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Search of human proteins with 55743159
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55743159 WD repeat domain 33 isoform 3 [Homo sapiens]
(257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55743159 WD repeat domain 33 isoform 3 [Homo sapiens] 549 e-156
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 510 e-145
gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens] 441 e-124
gi|13376840 WD repeat domain 61 [Homo sapiens] 63 3e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 55 6e-08
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 55 6e-08
gi|21071067 TBP-associated factor 5 [Homo sapiens] 54 1e-07
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 53 3e-07
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 53 3e-07
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 53 3e-07
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 53 3e-07
gi|26665869 WD repeat domain 51B [Homo sapiens] 53 3e-07
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 52 4e-07
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 52 4e-07
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 52 4e-07
gi|113865883 WD repeat domain 38 [Homo sapiens] 52 4e-07
gi|4757988 WD repeat domain 39 [Homo sapiens] 52 7e-07
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 52 7e-07
gi|19913367 transducin beta-like 1Y [Homo sapiens] 51 1e-06
gi|19913365 transducin beta-like 1Y [Homo sapiens] 51 1e-06
gi|15150805 transducin beta-like 1Y [Homo sapiens] 51 1e-06
gi|16554629 WD repeat domain 5 [Homo sapiens] 50 2e-06
gi|16554627 WD repeat domain 5 [Homo sapiens] 50 2e-06
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 50 2e-06
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 49 4e-06
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 49 4e-06
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 49 4e-06
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 49 4e-06
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 49 4e-06
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 49 4e-06
>gi|55743159 WD repeat domain 33 isoform 3 [Homo sapiens]
Length = 257
Score = 549 bits (1414), Expect = e-156
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN
Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC
Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD
Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL
Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
Query: 241 RDTCFHHCRCYFLSVKR 257
RDTCFHHCRCYFLSVKR
Sbjct: 241 RDTCFHHCRCYFLSVKR 257
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 510 bits (1314), Expect = e-145
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN
Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC
Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD
Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL
Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
Query: 241 R 241
R
Sbjct: 241 R 241
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/114 (21%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTA--DHGGY 184
++P + T + G +W+ L + E IL+ H + V+ + W +++ D
Sbjct: 210 FSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQP 269
Query: 185 VKYWQSNM-NNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
+K+W ++ AHK + E + N T S D +++D EE
Sbjct: 270 IKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEE 323
>gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens]
Length = 326
Score = 441 bits (1135), Expect = e-124
Identities = 209/210 (99%), Positives = 209/210 (99%)
Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN
Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60
Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC
Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD
Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASF 210
HGGYVKYWQSNMNNVKMFQAHKEAIREA F
Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREARF 210
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 62.8 bits (151), Expect = 3e-10
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
+ + ++P+G+ L +GA G +++ T L+ H P+R++T+S + ++TA
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210
Query: 182 GGYVK-YWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
GY+K Y + N H + +F P D F + S D +V++WD
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWD 260
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 55.1 bits (131), Expect = 6e-08
Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 8/133 (6%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W N+ +
Sbjct: 266 KGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASC 325
Query: 179 ADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEER 238
+ +K FQ H + + PT N A+CSDD T++IW
Sbjct: 326 STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS-------- 377
Query: 239 ILRDTCFHHCRCY 251
+ +D C H + +
Sbjct: 378 MKQDNCVHDLQAH 390
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/119 (22%), Positives = 49/119 (41%), Gaps = 10/119 (8%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWS---------HN 172
V ++W P G L + + +W+ N LQAH+ + + WS +
Sbjct: 352 VNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNA 411
Query: 173 DMWMLTADHGGYVKYWQSNMN-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + +A V+ W + + H+E + +FSP A+ S D V IW+
Sbjct: 412 NLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470
Score = 39.3 bits (90), Expect = 0.003
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 14/123 (11%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWN----GLTFNFETILQ------AHDSP----VRAM 167
VF+ W P L +G+ +WN + + + +L+ D P V ++
Sbjct: 172 VFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSL 231
Query: 168 TWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVR 227
W+ + T + G+ + W + N HK I ++ N + D T
Sbjct: 232 DWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTI 291
Query: 228 IWD 230
IWD
Sbjct: 292 IWD 294
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 55.1 bits (131), Expect = 6e-08
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
V++ P L TG++ LW+ N + H PV ++ +S N ++ +A
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQR 491
Query: 185 VKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+K W + K + H + I +FSP A+ S D +VR+WD
Sbjct: 492 LKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWD 538
Score = 44.7 bits (104), Expect = 8e-05
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 156 ILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTD 214
