Guide to the Human Genome
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Search of human proteins with 50838795

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50838795 metastasis associated 1 family, member 3 [Homo
sapiens]
         (515 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]  1043   0.0  
gi|115527080 metastasis associated protein [Homo sapiens]             770   0.0  
gi|14141170 metastasis-associated protein 2 [Homo sapiens]            728   0.0  
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]         161   1e-39
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]         161   1e-39
gi|7661892 REST corepressor 1 [Homo sapiens]                           78   2e-14
gi|45267839 mesoderm induction early response 1, family member 2...    66   7e-11
gi|94721313 mesoderm induction early response 1, family member 3...    64   3e-10
gi|27734799 REST corepressor 2 [Homo sapiens]                          64   3e-10
gi|225735631 mesoderm induction early response 1 isoform g [Homo...    64   4e-10
gi|225735619 mesoderm induction early response 1 isoform i [Homo...    64   4e-10
gi|225735617 mesoderm induction early response 1 isoform h [Homo...    64   4e-10
gi|225735615 mesoderm induction early response 1 isoform a [Homo...    64   4e-10
gi|118130872 mesoderm induction early response 1 isoform f [Homo...    64   4e-10
gi|225735612 mesoderm induction early response 1 isoform e [Homo...    64   4e-10
gi|225735610 mesoderm induction early response 1 isoform d [Homo...    64   4e-10
gi|118130815 mesoderm induction early response 1 isoform c [Homo...    64   4e-10
gi|225735607 mesoderm induction early response 1 isoform b [Homo...    64   4e-10
gi|225735605 mesoderm induction early response 1 isoform a [Homo...    64   4e-10
gi|209977084 REST corepressor 3 isoform c [Homo sapiens]               63   7e-10
gi|209977082 REST corepressor 3 isoform b [Homo sapiens]               63   7e-10
gi|209977080 REST corepressor 3 isoform a [Homo sapiens]               63   7e-10
gi|8922733 REST corepressor 3 isoform d [Homo sapiens]                 63   7e-10
gi|15812226 transcriptional regulating factor 1 [Homo sapiens]         51   3e-06
gi|210031154 zinc finger protein 541 [Homo sapiens]                    43   6e-04
gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]           39   0.009
gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]           39   0.009
gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi...    39   0.009
gi|30794372 polybromo 1 isoform 1 [Homo sapiens]                       36   0.074
gi|41281917 polybromo 1 isoform 4 [Homo sapiens]                       36   0.074

>gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]
          Length = 515

 Score = 1043 bits (2696), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLAD 60
           MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLAD
Sbjct: 1   MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLAD 60

Query: 61  KHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESV 120
           KHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESV
Sbjct: 61  KHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESV 120

Query: 121 LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVK 180
           LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVK
Sbjct: 121 LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVK 180

Query: 181 VWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDT 240
           VWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDT
Sbjct: 181 VWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDT 240

Query: 241 LYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPW 300
           LYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPW
Sbjct: 241 LYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPW 300

Query: 301 KSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAV 360
           KSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAV
Sbjct: 301 KSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAV 360

Query: 361 NGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPT 420
           NGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPT
Sbjct: 361 NGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPT 420

Query: 421 QSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFAR 480
           QSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFAR
Sbjct: 421 QSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFAR 480

Query: 481 QVCKNTLRLRQAARRPFVAINYAAIRAECKMLLNS 515
           QVCKNTLRLRQAARRPFVAINYAAIRAECKMLLNS
Sbjct: 481 QVCKNTLRLRQAARRPFVAINYAAIRAECKMLLNS 515


>gi|115527080 metastasis associated protein [Homo sapiens]
          Length = 715

 Score =  770 bits (1988), Expect = 0.0
 Identities = 387/526 (73%), Positives = 431/526 (81%), Gaps = 31/526 (5%)

Query: 1   MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLAD 60
           MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTA+GNVEAKVVCFYRRRDIS+TLI LAD
Sbjct: 1   MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD 60

Query: 61  KHAK-----------------EIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPAT 103
           KHA                  EIEEE E     DL +K KHQL+HRELFLSRQ ESLPAT
Sbjct: 61  KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT 120

