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Search of human proteins with 51944974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51944974 tumor suppressor candidate 1 [Homo sapiens]
(212 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51944974 tumor suppressor candidate 1 [Homo sapiens] 436 e-123
gi|22749429 coiled-coil domain containing 89 [Homo sapiens] 52 5e-07
gi|22749425 spermatid associated [Homo sapiens] 45 5e-05
gi|109452587 family with sequence similarity 98, member B isofor... 45 6e-05
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 44 1e-04
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 44 1e-04
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 43 2e-04
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo... 43 2e-04
gi|239741995 PREDICTED: hypothetical protein XP_002342368 [Homo ... 43 2e-04
gi|12056465 fibrillarin [Homo sapiens] 43 2e-04
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 42 4e-04
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens] 42 5e-04
gi|9506713 nucleolar protein family A, member 1 [Homo sapiens] 42 5e-04
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 41 7e-04
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 41 7e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 41 9e-04
gi|192807292 keratin 24 [Homo sapiens] 40 0.001
gi|153791630 bromodomain and WD repeat domain containing 3 [Homo... 40 0.001
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 40 0.001
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 40 0.001
gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo ... 40 0.002
gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo ... 40 0.002
gi|55956899 keratin 9 [Homo sapiens] 39 0.002
gi|130502140 NEZHA isoform 2 [Homo sapiens] 39 0.002
gi|122937255 NEZHA isoform 1 [Homo sapiens] 39 0.002
gi|119395750 keratin 1 [Homo sapiens] 39 0.003
gi|239754110 PREDICTED: hypothetical protein XP_002345881 [Homo ... 39 0.003
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 39 0.003
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 39 0.003
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 39 0.004
>gi|51944974 tumor suppressor candidate 1 [Homo sapiens]
Length = 212
Score = 436 bits (1120), Expect = e-123
Identities = 212/212 (100%), Positives = 212/212 (100%)
Query: 1 MGPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQ 60
MGPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQ
Sbjct: 1 MGPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQ 60
Query: 61 LEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALRLPGE 120
LEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALRLPGE
Sbjct: 61 LEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALRLPGE 120
Query: 121 GGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRALLQLHLEQR 180
GGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRALLQLHLEQR
Sbjct: 121 GGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRALLQLHLEQR 180
Query: 181 GPRPSGDKEEQPLQEPDSGLRSRDSEPSGPWL 212
GPRPSGDKEEQPLQEPDSGLRSRDSEPSGPWL
Sbjct: 181 GPRPSGDKEEQPLQEPDSGLRSRDSEPSGPWL 212
>gi|22749429 coiled-coil domain containing 89 [Homo sapiens]
Length = 374
Score = 51.6 bits (122), Expect = 5e-07
Identities = 28/58 (48%), Positives = 39/58 (67%), Gaps = 7/58 (12%)
Query: 59 QQLEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALR 116
++LEERF LAA+H +R +DE+ +N +LR+EN +LRL EN SLF QAL+
Sbjct: 120 RKLEERFMTLAANHELMLRFKDEYKSENIKLREENEKLRL-------ENSSLFSQALK 170
>gi|22749425 spermatid associated [Homo sapiens]
Length = 448
Score = 45.1 bits (105), Expect = 5e-05
Identities = 47/146 (32%), Positives = 64/146 (43%), Gaps = 22/146 (15%)
Query: 85 QNARLRQENARLRLENRRLKRENR-----------SLFRQALRLPGEGGNGTPAEARRVP 133
+N LR+EN LR ENR L +EN+ SL R+ R P + A V
Sbjct: 171 ENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVK 230
Query: 134 EE---ASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRAL-LQLHLEQRGPRPSGDKE 189
++ R DS + RAL+ LE+ +A + +A E+ P PS
Sbjct: 231 KDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPS--PH 288
Query: 190 EQP-----LQEPDSGLRSRDSEPSGP 210
E+P LQ+ SGL SR EP GP
Sbjct: 289 EEPCSPGLLQDQGSGLSSRFEEPKGP 314
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 44.7 bits (104), Expect = 6e-05
Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 3 PMWRMR--GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPS----GGGGGVGWRGRADG 56
P W+ R GG R G GG G G G G GR GG GGGGG GW G G
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382
Query: 57 ARQQLEER 64
R + R
Sbjct: 383 GRGGFQGR 390