IL+ H PV + + + +L+ ++YW + N ++Q H + + SP
Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYS 396
Query: 215 NKFATCSDDGTVRIWDFLRCHEERI 239
FA+ S D T R+W F R + RI
Sbjct: 397 LYFASGSHDRTARLWSFDRTYPLRI 421
Score = 43.1 bits (100), Expect = 2e-04
Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV+ R+ + L++ + W+ +F + Q H PV + S ++ +
Sbjct: 344 PVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGS 403
Query: 181 HGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
H + W + ++++ H + F P N AT S D TVR+W
Sbjct: 404 HDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453
Score = 29.3 bits (64), Expect = 3.5
Identities = 14/68 (20%), Positives = 30/68 (44%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV + ++P G+ L + LW+ + L+ H + ++T+S + + +A
Sbjct: 470 PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASAS 529
Query: 181 HGGYVKYW 188
V+ W
Sbjct: 530 MDNSVRVW 537
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 54.3 bits (129), Expect = 1e-07
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 126 RWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYV 185
R+ P + TG++ LW+ L N I H P+ ++T+S N ++ T G V
Sbjct: 634 RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 186 KYWQSNMN-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
W V + H + + FS A+ S D TVR+WD ++ E+
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFED 746
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 1/120 (0%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV+ ++P+ L++ + G LW+ TF + H+ PV +S + ++
Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGG 604
Query: 181 HGGYVKYWQSN-MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERI 239
H + W ++ +++F H + F P N AT S D TVR+WD L + RI
Sbjct: 605 HDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRI 664
Score = 36.2 bits (82), Expect = 0.029
Identities = 15/41 (36%), Positives = 23/41 (56%)
Query: 189 QSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+ + +K+ H + ASFSP N + S+DGTVR+W
Sbjct: 530 EKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
Score = 35.4 bits (80), Expect = 0.049
Identities = 18/75 (24%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 156 ILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTD 214
IL H PV ++S + ++L++ G V+ W + ++ H + + FSP
Sbjct: 538 ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYG 597
Query: 215 NKFATCSDDGTVRIW 229
F + D R+W
Sbjct: 598 YYFVSGGHDRVARLW 612
Score = 32.0 bits (71), Expect = 0.54
Identities = 18/72 (25%), Positives = 33/72 (45%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+ + ++P GR L TGA+ G LW+ L+ H V ++ +S + + +
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILAS 728
Query: 179 ADHGGYVKYWQS 190
V+ W +
Sbjct: 729 GSMDNTVRLWDA 740
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRA--MT 168
++ ++V C F + + R + T + + +WN +T H V T
Sbjct: 653 IKAHEDEVLCCAF----STDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFT 708
Query: 169 WSHNDMWMLTADHGGYVKYWQSNMNNVK--MFQAHKEAIREASFSPTDNKFATCSDDGTV 226
S + + + T ++K W N + MF H ++ FSP D A+CS DGT+
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDKLLASCSADGTL 767
Query: 227 RIWDFLRCHEER 238
++WD +E +
Sbjct: 768 KLWDATSANERK 779
Score = 42.4 bits (98), Expect = 4e-04
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V+ +++T + + L++ + E +WN + L+ H V+ N +L+
Sbjct: 960 KKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQETVKDFRLLKNSR-LLS 1017
Query: 179 ADHGGYVKYWQS-NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF---LRC 234
G VK W N K F H+ + S KF++ S D T +IW F L
Sbjct: 1018 WSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPL 1077
Query: 235 HEER 238
HE R
Sbjct: 1078 HELR 1081
Score = 41.2 bits (95), Expect = 9e-04
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 13/118 (11%)
Query: 126 RWTPEGRRLVTGASSGEFTLWNGLT-------------FNFETILQAHDSPVRAMTWSHN 172
R++P+ + L + ++ G LW+ + N E + + V+ +WS +
Sbjct: 750 RFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSAD 809
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ A + + + V + H + FSP + F T SDD T+R+W+
Sbjct: 810 GARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNM 192
RL++ + G +WN +T N E H V + SH+ + K W ++
Sbjct: 1014 RLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 193 N-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+ + H +R ++FS AT D+G +RIW+
Sbjct: 1074 LLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWN 1112
Score = 31.6 bits (70), Expect = 0.71
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 145 LWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQA---H 201
L NG T + + +A V S + ++ D G ++ + + N ++FQ+ H
Sbjct: 905 LINGRTGQIDYLTEAQ---VSCCCLSPHLQYIAFGDENGAIEILE--LVNNRIFQSRFQH 959
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWD-------FLRCHEERI 239
K+ + F+ + + SDD +++W+ FLR H+E +
Sbjct: 960 KKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETV 1004
Score = 29.6 bits (65), Expect = 2.7
Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF--------ETILQAHDSPVRAMTW 169
V+C F V + L TG +GE +WN E H V + +
Sbjct: 1087 VRCSAFSV----DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCF 1142
Query: 170 SHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRI 228
S + +++A GGY+K+W + + F + +++ SP + T + G + I
Sbjct: 1143 SPDGKMLISA--GGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYI 1200
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRA--MT 168
++ ++V C F + + R + T + + +WN +T H V T
Sbjct: 653 IKAHEDEVLCCAF----STDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFT 708
Query: 169 WSHNDMWMLTADHGGYVKYWQSNMNNVK--MFQAHKEAIREASFSPTDNKFATCSDDGTV 226
S + + + T ++K W N + MF H ++ FSP D A+CS DGT+
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDKLLASCSADGTL 767
Query: 227 RIWDFLRCHEER 238
++WD +E +
Sbjct: 768 KLWDATSANERK 779
Score = 42.4 bits (98), Expect = 4e-04
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V+ +++T + + L++ + E +WN + L+ H V+ N +L+
Sbjct: 1003 KKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQETVKDFRLLKNSR-LLS 1060
Query: 179 ADHGGYVKYWQS-NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF---LRC 234
G VK W N K F H+ + S KF++ S D T +IW F L
Sbjct: 1061 WSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPL 1120
Query: 235 HEER 238
HE R
Sbjct: 1121 HELR 1124
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNM 192
RL++ + G +WN +T N E H V + SH+ + K W ++
Sbjct: 1057 RLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1116
