BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] (755 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] 1588 0.0 gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] 1575 0.0 gi|158138528 l(3)mbt-like 4 [Homo sapiens] 643 0.0 gi|117938328 l(3)mbt-like isoform I [Homo sapiens] 570 e-162 gi|117938330 l(3)mbt-like isoform II [Homo sapiens] 570 e-162 gi|20149698 l(3)mbt-like 2 [Homo sapiens] 182 8e-46 gi|158508476 mbt domain containing 1 [Homo sapiens] 182 8e-46 gi|5174669 sex comb on midleg-like 2 [Homo sapiens] 171 2e-42 gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] 163 5e-40 gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] 152 1e-36 gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens] 138 2e-32 gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens] 138 2e-32 gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens] 138 2e-32 gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens] 138 2e-32 gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens] 74 5e-13 gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 74 5e-13 gi|62953127 polyhomeotic 1-like [Homo sapiens] 70 9e-12 gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens] 70 9e-12 gi|148612879 polyhomeotic like 3 [Homo sapiens] 65 2e-10 gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] 63 1e-09 gi|197927257 sterile alpha motif domain containing 13 isoform 2 ... 52 3e-06 gi|197927255 sterile alpha motif domain containing 13 isoform 2 ... 52 3e-06 gi|58293756 sterile alpha motif domain containing 13 isoform 1 [... 52 3e-06 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 8e-06 gi|158508495 sex comb on midleg-like 4 [Homo sapiens] 44 6e-04 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 40 0.006 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 40 0.008 gi|18034775 PHD finger protein 20 [Homo sapiens] 40 0.010 gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 39 0.018 gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 39 0.018 >gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] Length = 755 Score = 1588 bits (4113), Expect = 0.0 Identities = 755/755 (100%), Positives = 755/755 (100%) Query: 1 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA 60 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA Sbjct: 1 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA 60 Query: 61 TTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCAR 120 TTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCAR Sbjct: 61 TTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCAR 120 Query: 121 HIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRG 180 HIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRG Sbjct: 121 HIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRG 180 Query: 181 SQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK 240 SQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK Sbjct: 181 SQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK 240 Query: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKT 300 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKT Sbjct: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKT 300 Query: 301 GHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNP 360 GHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNP Sbjct: 301 GHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNP 360 Query: 361 SFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNV 420 SFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNV Sbjct: 361 SFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNV 420 Query: 421 KHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRV 480 KHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRV Sbjct: 421 KHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRV 480 Query: 481 KVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKG 540 KVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKG Sbjct: 481 KVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKG 540 Query: 541 IGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNKRTDANESSSS 600 IGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNKRTDANESSSS Sbjct: 541 IGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNKRTDANESSSS 600 Query: 601 PEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQQAQRRSAVFLSFKSPIPCLPL 660 PEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQQAQRRSAVFLSFKSPIPCLPL Sbjct: 601 PEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQQAQRRSAVFLSFKSPIPCLPL 660 Query: 661 RWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQ 720 RWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQ Sbjct: 661 RWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQ 720 Query: 721 TDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL 755 TDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL Sbjct: 721 TDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL 755 >gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] Length = 780 Score = 1575 bits (4077), Expect = 0.0 Identities = 755/780 (96%), Positives = 755/780 (96%), Gaps = 25/780 (3%) Query: 1 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA 60 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA Sbjct: 1 MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA 60 Query: 61 TTTWMVPTAQE-------------------------VFSEKTGMPFRLKDPVKVEGLQFC 95 TTTWMVPTAQE VFSEKTGMPFRLKDPVKVEGLQFC Sbjct: 61 TTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFC 120 Query: 96 ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK 155 ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK Sbjct: 121 ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK 180 Query: 156 ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE 215 ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE Sbjct: 181 ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE 240 Query: 216 EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG 275 EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG Sbjct: 241 EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG 300 Query: 276 YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE 335 YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE Sbjct: 301 YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE 360 Query: 336 NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS 395 NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS Sbjct: 361 NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS 420 Query: 396 PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK 455 PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK Sbjct: 421 PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK 480 Query: 456 LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL 515 LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL Sbjct: 481 LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL 540 Query: 516 QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL 575 QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL Sbjct: 541 QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL 600 Query: 576 SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE 635 SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE Sbjct: 601 SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE 660 Query: 636 PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL 695 PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL Sbjct: 661 PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL 720 Query: 696 PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL 755 PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL Sbjct: 721 PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL 780 >gi|158138528 l(3)mbt-like 4 [Homo sapiens] Length = 623 Score = 643 bits (1658), Expect = 0.0 Identities = 324/628 (51%), Positives = 419/628 (66%), Gaps = 57/628 (9%) Query: 159 KEDGEERDDEMENK----QDVRILRGSQRARRKRRGDSAVLKQGLPPKGKK-AWCWASYL 213 K+ +R M++K QD R+ Q K+ DS +P + AW W YL Sbjct: 2 KQPNRKRKLNMDSKERLDQDGRL---EQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYL 58 Query: 214 EEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHF 273 +E+KAVA P +LF + QSFP ++NGF++GM+LEG+DP H SV+CVL+VAEVCGYR++LHF Sbjct: 59 KEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHF 118 Query: 274 DGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSL 333 DGY CYDFW NA + DIHPVGWCEKT H+LH PKGY++++F W YLK CK Q APK L Sbjct: 119 DGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKL 178 Query: 334 FENQNITVIPSG-----FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYD 388 F N++ P+G F+VGMKLEAVD+KNPS +CVAT+ D+V++R LVHFDNWD+SYD Sbjct: 179 FRNRS----PNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYD 234 Query: 389 YWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPH 448 YWC+ +SP++ PVGWC+E+ RTLI P GYPN ++FSW +YLE T + PA+ FK++ PH Sbjct: 235 YWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPH 294 Query: 449 GFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWC 508 GF MKLEVVDKRNP IRVAT+ D DD RVKVHFDGW++ YDYW++ADSPDIHP+GWC Sbjct: 295 GFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWC 354 Query: 509 SKTGHPLQPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKD 568 TGHPL+ P +L C TPGC+GIGH + R+ G HSA CPYS++NL K+ Sbjct: 355 DVTGHPLEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKE 414 Query: 569 RIFPDRLSGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVK-EDFEERTESEMRTSH 627 DRL ++T AN S S + + + E+ S+ R Sbjct: 415 ATLHDRL-------------REQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQ 461 Query: 628 EA-----RGARE-----------------EPTVQQAQR--RSAVFLSFKS--PIPCLPLR 661 +A +G + E +V+QAQ+ +V +S S P LPL Sbjct: 462 QAKCLKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLG 521 Query: 662 WEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQT 721 EQ KLLP VA I AS+V++W+ DEV+EF+QSL GCEEH K FK EQIDG+AFLL+TQT Sbjct: 522 REQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQT 581 Query: 722 DIVKIMSIKLGPALKIFNSILMFKAAEK 749 DIVK+M IKLGPALKI+NSILMF+ +++ Sbjct: 582 DIVKVMKIKLGPALKIYNSILMFRHSQE 609 >gi|117938328 l(3)mbt-like isoform I [Homo sapiens] Length = 772 Score = 570 bits (1468), Expect = e-162 Identities = 291/611 (47%), Positives = 370/611 (60%), Gaps = 59/611 (9%) Query: 129 EERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDE---MENKQDVRILRGSQRAR 185 +ER V +N S KP K + E + E ME +++ + G A Sbjct: 126 QERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAMEKQEEGKDPEGQPTAS 185 Query: 186 RKRRGDSAVLKQGLPPKGKK--AWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGM 243 +S P G+K W W SYLEE+KA+ P LF++ Q+ +NKNGFK+GM Sbjct: 186 TP---ESEEWSSSQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGM 242 Query: 244 KLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHK 303 KLEG+DP+H S+Y +LTVAEVCGYR++LHFDGYS+C+DFWVNA++ DIHP GW EKTGHK Sbjct: 243 KLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHK 302 Query: 304 LHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFI 363 L PPKGYKEEEF+W YL++ +AQAAPK LF +Q+ + P GF+VGMKLEAVD+ NPS + Sbjct: 303 LQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLV 362 Query: 364 CVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHF 423 CVA+VTD+VD+RFLVHFDNWD++YDYWC+ SSP+IHPVGWC++ + L P YP+ +F Sbjct: 363 CVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNF 422 Query: 424 SWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVH 483 W+KYLEET + P AFKV+PPH F MKLE VD+RNP IRVA+V D +DHR+K+H Sbjct: 423 CWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIH 482 Query: 484 FDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEAS--------------- 528 FDGW++ YD+WIDAD PDIHP GWCSKTGHPLQPPL P E AS Sbjct: 483 FDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHT 542 Query: 529 -------EHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLN--KDRIFPDRLSGEM 579 H C TPGC G GH + H + CP +E N + K + S Sbjct: 543 RTSKYSFHHRKCPTPGCDGSGHV-TGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARK 601 Query: 580 PPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQ 639 S PR K P+ R +EDF+ T + S Sbjct: 602 KNLSGFSPRKKPRHHGRIGRPPKYR----KIPQEDFQTLTPDVVHQS------------- 644 Query: 640 QAQRRSAVFLSFKSPIP--CLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPG 697 +F+S S P L + WEQ KLLP VAGI AS V+KW+ DEV F+Q+L G Sbjct: 645 -------LFMSALSAHPDRSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFGFVQTLTG 697 Query: 698 CEEHGKVFKDE 708 CE+ ++FKDE Sbjct: 698 CEDQARLFKDE 708 >gi|117938330 l(3)mbt-like isoform II [Homo sapiens] Length = 738 Score = 570 bits (1468), Expect = e-162 Identities = 291/611 (47%), Positives = 370/611 (60%), Gaps = 59/611 (9%) Query: 129 EERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDE---MENKQDVRILRGSQRAR 185 +ER V +N S KP K + E + E ME +++ + G A Sbjct: 126 QERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAMEKQEEGKDPEGQPTAS 185 Query: 186 RKRRGDSAVLKQGLPPKGKK--AWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGM 243 +S P G+K W W SYLEE+KA+ P LF++ Q+ +NKNGFK+GM Sbjct: 186 TP---ESEEWSSSQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGM 242 Query: 244 KLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHK 303 KLEG+DP+H S+Y +LTVAEVCGYR++LHFDGYS+C+DFWVNA++ DIHP GW EKTGHK Sbjct: 243 KLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHK 302 Query: 304 LHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFI 363 L PPKGYKEEEF+W YL++ +AQAAPK LF +Q+ + P GF+VGMKLEAVD+ NPS + Sbjct: 303 LQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLV 362 Query: 364 CVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHF 423 CVA+VTD+VD+RFLVHFDNWD++YDYWC+ SSP+IHPVGWC++ + L P YP+ +F Sbjct: 363 CVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNF 422 Query: 424 SWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVH 483 W+KYLEET + P AFKV+PPH F MKLE VD+RNP IRVA+V D +DHR+K+H Sbjct: 423 CWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIH 482 Query: 484 FDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEAS--------------- 528 FDGW++ YD+WIDAD PDIHP GWCSKTGHPLQPPL P E AS Sbjct: 483 FDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHT 542 Query: 529 -------EHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLN--KDRIFPDRLSGEM 579 H C TPGC G GH + H + CP +E N + K + S Sbjct: 543 RTSKYSFHHRKCPTPGCDGSGHV-TGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARK 601 Query: 580 PPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQ 639 S PR K P+ R +EDF+ T + S Sbjct: 602 KNLSGFSPRKKPRHHGRIGRPPKYR----KIPQEDFQTLTPDVVHQS------------- 644 Query: 640 QAQRRSAVFLSFKSPIP--CLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPG 697 +F+S S P L + WEQ KLLP VAGI AS V+KW+ DEV F+Q+L G Sbjct: 645 -------LFMSALSAHPDRSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFGFVQTLTG 697 Query: 698 CEEHGKVFKDE 708 CE+ ++FKDE Sbjct: 698 CEDQARLFKDE 708 >gi|20149698 l(3)mbt-like 2 [Homo sapiens] Length = 705 Score = 182 bits (463), Expect = 8e-46 Identities = 113/305 (37%), Positives = 162/305 (53%), Gaps = 15/305 (4%) Query: 236 KNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVG 295 K F+ GM+LE VD S + V V G R++L ++ DFW + + IHPVG Sbjct: 320 KYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVG 379 Query: 296 WCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSG-FRVGMKLEA 354 W + GH + + + + + A P LF+ G F GMKLEA Sbjct: 380 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVYTEGGWFEEGMKLEA 436 Query: 355 VDKKNPSFICVATVTD-MVDNRFLVHFDNWD--ESYDYWCEASSPH-IHPVGWCKEHRRT 410 +D N ICVATV ++D ++ D + D++C +S H I P +C+++ Sbjct: 437 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE 496 Query: 411 LITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVK-PPHGFQKKMKLEVVDKRNPMFIRV 469 L P GY + F+W+ YLE+T S AP+R F + P HGF+ MKLE VD P I V Sbjct: 497 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV 555 Query: 470 ATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL-----SPLEL 524 ATV + +HFDGW++ YD W+D +SPDI+PVGWC TG+ LQPP+ +PL+ Sbjct: 556 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKA 615 Query: 525 MEASE 529 EA++ Sbjct: 616 KEATK 620 Score = 125 bits (314), Expect = 1e-28 Identities = 98/338 (28%), Positives = 151/338 (44%), Gaps = 46/338 (13%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEH---QSVYCVLTVAEVC 265 W +L++ A P FK + ++ K GMK+E ++ + VY + +V + Sbjct: 181 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMK-GMKVEVLNSDAVLPSRVYWIASVIQTA 239 Query: 266 GYRIKLHFDGYSD--CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKT 323 GYR+ L ++G+ + +DFW N +D+HP+GWC L PP+ + +W+ YL Sbjct: 240 GYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYL-- 297 Query: 324 CKAQAAPKSLFENQNITVIPS---GFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHF 380 K ++L + +I ++ S FR GM+LE