Query: 104 HIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEM 163
           HIRGKCSV LLNETES+ SYL++ED FFYSLVYDP  KTLLADKGEIRVG RYQADI ++
Sbjct: 121 HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL 180

Query: 164 LLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHM 223
           L EGE D R+QS+LE +VW+ ++PLTD+QIDQFLVVAR+VGTFARALDCSSSVRQPSLHM
Sbjct: 181 LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM 240

Query: 224 SAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEAL 283
           SAAAASRDITLFHAMDTL+++ YD+S AIS LVP GGPVLCRDEMEEWSASEA+LFEEAL
Sbjct: 241 SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL 300

Query: 284 EKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYS 343
           EKYGKDF DI+QDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIP Y+
Sbjct: 301 EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN 360

Query: 344 KPNPNQISTSNGKPGAVNGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLC 403
           KPNPNQIS +N K G VN   GT    Q+P  GRACESCY TQS+QWYSWGPPNMQCRLC
Sbjct: 361 KPNPNQISVNNVKAGVVN---GTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLC 417

Query: 404 AICWLYWKKYGGLKMPTQSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVK 463
           A CW YWKKYGGLKMPT+ + E+  P+ +   P            G+P R++GSPK A+K
Sbjct: 418 ASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSP-----------HGLPARSSGSPKFAMK 466

Query: 464 TRQAFFLHTTYFTKFARQVCKNTLRLRQAARRPFVAINYAAIRAEC 509
           TRQAF+LHTT  T+ AR++C+  LR   AAR P++ IN AAI+AEC
Sbjct: 467 TRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAEC 512


>gi|14141170 metastasis-associated protein 2 [Homo sapiens]
          Length = 668

 Score =  728 bits (1880), Expect = 0.0
 Identities = 364/515 (70%), Positives = 422/515 (81%), Gaps = 18/515 (3%)

Query: 1   MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLAD 60
           MAANMYRVGDYVYFENSSSNPYL+RRIEELNKTA+GNVEAKVVC +RRRDIS++L  LAD
Sbjct: 1   MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLAD 60

Query: 61  KHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESV 120
            +A+E EEES+   +  ++++Q+HQLKHRELFLSRQ+ESLPATHIRGKCSV LLNET+ +
Sbjct: 61  SNAREFEEESK---QPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDIL 117

Query: 121 LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVK 180
             YL+KED FFYSLV+DP  KTLLAD+GEIRVG +YQA+IP+ L+EGESD R Q K+E+K
Sbjct: 118 SQYLEKEDCFFYSLVFDPVQKTLLADQGEIRVGCKYQAEIPDRLVEGESDNRNQQKMEMK 177

Query: 181 VWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDT 240
           VWDP++PLTDRQIDQFLVVARAVGTFARALDCSSS+RQPSLHMSAAAASRDITLFHAMDT
Sbjct: 178 VWDPDNPLTDRQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDT 237

Query: 241 LYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPW 300
           L R+ YDL+ A+S LVP GGPVLCRDEMEEWSASEA LFEEALEKYGKDFNDIRQDFLPW
Sbjct: 238 LQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPW 297

Query: 301 KSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAV 360
           KSL SI+++YYMWKTTDRY+QQKRLKAAEA+SKLKQVYIPTY+KPNPNQI +   KPG +
Sbjct: 298 KSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISVGSKPG-M 356

Query: 361 NGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPT 420
           NGA    FQ      G  CESC+ TQS QWY+WGPPNMQCRLCA CW+YWKKYGGLK PT
Sbjct: 357 NGA---GFQK-----GLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPT 408

Query: 421 QSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGS--PKSAVKTRQAFFLHTTYFTKF 478
           Q E      +  T +P  R H+SR   Q +    T +   K   K RQ F L TT  T+ 
Sbjct: 409 QLE----GATRGTTEPHSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRL 464

Query: 479 ARQVCKNTLRLRQAARRPFVAINYAAIRAECKMLL 513
           AR++C++ L+ R+AARRP+  IN  AI+AEC + L
Sbjct: 465 ARRMCRDLLQPRRAARRPYAPINANAIKAECSIRL 499


