Guide to the Human Genome
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Name: MED12L Sequence: fasta or formatted (2145aa) NCBI GI: 93277088
Description:

mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)-like

Referenced in:

RNA Polymerase and General Transcription Factors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5        140           3
 C cysteine            2.2         48           2
 D aspartate           4.5         96           3
 E glutamate           5.4        115           6
 F phenylalanine       3.0         65           2
 G glycine             5.1        110           3
 H histidine           2.4         52           2
 I isoleucine          4.0         86           2
 K lysine              5.2        112           3
 L leucine            11.4        244           4
 M methionine          2.7         57           2
 N asparagine          4.6         99           2
 P proline             6.3        135           2
 Q glutamine           8.6        184           6
 R arginine            4.9        105           2
 S serine              9.3        199           4
 T threonine           4.8        102           3
 V valine              5.4        116           2
 W tryptophan          1.2         25           1
 Y tyrosine            2.6         55           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mediator of RNA polymerase II transcription, subunit... 
MED12                 0.560   mediator complex subunit 12 
MLL2                  0.018   myeloid/lymphoid or mixed-lineage leukemia 2 
PAXIP1                0.014   PAX interacting protein 1 
MAML2                 0.013   mastermind-like 2 
MED15                 0.011   mediator complex subunit 15 isoform a 
MED15                 0.011   mediator complex subunit 15 isoform b 
ZNF853                0.011   zinc finger protein 853 
EP300                 0.009   E1A binding protein p300 
MN1                   0.009   meningioma  1 
ARID1A                0.008   AT rich interactive domain 1A isoform a 
ARID1A                0.008   AT rich interactive domain 1A isoform b 
NFAT5                 0.008   nuclear factor of activated T-cells 5 isoform a [Hom...
NFAT5                 0.008   nuclear factor of activated T-cells 5 isoform c [Homo...
NFAT5                 0.008   nuclear factor of activated T-cells 5 isoform d [Ho...
NFAT5                 0.008   nuclear factor of activated T-cells 5 isoform b [Ho...
NFAT5                 0.008   nuclear factor of activated T-cells 5 isoform a [Hom...
MAML3                 0.007   mastermind-like 3 
FOXP2                 0.007   forkhead box P2 isoform I 
BPTF                  0.007   bromodomain PHD finger transcription factor isoform ...
MEF2D                 0.007   myocyte enhancer factor 2D 
CREBBP                0.007   CREB binding protein isoform b 
CREBBP                0.007   CREB binding protein isoform a 
AAK1                  0.007   AP2 associated kinase 1 
FOXP2                 0.007   forkhead box P2 isoform III 
FOXP2                 0.007   forkhead box P2 isoform II 
NCOA6                 0.007   nuclear receptor coactivator 6 
TOX3                  0.007   TOX high mobility group box family member 3 isoform...
TOX3                  0.007   TOX high mobility group box family member 3 isoform...
PHC1                  0.007   polyhomeotic 1-like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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