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Search of human proteins with 53828918
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
(567 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens] 1150 0.0
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens] 1150 0.0
gi|66882524 farnesyltransferase, CAAX box, alpha isoform b [Homo... 80 7e-15
gi|4503771 farnesyltransferase, CAAX box, alpha isoform a [Homo ... 80 7e-15
gi|66882532 farnesyltransferase, CAAX box, alpha isoform c [Homo... 72 2e-12
gi|66472382 nischarin [Homo sapiens] 61 2e-09
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 60 5e-09
gi|153792604 protein prenyltransferase alpha subunit repeat cont... 56 8e-08
gi|61742786 leucine rich repeat and death domain containing prot... 55 2e-07
gi|61742784 leucine rich repeat and death domain containing prot... 55 2e-07
gi|61742782 leucine rich repeat and death domain containing prot... 55 2e-07
gi|110825984 malignant fibrous histiocytoma amplified sequence 1... 55 2e-07
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 54 4e-07
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 54 4e-07
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 54 4e-07
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 54 4e-07
gi|194394161 leucine rich repeat containing 57 [Homo sapiens] 52 2e-06
gi|95113664 leucine rich repeat containing 1 [Homo sapiens] 52 2e-06
gi|194440719 chondroadherin-like [Homo sapiens] 50 6e-06
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 50 6e-06
gi|21361633 leucine rich repeat containing 40 [Homo sapiens] 50 6e-06
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso... 50 7e-06
gi|16904383 leucine rich repeat containing 7 [Homo sapiens] 49 1e-05
gi|116235474 LKB1 interacting protein [Homo sapiens] 49 1e-05
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens] 49 2e-05
gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens] 48 2e-05
gi|157743290 leucine rich repeat containing 30 [Homo sapiens] 48 2e-05
gi|193083139 leucine rich repeat containing 32 precursor [Homo s... 47 5e-05
gi|5031707 leucine rich repeat containing 32 precursor [Homo sap... 47 5e-05
gi|45505137 podocan [Homo sapiens] 47 5e-05
>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 1150 bits (2976), Expect = 0.0
Identities = 567/567 (100%), Positives = 567/567 (100%)
Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60
MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP
Sbjct: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60
Query: 61 DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL 120
DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL
Sbjct: 61 DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL 120
Query: 121 PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS 180
PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS
Sbjct: 121 PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS 180
Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD 240
WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD
Sbjct: 181 WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD 240
Query: 241 PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW 300
PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW
Sbjct: 241 PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW 300
Query: 301 LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK 360
LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK
Sbjct: 301 LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK 360
Query: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT 420
STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT
Sbjct: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT 420
Query: 421 YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP 480
YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP
Sbjct: 421 YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP 480
Query: 481 ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL 540
ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL
Sbjct: 481 ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL 540
Query: 541 QGNPLCQAVGILEQLAELLPSVSSVLT 567
QGNPLCQAVGILEQLAELLPSVSSVLT
Sbjct: 541 QGNPLCQAVGILEQLAELLPSVSSVLT 567
>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 1150 bits (2976), Expect = 0.0
Identities = 567/567 (100%), Positives = 567/567 (100%)
Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60
MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP
Sbjct: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60
Query: 61 DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL 120
DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL
Sbjct: 61 DFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRL 120
Query: 121 PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS 180
PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS
Sbjct: 121 PEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSS 180
Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD 240
WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD
Sbjct: 181 WHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAD 240
Query: 241 PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW 300
PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW
Sbjct: 241 PQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVW 300
Query: 301 LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK 360
LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK
Sbjct: 301 LCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEK 360
Query: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT 420
STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT
Sbjct: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQTLKAVDPMRAT 420
Query: 421 YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP 480
YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP
Sbjct: 421 YLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP 480
Query: 481 ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL 540
ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL
Sbjct: 481 ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL 540
Query: 541 QGNPLCQAVGILEQLAELLPSVSSVLT 567
QGNPLCQAVGILEQLAELLPSVSSVLT
Sbjct: 541 QGNPLCQAVGILEQLAELLPSVSSVLT 567
>gi|66882524 farnesyltransferase, CAAX box, alpha isoform b [Homo
sapiens]
Length = 288
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 20/197 (10%)
Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Q E E +LT + N T+W+ RR +L+ L QK E E+ ++ +
Sbjct: 17 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSL--QKDLHE-------EMNYITAI 67
Query: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159
+ PK+Y WHHR L+ L +P ++ELE A L D +N+H W +R++V + +
Sbjct: 68 IEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 125
Query: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAF 219
EL + D L+ + N S W+ R ++ S G VL +E++
Sbjct: 126 D-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAVLEREVQYTLEMI 176
Query: 220 FTDPNDQSAWFYHRWLL 236
P+++SAW Y + +L
Sbjct: 177 KLVPHNESAWNYLKGIL 193
>gi|4503771 farnesyltransferase, CAAX box, alpha isoform a [Homo
sapiens]
Length = 379
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 20/197 (10%)
Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Q E E +LT + N T+W+ RR +L+ L QK E E+ ++ +
Sbjct: 108 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSL--QKDLHE-------EMNYITAI 158
Query: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159
+ PK+Y WHHR L+ L +P ++ELE A L D +N+H W +R++V + +
Sbjct: 159 IEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 216
Query: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAF 219
EL + D L+ + N S W+ R ++ S G VL +E++
Sbjct: 217 D-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAVLEREVQYTLEMI 267
Query: 220 FTDPNDQSAWFYHRWLL 236
P+++SAW Y + +L
Sbjct: 268 KLVPHNESAWNYLKGIL 284
>gi|66882532 farnesyltransferase, CAAX box, alpha isoform c [Homo
sapiens]
Length = 312
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/217 (26%), Positives = 101/217 (46%), Gaps = 31/217 (14%)
Query: 20 EREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQ 79
+++ K ++ A +AV A +D+ + L S P + + RR +L+ L Q
Sbjct: 32 QQQHKEEMAAEAGEAV-----ASPMDDGFVSLDS------PSYVLYRHFRRVLLKSL--Q 78
Query: 80 KSPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVD 139
K E E+ ++ + + PK+Y WHHR L+ L +P ++ELE A L D
Sbjct: 79 KDLHE-------EMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQD 129
Query: 140 ERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGP 199
+N+H W +R++V + + EL + D L+ + N S W+ R ++ S
Sbjct: 130 AKNYHAWQHRQWVIQEFKLWD-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNT 180
Query: 200 QGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLL 236
G VL +E++ P+++SAW Y + +L
Sbjct: 181 TGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGIL 217
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 28/227 (12%)
Query: 339 EGWCRDSTTDEQLFRCELSVEKSTVLQSELESC--KELQELEPENKWCLLTI-------- 388
EG S EQL +LS+ KS + Q E+ C K ++ L +K L T+
Sbjct: 196 EGPFGTSNIQEQLLPFDLSIFKS-LHQVEISHCDAKHIRGLVA-SKPTLATLSVRFSATS 253
Query: 389 ---ILLMRALDPLLYEKETLQYFQTLKAVDP--MRATYLDDLRSKFLLENSVLKMEYA-- 441
+L+ A + +E E + AV P T LD L NS+ +++ +
Sbjct: 254 MKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLD------LSHNSISEIDESVK 307
Query: 442 ---EVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAI 498
++ L L+H L V+ +L+ L + HLDLS+N+L +L L ++ L + N +
Sbjct: 308 LIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLL 367
Query: 499 ESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
ESL G+ L L L L +NR++Q ++ + S P L ++L NPL
Sbjct: 368 ESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPL 414
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 60.1 bits (144), Expect = 5e-09
Identities = 45/132 (34%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Query: 425 LRSKFLLENSVLKME----YAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPP 480
LR +L N + K+E E+R L L L + +LE L + L+LS+N ++T+
Sbjct: 131 LRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIEN 190
Query: 481 ALAALRCLEVLQASDNAIESLDGVTNLP---RLQELLLCNNRLQQPAVLQPLASCPRLVL 537
L+ L L LQ + N +E+++ + +L RL L L +N+L P +L L S P L +
Sbjct: 191 -LSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSILESMPDLRV 249
Query: 538 LNLQGNPLCQAV 549
LNL GNP+ + +
Sbjct: 250 LNLMGNPVIRQI 261
Score = 49.3 bits (116), Expect = 9e-06
Identities = 38/122 (31%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Query: 439 EYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAI 498