VDK S +A V ++ R + + Sbjct: 298 MKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLY 357 Query: 381 DNWDESYDYWCEASSPHIHPVGWCK---------EHRRTLITPPGYPNVKHFSWDKYLEE 431 ++ D D+WC SP IHPVGW + E R + P + + Y + Sbjct: 358 EDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKI-------YCDA 410 Query: 432 TNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGW-NNC 490 L RA + F++ MKLE +D N I VATV KV DG+ C Sbjct: 411 VPYLFKKVRAVYTE-GGWFEEGMKLEAIDPLNLGNICVATVC-------KVLLDGYLMIC 462 Query: 491 YD----------YWIDADSPDIHPVGWCSKTGHPLQPP 518 D + A S I P +C K L PP Sbjct: 463 VDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPP 500 Score = 102 bits (255), Expect = 1e-21 Identities = 59/150 (39%), Positives = 83/150 (55%), Gaps = 11/150 (7%) Query: 200 PPKGKKA--WCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYC 257 PPKG +A + W +YLE+ K+ A P++LF + +GFKVGMKLE VD + C Sbjct: 499 PPKGYEAQTFNWENYLEKTKSKAAPSRLF----NMDCPNHGFKVGMKLEAVDLMEPRLIC 554 Query: 258 VLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNW 317 V TV V + +HFDG+ YD WV+ ++ DI+PVGWCE TG++L PP + Sbjct: 555 VATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEP----- 609 Query: 318 QTYLKTCKAQAAPKSLFENQNITVIPSGFR 347 T LK +A K F + + P+ R Sbjct: 610 ATPLKAKEATKKKKKQFGKKRKRIPPTKTR 639 Score = 100 bits (249), Expect = 5e-21 Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 23/248 (9%) Query: 291 IHPVGWCEKTGHKLHP----------PKGYKEEE--FNWQTYLKTCKAQAAPKSLFENQN 338 +H W K G LH P G F+W +LK +AAP S F++ Sbjct: 143 LHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVP 202 Query: 339 ITVIPSGFRVGMKLEAV--DKKNPSFI-CVATVTDMVDNRFLVHFDNW--DESYDYWCEA 393 + GMK+E + D PS + +A+V R L+ ++ + D S+D+WC Sbjct: 203 LYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNL 262 Query: 394 SSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEE----TNSLPAPARAFKVKP-PH 448 + +HP+GWC + + L+ PP + K W YL + + +LP V+ + Sbjct: 263 GTVDVHPIGWCAINSKILV-PPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKY 321 Query: 449 GFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWC 508 F++ M+LEVVDK R+A V R+++ ++ ++ D+W SP IHPVGW Sbjct: 322 PFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWS 381 Query: 509 SKTGHPLQ 516 + GH ++ Sbjct: 382 RRVGHGIK 389 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 10/116 (8%) Query: 413 TPPGYPN-VKHFSWDKYLEETNSLPAPARAFKVKPPH----GFQKKMKLEVVDKRNPMFI 467 TP G V F W K+L++ + AP FK P + K MK+EV++ + Sbjct: 168 TPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPS 227 Query: 468 RV---ATVADTDDHRVKVHFDGWNN--CYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 RV A+V T +RV + ++G+ N +D+W + + D+HP+GWC+ L PP Sbjct: 228 RVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP 283 >gi|158508476 mbt domain containing 1 [Homo sapiens] Length = 628 Score = 182 bits (463), Expect = 8e-46 Identities = 111/289 (38%), Positives = 155/289 (53%), Gaps = 18/289 (6%) Query: 239 FKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSD-CYDFWVNADALDIHPVGWC 297 FK M++E VD H V V V G R++L ++ D DFW + + IH +GW Sbjct: 285 FKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWS 344 Query: 298 EKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFEN-QNITVIPSGFRVGMKLEAVD 356 GH+ K+++ ++ T P LF + + F+ GMKLEA+D Sbjct: 345 RSIGHRFKRSDITKKQDGHFDT----------PPHLFAKVKEVDQSGEWFKEGMKLEAID 394 Query: 357 KKNPSFICVATVTDMVDNRFLVHFDNWDESYD---YWC-EASSPHIHPVGWCKEHRRTLI 412 N S ICVAT+ ++ + FL+ + E+ D ++C A+SP I PVG+C+ + L Sbjct: 395 PLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELT 454 Query: 413 TPPGYPNVKHFSWDKYLEETNSLPAPARAF-KVKPPHGFQKKMKLEVVDKRNPMFIRVAT 471 P GY + F W YL ET S+ AP + F K P HGF+ MKLE VD P I VAT Sbjct: 455 PPRGYTKLP-FKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVAT 513 Query: 472 VADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLS 520 V +++HFDGW YD W+D +SPD++PVGWC TG+ LQPP S Sbjct: 514 VTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPAS 562 Score = 110 bits (275), Expect = 5e-24 Identities = 91/331 (27%), Positives = 148/331 (44%), Gaps = 30/331 (9%) Query: 205 KAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQ---SVYCVLTV 261 + + W +Y+ +A P FK H +++E + + V+ + + Sbjct: 139 EGFSWGNYINSNSFIAAPVTCFK-HAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGI 197 Query: 262 AEVCGYRIKLHFDGYSDC--YDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQT 319 ++ GY L ++G+ + DFW N DIHPVGWC +G L PP+ + + NW+ Sbjct: 198 VKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKA 257 Query: 320 YL--KTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRF- 376 +L + A+ P F + + F+ M++E VDK++ VA V ++ R Sbjct: 258 FLVKRLTGAKTLPPD-FSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLR 316 Query: 377 LVHFDNWDESYDYWCEASSPHIHPVGWCKE--HR--RTLITPPGYPNVKHFSWDKYLEET 432 LV+ ++ D + D+WC SP IH +GW + HR R+ IT D + + Sbjct: 317 LVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITK---------KQDGHFDTP 367 Query: 433 NSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADT-DDHRVKVHFDGWNNCY 491 L A + + F++ MKLE +D N I VAT+ D + + DG + Sbjct: 368 PHLFAKVKEVD-QSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDG-SEAA 425 Query: 492 D----YWIDADSPDIHPVGWCSKTGHPLQPP 518 D + A SP I PVG+C L PP Sbjct: 426 DGSDWFCYHATSPSIFPVGFCEINMIELTPP 456 Score = 99.8 bits (247), Expect = 9e-21 Identities = 47/117 (40%), Positives = 69/117 (58%), Gaps = 6/117 (5%) Query: 200 PPKG--KKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYC 257 PP+G K + W YL E ++A P KLF + +GF+VGMKLE VD + C Sbjct: 455 PPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVP----NHGFRVGMKLEAVDLMEPRLIC 510 Query: 258 VLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEE 314 V TV + +++HFDG+ + YD WV+ ++ D++PVGWC+ TG++L PP E Sbjct: 511 VATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRE 567 Score = 54.7 bits (130), Expect = 3e-07 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 9/109 (8%) Query: 419 NVKHFSWDKYLEETNSLPAPARAFKVKPP----HGFQKKMKLEVVDKRNPMFIRV---AT 471 +++ FSW Y+ + + AP FK P + +++EV + + +V A Sbjct: 137 SMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAG 196 Query: 472 VADTDDHRVKVHFDGWNN--CYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 + + + ++G+ N D+W + DIHPVGWC+ +G PL PP Sbjct: 197 IVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPP 245 >gi|5174669 sex comb on midleg-like 2 [Homo sapiens] Length = 700 Score = 171 bits (433), Expect = 2e-42 Identities = 94/243 (38%), Positives = 137/243 (56%), Gaps = 13/243 (5%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YL+E +++ P++ F++ Q P N FKVGMKLE DP + + C+ TV + G R Sbjct: 35 WEEYLKETGSISAPSECFRQSQIPPVND--FKVGMKLEARDPRNATSVCIATVIGITGAR 92 Query: 269 IKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTY-LKTCK-A 326 ++L DG + DFW D+ DI PVG CEK G L PP GY+ +W + LKT + Sbjct: 93 LRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGS 152 Query: 327 QAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDES 386 + A +LF+ + + F+VGMKLEA+DKKNP IC AT+ D+ + + FD W + Sbjct: 153 EMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGA 212 Query: 387 YDYWCEASSPHIHPVGWCKEHRRTLITPPG--YPNVKHFSWDKYLEETNSLPAPARAFKV 444 +DYWC+ S I P GWC+ ++ PPG P VK+ + +T S P+ A + Sbjct: 213 FDYWCKYDSRDIFPAGWCR-LTGDVLQPPGTSVPIVKN------IAKTESSPSEASQHSM 265 Query: 445 KPP 447 + P Sbjct: 266 QSP 268 Score = 160 bits (406), Expect = 3e-39 Identities = 92/241 (38%), Positives = 126/241 (52%), Gaps = 11/241 (4%) Query: 284 VNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIP 343 VN D++D+ EKT + ++F+W+ YLK + +AP F I + Sbjct: 5 VNEDSMDVKKENQ-EKTPQS--STSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPV- 60 Query: 344 SGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGW 403 + F+VGMKLEA D +N + +C+ATV + R + D D D+W SP I PVG Sbjct: 61 NDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGT 120 Query: 404 CKEHRRTLITPPGYPNVKHFSWDKYLEET--NSLPAPARAFKVKPP----HGFQKKMKLE 457 C++ L P GY + SW +L +T S A A FK +PP + F+ MKLE Sbjct: 121 CEKEGDLLQPPLGY-QMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLE 179 Query: 458 VVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQP 517 +DK+NP I AT+ D V + FDGW+ +DYW DS DI P GWC TG LQP Sbjct: 180 AIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQP 239 Query: 518 P 518 P Sbjct: 240 P 240 Score = 87.8 bits (216), Expect = 3e-17 Identities = 44/100 (44%), Positives = 60/100 (60%), Gaps = 3/100 (3%) Query: 423 