L++ F K IK+ N G+S+
Sbjct: 56 EGDQINASKNEEDAGK---MFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPN-TGRSR 111
Query: 524 GYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDT 583
G+ FI F ++ L+ R ++GR I P+ + + P K +FV GL+ +
Sbjct: 112 GFGFILFKDAASVEKVLDQKEHR-LDGRVI-----DPKKAMAMKKDPVKKIFVGGLNPEA 165
Query: 584 TEETLKESFD--GSVRA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640
TEE ++E F G + A + D + +GF F+ F EE K E + + G+K
Sbjct: 166 TEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK-KFHTVSGSKC 224
Query: 641 TLDWAKPK--------GEGGFGGRGGGR----GGFGGRGGGRGGRGGFGGRGRGGFGGRG 688
+ A+PK G GG G R G GG GG G + G+G G+G +
Sbjct: 225 EIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQ 284
Query: 689 GFRGGRGGGGDHKPQG 704
G+ G GG D+ P G
Sbjct: 285 GYGPGY-GGYDYSPYG 299
Score = 63.2 bits (152), Expect = 8e-10
Identities = 57/241 (23%), Positives = 99/241 (41%), Gaps = 16/241 (6%)
Query: 249 DDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFN 308
+++ E ++ E E E P G A P + EG + + N
Sbjct: 6 EEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKN 65
Query: 309 ------LFVGNLNFNKSAPELKTGISDVFAKNDLAV-VDVRIGMTRKFGYVDFESAEDLE 361
+FVG L+++ S +LK + D + +D G +R FG++ F+ A +E
Sbjct: 66 EEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVE 125
Query: 362 KALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRL 421
K L+ ++ G I PK + K+ + + L + T+++++E F + EI
Sbjct: 126 KVLDQKEHRLDGRVI---DPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEA 182
Query: 422 VS-----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGR-SISLYYTGEKGQNQDYRG 475
+ K K +G +I FK E +K E+K T + I + E Q Q Y
Sbjct: 183 IELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGS 242
Query: 476 G 476
G
Sbjct: 243 G 243
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 84.0 bits (206), Expect = 5e-16
Identities = 80/337 (23%), Positives = 121/337 (35%), Gaps = 58/337 (17%)
Query: 6 KAGKNQGDPKKMAPPPK------------EVEEDSEDEEMSEDEEDDSSGEEVVIPQKKG 53
K G P APPPK E ++ E E S DE D SS EE P K
Sbjct: 285 KPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTK-- 342
Query: 54 KKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGAT 113
VVS K PAKKAA + + + ++ P+K T
Sbjct: 343 ----------AVVS--KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390
Query: 114 PGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPA 173
P +P K AA P + G+ +D ++ E+++ + A
Sbjct: 391 PA-VTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKA 449
Query: 174 AMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAK-VVPVKAKNV 232
KAA + PA + D + D E++ E+ + K +K A P K +
Sbjct: 450 TAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASA 509
Query: 233 AEDEDEEEDDEDEDDDDDEDDE--------------------------DDDDEDDEEEEE 266
+ + E + DD +E++E +EEEEE
Sbjct: 510 KKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEE 569
Query: 267 EEEEEPVKEAPGKRKK----EMAKQKAAPEAKKQKVE 299
+++ V G KK E AK+ P+AKK K++
Sbjct: 570 KKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQ 606
Score = 74.3 bits (181), Expect = 4e-13
Identities = 115/566 (20%), Positives = 211/566 (37%), Gaps = 92/566 (16%)
Query: 54 KKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGAT 113
K A AT A + + + + + + K+A P +K A KA ++ + +
Sbjct: 33 KFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSE 92
Query: 114 PGKALVATPGKKGAAIPAK--GAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIE 171
+ + P KK AA+PAK G GK A K E SEE +DD++ED+ + ++
Sbjct: 93 EEEEVQGPPAKK-AAVPAKRVGLPPGKAAAKAS----ESSSSEESSDDDDEEDQKKQPVQ 147
Query: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK-----KAAKVVP 226
A AA A + D D + +DE +++ + K + K A+ P
Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP 207
Query: 227 VKAKNVAEDEDEEEDDEDEDDDDDEDD----------------------------EDDDD 258
A A DD +E+ +
Sbjct: 208 KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSS 267
Query: 259 EDDEEEEEEEEEEPVKEAPG-----------KRKKEMAKQ--KAAPEAKKQKVEGTEPTT 305
ED +EEEE+++P+K PG KK + Q K A E K+Q VE +E ++
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVE-KQQPVESSEDSS 326
Query: 306 AFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALE 365
+ + + S E K V +K + D +S+ED E +
Sbjct: 327 -------DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSK 379
Query: 366 LTG-LKVFGNEIKLE------KPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAE 418
G K N+ + KP + + LL + +++E E+ +
Sbjct: 380 PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTK 439
Query: 419 IRLVSKDGKSKGIAYI------------EFKTEADAEKTFEEKQGTEIDGRSISLYYTGE 466
+ + K+ A + + +++D+ + EE++ T +
Sbjct: 440 KMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTS---------KSAV 490
Query: 467 KGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYA 526
K + Q GG + +K + + S+++++ +E EK P+ Q K+ G +
Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTS 550
Query: 527 FIEFASFEDAKEALNSCNKREIEGRA 552
+ + ++ K A NS + E + +A
Sbjct: 551 AL---TAQNGKAAKNSEEEEEEKKKA 573
Score = 73.2 bits (178), Expect = 8e-13
Identities = 98/420 (23%), Positives = 142/420 (33%), Gaps = 117/420 (27%)
Query: 3 KLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSG--EEVVIPQKKGKKAAATS 60
K A K G P A SE+ +DEED ++ V PQ K KA
Sbjct: 104 KAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKK 163
Query: 61 AK------------------KVVVSP-TKKVAVATPAKKAAVTP----GK---------- 87
AK K ++P T K P K A P GK
Sbjct: 164 AKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSS 223
Query: 88 ----------KAAATPAKKTV--------TPAKAVTTPGKKGAT-----------PGKAL 118
KAAATP KKTV P KA TTP +K ++ K +
Sbjct: 224 SSSSDDSEEEKAAATP-KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPM 282
Query: 119 VATPGKKGA----AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP-- 172
PG + + P G K+ ++++ +S ED D+ D +E++ P
Sbjct: 283 KNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTK 342
Query: 173 AAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETT------PAKGKKAAKVVP 226
A + A P + E D D D E+D++ + TT PA K+ V P
Sbjct: 343 AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKP 402
Query: 227 VKA---------KNVAEDEDEEEDDEDEDDDDDEDDED---------------------- 255
A K + D +E+ ++E +
Sbjct: 403 AAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA 462
Query: 256 -----DDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAP----EAKKQKVEGTEPTTA 306
D D + EEEEE ++ K+K + AAP AKK K E + +++