EY +R L L + + +LE + L L N LR + L L+ L+ L S+N I
Sbjct: 127 EYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIEN-LEPLQKLDALNLSNNYI 185
Query: 499 ESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPLC--QAVGILEQLA 556
++++ ++ LP L L + +N L+ +Q L C RL +L+L N L + + ILE +
Sbjct: 186 KTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSILESMP 245
Query: 557 EL 558
+L
Sbjct: 246 DL 247
>gi|153792604 protein prenyltransferase alpha subunit repeat
containing 1 [Homo sapiens]
Length = 402
Score = 56.2 bits (134), Expect = 8e-08
Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 35/175 (20%)
Query: 46 ESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESCLRVNPK 105
+ ++++T +L NPDF T WN R+E++ L + LG L L PK
Sbjct: 85 DELIDVTCTLLLLNPDFTTAWNVRKELILS-------GTLNPIKDLHLGKL--ALTKFPK 135
Query: 106 SYGTWHHRCWL------------------LGRLPEPNWTR----ELELCARFLEVDERNF 143
S TW HR W+ LG +P R E+E+C N+
Sbjct: 136 SPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNY 195
Query: 144 HCWDYRRFVATQAAVPPA----EELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQ 194
+ W +R +V A +EL+ T + + S++S +HYR LL L Q
Sbjct: 196 NAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQ 250
Score = 31.6 bits (70), Expect = 2.0
Identities = 21/101 (20%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 146 WDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPD------SGP 199
W+ R+ + + P ++L +T+ + +W +R +L QL + G
Sbjct: 105 WNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGN 164
Query: 200 QGRLPED----VLLKELELVQNAFFTDPNDQSAWFYHRWLL 236
G +P + ++ +E+E+ A P++ +AW + W+L
Sbjct: 165 LGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVL 205
>gi|61742786 leucine rich repeat and death domain containing protein
isoform 3 [Homo sapiens]
Length = 893
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/95 (45%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query: 446 LHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DG 503
L L+H L+ L L L +T L ++HNRL+TLPPAL AL L+ L S N +++L
Sbjct: 153 LLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPE 212
Query: 504 VTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVL 537
+ L L EL L +NRLQ PA L L S LVL
Sbjct: 213 IGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 247
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCN 517
L L + HLDLS N L TLP + +R L L S N + L + + LP L L + +
Sbjct: 121 LSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTH 180
Query: 518 NRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
NRLQ P L L++ RL L + L +G L L EL
Sbjct: 181 NRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLEL 222
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLD-GVTNLPRLQELLLCN 517
L L + LDLS N L TLPP + L L L + N ++SL + L L+ L+L +
Sbjct: 190 LGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHS 249
Query: 518 NRLQQPAVLQPLASCPRLVLLNLQGNPL 545
N L +V LA P L L+L+ N L
Sbjct: 250 NLL--ASVPADLARLPLLTRLDLRDNQL 275
Score = 32.0 bits (71), Expect = 1.6
Identities = 60/203 (29%), Positives = 79/203 (38%), Gaps = 34/203 (16%)
Query: 392 MRALDPLLYEKETLQYF---QTLKAVDPMRATYLDDLRSKFLLENSV--LKMEYAEVRVL 446
++ L P L TLQ Q L P L L L N + L A +R L
Sbjct: 183 LQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSL 242
Query: 447 HLA--HKDL--TVLCHLEQLLLVTHLDLSHNRLRTLPPAL-----AALRCLEVLQASDNA 497
L H +L +V L +L L+T LDL N+LR LPP L L+ + +AS +A
Sbjct: 243 RLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDA 302
Query: 498 IESLDG--VTNLPRL----------------QELLLCNNRLQQP--AVLQPLASCPRLVL 537
S + +PRL L C RLQ P A P+ RL+L
Sbjct: 303 PSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLL 362
Query: 538 LNLQGNPLCQAVGILEQLAELLP 560
PL +L + EL P
Sbjct: 363 PEPGLVPLGPHDALLSHVLELQP 385
>gi|61742784 leucine rich repeat and death domain containing protein
isoform 1 [Homo sapiens]
Length = 910
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/95 (45%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query: 446 LHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DG 503
L L+H L+ L L L +T L ++HNRL+TLPPAL AL L+ L S N +++L
Sbjct: 153 LLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPE 212
Query: 504 VTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVL 537
+ L L EL L +NRLQ PA L L S LVL
Sbjct: 213 IGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 247
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCN 517
L L + HLDLS N L TLP + +R L L S N + L + + LP L L + +
Sbjct: 121 LSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTH 180
Query: 518 NRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
NRLQ P L L++ RL L + L +G L L EL
Sbjct: 181 NRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLEL 222
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLD-GVTNLPRLQELLLCN 517
L L + LDLS N L TLPP + L L L + N ++SL + L L+ L+L +
Sbjct: 190 LGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHS 249
Query: 518 NRLQQPAVLQPLASCPRLVLLNLQGNPL 545
N L +V LA P L L+L+ N L
Sbjct: 250 NLL--ASVPADLARLPLLTRLDLRDNQL 275
Score = 32.0 bits (71), Expect = 1.6
Identities = 60/203 (29%), Positives = 79/203 (38%), Gaps = 34/203 (16%)
Query: 392 MRALDPLLYEKETLQYF---QTLKAVDPMRATYLDDLRSKFLLENSV--LKMEYAEVRVL 446
++ L P L TLQ Q L P L L L N + L A +R L
Sbjct: 183 LQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSL 242