Query: 193 N-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+ + H +R ++FS AT D+G +RIW+
Sbjct: 1117 LLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWN 1155
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWML 177
VKC W+ +G R++ A + F + I H S ++ +S + +
Sbjct: 801 VKC----CSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAV 856
Query: 178 TADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
A V+ W ++ + V + H + FSP + F T SDD T+R+W+
Sbjct: 857 VALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
Score = 31.6 bits (70), Expect = 0.71
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 145 LWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQA---H 201
L NG T + + +A V S + ++ D G ++ + + N ++FQ+ H
Sbjct: 948 LINGRTGQIDYLTEAQ---VSCCCLSPHLQYIAFGDENGAIEILE--LVNNRIFQSRFQH 1002
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWD-------FLRCHEERI 239
K+ + F+ + + SDD +++W+ FLR H+E +
Sbjct: 1003 KKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETV 1047
Score = 29.6 bits (65), Expect = 2.7
Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF--------ETILQAHDSPVRAMTW 169
V+C F V + L TG +GE +WN E H V + +
Sbjct: 1130 VRCSAFSV----DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCF 1185
Query: 170 SHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRI 228
S + +++A GGY+K+W + + F + +++ SP + T + G + I
Sbjct: 1186 SPDGKMLISA--GGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYI 1243
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRA--MT 168
++ ++V C F + + R + T + + +WN +T H V T
Sbjct: 642 IKAHEDEVLCCAF----STDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFT 697
Query: 169 WSHNDMWMLTADHGGYVKYWQSNMNNVK--MFQAHKEAIREASFSPTDNKFATCSDDGTV 226
S + + + T ++K W N + MF H ++ FSP D A+CS DGT+
Sbjct: 698 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDKLLASCSADGTL 756
Query: 227 RIWDFLRCHEER 238
++WD +E +
Sbjct: 757 KLWDATSANERK 768
Score = 42.4 bits (98), Expect = 4e-04
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V+ +++T + + L++ + E +WN + L+ H V+ N +L+
Sbjct: 949 KKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQETVKDFRLLKNSR-LLS 1006
Query: 179 ADHGGYVKYWQS-NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF---LRC 234
G VK W N K F H+ + S KF++ S D T +IW F L
Sbjct: 1007 WSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPL 1066
Query: 235 HEER 238
HE R
Sbjct: 1067 HELR 1070
Score = 41.2 bits (95), Expect = 9e-04
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 13/118 (11%)
Query: 126 RWTPEGRRLVTGASSGEFTLWNGLT-------------FNFETILQAHDSPVRAMTWSHN 172
R++P+ + L + ++ G LW+ + N E + + V+ +WS +
Sbjct: 739 RFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSAD 798
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ A + + + V + H + FSP + F T SDD T+R+W+
Sbjct: 799 GARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 856
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNM 192
RL++ + G +WN +T N E H V + SH+ + K W ++
Sbjct: 1003 RLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1062
Query: 193 N-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+ + H +R ++FS AT D+G +RIW+
Sbjct: 1063 LLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWN 1101
Score = 31.6 bits (70), Expect = 0.71
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 145 LWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQA---H 201
L NG T + + +A V S + ++ D G ++ + + N ++FQ+ H
Sbjct: 894 LINGRTGQIDYLTEAQ---VSCCCLSPHLQYIAFGDENGAIEILE--LVNNRIFQSRFQH 948
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWD-------FLRCHEERI 239
K+ + F+ + + SDD +++W+ FLR H+E +
Sbjct: 949 KKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETV 993
Score = 29.6 bits (65), Expect = 2.7
Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF--------ETILQAHDSPVRAMTW 169
V+C F V + L TG +GE +WN E H V + +
Sbjct: 1076 VRCSAFSV----DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCF 1131
Query: 170 SHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRI 228
S + +++A GGY+K+W + + F + +++ SP + T + G + I
Sbjct: 1132 SPDGKMLISA--GGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYI 1189
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRA--MT 168
++ ++V C F + + R + T + + +WN +T H V T
Sbjct: 642 IKAHEDEVLCCAF----STDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFT 697
Query: 169 WSHNDMWMLTADHGGYVKYWQSNMNNVK--MFQAHKEAIREASFSPTDNKFATCSDDGTV 226
S + + + T ++K W N + MF H ++ FSP D A+CS DGT+
Sbjct: 698 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDKLLASCSADGTL 756
Query: 227 RIWDFLRCHEER 238
++WD +E +
Sbjct: 757 KLWDATSANERK 768
Score = 42.4 bits (98), Expect = 4e-04
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V+ +++T + + L++ + E +WN + L+ H V+ N +L+
Sbjct: 992 KKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQETVKDFRLLKNSR-LLS 1049
Query: 179 ADHGGYVKYWQS-NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF---LRC 234
G VK W N K F H+ + S KF++ S D T +IW F L
Sbjct: 1050 WSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPL 1109
Query: 235 HEER 238
HE R
Sbjct: 1110 HELR 1113
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNM 192
RL++ + G +WN +T N E H V + SH+ + K W ++
Sbjct: 1046 RLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1105
Query: 193 N-NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+ + H +R ++FS AT D+G +RIW+
Sbjct: 1106 LLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWN 1144
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWML 177
VKC W+ +G R++ A + F + I H S ++ +S + +
Sbjct: 790 VKC----CSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAV 845
Query: 178 TADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
A V+ W ++ + V + H + FSP + F T SDD T+R+W+
Sbjct: 846 VALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
Score = 31.6 bits (70), Expect = 0.71
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 145 LWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQA---H 201
L NG T + + +A V S + ++ D G ++ + + N ++FQ+ H
Sbjct: 937 LINGRTGQIDYLTEAQ---VSCCCLSPHLQYIAFGDENGAIEILE--LVNNRIFQSRFQH 991
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWD-------FLRCHEERI 239
K+ + F+ + + SDD +++W+ FLR H+E +
Sbjct: 992 KKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETV 1036
Score = 29.6 bits (65), Expect = 2.7
Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 118 VKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF--------ETILQAHDSPVRAMTW 169
V+C F V + L TG +GE +WN E H V + +