Sbjct: 463 PQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS 522
Score = 67.0 bits (162), Expect = 6e-11
Identities = 68/324 (20%), Positives = 109/324 (33%), Gaps = 35/324 (10%)
Query: 11 QGDPKKMA---------PPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSA 61
QG P K A PP K + SE E +DD ++ P +KG K A +A
Sbjct: 98 QGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAA 157
Query: 62 KKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVAT 121
K +P KK AK + + P K VT + A P
Sbjct: 158 K----APPKK------AKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK------ 201
Query: 122 PGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
PA+ A N K S S D+ ++E + P A A
Sbjct: 202 --------PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP 253
Query: 182 PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEED 241
+ ED DEE++ ++ P K++ ++
Sbjct: 254 VKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAV 313
Query: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301
++ + + ED D+ D EEE++ + V +A K AK+ A + + +
Sbjct: 314 EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA--TTKPPPAKKAAESSSDSSDSDSS 371
Query: 302 EPTTAFNLFVGNLNFNKSAPELKT 325
E A + G + + P + T
Sbjct: 372 EDDEAPSKPAGTTKNSSNKPAVTT 395
Score = 33.5 bits (75), Expect = 0.70
Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 9 KNQGDPKKMAPPPKEVE----EDSEDEEMSEDEEDDSSGEEVVIPQKKG--KKAAATSAK 62
K +G P+ AP ++ + + SE+EE++ VV+ + K+ +AK
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAK 593
Query: 63 KVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKK 96
+ KK+ + TP G+K A++P ++
Sbjct: 594 EAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRR 627
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 83.2 bits (204), Expect = 8e-16
Identities = 74/272 (27%), Positives = 114/272 (41%), Gaps = 26/272 (9%)
Query: 448 EKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFE 507
E +G +ID S E N R + +T E + + LS+ T++ L++ F
Sbjct: 62 ESEGAKIDA---SKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118
Query: 508 KATFIKVPQNQ------NGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPR 561
K F +V G+S+G+ F+ F E + ++ + ++ G+ I R
Sbjct: 119 K--FGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ-KEHKLNGKVI----DPKR 171
Query: 562 GSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIV---TDRETGSSKGFGFVDFN 618
+P K +FV GLS DT EE ++E F G + D +T +GF F+ F
Sbjct: 172 AKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFK 231
Query: 619 SEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGG------ 672
EE K E + + +K + A K + + G RGGF GR GRGG
Sbjct: 232 EEEPVKKIME-KKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNW 290
Query: 673 RGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQG 704
G+ G+G G G GG G + G
Sbjct: 291 NQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTG 322
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 82.4 bits (202), Expect = 1e-15
Identities = 61/195 (31%), Positives = 81/195 (41%), Gaps = 56/195 (28%)
Query: 88 KAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDE 147
K P + + + TPG G+ GK G K K +D
Sbjct: 15 KGVRVPVEPAIQELFSCPTPGCDGSGH------VSGKYARHRSVYGCPLAKKRKTQDKQP 68
Query: 148 EED-----------DDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196
+E D S DE DD D ED DE E EDE +E ED++
Sbjct: 69 QEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-------------EDEGEEYSEDND 115
Query: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256
+ D++E+D E D +EEE+ E+ED+DDDED ED
Sbjct: 116 EPGDEDEEDEEG--------------------------DREEEEEIEEEDEDDDEDGEDV 149
Query: 257 DDEDDEEEEEEEEEE 271
+DE++EEEEEEEEEE
Sbjct: 150 EDEEEEEEEEEEEEE 164
Score = 72.4 bits (176), Expect = 1e-12
Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 47/138 (34%)
Query: 143 EDSDEEEDDDSEEDEED-DEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
ED DE+E+D+ EE ED DE DEDE++ E +E++E +E+DEDDD+D
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEE-----------GDREEEEEIEEEDEDDDED 145
Query: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDD----------- 250
ED +EE E+E+EEE++E+E++++D
Sbjct: 146 GEDVEDEE------------------------EEEEEEEEEEEEEENEDHQMNCHNTRIM 181
Query: 251 EDDEDDDDEDDEEEEEEE 268
+D E DD+ +DE + +E
Sbjct: 182 QDTEKDDNNNDEYDNYDE 199
Score = 63.2 bits (152), Expect = 8e-10
Identities = 33/115 (28%), Positives = 61/115 (53%), Gaps = 29/115 (25%)
Query: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDD 198
N + D DEE+++ E+EE+ E+EDED+DE ED +DE++E++E++
Sbjct: 114 NDEPGDEDEEDEEGDREEEEEIEEEDEDDDE-------------DGEDVEDEEEEEEEEE 160
Query: 199 DDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253
+++EE+++E+ M N +D E+DD + D+ D+ D+
Sbjct: 161 EEEEEEENEDHQM----------------NCHNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 53.5 bits (127), Expect = 7e-07
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 28/132 (21%)
Query: 135 KNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194
+ G ++E+ +EE++DD +ED ED EDE+E+E+E E E+E++E++ED
Sbjct: 125 EEGDREEEEEIEEEDEDD-DEDGEDVEDEEEEEEEEE-------------EEEEEEENED 170
Query: 195 --------------DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
++DD++++E D+ +E + + K A+ +A+ +E
Sbjct: 171 HQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTS 230
Query: 241 DDEDEDDDDDED 252
+ ++D D +E+
Sbjct: 231 NSLEDDSDKNEN 242
Score = 53.1 bits (126), Expect = 9e-07
Identities = 33/138 (23%), Positives = 63/138 (45%), Gaps = 31/138 (22%)
Query: 165 EDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKV 224
+D+ EPA + A A DE D+ D +D DE++
Sbjct: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-------------------- 103
Query: 225 VPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEM 284
EDE E+ +++D+ ++DE+D++ D EEEEE EEE+ + G+ ++
Sbjct: 104 -----------EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
Query: 285 AKQKAAPEAKKQKVEGTE 302
+++ E ++++ E +
Sbjct: 153 EEEEEEEEEEEEEEENED 170
Score = 53.1 bits (126), Expect = 9e-07
Identities = 26/114 (22%), Positives = 60/114 (52%), Gaps = 34/114 (29%)
Query: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197
++ + E+ D EE+++ EE++EDD+++ ED EDE++E++E++E+
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGED-----------------VEDEEEEEEEEEEE 162
Query: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251
++++E +D + T + +D ++++++ DE D+ DE
