BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo sapiens] (1214 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo... 2460 0.0 gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo... 2403 0.0 gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m... 676 0.0 gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens] 620 e-177 gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] 281 3e-75 gi|41152506 prostaglandin F2 receptor negative regulator [Homo s... 245 2e-64 gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m... 240 7e-63 gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens] 240 7e-63 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 61 6e-09 gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens] 46 2e-04 gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo sapi... 46 2e-04 gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens] 45 3e-04 gi|31377806 polymeric immunoglobulin receptor precursor [Homo sa... 45 4e-04 gi|110349719 titin isoform N2-A [Homo sapiens] 44 7e-04 gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo ... 43 0.002 gi|14150145 matrix-remodelling associated 8 [Homo sapiens] 42 0.003 gi|45331217 zinc finger protein 526 [Homo sapiens] 42 0.005 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 41 0.006 gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.008 gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] 40 0.013 gi|21735415 centromere protein B [Homo sapiens] 40 0.013 gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 40 0.013 gi|55953110 retinoblastoma protein-binding zinc finger protein i... 40 0.018 gi|20336260 retinoblastoma protein-binding zinc finger protein i... 40 0.018 gi|20336258 retinoblastoma protein-binding zinc finger protein i... 40 0.018 gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 40 0.018 gi|144226847 obscurin-like 1 [Homo sapiens] 39 0.023 gi|239753214 PREDICTED: similar to hCG2043206 [Homo sapiens] 39 0.023 gi|169163270 PREDICTED: similar to hCG2043206 [Homo sapiens] 39 0.023 gi|9624969 butyrophilin-like 2 [Homo sapiens] 39 0.030 >gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo sapiens] Length = 1214 Score = 2460 bits (6375), Expect = 0.0 Identities = 1214/1214 (100%), Positives = 1214/1214 (100%) Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY Sbjct: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60 Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC Sbjct: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS Sbjct: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 Query: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD Sbjct: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240 Query: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF Sbjct: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300 Query: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV Sbjct: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360 Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQ 420 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQ Sbjct: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQ 420 Query: 421 LLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 480 LLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI Sbjct: 421 LLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 480 Query: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 540 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV Sbjct: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 540 Query: 541 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 600 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV Sbjct: 541 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 600 Query: 601 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 660 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA Sbjct: 601 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 660 Query: 661 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 720 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN Sbjct: 661 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 720 Query: 721 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV Sbjct: 721 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780 Query: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 840 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS Sbjct: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 840 Query: 841 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 900 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE Sbjct: 841 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 900 Query: 901 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 960 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG Sbjct: 901 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 960 Query: 961 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1020 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK Sbjct: 961 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1020 Query: 1021 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1080 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP Sbjct: 1021 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1080 Query: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1140 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC Sbjct: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1140 Query: 1141 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1200 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC Sbjct: 1141 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1200 Query: 1201 LEPPVLSIHPGAID 1214 LEPPVLSIHPGAID Sbjct: 1201 LEPPVLSIHPGAID 1214 >gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo sapiens] Length = 1194 Score = 2403 bits (6227), Expect = 0.0 Identities = 1193/1214 (98%), Positives = 1194/1214 (98%), Gaps = 20/1214 (1%) Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY Sbjct: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60 Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC Sbjct: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS Sbjct: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 Query: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD Sbjct: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240 Query: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF Sbjct: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300 Query: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV Sbjct: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360 Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQ 420 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPL Sbjct: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPL------------- 407 Query: 421 LLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 480 +SSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI Sbjct: 408 -------KSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 460 Query: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 540 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV Sbjct: 461 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 520 Query: 541 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 600 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV Sbjct: 521 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 580 Query: 601 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 660 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA Sbjct: 581 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 640 Query: 661 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 720 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN Sbjct: 641 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 700 Query: 721 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV Sbjct: 701 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 760 Query: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 840 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS Sbjct: 761 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 820 Query: 841 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 900 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE Sbjct: 821 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 880 Query: 901 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 960 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG Sbjct: 881 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 940 Query: 961 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1020 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK Sbjct: 941 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1000 Query: 1021 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1080 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP Sbjct: 1001 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1060 Query: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1140 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC Sbjct: 1061 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1120 Query: 1141 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1200 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC Sbjct: 1121 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1180 Query: 1201 LEPPVLSIHPGAID 1214 LEPPVLSIHPGAID Sbjct: 1181 LEPPVLSIHPGAID 1194 >gi|239753216 PREDICTED: similar to immunoglobulin superfamily, member 3 [Homo sapiens] Length = 376 Score = 676 bits (1744), Expect = 0.0 Identities = 342/375 (91%), Positives = 345/375 (92%), Gaps = 20/375 (5%) Query: 187 KVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 246 KVGEKPVEVISLSRDFMLHS SEYA RQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC Sbjct: 20 KVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 79 Query: 247 EAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEA 306 EAAEWIQ+PDGSWYAMTRKRSEGAVVNVQPT+KEFTVRLETEKRLH VGEPVEFRCI EA Sbjct: 80 EAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEA 139 Query: 307 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHL 366 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL VAKESDSVFVLKIYHL Sbjct: 140 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199 Query: 367 RQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGH 426 RQEDSGKYNCRVTEREKTVTGEFIDKESK PKNIPIIVLP Sbjct: 200 RQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLP-------------------- 239 Query: 427 LESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRD 486 LESSISVEVASNASVILEGEDLRFSCSVR AGRPQGRFSVIWQLVDRQNRRS+IMWLDRD Sbjct: 240 LESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRD 299 Query: 487 GTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI 546 GTVQPGSSYWERSSFG VQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR VDGEWQI Sbjct: 300 GTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQI 359 Query: 547 VGERRASTPISITAL 561 VGERRASTPISI AL Sbjct: 360 VGERRASTPISIIAL 374 Score = 99.0 bits (245), Expect = 2e-20 Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 42/350 (12%) Query: 785 FSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQG 844 F LT+ + SD G +YC EW+ +P+ +WY + + S V V+ + + Sbjct: 62 FRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETE 121 Query: 845 NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAK 904 + V+ C+ + V W +A + +A + A Sbjct: 122 KRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF------NSSLIATMGPNAVPVLNSEFAH 175 Query: 905 NNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTAL 964 +G+L++ S V+ L I ++ +DSG Y+C V E + +G + + + Sbjct: 176 REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPI 235 Query: 965 TVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSP 1024 V+ ++S+ V+ + + E + CS+ RF+V W + Sbjct: 236 IVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLV----------- 284 Query: 1025 GLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWE----GRLRFQRLSP 1080 D R+ ++ + D P S WE G ++ +++ P Sbjct: 285 --------------------DRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQP 324 Query: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE-SAPIGIRVL 1129 + L + + +D G Y CHV EW+ EW + E S PI I L Sbjct: 325 NSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374 Score = 98.2 bits (243), Expect = 4e-20 Identities = 82/342 (23%), Positives = 146/342 (42%), Gaps = 30/342 (8%) Query: 84 YTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMN----- 138 Y R G++ ++++ + L I LQ D GE+ C + GS+ A Sbjct: 43 YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102 Query: 139 --LVVIPDSLQTTAMPQTLHRVEQ--DPLELTCEVASETIQHSHLSVAW-----LRQKVG 189 + V P + T +T R+ +P+E C ++ + + +V+W L +G Sbjct: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMG 162 Query: 190 EKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAA 249 V V+ +SE+A R++ G++ + K + F L I+HL+ D G++ C Sbjct: 163 PNAVPVL----------NSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVT 212 Query: 250 EWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309 E + G + K + + V P + +V + + + GE + F C + Sbjct: 213 EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGR 272 Query: 310 PDRYFAVSWAF-----NSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIY 364 P F+V W S I + + S + R + G +++ + + F L I+ Sbjct: 273 PQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332 Query: 365 HLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVL 405 + R+ED G+Y C VTE + V GE+ I E + I II L Sbjct: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374 Score = 92.4 bits (228), Expect = 2e-18 Identities = 77/348 (22%), Positives = 144/348 (41%), Gaps = 20/348 (5%) Query: 480 IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRA 539 ++ L RD + GS Y R S G V+++++ +F L IF+ + D+G++ C EW++ Sbjct: 28 VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87 Query: 540 VDGEWQIVGERRAS-TPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 598 DG W + +R+ +++ E F V + + + +CI + Sbjct: 88 PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYF 147 Query: 599 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFR-TRTAIEKAESSNNVR-LSISRAS 656 +V+W F L+ V + + R R + A+ S++V L I Sbjct: 148 AVSWAFNS-------SLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLR 200 Query: 657 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 716 ++GKY C K + + + I VL + + V + ++E + Sbjct: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260 Query: 717 IQLNCSVKSQTSQNSHFAVLWYV----HKPSDADGKLILKTTHNSAFEYGTYAEEEGLRA 772 ++ +CSV+ F+V+W + ++ SD I+ + + G+ E Sbjct: 261 LRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSD-----IMWLDRDGTVQPGSSYWERSSFG 315 Query: 773 RLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAE 820 +Q E+ V FSL + + D G Y CHV EW+ + W + E Sbjct: 316 SVQMEQ-VQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGE 362 Score = 81.3 bits (199), Expect = 5e-15 Identities = 72/307 (23%), Positives = 120/307 (39%), Gaps = 16/307 (5%) Query: 649 RLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTK---LQVSKS 705 RL+I ++ G++ C A W +N + +W + + S + V QP K +++ Sbjct: 63 RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNV-QPTEKEFTVRLETE 121 Query: 706 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYA 765 KR + E P++ C ++Q + +FAV W + LI N+ + Sbjct: 122 KRLHMVGE--PVEFRCIPEAQNVPDRYFAVSWAFNS------SLIATMGPNAVPVLNSEF 173 Query: 766 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 825 R +L + S +F L + DSG Y C V E + + + Sbjct: 174 AHREARGQLNVAKE-SDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232 Query: 826 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNHPER 884 + V +S + + A +LE ++ C V + V W V + N R Sbjct: 233 IPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNR--R 290 Query: 885 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 944 + L RD T G + + G + +E P + L I N +D G Y CHV EW+ Sbjct: 291 SDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 350 Query: 945 PSPSGMW 951 G W Sbjct: 351 RVVDGEW 357 Score = 57.4 bits (137), Expect = 8e-08 Identities = 59/262 (22%), Positives = 96/262 (36%), Gaps = 44/262 (16%) Query: 887 VARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPS 946 V LSRD H G + A G + L+ +RL I ++ D G + C EW+ + Sbjct: 28 VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87 Query: 947 PSGMWY----KRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQ 1002 P G WY KR+E T + +++++T V E F+ C +++ Sbjct: 88 PDGSWYAMTRKRSEGAVVNVQPT--EKEFTVRLETEKRLHMVGEPVEFR--CIPEAQNVP 143 Query: 1003 DSRFAVAW--YSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDA 1060 D FAV+W S G + P L + RE Sbjct: 144 DRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREA------------------------- 178 Query: 1061 VFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE 1120 G+L + S ++ L + +D+G Y+C V E + E+ + Sbjct: 179 ---------RGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKH 229 Query: 1121 SAPIGIRVLDTSPTLQSIICSN 1142 I I VL ++ + SN Sbjct: 230 PKNIPIIVLPLESSISVEVASN 251 Score = 35.8 bits (81), Expect = 0.25 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%) Query: 34 EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 92 EG + C+V P + + W + + ++ + + P + Y +R G Sbjct: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316 Query: 93 IFIERVQGNSTLLHITDLQARDAGEYECH 121 + +E+VQ NS L I + + D G+YECH Sbjct: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345 >gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens] Length = 1021 Score = 620 bits (1598), Expect = e-177 Identities = 368/980 (37%), Positives = 549/980 (56%), Gaps = 54/980 (5%) Query: 4 FFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPS 63 FF +L+ L++ QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP+ Sbjct: 10 FFLLLTKLSI-----GQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64 Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123 +P +EVQI+ST D++F YA+YTQRVR G +++ERVQGNS LLHI+ LQ +DAGEYECHTP Sbjct: 65 NPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTP 124 Query: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183 +TD++Y+GSYSAK NL+VIPD+L T QTL + E +PL LTCE + T QH+HLSV W Sbjct: 125 NTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184 Query: 184 --LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQ 241 + G + E+ISLS+DF+L Y +R + +V+L+KLG TTFRL+I LQ SDQ Sbjct: 185 YLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQ 244 Query: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301 G+ +CEA EWIQDPD +W +T+K+++ + +QP K+F V + T L G+P+E Sbjct: 245 GQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELV 303 Query: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361 C++ + D W FN + IA + V L +++ R ++G+L+V+K F L Sbjct: 304 CLVVSSG-RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSL 362 Query: 362 KIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQL 421 KI+ L ED G Y C V E KT TG + + K+ P H Sbjct: 363 KIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQS------------------PDSHVH 404 Query: 422 LSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR-QNRRSNI 480 L + S+ + + V+ EGE L F C AG + SV W + R Q + + Sbjct: 405 LRK-PAARSVVMSTKNKQQVVWEGETLAFLCK---AGGAESPLSVSWWHIPRDQTQPEFV 460 Query: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR-- 538 + +DG VQ G+SY S G ++E++ +F L I + D G YEC V+E R Sbjct: 461 AGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQ 520 Query: 539 AVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHY-PAWVP 597 A D W +++ +LE V+ +SR P V +++FDL C+++ Y VP Sbjct: 521 ARDLSW------TQKISVTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVP 574 Query: 598 VSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASD 657 ++VTW+FQP + FH L+ T +G ++WG+ S F+ +T + ++S +L + A++ Sbjct: 575 LTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKV--SQSLFRSQLLVHDATE 632 Query: 658 TEAGKYQCVAELWRKN--YNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENK 715 E G YQC E++ +N YNN R A S+ L I V P +KL+V+ + L N Sbjct: 633 EETGVYQCEVEVYDRNSLYNNRPPR-ASAISHPLRIAVTLPESKLKVNSRSQVQELSINS 691 Query: 716 PIQLNCSVKSQTSQNSHFAVLWYVHKPS-DADGKLILKTTHNSAFEYGTYAEEEGLRARL 774 + CS+ S+++ N A++WY S +A IL+ + + G + + Sbjct: 692 NTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKF 751 Query: 775 QFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPD 834 E+ VS LF L + E SD G Y+C VEEWLLS N W+KL E+ SG TE+ +K Sbjct: 752 HTEK-VSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTG 810 Query: 835 SRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDA 894 S++R+S+ +V E R+V + C + + S + V W+ W + + + L D Sbjct: 811 SKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWY-WNRENSGSKLLVHLQHDG 869 Query: 895 TFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEW-LPSPSGMWYK 953 YGE+ L+ LH S + L + V ++D+G Y C V EW L W Sbjct: 870 LLEYGEE----GLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWIN 925 Query: 954 RAEDTAGQTALTVMRPDASL 973 +A D + + LTV+ + +L Sbjct: 926 QASDESQRMVLTVLPSEPTL 945 Score = 258 bits (658), Expect = 3e-68 Identities = 276/1090 (25%), Positives = 448/1090 (41%), Gaps = 127/1090 (11%) Query: 132 SYSAKMNLVVIPDSL---QTTAMPQTLHRVEQDPLELTCEVASE---TIQHSHLSVAWLR 185 SY A L++ S+ + T L R E P+ + C V + QH SV Sbjct: 5 SYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64 Query: 186 QKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 245 E V++IS ++D S + Y QR G+V ++++ + L I LQ D GE+ Sbjct: 65 NPTQE--VQIIS-TKDAAF-SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120 Query: 246 CEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILE 305 C + GS+ A T + V P T+ +T + GEP+ C Sbjct: 121 CHTPNTDEKYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEAS 171 Query: 306 AQNVPDRYFAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSV 358 + +V+W ++ I ++ + + V + R A +++ K + Sbjct: 172 KATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTT 231 Query: 359 FVLKIYHLRQEDSGKYNCRVTE--REKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVP 416 F L I L+ D G+ C TE ++ T FI K K+ + + P ++ V + Sbjct: 232 FRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNIT 289 Query: 417 QHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNR 476 S+ EG+ L C V ++GR + IW Sbjct: 290 AD---------------------SLFAEGKPLELVCLVVSSGRDP-QLQGIWFF-----N 322 Query: 477 RSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEW 536 + I +D G + + Y ER+S G +Q+ ++ P +FSL IF+ EDEG Y C V E Sbjct: 323 GTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEV 382 Query: 537 VRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPG----VTYSDSFDLQCIIKPHY 592 ++ G WQ++ +R +P S L A + + T V ++ C Sbjct: 383 MKTRTGSWQVL--QRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGG-- 438 Query: 593 PAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSS--SFRTRTAIEKAESSNNVRL 650 A P+SV+W P + + +DG VQ G S+ T +EK + + +L Sbjct: 439 -AESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWAT-FQL 496 Query: 651 SISRASDTEAGKYQC-VAELWRKNYNN-TWTRLAERTSNLLEIRVLQPVTKLQVSKSKRT 708 I+ + T++G Y+C V+E R + +WT+ T LE + LQVS R Sbjct: 497 EITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLE-------SSLQVSLMSRQ 549 Query: 709 LTLVENKPIQLNCSVKSQTSQ-NSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEE 767 ++ L+C V++ S V W S +++ THN E+G + Sbjct: 550 PQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFL-- 607 Query: 768 EGLRARLQFERHVSGGLF--SLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYK-LAEEVSG 824 +R Q + VS LF L V A ++G Y C VE + + Y A +S Sbjct: 608 ----SRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISH 663 Query: 825 RTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPER 884 + V P+S+L+++ + +EC +L+R++ QL + W+ + P Sbjct: 664 PLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWY-FSPVSTNA 722 Query: 885 ETVARLSRDAT--FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEE 942 + L D T G++ K + H E S +++L I NV D G Y C VEE Sbjct: 723 SWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEE 782 Query: 943 WLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQ 1002 WL S +G W+K E +G T L + + ++V V V+E + CS+ S S Sbjct: 783 WLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSS 842 Query: 1003 DSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAV- 1061 + ++V WY R +G K L+ + D + Sbjct: 843 ATLYSVMWYWNRENSGSK-------------------------------LLVHLQHDGLL 871 Query: 1062 -FGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEW-LPSPQKEWYRLTEE 1119 +G EG L R S + L + Q +D G Y C V EW L +W + Sbjct: 872 EYGEEG--LRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASD 929 Query: 1120 ESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSD 1179 ES + + VL + PTL S ICS+ L YF+F PF + +L+I++L + +K+R S Sbjct: 930 ESQRMVLTVLPSEPTLPSRICSSAPLLYFLFICPFVLLLLLLISLLCLYWKARKLSTLRS 989 Query: 1180 GKNGVPLLWI 1189 LW+ Sbjct: 990 NTRKEKALWV 999 >gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] Length = 613 Score = 281 bits (718), Expect = 3e-75 Identities = 188/586 (32%), Positives = 287/586 (48%), Gaps = 65/586 (11%) Query: 8 LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPER 67 L L +LG+ R+V V EGPLYR G+ ++I CNV+GY+GP++QNF+W +Y P +P+ Sbjct: 15 LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74 Query: 68 EVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDK 127 + IVST D+ F YA++ RV G++ ++R+QG++ +L I LQA+DAG YECHTPSTD Sbjct: 75 ALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDT 134 Query: 128 QYFGSYSAKMNLVVIPDSLQTTAMP--------------QTLHRVEQDPLELTCEVASET 173 +Y GSYS K+ L V+PD LQ +A P T+H E L L C + T Sbjct: 135 RYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVH--EGQELALGCLARTST 192 Query: 174 IQHSHLSVAWLRQKVGEKPV------EVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRT 227 +H+HL+V++ R V E PV EV+ + D + + + YA+R + GE+RL K G Sbjct: 193 QKHTHLAVSFGR-SVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251 Query: 228 TFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLET 287 +R+ + Q D G ++C AAEWIQDPDGSW + KR+ A V+VQ + V + Sbjct: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311 Query: 288 EKRLHTVGEPVEFRCILEAQNVP-DRYFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREA 345 +R GEP+E C + P R+ A S + + GP V L++E Sbjct: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371 Query: 346 RG----QLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIP 401 G + + K + + L++ R D+G Y C + + S R + +P Sbjct: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431 Query: 402 IIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVAS--NASVILEGEDLRFSCSVRTAGR 459 + V E + +E + + GE C++ G Sbjct: 432 VHV----------------------REEGVVLEAVAWLAGGTVYRGETASLLCNISVRGG 469 Query: 460 PQG-RFSVIWQLVDRQNRRSN------IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPN 512 P G R + W + ++ + + + +DG + G R G V +E V P Sbjct: 470 PPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VRPGGGPVSVELVGPR 525 Query: 513 SFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISI 558 S L + + EDEG Y C + WV+ D W G R S P+++ Sbjct: 526 SHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSAR-SGPVTV 570 Score = 95.1 bits (235), Expect = 4e-19 Identities = 109/499 (21%), Positives = 188/499 (37%), Gaps = 58/499 (11%) Query: 648 VRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKL------- 700 V L I+R +AG Y+C + +T TR S +E+RVL V ++ Sbjct: 110 VVLKIARLQAQDAGIYEC-------HTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGP 162 Query: 701 ---QVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTT--- 754 Q S +T+ E + + L C ++ T +++H AV + P G+ L+ Sbjct: 163 RGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGI 222 Query: 755 -HNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 813 + A E G E L+ + + + + V A+ D+G+Y+C EW+ P+ Sbjct: 223 RSDLAVEAGAPYAERLAAGELRLGKEGTDR-YRMVVGGAQAGDAGTYHCTAAEWIQDPDG 281 Query: 814 AWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSITSQL 870 +W ++AE+ + V V+ S+L ++ G + ++L C V L + Sbjct: 282 SWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAY 341 Query: 871 MVEWFVWKPNHP-ERETVARLSRDATFHYGEQAAKNNLKGR-LHLESPSPGVYRLFIQNV 928 V W + P VA+L + G +GR + +E + YRL ++ Sbjct: 342 SVGWEMAPAGAPGPGRLVAQLDTEGVGSLGP-----GYEGRHIAMEKVASRTYRLRLEAA 396 Query: 929 AVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKA 988 D+GTY C + ++ + A + + V L+ + TV Sbjct: 397 RPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGE 456 Query: 989 AFQLDCSIVSRSSQDS-RFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDP 1047 L C+I R R A +W+ R + G S P Sbjct: 457 TASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPA---------------------- 494 Query: 1048 TERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLP 1107 + VG D V P G + + + P +RL + P+D G Y C W+ Sbjct: 495 ---QLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQ 551 Query: 1108 SPQKEWYRLTEEESAPIGI 1126 WY+ S P+ + Sbjct: 552 HADYSWYQAGSARSGPVTV 570 Score = 81.6 bits (200), Expect = 4e-15 Identities = 89/441 (20%), Positives = 166/441 (37%), Gaps = 50/441 (11%) Query: 712 VENKPIQLNCSV---KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEE 768 V + ++C+V + QN W++++P D L + +T ++ F Y + + Sbjct: 40 VAGTAVSISCNVTGYEGPAQQNFE----WFLYRPEAPDTALGIVSTKDTQFSYAVF-KSR 94 Query: 769 GLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE--EWLLSPNYAWYKLAEEVSGRT 826 + +Q +R + G L + R + D+G Y CH + +Y+ + Sbjct: 95 VVAGEVQVQR-LQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVL 153 Query: 827 EVTVKQPDSRLRLSQAQG-NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP--- 882 +V+ P R R + ++V E +++ L C+ T + L V + P P Sbjct: 154 QVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGR 213 Query: 883 -ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVE 941 + V + D G A+ G L L YR+ + D+GTY C Sbjct: 214 STLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAA 273 Query: 942 EWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI---VS 998 EW+ P G W + AE A + V + L V + +L C++ + Sbjct: 274 EWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333 Query: 999 RSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGP 1058 + + + ++V W A G PG + + E + S+GP Sbjct: 334 PAGRHAAYSVGWEMAPAGAPG----PGRLVAQLDTE-----------------GVGSLGP 372 Query: 1059 DAVFGPEGSPWEGR-LRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLT 1117 +EGR + ++++ YRL + A P D G Y C + ++ Sbjct: 373 G---------YEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA 423 Query: 1118 EEESAPIGIRVLDTSPTLQSI 1138 S P+ + V + L+++ Sbjct: 424 SARSRPLPVHVREEGVVLEAV 444 Score = 80.5 bits (197), Expect = 9e-15 Identities = 97/485 (20%), Positives = 193/485 (39%), Gaps = 42/485 (8%) Query: 502 GGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV----TEWVRAVDGEWQIVGERRASTPIS 557 G VQ++++Q ++ L I + +D G YECH T ++ + G+ ++ R + Sbjct: 98 GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVEL---RVLPDVLQ 154 Query: 558 ITALEMG-FAVTAISRTPGVTYSDSFDLQ--CIIKPHYPAWVPVSVTWRFQ----PVGTV 610 ++A G A + P +T + +L C+ + ++V++ PVG Sbjct: 155 VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214 Query: 611 EFHDLVTFTRD----GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 666 ++V D G + +R ++ R E ++ R+ + A +AG Y C Sbjct: 215 TLQEVVGIRSDLAVEAGAPYAERLAAGELRLG---KEGTDRYRMVVGGAQAGDAGTYHCT 271 Query: 667 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKS- 725 A W ++ + +W ++AE+ + L + V ++L V+ + +P++L C+V Sbjct: 272 AAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGA 331 Query: 726 --QTSQNSHFAVLWYVHKPSDA--DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVS 781 +++ ++V W + P+ A G+L+ + G G R V+ Sbjct: 332 LPPAGRHAAYSVGWEM-APAGAPGPGRLVAQLDTEGVGSLG-----PGYEGRHIAMEKVA 385 Query: 782 GGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQ 841 + L ++ A D+G+Y C + ++ + A S V V++ L Sbjct: 386 SRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVA 445 Query: 842 AQGNLSVLETRQVQLECVVLNRTSITS-QLMVEWFVWKPNHPE-----RETVARLSRDAT 895 +V L C + R +L W+V +P E + V + +D Sbjct: 446 WLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGV 505 Query: 896 FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRA 955 G + G + +E P +RL + ++ +D G Y C W+ WY+ Sbjct: 506 AELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAG 561 Query: 956 EDTAG 960 +G Sbjct: 562 SARSG 566 >gi|41152506 prostaglandin F2 receptor negative regulator [Homo sapiens] Length = 879 Score = 245 bits (625), Expect = 2e-64 Identities = 218/858 (25%), Positives = 365/858 (42%), Gaps = 75/858 (8%) Query: 6 PVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65 P+L L L + R V V L R G+ + I CNVS Y GPSEQNF WS S Sbjct: 8 PLLLALLSLALCRG-RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLG 64 Query: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPST 125 V++ ST + FP +Y +R++ G+I + R ++ LHI ++Q D G Y+C TPST Sbjct: 65 SSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPST 124 Query: 126 DKQYFGSYSAKMNLVVIPDSLQ---TTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVA 182 D G+Y + + V+ DSL + P +L E +P EL C AS + H+HL++ Sbjct: 125 DATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALL 184 Query: 183 WLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQG 242 W + G V++L+ + H Y QR G+VRLD +G +RL++ +DQG Sbjct: 185 WEVHR-GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQG 243 Query: 243 EFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTV-GEPVEFR 301 + C +EWI + G+W + K E A V +QP+ +R K + G+ ++ Sbjct: 244 SYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLT 298 Query: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361 C + D V+W+F+ +T+ + V + + + ++ + L Sbjct: 299 CNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHL 358 Query: 362 KIYHLRQEDSGKYNCRVT--EREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHH 419 + + +E+SG Y C V+ + + + P + + W Sbjct: 359 LVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGV-------TW-------- 403 Query: 420 QLLSQGHLESSISVEVASNASVILEGEDLRFSCSV--RTAGRPQGRFSVIWQLVDRQNRR 477 LE V + ++ + +C V +G RF+V W R NRR Sbjct: 404 -------LEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYY--RMNRR 454 Query: 478 SN-------IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYE 530 S+ + +D D T++ G +R+ G + ++F+ I + +ED G Y Sbjct: 455 SDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYY 514 Query: 531 CHVTEWVRAVDGEWQIVGERRASTPISI-TALEMG-FAVTAISRTPGVTYSDSFDLQC-- 586 C V+ W + + W + + S P++I ALE V A P ++F++ C Sbjct: 515 CVVSAWTKQRNNSW-VKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKV 573 Query: 587 ----IIKPHYPAWVPVSVTWRFQPVGTV----EFHDLVTFTRDGGVQWGDRSSSFRTRTA 638 I P Y + +PVG + E +++ +D V+ + + + R Sbjct: 574 SSKNIKSPRYSVLIMAE-----KPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGV 628 Query: 639 IEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVT 698 + + + R + + ++AG Y+C+ W + W A SN +EI Sbjct: 629 VLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGP 688 Query: 699 KLQVSKSKRTLTLVENKPIQLNCSVKSQTS----QNSHFAVLWY-VHKPSDADGKLILKT 753 S T +++ I+L C + + + + F V W+ VH ++L + Sbjct: 689 IFNASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSS 748 Query: 754 THNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 813 ++ L ER VS F L V +E D G+YYC V W+ SP Sbjct: 749 LDRKGI---VTTSRRDWKSDLSLER-VSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTG 804 Query: 814 AWYKLAEEVSGRTEVTVK 831 +W K AE S +TVK Sbjct: 805 SWQKEAEIHSKPVFITVK 822 Score = 176 bits (446), Expect = 1e-43 Identities = 185/867 (21%), Positives = 322/867 (37%), Gaps = 90/867 (10%) Query: 283 VRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 339 VR+ T + VG + C + + P W+F+S S + V Sbjct: 24 VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82 Query: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399 + R RG++ + + ++ L I +++ D G Y C + TV G + D Sbjct: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDT------- 135 Query: 400 IPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGR 459 + V L D+ L S + S + EGE C+ +A Sbjct: 136 --VQVKVLADS----------------LHVGPSARPPPSLS-LREGEPFELRCTAASASP 176 Query: 460 PQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIF 519 +++W+ V R R +++ L +G PG Y +R G V+++ V +++ L + Sbjct: 177 LHTHLALLWE-VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVS 235 Query: 520 NSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYS 579 + D+G Y C V+EW+ A G WQ + E+ + ++ ++ A+ + V Sbjct: 236 RALSADQGSYRCIVSEWI-AEQGNWQEIQEK--AVEVATVVIQPSVLRAAVPKNVSVAEG 292 Query: 580 DSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAI 639 DL C I V VTW F + R DR S + + Sbjct: 293 KELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLAR------LDRDSLVHSSPHV 346 Query: 640 EKAE-SSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRV--LQP 696 + + + L + S +G Y C LW +N +W ++AE S+ + V L+P Sbjct: 347 ALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEP 406 Query: 697 VTKLQVSKSKRTLTLVENKPIQLNCSVKSQTS--QNSHFAVLWY--VHKPSD--ADGKLI 750 ++ ++ SK + + P +L C V S N F V WY +++ SD +L+ Sbjct: 407 DYQVYLNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELL 464 Query: 751 LKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLS 810 + +YG +++ F + + F+ +QR D G+YYC V W Sbjct: 465 AVMDGDWTLKYGERSKQRAQDGDFIFSKEHT-DTFNFRIQRTTEEDRGNYYCVVSAWTKQ 523 Query: 811 PNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQL 870 N +W K + S + DS L + Q ++ C V ++ + + Sbjct: 524 RNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRY 583 Query: 871 MVEWFVWKP-----NHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFI 925 V KP + E + + L +D+ + + G + LE +R + Sbjct: 584 SVLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDG-VVLEKVQEDEFRYRM 642 Query: 926 QNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVS 985 V D+G Y C V W P +W + A + + +V Sbjct: 643 YQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVI 702 Query: 986 EKAAFQLDCSIVSRSS----QDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDD 1041 +L C I + D F V+W+++ S