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Search of human proteins with 5174573
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
(1210 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 2420 0.0
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 699 0.0
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens] 545 e-154
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens] 543 e-154
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 331 2e-90
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 103 8e-22
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 100 6e-21
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 97 7e-20
gi|150170670 piccolo isoform 2 [Homo sapiens] 94 6e-19
gi|150378539 piccolo isoform 1 [Homo sapiens] 94 6e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 91 9e-18
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 91 9e-18
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 90 1e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 89 2e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 89 2e-17
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 80 2e-14
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 77 1e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 77 1e-13
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 77 1e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 77 1e-13
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 76 2e-13
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 75 3e-13
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 75 5e-13
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 75 5e-13
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 75 5e-13
gi|148727255 microtubule associated serine/threonine kinase fami... 74 6e-13
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 73 1e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 73 2e-12
gi|55750053 atrophin-1 [Homo sapiens] 72 2e-12
gi|55750041 atrophin-1 [Homo sapiens] 72 2e-12
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 2420 bits (6271), Expect = 0.0
Identities = 1210/1210 (100%), Positives = 1210/1210 (100%)
Query: 1 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM 60
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM
Sbjct: 1 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM 60
Query: 61 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA 120
LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA
Sbjct: 61 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA 120
Query: 121 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR 180
SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
Sbjct: 121 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR 180
Query: 181 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY 240
ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY
Sbjct: 181 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY 240
Query: 241 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ 300
CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ
Sbjct: 241 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ 300
Query: 301 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL 360
DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
Sbjct: 301 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL 360
Query: 361 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS 420
KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS
Sbjct: 361 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS 420
Query: 421 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS 480
SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS
Sbjct: 421 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS 480
Query: 481 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR 540
SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
Sbjct: 481 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR 540
Query: 541 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV 600
HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV
Sbjct: 541 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV 600
Query: 601 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK 660
GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK
Sbjct: 601 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK 660
Query: 661 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR 720
PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
Sbjct: 661 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR 720
Query: 721 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG 780
TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG
Sbjct: 721 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG 780
Query: 781 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS 840
SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS
Sbjct: 781 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS 840
Query: 841 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
Sbjct: 841 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD
Sbjct: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
Query: 961 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS 1020
KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS
Sbjct: 961 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS 1020
Query: 1021 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH 1080
ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH
Sbjct: 1021 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH 1080
Query: 1081 FESSSKVAQAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQN 1140
FESSSKVAQAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQN
Sbjct: 1081 FESSSKVAQAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQN 1140
Query: 1141 MTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGF 1200
MTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGF
Sbjct: 1141 MTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGF 1200
Query: 1201 QQLQELTKTP 1210
QQLQELTKTP
Sbjct: 1201 QQLQELTKTP 1210
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 699 bits (1804), Expect = 0.0
Identities = 482/1231 (39%), Positives = 678/1231 (55%), Gaps = 106/1231 (8%)
Query: 10 DDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYK-TAKGDELSSRIQNMLGNYEEVK 68
+DRN+LR++E+ERRNQE Q ++AFP PLF EPYK T+K D+LSSRIQ+MLGNY+E+K
Sbjct: 4 EDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK 63
Query: 69 EFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVH---HQSIHTPASGPLS 125
+F+ D S +L P +P + +F H HQS GP
Sbjct: 64 DFIG--------DRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGP-- 113
Query: 126 VGNISHNPKMAQPRTEPMPSLH------AKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDR 179
+ + +Q R+ + S H A S +S DR GSS KKG
Sbjct: 114 ----APSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQH 169
Query: 180 RADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKG 239
G + S+P + P V L+ HS HG+ ++SK
Sbjct: 170 ---GSEHSKSRSSSPGK--------PQAVSSLNSSHSRS------------HGNDHHSKE 206
Query: 240 YCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDG 299
+ +KSP+D + ++P + Q +Q+FPP SL SKS +M QKPTAYVRPMDG
Sbjct: 207 HQRSKSPRDPDA---NWDSPSRVPFSSGQHSTQSFPP-SLMSKSNSMLQKPTAYVRPMDG 262
Query: 300 QDQAPSESPELKPLPEDYRQQTF--EKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
Q ES E K E Y Q+ T+LK +KA LTKLK+PSQ ++ + S +V CV+
Sbjct: 263 Q-----ESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVD 317
Query: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQ 417
EILKEMTHSWPPPLTAIHTP EPSKFPFPTK+SQ + T QK+Y+ S SN Q
Sbjct: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKT--SNGHQ 375
Query: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSS--------A 469
+ SML+DDL+LS SEDSD EQ +K + P S P S EP S H+S +
Sbjct: 376 -SKSMLKDDLKLSSSEDSDGEQDCDK----TMPRSTPGSNSEP--SHHNSEGADNSRDDS 428
Query: 470 ESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPP 529
S S S+S S SDSESESSSSDSE NEP ++ +PEPEPP TNKWQLDNWL KV+ P
Sbjct: 429 SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSP 488
Query: 530 EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGK---RSCQ 586
+ P K + T ++++ P ++SS P + G R Q
Sbjct: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPK-ETSSATPGRDSKTIQKGSESGRGRQ 547
Query: 587 KSPAQQEPP-QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKV 645
KSPAQ + QR+TVG KQPKK KA+A R L+ E E P + K
Sbjct: 548 KSPAQSDSTTQRRTVGKKQPKKAEKAAAEE-PRGGLKIESET---PVDLASSMPSSRHKA 603
Query: 646 KTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVP 705
TKG + E K + P++EKKK+KS+ + K+ E D + E +L P
Sbjct: 604 ATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIET--DTSSSDSDESESLPP 661
Query: 706 LTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKI 765
+++ P S +RT +V ++ + R+ P+ + +LLSPL + L+VKI
Sbjct: 662 SSQTPKYPES---NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKI 718
Query: 766 TLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNK 825
L+LL+RIP P K + K E K P +KH+ E + +S K++ K K + + + DN+
Sbjct: 719 DLNLLTRIPGKPYKETEPPKGEKKNVP--EKHTREAQKQ-ASEKVSNKGKRKHKNEDDNR 775
Query: 826 KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP--PVSSSSQKPAKPALK 883
+K +S+ HK SS + S+ S+ + +K++LP P PV S K + K
Sbjct: 776 ASESKKP--KTEDKNSAGHKPSSNRESSKQSA-AKEKDLLPSPAGPVPSKDPKTEHGSRK 832
Query: 884 RSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVP 943
R+ ++ + + ++ S+ SS KQ++ EGK S SS E K + +++ P P
Sbjct: 833 RTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCP-P 891
Query: 944 SLPN-GNSKPGKPQVKFDKQQ--ADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIE 1000
S P +SKP + ++ FD + AD +++EAKK+K A+ ++DR KA YL+AV+SFIE
Sbjct: 892 SAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIE 951
Query: 1001 CGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNM 1060
CG A E +Q SKS + +YSETVDLIK+ M LK++ A +K VLC+RC+S+L +
Sbjct: 952 CGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYL 1011
Query: 1061 AMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIAS--TGTPSPLSPMPSPASSVGSQS 1118
+F+ KK+ A+KYS+TL +H ++S +QAPSP + S G PSP+SP SP +S S
Sbjct: 1012 RLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSS 1071
Query: 1119 SAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLST 1178
A S +SG + TI P I M +SYV +TS+ L A ++W+QAE L+++ KEFFA L
Sbjct: 1072 GASSASASGSSVTI--PQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDK 1129
Query: 1179 NVCTLALNSSLV-DLVHYTRQGFQQLQELTK 1208
+ L N+S++ DLV YTRQG L++ K
Sbjct: 1130 VMGPLIFNASIMTDLVRYTRQGLHWLRQDAK 1160
>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
Length = 1251
Score = 545 bits (1403), Expect = e-154
Identities = 436/1292 (33%), Positives = 624/1292 (48%), Gaps = 182/1292 (14%)
Query: 6 SLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYE 65
S+Y DRN LR +E+ERRNQE Q+ F LF EPYKT KGDELS+RIQN LGNY+
Sbjct: 43 SVYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYD 102
Query: 66 EVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLS 125
E+K+FL+ +S+ L +G PK P +P T V+ H
Sbjct: 103 EMKDFLTDRSNQSHL------VGVPK-PGVPQ-----------TPVNKIDEHF------- 137
Query: 126 VGNISHNPKMAQPRTEPMPS-LHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGD 184
+A R + PS + + + P + + Q + G G+ K G +DG
Sbjct: 138 ---------VADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGW----QKAGHPPSDGQ 184
Query: 185 HCASVTDSAPERELSPLISLPSP-VPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPA 243
A+ S L + P + + QT R + H SS G+C
Sbjct: 185 QRATQQGSL-RTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSS----GHCV- 238
Query: 244 KSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQA 303
Q FPP SL SK +QQKPTAYVRPMDGQDQA
Sbjct: 239 ----------------------------QNFPP-SLASKPSLVQQKPTAYVRPMDGQDQA 269
Query: 304 PSESPELKPLPE------DYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
P ESP+LK E YR K + AKAKL+K +P Q E CVE
Sbjct: 270 PDESPKLKSSSETSVHCTSYRGVPASKPE-PARAKAKLSKFSIPKQGEESRSGETNSCVE 328
Query: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQ 417
EI++EMT W PPL+AI P EP+KFPFP KDSQ VSS N K+ D ++ N
Sbjct: 329 EIIREMT--WLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTS 386
Query: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPP----SSSA---PPSAPQSLPEPVASAHSSSA- 469
TS MLEDDL+LS E+ + +Q ++ S SA P+ S+P S+ SSS+
Sbjct: 387 NTS-MLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSG 445
Query: 470 ESESTSDSDSSS--DSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAA 527
S S+SDS+SSS DSE+ESSSS+SE ++P +PE EP ++NKWQLD WL KV+ P
Sbjct: 446 SSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVN-PHK 504
Query: 528 PP----------EGPRSTEPPRRHPESKGSSDSATSQEHSESK-------DPPPKSSSKA 570
PP E + P + + G E + + P++++KA
Sbjct: 505 PPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKA 564
Query: 571 P-------RAPPEA---------PHPGKRSCQKSPAQQEP-PQRQTVGTKQPKKPVKASA 613
P ++PP A P P + +PA+ P P R++ G K ++ + SA
Sbjct: 565 PGSKGVKQKSPPAAVAVAVSAAAPPP---AVPCAPAENAPAPARRSAGKKPTRRTERTSA 621
Query: 614 RAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHK 673
G+ + E G+ + K + G RA+ E + +V + +
Sbjct: 622 GDGANCH-RPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL 680
Query: 674 SSLPAPSKAL------SGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQA 727
S + SK S + ++E E+ PL+++Q S S ++A
Sbjct: 681 SRIVPKSKEFIETESSSSSSSSDSDLESEQEEY----PLSKAQTVAASASSGNDQRLKEA 736
Query: 728 V---------------------VVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKIT 766
+ +E + +P +LLSPL+D+ +SL VKI
Sbjct: 737 AANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKID 796
Query: 767 LDLLSRIPQ--PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDC-D 823
L LLSRIP+ P G A A H+S+ + + K +KRK + E D +
Sbjct: 797 LTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYRE 856
Query: 824 NKKIRLEKEIKSQSSSSSSS-----HKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQ-KP 877
KK + EK+ S+ ++S+S+ H + + P +++ K P P+S +S+ K
Sbjct: 857 IKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKY 916
Query: 878 AKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
L S R G SASS+K DS + K + ++SE+
Sbjct: 917 TSEDLTSSSRPN---GNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRP 973
Query: 938 NPFPVPSLPNGNSKPGKPQVKFDK--QQADLHMREAKKMKQKAELMTDRVGKAFKYLEAV 995
P NG+ + ++ FD + AD M+EAK+MK KA+ M ++ GKA Y EA
Sbjct: 974 QTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAA 1033
Query: 996 LSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQ 1055
LSFIECG A E SKS Y++YSETV+LI++ M LK+ S A ++K A LC RC
Sbjct: 1034 LSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCL 1093
Query: 1056 SILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIA---STGTPSPLSPMPSPAS 1112
++L MFR K+D A+KYS+ L +F++SSK AQAPSP A STGTPSP+SP PSPAS
Sbjct: 1094 ALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPAS 1153
Query: 1113 SVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEF 1172
SVGSQ S + + + +S P I M +++V+IT+ +L ++D WE A+ L ++N+EF
Sbjct: 1154 SVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREF 1213
Query: 1173 FARLSTNVCTLALNSSLVDLVHYTRQGFQQLQ 1204
F L + + L+SS+ LV Y++QG L+
Sbjct: 1214 FNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLR 1245
>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
Length = 1226
Score = 543 bits (1399), Expect = e-154
Identities = 435/1291 (33%), Positives = 623/1291 (48%), Gaps = 182/1291 (14%)
Query: 7 LYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEE 66
+Y DRN LR +E+ERRNQE Q+ F LF EPYKT KGDELS+RIQN LGNY+E
Sbjct: 19 VYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYDE 78
Query: 67 VKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSV 126
+K+FL+ +S+ L +G PK P +P T V+ H
Sbjct: 79 MKDFLTDRSNQSHL------VGVPK-PGVPQ-----------TPVNKIDEHF-------- 112
Query: 127 GNISHNPKMAQPRTEPMPS-LHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDH 185
+A R + PS + + + P + + Q + G G+ K G +DG
Sbjct: 113 --------VADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGW----QKAGHPPSDGQQ 160
Query: 186 CASVTDSAPERELSPLISLPSP-VPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAK 244
A+ S L + P + + QT R + H SS G+C
Sbjct: 161 RATQQGSL-RTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSS----GHCV-- 213
Query: 245 SPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAP 304
Q FPP SL SK +QQKPTAYVRPMDGQDQAP
Sbjct: 214 ---------------------------QNFPP-SLASKPSLVQQKPTAYVRPMDGQDQAP 245
Query: 305 SESPELKPLPE------DYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEE 358
ESP+LK E YR K + AKAKL+K +P Q E CVEE
Sbjct: 246 DESPKLKSSSETSVHCTSYRGVPASKPE-PARAKAKLSKFSIPKQGEESRSGETNSCVEE 304
Query: 359 ILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQG 418
I++EMT W PPL+AI P EP+KFPFP KDSQ VSS N K+ D ++ N
Sbjct: 305 IIREMT--WLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSN 362
Query: 419 TSSMLEDDLQLSDSEDSDSEQTPEKPP----SSSA---PPSAPQSLPEPVASAHSSSA-E 470
TS MLEDDL+LS E+ + +Q ++ S SA P+ S+P S+ SSS+
Sbjct: 363 TS-MLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGS 421
Query: 471 SESTSDSDSSS--DSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAP 528
S S+SDS+SSS DSE+ESSSS+SE ++P +PE EP ++NKWQLD WL KV+ P P
Sbjct: 422 SSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVN-PHKP 480
Query: 529 P----------EGPRSTEPPRRHPESKGSSDSATSQEHSESK-------DPPPKSSSKAP 571
P E + P + + G E + + P++++KAP
Sbjct: 481 PILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAP 540
Query: 572 -------RAPPEA---------PHPGKRSCQKSPAQQEP-PQRQTVGTKQPKKPVKASAR 614
++PP A P P + +PA+ P P R++ G K ++ + SA
Sbjct: 541 GSKGVKQKSPPAAVAVAVSAAAPPP---AVPCAPAENAPAPARRSAGKKPTRRTERTSAG 597
Query: 615 AGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKS 674
G+ + E G+ + K + G RA+ E + +V + + S
Sbjct: 598 DGANCH-RPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLS 656
Query: 675 SLPAPSKAL------SGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAV 728
+ SK S + ++E E+ PL+++Q S S ++A
Sbjct: 657 RIVPKSKEFIETESSSSSSSSDSDLESEQEEY----PLSKAQTVAASASSGNDQRLKEAA 712
Query: 729 ---------------------VVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL 767
+ +E + +P +LLSPL+D+ +SL VKI L
Sbjct: 713 ANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKIDL 772
Query: 768 DLLSRIPQ--PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDC-DN 824
LLSRIP+ P G A A H+S+ + + K +KRK + E D +
Sbjct: 773 TLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREI 832
Query: 825 KKIRLEKEIKSQSSSSSSS-----HKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQ-KPA 878
KK + EK+ S+ ++S+S+ H + + P +++ K P P+S +S+ K
Sbjct: 833 KKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYT 892
Query: 879 KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTAN 938
L S R G SASS+K DS + K + ++SE+
Sbjct: 893 SEDLTSSSRPN---GNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQ 949
Query: 939 PFPVPSLPNGNSKPGKPQVKFDK--QQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVL 996
P NG+ + ++ FD + AD M+EAK+MK KA+ M ++ GKA Y EA L
Sbjct: 950 TKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAAL 1009
Query: 997 SFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQS 1056
SFIECG A E SKS Y++YSETV+LI++ M LK+ S A ++K A LC RC +
Sbjct: 1010 SFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLA 1069
Query: 1057 ILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIA---STGTPSPLSPMPSPASS 1113
+L MFR K+D A+KYS+ L +F++SSK AQAPSP A STGTPSP+SP PSPASS
Sbjct: 1070 LLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASS 1129
Query: 1114 VGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFF 1173
VGSQ S + + + +S P I M +++V+IT+ +L ++D WE A+ L ++N+EFF
Sbjct: 1130 VGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFF 1189
Query: 1174 ARLSTNVCTLALNSSLVDLVHYTRQGFQQLQ 1204
L + + L+SS+ LV Y++QG L+
Sbjct: 1190 NDLDLLMGPVTLHSSMEHLVQYSQQGLHWLR 1220
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 331 bits (849), Expect = 2e-90
Identities = 300/1012 (29%), Positives = 447/1012 (44%), Gaps = 129/1012 (12%)
Query: 4 QSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTA----KGDELSSRIQN 59
Q Y DR+ L+ RE ERRNQE QE + F LFGEPYK A KGD L++R+QN
Sbjct: 14 QQCHYEQDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEYTNKGDALANRVQN 73
Query: 60 MLGNYEEVKEFLSTKSH-THRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHT 118
LGNY+E+K L+ S+ H + +N + P+ P ++ S P HQ
Sbjct: 74 TLGNYDEMKNLLTNHSNQNHLVGIPKNSV--PQNPNNKNEPSFFPEQKNRIIPPHQDNTH 131
Query: 119 PASG--PLSV---------GNISHNPKMAQPRTEPMPSLHAKSCGPPDS-QHLTQDRLGQ 166
P++ P SV N P+ ++ P L +++ G P+ Q LTQD+
Sbjct: 132 PSAPMPPPSVVILNSTLIHSNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQ--- 188
Query: 167 EGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQG 226
+ +L P+ P + + +++ P +
Sbjct: 189 ---------------------------SQAKLEDFFVYPAEQPQIGEV---EESNPSAKE 218
Query: 227 SSKVHGSSNNS-KGYCPAKSPKDLAVKVHDKETP--QDSLVAPAQPPSQTFPPPSLPSKS 283
S + S ++ K + SP++ V +P SL+AP+ S PP L K+
Sbjct: 219 DSNPNSSGEDAFKEIFQSNSPEESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCKT 278
Query: 284 VAMQQKPTAYVRPMDGQDQAPSESPELKPLPE---DYRQQTFEKTDLKVPAKAKLTKLKM 340
QQKPTAYVRPMDGQDQAP SP LKP E + +F T L A +K K+
Sbjct: 279 SMGQQKPTAYVRPMDGQDQAPDISPTLKPSIEFENSFGNLSFG-TLLDGKPSAASSKTKL 337
Query: 341 PSQSVEQTYS----NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVS 396
P ++ QT ++ CVEEIL+EMTHSWP PLT++HT +E S F P ++SQH++
Sbjct: 338 PKFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLTSMHTAGHSEQSTFSIPGQESQHLT 397
Query: 397 SVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSED--------------SDSEQTPE 442
QK D +++ + S SMLEDDL+LS ED ++ Q E
Sbjct: 398 PGFTLQKWNDPTTRASTKSVS-FKSMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVE 456
Query: 443 KPPSSSAPPSAPQSLPEPVASAHSSSAE-SESTSDSDSSSDSESESSSSDSEENEPLETP 501
K + P + P + P+P + +S S S S+S S SDS++ESS++DSE NE
Sbjct: 457 KAKPRNNPVNPPLATPQPPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVA 516
Query: 502 APEPEPPTTNKWQLDNWLTKVSQP-----AAPPEGPRST---EPPRRHP-ESKGSSDSAT 552
PEPEPP+TNKWQLD WL KV+ E P T PP P E + +
Sbjct: 517 TPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNA 576
Query: 553 SQEHSESKDPPPKS--SSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
SQ +E K+ P S KA P + K K E ++T+G KQPKK K
Sbjct: 577 SQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEK 636
Query: 611 ASARAGSRTSLQGEREPGLLPYGSRDQTS---KDKPKVKTKGRP-RAAASNEPKPAVPPS 666
+ T +P + +++ S D P+ + K + A EP+P +P +
Sbjct: 637 -----NTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRPNIPLA 691
Query: 667 SEKKKHKSS---LPAPSKALSGPEPAKDNVEDR--TPEHFALVPLTESQGPPHSGSGSRT 721
EKKK++ +P + + D+ D+ T + L P S G
Sbjct: 692 PEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICG 751
Query: 722 SGCRQAVVVQEDSRKDRL----------PLPLRDTKLLSPLRDTPPPQSLMVKITLDLLS 771
+ + ++ + L P+P+ T++LSPLRD ++L VKI LDLLS
Sbjct: 752 ASLTLSTLMSSSGSNNNLSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLDLLS 811
Query: 772 RIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKG--EAERDCDNKKIRL 829
R+P + K + K+ K + + + + K++ E KK RL
Sbjct: 812 RVPGHSSLHAAPAKPDHKETATKPKRQTAVTAVEKPAPKGKRKHKPIEVAEKIPEKKQRL 871
Query: 830 EKE----IKSQSSSSSSSHK-ESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKR 884
E+ + S + HK +++ S + K+E L PPP+S + P
Sbjct: 872 EEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLSPLPEDPP------ 925
Query: 885 SRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDT 936
R + G + P + + K +R EGK + + GDT
Sbjct: 926 --RRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCATFKGISVNEGDT 975
Score = 206 bits (523), Expect = 1e-52
Identities = 244/989 (24%), Positives = 403/989 (40%), Gaps = 97/989 (9%)
Query: 254 HDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPL 313
H TP S+ TF S+P + + D +A ++S K +
Sbjct: 366 HSWPTPLTSMHTAGHSEQSTF---SIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSM 422
Query: 314 PEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA 373
ED + + ++ DL+ P K T Q + E++ E K + PPL
Sbjct: 423 LEDDLKLSSDEDDLE-PVKTLTT----------QCTATELYQAVEKAKPRNNPVNPPLAT 471
Query: 374 IHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSM---LEDDLQLS 430
P + S + +S+ S + + T S+++ + T + QL
Sbjct: 472 PQPPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLD 531
Query: 431 DSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSS 490
+ + Q + P SLP P+ + ++ + + E S
Sbjct: 532 KWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPLLSL 591
Query: 491 DSEENEPLETPAPEPEPPTTN--KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSS 548
E+ P P + P T K +L VSQ + P+ E E
Sbjct: 592 IREKARP----RPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFTWPK 647
Query: 549 DSATSQEHSESKD----PPPKSSSKAPR---APPEAPHPG-----KRSCQKSPAQQEPPQ 596
+ TS E + PP+ +KA AP + P P ++ + P + P
Sbjct: 648 PNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRPNIPLAPEKKKYRGPGKIVPKS 707
Query: 597 RQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLP--YGSRDQTSKDKPKVKTKGRPRAA 654
R+ + T S+ + S T + + +LP S T+K K
Sbjct: 708 REFIETD--------SSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTL 759
Query: 655 ASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVED-----------RTPEHFAL 703
S+ S ++ S +P + P +N+++ R P H +L
Sbjct: 760 MSSSGSNNNLSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSL 819
Query: 704 VPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPP-QSLM 762
P H + ++ V++ + K + R K + P Q L
Sbjct: 820 HAAPAK--PDHKETATKPKRQTAVTAVEKPAPKGK-----RKHKPIEVAEKIPEKKQRLE 872
Query: 763 VKITLDLLSRI--PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAER 820
T+ LL P PP K R E+ + EK S L +
Sbjct: 873 EATTICLLPPCISPAPPHKPPNTR--ENNSSRRANRRKEEKLFPPPLSPLPEDPPRRRNV 930
Query: 821 DCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKP 880
+N +K I +S+ K + + K S E P SS++
Sbjct: 931 SGNNGPFGQDKNIAMTGQITSTKPKRT-EGKFCATFKGISVNEGDTPKKASSATITVTNT 989
Query: 881 ALKRSRREAD-----TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGD 935
A+ + A T +A++T + S+I G SS + +S
Sbjct: 990 AIATATVTATAIVTTTVTATATATATTTTTTTTISTITSTITT---GLMDSSHLEMTSWA 1046
Query: 936 TANPFPVPSLPNGNSKPGKPQVKFDKQ--QADLHMREAKKMKQKAELMTDRVGKAFKYLE 993
+P L + ++ +P++ FD AD +M+EAKK+K KA+ + ++ GKA Y +
Sbjct: 1047 A-----LPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVNYAD 1101
Query: 994 AVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMR 1053
A LSF ECG A E + +KS Y++YSETV+L+++ M LK+F+ A +K AVLC R
Sbjct: 1102 AALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLAVLCYR 1161
Query: 1054 CQSILNMAMFRCKKDIAIKYSRTLNKHF-ESSSKVAQAPSPCIAS-TGTPSPLS-PMPSP 1110
C S+L + MF+ KKD A+KYSR+L ++F +++SKVAQ PSP +++ TPSP+S SP
Sbjct: 1162 CLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVSNGKNTPSPVSLNNVSP 1221
Query: 1111 ASSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNK 1170
+++G+ ++ ++ P I +M +S+V ITS+VL ++ W+ A+ LTR+NK
Sbjct: 1222 INAMGNCNN----------GPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRENK 1271
Query: 1171 EFFARLSTNVCTLALNSSLVDLVHYTRQG 1199
EFF L T + L +SS+ +LV Y RQG
Sbjct: 1272 EFFGDLDTLMGPLTQHSSMTNLVRYVRQG 1300
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 103 bits (258), Expect = 8e-22
Identities = 126/600 (21%), Positives = 248/600 (41%), Gaps = 90/600 (15%)
Query: 390 KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPS--- 446
K + + V +++K+ + + Q T + E++ + + E+ E+ E+ +
Sbjct: 439 KSEEKIKVVEKSEKE-TVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 447 ---SSAPPSAPQSLPE-----PVASAHSSSAESESTSDSDSSSDSESES-----SSSDSE 493
+ +PP+ + PE PV S AE++S ++ S +E +S S + E
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 494 ENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATS 553
P E +PE E + ++ +P + + + P S + A S
Sbjct: 558 AKSPPEAKSPEKEEAKSP-----------AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 554 QEHSESKDP-----PPKSSSKAP---RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQP 605
E+K P P K +K+P ++P +A P K + + P + + ++
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 606 KKPVKASARAGSRTSLQGERE---PGLLPYGSRDQTS---KDKPKVKTKGR-PRAAASNE 658
K PVKA A++ + + E P +++ K K VK + + P A S
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 659 PKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTE-SQGPPHSGS 717
+ A P K K +P KA S PE AK ++ ++PE A P E ++ P
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKS-PEKAK-TLDVKSPE--AKTPAKEEARSPADKFP 782
Query: 718 GSRTSGCRQAVV--------VQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
S ++ V ++ED++ +P ++ ++ SP+++ PQ + VK
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE-EVKSPVKEEEKPQEVKVK----- 836
Query: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSS--------KLAKKRKGEAERD 821
+PP +KAE+++ PA K +K S + K+ +K++ E+
Sbjct: 837 -----EPP------KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 822 CDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPA 881
++K ++E + + + + +K + + K E+ P + +++P+KPA
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945
Query: 882 LKR--------SRREADTCGQDPPKSASSTKSNHKD-SSIPKQRRVEGKGSRSSSEHKGS 932
K+ ++ E ++ PK+ + K + K S P + + E SS++ K S
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Score = 95.9 bits (237), Expect = 2e-19
Identities = 135/582 (23%), Positives = 224/582 (38%), Gaps = 76/582 (13%)
Query: 450 PPSAPQSLPE-PVASAHSS-----------SAESESTSDSDSSSDSESESSSSDSEENEP 497
P S P+ LP+ P S H +E E+ + + +++ ++ EE E
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 498 LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHP--ESKGSSDSATSQE 555
E E E + + TK + P E S E + P E S A S E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETK----SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 556 HSESKDP-----PPKSSSKAP---RAPPEAPHPGKRSCQKSPAQQEPPQR-QTVGTKQPK 606
E+K P P K+ S A ++PPEA P K KSPA+ + P++ ++ ++ K
Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA-KSPAEVKSPEKAKSPAKEEAK 593
Query: 607 KPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNE---PKPAV 663
P +A + +++ ++ E + + +K +VK+ + ++ E P+ A
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 664 PPSSEKKKHKSSLPAPSKA-LSGPEPAKDNV--EDRTPEHFALVPLTESQGPPHSGSG-- 718
P E+ K +P KA PE AK V E ++PE A P+ E P
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK-AKSPVKEEAKSPEKAKSPV 712
Query: 719 ---SRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQ 775
+++ ++ V +E ++ P+++ + SP + P ++ TLD+ S +
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKE-EAKSPEKAKSPEKAK----TLDVKSPEAK 767
Query: 776 PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKS 835
P K R DK P K E+ S +K K +A KK ++ +K
Sbjct: 768 TPAK-EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Query: 836 QSSSSSSSHKESSK--------TKPSRPSSQSSKKEMLP----PPPVSSSSQKPAKPALK 883
+ KE K P + SKKE P P P ++PA K
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 884 RSRREA------DTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
S+ EA D P+ + K K+ + PK++ K ++ K
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAK------- 939
Query: 938 NPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAE 979
PS P K P+ K K++ E K + KA+
Sbjct: 940 ----EPSKP-AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK 976
Score = 89.7 bits (221), Expect = 1e-17
Identities = 121/648 (18%), Positives = 251/648 (38%), Gaps = 50/648 (7%)
Query: 284 VAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQ 343
+A+ + AY + ++G++ P LPE + T +KV ++ K+ ++ +
Sbjct: 393 MALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK 452
Query: 344 S--VEQTYSNEVHCVEEIL-------KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQH 394
+ + + E EE+ KE E +K P P +++
Sbjct: 453 ETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP-PAEEAAS 511
Query: 395 VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAP 454
++ + + S + S + + +++ + S +++ + PP + +P
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE 571
Query: 455 QSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEE-NEPLETPAP---EPEPPTT 510
P V S + + ++ + S + + S ++ S EE P E +P E + P
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE 631
Query: 511 NKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKA 570
K + + + A PE +S E K S + E P K+ +K+
Sbjct: 632 VK-SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690
Query: 571 PRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL 630
P +A P K + + P + + ++ K PVK A+ + + E
Sbjct: 691 PE---KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Query: 631 PYGSRDQTSKD----KPKVKT--KGRPRAAASNEPKPAVPPSSEK----KKHKSSLPAPS 680
+ +K P+ KT K R+ A P+ A P E+ +K KS L +
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA 807
Query: 681 KALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLP 740
KA P K+ V+ E P P + + ++DS+K+
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEK--PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE-- 863
Query: 741 LPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQP-PAGKKHSS 799
+P ++ P P+ V+ + P+ +++ +AEDK+ P +K +
Sbjct: 864 ---------APKKEAPKPK---VEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911
Query: 800 EKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQS 859
K +K K++ A+++ D+ K + + K ++ K+ +K + ++ +
Sbjct: 912 AKVEVKEDAK-PKEKTEVAKKEPDDAKAK--EPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 860 SKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQD--PPKSASSTKS 905
K E + S++P+KP +++ + + T +D PP+ A+ K+
Sbjct: 969 PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Score = 77.0 bits (188), Expect = 1e-13
Identities = 105/501 (20%), Positives = 193/501 (38%), Gaps = 48/501 (9%)
Query: 222 PRTQGSSKVHGSSNNSKGYCPAKSPKDLAVK----VHDKETPQDSLVAPAQPPSQTFPPP 277
P + S V +K AKSP+ K V E + A+ P + P
Sbjct: 512 PEKEAKSPV---KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 278 SLPSKSVAMQQKPTAYVRPMDGQDQAPSE--SPE--LKPLPEDYRQQTFEKTDLKVPAKA 333
+KS A + P P + ++P+E SPE P+ E+ + K+ +K AK+
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 334 KLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQ 393
++K P ++ T E E+ P A +P AE P K
Sbjct: 629 P-AEVKSPEKAKSPT-KEEAKSPEKAKSPEKEEAKSPEKA-KSPVKAEAKS---PEKAKS 682
Query: 394 HVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS---DSEQTPEK---PPSS 447
V + ++ ++ + K + S + S ++++ + + S + +TPEK P
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 448 SAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEP 507
A PE + S E+++ + ++ S ++ + S E +++P P
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP 802
Query: 508 PTTNKWQLDNWLTKVSQPAAP------PEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561
