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Search of human proteins with 5174545
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
(521 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 1055 0.0
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] 496 e-140
gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens] 483 e-136
gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens] 442 e-124
gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens] 411 e-115
gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens] 341 1e-93
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] 335 5e-92
gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens] 181 1e-45
gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens] 180 3e-45
gi|239747524 PREDICTED: similar to serum response factor-related... 172 9e-43
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 70 5e-12
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 65 2e-10
gi|19924099 synapsin I isoform Ia [Homo sapiens] 63 7e-10
gi|19924097 synapsin I isoform Ib [Homo sapiens] 63 7e-10
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 61 2e-09
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 61 2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 6e-09
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 60 6e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 60 6e-09
gi|4507205 serum response factor (c-fos serum response element-b... 59 8e-09
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 59 8e-09
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 59 8e-09
gi|55750053 atrophin-1 [Homo sapiens] 58 2e-08
gi|55750041 atrophin-1 [Homo sapiens] 58 2e-08
gi|93277088 mediator of RNA polymerase II transcription, subunit... 56 7e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 56 9e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 56 9e-08
>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
Length = 521
Score = 1055 bits (2728), Expect = 0.0
Identities = 521/521 (100%), Positives = 521/521 (100%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST
Sbjct: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA
Sbjct: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS
Sbjct: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
Query: 181 PQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANG 240
PQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANG
Sbjct: 181 PQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANG 240
Query: 241 NSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGV 300
NSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGV
Sbjct: 241 NSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGV 300
Query: 301 SQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGN 360
SQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGN
Sbjct: 301 SQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGN 360
Query: 361 VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP
Sbjct: 361 VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET 480
LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET
Sbjct: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET 480
Query: 481 GDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK 521
GDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
Sbjct: 481 GDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK 521
>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
Length = 497
Score = 496 bits (1277), Expect = e-140
Identities = 291/547 (53%), Positives = 347/547 (63%), Gaps = 81/547 (14%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN SNKLFQYAST
Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
DMDKVLLKYTEYNEPHESRTN+DI+ETLRKKG NGC+SP D +D E SPL ED++ +
Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESP--DADDYFEHSPLSEDRFSKL 118
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLL 179
+E+ D +F+R +P NF+M VTVPV++ ++L ++NP SLV+PSL SS LTD +L
Sbjct: 119 NEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML 178
Query: 180 SPQQPALQRNSVSPGLPQRPAS---AGAMLGG-DLNSANGACPSPVGNGYVSARASPGLL 235
SP Q L RN VSPG PQRP S AG ML DL NGA SPVGNG+V++RASP L+
Sbjct: 179 SPPQTTLHRN-VSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLI 237
Query: 236 PVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNA 295
NSL KV+P KSPPPP LG SRKPDLRV+ + KG+M L N
Sbjct: 238 GATGANSLGKVMPTKSPPPPGGGN-LGMNSRKPDLRVVIPPSSKGMMPPL--------NT 288
Query: 296 QRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGG 355
QR+ SQ+T L TPVVSV TPSL QGL +S+MPTAYNTDY LTSA+LS+L F+SPG
Sbjct: 289 QRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGM 348
Query: 356 LSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNL 415
LSLG V+AWQQ HL +LS+L
Sbjct: 349 LSLGQVSAWQQ--------------------------------------HHLGQAALSSL 370
Query: 416 IPGSPLPHVGAALTVTTHPHISIKSEPVSPSRER----------------SPAPPPPAVF 459
+ G L G+ L++ T+ +ISIKSEP+SP R+R P PPP
Sbjct: 371 VAGGQLSQ-GSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQP 429
Query: 460 PAARPEPG--------DGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVK 511
+P+P D LSS + SY+ DR+D RGDF + L RP + E +VK
Sbjct: 430 QPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVK 488
Query: 512 RMRLDTW 518
RMR+D W
Sbjct: 489 RMRMDAW 495
>gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]
Length = 499
Score = 483 bits (1243), Expect = e-136
Identities = 287/549 (52%), Positives = 342/549 (62%), Gaps = 83/549 (15%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN SNKLFQYAST
Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
DMDKVLLKYTEYNEPHESRTN+DI+E L KK GCDSP+PD S +P E+KY++
Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPD--TSYVLTPHTEEKYKKI 118
Query: 121 SEELDGLFRRY--GSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPR 177
+EE D + R + +P NF+M VTVPV++ ++L ++NP SLV+PSL SS LTD
Sbjct: 119 NEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSS 178
Query: 178 LLSPQQPALQRNSVSPGLPQRPAS---AGAMLGG-DLNSANGACPSPVGNGYVSARASPG 233
+LSP Q L RN VSPG PQRP S AG ML DL NGA SPVGNG+V++RASP
Sbjct: 179 MLSPPQTTLHRN-VSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPN 237
Query: 234 LLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLN 293
L+ NSL KV+P KSPPPP LG SRKPDLRV+ + KG+M L
Sbjct: 238 LIGATGANSLGKVMPTKSPPPPGGGN-LGMNSRKPDLRVVIPPSSKGMMPPL-------- 288
Query: 294 NAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSP 353
N QR+ SQ+T L TPVVSV TPSL QGL +S+MPTAYNTDY LTSA+LS+L F+SP
Sbjct: 289 NTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSP 348
Query: 354 GGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLS 413
G LSLG V+AWQQ HL +LS
Sbjct: 349 GMLSLGQVSAWQQ--------------------------------------HHLGQAALS 370
Query: 414 NLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRER----------------SPAPPPPA 457
+L+ G L G+ L++ T+ +ISIKSEP+SP R+R P PPP
Sbjct: 371 SLVAGGQLSQ-GSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQP 429
Query: 458 VFPAARPEPG--------DGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSA 509
+P+P D LSS + SY+ DR+D RGDF + L RP + E +
Sbjct: 430 QPQPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPS 488
Query: 510 VKRMRLDTW 518
VKRMR+D W
Sbjct: 489 VKRMRMDAW 497
>gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]
Length = 473
Score = 442 bits (1136), Expect = e-124
Identities = 269/525 (51%), Positives = 330/525 (62%), Gaps = 68/525 (12%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +NKLFQYAST
Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
DMDKVLLKYTEYNEPHESRTN+DI+ETLRKKG NGCDSP+PD +DS+ SP EDKYR+
Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKI 120
Query: 121 SEELDGLFRRYG-STVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLL 179
+E++D + R VP PNF MPV++PVS+ +SL +SNP SSL +P LL
Sbjct: 121 NEDIDLMISRQRLCAVPPPNFEMPVSIPVSSHNSLVYSNP----------VSSLGNPNLL 170
Query: 180 SPQQPALQRNSVSPGLPQRPASA---GAMLGGDLNSANGACPSPVGNGYVSARASPGLLP 236
P+LQRNS+SPG+ RP SA G ++GGDL S G + GNGY + R SPGLL
Sbjct: 171 PLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAG---TSAGNGYGNPRNSPGLL- 226
Query: 237 VANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQ 296
V+ GN LNK + AKSPPP LG +RKPDLRV+ K M ++ED +DL Q
Sbjct: 227 VSPGN-LNKNMQAKSPPP----MNLGMNNRKPDLRVLIPPGSKNTMPSVSED-VDLLLNQ 280
Query: 297 RLGVSQSTHSLTTPVVSVATPSLLSQGLPF--SSMPTAYNTDYQLTSAELSSLPAFSSPG 354
R+ SQS SL TPVVSVATP+L QG+ S++ T Y T+Y L+SA+LSSL F++
Sbjct: 281 RINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTAS 340
Query: 355 GLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSN 414
L LG+VT WQ QQ H +P S +
Sbjct: 341 ALHLGSVTGWQ------------------------------------QQHLHNMPPSALS 364
Query: 415 LIPGSPLPHVGAA--LTVTTHPHISIKSEPVSPSRERSPAPP--PPAVFPAARPEPGDGL 470
+ H+ + L++ + ++IKSEPVSP R+R+ P P A P D L
Sbjct: 365 QLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSL 424
Query: 471 SSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRL 515
SS SY+ DR+D R +F +GL RP+P+ E E +VKRMRL
Sbjct: 425 SS-CSSSYDGSDREDHRNEFHSPIGLTRPSPD-ERESPSVKRMRL 467
>gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]
Length = 463
Score = 411 bits (1057), Expect = e-115
Identities = 256/525 (48%), Positives = 318/525 (60%), Gaps = 78/525 (14%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +NKLFQYAST
Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
DMDKVLLKYTEYNEPHESRTN+DI+E L KK GC+SP+PD +L +P E+KY++
Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGCESPDPDSSYAL--TPRTEEKYKKI 118
Query: 121 SEELDGLFRRYG-STVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLL 179
+EE D + + + VP PNF MPV++PVS+ +SL +SNP SSL +P LL
Sbjct: 119 NEEFDNMIKSHKIPAVPPPNFEMPVSIPVSSHNSLVYSNP----------VSSLGNPNLL 168
Query: 180 SPQQPALQRNSVSPGLPQRPASA---GAMLGGDLNSANGACPSPVGNGYVSARASPGLLP 236
P+LQRNS+SPG+ RP SA G ++GGDL S G + GNGY + R SPGLL
Sbjct: 169 PLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAG---TSAGNGYGNPRNSPGLL- 224
Query: 237 VANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQ 296
V+ GN LNK + AKSPPP LG +RKPDLRV+ K M + Q
Sbjct: 225 VSPGN-LNKNMQAKSPPP----MNLGMNNRKPDLRVLIPPGSKNTMPSVN---------Q 270
Query: 297 RLGVSQSTHSLTTPVVSVATPSLLSQGLPF--SSMPTAYNTDYQLTSAELSSLPAFSSPG 354
R+ SQS SL TPVVSVATP+L QG+ S++ T Y T+Y L+SA+LSSL F++
Sbjct: 271 RINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTAS 330
Query: 355 GLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSN 414
L LG+VT WQ QQ H +P S +
Sbjct: 331 ALHLGSVTGWQ------------------------------------QQHLHNMPPSALS 354
Query: 415 LIPGSPLPHVGAA--LTVTTHPHISIKSEPVSPSRERSPAPP--PPAVFPAARPEPGDGL 470