Sbjct: 1119 VRCSAFSV----DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCF 1174
Query: 170 SHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRI 228
S + +++A GGY+K+W + + F + +++ SP + T + G + I
Sbjct: 1175 SPDGKMLISA--GGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYI 1232
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 52.8 bits (125), Expect = 3e-07
Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
V+++P G L + + LW + +AH +PVR++ +S + ++ TA
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKS 125
Query: 185 VKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+K W + H +R A FSP +CS+D T++IWD
Sbjct: 126 IKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172
Score = 45.1 bits (105), Expect = 6e-05
Identities = 35/121 (28%), Positives = 54/121 (44%), Gaps = 9/121 (7%)
Query: 115 TNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDM 174
T+ V+C F +P+GR +V+ + +W+ T N + + DS A N
Sbjct: 144 THWVRCAKF----SPDGRLIVSCSEDKTIKIWD--TTNKQCVNNFSDSVGFANFVDFNPS 197
Query: 175 WMLTADHGG--YVKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
A G VK W +N + + +Q H + SF P+ N T S DGT++I D
Sbjct: 198 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 232 L 232
L
Sbjct: 258 L 258
Score = 42.0 bits (97), Expect = 5e-04
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 1/107 (0%)
Query: 128 TPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKY 187
+P G++L T + LWN H V ++ +S + + +A V+
Sbjct: 27 SPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRL 86
Query: 188 W-QSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLR 233
W F+AH +R FS AT S+D ++++W R
Sbjct: 87 WIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Score = 39.7 bits (91), Expect = 0.003
Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Query: 154 ETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMN-NVKMFQAHKEAIREASFSP 212
E + H + + ++ S N + TA ++ W + + HK+ + FSP
Sbjct: 11 ERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSP 70
Query: 213 TDNKFATCSDDGTVRIW 229
N A+ S D TVR+W
Sbjct: 71 HGNLLASASRDRTVRLW 87
Score = 39.3 bits (90), Expect = 0.003
Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 1/111 (0%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV V ++ +G+ L T + +W+ F L H VR +S + +++
Sbjct: 104 PVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163
Query: 181 HGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+K W +N V F F+P+ A+ D TV++WD
Sbjct: 164 EDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214
Score = 30.8 bits (68), Expect = 1.2
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 196 KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
+ F+ HK AI SP + AT S D + +W+F
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNF 47
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/115 (21%), Positives = 42/115 (36%), Gaps = 5/115 (4%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
V + P G + + S +W+ Q H V +++ + +++TA G
Sbjct: 192 VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGT 251
Query: 185 VKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW----DFLRC 234
+K + Q H + SFS FA+ D V +W D L C
Sbjct: 252 LKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHC 306
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/86 (20%), Positives = 34/86 (39%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
+ + P G L+T +S G + + L LQ H PV +++S +
Sbjct: 234 ISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQ 293
Query: 185 VKYWQSNMNNVKMFQAHKEAIREASF 210
V W++N + + K ++ F
Sbjct: 294 VLLWRTNFDELHCKGLTKRNLKRLHF 319
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V V ++P G L +G+ +W T+ +AH + VR++ + + +T
Sbjct: 23 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVT 82
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
A VK W ++ + H +R A FSP + SDD TV++WD
Sbjct: 83 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 135
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Query: 116 NKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMW 175
N V+C F +P+GR +V+ + LW+ + H V + + +
Sbjct: 108 NWVRCAKF----SPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTC 163
Query: 176 MLTADHGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFL 232
+ A VK W + + + +Q H A+ SF P+ N T S D T++I D +
Sbjct: 164 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLM 221
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 160 HDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVK-MFQAHKEAIREASFSPTDNKFA 218
H V + +S + + + V+ W N+ +F+AH +R F F
Sbjct: 22 HKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV 81
Query: 219 TCSDDGTVRIW 229
T SDD TV++W
Sbjct: 82 TASDDKTVKVW 92
Score = 33.9 bits (76), Expect = 0.14
Identities = 15/32 (46%), Positives = 21/32 (65%)
Query: 198 FQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
F HK+A+ +FSP+ + A+ S D TVRIW
Sbjct: 19 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 50
Score = 29.3 bits (64), Expect = 3.5
Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 1/109 (0%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
V V + P G + +W+ T Q H + V +++ + +++TA
Sbjct: 152 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASS 211
Query: 182 GGYVKYWQSNMNNVKM-FQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+K + H+ +FS T FA+ D V +W
Sbjct: 212 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 260
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V V ++P G L +G+ +W T+ +AH + VR++ + + +T
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVT 120
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
A VK W ++ + H +R A FSP + SDD TV++WD
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Query: 116 NKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMW 175
N V+C F +P+GR +V+ + LW+ + H V + + +
Sbjct: 146 NWVRCAKF----SPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTC 201
Query: 176 MLTADHGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFL 232
+ A VK W + + + +Q H A+ SF P+ N T S D T++I D +
Sbjct: 202 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLM 259
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 132 RRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN 191
++L +G+ +W+ + H V + +S + + + V+ W N
Sbjct: 32 KQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN 91
Query: 192 MNNVK-MFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+ +F+AH +R F F T SDD TV++W
Sbjct: 92 VKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Score = 29.3 bits (64), Expect = 3.5
Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 1/109 (0%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
V V + P G + +W+ T Q H + V +++ + +++TA
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASS 249
Query: 182 GGYVKYWQSNMNNVKM-FQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+K + H+ +FS T FA+ D V +W
Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K V V ++P G L +G+ +W T+ +AH + VR++ + + +T
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVT 120
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
A VK W ++ + H +R A FSP + SDD TV++WD
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Query: 116 NKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMW 175
N V+C F +P+GR +V+ + LW+ + H V + + +
Sbjct: 146 NWVRCAKF----SPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTC 201
Query: 176 MLTADHGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFL 232
+ A VK W + + + +Q H A+ SF P+ N T S D T++I D +
Sbjct: 202 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLM 259
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 132 RRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN 191
++L +G+ +W+ + H V + +S + + + V+ W N
Sbjct: 32 KQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN 91
Query: 192 MNNVK-MFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+ +F+AH +R F F T SDD TV++W
Sbjct: 92 VKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Score = 29.3 bits (64), Expect = 3.5
Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 1/109 (0%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
V V + P G + +W+ T Q H + V +++ + +++TA
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASS 249
Query: 182 GGYVKYWQSNMNNVKM-FQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
+K + H+ +FS T FA+ D V +W
Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 52.4 bits (124), Expect = 4e-07
Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV R++P+G + + LW+ +L+ H V +++S + + +
Sbjct: 65 PVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGG 124
Query: 181 HGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERI 239
V W + ++ H+++I+ + FSPT N AT S D TV IWD LR +
Sbjct: 125 WDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWD-LRMVTPAV 183
Query: 240 LRDTCFHH-----CRCYFLS 254
H C CY S
Sbjct: 184 SHQALEGHSANISCLCYSAS 203
Score = 43.1 bits (100), Expect = 2e-04
Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVK 186
++P+G+ L+TG+ G W + L H PV+ +S + +A V+
Sbjct: 29 FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVR 88
Query: 187 YWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
W + +++ + H+ ++ SFSP + A+ D V +WD
Sbjct: 89 LWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 160 HDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKM-FQAHKEAIREASFSPTDNKFA 218
H V + +S + +LT G V W++ + H ++ FSP + FA
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 219 TCSDDGTVRIWDFLRCHEERILR 241
+ S D TVR+WD R R+L+
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLK 102
Score = 33.5 bits (75), Expect = 0.19
Identities = 19/95 (20%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 134 LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMN 193
L +G+ +W T + L+ H + V+++ +S +++W+ +A + VK W N
Sbjct: 206 LASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTG 265
Query: 194 N-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVR 227
++ + + +F+P + + D T R
Sbjct: 266 KCLETLKGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 29.3 bits (64), Expect = 3.5
Identities = 13/39 (33%), Positives = 19/39 (48%)
Query: 192 MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+ VK F H + ++FSP T S+DG V W+
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWE 49
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 51.6 bits (122), Expect = 7e-07
Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 6/111 (5%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWN---GLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
V W P G L T + +W + ++L +H V+ + W + + +A +
Sbjct: 111 VAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASY 170
Query: 182 GGYVKYWQSNMNN---VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
VK ++ ++ + H+ + +F P+ + A+CSDD TVRIW
Sbjct: 171 DDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 50.1 bits (118), Expect = 2e-06
Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 127 WTPEGRRLVTGASSGEFTLWN--GLTFNFETIL-QAHDSPVRAMTWSHNDMWMLTADHGG 183
W P G L + +W G ++ +++L + H VR + WS ++ +A
Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83
Query: 184 YVKYWQSNMNN---VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
W+ N ++ V + H+ ++ +++P+ N ATCS D +V +W+
Sbjct: 84 TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWE 133
Score = 44.7 bits (104), Expect = 8e-05
Identities = 24/111 (21%), Positives = 52/111 (46%), Gaps = 6/111 (5%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFE--TILQAHDSPVRAMTWSHNDMWMLTADHG 182
V W+P G L + + +W +FE T L+ H++ V+++ W+ + + T
Sbjct: 67 VAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRD 126
Query: 183 GYVKYWQSNMNN----VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
V W+ + + V + +H + ++ + P+ A+ S D TV+++
Sbjct: 127 KSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY 177
Score = 32.0 bits (71), Expect = 0.54
Identities = 24/107 (22%), Positives = 43/107 (40%), Gaps = 15/107 (14%)
Query: 138 ASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNN--- 194
A SG W + T+ H + + W + TA ++ +Q + N+
Sbjct: 233 ACSGSDPSWKCIC----TLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQ 288
Query: 195 -------VKMFQAHKEAIREASFSPTD-NKFATCSDDGTVRIWDFLR 233
+ QAH + + +++P + A+CSDDG V W + R
Sbjct: 289 QPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQR 335
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)
[Homo sapiens]
Length = 514
Score = 51.6 bits (122), Expect = 7e-07
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 129 PEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYW 188
P + VTG++ +W+ + + L H S VR + S ++ + VK W
Sbjct: 214 PGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCW 273
Query: 189 QSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
N V + + H A+ PT + TCS D T RIWD
Sbjct: 274 DLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWD 316
Score = 31.6 bits (70), Expect = 0.71
Identities = 16/76 (21%), Positives = 28/76 (36%), Gaps = 1/76 (1%)
Query: 156 ILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKM-FQAHKEAIREASFSPTD 214
++ H VR + + W +T +K W +K+ H +R S
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 215 NKFATCSDDGTVRIWD 230