+ + + K + +P P+ + EPP++ E K + T ++ K+
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862
Query: 562 PPPKSSSKAPRAPPEAPHPGKRSCQKSPAQ---QEPPQRQTVGTKQPKKPVKASARAGSR 618
PK + P+ E P ++S + +E ++ V T + + P K + ++
Sbjct: 863 EAPKKEAPKPKV-EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 619 TSLQGE---REPGLLPYGSRDQTSKD--KPKVKTKGRPRAAASNEPKPAVPPSSEKKKHK 673
+ E +EP D +K+ KP K + P + E K P EK K +
Sbjct: 922 PKEKTEVAKKEPD-------DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP--EEKPKTE 972
Query: 674 SSLPAPSKALSGPEPAKDNVE 694
+ K LS EP+K E
Sbjct: 973 AKAKEDDKTLS-KEPSKPKAE 992
Score = 76.3 bits (186), Expect = 2e-13
Identities = 121/586 (20%), Positives = 210/586 (35%), Gaps = 71/586 (12%)
Query: 244 KSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQA 303
KSP +KE + + A+ P++ P +KS A + P P + ++
Sbjct: 502 KSPPAEEAASPEKEA-KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560
Query: 304 PSESPELKPLPEDYRQQTFEKTDLKVPAKAKL-TKLKMPSQSVEQTYSNEVHCVEEILKE 362
P E+ PE +++ ++K P KAK K + S + ++ V+E K
Sbjct: 561 PPEAKS----PE--KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 363 MTHSWPPPLTAIHTPSTAE-PSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSS 421
+ P +P+ + P K PTK+ ++ ++ + K + S + S
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE------AKSPEKAKSPEKEEAKSPEKAKS 668
Query: 422 MLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSS 481
++ + + + S + + P + +P PE S A+S + S
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 482 DSES-ESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR 540
++++ E + S +E A PE T L S A P + P +
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKT--------LDVKSPEAKTPAKEEARSPADK 780
Query: 541 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV 600
PE K S + E P K +KAP E P K+ KSP ++E ++
Sbjct: 781 FPE-KAKSPVKEEVKSPEKAKSPLKEDAKAPEK--EIP---KKEEVKSPVKEEEKPQEVK 834
Query: 601 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK 660
+ PKK + A A +T + + + P + KPKV+ K P E K
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAP-----KKEAPKPKVEEKKEPAVEKPKESK 889
Query: 661 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNV-EDRTPEHFALVPLTESQGPPHSGSGS 719
V E+ + K +P P K PAK V ED P+ V E + S
Sbjct: 890 --VEAKKEEAEDKKKVPTPEKEA----PAKVEVKEDAKPKEKTEVAKKEPDDAK-AKEPS 942
Query: 720 RTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGK 779
+ + ++A ++D+++++ P P+ K
Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKP----------------------------EEKPKTEAK 974
Query: 780 GSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNK 825
K K+P K +EK SS K ++ K
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 62.8 bits (151), Expect = 2e-09
Identities = 92/461 (19%), Positives = 161/461 (34%), Gaps = 51/461 (11%)
Query: 193 APERELSPLIS-LPSPVPPLSPIHSNQQTLPRTQGSSKVHG-SSNNSKGYCPAKSPKDLA 250
+PE+ SP+ SP SP+ ++ + K + +K AKSP+
Sbjct: 600 SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659
Query: 251 VKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPEL 310
K +K + + A A+ P + P +KS + P +++A S
Sbjct: 660 AKSPEKA--KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV--------KEEAKSPEKAK 709
Query: 311 KPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPP 370
P+ E+ + K+ +K AK T K S E+ S E E K + P
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAK---TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766
Query: 371 LTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLS 430
T + + KFP K V ++ ++ + K + + + E+
Sbjct: 767 KTPAKEEARSPADKFPEKAKSP--VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 431 DSEDSDSEQTPEKPPSSSAPPSAP---------QSLPEPVASAHSSSAESESTSDSDSSS 481
E+ E ++PP + AP S E + + E +
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 482 DSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRH 541
ES+ + E + + P PE E P +V + A P E TE ++
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAK---------VEVKEDAKPKE---KTEVAKKE 932
Query: 542 PESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVG 601
P D A ++E S+ P + AP K+ +K + + +
Sbjct: 933 P------DDAKAKEPSK----PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982
Query: 602 TKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDK 642
+K+P KP A S T + + P + D+ +K K
Sbjct: 983 SKEPSKPKAEKAEKSSSTDQKDSKPP---EKATEDKAAKGK 1020
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 100 bits (250), Expect = 6e-21
Identities = 136/582 (23%), Positives = 229/582 (39%), Gaps = 110/582 (18%)
Query: 430 SDSEDS--DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSS-SAESESTSDSDSSSDSESE 486
SDSEDS + E+ P +A P+ LP A+A +S S+ SE +SD D D + +
Sbjct: 85 SDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQ 144
Query: 487 -------------------SSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAA 527
+ SSDS+ + + E EPP K ++ +T +Q A
Sbjct: 145 PVQKGVKPQAKAAKAPPKKAKSSDSDSDS-----SSEDEPPKNQKPKITP-VTVKAQTKA 198
Query: 528 PPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQK 587
PP+ R+ + K +S S++S S S D + ++ P+
Sbjct: 199 PPKPARAAP---KIANGKAASSSSSSSSSSSSDDSEEEKAAATPK--------------- 240
Query: 588 SPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647
+ P++Q V K PVKA+ ++S + S D+ + K +K
Sbjct: 241 ----KTVPKKQVVA----KAPVKAATTPTRKSSSSED--------SSSDEEEEQKKPMKN 284
Query: 648 KGRPRAAASNEPKPAVPPSSE-------KKKHKSSLPAPSKALSGPEPAKDNVEDRTPEH 700
K P S+ P P+ PP + KK + P S S E + E++ P
Sbjct: 285 KPGP---YSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT 341
Query: 701 FALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQS 760
A+V ++ PP + +S + + S D P T S + +S
Sbjct: 342 KAVVSKATTKPPPAKKAAESSSDSSDS----DSSEDDEAPSKPAGTTKNSSNKPAVTTKS 397
Query: 761 LMVKITLDLLSRIPQPPGKGSR--QRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEA 818
VK + QP G G + RKA+ SSE+ SS S + KK
Sbjct: 398 PAVKPA----AAPKQPVGGGQKLLTRKADSS--------SSEEESSSSEEEKTKKMVATT 445
Query: 819 ERDCDNK-KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKP 877
+ K + L + Q S SSS +SS ++ ++SK + P + P
Sbjct: 446 KPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE--EEEEKTSKSAVKKKPQKVAGGAAP 503
Query: 878 AKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
+KPA + K+ SS S+ DSS ++ +++GKGS K A
Sbjct: 504 SKPASAKK-----------GKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPK------A 546
Query: 938 NPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAE 979
N + NG + + + +K++A + + ++ +K++ +
Sbjct: 547 NGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQ 588
Score = 83.2 bits (204), Expect = 1e-15
Identities = 106/459 (23%), Positives = 186/459 (40%), Gaps = 70/459 (15%)
Query: 229 KVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQ 288
K S ++S + PK+ K+ TP PP P + + A
Sbjct: 163 KAKSSDSDSDSSSEDEPPKNQKPKI----TPVTVKAQTKAPPKPARAAPKIANGKAASSS 218
Query: 289 KPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQT 348
++ D ++ + + K +P+ ++ K P KA T + S S E +
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPK-------KQVVAKAPVKAATTPTRKSSSS-EDS 270
Query: 349 YSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTS 408
S+E EE K+ + P P +++ PS P K + +Q + Q+ ++S
Sbjct: 271 SSDE----EEEQKKPMKNKPGPYSSVPPPSAPPPKK----SLGTQPPKKAVEKQQPVESS 322
Query: 409 SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSS 468
+ SD DS SE+ +KPP + A S + P P A SS
Sbjct: 323 EDS------------------SDESDSSSEEE-KKPP-TKAVVSKATTKPPPAKKAAESS 362
Query: 469 AESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAP 528
++S SDSDSS D E+ S + + +N +P T K + +PAA
Sbjct: 363 SDS---SDSDSSEDDEAPSKPAGTTKNS-------SNKPAVTTK-------SPAVKPAAA 405
Query: 529 PEGP--RSTEPPRRHPESKGSSDSATSQEHSESK----DPPPKSSSKAPRAPP--EAPHP 580
P+ P + R +S S + ++S E ++K PK+++KA + P +AP
Sbjct: 406 PKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQG 465
Query: 581 GKRSCQKSPA----QQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRD 636
+ S S + ++E ++ K+P+K +A + ++ +G+ E S D
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESS-NSSSSDD 524
Query: 637 QTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSS 675
+ +++ K+K KG PR A + + K K+S
Sbjct: 525 SSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563
Score = 60.1 bits (144), Expect = 1e-08
Identities = 110/511 (21%), Positives = 188/511 (36%), Gaps = 70/511 (13%)
Query: 665 PSSEKKKHKSSLPAPSKALSGPEPAKDNVED--RTPEHFALVPLTESQGPPHSGSGSRTS 722
P ++K K K+S S E + + E+ P A VP PP + +
Sbjct: 73 PVAKKAKKKASS-------SDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASE 125
Query: 723 GCRQAVVVQEDSRKDRLPLPL-RDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGS 781
+D +D+ P+ + K + PP ++ D S P +
Sbjct: 126 SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKP 185
Query: 782 RQR----KAEDKQPP----AGKKHSSEKRSSDSSSKLAKKRKGEAERD---CDNKKIRLE 830
+ KA+ K PP A K ++ K +S SSS + ++E + KK +
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 831 KEI--------------KSQSSSSSSSHKESSKTKP--SRPSSQSS-KKEMLPPPPVSSS 873
K++ KS SS SSS +E + KP ++P SS PPP S
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 874 SQKPAKPALKRSRREADTCGQDPPKSASSTKSN-------HKDSSIPKQRRVEGKGSRSS 926
+Q P K K+ E+ D S+S + K ++ P + + S S
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS 365
Query: 927 SEHKGSSGDTANPFPVPSLPNGNSKPG----KPQVK---FDKQQA----DLHMREAKKMK 975
S+ S D A P + N ++KP P VK KQ L R+A
Sbjct: 366 SDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSS 425
Query: 976 QKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSF 1035
+ E + K K +AT ++K+A S+ ++ S S
Sbjct: 426 SEEESSSSEEEKTKKM-----------VATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 1036 SDATAPTQEKIF-AVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPC 1094
S ++ +EK + + + Q + A K + K + + + SS ++
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGA--APSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Query: 1095 IASTGTPSPLSPMPSPASSVGSQSSAGSVGS 1125
+ G+P P +P + S++ +Q+ + S
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563
Score = 57.0 bits (136), Expect = 1e-07
Identities = 124/582 (21%), Positives = 190/582 (32%), Gaps = 140/582 (24%)
Query: 567 SSKAPRAPPEAPHPGKRSCQKSPAQ-------------QEPPQRQT------VGTKQPKK 607
S+K P +A P + +K + Q PP ++ VG K
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKA 119
Query: 608 PVKASARAGSRTSLQGERE---------PGLLPY---------------GSRDQTSKDKP 643
KAS + S S + E G+ P D +S+D+P
Sbjct: 120 AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP 179
Query: 644 KVKTKGR-----PRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTP 698
K + +A PKPA +S + S + S + +++ TP
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239
Query: 699 EH-------FALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSP 751
+ A P+ + P S S S + +E+ +K P P
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDE----EEEQKKPMKNKP-------GP 288
Query: 752 LRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLA 811
PPP + K +L QPP +KA +KQ P S SDSSS+
Sbjct: 289 YSSVPPPSAPPPKKSLG-----TQPP------KKAVEKQQPVESSEDSSD-ESDSSSEEE 336
Query: 812 KKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVS 871
KK +A K K+ SS SS S PS+P+ + P
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTK 396
Query: 872 SSSQKPAKP-------ALKRSRREADTCGQDPPKSASSTKSNHK-------------DSS 911
S + KPA K R+AD+ + S+S + K S
Sbjct: 397 SPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALS 456
Query: 912 IPKQRRVEGKGSRSSSEHKGSSGDTANPF---------------PVPSLPNGNSKPGKPQ 956
+P ++ +G SS SS + PS P ++K GK +
Sbjct: 457 LPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP-ASAKKGKAE 515
Query: 957 VKFDKQQADLHMREAKKMKQK------------AELMTDRVGKAFKYLEAVLSFIECGIA 1004
D E +K+K K +T + GKA K
Sbjct: 516 SSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAK-------------N 562
Query: 1005 TESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKI 1046
+E E + K A V S++ L K + ++ +A P +KI
Sbjct: 563 SEEEEEEKKKAAVVVSKSGSLKKRKQN-EAAKEAETPQAKKI 603
Score = 53.1 bits (126), Expect = 2e-06
Identities = 94/476 (19%), Positives = 160/476 (33%), Gaps = 56/476 (11%)
Query: 133 PKMAQPRTEPMPSLHAKSCGPPD----SQHLTQDRLGQEGFGSSHHKKGDRRADGDHCAS 188
PK +P+ P+ ++ A++ PP + + + SS D + A+
Sbjct: 180 PKNQKPKITPV-TVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAAT 238
Query: 189 VTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKV--------HGSSNNSKGY 240
+ P++++ + + P S++ + + K + S
Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP 298
Query: 241 CPAKS-----PKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVR 295
P KS PK K E+ +DS + PP+ S A + P A
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA 358
Query: 296 PMDGQDQAPSESPE-----LKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMP--------- 341
D + S+S E KP K PA K P
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 342 -----SQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA---IHTPSTAEPSKFPFPTKDSQ 393
S S E++ S+E EE K+M + P TA + P+ P + DS
Sbjct: 419 RKADSSSSEEESSSSE----EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 394 HVSSVTQNQKQYDTSSKTHSNSQQGTSSMLE---------DDLQLSDSEDSDSEQTPEKP 444
SS + +K ++ K G ++ + + S S+DS E+ +
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 445 PSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPE 504
S P AP++ +A + A S + + + S S S + A E
Sbjct: 535 GKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKE 594
Query: 505 PEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESK 560
E P K +L T + P R++ P RR E + DS + ++K
Sbjct: 595 AETPQAKKIKLQ---TPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAK 647
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 97.4 bits (241), Expect = 7e-20
Identities = 170/801 (21%), Positives = 287/801 (35%), Gaps = 124/801 (15%)
Query: 157 QHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPL---ISLPSPVPPLSP 213
+ + Q ++ QE S + D+ + ER SP PSP SP
Sbjct: 129 EEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSP 188
Query: 214 IHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQT 273
+ ++ R+ S H + + S P K K TP+
Sbjct: 189 VRRERK---RSHSRSPRHRTKSRSPSPAPEKKEK----------TPE------------- 222
Query: 274 FPPPSLPSKSVAMQQKP-TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAK 332
P PS+ K ++Q+ T+ + + + P E E P +++ EKT + ++
Sbjct: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIP-EPKEPSPEKNSKKEKEKEKTRPRSRSR 281
Query: 333 AKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPP---------PLTAIHTPSTAEPS 383
+K ++ + S+S T H + + S+ P P TP P
Sbjct: 282 SK-SRSRTRSRSPSHTRPRRRH------RSRSRSYSPRRRPSPRRRPSPRRRTP----PR 330
Query: 384 KFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEK 443
+ P P + + S V + ++ ++S + S+S +S + S +T
Sbjct: 331 RMPPPPRHRRSRSPVRRRRRS--SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388
Query: 444 PPSSSAP-----PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPL 498
PS+S P PS P + P + + + + S S + + + E
Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448
Query: 499 ETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSE 558
E+P+P P+P + + K + AA + + R++ +S S S++S E
Sbjct: 449 ESPSPAPKPRKVELSESEE--DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506
Query: 559 SKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSR 618
P +S K H RS SP ++ Q++T P R+ S
Sbjct: 507 ----PKRSHVKNGEVGRRRRHSPSRSASPSPRKR---QKET-------SPRGRRRRSPSP 552
Query: 619 TSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPP-------SSEKKK 671
+ R P P R +T P+ +T P S P+ PP S K+
Sbjct: 553 PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR 612
Query: 672 HKSSLPAPSKALSGPEPA-KDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVV 730
+S P P K + P P K V P P+T+ + P S +S R+
Sbjct: 613 RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP------SLSSKHRKGSSP 666
Query: 731 QEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQ 790
+R+ R P P + R +P P+ R PQ R+
Sbjct: 667 SRSTREARSPQPNK--------RHSPSPRP-----------RAPQTSSSPPPVRR----- 702
Query: 791 PPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKT 850
G S ++R S S S +R R + KKI+ K+ S S S + SS
Sbjct: 703 ---GASSSPQRRQSPSPSTRPIRR---VSRTPEPKKIK-----KAASPSPQSVRRVSSSR 751
Query: 851 KPSRPSSQSSKKEMLPPPPVSSSSQKPA-KPALKRSRREADTCGQDPPKSASSTKSNHKD 909
S ++KK PP PV S S PA+ + ++ T PP+++ K
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK 811
Query: 910 SSIPKQRRVEGKGSRSSSEHK 930
++ + K + +HK
Sbjct: 812 KKKKDKKHKKDKKHKKHKKHK 832
Score = 89.0 bits (219), Expect = 3e-17
Identities = 152/653 (23%), Positives = 233/653 (35%), Gaps = 120/653 (18%)
Query: 361 KEMTHSWPPPLTAIHTPSTAE------------PSKFPFPTKDSQHVSSVTQNQKQYDTS 408
KE T P P + PS E P P P + S +S + +K+
Sbjct: 217 KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP 276
Query: 409 -SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQ-TPEKPPSSSAPPSA-----PQSLPEPV 461
S++ S S+ T S + S S +P + PS PS P+ +P P
Sbjct: 277 RSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP 336
Query: 462 ASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTK 521
S S S S S S S SSSS S + P + P PP + +
Sbjct: 337 RHRRSRSPVRRRRRSSASLSGSSSSSSSSRSR-SPPKKPPKRTSSPPRKTR--------R 387
Query: 522 VSQPAAPPE-----GPRSTEPPR-RHPESKGSSDSATSQEHSESKDPPPKSSSKAPR--- 572
+S A+PP P +T PP+ RH + S+ S S P ++S K +
Sbjct: 388 LSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS---PGRTSGKVTKHKG 444
Query: 573 -----APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKK----PVKASARAGSRTSLQG 623
+P AP P K +S + +Q ++ ++S+ +GS +S +
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
Query: 624 EREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEK-KKHKSSLPAPSKA 682
ER R + + + P +AS P+ +S + ++ +S P P++
Sbjct: 505 ERP-------KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557
Query: 683 LSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLP 742
P PA RTP P + P S R + +Q R P P
Sbjct: 558 RRSPSPAPPPRRRRTP-----TPPPRRRTPSPPPRRRSPSPRRYSPPIQR--RYSPSPPP 610
Query: 743 LRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKR 802
R T SP PPP P PP K R+ PP + KR
Sbjct: 611 KRRTA--SP----PPPPKRRAS---------PSPPPK----RRVSHSPPPKQRSSPVTKR 651
Query: 803 SSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKK 862
S S S +K RKG SS S S +E+ +P++ S S +
Sbjct: 652 RSPSLS--SKHRKG---------------------SSPSRSTREARSPQPNKRHSPSPR- 687
Query: 863 EMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKG 922
P P +SSS P RR A + Q + ST+ + S P+ ++++
Sbjct: 688 ---PRAPQTSSSPPPV-------RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Query: 923 SRSSSEHKGSSGD---TANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAK 972
S S + S + +P P P P + Q + +++AK
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK 790
Score = 65.9 bits (159), Expect = 2e-10
Identities = 115/490 (23%), Positives = 167/490 (34%), Gaps = 100/490 (20%)
Query: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKS--- 588
PR P R + S S + S S P P+ K P P + + S Q++
Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 589 ------------PAQQEP-PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSR 635
P +EP P++ + K+ +K S S R P
Sbjct: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP-------- 293
Query: 636 DQTSKDKPKVKTKGRPRA-AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVE 694
S +P+ + + R R+ + P P PS ++ +P P + P V
Sbjct: 294 ---SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP----VR 346
Query: 695 DRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRD 754
R +L SGS S +S R ++ + R P R T+ LSP
Sbjct: 347 RRRRSSASL-----------SGSSSSSSSSRSRSPPKKPPK--RTSSPPRKTRRLSPSAS 393
Query: 755 TP-------PPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPP---AGK--KH-SSEK 801
P PP + K +R P + +R RK+ P +GK KH +EK
Sbjct: 394 PPRRRHRPSPPATPPPK------TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK 447
Query: 802 RSSDS-SSKLAKKRKGEAERDCDNKKI------------RLEKEIKSQSSSSSSSHKESS 848
R S S + K K E+E D K R ++ S S SSSSS E
Sbjct: 448 RESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP 507
Query: 849 KT--------------KPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADT--- 891
K PSR +S S +K P + P+ P +R R +
Sbjct: 508 KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPP 567
Query: 892 ----CGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPN 947
PP+ + + + S P RR R S TA+P P P
Sbjct: 568 RRRRTPTPPPRRRTPSPPPRRRS--PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA 625
Query: 948 GNSKPGKPQV 957
S P K +V
Sbjct: 626 SPSPPPKRRV 635
Score = 65.1 bits (157), Expect = 4e-10
Identities = 171/796 (21%), Positives = 258/796 (32%), Gaps = 182/796 (22%)
Query: 19 EKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTH 78
+K++R++E EKE+ EK P + R + + + S + T
Sbjct: 150 DKDKRDKE---EKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK 206
Query: 79 RLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQP 138
S K K P +P+ + S + T S L V P+ +P
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA-------TSTSDILKVPKPEPIPEPKEP 259
Query: 139 RTEPMPSLHA-KSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDS-APER 196
E K P S+ ++ R SH + R S +P R
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319
Query: 197 ELSPLISLPSPVPPLSPIH--SNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVH 254
SP P P P H S R + S+ + GSS++S ++SP
Sbjct: 320 RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS-SRSRSP-------- 370
Query: 255 DKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP 314
P +PP +T PP + P RP SP P P
Sbjct: 371 -----------PKKPPKRTSSPPRKTRRLSPSASPPRRRHRP----------SPPATPPP 409
Query: 315 EDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAI 374
+ T P ++ T+ S S +T S +V + K + S P +
Sbjct: 410 KTRHSPT--------PQQSNRTRKSRVSVSPGRT-SGKVTKHKGTEKRESPSPAPKPRKV 460
Query: 375 HTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL------- 427
+ E DS Q ++QY ++ S+S G+SS ED+
Sbjct: 461 ELSESEEDKGGKMAAADS------VQQRRQYRRQNQ-QSSSDSGSSSSSEDERPKRSHVK 513
Query: 428 -----------------------QLSDSEDSDSEQTPEKPPS------SSAPPSAPQSLP 458
Q S ++P PP+ S APP + P
Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP 573
Query: 459 EPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW 518
P + S S S + S S P A P PP
Sbjct: 574 TPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP--PKRRTASPPPPPKRRASPSPPP 631
Query: 519 LTKVSQPAAPPEGPRSTEPPRRHPE--SKGSSDSATSQEHSESKDPPPK---SSSKAPRA 573
+VS + PP+ S RR P SK S+ S+ E++ P P S S PRA
Sbjct: 632 KRRVSH-SPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 574 PP--EAPHPGKRSCQKSPAQQEPPQ------RQTVGTKQPKKPVKASA-------RAGSR 618
P +P P +R SP +++ P R+ T +PKK KA++ R S
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
Query: 619 TSLQGEREPGLL-------PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEK-- 669
S+ G EP P S+ ++ P V K A S P P+ P +S++
Sbjct: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK----KAKSPTPSPSPPRNSDQEG 806
Query: 670 ----------------------KKHK---------------------SSLPAPSKALSGP 686
KKHK ++ A + ++ P
Sbjct: 807 GGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAP 866
Query: 687 EP-------AKDNVED 695
EP A+DN++D
Sbjct: 867 EPKKETESEAEDNLDD 882
Score = 53.9 bits (128), Expect = 9e-07
Identities = 75/331 (22%), Positives = 123/331 (37%), Gaps = 35/331 (10%)
Query: 635 RDQTSKDKPKVKTKGR--PRAAASNEPKP---AVPPSSEKKKHKSSLPAPSKALSGPEPA 689
RD+ K+ + K + PR S P P + P E+K+ S P P PA
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
Query: 690 KDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL 749
+ +++TPE L + P + TS + V E + + P P +++K
Sbjct: 214 PEK-KEKTPE---LPEPSVKVKEPSVQEATSTSDILK-VPKPEPIPEPKEPSPEKNSKKE 268
Query: 750 SPLRDTPPPQSLMVKITLDLLSRIP---QPPGK-GSRQRKAEDKQPPAGKKHSSEKRSSD 805
T P K SR P +P + SR R ++ P+ ++ S +R +
Sbjct: 269 KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRT- 327
Query: 806 SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSR----------- 854
++ + R ++ R + SSSSSSS S KP +
Sbjct: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR 387
Query: 855 --PSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHK---- 908
PS+ ++ P PP + + P ++S R + P S + HK
Sbjct: 388 LSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK 447
Query: 909 ---DSSIPKQRRVEGKGSRSSSEHKGSSGDT 936
S PK R+VE S K ++ D+
Sbjct: 448 RESPSPAPKPRKVELSESEEDKGGKMAAADS 478
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/157 (24%), Positives = 60/157 (38%), Gaps = 7/157 (4%)
Query: 782 RQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSS--- 838
+QR+ E ++ + KK +K D K + + K E R +K R + S
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRR 191
Query: 839 --SSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDP 896
S S +TK PS KKE P P S K +P+++ + +D
Sbjct: 192 ERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP--EPSVKVKEPSVQEATSTSDILKVPK 249
Query: 897 PKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSS 933
P+ K + + K++ E RS S K S
Sbjct: 250 PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
Score = 38.5 bits (88), Expect = 0.039
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 13/159 (8%)
Query: 807 SSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLP 866
S+ L K++ +R + +K+ K+ KESS+ K R S +K P
Sbjct: 121 SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP 180
Query: 867 PPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSS 926
P ++ + P + +R + KS S + + K P+ K S
Sbjct: 181 SP------RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
Query: 927 SEHKGSSGD---TANPFPVPS----LPNGNSKPGKPQVK 958
+ S+ D P P+P P NSK K + K
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 94.4 bits (233), Expect = 6e-19
Identities = 208/937 (22%), Positives = 325/937 (34%), Gaps = 202/937 (21%)
Query: 203 SLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDS 262
SLPSP P PI P Q G + G PAK P + +
Sbjct: 297 SLPSPSKP--PIQQPTPGKPPAQQP----GHEKSQPG--PAKPPAQPSGLTKPLAQQPGT 348
Query: 263 LVAPAQPPSQTFPP--PSLPSKSVAMQ---QKPT-------AYVRPMDGQDQAPSESP-E 309
+ P QPP T PP P P+K A Q +KP+ A +P G + P++ P
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGP 407
Query: 310 LKP------LPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEM 363
KP P+ QQ ++ K P K V+Q ++ +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQ------ 453
Query: 364 THSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSML 423
+ P +A T T PS+ P P K + Q S+K S T
Sbjct: 454 --AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 424 EDDLQLSDSEDSDSEQTPEKPPSS---SAPPSAPQSLPEPVASAHSSSAESESTSDSDSS 480
+ Q ++ S + KPPS SA PSA Q P ++ S+ S++ S
Sbjct: 512 Q---QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 481 SDSESESSSSDSEENEPLETPAP----------EPEP--------------------PTT 510
+ S S+ + P +T P PE P
Sbjct: 569 PPTVSPSAKQPPSQGLP-KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 511 NKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATS---------QEHSESKD 561
+ ++ WL Q G + P P+ K + + TS Q+ S KD
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKD 687
Query: 562 PPPKSS-SKAP---RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGS 617
PK SKAP + PP P + A+Q P PK+P S + +
Sbjct: 688 AAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 618 RTSLQGEREPGL------LPYGSRDQTSKDKPKVKTKGR-------PRAAASNEPKPAVP 664
+ ++P + L S T D P K + + P S +P + P
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 665 PSSEKKK--HKSSLPAP---SKALSGPEPAKDNV-----------EDRTPEHFALVPLTE 708
P+ EK ++P P SK +S P P+ ++ E+ + P +
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 709 SQGPPHSG---------SGSRTSGCRQAVVVQEDSRKDRLPL-PLRDTKLLSPLRDTPPP 758
++ P +G +Q+ QE SR+ L L + D P T P
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---TTPQ 924
Query: 759 QSLMVKI----------TLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSS 808
+++ K+ +L+S QP A KQ PA S +S
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP--------SQPPTS 976
Query: 809 KLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP 868
+ K G+A K I ++KE K+ ++ E + P+ +++ KK PP
Sbjct: 977 QGPPKSTGQAP-PAPAKSIPVKKETKAPAAEKLEPKAEQA---PTVKRTETEKK----PP 1028
Query: 869 PVSSSSQKPAKPA-------LKRSRREADTC----------GQDPPKSASSTKSNHKDSS 911
P+ S A+P L++S + TC +DPP + T+ ++ +
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 912 I--------------------PKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSK 951
+ QR + G+ SG A+P PVP+ +
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
Query: 952 PGKPQVKFDKQQADLHMREAKKM---KQKAELMTDRV 985
PQVK K+Q EA+K+ K K L +++
Sbjct: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKI 1185
Score = 72.0 bits (175), Expect = 3e-12
Identities = 166/743 (22%), Positives = 261/743 (35%), Gaps = 160/743 (21%)
Query: 277 PSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLT 336
PSLPS S Q+PT P + P +P E K++
Sbjct: 296 PSLPSPSKPPIQQPT------------PGKPPAQQPGHE----------------KSQPG 327
Query: 337 KLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPF-PTKDSQHV 395
K P+Q T + L + + PP + P T +P P P K
Sbjct: 328 PAKPPAQPSGLT---------KPLAQQPGTVKPP---VQPPGTTKPPAQPLGPAKPPAQ- 374
Query: 396 SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQ 455
T S+ S+ Q G ++ ++ +TP + P + PP+
Sbjct: 375 ----------QTGSEKPSSEQPGPKAL---------AQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 456 SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQL 515
P+P+A + S ++ P +TP +P P Q
Sbjct: 416 GTPKPLA---------------------QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 516 DNWLTKVSQ--PAAPP-EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR 572
T Q P PP + P +PP P+ G + Q S PP + +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPP---PQQPGPAKPPPQQPGSAK---PPSQQPGSTK 508
Query: 573 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTK---QPKKPVKASARAGSR-TSLQGEREPG 628
PP+ P P K S Q+ P +PP +Q K Q P K SA+ ++ S G +P
Sbjct: 509 PPPQQPGPAKPSPQQ-PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 629 LLPYGSRDQTSKDKPKVKTKGRPRAAA----SNEPKPAVPPSSEKKKHKSSLPAPSKALS 684
P S ++K P ++G P+ + E VP EK + + S
Sbjct: 568 QPPTVS--PSAKQPP---SQGLPKTICPLCNTTELLLHVP---EKANFNTCTECQTTVCS 619
Query: 685 ----GPEPAKDNVED--------RTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQE 732
P P V++ + L P+ S P +T+ V +
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK-----LKTAPVTTTSAVSK 674
Query: 733 DSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPP 792
S + + P +D L P P+ + QP GS KA KQPP
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--------PLVKQPTLHGSPSAKA--KQPP 724
Query: 793 AGKKHSSEKRSSDSSSKLAKKRKGEAERDCD-----NKKIRLEKEIKSQSSSSSSSHKES 847
+DS SK A ++ + D + K + K +K + SSS S
Sbjct: 725 ----------EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS---S 771
Query: 848 SKTKPSRPSSQ-SSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTK-- 904
+ TKP PSS+ S+ E PP+ + S KP++ + + + P+ AS +K
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 905 SNHKDSSIPKQRR----VEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
S+ SS K ++ V+ K ++ K S A P P S +P Q
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 961 KQQADLHMREAKKMKQKAELMTD 983
QQ+ ++++ +TD
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITD 914
Score = 67.0 bits (162), Expect = 1e-10
Identities = 144/674 (21%), Positives = 235/674 (34%), Gaps = 110/674 (16%)
Query: 259 PQDSLVAPAQPPSQTFPP------PSLPSKSVAMQQ--KPTAYVRPMDGQDQAPS---ES 307
P AP+QPP+ PP P P+KS+ +++ K A + +QAP+
Sbjct: 963 PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 308 PELKPLP-EDYRQQTFEKTDLKVPAKAKL------------TKLKMPSQSVEQTYSNEVH 354
E KP P +D + T E +P K + T+L + S+ ++
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD-PPNFNTCTE 1081
Query: 355 CVEEILKEMTHSWPPPLTAIH-------------------------TPSTAEPSKFPFPT 389
C ++ + P LT I PS + S P PT
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 390 KDSQHVSSVT--------QNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
+ S ++V Q Q+ + K + T SM E + ++ E
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM-EKIPPMVTTDQKQEESKL 1200
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
EK +S+ P LPE E + S+ E + + D + +T
Sbjct: 1201 EKDKASALQEKKP--LPE---EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTS 1255
Query: 502 APEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP-------PRRHPESKGSSDSATSQ 554
APE + K Q+ K+ AP +P P P+S D T++
Sbjct: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315
Query: 555 EHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASAR 614
E PP A P+ PGK +K E + T ++QPK P S
Sbjct: 1316 TIKEQPQPPCT-------AKPDQVEPGKEKTEK-----EDDKSDTSSSQQPKSPQGLSDT 1363
Query: 615 AGSRTSLQGE--REPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKH 672
S + P L+P +D KG + + S E P+ P K +
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKD---------ILKGLKKDSFSQESSPSSPSDLAKLES 1414
Query: 673 K--SSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVV 730
S L A + L A + E +T H + Q S S + + +
Sbjct: 1415 TVLSILEAQASTL-----ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEI- 1468
Query: 731 QEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKIT-LDLLSRIPQPPGKGSRQRKAEDK 789
++S+++R +DT +D P + K +D ++ +P ++E+
Sbjct: 1469 -KESQEER-----KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENS 1522
Query: 790 QPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSK 849
P K+ +S SS K + E D K+I +E +S S ++
Sbjct: 1523 PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI-IEMSADEDASGSEDDEFIRNQ 1581
Query: 850 TKPSRPSSQSSKKE 863
K S++S KKE
Sbjct: 1582 LKEISSSTESQKKE 1595
Score = 60.5 bits (145), Expect = 1e-08
Identities = 97/518 (18%), Positives = 182/518 (35%), Gaps = 46/518 (8%)
Query: 447 SSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPE 506
SS PP P+P A ++S +T S S S+ S + T E
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148
Query: 507 PPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP-PPK 565
+ + +L++V+ +A P +S+ S + T ++ K+ P+
Sbjct: 149 KSS----MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPE 204
Query: 566 SSSKAP-RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGE 624
K P + P P P ++ + P QQ+ + ++ ++QP+K +K S G+ +QG
Sbjct: 205 GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK-SISSQQPEK-IK-SQPPGTGKPIQGP 261
Query: 625 REPGLLPYGSRD-QTSKDKPKVKTKG--RPRAAASNEPKPAVPPSSEKKKHKSSLPAPSK 681
+ + Q +P+ K R + + P P+ PP + K P
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321
Query: 682 ALSGPEPAKDNVEDRTPEHFALVPLTESQG---PPHSGSGSRTSGCRQAVVVQEDSRKDR 738
S P PAK + PL + G PP G+ + +
Sbjct: 322 EKSQPGPAKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP------ 371
Query: 739 LPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQ-RKAEDKQPPAGKKH 797
P + T P + P P++L QPPG G ++ +PP +
Sbjct: 372 ---PAQQTGSEKPSSEQPGPKALA------------QPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 798 SSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSS 857