Score = 35.8 bits (81), Expect = 0.028
Identities = 25/49 (51%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
RGG RG GG G GRG G GR G G P GGGGG G G G
Sbjct: 384 RGGFQGRGDY-GGRGGYGGRG-GYGGR--GYGDPYGGGGGGGGGGGGGG 428
Score = 32.7 bits (73), Expect = 0.23
Identities = 21/52 (40%), Positives = 22/52 (42%), Gaps = 7/52 (13%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGG-------GGGVGWRGR 53
GG RG GG G G G G G GGG GG GG G+ GR
Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGR 402
Score = 31.2 bits (69), Expect = 0.68
Identities = 22/51 (43%), Positives = 23/51 (45%), Gaps = 4/51 (7%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSG-RARG---GGSPSGGGGGVGWRGRAD 55
GG G GG G G G GR G + RG G GG GG G RG D
Sbjct: 362 GGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGD 412
Score = 30.8 bits (68), Expect = 0.89
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 17/68 (25%)
Query: 6 RMRGGATRRGSCCGGDGAADGRGPGRSG-----------------RARGGGSPSGGGGGV 48
R G +R + C + GR P R G R GGG G GGG
Sbjct: 283 RTSSGTSREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGG 342
Query: 49 GWRGRADG 56
G GR G
Sbjct: 343 GGGGRGGG 350
Score = 30.8 bits (68), Expect = 0.89
Identities = 21/52 (40%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARG---GGSPSGGGGGVGWRGRADG 56
RGG G GG G G G G RG G GG GG G RG G
Sbjct: 356 RGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGG 407
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 71 SHLEAIRARDEWDRQNARLRQENA----RLRLENRRLKRENRSLFRQALR---LPGEG-G 122
S E R D W A+ +++ A + RLE +RL+ R L+ + R L EG G
Sbjct: 217 SEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEG 276
Query: 123 NGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRALLQLHLEQRGP 182
P EA R P E R G ED R R RLE E R E+R
Sbjct: 277 QEPPLEAERAPREEQ-QRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRL 335
Query: 183 RPSGDKEEQPLQEPDSG-----LRSRDSEPSGPW 211
EE+ QE + G L+ ++ E + W
Sbjct: 336 EEDARLEERRRQEEEEGRCAEELKRQEEEEAEGW 369
Score = 35.4 bits (80), Expect = 0.036
Identities = 47/165 (28%), Positives = 61/165 (36%), Gaps = 35/165 (21%)
Query: 55 DGARQQLEERFADLAASHLEAIRARDE----------WDRQNARLRQENARLRLENRRLK 104
+ RQ+L E + LEA RA E W+ R R+E RL E
Sbjct: 263 ENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAE----- 317
Query: 105 RENRSLFRQALRLPGEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKL 164
E R L QA E RR+ E+A R R +E+E G R E+
Sbjct: 318 EERRRLQAQA----------QAEERRRLEEDARLEERRR---QEEEEGRCAEELKRQEEE 364
Query: 165 EAMYRRALLQLHLEQRGPRPSGDKEEQPLQEPDSGLRSRDSEPSG 209
EA L Q E +GP + L+E G R + E G
Sbjct: 365 EAEGWEELEQQEAEVQGP-------PEALEETGEGRRGAEEEDLG 402
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 43.5 bits (101), Expect = 1e-04
Identities = 24/54 (44%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 3 PMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
P + GA G+ GG GA D GPG G GGG P GG GG G G G
Sbjct: 123 PSLALMAGAGGAGAAAGGGGAHD--GPGGGGGPGGGGGPGGGPGGGGGGGPGGG 174
Score = 28.9 bits (63), Expect = 3.4
Identities = 15/35 (42%), Positives = 15/35 (42%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSG 43
GG G GG G G GPG G GGG G
Sbjct: 151 GGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGG 185
>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform b [Homo sapiens]
Length = 373
Score = 43.1 bits (100), Expect = 2e-04
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRAD----GARQQLEER 64
G A + GG G A G GP +G GGG GGGG G G ++R
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDR 260
Query: 65 FADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENR 108
F+D L + R E +RQ + +E +RL+ +R +NR
Sbjct: 261 FSD---EQLVTMSVR-ELNRQLRGVSKEEV-IRLKQKRRTLKNR 299
>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform a [Homo sapiens]
Length = 403
Score = 43.1 bits (100), Expect = 2e-04
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRAD----GARQQLEER 64
G A + GG G A G GP +G GGG GGGG G G ++R
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDR 260
Query: 65 FADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENR 108
F+D L + R E +RQ + +E +RL+ +R +NR
Sbjct: 261 FSD---EQLVTMSVR-ELNRQLRGVSKEEV-IRLKQKRRTLKNR 299
>gi|239741995 PREDICTED: hypothetical protein XP_002342368 [Homo
sapiens]
Length = 224
Score = 42.7 bits (99), Expect = 2e-04
Identities = 58/194 (29%), Positives = 73/194 (37%), Gaps = 43/194 (22%)
Query: 20 GDGAADGRGPGRSGRAR-------------GGGSPSGGGGGVGWRGRADGARQQLEERFA 66
G G + G G G AR GG + GGG GW G GAR+ A
Sbjct: 23 GVGKSAGAAAGEEGGARLQATRTWPAGILEGGPQVAARGGGRGWEGGGLGARR------A 76
Query: 67 DLAASHLEAIRARDEWDRQNARLRQENARLRLENRR--LKRENRSLFRQALRLPGEGGNG 124