Query: 447 HLA--HKDL--TVLCHLEQLLLVTHLDLSHNRLRTLPPAL-----AALRCLEVLQASDNA 497
L H +L +V L +L L+T LDL N+LR LPP L L+ + +AS +A
Sbjct: 243 RLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDA 302
Query: 498 IESLDG--VTNLPRL----------------QELLLCNNRLQQP--AVLQPLASCPRLVL 537
S + +PRL L C RLQ P A P+ RL+L
Sbjct: 303 PSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLL 362
Query: 538 LNLQGNPLCQAVGILEQLAELLP 560
PL +L + EL P
Sbjct: 363 PEPGLVPLGPHDALLSHVLELQP 385
>gi|61742782 leucine rich repeat and death domain containing protein
isoform 2 [Homo sapiens]
Length = 753
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/95 (45%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query: 446 LHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DG 503
L L+H L+ L L L +T L ++HNRL+TLPPAL AL L+ L S N +++L
Sbjct: 7 LLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPE 66
Query: 504 VTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVL 537
+ L L EL L +NRLQ PA L L S LVL
Sbjct: 67 IGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 101
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLD-GVTNLPRLQELLLCN 517
L L + LDLS N L TLPP + L L L + N ++SL + L L+ L+L +
Sbjct: 44 LGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHS 103
Query: 518 NRLQQPAVLQPLASCPRLVLLNLQGNPL 545
N L +V LA P L L+L+ N L
Sbjct: 104 NLL--ASVPADLARLPLLTRLDLRDNQL 129
Score = 32.0 bits (71), Expect = 1.6
Identities = 60/203 (29%), Positives = 79/203 (38%), Gaps = 34/203 (16%)
Query: 392 MRALDPLLYEKETLQYF---QTLKAVDPMRATYLDDLRSKFLLENSV--LKMEYAEVRVL 446
++ L P L TLQ Q L P L L L N + L A +R L
Sbjct: 37 LQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSL 96
Query: 447 HLA--HKDL--TVLCHLEQLLLVTHLDLSHNRLRTLPPAL-----AALRCLEVLQASDNA 497
L H +L +V L +L L+T LDL N+LR LPP L L+ + +AS +A
Sbjct: 97 RLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDA 156
Query: 498 IESLDG--VTNLPRL----------------QELLLCNNRLQQP--AVLQPLASCPRLVL 537
S + +PRL L C RLQ P A P+ RL+L
Sbjct: 157 PSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLL 216
Query: 538 LNLQGNPLCQAVGILEQLAELLP 560
PL +L + EL P
Sbjct: 217 PEPGLVPLGPHDALLSHVLELQP 239
>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
[Homo sapiens]
Length = 1052
Score = 54.7 bits (130), Expect = 2e-07
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
Query: 441 AEVRVLHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIE 499
+ +R L + H LT L QL+ + LD+S NRLR LP ++ALR L++L S +
Sbjct: 181 SRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELG 240
Query: 500 SLD-GVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGN 543
+L G L L+ L+L NN LQ A+ + RL +LNL N
Sbjct: 241 TLPAGFCELASLESLMLDNNGLQ--ALPAQFSCLQRLKMLNLSSN 283
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 446 LHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-D 502
L ++H LT L + L + L+LSHN+L LP L AL LE L S N + L D
Sbjct: 116 LDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPD 175
Query: 503 GVTNLPRLQELLLCNNRL 520
++ L RL+ L + +N+L
Sbjct: 176 SLSCLSRLRTLDVDHNQL 193
Score = 35.0 bits (79), Expect = 0.18
Identities = 37/97 (38%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 465 VTHLDLSHNRLRTL-PPALAALRCLEVLQASDNAIESLDG-VTNLPRLQELLLCNNRLQQ 522
+T LD+SHNRL L ++ALR L L S N + +L + L L+EL + NRL
Sbjct: 113 LTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRL-- 170
Query: 523 PAVLQPLASC-PRLVLLNLQGNPLCQAVGILEQLAEL 558
A L SC RL L++ N L L QL L
Sbjct: 171 -AHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVAL 206
Score = 32.0 bits (71), Expect = 1.6
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 468 LDLSHNRLRTLPPALAAL-RCLEVLQASDNAIESL--DGVTNLPRLQELLLCNNRLQQPA 524
L L NR LPPA+A L L L S N + +L + V+ L L++L L +N+L PA
Sbjct: 92 LVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQL--PA 149
Query: 525 VLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
+ L + L L++ N L L L+ L
Sbjct: 150 LPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRL 183
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 4e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
Query: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 4e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
Query: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 4e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
Query: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 4e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
Query: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
>gi|194394161 leucine rich repeat containing 57 [Homo sapiens]
Length = 239
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 4/94 (4%)
Query: 461 QLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRL 520
QL + L LS N+L LPP L +LR L+V+ S N I S+ ++ EL L N++
Sbjct: 106 QLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQVIELNLNQNQI 165
Query: 521 QQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQ 554
Q +V ++ CPRL +L L+ N C + +L Q
Sbjct: 166 SQISV--KISCCPRLKILRLEEN--CLELSMLPQ 195
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 6/81 (7%)
Query: 468 LDLSHNRLRTLPPAL-AALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQ-PA 524
+DLS+N++ +LPP L L+ L ++N + L D + NL +L+ L L NN L++ P+
Sbjct: 43 IDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPS 102
Query: 525 VLQPLASCPRLVLLNLQGNPL 545