+C +D V+ WD
Sbjct: 259 PYLFSCGEDKQVKCWD 274
Score = 31.6 bits (70), Expect = 0.71
Identities = 23/111 (20%), Positives = 47/111 (42%), Gaps = 3/111 (2%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
V VR +++TG+ LW+ + L H VRA+ H + +
Sbjct: 333 VATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVV-LHPRHYTFASGS 391
Query: 182 GGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
+K W+ + + ++ H I + + +D + +D+GT+ +WD+
Sbjct: 392 PDNIKQWKFPDGSFIQNLSGHNAIINTLTVN-SDGVLVSGADNGTMHLWDW 441
Score = 30.0 bits (66), Expect = 2.1
Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 2/99 (2%)
Query: 134 LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMN 193
LVT + +W+ T L H + V + + ++T H ++ W
Sbjct: 303 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG 362
Query: 194 NVKM-FQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
++ HK+++R P FA+ S D ++ W F
Sbjct: 363 KTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKF 400
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 1e-06
Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 10/134 (7%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N M +
Sbjct: 276 KGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFAS 334
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
+ + ++ VK FQ H + + P+ A+CSDD T++IW
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS------- 387
Query: 238 RILRDTCFHHCRCY 251
+ +D C H + +
Sbjct: 388 -MKQDACVHDLQAH 400
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 182 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 240
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ + + + G+ + W N N HK I ++ N + D T
Sbjct: 241 LDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTT 300
Query: 227 RIWD 230
IWD
Sbjct: 301 IIWD 304
Score = 32.7 bits (73), Expect = 0.32
Identities = 21/118 (17%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 404 IYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + YV W + ++ I E ++ +K + DG+V + D
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLD 521
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 1e-06
Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 10/134 (7%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N M +
Sbjct: 276 KGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFAS 334
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
+ + ++ VK FQ H + + P+ A+CSDD T++IW
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS------- 387
Query: 238 RILRDTCFHHCRCY 251
+ +D C H + +
Sbjct: 388 -MKQDACVHDLQAH 400
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 182 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 240
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ + + + G+ + W N N HK I ++ N + D T
Sbjct: 241 LDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTT 300
Query: 227 RIWD 230
IWD
Sbjct: 301 IIWD 304
Score = 32.7 bits (73), Expect = 0.32
Identities = 21/118 (17%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 404 IYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + YV W + ++ I E ++ +K + DG+V + D
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLD 521
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 1e-06
Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 10/134 (7%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N M +
Sbjct: 276 KGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFAS 334
Query: 179 ADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
+ + ++ VK FQ H + + P+ A+CSDD T++IW
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS------- 387
Query: 238 RILRDTCFHHCRCY 251
+ +D C H + +
Sbjct: 388 -MKQDACVHDLQAH 400
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 182 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 240
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ + + + G+ + W N N HK I ++ N + D T
Sbjct: 241 LDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTT 300
Query: 227 RIWD 230
IWD
Sbjct: 301 IIWD 304
Score = 32.7 bits (73), Expect = 0.32
Identities = 21/118 (17%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 404 IYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + YV W + ++ I E ++ +K + DG+V + D
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLD 521
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.1 bits (118), Expect = 2e-06
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
V+++P G L + ++ +W FE + H + + WS + +++A
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 185 VKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+K W S+ +K + H + +F+P N + S D +VRIWD
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Score = 43.5 bits (101), Expect = 2e-04
Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 2/112 (1%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
VF + P+ +V+G+ +W+ T L AH PV A+ ++ + ++++ +
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 191
Query: 182 GGYVKYWQSNMNNV--KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
G + W + + + FSP + D T+++WD+
Sbjct: 192 DGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243
Score = 42.0 bits (97), Expect = 5e-04
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 157 LQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDN 215
L H V ++ +S N W+ ++ +K W + K HK I + ++S N
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 216 KFATCSDDGTVRIWD 230
+ SDD T++IWD
Sbjct: 101 LLVSASDDKTLKIWD 115
Score = 33.1 bits (74), Expect = 0.24
Identities = 23/115 (20%), Positives = 46/115 (40%), Gaps = 6/115 (5%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWN---GLTFNFETILQAHDSPVRAMTWSHNDMWML 177
PV V+++P G+ ++ LW+ G T + + A W++
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 178 TADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCS--DDGTVRIW 229
+ V W V+ Q H + + + PT+N A+ + +D T+++W
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.1 bits (118), Expect = 2e-06
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Query: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
V+++P G L + ++ +W FE + H + + WS + +++A
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 185 VKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
+K W S+ +K + H + +F+P N + S D +VRIWD
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Score = 43.5 bits (101), Expect = 2e-04
Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 2/112 (1%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
VF + P+ +V+G+ +W+ T L AH PV A+ ++ + ++++ +