GL++ Sbjct: 703 RGDLIKLFCIITVEGAALDPDDMAFDVSWFAVH--------SFGLDKAP----------- 743 Query: 1042 DDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCH 1101 L S+ + W+ L +R+S + + L V + QD GNY C Sbjct: 744 ---------VLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCS 794 Query: 1102 VEEWLPSPQKEWYRLTEEESAPIGIRV 1128 V W+ SP W + E S P+ I V Sbjct: 795 VTPWVKSPTGSWQKEAEIHSKPVFITV 821 Score = 151 bits (381), Expect = 4e-36 Identities = 192/841 (22%), Positives = 316/841 (37%), Gaps = 77/841 (9%) Query: 154 TLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR 213 TL RV L + C V S+ S + W +G VE+ S + + Y +R Sbjct: 30 TLVRVVGTELVIPCNV-SDYDGPSEQNFDWSFSSLGSSFVELASTWE--VGFPAQLYQER 86 Query: 214 QSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVN 273 GE+ L + L I ++QPSDQG + C G++ + + ++ Sbjct: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146 Query: 274 VQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSW------AFNSSLIAT 327 V P+ + E GEP E RC + + + A+ W A S L T Sbjct: 147 VGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALT 200 Query: 328 MGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTG 387 P L E R G +++ + L + D G Y C V+E G Sbjct: 201 HEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE-QG 257 Query: 388 EFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGED 447 + + + K + +++ P S + V N SV EG++ Sbjct: 258 NWQEIQEKAVEVATVVIQP----------------------SVLRAAVPKNVSVA-EGKE 294 Query: 448 LRFSCSVRTAGRPQGRFSVIW---QLVDRQNRRSNIMW-LDRDGTVQPGSSYWERSSFGG 503 L +C++ T R V W ++ D S ++ LDRD V S Sbjct: 295 LDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPH 345 Query: 504 VQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTP-ISITALE 562 V + V S+ L + + KE+ G Y CHV+ W + W V E +S + +T LE Sbjct: 346 VALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLE 405 Query: 563 MGFAVTA-ISRTPGVTYSDSFDLQCII--KPHYPAWVPVSVTWRFQ----PVGTVEFHDL 615 + V S+ PG D +L C + A V +V+W ++ V L Sbjct: 406 PDYQVYLNASKVPGFA-DDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELL 464 Query: 616 VTFTRDGGVQWGDRSSS-FRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNY 674 D +++G+RS + I E ++ I R ++ + G Y CV W K Sbjct: 465 AVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQR 524 Query: 675 NNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFA 734 NN+W + + S + I + L V + ++ C V S+ ++ ++ Sbjct: 525 NNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYS 584 Query: 735 VLWYVHKP-----SDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTV 789 VL KP S + K I+ +S + + + + + V F + Sbjct: 585 VLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVL--EKVQEDEFRYRM 642 Query: 790 QRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVL 849 + +VSD+G Y C V W W + A +S E+ + S SV+ Sbjct: 643 YQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVI 702 Query: 850 ETRQVQLECVV-LNRTSITSQLM---VEWFVWKPNHPERETVARLSRDATFHYGEQAAKN 905 ++L C++ + ++ M V WF ++ V S D ++ Sbjct: 703 RGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIV--TTSRR 760 Query: 906 NLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALT 965 + K L LE S + L + QD G Y C V W+ SP+G W K AE + +T Sbjct: 761 DWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFIT 820 Query: 966 V 966 V Sbjct: 821 V 821 Score = 135 bits (339), Expect = 3e-31 Identities = 138/675 (20%), Positives = 247/675 (36%), Gaps = 79/675 (11%) Query: 491 PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGER 550 P Y ER G + + + ++ L I N + D+G Y+C V G ++ Sbjct: 79 PAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE----- 133 Query: 551 RASTPISITALEMGFAVTAISRTP---GVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPV 607 + + L V +R P + + F+L+C P +++ W Sbjct: 134 ---DTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVHR- 189 Query: 608 GTVEFHDLVTFTRDG----GVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKY 663 G ++ T +G G+ + R S R S+ RLS+SRA + G Y Sbjct: 190 GPAR-RSVLALTHEGRFHPGLGYEQRYHSGDVRL---DTVGSDAYRLSVSRALSADQGSY 245 Query: 664 QCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSV 723 +C+ W N W + E+ + + + V + V K+ +++ E K + L C++ Sbjct: 246 RCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPKN---VSVAEGKELDLTCNI 301 Query: 724 KSQTSQNSHFAVLWYVHKPSDAD---GKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780 + + + V W + D+ +++ + +S + HV Sbjct: 302 TTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALS----------HV 351 Query: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVK--QPDSRLR 838 + L V+ +SG YYCHV W N +W+K+AE VS V V +PD ++ Sbjct: 352 DARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVY 411 Query: 839 LSQAQGNLSVLETRQVQLECVVLNRTS--ITSQLMVEWFVWKPNHPER----ETVARLSR 892 L+ ++ + +L C V++ S + V W+ + E +A + Sbjct: 412 LNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDG 469 Query: 893 DATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWY 952 D T YGE++ + G + IQ +D G Y C V W + W Sbjct: 470 DWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV 529 Query: 953 KRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYS 1012 K + + + D+ L V P + F++ C + S++ + R++V + Sbjct: 530 KSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMA 589 Query: 1013 LRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGR 1072 E+ D P E ++S+ D+V E W Sbjct: 590 -------------------------EKPVGDLSSPNETKYIISLDQDSVVKLEN--WTDA 622 Query: 1073 LR-----FQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIR 1127 R +++ +R + Q D G Y C V W P W S PI I Sbjct: 623 SRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEID 682 Query: 1128 VLDTSPTLQSIICSN 1142 + P + + S+ Sbjct: 683 FQTSGPIFNASVHSD 697 Score = 130 bits (326), Expect = 1e-29 Identities = 147/676 (21%), Positives = 250/676 (36%), Gaps = 70/676 (10%) Query: 57 WSIYLPSSPEREVQIVSTMDSSF-PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDA 115 W ++ P R + T + F P Y QR G + ++ V ++ L ++ + D Sbjct: 185 WEVH--RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQ 242 Query: 116 GEYECHTPST-----DKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVA 170 G Y C + Q + ++ VVI S+ A+P+ + E L+LTC + Sbjct: 243 GSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNIT 302 Query: 171 SETIQHSHLSVAWLRQKVGEKPVE----VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGR 226 ++ V W ++ + + + L RD ++HSS A L + Sbjct: 303 TDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVA---------LSHVDA 353 Query: 227 TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLE 286 ++ L + + + G +YC + W + SW+ + S A V V + ++ V L Sbjct: 354 RSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLN 413 Query: 287 TEKRLHTVGEPVEFRC--ILEAQNVPDRYFAVSWAFN----------SSLIATMGPNAVP 334 K +P E C + + F VSW + S L+A M + Sbjct: 414 ASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTL 473 Query: 335 VLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394 R G +KE F +I +ED G Y C V+ K ++ Sbjct: 474 KYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV---- 529 Query: 395 KRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSV 454 K+ + P+ W ++ +S + V+ G +C V Sbjct: 530 ---KSKDVFSKPVNIFWALE-------------DSVLVVKARQPKPFFAAGNTFEMTCKV 573 Query: 455 RTAGRPQGRFSVIWQL------VDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQ 508 + R+SV+ + N I+ LD+D V+ ++ + S GV +E+ Sbjct: 574 SSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEK 632 Query: 509 VQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMG--FA 566 VQ + F ++ ++ D G Y C VT W W+ S PI I G F Sbjct: 633 VQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATS-LSNPIEIDFQTSGPIFN 691 Query: 567 VTAISRTPGVTYSDSFDLQCIIKPHYPAWVP----VSVTW-RFQPVGTVEFHDLVTFTRD 621 + S TP V D L CII A P V+W G + L++ Sbjct: 692 ASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDR 751 Query: 622 GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRL 681 G+ R +++ ++E+ S L + + D + G Y C W K+ +W + Sbjct: 752 KGIVTTSRRD-WKSDLSLERV-SVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKE 809 Query: 682 AERTSNLLEIRVLQPV 697 AE S + I V V Sbjct: 810 AEIHSKPVFITVKMDV 825 >gi|169215606 PREDICTED: similar to immunoglobulin superfamily, member 3 [Homo sapiens] Length = 195 Score = 240 bits (612), Expect = 7e-63 Identities = 115/117 (98%), Positives = 116/117 (99%) Query: 16 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 75 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM Sbjct: 79 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 138 Query: 76 DSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGS 132 DSSFPYAIYTQRVRGGKIFIERVQGN TLLHITDLQARDAGEYECHTPST+KQYFGS Sbjct: 139 DSSFPYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 195 Score = 38.1 bits (87), Expect = 0.051 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 701 QVSKSKRTLTLVENKPIQLNCSVKS-QTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAF 759 QV+ + L E I + C+V Q +F W ++ PS + ++ + +T +S+F Sbjct: 85 QVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQ--WSIYLPSSPEREVQIVSTMDSSF 142 Query: 760 EYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCH 803 Y Y + +R F V G L + + D+G Y CH Sbjct: 143 PYAIYTQR--VRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 184 Score = 37.4 bits (85), Expect = 0.087 Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 13/118 (11%) Query: 822 VSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNH 881 VS + +VTV++ G L E + + C V + Q +W ++ P+ Sbjct: 80 VSAQRQVTVQE-----------GPLYRTEGSHITIWCNVSGYQGPSEQNF-QWSIYLPSS 127 Query: 882 PERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCH 939 PERE + D++F Y + G++ +E L I ++ +D+G Y CH Sbjct: 128 PEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNPTLLHITDLQARDAGEYECH 184 Score = 32.7 bits (73), Expect = 2.2 Identities = 16/42 (38%), Positives = 24/42 (57%) Query: 491 PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 532 P + Y +R G + +E+VQ N L I + + D G+YECH Sbjct: 143 PYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 184 >gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens] Length = 155 Score = 240 bits (612), Expect = 7e-63 Identities = 115/117 (98%), Positives = 116/117 (99%) Query: 16 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 75 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM Sbjct: 39 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 98 Query: 76 DSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGS 132 DSSFPYAIYTQRVRGGKIFIERVQGN TLLHITDLQARDAGEYECHTPST+KQYFGS Sbjct: 99 DSSFPYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 155 Score = 38.1 bits (87), Expect = 0.051 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 701 QVSKSKRTLTLVENKPIQLNCSVKS-QTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAF 759 QV+ + L E I + C+V Q +F W ++ PS + ++ + +T +S+F Sbjct: 45 QVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQ--WSIYLPSSPEREVQIVSTMDSSF 102 Query: 760 EYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCH 803 Y Y + +R F V G L + + D+G Y CH Sbjct: 103 PYAIYTQR--VRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 144 Score = 37.4 bits (85), Expect = 0.087 Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 13/118 (11%) Query: 822 VSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNH 881 VS + +VTV++ G L E + + C V + Q +W ++ P+ Sbjct: 40 VSAQRQVTVQE-----------GPLYRTEGSHITIWCNVSGYQGPSEQNF-QWSIYLPSS 87 Query: 882 PERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCH 939 PERE + D++F Y + G++ +E L I ++ +D+G Y CH Sbjct: 88 PEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNPTLLHITDLQARDAGEYECH 144 Score = 33.1 bits (74), Expect = 1.6 Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 12/126 (9%) Query: 418 HHQLLSQGH----LESSISVEVASNASVI-------LEGEDLRFSCSVRTAGRPQGRFSV 466 HH+ L Q ++++ SV A + EG + C+V P + + Sbjct: 20 HHEFLRQSDGATLVQNNHSVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQ-NF 78 Query: 467 IWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDE 526 W + + + + + P + Y +R G + +E+VQ N L I + + D Sbjct: 79 QWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDA 138 Query: 527 GQYECH 532 G+YECH Sbjct: 139 GEYECH 144 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 61.2 bits (147), Expect = 6e-09 Identities = 174/847 (20%), Positives = 289/847 (34%), Gaps = 193/847 (22%) Query: 81 YAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLV 140 +A T RGG + R Q + +LL + + D+GEY CH T S + Sbjct: 2180 HAQVTWHKRGGSL-PARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEAS 2238 Query: 141 VIPDSLQTTAMPQTLHRV-EQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLS 199 VIP + + + V E L+L+C VA + +H V W ++ Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQ----AHAQVTWYKR------------- 2281 Query: 200 RDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSW 259 S A+ Q G RL IF P+D G++ C A+ ++ + Sbjct: 2282 ------GGSLPARHQVRGS-----------RLYIFQASPADAGQYVCRASNGME----AS 2320 Query: 260 YAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWA 319 +T ++GA + P +R+E G+ ++ C++ Q+ + V+W Sbjct: 2321 ITVTVTGTQGANL-AYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS----HAQVTW- 2374 Query: 320 FNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVT 379 H+ G L V ++ +L++Y DSG+Y CRV Sbjct: 2375 ----------------------HKRG-GSLPVRHQTHG-SLLRLYQASPADSGEYVCRVL 2410 Query: 380 EREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNA 439 +PL + +V + + + G + +V + S++ Sbjct: 2411 GSS----------------------VPLEASVLVTIEPAGSVPALG---VTPTVRIESSS 2445 Query: 440 SVILEGEDLRFSCSVRTAGRPQ-------GRFSVIWQLVDRQNRRSNIMWLDRDGTV--Q 490 S + EG+ L +C V Q G Q+ + R + D V Sbjct: 2446 SQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRV 2505 Query: 491 PGSSYWERSSFGGVQMEQVQPNSFSLGI-FNSRKEDEG---------QYEC-------HV 533 GSS + +S V ++Q S S G+ + R E C H Sbjct: 2506 VGSSGTQEASV-LVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHT 2564 Query: 534 TEWVR---AVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSF-DLQCIIK 589 W + ++ QIVG R +T + G V +S G + +Q Sbjct: 2565 ITWYKRGGSLPSRHQIVGSRLRIP--QVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622 Query: 590 PHYPAWVPVSVTWRFQPV----GTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESS 645 H P+ P P T++ + +V + W R S +R + Sbjct: 2623 SHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSR------HQT 2676 Query: 646 NNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEI-----RVLQPVTKL 700 + L + + S ++G+Y C A NN L S ++ + P + + Sbjct: 2677 HGSHLRLHQMSVADSGEYVCRA-------NNNIDAL--EASIVISVSPSAGSPSAPGSSM 2727 Query: 701 QVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFE 760 + + + E + + LNC V Q +H V W H Sbjct: 2728 PIRIESSSSHVAEGETLDLNCVVPGQ----AHAQVTW-----------------HKRGGS 2766 Query: 761 YGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAE 820 ++ + G R RL HVS +DSG Y C V P A + Sbjct: 2767 LPSHHQTRGSRLRL---HHVS------------PADSGEYVCRV-MGSSGPLEASVLVTI 2810 Query: 821 EVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPN 880 E SG + V V P + + V E + + L+CVV + + V W N Sbjct: 2811 EASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ----AHAQVTWHKRGGN 2866 Query: 881 HPERETV 887 P R V Sbjct: 2867 LPARHQV 2873 Score = 59.3 bits (142), Expect = 2e-08 Identities = 187/991 (18%), Positives = 320/991 (32%), Gaps = 258/991 (26%) Query: 80 PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNL 139 P AI T RGG + R Q + + L + + D+GEY C + S ++ Sbjct: 2657 PQAIITWYKRGGSL-PSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715 Query: 140 VVIPDSLQTTAMP-----QTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVE 194 S ++MP + H E + L+L C V + +H V W ++ G P Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQ----AHAQVTW-HKRGGSLP-- 2768 Query: 195 VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQD 254 + Q+ G RL + H+ P+D GE+ C Sbjct: 2769 ----------------SHHQTRGS-----------RLRLHHVSPADSGEYVCRVMG-SSG 2800 Query: 255 PDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYF 314 P + +T + S + V+V +R+E G+ ++ +C++ Q + Sbjct: 2801 PLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ----AHA 2856 Query: 315 AVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKY 374 V+W + A + G L L++ + DSG+Y Sbjct: 2857 QVTWHKRGGNLP--------------ARHQVHGPL-----------LRLNQVSPADSGEY 2891 Query: 375 NCRVTEREKTVTGEF---IDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSI 431 +C+VT T+ I+ S P P + P+ ++E+S Sbjct: 2892 SCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPI------------------YIEAS- 2932 Query: 432 SVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIW-----QLVDRQNRRSNIMWLDRD 486 +S + EG+ L +C V Q V W L R + + L Sbjct: 2933 -------SSHVTEGQTLDLNCVVPGQAHAQ----VTWYKRGGSLPARHQTHGSQLRLHLV 2981 Query: 487 GTVQPGSSYWERSSFGGVQMEQ-----VQPNSFSLGIFNS------------RKEDEGQY 529 G +S G + E V P+ S S ++ + + Sbjct: 2982 SPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASF 3041 Query: 530 ECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGV--TY----SDSFD 583 +C + + + EW+ R ++ G +T + P TY S+++ Sbjct: 3042 KCLIHDGAAPISLEWKT---RNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYG 3098 Query: 584 L-QCIIK------------PHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRS 630 + Q ++ P P WV V + V E +TR Sbjct: 3099 VAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTP----- 3153 Query: 631 SSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLE 690 + RT ++ L IS A ++AG Y C+A+ N ++ +++ Sbjct: 3154 AKLEQRTY---GLMDSHAVLQISSAKPSDAGTYVCLAQ-------NALGTAQKQVEVIVD 3203 Query: 691 IRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLI 750 + P QV + LT+ L CS + H++ L Sbjct: 3204 TGAMAPGAP-QVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKL-------------- 3248 Query: 751 LKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLS 810 R+ L ++ + G +L + R DSG Y C+ Sbjct: 3249 --------------------RSPLPWQHRLEGD--TLIIPRVAQQDSGQYICN------- 3279 Query: 811 PNYAWYKLAEEVSGRTEVTV-KQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQ 869 A +G E T+ +S + + SV VQL+C+ +T Sbjct: 3280 --------ATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLT-- 3329 Query: 870 LMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVA 929 F W SR + G A+N L LH E +P Sbjct: 3330 -----FQW-------------SRVGSSLPGRATARNEL---LHFERAAP----------- 3357 Query: 930 VQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAA 989 +DSG Y C V + S + G T + ++ V T S A+ Sbjct: 3358 -EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGAS 3416 Query: 990 FQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1020 + C++ S D + W+ K GG+ Sbjct: 3417 VEFHCAVPS----DRGTQLRWF----KEGGQ 3439 Score = 45.4 bits (106), Expect = 3e-04 Identities = 106/536 (19%), Positives = 181/536 (33%), Gaps = 146/536 (27%) Query: 77 SSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAK 136 S P+ I T RGG + R Q + L I + D+GEY CH + G+ S + Sbjct: 2559 SQAPHTI-TWYKRGGSL-PSRHQIVGSRLRIPQVTPADSGEYVCHVSN------GAGSRE 2610 Query: 137 MNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVI 196 +L+V ++ +P P+ + E +S T+ L V +P +I Sbjct: 2611 TSLIVTIQGSGSSHVPSV-----SPPIRI--ESSSPTVVEGQ--TLDLNCVVARQPQAII 2661 Query: 197 SLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPD 256 + + S ++ Q+ G L + + +D GE+ C A I + Sbjct: 2662 TWYK----RGGSLPSRHQTHGS-----------HLRLHQMSVADSGEYVCRANNNIDALE 2706 Query: 257 GSWYAMTRKRSEGAVVNVQPT-------DKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309 S V++V P+ +R+E+ GE ++ C++ Q Sbjct: 2707 AS-----------IVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQ-- 2753 Query: 310 PDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQE 369 + V+W + + H + RG L+++H+ Sbjct: 2754 --AHAQVTWHKRGGSLPS--------------HHQTRGSR-----------LRLHHVSPA 2786 Query: 370 DSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIV-LPLTDNWVVKVPQHHQLLSQGHLE 428 DSG+Y CRV S P ++V + + + V VP Sbjct: 2787 DSGEYVCRV-------------MGSSGPLEASVLVTIEASGSSAVHVPAP---------G 2824 Query: 429 SSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGT 488 + + + ++S + EG+ L C V Q + W R G Sbjct: 2825 GAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQ------------------VTWHKRGGN 2866 Query: 489 VQPGSSYWERSSFGG--VQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI 546 + R G +++ QV P D G+Y C VT ++ + Sbjct: 2867 LP------ARHQVHGPLLRLNQVSP------------ADSGEYSCQVTGSSGTLEASVLV 2908 Query: 547 VGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTW 602 E + PI L + A S VT + DL C++ P VTW Sbjct: 2909 TIEPSSPGPIPAPGLAQPIYIEASS--SHVTEGQTLDLNCVV----PGQAHAQVTW 2958 Score = 36.6 bits (83), Expect = 0.15 Identities = 131/718 (18%), Positives = 237/718 (33%), Gaps = 192/718 (26%) Query: 75 MDSSFPYAIYTQRVRGGKI---FIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFG 131 + S P+ Y R G + +R QG+ LH +Q DAG Y C T + Sbjct: 1700 VSGSPPHYFYWSREDGRPVPSGTQQRHQGSE--LHFPSVQPSDAGVYIC----TCRNLHQ 1753 Query: 132 SYSAKMNLVV--IPDSLQTTAMPQTLHRVEQDPLELT--CEVASETIQHSHLSVAWLRQK 187 S +++ L+V P T + + + + ++T C S++ + ++ W R Sbjct: 1754 SNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAY---TLVWTRLH 1810 Query: 188 VGEKPVEV-------------ISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIF 234 G+ P +S + ++ S+ +A Q + + G + + Sbjct: 1811 NGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSI 1870 Query: 235 H-----LQPSDQGEFYCEAA-------EWIQDPDGSWYAMTRKRSEGAVVN---VQPTDK 279 H +QP EF C A EW P G A + + G ++ V+PTD Sbjct: 1871 HPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPA--KAQIHGGILRLPAVEPTD- 1927 Query: 280 EFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVS---WAFNSSLIATMGPNAVPVL 336 + + R H+ R +L VS ++ + A V Sbjct: 1928 ----QAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVP 1983 Query: 337 NSEFAHREARGQL--KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394 ++ R+ G L + E + L I + D+G Y C T T Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQA------- 2036 Query: 395 KRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSV 454 I ++VL +D S V++ S++ + EG+ L +C V Sbjct: 2037 ----RIQVVVLSASD------------------ASPPPVKIESSSPSVTEGQTLDLNCVV 2074 Query: 455 RTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSF 514 + Q + W R G++ P + + +++ QV P Sbjct: 2075 AGSAHAQ------------------VTWYRRGGSLPPHT----QVHGSRLRLPQVSP--- 2109 Query: 515 SLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTP 574 D G+Y C V G I+++ L + + + P Sbjct: 2110 ---------ADSGEYVCRVEN------------GSGPKEASITVSVLHGTHSGPSYTPVP 2148 Query: 575 G-------------VTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRD 621 G V + DL C++ P VTW + Sbjct: 2149 GSTRPIRIEPSSSHVAEGQTLDLNCVV----PGQAHAQVTWH----------------KR 2188 Query: 622 GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRL 681 GG ++ ++ L + + + ++G+Y C + T L Sbjct: 2189 GG--------------SLPARHQTHGSLLRLHQVTPADSGEYVC-------HVVGTSGPL 2227 Query: 682 AERTSNLLEIRVLQ-PVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWY 738 +E V+ P+ +++ S + T+ E + + L+C V Q +H V WY Sbjct: 2228 EASVLVTIEASVIPGPIPPVRIESS--SSTVAEGQTLDLSCVVAGQ----AHAQVTWY 2279 >gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens] Length = 191 Score = 46.2 bits (108), Expect = 2e-04 Identities = 27/95 (28%), Positives = 42/95 (44%) Query: 712 VENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 771 +E + L C V + ++S AV W+ D+ L++K T +Y R Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96 Query: 772 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEE 806 RL+ G L+ L+V + SD G Y C V+E Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 35.0 bits (79), Expect = 0.43 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%) Query: 849 LETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 908 LE L C V + S L V WF + + ++++ Y +++ + Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96 Query: 909 GRLHL-ESPSPGVYRLFIQNVAVQDSGTYSCHVEE 942 RL L E +YRL + + D G Y C V+E Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 34.7 bits (78), Expect = 0.57 Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%) Query: 145 SLQTTAMP-QTLHRVEQDPLELTCEVASETIQHSHLSVAWL-RQKVGEKPVEVISLSRDF 202 +L T P + +E + L C V+ + + S L+V W + ++ +++ Sbjct: 23 ALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLR 82 Query: 203 MLHSSSEYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCEAAE 250 ++ +++ +RL + R +RL++ LQPSDQG + C E Sbjct: 83 VVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 32.3 bits (72), Expect = 2.8 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 295 GEPVEFRCILEAQNVPDRYFAVSWAFNSS------LIATMGPNAVPVLNSEFAHREARGQ 348 GE C + + D AV W F S L+ M V F+ R + Sbjct: 39 GENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRR 98 Query: 349 LKVAKES-DSVFVLKIYHLRQEDSGKYNCRVTE 380 L++ +E +++ L + L+ D G Y CRV E Sbjct: 99 LRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 32.3 bits (72), Expect = 2.8 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 1082 LYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESA 1122 LYRL+VL P D G+Y C V+E + + +W + SA Sbjct: 109 LYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTAWSNGSSA 148 >gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo sapiens] Length = 320 Score = 46.2 bits (108), Expect = 2e-04 Identities = 27/95 (28%), Positives = 42/95 (44%) Query: 712 VENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 771 +E + L C V + ++S AV W+ D+ L++K T +Y R Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96 Query: 772 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEE 806 RL+ G L+ L+V + SD G Y C V+E Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 35.0 bits (79), Expect = 0.43 Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 6/140 (4%) Query: 145 SLQTTAMP-QTLHRVEQDPLELTCEVASETIQHSHLSVAWL-RQKVGEKPVEVISLSRDF 202 +L T P + +E + L C V+ + + S L+V W + ++ +++ Sbjct: 23 ALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLR 82 Query: 203 MLHSSSEYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYA 261 ++ +++ +RL + R +RL++ LQPSDQG + C E I W A Sbjct: 83 VVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTA 141 Query: 262 MTRKRS--EGAVVNVQPTDK 279 + S E V++++ +++ Sbjct: 142 WSNGSSATEMRVISLKASEE 161 Score = 35.0 bits (79), Expect = 0.43 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%) Query: 849 LETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 908 LE L C V + S L V WF + + ++++ Y +++ + Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96 Query: 909 GRLHL-ESPSPGVYRLFIQNVAVQDSGTYSCHVEE 942 RL L E +YRL + + D G Y C V+E Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 Score = 33.9 bits (76), Expect = 0.97 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Query: 1082 LYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICS 1141 LYRL+VL P D G+Y C V+E + + +W + SA +RV+ + +S Sbjct: 109 LYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTAWSNGSSA-TEMRVISLKASEESSFEK 166 Query: 1142 ND---ALFYFVFFYPFPIFGILIITILL 1166 A F ++ Y + + I++ILL Sbjct: 167 TKETWAFFEDLYVYAVLVCCVGILSILL 194 Score = 32.3 bits (72), Expect = 2.8 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 295 GEPVEFRCILEAQNVPDRYFAVSWAFNSS------LIATMGPNAVPVLNSEFAHREARGQ 348 GE C + + D AV W F S L+ M V F+ R + Sbjct: 39 GENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRR 98 Query: 349 LKVAKES-DSVFVLKIYHLRQEDSGKYNCRVTE 380 L++ +E +++ L + L+ D G Y CRV E Sbjct: 99 LRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131 >gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens] Length = 585 Score = 45.4 bits (106), Expect = 3e-04 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 2/75 (2%) Query: 972 SLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEE 1031 S +++T A + ++A +LDC ++ ++ S T + + +P ++EE Sbjct: 316 SFEIETEPQAAVLHLQSAEELDCQ--GEEEEEEEDGSSFCSGVTDSSTQSLAPSESDEEE 373 Query: 1032 EREEEEEEDDDDDDD 1046 E EEEEEE++DDDDD Sbjct: 374 EEEEEEEEEEDDDDD 388 >gi|31377806 polymeric immunoglobulin receptor precursor [Homo sapiens] Length = 764 Score = 45.1 bits (105), Expect = 4e-04 Identities = 90/411 (21%), Positives = 151/411 (36%), Gaps = 70/411 (17%) Query: 7 VLSCL-AVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65 VL+CL AV +S + + E + EG+ ++I C Y P+ N Y Sbjct: 5 VLTCLLAVFPAISTKSPIFGPE-EVNSVEGNSVSITC----YYPPTSVNRHTRKYWCRQG 59 Query: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNST-LLHITDLQARDAGEYECHTPS 124 R I + + Y G+ + N T +++I L D+G Y+C Sbjct: 60 ARGGCITLISSEGYVSSKYA-----GRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGI 114 Query: 125 TDKQYFGSYSAKMNLVVIPDSLQTTAMPQT-LHRVEQDPLELTCEVASETIQHSHLSVAW 183 + S+ + + P L T + L R + + C +E Q Sbjct: 115 NSRGL--SFDVSLEVSQGPGLLNDTKVYTVDLGRT----VTINCPFKTENAQKRKS---- 164 Query: 184 LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLD--KLGRTTFRLTIFHLQPSDQ 241 L +++G PV VI SS Y G +RLD G+ F + I L+ SD Sbjct: 165 LYKQIGLYPVLVID---------SSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDA 215 Query: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301 G++ C+A + D + + +K ++ V+ +P E + V F Sbjct: 216 GQYLCQAGD---DSNSN-----KKNADLQVLKPEP-----------ELVYEDLRGSVTFH 256 Query: 302 CIL--EAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVF 359 C L E NV S N ++ P L ++ D F Sbjct: 257 CALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRI--------LLNPQDKDGSF 308 Query: 360 VLKIYHLRQEDSGKYNCRVTEREKTVTGE-------FIDKESKRPKNIPII 403 + I LR+ED+G+Y C + G F+++ES P++ ++ Sbjct: 309 SVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVV 359 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 44.3 bits (103), Expect = 7e-04 Identities = 191/1005 (19%), Positives = 347/1005 (34%), Gaps = 217/1005 (21%) Query: 67 REVQIVSTMDSSFPYAIYTQRVRG------GKIFIERVQGNSTLLHITDLQARDAGEYEC 120 +EVQ+ +T++ + P ++ + +G I+I + +TL + ++ +AG+Y C Sbjct: 7507 KEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL-QFSRVEPANAGKYTC 7565 Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 K G L V+ + P+++ D L C VA LS Sbjct: 7566 QI----KNDAGMQECFATLSVL-EPATIVEKPESIKVTTGDTCTLECTVAGTP----ELS 7616 Query: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240 W + G++ L S ++Y ++ + + L I ++ PSD Sbjct: 7617 TKWFKD--GKE------------LTSDNKY---------KISFFNKVS-GLKIINVAPSD 7652 Query: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300 G + E +Q+P G + ++Q +D+ TV ++L Sbjct: 7653 SGVYSFE----VQNPVGK---------DSCTASLQVSDR--TVPPSFTRKLKETNGLSGS 7697 Query: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360 ++E + +VSW + I++ G+ +D+ Sbjct: 7698 SVVMECKVYGSPPISVSWFHEGNEISS-------------------GRKYQTTLTDNTCA 7738 Query: 361 LKIYHLRQEDSGKYNCRVTER----EKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVP 416 L + L + DSG Y C T E + + S K P+ VL T+ + Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 7798 Query: 417 QHHQLLSQGHLESSISVEVASNASVILE-------------GEDLRFSCSVRT-AGRPQG 462 + S + S + +V LE + ++C V AG+ Sbjct: 7799 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 7858 Query: 463 RFSVIWQLVDRQNRRSNIMWLDR------DGT---VQPGSSYWERSSFGGVQMEQVQ--- 510 + + + +R N +++ +GT P S W+++ ++ Sbjct: 7859 TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITT 7918 Query: 511 -PNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTA 569 S L I +S ED GQY C++ + S I LE + V Sbjct: 7919 TEKSAILEIPSSTVEDAGQYNCYIEN------------ASGKDSCSAQILILEPPYFVKQ 7966 Query: 570 ISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDR 629 + V+ DS LQC Q GT E GV W Sbjct: 7967 LEPVK-VSVGDSASLQC------------------QLAGTPEI----------GVSWYKG 7997 Query: 630 SSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLL 689 + R T + +N L ++ ++G+Y C AE N+ ++ T + Sbjct: 7998 DTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE-------NSVGEVSASTFLTV 8050 Query: 690 EIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVH-KPSDADGK 748 + + L P Q+ + T+ L P+ +C++ S + +V WY KP Sbjct: 8051 QEQKLPPSFSRQLRDVQETVGL----PVVFDCAI----SGSEPISVSWYKDGKPLKDSPN 8102 Query: 749 L------------ILKTTHNSAFEYGTYAE----EEGLRARLQFERHVSGGLFSLTVQ-- 790 + I KT + A +Y A ARL + F + + Sbjct: 8103 VQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPV 8162 Query: 791 RAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEV--SGRTEVTVKQPDSRLRLSQAQGNLSV 848 A V +S + CHV +W K + E+ G+ +++ + + L + L V Sbjct: 8163 DAVVGESADFECHV-TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV------LKV 8215 Query: 849 LETRQVQLECVVLN---RTSITSQLMVEWFVWKPNHPER--ETVARLSRDATFHYGEQAA 903 + Q C +N + S T+QL ++ + P+ +R ETV ++ G A Sbjct: 8216 DKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAG 8275 Query: 904 KNNL-----KGRLHLESPS-------PGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMW 951 + K + ++ S L ++ + D+G Y+C V Sbjct: 8276 SQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVS---------- 8325 Query: 952 YKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI 996 A +++ + P D + TVSE QL C + Sbjct: 8326 -NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHV 8369 Score = 38.1 bits (87), Expect = 0.051 Identities = 65/307 (21%), Positives = 117/307 (38%), Gaps = 78/307 (25%) Query: 8 LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSS--- 64 +S A +V +R V+++ L + ++ T C VS G + ++ P S Sbjct: 5277 ISTSAKYRLVCHERSVSLEVNNLELEDTANYT--CKVSNVAGDDACSGILTVKEPPSFLV 5334 Query: 65 --------PEREVQIVSTMDSSFPYAIY-----TQRVRGGKIFIERVQGNSTLLHITDLQ 111 P+ V+ + + + P+ I + V G K FI ++G+++ L++ + Sbjct: 5335 KPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIG-LEGSTSFLNLYSVD 5393 Query: 112 ARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQ-------DPLE 164 A G+Y CH + GS S L+V T P+ + ++E D Sbjct: 5394 ASKTGQYTCHVTND----VGSDSCTTMLLV-------TEPPKFVKKLEASKIVKAGDSSR 5442 Query: 165 LTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR--QSLGEVRLD 222 L C++A G + V+ + L +S +Y S+ ++++ Sbjct: 5443 LECKIA------------------GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 5484 Query: 223 KLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFT 282 +L D G+F CEA Q+P GS T+ +V P F Sbjct: 5485 ------------NLSTEDSGDFICEA----QNPAGSTSCSTK-----VIVKEPPVFSSFP 5523 Query: 283 VRLETEK 289 +ET K Sbjct: 5524 PIVETLK 5530 Score = 37.7 bits (86), Expect = 0.067 Identities = 110/549 (20%), Positives = 186/549 (33%), Gaps = 140/549 (25%) Query: 289 KRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQ 348 +RL G + CILE + +V+W + I + G Sbjct: 5804 RRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVS-------------------GA 5844 Query: 349 LKVAKESDSVFVLKIYHLRQEDSGKYNCRVT------EREKTVTGEFIDKESKRPKNIPI 402 SD+V L++ L D G Y C E +T + K P+ + + Sbjct: 5845 KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEV 5904 Query: 403 I-------------VLPLTDNW------VVKVPQHHQLLSQGHLES---SISVEVASNAS 440 + P NW +VK + + E +I + + + Sbjct: 5905 LPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 5964 Query: 441 VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR--QNRRSNIMWLDRDGTVQPGSSYWER 498 ++ + SC+ R + F + +L D + +S I+ GT+ P S W++ Sbjct: 5965 CVVSNNAGQASCTTRLFVKEPAAF--LKRLSDHSVEPGKSIILESTYTGTL-PISVTWKK 6021 Query: 499 SSFGGVQMEQVQ----PNSFSLGIFNSRKEDEGQYECHV-TEWVRAVDGEWQIVGERRAS 553 F E+ + L I NS K D GQY C + E R V G Sbjct: 6022 DGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCG----------- 6070 Query: 554 TPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFH 613 ++ LE + VT + DS LQC Q GT E Sbjct: 6071 --ALVSTLEPPYFVTELEPLEAAV-GDSVSLQC------------------QVAGTPEI- 6108 Query: 614 DLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKN 673 V W + R ++N L ++ + ++G+Y C AE Sbjct: 6109 ---------TVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAE----- 6154 Query: 674 YNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHF 733 N+ + +T ++ R L P Q+ ++T+ L P+ L C + ++ Sbjct: 6155 --NSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGL----PVTLTCRLNG----SAPI 6204 Query: 734 AVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAE 793 V WY DG L+ ++E L+ F +V+ +L + + + Sbjct: 6205 QVCWY------RDGVLL--------------RDDENLQT--SFVDNVA----TLKILQTD 6238 Query: 794 VSDSGSYYC 802 +S SG Y C Sbjct: 6239 LSHSGQYSC 6247 Score = 36.6 bits (83), Expect = 0.15 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 100 GNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVE 159 G LHI D+Q DAGEY C +K+ + +AK+ + +P T + + + V+ Sbjct: 11170 GKDRKLHIIDVQLSDAGEYTCVLRLGNKE--KTSTAKLVVEELPVRFVKT-LEEEVTVVK 11226 Query: 160 QDPLELTCEVASETIQHSHLSVAWLR--QKVGEKPVEVI 196 PL L+CE+ E V W + + V EKP ++ Sbjct: 11227 GQPLYLSCELNKER------DVVWRKDGKIVVEKPGRIV 11259 Score = 35.8 bits (81), Expect = 0.25 Identities = 56/260 (21%), Positives = 95/260 (36%), Gaps = 28/260 (10%) Query: 758 AFEYGTYAEEEGLRARLQFERHVSG-GLFSLTVQRAEVSDSGSYYCHV-------EEWLL 809 A E Y + + L+ F+ H S G + L + SD G Y C + + L Sbjct: 32746 AKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQ 32805 Query: 810 SPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSI 866 A+ + E+VS +E K+ D + S + + V+ L T++ Sbjct: 32806 FMGQAFKSIHEKVSKISE--TKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTV 32863 Query: 867 TSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQ 926 +S + ++ V P + + K +G + S G + L I Sbjct: 32864 SSDSVAKFAVKATGEPRPTAI-----------WTKDGKAITQGGKYKLSEDKGGFFLEIH 32912 Query: 927 NVAVQDSGTYSCHVEEWLPSPSG---MWYKRAEDTAGQTALTVMRPDASLQVDTVVPNAT 983 DSG Y+C V+ S S + K +DT Q T + + Q VV Sbjct: 32913 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVV-QEE 32971 Query: 984 VSEKAAFQLDCSIVSRSSQD 1003 +S+KA + + SQ+ Sbjct: 32972 ISQKALRSEEIKMSEAKSQE 32991 Score = 35.0 bits (79), Expect = 0.43 Identities = 36/166 (21%), Positives = 70/166 (42%), Gaps = 11/166 (6%) Query: 228 TFRLTIFHLQPSDQGEFYCE-------AAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKE 280 T+ L I +L SDQGE+ CE + +Q ++ ++ K S+ + + +D++ Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK--ISETKKSDQK 32830 Query: 281 FTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEF 340 T T K EP+ + ++ + D + ++ AT P + + Sbjct: 32831 TTESTVTRKTEPKAPEPISSKPVI-VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG 32889 Query: 341 AHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVT 386 G+ K++++ F L+I+ DSG Y C V +V+ Sbjct: 32890 KAITQGGKYKLSEDKGG-FFLEIHKTDTSDSGLYTCTVKNSAGSVS 32934 Score = 33.9 bits (76), Expect = 0.97 Identities = 32/132 (24%), Positives = 63/132 (47%), Gaps = 11/132 (8%) Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNSTLLHITDLQARDAGEYECHT 122 S + E + T +A ++ +R GGK I ++ NS L + + D+G+Y C+ Sbjct: 8169 SADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLE-NSAHLTVLKVDKGDSGQYTCY- 8226 Query: 123 PSTDKQYFGSYSAKMNLV--VIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180 + ++ S +A++N+ +IP S T + +T+ E + +L VA ++ Sbjct: 8227 -AVNEVGKDSCTAQLNIKERLIPPSF-TKRLSETVEETEGNSFKLEGRVAGS----QPIT 8280 Query: 181 VAWLRQKVGEKP 192 VAW + + +P Sbjct: 8281 VAWYKNNIEIQP 8292 Score = 31.6 bits (70), Expect = 4.8 Identities = 67/354 (18%), Positives = 122/354 (34%), Gaps = 80/354 (22%) Query: 696 PVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTH 755 PVT + + +T++E + + L C + S V W Sbjct: 939 PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSP----TVTW------------------ 976 Query: 756 NSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHV--EEWLLSPN- 812 Y E+ + + + F+ G+ L ++ A DSG + C E +S + Sbjct: 977 --------YREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSC 1028 Query: 813 YAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMV 872 Y +++EE T ++ + E R V+ VV+ TS+T + Sbjct: 1029 YLAVQVSEEFEKETTAVTEK-------------FTTEEKRFVESRDVVMTDTSLTEEQAG 1075 Query: 873 EWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQD 932 P + V +L + +G Q N P P VY + Sbjct: 1076 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGN----------PKPHVY--------WKK 1117 Query: 933 SGTYSCHVEEWLPSPSGMWYKRA-EDTAGQTALTVMR--PDASLQVDTVVPN----ATVS 985 SG +P +G YK + G+ L + D + + VV N + S Sbjct: 1118 SG---------VPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168 Query: 986 EKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEE 1039 + D ++ +S Q+ + + + ++PG E E+E E+E+ Sbjct: 1169 ASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQ 1222 Score = 31.6 bits (70), Expect = 4.8 Identities = 66/283 (23%), Positives = 107/283 (37%), Gaps = 60/283 (21%) Query: 718 QLNCSVKSQTSQNSHFAVL--WYVHKPSDADGKLILKTTHNSAFEY---GT-------YA 765 QL+ V + TS+ + F ++ KPS L+L+ ++ FE GT Y Sbjct: 4841 QLSNDVGTATSKATLFVKEPPQFIKKPSPV---LVLRNGQSTTFECQITGTPKIRVSWYL 4897 Query: 766 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 825 + + A + GL + + A V +SG+Y C A S Sbjct: 4898 DGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR-----------NDAGTASCS 4946 Query: 826 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERE 885 E+ VK+P + +R + + V++ V+LEC V T V W K N R Sbjct: 4947 IELKVKEPPTFIRELKP---VEVVKYSDVELECEVTG----TPPFEVTWL--KNNREIRS 4997 Query: 886 TVARLSRDATFHYGEQAAKNNLKGRLHLESPSP---GVYRLFIQNVAVQDSGTYSCHVEE 942 + D + LH+ P G Y+ + N + G+ SC Sbjct: 4998 SKKYTLTDRVSVF-----------NLHITKCDPSDTGEYQCIVSN----EGGSCSCSTRV 5042 Query: 943 WLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVS 985 L P + K+ E+T TV++ A+ Q TV + +S Sbjct: 5043 ALKEPPS-FIKKIENTT-----TVLKSSATFQ-STVAGSPPIS 5078 Score = 31.6 bits (70), Expect = 4.8 Identities = 39/180 (21%), Positives = 72/180 (40%), Gaps = 43/180 (23%) Query: 626 WGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERT 685 W S+ R + +L I ++AG+Y CV L K +T + E Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE- 11209 Query: 686 SNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDA 745 L +R ++ + + +T+V+ +P+ L+C + N V+W Sbjct: 11210 ---LPVRFVKTL--------EEEVTVVKGQPLYLSCEL------NKERDVVW------RK 11246 Query: 746 DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE 805 DGK+++ E+ G + V G + +LT+ A+ +D+G+Y VE Sbjct: 11247 DGKIVV--------------EKPG-----RIVPGVIGLMRALTINDADDTDAGTYTVTVE 11287 Score = 31.2 bits (69), Expect = 6.3 Identities = 59/298 (19%), Positives = 105/298 (35%), Gaps = 56/298 (18%) Query: 764 YAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVS 823 Y + LR ++ H + +L + +++DSG Y C E EVS Sbjct: 7995 YKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE-----------NSVGEVS 8043 Query: 824 GRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP- 882 T +TV++ S+ ++ V +C + S + + V W+ K P Sbjct: 8044 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI----SGSEPISVSWY--KDGKPL 8097 Query: 883 ----------------------ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGV 920 +R + S AT G ++ L + E +P Sbjct: 8098 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL---ILTEGKNPPF 8154 Query: 921 Y--RLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAED--TAGQTALTVMRPDASLQVD 976 + RL + V +S + CHV P W K + + + G+ ++ + A L V Sbjct: 8155 FDIRLAPVDAVVGESADFECHVTGTQPIKVS-WAKDSREIRSGGKYQISYLENSAHLTV- 8212 Query: 977 TVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEERE 1034 V + + Q C V+ +DS A +++ + + L E EE E Sbjct: 8213 -----LKVDKGDSGQYTCYAVNEVGKDS--CTAQLNIKERLIPPSFTKRLSETVEETE 8263 Score = 30.8 bits (68), Expect = 8.2 Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 32/191 (16%) Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123 S + E + ++ + +R G + GN+ L I + D+G+Y C Sbjct: 6287 SADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ-- 6344 Query: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183 +T+ SA++++ P ++ + + E ++L C+++ + V+W Sbjct: 6345 ATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGES--IQLECKISGS----PEIKVSW 6398 Query: 184 LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGE 243 R D LH S +Y + V L LTI D G+ Sbjct: 6399 FR--------------NDSELHESWKY-NMSFINSVAL---------LTINEASAEDSGD 6434 Query: 244 FYCEAAEWIQD 254 + CEA + D Sbjct: 6435 YICEAHNGVGD 6445 Score = 30.8 bits (68), Expect = 8.2 Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 48/251 (19%) Query: 775 QFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPD 834 +++ ++ +LTV E SDSG Y C ++ N A ++E S +TV++P Sbjct: 7727 KYQTTLTDNTCALTVNMLEESDSGDYTC------IATNMAG---SDECS--APLTVREPP 7775 Query: 835 SRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVW--------KPNHPERET 886 S Q + VL V +V T V WF + N ++ Sbjct: 7776 S---FVQKPDPMDVLTGTNVTFTSIVKG----TPPFSVSWFKGSSELVPGDRCNVSLEDS 7828 Query: 887 VARL---------SRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQD----S 933 VA L S + T +A K + L++++P+ V RL ++ Sbjct: 7829 VAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILE 7888 Query: 934 GTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLD 993 GT++ P S W K + + + S ++ +P++TV + A Q + Sbjct: 7889 GTFT-----GTPPISVTWKKNGINVTPSQRCNITTTEKSAILE--IPSSTVED--AGQYN 7939 Query: 994 CSIVSRSSQDS 1004 C I + S +DS Sbjct: 7940 CYIENASGKDS 7950 >gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo sapiens] Length = 120 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 5/122 (4%) Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60 M C + +L +A AQ Q+ VQ G + G+ + + C VSGY +E + W Sbjct: 1 MDCTWRILFLVAAATGTHAQVQL-VQSGAEVKKPGASVKVSCKVSGYT-LTELSMHW--- 55 Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 + +P + ++ + D IY Q+ +G E ++ + ++ L++ D Y C Sbjct: 56 VRQAPGKGLEWMGGFDPEDGETIYAQKFQGRVTMTEDTSTDTAYMELSSLRSEDTAVYYC 115 Query: 121 HT 122 T Sbjct: 116 AT 117 >gi|14150145 matrix-remodelling associated 8 [Homo sapiens] Length = 442 Score = 42.4 bits (98), Expect = 0.003 Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 28/216 (12%) Query: 737 WYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV-SGGLFSLTVQRAEVS 795 W + P + +L SA E Y + R RL+ G FSL ++ E + Sbjct: 75 WDLRGPGGGPARRLLDLY--SAGEQRVYEARD--RGRLELSASAFDDGNFSLLIRAVEET 130 Query: 796 DSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQ 855 D+G Y C++ ++ + L E ++ R EVT P + + L+V Sbjct: 131 DAGLYTCNL-------HHHYCHLYESLAVRLEVTDGPPATPAYWDGEKEVLAVARGAPAL 183 Query: 856 LECVVLNRTSI-------TSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 908 L CV NR + +Q +V W P P L A+ GE+ A L Sbjct: 184 LTCV--NRGHVWTDRHVEEAQQVVHWDRQPPGVPHDRADRLLDLYAS---GERRAYGPLF 238 Query: 909 GR----LHLESPSPGVYRLFIQNVAVQDSGTYSCHV 940 R + ++ G + L I+ + V D GTYSCH+ Sbjct: 239 LRDRVAVGADAFERGDFSLRIEPLEVADEGTYSCHL 274 Score = 42.0 bits (97), Expect = 0.004 Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 23/183 (12%) Query: 634 RTRTAIEKAESS---NNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLE 690 R R +E + S+ N L I +T+AG Y C N ++ + L E + LE Sbjct: 103 RDRGRLELSASAFDDGNFSLLIRAVEETDAGLYTC-------NLHHHYCHLYESLAVRLE 155 Query: 691 IRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHF-----AVLWYVHKPS-- 743 + P T K L + P L C + + H V W P Sbjct: 156 VTDGPPATPAYWDGEKEVLAVARGAPALLTCVNRGHVWTDRHVEEAQQVVHWDRQPPGVP 215 Query: 744 -DADGKLILKTTHNSAFEYGTYAEEEGLRARLQ-FERHVSGGLFSLTVQRAEVSDSGSYY 801 D +L+ YG + + FER G FSL ++ EV+D G+Y Sbjct: 216 HDRADRLLDLYASGERRAYGPLFLRDRVAVGADAFER----GDFSLRIEPLEVADEGTYS 271 Query: 802 CHV 804 CH+ Sbjct: 272 CHL 274 >gi|45331217 zinc finger protein 526 [Homo sapiens] Length = 670 Score = 41.6 bits (96), Expect = 0.005 Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 4/46 (8%) Query: 1026 LEEQE----EEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGS 1067 LE++E EE EE++EED++DD++ + A+ VG DAV G E + Sbjct: 223 LEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDEST 268 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 41.2 bits (95), Expect = 0.006 Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGP-EGSPWEGRLR 1074 E++EEE EEEEEE+++++++ E A +V V GP GS EG R Sbjct: 747 EDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSER 795 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 40.8 bits (94), Expect = 0.008 Identities = 17/23 (73%), Positives = 20/23 (86%) Query: 1028 EQEEEREEEEEEDDDDDDDPTER 1050 E+EEE EEEEEE+DDDDDD +R Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDR 1071 Score = 38.1 bits (87), Expect = 0.051 Identities = 16/19 (84%), Positives = 17/19 (89%) Query: 1027 EEQEEEREEEEEEDDDDDD 1045 EE+EE EEEEEEDDDDDD Sbjct: 1049 EEEEEAEEEEEEEDDDDDD 1067 Score = 37.4 bits (85), Expect = 0.087 Identities = 15/25 (60%), Positives = 19/25 (76%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERT 1051 EE+E E EEEEE+DDDDD D + + Sbjct: 1050 EEEEAEEEEEEEDDDDDDSDDRDES 1074 Score = 33.5 bits (75), Expect = 1.3 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 10/62 (16%) Query: 998 SRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVG 1057 S SS+ S F SSP E EEE EEE+++++++ ++ S G Sbjct: 1113 SESSESSEFE----------SSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG 1162 Query: 1058 PD 1059 P+ Sbjct: 1163 PE 1164 Score = 32.7 bits (73), Expect = 2.2 Identities = 13/20 (65%), Positives = 16/20 (80%) Query: 1027 EEQEEEREEEEEEDDDDDDD 1046 E EEE E EEEE+++DDDD Sbjct: 1046 ESTEEEEEAEEEEEEEDDDD 1065 Score = 32.3 bits (72), Expect = 2.8 Identities = 12/23 (52%), Positives = 18/23 (78%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 E +EEE EE++++DD DD D +E Sbjct: 1053 EAEEEEEEEDDDDDDSDDRDESE 1075 >gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] Length = 1507 Score = 40.0 bits (92), Expect = 0.013 Identities = 15/23 (65%), Positives = 21/23 (91%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+++E EE+EEEDDD+DDD T+ Sbjct: 1400 EEEDQEEEEQEEEDDDEDDDDTD 1422 Score = 37.4 bits (85), Expect = 0.087 Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 14/109 (12%) Query: 940 VEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSR 999 +EE + SP G ++ T +P A++ V + + K DC + Sbjct: 1322 MEERMKSPFGSSFRTFNATD-------YKPIATIDVKRNIFDLCTDTK-----DCYLAVI 1369 Query: 1000 SSQDSRFAVAWYSLRT--KAGGKRSSPGLEEQEEEREEEEEEDDDDDDD 1046 +Q S A+ ++ + G +R + +E+E++ EEE+EE+DDD+DD Sbjct: 1370 ENQGSMDALNMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDD 1418 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 40.0 bits (92), Expect = 0.013 Identities = 16/40 (40%), Positives = 27/40 (67%) Query: 1018 GGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVG 1057 GG+ S EE+++E E++E+EDDDDD++ + + S G Sbjct: 506 GGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFG 545 Score = 32.0 bits (71), Expect = 3.7 Identities = 13/24 (54%), Positives = 19/24 (79%) Query: 1023 SPGLEEQEEEREEEEEEDDDDDDD 1046 S G EE+EEE EEEEEE + ++++ Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEE 426 Score = 30.8 bits (68), Expect = 8.2 Identities = 12/23 (52%), Positives = 18/23 (78%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EEEEEE+ + +++ E Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEE 428 >gi|158631177 homeodomain leucine zipper protein [Homo sapiens] Length = 550 Score = 40.0 bits (92), Expect = 0.013 Identities = 17/21 (80%), Positives = 18/21 (85%) Query: 1026 LEEQEEEREEEEEEDDDDDDD 1046 L E +EE EEEEEEDDDDDDD Sbjct: 524 LPEDDEEEEEEEEEDDDDDDD 544 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/20 (80%), Positives = 18/20 (90%) Query: 1027 EEQEEEREEEEEEDDDDDDD 1046 E+ EEE EEEEE+DDDDDDD Sbjct: 526 EDDEEEEEEEEEDDDDDDDD 545 Score = 33.9 bits (76), Expect = 0.97 Identities = 13/21 (61%), Positives = 18/21 (85%) Query: 1024 PGLEEQEEEREEEEEEDDDDD 1044 P +E+EEE EEE+++DDDDD Sbjct: 525 PEDDEEEEEEEEEDDDDDDDD 545 Score = 33.5 bits (75), Expect = 1.3 Identities = 16/25 (64%), Positives = 19/25 (76%), Gaps = 5/25 (20%) Query: 1027 EEQEEE-----REEEEEEDDDDDDD 1046 EE+EEE EEEEEE++DDDDD Sbjct: 518 EEEEEELPEDDEEEEEEEEEDDDDD 542 Score = 30.8 bits (68), Expect = 8.2 Identities = 14/33 (42%), Positives = 22/33 (66%), Gaps = 5/33 (15%) Query: 1027 EEQEEERE-----EEEEEDDDDDDDPTERTALL 1054 EE+EEE E EEEEE++++DDD + ++ Sbjct: 516 EEEEEEEELPEDDEEEEEEEEEDDDDDDDDVII 548 >gi|55953110 retinoblastoma protein-binding zinc finger protein isoform c [Homo sapiens] Length = 1481 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/22 (72%), Positives = 20/22 (90%) Query: 1025 GLEEQEEEREEEEEEDDDDDDD 1046 G EE+EEE E+EEEE+DDDDD+ Sbjct: 66 GEEEEEEEEEDEEEEEDDDDDE 87 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/23 (69%), Positives = 20/23 (86%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EE+EEE++DDDDD E Sbjct: 67 EEEEEEEEEDEEEEEDDDDDELE 89 Score = 35.8 bits (81), Expect = 0.25 Identities = 14/21 (66%), Positives = 19/21 (90%) Query: 1026 LEEQEEEREEEEEEDDDDDDD 1046 L E+EEE EEE+EE+++DDDD Sbjct: 65 LGEEEEEEEEEDEEEEEDDDD 85 Score = 34.3 bits (77), Expect = 0.74 Identities = 14/26 (53%), Positives = 20/26 (76%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTA 1052 EE+EE+ EEEE++DDD+ +D E A Sbjct: 71 EEEEEDEEEEEDDDDDELEDEGEEEA 96 Score = 31.6 bits (70), Expect = 4.8 Identities = 11/27 (40%), Positives = 21/27 (77%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTAL 1053 EE+E+E EEE+++DD+ +D+ E ++ Sbjct: 72 EEEEDEEEEEDDDDDELEDEGEEEASM 98 >gi|20336260 retinoblastoma protein-binding zinc finger protein isoform b [Homo sapiens] Length = 1682 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/22 (72%), Positives = 20/22 (90%) Query: 1025 GLEEQEEEREEEEEEDDDDDDD 1046 G EE+EEE E+EEEE+DDDDD+ Sbjct: 267 GEEEEEEEEEDEEEEEDDDDDE 288 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/23 (69%), Positives = 20/23 (86%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EE+EEE++DDDDD E Sbjct: 268 EEEEEEEEEDEEEEEDDDDDELE 290 Score = 35.8 bits (81), Expect = 0.25 Identities = 14/21 (66%), Positives = 19/21 (90%) Query: 1026 LEEQEEEREEEEEEDDDDDDD 1046 L E+EEE EEE+EE+++DDDD Sbjct: 266 LGEEEEEEEEEDEEEEEDDDD 286 Score = 34.3 bits (77), Expect = 0.74 Identities = 14/26 (53%), Positives = 20/26 (76%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTA 1052 EE+EE+ EEEE++DDD+ +D E A Sbjct: 272 EEEEEDEEEEEDDDDDELEDEGEEEA 297 Score = 31.6 bits (70), Expect = 4.8 Identities = 11/27 (40%), Positives = 21/27 (77%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTAL 1053 EE+E+E EEE+++DD+ +D+ E ++ Sbjct: 273 EEEEDEEEEEDDDDDELEDEGEEEASM 299 >gi|20336258 retinoblastoma protein-binding zinc finger protein isoform a [Homo sapiens] Length = 1718 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/22 (72%), Positives = 20/22 (90%) Query: 1025 GLEEQEEEREEEEEEDDDDDDD 1046 G EE+EEE E+EEEE+DDDDD+ Sbjct: 267 GEEEEEEEEEDEEEEEDDDDDE 288 Score = 39.7 bits (91), Expect = 0.018 Identities = 16/23 (69%), Positives = 20/23 (86%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EE+EEE++DDDDD E Sbjct: 268 EEEEEEEEEDEEEEEDDDDDELE 290 Score = 35.8 bits (81), Expect = 0.25 Identities = 14/21 (66%), Positives = 19/21 (90%) Query: 1026 LEEQEEEREEEEEEDDDDDDD 1046 L E+EEE EEE+EE+++DDDD Sbjct: 266 LGEEEEEEEEEDEEEEEDDDD 286 Score = 34.3 bits (77), Expect = 0.74 Identities = 14/26 (53%), Positives = 20/26 (76%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTA 1052 EE+EE+ EEEE++DDD+ +D E A Sbjct: 272 EEEEEDEEEEEDDDDDELEDEGEEEA 297 Score = 31.6 bits (70), Expect = 4.8 Identities = 11/27 (40%), Positives = 21/27 (77%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTERTAL 1053 EE+E+E EEE+++DD+ +D+ E ++ Sbjct: 273 EEEEDEEEEEDDDDDELEDEGEEEASM 299 >gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] Length = 1312 Score = 39.7 bits (91), Expect = 0.018 Identities = 17/23 (73%), Positives = 19/23 (82%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE EEE EEEEEE+D+DDDD E Sbjct: 540 EEAEEEEEEEEEEEDEDDDDNNE 562 Score = 37.7 bits (86), Expect = 0.067 Identities = 16/23 (69%), Positives = 19/23 (82%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 E +EEE EEEEEED+DDDD+ E Sbjct: 541 EAEEEEEEEEEEEDEDDDDNNEE 563 Score = 37.4 bits (85), Expect = 0.087 Identities = 15/23 (65%), Positives = 20/23 (86%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EEEE+EDDDD+++ E Sbjct: 543 EEEEEEEEEEEDEDDDDNNEEEE 565 Score = 34.7 bits (78), Expect = 0.57 Identities = 13/20 (65%), Positives = 18/20 (90%) Query: 1027 EEQEEEREEEEEEDDDDDDD 1046 +E+ EE EEEEEE++D+DDD Sbjct: 539 DEEAEEEEEEEEEEEDEDDD 558 Score = 31.6 bits (70), Expect = 4.8 Identities = 11/23 (47%), Positives = 20/23 (86%) Query: 1027 EEQEEEREEEEEEDDDDDDDPTE 1049 EE+EEE EE+E++DD+++++ E Sbjct: 545 EEEEEEEEEDEDDDDNNEEEEFE 567 >gi|144226847 obscurin-like 1 [Homo sapiens] Length = 1896 Score = 39.3 bits (90), Expect = 0.023 Identities = 50/217 (23%), Positives = 80/217 (36%), Gaps = 57/217 (26%) Query: 63 SSPEREVQIVSTMDSSFPYAIYT--QRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120 ++ ER V FP Y Q+V ++ + ++ G L + + + +D+GE+EC Sbjct: 729 TTSERVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFEC 788 Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQT---LHRVEQDPLELTCEVASETIQHS 177 T +FG V + D P+ +H + + + L CEV E Sbjct: 789 RTEGVSA-FFG--------VTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAP-- 837 Query: 178 HLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQ 237 V W + G++ E S++ ++ G R RL + Q Sbjct: 838 ---VRWYKD--GQEVEE-------------SDFVVLENEGPHR---------RLVLPATQ 870 Query: 238 PSDQGEFYCEAAE--------------WIQDPDGSWY 260 PSD GEF C A + WI P G Y Sbjct: 871 PSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVY 907 Score = 32.3 bits (72), Expect = 2.8 Identities = 47/214 (21%), Positives = 65/214 (30%), Gaps = 59/214 (27%) Query: 111 QARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVA 170 Q D GE+ C + + +A +V P A LH +EL CEVA Sbjct: 1052 QPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHP-----AARSLDLHFGAPGRVELRCEVA 1106 Query: 171 SETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFR 230 Q V W + + + + + L + T Sbjct: 1107 PAGSQ-----VRWYKDGLEVEASDALQLGAE------------------------GPTRT 1137 Query: 231 LTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNV---QPTDKEFTVRLET 287 LT+ H QP D GE+ CE R E NV +P + + Sbjct: 1138 LTLPHAQPEDAGEYVCET-----------------RHEAITFNVILAEPPVQFLALETTP 1180 Query: 288 EKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFN 321 GEPV C L P V W+ N Sbjct: 1181 SPLCVAPGEPVVLSCELSRAGAP-----VVWSHN 1209 Score = 31.6 bits (70), Expect = 4.8 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 13/111 (11%) Query: 91 GKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTA 150 G++ +E+ G +L + ++ DAGEY C P + + S + + ++ + Sbjct: 1313 GRVQLEQA-GARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSE-----L 1366 Query: 151 MPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRD 201 P T+H E D CEV+ V WLR P + ++++ Sbjct: 1367 TPLTVH--EGDDATFRCEVSP-----PDADVTWLRNGAVVTPGPQVEMAQN 1410 >gi|239753214 PREDICTED: similar to hCG2043206 [Homo sapiens] Length = 157 Score = 39.3 bits (90), Expect = 0.023 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 16/113 (14%) Query: 699 KLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSA 758 ++ +++S TL+L + L+C SQ+ +S+ + WY KP A LI Sbjct: 26 EIVMTQSPATLSLSPGERATLSCRA-SQSVSSSYLS--WYQQKPGQAPRLLI-------- 74 Query: 759 FEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSP 811 YG G+ AR F SG F+LT+ + D YYC +++ L P Sbjct: 75 --YGASTRATGIPAR--FSGSGSGTDFTLTISSLQPEDFAVYYCQ-QDYNLPP 122 Score = 35.0 bits (79), Expect = 0.43 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 15/100 (15%) Query: 149 TAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSS 208 T P TL + L+C AS+++ S+LS W +QK G+ P +++ +S Sbjct: 30 TQSPATLSLSPGERATLSCR-ASQSVSSSYLS--WYQQKPGQAP--------RLLIYGAS 78 Query: 209 EYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCE 247 R + R G T F LTI LQP D +YC+ Sbjct: 79 T---RATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQ 115 >gi|169163270 PREDICTED: similar to hCG2043206 [Homo sapiens] Length = 151 Score = 39.3 bits (90), Expect = 0.023 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 16/113 (14%) Query: 699 KLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSA 758 ++ +++S TL+L + L+C SQ+ +S+ + WY KP A LI Sbjct: 21 EIVMTQSPATLSLSPGERATLSCRA-SQSVSSSYLS--WYQQKPGQAPRLLI-------- 69 Query: 759 FEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSP 811 YG G+ AR F SG F+LT+ + D YYC +++ L P Sbjct: 70 --YGASTRATGIPAR--FSGSGSGTDFTLTISSLQPEDFAVYYCQ-QDYNLPP 117 Score = 36.2 bits (82), Expect = 0.19 Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 18/113 (15%) Query: 139 LVVIPDS---LQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEV 195 L+ +PD+ + T P TL + L+C AS+++ S+LS W +QK G+ P Sbjct: 12 LLWLPDTTGEIVMTQSPATLSLSPGERATLSCR-ASQSVSSSYLS--WYQQKPGQAP--- 65 Query: 196 ISLSRDFMLHSSSEYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCE 247 +++ +S R + R G T F LTI LQP D +YC+ Sbjct: 66 -----RLLIYGAST---RATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQ 110 >gi|9624969 butyrophilin-like 2 [Homo sapiens] Length = 455 Score = 38.9 bits (89), Expect = 0.030 Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 30/206 (14%) Query: 58 SIYLPSSPEREVQIVSTMDSSFPYA-IYTQRVRGGKIFI---ERVQGNSTLLHI-TDLQA 112 SI++ E VQ+V T FP +Y + +RG K+ R+Q L + L Sbjct: 149 SIHMEGPGESGVQLVCTARGWFPEPQVYWEDIRGEKLLAVSEHRIQDKDGLFYAEATLVV 208 Query: 113 RDAG--EYEC--HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQ-------D 161 R+A C H P ++ K +++ +P+ LQT ++ Q + Sbjct: 209 RNASAESVSCLVHNPVLTEE-------KGSVISLPEKLQTELASLKVNGPSQPILVRVGE 261 Query: 162 PLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFML-HSSSEYAQRQSLGEVR 220 ++LTC ++ + S + V W R P + + D + +EY R L Sbjct: 262 DIQLTCYLSPKANAQS-MEVRWDRSH--RYPAVHVYMDGDHVAGEQMAEYRGRTVLVSDA 318 Query: 221 LDKLGRTTFRLTIFHLQPSDQGEFYC 246 +D+ GR T L I +PSD G++ C Sbjct: 319 IDE-GRLT--LQILSARPSDDGQYRC 341 Score = 32.0 bits (71), Expect = 3.7 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 5/103 (4%) Query: 429 SSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGT 488 +S+ V S ++ GED++ +C + Q V W DR +R + + DG Sbjct: 244 ASLKVNGPSQPILVRVGEDIQLTCYLSPKANAQS-MEVRW---DRSHRYPAVH-VYMDGD 298 Query: 489 VQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYEC 531 G E + + + +L I ++R D+GQY C Sbjct: 299 HVAGEQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRC 341 Score = 30.8 bits (68), Expect = 8.2 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 6/89 (6%) Query: 158 VEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLG 217 V +D L LTC++ + H+ V W R + P + + RD + + + + + Sbjct: 42 VGEDAL-LTCQLLPKRTT-MHVEVRWYRSE----PSTPVFVHRDGVEVTEMQMEEYRGWV 95 Query: 218 EVRLDKLGRTTFRLTIFHLQPSDQGEFYC 246 E + + + L I ++QPSD G+++C Sbjct: 96 EWIENGIAKGNVALKIHNIQPSDNGQYWC 124 Score = 30.8 bits (68), Expect = 8.2 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 16/80 (20%) Query: 732 HFAVLWYVHKPSDA-----DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFS 786 H V WY +PS DG ++ T EY + E E ++ G + Sbjct: 60 HVEVRWYRSEPSTPVFVHRDG---VEVTEMQMEEYRGWVE--------WIENGIAKGNVA 108 Query: 787 LTVQRAEVSDSGSYYCHVEE 806 L + + SD+G Y+CH ++ Sbjct: 109 LKIHNIQPSDNGQYWCHFQD 128 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,872,546 Number of Sequences: 37866 Number of extensions: 2235704 Number of successful extensions: 25920 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 269 Number of HSP's successfully gapped in prelim test: 160 Number of HSP's that attempted gapping in prelim test: 18023 Number of HSP's gapped (non-prelim): 4933 length of query: 1214 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1100 effective length of database: 13,930,794 effective search space: 15323873400 effective search space used: 15323873400 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.