L++ L L+L GN L
Sbjct: 103 TFGQLSA---LKTLSLSGNQL 120
Score = 32.0 bits (71), Expect = 1.6
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 464 LVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGV-TNLPRLQELLLCNNRLQQ 522
L+ L L++N+L LP + L+ LE L ++N + L L L+ L L N+L
Sbjct: 63 LLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL-- 120
Query: 523 PAVLQPLASCPRLVLLNLQGNPL 545
A+ L S L +++L N +
Sbjct: 121 GALPPQLCSLRHLDVMDLSKNQI 143
>gi|95113664 leucine rich repeat containing 1 [Homo sapiens]
Length = 524
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/203 (31%), Positives = 92/203 (45%), Gaps = 20/203 (9%)
Query: 369 ESCKELQELEPENKWCLLTIILLMRALDPL---LYEKETLQYFQTLKAVDPMRATYLDDL 425
ES ELQ L CL + +++L LY +L+ + L P T L L
Sbjct: 122 ESFPELQNLT-----CLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRL 176
Query: 426 RSKFLLENSVLKMEYAEVRVLHLAHKDLTV----LCHLEQ----LLLVTHLDLSHNRLRT 477
L N + + + +LHL KDL + L L Q L + LD+S NRL
Sbjct: 177 EELDLGNNEIYNLPESIGALLHL--KDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLER 234
Query: 478 LPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRL 535
LP ++ L L L S N +E++ DG+ L +L L + NRL Q P + S L
Sbjct: 235 LPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTEL 294
Query: 536 VLLNLQGNPLCQAVGILEQLAEL 558
VL Q L +++G L++L+ L
Sbjct: 295 VLTENQLLTLPKSIGKLKKLSNL 317
Score = 38.1 bits (87), Expect = 0.022
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 9/101 (8%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCN 517
LE+LLL N+LR LP L L L SDN I+ L + N +L EL +
Sbjct: 38 LEELLL------DANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSR 91
Query: 518 NRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
N + P + + ++ C L + + GNPL + +L L
Sbjct: 92 NEI--PEIPESISFCKALQVADFSGNPLTRLPESFPELQNL 130
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 50.1 bits (118), Expect = 6e-06
Identities = 44/109 (40%), Positives = 56/109 (51%), Gaps = 8/109 (7%)
Query: 443 VRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRTLP-PALAALRCLEVLQASDNAIE 499
VR L L+H L+VL L L + L L HN L+ LP P L+ R L L+ N +
Sbjct: 184 VRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLT 243
Query: 500 SL---DGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
DG+ LP L+ELLL LQ + A CPRL L+L+GN L
Sbjct: 244 YAGEEDGLA-LPGLRELLLDGGALQALGP-RAFAHCPRLHTLDLRGNQL 290
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 5/148 (3%)
Query: 422 LDDLRSKFLLENSVLKMEYAE----VRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRT 477
L +L S FL +N + K++ + + VL + LT + L+ L+ + L LSHN +
Sbjct: 207 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEV 266
Query: 478 LPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVL 537
+ L L +L + N I+ ++ +++L LQE + +N L+ + L L L
Sbjct: 267 IE-GLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLET 325
Query: 538 LNLQGNPLCQAVGILEQLAELLPSVSSV 565
+ L+ NPL + ++ LPSV +
Sbjct: 326 VYLERNPLQKDPQYRRKVMLALPSVRQI 353
Score = 49.3 bits (116), Expect = 9e-06
Identities = 35/117 (29%), Positives = 67/117 (57%), Gaps = 5/117 (4%)
Query: 442 EVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL 501
+V+ L L + + +LE+L + LDL N+++ + L AL LE+L S N + ++
Sbjct: 99 KVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIEN-LEALTELEILDISFNLLRNI 157
Query: 502 DGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
+GV L RL++L L NN++ + ++ L++ +L +L L N + +A+ ++ L L
Sbjct: 158 EGVDKLTRLKKLFLVNNKISK---IENLSNLHQLQMLELGSNRI-RAIENIDTLTNL 210
Score = 37.4 bits (85), Expect = 0.037
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 22/148 (14%)
Query: 439 EYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAI 498
E +R L L + + +LE L + LD+S N LR + + L L+ L +N I
Sbjct: 118 ELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIE-GVDKLTRLKKLFLVNNKI 176
Query: 499 ESLDGVTNLPRLQELLLCNNRLQ-------------------QPAVLQPLASCPRLVLLN 539
++ ++NL +LQ L L +NR++ + LQ L + L +L+
Sbjct: 177 SKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLS 236
Query: 540 LQGNPLCQAVGI--LEQLAELLPSVSSV 565
+Q N L + G+ L L EL S + +
Sbjct: 237 MQSNRLTKIEGLQNLVNLRELYLSHNGI 264
>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
Length = 602
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
Query: 443 VRVLHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL 501
++ L+L H +LT + EQL + LDLS+N L T+P + ++L L L S N ++SL
Sbjct: 153 LKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSL 212
Query: 502 DGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
N + + L CN+ L + + LA L LL L+ N L
Sbjct: 213 PAEINRMKRLKHLDCNSNLLE-TIPPELAGMESLELLYLRRNKL 255
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/173 (26%), Positives = 74/173 (42%), Gaps = 26/173 (15%)
Query: 351 LFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQT 410
L R LS + L +E+ K L+ L+ + L+ + P L E+L+
Sbjct: 199 LVRLNLSSNELKSLPAEINRMKRLKHLDCNSN--------LLETIPPELAGMESLELL-- 248
Query: 411 LKAVDPMRATYLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLC--HLEQLLLVTHL 468
YL + +FL E + ++ LH+ + +L HL+ L + L
Sbjct: 249 ----------YLRRNKLRFLPEFPSCSL----LKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 469 DLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQ 521
DL N+L+++P + LR LE L S+N I SL L+ L L N L+
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGNPLR 347