+ + + + K G + ++ K + + + +T P++P S
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTP-----VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 858 QSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRR 917
Q PP + P +P + + + PP+ K + + K
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 918 VEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP 955
+ ++ S++ + +A P G+ KP +P
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Score = 60.5 bits (145), Expect = 1e-08
Identities = 184/901 (20%), Positives = 303/901 (33%), Gaps = 170/901 (18%)
Query: 89 KPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLH- 147
KPK P + + + SSS T+ P+S S P + +P S
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATT----KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808
Query: 148 -AKSCGPPDSQHLTQDRLGQEGF---GSSHHKKGDRRADG-----DHCASVTDSAPEREL 198
+ P DS+ + + + G S KG ++ D + + T +P+ +
Sbjct: 809 TGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 199 SPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNN------SKGYCPAKSPKDLAVK 252
P+ SP PP P + QT+P Q S K S S P P
Sbjct: 869 KPMPK-GSPTPP-GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926
Query: 253 VHDKE--------TPQDSLVAPA-QPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQA 303
V K + +L++ A QP + P P K +P P QA
Sbjct: 927 VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986
Query: 304 PSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEM 363
P + P+ K + K PA KL + +V++T
Sbjct: 987 PPAPAKSIPV----------KKETKAPAAEKLEPKAEQAPTVKRTE-------------- 1022
Query: 364 THSWPPPLTAIHTPSTAEPSKFPFPTK---DSQHVSSVTQNQKQYDTSSKTHSNSQQGTS 420
T PPP+ + TAEP K PTK + S+ + + + SK N T
Sbjct: 1023 TEKKPPPIKDSKS-LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 421 -----------------SMLEDDLQLS-DSEDSDSEQTPE---KPPSSSAPPSAPQSLPE 459
+ +++ L L+ ++ + S Q + PP+ S P ++P +P
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 460 PVASAHSSSAESESTSDSDSSSDSESESSSSDSEE---NEPLETPAPEPEPP--TTNKWQ 514
SS++ + + + +++E+ + ET + E PP TT++ Q
Sbjct: 1142 ------ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQ 1195
Query: 515 LDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP 574
++ L K A + P E E K S+ + E K P P+ P A
Sbjct: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE--KKPLLEEKKPTPEDKKLLPEAK 1253
Query: 575 PEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
AP K KS Q + + + G PK + + G + + E P P
Sbjct: 1254 TSAPEEQKHDLLKS--QVQIAEEKLEGRVAPK-----TVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSL-----PAPSKALSGPEPA 689
+ K +K + +P A + +EK+ KS P + LS +
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366
Query: 690 KDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL 749
D + E +L+P E G ++ QE S
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKD---------ILKGLKKDSFSQESS--------------- 1402
Query: 750 SPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809
P S + K+ +LS I + K+E K P S K
Sbjct: 1403 ------PSSPSDLAKLESTVLS-ILEAQASTLADEKSEKKTQP--------HEVSPEQPK 1447
Query: 810 LAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
+K + +E LE I + S ++ + K S+ SSK
Sbjct: 1448 DQEKTQSLSET--------LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK----- 1494
Query: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
++S D + P + S ++S +P+++R GS SS E+
Sbjct: 1495 -------------EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 930 K 930
K
Sbjct: 1542 K 1542
Score = 38.9 bits (89), Expect = 0.030
Identities = 116/555 (20%), Positives = 180/555 (32%), Gaps = 122/555 (21%)
Query: 304 PSESPELKPLPEDYRQQTFEKTDL-------KVPAKAKLTK------LKMPSQSVEQTYS 350
P SP P+ ED + T + + V + A LT L +P + Q +S
Sbjct: 2078 PGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFS 2137
Query: 351 NE----------VHCVEEILKE----MTHSWP------------PPLTAIHTPSTAEPSK 384
E ++EI+ +T+S P P LT+ + S
Sbjct: 2138 TEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSS 2197
Query: 385 FPFPTKDS------QHVSSVTQNQKQYDTSSKTH------------------SNSQQGTS 420
P T DS + V +T+ + + SS T+ + G +
Sbjct: 2198 SPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRA 2257
Query: 421 SMLEDDLQLSDSEDSDSEQT---PEKPPSSSAPPSAPQSLPEPVASAHSSSAES------ 471
S + LSD S E PE P + + S +PV A +
Sbjct: 2258 SADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVL 2317
Query: 472 ESTSDSDSSSDSESESSSSDSEENEPLET--PAPEPEPPTTNKWQLDNWLTKVSQPAAPP 529
E+ D ++SS S++ + P + P E +T + + + P
Sbjct: 2318 EAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377
Query: 530 EGPRSTE--PPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQK 587
G S P + P + SS ++Q PPP P PP P P
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP------T 2431
Query: 588 SPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647
SP T PKK + ++ + T P T + +++
Sbjct: 2432 SPKP----------TILPKKKLTVASPVTTAT-----------PLFDAVTTLETTAVLRS 2470
Query: 648 KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
G P P VPP SS+P+ PEP+K + P+ T
Sbjct: 2471 NGLPVTRICTTAPPPVPPK------PSSIPSGLVFTHRPEPSKPPI---APKPVIPQLPT 2521
Query: 708 ESQGP----PHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMV 763
+Q P P S TS +V D +LP P T LSP + P+
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADY---KLPSP---TSPLSPHSNKSSPRFSKS 2575
Query: 764 KITLDLLSRIPQPPG 778
++ +P PG
Sbjct: 2576 LTETYVVITLPSEPG 2590
Score = 37.4 bits (85), Expect = 0.087
Identities = 47/196 (23%), Positives = 73/196 (37%), Gaps = 19/196 (9%)
Query: 420 SSMLEDDLQLSDSEDSDS---EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
+S + D S+ S ++ PE S +S E +S H+SS ++
Sbjct: 1673 NSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPT 1732
Query: 477 SDSSSDSESESSSS----DSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
S SS D +S+SS S +S++ P PT + L + + E
Sbjct: 1733 SVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ 1792
Query: 533 RSTEPPRRHPESKGS---SDSATSQEHSESKDPPPKSSSKAPRAPP--------EAPHPG 581
R E +R SK S D +Q E PP + S A P E
Sbjct: 1793 REIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 582 KRSCQK-SPAQQEPPQ 596
+ SC + SP+ + P+
Sbjct: 1853 RSSCSEYSPSIESDPE 1868
Score = 36.2 bits (82), Expect = 0.19
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 4/138 (2%)
Query: 790 QPPAGKKHSSEKRSSDSSSKLAKKRKG-EAERDCDNKKIRLEKEIKSQSSSSSSSHKESS 848
Q A K +SS RS SS + +RD + +RL+ + S S S+
Sbjct: 4276 QDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSA 4335
Query: 849 KTKP-SRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNH 907
+TKP S P SQS + +P +S + P P + G PP SA +
Sbjct: 4336 RTKPTSLPISQSRGR--IPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFG 4393
Query: 908 KDSSIPKQRRVEGKGSRS 925
S+P+ ++ + SR+
Sbjct: 4394 SSHSLPEVQQHMREESRT 4411
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 94.4 bits (233), Expect = 6e-19
Identities = 208/937 (22%), Positives = 325/937 (34%), Gaps = 202/937 (21%)
Query: 203 SLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDS 262
SLPSP P PI P Q G + G PAK P + +
Sbjct: 297 SLPSPSKP--PIQQPTPGKPPAQQP----GHEKSQPG--PAKPPAQPSGLTKPLAQQPGT 348
Query: 263 LVAPAQPPSQTFPP--PSLPSKSVAMQ---QKPT-------AYVRPMDGQDQAPSESP-E 309
+ P QPP T PP P P+K A Q +KP+ A +P G + P++ P
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGP 407
Query: 310 LKP------LPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEM 363
KP P+ QQ ++ K P K V+Q ++ +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQ------ 453
Query: 364 THSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSML 423
+ P +A T T PS+ P P K + Q S+K S T
Sbjct: 454 --AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 424 EDDLQLSDSEDSDSEQTPEKPPSS---SAPPSAPQSLPEPVASAHSSSAESESTSDSDSS 480
+ Q ++ S + KPPS SA PSA Q P ++ S+ S++ S
Sbjct: 512 Q---QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 481 SDSESESSSSDSEENEPLETPAP----------EPEP--------------------PTT 510
+ S S+ + P +T P PE P
Sbjct: 569 PPTVSPSAKQPPSQGLP-KTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 511 NKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATS---------QEHSESKD 561
+ ++ WL Q G + P P+ K + + TS Q+ S KD
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKD 687
Query: 562 PPPKSS-SKAP---RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGS 617
PK SKAP + PP P + A+Q P PK+P S + +
Sbjct: 688 AAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 618 RTSLQGEREPGL------LPYGSRDQTSKDKPKVKTKGR-------PRAAASNEPKPAVP 664
+ ++P + L S T D P K + + P S +P + P
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 665 PSSEKKK--HKSSLPAP---SKALSGPEPAKDNV-----------EDRTPEHFALVPLTE 708
P+ EK ++P P SK +S P P+ ++ E+ + P +
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 709 SQGPPHSG---------SGSRTSGCRQAVVVQEDSRKDRLPL-PLRDTKLLSPLRDTPPP 758
++ P +G +Q+ QE SR+ L L + D P T P
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---TTPQ 924
Query: 759 QSLMVKI----------TLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSS 808
+++ K+ +L+S QP A KQ PA S +S
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP--------SQPPTS 976
Query: 809 KLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP 868
+ K G+A K I ++KE K+ ++ E + P+ +++ KK PP
Sbjct: 977 QGPPKSTGQAP-PAPAKSIPVKKETKAPAAEKLEPKAEQA---PTVKRTETEKK----PP 1028
Query: 869 PVSSSSQKPAKPA-------LKRSRREADTC----------GQDPPKSASSTKSNHKDSS 911
P+ S A+P L++S + TC +DPP + T+ ++ +
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 912 I--------------------PKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSK 951
+ QR + G+ SG A+P PVP+ +
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
Query: 952 PGKPQVKFDKQQADLHMREAKKM---KQKAELMTDRV 985
PQVK K+Q EA+K+ K K L +++
Sbjct: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKI 1185
Score = 72.0 bits (175), Expect = 3e-12
Identities = 166/743 (22%), Positives = 261/743 (35%), Gaps = 160/743 (21%)
Query: 277 PSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLT 336
PSLPS S Q+PT P + P +P E K++
Sbjct: 296 PSLPSPSKPPIQQPT------------PGKPPAQQPGHE----------------KSQPG 327
Query: 337 KLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPF-PTKDSQHV 395
K P+Q T + L + + PP + P T +P P P K
Sbjct: 328 PAKPPAQPSGLT---------KPLAQQPGTVKPP---VQPPGTTKPPAQPLGPAKPPAQ- 374
Query: 396 SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQ 455
T S+ S+ Q G ++ ++ +TP + P + PP+
Sbjct: 375 ----------QTGSEKPSSEQPGPKAL---------AQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 456 SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQL 515
P+P+A + S ++ P +TP +P P Q
Sbjct: 416 GTPKPLA---------------------QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 516 DNWLTKVSQ--PAAPP-EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR 572
T Q P PP + P +PP P+ G + Q S PP + +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPP---PQQPGPAKPPPQQPGSAK---PPSQQPGSTK 508
Query: 573 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTK---QPKKPVKASARAGSR-TSLQGEREPG 628
PP+ P P K S Q+ P +PP +Q K Q P K SA+ ++ S G +P
Sbjct: 509 PPPQQPGPAKPSPQQ-PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 629 LLPYGSRDQTSKDKPKVKTKGRPRAAA----SNEPKPAVPPSSEKKKHKSSLPAPSKALS 684
P S ++K P ++G P+ + E VP EK + + S
Sbjct: 568 QPPTVS--PSAKQPP---SQGLPKTICPLCNTTELLLHVP---EKANFNTCTECQTTVCS 619
Query: 685 ----GPEPAKDNVED--------RTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQE 732
P P V++ + L P+ S P +T+ V +
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK-----LKTAPVTTTSAVSK 674
Query: 733 DSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPP 792
S + + P +D L P P+ + QP GS KA KQPP
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--------PLVKQPTLHGSPSAKA--KQPP 724
Query: 793 AGKKHSSEKRSSDSSSKLAKKRKGEAERDCD-----NKKIRLEKEIKSQSSSSSSSHKES 847
+DS SK A ++ + D + K + K +K + SSS S
Sbjct: 725 ----------EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS---S 771
Query: 848 SKTKPSRPSSQ-SSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTK-- 904
+ TKP PSS+ S+ E PP+ + S KP++ + + + P+ AS +K
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 905 SNHKDSSIPKQRR----VEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
S+ SS K ++ V+ K ++ K S A P P S +P Q
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 961 KQQADLHMREAKKMKQKAELMTD 983
QQ+ ++++ +TD
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITD 914
Score = 67.0 bits (162), Expect = 1e-10
Identities = 144/674 (21%), Positives = 235/674 (34%), Gaps = 110/674 (16%)
Query: 259 PQDSLVAPAQPPSQTFPP------PSLPSKSVAMQQ--KPTAYVRPMDGQDQAPS---ES 307
P AP+QPP+ PP P P+KS+ +++ K A + +QAP+
Sbjct: 963 PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 308 PELKPLP-EDYRQQTFEKTDLKVPAKAKL------------TKLKMPSQSVEQTYSNEVH 354
E KP P +D + T E +P K + T+L + S+ ++
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD-PPNFNTCTE 1081
Query: 355 CVEEILKEMTHSWPPPLTAIH-------------------------TPSTAEPSKFPFPT 389
C ++ + P LT I PS + S P PT
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 390 KDSQHVSSVT--------QNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
+ S ++V Q Q+ + K + T SM E + ++ E
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM-EKIPPMVTTDQKQEESKL 1200
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
EK +S+ P LPE E + S+ E + + D + +T
Sbjct: 1201 EKDKASALQEKKP--LPE---EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTS 1255
Query: 502 APEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP-------PRRHPESKGSSDSATSQ 554
APE + K Q+ K+ AP +P P P+S D T++
Sbjct: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315
Query: 555 EHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASAR 614
E PP A P+ PGK +K E + T ++QPK P S
Sbjct: 1316 TIKEQPQPPCT-------AKPDQVEPGKEKTEK-----EDDKSDTSSSQQPKSPQGLSDT 1363
Query: 615 AGSRTSLQGE--REPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKH 672
S + P L+P +D KG + + S E P+ P K +
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKD---------ILKGLKKDSFSQESSPSSPSDLAKLES 1414
Query: 673 K--SSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVV 730
S L A + L A + E +T H + Q S S + + +
Sbjct: 1415 TVLSILEAQASTL-----ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEI- 1468
Query: 731 QEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKIT-LDLLSRIPQPPGKGSRQRKAEDK 789
++S+++R +DT +D P + K +D ++ +P ++E+
Sbjct: 1469 -KESQEER-----KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENS 1522
Query: 790 QPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSK 849
P K+ +S SS K + E D K+I +E +S S ++
Sbjct: 1523 PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI-IEMSADEDASGSEDDEFIRNQ 1581
Query: 850 TKPSRPSSQSSKKE 863
K S++S KKE
Sbjct: 1582 LKEISSSTESQKKE 1595
Score = 60.5 bits (145), Expect = 1e-08
Identities = 97/518 (18%), Positives = 182/518 (35%), Gaps = 46/518 (8%)
Query: 447 SSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPE 506
SS PP P+P A ++S +T S S S+ S + T E
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148
Query: 507 PPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP-PPK 565
+ + +L++V+ +A P +S+ S + T ++ K+ P+
Sbjct: 149 KSS----MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPE 204
Query: 566 SSSKAP-RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGE 624
K P + P P P ++ + P QQ+ + ++ ++QP+K +K S G+ +QG
Sbjct: 205 GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK-SISSQQPEK-IK-SQPPGTGKPIQGP 261
Query: 625 REPGLLPYGSRD-QTSKDKPKVKTKG--RPRAAASNEPKPAVPPSSEKKKHKSSLPAPSK 681
+ + Q +P+ K R + + P P+ PP + K P
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321
Query: 682 ALSGPEPAKDNVEDRTPEHFALVPLTESQG---PPHSGSGSRTSGCRQAVVVQEDSRKDR 738
S P PAK + PL + G PP G+ + +
Sbjct: 322 EKSQPGPAKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP------ 371
Query: 739 LPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQ-RKAEDKQPPAGKKH 797
P + T P + P P++L QPPG G ++ +PP +
Sbjct: 372 ---PAQQTGSEKPSSEQPGPKALA------------QPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 798 SSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSS 857
+ + + + K G + ++ K + + + +T P++P S
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTP-----VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 858 QSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRR 917
Q PP + P +P + + + PP+ K + + K
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 918 VEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP 955
+ ++ S++ + +A P G+ KP +P
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Score = 60.5 bits (145), Expect = 1e-08
Identities = 184/901 (20%), Positives = 303/901 (33%), Gaps = 170/901 (18%)
Query: 89 KPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLH- 147
KPK P + + + SSS T+ P+S S P + +P S
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATT----KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808
Query: 148 -AKSCGPPDSQHLTQDRLGQEGF---GSSHHKKGDRRADG-----DHCASVTDSAPEREL 198
+ P DS+ + + + G S KG ++ D + + T +P+ +
Sbjct: 809 TGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 199 SPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNN------SKGYCPAKSPKDLAVK 252
P+ SP PP P + QT+P Q S K S S P P
Sbjct: 869 KPMPK-GSPTPP-GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926
Query: 253 VHDKE--------TPQDSLVAPA-QPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQA 303
V K + +L++ A QP + P P K +P P QA
Sbjct: 927 VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986
Query: 304 PSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEM 363
P + P+ K + K PA KL + +V++T
Sbjct: 987 PPAPAKSIPV----------KKETKAPAAEKLEPKAEQAPTVKRTE-------------- 1022
Query: 364 THSWPPPLTAIHTPSTAEPSKFPFPTK---DSQHVSSVTQNQKQYDTSSKTHSNSQQGTS 420
T PPP+ + TAEP K PTK + S+ + + + SK N T
Sbjct: 1023 TEKKPPPIKDSKS-LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 421 -----------------SMLEDDLQLS-DSEDSDSEQTPE---KPPSSSAPPSAPQSLPE 459
+ +++ L L+ ++ + S Q + PP+ S P ++P +P
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 460 PVASAHSSSAESESTSDSDSSSDSESESSSSDSEE---NEPLETPAPEPEPP--TTNKWQ 514
SS++ + + + +++E+ + ET + E PP TT++ Q
Sbjct: 1142 ------ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQ 1195
Query: 515 LDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP 574
++ L K A + P E E K S+ + E K P P+ P A
Sbjct: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE--KKPLLEEKKPTPEDKKLLPEAK 1253
Query: 575 PEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
AP K KS Q + + + G PK + + G + + E P P
Sbjct: 1254 TSAPEEQKHDLLKS--QVQIAEEKLEGRVAPK-----TVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSL-----PAPSKALSGPEPA 689
+ K +K + +P A + +EK+ KS P + LS +
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366
Query: 690 KDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL 749
D + E +L+P E G ++ QE S
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKD---------ILKGLKKDSFSQESS--------------- 1402
Query: 750 SPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809
P S + K+ +LS I + K+E K P S K
Sbjct: 1403 ------PSSPSDLAKLESTVLS-ILEAQASTLADEKSEKKTQP--------HEVSPEQPK 1447
Query: 810 LAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
+K + +E LE I + S ++ + K S+ SSK
Sbjct: 1448 DQEKTQSLSET--------LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK----- 1494
Query: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
++S D + P + S ++S +P+++R GS SS E+
Sbjct: 1495 -------------EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 930 K 930
K
Sbjct: 1542 K 1542
Score = 38.9 bits (89), Expect = 0.030
Identities = 116/555 (20%), Positives = 180/555 (32%), Gaps = 122/555 (21%)
Query: 304 PSESPELKPLPEDYRQQTFEKTDL-------KVPAKAKLTK------LKMPSQSVEQTYS 350
P SP P+ ED + T + + V + A LT L +P + Q +S
Sbjct: 2078 PGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFS 2137
Query: 351 NE----------VHCVEEILKE----MTHSWP------------PPLTAIHTPSTAEPSK 384
E ++EI+ +T+S P P LT+ + S
Sbjct: 2138 TEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSS 2197
Query: 385 FPFPTKDS------QHVSSVTQNQKQYDTSSKTH------------------SNSQQGTS 420
P T DS + V +T+ + + SS T+ + G +
Sbjct: 2198 SPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRA 2257
Query: 421 SMLEDDLQLSDSEDSDSEQT---PEKPPSSSAPPSAPQSLPEPVASAHSSSAES------ 471
S + LSD S E PE P + + S +PV A +
Sbjct: 2258 SADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVL 2317
Query: 472 ESTSDSDSSSDSESESSSSDSEENEPLET--PAPEPEPPTTNKWQLDNWLTKVSQPAAPP 529
E+ D ++SS S++ + P + P E +T + + + P
Sbjct: 2318 EAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377
Query: 530 EGPRSTE--PPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQK 587
G S P + P + SS ++Q PPP P PP P P
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP------T 2431
Query: 588 SPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647
SP T PKK + ++ + T P T + +++
Sbjct: 2432 SPKP----------TILPKKKLTVASPVTTAT-----------PLFDAVTTLETTAVLRS 2470
Query: 648 KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
G P P VPP SS+P+ PEP+K + P+ T
Sbjct: 2471 NGLPVTRICTTAPPPVPPK------PSSIPSGLVFTHRPEPSKPPI---APKPVIPQLPT 2521
Query: 708 ESQGP----PHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMV 763
+Q P P S TS +V D +LP P T LSP + P+
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADY---KLPSP---TSPLSPHSNKSSPRFSKS 2575
Query: 764 KITLDLLSRIPQPPG 778
++ +P PG
Sbjct: 2576 LTETYVVITLPSEPG 2590
Score = 37.4 bits (85), Expect = 0.087
Identities = 47/196 (23%), Positives = 73/196 (37%), Gaps = 19/196 (9%)
Query: 420 SSMLEDDLQLSDSEDSDS---EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
+S + D S+ S ++ PE S +S E +S H+SS ++
Sbjct: 1673 NSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPT 1732
Query: 477 SDSSSDSESESSSS----DSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
S SS D +S+SS S +S++ P PT + L + + E
Sbjct: 1733 SVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ 1792
Query: 533 RSTEPPRRHPESKGS---SDSATSQEHSESKDPPPKSSSKAPRAPP--------EAPHPG 581
R E +R SK S D +Q E PP + S A P E
Sbjct: 1793 REIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 582 KRSCQK-SPAQQEPPQ 596
+ SC + SP+ + P+
Sbjct: 1853 RSSCSEYSPSIESDPE 1868
Score = 36.2 bits (82), Expect = 0.19
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 4/138 (2%)
Query: 790 QPPAGKKHSSEKRSSDSSSKLAKKRKG-EAERDCDNKKIRLEKEIKSQSSSSSSSHKESS 848
Q A K +SS RS SS + +RD + +RL+ + S S S+
Sbjct: 4276 QDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSA 4335
Query: 849 KTKP-SRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNH 907
+TKP S P SQS + +P +S + P P + G PP SA +
Sbjct: 4336 RTKPTSLPISQSRGR--IPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFG 4393
Query: 908 KDSSIPKQRRVEGKGSRS 925
S+P+ ++ + SR+
Sbjct: 4394 SSHSLPEVQQHMREESRT 4411
Score = 36.2 bits (82), Expect = 0.19
Identities = 50/204 (24%), Positives = 71/204 (34%), Gaps = 30/204 (14%)
Query: 794 GKKHSSEKRSSDSSSKLAKKRKGEAERDC--DNKKIRLEKEIKSQSSSSSSSHKESSKTK 851
GK HSS+ + K R D D + +EK S SS SSS
Sbjct: 4835 GKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHG 4894
Query: 852 PSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPK------SASSTKS 905
PSR S++S V+ + + A A+ + P K + SS +
Sbjct: 4895 PSRSQSKTS---------VTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVST 4945
Query: 906 NHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSL----PNGNSKPGKP--QVKF 959
SS G G SE S+ N FP+P + NG +P V
Sbjct: 4946 GSSGSSF-------GSGYSVDSEGSSSTAGETNLFPIPRIGKMGQNGQEPVKQPGVGVGL 4998
Query: 960 DKQQADLHMREAKKMKQKAELMTD 983
+A + K+ K E+ TD
Sbjct: 4999 ADTEAKTQVMGEIKIALKKEMKTD 5022
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 90.5 bits (223), Expect = 9e-18
Identities = 146/753 (19%), Positives = 268/753 (35%), Gaps = 94/753 (12%)
Query: 192 SAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAV 251
S +E +P +P P P + ++ P T + +K P +PK+ A
Sbjct: 226 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP----APTTTKEPAPT-TPKEPAP 280
Query: 252 KVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELK 311
+ P + AP P P P+ P K K A P ++ P+ E
Sbjct: 281 TTTKEPAPTTTKSAPTTPKE---PAPTTPKKPAPTTPKEPA---PTTPKEPTPTTPKEPA 334
Query: 312 PLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPL 371
P ++ T ++ P K T K P+ + T + T P P
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT---TPKEPAPTTTKEPSPTTPKEPAPT 391
Query: 372 TAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSD 431
T P+T +K P PT S+ T ++ T++K + + +
Sbjct: 392 TTKSAPTT---TKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 432 SEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSD 491
+ + TP++P ++ AP + EP + +A + + ++ + + ++
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 492 SEENEPLETPAPEPEPPT-TNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P E PE PT T + K + P P E P T P P +
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTTPKEPAP 564
Query: 551 ATSQEHSES----------KDPPPKSSSK-APR--APPEAPHPGKRSCQK----SPAQQE 593
T +E + + K+P P + K AP+ AP P +C K +P
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 594 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
P + PK+P + + + T+L +EP P + K+ TKG P +
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTL---KEPA--PTTPKKPAPKELAPTTTKG-PTS 678
Query: 654 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP 713
S++P P P + K P K +PA P T PP
Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPA---------------PTTPETPPP 718
Query: 714 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI 773
+ S + ++ + + SP TP L + T L
Sbjct: 719 TTSEVSTPTTTKEPTTIHK-----------------SPDESTP---ELSAEPTPKALENS 758
Query: 774 PQPPGKGSRQRKAEDK--QPPAGKKHSSEK------RSSDSSSKLAKKRKGEAERDCDNK 825
P+ PG + + A K K ++E+ ++ ++ K+ K+ E+ ++K
Sbjct: 759 PKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 818
Query: 826 KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRS 885
++ S ++ ++ K ++ + ++ K+ + + + ++ AKP + +
Sbjct: 819 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 878
Query: 886 RREADT-CGQDPPKSASSTKSNHKDSSIPKQRR 917
+A T Q P K+ S K ++P+ R+
Sbjct: 879 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 911
Score = 86.7 bits (213), Expect = 1e-16
Identities = 149/739 (20%), Positives = 257/739 (34%), Gaps = 94/739 (12%)
Query: 248 DLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSES 307
D V D T Q + V+ + P T P P S+ P + +
Sbjct: 96 DFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSL-----------PPNSDTSKETSL 142
Query: 308 PELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSW 367
K + ++ T K K T K +QS+E+T + ++ ++L + T
Sbjct: 143 TVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPT--- 198
Query: 368 PPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427
P T P+ P K P PT + S+ + S + + ++
Sbjct: 199 PKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 257
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
+ + +++ P AP + + P SA ++ E T+ + + E
Sbjct: 258 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 317
Query: 488 SSSDSEENEPLETPAPEP---EP-PTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRRHP 542
+ + +E P P P EP PTT K +PA P+ P T P P
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPK-----------EPAPTAPKKPAPTTPKEPAP 366
Query: 543 ESKGSSDSATSQEHSES--KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV 600
+ T++E S + K+P P ++ AP E +S +P + P +
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Query: 601 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK 660
PK+P + + + T+ +EP T+ +P T +P EP
Sbjct: 427 APTTPKEPAPTTPKKPAPTT---PKEPA--------PTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 661 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR 720
P P + K P + L+ P K TPE A P T + P +
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKP--APTTPEELA--PTTPEEPTPTTPEEPA 531
Query: 721 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPP-PQSLMVKITLDLLSRIPQPPGK 779
+ + A ++ K+ P ++ +P P P+ + P
Sbjct: 532 PTTPKAAA---PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588
Query: 780 GSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK--SQS 837
+ ++ A + P K E S+ KG A KE +
Sbjct: 589 TTPKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 838 SSSSSSHKESSKTKPSRPSSQSSKKEMLPPP---PVSSSSQKPA-------------KPA 881
++ ++ KE + T P +P+ KE+ P P S++S KPA +PA
Sbjct: 646 GTAPTTLKEPAPTTPKKPAP----KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 882 LKRSRREADTCGQDPPKSAS--STKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP 939
++ A T + PP + S ST + K+ + + S + + +A P
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-----------TIHKSPDESTPELSAEP 750
Query: 940 FPVPSLPNGNSKPGKPQVK 958
P +L N +PG P K
Sbjct: 751 TP-KALENSPKEPGVPTTK 768
Score = 52.8 bits (125), Expect = 2e-06
Identities = 83/437 (18%), Positives = 148/437 (33%), Gaps = 55/437 (12%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAK-SPKDLAVKVHDKET----- 258
P+P P P + + T + P K +PK+LA + T
Sbjct: 554 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613
Query: 259 -PQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY 317
P + P + P P+ P + K TA + P + + P
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 318 RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA-IHT 376
+ T +D P K T P + T E PPP T+ + T
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPPTTSEVST 725
Query: 377 PSTA-EPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS 435
P+T EP+ +S S K + S K T + + ++ + + +
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785
Query: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
P +++A P + + A+ + ES+ T+ + ++ +S+ +++
Sbjct: 786 TERDLRTTPETTTAAPK----MTKETATTTEKTTESKITATT-------TQVTSTTTQDT 834
Query: 496 EP-----LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P L+T P+ TT K +TE + E+ D
Sbjct: 835 TPFKITTLKTTTLAPKVTTTKKTIT------------------TTEIMNKPEETAKPKDR 876
Query: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
AT+ S++ P P+ +KAP+ P P + P P++ T T P
Sbjct: 877 ATN---SKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT-STMPELNPTS 932
Query: 611 ASARAGSRTSLQGEREP 627
A A +T+ + + P
Sbjct: 933 RIAEAMLQTTTRPNQTP 949
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/325 (19%), Positives = 114/325 (35%), Gaps = 47/325 (14%)
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
PK PV A +G + G + D ++ KV T + A P+P++P
Sbjct: 80 PKPPVVDEAGSGL--------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 131
Query: 665 PSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGC 724
P+S+ K S + E N + T +T+
Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTNKQTST------------------DGKEKTTSA 173
Query: 725 RQAVVVQEDSRKD--------RLPLPLRDTKLLSPLRDTP-PPQSLMVKITLDLLSRIPQ 775
++ +++ S KD P P +T P TP P K + P
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 776 PPGKGSRQRKAEDKQPPAGKK-HSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK 834
P S ++ P K ++ K + +++K + K +
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-----EPAP 288
Query: 835 SQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQ 894
+ + S+ ++ KE + T P +P + ++ KE P P + P +PA ++ A T +
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKP-APTTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPK 346
Query: 895 DP----PKSASSTKSNHKDSSIPKQ 915
+P PK + T + PK+
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKE 371
Score = 37.4 bits (85), Expect = 0.087
Identities = 57/302 (18%), Positives = 111/302 (36%), Gaps = 33/302 (10%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
P+P P P + +T P T +S+V + + KSP + ++ + TP+
Sbjct: 700 PAPTTPKKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 757
Query: 265 APAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEK 324
+P +P T P+ + K R + + + +P++ ++T
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT-------KETATT 810
Query: 325 TDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSK 384
T+ +K T ++ S + + T ++ LK T + P T T +T E
Sbjct: 811 TEKTTESKITATTTQVTSTTTQDTTPFKI----TTLKTTTLA-PKVTTTKKTITTTEIMN 865
Query: 385 FPFPT---KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
P T KD S T + Q T + S + +M
Sbjct: 866 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM----------------PRV 909
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
KP ++ P ++PE ++ + A ++T+ + + +S+ + SE+ E
Sbjct: 910 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969
Query: 502 AP 503
P
Sbjct: 970 TP 971
Score = 32.0 bits (71), Expect = 3.7
Identities = 50/250 (20%), Positives = 84/250 (33%), Gaps = 22/250 (8%)
Query: 742 PLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEK 801
P+ L P DT SL V + ++ K + ++K A + S EK
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTSAKETQSIEK 181
Query: 802 RSSDS---SSKLAKKRKGEAERDCDNKKIRLEKEIK--SQSSSSSSSHKE-------SSK 849
S+ +SK+ K +AE + KE + +S++ KE S+
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 241
Query: 850 TKPSRPSSQSSKKEMLPPP---------PVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
T P P+ ++K P P ++ ++PA K PK
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
+ T + PK+ + + K + T P P + P KP
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 961 KQQADLHMRE 970
K+ A +E
Sbjct: 362 KEPAPTTPKE 371
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 90.5 bits (223), Expect = 9e-18
Identities = 146/753 (19%), Positives = 268/753 (35%), Gaps = 94/753 (12%)
Query: 192 SAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAV 251
S +E +P +P P P + ++ P T + +K P +PK+ A
Sbjct: 267 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP----APTTTKEPAPT-TPKEPAP 321
Query: 252 KVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELK 311
+ P + AP P P P+ P K K A P ++ P+ E
Sbjct: 322 TTTKEPAPTTTKSAPTTPKE---PAPTTPKKPAPTTPKEPA---PTTPKEPTPTTPKEPA 375
Query: 312 PLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPL 371
P ++ T ++ P K T K P+ + T + T P P
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT---TPKEPAPTTTKEPSPTTPKEPAPT 432
Query: 372 TAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSD 431
T P+T +K P PT S+ T ++ T++K + + +
Sbjct: 433 TTKSAPTT---TKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 432 SEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSD 491
+ + TP++P ++ AP + EP + +A + + ++ + + ++
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 492 SEENEPLETPAPEPEPPT-TNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P E PE PT T + K + P P E P T P P +
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTTPKEPAP 605
Query: 551 ATSQEHSES----------KDPPPKSSSK-APR--APPEAPHPGKRSCQK----SPAQQE 593
T +E + + K+P P + K AP+ AP P +C K +P
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 594 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
