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Search of human proteins with 50897284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50897284 peptidyl-tRNA hydrolase 1 homolog [Homo sapiens]
(214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50897284 peptidyl-tRNA hydrolase 1 homolog [Homo sapiens] 432 e-122
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 32 0.53
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 30 1.2
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 30 2.0
gi|42794271 iodotyrosine dehalogenase 1 [Homo sapiens] 30 2.0
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 29 2.6
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 29 2.6
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 29 2.6
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 29 3.4
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 28 4.5
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 28 4.5
gi|169160873 PREDICTED: similar to hCG2040319 [Homo sapiens] 28 5.8
gi|239747400 PREDICTED: similar to hCG2040319 [Homo sapiens] 28 5.8
gi|239741226 PREDICTED: similar to hCG2040319 [Homo sapiens] 28 5.8
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 28 5.8
gi|239755810 PREDICTED: hypothetical protein [Homo sapiens] 28 7.6
gi|239750310 PREDICTED: hypothetical protein [Homo sapiens] 28 7.6
gi|239744621 PREDICTED: hypothetical protein [Homo sapiens] 28 7.6
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 28 7.6
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 28 7.6
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 28 7.6
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 28 7.6
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 28 7.6
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] 28 7.6
gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo... 27 10.0
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 27 10.0
gi|38505218 putative acyl-CoA dehydrogenase [Homo sapiens] 27 10.0
gi|118498339 EMI domain containing 2 [Homo sapiens] 27 10.0
>gi|50897284 peptidyl-tRNA hydrolase 1 homolog [Homo sapiens]
Length = 214
Score = 432 bits (1112), Expect = e-122
Identities = 214/214 (100%), Positives = 214/214 (100%)
Query: 1 MRPGGFLGAGQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRL 60
MRPGGFLGAGQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRL
Sbjct: 1 MRPGGFLGAGQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRL 60
Query: 61 GVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVH 120
GVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVH
Sbjct: 61 GVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVH 120
Query: 121 DELDKPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPAHPEAVQAHVLGCF 180
DELDKPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPAHPEAVQAHVLGCF
Sbjct: 121 DELDKPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPAHPEAVQAHVLGCF 180
Query: 181 SPAEQELLPLLLDRATDLILDHIRERSQGPSLGP 214
SPAEQELLPLLLDRATDLILDHIRERSQGPSLGP
Sbjct: 181 SPAEQELLPLLLDRATDLILDHIRERSQGPSLGP 214
>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
Length = 540
Score = 31.6 bits (70), Expect = 0.53
Identities = 14/28 (50%), Positives = 16/28 (57%)
Query: 16 AMSRCVLEPRPPGKRWMVAGLGNPGLPG 43
A S CV P PPG+R G+PG PG
Sbjct: 112 APSECVCPPGPPGRRGKPGRRGDPGPPG 139
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 30.4 bits (67), Expect = 1.2
Identities = 44/148 (29%), Positives = 57/148 (38%), Gaps = 27/148 (18%)
Query: 23 EPRPPGKRWMVAGLGNPGLPGTRHSVGMAVL--GQLARRLGVAESWTR------------ 68
+P PP +G P H+ G AVL G L A +WT
Sbjct: 19 DPGPPANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAPNWTGLQTLLQQLPPQD 78
Query: 69 --DRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAA--ELFGLTAEEVYLVHDELD 124
+R+C LAL A+L L RR A G+ VAR +L G T E+ EL
Sbjct: 79 IDERYC---LALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKC----RELL 131
Query: 125 KP--LGRLALKLGGSARGHNGVRSCISC 150
KP G A + G H +C +C
Sbjct: 132 KPGEYGVFAARAGEQRCWHQPCFACQAC 159
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 29.6 bits (65), Expect = 2.0
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 7/47 (14%)
Query: 16 AMSRCVLEPRPPGKRWMVAGLGNP----GLPGTRHSVGMAVLGQLAR 58
A +R VLE PPG W+ LG P LP G+ LG++AR