+ H+ + L++ + ++IKSEPVSP R+R+ P P A P D L
Sbjct: 355 QLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSL 414
Query: 471 SSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRL 515
SS SY+ DR+D R +F +GL RP+P+ E E +VKRMRL
Sbjct: 415 SS-CSSSYDGSDREDHRNEFHSPIGLTRPSPD-ERESPSVKRMRL 457
>gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]
Length = 437
Score = 341 bits (874), Expect = 1e-93
Identities = 211/462 (45%), Positives = 268/462 (58%), Gaps = 73/462 (15%)
Query: 86 ETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPVT 145
+TLRKKG NGC+SP D +D E SPL ED++ + +E+ D +F+R +P NF+M VT
Sbjct: 18 QTLRKKGLNGCESP--DADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVT 75
Query: 146 VPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQPALQRNSVSPGLPQRPAS--- 201
VPV++ ++L ++NP SLV+PSL SS LTD +LSP Q L RN VSPG PQRP S
Sbjct: 76 VPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRN-VSPGAPQRPPSTGN 134
Query: 202 AGAMLGG-DLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQ 260
AG ML DL NGA SPVGNG+V++RASP L+ NSL KV+P KSPPPP
Sbjct: 135 AGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGN- 193
Query: 261 LGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLL 320
LG SRKPDLRV+ + KG+M L+E+ N QR+ SQ+T L TPVVSV TPSL
Sbjct: 194 LGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLP 253
Query: 321 SQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQ 380
QGL +S+MPTAYNTDY LTSA+LS+L F+SPG LSLG V+AWQQ
Sbjct: 254 PQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQ-------------- 299
Query: 381 QQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKS 440
HL +LS+L+ G L G+ L++ T+ +ISIKS
Sbjct: 300 ------------------------HHLGQAALSSLVAGGQLSQ-GSNLSINTNQNISIKS 334
Query: 441 EPVSPSRER----------------SPAPPPPAVFPAARPEPG--------DGLSSPAGG 476
EP+SP R+R P PPP +P+P D LSS +
Sbjct: 335 EPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSS-SSS 393
Query: 477 SYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTW 518
SY+ DR+D RGDF + L RP + E +VKRMR+D W
Sbjct: 394 SYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAW 435
Score = 206 bits (523), Expect = 5e-53
Identities = 173/460 (37%), Positives = 213/460 (46%), Gaps = 116/460 (25%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQ T RK GL CE S
Sbjct: 1 MGRKKIQITRIMDERNRQ---TLRKKGLN----------GCE----------------SP 31
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
D D +++ +E S+ N D + + K+G G P P+
Sbjct: 32 DADD-YFEHSPLSEDRFSKLNED-SDFIFKRGPPGL---PPQNFSMSVTVPVTSPNALS- 85
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
+ GS++ +P+ A T+ S S+++P T R +S
Sbjct: 86 -------YTNPGSSLVSPSLAASSTLTDS------------SMLSPPQTTLH----RNVS 122
Query: 181 PQQPALQRNSVSPGLPQRPASAGAMLG-GDLNSANGACPSPVGNGYVSARASPGLLPVAN 239
P P QR P +AG ML DL NGA SPVGNG+V++RASP L+
Sbjct: 123 PGAP--QR-------PPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATG 173
Query: 240 GNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLG 299
NSL KV+P KSPPPP LG SRKPDLRV+ + KG+M L+E+ N QR+
Sbjct: 174 ANSLGKVMPTKSPPPP-GGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRIS 232
Query: 300 VSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLG 359
SQ+T L TPVVSV TPSL QGL +S+MPTAYNTDY LTSA+LS+L F+SPG LSLG
Sbjct: 233 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG 292
Query: 360 NVTAWQQPQQPQ---------------------------------------------QPQ 374
V+AWQQ Q Q Q
Sbjct: 293 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ 352
Query: 375 QPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSN 414
Q Q QQQPP P QPQPQ PQ QP Q+ SLS+
Sbjct: 353 QQQQQQQQPPPPPQPQPQPPQ--PQPRQEMGRSPVDSLSS 390
>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
Length = 429
Score = 335 bits (860), Expect = 5e-92
Identities = 210/462 (45%), Positives = 265/462 (57%), Gaps = 81/462 (17%)
Query: 86 ETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPVT 145
+TLRKKG NGC+SP D +D E SPL ED++ + +E+ D +F+R +P NF+M VT
Sbjct: 18 QTLRKKGLNGCESP--DADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVT 75
Query: 146 VPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQPALQRNSVSPGLPQRPAS--- 201
VPV++ ++L ++NP SLV+PSL SS LTD +LSP Q L RN VSPG PQRP S
Sbjct: 76 VPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRN-VSPGAPQRPPSTGN 134
Query: 202 AGAMLGG-DLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQ 260
AG ML DL NGA SPVGNG+V++RASP L+ NSL KV+P KSPPPP
Sbjct: 135 AGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGN- 193
Query: 261 LGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLL 320
LG SRKPDLRV+ + KG+M L N QR+ SQ+T L TPVVSV TPSL
Sbjct: 194 LGMNSRKPDLRVVIPPSSKGMMPPL--------NTQRISSSQATQPLATPVVSVTTPSLP 245
Query: 321 SQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQ 380
QGL +S+MPTAYNTDY LTSA+LS+L F+SPG LSLG V+AWQQ
Sbjct: 246 PQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQ-------------- 291
Query: 381 QQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKS 440
HL +LS+L+ G L G+ L++ T+ +ISIKS
Sbjct: 292 ------------------------HHLGQAALSSLVAGGQLSQ-GSNLSINTNQNISIKS 326
Query: 441 EPVSPSRER----------------SPAPPPPAVFPAARPEPG--------DGLSSPAGG 476
EP+SP R+R P PPP +P+P D LSS +
Sbjct: 327 EPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSS-SSS 385
Query: 477 SYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTW 518
SY+ DR+D RGDF + L RP + E +VKRMR+D W
Sbjct: 386 SYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAW 427
Score = 200 bits (509), Expect = 2e-51
Identities = 172/460 (37%), Positives = 210/460 (45%), Gaps = 124/460 (26%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI DERNRQ T RK GL CE S
Sbjct: 1 MGRKKIQITRIMDERNRQ---TLRKKGLN----------GCE----------------SP 31
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA 120
D D +++ +E S+ N D + + K+G G P P+
Sbjct: 32 DADD-YFEHSPLSEDRFSKLNED-SDFIFKRGPPGL---PPQNFSMSVTVPVTSPNALS- 85
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
+ GS++ +P+ A T+ S S+++P T R +S
Sbjct: 86 -------YTNPGSSLVSPSLAASSTLTDS------------SMLSPPQTTLH----RNVS 122
Query: 181 PQQPALQRNSVSPGLPQRPASAGAMLG-GDLNSANGACPSPVGNGYVSARASPGLLPVAN 239
P P QR P +AG ML DL NGA SPVGNG+V++RASP L+
Sbjct: 123 PGAP--QR-------PPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATG 173
Query: 240 GNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLG 299
NSL KV+P KSPPPP LG SRKPDLRV+ + KG+M L N QR+
Sbjct: 174 ANSLGKVMPTKSPPPP-GGGNLGMNSRKPDLRVVIPPSSKGMMPPL--------NTQRIS 224
Query: 300 VSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLG 359
SQ+T L TPVVSV TPSL QGL +S+MPTAYNTDY LTSA+LS+L F+SPG LSLG
Sbjct: 225 SSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLG 284
Query: 360 NVTAWQQPQQPQ---------------------------------------------QPQ 374
V+AWQQ Q Q Q
Sbjct: 285 QVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQ 344
Query: 375 QPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSN 414
Q Q QQQPP P QPQPQ PQ QP Q+ SLS+
Sbjct: 345 QQQQQQQQPPPPPQPQPQPPQ--PQPRQEMGRSPVDSLSS 382
>gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens]
Length = 365
Score = 181 bits (459), Expect = 1e-45
Identities = 131/301 (43%), Positives = 161/301 (53%), Gaps = 44/301 (14%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +N+LFQYAST
Sbjct: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRR- 119
DMD+VLLKYTEY+EPHESRTN DI+ETL+++G G D PE + ++ E+ +K+RR
Sbjct: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP---GEKFRRL 116
Query: 120 ASEELDGLFRRYGSTVPAPNFAMPVTV------PVSNQSSLQFSNPSGS----------- 162
A E D R AP P V P + S L + P+ S
Sbjct: 117 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPK 176
Query: 163 ---------LVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPA----SAGAMLGGD 209
L +PS +TS P L P R S PG P ++ ++ G
Sbjct: 177 AGPPGLVHPLFSPSHLTSKTPPPLYL----PTEGRRSDLPGGLAGPRGGLNTSRSLYSGL 232
Query: 210 LNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPP--PPTHSTQLGAPSRK 267
N + A P P + PG PV +V +PP PP ++ L A R
Sbjct: 233 QNPCSTATPGPPLGSFPFL---PGGPPVGAEAWARRVPQPAAPPRRPPQSASSLSASLRP 289
Query: 268 P 268
P
Sbjct: 290 P 290
>gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens]
Length = 368
Score = 180 bits (456), Expect = 3e-45
Identities = 171/468 (36%), Positives = 204/468 (43%), Gaps = 130/468 (27%)
Query: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60
MGRKKIQI RI D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +N+LFQYAST
Sbjct: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
Query: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRR- 119
DMD+VLLKYTEY+EPHESRTN DI+ETL+++G G D PE + ++ E+ +K+RR
Sbjct: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP---GEKFRRL 116
Query: 120 ASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLL 179
A E D R AP P V G+L P DP L
Sbjct: 117 AGEGGDPALPRPRLYPAAPAMPSPDVV-------------YGALPPPG------CDPSGL 157
Query: 180 SPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLL-PVA 238
PA R S P RPA+ A PGL+ P+
Sbjct: 158 GEALPAQSRPS-----PFRPAAPKA-------------------------GPPGLVHPLF 187
Query: 239 NGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRL 298
+ + L +K+PPP L R+ DL + G L
Sbjct: 188 SPSHLT----SKTPPP----LYLPTEGRRSDLPGGLAGPRGG-----------------L 222
Query: 299 GVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSL 358
S+S +S S ATP G P S P PGG
Sbjct: 223 NTSRSLYSGLQNPCSTATP-----GPPLGSFPFL--------------------PGG--- 254
Query: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPG 418
P+ PP QP P QP + PP S P +L
Sbjct: 255 ----------PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ--PSGGRSLGEE 302
Query: 419 SPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEP 466
P P GA+ P +SIKSE + SPAP P FP P P
Sbjct: 303 GP-PTRGAS---PPTPPVSIKSERL------SPAPGGPGDFPKTFPYP 340
>gi|239747524 PREDICTED: similar to serum response factor-related
protein C4 [Homo sapiens]
Length = 434
Score = 172 bits (435), Expect = 9e-43
Identities = 103/207 (49%), Positives = 129/207 (62%), Gaps = 11/207 (5%)
Query: 82 ADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGST--VPAPN 139
A I+E L KK GCDS +PD S +P E+KY++ +EE D + + + +P N
Sbjct: 200 AYIVEALNKKEHRGCDSSDPD--TSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQN 257
Query: 140 FAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQPALQRNSVSPGLPQR 198
F+M VTVPV + ++L ++NP SLV+PSL SS LTD LSP Q L RN VSPG PQR
Sbjct: 258 FSMSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRN-VSPGAPQR 316
Query: 199 PAS---AGAMLGG-DLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPP 254
P S AG MLG DL NG SPVGN +V++RASP L+ NSL KV+P KSPPP