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 191
Query: 182 GGYVKYWQSNMNNV--KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
G + W + + + FSP + D T+++WD+
Sbjct: 192 DGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243
Score = 42.0 bits (97), Expect = 5e-04
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 157 LQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNV-KMFQAHKEAIREASFSPTDN 215
L H V ++ +S N W+ ++ +K W + K HK I + ++S N
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 216 KFATCSDDGTVRIWD 230
+ SDD T++IWD
Sbjct: 101 LLVSASDDKTLKIWD 115
Score = 33.1 bits (74), Expect = 0.24
Identities = 23/115 (20%), Positives = 46/115 (40%), Gaps = 6/115 (5%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWN---GLTFNFETILQAHDSPVRAMTWSHNDMWML 177
PV V+++P G+ ++ LW+ G T + + A W++
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 178 TADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCS--DDGTVRIW 229
+ V W V+ Q H + + + PT+N A+ + +D T+++W
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 50.1 bits (118), Expect = 2e-06
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 140 SGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN-MNNVKMF 198
+G +WN T + D PVRA + W++T ++ + N + V MF
Sbjct: 36 NGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMF 95
Query: 199 QAHKEAIREASFSPTDNKFATCSDDGTVRIWDF 231
+AH + IR + PT T SDD +++WD+
Sbjct: 96 EAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDW 128
Score = 45.1 bits (105), Expect = 6e-05
Identities = 26/112 (23%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV ++ +VTGA + ++N T + +AH +R + ++LT+
Sbjct: 59 PVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSS 118
Query: 181 HGGYVKY--WQSNMNNVKMFQAHKEAIREASFSPTD-NKFATCSDDGTVRIW 229
+K W + ++F+ H + + +P D N+FA+ S D T+++W
Sbjct: 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVW 170
Score = 36.2 bits (82), Expect = 0.029
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 15/96 (15%)
Query: 137 GASSGEFTLWNGLTFNFETILQAHDSPVRAMTW--SHNDMWMLTADHGGYVKYWQ-SNMN 193
G+SS FTL + H+ V + + + ++++ VK W N
Sbjct: 173 GSSSPNFTL------------EGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKT 220
Query: 194 NVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
V+ + H + + ASF P T S+DGTVRIW
Sbjct: 221 CVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 48.9 bits (115), Expect = 4e-06
Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 3/133 (2%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N +
Sbjct: 278 KGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASC 337
Query: 179 ADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEER 238
+ VK FQ H + + P+ A+CSDD T++IW +E
Sbjct: 338 STDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM---KQEV 394
Query: 239 ILRDTCFHHCRCY 251
+ D H+ Y
Sbjct: 395 CIHDLQAHNKEIY 407
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 184 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 242
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ N + T + G+ + W + N HK I ++ N + D T
Sbjct: 243 LDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTT 302
Query: 227 RIWD 230
IWD
Sbjct: 303 IIWD 306
Score = 37.0 bits (84), Expect = 0.017
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 158 QAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPT--- 213
Q H + V A+ W + M + + +K W + QAH + I +SPT
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 417
Query: 214 ------DNKFATCSDDGTVRIWDFLR 233
+ A+ S D TVR+WD R
Sbjct: 418 TSNPNSNIMLASASFDSTVRLWDIER 443
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 406 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 465
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + V W + N+ I E ++ +K + DG+V + D
Sbjct: 466 GKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLD 523
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 48.9 bits (115), Expect = 4e-06
Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 3/133 (2%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N +
Sbjct: 278 KGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASC 337
Query: 179 ADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEER 238
+ VK FQ H + + P+ A+CSDD T++IW +E
Sbjct: 338 STDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM---KQEV 394
Query: 239 ILRDTCFHHCRCY 251
+ D H+ Y
Sbjct: 395 CIHDLQAHNKEIY 407
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 184 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 242
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ N + T + G+ + W + N HK I ++ N + D T
Sbjct: 243 LDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTT 302
Query: 227 RIWD 230
IWD
Sbjct: 303 IIWD 306
Score = 37.0 bits (84), Expect = 0.017
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 158 QAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPT--- 213
Q H + V A+ W + M + + +K W + QAH + I +SPT
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 417
Query: 214 ------DNKFATCSDDGTVRIWDFLR 233
+ A+ S D TVR+WD R
Sbjct: 418 TSNPNSNIMLASASFDSTVRLWDIER 443
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 406 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 465
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + V W + N+ I E ++ +K + DG+V + D
Sbjct: 466 GKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLD 523
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 48.9 bits (115), Expect = 4e-06
Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 3/133 (2%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N +
Sbjct: 329 KGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASC 388
Query: 179 ADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEER 238
+ VK FQ H + + P+ A+CSDD T++IW +E
Sbjct: 389 STDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM---KQEV 445
Query: 239 ILRDTCFHHCRCY 251
+ D H+ Y
Sbjct: 446 CIHDLQAHNKEIY 458
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 235 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 293
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ N + T + G+ + W + N HK I ++ N + D T
Sbjct: 294 LDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTT 353
Query: 227 RIWD 230
IWD
Sbjct: 354 IIWD 357
Score = 37.0 bits (84), Expect = 0.017
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 158 QAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPT--- 213
Q H + V A+ W + M + + +K W + QAH + I +SPT
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 468
Query: 214 ------DNKFATCSDDGTVRIWDFLR 233
+ A+ S D TVR+WD R