Sbjct: 243 ARARRVLEAVPPGPHWL---LGTPLPPKALPTAGLPPGLLALGEVAR 286
>gi|42794271 iodotyrosine dehalogenase 1 [Homo sapiens]
Length = 289
Score = 29.6 bits (65), Expect = 2.0
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 154 NAMPRLRVGIGRPAHPEAVQAHVLGCFSPAEQELLPLLLDRATDLIL 200
N PRLRV +GRPAH + + +G P+++ +P L + D I+
Sbjct: 242 NCGPRLRVLLGRPAHEKLLMLLPVG--YPSKEATVPDLKRKPLDQIM 286
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 29.3 bits (64), Expect = 2.6
Identities = 13/26 (50%), Positives = 15/26 (57%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PPG + + GNPGLPG VG
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVG 1152
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 29.3 bits (64), Expect = 2.6
Identities = 13/26 (50%), Positives = 15/26 (57%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PPG + + GNPGLPG VG
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVG 1152
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 29.3 bits (64), Expect = 2.6
Identities = 13/26 (50%), Positives = 15/26 (57%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PPG + + GNPGLPG VG
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVG 1152
>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
Length = 680
Score = 28.9 bits (63), Expect = 3.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 3 PGGFLGA-GQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGM 50
P G+ GA G+R S +P PGK + GNPGLPG + G+
Sbjct: 369 PAGYPGAKGERGSPGSDG---KPGYPGKPGLDGPKGNPGLPGPKGDPGV 414
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 28.5 bits (62), Expect = 4.5
Identities = 13/31 (41%), Positives = 16/31 (51%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVGMAVLG 54
P P G R G PGLPG + +VG +G
Sbjct: 660 PGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 690
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 28.5 bits (62), Expect = 4.5
Identities = 13/23 (56%), Positives = 15/23 (65%), Gaps = 2/23 (8%)
Query: 23 EPRPPGKRWMVA--GLGNPGLPG 43
EP PPG R + G+G PGLPG
Sbjct: 195 EPGPPGDRGLKGDNGVGQPGLPG 217
>gi|169160873 PREDICTED: similar to hCG2040319 [Homo sapiens]
Length = 274
Score = 28.1 bits (61), Expect = 5.8
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 118 LVHDELDKPLGRLALKLGGSARG--HNGVR------SCISCLNSNAMPRLRVGIGRPAHP 169
++ ++ +P+ KL GS H G+ SC S +NS+ R + R
Sbjct: 67 IIREQQTRPIWTAEDKLDGSLEDNPHRGLADSSADLSCDSRVNSDYWRRRKARAARTLMA 126
Query: 170 EAVQAHVLGCFSPAEQELLPLLLDRATD 197
A Q G ++ A+ EL LDR+++
Sbjct: 127 SATQTASGGPYTDADDELPAPALDRSSE 154
>gi|239747400 PREDICTED: similar to hCG2040319 [Homo sapiens]
Length = 274
Score = 28.1 bits (61), Expect = 5.8
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 118 LVHDELDKPLGRLALKLGGSARG--HNGVR------SCISCLNSNAMPRLRVGIGRPAHP 169
++ ++ +P+ KL GS H G+ SC S +NS+ R + R
Sbjct: 67 IIREQQTRPIWTAEDKLDGSLEDNPHRGLADSSADLSCDSRVNSDYWRRRKARAARTLMA 126
Query: 170 EAVQAHVLGCFSPAEQELLPLLLDRATD 197
A Q G ++ A+ EL LDR+++
Sbjct: 127 SATQTASGGPYTDADDELPAPALDRSSE 154
>gi|239741226 PREDICTED: similar to hCG2040319 [Homo sapiens]
Length = 274
Score = 28.1 bits (61), Expect = 5.8
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 118 LVHDELDKPLGRLALKLGGSARG--HNGVR------SCISCLNSNAMPRLRVGIGRPAHP 169
++ ++ +P+ KL GS H G+ SC S +NS+ R + R
Sbjct: 67 IIREQQTRPIWTAEDKLDGSLEDNPHRGLADSSADLSCDSRVNSDYWRRRKARAARTLMA 126
Query: 170 EAVQAHVLGCFSPAEQELLPLLLDRATD 197
A Q G ++ A+ EL LDR+++
Sbjct: 127 SATQTASGGPYTDADDELPAPALDRSSE 154
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 28.1 bits (61), Expect = 5.8
Identities = 12/30 (40%), Positives = 18/30 (60%)
Query: 27 PGKRWMVAGLGNPGLPGTRHSVGMAVLGQL 56
PG+ +V G PG PG + + G+ V GQ+
Sbjct: 213 PGEPGLVGPPGQPGRPGLKGNPGVGVKGQM 242
>gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]
Length = 499
Score = 27.7 bits (60), Expect = 7.6
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 4/54 (7%)
Query: 125 KPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPA---HPEAVQAH 175
+PLG L + GG + GH R+ S A PR R RP H EA H
Sbjct: 436 RPLGPLRPRAGGQSSGHPD-RTVTSPRPIPARPRPRTSASRPGPSPHLEATGTH 488
>gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]
Length = 499
Score = 27.7 bits (60), Expect = 7.6
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 4/54 (7%)
Query: 125 KPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPA---HPEAVQAH 175