Sbjct: 317 PPSTGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPP 376
Query: 255 PTHSTQLGAPSRKPDLRVITSQAGKGL 281
P S LG S KPDLRV+ + KG+
Sbjct: 377 PGGS-NLGMNSGKPDLRVVIPASSKGM 402
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 70.1 bits (170), Expect = 5e-12
Identities = 58/180 (32%), Positives = 68/180 (37%), Gaps = 39/180 (21%)
Query: 368 QQPQQPQQPQPPQQQPPQ---PQQPQPQQPQQPQQPPQQQSHLV--------------PV 410
QQ QQP QPP QQPP P PQP Q QQP PPQ S V P
Sbjct: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126
Query: 411 SLSNLIPGSP-----LPHVGAALTVTTHPHIS------------IKSEPVSPSRERSPAP 453
+ S+ P +P P G T T P ++ P +P + P P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186
Query: 454 PPPAV-FPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKR 512
PP AV P P+ G G P GG G + G GP L P+P G R
Sbjct: 187 PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGG----GPGLSTPGGHPKPPHRGGGEPR 242
Score = 37.7 bits (86), Expect = 0.026
Identities = 42/160 (26%), Positives = 51/160 (31%), Gaps = 35/160 (21%)
Query: 354 GGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLS 413
GG G + ++ P Q + P P P+P P P QQQ
Sbjct: 21 GGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP------- 73
Query: 414 NLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPP-----PAVFPAARPEPGD 468
P P P HP P +++ P PPP P V P PG
Sbjct: 74 ---PQQPPPQQPPPHQPPPHP---------QPHQQQQPPPPPQDSSKPVVAQGPGPAPGV 121
Query: 469 GLSSPAGGSY-----ETGDRDDGRGDFGPTLGLLRPAPEP 503
G + PA S T G G GPT P P P
Sbjct: 122 GSAPPASSSAPPATPPTSGAPPGSGP-GPT-----PTPPP 155
Score = 30.0 bits (66), Expect = 5.4
Identities = 42/164 (25%), Positives = 54/164 (32%), Gaps = 25/164 (15%)
Query: 99 PEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSN 158
P P + P +D + + G GS PA + A P T P S + S
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS--GAPPGSG 146
Query: 159 PSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAG-------AMLGGDLN 211
P + P VTS+ P P P S G+P P AG A+ G
Sbjct: 147 PGPTPTPPPAVTSA--PPGAPPPTPP-------SSGVPTTPPQAGGPPPPPAAVPGPGPG 197
Query: 212 SANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPP 255
G P G + PG G L+ P P PP
Sbjct: 198 PKQGPGPGGPKGGKMPGGPKPG-----GGPGLS--TPGGHPKPP 234
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 65.1 bits (157), Expect = 2e-10
Identities = 93/351 (26%), Positives = 135/351 (38%), Gaps = 39/351 (11%)
Query: 136 PAPNFAMPVTVPVSNQSSLQFSN---PSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVS 192
PAP A V + +S S+ PS L+ S + P PA+Q + S
Sbjct: 546 PAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGS 605
Query: 193 PGLP----QRPASAGAMLGGD---LNSANGACPSPVGNGYVSARASPGLLPVANGNSLNK 245
GL + P LG + + P+P G ++S G LP A +
Sbjct: 606 TGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGA--- 662
Query: 246 VIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTH 305
+ A SP P L P L ++ G ++ + L + Q+L + H
Sbjct: 663 -VQASSPAPLQFF--LNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAH 719
Query: 306 SLTTPVVSVATPSLLSQGLPFSSM------PTAYNTDYQLTS--AELSSLPAFSSPG-GL 356
P + L +QG F + PT + Q A LS L + P G+
Sbjct: 720 P-PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGV 778
Query: 357 SLGNVTAWQQPQQPQQPQQPQPPQQQP-PQPQQPQPQQPQQPQ---------QPPQQQSH 406
L +V QQPQ PQ P+ PQ QP P+ +QPQ QQ QQPQ + QQ H
Sbjct: 779 QLPSVLRQQQPQ-PQPPKLQLQPQWQPKPRQEQPQSQQ-QQPQHIQLQTQQLRVLQQPQH 836
Query: 407 L-VPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPP 456
+ + ++ GA V HP + + S+ V +E P PP P
Sbjct: 837 IQLQTQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887
Score = 35.4 bits (80), Expect = 0.13
Identities = 78/357 (21%), Positives = 127/357 (35%), Gaps = 49/357 (13%)
Query: 132 GSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSV 191
G++ P P+ P S +++ + + + + ++ P L + PAL +
Sbjct: 477 GNSFPPQQAGSPLKRPFSAAAAIAAA-AAAAAAAAAAAAAAAPAPALAAAAAPALAA-AA 534
Query: 192 SPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKS 251
+P L A A A A P+ +A A+P + + P +
Sbjct: 535 APALAAAAAPA---------PAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPA 585
Query: 252 PPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVS----QSTHSL 307
PPT ++ P +++ T G ++ + AQ LG S Q+ S
Sbjct: 586 AQPPTKFIKIA-----PAIQLRTGSTGLKAINV----EGPVQGAQALGSSFKPVQAPGSG 636
Query: 308 TTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAF-SSPGGLSLGNVTAWQQ 366
++ L S G P +P A Q +S + L F ++P GL +T Q
Sbjct: 637 APAPAGISGSDLQSSGGP---LPDARPGAVQASSP--APLQFFLNTPEGLR--PLTLLQV 689
Query: 367 PQQ------PQQPQQPQPPQQQPPQPQQPQPQQP-----------QQPQQPPQQQSHLVP 409
PQ PQQ QQ QP P QP Q P QQ + P
Sbjct: 690 PQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNP 749
Query: 410 VSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEP 466
+ + P P V + L P ++ V ++ P PP + P +P+P
Sbjct: 750 TRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKP 806
Score = 32.3 bits (72), Expect = 1.1
Identities = 32/145 (22%), Positives = 54/145 (37%), Gaps = 28/145 (19%)
Query: 351 SSPGGLSLGNVTAWQQPQQP-----QQPQQPQPPQQQPPQPQQPQ------------PQQ 393
SS G S+ +++W+ P+QP Q + + PP+ Q P PQQ
Sbjct: 425 SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQ 484
Query: 394 PQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEP-----VSPSRE 448
P + P + + + + + AA P ++ + P +P+
Sbjct: 485 AGSPLKRPFSAAAAIAAAAA-----AAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALA 539
Query: 449 RSPAP-PPPAVFPAARPEPGDGLSS 472
+ AP P PA PA P S+
Sbjct: 540 AAAAPAPAPAAAPAVAAAPAAAASA 564
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 62.8 bits (151), Expect = 7e-10
Identities = 61/182 (33%), Positives = 70/182 (38%), Gaps = 38/182 (20%)
Query: 352 SPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQ---PQQPQQPPQQQSHLV 408
SPG L LG T+ QQP P Q+P PPQ PPQP P PQ+ P Q + PPQ Q H
Sbjct: 438 SPGALPLGRQTS-QQPAGPPAQQRP-PPQGGPPQPG-PGPQRQGPPLQQRPPPQGQQH-- 492
Query: 409 PVSLSNLIP--GSPLPHVGAALTVTTHPHISIKSEPV-SPSRERSPAPPPPAVFPAAR-- 463
LS L P GSPLP + T S + P R+ P P PAAR
Sbjct: 493 ---LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549
Query: 464 ----------------------PEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP 501
P P +P GG G G GPT + P
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGP 609
Query: 502 EP 503
P
Sbjct: 610 VP 611
Score = 37.0 bits (84), Expect = 0.044
Identities = 60/263 (22%), Positives = 80/263 (30%), Gaps = 35/263 (13%)
Query: 222 GNGYVSARASPGLLPVANGNSLNKV-IPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKG 280
G G SPG LP+ S PA+ PPP P + + +
Sbjct: 429 GRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQ 488
Query: 281 LMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGL---------------- 324
HL+ + + T + P S A P QG
Sbjct: 489 GQQHLSGLGPPAGSPLPQRLPSPTSAPQQP-ASQAAPPTQGQGRQSRPVAGGPGAPPAAR 547
Query: 325 -PFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQP------- 376
P S P Q T S PA G G PQ+P P P
Sbjct: 548 PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQA 607
Query: 377 -QPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPH 435
P+ PP QQP+P P +P Q + S +P P AA HP
Sbjct: 608 GPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQ----KPSQDVP----PPATAAAGGPPHPQ 659
Query: 436 ISIKSEPVSPSRERSPAPPPPAV 458
++ + PAPP P++
Sbjct: 660 LNKSQSLTNAFNLPEPAPPRPSL 682
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 62.8 bits (151), Expect = 7e-10
Identities = 61/182 (33%), Positives = 70/182 (38%), Gaps = 38/182 (20%)
Query: 352 SPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQ---PQQPQQPPQQQSHLV 408
SPG L LG T+ QQP P Q+P PPQ PPQP P PQ+ P Q + PPQ Q H
Sbjct: 438 SPGALPLGRQTS-QQPAGPPAQQRP-PPQGGPPQPG-PGPQRQGPPLQQRPPPQGQQH-- 492
Query: 409 PVSLSNLIP--GSPLPHVGAALTVTTHPHISIKSEPV-SPSRERSPAPPPPAVFPAAR-- 463
LS L P GSPLP + T S + P R+ P P PAAR
Sbjct: 493 ---LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549
Query: 464 ----------------------PEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP 501
P P +P GG G G GPT + P
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGP 609
Query: 502 EP 503
P
Sbjct: 610 VP 611
Score = 38.9 bits (89), Expect = 0.012
Identities = 69/270 (25%), Positives = 86/270 (31%), Gaps = 50/270 (18%)
Query: 222 GNGYVSARASPGLLPVANGNSLNKV-IPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKG 280
G G SPG LP+ S PA+ PPP Q G P P + G
Sbjct: 429 GRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPP----QGGPPQPGPG----PQRQGPP 480
Query: 281 LMHH-LTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQL 339
L + L+ S L +P + P+ SQ P PT
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPA--SQAAP----PT-------- 526
Query: 340 TSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQ---------PQPPQQQ--PPQPQQ 388
S P PG A PQ+ P Q P PP+ PP QQ
Sbjct: 527 QGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ 586
Query: 389 PQ--PQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPS 446
Q PQ+P P P +Q S P+P G T P + P
Sbjct: 587 RQGPPQKPPGPAGPTRQASQ-----------AGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635
Query: 447 RERSPAP--PPPAVFPAARPEPGDGLSSPA 474
+ P+ PPPA A P +SPA
Sbjct: 636 LAQKPSQDVPPPATAAAGGPPHPQLKASPA 665
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/80 (45%), Positives = 44/80 (55%), Gaps = 9/80 (11%)
Query: 365 QQPQ----QPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
QQPQ QPQ QP PPQQQP Q QPQPQQP P PPQQQ L S++N +P
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQP-PPPPPPQQQPPLSQCSMNNSFTPAP 1715
Query: 421 ----LPHVGAALTVTTHPHI 436
+P G+ ++ + I
Sbjct: 1716 MIMEIPESGSTGNISIYERI 1735
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 54/160 (33%)
Query: 303 STHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVT 362
S+ S T V T + S G S M Q +S + ++ + SP +
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMM--------QQSSVQPAANCSIKSPQSCVV---- 1640
Query: 363 AWQQPQQPQQPQQPQPPQQQP-PQPQQPQPQ-QPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
++P QQ Q P PP QQP P P QPQP QP PQQ PQQQ
Sbjct: 1641 --ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQ-------------- 1684
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFP 460
P ++ P PPPP P
Sbjct: 1685 ------------------------PQPQQPPPPPPPQQQP 1700
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 2/118 (1%)
Query: 371 QQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
Q+ ++ P++ P P++ + ++ Q + ++ + S + SP + T
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264
Query: 431 TTHPHISIKSEP--VSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDG 486
T P + + E VS + +S P E + ++ D DDG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDG 1322
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/80 (45%), Positives = 44/80 (55%), Gaps = 9/80 (11%)