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score =  161 bits (408), Expect = 1e-39
 Identities = 134/504 (26%), Positives = 226/504 (44%), Gaps = 90/504 (17%)

Query: 5   MYRVGDYVYFENSSSN-PYLIRRIEE---------------------------------- 29
           +YR GD VY E+   N PY I  I++                                  
Sbjct: 104 VYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPTPALCDPPACSLPVASQPPQ 163

Query: 30  -LNKTASGNVEAK-------VVCFYRRRDISNTLI--MLADKHAKEIEEESETTVEADLT 79
            L++   G V +K       V  +YR+ ++ +++   ++ D+H      E+++  E  +T
Sbjct: 164 HLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRH-----NENDSGRELVIT 218

Query: 80  DKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPS 139
           D     +K+RELF+S   ++  A  +RGKC+++  ++  +   +  + D+FFY L Y+P 
Sbjct: 219 DPV---IKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPE 275

Query: 140 LKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVV 199
            + L + +GEIRVGP +QA +P++      D    ++ E  VW P   + D  +  +L  
Sbjct: 276 TRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPG--VNDCDLLMYLRA 333

Query: 200 ARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLG 259
           AR++  FA   D  S+           AASRD T  +A++TL+   YD   A+  LV   
Sbjct: 334 ARSMAAFAGMCDGGST------EDGCVAASRDDTTLNALNTLHESGYDAGKALQRLVKKP 387

Query: 260 GPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
            P L     + W+  E   F + L +YGK+F  IR++ LP K    +I +YY WK T   
Sbjct: 388 VPKLIE---KCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEA 444

Query: 320 VQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGA----VNGAVGTTFQPQN--- 372
              +  +    ++  +++   T S P    ++T +  P +    ++ A    F  ++   
Sbjct: 445 ASSRAHRRHRRQAVFRRIKTRTASTP----VNTPSRPPSSEFLDLSSASEDDFDSEDSEQ 500

Query: 373 PLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLK-------------MP 419
            L G AC  C+ T S  W+  G  N+   LC  C +++KKYG L               P
Sbjct: 501 ELKGYACRHCFTTTSKDWHHGGRENI--LLCTDCRIHFKKYGELPPIEKPVDPPPFMFKP 558

Query: 420 TQSEEEKLSPSPTTEDPRVRSHVS 443
            + E++ LS   +    R R  +S
Sbjct: 559 VKEEDDGLSGKHSMRTRRSRGSMS 582


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score =  161 bits (408), Expect = 1e-39
 Identities = 134/504 (26%), Positives = 226/504 (44%), Gaps = 90/504 (17%)

Query: 5   MYRVGDYVYFENSSSN-PYLIRRIEE---------------------------------- 29
           +YR GD VY E+   N PY I  I++                                  
Sbjct: 104 VYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPTPALCDPPACSLPVASQPPQ 163

Query: 30  -LNKTASGNVEAK-------VVCFYRRRDISNTLI--MLADKHAKEIEEESETTVEADLT 79
            L++   G V +K       V  +YR+ ++ +++   ++ D+H      E+++  E  +T
Sbjct: 164 HLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRH-----NENDSGRELVIT 218

Query: 80  DKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPS 139
           D     +K+RELF+S   ++  A  +RGKC+++  ++  +   +  + D+FFY L Y+P 
Sbjct: 219 DPV---IKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPE 275

Query: 140 LKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVV 199
            + L + +GEIRVGP +QA +P++      D    ++ E  VW P   + D  +  +L  
Sbjct: 276 TRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPG--VNDCDLLMYLRA 333

Query: 200 ARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLG 259
           AR++  FA   D  S+           AASRD T  +A++TL+   YD   A+  LV   
Sbjct: 334 ARSMAAFAGMCDGGST------EDGCVAASRDDTTLNALNTLHESGYDAGKALQRLVKKP 387

Query: 260 GPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
            P L     + W+  E   F + L +YGK+F  IR++ LP K    +I +YY WK T   
Sbjct: 388 VPKLIE---KCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEA 444