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 446 LHLAHKDLTVL-CHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGV 504
L+L+ +L L + ++ + HLD + N L T+PP LA + LE+L N + L
Sbjct: 202 LNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEF 261
Query: 505 TNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
+ L+EL + N+++ + L +++L+L+ N L
Sbjct: 262 PSCSLLKELHVGENQIEM-LEAEHLKHLNSILVLDLRDNKL 301
Score = 38.5 bits (88), Expect = 0.017
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 465 VTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQP 523
+T L +S+N+L++L L L L VL DN + SL + L LQ+L + +N+L+
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK-- 141
Query: 524 AVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
+ + + + L L LQ N L EQL+ L
Sbjct: 142 ILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNL 176
Score = 37.4 bits (85), Expect = 0.037
Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 459 LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCN 517
L L +T LD+ N+L +LP A+ L L+ L S N ++ L + +TNL L+ L L +
Sbjct: 101 LRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQH 160
Query: 518 NRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAELL 559
N L + + L L+L N L L+ L+
Sbjct: 161 NEL--TCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLV 200
Score = 36.2 bits (82), Expect = 0.083
Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Query: 456 LCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVT-NLPRLQELL 514
LC L++L T LDL +N L +LP + +L L+ + S N + L V + L+ +L
Sbjct: 468 LCVLQKL---TFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETIL 524
Query: 515 LCNNRLQQPAVLQPLASCPRLVLLNLQGNPLCQ 547
+ NN++ Q + L L+LQ N L Q
Sbjct: 525 ISNNQVGS-VDPQKMKMMENLTTLDLQNNDLLQ 556
Score = 35.4 bits (80), Expect = 0.14
Identities = 40/154 (25%), Positives = 75/154 (48%), Gaps = 11/154 (7%)
Query: 410 TLKAVD--PMRATYLDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTH 467
TLK +D +AT + D + N V + +++ ++ + + +E +V+
Sbjct: 400 TLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKR------MVELKEMVSD 453
Query: 468 LDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQ-PAV 525
+DLS N+L + L L+ L L +N + SL + + +L RLQ + L NR + P V
Sbjct: 454 VDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEV 513
Query: 526 LQPLASCPRLVLLNLQ-GNPLCQAVGILEQLAEL 558
L + + +++ N Q G+ Q + ++E L L
Sbjct: 514 LYRIFTLETILISNNQVGSVDPQKMKMMENLTTL 547
>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
[Homo sapiens]
Length = 639
Score = 49.7 bits (117), Expect = 7e-06
Identities = 46/126 (36%), Positives = 62/126 (49%), Gaps = 8/126 (6%)
Query: 438 MEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNA 497
M Y + L+L +LT L L ++ LDLSHN+L++LP L L VL S N
Sbjct: 68 MPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNR 127
Query: 498 IES--LDGVTNLPRLQELLLCNNRLQ--QPAVLQPLASCPRLVLLNLQGNPLCQ-AVGIL 552
+ S L + L LQEL L N L+ P +L P P+L L+L N L + G+L
Sbjct: 128 LTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP---TPKLEKLSLANNNLTELPAGLL 184
Query: 553 EQLAEL 558
L L
Sbjct: 185 NGLENL 190
>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
Length = 1537
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 44/247 (17%)
Query: 349 EQLFRCE----LSVEKSTV--LQSELESCKELQELE---------PENKWCLLTIILLMR 393
+QLF C+ LS+ + + L + + S L+EL+ PEN C + ++
Sbjct: 63 KQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEA 122
Query: 394 ALDPLLYEKETLQYFQTLKAVDPMRATYLDDLRSKFLLEN--SVLKMEYAEVRVLHLAH- 450
+++P+ K + Q L + YL+D +FL N ++K+ E+R HL
Sbjct: 123 SVNPI--SKLPDGFTQLLN----LTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTL 176
Query: 451 -KDLTVLCHLEQLLL-----------------VTHLDLSHNRLRTLPPALAALRCLEVLQ 492
K + L LE+L L + L + +N L+ LP ++ L+ L L
Sbjct: 177 PKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLD 236
Query: 493 ASDNAIESLD-GVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQAVG 550
S N IE++D ++ L++LLL +N LQQ P + L L + + Q L +G
Sbjct: 237 MSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIG 296
Query: 551 ILEQLAE 557
L L E
Sbjct: 297 NLSLLEE 303
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/119 (31%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 443 VRVLHLAHKDLTVL-CHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL 501
+R L + DL+ L + L+ + LD+S N ++ P + +CL +++AS N I L
Sbjct: 71 LRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKL 130
Query: 502 -DGVTNLPRLQELLLCNNRLQ-QPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
DG T L L +L L + L+ PA L +L +L L+ N L + +LA+L
Sbjct: 131 PDGFTQLLNLTQLYLNDAFLEFLPANFGRLV---KLRILELRENHLKTLPKSMHKLAQL 186
Score = 34.7 bits (78), Expect = 0.24
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 465 VTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDG-VTNLPRLQELLLCNNRLQQP 523
+T L + N+L LP + L LE S N +ESL + L L+ L + N L P
Sbjct: 278 LTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL--P 335
Query: 524 AVLQPLASCPRLVLLNLQGNPL 545
+ + + SC + +++L+ N L
Sbjct: 336 ELPREIGSCKNVTVMSLRSNKL 357
Score = 33.1 bits (74), Expect = 0.70
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 465 VTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLD-GVTNLPRLQELLLCNNRLQQP 523
VT + L N+L LP + ++ L VL SDN +++L T L L L L +N+ +
Sbjct: 347 VTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