AA E RAR+ A R NA +R L+ + R R+A GG G
Sbjct: 77 VTAARRGEWGRARESRSAALASPRVSNAPTTPASRNPGLRAQERQSGRRA-----AGGGG 131
Query: 125 TPAEARRVP-------EEASTNRRARDSG-----REDEPGSPRALRA----RLEKLEAMY 168
AE RVP + +RRA +G R+ P P A + L Y
Sbjct: 132 ARAEPPRVPPCRPAGCSGGNRSRRAAGAGPRTTRRKPPPRPPGTAPAAGLRSVHLLRIPY 191
Query: 169 RRALLQLHLEQRGP 182
+ LL +H RGP
Sbjct: 192 KEPLL-VHQNYRGP 204
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 42.7 bits (99), Expect = 2e-04
Identities = 25/47 (53%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 8 RGGATRRGSCCG--GDGAADGRGPGRSGRARGGGSPSGGGGGVGWRG 52
RGG RG G G G GRG G GR RGGG GGGGG G G
Sbjct: 15 RGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG 61
Score = 38.1 bits (87), Expect = 0.006
Identities = 25/58 (43%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 8 RGGATRRGSCCGGDGAADG---RGPGRSGRARGGGSPSGGGGGV---GWRGRADGARQ 59
RGG RG GG G G RG G G GGG GGGG G RGR G ++
Sbjct: 21 RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKR 78
Score = 37.7 bits (86), Expect = 0.007
Identities = 25/62 (40%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 1 MGPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGG------SPSGGGGGVGWRGRA 54
M P + RGG G G GRG GR RGGG GGGGG G GR
Sbjct: 1 MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
Query: 55 DG 56
G
Sbjct: 61 GG 62
Score = 32.7 bits (73), Expect = 0.23
Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 6 RMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLE 62
R RGG R GG G G G GR G G G G G G RG G +E
Sbjct: 34 RGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRG-GKRGNQSGKNVMVE 89
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 42.0 bits (97), Expect = 4e-04
Identities = 19/40 (47%), Positives = 20/40 (50%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGG 47
RGG + G GG G G G G G GGG SGGG G
Sbjct: 476 RGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSG 515
Score = 37.7 bits (86), Expect = 0.007
Identities = 20/55 (36%), Positives = 21/55 (38%)
Query: 11 ATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERF 65
A RG G GA G G G GGG+ GGGG G G L F
Sbjct: 473 AVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNF 527
>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/46 (54%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 9 GGATRRGSCCGGDGAADGRGPG-RSGRARGGGSPSGGGGGVGWRGR 53
GG RG GG G GRG G R GR GGG GG GG G+RGR
Sbjct: 171 GGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGG-GFRGR 215
Score = 35.8 bits (81), Expect = 0.028
Identities = 26/51 (50%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGAR 58
RGG RG GG G GRG GR G RGG GGGGG GR G R
Sbjct: 169 RGGG--RGGRGGGRGGG-GRGGGRGGGFRGG---RGGGGGGFRGGRGGGFR 213
Score = 32.3 bits (72), Expect = 0.30
Identities = 21/46 (45%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 14 RGSCCGGDGAADGRGPGRSGRA--RGGGSPSG-GGGGVGWRGRADG 56
+G GG G G G GR RGGG G GGGG G+RG G
Sbjct: 165 KGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGG 210
Score = 32.0 bits (71), Expect = 0.40
Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 19 GGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
G G G G G G RGGG GG GG G+RG G
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGG-GFRGGRGG 199
Score = 30.4 bits (67), Expect = 1.2
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGG---GGGVGWRGRADG 56
RGG R G GG G RG + GGG GG GGG G GR G
Sbjct: 4 RGGG-RGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGG 54
Score = 30.0 bits (66), Expect = 1.5
Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 27 RGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
R PG G RGGG G GGG G GR G
Sbjct: 160 RPPGEKGPPRGGGR-GGRGGGRGGGGRGGG 188
>gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/46 (54%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 9 GGATRRGSCCGGDGAADGRGPG-RSGRARGGGSPSGGGGGVGWRGR 53
GG RG GG G GRG G R GR GGG GG GG G+RGR
Sbjct: 171 GGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGG-GFRGR 215
Score = 35.8 bits (81), Expect = 0.028
Identities = 26/51 (50%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGAR 58
RGG RG GG G GRG GR G RGG GGGGG GR G R
Sbjct: 169 RGGG--RGGRGGGRGGG-GRGGGRGGGFRGG---RGGGGGGFRGGRGGGFR 213
Score = 32.3 bits (72), Expect = 0.30
Identities = 21/46 (45%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 14 RGSCCGGDGAADGRGPGRSGRA--RGGGSPSG-GGGGVGWRGRADG 56
+G GG G G G GR RGGG G GGGG G+RG G
Sbjct: 165 KGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGG 210
Score = 32.0 bits (71), Expect = 0.40
Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 19 GGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
G G G G G G RGGG GG GG G+RG G
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGG-GFRGGRGG 199
Score = 30.4 bits (67), Expect = 1.2
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGG---GGGVGWRGRADG 56
RGG R G GG G RG + GGG GG GGG G GR G
Sbjct: 4 RGGG-RGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGG 54
Score = 30.0 bits (66), Expect = 1.5
Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 27 RGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
R PG G RGGG G GGG G GR G
Sbjct: 160 RPPGEKGPPRGGGR-GGRGGGRGGGGRGGG 188
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 41.2 bits (95), Expect = 7e-04
Identities = 40/141 (28%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 5 WRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEER 64
W GG G GG G A G G G G GGG GGGGG G RGR G
Sbjct: 9 WGRDGGPRSSGGGYGG-GPAGGHG-GNRGSGGGGG---GGGGGRGGRGRHPG-------- 55
Query: 65 FADLAASHLEAIRARDEWDRQNARLRQENARLRLENRR------------LKRENRSLFR 112
L + A+ + + RQE A + ++ RR K + S +
Sbjct: 56 --HLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQ 113
Query: 113 QALRLPGEGGNGTPAEARRVP 133
+ P + G GT + P
Sbjct: 114 ISWFAPEDHGYGTEVSTKNTP 134
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 41.2 bits (95), Expect = 7e-04
Identities = 40/141 (28%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 5 WRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEER 64
W GG G GG G A G G G G GGG GGGGG G RGR G
Sbjct: 9 WGRDGGPRSSGGGYGG-GPAGGHG-GNRGSGGGGG---GGGGGRGGRGRHPG-------- 55
Query: 65 FADLAASHLEAIRARDEWDRQNARLRQENARLRLENRR------------LKRENRSLFR 112
L + A+ + + RQE A + ++ RR K + S +
Sbjct: 56 --HLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQ 113
Query: 113 QALRLPGEGGNGTPAEARRVP 133
+ P + G GT + P
Sbjct: 114 ISWFAPEDHGYGTEVSTKNTP 134
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 40.8 bits (94), Expect = 9e-04
Identities = 59/209 (28%), Positives = 75/209 (35%), Gaps = 46/209 (22%)
Query: 11 ATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLAA 70
A G C G G+A GR PGR P G GGG G GR +GA +
Sbjct: 3 AAAGGGSCPGPGSARGRFPGR---------PRGAGGGGGRGGRGNGAER----------- 42
Query: 71 SHLEAIRARDEWDRQNARLRQENARLRLEN-RRLKRENRSLFRQALRLPGEG---GNGTP 126
+ R A ++ A LRL RR R R L+ G G G G
Sbjct: 43 VRVALRRGGGATGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWG 102
Query: 127 AEARRVPEEASTNRRARDSG----REDEPGSPRALRARLEKLEAMYRRALLQLHLEQRGP 182
VPEE S++ + + DE +P +LR+ L R P
Sbjct: 103 PSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRG-------------RAP 149
Query: 183 RPSGDKEE-QPLQEPDSGLRSRDSEPSGP 210
R G K + PL P R D P+ P
Sbjct: 150 RGRGRKHKTTPLPPP----RLADVAPTPP 174
Score = 32.3 bits (72), Expect = 0.30
Identities = 37/173 (21%), Positives = 62/173 (35%), Gaps = 39/173 (22%)
Query: 25 DGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLEAIRARDEWDR 84
+G GPG RGG S GG GG RGR G +F A
Sbjct: 270 EGPGPGPGTPRRGGQSSRGGRGG---RGRGRGGGLPFVIKFVSRA--------------- 311
Query: 85 QNARLRQENARLRLENRRLKRENRSLFRQA-LRLPGEGGNGTPAEARRVPEEASTNRRAR 143
+++ L LE+ + + ++ ++ R G G G+P ++ + +
Sbjct: 312 --KKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKK 369
Query: 144 DSGREDEPGSPRALRARLEKLEAMYRRALLQLHLEQRGPRPSGDKEEQPLQEP 196
+ +D+ G + RA E++ P+ +KEE L P
Sbjct: 370 EEEEKDKEGEEKEERAVAEEM------------------MPAAEKEEAKLPPP 404
Score = 27.3 bits (59), Expect = 9.8
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 4/46 (8%)
Query: 8 RGGATRRGSCCGGDGAADGRGPG----RSGRARGGGSPSGGGGGVG 49
RG R GG G GRG G R RGGG+ GG G
Sbjct: 17 RGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPG 62
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 13/86 (15%)
Query: 9 GGATRRGSCCGGDGAADG-----RGPGRSGRARGGGSPSGG--------GGGVGWRGRAD 55
GGA+ G+ GG + G RG G G +R +GG GGGVG G
Sbjct: 78 GGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFS 137
Query: 56 GARQQLEERFADLAASHLEAIRARDE 81
G +Q + D A++L+ +RA +E
Sbjct: 138 GGEKQTMQNLNDRLANYLDKVRALEE 163
>gi|153791630 bromodomain and WD repeat domain containing 3 [Homo
sapiens]
Length = 1802
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 5 WRMRGGATRRGSCCGGDGAADGRGPG---RSGRARGGGSPSGGGGGVGWRGRADGARQQL 61
W+ RG R G + GRG G R R RGGG G G G G RG + GA +
Sbjct: 1665 WKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAK 1724
Query: 62 EERFAD 67
R AD
Sbjct: 1725 RARIAD 1730
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 40.4 bits (93), Expect = 0.001
Identities = 45/161 (27%), Positives = 62/161 (38%), Gaps = 12/161 (7%)
Query: 47 GVGWRGRA-------DGARQQLEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLE 99