Query: 320 VQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGA----VNGAVGTTFQPQN--- 372
              +  +    ++  +++   T S P    ++T +  P +    ++ A    F  ++   
Sbjct: 445 ASSRAHRRHRRQAVFRRIKTRTASTP----VNTPSRPPSSEFLDLSSASEDDFDSEDSEQ 500

Query: 373 PLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLK-------------MP 419
            L G AC  C+ T S  W+  G  N+   LC  C +++KKYG L               P
Sbjct: 501 ELKGYACRHCFTTTSKDWHHGGRENI--LLCTDCRIHFKKYGELPPIEKPVDPPPFMFKP 558

Query: 420 TQSEEEKLSPSPTTEDPRVRSHVS 443
            + E++ LS   +    R R  +S
Sbjct: 559 VKEEDDGLSGKHSMRTRRSRGSMS 582


>gi|7661892 REST corepressor 1 [Homo sapiens]
          Length = 482

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 45/199 (22%)

Query: 148 GEIRVGPRYQADIPEM---LLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVG 204
           G +RVGP+YQA +P+     L   S ER+   L + VW PN  L++ ++D+++ +A+   
Sbjct: 100 GGMRVGPQYQAVVPDFDPAKLARRSQERDN--LGMLVWSPNQNLSEAKLDEYIAIAKE-- 155

Query: 205 TFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLC 264
                                        +  A+  L+ H +++  +++ L P   P   
Sbjct: 156 ------------------------KHGYNMEQALGMLFWHKHNIEKSLADL-PNFTPF-- 188

Query: 265 RDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT-------D 317
               +EW+  +  LFE+A   +GK F+ I+Q  LP KS+ S++++YY WK T       D
Sbjct: 189 ---PDEWTVEDKVLFEQAFSFHGKTFHRIQQ-MLPDKSIASLVKFYYSWKKTRTKTSVMD 244

Query: 318 RYVQQKRLKAAEAESKLKQ 336
           R+ ++++ +  E+E +L++
Sbjct: 245 RHARKQKREREESEDELEE 263



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 271 WSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEA 330
           W+  E  L  +A+ KYG+DF  I  D +  KS+  +  ++  ++   R+   + L+  EA
Sbjct: 383 WTTEEQLLAVQAIRKYGRDFQAI-SDVIGNKSVVQVKNFFVNYRR--RFNIDEVLQEWEA 439

Query: 331 ESKLKQVYIPTYSKP 345
           E   ++   P+  KP
Sbjct: 440 EHGKEETNGPSNQKP 454


>gi|45267839 mesoderm induction early response 1, family member 2
           [Homo sapiens]
          Length = 545

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 62/237 (26%), Positives = 110/237 (46%), Gaps = 29/237 (12%)

Query: 147 KGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF 206
           K EI VGP++QAD+  + L    ++  +++ ++ +WDP S L +R++++FL   RAV   
Sbjct: 194 KKEIMVGPQFQADLSNLHLNRHCEKIYENEDQL-LWDP-SVLPEREVEEFLY--RAVKRR 249

Query: 207 ARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRD 266
              +        P L    A    +  L+     L + ++++  A+  L       + RD
Sbjct: 250 WHEM------AGPQLPEGEAVKDSEQALYE----LVKCNFNVEEALRRL--RFNVKVIRD 297

Query: 267 EMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRY---VQQK 323
            +  WS  E   FE     +GK+F+ I+ + +  +S+   +EYYY+WK ++RY    QQ 
Sbjct: 298 GLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQT 357

Query: 324 RL--------KAAEAESKLKQVYIPTYSKPNPNQ--ISTSNGKPGAVNGAVGTTFQP 370
           RL           +A+  L         +P P Q  ++     P +V+G  G   +P
Sbjct: 358 RLGRRKYVPSGTTDADQDLDGSDPDGPGRPRPEQDTLTGMRTDPLSVDGTAGGLDEP 414


>gi|94721313 mesoderm induction early response 1, family member 3
           [Homo sapiens]
          Length = 549

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 55/226 (24%), Positives = 102/226 (45%), Gaps = 25/226 (11%)