Sbjct: 163 EEEEENEDHQMNCHNT-----------------RIMQDTEKDDNNNDEYDNYDE 199
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/96 (22%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266
+ + + P + K VKA + + DE ++ D ++ D+ +ED+ ++ ED++E +
Sbjct: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119
Query: 267 EEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
E+EE+ +E + ++E+ ++ + + VE E
Sbjct: 120 EDEED--EEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 80.9 bits (198), Expect = 4e-15
Identities = 107/480 (22%), Positives = 180/480 (37%), Gaps = 35/480 (7%)
Query: 5 AKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQK-------KGKKAA 57
AK+ P+K P KE E S E S ++E+ S EV P+K + K A
Sbjct: 538 AKSPAEVKSPEKAKSPAKE-EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 58 ATSAKKVVVSPTKKVA-----VATPAKKAAVTPGK-----------KAAATPAKKTVTPA 101
+ + SP K+ A +P K+ A +P + K A +K +P
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 102 KAVTTPGKKGATPGKALVATPGKKGAAI--PAKGAKNGKNAKKEDSDEEEDDDSEEDEED 159
K +K +P KA +P K + + AK + K+ KE++ E S EE
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 160 DEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK 219
E E A A +P E E ++ + D EA + +
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKE-EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 220 KAAKVVPVKAKNVAEDEDEEED------DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
A P KAK+ ++E + + ED + E + ++ + +EEE+ +E V
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835
Query: 274 KEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAK 333
KE P K ++E K A P+ +++K E + K K S V AK
Sbjct: 836 KEPPKKAEEE--KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 334 NDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDAR 393
+ A ++ K E ED + + K ++ K ++P KKE
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953
Query: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTE 453
K K +++ K + + + +SK+ E + D + + ++ TE
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 73.2 bits (178), Expect = 8e-13
Identities = 105/436 (24%), Positives = 180/436 (41%), Gaps = 37/436 (8%)
Query: 25 EEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVT 84
EE+ ++EE E+EE + EE P + A S +K SP K+ A +PA+ A +
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAE----EAASPEKEAKSPVKEEA-KSPAE--AKS 532
Query: 85 PGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPA--KGAKNGKNAKK 142
P K+ A +PA + +P KA + ++ +P +A +P K+ A PA K + K+ K
Sbjct: 533 PEKEEAKSPA-EVKSPEKAKSPAKEEAKSPPEA--KSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS-EDEDDEDDEDDEDDDDD 201
E++ + S E + E+ + +K A +PA + + E+
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649
Query: 202 EEDDSEEEAMETTPAKGK---KAAKVVPVKAKN--VAEDEDEEEDDEDEDDDDDEDDEDD 256
E+ S E+ +P K K KA P KAK+ AE + E+ ++ ++
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 709
Query: 257 DDEDDEEEEEEEEEEPVKE---APGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGN 313
+E + E+ + PVKE P K K + ++ +PE K P A L V +
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK------SPEKAKTLDVKS 763
Query: 314 LNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFG 373
A E +D F + + V + K E A+ EK E+ +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK--EIPKKEEVK 821
Query: 374 NEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAY 433
+ +K E+ K ++ K + + + P +E K+ ++ A + K
Sbjct: 822 SPVK-EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK-------PK 873
Query: 434 IEFKTEADAEKTFEEK 449
+E K E EK E K
Sbjct: 874 VEEKKEPAVEKPKESK 889
Score = 68.2 bits (165), Expect = 3e-11
Identities = 74/299 (24%), Positives = 125/299 (41%), Gaps = 19/299 (6%)
Query: 14 PKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVA 73
P+K A P + E S E S ++E+ S EV P+K A + +K
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE 571
Query: 74 VATPAK----KAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAI 129
+PA+ + A +P K+ A +PA+ +P KA + ++ +P +A +P K+ A
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAK-SPEKAKSPVKEEAKSPAEA--KSPVKEEAKS 628
Query: 130 PA--KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDE----DEIEPAAMKAAAAAPA 183
PA K + K+ KE++ E S E EE E + P K+ A A
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 184 SEDEDDEDDEDDEDDDDDE-EDDSEEEAMETTPAKG--KKAAKVVPVKAKNVAEDEDEEE 240
E + +E ++ + +EEA AK K+ AK P KAK+ ++E +
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT-PEKAKSPV--KEEAK 745
Query: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVE 299
E + D + + +EE P + P K K + ++ +PE K ++
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 14/196 (7%)
Query: 2 VKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSA 61
VK+ + K + K A P E ++DS+ EE + E EE P + K + A
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEA 892
Query: 62 KKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVAT 121
KK KK V TP K+A K A P +KT K K P K
Sbjct: 893 KKEEAEDKKK--VPTPEKEAPAKVEVKEDAKPKEKTEVAKK--EPDDAKAKEPSK----- 943
Query: 122 PGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
P +K A P K K+ K+E + + E+ E + ++D+ ++ +P A KA ++
Sbjct: 944 PAEKKEAAPEK-----KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998
Query: 182 PASEDEDDEDDEDDED 197
+ + ++ ED
Sbjct: 999 STDQKDSKPPEKATED 1014
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 12/173 (6%)
Query: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197
K AK+E+ EEE + EE+ E E+E + E A+ + A +P E+ + +
Sbjct: 476 KEAKEEEGKEEEGGE-EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA-----KSPAE 529
Query: 198 DDDDEEDDSEEEAMETTPAKGKKAAK---VVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE 254
E+++++ A +P K K AK P +AK+ ++E + + + +
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 255 DDDDEDDEEEEEEEEEEPVKE---APGKRKKEMAKQKAAPEAKKQKVEGTEPT 304
++ E + E+ + PVKE +P + K + ++ +P K + PT
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 11/165 (6%)
Query: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202
E S++E E+ EE E+ E+E + A + E+E+ E E++ E
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507
Query: 203 EDDSEEEAMET-------TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255
E S E+ ++ +PA+ K K +AK+ AE + E+ ++ E
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEK---EEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 256 DDDEDDEEEEEEEEEEPVK-EAPGKRKKEMAKQKAAPEAKKQKVE 299