Sbjct: 469 TSNPNSNIMLASASFDSTVRLWDIER 494
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 457 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 516
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + V W + N+ I E ++ +K + DG+V + D
Sbjct: 517 GKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLD 574
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 48.9 bits (115), Expect = 4e-06
Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 3/133 (2%)
Query: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
K P+F ++W +G +++ +W+ T + H +P + W +N +
Sbjct: 329 KGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASC 388
Query: 179 ADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEER 238
+ VK FQ H + + P+ A+CSDD T++IW +E
Sbjct: 389 STDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM---KQEV 445
Query: 239 ILRDTCFHHCRCY 251
+ D H+ Y
Sbjct: 446 CIHDLQAHNKEIY 458
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 16/124 (12%)
Query: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNF-----ETILQ------AHDSP----VRA 166
VF+ W P L +G+ +WN L N + +L+ HD P V +
Sbjct: 235 VFICAWNPVSDLLASGSGDSTARIWN-LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS 293
Query: 167 MTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTV 226
+ W+ N + T + G+ + W + N HK I ++ N + D T
Sbjct: 294 LDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTT 353
Query: 227 RIWD 230
IWD
Sbjct: 354 IIWD 357
Score = 37.0 bits (84), Expect = 0.017
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 158 QAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPT--- 213
Q H + V A+ W + M + + +K W + QAH + I +SPT
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 468
Query: 214 ------DNKFATCSDDGTVRIWDFLR 233
+ A+ S D TVR+WD R
Sbjct: 469 TSNPNSNIMLASASFDSTVRLWDIER 494
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 9/118 (7%)
Query: 122 VFVVRWTPEGRR---------LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHN 172
++ ++W+P G L + + LW+ L H PV ++ +S +
Sbjct: 457 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 516
Query: 173 DMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
++ + V W + N+ I E ++ +K + DG+V + D
Sbjct: 517 GKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLD 574
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 48.9 bits (115), Expect = 4e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV V +++P+ L +GA+ G LWN ++ D + A +S N + +T
Sbjct: 99 PVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGS 158
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFS--PTDN--------KFATCSDDGTVRIW 229
G + W M + +AH I FS P + + A+C D V+IW
Sbjct: 159 SCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIW 217
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Query: 143 FTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNV-KMFQAH 201
FT G +++ L H +PV A +SH+ +++ V + +N N+ H
Sbjct: 221 FTHILGFELKYKSTLSGHCAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQH 280
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWDF 231
+ +F+P AT S D TV IW F
Sbjct: 281 TRYVTTCAFAPNTLLLATGSMDKTVNIWQF 310
Score = 41.2 bits (95), Expect = 9e-04
Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETIL-QAHDSPVRAMTWSHNDMWMLTADHGGYV 185
++P G L + ++ G LWN ++ Q SPVR +S + + + G V
Sbjct: 62 FSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLASGAADGTV 121
Query: 186 KYWQSNMNNVKMFQAHKE-AIREASFSPTDNKFATCSDDGTVRIW-DFLRC-HEER 238
W + + + K+ ++ +FSP + F T S G + +W D +RC H E+
Sbjct: 122 VLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEK 177
Score = 30.4 bits (67), Expect = 1.6
Identities = 12/30 (40%), Positives = 18/30 (60%)
Query: 201 HKEAIREASFSPTDNKFATCSDDGTVRIWD 230
H A+ FSP+ + A+CS DGT +W+
Sbjct: 53 HTYAVHCCCFSPSGHILASCSTDGTTVLWN 82
Score = 28.1 bits (61), Expect = 7.9
Identities = 20/105 (19%), Positives = 43/105 (40%), Gaps = 2/105 (1%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV ++ +G+ LV+G+ +++ T N L H V ++ N + + T
Sbjct: 241 PVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGS 300
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIRE--ASFSPTDNKFATCSDD 223
V WQ ++ + + + +++ +S D C+ D
Sbjct: 301 MDKTVNIWQFDLETLCQARRTEHQLKQFTEDWSEEDVSTWLCAQD 345
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 48.9 bits (115), Expect = 4e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV V +++P+ L +GA+ G LWN ++ D + A +S N + +T
Sbjct: 99 PVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGS 158
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFS--PTDN--------KFATCSDDGTVRIW 229
G + W M + +AH I FS P + + A+C D V+IW
Sbjct: 159 SCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIW 217
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Query: 143 FTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNV-KMFQAH 201
FT G +++ L H +PV A +SH+ +++ V + +N N+ H
Sbjct: 221 FTHILGFELKYKSTLSGHCAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQH 280
Query: 202 KEAIREASFSPTDNKFATCSDDGTVRIWDF 231
+ +F+P AT S D TV IW F
Sbjct: 281 TRYVTTCAFAPNTLLLATGSMDKTVNIWQF 310
Score = 41.2 bits (95), Expect = 9e-04
Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETIL-QAHDSPVRAMTWSHNDMWMLTADHGGYV 185
++P G L + ++ G LWN ++ Q SPVR +S + + + G V
Sbjct: 62 FSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLASGAADGTV 121
Query: 186 KYWQSNMNNVKMFQAHKE-AIREASFSPTDNKFATCSDDGTVRIW-DFLRC-HEER 238
W + + + K+ ++ +FSP + F T S G + +W D +RC H E+
Sbjct: 122 VLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEK 177
Score = 30.4 bits (67), Expect = 1.6
Identities = 12/30 (40%), Positives = 18/30 (60%)
Query: 201 HKEAIREASFSPTDNKFATCSDDGTVRIWD 230
H A+ FSP+ + A+CS DGT +W+
Sbjct: 53 HTYAVHCCCFSPSGHILASCSTDGTTVLWN 82
Score = 28.1 bits (61), Expect = 7.9
Identities = 20/105 (19%), Positives = 43/105 (40%), Gaps = 2/105 (1%)
Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180
PV ++ +G+ LV+G+ +++ T N L H V ++ N + + T
Sbjct: 241 PVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGS 300
Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIRE--ASFSPTDNKFATCSDD 223
V WQ ++ + + + +++ +S D C+ D
Sbjct: 301 MDKTVNIWQFDLETLCQARRTEHQLKQFTEDWSEEDVSTWLCAQD 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.135 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,181,762
Number of Sequences: 37866
Number of extensions: 419005
Number of successful extensions: 2394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 1324
Number of HSP's gapped (non-prelim): 908
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.