Query: 149 EIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFAR 208
           EI +G +YQA+IP  L E + +E+     +  +W P+  L + ++ ++LV         +
Sbjct: 175 EIMIGLQYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVL-ESKVKEYLVETSLRTGSEK 233

Query: 209 ALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEM 268
            +D           +SA   +RD     A+  L + ++++  AI      G        M
Sbjct: 234 IMD----------RISAGTHTRDNE--QALYELLKCNHNIKEAIERYCCNGK---ASQGM 278

Query: 269 EEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRY---VQQKRL 325
             W+  E   FE AL  +GKDF+ I+++ +  +++   + +YYMWK ++RY    QQ R 
Sbjct: 279 TAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRF 338

Query: 326 KAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAVNGAVGTTFQPQ 371
                  K +  + P  +      +  +    G VN +  T+ +P+
Sbjct: 339 ------GKKRYNHHPGVTDYMDRLVDETEALGGTVNASALTSNRPE 378


>gi|27734799 REST corepressor 2 [Homo sapiens]
          Length = 523

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 33/167 (19%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           IRVG  YQA IPE   E  +    +    + VW PN  ++D ++D+++ +A+        
Sbjct: 46  IRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKE------- 98

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
                                   +  A+  L  H +D+  +++ L             +
Sbjct: 99  -------------------KHGYNIEQALGMLLWHKHDVEKSLADLANF------TPFPD 133

Query: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           EW+  +  LFE+A   +GK F  I+Q  LP K + S+++YYY WK T
Sbjct: 134 EWTVEDKVLFEQAFGFHGKCFQRIQQ-MLPDKLIPSLVKYYYSWKKT 179



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 257 PLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           PL  P         W+  E  L  +A+ +YGKDF  I  + +  K+LT +  ++  ++  
Sbjct: 318 PLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAI-AEVIGNKTLTQVKTFFVSYRR- 375

Query: 317 DRYVQQKRLKAAEAE 331
            R+  ++ L+  EAE
Sbjct: 376 -RFNLEEVLQEWEAE 389


>gi|225735631 mesoderm induction early response 1 isoform g [Homo
           sapiens]
          Length = 470

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 102 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 161

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 162 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 221

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 222 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 281

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 282 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 324

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 325 HLIQANKVRTRSVGECVAFYYMWKKSERY 353


>gi|225735619 mesoderm induction early response 1 isoform i [Homo
           sapiens]
          Length = 370

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 22  DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 81

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 82  QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 141

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 142 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 201

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 202 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 244

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 245 HLIQANKVRTRSVGECVAFYYMWKKSERY 273


>gi|225735617 mesoderm induction early response 1 isoform h [Homo
           sapiens]
          Length = 485

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 58  DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 117

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 118 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 177

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 178 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 237

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 238 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 280

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 281 HLIQANKVRTRSVGECVAFYYMWKKSERY 309


>gi|225735615 mesoderm induction early response 1 isoform a [Homo
           sapiens]
          Length = 529

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 102 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 161

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 162 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 221

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 222 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 281

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 282 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 324

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 325 HLIQANKVRTRSVGECVAFYYMWKKSERY 353


>gi|118130872 mesoderm induction early response 1 isoform f [Homo
           sapiens]
          Length = 433

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 85  DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 144

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 145 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 204

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 205 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 264

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 265 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 307

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 308 HLIQANKVRTRSVGECVAFYYMWKKSERY 336


>gi|225735612 mesoderm induction early response 1 isoform e [Homo
           sapiens]
          Length = 486

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 138 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 197

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 198 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 257

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 258 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 317

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 318 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 360

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 361 HLIQANKVRTRSVGECVAFYYMWKKSERY 389


>gi|225735610 mesoderm induction early response 1 isoform d [Homo
           sapiens]
          Length = 450

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 102 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 161

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 162 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 221

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 222 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 281

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 282 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 324

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 325 HLIQANKVRTRSVGECVAFYYMWKKSERY 353


>gi|118130815 mesoderm induction early response 1 isoform c [Homo
           sapiens]
          Length = 512

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 85  DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 144

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 145 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 204

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 205 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 264

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 265 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 307