P + PK+P + + + T+L +EP P + K+ TKG P +
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTL---KEPA--PTTPKKPAPKELAPTTTKG-PTS 719
Query: 654 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP 713
S++P P P + K P K +PA P T PP
Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPA---------------PTTPETPPP 759
Query: 714 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI 773
+ S + ++ + + SP TP L + T L
Sbjct: 760 TTSEVSTPTTTKEPTTIHK-----------------SPDESTP---ELSAEPTPKALENS 799
Query: 774 PQPPGKGSRQRKAEDK--QPPAGKKHSSEK------RSSDSSSKLAKKRKGEAERDCDNK 825
P+ PG + + A K K ++E+ ++ ++ K+ K+ E+ ++K
Sbjct: 800 PKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 859
Query: 826 KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRS 885
++ S ++ ++ K ++ + ++ K+ + + + ++ AKP + +
Sbjct: 860 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 919
Query: 886 RREADT-CGQDPPKSASSTKSNHKDSSIPKQRR 917
+A T Q P K+ S K ++P+ R+
Sbjct: 920 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 952
Score = 86.7 bits (213), Expect = 1e-16
Identities = 149/739 (20%), Positives = 257/739 (34%), Gaps = 94/739 (12%)
Query: 248 DLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSES 307
D V D T Q + V+ + P T P P S+ P + +
Sbjct: 137 DFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSL-----------PPNSDTSKETSL 183
Query: 308 PELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSW 367
K + ++ T K K T K +QS+E+T + ++ ++L + T
Sbjct: 184 TVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPT--- 239
Query: 368 PPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427
P T P+ P K P PT + S+ + S + + ++
Sbjct: 240 PKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
+ + +++ P AP + + P SA ++ E T+ + + E
Sbjct: 299 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 358
Query: 488 SSSDSEENEPLETPAPEP---EP-PTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRRHP 542
+ + +E P P P EP PTT K +PA P+ P T P P
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPK-----------EPAPTAPKKPAPTTPKEPAP 407
Query: 543 ESKGSSDSATSQEHSES--KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV 600
+ T++E S + K+P P ++ AP E +S +P + P +
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Query: 601 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK 660
PK+P + + + T+ +EP T+ +P T +P EP
Sbjct: 468 APTTPKEPAPTTPKKPAPTT---PKEPA--------PTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 661 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR 720
P P + K P + L+ P K TPE A P T + P +
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKP--APTTPEELA--PTTPEEPTPTTPEEPA 572
Query: 721 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPP-PQSLMVKITLDLLSRIPQPPGK 779
+ + A ++ K+ P ++ +P P P+ + P
Sbjct: 573 PTTPKAAA---PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629
Query: 780 GSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK--SQS 837
+ ++ A + P K E S+ KG A KE +
Sbjct: 630 TTPKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 838 SSSSSSHKESSKTKPSRPSSQSSKKEMLPPP---PVSSSSQKPA-------------KPA 881
++ ++ KE + T P +P+ KE+ P P S++S KPA +PA
Sbjct: 687 GTAPTTLKEPAPTTPKKPAP----KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 882 LKRSRREADTCGQDPPKSAS--STKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP 939
++ A T + PP + S ST + K+ + + S + + +A P
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-----------TIHKSPDESTPELSAEP 791
Query: 940 FPVPSLPNGNSKPGKPQVK 958
P +L N +PG P K
Sbjct: 792 TP-KALENSPKEPGVPTTK 809
Score = 52.8 bits (125), Expect = 2e-06
Identities = 83/437 (18%), Positives = 148/437 (33%), Gaps = 55/437 (12%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAK-SPKDLAVKVHDKET----- 258
P+P P P + + T + P K +PK+LA + T
Sbjct: 595 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654
Query: 259 -PQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY 317
P + P + P P+ P + K TA + P + + P
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 318 RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA-IHT 376
+ T +D P K T P + T E PPP T+ + T
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPPTTSEVST 766
Query: 377 PSTA-EPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS 435
P+T EP+ +S S K + S K T + + ++ + + +
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826
Query: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
P +++A P + + A+ + ES+ T+ + ++ +S+ +++
Sbjct: 827 TERDLRTTPETTTAAPK----MTKETATTTEKTTESKITATT-------TQVTSTTTQDT 875
Query: 496 EP-----LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P L+T P+ TT K +TE + E+ D
Sbjct: 876 TPFKITTLKTTTLAPKVTTTKKTIT------------------TTEIMNKPEETAKPKDR 917
Query: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
AT+ S++ P P+ +KAP+ P P + P P++ T T P
Sbjct: 918 ATN---SKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT-STMPELNPTS 973
Query: 611 ASARAGSRTSLQGEREP 627
A A +T+ + + P
Sbjct: 974 RIAEAMLQTTTRPNQTP 990
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/325 (19%), Positives = 114/325 (35%), Gaps = 47/325 (14%)
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
PK PV A +G + G + D ++ KV T + A P+P++P
Sbjct: 121 PKPPVVDEAGSGL--------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 172
Query: 665 PSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGC 724
P+S+ K S + E N + T +T+
Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTNKQTST------------------DGKEKTTSA 214
Query: 725 RQAVVVQEDSRKD--------RLPLPLRDTKLLSPLRDTP-PPQSLMVKITLDLLSRIPQ 775
++ +++ S KD P P +T P TP P K + P
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 776 PPGKGSRQRKAEDKQPPAGKK-HSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK 834
P S ++ P K ++ K + +++K + K +
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-----EPAP 329
Query: 835 SQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQ 894
+ + S+ ++ KE + T P +P + ++ KE P P + P +PA ++ A T +
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKP-APTTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPK 387
Query: 895 DP----PKSASSTKSNHKDSSIPKQ 915
+P PK + T + PK+
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKE 412
Score = 37.4 bits (85), Expect = 0.087
Identities = 57/302 (18%), Positives = 111/302 (36%), Gaps = 33/302 (10%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
P+P P P + +T P T +S+V + + KSP + ++ + TP+
Sbjct: 741 PAPTTPKKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 798
Query: 265 APAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEK 324
+P +P T P+ + K R + + + +P++ ++T
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT-------KETATT 851
Query: 325 TDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSK 384
T+ +K T ++ S + + T ++ LK T + P T T +T E
Sbjct: 852 TEKTTESKITATTTQVTSTTTQDTTPFKI----TTLKTTTLA-PKVTTTKKTITTTEIMN 906
Query: 385 FPFPT---KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
P T KD S T + Q T + S + +M
Sbjct: 907 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM----------------PRV 950
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
KP ++ P ++PE ++ + A ++T+ + + +S+ + SE+ E
Sbjct: 951 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010
Query: 502 AP 503
P
Sbjct: 1011 TP 1012
Score = 32.0 bits (71), Expect = 3.7
Identities = 50/250 (20%), Positives = 84/250 (33%), Gaps = 22/250 (8%)
Query: 742 PLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEK 801
P+ L P DT SL V + ++ K + ++K A + S EK
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTSAKETQSIEK 222
Query: 802 RSSDS---SSKLAKKRKGEAERDCDNKKIRLEKEIK--SQSSSSSSSHKE-------SSK 849
S+ +SK+ K +AE + KE + +S++ KE S+
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 282
Query: 850 TKPSRPSSQSSKKEMLPPP---------PVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
T P P+ ++K P P ++ ++PA K PK
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
+ T + PK+ + + K + T P P + P KP
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 961 KQQADLHMRE 970
K+ A +E
Sbjct: 403 KEPAPTTPKE 412
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 90.1 bits (222), Expect = 1e-17
Identities = 122/556 (21%), Positives = 208/556 (37%), Gaps = 56/556 (10%)
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
+ S + D ++PEK P SS+ S+P S P+P + +S+ ES + + S
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPS-PQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 488 SSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGS 547
SS S+ + T ++ + + PA G + P + S+
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSR-----RMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
Query: 548 SD----SATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTK 603
S S ++Q S+ P + S++P+ P + R+ Q+ + +R ++
Sbjct: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS---RSRNTQRR-GRSRSARRGRSHSR 565
Query: 604 QPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAV 663
P ++ +R +R R P + S+ + + + R R A +
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPA-------RRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 664 PPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSG-SGSRTS 722
P+ + + +S + S++ S P RTP A + S+ P G S SRT
Sbjct: 619 TPARRRSRTRSPVRRRSRSRS-PARRSGRSRSRTP---ARRGRSRSRTPARRGRSRSRTP 674
Query: 723 GCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSR 782
R + R P ++ +P R +SL+ + SR PQ G+
Sbjct: 675 ARRSG------RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH--SRTPQRRGRSGS 726
Query: 783 QRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS 842
+ ++K + ++ S S+++ +R K RL ++ S SS
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL--SLRRSLSGSSP 784
Query: 843 SHKESSKTKPSRP---SSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQ----- 894
K+ S+T P R SSQ K PP SSS P K K R++ +
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
Query: 895 ---DPPKSASSTKSNHKDSSIPKQRRVEGKG-------SRSSSEH--KGSSGDTANPFPV 942
PP+ S T + S+ QRR + SR+ S H GSS
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 943 PSLPNGNSKPGKPQVK 958
P S +P+VK
Sbjct: 905 PRQSPSRSSSPQPKVK 920
Score = 89.4 bits (220), Expect = 2e-17
Identities = 194/870 (22%), Positives = 307/870 (35%), Gaps = 87/870 (10%)
Query: 127 GNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHK-KGDRRADGDH 185
G+ S +P RT P S C +S+ L R G S K K + H
Sbjct: 932 GSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP--RYSHSGSSSPDTKVKPETPPRQSH 989
Query: 186 CASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCP--- 242
S+ SP + + PP + ++ P+ + + S S C
Sbjct: 990 SGSI---------SPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040
Query: 243 -AKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQD 301
+ P + V + S +P S T P S S + + + P G+
Sbjct: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHR-SDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
Query: 302 QAPSESPEL---KPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV---HC 355
++ S EL P+ +D R + LK + ++ + S S SN +
Sbjct: 1100 RSSSPVTELASRSPIRQD-RGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSR 1158
Query: 356 VEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNS 415
+E + + PP A +P + PFP +D S V ++ + ++ + S
Sbjct: 1159 LETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGS 1218
Query: 416 QQGTSSMLEDDLQLSDSEDSDSEQTPEKP--PSSSAPPSAPQSLPEPVASAHSSSAESES 473
T ++ + S+D + + EK P+ L E S SS E E
Sbjct: 1219 SPETKE--QNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEE 1276
Query: 474 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPE--- 530
+ D +S ++ E + + P +K +L N + + +P E
Sbjct: 1277 RPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHK-ELSNSPLRENSFGSPLEFRN 1335
Query: 531 -GPRSTE---------------PPRRHPESKGSSD----SATSQEHSESKDPPPK----- 565
GP TE P E+ S D S S HS S+ P
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAG 1395
Query: 566 -SSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQ-G 623
SS+++ +P P S ++S + P + + P+ P + S R+GS L+ G
Sbjct: 1396 MSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL----PRTPSRRS-RSGSSPGLRDG 1450
Query: 624 EREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKAL 683
P KD P+ ++GR +S EPK A+P + + S P +
Sbjct: 1451 SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK-ALPQTPRPRSRSPSSPELNNKC 1509
Query: 684 SGPEPAKDNVEDRTPEH-FALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLP 742
P+ + E + A PL + SGS S+ + + QE S D P
Sbjct: 1510 LTPQRERSGSESSVDQKTVARTPLGQRS---RSGS-SQELDVKPSASPQERSESDSSPDS 1565
Query: 743 LRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKR 802
T+ +PLR S +D SR+ + + +DK P A + S
Sbjct: 1566 KAKTR--TPLRQRSRSGS---SPEVDSKSRLSPRRSRSGSSPEVKDK-PRAAPRAQSGSD 1619
Query: 803 SSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKT--KPSRPSSQSS 860
SS A + R + K R S S+ SS H S+T + SR S +
Sbjct: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK 1679
Query: 861 KKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDS---SIP---- 913
K PP SS S + SRR P++ S T H+ S S P
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKARLSRRSRS--ASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
Query: 914 KQRRVEGKGSRSSSEHKGSSGDTANPFPVP 943
K R + S SS K +S +P P P
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
Score = 89.4 bits (220), Expect = 2e-17
Identities = 203/961 (21%), Positives = 337/961 (35%), Gaps = 205/961 (21%)
Query: 93 PLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCG 152
P GSS P + + H+ G+IS PK+ + +T P PSL
Sbjct: 965 PRYSHSGSSSPDTKVKPETPPRQSHS--------GSISPYPKV-KAQTPPGPSLSGSKS- 1014
Query: 153 PPDSQHLTQDRL--------------------GQEGFG-SSHHKKGDRRADGDHCASVTD 191
P Q ++D L G+ FG SS KG + DH +
Sbjct: 1015 -PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT-- 1071
Query: 192 SAPE------------------------RELSPLISLPS--PV----------PPLSPIH 215
S+PE R SP+ L S P+ P L
Sbjct: 1072 SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGM 1131
Query: 216 SNQQTLPRTQGSSKVHGSSNNSKGYC---PAKSPKDLAVKVHDKETPQDSLVAPAQPPSQ 272
S +Q+ ++ SS SN+ G A+S + +A+ PQ+ A A PP Q
Sbjct: 1132 SPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALP------PQED--ATASPPRQ 1183
Query: 273 T-----FPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP----EDYRQQTFE 323
FP P S+ + R G +P + LP ++ + E
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243
Query: 324 KTDLKVPAKAKLTKL-----KMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPS 378
K++ PA L+ L +M + + E + E + + + S L A+ PS
Sbjct: 1244 KSE--EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQS-QASLEAVEVPS 1300
Query: 379 TAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGT------SSMLEDDLQLSDS 432
A P + + + +S+ + + + + ++ GT SS +++DL
Sbjct: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN---- 1356
Query: 433 EDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDS 492
P Q +P S S S S+ S D+ ++ S
Sbjct: 1357 -----------------GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSS- 1398
Query: 493 EENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSD-SA 551
N+ + +P + P T ++ + + S P PR+ R S G D S
Sbjct: 1399 --NQSISSPVLDAVPRTPSRERSSS----ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSG 1452
Query: 552 TSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKP--- 608
T HS S SS + P P G+ C SP + PQ ++ P P
Sbjct: 1453 TPSRHSLS------GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELN 1506
Query: 609 ----VKASARAGSRTSLQGEREPGLLPYGSRDQT-SKDKPKVKTKGRPRAAASNEPKPAV 663
R+GS +S+ ++ P G R ++ S + VK P+ + ++
Sbjct: 1507 NKCLTPQRERSGSESSVD-QKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD----- 1560
Query: 664 PPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSG 723
SS K K+ P ++ SG P D+ +P E + P + +++
Sbjct: 1561 --SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS 1618
Query: 724 CRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQ 783
DS SP P P++L + S+ P +GS
Sbjct: 1619 ---------DS---------------SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 784 RKAEDKQPPAGKKHSSEKRSSD---SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS 840
++ + PP + RSS + S+ +R+ +K RL + +S SSS
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 841 SSS------HKES---SKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALK-------- 883
+ H+ S S +P+ S S ++ P ++S++ P+ K
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 884 -RSRREADTCGQDPPKSASSTKSNHK-----DSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
RSRRE + +S SS ++ + S +RR G G S S + S T+
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 938 N 938
+
Sbjct: 1835 S 1835
Score = 88.2 bits (217), Expect = 4e-17
Identities = 205/976 (21%), Positives = 353/976 (36%), Gaps = 121/976 (12%)
Query: 18 REKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKE---FLSTK 74
R+K++ + Q++ PE +F + +T R ++ G+ E KE L T
Sbjct: 1182 RQKDKFSPFPVQDR---PESSLVFKDTLRTPP------RERSGAGSSPETKEQNSALPTS 1232
Query: 75 SHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPK 134
S L + +P ++ S + S TS S +S+ + +
Sbjct: 1233 SQDEELMEVVEKSEEPAGQILSHLSSELKEMS--TSNFESSPEVEERPAVSL-TLDQSQS 1289
Query: 135 MAQPRTEPMPSLHAKSCGP---PDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTD 191
A +PS+ + GP P+ + L+ L + FGS + + +
Sbjct: 1290 QASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSS 1349
Query: 192 SAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAV 251
E P ++ P L Q T SS++ + G S + ++
Sbjct: 1350 EVKEDLNGPFLNQLETDPSLDM--KEQSTRSSGHSSSELSPDAVEKAGM---SSNQSISS 1404
Query: 252 KVHDK--ETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPS---E 306
V D TP + A P P PS+ P +R G S
Sbjct: 1405 PVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPG--LRDGSGTPSRHSLSGS 1462
Query: 307 SPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHS 366
SP +K +P + E D KA + S+S N + + + S
Sbjct: 1463 SPGMKDIPRTPSRGRSE-CDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSES 1521
Query: 367 WPPPLTAIHTP---STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS----NSQQGT 419
T TP + S K S +++ D+ +KT + S+ G+
Sbjct: 1522 SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS 1581
Query: 420 SSMLEDDLQLSD--SEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASA-HSSSAESESTSD 476
S ++ +LS S S + +KP ++ S S PEP A A + S S S
Sbjct: 1582 SPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641
Query: 477 SDSSSDSESESSSSDSEENEPLET--------PAPEPE-----PPTTNKWQLDNWLTKV- 522
S S SSS++S P ++ +PEP+ PP + LT+
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701
Query: 523 -----SQPAAPPEGPRSTEPPRRHPESKGSSD-----SATSQEHSESKDPPPKSSSKAPR 572
S+ A+ RS PPR SS S +S+ + P K++S+ R
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 573 APPEAPHPGKRSCQKSPAQQEPPQRQTV------GTKQPKKPVKASARAGSRTSLQGERE 626
+P P R Q+S ++ + +T G+ Q + +R+ SR + R
Sbjct: 1762 SPSPKP----RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVT---RRR 1814
Query: 627 PGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAP-SKALSG 685
G Y SR ++ + ++ R + PP+S K+ + PAP ++ S
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRR-------RGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
Query: 686 PEPAKD-NVEDRTP------EHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDR 738
PA RTP P++ + + R S R + V + SR
Sbjct: 1868 ASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRT 1927
Query: 739 LPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHS 798
P+ R ++ +P T SR PP +R++ + PP ++
Sbjct: 1928 PPVTRRRSRSRTP--------------TTRRRSRSRTPP---VTRRRSRSRTPPVTRRR- 1969
Query: 799 SEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKES-SKTKPSRPSS 857
S R+S + + ++ R R + +S+S +S + + S S+T P+
Sbjct: 1970 SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR 2029
Query: 858 QSSKKEMLPPPPVSSSS----QKPAKPALKRSRREADTCGQDPP----KSASSTKSNHKD 909
S+ +LP S S ++ ++ R+ R + + PP +SAS + S+
Sbjct: 2030 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSR 2089
Query: 910 SSIPKQRRVEGKGSRS 925
S+ P R GSR+
Sbjct: 2090 SATPPATR-NHSGSRT 2104
Score = 85.1 bits (209), Expect = 4e-16
Identities = 194/904 (21%), Positives = 324/904 (35%), Gaps = 161/904 (17%)
Query: 137 QPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEG--------FGSSHHKKGDRRADGDHCAS 188
Q + P KS PP +T + ++ F SS + R H S
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 189 ------VTDSAPERELSPLISLPSP-----VPPLSPIHSNQQTLPRTQGSSKVHGSSNNS 237
V S P R+ S P P + P HS + ++ +S+ + S
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 238 KGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPM 297
C + L H + D+ V P PP Q+ P V Q P
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPP------- 1005
Query: 298 DGQDQAPSESPELKPLPEDYRQQTFEKT---DLKVPAKAK-----------LTKLKMPSQ 343
PS S P P++ + + ++ L + A K ++ L++ Q
Sbjct: 1006 -----GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQ 1060
Query: 344 SVEQTYSNEVHCVEEILKEMTHSWPPPL-TAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQ 402
S QT + +HS P L + T S+ P + S + Q++
Sbjct: 1061 S--QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDR 1118
Query: 403 KQYDTS-------SKTHSNSQQGTSSMLEDD----LQLSDSEDSDSEQTPEKPPSSSAPP 451
++ S S S Q +SS D L S E ++S++ PP A
Sbjct: 1119 GEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA 1178
Query: 452 SAPQS----LPEPVASAHSSSAESEST--------SDSDSSSDSESESSS--SDSEENEP 497
S P+ P PV SS + T S + SS +++ ++S+ + S++ E
Sbjct: 1179 SPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEEL 1238
Query: 498 LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHS 557
+E EP L + L ++S S+ P + D + SQ
Sbjct: 1239 MEVVEKSEEPAGQILSHLSSELKEMS-----TSNFESSPEVEERPAVSLTLDQSQSQASL 1293
Query: 558 ESKDPPPKSSS-KAPRAPPE----APHPGKRSCQKSPAQ--QEPPQRQTVGT-------- 602
E+ + P +SS P PE + P + + SP + P + T
Sbjct: 1294 EAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKE 1353
Query: 603 ----------------KQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDK-PKV 645
++ ++S + S S + G+ S D P+
Sbjct: 1354 DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT 1413
Query: 646 KTKGRPRAAASNEPKPAVPPSSEKKKHKSSLP-------APSK-ALSGPEPAKDNVEDRT 697
++ R +A+S E K +P + ++ S P PS+ +LSG P +
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD----- 1468
Query: 698 PEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLP-LPLRDTKLLSPLRDTP 756
+P T S+G S + Q + R P P + K L+P R+
Sbjct: 1469 ------IPRTPSRGRSECDSSPEPK-----ALPQTPRPRSRSPSSPELNNKCLTPQRERS 1517
Query: 757 PPQSLMVKITLDLLSRIPQPPGKGSRQRKAE--DKQPPAGKKHSSEKRSSDSSSKLAKKR 814
+S ++D + P G+ SR ++ D +P A + SE SS S +
Sbjct: 1518 GSES-----SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP 1572
Query: 815 KGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSS 874
+ R + ++ + + + S S SS + K + + P +QS S SS
Sbjct: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR-AAPRAQSG----------SDSS 1621
Query: 875 QKPAKPA----LKRSRREADTCGQDP-PKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
+P PA +RSR + + G+ P P+ +SST+S+ + P + R +GSRSS E
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH---PPKSRTARRGSRSSPEP 1678
Query: 930 KGSS 933
K S
Sbjct: 1679 KTKS 1682
Score = 82.8 bits (203), Expect = 2e-15
Identities = 187/852 (21%), Positives = 290/852 (34%), Gaps = 152/852 (17%)
Query: 170 GSSHHKKGDRRADGDHCASVTDS-APERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSS 228
G S RR +GD S + + +R SP + P P +++ T+ S
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352
Query: 229 KVHGSSNNSKGYCPAK--------SPKDLAVKVHDKETPQDSLVAPAQPPSQTFP----- 275
SS + P SP+ LA +E P PPS+ P
Sbjct: 353 SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE--------PVNPPSEASPTRDRS 404
Query: 276 ----PPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPA 331
P LP S + P+ + + ESP+ P P +R+
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE------------ 452
Query: 332 KAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAE--PSKFPFPT 389
S T N H + K +H+ + +P+TA+ S+ PT
Sbjct: 453 -----------ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 390 KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA 449
K S Q ++ S S Q S S T + S SA
Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSP----QRPGWSRSRNTQRRGRSRSA 557
Query: 450 PPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSD-----SEENEPLETPAPE 504
S P S S S S + + S S S P
Sbjct: 558 RRGRSHS-RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR 616
Query: 505 PEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPP 564
P + + + + + S+ +P RS R P +G S S T S+ P
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPAR--RSGRSRSRTPARRGRSRSRTPARRGRSRSRTP 674
Query: 565 -----KSSSKAP--------RAPPEAPHPGKRSCQKSPAQQEPPQRQ-TVGTKQPKKPVK 610
+S S+ P R P + ++ + PQR+ G+ +K
Sbjct: 675 ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 611 ASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGR-------------PRAAASN 657
+++ SR++ E + + SR S P+ K K R P+ +
Sbjct: 735 RTSQRRSRSNSSPEMKKSRI--SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
Query: 658 EPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALV--PLTESQGPPHS 715
P+ + SS+ K + P S++ S P P + + H + P +S PP
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
Query: 716 GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLR-------------DTPPPQSLM 762
GS + Q+V Q S + P P + K +P R TPP QS
Sbjct: 853 GSITSPQANEQSVTPQRRSCFESSPDP--ELKSRTPSRHSCSGSSPPRVKSSTPPRQS-- 908
Query: 763 VKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKK---RKGEAE 819
P S Q K + P + HS SS S S++ + R+ +
Sbjct: 909 -------------PSRSSSPQPKVKAIISPRQRSHSGS--SSPSPSRVTSRTTPRRSRSV 953
Query: 820 RDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAK 879
C N + RL + S S SSS +K KP P QS + P P V +Q P
Sbjct: 954 SPCSNVESRL---LPRYSHSGSSS--PDTKVKPETPPRQSHSGSISPYPKV--KAQTPPG 1006
Query: 880 PALKRSR------READTCGQDPPKSASSTKSNHKDSSIPKQ-----RRVEGKG-SRSSS 927
P+L S+ + D+ Q P S S + K S+ P + ++ KG S++S
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLC-AGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065
Query: 928 EHKGSSGDTANP 939
+H+ DT++P
Sbjct: 1066 DHR---SDTSSP 1074
Score = 76.6 bits (187), Expect = 1e-13
Identities = 113/499 (22%), Positives = 185/499 (37%), Gaps = 76/499 (15%)
Query: 198 LSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKE 257
L+ L S PP + + + P+ S+ + G P + V +
Sbjct: 2306 LAALSLTGSGTPPTAANYPSSSRTPQAPASANLVG---------PRSAHATAPVNIAGSR 2356
Query: 258 TPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY 317
T + +APA S P +L ++ + P + + G+ P
Sbjct: 2357 TA--AALAPASLTSARMAP-ALSGANLTSPRVPLSAYERVSGRTSPP------------L 2401
Query: 318 RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTP 377
+ +T P+++++T + PS S + + + S PP A P
Sbjct: 2402 LDRARSRTPPSAPSQSRMTSERAPSPS------------SRMGQAPSQSLLPP--AQDQP 2447
Query: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
+ PS F Q + Q + S + TSS + + LS
Sbjct: 2448 RSPVPSAF-----SDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 438 EQTPEKPPSSSAP--PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
+PP+S+ PSA +L +P SSS+ S S+S S SSS S S SSSS S +
Sbjct: 2503 HSDVGEPPASTGAQQPSALAAL-QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 496 EPLETPAP-EPEPPTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRRHP----------- 542
+ + P +PE L +V P AP E R PP P
Sbjct: 2562 DSEGSSLPVQPEVA----------LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
Query: 543 -----ESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQR 597
S SS S++S S S SSS + + P PG ++ K + ++PP
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 598 QTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKG-RPRAAAS 656
+ ++ P+KP+ + + S + ER RDQ S + +G R + +
Sbjct: 2672 ER-RSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Query: 657 NEPKPAVPPSSEKKKHKSS 675
+ + PS +H+SS
Sbjct: 2731 SHKRRRETPSPRPMRHRSS 2749
Score = 74.3 bits (181), Expect = 6e-13
Identities = 135/665 (20%), Positives = 236/665 (35%), Gaps = 75/665 (11%)
Query: 299 GQDQAPSESPELKPLPEDYRQQ---TFEKTDLKVPAKA-----KLTKLKMPSQSVEQTYS 350
GQ A +E+ +L L E ++ F +D V + + + K P+ + YS
Sbjct: 113 GQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS 172
Query: 351 NEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSK 410
+++E + S P TP + K KD S + +++ SSK
Sbjct: 173 --------LVRESSSSRSP------TPKQKKKKK----KKDRGRRSESSSPRRERKKSSK 214
Query: 411 THSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAE 470
+ + S + S+ ++ ++ S++ P + ++ A + SSS
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 471 SESTSDSDSSSDSESESS--SSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAP 528
S S S S ++ + + S E AP EP TT+ + + T QP++P
Sbjct: 275 SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
Query: 529 PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKS 588
E D ++ + P P+ SS PE P P ++
Sbjct: 335 YE----------------DKDKDKKEKSATRPSPSPERSSTG----PEPPAPTPLLAERH 374
Query: 589 PAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTK 648
+P T ++PV + A + P LP S ++S P+
Sbjct: 375 GGSPQP----LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKV 430
Query: 649 GRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEH---FALVP 705
R +++ PKPA P S ++ SS P SK S +D TP + P
Sbjct: 431 SRHASSSPESPKPAPAPGSHRE--ISSSPT-SKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487
Query: 706 LTESQGPPHSGSGSRTSGCRQAVVVQEDSRK----DRLPLPLRDTKLLSPLRDTPPPQSL 761
T +G S + ++ R SR R P R + SP R
Sbjct: 488 ATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN 547
Query: 762 MVKITLDLLSRIPQPPGKGSRQRKAEDKQPPA--GKKHSSEKRSSDSSSKLAKKRKGEAE 819
+ +R + + R + PA G+ S S S+ +R+ +
Sbjct: 548 TQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR 607
Query: 820 RDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAK 879
+ R + +S + S + S P+R S +S + P S S+ PA+
Sbjct: 608 TPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS--RSRTPARRGRSRSRTPAR 665
Query: 880 PALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRV-------EGKGSRSSSEHKGS 932
RSR A G+ +S + + S P++ R G+ + + +G
Sbjct: 666 RGRSRSRTPARRSGRS--RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR 723
Query: 933 SGDTA 937
SG ++
Sbjct: 724 SGSSS 728
Score = 72.4 bits (176), Expect = 2e-12
Identities = 99/438 (22%), Positives = 154/438 (35%), Gaps = 65/438 (14%)
Query: 532 PRSTEPPRRHPESKGSSDSA-----TSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQ 586
P S R P G++ ++ ++ E + PP R PP AP + + +
Sbjct: 2363 PASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSE 2422
Query: 587 KSPAQ-----QEPPQRQTVGTK-QPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSK 640
++P+ Q P Q + QP+ PV ++ SR L + P GS+ +S
Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRC-LIAQTTPVA---GSQSLSSG 2478
Query: 641 DKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEH 700
+ + P P VP S + S+ AL+ +PAK+ +
Sbjct: 2479 AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS--- 2535
Query: 701 FALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQS 760
+ S S S S +S + DS LP+ P+
Sbjct: 2536 ------SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ---------------PEV 2574
Query: 761 LMVKITLDLLSRIPQP---PGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGE 817
L R+P P P + R+ + + P K+ SS SS SSS +
Sbjct: 2575 A--------LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Query: 818 AERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLP--PPPVSSSSQ 875
+ + S SSSSSSS SS P++P Q+ K P PPP S+
Sbjct: 2627 SSSSSSSS---------SSSSSSSSS-SSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Query: 876 KPAKPALKRSRREADTCGQDP-PKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSG 934
P KP S R++ + P + S + + +D R +G R S
Sbjct: 2677 SPRKPI--DSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734
Query: 935 DTANPFPVPSLPNGNSKP 952
P P P + P
Sbjct: 2735 RRETPSPRPMRHRSSRSP 2752
Score = 72.0 bits (175), Expect = 3e-12
Identities = 87/364 (23%), Positives = 134/364 (36%), Gaps = 35/364 (9%)
Query: 262 SLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQT 321
S P+ P PS S M Q P+ + P P++ P+P + Q+
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLP-------PAQDQPRSPVPSAFSDQS 2459
Query: 322 FEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHS---WPPPLTAIHTPS 378
P + + + + + + HS PP T PS
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519
Query: 379 TAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSE 438
+ P K+ + SS + + +SS + S+S SS SDSE S
Sbjct: 2520 ALAALQ---PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS-------SDSEGSSLP 2569
Query: 439 QTPEK-----PPSSSAPPSAPQS--LPEPVASAH---SSSAESESTSDSDSSSDSESESS 488
PE P + AP A + PEP + SSS+ S S+S S SSS S S SS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 489 SSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSS 548
SS S + + + P+ K L K + P PP G R + PR+ +S S
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAK-PGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 549 DSAT-SQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPA---QQEPPQRQTVGTKQ 604
S + S P P + + G+R +SP+ ++E P + + +
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Query: 605 PKKP 608
+ P
Sbjct: 2749 SRSP 2752
Score = 70.5 bits (171), Expect = 9e-12
Identities = 119/536 (22%), Positives = 183/536 (34%), Gaps = 80/536 (14%)
Query: 440 TPEKPPSSSAPPSAPQ--SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEP 497
T PPS SA A + +P PV +A + + + ++ + + + +S P
Sbjct: 2192 TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIP 2251
Query: 498 LETP-APEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEH 556
A P L + T V+ A PR+ P + + + +
Sbjct: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311
Query: 557 SESKDPPPK----SSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKAS 612
+ S PP SSS+ P+AP A G RS + R
Sbjct: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM 2371
Query: 613 ARAGSRTSLQGEREPGLLPYGSRDQTS-KDKPKVKTKGRPRAAASNEPKPAVPPSSEKKK 671
A A S +L R +P + ++ S + P + + R R P+ P S
Sbjct: 2372 APALSGANLTSPR----VPLSAYERVSGRTSPPLLDRARSRTP------PSAPSQSRMTS 2421
Query: 672 HKSSLP------APSKALSGPEPAKDNVEDRTPEHFA-LVPLTESQGPPHSGSGSRTSGC 724
++ P APS++L PA+D P F+ +Q P +GS S +SG
Sbjct: 2422 ERAPSPSSRMGQAPSQSLL--PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479
Query: 725 RQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQR 784
L +P P D P P G++Q
Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGV----PHSDVGEP-----------------PASTGAQQP 2518
Query: 785 KAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSH 844
A PA ++ SS SS SSS + S SSS SSS
Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSS-----------------SSSSSGSSSS 2561
Query: 845 KESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKP----ALKRSRREADTCGQDPPKSA 900