Query: 365 QQPQ----QPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
QQPQ QPQ QP PPQQQP Q QPQPQQP P PPQQQ L S++N +P
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQP-PPPPPPQQQPPLSQCSMNNSFTPAP 1715
Query: 421 ----LPHVGAALTVTTHPHI 436
+P G+ ++ + I
Sbjct: 1716 MIMEIPESGSTGNISIYERI 1735
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 54/160 (33%)
Query: 303 STHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVT 362
S+ S T V T + S G S M Q +S + ++ + SP +
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMM--------QQSSVQPAANCSIKSPQSCVV---- 1640
Query: 363 AWQQPQQPQQPQQPQPPQQQP-PQPQQPQPQ-QPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
++P QQ Q P PP QQP P P QPQP QP PQQ PQQQ
Sbjct: 1641 --ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQ-------------- 1684
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFP 460
P ++ P PPPP P
Sbjct: 1685 ------------------------PQPQQPPPPPPPQQQP 1700
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 2/118 (1%)
Query: 371 QQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
Q+ ++ P++ P P++ + ++ Q + ++ + S + SP + T
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264
Query: 431 TTHPHISIKSEP--VSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDG 486
T P + + E VS + +S P E + ++ D DDG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDG 1322
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/80 (45%), Positives = 44/80 (55%), Gaps = 9/80 (11%)
Query: 365 QQPQ----QPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
QQPQ QPQ QP PPQQQP Q QPQPQQP P PPQQQ L S++N +P
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQP-PPPPPPQQQPPLSQCSMNNSFTPAP 1715
Query: 421 ----LPHVGAALTVTTHPHI 436
+P G+ ++ + I
Sbjct: 1716 MIMEIPESGSTGNISIYERI 1735
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 54/160 (33%)
Query: 303 STHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVT 362
S+ S T V T + S G S M Q +S + ++ + SP +
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMM--------QQSSVQPAANCSIKSPQSCVV---- 1640
Query: 363 AWQQPQQPQQPQQPQPPQQQP-PQPQQPQPQ-QPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
++P QQ Q P PP QQP P P QPQP QP PQQ PQQQ
Sbjct: 1641 --ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQ-------------- 1684
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFP 460
P ++ P PPPP P
Sbjct: 1685 ------------------------PQPQQPPPPPPPQQQP 1700
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/118 (17%), Positives = 44/118 (37%), Gaps = 2/118 (1%)
Query: 371 QQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
Q+ ++ P++ P P++ + ++ Q + ++ + S + SP + T
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264
Query: 431 TTHPHISIKSEP--VSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDG 486
T P + + E VS + +S P E + ++ D DDG
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDG 1322
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 61.2 bits (147), Expect = 2e-09
Identities = 47/111 (42%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 366 QPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVG 425
Q QQ QQ QQ Q QQQ Q QQPQ QQP QPQ QQQ LV + P P P +
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQ-QQPPQPQTQQQQQPALVNYNR----PSGPGPELS 270
Query: 426 AALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGG 476
P K +P SPAPP A PAA PG + PA G
Sbjct: 271 G-------PSTPQKLPVPAPGGRPSPAPPAAAQPPAA-AVPGPSVPQPAPG 313
Score = 33.9 bits (76), Expect = 0.37
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 350 FSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVP 409
+ SP LG A + P P PPQ P QP P PQ QP + S P
Sbjct: 120 YMSPHPSPLG---APEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSP 176
Query: 410 VSLSNL 415
V L L
Sbjct: 177 VQLHQL 182
Score = 33.5 bits (75), Expect = 0.48
Identities = 68/289 (23%), Positives = 92/289 (31%), Gaps = 53/289 (18%)
Query: 126 GLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPA 185
G + G P P P + P+ S S L P V+S ++ PQ P
Sbjct: 92 GSMKGTGMRPPHPGMGPPQS-PMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPP 150
Query: 186 LQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNK 245
Q ++ PG PQ AM S PSP SP L L
Sbjct: 151 SQPGALIPGDPQ------AM------SQPNRGPSPF---------SPVQLHQLRAQILAY 189
Query: 246 VIPAKSPPPPTHSTQLGAPSRK--PDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQS 303
+ A+ P P + QL ++ P L+ Q + + Q+ Q+
Sbjct: 190 KMLARGQPLP-ETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQT 248
Query: 304 THSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTA 363
+V+ PS L S P LP +PGG
Sbjct: 249 QQQQQPALVNYNRPSGPGPELSGPSTP--------------QKLPV-PAPGGRP------ 287
Query: 364 WQQPQQPQQPQQPQPPQQQPPQPQ--QPQPQQPQQPQQPPQQQSHLVPV 410
P P QPP P P QP P QP Q Q+QS + P+
Sbjct: 288 -----SPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPI 331
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 61.2 bits (147), Expect = 2e-09
Identities = 47/111 (42%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 366 QPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVG 425
Q QQ QQ QQ Q QQQ Q QQPQ QQP QPQ QQQ LV + P P P +
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQ-QQPPQPQTQQQQQPALVNYNR----PSGPGPELS 270
Query: 426 AALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGG 476
P K +P SPAPP A PAA PG + PA G
Sbjct: 271 G-------PSTPQKLPVPAPGGRPSPAPPAAAQPPAA-AVPGPSVPQPAPG 313
Score = 33.9 bits (76), Expect = 0.37
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 350 FSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVP 409
+ SP LG A + P P PPQ P QP P PQ QP + S P
Sbjct: 120 YMSPHPSPLG---APEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSP 176
Query: 410 VSLSNL 415
V L L
Sbjct: 177 VQLHQL 182
Score = 33.5 bits (75), Expect = 0.48
Identities = 68/289 (23%), Positives = 92/289 (31%), Gaps = 53/289 (18%)
Query: 126 GLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPA 185
G + G P P P + P+ S S L P V+S ++ PQ P
Sbjct: 92 GSMKGTGMRPPHPGMGPPQS-PMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPP 150
Query: 186 LQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNK 245
Q ++ PG PQ AM S PSP SP L L
Sbjct: 151 SQPGALIPGDPQ------AM------SQPNRGPSPF---------SPVQLHQLRAQILAY 189
Query: 246 VIPAKSPPPPTHSTQLGAPSRK--PDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQS 303
+ A+ P P + QL ++ P L+ Q + + Q+ Q+
Sbjct: 190 KMLARGQPLP-ETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQT 248
Query: 304 THSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTA 363
+V+ PS L S P LP +PGG
Sbjct: 249 QQQQQPALVNYNRPSGPGPELSGPSTP--------------QKLPV-PAPGGRP------ 287
Query: 364 WQQPQQPQQPQQPQPPQQQPPQPQ--QPQPQQPQQPQQPPQQQSHLVPV 410
P P QPP P P QP P QP Q Q+QS + P+
Sbjct: 288 -----SPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPI 331
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 59.7 bits (143), Expect = 6e-09
Identities = 87/337 (25%), Positives = 121/337 (35%), Gaps = 46/337 (13%)
Query: 134 TVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSP 193
T+P+P P P S + + PS + P V SLT P L +P P
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP--------- 406
Query: 194 GLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPP 253
L A LG A + + ++ SP PA +PP
Sbjct: 407 -LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR-------------PASTPP 452
Query: 254 -PPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVV 312
P L P+ P L+ S A L LT ++ Q L S ++HS P+
Sbjct: 453 DSPPLQAPLSLPA-SPPLQTSLSPAVSPLSSPLT-----IHPLQALS-SLASHSPQAPLS 505
Query: 313 SVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQ 372
S+ P L +Q + P+ LT+ L +LP+ + P L +A +
Sbjct: 506 SLIMPPLETQS--SLAPPSLQTPPASLTTPPLENLPSLAPP---PLQTASAPLTTPHLET 560
Query: 373 PQQPQP-PQQQPPQP-QQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
P P P P Q PP P P P+ P PP Q P S + G P P + T
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP---PALASPPLQGLPSPPLSPLAT- 616
Query: 431 TTHPHISIKSEPVSPSRERSPAPP-PPAVFPAARPEP 466
P P + P+PP P + P A P P
Sbjct: 617 ---PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Score = 59.7 bits (143), Expect = 6e-09
Identities = 106/442 (23%), Positives = 137/442 (30%), Gaps = 96/442 (21%)
Query: 97 DSPEPDGEDSLEQSPLLEDKYRRASEELDG-----------LFRRYGSTVPAPNFAMPVT 145
DSP SL SP L+ A L + P + MP
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-- 510
Query: 146 VPVSNQSSL---QFSNPSGSLVTPSL-------------VTSSLTDPRLLSPQQPALQRN 189
P+ QSSL P SL TP L ++ LT P L +P PA
Sbjct: 511 -PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 190 SVSPG-LPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIP 248
P L P + + A A SP G S SP P + P
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629
Query: 249 AKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLT 308
++PP P S L +P P + QA L HL L
Sbjct: 630 LQAPPSPPASPPL-SPLATP-----SPQAPNALAVHL---------------------LQ 662
Query: 309 TPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQP- 367
P +P + + P +S P + S+ P +P L+ + P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSP-----------SATPPSQAPPSLAAPPLQVPPSPP 711
Query: 368 -QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGA 426
P P PPQ PP P P P PP S P + L+ P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP------ 765
Query: 427 ALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDG 486
L V P S+ P+ A PPP PA P L SP G
Sbjct: 766 -LQVPPSPPASLPMSPL--------AKPPPQAPPALATPPLQALPSPPASF-------PG 809
Query: 487 RGDFGPTLGL-LRP--APEPEA 505
+ F P+ L + P P P+A
Sbjct: 810 QAPFSPSASLPMSPLATPPPQA 831
Score = 42.4 bits (98), Expect = 0.001
Identities = 102/410 (24%), Positives = 132/410 (32%), Gaps = 71/410 (17%)
Query: 138 PNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS-----PQQPALQRNSVS 192
P A+P P+ S S P L TPS + LL P P +Q
Sbjct: 623 PXLALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
Query: 193 PGLPQRPASAGAMLGGDLNSANGACPSPVG-NGYVSARASPGLLPVANGNSLNKVIPAKS 251
P P P S A + A P V + S SP P P +
Sbjct: 680 PASP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Query: 252 PPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPV 311
PP P S + +PS P RV A L + + L +S
Sbjct: 738 PPSPPASPPM-SPSATPPPRVPPLLAAPPLQ-------VPPSPPASLPMSPLAKPPPQAP 789
Query: 312 VSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQ 371
++ATP L + P +S P Q + +SLP SP A PQ P
Sbjct: 790 PALATPPLQALPSPPASFPG------QAPFSPSASLPM--SP--------LATPPPQAP- 832
Query: 372 QPQQPQPPQQQPPQPQ-QPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
P P Q PP P P Q P++P P S P L PG P P + +