G W RA + R QL E+ ++ S E RA E QN RL Q+ A+
Sbjct: 111 GAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQT 170
Query: 100 NRRLKRENRSLFRQALRLPGEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRA 159
+ L+RE ALR + AE R E + S R+D R LR
Sbjct: 171 EQELQRE-----LDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLRE 225
Query: 160 RLEKLEAMYRRALLQLHLEQRGPRPSGDKEEQPLQEPDSGL 200
+EK E + +L L +R R + E+ E L
Sbjct: 226 EVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEAL 266
Score = 31.2 bits (69), Expect = 0.68
Identities = 53/190 (27%), Positives = 69/190 (36%), Gaps = 34/190 (17%)
Query: 32 SGRARGGGSPSGG---------------GGGVGWRGRADGARQ-QLEERFADLAASHLEA 75
SG GG SPSG GGG G D A Q Q +E+ LAA +
Sbjct: 11 SGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKM 70
Query: 76 IRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALRLPGEGGNGTPAEARRVPEE 135
+ R+E R+ +L +A+ RL++EN L R G G EAR V E
Sbjct: 71 LLERNEELRR--QLETLSAQHLEREERLQQENHELRR------GLAARGAEWEARAVELE 122
Query: 136 ASTNRRARDSG--REDEPGSPRALRARLEKLEAMYRRALLQLHLEQRGPRPSGDKEEQPL 193
G R ++ S R L +L R QL + EQ L
Sbjct: 123 GDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQL--------AQASQTEQEL 174
Query: 194 QEPDSGLRSR 203
Q LR +
Sbjct: 175 QRELDALRGQ 184
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/48 (47%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
GG R G GG G+ G+GPG G GGG SGGG G G +DG
Sbjct: 559 GGGQRPG---GGHGSGGGQGPG-DGHGSGGGKNSGGGKGSGSGKGSDG 602
Score = 33.9 bits (76), Expect = 0.10
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 8 RGGATRRGSCCGGDGAA-DGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
RGG G GG+ + DG+G + GG P GG G G +G DG
Sbjct: 530 RGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDG 579
Score = 29.6 bits (65), Expect = 2.0
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 1/45 (2%)
Query: 15 GSCCGGDGAADGRGPGRSGRARGGGSPS-GGGGGVGWRGRADGAR 58
G+ C G+G G G +G+ GG S G G G G G R
Sbjct: 519 GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQR 563
Score = 28.9 bits (63), Expect = 3.4
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 9/58 (15%)
Query: 8 RGGATRRGSCCGGD-------GAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGAR 58
+G + GS GGD G+ +GRG G + G GS S GG G G+R
Sbjct: 475 QGKEDQEGS--GGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSR 530
>gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo
sapiens]
Length = 190
Score = 39.7 bits (91), Expect = 0.002
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 14/155 (9%)
Query: 2 GPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPS----GGGGGVGWRGRADGA 57
G W RGG G G G R+G + G SP+ G G + G
Sbjct: 21 GATWLGRGGGAGPGQSGPGHGQGTATSWARTGESGAGPSPAWRRCAGEASRGRQRARSGP 80
Query: 58 RQQLEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSLFRQALRL 117
+ A L A+ + RA Q +LR+E+AR R + ++ + LRL
Sbjct: 81 PKSPRRPDAQLRAARTQRARA------QTPQLRREDARAGDGWPRREEDDVPPEEKRLRL 134
Query: 118 PGEGGNGTPAEARRVP----EEASTNRRARDSGRE 148
EGG+ P + P EE T G E
Sbjct: 135 LLEGGSAQPEDGEDAPRPGREETGTQTGGDGKGAE 169
Score = 28.5 bits (62), Expect = 4.4
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 9/87 (10%)
Query: 119 GEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRALLQLHLE 178
GE G G RR EAS R R R P SPR A+L A +RA Q
Sbjct: 52 GESGAGPSPAWRRCAGEAS---RGRQRARSGPPKSPRRPDAQLR--AARTQRARAQTPQL 106
Query: 179 QRGPRPSGD----KEEQPLQEPDSGLR 201
+R +GD +EE + + LR
Sbjct: 107 RREDARAGDGWPRREEDDVPPEEKRLR 133
>gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo
sapiens]
Length = 286
Score = 39.7 bits (91), Expect = 0.002
Identities = 31/94 (32%), Positives = 37/94 (39%), Gaps = 16/94 (17%)
Query: 15 GSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLE 74
G GG A G GRS GGG GGGG RGR G R +
Sbjct: 156 GPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGER----------GGPRAQ 205
Query: 75 AIRARDEWDRQNARLRQENARLRLENRRLKRENR 108
A+R R+ + LR R RL+ R +E R
Sbjct: 206 AVR------RRLSALRGRGRRRRLKRLRRAQETR 233
Score = 30.0 bits (66), Expect = 1.5
Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADL 68
GG GG +A G G G G G GS G GGG RA R++L
Sbjct: 160 GGGAEAQFLGGGRSSAGG-GGGGGGGGGGRGSRRGRGGGERGGPRAQAVRRRLSALRGRG 218
Query: 69 AASHLEAIRARDEWDRQNARLRQENARLRLE 99
L+ +R E R A L + A +R E
Sbjct: 219 RRRRLKRLRRAQE-TRGAAALERACASVREE 248
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 39.3 bits (90), Expect = 0.002
Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGR-----SGRARGGGSPSGGGGGVGWRGRADG 56
RG G GG G+ G G G SG + GGGS SGGG G G+ G + G