E +E + E + P K ++P K + + + +PE K V+
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 11/165 (6%)
Query: 153 SEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED---DEDDDDDEEDDSEEE 209
SEE + E +++ +E + +E+E+ E E+ +E+ ++EE + EE
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE 499
Query: 210 AMETTPAK-----GKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE 264
++ PA+ K+A V +AK+ AE + E+++ + ++ +E +
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 265 EEEEEEEPVKE---APGKRKKEMAKQKAAPEAKKQKVEGTEPTTA 306
E + P KE +P + K + A E K E P A
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Score = 33.9 bits (76), Expect = 0.54
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE-EEEE 271
+T K K K+ V+ EE+ +E + ++ ++E+ + +++E +EEE EEE
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEE 492
Query: 272 PVKEAPGKRKKEMAKQKAAPEAKKQ---KVEGTEPTTA 306
+ + K A++ A+PE + + K E P A
Sbjct: 493 EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA 530
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 80.5 bits (197), Expect = 5e-15
Identities = 87/395 (22%), Positives = 169/395 (42%), Gaps = 39/395 (9%)
Query: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
KED++ +E + D + EP+ K+ A+ + D E +E+
Sbjct: 128 KEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG- 186
Query: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261
ED EE ++E A K+ + + +K+K V ++E+ +D+ DE + E++
Sbjct: 187 -EDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEE 245
Query: 262 EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK---KQKVEGTEPTTAFNLFVGNLNFNK 318
+ +E + G+ + A +K PEA+ ++ EPTT + + FN
Sbjct: 246 DSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNV 305
Query: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGY--VDFESAEDLEKALELTGLKVFGNEI 376
+ + ++ + +A+ VR K GY VDF + E++++AL+ + G I
Sbjct: 306 TEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
Query: 377 KLEKPK---------------------GKDSKKE--RDARTLLAKNLPYKVTQDELKEVF 413
++ + K G++ ++E ++ L +NLPY T+++L+++F
Sbjct: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLF 422
Query: 414 EDAAEIR-----LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSIS-LYYTGEK 467
+ + S K KG A+I F A K + E G GR + L T +K
Sbjct: 423 SKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKK 482
Query: 468 GQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
++D +S++ + + +N + S TL
Sbjct: 483 EASEDASALGSSSYKKKKEAQDKANSASSHNWNTL 517
Score = 76.3 bits (186), Expect = 9e-14
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 52/272 (19%)
Query: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP 272
T P K K K+ AE E + + ED++ E+ D+ EEEEEEEEEE
Sbjct: 665 TAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEE 724
Query: 273 VKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFA 332
E LF+ NLNF+ + +LK S V
Sbjct: 725 -----------------------------ESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
Query: 333 KNDLAVVDVR----IGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKLE------KP 381
++ + + ++ FG+V++ E +KAL +L G V G+++++ KP
Sbjct: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
Query: 382 -----KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV------SKDGKSKG 430
+ K +++ +L +N+P++ E++E+F E++ V + G +G
Sbjct: 816 AVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRG 875
Query: 431 IAYIEFKTEADAEKTFEEK-QGTEIDGRSISL 461
+++F T+ DA++ F T + GR + L
Sbjct: 876 FGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 21/180 (11%)
Query: 487 TLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSK-------GYAFIEFASFEDAKEA 539
TL + NL++ TEE L+EVF K +K K+K G+ F+E+ E A++A
Sbjct: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
Query: 540 LNSCNKREIEGRAIRLELQGPRGSPNA---------RSQPSKTLFVKGLSEDTTEETLKE 590
L ++G + + + P R Q + + V+ + ++E
Sbjct: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
Query: 591 SFD--GSVRARIVTDRETGSS--KGFGFVDFNSEEDAKAAKEAM-EDGEIDGNKVTLDWA 645
F G ++ + + TG+ +GFGFVDF +++DAK A A+ + G ++ L+WA
Sbjct: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWA 910
Score = 67.8 bits (164), Expect = 3e-11
Identities = 46/197 (23%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 377 KLEKPKGKDSKKERDAR--TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGK------- 427
K+E+ + ++ ++E TL KNL + T+++LKEVF ++ S K
Sbjct: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
Query: 428 -SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESK 486
S G ++E++ A+K ++ QG +DG + + + + K ++
Sbjct: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
Query: 487 TLVL-SNLSYSATEETLQEVFE---KATFIKVPQNQNGKS--KGYAFIEFASFEDAKEAL 540
+ +L N+ + A ++E+F + +++P+ G +G+ F++F + +DAK A
Sbjct: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAF 891
Query: 541 NS-CNKREIEGRAIRLE 556
N+ C+ + GR + LE
Sbjct: 892 NALCHSTHLYGRRLVLE 908
Score = 55.5 bits (132), Expect = 2e-07
Identities = 94/402 (23%), Positives = 157/402 (39%), Gaps = 57/402 (14%)
Query: 263 EEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPE 322
++ + ++ P + KK+ K+K A + +K K + T F F L+ ++ +
Sbjct: 94 QKPSQPKQPPKDSTTPEIKKDEKKKKVAGQLEKLKED-----TEFQEF---LSVHQRRAQ 145
Query: 323 LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPK 382
T +A + L + Y++F+S E E G + E LE PK
Sbjct: 146 AAT-----WANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG-EDLEEEASLE-PK 198
Query: 383 GKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADA 442
K+ D L +K + + +E ED A + + + + E D+
Sbjct: 199 AAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDS 258
Query: 443 EKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
+ +E+ R EK NQ K T T+ L ++ TE+ +
Sbjct: 259 KGAGQEQGMPAGKKRPPEARAETEKPANQ-----KEPT---TCHTVKLRGAPFNVTEKNV 310
Query: 503 QEVFE--KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGP 560
E K I++ +N +G GY F++F++ E+ K+AL CN+ + GR I E+
Sbjct: 311 MEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYI--EVFRE 367
Query: 561 RGSPNARSQPSKT-----------------------LFVKGLSEDTTEETLKESFD--GS 595
+ P + P T LFV+ L +TEE L++ F G
Sbjct: 368 KNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGP 427
Query: 596 V-RARIVTDRETGSSKGFGFVDFNSEEDA-KAAKEAMEDGEI 635
+ D T KGF F+ F E A KA E DG++
Sbjct: 428 LSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV--DGQV 467