Sbjct: 833 -PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Query: 431 TTHPHISIKSEPVSPSRER-----------SPAPPPP-----AVFPAA-----------R 463
+ P ++ S + + E + A PPP A PAA R
Sbjct: 892 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 951
Query: 464 PEPGDGLSSPAGGSYETGD------RDDGRGDFGPTLGLLRPAPEPEAEG 507
PG L P + D +G P G L P P P G
Sbjct: 952 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001
Score = 34.7 bits (78), Expect = 0.22
Identities = 87/340 (25%), Positives = 111/340 (32%), Gaps = 98/340 (28%)
Query: 166 PSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGY 225
P SS ++ P A +R S GL QRPAS L+S+ SP +G
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGL-QRPASRS------LSSSATPLSSPARSG- 256
Query: 226 VSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHL 285
SAR +P P K + A PP T + AP+ P
Sbjct: 257 PSARGTPRA-PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----------------- 298
Query: 286 TEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELS 345
S+ L TP +PS G +P N L A L
Sbjct: 299 ----------------LSSSPLATP-----SPS----GTKARPVPPPDNAATPLP-ATLP 332
Query: 346 SLPAFSSPGGLSLGNVTAWQQPQQPQQPQQP-----------QPPQQQPPQPQQPQPQQP 394
P ++P P P P P PP Q PP P Q P
Sbjct: 333 PSPPLATP------------LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 395 QQPQQ-PPQQQSHLVPVSLSNLIPGSPL--------PHVGAALTVTTHPHISI-----KS 440
Q PP Q H + S S P SPL +G+ TH +++ ++
Sbjct: 381 PSLQTIPPIQVPHSL-TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 441 EPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET 480
SPSR PA PP P P LS PA +T
Sbjct: 440 SLTSPSR---PASTPPDSPPLQAP-----LSLPASPPLQT 471
Score = 33.9 bits (76), Expect = 0.37
Identities = 53/230 (23%), Positives = 75/230 (32%), Gaps = 31/230 (13%)
Query: 243 LNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQ 302
L + P+ P PPT + S S A + + S+
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR--------RPSAGGGLQRPASR 240
Query: 303 STHSLTTPVVSVATPSLLSQGLPFS----SMPTAYNTDY----QLTSAELSSLPAFSSPG 354
S S TP+ S A ++G P + S P Q+T + PA G
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL---G 297
Query: 355 GLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQP---------QQPQPQQPQQPQQPPQQQS 405
LS + A P + P P P P P P P P PP Q+
Sbjct: 298 PLS-SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Query: 406 HLVPVSL--SNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAP 453
P + S P P + A ++ T P I + SPS + P+P
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/137 (35%), Positives = 59/137 (43%), Gaps = 22/137 (16%)
Query: 347 LPAFSSPGGLSLGNVTAWQQPQQPQQPQQ-PQPPQQQPPQPQQP-------QPQQPQQPQ 398
+P + G G QQ Q P QQ P P QQQPP QQP QP QQPQ
Sbjct: 451 IPPYGQQGPSGYG-----QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505
Query: 399 -QPPQQQSHLVPVSLSNLIP---GSPLPHVGAALTVTTHPHIS---IKSEPVSPSRERSP 451
QPPQ QS P S P SP P+ T HP + + SP +++ P
Sbjct: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565
Query: 452 APPPPAVF--PAARPEP 466
P P+ AA P+P
Sbjct: 566 QQPAPSTLSQQAAYPQP 582
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/205 (25%), Positives = 74/205 (36%), Gaps = 35/205 (17%)
Query: 325 PFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQP------ 378
P P Y + T S P +S P Q P Q QQPQQP P
Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA---------QSPYQQQQPQQPAPSTLSQQ 576
Query: 379 ---PQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPH 435
PQ Q Q QQ Q + P PPQ+ S S S P + ++ +
Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFP--PPQELS-----QDSFGSQASSAPSMTSSKGGQEDMN 629
Query: 436 ISIKSEPVS-PSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTL 494
+S++S P S P S P A P G+S+ S + + + F P
Sbjct: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSP----GVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 495 -----GLLRPAPEPEAEGSAVKRMR 514
G+ P+P P ++V + R
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSR 710
Score = 38.1 bits (87), Expect = 0.020
Identities = 89/369 (24%), Positives = 119/369 (32%), Gaps = 65/369 (17%)
Query: 125 DGLFRRYGSTVPAPNF--AMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQ 182
D F++ S P P + +M + + S +P GS+ + +DP + S Q
Sbjct: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRK-----APGSDPFMSSGQ 1250
Query: 183 QPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPS-PVGNGYVSARASPGLLPVANGN 241
P + G P A AG LG N A G P G Y R PG+ P N
Sbjct: 1251 GP-----NGGMGDPYSRA-AGPGLG---NVAMGPRQHYPYGGPYDRVRTEPGIGPEGN-- 1299
Query: 242 SLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVS 301
++ P + P + + +PSR P Q+
Sbjct: 1300 -MSTGAPQPNLMPSNPDSGMYSPSRYPP-------------------------QQQQQQQ 1333
Query: 302 QSTHSLTTPVVSVATPSLLSQGLPFSSMPTA-YNTDYQLTSAELSSLPAFSSPGGLSLGN 360
Q S + TPS G PF S T Y Q + + P G
Sbjct: 1334 QRHDSYGNQFSTQGTPS----GSPFPSQQTTMYQQQQQNYKRPMDG--TYGPPAKRHEGE 1387
Query: 361 VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP 420
+ + P Q QP QQQ P P QPQP QQ QP QQ G+
Sbjct: 1388 MYS-----VPYSTGQGQPQQQQLP-PAQPQPASQQQAAQPSPQQDVYNQY-------GNA 1434
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET 480
P A T P R+R APP P+ G + +
Sbjct: 1435 YPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQ 1494
Query: 481 GDRDDGRGD 489
G GR D
Sbjct: 1495 GTMWQGRND 1503
Score = 37.0 bits (84), Expect = 0.044
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
Query: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAA 427
Q P P P PP +PP P Q PP Q+H+ VS +P +
Sbjct: 1552 QPPYGPSAPVPPMTRPP---------PSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPS 1602
Query: 428 LTVTTHPHISI-KSEPVSPSRERSPAPPPP 456
+ H + + K+ P P+ +PAP P
Sbjct: 1603 KSPFLHSGMKMQKAGPPVPASHIAPAPVQP 1632
Score = 30.0 bits (66), Expect = 5.4
Identities = 60/257 (23%), Positives = 80/257 (31%), Gaps = 52/257 (20%)
Query: 262 GAPSRKPDLRVITSQAGK--GLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSL 319
G P +PDL+ AG L ++LTE GV HS + P
Sbjct: 92 GGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS----AAAALPPPA 147
Query: 320 LSQGLPFSSMPTAYNT------DYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQP 373
G P+ P+A Q + L A S GG G + + PQQ
Sbjct: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG---GGLEPYAGPQQNSHD 204
Query: 374 QQ-PQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTT 432
P Q P + PP ++ +LS+ P P GAA +
Sbjct: 205 HGFPN---------HQYNSYYPNRSAYPPPAPAY----ALSS--PRGGTPGSGAAAAAGS 249
Query: 433 HP----HISIKSEPVSPSRERSPA------------PPPPAVFPAAR-----PEPGDGLS 471
P S S S +++R A P P P P G
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 472 SPAGGSYETGDRDDGRG 488
GG Y G +D G G
Sbjct: 310 GYPGGDYSGGPQDGGAG 326
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/137 (35%), Positives = 59/137 (43%), Gaps = 22/137 (16%)
Query: 347 LPAFSSPGGLSLGNVTAWQQPQQPQQPQQ-PQPPQQQPPQPQQP-------QPQQPQQPQ 398
+P + G G QQ Q P QQ P P QQQPP QQP QP QQPQ
Sbjct: 451 IPPYGQQGPSGYG-----QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505
Query: 399 -QPPQQQSHLVPVSLSNLIP---GSPLPHVGAALTVTTHPHIS---IKSEPVSPSRERSP 451
QPPQ QS P S P SP P+ T HP + + SP +++ P
Sbjct: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565
Query: 452 APPPPAVF--PAARPEP 466
P P+ AA P+P
Sbjct: 566 QQPAPSTLSQQAAYPQP 582
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/205 (25%), Positives = 74/205 (36%), Gaps = 35/205 (17%)
Query: 325 PFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQP------ 378
P P Y + T S P +S P Q P Q QQPQQP P
Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA---------QSPYQQQQPQQPAPSTLSQQ 576
Query: 379 ---PQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPH 435
PQ Q Q QQ Q + P PPQ+ S S S P + ++ +
Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFP--PPQELS-----QDSFGSQASSAPSMTSSKGGQEDMN 629
Query: 436 ISIKSEPVS-PSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTL 494
+S++S P S P S P A P G+S+ S + + + F P
Sbjct: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSP----GVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 495 -----GLLRPAPEPEAEGSAVKRMR 514
G+ P+P P ++V + R
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSR 710
Score = 30.0 bits (66), Expect = 5.4
Identities = 60/257 (23%), Positives = 80/257 (31%), Gaps = 52/257 (20%)
Query: 262 GAPSRKPDLRVITSQAGK--GLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSL 319
G P +PDL+ AG L ++LTE GV HS + P
Sbjct: 92 GGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS----AAAALPPPA 147
Query: 320 LSQGLPFSSMPTAYNT------DYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQP 373
G P+ P+A Q + L A S GG G + + PQQ
Sbjct: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG---GGLEPYAGPQQNSHD 204
Query: 374 QQ-PQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTT 432
P Q P + PP ++ +LS+ P P GAA +
Sbjct: 205 HGFPN---------HQYNSYYPNRSAYPPPAPAY----ALSS--PRGGTPGSGAAAAAGS 249
Query: 433 HP----HISIKSEPVSPSRERSPA------------PPPPAVFPAAR-----PEPGDGLS 471
P S S S +++R A P P P P G
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 472 SPAGGSYETGDRDDGRG 488
GG Y G +D G G
Sbjct: 310 GYPGGDYSGGPQDGGAG 326
>gi|4507205 serum response factor (c-fos serum response
element-binding transcription factor) [Homo sapiens]
Length = 508
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 29/222 (13%)
Query: 2 GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTD 61
GR KI+++ I ++ R TF+KRK G+MKKAYELS L ++ L++ + + ++ +A+
Sbjct: 142 GRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRK 201
Query: 62 MDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSP---EPDGEDSLEQSPLLEDKYR 118
+ ++ S T +I+T N DSP +P + + + E
Sbjct: 202 LQPMI----------TSETGKALIQTC----LNSPDSPPRSDPTTDQRMSATGFEETDLT 247
Query: 119 RASEELDGLFRRYGSTVPA------PNFAMPVTVPVSNQSSLQFSNPSGSLVTPSL--VT 170
E D + PA P + S +++Q S+ +T L V+
Sbjct: 248 YQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVS 307
Query: 171 SSLTDPRLLSPQQPALQRNSVSP----GLPQRPASAGAMLGG 208
+S++ + S L+ P GL Q P S M GG
Sbjct: 308 ASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGG 349
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/159 (35%), Positives = 64/159 (40%), Gaps = 28/159 (17%)
Query: 298 LGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLS 357
L SQ + T P + P L G PF +PT +T L LP P
Sbjct: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPF--LPT--HTQPNLQGPLHPPLPPPHQP---- 592
Query: 358 LGNVTAWQQPQQPQQ--PQQPQPPQQ---QPPQPQQPQPQQPQQPQQPPQQQSHLVPVSL 412
QPQQPQQ P Q QPP Q QPP QP PQ P PQ PPQ Q H L
Sbjct: 593 --------QPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP--PQHPPQHQHHHHHHHL 642
Query: 413 SNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSP 451
S +P PL + PH+ S SR + P