+ P +P + + K + P P + + +P KR RR + + S+
Sbjct: 2562 DSEGSSLPVQP--EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQ 956
SS+ S+ SS S SSS SS +++P P P KP P+
Sbjct: 2620 SSSSSSSSSSS---------SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Score = 64.7 bits (156), Expect = 5e-10
Identities = 122/499 (24%), Positives = 181/499 (36%), Gaps = 90/499 (18%)
Query: 531 GPRSTEPPRRHPESKGSSD----SATSQEHSESKDPPPKSSSK----------APRAPPE 576
G + P+R S SS+ S TSQ S S P S+ +PR+ +
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
Query: 577 APHPGKRSCQKS---PAQ--QEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLP 631
+ +RS S P Q Q PP+R G+ QPK + R +S ++ P
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Query: 632 YGSRDQTSKDKPKVKTKGRPRAAASNEP---KPAVPP---------------SSEKKKHK 673
+S PKVK+ PR + P + +V P S +H
Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890
Query: 674 SSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSG--------SRTSGCR 725
S +P + S P + +P+ ++ Q HSGS SRT+ R
Sbjct: 891 CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ-RSHSGSSSPSPSRVTSRTTPRR 949
Query: 726 QAVVVQEDSRKDRLPLPLRDTKLLSP----LRDTPPPQSLMVKITLDLLSRIPQPPG--- 778
V + + RL + SP +TPP QS I+ + PPG
Sbjct: 950 SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009
Query: 779 KGSR----QRKAEDKQPP---------AGKKHSS---EKRSSDSSSKLAKKRKGEAERDC 822
GS+ Q K++D AG K S+ E SS +L KG+++
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQL----KGQSQTSP 1065
Query: 823 DNKKIRLEKEIKSQSSSSSSSHKESSKTKP--SRPSSQSSKKEMLPPPPV-SSSSQKPAK 879
D++ E++ QS S S S + S+T P R S S E+ P+ + A
Sbjct: 1066 DHRSDTSSPEVR-QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Query: 880 PALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA-- 937
P LK + Q S + SN S+ Q R+E S+ TA
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSN----SLLGQSRLETAESKEKMALPPQEDATASP 1180
Query: 938 -------NPFPVPSLPNGN 949
+PFPV P +
Sbjct: 1181 PRQKDKFSPFPVQDRPESS 1199
Score = 62.0 bits (149), Expect = 3e-09
Identities = 85/355 (23%), Positives = 136/355 (38%), Gaps = 66/355 (18%)
Query: 595 PQRQTVGTKQPK-KPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
PQR+ KQP +P K + +S SR T K K K K K R R
Sbjct: 153 PQRRAREAKQPAPEPPKPYSLVRESSS-------------SRSPTPKQKKKKKKKDRGRR 199
Query: 654 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEP--AKDNVEDRTPEHFALVPLTESQG 711
+ S+ P+ SS+KKKH+S + + P P + + + + + P +S+
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR 259
Query: 712 PPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLS 771
S S S D+ + R T T L
Sbjct: 260 AHRSTSADSAS--------SSDTSRSRSRSAAAKTH------------------TTALAG 293
Query: 772 RIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEK 831
R P P + R+ E P + +S +R SS + A K+ D D +K
Sbjct: 294 RSPSP----ASGRRGEGDAPFSEPGTTSTQR--PSSPETATKQPSSPYEDKDK-----DK 342
Query: 832 EIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSS--SQKPAKPALKRSRREA 889
+ KS + S S + S+ +P P+ +++ P P++++ SQ+P P + S
Sbjct: 343 KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEAS---- 398
Query: 890 DTCGQDPPKSASS-TKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVP 943
T + PPKS +S+ +SS P + + S H SS ++ P P P
Sbjct: 399 PTRDRSPPKSPEKLPQSSSSESSPPSPQPTK------VSRHASSSPESPKPAPAP 447
Score = 59.7 bits (143), Expect = 2e-08
Identities = 83/345 (24%), Positives = 126/345 (36%), Gaps = 36/345 (10%)
Query: 430 SDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSS-----AESESTSDSDS-SSDS 483
S+ S S + + P S PP+ Q PV SA S A++ + S S SS +
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPR-SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479
Query: 484 ESESSSSDSEENEPLETPAPEP------EPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP 537
+ ++SS + N L PAP EPP + Q + L + QPA
Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL-QPAKE--------- 2529
Query: 538 PRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQR 597
RR S SS S++S S S SS + P + + ++ P+ P +
Sbjct: 2530 -RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP-K 2587
Query: 598 QTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASN 657
+ V +P +P A + S +S S +S + +++S+
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 658 EPKPAVP-PSSEKKKHKSSLPAPSKALS-GPEPAKDNVEDRTPEHFALVPLTESQGPP-- 713
P PA P P + K P P + S P D++ D ++ V P
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 714 ---HSGSGSRTSGCRQAVVVQEDSRKDR----LPLPLRDTKLLSP 751
S S R S Q + S K R P P+R SP
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 50.4 bits (119), Expect = 1e-05
Identities = 166/792 (20%), Positives = 266/792 (33%), Gaps = 99/792 (12%)
Query: 386 PFPTKDSQHVSSVTQNQKQYDTS--SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP-- 441
P + S+ +SVT+ + + S S+ S S+ + + + +TP
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
Query: 442 -EKPPSSSAPPSA---PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEP 497
+ S PP +S P+ S S S T S S S S +
Sbjct: 1954 TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPV 2013
Query: 498 LETPAPEPEPPTTNKWQ------LDNWLTKVSQPAAPPEGPRSTEP---------PRRHP 542
+ PP + L ++ P A RS P R P
Sbjct: 2014 TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPP 2073
Query: 543 ESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPP--QRQTV 600
+ S S +S + S S PP + R PP A + + SC P+ P + ++
Sbjct: 2074 AIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSP 2133
Query: 601 GTKQP----KKPVKASARA-GSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAA 655
G +P + P+ +A GS G R P +TS + +++ A
Sbjct: 2134 GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP------DHQRTSVPENHAQSRIALALTA 2187
Query: 656 SNEPKPAVPPSSEK---KKHKSSLPAPSKALSGPEPAKDNVEDRTP-EHFALVPLTESQG 711
+ PPS S +PAP +S N+ R P A + L ++
Sbjct: 2188 ISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASART 2247
Query: 712 PPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLL- 770
P + + A + R + L P T P +L T L
Sbjct: 2248 PAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALA 2307
Query: 771 -------------------SRIPQPPGK----GSRQRKAEDKQPPAGKKHSSE-KRSSDS 806
SR PQ P G R A AG + ++ +S +
Sbjct: 2308 ALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLT 2367
Query: 807 SSKLAKKRKGEAERDCDNKKIRLEK-EIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEML 865
S+++A G + + ++ L E S +S + S+T PS P SQS
Sbjct: 2368 SARMAPALSG---ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP-SQSRMTSER 2423
Query: 866 PPPPVSSSSQKPAKPALKRSRREADTCGQDPPKS-ASSTKSNHKDSSIPKQRRVEGKGSR 924
P P S Q P++ L + QD P+S S S+ I + V G S
Sbjct: 2424 APSPSSRMGQAPSQSLLPPA--------QDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL 2475
Query: 925 SS---SEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQ--ADLHMREAKKMKQKAE 979
SS + S+GD VP+ +S G+P QQ A ++ AK+ + +
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535
Query: 980 LMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDAT 1039
+ + ++ S S SS S+ S S++ + +
Sbjct: 2536 SSSSSSSSS---------------SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580
Query: 1040 APTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIASTG 1099
+PT AV R R + S + + SSS + + S +S+
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1100 TPSPLSPMPSPA 1111
+ S S PSPA
Sbjct: 2641 SSSSSSSSPSPA 2652
Score = 31.6 bits (70), Expect = 4.8
Identities = 48/222 (21%), Positives = 73/222 (32%), Gaps = 24/222 (10%)
Query: 100 SSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQ---PRTEPMPSLHAKSCGPPDS 156
SS SSS +S S +S ++ P++A P P P + PP+
Sbjct: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP 2598
Query: 157 QHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHS 216
+ R SS + +S + S+ S S SP SP
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP----SPAKP 2654
Query: 217 NQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPP 276
Q LP+ K S +SP+ + D + S V +P Q P
Sbjct: 2655 GPQALPKPASPKKPPPGERRS------RSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 277 PSLPSKSVAMQQKPTAYVRPMDGQDQAPS-----ESPELKPL 313
S S + R G ++PS E+P +P+
Sbjct: 2709 DQQSSSSERGSR------RGQRGDSRSPSHKRRRETPSPRPM 2744
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 89.4 bits (220), Expect = 2e-17
Identities = 159/801 (19%), Positives = 277/801 (34%), Gaps = 111/801 (13%)
Query: 216 SNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA--------VKVHDKETPQDSLVAPA 267
+ + ++ Q SS SS++S KS K+ A +KV D + +
Sbjct: 114 TEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 173
Query: 268 QPP--------------SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPL 313
+PP T P S + +P++ + P S K
Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 233
Query: 314 PEDYRQQTFEKT--------DLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTH 365
++T +T K K T K +QS+E+T + ++ ++L + T
Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPT- 291
Query: 366 SWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLED 425
P T P+ P K P PT + S+ + S + + ++
Sbjct: 292 --PKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 426 DLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSES 485
+ + +++ P AP + + P SA ++ E T+ + +
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 486 ESSSSDSEENEPLETPAPEP---EP-PTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRR 540
E + + +E P P P EP PTT K +PA P+ P T P
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-----------EPAPTAPKKPAPTTPKEP 457
Query: 541 HPESKGSSDSATSQEHSES--KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQ 598
P + T++E S + K+P P ++ AP E +S +P + P +
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517
Query: 599 TVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNE 658
PK+P + + + T+ +EP T+ +P T +P E
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTT---PKEPA--------PTTPKEPAPTTTKKPAPTTPKE 566
Query: 659 PKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSG 718
P P P + K P + L+ P K TPE A P T + P +
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP--APTTPEELA--PTTPEEPTPTTPEE 622
Query: 719 SRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPP-PQSLMVKITLDLLSRIPQPP 777
+ + A ++ K+ P ++ +P P P+ + P
Sbjct: 623 PAPTTPKAAA---PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 778 GKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK--S 835
+ ++ A + P K E S+ KG A KE +
Sbjct: 680 APTTPKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 736
Query: 836 QSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP---PVSSSSQKPA-------------K 879
++ ++ KE + T P +P+ KE+ P P S++S KPA +
Sbjct: 737 PKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792
Query: 880 PALKRSRREADTCGQDPPKSAS--STKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
PA ++ A T + PP + S ST + K+ + + S + + +A
Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-----------TIHKSPDESTPELSA 841
Query: 938 NPFPVPSLPNGNSKPGKPQVK 958
P P +L N +PG P K
Sbjct: 842 EPTP-KALENSPKEPGVPTTK 861
Score = 75.1 bits (183), Expect = 4e-13
Identities = 178/880 (20%), Positives = 308/880 (35%), Gaps = 127/880 (14%)
Query: 81 DASENRLGK---PKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQ 137
D +NR K PK P++ + GS + + F + TP + +S +PK+
Sbjct: 161 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDF-------KVTTPDTSTTQHNKVSTSPKITT 213
Query: 138 PRT-EPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPE- 195
+ P PSL S D+ T + +E + + T SA E
Sbjct: 214 AKPINPRPSLPPNS----DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 269
Query: 196 --------RELSP---LISLPSPV-------PPLSPIHSNQQTLPRTQGSSKVHGSSNNS 237
++L+P +++ P+P P L+ T P+ S+ + +
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329
Query: 238 KGYCPAKSPKDLAVKVHDKE--TPQDSLVAPAQPPSQTFPPPSLPSKS-----VAMQQKP 290
P +PK+ A TP++ + P+ T P P+ + + P
Sbjct: 330 IKSAPT-TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388
Query: 291 TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS 350
T P + P+ + +P P ++ T T K PA TK P+ E +
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPT--TKEPAPTTPKEPAPT 444
Query: 351 NEVHCVEEILKEMTHSWP--PPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTS 408
KE + P P T PS P K P PT + T + T+
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-KEPAPTTTKS--APTTTKEPAPTTT 501
Query: 409 SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVAS----- 463
+ ++ + + ++ + E + + TP+KP ++ AP + EP +
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPT--TPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Query: 464 AHSSSAESESTSDSDSSSDSESESSSSDSEENEPL--ETPAP------------EPEP-- 507
A ++ E T+ +++ + + + + E+ P E PAP EP P
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 508 -----PTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSES--K 560
PTT K N K P P E P T P P + + T + + + K
Sbjct: 620 PEEPAPTTPKAAAPN-TPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677
Query: 561 DPPPKSSSK-APR--APPEAPHPGKRSCQK----SPAQQEPPQRQTVGTKQPKKPVKASA 613
+P P + K AP+ AP P +C K +P P + PK+P +
Sbjct: 678 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 737
Query: 614 RAGSRTSLQGE-----REPG---LLPYGSRDQTS--KDKPKVKTKGR-----PRAAASNE 658
+ + T+L+ ++P L P ++ TS DKP T P+ A
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 659 PKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFA-LVPLTESQGPPHSGS 717
PK P + E +S + P + ++ TPE A P P G
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 718 GSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPP 777
+ + + K + +D LR TP + K+T + +
Sbjct: 858 PTTKTPA---------ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT------ 902
Query: 778 GKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK-KRKGEAERDCDNKKIRLEKEIKSQ 836
+ ++ E K + +S + K+ K A + KK EI ++
Sbjct: 903 ---TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 959
Query: 837 SSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQK 876
++ ++ +K + P Q K P P S+ K
Sbjct: 960 PEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPK 997
Score = 71.6 bits (174), Expect = 4e-12
Identities = 106/545 (19%), Positives = 170/545 (31%), Gaps = 71/545 (13%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
PSP P P + ++ P T +K + K P K TP++
Sbjct: 473 PSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529
Query: 265 APAQPPSQTFPP---PSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKP------LPE 315
+ P+ T P P+ P + K A P + P E+ P PE
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 589
Query: 316 DYRQQTFEKTDLKVPAKAKLTKLKMPSQSV--EQTYSNEVHCVEEILKEMTHSWP----- 368
T EK P + T + P+ + E + KE + P
Sbjct: 590 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Query: 369 ----------PPLTAIHTPSTAEPS--KFPFPTKDSQ----HVSSVTQNQKQYDTSSKTH 412
P TA TP P+ K P PT + ++ T + T K
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709
Query: 413 SNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
+ +GT+ + + TP++P ++ +AP +L EP + A E
Sbjct: 710 PTTPKGTAPTTPKE---------PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 760
Query: 473 STSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
+ S + + + E T EP P T K + P PP
Sbjct: 761 LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-------PAPTTPETPPPTT 813
Query: 533 RSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-------PEAPHPGKRSC 585
P E S S +P PK+ +P+ P P A P +
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
Query: 586 QKSPAQQE----PPQRQTVGTKQPKKPVKASAR------AGSRTSLQGEREPGLLPYG-S 634
K + P+ T K K+ + + + T + P+ +
Sbjct: 874 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 933
Query: 635 RDQTSKDKPKVKT--KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN 692
+T+ PKV T K N+P+ P K++ P P K P+
Sbjct: 934 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 993
Query: 693 VEDRT 697
+ +T
Sbjct: 994 KKPKT 998
Score = 52.8 bits (125), Expect = 2e-06
Identities = 83/437 (18%), Positives = 148/437 (33%), Gaps = 55/437 (12%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAK-SPKDLAVKVHDKET----- 258
P+P P P + + T + P K +PK+LA + T
Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706
Query: 259 -PQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY 317
P + P + P P+ P + K TA + P + + P
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766
Query: 318 RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA-IHT 376
+ T +D P K T P + T E PPP T+ + T
Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPPTTSEVST 818
Query: 377 PSTA-EPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS 435
P+T EP+ +S S K + S K T + + ++ + + +
Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878
Query: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
P +++A P + + A+ + ES+ T+ + ++ +S+ +++
Sbjct: 879 TERDLRTTPETTTAAPK----MTKETATTTEKTTESKITATT-------TQVTSTTTQDT 927
Query: 496 EP-----LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P L+T P+ TT K +TE + E+ D
Sbjct: 928 TPFKITTLKTTTLAPKVTTTKKTIT------------------TTEIMNKPEETAKPKDR 969
Query: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
AT+ S++ P P+ +KAP+ P P + P P++ T T P
Sbjct: 970 ATN---SKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT-STMPELNPTS 1025
Query: 611 ASARAGSRTSLQGEREP 627
A A +T+ + + P
Sbjct: 1026 RIAEAMLQTTTRPNQTP 1042
Score = 50.4 bits (119), Expect = 1e-05
Identities = 85/486 (17%), Positives = 157/486 (32%), Gaps = 92/486 (18%)
Query: 492 SEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSA 551
+E + P P+ + PP + Q TK RS +PP + K
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTK-----------RSPKPPNKKKTKKVIESEE 112
Query: 552 TSQEHSESKDPPPKSSSKAP-------RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
++EHS S++ SSS + + R QK ++ + +T
Sbjct: 113 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 172
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
PK PV A +G + G + D ++ KV T + A P+P++P
Sbjct: 173 PKPPVVDEAGSGL--------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 224
Query: 665 PSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGC 724
P+S+ K S + E N + T +T+
Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTD------------------GKEKTTSA 266
Query: 725 RQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQR 784
++ +++ S KD P +K+L+ P P++ + KG
Sbjct: 267 KETQSIEKTSAKDLAPT----SKVLAK----PTPKA--------------ETTTKGPALT 304
Query: 785 KAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSH 844
++ P K+ +S + + + K + + +
Sbjct: 305 TPKEPTPTTPKEPASTTPKEPTPTTI--------------------KSAPTTPKEPAPTT 344
Query: 845 KESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTK 904
+S+ T P P+ ++K+ P ++ ++PA K PK + T
Sbjct: 345 TKSAPTTPKEPAPTTTKE------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398
Query: 905 SNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQA 964
+ PK+ + + K + T P P + P KP K+ A
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458
Query: 965 DLHMRE 970
+E
Sbjct: 459 PTTPKE 464
Score = 37.4 bits (85), Expect = 0.087
Identities = 57/302 (18%), Positives = 111/302 (36%), Gaps = 33/302 (10%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
P+P P P + +T P T +S+V + + KSP + ++ + TP+
Sbjct: 793 PAPTTPKKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850
Query: 265 APAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEK 324
+P +P T P+ + K R + + + +P++ ++T
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT-------KETATT 903
Query: 325 TDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSK 384
T+ +K T ++ S + + T ++ LK T + P T T +T E
Sbjct: 904 TEKTTESKITATTTQVTSTTTQDTTPFKI----TTLKTTTLA-PKVTTTKKTITTTEIMN 958
Query: 385 FPFPT---KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
P T KD S T + Q T + S + +M
Sbjct: 959 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM----------------PRV 1002
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
KP ++ P ++PE ++ + A ++T+ + + +S+ + SE+ E
Sbjct: 1003 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062
Query: 502 AP 503
P
Sbjct: 1063 TP 1064
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 89.4 bits (220), Expect = 2e-17
Identities = 159/801 (19%), Positives = 277/801 (34%), Gaps = 111/801 (13%)
Query: 216 SNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA--------VKVHDKETPQDSLVAPA 267
+ + ++ Q SS SS++S KS K+ A +KV D + +
Sbjct: 155 TEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 214
Query: 268 QPP--------------SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPL 313
+PP T P S + +P++ + P S K
Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 274
Query: 314 PEDYRQQTFEKT--------DLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTH 365
++T +T K K T K +QS+E+T + ++ ++L + T
Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPT- 332
Query: 366 SWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLED 425
P T P+ P K P PT + S+ + S + + ++
Sbjct: 333 --PKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 426 DLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSES 485
+ + +++ P AP + + P SA ++ E T+ + +
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 486 ESSSSDSEENEPLETPAPEP---EP-PTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRR 540
E + + +E P P P EP PTT K +PA P+ P T P
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-----------EPAPTAPKKPAPTTPKEP 498
Query: 541 HPESKGSSDSATSQEHSES--KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQ 598
P + T++E S + K+P P ++ AP E +S +P + P +
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558
Query: 599 TVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNE 658
PK+P + + + T+ +EP T+ +P T +P E
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTT---PKEPA--------PTTPKEPAPTTTKKPAPTTPKE 607
Query: 659 PKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSG 718
P P P + K P + L+ P K TPE A P T + P +
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP--APTTPEELA--PTTPEEPTPTTPEE 663
Query: 719 SRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPP-PQSLMVKITLDLLSRIPQPP 777
+ + A ++ K+ P ++ +P P P+ + P
Sbjct: 664 PAPTTPKAAA---PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 778 GKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIK--S 835
+ ++ A + P K E S+ KG A KE +
Sbjct: 721 APTTPKKPAPKELAPTTTK---EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 777
Query: 836 QSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP---PVSSSSQKPA-------------K 879
++ ++ KE + T P +P+ KE+ P P S++S KPA +
Sbjct: 778 PKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833
Query: 880 PALKRSRREADTCGQDPPKSAS--STKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTA 937
PA ++ A T + PP + S ST + K+ + + S + + +A
Sbjct: 834 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-----------TIHKSPDESTPELSA 882
Query: 938 NPFPVPSLPNGNSKPGKPQVK 958
P P +L N +PG P K
Sbjct: 883 EPTP-KALENSPKEPGVPTTK 902
Score = 75.1 bits (183), Expect = 4e-13
Identities = 178/880 (20%), Positives = 308/880 (35%), Gaps = 127/880 (14%)
Query: 81 DASENRLGK---PKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQ 137
D +NR K PK P++ + GS + + F + TP + +S +PK+
Sbjct: 202 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDF-------KVTTPDTSTTQHNKVSTSPKITT 254
Query: 138 PRT-EPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPE- 195
+ P PSL S D+ T + +E + + T SA E
Sbjct: 255 AKPINPRPSLPPNS----DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 310
Query: 196 --------RELSP---LISLPSPV-------PPLSPIHSNQQTLPRTQGSSKVHGSSNNS 237
++L+P +++ P+P P L+ T P+ S+ + +
Sbjct: 311 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370
Query: 238 KGYCPAKSPKDLAVKVHDKE--TPQDSLVAPAQPPSQTFPPPSLPSKS-----VAMQQKP 290
P +PK+ A TP++ + P+ T P P+ + + P
Sbjct: 371 IKSAPT-TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429
Query: 291 TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS 350
T P + P+ + +P P ++ T T K PA TK P+ E +
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPT--TKEPAPTTPKEPAPT 485
Query: 351 NEVHCVEEILKEMTHSWP--PPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTS 408
KE + P P T PS P K P PT + T + T+
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-KEPAPTTTKS--APTTTKEPAPTTT 542
Query: 409 SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVAS----- 463
+ ++ + + ++ + E + + TP+KP ++ AP + EP +
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPT--TPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Query: 464 AHSSSAESESTSDSDSSSDSESESSSSDSEENEPL--ETPAP------------EPEP-- 507
A ++ E T+ +++ + + + + E+ P E PAP EP P
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 508 -----PTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSES--K 560
PTT K N K P P E P T P P + + T + + + K
Sbjct: 661 PEEPAPTTPKAAAPN-TPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 718
Query: 561 DPPPKSSSK-APR--APPEAPHPGKRSCQK----SPAQQEPPQRQTVGTKQPKKPVKASA 613
+P P + K AP+ AP P +C K +P P + PK+P +
Sbjct: 719 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 778
Query: 614 RAGSRTSLQGE-----REPG---LLPYGSRDQTS--KDKPKVKTKGR-----PRAAASNE 658
+ + T+L+ ++P L P ++ TS DKP T P+ A
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 659 PKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFA-LVPLTESQGPPHSGS 717
PK P + E +S + P + ++ TPE A P P G
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 718 GSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPP 777
+ + + K + +D LR TP + K+T + +
Sbjct: 899 PTTKTPA---------ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT------ 943
Query: 778 GKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK-KRKGEAERDCDNKKIRLEKEIKSQ 836
+ ++ E K + +S + K+ K A + KK EI ++
Sbjct: 944 ---TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 1000
Query: 837 SSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQK 876
++ ++ +K + P Q K P P S+ K
Sbjct: 1001 PEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPK 1038
Score = 71.6 bits (174), Expect = 4e-12
Identities = 106/545 (19%), Positives = 170/545 (31%), Gaps = 71/545 (13%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
PSP P P + ++ P T +K + K P K TP++
Sbjct: 514 PSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570
Query: 265 APAQPPSQTFPP---PSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKP------LPE 315
+ P+ T P P+ P + K A P + P E+ P PE
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 630
Query: 316 DYRQQTFEKTDLKVPAKAKLTKLKMPSQSV--EQTYSNEVHCVEEILKEMTHSWP----- 368
T EK P + T + P+ + E + KE + P
Sbjct: 631 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Query: 369 ----------PPLTAIHTPSTAEPS--KFPFPTKDSQ----HVSSVTQNQKQYDTSSKTH 412
P TA TP P+ K P PT + ++ T + T K
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750
Query: 413 SNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
+ +GT+ + + TP++P ++ +AP +L EP + A E
Sbjct: 751 PTTPKGTAPTTPKE---------PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 801
Query: 473 STSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
+ S + + + E T EP P T K + P PP
Sbjct: 802 LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-------PAPTTPETPPPTT 854
Query: 533 RSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-------PEAPHPGKRSC 585
P E S S +P PK+ +P+ P P A P +
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
Query: 586 QKSPAQQE----PPQRQTVGTKQPKKPVKASAR------AGSRTSLQGEREPGLLPYG-S 634
K + P+ T K K+ + + + T + P+ +
Sbjct: 915 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 974
Query: 635 RDQTSKDKPKVKT--KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN 692
+T+ PKV T K N+P+ P K++ P P K P+
Sbjct: 975 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 1034
Query: 693 VEDRT 697
+ +T
Sbjct: 1035 KKPKT 1039
Score = 52.8 bits (125), Expect = 2e-06
Identities = 83/437 (18%), Positives = 148/437 (33%), Gaps = 55/437 (12%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAK-SPKDLAVKVHDKET----- 258
P+P P P + + T + P K +PK+LA + T
Sbjct: 688 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 747
Query: 259 -PQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY 317
P + P + P P+ P + K TA + P + + P
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807
Query: 318 RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTA-IHT 376
+ T +D P K T P + T E PPP T+ + T
Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--------PPPTTSEVST 859
Query: 377 PSTA-EPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS 435
P+T EP+ +S S K + S K T + + ++ + + +
Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919
Query: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
P +++A P + + A+ + ES+ T+ + ++ +S+ +++
Sbjct: 920 TERDLRTTPETTTAAPK----MTKETATTTEKTTESKITATT-------TQVTSTTTQDT 968
Query: 496 EP-----LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
P L+T P+ TT K +TE + E+ D
Sbjct: 969 TPFKITTLKTTTLAPKVTTTKKTIT------------------TTEIMNKPEETAKPKDR 1010
Query: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
AT+ S++ P P+ +KAP+ P P + P P++ T T P
Sbjct: 1011 ATN---SKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT-STMPELNPTS 1066
Query: 611 ASARAGSRTSLQGEREP 627
A A +T+ + + P
Sbjct: 1067 RIAEAMLQTTTRPNQTP 1083
Score = 50.4 bits (119), Expect = 1e-05
Identities = 85/486 (17%), Positives = 157/486 (32%), Gaps = 92/486 (18%)
Query: 492 SEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSA 551
+E + P P+ + PP + Q TK RS +PP + K
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTK-----------RSPKPPNKKKTKKVIESEE 153
Query: 552 TSQEHSESKDPPPKSSSKAP-------RAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
++EHS S++ SSS + + R QK ++ + +T
Sbjct: 154 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 213
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
PK PV A +G + G + D ++ KV T + A P+P++P
Sbjct: 214 PKPPVVDEAGSGL--------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 265
Query: 665 PSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGC 724
P+S+ K S + E N + T +T+
Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTD------------------GKEKTTSA 307
Query: 725 RQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQR 784
++ +++ S KD P +K+L+ P P++ + KG
Sbjct: 308 KETQSIEKTSAKDLAPT----SKVLAK----PTPKA--------------ETTTKGPALT 345
Query: 785 KAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSH 844
++ P K+ +S + + + K + + +
Sbjct: 346 TPKEPTPTTPKEPASTTPKEPTPTTI--------------------KSAPTTPKEPAPTT 385
Query: 845 KESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTK 904
+S+ T P P+ ++K+ P ++ ++PA K PK + T
Sbjct: 386 TKSAPTTPKEPAPTTTKE------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439
Query: 905 SNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQA 964
+ PK+ + + K + T P P + P KP K+ A
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499
Query: 965 DLHMRE 970
+E
Sbjct: 500 PTTPKE 505
Score = 37.4 bits (85), Expect = 0.087
Identities = 57/302 (18%), Positives = 111/302 (36%), Gaps = 33/302 (10%)
Query: 205 PSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLV 264
P+P P P + +T P T +S+V + + KSP + ++ + TP+
Sbjct: 834 PAPTTPKKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891
Query: 265 APAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEK 324
+P +P T P+ + K R + + + +P++ ++T
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT-------KETATT 944
Query: 325 TDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSK 384
T+ +K T ++ S + + T ++ LK T + P T T +T E
Sbjct: 945 TEKTTESKITATTTQVTSTTTQDTTPFKI----TTLKTTTLA-PKVTTTKKTITTTEIMN 999
Query: 385 FPFPT---KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441
P T KD S T + Q T + S + +M
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM----------------PRV 1043
Query: 442 EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETP 501
KP ++ P ++PE ++ + A ++T+ + + +S+ + SE+ E
Sbjct: 1044 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103
Query: 502 AP 503
P
Sbjct: 1104 TP 1105
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 79.7 bits (195), Expect = 2e-14
Identities = 113/553 (20%), Positives = 199/553 (35%), Gaps = 34/553 (6%)
Query: 389 TKDSQHVSSVTQNQKQYDTS-SKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSS 447
+ DS S + + D+S SK+ S+ + SS + SDS SDS + SS
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 448 SAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEP 507
++ S+ S +S SSS++S ++SDS SSDS + S SSDS ++ ++ + +
Sbjct: 661 NSSNSSDSS-DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS-SDSSDS 718
Query: 508 PTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSS 567
+N D+ + S ++ + +S SSDS+ S + S+S D SS
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD----SS 774
Query: 568 SKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREP 627
+ + + S S + + + + + S +S +
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 628 GLLPYGSRDQT-SKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGP 686
S D + S D + R ++ S++ + S+ SS S S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 687 EPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDT 746
+ ++ + + ++S S S +S ++ ++S D+
Sbjct: 895 SDSSNSSDSDS---------SDSSNSSDSSDSSNSSDSSESSNSSDNSNSS-------DS 938
Query: 747 KLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKR-SSD 805
S D+ + + D + S + D + SS+ SSD
Sbjct: 939 SNSSDSSDSSDSSN-----SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993
Query: 806 SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEML 865
SS ++ D+ + S +SS SS+ +SS + S SS SS
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSD--SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 866 PPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRS 925
SS S + + ++ S SS SN DSS S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS--SDSSDSS 1109
Query: 926 SSEHKGSSGDTAN 938
S S D++N
Sbjct: 1110 DSSDSSDSSDSSN 1122
Score = 79.3 bits (194), Expect = 2e-14
Identities = 106/545 (19%), Positives = 182/545 (33%), Gaps = 23/545 (4%)
Query: 396 SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQ 455
SS + N SS + S+ +S D SDS DSDS + SS + S+
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 456 SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQL 515
S S+ SS ++S+S+ SSDS+S+S SSDS ++ + ++N
Sbjct: 614 S-----DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN---- 664
Query: 516 DNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPP 575
+ S ++ S+ +S SSDS+ S E S+S D SS
Sbjct: 665 ----SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS------- 713
Query: 576 EAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSR 635
++ + S + + + +S + S S
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 636 DQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVED 695