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 308 HLIQANKVRTRSVGECVAFYYMWKKSERY 336


>gi|225735607 mesoderm induction early response 1 isoform b [Homo
           sapiens]
          Length = 565

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 138 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 197

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 198 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 257

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 258 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 317

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 318 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 360

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 361 HLIQANKVRTRSVGECVAFYYMWKKSERY 389


>gi|225735605 mesoderm induction early response 1 isoform a [Homo
           sapiens]
          Length = 529

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 63/269 (23%), Positives = 110/269 (40%), Gaps = 26/269 (9%)

Query: 60  DKHAKEIEEESETTVEADLTDKQKHQLKHRELFL---SRQYESLPATHIRGKCSVALLNE 116
           D+  +E EEE E   +AD  D      +++E  +   S Q +   +++     SVA  + 
Sbjct: 102 DEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDA 161

Query: 117 TESV----LSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDER 172
            E +      Y D           D         K EI VG  +QA+IP  +   + +E+
Sbjct: 162 QEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEK 221

Query: 173 EQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTF--ARALDCSSSVRQPSLHMSAAAASR 230
                +  +WDP     D+ I      +R  G      A+   S ++     +       
Sbjct: 222 VYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCN 281

Query: 231 DITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDF 290
               F   + L R  +++ +A             R+E+  W+  E   FE+ L+ YGKDF
Sbjct: 282 ----FDTEEALRRLRFNVKAA-------------REELSVWTEEECRNFEQGLKAYGKDF 324

Query: 291 NDIRQDFLPWKSLTSIIEYYYMWKTTDRY 319
           + I+ + +  +S+   + +YYMWK ++RY
Sbjct: 325 HLIQANKVRTRSVGECVAFYYMWKKSERY 353


>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
          Length = 449

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           +RVG  YQA IPE    G +   ++    + VW P   + D ++D+++ +A+    +   
Sbjct: 59  MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
                +V Q                  A+  L+ H +++  +++ L P   P       +
Sbjct: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145

Query: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           EW+  +  LFE+A   +GK F+ I+Q  LP K++ S+++YYY WK T
Sbjct: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191


>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
          Length = 436

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           +RVG  YQA IPE    G +   ++    + VW P   + D ++D+++ +A+    +   
Sbjct: 59  MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDARLDEYIAIAKEKHGY--- 114

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
                +V Q                  A+  L+ H +++  +++ L P   P       +
Sbjct: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145

Query: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           EW+  +  LFE+A   +GK F+ I+Q  LP K++ S+++YYY WK T
Sbjct: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191


>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
          Length = 553

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           +RVG  YQA IPE    G +   ++    + VW P   + D ++D+++ +A+    +   
Sbjct: 59  MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
                +V Q                  A+  L+ H +++  +++ L P   P       +
Sbjct: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145

Query: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           EW+  +  LFE+A   +GK F+ I+Q  LP K++ S+++YYY WK T
Sbjct: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191


>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
          Length = 495

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           +RVG  YQA IPE    G +   ++    + VW P   + D ++D+++ +A+    +   
Sbjct: 1   MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 56

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
                +V Q                  A+  L+ H +++  +++ L P   P       +
Sbjct: 57  -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 87

Query: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
           EW+  +  LFE+A   +GK F+ I+Q  LP K++ S+++YYY WK T
Sbjct: 88  EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 133


>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
          Length = 1200

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 31/189 (16%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
           I +G R+QA+IPE  L+  S   + +     VW P   L +  + Q +            
Sbjct: 781 INIGLRFQAEIPE--LQDISALAQDTHKATLVWKPWPELENHDLQQRV-------ENLLN 831

Query: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDE-- 267
           L CSS++     +              A+ +L+    D+  A+ +L+ L  PV  +    
Sbjct: 832 LCCSSALPGGGTNSE-----------FALHSLFEAKGDVMVALEMLL-LRKPVRLKCHPL 879

Query: 268 -------MEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYV 320
                   ++W++ E  LF +AL  Y KDF  + Q  +  K++   +EYYY WK   R  
Sbjct: 880 ANYHYAGSDKWTSLERKLFNKALATYSKDFIFV-QKMVKSKTVAQCVEYYYTWKKIMRLG 938