Sbjct: 643 S--VPPPPLMPMSQP---QFRPHVQTAQPQASSSRMQCP 676
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 5/95 (5%)
Query: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAA 427
Q P P P P Q QP QPQQ P Q Q P QPP Q P P P H
Sbjct: 579 QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQ-----PPPQHQPPPQHPPQHPPQH 633
Query: 428 LTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAA 462
H H+S+ P+ P + P P A
Sbjct: 634 QHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQA 668
Score = 46.6 bits (109), Expect = 6e-05
Identities = 42/126 (33%), Positives = 53/126 (42%), Gaps = 29/126 (23%)
Query: 365 QQPQQPQQPQQ-PQPPQQQP------PQPQQP--------QPQQPQQPQQPPQQQSHLVP 409
Q P PQ P P PPQQQP PQP QP P PQ PPQ ++ +
Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMM 371
Query: 410 VSLSNLIPGSPL-----PHV-GAALTVTTHPHISIKSEP---VSPSRERSPAPPPPAVFP 460
++ + P P PH G +T P + + S+P V P +R P PP FP
Sbjct: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGP--QRFPGPPE---FP 426
Query: 461 AARPEP 466
P P
Sbjct: 427 QHTPGP 432
Score = 37.0 bits (84), Expect = 0.044
Identities = 32/117 (27%), Positives = 42/117 (35%), Gaps = 27/117 (23%)
Query: 373 PQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTT 432
P QP Q PP P P QQP + PQ L+PV P P P G +
Sbjct: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQ----HPHHPSPPQGMHMPPQL 365
Query: 433 H-PHISIKSEPVSPSRERS----------------------PAPPPPAVFPAARPEP 466
P + + PV+P + ++ P+ P PAV P P P
Sbjct: 366 ETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGP 422
Score = 34.7 bits (78), Expect = 0.22
Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 32/121 (26%)
Query: 361 VTAWQQPQQPQQPQQPQP---PQQQPPQPQQPQ------PQQPQQPQQPPQQQSHLVPVS 411
VT Q P P P QP+P PQ+ P P+ PQ P QP + P Q P
Sbjct: 396 VTPVQVPLLPV-PSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPP 454
Query: 412 LSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPS------RERSPAPPPPAVFPAARPE 465
+ P + + EP PS R P PPPP + ++ P
Sbjct: 455 PQDRDPF----------------FLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPV 498
Query: 466 P 466
P
Sbjct: 499 P 499
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/169 (33%), Positives = 70/169 (41%), Gaps = 33/169 (19%)
Query: 322 QGLPFSSMPTAYNTDYQ----------LTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQ 371
QGL + +PTA T+ Q + + L +L A SS L + Q QQ Q
Sbjct: 135 QGLVLT-LPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNS-QLQQLQLQLQQQQQQ 192
Query: 372 QPQQPQPPQQQPPQP-------QQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHV 424
Q QQP P Q PQP Q QP QP PQQPP P S P S L
Sbjct: 193 QQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPP-------PASQQPPAPTSQLQQA 245
Query: 425 GAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSP 473
H H +++P SP+++ S P P+ PG GL SP
Sbjct: 246 PQPQQHQPHSHSQNQNQP-SPTQQSSSPPQKPS------QSPGHGLPSP 287
Score = 49.7 bits (117), Expect = 7e-06
Identities = 35/88 (39%), Positives = 38/88 (43%), Gaps = 27/88 (30%)
Query: 365 QQPQQPQQPQQPQPPQQQPPQP-----QQPQPQQPQQ-------------------PQQP 400
QQP QP PQQP P QQPP P Q PQPQQ Q PQ+P
Sbjct: 217 QQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKP 276
Query: 401 PQQQSHLVPVSLSNLIPGSPLPHVGAAL 428
Q H +P S L P +PL V L
Sbjct: 277 SQSPGHGLP---SPLTPPNPLQLVNNPL 301
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 57.8 bits (138), Expect = 2e-08
Identities = 115/484 (23%), Positives = 161/484 (33%), Gaps = 76/484 (15%)
Query: 71 EYNEPHESRTNADI--------IETLRKKGFN--GCDSPEPDGEDSLEQSPLLEDKYRRA 120
E N P +++T ++ +++L + N G P +D+ SP + Y
Sbjct: 83 ETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSI---YSPG 139
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
S E D S PA + P P S Q + P S+T +
Sbjct: 140 SVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPH---PSVTPTGYHA 196
Query: 181 PQQPALQRN-SVSPGLPQR-----PASAGAMLGGD-LNSANGACPSPVGNGYVSARASPG 233
P +P R PG P P G +L G + G S VG + P
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 234 LLPVANGNSLNKVIPAKSPP------------PPTHSTQLGAPSRKPD--LRVI--TSQA 277
P++ +S P PP PP + P+ P LR + S +
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 278 GKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDY 337
GL HL +A G+ +P L P SS A +
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP---PASSSAPAPPMRF 373
Query: 338 QLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPP-----QQQPPQPQQPQ-P 391
+S+ SS A SS S P P PP QPP+ QP P
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 392 QQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALT----VTTHPHISIKSEPVSPSR 447
Q Q PP + ++ SN PG P GA T V+TH H + + +
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 448 ER----------SPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLL 497
++ + PPPP F P P +G SS Y P+LG L
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAF----PHPLEGGSSHHAHPYA----------MSPSLGSL 539
Query: 498 RPAP 501
RP P
Sbjct: 540 RPYP 543
Score = 49.7 bits (117), Expect = 7e-06
Identities = 90/353 (25%), Positives = 116/353 (32%), Gaps = 39/353 (11%)
Query: 133 STVPAPNFAM---PVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRN 189
S+V PN P T P+S SS S P+ ++ L P
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSS------GASGAPPTKPPTTPVGGGNLPSAPPPANFP 295
Query: 190 SVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPA 249
V+P LP PA L N A SP G G A+ PG LP + +++ + +
Sbjct: 296 HVTPNLPPPPA---------LRPLNNASASPPGLG---AQPLPGHLP--SPHAMGQGMGG 341
Query: 250 KSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTT 309
P P T +P P +S A M + A S S+ S +
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 310 PVVSVATPSLLSQ-----GLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAW 364
S A PS L S+ P Y + A S P P G L N A
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 365 QQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPH- 423
P P Q Q QQ QQ QQ QQQ S P PH
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 424 VGAALTVTTHPHISIKSEPVSPS-RERSPAPPPPAVFPAARPEPGDGLSSPAG 475
+ + HP+ +SPS P PP PA P + + P G
Sbjct: 519 LEGGSSHHAHPY------AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/171 (23%), Positives = 57/171 (33%), Gaps = 33/171 (19%)
Query: 365 QQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPL-PH 423
+QP+ +P P + P + Q P P L P ++ G P+ P
Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 424 VGAALTVTTHPH-----------ISIKSEPVS---PSRERS--------PAPPPPAVF-- 459
G A + P+ IS+ S S P++ + P+ PPPA F
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 460 --------PAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPE 502
PA RP S P G+ G +G L P PE
Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPE 347
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 57.8 bits (138), Expect = 2e-08
Identities = 115/484 (23%), Positives = 161/484 (33%), Gaps = 76/484 (15%)
Query: 71 EYNEPHESRTNADI--------IETLRKKGFN--GCDSPEPDGEDSLEQSPLLEDKYRRA 120
E N P +++T ++ +++L + N G P +D+ SP + Y
Sbjct: 83 ETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSI---YSPG 139
Query: 121 SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS 180
S E D S PA + P P S Q + P S+T +
Sbjct: 140 SVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPH---PSVTPTGYHA 196
Query: 181 PQQPALQRN-SVSPGLPQR-----PASAGAMLGGD-LNSANGACPSPVGNGYVSARASPG 233
P +P R PG P P G +L G + G S VG + P
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 234 LLPVANGNSLNKVIPAKSPP------------PPTHSTQLGAPSRKPD--LRVI--TSQA 277
P++ +S P PP PP + P+ P LR + S +
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 278 GKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDY 337
GL HL +A G+ +P L P SS A +
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP---PASSSAPAPPMRF 373
Query: 338 QLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPP-----QQQPPQPQQPQ-P 391
+S+ SS A SS S P P PP QPP+ QP P
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 392 QQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALT----VTTHPHISIKSEPVSPSR 447
Q Q PP + ++ SN PG P GA T V+TH H + + +
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 448 ER----------SPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLL 497
++ + PPPP F P P +G SS Y P+LG L
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAF----PHPLEGGSSHHAHPYA----------MSPSLGSL 539
Query: 498 RPAP 501
RP P
Sbjct: 540 RPYP 543
Score = 49.7 bits (117), Expect = 7e-06
Identities = 90/353 (25%), Positives = 116/353 (32%), Gaps = 39/353 (11%)
Query: 133 STVPAPNFAM---PVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRN 189
S+V PN P T P+S SS S P+ ++ L P
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSS------GASGAPPTKPPTTPVGGGNLPSAPPPANFP 295
Query: 190 SVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPA 249
V+P LP PA L N A SP G G A+ PG LP + +++ + +
Sbjct: 296 HVTPNLPPPPA---------LRPLNNASASPPGLG---AQPLPGHLP--SPHAMGQGMGG 341
Query: 250 KSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTT 309
P P T +P P +S A M + A S S+ S +
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 310 PVVSVATPSLLSQ-----GLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAW 364
S A PS L S+ P Y + A S P P G L N A
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 365 QQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPH- 423
P P Q Q QQ QQ QQ QQQ S P PH
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 424 VGAALTVTTHPHISIKSEPVSPS-RERSPAPPPPAVFPAARPEPGDGLSSPAG 475
+ + HP+ +SPS P PP PA P + + P G
Sbjct: 519 LEGGSSHHAHPY------AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/171 (23%), Positives = 57/171 (33%), Gaps = 33/171 (19%)
Query: 365 QQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPL-PH 423
+QP+ +P P + P + Q P P L P ++ G P+ P
Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 424 VGAALTVTTHPH-----------ISIKSEPVS---PSRERS--------PAPPPPAVF-- 459
G A + P+ IS+ S S P++ + P+ PPPA F
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 460 --------PAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPE 502
PA RP S P G+ G +G L P PE
Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPE 347
>gi|93277088 mediator of RNA polymerase II transcription, subunit 12
homolog (S. cerevisiae)-like [Homo sapiens]
Length = 2145
Score = 56.2 bits (134), Expect = 7e-08
Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 6/66 (9%)
Query: 360 NVTAWQQPQQPQQPQQPQPPQQQP----PQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNL 415
N+ + PQ P +P+QPQ QQQ QPQQPQPQQP QPQQ Q QS + L +
Sbjct: 2038 NLPSVPLPQDPMRPRQPQVRQQQRLLQMQQPQQPQPQQPPQPQQSSQSQSQ--TLGLQAM 2095
Query: 416 IPGSPL 421
P PL
Sbjct: 2096 QPQQPL 2101