Score = 54.3 bits (129), Expect = 4e-07
Identities = 31/98 (31%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRET 606
+ + ++E + S P TLF+K L+ DTTEE LKE F G+V++ ++ ++
Sbjct: 707 DNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKN 766
Query: 607 GS----SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640
+ S GFGFV++ E A+ A + ++ +DG+K+
Sbjct: 767 KAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL 804
Score = 53.1 bits (126), Expect = 9e-07
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 25/203 (12%)
Query: 375 EIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDA--AEIRLV-SKDGKSKGI 431
E + E K + K+ T+ + P+ VT+ + E IR+V + G G
Sbjct: 276 EARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGY 335
Query: 432 AYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST--WSG------ 483
+++F E + ++ + + + GR I ++ EK KN+T W G
Sbjct: 336 IFVDFSNEEEVKQALKCNR-EYMGGRYIEVFR--EKNVPTTKGAPKNTTKSWQGRILGEN 392
Query: 484 -------ESKTLVLSNLSYSATEETLQEVFEK---ATFIKVP-QNQNGKSKGYAFIEFAS 532
ES L + NL Y++TEE L+++F K + + P + K KG+AFI F
Sbjct: 393 EEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMF 452
Query: 533 FEDAKEALNSCNKREIEGRAIRL 555
E A +A + + + +GR + +
Sbjct: 453 PEHAVKAYSEVDGQVFQGRMLHV 475
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 574 LFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME 631
L VK L EE ++ F G++ + + G + FGF+ F SEE+A+ A++
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 632 DGEIDGNKVTLDWAKPKGE 650
ID +++T+++ K G+
Sbjct: 64 KSFIDTSRITVEFCKSFGD 82
Score = 35.8 bits (81), Expect = 0.14
Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 43/266 (16%)
Query: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
A K + S+ E D +E + D + EDE+ E A ++A E+E++E++E
Sbjct: 666 APQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEE 725
Query: 194 DDED----DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
+ D +EE+ E +KV VK+ ++++ +++
Sbjct: 726 SLPGCTLFIKNLNFDTTEEKLKEV-------FSKVGTVKSCSISKKKNKAGVLLSMGFG- 777
Query: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGK---------RKKEMAKQKAAPEAKKQKVEG 300
E + E+ ++ +K+ G R E A + A A+K++V
Sbjct: 778 ----------FVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPR 827
Query: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT-----RKFGYVDFE 355
+ T+ + V N+ F + E++ S +L V + MT R FG+VDF
Sbjct: 828 KQTTS--KILVRNIPFQAHSREIRELFSTF---GELKTVRLPKKMTGTGTHRGFGFVDFL 882
Query: 356 SAEDLEKALELT--GLKVFGNEIKLE 379
+ +D ++A ++G + LE
Sbjct: 883 TKQDAKRAFNALCHSTHLYGRRLVLE 908
Score = 34.3 bits (77), Expect = 0.41
Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 26/280 (9%)
Query: 395 LLAKNLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQ 450
L+ KNLP + ++ +++F + S KDGK + +I FK+E +A+K +
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 451 GTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKAT 510
+ ID I++ + G K WS ++ S + T E+ +
Sbjct: 64 KSFIDTSRITVEFCKSFGD-----PAKPRAWSKHAQK--PSQPKQPPKDSTTPEIKKDEK 116
Query: 511 FIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQP 570
KV + F EF S + + ++ + + + N S
Sbjct: 117 KKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDS 176
Query: 571 SKTLFVKGLSEDTTEETLKE---------SFDGSVRARIVTDRETGSSKGFGFVDFNSEE 621
+ +G ED EE E S +++++V + SS+ + SE+
Sbjct: 177 GQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSE-----EEESED 231
Query: 622 DAKAAKEAMEDGEIDGNKV-TLDWAKPKGEGGFGGRGGGR 660
+A E E E D + L KG G G G+
Sbjct: 232 EAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGK 271
Score = 32.3 bits (72), Expect = 1.6
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 116 KALVATPGKKGAAIPAKG--AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP 172
K L TP + PA+ +G+ + E+ EE D+S E++E+E+E+E+E P
Sbjct: 670 KKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLP 728
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 80.5 bits (197), Expect = 5e-15
Identities = 87/395 (22%), Positives = 169/395 (42%), Gaps = 39/395 (9%)
Query: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
KED++ +E + D + EP+ K+ A+ + D E +E+
Sbjct: 128 KEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG- 186
Query: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261
ED EE ++E A K+ + + +K+K V ++E+ +D+ DE + E++
Sbjct: 187 -EDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEE 245
Query: 262 EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK---KQKVEGTEPTTAFNLFVGNLNFNK 318
+ +E + G+ + A +K PEA+ ++ EPTT + + FN
Sbjct: 246 DSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNV 305
Query: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGY--VDFESAEDLEKALELTGLKVFGNEI 376
+ + ++ + +A+ VR K GY VDF + E++++AL+ + G I
Sbjct: 306 TEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
Query: 377 KLEKPK---------------------GKDSKKE--RDARTLLAKNLPYKVTQDELKEVF 413
++ + K G++ ++E ++ L +NLPY T+++L+++F
Sbjct: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLF 422
Query: 414 EDAAEIR-----LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSIS-LYYTGEK 467
+ + S K KG A+I F A K + E G GR + L T +K
Sbjct: 423 SKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKK 482
Query: 468 GQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
++D +S++ + + +N + S TL
Sbjct: 483 EASEDASALGSSSYKKKKEAQDKANSASSHNWNTL 517
Score = 76.3 bits (186), Expect = 9e-14
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 52/272 (19%)
Query: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP 272
T P K K K+ AE E + + ED++ E+ D+ EEEEEEEEEE
Sbjct: 665 TAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEE 724
Query: 273 VKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFA 332
E LF+ NLNF+ + +LK S V
Sbjct: 725 -----------------------------ESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
Query: 333 KNDLAVVDVR----IGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKLE------KP 381
++ + + ++ FG+V++ E +KAL +L G V G+++++ KP
Sbjct: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
Query: 382 -----KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV------SKDGKSKG 430
+ K +++ +L +N+P++ E++E+F E++ V + G +G
Sbjct: 816 AVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRG 875
Query: 431 IAYIEFKTEADAEKTFEEK-QGTEIDGRSISL 461
+++F T+ DA++ F T + GR + L
Sbjct: 876 FGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 21/180 (11%)