+S + ++ S++ + S+ SS + S + + + + +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 696 RTPEHFALVPLTESQGPPHSGSGSRTSGCRQA-VVVQEDSRKDRLPLPLRDTKLLSPLRD 754
+ ++S S S +R+ + DS D+ S D
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 755 TPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKR 814
+ + + D S + +E S SSDSS
Sbjct: 894 SSDSSNSSDSDSSD-SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 815 KGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSS 874
++ D+ + S SS SS+ +SS + S SS SS SS S
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 875 QKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSS-SEHKGSS 933
+ + + ++ S SS S+ DSS S SS S S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Query: 934 GDTAN 938
D+++
Sbjct: 1073 SDSSD 1077
Score = 75.5 bits (184), Expect = 3e-13
Identities = 105/533 (19%), Positives = 179/533 (33%), Gaps = 11/533 (2%)
Query: 408 SSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSS 467
S K S+S SS + SDS DSDS + S S+ + S + + +S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 468 SAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAA 527
S S+S+ SDSS S+S S SDS ++E ++ + + +++ D+ S ++
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSES-DSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 528 PPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQK 587
+ +S SSDS+ S + S+S D S S ++
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 588 SPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647
S + + + + + S +S + S D + +
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 648 KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
+SN + S+ SS + S S + + + + + +
Sbjct: 781 NSSDSNDSSNS-SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL 767
+S S GS + ++ DS D+ S D+ S +
Sbjct: 840 DSSDSSDSSDGSDSDSSNRS-----DSSNSSDSSDSSDSSNSSDSSDS--SDSNESSNSS 892
Query: 768 DLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE-KRSSDSSSKLAKKRKGEAERDCDNKK 826
D S + D + SSE SSD+S+ ++ D+
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 827 IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSR 886
S+SS SS SS + S SS SS SS S + +
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 887 READTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSS-SEHKGSSGDTAN 938
++ S SS S+ DSS S SS S + S D+++
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Score = 73.2 bits (178), Expect = 1e-12
Identities = 108/549 (19%), Positives = 179/549 (32%), Gaps = 53/549 (9%)
Query: 396 SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSA-- 453
SS + + SS + +S SS D SDS DSDS + + SS + S+
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 454 ---PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTT 510
S S SS S+S++ SDSS S+S +SS S+ ++ E+ ++
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 511 NKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKS-SSK 569
N D+ + S ++ + ++ SSDS+ S + S+S D S SS
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 570 APRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGL 629
+ + + S S + + + +S + S S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 630 LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPA 689
+ +S + ++ S++ + S+ SS + S S +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 690 KDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL 749
D+ E ++S +S S +S + DS D+
Sbjct: 1079 SDSSES-----------SDSSDSSNSSDSSDSSDSSDS----SDSSDSSDSSDSSDSSNS 1123
Query: 750 SPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809
S D+ S + D + SSE S SS
Sbjct: 1124 SDSSDS-------------------------SDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158
Query: 810 LAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
+ D + S +SS SS +SS + S SS SS
Sbjct: 1159 SSDSSDSSDSSDSSDSS-------DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
SS S + + +++ S SS SN DSS S S+
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDS 1271
Query: 930 KGSSGDTAN 938
+ SG+ N
Sbjct: 1272 QSKSGNGNN 1280
Score = 72.4 bits (176), Expect = 2e-12
Identities = 108/579 (18%), Positives = 191/579 (32%), Gaps = 31/579 (5%)
Query: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
S +E +K S+ + + D+S ++S++ +S + S S+ S+S
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 438 EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEP 497
+ + SS++ S+ S S+ SS + + ++SDSDSS+ S+S SS+ S+ ++
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 498 LE----TPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATS 553
+ + + + + + D+ + S ++ + +S SSDS+ S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 554 QEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASA 613
+ S+S D SS + + + + S + + +S
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 614 RAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHK 673
+ S S S D + + + +SN SS
Sbjct: 867 SSDSSDS-----------SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 674 SSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQED 733
S + + S N D + + S S S ++ + D
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 734 SRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPA 793
S D+ S D+ + S S + D +
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSN----------SSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 794 GKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQS--SSSSSSHKESSKTK 851
+SS+ S SS + D N + S S SS SS +SS++
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 852 PSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSS 911
S SS SS SS S + + + S SS SN DSS
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 912 IPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNS 950
E S SS+ SS + + S + NS
Sbjct: 1146 DSS----ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Score = 72.4 bits (176), Expect = 2e-12
Identities = 109/578 (18%), Positives = 186/578 (32%), Gaps = 31/578 (5%)
Query: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
S++ S + DS S+ +++ D+S S+S ++S D + S+ SDS
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 438 EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDS-----------SSDSESE 486
+ + SS + S+ S +++ SS S+S+ SDS SSDS
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 487 SSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKG 546
S+SSDS + + + ++N N + S +S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Query: 547 SSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPK 606
SDS+ S + S+S D SS+ + + + S S + + +
Sbjct: 858 RSDSSNSSDSSDSSD----SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 607 KPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPS 666
+++ S +S + S D + + + +SN + S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 667 SEKK-KHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCR 725
S+ SS + S S + D+ + + + + S S S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 726 QAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRK 785
DS D+ S D+ S S +
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD----------SSDSSDSSDSSDSSE 1083
Query: 786 AEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSS-- 843
+ D + SS+ S SS + D N + S SS SS+S
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 844 ---HKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
ESS + S SS SS SS S + + ++ S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTAN 938
SS S+ DSS S SS ++ S ++
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Score = 67.4 bits (163), Expect = 8e-11
Identities = 110/565 (19%), Positives = 185/565 (32%), Gaps = 25/565 (4%)
Query: 391 DSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP 450
D +S T N + + ++ + S + D SDS DS + S +
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 451 PSAPQSLPEPVASAHSSSAESESTSDSDS--SSDSESESSSSDSEENEPLETPAPEPEPP 508
S S + S S S++S+S+ S+S SSDS S SSDS ++ ++ + + E
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 509 TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSS 568
+++ + S ++ + +S SSDS+ S S+S + S S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 569 KAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPG 628
E+ S S + + + + + S +S +
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 629 LLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEP 688
S D ++ + + +SN + S+ SS + S S
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 689 AKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKL 748
+ D+ + + ++S +S S +S +R D ++
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS-----SNSSD 866
Query: 749 LSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSS 808
S D+ S + S + D + S SSDSS
Sbjct: 867 SSDSSDSSNSSD----------SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 809 KLAKKRKGEAERDCDNKKIR-LEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPP 867
E+ DN S SS SS+ +SS + S SS SS
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976
Query: 868 PPVSSSSQKPAKPALKRSRREADT--CGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRS 925
S+SS S +D+ S SS SN DSS + S
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS----NSSDSSNSSD 1032
Query: 926 SSEHKGSSGDTANPFPVPSLPNGNS 950
SS+ SS + + S + NS
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNS 1057
Score = 61.2 bits (147), Expect = 6e-09
Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 4/194 (2%)
Query: 375 HTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSED 434
++ ++E S + S +S + ++S SNS ++S D SDS D
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Query: 435 SDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEE 494
S + SS + S +S S S++S ++SDS +SSDS + S SSDS +
Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Query: 495 NEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQ 554
+ + + ++ + + S + + S++ ES SSDS+ S
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD----SSESSDSSDSSNSS 1094
Query: 555 EHSESKDPPPKSSS 568
+ S+S D S S
Sbjct: 1095 DSSDSSDSSDSSDS 1108
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 14/179 (7%)
Query: 389 TKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSS 448
+ DS S + + D+S ++S+ +S + + S+ SDS ++ + SS
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158
Query: 449 APPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPP 508
+ S+ S + + SS S+S+ SDSS S+S SS S+ ++ ++
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS------- 1211
Query: 509 TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSS 567
D+ + S ++ + +S SSDS+ S + S+S D +S
Sbjct: 1212 -------DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Score = 54.3 bits (129), Expect = 7e-07
Identities = 38/173 (21%), Positives = 69/173 (39%), Gaps = 5/173 (2%)
Query: 389 TKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSS 448
+ DS S + + D+S + S+ +S + S+ SDS + SS
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 449 APPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPP 508
+ S+ S + + SS S+S+ SDSS S+S SS S+ NE ++
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Query: 509 TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561
++N + S ++ + E + G+++ + S SE D
Sbjct: 1246 SSNSSDSSD-----SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Score = 54.3 bits (129), Expect = 7e-07
Identities = 43/164 (26%), Positives = 64/164 (39%), Gaps = 4/164 (2%)
Query: 396 SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQ 455
SS + N SS++ +S SS D SDS DS SS +
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 456 SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQL 515
S +S S S++S +SDS SSDS S SSDS E+ + + ++
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS---- 1250
Query: 516 DNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSES 559
D+ + S + S + + SDS + E S+S
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDS 1294
Score = 53.9 bits (128), Expect = 9e-07
Identities = 42/180 (23%), Positives = 71/180 (39%), Gaps = 14/180 (7%)
Query: 389 TKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSS 448
+ DS S + + D+S + S++ +S + S SDS + E SS
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Query: 449 APPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPP 508
+ S+ S + + SS S S+ SDSS S+S SS S+ ++ ++
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS------- 1208
Query: 509 TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSS 568
D+ + S ++ + +S SSDS+ S S+S D S S
Sbjct: 1209 -------DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261
Score = 48.9 bits (115), Expect = 3e-05
Identities = 30/119 (25%), Positives = 53/119 (44%)
Query: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
S + S + DS S + + D+S + S+ +S + S+ SDS
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 438 EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE 496
+ + SS + S+ S + + SS +ES+ SDSS S+S +SS S+ ++
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257
Score = 44.7 bits (104), Expect = 5e-04
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 15/122 (12%)
Query: 389 TKDSQHVSSVTQNQKQYDTSSKTHSN--SQQGTSSMLEDDLQLSDSEDS-DSEQTPEKPP 445
+ DS + S + + D+S + S+ S SS D SDS DS DS + +
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 446 SSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSES------------ESSSSDSE 493
SS + S+ S + + SS S+STSDS+ SDS+S +S S S+
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Query: 494 EN 495
N
Sbjct: 1294 SN 1295
Score = 35.0 bits (79), Expect = 0.43
Identities = 37/170 (21%), Positives = 58/170 (34%), Gaps = 19/170 (11%)
Query: 778 GKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK---------LAKKRKGEAERDCDNKKIR 828
G GS + AED + +S+ +SDS+ + KG+++ +
Sbjct: 502 GNGSDSKGAEDDDSDS----TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 829 LEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRRE 888
S SS S SS SS S S S + SS + + S
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS------DSSDSSNSSDSSDSSDSS 611
Query: 889 ADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTAN 938
+ D S S + + DSS + + S S S D++N
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 77.0 bits (188), Expect = 1e-13
Identities = 185/856 (21%), Positives = 302/856 (35%), Gaps = 141/856 (16%)
Query: 204 LPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYC------------PAKSPKDLAV 251
+P PVP L P L + V SN+S+ C PA P +
Sbjct: 140 IPLPVPSLLP------RLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSA 193
Query: 252 KVHDKETPQDSLVAPAQPPSQTFPP-PSLPSKSVAMQQKPT--AY---------VRPMDG 299
+P S +P PP PP P P + PT AY P +
Sbjct: 194 SSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEP 253
Query: 300 QDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEI 359
PS S P PE+ ++ E+ + + + E+ S + + E
Sbjct: 254 TGSNPSSSAGT-PSPEEEEEEEEEEEE------------EEEDEEEEEGLSQSISRISET 300
Query: 360 L------KEMTHSWPPPLTAIHTPSTAEPSKFPF--PTKDSQHVSSVTQNQKQYDTSSKT 411
L ++ +P + +P+ P P DS + ++ + ++
Sbjct: 301 LAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMR-RRVFVVGTEA 359
Query: 412 HSNSQ---------QGTSSMLEDDLQLSDSEDSDSEQT-PEKPPS---SSAPPSAPQSLP 458
+ + G +++ L DSE + E PE+ P S P + P
Sbjct: 360 EACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARP 419
Query: 459 EPVASAHSSSAE--SESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN-KW-- 513
P ASA ++ + D S + SD E ++ P P PP + +W
Sbjct: 420 TPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGG 479
Query: 514 ----------QLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPP 563
+ + + + PA P + PP R + S ++E + S
Sbjct: 480 LDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASS---- 535
Query: 564 PKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQG 623
SS APP P +K ++ P + + + ++ +R+ R S
Sbjct: 536 ---SSGTQPAPPAPASPW--DSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRST 590
Query: 624 EREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKAL 683
+R G GSR S++K + R R +AS P + SS +++H+ +
Sbjct: 591 DRRRG----GSRRSRSREKRR-----RRRRSASPPPATSSSSSSRRERHRGKHRDGGGSK 641
Query: 684 SGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGS---GSRTSGCRQAVVVQEDSRKDRLP 740
+ ++ E R+ + P + PP SGS G R S R AV D
Sbjct: 642 KKKKRSRSRGEKRSGDGSEKAP---APAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDL 698
Query: 741 LPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE 800
++ T + L + P + + G +R + Q ++ S
Sbjct: 699 FAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKD--RRRSGA 756
Query: 801 KRSSDSSSKLAKKRK----GEAERDCD--------NKKIRLEKEIKSQSS-------SSS 841
SS SS + +RK G+ +RD D +KK R KE S SS
Sbjct: 757 ASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSG 816
Query: 842 SSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPA---------LKRSR-READT 891
S SS + SR SK +L VSS++ PAK A +K SR RE+ +
Sbjct: 817 SGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTT--PAKDAASAGLGSIGVKFSRDRESRS 874
Query: 892 CGQDPPKSASSTKSNHKDSSI-PKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNS 950
P + A + + S PK+ +V+ K + + KG+ G T + +G
Sbjct: 875 PFLKPDERAPTEMAKAAPGSTKPKKTKVKAKA--GAKKTKGTKGKTKPSKTRKKVRSGGG 932
Query: 951 KPGK-PQVKFDKQQAD 965
G QV K +AD
Sbjct: 933 SGGSGGQVSLKKSKAD 948
Score = 57.8 bits (138), Expect = 6e-08
Identities = 125/556 (22%), Positives = 188/556 (33%), Gaps = 121/556 (21%)
Query: 501 PAPEPEP---PTTNKWQLDNWLTKVSQPAAPP--------EGPRSTEPPRRHPESKGSSD 549
P P P P P W+ ++ S + P G PP P +S
Sbjct: 139 PIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPP---PAPSSASS 195
Query: 550 SATSQEHSESKDPPPKSSSKAPRAPPEAP--------HPGKRSCQKSPAQQ------EPP 595
S + S S PPP AP APP AP HP + PA + EP
Sbjct: 196 SPSPSPSSSSPSPPPPPPPPAPPAPP-APRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPT 254
Query: 596 ---QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSR-----------DQTSKD 641
+ GT P++ + E E GL SR + S+D
Sbjct: 255 GSNPSSSAGTPSPEEEEEEEEEEEEEEE-DEEEEEGLSQSISRISETLAGIYDDNSLSQD 313
Query: 642 KPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPA----KDNVEDRT 697
P ++ P P PP + + ++ + A K +VE T
Sbjct: 314 FPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVT 373
Query: 698 PEHFALVPLTESQGPPHSGSG---SRTSGCRQAVVVQEDSRKDRLPLPLRD-TKLLSPLR 753
AL P G G R A+ + + P P T PL
Sbjct: 374 AGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLP 433
Query: 754 DTPPPQ--------SLMVK------ITLDLLSRIPQPPGKGSR------------QRKAE 787
P P+ SL + + +DL P PP SR QR+
Sbjct: 434 QPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRER 493
Query: 788 DKQ----------------PPAGKKHSSEKRSSDSSSKLAKKRKG------EAERDCDNK 825
+Q PP KK E++ S + + A G D+K
Sbjct: 494 YRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSK 553
Query: 826 KIRLEKEIKSQSSSSSSSHKES---SKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPAL 882
K R ++ K S +SSS+ + S S+++ +R S+S+ + S + ++
Sbjct: 554 KHR-SRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRR------GGSRRSRSREKR 606
Query: 883 KRSRREADTCGQDPPKSASSTKSNHKDSSIPKQR-----RVEGKGSRSSSEHKGSSGDTA 937
+R RR A PP + SS+ S+ ++ K R + + K SRS E + G
Sbjct: 607 RRRRRSA-----SPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEK 661
Query: 938 NPFPVPSLPNGNSKPG 953
P P P P+G++ G
Sbjct: 662 APAPAPP-PSGSTSCG 676
Score = 49.7 bits (117), Expect = 2e-05
Identities = 69/307 (22%), Positives = 108/307 (35%), Gaps = 53/307 (17%)
Query: 397 SVTQNQKQYDTSSKTHSNSQQGTSSMLED----DLQLSDSEDSDSEQTPEKPPSSSAPPS 452
S +++++ +S + S+ ++G+ D D D D +PP SAP S
Sbjct: 746 SSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSS 805
Query: 453 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK 512
P P PV+S SS+ S S S + K
Sbjct: 806 GPPPKP-PVSSGSGSSSSSSSCS----------------------------------SRK 830
Query: 513 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR 572
+L + + + + EG ST P + + S ES+ P K +AP
Sbjct: 831 VKLQSKVAVLIR-----EGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPT 885
Query: 573 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY 632
+A PG +K+ + + ++T GTK KP K + S G L
Sbjct: 886 EMAKAA-PGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKK 944
Query: 633 GSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN 692
D S+ TKG + S E + A PS+ K AP P+ +
Sbjct: 945 SKADSCSQ---AAGTKGAEETSWSGEERAAKVPSTPPPK-----AAPPPPALTPDSQTVD 996
Query: 693 VEDRTPE 699
+TPE
Sbjct: 997 SSCKTPE 1003
Score = 46.2 bits (108), Expect = 2e-04
Identities = 85/347 (24%), Positives = 130/347 (37%), Gaps = 57/347 (16%)
Query: 163 RLGQEGFGSSHHKKGDRRA--DGDHCASVTDSAPERELS------PLISLPSPVPPLSPI 214
R G SS +KG RR DG D +R+ S P S PS PP P
Sbjct: 753 RSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKP- 811
Query: 215 HSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTF 274
P + GS GSS++S K V V +E S PA+ +
Sbjct: 812 -------PVSSGS----GSSSSSSSCSSRKVKLQSKVAVLIREGV--SSTTPAKDAASA- 857
Query: 275 PPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAK 334
S+ K ++ + +++P ++AP+E + P +KT +K A AK
Sbjct: 858 GLGSIGVKFSRDRESRSPFLKP---DERAPTEMAKAAP-----GSTKPKKTKVKAKAGAK 909
Query: 335 LTK----LKMPSQSVEQTYSN--------EVHCVEEILKEMTH----------SWPPPLT 372
TK PS++ ++ S +V + + SW
Sbjct: 910 KTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEER 969
Query: 373 AIHTPSTAEPSKFPFP---TKDSQHV-SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ 428
A PST P P P T DSQ V SS + + T +G + E++ +
Sbjct: 970 AAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEE 1029
Query: 429 LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTS 475
+ E+ + EQ P ++S +AP + P ++A S AE S
Sbjct: 1030 EEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAS 1076
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 76.6 bits (187), Expect = 1e-13
Identities = 133/635 (20%), Positives = 218/635 (34%), Gaps = 115/635 (18%)
Query: 390 KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA 449
++S +S + N + +T K+ ++ SS L+ + + + SD+E+ SS
Sbjct: 57 RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKK 114
Query: 450 PPSAPQSLPEPVASAHSSSAESESTSDSDSS-----------------SDSESESSSSDS 492
+ S P + S++S S +D SS S ++ES S S
Sbjct: 115 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174
Query: 493 EENEPLE------------TPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG-PRSTEPPR 539
+ + L+ TPAP PP T QL S A PP+G P +++ P
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTASQAPN 232
Query: 540 RH-------PESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-------PEAPH------ 579
+ P + A + S PPP S P P P AP
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292
Query: 580 -----PGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
PG S Q P Q P Q G P +AS QG+ G P +
Sbjct: 293 HGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQAS---------QGQAPLGTSPAAA 338
Query: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKA----------LS 684
TS P ++ + + +P P P + K + P P LS
Sbjct: 339 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398
Query: 685 GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLR 744
GP P N P AL PL+ H + + Q P L
Sbjct: 399 GPSPFSMNANLPPPP--ALKPLSSLS--THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 454
Query: 745 DTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG---SRQRKAEDKQPPAGKKHSSEK 801
++ L P + PP L ++ P PG + PPAG S++
Sbjct: 455 QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
Query: 802 RSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS--------SHKESSKTKPS 853
S +++ G + C +++++E + S S + + PS
Sbjct: 515 PCSGAAASGGSIAGGSS---CPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571
Query: 854 RPSSQS-------------SKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
S + ++ ++ P S K + A+++++REA+ ++ +
Sbjct: 572 HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-RER 630
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGD 935
K ++ ++R E SSS H+G D
Sbjct: 631 EKEKEKEREREREREREAERAAKASSSAHEGRLSD 665
Score = 45.4 bits (106), Expect = 3e-04
Identities = 101/485 (20%), Positives = 161/485 (33%), Gaps = 84/485 (17%)
Query: 205 PSPVPPLSPI--HSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDS 262
PSP PPL P+ + Q + P + +HG P + PQ
Sbjct: 266 PSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPF 318
Query: 263 LVAP----AQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYR 318
+ P Q P T P + P S+ + +A Q Q P L P P
Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL------QSQQPPREQPLPPAP---- 368
Query: 319 QQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPP-------- 370
+K P + +L P Q + + H M + PPP
Sbjct: 369 ---LAMPHIKPPPTTPIPQLPAP-----QAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
Query: 371 LTAIHTPSTAEP------SKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLE 424
L+ H PS P P P+ +Q +TQ+Q +H + +
Sbjct: 421 LSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-PGLTQSQN-LPPPPASHPPTGLHQVAPQP 478
Query: 425 DDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSE 484
Q TP PS+S PP+ P + +P S ++S S + S +
Sbjct: 479 PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 538
Query: 485 SESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPES 544
+ + D E EP E+P P P P+ T V P+ + R + R S
Sbjct: 539 IKEEALDDAE-EP-ESPPPPPRSPSPEP-------TVVDTPSHASQSARFYKHLDRGYNS 589
Query: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
+D P + SK + EA KR ++ ++ +++ ++
Sbjct: 590 CARTDLYFM----------PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERE 639
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP--- 661
++ + A ++ S S + P++ G R S EP P
Sbjct: 640 REREREREAERAAKAS------------SSAHEGRLSDPQLSGPGHMR--PSFEPPPTTI 685
Query: 662 -AVPP 665
AVPP
Sbjct: 686 AAVPP 690
Score = 33.5 bits (75), Expect = 1.3
Identities = 44/180 (24%), Positives = 62/180 (34%), Gaps = 28/180 (15%)
Query: 119 PASGPLSVGNISHNPK------MAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSS 172
PA PLS + H P P+++P+PS A+ G SQ+L +S
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-------PAS 465
Query: 173 HHKKGDRRADGDHCASVTDSAPERELSPLISLPSPV-PPLSPIHSNQQTLPRTQGSSKVH 231
H G V P + + P P+ PP P S P T
Sbjct: 466 HPPTG--------LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 517
Query: 232 GSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT 291
G++ + S V++ KE D P PP PPP PS + P+
Sbjct: 518 GAAASGGSIAGGSSCPLPTVQI--KEEALDDAEEPESPP----PPPRSPSPEPTVVDTPS 571
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 76.6 bits (187), Expect = 1e-13
Identities = 133/635 (20%), Positives = 218/635 (34%), Gaps = 115/635 (18%)
Query: 390 KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA 449
++S +S + N + +T K+ ++ SS L+ + + + SD+E+ SS
Sbjct: 611 RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKK 668
Query: 450 PPSAPQSLPEPVASAHSSSAESESTSDSDSS-----------------SDSESESSSSDS 492
+ S P + S++S S +D SS S ++ES S S
Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 493 EENEPLE------------TPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG-PRSTEPPR 539
+ + L+ TPAP PP T QL S A PP+G P +++ P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTASQAPN 786
Query: 540 RH-------PESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-------PEAPH------ 579
+ P + A + S PPP S P P P AP
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Query: 580 -----PGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
PG S Q P Q P Q G P +AS QG+ G P +
Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQAS---------QGQAPLGTSPAAA 892
Query: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKA----------LS 684
TS P ++ + + +P P P + K + P P LS
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 685 GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLR 744
GP P N P AL PL+ H + + Q P L
Sbjct: 953 GPSPFSMNANLPPPP--ALKPLSSLS--THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 1008
Query: 745 DTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG---SRQRKAEDKQPPAGKKHSSEK 801
++ L P + PP L ++ P PG + PPAG S++
Sbjct: 1009 QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Query: 802 RSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS--------SHKESSKTKPS 853
S +++ G + C +++++E + S S + + PS
Sbjct: 1069 PCSGAAASGGSIAGGSS---CPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
Query: 854 RPSSQS-------------SKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
S + ++ ++ P S K + A+++++REA+ ++ +
Sbjct: 1126 HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-RER 1184
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGD 935
K ++ ++R E SSS H+G D
Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSD 1219
Score = 45.4 bits (106), Expect = 3e-04
Identities = 101/485 (20%), Positives = 161/485 (33%), Gaps = 84/485 (17%)
Query: 205 PSPVPPLSPI--HSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDS 262
PSP PPL P+ + Q + P + +HG P + PQ
Sbjct: 820 PSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPF 872
Query: 263 LVAP----AQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYR 318
+ P Q P T P + P S+ + +A Q Q P L P P
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL------QSQQPPREQPLPPAP---- 922
Query: 319 QQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPP-------- 370
+K P + +L P Q + + H M + PPP
Sbjct: 923 ---LAMPHIKPPPTTPIPQLPAP-----QAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974
Query: 371 LTAIHTPSTAEP------SKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLE 424
L+ H PS P P P+ +Q +TQ+Q +H + +
Sbjct: 975 LSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-PGLTQSQN-LPPPPASHPPTGLHQVAPQP 1032
Query: 425 DDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSE 484
Q TP PS+S PP+ P + +P S ++S S + S +
Sbjct: 1033 PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 1092
Query: 485 SESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPES 544
+ + D E EP E+P P P P+ T V P+ + R + R S
Sbjct: 1093 IKEEALDDAE-EP-ESPPPPPRSPSPEP-------TVVDTPSHASQSARFYKHLDRGYNS 1143
Query: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
+D P + SK + EA KR ++ ++ +++ ++
Sbjct: 1144 CARTDLYFM----------PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERE 1193
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP--- 661
++ + A ++ S S + P++ G R S EP P
Sbjct: 1194 REREREREAERAAKAS------------SSAHEGRLSDPQLSGPGHMR--PSFEPPPTTI 1239
Query: 662 -AVPP 665
AVPP
Sbjct: 1240 AAVPP 1244
Score = 33.5 bits (75), Expect = 1.3
Identities = 44/180 (24%), Positives = 62/180 (34%), Gaps = 28/180 (15%)
Query: 119 PASGPLSVGNISHNPK------MAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSS 172
PA PLS + H P P+++P+PS A+ G SQ+L +S
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-------PAS 1019
Query: 173 HHKKGDRRADGDHCASVTDSAPERELSPLISLPSPV-PPLSPIHSNQQTLPRTQGSSKVH 231
H G V P + + P P+ PP P S P T
Sbjct: 1020 HPPTG--------LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 1071
Query: 232 GSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT 291
G++ + S V++ KE D P PP PPP PS + P+
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQI--KEEALDDAEEPESPP----PPPRSPSPEPTVVDTPS 1125
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 76.6 bits (187), Expect = 1e-13
Identities = 133/635 (20%), Positives = 218/635 (34%), Gaps = 115/635 (18%)
Query: 390 KDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA 449
++S +S + N + +T K+ ++ SS L+ + + + SD+E+ SS
Sbjct: 611 RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKK 668
Query: 450 PPSAPQSLPEPVASAHSSSAESESTSDSDSS-----------------SDSESESSSSDS 492
+ S P + S++S S +D SS S ++ES S S
Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 493 EENEPLE------------TPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG-PRSTEPPR 539
+ + L+ TPAP PP T QL S A PP+G P +++ P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTASQAPN 786
Query: 540 RH-------PESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-------PEAPH------ 579
+ P + A + S PPP S P P P AP
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Query: 580 -----PGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
PG S Q P Q P Q G P +AS QG+ G P +
Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQAS---------QGQAPLGTSPAAA 892
Query: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKA----------LS 684
TS P ++ + + +P P P + K + P P LS
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 685 GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLR 744
GP P N P AL PL+ H + + Q P L
Sbjct: 953 GPSPFSMNANLPPPP--ALKPLSSLS--THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT 1008
Query: 745 DTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG---SRQRKAEDKQPPAGKKHSSEK 801
++ L P + PP L ++ P PG + PPAG S++
Sbjct: 1009 QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Query: 802 RSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS--------SHKESSKTKPS 853
S +++ G + C +++++E + S S + + PS
Sbjct: 1069 PCSGAAASGGSIAGGSS---CPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
Query: 854 RPSSQS-------------SKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
S + ++ ++ P S K + A+++++REA+ ++ +
Sbjct: 1126 HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-RER 1184
Query: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGD 935
K ++ ++R E SSS H+G D
Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSD 1219
Score = 45.4 bits (106), Expect = 3e-04
Identities = 101/485 (20%), Positives = 161/485 (33%), Gaps = 84/485 (17%)
Query: 205 PSPVPPLSPI--HSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDS 262
PSP PPL P+ + Q + P + +HG P + PQ
Sbjct: 820 PSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGP------PGPHSLQAGPLLQHPGPPQPF 872
Query: 263 LVAP----AQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYR 318
+ P Q P T P + P S+ + +A Q Q P L P P
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL------QSQQPPREQPLPPAP---- 922
Query: 319 QQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPP-------- 370
+K P + +L P Q + + H M + PPP
Sbjct: 923 ---LAMPHIKPPPTTPIPQLPAP-----QAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974
Query: 371 LTAIHTPSTAEP------SKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLE 424
L+ H PS P P P+ +Q +TQ+Q +H + +
Sbjct: 975 LSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-PGLTQSQN-LPPPPASHPPTGLHQVAPQP 1032
Query: 425 DDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSE 484
Q TP PS+S PP+ P + +P S ++S S + S +
Sbjct: 1033 PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 1092
Query: 485 SESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPES 544
+ + D E EP E+P P P P+ T V P+ + R + R S
Sbjct: 1093 IKEEALDDAE-EP-ESPPPPPRSPSPEP-------TVVDTPSHASQSARFYKHLDRGYNS 1143
Query: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
+D P + SK + EA KR ++ ++ +++ ++
Sbjct: 1144 CARTDLYFM----------PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERE 1193