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/74 (47%), Positives = 37/74 (50%), Gaps = 11/74 (14%)
Query: 336 DYQLTSAE--LSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQ 393
D LTSA L S+P P V Q+ Q QQPQQPQP QQPPQPQQ Q
Sbjct: 2029 DAVLTSAHPNLPSVPLPQDPMRPRQPQVRQQQRLLQMQQPQQPQP--QQPPQPQQSSQSQ 2086
Query: 394 PQ-------QPQQP 400
Q QPQQP
Sbjct: 2087 SQTLGLQAMQPQQP 2100
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/38 (55%), Positives = 22/38 (57%)
Query: 366 QPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQ 403
QPQQP QPQQ Q Q Q QPQQP P+Q QQ
Sbjct: 2072 QPQQPPQPQQSSQSQSQTLGLQAMQPQQPLFPRQGLQQ 2109
Score = 39.3 bits (90), Expect = 0.009
Identities = 22/40 (55%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 365 QQPQQPQ--QPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQ 402
QQPQQPQ QP QPQ Q Q Q QPQQP P Q
Sbjct: 2066 QQPQQPQPQQPPQPQQSSQSQSQTLGLQAMQPQQPLFPRQ 2105
Score = 33.9 bits (76), Expect = 0.37
Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 365 QQPQQPQQPQQPQPPQ--QQPPQPQQPQ-PQQPQQPQQPPQQQSHLV 408
QQP QPQQ Q Q Q QPQQP P+Q Q Q QQ + LV
Sbjct: 2074 QQPPQPQQSSQSQSQTLGLQAMQPQQPLFPRQGLQQTQQQQQTAALV 2120
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 55.8 bits (133), Expect = 9e-08
Identities = 86/320 (26%), Positives = 115/320 (35%), Gaps = 53/320 (16%)
Query: 178 LLSPQQPALQRNSVSPGLPQRP----ASAGAM------LGGDLNSANGACPSPVGNGYVS 227
LLSPQQ Q+ ++ PG+P +P +S GA+ G + N+ + A S G +
Sbjct: 3984 LLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
Query: 228 ARASP---GLLPVANGNSLNKVIPAKS-----------PPPPTHSTQLGAPSRKPDLRVI 273
+ P G P + +V P+ S P P S QL P R P
Sbjct: 4044 HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG---- 4099
Query: 274 TSQAGKGLMHHL-TEDHLDLNNAQRLGVSQSTHSLTTPVVSVA------TPSLLSQGLPF 326
Q L+H H L + S H L P VS+ T +LL P
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 327 SSMPTAYNTDYQLTSAELSSLPAFSSPGGL-------SLGNVTAWQQPQQPQQPQ----Q 375
P NT Q P S GL ++G + A Q + PQ
Sbjct: 4160 LERPMQNNTGPQPPKPG----PVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLS 4215
Query: 376 PQPPQQQPPQPQQPQPQQPQQPQQ-PPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHP 434
PQ QQ Q Q QQ Q +Q PP Q+ L L+ P +G T P
Sbjct: 4216 PQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLL--GCQPQLGGFPGPQTGP 4273
Query: 435 HISIKSEPVSPSRERSPAPP 454
+ + P R PAPP
Sbjct: 4274 LQELGAGPRPQGPPRLPAPP 4293
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 6/110 (5%)
Query: 367 PQQPQQPQQPQPPQQQPPQPQQPQPQQP---QQPQQPPQQQSHLVPVSLSNLIPGSPLPH 423
P + P P P +P + P P + P PP + S P+ S L P P
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 424 VGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSP 473
A T + P ++ P+SP E SP PPP P + P LS P
Sbjct: 529 SPALETPLSPPP---EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575
Score = 48.5 bits (114), Expect = 1e-05
Identities = 101/431 (23%), Positives = 145/431 (33%), Gaps = 64/431 (14%)
Query: 132 GSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPS-------LVTSSL-TDPRLLSPQQ 183
G +P + ++ Q Q S +GSL PS L SL D RLL +Q
Sbjct: 3661 GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720
Query: 184 PALQRNSVSPG----------------LPQRPASAGAMLGGDLNSANGACPSPVG----- 222
LQ+ + L Q G + + P P G
Sbjct: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 223 --NGYVSARASP-------GLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSR---KPDL 270
G + + SP G+L A L + P P H L SR P L
Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
Query: 271 RVITSQAGKGLMHH----LTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPF 326
+Q G+GLM H + + Q+ ++ +H + + P L +Q +
Sbjct: 3841 ----AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGS 3896
Query: 327 SSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQP 386
Q + L + QQ QQ QQ QQ Q QQQ
Sbjct: 3897 LQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ 3956
Query: 387 QQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPH---VGAALTVTTHPHISIKSEPV 443
QQ Q QQ Q QQ QQQ L+ S + L P +G + H S +
Sbjct: 3957 QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFS-SPGAL 4015
Query: 444 SPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGR----GDFGPTLG---- 495
P+ + V PA E +G S+ GG G + G+ P+L
Sbjct: 4016 GPTLLLT-GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQ 4074
Query: 496 --LLRPAPEPE 504
L++P P+P+
Sbjct: 4075 LLLVQPQPQPQ 4085
Score = 48.1 bits (113), Expect = 2e-05
Identities = 83/364 (22%), Positives = 115/364 (31%), Gaps = 72/364 (19%)
Query: 194 GLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGL---------LPVANGNSLN 244
G P PA G L G+ P P G + + P + +A L
Sbjct: 2127 GSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE 2186
Query: 245 KVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQ-AGKGLMHHLTEDHLDLNNAQRLGVSQS 303
P P P + + GAP++ P L + AG+ H T G +
Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP----------GTPRH 2236
Query: 304 THSLTTPVVSVATPSLLSQGLPFSS------------MPTAYNTD---YQLTSAEL-SSL 347
S P + PSL + +P S P + ++ EL +S
Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASS 2296
Query: 348 PAFSSP--------------GGLSLGNVTAWQQPQQPQQPQ-QPQPP-----QQQPPQPQ 387
P++ P GGL L ++ P P+ Q +PQ P Q+PP Q
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356
Query: 388 QPQPQQPQQPQ-------QPPQQQSHLVPVSLSNLIPGSPLPHVGAAL---TVTTHPHIS 437
P P P P Q L P P P P AL ++ + P
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTP------RPQPPPPESCCALPPRSLPSDPFSR 2410
Query: 438 IKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLL 497
+ + P S S +SP P P A P P R R F P
Sbjct: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
Query: 498 RPAP 501
RP P
Sbjct: 2471 RPQP 2474
Score = 47.0 bits (110), Expect = 4e-05
Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 358 LGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIP 417
LG +PQ + P + P PP+ P + P PP + S L P +P
Sbjct: 419 LGKAGVQLEPQL-EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE--LP 475
Query: 418 GSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFP 460
SPLP H ++ P+SP E SP PPP P
Sbjct: 476 ASPLPEA-------LHLSRPLEESPLSPPPEESPLSPPPESSP 511
Score = 46.2 bits (108), Expect = 7e-05
Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 23/163 (14%)
Query: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPV-SLSNLIP---GSPLPH 423
+ P P + P PP+ + P + P PP ++S L P S L P SP+
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 424 VGAALTVTTHPHISIKSE-PV----SPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSY 478
++ P +S S PV SP E SP PPP P + P LS P S
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697
Query: 479 ETGDRDDGRGDFGPTLGL---------LRPAPE-----PEAEG 507
+ +D P L L P PE P +EG
Sbjct: 698 TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Score = 45.8 bits (107), Expect = 9e-05
Identities = 56/221 (25%), Positives = 78/221 (35%), Gaps = 33/221 (14%)
Query: 306 SLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFS--SPGGLSLGNVTA 363
S T+P + S + LP S +P A + L + LS P S SP S
Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL 515
Query: 364 WQQPQQPQQPQQPQP----PQQQPPQ-----------PQQPQPQQ-PQQPQ------QPP 401
+ P P + P P P PP+ P P P++ P P PP
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575
Query: 402 QQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPA 461
++S + P + P SP P + P+SP E SP PPP
Sbjct: 576 PEESPMSPPPEES--PMSPPPEASRLFP-------PFEESPLSPPPEESPLSPPPEASRL 626
Query: 462 ARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPE 502
+ P +S P S + + R P + L P PE
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE 667
Score = 45.1 bits (105), Expect = 2e-04
Identities = 85/385 (22%), Positives = 125/385 (32%), Gaps = 72/385 (18%)
Query: 137 APNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLP 196
+P P PV + L P S ++P L+ S P L++ +SP P
Sbjct: 807 SPQTEEPHLSPVPEEPCLS-PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR-P 864
Query: 197 QRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPT 256
++P G CP+P P L P+ +L++ P + P P
Sbjct: 865 EKPPEEP-----------GQCPAPEELPLFPPPGEPSLSPLLGEPALSE--PGEPPLSPL 911
Query: 257 HSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVAT 316
+PS +P L + +L +P+++ A
Sbjct: 912 PEELPLSPSGEPSL------------------------SPQLMPPDPLPPPLSPIITAAA 947
Query: 317 PSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQP 376
P LS P + + + P +P P+ +P
Sbjct: 948 PPALS---PLGELEYPFGAKGDSDPESPLAAPILETPIS---------PPPEANCTDPEP 995
Query: 377 QPPQQQPPQPQQPQP------QQPQQPQQPPQQQSHLV----------PVSLSNLIPGSP 420
PP PP P P +P PQ P Q LV P +L +P SP
Sbjct: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP-SP 1054
Query: 421 LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET 480
L +G + V+ + + E S PA P A P P P LS PA
Sbjct: 1055 LSPIGKVVGVSDEAELH-EMETEKVSEPECPALEPSATSPL--PSPMGDLSCPAPSPAPA 1111
Query: 481 GDRDDGRG-DFGPTLGLLRPAPEPE 504
D G G D P G+ P +PE
Sbjct: 1112 LDDFSGLGEDTAPLDGIDAPGSQPE 1136
Score = 40.4 bits (93), Expect = 0.004
Identities = 86/370 (23%), Positives = 117/370 (31%), Gaps = 83/370 (22%)
Query: 160 SGSLVTPSLVTSSLTDPRLLSPQQP-ALQRNSVSPGLPQRPASAGAMLGGDLNSANGACP 218
SGS S V L P + QP ++ +N + P P ML + + G P
Sbjct: 4121 SGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP--------MLERPMQNNTGPQP 4172
Query: 219 SPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAG 278
G S + PG+ + L + G ++ P LR ++ Q
Sbjct: 4173 PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQ-------------GVLAKNPQLRHLSPQQQ 4219
Query: 279 KGLMHHLTEDHLDLNNAQRLGVS-QSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDY 337
+ L L + L + A R Q + T+P+ + G P
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279
Query: 338 QLTSAELSSLPAFSSPGGLSLGNVTAWQQP-QQPQQPQQPQPPQQQPPQPQQPQPQQPQQ 396
LPA PG LS G V P P PQ+P+ P Q P P Q P +
Sbjct: 4280 GPRPQGPPRLPA--PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLP----SPSSQLPTE 4333
Query: 397 PQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPP 456
Q PP PG+P +P P+ E PPP
Sbjct: 4334 AQLPPTH-------------PGTP--------------------KPQGPTLE----PPPG 4356
Query: 457 AVFPAARP-------------EPGDGLS---SPAGGSYETGDRDDGRGDFGPTLGLLRPA 500
V PAA +P D L+ P S G D G P L
Sbjct: 4357 RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIK 4416
Query: 501 PEPEAEGSAV 510
EP E A+
Sbjct: 4417 QEPREEPCAL 4426
Score = 38.1 bits (87), Expect = 0.020
Identities = 82/360 (22%), Positives = 128/360 (35%), Gaps = 42/360 (11%)
Query: 143 PVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPG---LPQRP 199
P + P S S P S +P+L T L+ P SP P + + +SP LP P
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETP-LSPPPEASPLSPPFEESPLSPPPEELPTSP 565