Query: 487 TLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSK-------GYAFIEFASFEDAKEA 539
TL + NL++ TEE L+EVF K +K K+K G+ F+E+ E A++A
Sbjct: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
Query: 540 LNSCNKREIEGRAIRLELQGPRGSPNA---------RSQPSKTLFVKGLSEDTTEETLKE 590
L ++G + + + P R Q + + V+ + ++E
Sbjct: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
Query: 591 SFD--GSVRARIVTDRETGSS--KGFGFVDFNSEEDAKAAKEAM-EDGEIDGNKVTLDWA 645
F G ++ + + TG+ +GFGFVDF +++DAK A A+ + G ++ L+WA
Sbjct: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWA 910
Score = 67.8 bits (164), Expect = 3e-11
Identities = 46/197 (23%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 377 KLEKPKGKDSKKERDAR--TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGK------- 427
K+E+ + ++ ++E TL KNL + T+++LKEVF ++ S K
Sbjct: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
Query: 428 -SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESK 486
S G ++E++ A+K ++ QG +DG + + + + K ++
Sbjct: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
Query: 487 TLVL-SNLSYSATEETLQEVFE---KATFIKVPQNQNGKS--KGYAFIEFASFEDAKEAL 540
+ +L N+ + A ++E+F + +++P+ G +G+ F++F + +DAK A
Sbjct: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAF 891
Query: 541 NS-CNKREIEGRAIRLE 556
N+ C+ + GR + LE
Sbjct: 892 NALCHSTHLYGRRLVLE 908
Score = 55.5 bits (132), Expect = 2e-07
Identities = 94/402 (23%), Positives = 157/402 (39%), Gaps = 57/402 (14%)
Query: 263 EEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPE 322
++ + ++ P + KK+ K+K A + +K K + T F F L+ ++ +
Sbjct: 94 QKPSQPKQPPKDSTTPEIKKDEKKKKVAGQLEKLKED-----TEFQEF---LSVHQRRAQ 145
Query: 323 LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPK 382
T +A + L + Y++F+S E E G + E LE PK
Sbjct: 146 AAT-----WANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG-EDLEEEASLE-PK 198
Query: 383 GKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADA 442
K+ D L +K + + +E ED A + + + + E D+
Sbjct: 199 AAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDS 258
Query: 443 EKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
+ +E+ R EK NQ K T T+ L ++ TE+ +
Sbjct: 259 KGAGQEQGMPAGKKRPPEARAETEKPANQ-----KEPT---TCHTVKLRGAPFNVTEKNV 310
Query: 503 QEVFE--KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGP 560
E K I++ +N +G GY F++F++ E+ K+AL CN+ + GR I E+
Sbjct: 311 MEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYI--EVFRE 367
Query: 561 RGSPNARSQPSKT-----------------------LFVKGLSEDTTEETLKESFD--GS 595
+ P + P T LFV+ L +TEE L++ F G
Sbjct: 368 KNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGP 427
Query: 596 V-RARIVTDRETGSSKGFGFVDFNSEEDA-KAAKEAMEDGEI 635
+ D T KGF F+ F E A KA E DG++
Sbjct: 428 LSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV--DGQV 467
Score = 54.3 bits (129), Expect = 4e-07
Identities = 31/98 (31%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRET 606
+ + ++E + S P TLF+K L+ DTTEE LKE F G+V++ ++ ++
Sbjct: 707 DNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKN 766
Query: 607 GS----SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640
+ S GFGFV++ E A+ A + ++ +DG+K+
Sbjct: 767 KAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL 804
Score = 53.1 bits (126), Expect = 9e-07
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 25/203 (12%)
Query: 375 EIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDA--AEIRLV-SKDGKSKGI 431
E + E K + K+ T+ + P+ VT+ + E IR+V + G G
Sbjct: 276 EARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGY 335
Query: 432 AYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST--WSG------ 483
+++F E + ++ + + + GR I ++ EK KN+T W G
Sbjct: 336 IFVDFSNEEEVKQALKCNR-EYMGGRYIEVFR--EKNVPTTKGAPKNTTKSWQGRILGEN 392
Query: 484 -------ESKTLVLSNLSYSATEETLQEVFEK---ATFIKVP-QNQNGKSKGYAFIEFAS 532
ES L + NL Y++TEE L+++F K + + P + K KG+AFI F
Sbjct: 393 EEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMF 452
Query: 533 FEDAKEALNSCNKREIEGRAIRL 555
E A +A + + + +GR + +
Sbjct: 453 PEHAVKAYSEVDGQVFQGRMLHV 475
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 574 LFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME 631
L VK L EE ++ F G++ + + G + FGF+ F SEE+A+ A++
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 632 DGEIDGNKVTLDWAKPKGE 650
ID +++T+++ K G+
Sbjct: 64 KSFIDTSRITVEFCKSFGD 82
Score = 35.8 bits (81), Expect = 0.14
Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 43/266 (16%)
Query: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
A K + S+ E D +E + D + EDE+ E A ++A E+E++E++E
Sbjct: 666 APQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEE 725
Query: 194 DDED----DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
+ D +EE+ E +KV VK+ ++++ +++
Sbjct: 726 SLPGCTLFIKNLNFDTTEEKLKEV-------FSKVGTVKSCSISKKKNKAGVLLSMGFG- 777
Query: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGK---------RKKEMAKQKAAPEAKKQKVEG 300
E + E+ ++ +K+ G R E A + A A+K++V
Sbjct: 778 ----------FVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPR 827
Query: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT-----RKFGYVDFE 355
+ T+ + V N+ F + E++ S +L V + MT R FG+VDF
Sbjct: 828 KQTTS--KILVRNIPFQAHSREIRELFSTF---GELKTVRLPKKMTGTGTHRGFGFVDFL 882
Query: 356 SAEDLEKALELT--GLKVFGNEIKLE 379
+ +D ++A ++G + LE
Sbjct: 883 TKQDAKRAFNALCHSTHLYGRRLVLE 908
Score = 34.3 bits (77), Expect = 0.41
Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 26/280 (9%)
Query: 395 LLAKNLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQ 450
L+ KNLP + ++ +++F + S KDGK + +I FK+E +A+K +
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 451 GTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKAT 510
+ ID I++ + G K WS ++ S + T E+ +
Sbjct: 64 KSFIDTSRITVEFCKSFGD-----PAKPRAWSKHAQK--PSQPKQPPKDSTTPEIKKDEK 116
Query: 511 FIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQP 570
KV + F EF S + + ++ + + + N S
Sbjct: 117 KKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDS 176
Query: 571 SKTLFVKGLSEDTTEETLKE---------SFDGSVRARIVTDRETGSSKGFGFVDFNSEE 621
+ +G ED EE E S +++++V + SS+ + SE+
Sbjct: 177 GQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSE-----EEESED 231
Query: 622 DAKAAKEAMEDGEIDGNKV-TLDWAKPKGEGGFGGRGGGR 660
+A E E E D + L KG G G G+
Sbjct: 232 EAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGK 271
Score = 32.3 bits (72), Expect = 1.6