Query: 524 AVLQ 527
LQ
Sbjct: 407 IPLQ 410
>gi|116235474 LKB1 interacting protein [Homo sapiens]
Length = 1099
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Query: 443 VRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
+R L+L+H + C L L + HLD+S+NRL +P + L VL N + S
Sbjct: 199 LRFLNLSHNQVQD-CQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRS 257
Query: 501 LDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
L G+ L L+ L L N L+ L PL L L L+GNPL
Sbjct: 258 LHGLEQLRNLRHLDLAYNLLEGHRELSPLWLLAELRKLYLEGNPL 302
>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
Length = 582
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 6/214 (2%)
Query: 351 LFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFQT 410
L R L + + + L C L+EL EN L+ +L L FQ
Sbjct: 286 LSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQL 345
Query: 411 LKAVDPMRATYLDDLRSKFLLENSVLKMEYAEVRVL---HLAHKDLTVL-CHLEQLLLVT 466
P + + + L + N + ++ +VL ++ LT L +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 467 HLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQ-PA 524
L+L+ N+L +P ++ L LEVL S+N ++ L G+ NL +L+EL L N+L+ P
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 525 VLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
+ L +LVL N Q L + +G L L L
Sbjct: 466 EIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHL 499
Score = 43.9 bits (102), Expect = 4e-04
Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Query: 446 LHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DG 503
L+LA LT + + L+ + L LS+N L+ LP L LR L L +N +ESL +
Sbjct: 407 LNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE 466
Query: 504 VTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
+ L LQ+L+L NN+L P + L + L L L + +G LE L EL
Sbjct: 467 IAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEEL 522
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/199 (25%), Positives = 85/199 (42%), Gaps = 24/199 (12%)
Query: 366 SELESCKELQELEPENKWCL----LTIILLMRALDPLLYEKETLQYFQTLKAVDPMRATY 421
S E KEL + EN L +I +L ++ L E Y L+++ P
Sbjct: 86 SNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSL-PAEVGC 144
Query: 422 LDDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPA 481
L +L + L ENS+ + + L+ L + LDL HN+LR +P
Sbjct: 145 LVNLMTLALSENSLTSLPDS-----------------LDNLKKLRMLDLRHNKLREIPSV 187
Query: 482 LAALRCLEVLQASDNAIESLD-GVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLN 539
+ L L L N I +++ + NL +L L + N+++Q PA + L + L + +
Sbjct: 188 VYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAH 247
Query: 540 LQGNPLCQAVGILEQLAEL 558
Q L + +G Q+ L
Sbjct: 248 NQLEHLPKEIGNCTQITNL 266
Score = 37.4 bits (85), Expect = 0.037
Identities = 58/243 (23%), Positives = 87/243 (35%), Gaps = 71/243 (29%)
Query: 348 DEQLFRCELSVEKSTVLQSELESCKELQELE---------PENKWCLLTIILLMRALDPL 398
+E R +LS +L S ++ +L EL P CL+ ++ L + + L
Sbjct: 99 EENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSL 158
Query: 399 LYEKETLQYFQTLKAVD---------PMRATYLDDLRSKFLLENSVLKMEY--------- 440
++L + L+ +D P LD L + +L N + +E
Sbjct: 159 TSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLS 218
Query: 441 -------------AEVR------VLHLAHKDLTVLC-HLEQLLLVTHLDLSHNRLRTLPP 480
AE+ L +AH L L + +T+LDL HN L LP
Sbjct: 219 MLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP- 277
Query: 481 ALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNL 540
D + NL L L L NRL A+ + LA C L LNL
Sbjct: 278 ---------------------DTIGNLSSLSRLGLRYNRLS--AIPRSLAKCSALEELNL 314
Query: 541 QGN 543
+ N
Sbjct: 315 ENN 317
Score = 30.4 bits (67), Expect = 4.5
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 24/105 (22%)
Query: 442 EVRVLHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
+++ L L + LT L + L +THL L N L LP + L LE L +DN
Sbjct: 472 DLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN---- 527
Query: 501 LDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
P L L LA C +L +++++ PL
Sbjct: 528 -------PNLHSLPF------------ELALCSKLSIMSIENCPL 553
>gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens]
Length = 277
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/84 (39%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Query: 465 VTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESL-DGVTNLPRLQELLLCNNRLQQP 523
+T L LSHN+L +PP +A L+ LEVL +N IE L +++L +L+ L L NRL
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLN-- 99
Query: 524 AVLQPLASCPRLVLLNLQGNPLCQ 547
+ + S P L +L+L N L +
Sbjct: 100 TLPRGFGSLPALEVLDLTYNNLSE 123
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/128 (32%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 439 EYAEVRVLHLAHKDLTVL-CHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNA 497
E + VL+ + + L + L + HL+L NRL TLP +L LEVL + N
Sbjct: 61 ELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNN 120
Query: 498 I--ESLDG-VTNLPRLQELLLCNNRLQQPAVLQP-LASCPRLVLLNLQGNPLC---QAVG 550
+ SL G L L+ L L +N + +L P + +L +L+L+ N L + +G
Sbjct: 121 LSENSLPGNFFYLTTLRALYLSDNDFE---ILPPDIGKLTKLQILSLRDNDLISLPKEIG 177
Query: 551 ILEQLAEL 558
L QL EL
Sbjct: 178 ELTQLKEL 185
>gi|157743290 leucine rich repeat containing 30 [Homo sapiens]
Length = 301
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/114 (35%), Positives = 63/114 (55%), Gaps = 11/114 (9%)