Query: 200 ASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSP-PPPTHS 258
+ L + + P P + + L P + L+ P +SP PP +
Sbjct: 566 PPEASRLSPPPEESPMS-PPPEESPMSPPPEASRLFPPFEESPLSPP-PEESPLSPPPEA 623
Query: 259 TQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVAT-- 316
++L P + ++ ++ L RL L+ P T
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLS-PLPVVSRLSPPPEESPLSPPPEESPTSP 682
Query: 317 -PSLLSQGLPFSSMPTAYNTDYQLTSA----ELSSLPAFSSPGGLSLGNVTAWQQPQ--- 368
P P PT+ + S L SLP SP + ++PQ
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP------LLPLPEEPQLCP 736
Query: 369 ---------QPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQP----PQQQSHLVPVSLSNL 415
+P++P P++ PQ +P QP++P ++ HL P +
Sbjct: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
Query: 416 IPGSPLPHVGAALTVTTHPHIS-IKSEP-VSPSRERSPAPPPPAVFPAARPEPGDGLSSP 473
+ SP P T PH+S + EP +SP E S P + P P P + SP
Sbjct: 797 L--SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL-SPQSEEPCLSPRPEESHLSP 853
Score = 36.2 bits (82), Expect = 0.075
Identities = 46/166 (27%), Positives = 65/166 (39%), Gaps = 30/166 (18%)
Query: 366 QPQQPQ-QPQQPQP-----PQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLI--P 417
QP++ PQ +P P++ P+ +P +P++PP++ L P
Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886
Query: 418 GSP--LPHVG-AALTVTTHPHISIKSE--PVSPSRERS-------PAPPPPAVFPAARPE 465
G P P +G AL+ P +S E P+SPS E S P P PP + P
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA 946
Query: 466 PGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRP------APEPEA 505
LS Y G +GD P L P +P PEA
Sbjct: 947 APPALSPLGELEYPFG----AKGDSDPESPLAAPILETPISPPPEA 988
Score = 32.7 bits (73), Expect = 0.83
Identities = 107/447 (23%), Positives = 146/447 (32%), Gaps = 92/447 (20%)
Query: 121 SEELDGLFRRYGSTVPAPN------FAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLT 174
S DG + +VP P+ +P VP S F + P T+ T
Sbjct: 2136 STSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPT 2195
Query: 175 DPRLLSP-----QQPALQRNS------------VSPGLPQ-RPASAGAMLGGDLNSA-NG 215
P SP Q P L +S PG P+ +P++ L S N
Sbjct: 2196 YPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNL 2255
Query: 216 ACPSPVGNGYVSARASPGLLPVANGNS----------LNKVIPAKSPP------PPTHST 259
A P G G A + P L P G S L P+ PP P+ T
Sbjct: 2256 AVPESPGVGGGKA-SEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGT 2314
Query: 260 QLGAPSRK-PDL----------RVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTH--- 305
LG K PD+ +V G GL + AQ L S +H
Sbjct: 2315 HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ------EPPPAQALAPSPPSHPDI 2368
Query: 306 ----SLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNV 361
S T P A P L + P L S S +PA SP
Sbjct: 2369 FRPGSYTDPY---AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPA--SP-------- 2415
Query: 362 TAWQQPQQPQQPQQPQPPQQQP--PQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGS 419
Q Q P P+P + P P P+ Q P +PP + P + + P
Sbjct: 2416 ---QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472
Query: 420 PLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYE 479
P V A + H S+ + + PA A P+ +P + + SP G++
Sbjct: 2473 QPPEV--AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG--QPPNFVRSPGTGAF- 2527
Query: 480 TGDRDDGRGDFGPTLG---LLRPAPEP 503
G R F +G L P P+P
Sbjct: 2528 VGTPSPMRFTFPQAVGEPSLKPPVPQP 2554
Score = 32.7 bits (73), Expect = 0.83
Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 16/90 (17%)
Query: 318 SLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQ 377
SLL Q P PT ++ Y +++ ++ L A P++P P P
Sbjct: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA---------------PPPEEPSPPPSPL 4921
Query: 378 PPQQQPPQPQQPQPQQPQQPQQPPQQQSHL 407
P P P +P + P +P P S L
Sbjct: 4922 APSPASP-PTEPLVELPTEPLAEPPVPSPL 4950
Score = 30.4 bits (67), Expect = 4.1
Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 31/118 (26%)
Query: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQP---QQPQQPPQQQSHLVPVSLSNL 415
G+VT+ QP++P Q P + +PQ + P + P PP ++S
Sbjct: 399 GHVTS-MQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEES---------- 447
Query: 416 IPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSP 473
P SP P + P SP E S PPP PA+ LS P
Sbjct: 448 -PLSPPP----------------EESPTSPPPEASRLSPPPEELPASPLPEALHLSRP 488
Score = 29.3 bits (64), Expect = 9.1
Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 7/122 (5%)
Query: 354 GGLSLGNVTAWQQP--QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVS 411
GG ++ +V P + P+ P +P QP+ Q P+
Sbjct: 354 GGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQ 413
Query: 412 LSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLS 471
PL G L ++ + P+ P E SP PPP P + P LS
Sbjct: 414 CE----AKPLGKAGVQLEPQLEAPLN-EEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468
Query: 472 SP 473
P
Sbjct: 469 PP 470
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 55.8 bits (133), Expect = 9e-08
Identities = 90/399 (22%), Positives = 130/399 (32%), Gaps = 64/399 (16%)
Query: 140 FAMPVTVPVSNQSSLQFSNPSGSLVT---------PSLVTSSLTDPRLLSPQQPALQRNS 190
F MPV++ + + P+G T PS V T L+ P PA
Sbjct: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
Query: 191 VSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARAS-PGLLPVANGNSLNKVIPA 249
+P L +PA A A +P+ G +A P P A
Sbjct: 615 AAPVLTVQPAP----------QAPPAVSTPLPLGLQQPQAQQPPQAPTPQ---------A 655
Query: 250 KSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDL----NNAQRLGVSQSTH 305
+PP T + P+ V+ LT+D L + +Q+ ++ H
Sbjct: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
Query: 306 SLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQ 365
V V+ P P + + Q ++ S PA P L
Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775
Query: 366 QPQQPQQ-----------PQQPQPPQQQPPQPQ---QPQPQQPQQPQQPPQQQSHLVPVS 411
P P Q P +PP + P +PQ +P + P P PPQ L +
Sbjct: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 412 LSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLS 471
+ G P P ++P + P P R +S PP P A P S
Sbjct: 836 VIQNQLGVPPP--------ASNPAPTAPGPPQPPLRPQS--QPPEGPLPPAPHLPPSSTS 885
Query: 472 SPAGGSYETGDR------DDGRGDFGPTLGLLR-PAPEP 503
S S ET R D + F P+ G + P P P
Sbjct: 886 SAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP 924
Score = 50.1 bits (118), Expect = 5e-06
Identities = 97/382 (25%), Positives = 132/382 (34%), Gaps = 80/382 (20%)
Query: 132 GSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSV 191
G+ P P A+ S S+ N S+V P+ + LL P PA+Q
Sbjct: 433 GAAPPQPPGAL------SKPMSVHLLNQGSSIVIPAQHMLPGQNQFLL-PGAPAVQ---- 481
Query: 192 SPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKS 251
LPQ+ ++ A +GG + +A +P G + A +A SL V+ +
Sbjct: 482 ---LPQQLSALPANVGGQILAA----AAPHTGGQLIANPILTNQNLAGPLSLGPVL---A 531
Query: 252 PPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPV 311
P HS + L Q G+ + + S T S P
Sbjct: 532 PHSGAHSAHI--------LSAAPIQVGQPALFQMP--------VSLAAGSLPTQSQPAPA 575
Query: 312 VSVATPSLLSQGLPFSSMPTAYNTDYQLTSAE-----------LSSLPAFSSPGGLSLGN 360
AT L LP S++ D + A L+ PA +P +S
Sbjct: 576 GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPL 635
Query: 361 VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQ--PQQPQ-----QPPQ--QQSHLVPVS 411
QQPQ Q PQ P P PPQ PQP P+ QPP + L S
Sbjct: 636 PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDS 695
Query: 412 LSNLIP----GSPLPHVGAALTVTTHPHISIKSE-----------------PVSPSRERS 450
L +P PL G L+V +S P +P + S
Sbjct: 696 LQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS 755
Query: 451 PAPPPPAVFPAARPEPGDGLSS 472
PAP P PAA P G G SS
Sbjct: 756 PAPAPQ--IPAAAPLKGPGPSS 775
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/317 (22%), Positives = 105/317 (33%), Gaps = 51/317 (16%)
Query: 196 PQRPASAGAMLGGDLNSANGACPSPV----------GNGYVSARASPGLLPVANGNSLNK 245
P P + GA LG + A P+P G G S+ + P P+ + L
Sbjct: 735 PATPVAKGAGLGPQAPDSQ-ASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793
Query: 246 VIPAKSPP-PPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQST 304
P + P PP+ + P +P L + + + N +LGV
Sbjct: 794 PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI----FVIQN--QLGVPPPA 847
Query: 305 HSLTTPVVSVATPSLLSQGLPFSS-------MPTAYNTDYQLTSAELSSLPAFSSPGGLS 357
+ P L Q P +P + + +S+E SS +P
Sbjct: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
Query: 358 LGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQP-------PQ-----QQS 405
L + Q P + P P P+P P P P+ Q PQ ++
Sbjct: 908 L----QFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERF 963
Query: 406 HLVP--VSLSNLIPGSP-LPHVGAALTVTTHPHISI-------KSEPVSPSRERSPAPPP 455
H VP + L N G+P P +L T P S+ P +PS +PAP
Sbjct: 964 HQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
Query: 456 PAVFPAARPEPGDGLSS 472
P P +S
Sbjct: 1024 ATGLPPLLPAENKAFAS 1040
Score = 30.4 bits (67), Expect = 4.1
Identities = 98/417 (23%), Positives = 139/417 (33%), Gaps = 98/417 (23%)
Query: 92 GFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPV------T 145
G G D P + SL+++ + E A ELD + + PA A P
Sbjct: 93 GSGGADQPCDILQQSLQEANITEQTLE-AEAELDLGPFQLPTLQPADGGAGPTGAGGAAA 151
Query: 146 VPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAM 205
V Q+ S L P V LT L+ PQ + SV P L
Sbjct: 152 VAAGPQALFPGSTDLLGLQGPPTV---LTHQALVPPQDVVNKALSVQPFL---------- 198
Query: 206 LGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPS 265
PVG G V+ + PGL + NG SP T +T AP
Sbjct: 199 -------------QPVGLGNVTLQPIPGLQGLPNG----------SPGGATAATLGLAPI 235
Query: 266 R---KPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQ 322
+ +P + + T + +L A G S+ +L + VS L+ Q
Sbjct: 236 QVVGQPVMALNTPTSQLLAKQVPVSGYL----ASAAGPSEPV-TLASAGVSPQGAGLVIQ 290
Query: 323 GLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQ-- 380
+++ T N + A +S P +P G L P P P P
Sbjct: 291 KNLSAAVATTLNGNSVFGGAGAASAPT-GTPSGQPLAVA-----PGLGSSPLVPAPNVIL 344
Query: 381 QQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKS 440
+ P P QP+P + ++P L L P P GA LT+ P ++
Sbjct: 345 HRTPTPIQPKP-------------AGVLPPKLYQLTP-KPFAPAGATLTIQGEPG-ALPQ 389
Query: 441 EPVSPSR---------------ERSPAP---------PPPAVFPAARPEPGDGLSSP 473
+P +P PAP PP AA P+P LS P
Sbjct: 390 QPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKP 446
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,621,733
Number of Sequences: 37866
Number of extensions: 1803715
Number of successful extensions: 33025
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 595
Number of HSP's successfully gapped in prelim test: 1151
Number of HSP's that attempted gapping in prelim test: 12755
Number of HSP's gapped (non-prelim): 9620
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.