+PLG L + GG + GH R+ S A PR R RP H EA H
Sbjct: 436 RPLGPLRPRAGGQSSGHPD-RTVTSPRPIPARPRPRTSASRPGPSPHLEATGTH 488
>gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
Length = 536
Score = 27.7 bits (60), Expect = 7.6
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 4/54 (7%)
Query: 125 KPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPA---HPEAVQAH 175
+PLG L + GG + GH R+ S A PR R RP H EA H
Sbjct: 473 RPLGPLRPRAGGQSSGHPD-RTVTSPRPIPARPRPRTSASRPGPSPHLEATGTH 525
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 27.7 bits (60), Expect = 7.6
Identities = 11/20 (55%), Positives = 13/20 (65%)
Query: 24 PRPPGKRWMVAGLGNPGLPG 43
P PPG +V G+PGLPG
Sbjct: 2229 PGPPGPSGLVGPQGSPGLPG 2248
Score = 27.3 bits (59), Expect = 10.0
Identities = 13/26 (50%), Positives = 14/26 (53%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PPG + LG PGLPG VG
Sbjct: 2379 PGPPGPPGVKGDLGLPGLPGAPGVVG 2404
>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
sapiens]
Length = 1691
Score = 27.7 bits (60), Expect = 7.6
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PGK + +G+PGLPG++ + G
Sbjct: 726 PGLPGKDGLPGMIGSPGLPGSKGATG 751
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 27.7 bits (60), Expect = 7.6
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 10/57 (17%)
Query: 3 PGGFLGA----------GQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVG 49
P GF GA G+R ++ EP PPG+ G PGLPG + G
Sbjct: 1052 PPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERG 1108
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 27.7 bits (60), Expect = 7.6
Identities = 15/33 (45%), Positives = 17/33 (51%)
Query: 22 LEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLG 54
LEP PP R VA G PG P +R A+ G
Sbjct: 1190 LEPAPPRARPEVAPEGEPGAPDSRAGGDTALSG 1222
>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
sapiens]
Length = 1690
Score = 27.7 bits (60), Expect = 7.6
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVG 49
P PGK + +G+PGLPG++ + G
Sbjct: 725 PGLPGKDGLPGMIGSPGLPGSKGATG 750
>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
Length = 717
Score = 27.7 bits (60), Expect = 7.6
Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 6/31 (19%)
Query: 20 CVLEPRPPGKRWMVAGLGNPGLPGTRHSVGM 50
C P PPG G PGLPG + ++GM
Sbjct: 117 CNCPPGPPGPT------GRPGLPGDKGAIGM 141
>gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo
sapiens]
Length = 654
Score = 27.3 bits (59), Expect = 10.0
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 62 VAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAE 107
VAE DR AA A G + L RPRR + R VA AAE
Sbjct: 158 VAEQEREDRQAAA----AGPGTSGLAATRPRRWLQLWRRGVAEAAE 199
>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
Length = 1714
Score = 27.3 bits (59), Expect = 10.0
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 28 GKRWMVAGLGNPGLPGTRHSVG 49
G +V G G PG PG R SVG
Sbjct: 666 GSPGLVGGTGPPGFPGLRGSVG 687
>gi|38505218 putative acyl-CoA dehydrogenase [Homo sapiens]
Length = 780
Score = 27.3 bits (59), Expect = 10.0
Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 13/64 (20%)
Query: 28 GKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRLGVAESWTRDRHCAADLALAPLGDAQLV 87
GK+W +G GNP ++A LG ++ + RH + L P+ +
Sbjct: 534 GKKWWSSGAGNPKC-------------KIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVK 580
Query: 88 LLRP 91
++RP
Sbjct: 581 IIRP 584
>gi|118498339 EMI domain containing 2 [Homo sapiens]
Length = 439
Score = 27.3 bits (59), Expect = 10.0
Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 33/111 (29%)
Query: 24 PRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRLGVAESWTRDRHCAADLALAPLGD 83
P PPG R G PG PGT S G+A E T + P G+
Sbjct: 311 PGPPGPR------GPPGPPGTPGSQGLA-----------GERGT----------VGPSGE 343
Query: 84 AQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYL------VHDELDKPLG 128
+ + A G V + E + AE V + +HD L P G
Sbjct: 344 PGVKGEEGEKAATAEGEGVQQLREALKILAERVLILEHMIGIHDPLASPEG 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,300,154
Number of Sequences: 37866
Number of extensions: 444995
Number of successful extensions: 1973
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1682
Number of HSP's gapped (non-prelim): 311
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.