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 116 KALVATPGKKGAAIPAKG--AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP 172
K L TP + PA+ +G+ + E+ EE D+S E++E+E+E+E+E P
Sbjct: 670 KKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLP 728
>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 80.5 bits (197), Expect = 5e-15
Identities = 87/395 (22%), Positives = 169/395 (42%), Gaps = 39/395 (9%)
Query: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
KED++ +E + D + EP+ K+ A+ + D E +E+
Sbjct: 128 KEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG- 186
Query: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261
ED EE ++E A K+ + + +K+K V ++E+ +D+ DE + E++
Sbjct: 187 -EDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEE 245
Query: 262 EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK---KQKVEGTEPTTAFNLFVGNLNFNK 318
+ +E + G+ + A +K PEA+ ++ EPTT + + FN
Sbjct: 246 DSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNV 305
Query: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGY--VDFESAEDLEKALELTGLKVFGNEI 376
+ + ++ + +A+ VR K GY VDF + E++++AL+ + G I
Sbjct: 306 TEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
Query: 377 KLEKPK---------------------GKDSKKE--RDARTLLAKNLPYKVTQDELKEVF 413
++ + K G++ ++E ++ L +NLPY T+++L+++F
Sbjct: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLF 422
Query: 414 EDAAEIR-----LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSIS-LYYTGEK 467
+ + S K KG A+I F A K + E G GR + L T +K
Sbjct: 423 SKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKK 482
Query: 468 GQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
++D +S++ + + +N + S TL
Sbjct: 483 EASEDASALGSSSYKKKKEAQDKANSASSHNWNTL 517
Score = 76.3 bits (186), Expect = 9e-14
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 52/272 (19%)
Query: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP 272
T P K K K+ AE E + + ED++ E+ D+ EEEEEEEEEE
Sbjct: 665 TAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEE 724
Query: 273 VKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFA 332
E LF+ NLNF+ + +LK S V
Sbjct: 725 -----------------------------ESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
Query: 333 KNDLAVVDVR----IGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKLE------KP 381
++ + + ++ FG+V++ E +KAL +L G V G+++++ KP
Sbjct: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
Query: 382 -----KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV------SKDGKSKG 430
+ K +++ +L +N+P++ E++E+F E++ V + G +G
Sbjct: 816 AVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRG 875
Query: 431 IAYIEFKTEADAEKTFEEK-QGTEIDGRSISL 461
+++F T+ DA++ F T + GR + L
Sbjct: 876 FGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 21/180 (11%)
Query: 487 TLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSK-------GYAFIEFASFEDAKEA 539
TL + NL++ TEE L+EVF K +K K+K G+ F+E+ E A++A
Sbjct: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
Query: 540 LNSCNKREIEGRAIRLELQGPRGSPNA---------RSQPSKTLFVKGLSEDTTEETLKE 590
L ++G + + + P R Q + + V+ + ++E
Sbjct: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
Query: 591 SFD--GSVRARIVTDRETGSS--KGFGFVDFNSEEDAKAAKEAM-EDGEIDGNKVTLDWA 645
F G ++ + + TG+ +GFGFVDF +++DAK A A+ + G ++ L+WA
Sbjct: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWA 910
Score = 67.8 bits (164), Expect = 3e-11
Identities = 46/197 (23%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 377 KLEKPKGKDSKKERDAR--TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGK------- 427
K+E+ + ++ ++E TL KNL + T+++LKEVF ++ S K
Sbjct: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
Query: 428 -SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESK 486
S G ++E++ A+K ++ QG +DG + + + + K ++
Sbjct: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
Query: 487 TLVL-SNLSYSATEETLQEVFE---KATFIKVPQNQNGKS--KGYAFIEFASFEDAKEAL 540
+ +L N+ + A ++E+F + +++P+ G +G+ F++F + +DAK A
Sbjct: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAF 891
Query: 541 NS-CNKREIEGRAIRLE 556
N+ C+ + GR + LE
Sbjct: 892 NALCHSTHLYGRRLVLE 908
Score = 55.5 bits (132), Expect = 2e-07
Identities = 94/402 (23%), Positives = 157/402 (39%), Gaps = 57/402 (14%)
Query: 263 EEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPE 322
++ + ++ P + KK+ K+K A + +K K + T F F L+ ++ +
Sbjct: 94 QKPSQPKQPPKDSTTPEIKKDEKKKKVAGQLEKLKED-----TEFQEF---LSVHQRRAQ 145
Query: 323 LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPK 382
T +A + L + Y++F+S E E G + E LE PK
Sbjct: 146 AAT-----WANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG-EDLEEEASLE-PK 198
Query: 383 GKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADA 442
K+ D L +K + + +E ED A + + + + E D+
Sbjct: 199 AAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDS 258
Query: 443 EKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
+ +E+ R EK NQ K T T+ L ++ TE+ +
Sbjct: 259 KGAGQEQGMPAGKKRPPEARAETEKPANQ-----KEPT---TCHTVKLRGAPFNVTEKNV 310
Query: 503 QEVFE--KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGP 560
E K I++ +N +G GY F++F++ E+ K+AL CN+ + GR I E+
Sbjct: 311 MEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYI--EVFRE 367
Query: 561 RGSPNARSQPSKT-----------------------LFVKGLSEDTTEETLKESFD--GS 595
+ P + P T LFV+ L +TEE L++ F G
Sbjct: 368 KNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGP 427
Query: 596 V-RARIVTDRETGSSKGFGFVDFNSEEDA-KAAKEAMEDGEI 635
+ D T KGF F+ F E A KA E DG++
Sbjct: 428 LSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV--DGQV 467
Score = 54.3 bits (129), Expect = 4e-07
Identities = 31/98 (31%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRET 606
+ + ++E + S P TLF+K L+ DTTEE LKE F G+V++ ++ ++
Sbjct: 707 DNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKN 766
Query: 607 GS----SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640
+ S GFGFV++ E A+ A + ++ +DG+K+
Sbjct: 767 KAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL 804
Score = 53.1 bits (126), Expect = 9e-07
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 25/203 (12%)
Query: 375 EIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDA--AEIRLV-SKDGKSKGI 431
E + E K + K+ T+ + P+ VT+ + E IR+V + G G
Sbjct: 276 EARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGY 335