Sbjct: 487 RGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG 540
Score = 37.7 bits (86), Expect = 0.007
Identities = 21/44 (47%), Positives = 23/44 (52%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRG 52
GG GS G G + G G SG GGGS SGGG G G+ G
Sbjct: 531 GGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGG 574
Score = 36.6 bits (83), Expect = 0.016
Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 19 GGDGAADGRGP--GRSGRARGGGSPSGGGGGVGWRGRADGA 57
GG G + GRG G G GGGS G GGG G RG + G+
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519
Score = 35.4 bits (80), Expect = 0.036
Identities = 22/49 (44%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGA 57
GG GS G G + G G SG GGGS G GGG G RG + G+
Sbjct: 539 GGGHSGGSGGGHSGGSGGNYGGGSGS--GGGSGGGYGGGSGSRGGSGGS 585
Score = 34.3 bits (77), Expect = 0.080
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRG 52
RGG+ GS GG G+ G G G G + GG S GGG G G
Sbjct: 513 RGGSG--GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSG 555
Score = 33.9 bits (76), Expect = 0.10
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSG--GGGGVGWRGRADG 56
GG+ RG G G G G G SG GGGS G GG G G G + G
Sbjct: 508 GGSGSRGGSGGSYGGGSGSG-GGSGGGYGGGSGGGHSGGSGGGHSGGSGG 556
Score = 33.9 bits (76), Expect = 0.10
Identities = 20/42 (47%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSP-SGGGGGVG 49
GG+ RG G G G G G SG + GGG SG GGG G
Sbjct: 574 GGSGSRGGSGGSHGGGSGFG-GESGGSYGGGEEASGSGGGYG 614
Score = 32.7 bits (73), Expect = 0.23
Identities = 17/49 (34%), Positives = 21/49 (42%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGA 57
GG G GG G+ G G G + GG GG GG G + G+
Sbjct: 498 GGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGS 546
Score = 32.3 bits (72), Expect = 0.30
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 9 GGATRRGSCCGGDGAADGRG-PGRSGRARGGGSPSGGGGGVGWRGRADG 56
GG+ G GG G G G G SG GGS GGG G G + G
Sbjct: 522 GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG 570
Score = 31.6 bits (70), Expect = 0.52
Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQ 60
GG GS GG G+ G G G R GGS GG G G G + G ++
Sbjct: 555 GGNYGGGSGSGG-GSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
Score = 30.4 bits (67), Expect = 1.2
Identities = 18/48 (37%), Positives = 21/48 (43%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
GG + G G G G G A GGG S GG G G+ G + G
Sbjct: 74 GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG 121
Score = 28.9 bits (63), Expect = 3.4
Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 20/89 (22%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG------------ 56
GG+ G GG ++ G G G GGG G G G G G G
Sbjct: 92 GGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTA 151
Query: 57 ----ARQQLEERFADLAASHLEAIRARDE 81
Q+L R AS+L+ ++A +E
Sbjct: 152 NEKSTMQELNSRL----ASYLDKVQALEE 176
Score = 27.7 bits (60), Expect = 7.5
Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGS----PSGGGGGVGWRGRADG 56
GG+ G GG G G G SG + GGGS SGG G G G
Sbjct: 560 GGSGSGGGSGGGYGGGSG-SRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG 610
Score = 27.3 bits (59), Expect = 9.8
Identities = 16/39 (41%), Positives = 16/39 (41%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGG 47
GG R S G G R GR G G S GG GG
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
>gi|130502140 NEZHA isoform 2 [Homo sapiens]
Length = 1249
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/98 (25%), Positives = 44/98 (44%)
Query: 112 RQALRLPGEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRA 171
+Q ++ E G G+P PE S+ + E++ + A + R+E + A +R+
Sbjct: 572 KQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQR 631
Query: 172 LLQLHLEQRGPRPSGDKEEQPLQEPDSGLRSRDSEPSG 209
L + Q PR + + E +E DSG P+G
Sbjct: 632 LGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAG 669
Score = 31.2 bits (69), Expect = 0.68
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 25/130 (19%)
Query: 37 GGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLEAIRARDEWDRQNARL------R 90
G GSP+G + ++G E L + + + DE ++ A L R
Sbjct: 860 GDGSPAGAEDSLEEEASSEG------EPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRR 913
Query: 91 QENARLRLENRRLKRENRSLFRQALRLPGEGGNG-----------TPAEARRVPEEASTN 139
E AR R + + +++E R +A RL E G TPA A R P E
Sbjct: 914 AEEARRRKQWQEVEKEQRR--EEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVG 971
Query: 140 RRARDSGRED 149
R D R++
Sbjct: 972 PRKGDFTRQE 981
>gi|122937255 NEZHA isoform 1 [Homo sapiens]
Length = 1276
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/98 (25%), Positives = 44/98 (44%)
Query: 112 RQALRLPGEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRA 171