Query: 321 QQKRLKAAE 329
           ++ R + AE
Sbjct: 939 RKHRTRLAE 947


>gi|210031154 zinc finger protein 541 [Homo sapiens]
          Length = 1365

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 57/253 (22%), Positives = 101/253 (39%), Gaps = 48/253 (18%)

Query: 120  VLSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEV 179
            + S LD+ D  F   V     K  ++ +  I +G R+QA+IPE  L+  S       +  
Sbjct: 1046 ISSMLDQVDGSFGICVVKDDTK--ISIEPHINIGSRFQAEIPE--LQERSLAGTDEHVAS 1101

Query: 180  KVWDPNSPL-----TDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITL 234
             VW P   +     T  ++ +   VA           CSS +     ++  A        
Sbjct: 1102 LVWKPWGDMMISSETQDRVTELCNVA-----------CSSVMPGGGTNLELA-------- 1142

Query: 235  FHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEM---------EEWSASEASLFEEALEK 285
               +  L+    ++  A+  L+ L GP   R  +         + W+  E  LF++A   
Sbjct: 1143 ---LHCLHEAQGNVQVALETLL-LRGPHKPRTHLLADYRYTGSDVWTPIEKRLFKKAFYA 1198

Query: 286  YGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRY------VQQKRLKAAEAESKLKQVYI 339
            + KDF  I +  +  K++   +EYYY+WK   ++        +KR+K    E +  +  +
Sbjct: 1199 HKKDFYLIHK-MIQTKTVAQCVEYYYIWKKMIKFDCGRAPGLEKRVKREPEEVERTEEKV 1257

Query: 340  PTYSKPNPNQIST 352
            P   +  P+   T
Sbjct: 1258 PCSPRERPSHHPT 1270


>gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 19/51 (37%), Positives = 30/51 (58%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVA 200
           +RVG  YQA IPE   E  +    +    V VW PN  ++D ++D+++V+A
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMA 52


>gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 19/51 (37%), Positives = 30/51 (58%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVA 200
           +RVG  YQA IPE   E  +    +    V VW PN  ++D ++D+++V+A
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMA 52


>gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo
           sapiens]
          Length = 266

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 19/51 (37%), Positives = 30/51 (58%)

Query: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVA 200
           +RVG  YQA IPE   E  +    +    V VW PN  ++D ++D+++V+A
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMA 52


>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
          Length = 1602

 Score = 36.2 bits (82), Expect = 0.074
 Identities = 33/115 (28%), Positives = 48/115 (41%), Gaps = 30/115 (26%)

Query: 4    NMYRVGDYVYFENSSSN--PYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADK 61
            +MY VGDYVY E + +N  P+++  IE L + ++G        FYR     N    LA +
Sbjct: 924  SMYHVGDYVYVEPAEANLQPHIV-CIERLWEDSAGEKWLYGCWFYR----PNETFHLATR 978

Query: 62   HAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNE 116
               E                       +E+F S  Y  +P + I GKC V  + E
Sbjct: 979  KFLE-----------------------KEVFKSDYYNKVPVSKILGKCVVMFVKE 1010


>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
          Length = 1582

 Score = 36.2 bits (82), Expect = 0.074
 Identities = 33/115 (28%), Positives = 48/115 (41%), Gaps = 30/115 (26%)

Query: 4    NMYRVGDYVYFENSSSN--PYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADK 61
            +MY VGDYVY E + +N  P+++  IE L + ++G        FYR     N    LA +
Sbjct: 956  SMYHVGDYVYVEPAEANLQPHIV-CIERLWEDSAGEKWLYGCWFYR----PNETFHLATR 1010

Query: 62   HAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNE 116
               E                       +E+F S  Y  +P + I GKC V  + E
Sbjct: 1011 KFLE-----------------------KEVFKSDYYNKVPVSKILGKCVVMFVKE 1042


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,603,743
Number of Sequences: 37866
Number of extensions: 890535
Number of successful extensions: 2935
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2835
Number of HSP's gapped (non-prelim): 92
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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