Query: 605 PKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP--- 661
++ + A ++ S S + P++ G R S EP P
Sbjct: 1194 REREREREAERAAKAS------------SSAHEGRLSDPQLSGPGHMR--PSFEPPPTTI 1239
Query: 662 -AVPP 665
AVPP
Sbjct: 1240 AAVPP 1244
Score = 33.5 bits (75), Expect = 1.3
Identities = 44/180 (24%), Positives = 62/180 (34%), Gaps = 28/180 (15%)
Query: 119 PASGPLSVGNISHNPK------MAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSS 172
PA PLS + H P P+++P+PS A+ G SQ+L +S
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-------PAS 1019
Query: 173 HHKKGDRRADGDHCASVTDSAPERELSPLISLPSPV-PPLSPIHSNQQTLPRTQGSSKVH 231
H G V P + + P P+ PP P S P T
Sbjct: 1020 HPPTG--------LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS 1071
Query: 232 GSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT 291
G++ + S V++ KE D P PP PPP PS + P+
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQI--KEEALDDAEEPESPP----PPPRSPSPEPTVVDTPS 1125
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 75.9 bits (185), Expect = 2e-13
Identities = 210/1156 (18%), Positives = 400/1156 (34%), Gaps = 146/1156 (12%)
Query: 72 STKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISH 131
ST+ H + + R KP DK P+ + T H S + P S N S+
Sbjct: 139 STEIHEQKRHCNTTRHSKPT-----DK----PTGNSKTIDHKSSTDNHEAPPTSEENSSN 189
Query: 132 NPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTD 191
K R + +S P DS ++ G++ + K + R ++VT
Sbjct: 190 QGKDPMIRNQ-------RSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTR 242
Query: 192 SAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNN--SKGYCPAKSPKDL 249
+ ++ PL S + S T G+S+ S + K +K+
Sbjct: 243 KS-DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKT 301
Query: 250 AVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPE 309
+ E +DS A T ++ ++++ + + P + + +E+
Sbjct: 302 TGTPEESEKTEDSRTTVASDKLLTKTTKNI-QETISANELTQSLAEPTEHGGRTANENNT 360
Query: 310 LKPL-PEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWP 368
P P + R++T + PA+ + + +++ + E E T +P
Sbjct: 361 PSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFP 420
Query: 369 PPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQ 428
T H TA + P P + ++H
Sbjct: 421 AEPTE-HGERTANENTTPSPAEPTEH---------------------------------- 445
Query: 429 LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESS 488
E + +E T PS + P + P SSSAES + ++ + S
Sbjct: 446 ---GERTANENTT---PSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPS 499
Query: 489 SSDSEENEPL---ETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESK 545
++ EN E P P PT N+ N T +S P P E +T + P
Sbjct: 500 PAEPTENRERTANENTTPSPAGPTENRETTANEKTTLS-PVEPTENRETTANEKTTPSPA 558
Query: 546 GSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQP 605
+++ + K SSS P E + SPA+ + +T K
Sbjct: 559 EPTENGQRTPFANEK---TTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTT 615
Query: 606 KKPVKASARAGSRTSLQGER-EPGL---------LPYGSRDQTSKD-KPKVKTKGRPRAA 654
P + + G RT L E+ P L P+ + TS +P + P A
Sbjct: 616 PSPAEPTEN-GDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLAN 674
Query: 655 ASNEPKPAVPPSS-EKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP 713
+ P PA P + E+ ++++ P+P +GP +N E E L P ++
Sbjct: 675 ENTTPSPAEPTENRERTANENTTPSP----AGP---TENREMTANEKTTLFPAEPTENRE 727
Query: 714 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI 773
+ + TS + E+ ++ P + K S + P + + +
Sbjct: 728 RTANEKTTSSPAEPT---ENGQR----TPFANEKTTSSSAE-PTEHGERTPLANENTTLS 779
Query: 774 PQPPGKGSRQRKAEDKQP--PAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEK 831
P P + +R+R A +K PA + E+ ++++++ + + D + EK
Sbjct: 780 PAGPTE-NRERTANEKTTPFPAEPTENRERTANENTT----PSPAQPTENGDRTPLANEK 834
Query: 832 EIKSQSSSSSSSHKES-SKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD 890
S + + + + + K + S++ ++ P +++ PA+P R R +
Sbjct: 835 TTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANE 894
Query: 891 TCGQDP--PKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNG 948
Q P P + +N K + P + + + + + + T + P + +
Sbjct: 895 KTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDE 954
Query: 949 NSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESE 1008
N + Q ++ D+ A ++ ++ + + + A S +T SE
Sbjct: 955 NLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATAS--STASSTASE 1012
Query: 1009 SQSSKSAYSVYSETVDLIKF-----------IMSLKS-----------------FSDATA 1040
S +A V S + I+F I++L+S TA
Sbjct: 1013 ITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTA 1072
Query: 1041 PTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAP--------S 1092
T C S +A +D + ++ + P S
Sbjct: 1073 STSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVS 1132
Query: 1093 PCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHV 1152
+ T S ++ PS A + S++ + ++ + S P T+ T+S +T S +
Sbjct: 1133 ATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFT-TTSKITAGSEI 1191
Query: 1153 LTAFDLWEQAEALTRK 1168
TA A++ K
Sbjct: 1192 PTASTTDSATTAISTK 1207
Score = 41.6 bits (96), Expect = 0.005
Identities = 97/516 (18%), Positives = 177/516 (34%), Gaps = 85/516 (16%)
Query: 446 SSSAPPSAPQSLPEPVASAH-SSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPE 504
S PP P+S H +++ S+ T +S + SS+D+ E
Sbjct: 129 SGQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHE---------- 178
Query: 505 PEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPP 564
PPT+ + + +P R+ S +DS T+ + S K
Sbjct: 179 -APPTSEE----------------NSSNQGKDPMIRNQRSVDPADSTTTHKESAGK---- 217
Query: 565 KSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGE 624
K + AP++ K +C+KS + R++ T +P++ S +TS
Sbjct: 218 KHITPAPKS--------KINCRKSTTGKSTVTRKSDKT---GRPLEKSMSTLDKTSTSSH 266
Query: 625 REPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALS 684
+ QT K K + A+ + P SEK + + A K L+
Sbjct: 267 KTTTSFHNSGNSQT-KQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLT 325
Query: 685 GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLR 744
N++ E + LT+S P G + + ++R
Sbjct: 326 ---KTTKNIQ----ETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRER---TAN 375
Query: 745 DTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQP---PAGKKHSSEK 801
+ LSP T + + T P P G + ++ PA E+
Sbjct: 376 ENTTLSPAEPTENRERTANENT------APFPAGPTENREMTANENTTLFPAEPTEHGER 429
Query: 802 RSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKES---SKTKPSRPSSQ 858
++++++ + ER + E + S + + H E + K + S++
Sbjct: 430 TANENTTPSPAEPTEHGERTAN--------ENTTPSPAEPTEHGERTPFANDKTTSSSAE 481
Query: 859 SSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDP--PKSASSTKSNHKDSSIPKQR 916
S++ P +++ PA+P R R + P P T +N K + P
Sbjct: 482 STEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSP--- 538
Query: 917 RVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKP 952
VE +R + ++ + P P NG P
Sbjct: 539 -VEPTENRET-----TANEKTTPSPAEPTENGQRTP 568
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 75.5 bits (184), Expect = 3e-13
Identities = 136/693 (19%), Positives = 253/693 (36%), Gaps = 50/693 (7%)
Query: 267 AQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQ--APSESPELKPLPEDYRQQTFEK 324
+ P + PP SL S A + +P ++ +PS S K
Sbjct: 20 SMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPS 79
Query: 325 TDLKVPAKAKL-TKLKMPSQSVEQTYSNEVHCVEEILKEMTHS-WPPPLTAIHTPSTAEP 382
+ +V +KA+ +++ +++ + + +++V C + + THS P S P
Sbjct: 80 SRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQ---RRGTHSRGRTPGRRGSRSSKRSP 136
Query: 383 SKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPE 442
S+ P + H + + +S+ + + + + SDS+ + +
Sbjct: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSY 196
Query: 443 KPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPA 502
+PP S + + P ++ ++ + S SD+ S SSS + + P+
Sbjct: 197 RPPGGSGIGRSSELAVTP----STAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
Query: 503 PEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP 562
E T + S + P +S P R S+ + S +
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
Query: 563 PPKSSSKAPRAPPEAPHPGKRSCQKSPAQ-QEPPQRQTVGTKQPKKPVKASARAGSRTSL 621
+S ++ H RS K +Q Q R+ + P K + + SR+S
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
Query: 622 QGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP-AVPPSSEKKKHKSSLPAPS 680
+ RD P+ K GR ++ + N+ + + S K + +S +P
Sbjct: 373 K-----------ERDHRGSSSPR-KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
Query: 681 KALS-----GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSR 735
KA P A+D R+P + + S+ P + SR+ +A D
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSP--YKARDRSRSRSPNKARDHSRSRSPNKA----RDRS 474
Query: 736 KDRLPLPLRD-TKLLSPLRD-------TPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAE 787
+ R P RD ++L SP ++ +P + + R + S++R+
Sbjct: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR 534
Query: 788 DKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKES 847
+ P ++ S+ RS + + R ERD + ++ + QS SSS S
Sbjct: 535 QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHS 594
Query: 848 SKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPA----LKRSRREADTCGQDPPKSASST 903
P++ S S+ S S+ P+K + S +E+D P+S
Sbjct: 595 RSRSPNKQSGY-SRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK 653
Query: 904 KSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDT 936
+S + SS+ Q R K S S S G T
Sbjct: 654 RSPTRTSSL-SQNRTPSKTSSHSPSTFPSGGQT 685
Score = 66.2 bits (160), Expect = 2e-10
Identities = 118/560 (21%), Positives = 198/560 (35%), Gaps = 89/560 (15%)
Query: 432 SEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSS----------AESESTSDSDSSS 481
S S+ + PS S+ P+A P + S S++ A S ++ S SSS
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
Query: 482 DSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPA-APPEGPRSTEPPRR 540
S +S+ + N P + T ++ D +K S+ + R T R
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
Query: 541 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQR--- 597
P +GS S S P +S R PG S ++P Q+ R
Sbjct: 123 TPGRRGSRSSKRS----------PSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
Query: 598 --------QTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKG 649
+ QP+ K S R + + E + P ++ QT P +
Sbjct: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
Query: 650 RPRAAASNEPK---PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPL 706
P ++S + K + PS EK + + + K+ + + + R H
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYN-----QASTRSRPQSH------ 281
Query: 707 TESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKIT 766
++S+ P S SGS+ R V+ S K R+ +S K
Sbjct: 282 SQSRSPRRSRSGSQK---RTHSRVRSHSWK----------------RNHSRARSRTRKGI 322
Query: 767 LDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKK 826
L + R Q + + + + P G+ H+ + S S + R ERD
Sbjct: 323 LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSH-SHSRSSSKERD----- 376
Query: 827 IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPV--SSSSQKPAKPALKR 884
SSS KES +++ P+ Q P S S+ P K A R
Sbjct: 377 ----------HRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK-ARDR 425
Query: 885 SRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPS 944
SR + +D +S S K+ + S + + SRS ++ + S + PS
Sbjct: 426 SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRS-----PS 480
Query: 945 LPNGNSKPGKPQVKFDKQQA 964
+S+ G P + D +++
Sbjct: 481 KERDHSQLGSPSKERDHRRS 500
Score = 36.2 bits (82), Expect = 0.19
Identities = 78/384 (20%), Positives = 143/384 (37%), Gaps = 42/384 (10%)
Query: 74 KSHTHRLDASENRLGKPKYPLIPDKGSSIPSS----SFHTSVHHQSIHTPASGPLSVGNI 129
+SH+H +S+ R +GSS P S S + Q H+ + P +
Sbjct: 363 RSHSHSRSSSKER---------DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR 413
Query: 130 SHN--PKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCA 187
S + P A+ R+ A+ C S + +DR + R +
Sbjct: 414 SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR 473
Query: 188 SVTDS-APERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSP 246
S + S + ER+ S L S P + P + + SS+ + + ++SP
Sbjct: 474 SRSRSPSKERDHSQLGS------PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSP 527
Query: 247 KDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSE 306
KE + +P + ++ S+S + +++ P +D+
Sbjct: 528 S--------KERQRRQSRSPNKERDRS------QSRSPSEEREHRQSRSPSKERDRRRWR 573
Query: 307 SPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMP-SQSVEQTYSNEVHCVEEILKEMTH 365
SP + R + E+ + + K + P + S E+ +S KE H
Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS----RTPSKEGNH 629
Query: 366 SWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLED 425
S + PS + + P + SS++QN+ TSS + S G ++ +D
Sbjct: 630 SQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQD 689
Query: 426 DLQLSDSEDSDSEQTPEKPPSSSA 449
D Q +D+ S + E+ SSS+
Sbjct: 690 DSQ-ADATTSKATLPGERSSSSSS 712
Score = 35.8 bits (81), Expect = 0.25
Identities = 36/110 (32%), Positives = 43/110 (39%), Gaps = 17/110 (15%)
Query: 842 SSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQK---------PAKPALKRSRREADTC 892
SS K SSK S S SS P PP S S K P KPA R+
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRN----SVM 57
Query: 893 GQDPPKSASSTKSNHKDSSIPKQR-RVEGKG---SRSSSEHKGSSGDTAN 938
KS ST + S+ P R RV K SR S++ + S A+
Sbjct: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 74.7 bits (182), Expect = 5e-13
Identities = 135/616 (21%), Positives = 211/616 (34%), Gaps = 112/616 (18%)
Query: 412 HSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP-------PSAPQSLPEPVASA 464
H + + T + L++ + +ED E E + S P P + P A+A
Sbjct: 32 HQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAA 91
Query: 465 -------HSSSAESESTSDSDSSSDSESESSSSDSEENEPL-ETPAPEPEPPTTNKWQLD 516
++AE D+ S D + + + E + + E EP PP + +
Sbjct: 92 QPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS 151
Query: 517 NWLTKVSQPAAP--PEGPRSTEPPRRHPESKGSSDSATSQEHSE-----------SKDPP 563
P AP PEGPR R P G D+ + E + PP
Sbjct: 152 ------GMPGAPLLPEGPREA---TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
Query: 564 PKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQG 623
K + R + R +S Q PP + Q +P + +AR TS+ G
Sbjct: 203 LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK--ASPAQDGRPPQTAAR--EATSIPG 258
Query: 624 EREPGL--LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP-------AVPPSSEKKKHKS 674
G LP + S + P + G A + P + P+ +K++ S
Sbjct: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
Query: 675 ----------SLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS--------- 715
P GP +D E PE P +G P S
Sbjct: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARM 378
Query: 716 ------GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
G+GS ++A S K L++ LSP TP +++ +
Sbjct: 379 VSKSKDGTGSDD---KKAKTSTRSSAK-----TLKNRPCLSPKHPTPGSSDPLIQPSSPA 430
Query: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKR-------KGEAERDC 822
+ P+PP + +G K K +D +K+A R KG+A
Sbjct: 431 V--CPEPPSSPKHVSSVTSRTGSSGAKEMKLK-GADGKTKIATPRGAAPPGQKGQANATR 487
Query: 823 DNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKE--MLPPPPVSSSSQKPAKP 880
K + S S S + P P + S+ LP PP +++P K
Sbjct: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----TREPKKV 543
Query: 881 ALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQ--RRVEGK-GSRSSSEHKGSSGDTA 937
A+ R+ PPKS SS KS + + +P + V+ K GS + +H+ G
Sbjct: 544 AVVRT----------PPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQ 593
Query: 938 NPFPVPSLPNGNSKPG 953
L N SK G
Sbjct: 594 IINKKLDLSNVQSKCG 609
Score = 67.0 bits (162), Expect = 1e-10
Identities = 83/382 (21%), Positives = 136/382 (35%), Gaps = 36/382 (9%)
Query: 298 DGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
D + +P +SP K P D + P A +P E V +
Sbjct: 223 DVDESSPQDSPPSKASPAQ---------DGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
Query: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQ 417
++ E+ S P + P +F F HV +T N ++ S+ H
Sbjct: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTF------HVE-ITPNVQKEQAHSEEHLGRAA 326
Query: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDS 477
+ E S D+++ PS P +AP+ +PV+ A S S
Sbjct: 327 FPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRG--KPVSRVPQLKARMVSKSKD 384
Query: 478 DSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP 537
+ SD + +S+ S P P+ PT + L + S PA PE P S
Sbjct: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGS---SDPLIQPSSPAVCPEPPSSP-- 439
Query: 538 PRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQR 597
+H S S ++ + + K K+ PR G+ + + PA+ P +
Sbjct: 440 --KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 497
Query: 598 QTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASN 657
+ +P K +G R+ PG GSR +T P T+ P+ A
Sbjct: 498 TPPSSGEPPK-------SGDRSGYSSPGSPG--TPGSRSRT-PSLPTPPTR-EPKKVAVV 546
Query: 658 EPKPAVPPSSEKKKHKSSLPAP 679
P P S++ + + +P P
Sbjct: 547 RTPPKSPSSAKSRLQTAPVPMP 568
Score = 60.1 bits (144), Expect = 1e-08
Identities = 88/365 (24%), Positives = 131/365 (35%), Gaps = 55/365 (15%)
Query: 255 DKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT--AYVRPMDGQDQAPSESPELKP 312
D+ +PQDS + A P PP + ++ ++ P A P+D + +E P +P
Sbjct: 225 DESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
Query: 313 LPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWP---- 368
+ + L+ ++T P+ EQ +S E H P
Sbjct: 285 DGPSVGRAKGQDAPLEFTFHVEIT----PNVQKEQAHSEE-HLGRAAFPGAPGEGPEARG 339
Query: 369 PPL------TAIHTPSTAEPSKFP-------FPTKDSQHVSSVTQNQKQYDTSSKTHSNS 415
P L + PS +P+ P P ++ VS D +KT + S
Sbjct: 340 PSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRS 399
Query: 416 QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA----PPSAPQSLPEPVASAHSSSAES 471
T L++ LS + P PSS A PPS+P+ H SS
Sbjct: 400 SAKT---LKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK---------HVSSV-- 445
Query: 472 ESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG 531
TS + SS E + +D + + P P K Q + P AP
Sbjct: 446 --TSRTGSSGAKEMKLKGADGK----TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 499
Query: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDP----PPKSSSK---APRAPPEAPHPGKRS 584
P S EPP+ S SS + S S+ P PP K R PP++P K
Sbjct: 500 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 559
Query: 585 CQKSP 589
Q +P
Sbjct: 560 LQTAP 564
Score = 45.1 bits (105), Expect = 4e-04
Identities = 118/566 (20%), Positives = 183/566 (32%), Gaps = 135/566 (23%)
Query: 424 EDDLQLSDSEDSDSEQTP-----------EKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
ED + SE SD++ TP E P A +PE ++AE
Sbjct: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPE------GTTAEEA 106
Query: 473 STSDSDSSSDSESESSSSDSEENEPLETP-APEPEPPTTNKWQLDNWLTKVSQPAAP--P 529
D+ S D + + + E + ++ EP PP + + P AP P
Sbjct: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG------MPGAPLLP 160
Query: 530 EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSP 589
EGPR R P G D+ + AP K
Sbjct: 161 EGPREAT---RQPSGTGPEDTEGGRH---------------------APELLKHQLLGDL 196
Query: 590 AQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKG 649
Q+ PP + G ++P GS+ + +R+ + S + K G
Sbjct: 197 HQEGPPLKGAGGKERP----------GSKEEVDEDRD---VDESSPQDSPPSKASPAQDG 243
Query: 650 RPRAAASNEPK--PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
RP A+ E P P + ++P P LS K + E +P +
Sbjct: 244 RPPQTAAREATSIPGFPA-------EGAIPLPVDFLS-----KVSTE---------IPAS 282
Query: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL 767
E GP S R G +D+ PL T + TP Q
Sbjct: 283 EPDGP----SVGRAKG--------QDA-------PLEFT---FHVEITPNVQKEQAHSEE 320
Query: 768 DL-LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKK 826
L + P PG+G E + P G+ S + A +G+ K
Sbjct: 321 HLGRAAFPGAPGEGP-----EARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLK 375
Query: 827 IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSR 886
R+ + K + S K S+++ ++ P P S +P+ PA+
Sbjct: 376 ARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV---- 431
Query: 887 READTCGQDP--PKSASSTKSNHKDSSIPKQRRVEGKGSRSS---------SEHKGSSGD 935
C + P PK SS S SS K+ +++G ++ KG +
Sbjct: 432 -----CPEPPSSPKHVSSVTS-RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANA 485
Query: 936 TANPFPVPSLPNGNSKPGKPQVKFDK 961
T P P P G+P D+
Sbjct: 486 TRIPAKTPPAPKTPPSSGEPPKSGDR 511
Score = 33.5 bits (75), Expect = 1.3
Identities = 65/271 (23%), Positives = 89/271 (32%), Gaps = 59/271 (21%)
Query: 83 SENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEP 142
SE LG+ +P P +G S + P S A PR +P
Sbjct: 318 SEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEP----------SEKQPAAAPRGKP 367
Query: 143 M---PSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELS 199
+ P L A+ + D+ + SS +R C S P
Sbjct: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP-----CLSPKHPTPGSS-D 421
Query: 200 PLISLPSPV----PPLSPIHSNQQTLPRTQGSS----KVHGSSNNSKGYCP-AKSPKDLA 250
PLI SP PP SP H + T RT S K+ G+ +K P +P
Sbjct: 422 PLIQPSSPAVCPEPPSSPKHVSSVT-SRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
Query: 251 VKVHDKETPQDSLVAPAQPPSQTFPP-----------------------PSLPS------ 281
+ + P + AP PPS PP PSLP+
Sbjct: 481 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
Query: 282 KSVAMQQKPTAYVRPMDGQDQ-APSESPELK 311
K VA+ + P + Q AP P+LK
Sbjct: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLK 571
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 74.7 bits (182), Expect = 5e-13
Identities = 113/503 (22%), Positives = 189/503 (37%), Gaps = 78/503 (15%)
Query: 175 KKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSS 234
+K +A GD A++ + P E+ S P + P S T GS K
Sbjct: 2334 RKPSAKAKGDRAATLEEGNPTDEVP---STPLALEPSS-----------TPGSKKSPPEP 2379
Query: 235 NNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYV 294
+ + AK+PK P PA P P P+ + P
Sbjct: 2380 VDKR----AKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPAT-- 2433
Query: 295 RPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVH 354
RP + +A ES P + K D + K K K E +
Sbjct: 2434 RPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ 2493
Query: 355 CVEEILKEMTHSWPPPLTAIHTPSTAEP-------SKFPFPT---KDSQHVSSVTQNQKQ 404
+ +L ++ PP P P ++ P P +DS + S + Q +
Sbjct: 2494 EPKSLLSLGSY---PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAE 2550
Query: 405 YDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKP------------PSSSAPPS 452
D + ++ S+S + S S +++ E+ +K ++S+ +
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610
Query: 453 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK 512
+P S +S+ SSS+ S S+S S SSS S S SSSS S + + + +++
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Query: 513 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR 572
D + S A P P + S+ +A P K++ +A +
Sbjct: 2671 STTDEDSSCSSDDEAAPA-----------PTAGPSAQAAL----------PTKATKQAGK 2709
Query: 573 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY 632
A P A PGK++ +P Q PP QP +P++ A+AG++ S +RE LP
Sbjct: 2710 ARPSAHSPGKKT--PAPQPQAPP-------PQPTQPLQPKAQAGAK-SRPKKREGVHLP- 2758
Query: 633 GSRDQTSKDKPKVKTKGRPRAAA 655
+ + +K + + RP+ AA
Sbjct: 2759 -TTKELAKRQRLPSVENRPKIAA 2780
Score = 70.5 bits (171), Expect = 9e-12
Identities = 102/499 (20%), Positives = 174/499 (34%), Gaps = 72/499 (14%)
Query: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSC---QKS 588
P P + K S D+ ++ + P + ++ P A G R+ + +
Sbjct: 2293 PALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGN 2352
Query: 589 PAQQEP-------PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKD 641
P + P P K P +PV A+A + P + TS
Sbjct: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF-----TSCP 2407
Query: 642 KPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHF 701
P+ + P A S P P + + + K K + A GP + E
Sbjct: 2408 APEPFAE-LPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAE------- 2459
Query: 702 ALVPLTESQGPPHSGSGS-RTSGCRQAVVVQEDSRKD--RLPLPLRDTKLLSPLRDTPPP 758
LV L H G S ++ ++A++++ED + P L P + P
Sbjct: 2460 LLVKLD------HEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEP 2513
Query: 759 QSLMVKITLDLLSRIPQP------------PGKGSRQRKAEDKQPPAGKKHSSEKRSSDS 806
++ K T L++ P P P K ++ ++ + S SS S
Sbjct: 2514 KAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSS 2573
Query: 807 SSKLAKKRKGEAE-------------RDCDNKKIRL-------EKEIKSQSSSSSSSHKE 846
SS + +GE E R+C R S SSSSSSS
Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS 2633
Query: 847 SSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSN 906
SS + S SS SS SSSS + + + E +C D + + T
Sbjct: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGP 2693
Query: 907 HKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKF-----DK 961
+++P + + +R S+ G P P P ++P +P+ + K
Sbjct: 2694 SAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQP---TQPLQPKAQAGAKSRPK 2750
Query: 962 QQADLHMREAKKMKQKAEL 980
++ +H+ K++ ++ L
Sbjct: 2751 KREGVHLPTTKELAKRQRL 2769
Score = 33.9 bits (76), Expect = 0.96
Identities = 86/419 (20%), Positives = 148/419 (35%), Gaps = 68/419 (16%)
Query: 370 PLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQL 429
P T P+T+ F ++++ SS + D+S ++ + E++L+
Sbjct: 1785 PRTLKPKPATSRKQPFCLLLREAEARSSFS------DSSEESFDQDESSEEEDEEEELEE 1838
Query: 430 SDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSS 489
D + + + S P +S +A +S+ S + S S E++ +
Sbjct: 1839 EDEASGGGYRLGARERALS--PGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKA 1896
Query: 490 SDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSD 549
EE + L E + S+ P P++ G S
Sbjct: 1897 RKKEERQSLLGTEFE-------------YTDSESEVKVRKRSPAGLLRPKKGLGEPGPSL 1943
Query: 550 SATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQ------------- 596
+A + ++ P P S KA A + K K P + P+
Sbjct: 1944 AAPTPG---ARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSE 2000
Query: 597 RQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY--GSRDQTSKDKPKVKTKGRPRAA 654
R + P S ++TS + P L P R + KD P+ K KG+
Sbjct: 2001 RIFLHDASAAAPAPVSTAPATKTSRCAKGGP-LSPRKDAGRAKDRKD-PRKKKKGKEAGP 2058
Query: 655 ASNEPKPAVP--PSSEKKKHKSSLPAPSKA---LSGPEPAKDN----------------V 693
+ P P P PS + H SSL A ++ G E K+N
Sbjct: 2059 GAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAE 2118
Query: 694 EDRTPEHFALVPLTESQGPPHSGSGSR-TSGCRQAVVVQEDSRKD--RLPLPLRDTKLL 749
ED P + +E + P G+ R + ++ ++ +D KD R+ +P+ D KLL
Sbjct: 2119 EDFEPNQDS--SFSEDEHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPM-DDKLL 2174
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 74.7 bits (182), Expect = 5e-13
Identities = 151/684 (22%), Positives = 239/684 (34%), Gaps = 97/684 (14%)
Query: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
S A + F +P + S + + K S+ + SS + + + +
Sbjct: 202 SLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEE 261
Query: 438 EQTPEKP---------PSSSAPPSAPQSLPEPVASA---HSSSAESESTSDSDSSSDSES 485
E+ EKP PSS AP PEP A A + SS+
Sbjct: 262 EENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSA---- 317
Query: 486 ESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPP--RRHPE 543
++S E P E P+ P P + ++ T +P +PPEGP + P ++ E
Sbjct: 318 -LTASVEEGGVPGEDPSSRPATPELA--EPESAPTLRVEPPSPPEGPPNPGPDGGKQDGE 374
Query: 544 SKGSSDSATSQEHSESKDPPPKS-SSKAPRAPPEA----PHPGKRSCQKSPAQQEPPQRQ 598
+ + A + + +E P+ +S P A PE P + ++P+ ++ P+R
Sbjct: 375 APPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERS 434
Query: 599 TVGTKQPKKPVKASARAG---------SRTSLQGEREPGLLP--YGSRDQT----SKDKP 643
+P PV G + ER G P G+ T S P
Sbjct: 435 VPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAP 494
Query: 644 KVKTKGRPRAAASNEP----------KPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNV 693
K K RP AAAS P P V P +++ P KA P
Sbjct: 495 KSCLKHRP-AAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPA-GA 552
Query: 694 EDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPL-----------P 742
E PE A E +G S + R V + RLPL
Sbjct: 553 ERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAA 612
Query: 743 LRDTK-LLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKA------EDKQPPAGK 795
L D + L P P P+ L + D R P G ++A + P A +
Sbjct: 613 LDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQE 672
Query: 796 KHSSEKRS----SDSSSKLAKKRKGEAERDCDNKK-----IRLEKEIKSQSSSSSSSHKE 846
SE R+ S+ L+ K + A ++ K +RLE+ +
Sbjct: 673 PAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGT 732
Query: 847 SSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSN 906
+ + +R S K + PP P+SS P KP L+ PP + +
Sbjct: 733 APALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPA---PPDAGPGEREP 789
Query: 907 HKDSSIPKQRRVEGKGSRS---SSEHKGSSGDTANPF----------PVPSLPNGNSKPG 953
K+ ++R + +S ++ G+ G A P+ + PN KPG
Sbjct: 790 RKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPG 849
Query: 954 KPQVKFDK-QQADLHMREAKKMKQ 976
+K + +QA + R + +KQ
Sbjct: 850 ARTLKSEPGKQAKVPERGQEPVKQ 873
Score = 55.1 bits (131), Expect = 4e-07
Identities = 123/537 (22%), Positives = 195/537 (36%), Gaps = 99/537 (18%)
Query: 438 EQTPEKPPSSSAPPSAPQS-----LPEPVASAHSSSAESESTS--DSDSSSDSESESSSS 490
+Q E PP+ P+ ++ PE VAS ++ T+ ++D ++ SE+ S+
Sbjct: 370 KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARD 429
Query: 491 DSEENEPLET----------------PAPEPE------PPTTNKWQLDNWLTKVSQPAAP 528
E + P E PAPEPE P + + T+ S AP
Sbjct: 430 GPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489
Query: 529 -PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPK---SSSKAPRAPPEAPHPGKRS 584
P P+S +H + S A S + ++ PP + S A A PE P +
Sbjct: 490 SPPAPKSC---LKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAE 546
Query: 585 CQKSPAQQEPPQRQT----VGTKQPKKPVKASARAGSRTSLQG--EREPGLLPYGS---- 634
+ A++ P+R+ + KK +S RA R + ER G LP
Sbjct: 547 APPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPV 606
Query: 635 -RDQTSKD------KPKVKTKGRPRAAASNEPKP----AVPPSSEKKKHKSSLPAPSKAL 683
R + + D +P+ K PR A P+ A P+ +K + + AP
Sbjct: 607 WRSEAALDDLQGLPEPQ-HAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTRE 665
Query: 684 SGP---EPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQ--AVVVQEDS---- 734
P EPA EDR P L T G+ G ++ A V E S
Sbjct: 666 PCPAAQEPAPS--EDRNPFPVKL-RSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVL 722
Query: 735 -RKDRLPL----PLRDTKLLS-----------PLRDTP--PPQSLMVKITLDLLSRIPQP 776
++++ PL LR T+ S PL P P + L+ T L P P
Sbjct: 723 PKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFT---LPHQPAP 779
Query: 777 PGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQ 836
P G +R+ K+P +K + + S A + + + +K +
Sbjct: 780 PDAGPGEREPR-KEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTL 838
Query: 837 SSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQK-------PAKPALKRSR 886
+ K ++T S P Q+ E P + + P KPA+ R +
Sbjct: 839 DQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQ 895
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 74.3 bits (181), Expect = 6e-13
Identities = 180/845 (21%), Positives = 286/845 (33%), Gaps = 153/845 (18%)
Query: 193 APERELSPLIS--LPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA 250
+PE SP S + + VPP+ P S ++ T S +K Y P L
Sbjct: 1633 SPESAQSPSPSGDVRASVPPVLPSSSGKKN-DTTSARELSPSSLKMNKSYL--LEPWFLP 1689
Query: 251 VKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPEL 310
+ +P SL P + P P+ S M+ P Q SP+
Sbjct: 1690 PSRGLQNSPAVSLPDPEFKRDRKGPHPTARSPGTVMESNP----------QQREGSSPKH 1739
Query: 311 KPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPP 370
+ D + T +L P A+ + +P E + S E + L+E + PP
Sbjct: 1740 QDHTTDPKLLTCLGQNLHSPDLAR-PRCPLPP---EASPSRE----KPGLRESSERGPPT 1791
Query: 371 LTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLS 430
+ + + A+ + P + + N K + +TH + T +M +
Sbjct: 1792 ARSERSAARADTCREPSMELCFPETAKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGG 1851
Query: 431 DSEDSDSEQTPEKPPSS-----SAPPSAPQSL--------PEPVA-----SAHSSSAESE 472
+ D PP SA + L P+P A S ESE
Sbjct: 1852 KTNHKDGPGEARPPPRDNSSLHSAGIPCEKELGKVRRGVEPKPEALLARRSLQPPGIESE 1911
Query: 473 STSDSDSSSDSESESSSSDSEENEPLET-PAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG 531
+ S + + + + +PL+ P+ P PP T K +S PAA
Sbjct: 1912 KSEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAK--------DLSSPAARQHC 1963
Query: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDPPP------KSSSKAPRAPPEAPHPGKRSC 585
+ R P +K S T++ S +DPP +SSS PR P+ P +
Sbjct: 1964 SSPSHASGREPGAKPS----TAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHP 2019
Query: 586 QKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY--GSRDQTSKD-- 641
+S + Q+P T G + + + S+R G S G P + P GS+++ S
Sbjct: 2020 DRSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSKSG---PDVFPATPGSQNKASDGIG 2076
Query: 642 -------------------KPKVKTKGRPRAAASNE---PKPAVPPSSEKKKHKSSLPAP 679
KP+ + GRP P+P P SE K S
Sbjct: 2077 QGEGGPSVPLHTDRAPLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSEPADQKLSAVGE 2136
Query: 680 SKALSGPEPAKDNVED--RTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKD 737
+ LS P V+D + +S P + + R G + + + D
Sbjct: 2137 KQTLSPKHPKPSTVKDCPTLCKQTDNRQTDKSPSQPAANTDRRAEGKKCTEALYAPAEGD 2196
Query: 738 RLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG-SRQRKAEDKQPPAGKK 796
+L L + L+ P + + K P+ GKG Q+ + P G K
Sbjct: 2197 KLEAGLSFVHSENRLKGAERPAAGVGK-------GFPEARGKGPGPQKPPTEADKPNGMK 2249
Query: 797 HSSE-------------KRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSS 843
S ++S SS + R G E + K + S
Sbjct: 2250 RSPSATGQSSFRSTALPEKSLSCSSSFPETRAGVREASAASSDTSSAKAAGGMLELPAPS 2309
Query: 844 HKESSKTKPS-RPSSQSSKKEMLP-------------PPPVSSSSQKPAKPALKRSRREA 889
+++ K +P+ + +K + LP P P + AL +
Sbjct: 2310 NRDHRKAQPAGEGRTHMTKSDSLPSFRVSTLPLESHHPDPNTMGGASHRDRALSVTATVG 2369
Query: 890 DTCGQDP-------------------PKSASSTK-----SNHKDSSIPKQRRVEGKGSRS 925
+T G+DP P A +T SN KD + +QRR GK S
Sbjct: 2370 ETKGKDPAPAQPPPARKQNVGRDVTKPSPAPNTDRPISLSNEKD-FVVRQRR--GKESLR 2426
Query: 926 SSEHK 930
SS HK
Sbjct: 2427 SSPHK 2431
Score = 56.2 bits (134), Expect = 2e-07
Identities = 208/1020 (20%), Positives = 341/1020 (33%), Gaps = 207/1020 (20%)
Query: 80 LDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPR 139
L + E+ G P + L P P+ S+ + TP + + S +P + P
Sbjct: 1102 LSSGESLPGSPTHSLSPRS----PTPSYRS--------TPDFPSGTNSSQSSSPSSSAPN 1149
Query: 140 TEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELS 199
+ P S H + P + H +LG + + S K SA LS
Sbjct: 1150 S-PAGSGHIR----PSTLHGLAPKLGGQRYRSGRRK----------------SAGNIPLS 1188
Query: 200 PLISLPSPVP-PLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKET 258
PL PSP P P SP S L + G+SK+ + SK + P + + V+ E
Sbjct: 1189 PLARTPSPTPQPTSPQRSPSPLLGHSLGNSKI-AQAFPSKMHSPPTIVRHI-VRPKSAEP 1246
Query: 259 PQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDY- 317
P+ L+ Q + P K + ++ + ++Q+ E+P L+ L E+
Sbjct: 1247 PRSPLLKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQSQREAP-LQSLDENVC 1305
Query: 318 ------RQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPL 371