FSWDKYLEETNSLPAPARAFK---VKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHR 479 F W++YL+ET S+ AP+ F+ + P + F+ MKLE D RN + +ATV R Sbjct: 33 FHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGAR 92 Query: 480 VKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL 519 +++ DG +N D+W DSPDI PVG C K G LQPPL Sbjct: 93 LRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPL 132 Score = 42.4 bits (98), Expect = 0.002 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 681 SKWSTDEVSEFIQSLPG--CEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 S WS DEV +F++ +F+ +IDG+A L+ ++K M +KLGPALK+ Sbjct: 629 STWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKL 687 >gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] Length = 660 Score = 163 bits (413), Expect = 5e-40 Identities = 87/210 (41%), Positives = 119/210 (56%), Gaps = 5/210 (2%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YL+E +V P FK QS+ N FK+ MKLE DP + + C+ TV + G R Sbjct: 30 WDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87 Query: 269 IKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTY-LKTCK-A 326 ++L DG + DFW D+ +I P+G CEK G L PP G++ +W + LKT A Sbjct: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGA 147 Query: 327 QAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDES 386 + AP +F + + + F++GMKLEAVD+KNP FIC AT+ ++ + LV FD W + Sbjct: 148 EMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGA 207 Query: 387 YDYWCEASSPHIHPVGWCKEHRRTLITPPG 416 +DYWC S I PVGWC L PPG Sbjct: 208 FDYWCRFDSRDIFPVGWCSLTGDNL-QPPG 236 Score = 147 bits (372), Expect = 3e-35 Identities = 85/210 (40%), Positives = 112/210 (53%), Gaps = 8/210 (3%) Query: 315 FNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDN 374 F W YLK + AP F+ Q+ T + F++ MKLEA D +N + C+ATV + Sbjct: 28 FTWDKYLKETCSVPAPVHCFK-QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86 Query: 375 RFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEET-- 432 R + D D D+W S I P+G C+++ L P G+ + SW +L +T Sbjct: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGF-RLNASSWPMFLLKTLN 145 Query: 433 NSLPAPARAFKVKPP---HGFQKK-MKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWN 488 + AP R F +PP H F K MKLE VD++NP FI AT+ + V V FDGW Sbjct: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205 Query: 489 NCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 +DYW DS DI PVGWCS TG LQPP Sbjct: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235 Score = 90.1 bits (222), Expect = 7e-18 Identities = 46/101 (45%), Positives = 59/101 (58%), Gaps = 3/101 (2%) Query: 422 HFSWDKYLEETNSLPAPARAFK---VKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDH 478 HF+WDKYL+ET S+PAP FK P + F+ MKLE D RN +ATV Sbjct: 27 HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86 Query: 479 RVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL 519 R+++ DG +N D+W DS +I P+G C K G LQPPL Sbjct: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127 Score = 49.3 bits (116), Expect = 1e-05 Identities = 22/58 (37%), Positives = 37/58 (63%), Gaps = 1/58 (1%) Query: 681 SKWSTDEVSEFIQSL-PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 S W+ ++V +F++ P H +F+ +IDG+A LL+ ++K M +KLGPALK+ Sbjct: 591 SSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648 >gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] Length = 591 Score = 152 bits (384), Expect = 1e-36 Identities = 79/189 (41%), Positives = 109/189 (57%), Gaps = 3/189 (1%) Query: 230 QSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADAL 289 QS+ N FK+ MKLE DP + + C+ TV + G R++L DG + DFW D+ Sbjct: 2 QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSA 61 Query: 290 DIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYL-KTCK-AQAAPKSLFENQNITVIPSGFR 347 +I P+G CEK G L PP G++ +W +L KT A+ AP +F + + + F+ Sbjct: 62 EIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFK 121 Query: 348 VGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEH 407 +GMKLEAVD+KNP FIC AT+ ++ + LV FD W ++DYWC S I PVGWC Sbjct: 122 MGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLT 181 Query: 408 RRTLITPPG 416 L PPG Sbjct: 182 GDNL-QPPG 189 Score = 137 bits (345), Expect = 4e-32 Identities = 77/188 (40%), Positives = 102/188 (54%), Gaps = 7/188 (3%) Query: 337 QNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSP 396 Q+ T + F++ MKLEA D +N + C+ATV + R + D D D+W S Sbjct: 2 QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSA 61 Query: 397 HIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEET--NSLPAPARAFKVKPP---HGFQ 451 I P+G C+++ L P G+ + SW +L +T + AP R F +PP H F Sbjct: 62 EIQPIGNCEKNGGMLQPPLGF-RLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFF 120 Query: 452 KK-MKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSK 510 K MKLE VD++NP FI AT+ + V V FDGW +DYW DS DI PVGWCS Sbjct: 121 KMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSL 180 Query: 511 TGHPLQPP 518 TG LQPP Sbjct: 181 TGDNLQPP 188 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/74 (41%), Positives = 41/74 (55%) Query: 446 PPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPV 505 P + F+ MKLE D RN +ATV R+++ DG +N D+W DS +I P+ Sbjct: 7 PSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPI 66 Query: 506 GWCSKTGHPLQPPL 519 G C K G LQPPL Sbjct: 67 GNCEKNGGMLQPPL 80 Score = 49.3 bits (116), Expect = 1e-05 Identities = 22/58 (37%), Positives = 37/58 (63%), Gaps = 1/58 (1%) Query: 681 SKWSTDEVSEFIQSL-PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 S W+ ++V +F++ P H +F+ +IDG+A LL+ ++K M +KLGPALK+ Sbjct: 522 SSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 579 >gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens] Length = 894 Score = 138 bits (348), Expect = 2e-32 Identities = 106/330 (32%), Positives = 144/330 (43%), Gaps = 23/330 (6%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YLEE A A P FK H N F+ GMKLE + + Y V T+ CG Sbjct: 46 WGEYLEETGASAAPHTSFK-HVEISIQSN-FQPGMKLEVANKNNPDTYWVATIITTCGQL 103 Query: 269 IKLHFDGYSDCY--DFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYL--KTC 324 + L + GY + DFW + D+HPVGWC + L PP KE+ +W +L Sbjct: 104 LLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKVLMPPDAIKEKYTDWTEFLIRDLT 163 Query: 325 KAQAAPKSLFENQNITVIPSG-FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNW 383 ++ AP +L E P VG +E D +NP + +V + V R + + Sbjct: 164 GSRTAPANLLEGPLRGKGPIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGL 223 Query: 384 D--ESYDYWCEASSPHIHPVGWCKEHRRTLITPPG--YPNVKHFSW----DKYLEETNSL 435 + ESYD W + PVGWC+E++ + PP YP W +K L + Sbjct: 224 EDTESYDQWLFYLDYRLRPVGWCQENKYRM-DPPSEIYPLKMASEWKCTLEKSLIDAAKF 282 Query: 436 PAPARAFKVKP---PHGFQKKMKLEVVDKRNPMFIRVATVADT-DDHRVKVHFDGWN--- 488 P P FK H F MKLE V+ P +I A+V ++H +V D Sbjct: 283 PLPMEVFKDHADLRSHFFTVGMKLETVNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEP 342 Query: 489 NCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 + ADS I PV WC K G L PP Sbjct: 343 SKLSMLCHADSLGILPVQWCLKNGVSLTPP 372 Score = 127 bits (318), Expect = 5e-29 Identities = 91/292 (31%), Positives = 139/292 (47%), Gaps = 16/292 (5%) Query: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDC--YDFWVNADALDIHPVGWCE 298 VG +E D ++ Y +++V E G R++L + G D YD W+ + PVGWC+ Sbjct: 188 VGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGLEDTESYDQWLFYLDYRLRPVGWCQ 247 Query: 299 KTGHKLHPPKGYKEEEF--NWQTYLKTCKAQAA----PKSLFENQNITVIPSGFRVGMKL 352 + +++ PP + W+ L+ AA P +F++ + + F VGMKL Sbjct: 248 ENKYRMDPPSEIYPLKMASEWKCTLEKSLIDAAKFPLPMEVFKD-HADLRSHFFTVGMKL 306 Query: 353 EAVDKKNPSFICVATVTDMVDNRFL-VHFDNW---DESYDYWCEASSPHIHPVGWCKEHR 408 E V+ P +I A+VT + +N F V D+ C A S I PV WC ++ Sbjct: 307 ETVNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNG 366 Query: 409 RTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFK-VKPPHGFQKKMKLEVVDKRNPMFI 467 +L P GY + F W Y ++ + AP F+ GF K MKLE V+ RNP + Sbjct: 367 VSLTPPKGYSG-QDFDWADYHKQHGAQEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGEL 425 Query: 468 RVATVADTDDHRVKVHFDGWNNCY-DYWIDADSPDIHPVGWCSKTGHPLQPP 518 VA+V + +H +G + +D +S DI PVGWC +PL P Sbjct: 426 CVASVVSVKGRLMWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSYPLTAP 477 Score = 110 bits (274), Expect = 6e-24 Identities = 70/230 (30%), Positives = 110/230 (47%), Gaps = 13/230 (5%) Query: 311 KEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTD 370 +E FNW YL+ A AAP + F++ I+ I S F+ GMKLE +K NP VAT+ Sbjct: 40 EETGFNWGEYLEETGASAAPHTSFKHVEIS-IQSNFQPGMKLEVANKNNPDTYWVATIIT 98 Query: 371 MVDNRFLVHFDNW--DESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKY 428 L+ + + D D+WC+ +HPVGWC ++ + L+ PP K+ W ++ Sbjct: 99 TCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKVLM-PPDAIKEKYTDWTEF 157 Query: 429 L--EETNSLPAPARAFKVK-----PPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVK 481 L + T S APA + P +E+ D +NP + +V + R++ Sbjct: 158 LIRDLTGSRTAPANLLEGPLRGKGPIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLR 217 Query: 482 VHFDGWNNC--YDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASE 529 + + G + YD W+ + PVGWC + + + PP L ASE Sbjct: 218 LRYVGLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKMASE 267 Score = 98.2 bits (243), Expect = 2e-20 Identities = 73/220 (33%), Positives = 101/220 (45%), Gaps = 14/220 (6%) Query: 204 KKAWCWASYLEEEKAVA----VPAKLFKEHQSFPYNKNGFKVGMKLEGV---DPEHQSVY 256 K A W LE+ A +P ++FK+H + F VGMKLE V +P + S Sbjct: 263 KMASEWKCTLEKSLIDAAKFPLPMEVFKDHADL--RSHFFTVGMKLETVNMCEPFYISPA 320 Query: 257 CVLTVAEVCGYRIKLH-FDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEF 315 V V +++ + +AD+L I PV WC K G L PPKGY ++F Sbjct: 321 SVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVSLTPPKGYSGQDF 380 Query: 316 NWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNR 375 +W Y K AQ AP F N T GF MKLEAV+ +NP +CVA+V + Sbjct: 381 DWADYHKQHGAQEAPPFCFRN---TSFSRGFTKNMKLEAVNPRNPGELCVASVVSVKGRL 437 Query: 376 FLVHFDNWDESY-DYWCEASSPHIHPVGWCKEHRRTLITP 414 +H + + + S I PVGWC+ + L P Sbjct: 438 MWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSYPLTAP 477 Score = 55.8 bits (133), Expect = 1e-07 Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 30/178 (16%) Query: 597 SSSSPEIRDQHADDVKEDF-EERTESEMRTSHEARGAREEPTVQQAQRRSAVFLSFKSPI 655 + S E ++ AD + +D E T SE+R + E P+ + RR+ S P+ Sbjct: 713 AGSGEESEEEDADAMDDDTASEETGSELRDDQTDTSSAEVPSARP--RRAVTLRSGSEPV 770 Query: 656 PCLPLRWEQQSKLLPTVAG--------------------------IPASKVSKWSTDEVS 689 P ++ + P + + S +W+ +V Sbjct: 771 RRPPPERTRRGRGAPAASSAEEGEKCPPTKPEGTEDTKQEEEERLVLESNPLEWTVTDVV 830 Query: 690 EFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAA 747 FI+ L C K+F+++ IDG+A LL+T + + M +KLGPA+K+ + I K A Sbjct: 831 RFIK-LTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVA 887 >gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens] Length = 866 Score = 138 bits (347), Expect = 2e-32 Identities = 96/278 (34%), Positives = 142/278 (51%), Gaps = 22/278 (7%) Query: 258 VLTVAEVCGYRIKLHFDGY--SDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYK--EE 313 ++TV E G R+KL ++G SD Y+ W+ +H VGW + G++L PP + + Sbjct: 181 IVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKN 240 Query: 314 EFNWQTYLKTCKAQAA---PKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTD 370 E WQ L K + P LF+++ + I + F V MKLEAVD +P I ATV Sbjct: 241 EAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT-FSVNMKLEAVDPWSPFGISPATVVK 299 Query: 371 MVDNR-FLVHFDNW-DESY---DYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSW 425 + D + FLV D+ E++ + C A SP I PV W ++ + PPGYP+ + F W Sbjct: 300 VFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPS-QDFDW 358 Query: 426 DKYLEETNSLPAPARAFKVKPP----HGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVK 481 YL++ + AP R F PP H F++ MKLE V+ P + VAT+ + Sbjct: 359 ADYLKQCGAEAAPQRCF---PPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLW 415 Query: 482 VHFDGWNNCY-DYWIDADSPDIHPVGWCSKTGHPLQPP 518 + +G + + +S DI P+GWC GHPL P Sbjct: 416 LQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 130 bits (328), Expect = 3e-30 Identities = 101/334 (30%), Positives = 145/334 (43%), Gaps = 31/334 (9%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YLEE + AVP FK + +NGF GMKLE Y V TV C Sbjct: 22 WEDYLEETGSTAVPYGSFKHVDT--RLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQL 79 Query: 269 IKLHFDGYSDCY--DFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLK--TC 324 + L +DGY + DFW + D++P+GWCE+ L P+G +++ +W +L+ Sbjct: 80 LLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLI 139 Query: 325 KAQAAPKSLFENQNITVIPSG-FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNW 383 A + P L E P G +LE ++ + TV + + R + ++ Sbjct: 140 GACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199 Query: 384 DES--YDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKH-FSWDKYL---EETNSLPA 437 + S Y++W P +H VGW + L P ++K+ W + L +E P Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPL 259 Query: 438 PARAFKVKPP---HGFQKKMKLEVVDKRNPMFIRVATV----------ADTDDHRVKVHF 484 P+ FK K H F MKLE VD +P I ATV + DD R + H Sbjct: 260 PSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHA 319 Query: 485 DGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 C+ ADSP I PV W K G + PP Sbjct: 320 RRSFVCH-----ADSPGIFPVQWSLKNGLHISPP 348 Score = 108 bits (269), Expect = 2e-23 Identities = 66/232 (28%), Positives = 116/232 (50%), Gaps = 13/232 (5%) Query: 309 GYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATV 368 G +E E +W+ YL+ + A P F++ + T + +GF GMKLE + +P VATV Sbjct: 14 GMEEVELSWEDYLEETGSTAVPYGSFKHVD-TRLQNGFAPGMKLEVAVRTDPETYWVATV 72 Query: 369 TDMVDNRFLVHFDNW--DESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWD 426 + L+ +D + D D+WC+ ++P+GWC+++++TL P G + K WD Sbjct: 73 ITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRD-KVSDWD 131 Query: 427 KYLEETN----SLPAP---ARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHR 479 ++L +T S P P P +LE ++ + + TV + R Sbjct: 132 EFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGR 191 Query: 480 VKVHFDGWNNC--YDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASE 529 +K+ ++G + Y++W+ P +H VGW ++ G+ LQPP + L +E Sbjct: 192 LKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAE 243 Score = 92.4 bits (228), Expect = 1e-18 Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 11/208 (5%) Query: 213 LEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKL- 271 ++EE+ +P+ LFK+ Q + F V MKLE VDP TV +V + L Sbjct: 251 VKEEEEEPLPSYLFKDKQVIGIHT--FSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLV 308 Query: 272 HFDGYSD----CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQ 327 D F +AD+ I PV W K G + PP GY ++F+W YLK C A+ Sbjct: 309 EMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAE 368 Query: 328 AAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESY 387 AAP+ F + F+ MKLEAV+ P +CVAT+T + + + + + Sbjct: 369 AAPQRCFPP---LISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPI 425 Query: 388 -DYWCEASSPHIHPVGWCKEHRRTLITP 414 + S I P+GWC+ + L TP Sbjct: 426 PECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 64.7 bits (156), Expect = 3e-10 Identities = 81/312 (25%), Positives = 129/312 (41%), Gaps = 62/312 (19%) Query: 43 LEVITDENEMENVKKATATTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQY- 101 L++I + +E + +TW+V + + RLK ++ EGL+ +N + Sbjct: 159 LDLIAPGSRLECQAFQDSLSTWIVTVVENIGG-------RLK--LRYEGLESSDNYEHWL 209 Query: 102 GNVDECLSGGNYCSQ--------NCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLS 153 +D L + +Q + RH+K++ + +E + EEE+P S K K Sbjct: 210 YYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQV 269 Query: 154 LKADTKEDGEERD-------------------DEMENKQDVRILRGSQRARRKR--RGDS 192 + T + + DE ++ LR ARR DS Sbjct: 270 IGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADS 329 Query: 193 A-------VLKQGL---PPKG--KKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK 240 LK GL PP G + + WA YL++ A A P + F S ++ FK Sbjct: 330 PGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLIS----EHEFK 385 Query: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYS----DCYDFWVNADALDIHPVGW 296 MKLE V+P CV T+ V G + L +G +C V+ +++DI P+GW Sbjct: 386 ENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECI---VSVESMDIFPLGW 442 Query: 297 CEKTGHKLHPPK 308 CE GH L P+ Sbjct: 443 CETNGHPLSTPR 454 Score = 57.4 bits (137), Expect = 5e-08 Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 18/178 (10%) Query: 580 PPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE---- 635 P SP + D + + + + +++ +E +E + S + + E Sbjct: 690 PAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTS 749 Query: 636 -PTVQQAQRRSAVFLSF-----KSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVS 689 P +Q ++R SF K P P +R E +L S KWS +V Sbjct: 750 LPPDRQRRKRELRTFSFSDDENKPPSP-KEIRIEVAERLHLD------SNPLKWSVADVV 802 Query: 690 EFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAA 747 FI+S C ++F D++IDG+A LL+T + + M +KLGPA+K+ + I K A Sbjct: 803 RFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFA 859 >gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens] Length = 866 Score = 138 bits (347), Expect = 2e-32 Identities = 96/278 (34%), Positives = 142/278 (51%), Gaps = 22/278 (7%) Query: 258 VLTVAEVCGYRIKLHFDGY--SDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYK--EE 313 ++TV E G R+KL ++G SD Y+ W+ +H VGW + G++L PP + + Sbjct: 181 IVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKN 240 Query: 314 EFNWQTYLKTCKAQAA---PKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTD 370 E WQ L K + P LF+++ + I + F V MKLEAVD +P I ATV Sbjct: 241 EAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT-FSVNMKLEAVDPWSPFGISPATVVK 299 Query: 371 MVDNR-FLVHFDNW-DESY---DYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSW 425 + D + FLV D+ E++ + C A SP I PV W ++ + PPGYP+ + F W Sbjct: 300 VFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPS-QDFDW 358 Query: 426 DKYLEETNSLPAPARAFKVKPP----HGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVK 481 YL++ + AP R F PP H F++ MKLE V+ P + VAT+ + Sbjct: 359 ADYLKQCGAEAAPQRCF---PPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLW 415 Query: 482 VHFDGWNNCY-DYWIDADSPDIHPVGWCSKTGHPLQPP 518 + +G + + +S DI P+GWC GHPL P Sbjct: 416 LQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 130 bits (328), Expect = 3e-30 Identities = 101/334 (30%), Positives = 145/334 (43%), Gaps = 31/334 (9%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YLEE + AVP FK + +NGF GMKLE Y V TV C Sbjct: 22 WEDYLEETGSTAVPYGSFKHVDT--RLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQL 79 Query: 269 IKLHFDGYSDCY--DFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLK--TC 324 + L +DGY + DFW + D++P+GWCE+ L P+G +++ +W +L+ Sbjct: 80 LLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLI 139 Query: 325 KAQAAPKSLFENQNITVIPSG-FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNW 383 A + P L E P G +LE ++ + TV + + R + ++ Sbjct: 140 GACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199 Query: 384 DES--YDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKH-FSWDKYL---EETNSLPA 437 + S Y++W P +H VGW + L P ++K+ W + L +E P Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPL 259 Query: 438 PARAFKVKPP---HGFQKKMKLEVVDKRNPMFIRVATV----------ADTDDHRVKVHF 484 P+ FK K H F MKLE VD +P I ATV + DD R + H Sbjct: 260 PSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHA 319 Query: 485 DGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 C+ ADSP I PV W K G + PP Sbjct: 320 RRSFVCH-----ADSPGIFPVQWSLKNGLHISPP 348 Score = 108 bits (269), Expect = 2e-23 Identities = 66/232 (28%), Positives = 116/232 (50%), Gaps = 13/232 (5%) Query: 309 GYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATV 368 G +E E +W+ YL+ + A P F++ + T + +GF GMKLE + +P VATV Sbjct: 14 GMEEVELSWEDYLEETGSTAVPYGSFKHVD-TRLQNGFAPGMKLEVAVRTDPETYWVATV 72 Query: 369 TDMVDNRFLVHFDNW--DESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWD 426 + L+ +D + D D+WC+ ++P+GWC+++++TL P G + K WD Sbjct: 73 ITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRD-KVSDWD 131 Query: 427 KYLEETN----SLPAP---ARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHR 479 ++L +T S P P P +LE ++ + + TV + R Sbjct: 132 EFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGR 191 Query: 480 VKVHFDGWNNC--YDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASE 529 +K+ ++G + Y++W+ P +H VGW ++ G+ LQPP + L +E Sbjct: 192 LKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAE 243 Score = 92.4 bits (228), Expect = 1e-18 Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 11/208 (5%) Query: 213 LEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKL- 271 ++EE+ +P+ LFK+ Q + F V MKLE VDP TV +V + L Sbjct: 251 VKEEEEEPLPSYLFKDKQVIGIHT--FSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLV 308 Query: 272 HFDGYSD----CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQ 327 D F +AD+ I PV W K G + PP GY ++F+W YLK C A+ Sbjct: 309 EMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAE 368 Query: 328 AAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESY 387 AAP+ F + F+ MKLEAV+ P +CVAT+T + + + + + Sbjct: 369 AAPQRCFPP---LISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPI 425 Query: 388 -DYWCEASSPHIHPVGWCKEHRRTLITP 414 + S I P+GWC+ + L TP Sbjct: 426 PECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 64.7 bits (156), Expect = 3e-10 Identities = 81/312 (25%), Positives = 129/312 (41%), Gaps = 62/312 (19%) Query: 43 LEVITDENEMENVKKATATTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQY- 101 L++I + +E + +TW+V + + RLK ++ EGL+ +N + Sbjct: 159 LDLIAPGSRLECQAFQDSLSTWIVTVVENIGG-------RLK--LRYEGLESSDNYEHWL 209 Query: 102 GNVDECLSGGNYCSQ--------NCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLS 153 +D L + +Q + RH+K++ + +E + EEE+P S K K Sbjct: 210 YYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQV 269 Query: 154 LKADTKEDGEERD-------------------DEMENKQDVRILRGSQRARRKR--RGDS 192 + T + + DE ++ LR ARR DS Sbjct: 270 IGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADS 329 Query: 193 A-------VLKQGL---PPKG--KKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK 240 LK GL PP G + + WA YL++ A A P + F S ++ FK Sbjct: 330 PGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLIS----EHEFK 385 Query: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYS----DCYDFWVNADALDIHPVGW 296 MKLE V+P CV T+ V G + L +G +C V+ +++DI P+GW Sbjct: 386 ENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECI---VSVESMDIFPLGW 442 Query: 297 CEKTGHKLHPPK 308 CE GH L P+ Sbjct: 443 CETNGHPLSTPR 454 Score = 57.4 bits (137), Expect = 5e-08 Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 18/178 (10%) Query: 580 PPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE---- 635 P SP + D + + + + +++ +E +E + S + + E Sbjct: 690 PAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTS 749 Query: 636 -PTVQQAQRRSAVFLSF-----KSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVS 689 P +Q ++R SF K P P +R E +L S KWS +V Sbjct: 750 LPPDRQRRKRELRTFSFSDDENKPPSP-KEIRIEVAERLHLD------SNPLKWSVADVV 802 Query: 690 EFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAA 747 FI+S C ++F D++IDG+A LL+T + + M +KLGPA+K+ + I K A Sbjct: 803 RFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFA 859 >gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens] Length = 866 Score = 138 bits (347), Expect = 2e-32 Identities = 96/278 (34%), Positives = 142/278 (51%), Gaps = 22/278 (7%) Query: 258 VLTVAEVCGYRIKLHFDGY--SDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYK--EE 313 ++TV E G R+KL ++G SD Y+ W+ +H VGW + G++L PP + + Sbjct: 181 IVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKN 240 Query: 314 EFNWQTYLKTCKAQAA---PKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTD 370 E WQ L K + P LF+++ + I + F V MKLEAVD +P I ATV Sbjct: 241 EAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHT-FSVNMKLEAVDPWSPFGISPATVVK 299 Query: 371 MVDNR-FLVHFDNW-DESY---DYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSW 425 + D + FLV D+ E++ + C A SP I PV W ++ + PPGYP+ + F W Sbjct: 300 VFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPS-QDFDW 358 Query: 426 DKYLEETNSLPAPARAFKVKPP----HGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVK 481 YL++ + AP R F PP H F++ MKLE V+ P + VAT+ + Sbjct: 359 ADYLKQCGAEAAPQRCF---PPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLW 415 Query: 482 VHFDGWNNCY-DYWIDADSPDIHPVGWCSKTGHPLQPP 518 + +G + + +S DI P+GWC GHPL P Sbjct: 416 LQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 130 bits (328), Expect = 3e-30 Identities = 101/334 (30%), Positives = 145/334 (43%), Gaps = 31/334 (9%) Query: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268 W YLEE + AVP FK + +NGF GMKLE Y V TV C Sbjct: 22 WEDYLEETGSTAVPYGSFKHVDT--RLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQL 79 Query: 269 IKLHFDGYSDCY--DFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLK--TC 324 + L +DGY + DFW + D++P+GWCE+ L P+G +++ +W +L+ Sbjct: 80 LLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLI 139 Query: 325 KAQAAPKSLFENQNITVIPSG-FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNW 383 A + P L E P G +LE ++ + TV + + R + ++ Sbjct: 140 GACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199 