Query: 432 AYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST--WSG------ 483
+++F E + ++ + + + GR I ++ EK KN+T W G
Sbjct: 336 IFVDFSNEEEVKQALKCNR-EYMGGRYIEVFR--EKNVPTTKGAPKNTTKSWQGRILGEN 392
Query: 484 -------ESKTLVLSNLSYSATEETLQEVFEK---ATFIKVP-QNQNGKSKGYAFIEFAS 532
ES L + NL Y++TEE L+++F K + + P + K KG+AFI F
Sbjct: 393 EEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMF 452
Query: 533 FEDAKEALNSCNKREIEGRAIRL 555
E A +A + + + +GR + +
Sbjct: 453 PEHAVKAYSEVDGQVFQGRMLHV 475
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 574 LFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME 631
L VK L EE ++ F G++ + + G + FGF+ F SEE+A+ A++
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 632 DGEIDGNKVTLDWAKPKGE 650
ID +++T+++ K G+
Sbjct: 64 KSFIDTSRITVEFCKSFGD 82
Score = 35.8 bits (81), Expect = 0.14
Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 43/266 (16%)
Query: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
A K + S+ E D +E + D + EDE+ E A ++A E+E++E++E
Sbjct: 666 APQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEE 725
Query: 194 DDED----DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
+ D +EE+ E +KV VK+ ++++ +++
Sbjct: 726 SLPGCTLFIKNLNFDTTEEKLKEV-------FSKVGTVKSCSISKKKNKAGVLLSMGFG- 777
Query: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGK---------RKKEMAKQKAAPEAKKQKVEG 300
E + E+ ++ +K+ G R E A + A A+K++V
Sbjct: 778 ----------FVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPR 827
Query: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT-----RKFGYVDFE 355
+ T+ + V N+ F + E++ S +L V + MT R FG+VDF
Sbjct: 828 KQTTS--KILVRNIPFQAHSREIRELFSTF---GELKTVRLPKKMTGTGTHRGFGFVDFL 882
Query: 356 SAEDLEKALELT--GLKVFGNEIKLE 379
+ +D ++A ++G + LE
Sbjct: 883 TKQDAKRAFNALCHSTHLYGRRLVLE 908
Score = 34.3 bits (77), Expect = 0.41
Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 26/280 (9%)
Query: 395 LLAKNLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQ 450
L+ KNLP + ++ +++F + S KDGK + +I FK+E +A+K +
Sbjct: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
Query: 451 GTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKAT 510
+ ID I++ + G K WS ++ S + T E+ +
Sbjct: 64 KSFIDTSRITVEFCKSFGD-----PAKPRAWSKHAQK--PSQPKQPPKDSTTPEIKKDEK 116
Query: 511 FIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQP 570
KV + F EF S + + ++ + + + N S
Sbjct: 117 KKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDS 176
Query: 571 SKTLFVKGLSEDTTEETLKE---------SFDGSVRARIVTDRETGSSKGFGFVDFNSEE 621
+ +G ED EE E S +++++V + SS+ + SE+
Sbjct: 177 GQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSE-----EEESED 231
Query: 622 DAKAAKEAMEDGEIDGNKV-TLDWAKPKGEGGFGGRGGGR 660
+A E E E D + L KG G G G+
Sbjct: 232 EAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGK 271
Score = 32.3 bits (72), Expect = 1.6
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 116 KALVATPGKKGAAIPAKG--AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP 172
K L TP + PA+ +G+ + E+ EE D+S E++E+E+E+E+E P
Sbjct: 670 KKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLP 728
>gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c
[Homo sapiens]
Length = 306
Score = 80.1 bits (196), Expect = 7e-15
Identities = 69/247 (27%), Positives = 108/247 (43%), Gaps = 22/247 (8%)
Query: 448 EKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFE 507
E +G +ID S E N R + +T E + + LS+ T++ L++ F
Sbjct: 62 ESEGAKIDA---SKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118
Query: 508 KATFIKVPQNQ------NGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPR 561
K F +V G+S+G+ F+ F E + ++ + ++ G+ I R
Sbjct: 119 K--FGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ-KEHKLNGKVI----DPKR 171
Query: 562 GSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIV---TDRETGSSKGFGFVDFN 618
+P K +FV GLS DT EE ++E F G + D +T +GF F+ F
Sbjct: 172 AKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFK 231
Query: 619 SEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGG--RGGF 676
EE K E + + +K + A K + + G RGGF GR GRGG + G+
Sbjct: 232 EEEPVKKIME-KKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGY 290
Query: 677 GGRGRGG 683
G R G
Sbjct: 291 GKVSRRG 297
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 79.7 bits (195), Expect = 9e-15
Identities = 69/257 (26%), Positives = 108/257 (42%), Gaps = 25/257 (9%)
Query: 465 GEKGQNQDYRGGKNSTWSGESKT--LVLSNLSYSATEETLQEVFEKATFIKVPQNQ---- 518
G +G + + G K E + + LS+ T++ L++ F K F +V
Sbjct: 55 GTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSK--FGEVVDCTLKLD 112
Query: 519 --NGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFV 576
G+S+G+ F+ F E + ++ + ++ G+ I R +P K +FV
Sbjct: 113 PITGRSRGFGFVLFKESESVDKVMDQ-KEHKLNGKVI----DPKRAKAMKTKEPVKKIFV 167
Query: 577 KGLSEDTTEETLKESFDGSVRARIV---TDRETGSSKGFGFVDFNSEEDAKAAKEAMEDG 633
GLS DT EE ++E F G + D +T +GF F+ F EE K E +
Sbjct: 168 GGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIME-KKYH 226
Query: 634 EIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGG------RGGFGGRGRGGFGGR 687
+ +K + A K + + G RGGF GR GRGG G+ G+G
Sbjct: 227 NVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNY 286
Query: 688 GGFRGGRGGGGDHKPQG 704
G G GG G + G
Sbjct: 287 GYNSQGYGGYGGYDYTG 303
Score = 49.3 bits (116), Expect = 1e-05
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 22/177 (12%)
Query: 373 GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI-----RLVSKDGK 427
G + E K SK E D + L + T+ +LK+ F E+ +L G+
Sbjct: 58 GGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGR 117
Query: 428 SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKT 487
S+G ++ FK +K ++K+ +++G+ I D + K K
Sbjct: 118 SRGFGFVLFKESESVDKVMDQKE-HKLNGKVI------------DPKRAKAMKTKEPVKK 164
Query: 488 LVLSNLSYSATEETLQEV---FEKATFIKVP-QNQNGKSKGYAFIEFASFEDAKEAL 540
+ + LS EE ++E F + I++P N+ K +G+ FI F E K+ +
Sbjct: 165 IFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.127 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,214,314
Number of Sequences: 37866
Number of extensions: 2039777
Number of successful extensions: 130189
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1895
Number of HSP's successfully gapped in prelim test: 942
Number of HSP's that attempted gapping in prelim test: 21830
Number of HSP's gapped (non-prelim): 39783
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.