+Q ++ E G G+P PE S+ + E++ + A + R+E + A +R+
Sbjct: 599 KQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQR 658
Query: 172 LLQLHLEQRGPRPSGDKEEQPLQEPDSGLRSRDSEPSG 209
L + Q PR + + E +E DSG P+G
Sbjct: 659 LGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAG 696
Score = 31.2 bits (69), Expect = 0.68
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 25/130 (19%)
Query: 37 GGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLEAIRARDEWDRQNARL------R 90
G GSP+G + ++G E L + + + DE ++ A L R
Sbjct: 887 GDGSPAGAEDSLEEEASSEG------EPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRR 940
Query: 91 QENARLRLENRRLKRENRSLFRQALRLPGEGGNG-----------TPAEARRVPEEASTN 139
E AR R + + +++E R +A RL E G TPA A R P E
Sbjct: 941 AEEARRRKQWQEVEKEQRR--EEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVG 998
Query: 140 RRARDSGRED 149
R D R++
Sbjct: 999 PRKGDFTRQE 1008
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 38.9 bits (89), Expect = 0.003
Identities = 26/66 (39%), Positives = 27/66 (40%), Gaps = 15/66 (22%)
Query: 6 RMRGGATRRGSCCGGDGAADGRGPGRSGR---------------ARGGGSPSGGGGGVGW 50
R GG R S CGG G + G G G R ARGGG SG GGG G
Sbjct: 37 RRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG 96
Query: 51 RGRADG 56
G G
Sbjct: 97 GGFGGG 102
Score = 34.3 bits (77), Expect = 0.080
Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 2 GPMWRMRGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGA 57
G + GG+ G GG G G G S GGS GGGG G RG G+
Sbjct: 556 GSSYGSGGGSYGSG---GGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGS 608
Score = 33.9 bits (76), Expect = 0.10
Identities = 20/38 (52%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 15 GSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRG 52
GS GG G G G G S GGGS GGGG G RG
Sbjct: 516 GSRGGGGG---GYGSGGSSYGSGGGSYGSGGGGGGGRG 550
Score = 33.5 bits (75), Expect = 0.14
Identities = 19/48 (39%), Positives = 20/48 (41%)
Query: 10 GATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGA 57
G GS GG G G G S GGGS GGGG G G+
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGS 582
Score = 33.1 bits (74), Expect = 0.18
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 10 GATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
G+ GS GG G G G S RG G S GG +G RG + G
Sbjct: 576 GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGS-SGGSIGGRGSSSG 621
Score = 32.7 bits (73), Expect = 0.23
Identities = 18/47 (38%), Positives = 20/47 (42%)
Query: 10 GATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
G + GS G G+ G G GR GG S GGG G G G
Sbjct: 528 GGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG 574
Score = 30.0 bits (66), Expect = 1.5
Identities = 24/78 (30%), Positives = 26/78 (33%), Gaps = 27/78 (34%)
Query: 6 RMRGGATRRGSCCGGDGA---------------------------ADGRGPGRSGRARGG 38
R GG R SC GG G+ GRG G G GG
Sbjct: 38 RSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGG 97
Query: 39 GSPSGGGGGVGWRGRADG 56
G GG GG G+ G G
Sbjct: 98 GFGGGGFGGGGFGGGGIG 115
Score = 30.0 bits (66), Expect = 1.5
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGV---GWRGRADG 56
GG RGS G G++ G G G G GGG G G G+RG + G
Sbjct: 544 GGGGGRGSY-GSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGG 593
Score = 29.6 bits (65), Expect = 2.0
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 9 GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGAR 58
GG GS G G++ G G SG GGGS G G G G G + G R
Sbjct: 570 GGGGGHGSY--GSGSSSGGYRGGSGGG-GGGSSGGRGSGGGSSGGSIGGR 616
Score = 29.3 bits (64), Expect = 2.6
Identities = 17/40 (42%), Positives = 18/40 (45%), Gaps = 3/40 (7%)
Query: 16 SCCGGDGAADGRGPGRSGRARGGGSPSG---GGGGVGWRG 52
S G G G G G G GGG G GGGG+G G
Sbjct: 79 SVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGG 118
Score = 29.3 bits (64), Expect = 2.6
Identities = 15/35 (42%), Positives = 16/35 (45%)
Query: 19 GGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGR 53
GG G G G G + G G S G GG G GR
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGR 549
Score = 28.1 bits (61), Expect = 5.7
Identities = 19/49 (38%), Positives = 19/49 (38%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADG 56
RGG G G G G G G GGG GG GG G G G
Sbjct: 82 RGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFG 130
Score = 28.1 bits (61), Expect = 5.7
Identities = 20/47 (42%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 9 GGATRRGSCCGGDGAADGR--GPGRSGRARGGGSPSGGG-GGVGWRG 52
GG G GG G G G G G GGG GGG GG G+ G
Sbjct: 95 GGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGG 141
Score = 28.1 bits (61), Expect = 5.7