R + E+ LK P K+ + +SV+ +++ +++ + +P
Sbjct: 1306 DVPPLSRARPVEQGCLKRPVSRKVGR----QESVDDLDRDKLKA--KVVVKKADGFP--- 1356
Query: 372 TAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLE----DDL 427
+ + S P ++ + + + +K+ + S++ + +SM E L
Sbjct: 1357 ---EKQESHQKSHGPGSDLENFALFKLEEREKKVYPKAVERSSTFENKASMQEAPPLGSL 1413
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDS-DSSSDSESE 486
S + E S P+ + A + + S D + E
Sbjct: 1414 LKDALHKQASVRASEGAMSDGRVPAEHRQGGGDFRRAPAPGTLQDGLCHSLDRGISGKGE 1473
Query: 487 SSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKG 546
+ S+ E L + + + + L P P+ T H G
Sbjct: 1474 GTEKSSQAKELLRCEKLDSKLANIDYLRKKMSLEDKEDNLCPVLKPKMT--AGSHECLPG 1531
Query: 547 SSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQP- 605
+ T + ++PPP S S RA + H + S + R GT++P
Sbjct: 1532 NPVRPTGGQ----QEPPPASES---RAFVSSTHAAQMSAVSFVPLKALTGRVDSGTEKPG 1584
Query: 606 -KKPVKASARAGSRTSLQGEREPGLLPY-GSRDQTSKDKPKVKTKGRPRAAASNEPKPA- 662
P ++ S L+G L P G+ D P+ P ++ P P+
Sbjct: 1585 LVAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPESAQSPSPSG 1644
Query: 663 --------VPPSSEKKK----------------HKSSLPAP-----------SKALSGPE 687
V PSS KK +KS L P S A+S P+
Sbjct: 1645 DVRASVPPVLPSSSGKKNDTTSARELSPSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPD 1704
Query: 688 PAKDNVEDRTPEHFALVPLTESQGPPHSGSGS-----------RTSGCRQAVVVQEDSRK 736
P + + + P A P T + P GS + C + D +
Sbjct: 1705 P-EFKRDRKGPHPTARSPGTVMESNPQQREGSSPKHQDHTTDPKLLTCLGQNLHSPDLAR 1763
Query: 737 DRLPLPLRDTKLLSPLRDTP---------PPQSLMVKI---------------------- 765
R PLP SP R+ P PP + +
Sbjct: 1764 PRCPLPPE----ASPSREKPGLRESSERGPPTARSERSAARADTCREPSMELCFPETAKT 1819
Query: 766 ---TLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSS-----------EKRSSDSSSKLA 811
+ +LLS P ++ + E P GK + + S S+
Sbjct: 1820 SDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGGKTNHKDGPGEARPPPRDNSSLHSAGIPC 1879
Query: 812 KKRKGEAERDCDNKKIRL-----------EKEIKSQSSSSSSSHKESSKTKPSRPSSQSS 860
+K G+ R + K L E E + SS S K+ +K +
Sbjct: 1880 EKELGKVRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKEQPLQR 1939
Query: 861 KKEMLPPPPV---------------SSSSQKPAKPALKRSRREADTCGQDPPK--SASST 903
+PPPP+ S S +P K S E + QDPPK +A S
Sbjct: 1940 HPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAHSE 1999
Query: 904 KSNHK-----DSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVK 958
S+HK D PK + + RS S K S G T P G+S+ GK K
Sbjct: 2000 SSSHKPRPGPDPGPPKTKHPD----RSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSK 2055
Score = 36.6 bits (83), Expect = 0.15
Identities = 35/169 (20%), Positives = 66/169 (39%), Gaps = 26/169 (15%)
Query: 401 NQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEP 460
N + ++ + S+ S + +++ + + E + +K S++ P + S
Sbjct: 701 NDEDFNVEIRQFSSCSHRFSKVFSSIDRITQNSAEEKEDSVDKTKSTTLPSTETLSW--- 757
Query: 461 VASAHSSSAESESTSDSDSSSDSESESS--------SSDSEENEPLETPAPEPEPPTTNK 512
+S +S + +++ SD+ S+ SS S++ E++E P E P
Sbjct: 758 -SSEYSEMQQLSTSNSSDTESNRHKLSSGLLPKLAISTEGEQDEAASCPGDPHEEP---- 812
Query: 513 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561
+PA PPE EP P S SS + + SE D
Sbjct: 813 ----------GKPALPPEECAQEEPEVTTPASTISSSTLSVGSFSEHLD 851
Score = 32.0 bits (71), Expect = 3.7
Identities = 81/398 (20%), Positives = 136/398 (34%), Gaps = 61/398 (15%)
Query: 547 SSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPK 606
S S S S + P+S + + R+ P+ P S SP+ P G +P
Sbjct: 1101 SLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPS 1160
Query: 607 KPVKASARAGSRTSLQGERE-PGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPP 665
+ + G + G R+ G +P +T P+ + R P P +
Sbjct: 1161 TLHGLAPKLGGQRYRSGRRKSAGNIPLSPLARTPSPTPQPTSPQR-------SPSPLLGH 1213
Query: 666 SSEKKKHKSSLPAPSKALSGPEPAKDNVEDRT--PEHFALVPLTESQG--PPHSGSGSR- 720
S K + PSK S P + V ++ P L+ +S+ P GS +
Sbjct: 1214 SLGNSKIAQAF--PSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKH 1271
Query: 721 -TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGK 779
S V QE+ ++++ L + D PP LSR +P +
Sbjct: 1272 LCSRKHSLEVTQEEVQREQSQREAPLQSLDENVCDVPP------------LSR-ARPVEQ 1318
Query: 780 GSRQRKAEDKQPPAGKKHSSEKRSSD--SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQS 837
G +R K G++ S + D + + KK G E+
Sbjct: 1319 GCLKRPVSRK---VGRQESVDDLDRDKLKAKVVVKKADGFPEK----------------Q 1359
Query: 838 SSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPP 897
S SH S + +++ + P V SS K +++ + PP
Sbjct: 1360 ESHQKSHGPGSDLENFALFKLEEREKKVYPKAVERSSTFENKASMQEA----------PP 1409
Query: 898 KSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGD 935
+ + HK +S+ G R +EH+ GD
Sbjct: 1410 LGSLLKDALHKQASVRASEGAMSDG-RVPAEHRQGGGD 1446
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 73.2 bits (178), Expect = 1e-12
Identities = 129/614 (21%), Positives = 207/614 (33%), Gaps = 115/614 (18%)
Query: 412 HSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP-------PSAPQSLPEPVASA 464
H + + T + L++ + +ED E E + S P P + P A+A
Sbjct: 32 HQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAA 91
Query: 465 -------HSSSAESESTSDSDSSSDSESESSSSDSEENEPL-ETPAPEPEPPTTNKWQLD 516
++AE D+ S D + + + E + + E EP PP + +
Sbjct: 92 QPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS 151
Query: 517 NWLTKVSQPAAP--PEGPRSTEPPRRHPESKGSSDSATSQEHSE-----------SKDPP 563
P AP PEGPR R P G D+ + E + PP
Sbjct: 152 ------GMPGAPLLPEGPREA---TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
Query: 564 PKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQG 623
K + R + R +S Q PP + Q +P + +AR TS+ G
Sbjct: 203 LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK--ASPAQDGRPPQTAAR--EATSIPG 258
Query: 624 EREPGL--LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP-------AVPPSSEKKKHKS 674
G LP + S + P + G A + P + P+ +K++ S
Sbjct: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
Query: 675 ----------SLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS--------- 715
P GP +D E PE P +G P S
Sbjct: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARM 378
Query: 716 ------GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
G+GS ++A S K L++ LSP TP +++
Sbjct: 379 VSKSKDGTGSDD---KKAKTSTRSSAK-----TLKNRPCLSPKHPTPGSSDPLIQ----- 425
Query: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSE--KRSSDSSSKLAKKRKGEAERDCDNKKI 827
P P A +PP+ KH S R+ S +K K + + + +
Sbjct: 426 ----PSSP--------AVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRG 473
Query: 828 RLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRR 887
K Q++++ K + P P S ++K+ PPP S++ P +
Sbjct: 474 AAPPGQKGQANATRIPAK--TPPAPKTPPSSATKQVQRRPPPAGPRSERGEPP------K 525
Query: 888 EADTCGQDPPKSASSTKSNHKDSSIP-----KQRRVEGKGSRSSSEHKGSSGDTANPFPV 942
D G P S + S + S+P + ++V + S S P P+
Sbjct: 526 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 585
Query: 943 PSLPNGNSKPGKPQ 956
P L N SK G +
Sbjct: 586 PDLKNVKSKIGSTE 599
Score = 65.5 bits (158), Expect = 3e-10
Identities = 92/384 (23%), Positives = 146/384 (38%), Gaps = 51/384 (13%)
Query: 255 DKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT--AYVRPMDGQDQAPSESPELKP 312
D+ +PQDS + A P PP + ++ ++ P A P+D + +E P +P
Sbjct: 225 DESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
Query: 313 LPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLT 372
+ + L+ ++T P+ EQ +S E + + P
Sbjct: 285 DGPSVGRAKGQDAPLEFTFHVEIT----PNVQKEQAHSE-----EHLGRAAFPGAPGEGP 335
Query: 373 AIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQY----DTSSKTHSNSQQGTSSMLEDDLQ 428
PS E +K + S+ + K ++ S S+ GT S DD +
Sbjct: 336 EARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGS---DDKK 392
Query: 429 LSDSEDSDSEQTPEKP--------PSSSAP---PSAPQSLPEPVAS-AHSSSAESESTSD 476
S S ++ +P P SS P PS+P PEP +S H SS TS
Sbjct: 393 AKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSV----TSR 448
Query: 477 SDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRS-T 535
+ SS E + +D + + P P K Q + P AP P S T
Sbjct: 449 TGSSGAKEMKLKGADGK----TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSAT 504
Query: 536 EPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAP-HPGKRSCQKSPAQQEP 594
+ +R P G + PPKS ++ + P +P PG RS ++P+ P
Sbjct: 505 KQVQRRPPPAGP---------RSERGEPPKSGDRSGYSSPGSPGTPGSRS--RTPSLPTP 553
Query: 595 PQRQTVGTKQPKKPVKASARAGSR 618
P R+ + P K+ + A SR
Sbjct: 554 PTREPKKVAVVRTPPKSPSSAKSR 577
Score = 55.8 bits (133), Expect = 2e-07
Identities = 112/493 (22%), Positives = 167/493 (33%), Gaps = 91/493 (18%)
Query: 378 STAEPSKF-PFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSD 436
+T +PS P T+ +H + ++Q D + G ++ + D D
Sbjct: 166 ATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD 225
Query: 437 SEQTPEKPPSSSAPPS---APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSE 493
+ PPS ++P PQ+ S AE D S +E +S+ +
Sbjct: 226 ESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPD 285
Query: 494 ---------ENEPLETPAPEPEPPTTNKWQL--DNWLTKVSQPAAPPEGPRSTEP----- 537
++ PLE P K Q + L + + P AP EGP + P
Sbjct: 286 GPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
Query: 538 -----------------PRRHPESKGSSDSAT----SQEHSESKDPPPKSSSKA------ 570
PR P S+ A S++ + S D K+S+++
Sbjct: 346 TKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLK 405
Query: 571 --PRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPG 628
P P+ P PG P Q P V + P P S+ SRT G +E
Sbjct: 406 NRPCLSPKHPTPGS----SDPLIQ--PSSPAVCPEPPSSPKHVSS-VTSRTGSSGAKEMK 458
Query: 629 LLPYGSRDQ--TSKDKPKVKTKGRPRAA---ASNEPKPAVPPSSEKKKHKSSLPAPSKAL 683
L + + T + KG+ A A P P PPSS K+ +
Sbjct: 459 LKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRR-------- 510
Query: 684 SGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPL-P 742
P PA P +E PP SG S S SR LP P
Sbjct: 511 --PPPAG--------------PRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
Query: 743 LRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAED---KQPPAGKKHSS 799
R+ K ++ +R TPP K L + +P P K + + K P G K
Sbjct: 555 TREPKKVAVVR-TPPKSPSSAKSRLQ-TAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI 612
Query: 800 EKRSSDSSSKLAK 812
+ D S+ +K
Sbjct: 613 INKKLDLSNVQSK 625
Score = 42.0 bits (97), Expect = 0.004
Identities = 117/563 (20%), Positives = 181/563 (32%), Gaps = 135/563 (23%)
Query: 424 EDDLQLSDSEDSDSEQTP-----------EKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
ED + SE SD++ TP E P A +PE ++AE
Sbjct: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPE------GTTAEEA 106
Query: 473 STSDSDSSSDSESESSSSDSEENEPLETP-APEPEPPTTNKWQLDNWLTKVSQPAAP--P 529
D+ S D + + + E + ++ EP PP + + P AP P
Sbjct: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG------MPGAPLLP 160
Query: 530 EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSP 589
EGPR R P G D+ + AP K
Sbjct: 161 EGPREAT---RQPSGTGPEDTEGGRH---------------------APELLKHQLLGDL 196
Query: 590 AQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKG 649
Q+ PP + G ++P GS+ + +R+ + S + K G
Sbjct: 197 HQEGPPLKGAGGKERP----------GSKEEVDEDRD---VDESSPQDSPPSKASPAQDG 243
Query: 650 RPRAAASNEPK--PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
RP A+ E P P + ++P P LS K + E +P +
Sbjct: 244 RPPQTAAREATSIPGFPA-------EGAIPLPVDFLS-----KVSTE---------IPAS 282
Query: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL 767
E GP S R G +D+ PL T + TP Q
Sbjct: 283 EPDGP----SVGRAKG--------QDA-------PLEFT---FHVEITPNVQKEQAHSEE 320
Query: 768 DL-LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKK 826
L + P PG+G E + P G+ S + A +G+ K
Sbjct: 321 HLGRAAFPGAPGEGP-----EARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLK 375
Query: 827 IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSR 886
R+ + K + S K S+++ ++ P P S +P+ PA+
Sbjct: 376 ARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV---- 431
Query: 887 READTCGQDP--PKSASSTKSNHKDSSIPKQRRVEGKGSRSS---------SEHKGSSGD 935
C + P PK SS S SS K+ +++G ++ KG +
Sbjct: 432 -----CPEPPSSPKHVSSVTS-RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANA 485
Query: 936 TANPFPVPSLPNGNSKPGKPQVK 958
T P P P QV+
Sbjct: 486 TRIPAKTPPAPKTPPSSATKQVQ 508
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 72.8 bits (177), Expect = 2e-12
Identities = 174/759 (22%), Positives = 256/759 (33%), Gaps = 160/759 (21%)
Query: 82 ASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTE 141
AS LG+ P S PSSS T H QS T S ++ + + +
Sbjct: 388 ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGS------EGQ 441
Query: 142 PMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELS-P 200
P S + S PP G G GS G A+ S+ S S
Sbjct: 442 PESSTASNSVVPPPQ--------GGSGRGSP---SGGSTAEASDTLSIRSSGQLSGRSVS 490
Query: 201 LISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ 260
L L P PP HS Q +G P L K K+ PQ
Sbjct: 491 LRKLKRPPPPPRRTHSLHQ------------------RGLAVPDGPLGLPPKPERKQQPQ 532
Query: 261 -----------DSLVAPAQP-PSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESP 308
+ AP P P+ ++ P P S + P + P G + S +P
Sbjct: 533 LPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS-SQSGTP 591
Query: 309 ELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEE---------- 358
L P + + P ++T L+ P SV + ++ +
Sbjct: 592 TLPP--KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649
Query: 359 ILKEMTHSWP-PPLTAIHTPSTAEPSK--FPFPTKDSQHVSSVTQNQKQYDTSSKTHSNS 415
IL + + PP + P + PSK P P + +V +S +
Sbjct: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709
Query: 416 QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTS 475
Q T + L++ +S + P PP S PP P PE V A S+S +E
Sbjct: 710 PQTTLTPLQESPVISKDQSP-----PPSPPPSYHPPPPPTKKPEVVVEAPSASETAE--- 761
Query: 476 DSDSSSDSESESSSSDSEENEPLETPA-PEPEPPTTNKWQL--------DNWLTKVSQPA 526
EPL+ P P P PP + L + V+ P
Sbjct: 762 --------------------EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASP- 800
Query: 527 APPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP-PEAPHPGKRSC 585
P GP + P + SS +A + S DPPP AP AP P + PG +
Sbjct: 801 -EPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP-----APPAPAPASSAPGHVA- 853
Query: 586 QKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKV 645
+ PQ++ VG + P + A T P LL ++
Sbjct: 854 -------KLPQKEPVGCSKGGGPPREDVGAPLVT-------PSLL----------QMVRL 889
Query: 646 KTKGRPRAAASNEPKPAVPPSSEKKK-------HKSSLPAPSKALSGPEPAKDNVEDRTP 698
++ G P A P PA+ PS+ +K S +PAPS L V +
Sbjct: 890 RSVGAPGGA----PTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAA------VRLKAC 939
Query: 699 EHFALVPLTESQ--GPPHSGSGSRTSGCRQA-VVVQEDSRKDRLPLPLRDTKLLSPLRDT 755
A L+ +Q GPP + S A + + SRK +L P +SP
Sbjct: 940 SLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP------VSPETQA 993
Query: 756 PPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAG 794
++L+ ++ R PQ P K + ++P G
Sbjct: 994 DLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG 1032
Score = 60.1 bits (144), Expect = 1e-08
Identities = 107/447 (23%), Positives = 162/447 (36%), Gaps = 84/447 (18%)
Query: 441 PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLET 500
P+ P S PPS P+S P P A A ++ A S++D+ +S + P T
Sbjct: 664 PKVPAPFSPPPSKPRS-PNPAAPALAAPAVVPGPV---STTDASPQSPPT------PQTT 713
Query: 501 PAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESK 560
P E P +K Q S P +PP PP + PE + SA+ +
Sbjct: 714 LTPLQESPVISKDQ--------SPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765
Query: 561 DPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQ--TVGTKQPKKPVKASARAGSR 618
DP P PP AP S P PP+ +V + +P P +GS
Sbjct: 766 DP------NWPPPPPPAPEEQDLSMADFP----PPEEAFFSVASPEPAGP------SGS- 808
Query: 619 TSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP---PSSEKKKHKSS 675
P L+ + +S +++ G P +P PA P P+S H +
Sbjct: 809 --------PELVSSPAASSSSATALQIQPPGSP------DPPPAPPAPAPASSAPGHVAK 854
Query: 676 LPA--PSKALSGPEPAKDNVEDR--TPEHFALVPLTESQGP-----PHSGSGSRTSGCRQ 726
LP P G P +++V TP +V L P P G + R+
Sbjct: 855 LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914
Query: 727 AVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKA 786
A+ R +P P S L ++ + + L S P P +
Sbjct: 915 AL----SGRASPVPAPS------SGLHAAVRLKACSLAASEGLSSAQPNGPPEA------ 958
Query: 787 EDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKE 846
+ +PP ++ S S KL +R E D ++ L E++S S +
Sbjct: 959 -EPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR-NLVAELRSISEQRPP---Q 1013
Query: 847 SSKTKPSRPSSQSSKKEMLPPPPVSSS 873
+ K P P + K + PPP S S
Sbjct: 1014 APKKSPKAPPPVARKPSVGVPPPASPS 1040
Score = 47.0 bits (110), Expect = 1e-04
Identities = 97/453 (21%), Positives = 142/453 (31%), Gaps = 93/453 (20%)
Query: 186 CASVTDSAPERELSPLI--------------SLPSPV-PPLSPIHSNQQTLPRTQGSSKV 230
C+S +D AP P I +P+P PP S S P + V
Sbjct: 634 CSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693
Query: 231 HGSSNNSKGYCPAKSPKDLAVKVHDKETP---QDSLVAPAQPPSQTFPPPSLPSKSVAMQ 287
G + + P P +E+P +D P+ PPS PPP V ++
Sbjct: 694 PGPVSTTDA-SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVE 752
Query: 288 QKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKM----PSQ 343
+ QD P+ P P PE+ Q D P +A + PS
Sbjct: 753 APSASETAEEPLQD--PNWPPPPPPAPEE---QDLSMADFPPPEEAFFSVASPEPAGPSG 807
Query: 344 SVEQTYSNEVHCVEEILKEMTHSW---PPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQ 400
S E S ++ PPP P+++ P HV+ + Q
Sbjct: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPG----------HVAKLPQ 857
Query: 401 NQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEP 460
+ + G + LQ+ S P P+ + PSAPQ
Sbjct: 858 KEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLR---SVGAPGGAPTPALGPSAPQKPLRR 914
Query: 461 VASAHSSSAESESTS-----DSDSSSDSESESSSSDSEENEPLETPAPEPEPPTT----- 510
S +S + S+ + S + SE SS P P P P +T
Sbjct: 915 ALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIF 974
Query: 511 ----NKWQLDNWLTKVSQ-------------------PAAPPEGPRSTEPPRRHPESKGS 547
K QL+ ++ +Q P AP + P++ P R P
Sbjct: 975 SKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKP----- 1029
Query: 548 SDSATSQEHSESKDPPPKSSSKAPRAPPEAPHP 580
S PP +S PRA P P
Sbjct: 1030 -----------SVGVPPPASPSYPRAEPLTAPP 1051
Score = 35.4 bits (80), Expect = 0.33
Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 5/125 (4%)
Query: 837 SSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG--- 893
SSS + SH +SS T S S+ SSK P S++S P S R + + G
Sbjct: 411 SSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTA 470
Query: 894 --QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSK 951
D SS + + + S+ K +R R+ S H+ P +P P +
Sbjct: 471 EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQ 530
Query: 952 PGKPQ 956
P P+
Sbjct: 531 PQLPR 535
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 72.4 bits (176), Expect = 2e-12
Identities = 200/970 (20%), Positives = 303/970 (31%), Gaps = 189/970 (19%)
Query: 46 KTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPL---------IP 96
K A+ +E S+ N G EE+ E S +++ + +E L +P+ P +
Sbjct: 55 KKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLN 114
Query: 97 DKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPK-MAQPRTEPM--PSLHAKSCGP 153
D GSS P ++S P SV N S + ++Q P P L S P
Sbjct: 115 DDGSSDPRD---IDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQP 171
Query: 154 PDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSP 213
PDS + +S G H ++ + P P P P L P
Sbjct: 172 PDSTPRQPE--------ASFEPHPSVTPTGYHAPMEPPTSRMFQAPP--GAPPPHPQLYP 221
Query: 214 -----IHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDL-------AVKVHDKETPQD 261
+ S P+ G++ G N K + P +P + A TP
Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVG 281
Query: 262 SLVAPAQPPSQTFP--------PPSLPSKSVAMQQKPTAYVRP--------------MDG 299
P+ PP FP PP+L + A P +P M G
Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
Query: 300 QDQAPSESPELKPLPEDY--RQQTFEKTDLKVP-AKAKLTKLKMPSQSVEQTYSNEVHCV 356
P + P L P P + ++ P + + + S S + S
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 357 EEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQ 416
+ L HS+PPP T++ + +P K+ P+ SQ V S +SN+
Sbjct: 402 SQALPSYPHSFPPP-TSLSVSN--QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
G PPS+ A +A PV++ H + +
Sbjct: 459 PGPF-----------------------PPSTGAQSTAHP----PVSTHHHHHQQQQQQQQ 491
Query: 477 SDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTE 536
+ + +S P PP L+ + + P A S
Sbjct: 492 QQQQQQQQQQQHHGNSG-----------PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 537 PPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEP-- 594
P P S S + PP SSS + + + +P Q P
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 595 -PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
P TV T + A S + PG PYG R + G +
Sbjct: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR---------APSPGAYKT 651
Query: 654 AASNEPKPAVPPS----SEKKKHKSSLPA------PSKALSGPEPAKDNVEDRTPEHFAL 703
A KP PPS + +S PA P GP P P
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS-LPP 710
Query: 704 VPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMV 763
P + GPP S + + E+ P+P P R PP ++
Sbjct: 711 PPAAPASGPPLSATQIKQEPA-------EEYETPESPVP--------PARSPSPPPKVV- 754
Query: 764 KITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSD-----SSSKLAKKRKGEA 818
+P + +R K D+ +S RS SKLAKKR
Sbjct: 755 --------DVPSHASQSARFNKHLDRG------FNSCARSDLYFVPLEGSKLAKKRADLV 800
Query: 819 ERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSK-----KEMLPPPPVSSS 873
E K+R E E +++ +E K + + + +E P S
Sbjct: 801 E------KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSL 854
Query: 874 SQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSS 933
P +P + P SA +T + P R + S + H S
Sbjct: 855 GPVPHRPPFE-------------PGSAVATVPPYLGPDTPALRTL----SEYARPHVMSP 897
Query: 934 GDTANPFPVP 943
G+ +PF VP
Sbjct: 898 GNRNHPFYVP 907
Score = 60.1 bits (144), Expect = 1e-08
Identities = 127/617 (20%), Positives = 197/617 (31%), Gaps = 70/617 (11%)
Query: 368 PPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427
P P + + A P + D + S +K + T ++QG S
Sbjct: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSE------ 74
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
++S+SE S+ P+K + Q LP P + + S + S +D SS + +
Sbjct: 75 EISESE-SEETNAPKKTKTE-------QELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQ 126
Query: 488 SSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGS 547
D+ P E + + L + P PP P S +PP P +
Sbjct: 127 ---DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP--PPLFPPSPQPPDSTPRQPEA 181
Query: 548 S----DSATSQEHSESKDPPPKSSSKAPR-APPEAP--HPGKRSCQKSPAQQEPPQRQTV 600
S S T + +PP +AP APP P +PG S P
Sbjct: 182 SFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241
Query: 601 -------GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
G KQ P + + S S +P P G + S P P
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPA----NFPHV 297
Query: 654 AASNEPKPAV---------PPSSEKKKHKSSLPAP---SKALSGPEPAKDNVEDRTPEHF 701
+ P PA+ PP + LP+P + + G P + P
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 702 ALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL-SPLRDTPPPQS 760
+L P + S P +S A S P ++ L S PPP S
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 761 LMV-----KITLDLL------SRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809
L V K T L S+ P PP R + P G S S +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP--GPFPPSTGAQSTAHPP 475
Query: 810 LAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
++ ++ ++ + +++ + Q +S + P S P
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535
Query: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
+ S P PA + Q P + S++ SS +GS S
Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST-------SQGSYPCSHP 588
Query: 930 KGSSGDTANPFPVPSLP 946
S G P+P P +P
Sbjct: 589 SPSQGPQGAPYPFPPVP 605
Score = 55.1 bits (131), Expect = 4e-07
Identities = 117/525 (22%), Positives = 168/525 (32%), Gaps = 80/525 (15%)
Query: 463 SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTK- 521
+A + E ST + SE S S E N P +T + P + LD+ +
Sbjct: 53 TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRS 112
Query: 522 -----VSQPAAPPEGPRSTEPPRRHP---ESKGSSDSATSQEHSESKDPPPKSSSKAPRA 573
S P + RST P P E+ S S SQ + PPP
Sbjct: 113 LNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF------- 165
Query: 574 PPEAPHPGKRSCQKSPAQQEP-PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY 632
P +P P + ++ A EP P G P +P ++R P L P
Sbjct: 166 -PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP--PTSRMFQAPPGAPPPHPQLYPG 222
Query: 633 GSRDQTSKDKPKVKTKGRPRAAASNEPK------PAVPPSSEKKKHKSSLP---APSKAL 683
G+ S P + KG A++ P P P S S P P+ +
Sbjct: 223 GTGGVLS--GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV 280
Query: 684 SG------PEPAK-DNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRK 736
G P PA +V P AL PL + P G +
Sbjct: 281 GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG 340
Query: 737 DRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKK 796
P P + L P P SL PP S PP
Sbjct: 341 GLPPGPEKGPTL------APSPHSL--------------PPASSSA------PAPPMRFP 374
Query: 797 HSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPS 856
+SS SS ++S + A ++ + +S S S++ T+PS PS
Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434
Query: 857 SQSSKKEMLPPPPV------SSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDS 910
+ PPPP S++ P P+ T Q ST +H
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPS---------TGAQSTAHPPVSTHHHHHQQ 485
Query: 911 SIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP 955
+Q++ + + + H S FP P L G+S P
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHP 529
Score = 32.7 bits (73), Expect = 2.1
Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 26/192 (13%)
Query: 772 RIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKK-RKGEAERDCDNKKIRLE 830
R + PG R + + P G SS ++ S + AKK R EA NK+ R E
Sbjct: 16 RKKEAPGPREELR-SRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSE 74
Query: 831 KEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD 890
+ +S+S +++ K ++ + RP S S + R D
Sbjct: 75 EISESESEETNAPKKTKTEQELPRPQSPSDLDSL-------------------DGRSLND 115
Query: 891 TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP--FPVPSLPNG 948
DP +S SI VE SS +G + P FP PS
Sbjct: 116 DGSSDPRDIDQDNRST--SPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFP-PSPQPP 172
Query: 949 NSKPGKPQVKFD 960
+S P +P+ F+
Sbjct: 173 DSTPRQPEASFE 184
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 72.4 bits (176), Expect = 2e-12
Identities = 200/970 (20%), Positives = 303/970 (31%), Gaps = 189/970 (19%)
Query: 46 KTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPL---------IP 96
K A+ +E S+ N G EE+ E S +++ + +E L +P+ P +
Sbjct: 55 KKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLN 114
Query: 97 DKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPK-MAQPRTEPM--PSLHAKSCGP 153
D GSS P ++S P SV N S + ++Q P P L S P
Sbjct: 115 DDGSSDPRD---IDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQP 171
Query: 154 PDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSP 213
PDS + +S G H ++ + P P P P L P
Sbjct: 172 PDSTPRQPE--------ASFEPHPSVTPTGYHAPMEPPTSRMFQAPP--GAPPPHPQLYP 221
Query: 214 -----IHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDL-------AVKVHDKETPQD 261
+ S P+ G++ G N K + P +P + A TP
Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVG 281
Query: 262 SLVAPAQPPSQTFP--------PPSLPSKSVAMQQKPTAYVRP--------------MDG 299
P+ PP FP PP+L + A P +P M G
Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
Query: 300 QDQAPSESPELKPLPEDY--RQQTFEKTDLKVP-AKAKLTKLKMPSQSVEQTYSNEVHCV 356
P + P L P P + ++ P + + + S S + S
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 357 EEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQ 416
+ L HS+PPP T++ + +P K+ P+ SQ V S +SN+
Sbjct: 402 SQALPSYPHSFPPP-TSLSVSN--QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
G PPS+ A +A PV++ H + +
Sbjct: 459 PGPF-----------------------PPSTGAQSTAHP----PVSTHHHHHQQQQQQQQ 491
Query: 477 SDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTE 536
+ + +S P PP L+ + + P A S
Sbjct: 492 QQQQQQQQQQQHHGNSG-----------PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 537 PPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEP-- 594
P P S S + PP SSS + + + +P Q P
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 595 -PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
P TV T + A S + PG PYG R + G +
Sbjct: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR---------APSPGAYKT 651
Query: 654 AASNEPKPAVPPS----SEKKKHKSSLPA------PSKALSGPEPAKDNVEDRTPEHFAL 703
A KP PPS + +S PA P GP P P
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS-LPP 710
Query: 704 VPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMV 763
P + GPP S + + E+ P+P P R PP ++
Sbjct: 711 PPAAPASGPPLSATQIKQEPA-------EEYETPESPVP--------PARSPSPPPKVV- 754
Query: 764 KITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSD-----SSSKLAKKRKGEA 818
+P + +R K D+ +S RS SKLAKKR
Sbjct: 755 --------DVPSHASQSARFNKHLDRG------FNSCARSDLYFVPLEGSKLAKKRADLV 800
Query: 819 ERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSK-----KEMLPPPPVSSS 873
E K+R E E +++ +E K + + + +E P S
Sbjct: 801 E------KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSL 854
Query: 874 SQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSS 933
P +P + P SA +T + P R + S + H S
Sbjct: 855 GPVPHRPPFE-------------PGSAVATVPPYLGPDTPALRTL----SEYARPHVMSP 897
Query: 934 GDTANPFPVP 943
G+ +PF VP
Sbjct: 898 GNRNHPFYVP 907
Score = 60.1 bits (144), Expect = 1e-08
Identities = 127/617 (20%), Positives = 197/617 (31%), Gaps = 70/617 (11%)
Query: 368 PPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427
P P + + A P + D + S +K + T ++QG S
Sbjct: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSE------ 74
Query: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
++S+SE S+ P+K + Q LP P + + S + S +D SS + +
Sbjct: 75 EISESE-SEETNAPKKTKTE-------QELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQ 126
Query: 488 SSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGS 547
D+ P E + + L + P PP P S +PP P +
Sbjct: 127 ---DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP--PPLFPPSPQPPDSTPRQPEA 181
Query: 548 S----DSATSQEHSESKDPPPKSSSKAPR-APPEAP--HPGKRSCQKSPAQQEPPQRQTV 600
S S T + +PP +AP APP P +PG S P
Sbjct: 182 SFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241
Query: 601 -------GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA 653
G KQ P + + S S +P P G + S P P
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPA----NFPHV 297
Query: 654 AASNEPKPAV---------PPSSEKKKHKSSLPAP---SKALSGPEPAKDNVEDRTPEHF 701
+ P PA+ PP + LP+P + + G P + P
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 702 ALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLL-SPLRDTPPPQS 760
+L P + S P +S A S P ++ L S PPP S
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 761 LMV-----KITLDLL------SRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSK 809
L V K T L S+ P PP R + P G S S +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP--GPFPPSTGAQSTAHPP 475
Query: 810 LAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
++ ++ ++ + +++ + Q +S + P S P
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535
Query: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEH 929
+ S P PA + Q P + S++ SS +GS S
Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST-------SQGSYPCSHP 588
Query: 930 KGSSGDTANPFPVPSLP 946
S G P+P P +P
Sbjct: 589 SPSQGPQGAPYPFPPVP 605
Score = 55.1 bits (131), Expect = 4e-07
Identities = 117/525 (22%), Positives = 168/525 (32%), Gaps = 80/525 (15%)
Query: 463 SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTK- 521
+A + E ST + SE S S E N P +T + P + LD+ +
Sbjct: 53 TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRS 112
Query: 522 -----VSQPAAPPEGPRSTEPPRRHP---ESKGSSDSATSQEHSESKDPPPKSSSKAPRA 573
S P + RST P P E+ S S SQ + PPP
Sbjct: 113 LNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF------- 165
Query: 574 PPEAPHPGKRSCQKSPAQQEP-PQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY 632
P +P P + ++ A EP P G P +P ++R P L P
Sbjct: 166 -PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP--PTSRMFQAPPGAPPPHPQLYPG 222
Query: 633 GSRDQTSKDKPKVKTKGRPRAAASNEPK------PAVPPSSEKKKHKSSLP---APSKAL 683
G+ S P + KG A++ P P P S S P P+ +
Sbjct: 223 GTGGVLS--GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV 280
Query: 684 SG------PEPAK-DNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRK 736
G P PA +V P AL PL + P G +
Sbjct: 281 GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG 340
Query: 737 DRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKK 796
P P + L P P SL PP S PP
Sbjct: 341 GLPPGPEKGPTL------APSPHSL--------------PPASSSA------PAPPMRFP 374
Query: 797 HSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPS 856
+SS SS ++S + A ++ + +S S S++ T+PS PS
Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434
Query: 857 SQSSKKEMLPPPPV------SSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDS 910
+ PPPP S++ P P+ T Q ST +H
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPS---------TGAQSTAHPPVSTHHHHHQQ 485
Query: 911 SIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP 955
+Q++ + + + H S FP P L G+S P
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHP 529
Score = 32.7 bits (73), Expect = 2.1
Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 26/192 (13%)
Query: 772 RIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKK-RKGEAERDCDNKKIRLE 830
R + PG R + + P G SS ++ S + AKK R EA NK+ R E
Sbjct: 16 RKKEAPGPREELR-SRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSE 74
Query: 831 KEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD 890
+ +S+S +++ K ++ + RP S S + R D
Sbjct: 75 EISESESEETNAPKKTKTEQELPRPQSPSDLDSL-------------------DGRSLND 115
Query: 891 TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP--FPVPSLPNG 948
DP +S SI VE SS +G + P FP PS
Sbjct: 116 DGSSDPRDIDQDNRST--SPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFP-PSPQPP 172
Query: 949 NSKPGKPQVKFD 960
+S P +P+ F+
Sbjct: 173 DSTPRQPEASFE 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.121 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,056,423
Number of Sequences: 37866
Number of extensions: 3524019
Number of successful extensions: 47868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 569
Number of HSP's successfully gapped in prelim test: 2385
Number of HSP's that attempted gapping in prelim test: 20609
Number of HSP's gapped (non-prelim): 18102
length of query: 1210
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1096
effective length of database: 13,930,794
effective search space: 15268150224
effective search space used: 15268150224
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.