Query: 441 AEVRVLHLAHKDLTVLC-HLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIE 499
+EV+ L+L+H L VL + +L + L+L NRL++LP ++ L+CL+VL + N +
Sbjct: 71 SEVQKLNLSHNQLRVLPPEVGKLTRIVVLNLCGNRLKSLPREVSLLQCLKVLFVNMNCLT 130
Query: 500 SLDGVTNLPR-LQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGN-----PLC 546
+ +L R L+ L L +N L Q PA L+ RL LNL N P+C
Sbjct: 131 EVPAELSLCRKLEVLSLSHNCLSQLPACFADLS---RLRKLNLSNNFFAHIPMC 181
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 465 VTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCN-NRLQQP 523
V L+LSHN+LR LPP + L + VL N ++SL +L + ++L N N L +
Sbjct: 73 VQKLNLSHNQLRVLPPEVGKLTRIVVLNLCGNRLKSLPREVSLLQCLKVLFVNMNCLTE- 131
Query: 524 AVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAEL 558
V L+ C +L +L+L N L Q L+ L
Sbjct: 132 -VPAELSLCRKLEVLSLSHNCLSQLPACFADLSRL 165
>gi|193083139 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 47.0 bits (110), Expect = 5e-05
Identities = 41/104 (39%), Positives = 56/104 (53%), Gaps = 9/104 (8%)
Query: 446 LHLAHKDLTVL--CHLEQLLLVTHLDLSHNRLRTLPPA-LAALRCLEVLQASDNAIESLD 502
L L++ ++ ++ LE L + L+LS N LRT L +L CL +L S NA+E+L+
Sbjct: 320 LDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLE 379
Query: 503 -GVTNLPRLQELLLCNNRLQQ--PAVLQPLASCPRLVLLNLQGN 543
G L L+ LLL N L+ P LAS R LNLQGN
Sbjct: 380 LGARALGSLRTLLLQGNALRDLPPYTFANLASLQR---LNLQGN 420
Score = 36.2 bits (82), Expect = 0.083
Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 468 LDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVT--NLPRLQELLLCNNRL 520
LDLSHN L TL AL L L NA+ L T NL LQ L L NR+
Sbjct: 368 LDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 460 EQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNR 519
E L +THL+LS N L + +L+ L VL S N+IE+ + +L + R
Sbjct: 194 EGLPRLTHLNLSRNSLTCISDF--SLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLR 251
Query: 520 LQQPAVLQPLASCPRLVLLNLQGN 543
+ LA+ PRL+ LNL N
Sbjct: 252 ENKLLHFPDLAALPRLIYLNLSNN 275
Score = 30.0 bits (66), Expect = 5.9
Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 20/108 (18%)
Query: 440 YAEVRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNA 497
Y +R L L+ +++ L + L + HL L+HNRL + AL+A
Sbjct: 72 YTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRL-AMATALSA------------- 117
Query: 498 IESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
G+ LPR+ L L N L + + L P L L+L N L
Sbjct: 118 ----GGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSL 161
>gi|5031707 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 47.0 bits (110), Expect = 5e-05
Identities = 41/104 (39%), Positives = 56/104 (53%), Gaps = 9/104 (8%)
Query: 446 LHLAHKDLTVL--CHLEQLLLVTHLDLSHNRLRTLPPA-LAALRCLEVLQASDNAIESLD 502
L L++ ++ ++ LE L + L+LS N LRT L +L CL +L S NA+E+L+
Sbjct: 320 LDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLE 379
Query: 503 -GVTNLPRLQELLLCNNRLQQ--PAVLQPLASCPRLVLLNLQGN 543
G L L+ LLL N L+ P LAS R LNLQGN
Sbjct: 380 LGARALGSLRTLLLQGNALRDLPPYTFANLASLQR---LNLQGN 420
Score = 36.2 bits (82), Expect = 0.083
Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 468 LDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVT--NLPRLQELLLCNNRL 520
LDLSHN L TL AL L L NA+ L T NL LQ L L NR+
Sbjct: 368 LDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 460 EQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNR 519
E L +THL+LS N L + +L+ L VL S N+IE+ + +L + R
Sbjct: 194 EGLPRLTHLNLSRNSLTCISDF--SLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLR 251
Query: 520 LQQPAVLQPLASCPRLVLLNLQGN 543
+ LA+ PRL+ LNL N
Sbjct: 252 ENKLLHFPDLAALPRLIYLNLSNN 275
Score = 30.0 bits (66), Expect = 5.9
Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 20/108 (18%)
Query: 440 YAEVRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNA 497
Y +R L L+ +++ L + L + HL L+HNRL + AL+A
Sbjct: 72 YTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRL-AMATALSA------------- 117
Query: 498 IESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPL 545
G+ LPR+ L L N L + + L P L L+L N L
Sbjct: 118 ----GGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSL 161
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 47.0 bits (110), Expect = 5e-05
Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 15/141 (10%)
Query: 423 DDLRSKFLLENSVLKMEYAEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPAL 482
+D + + LE L + Y + + H+D +L L+ LDLS NRL TLPP L
Sbjct: 446 EDFATTYFLEE--LNLSYNRITSPQV-HRDA-----FRKLRLLRSLDLSGNRLHTLPPGL 497
Query: 483 AALRCLEVLQASDNAIESL--DGVTNLPRLQELLLCNNRLQQPAVLQPLA--SCPRLVLL 538
R + VL+ N + +L + + +L+EL L +NRL+ A L P A L LL
Sbjct: 498 P--RNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRA-LGPRAWVDLAHLQLL 554
Query: 539 NLQGNPLCQAVGILEQLAELL 559
++ GN L + L + E L
Sbjct: 555 DIAGNQLTEIPEGLPESLEYL 575
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,684,915
Number of Sequences: 37866
Number of extensions: 1055109
Number of successful extensions: 3519
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 3070
Number of HSP's gapped (non-prelim): 444
length of query: 567
length of database: 18,247,518
effective HSP length: 108
effective length of query: 459
effective length of database: 14,157,990
effective search space: 6498517410
effective search space used: 6498517410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.