Identities = 14/32 (43%), Positives = 14/32 (43%)
Query: 27 RGPGRSGRARGGGSPSGGGGGVGWRGRADGAR 58
RG G G GG S GGG G G G R
Sbjct: 518 RGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGR 549
Score = 27.7 bits (60), Expect = 7.5
Identities = 18/44 (40%), Positives = 19/44 (43%), Gaps = 2/44 (4%)
Query: 9 GGATRRGSCCGGDGAADGR--GPGRSGRARGGGSPSGGGGGVGW 50
GG G GG G G G G G GGG GGG G G+
Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY 143
Score = 27.7 bits (60), Expect = 7.5
Identities = 12/21 (57%), Positives = 14/21 (66%)
Query: 37 GGGSPSGGGGGVGWRGRADGA 57
GGGS GGGGG G G + G+
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGS 534
Score = 27.3 bits (59), Expect = 9.8
Identities = 20/52 (38%), Positives = 20/52 (38%), Gaps = 3/52 (5%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSG---GGGGVGWRGRADG 56
RG G GG G G G G GGG G GGGG G G G
Sbjct: 86 RGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGG 137
Score = 27.3 bits (59), Expect = 9.8
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
Query: 9 GGATRRGSC--CGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGA 57
GG +R G G G++ G G G G GGG GG G G G + G+
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGG---GGRGSYGSGGSSYGS 561
>gi|239754110 PREDICTED: hypothetical protein XP_002345881 [Homo
sapiens]
Length = 284
Score = 38.9 bits (89), Expect = 0.003
Identities = 28/73 (38%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 19 GGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLEAIRA 78
G G A+ G GRS GGG GGGG RGR G R A L A+R
Sbjct: 158 GAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGERGGPR---AQAVRRRLSALRG 214
Query: 79 RDEWDRQNARLRQ 91
R R+ RLR+
Sbjct: 215 RGR-RRRLKRLRR 226
Score = 31.2 bits (69), Expect = 0.68
Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 7/97 (7%)
Query: 10 GATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLA 69
GA + A DG G G G G S GGGG G G G + +
Sbjct: 140 GAATLPAAAATTTALDGPGAGGGAERGGSGRSSAGGGG-GGGGGGGGRGSRRGRGGGERG 198
Query: 70 ASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRE 106
+A+R R+ + LR R RL+ R +E
Sbjct: 199 GPRAQAVR------RRLSALRGRGRRRRLKRLRRAQE 229
Score = 30.4 bits (67), Expect = 1.2
Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 8 RGGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSG 43
RGG+ R + GG G G G G S R RGGG G
Sbjct: 165 RGGSGRSSAGGGGGGGGGGGGRG-SRRGRGGGERGG 199
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 38.9 bits (89), Expect = 0.003
Identities = 22/44 (50%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 14 RGSCCGGDGAADGRGPGRSG-RARGGGSPSGGGGGVGWRGRADG 56
RGS GG G DGRG G + RA G S G GG G G+A G
Sbjct: 58 RGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASG 101
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 38.9 bits (89), Expect = 0.003
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 19/163 (11%)
Query: 57 ARQQLEERFADLAASHLEAIRARDEWDRQNARLR------QENARLRLENR-----RLKR 105
A+ +LE++ DL S + + R + +R +L QE+ +++ +LK+
Sbjct: 1072 AKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKK 1131
Query: 106 ENRSLFRQALRLPGEGGNGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLE 165
++ L + +LR+ E G + +++ E +AR E+E + RA RAR+EK
Sbjct: 1132 KDSELSQLSLRVEDEQLLGAQMQ-KKIKE-----LQARAEELEEELEAERAARARVEKQR 1185
Query: 166 AMYRRALLQL--HLEQRGPRPSGDKEEQPLQEPDSGLRSRDSE 206
A R L +L LE+ G +G +E +E + G R+ E
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE 1228
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 38.5 bits (88), Expect = 0.004
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 40/185 (21%)
Query: 26 GRGPGRSGRARGGGSPSGGGGGVGWRGRADGARQQLEERFADLAASHLEAIRARDEWDRQ 85
GR PGR G SPS R R GAR + A R R +Q
Sbjct: 121 GRTPGRRGSRSSKRSPSRAS--TPGRIRTHGARPGM-------------ASRVRTPTSQQ 165
Query: 86 NARLRQENARLRLENR-RLKRENRSLFRQALRLPGEGGNGTPAEARRVPEEA-------- 136
+ R R NR R + R+L +++ R PG G G +E P A
Sbjct: 166 KGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 137 -----------STNRRARDSGREDEPG-----SPRALRARLEKLEAMYRRALLQLHLEQR 180
S++R+ + G+ P SP + +R++ R+ Q H + R
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
Query: 181 GPRPS 185
PR S
Sbjct: 286 SPRRS 290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,434,806
Number of Sequences: 37866
Number of extensions: 602571
Number of successful extensions: 9977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 369
Number of HSP's successfully gapped in prelim test: 454
Number of HSP's that attempted gapping in prelim test: 5030
Number of HSP's gapped (non-prelim): 3301
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.