Query: 384 DES--YDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKH-FSWDKYL---EETNSLPA 437 + S Y++W P +H VGW + L P ++K+ W + L +E P Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPL 259 Query: 438 PARAFKVKPP---HGFQKKMKLEVVDKRNPMFIRVATV----------ADTDDHRVKVHF 484 P+ FK K H F MKLE VD +P I ATV + DD R + H Sbjct: 260 PSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHA 319 Query: 485 DGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518 C+ ADSP I PV W K G + PP Sbjct: 320 RRSFVCH-----ADSPGIFPVQWSLKNGLHISPP 348 Score = 108 bits (269), Expect = 2e-23 Identities = 66/232 (28%), Positives = 116/232 (50%), Gaps = 13/232 (5%) Query: 309 GYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATV 368 G +E E +W+ YL+ + A P F++ + T + +GF GMKLE + +P VATV Sbjct: 14 GMEEVELSWEDYLEETGSTAVPYGSFKHVD-TRLQNGFAPGMKLEVAVRTDPETYWVATV 72 Query: 369 TDMVDNRFLVHFDNW--DESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWD 426 + L+ +D + D D+WC+ ++P+GWC+++++TL P G + K WD Sbjct: 73 ITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRD-KVSDWD 131 Query: 427 KYLEETN----SLPAP---ARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHR 479 ++L +T S P P P +LE ++ + + TV + R Sbjct: 132 EFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGR 191 Query: 480 VKVHFDGWNNC--YDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASE 529 +K+ ++G + Y++W+ P +H VGW ++ G+ LQPP + L +E Sbjct: 192 LKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAE 243 Score = 92.4 bits (228), Expect = 1e-18 Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 11/208 (5%) Query: 213 LEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKL- 271 ++EE+ +P+ LFK+ Q + F V MKLE VDP TV +V + L Sbjct: 251 VKEEEEEPLPSYLFKDKQVIGIHT--FSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLV 308 Query: 272 HFDGYSD----CYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQ 327 D F +AD+ I PV W K G + PP GY ++F+W YLK C A+ Sbjct: 309 EMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAE 368 Query: 328 AAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESY 387 AAP+ F + F+ MKLEAV+ P +CVAT+T + + + + + Sbjct: 369 AAPQRCFPP---LISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPI 425 Query: 388 -DYWCEASSPHIHPVGWCKEHRRTLITP 414 + S I P+GWC+ + L TP Sbjct: 426 PECIVSVESMDIFPLGWCETNGHPLSTP 453 Score = 64.7 bits (156), Expect = 3e-10 Identities = 81/312 (25%), Positives = 129/312 (41%), Gaps = 62/312 (19%) Query: 43 LEVITDENEMENVKKATATTTWMVPTAQEVFSEKTGMPFRLKDPVKVEGLQFCENCCQY- 101 L++I + +E + +TW+V + + RLK ++ EGL+ +N + Sbjct: 159 LDLIAPGSRLECQAFQDSLSTWIVTVVENIGG-------RLK--LRYEGLESSDNYEHWL 209 Query: 102 GNVDECLSGGNYCSQ--------NCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLS 153 +D L + +Q + RH+K++ + +E + EEE+P S K K Sbjct: 210 YYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQV 269 Query: 154 LKADTKEDGEERD-------------------DEMENKQDVRILRGSQRARRKR--RGDS 192 + T + + DE ++ LR ARR DS Sbjct: 270 IGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADS 329 Query: 193 A-------VLKQGL---PPKG--KKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFK 240 LK GL PP G + + WA YL++ A A P + F S ++ FK Sbjct: 330 PGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLIS----EHEFK 385 Query: 241 VGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYS----DCYDFWVNADALDIHPVGW 296 MKLE V+P CV T+ V G + L +G +C V+ +++DI P+GW Sbjct: 386 ENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECI---VSVESMDIFPLGW 442 Query: 297 CEKTGHKLHPPK 308 CE GH L P+ Sbjct: 443 CETNGHPLSTPR 454 Score = 57.4 bits (137), Expect = 5e-08 Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 18/178 (10%) Query: 580 PPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE---- 635 P SP + D + + + + +++ +E +E + S + + E Sbjct: 690 PAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTS 749 Query: 636 -PTVQQAQRRSAVFLSF-----KSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVS 689 P +Q ++R SF K P P +R E +L S KWS +V Sbjct: 750 LPPDRQRRKRELRTFSFSDDENKPPSP-KEIRIEVAERLHLD------SNPLKWSVADVV 802 Query: 690 EFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAA 747 FI+S C ++F D++IDG+A LL+T + + M +KLGPA+K+ + I K A Sbjct: 803 RFIRSTD-CAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFA 859 >gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens] Length = 323 Score = 73.9 bits (180), Expect = 5e-13 Identities = 33/68 (48%), Positives = 51/68 (75%) Query: 678 SKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 S+ +KW+ ++V EFI+SLPGC+E + F+ ++IDG+A LL+ + ++ M+IKLGPALKI Sbjct: 254 SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 313 Query: 738 FNSILMFK 745 + I M K Sbjct: 314 YARISMLK 321 >gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] Length = 858 Score = 73.9 bits (180), Expect = 5e-13 Identities = 33/68 (48%), Positives = 51/68 (75%) Query: 678 SKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 S+ +KW+ ++V EFI+SLPGC+E + F+ ++IDG+A LL+ + ++ M+IKLGPALKI Sbjct: 789 SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848 Query: 738 FNSILMFK 745 + I M K Sbjct: 849 YARISMLK 856 >gi|62953127 polyhomeotic 1-like [Homo sapiens] Length = 1004 Score = 69.7 bits (169), Expect = 9e-12 Identities = 33/69 (47%), Positives = 48/69 (69%) Query: 677 ASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALK 736 +S S+WS +EV EFI SL GC+E + F+ ++IDG+A LL+ + ++ M+IKLGPALK Sbjct: 934 SSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALK 993 Query: 737 IFNSILMFK 745 I I + K Sbjct: 994 ICAKINVLK 1002 >gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens] Length = 446 Score = 69.7 bits (169), Expect = 9e-12 Identities = 30/62 (48%), Positives = 43/62 (69%) Query: 680 VSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFN 739 + KW+ D+V FI+SLPGC ++ +VFKD IDGE L+T+ + M +KLGPALKI + Sbjct: 324 IQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGETLPLLTEEHLRGTMGLKLGPALKIQS 383 Query: 740 SI 741 + Sbjct: 384 QV 385 >gi|148612879 polyhomeotic like 3 [Homo sapiens] Length = 995 Score = 65.1 bits (157), Expect = 2e-10 Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 4/74 (5%) Query: 664 QQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDI 723 + S LLP P S W+ D+V FI SLPGC++ F+ ++IDG+A LL+ + + Sbjct: 916 ENSDLLPVAQTEP----SIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHL 971 Query: 724 VKIMSIKLGPALKI 737 + M+IKLGPALKI Sbjct: 972 MSAMNIKLGPALKI 985 Score = 30.4 bits (67), Expect = 6.3 Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 15/117 (12%) Query: 95 CENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKE----ERDVEEDNEEEDPKCSRKKKP 150 CE C + G +E L +C+ +CA+ K+ + + DN+ + R P Sbjct: 797 CEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGP 856 Query: 151 KLSLK-----------ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLK 196 + + +ED +D + + R+ R S+R R + D + K Sbjct: 857 DGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRK 913 >gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] Length = 681 Score = 62.8 bits (151), Expect = 1e-09 Identities = 27/58 (46%), Positives = 41/58 (70%) Query: 680 VSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737 V+KW+ D+V F+ L GC E+ +VF+++ IDGE L+T+ ++ M +KLGPALKI Sbjct: 540 VTKWTVDDVCSFVGGLSGCGEYTRVFREQGIDGETLPLLTEEHLLTNMGLKLGPALKI 597 >gi|197927257 sterile alpha motif domain containing 13 isoform 2 [Homo sapiens] Length = 102 Score = 51.6 bits (122), Expect = 3e-06 Identities = 22/56 (39%), Positives = 40/56 (71%), Gaps = 1/56 (1%) Query: 683 WSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIF 738 W+ +V + +++ G EE F++++IDG++ LLMT+ D++ + +KLGPALKI+ Sbjct: 31 WAVMDVVNYFRTV-GFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALKIY 85 >gi|197927255 sterile alpha motif domain containing 13 isoform 2 [Homo sapiens] Length = 102 Score = 51.6 bits (122), Expect = 3e-06 Identities = 22/56 (39%), Positives = 40/56 (71%), Gaps = 1/56 (1%) Query: 683 WSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIF 738 W+ +V + +++ G EE F++++IDG++ LLMT+ D++ + +KLGPALKI+ Sbjct: 31 WAVMDVVNYFRTV-GFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALKIY 85 >gi|58293756 sterile alpha motif domain containing 13 isoform 1 [Homo sapiens] Length = 116 Score = 51.6 bits (122), Expect = 3e-06 Identities = 22/56 (39%), Positives = 40/56 (71%), Gaps = 1/56 (1%) Query: 683 WSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIF 738 W+ +V + +++ G EE F++++IDG++ LLMT+ D++ + +KLGPALKI+ Sbjct: 45 WAVMDVVNYFRTV-GFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALKIY 99 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 50.1 bits (118), Expect = 8e-06 Identities = 23/57 (40%), Positives = 39/57 (68%), Gaps = 1/57 (1%) Query: 682 KWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIF 738 +W+ +V E+ G E F++++IDG++ LLM +TD++ +SI+LGPALKI+ Sbjct: 461 EWTVMDVVEYFTEA-GFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIY 516 >gi|158508495 sex comb on midleg-like 4 [Homo sapiens] Length = 414 Score = 43.9 bits (102), Expect = 6e-04 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 681 SKWSTDEVSEFIQSLP--GCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIF 738 S W+ ++V F++ H ++F+ +IDG A LL+ ++K + +KLGPALK+ Sbjct: 344 SAWTVEDVVWFVKDADPQALGPHVELFRKHEIDGNALLLLKSDMVMKYLGLKLGPALKLC 403 Query: 739 NSILMFKAAE 748 I K A+ Sbjct: 404 YHIDKLKQAK 413 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 40.4 bits (93), Expect = 0.006 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 6/105 (5%) Query: 533 CSTPGCKGIGHF--KRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNK 590 C TPGC G GH K ARH S CP ++ +D+ P + + P + + Sbjct: 31 CPTPGCDGSGHVSGKYARH---RSVYGCPLAKKRKTQDK-QPQEPAPKRKPFAVKADSSS 86 Query: 591 RTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE 635 + ++S + ++ ++ D+ +E E+ E + G REE Sbjct: 87 VDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE 131 Score = 34.7 bits (78), Expect = 0.34 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 10/62 (16%) Query: 123 KDKDQKEERDVEE---------DNEEEDPKCSRKKKPKLSLK-ADTKEDGEERDDEMENK 172 +D D+KEE + EE D +EED + R+++ ++ + D EDGE+ +DE E + Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156 Query: 173 QD 174 ++ Sbjct: 157 EE 158 Score = 32.0 bits (71), Expect = 2.2 Identities = 14/62 (22%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSR-KKKPKLSLKADTKEDGEERDDEMENKQDVRILRGS 181 ++ D++EE ++EE++E++D + + + + + +E+ EE +D N + RI++ + Sbjct: 125 EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDT 184 Query: 182 QR 183 ++ Sbjct: 185 EK 186 Score = 31.6 bits (70), Expect = 2.8 Identities = 16/70 (22%), Positives = 37/70 (52%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRGSQ 182 ++++++EE + EE+NE+ C + + + K D D + DE+ K + + + ++ Sbjct: 154 EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAE 213 Query: 183 RARRKRRGDS 192 A + R +S Sbjct: 214 DAAYRARTES 223 Score = 31.6 bits (70), Expect = 2.8 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 11/46 (23%) Query: 533 CSTPGCKGIGHFKRARHLGPH--SAANCPYSEINLNKDRIFPDRLS 576 C TPGC G GH L PH S + CP+ KDR+ P+ L+ Sbjct: 504 CPTPGCDGTGH---VTGLYPHHRSLSGCPH------KDRVPPEILA 540 Score = 30.4 bits (67), Expect = 6.3 Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 15/117 (12%) Query: 528 SEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFP 587 +E C TPGC G GH L S + CP + + K ++ +++ AS Sbjct: 1000 TEGMSCPTPGCDGSGHVS-GSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIE 1058 Query: 588 RNKR--------TDANESSSSPEIRDQHADDVKEDFEERT-ESEMRTSHEARGAREE 635 ++ + NES+S E AD +K + T ES ++T E E+ Sbjct: 1059 NDEEIKQLDEEIKELNESNSQME-----ADMIKLRTQITTMESNLKTIEEENKVIEQ 1110 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 40.0 bits (92), Expect = 0.008 Identities = 24/82 (29%), Positives = 40/82 (48%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRGSQ 182 K K KE +E EEE + ++KK K + + +E+ EE + E E K++ R + + Sbjct: 42 KKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101 Query: 183 RARRKRRGDSAVLKQGLPPKGK 204 + RRK + K+ K K Sbjct: 102 KRRRKEEEEEKKKKRRRKTKKK 123 Score = 39.3 bits (90), Expect = 0.014 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 123 KDKDQKE---ERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILR 179 K+K++K+ E + ++ EEE+ K RK+K K + + +E+ EE ++E E ++ R Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE-EEEREEEEEEEEEEKEEEEKEEGRR 96 Query: 180 GSQRARRKRRGDSAVLKQGLPPKGKK 205 ++ +R+R+ + K+ K KK Sbjct: 97 RKKKKKRRRKEEEEEKKKKRRRKTKK 122 Score = 35.0 bits (79), Expect = 0.26 Identities = 18/65 (27%), Positives = 34/65 (52%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRGSQ 182 K K+ +E + EE EEE+ + RK+K K K K+ + ++ + K++ R + Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 Query: 183 RARRK 187 R ++K Sbjct: 66 RKKKK 70 Score = 32.3 bits (72), Expect = 1.7 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 120 RHIKDKDQKEERDVEEDNEEEDPKCSRK---KKPKLSLKADTKEDGEERDDEMENK 172 R K K ++EER+ EE+ EEE+ + K ++ K K KE+ EE+ + K Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 Score = 31.6 bits (70), Expect = 2.8 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 10/70 (14%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKPK---LSLKADTKEDGEERDDEMENKQDVRILR 179 K+ ++ EE + E+ EE++ K K+K K K TKE + ++ E E K+ Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK------ 61 Query: 180 GSQRARRKRR 189 +R R+K++ Sbjct: 62 -RKRKRKKKK 70 >gi|18034775 PHD finger protein 20 [Homo sapiens] Length = 1012 Score = 39.7 bits (91), Expect = 0.010 Identities = 18/56 (32%), Positives = 28/56 (50%) Query: 346 FRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPV 401 F VG +LEA D+ + D + + L+HF W+ YD W SP++ P+ Sbjct: 13 FEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCWDSPYLRPL 68 Score = 36.2 bits (82), Expect = 0.12 Identities = 17/56 (30%), Positives = 28/56 (50%) Query: 450 FQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPV 505 F+ +LE D+ + D ++ +V +HF WN+ YD W DSP + P+ Sbjct: 13 FEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCWDSPYLRPL 68 >gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo sapiens] Length = 1632 Score = 38.9 bits (89), Expect = 0.018 Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 4/55 (7%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKP----KLSLKADTKEDGEERDDEMENKQ 173 +++D+KEE+ + +E PK K++P + ++AD EDG+E+D++ Q Sbjct: 251 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 305 Score = 30.4 bits (67), Expect = 6.3 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 35/164 (21%) Query: 122 IKDKDQKEER-----DVEEDNEEEDPKCSRKKKPKLSLKADTKED---------GEERDD 167 +K++ +E R D +ED +E+D K R + L+ K +E +E+D+ Sbjct: 274 LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 333 Query: 168 EMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE---------EKA 218 + + ++ + ++ R + + + PPK + YL++ A Sbjct: 334 DEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQC---GQYLDDPDLKYGQHPPDA 390 Query: 219 VAVPAKLFKEHQS-FPYNKNGFKVGMKLEGVDPEHQ----SVYC 257 V P L E S F N++GF+ L P+H+ SVYC Sbjct: 391 VDEPQMLTNEKLSIFDANESGFESYEAL----PQHKLTCFSVYC 430 >gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo sapiens] Length = 1616 Score = 38.9 bits (89), Expect = 0.018 Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 4/55 (7%) Query: 123 KDKDQKEERDVEEDNEEEDPKCSRKKKP----KLSLKADTKEDGEERDDEMENKQ 173 +++D+KEE+ + +E PK K++P + ++AD EDG+E+D++ Q Sbjct: 235 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 289 Score = 30.4 bits (67), Expect = 6.3 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 35/164 (21%) Query: 122 IKDKDQKEER-----DVEEDNEEEDPKCSRKKKPKLSLKADTKED---------GEERDD 167 +K++ +E R D +ED +E+D K R + L+ K +E +E+D+ Sbjct: 258 LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317 Query: 168 EMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE---------EKA 218 + + ++ + ++ R + + + PPK + YL++ A Sbjct: 318 DEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQC---GQYLDDPDLKYGQHPPDA 374 Query: 219 VAVPAKLFKEHQS-FPYNKNGFKVGMKLEGVDPEHQ----SVYC 257 V P L E S F N++GF+ L P+H+ SVYC Sbjct: 375 VDEPQMLTNEKLSIFDANESGFESYEAL----PQHKLTCFSVYC 414 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,233,942 Number of Sequences: 37866 Number of extensions: 1721975 Number of successful extensions: 11649 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 141 Number of HSP's successfully gapped in prelim test: 146 Number of HSP's that attempted gapping in prelim test: 8885 Number of HSP's gapped (non-prelim): 2017 length of query: 755 length of database: 18,247,518 effective HSP length: 110 effective length of query: 645 effective length of database: 14,082,258 effective search space: 9083056410 effective search space used: 9083056410 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.