Guide to the Human Genome
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Search of human proteins with 50659082

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50659082 suppressor of variegation 4-20 homolog 1 isoform 1
[Homo sapiens]
         (885 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50659082 suppressor of variegation 4-20 homolog 1 isoform 1 [...  1790   0.0  
gi|50659084 suppressor of variegation 4-20 homolog 1 isoform 2 [...   809   0.0  
gi|31543169 suppressor of variegation 4-20 homolog 2 [Homo sapiens]   341   2e-93
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    52   2e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    52   2e-06
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    46   2e-04
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    46   2e-04
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    46   2e-04
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    46   2e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    44   9e-04
gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]    44   9e-04
gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]    44   9e-04
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]          42   0.003
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  42   0.003
gi|148612801 KIAA1009 protein [Homo sapiens]                           42   0.003
gi|12232401 SET and MYND domain containing 3 [Homo sapiens]            40   0.007
gi|68508961 centromere protein C 1 [Homo sapiens]                      40   0.007
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          40   0.007
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]     40   0.013
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]     40   0.013
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    40   0.013
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    40   0.013
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.016
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.016
gi|39725952 angiogenic factor VG5Q [Homo sapiens]                      39   0.021
gi|54633315 deoxynucleotidyltransferase, terminal, interacting p...    39   0.028
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    39   0.028
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    39   0.028
gi|23957698 luman-recruiting factor [Homo sapiens]                     38   0.036
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           38   0.036

>gi|50659082 suppressor of variegation 4-20 homolog 1 isoform 1
           [Homo sapiens]
          Length = 885

 Score = 1790 bits (4636), Expect = 0.0
 Identities = 885/885 (100%), Positives = 885/885 (100%)

Query: 1   MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 60
           MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF
Sbjct: 1   MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 60

Query: 61  EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 120
           EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS
Sbjct: 61  EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 120

Query: 121 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 180
           HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE
Sbjct: 121 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 180

Query: 181 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 240
           HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN
Sbjct: 181 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 240

Query: 241 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 300
           MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG
Sbjct: 241 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 300

Query: 301 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 360
           EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR
Sbjct: 301 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 360

Query: 361 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 420
           LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA
Sbjct: 361 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 420

Query: 421 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 480
           SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP
Sbjct: 421 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 480

Query: 481 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 540
           KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR
Sbjct: 481 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 540

Query: 541 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 600
           SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA
Sbjct: 541 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 600

Query: 601 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 660
           KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG
Sbjct: 601 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 660

Query: 661 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 720
           VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL
Sbjct: 661 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 720

Query: 721 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 780
           RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ
Sbjct: 721 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 780

Query: 781 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 840
           LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD
Sbjct: 781 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 840

Query: 841 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 885
           YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA
Sbjct: 841 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 885


>gi|50659084 suppressor of variegation 4-20 homolog 1 isoform 2
           [Homo sapiens]
          Length = 393

 Score =  809 bits (2090), Expect = 0.0
 Identities = 391/392 (99%), Positives = 392/392 (100%)

Query: 1   MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 60
           MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF
Sbjct: 1   MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 60

Query: 61  EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 120
           EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS
Sbjct: 61  EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 120

Query: 121 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 180
           HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE
Sbjct: 121 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 180

Query: 181 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 240
           HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN
Sbjct: 181 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 240

Query: 241 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 300
           MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG
Sbjct: 241 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 300

Query: 301 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 360
           EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR
Sbjct: 301 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 360

Query: 361 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNAT 392
           LKKLGDSSKNSDSQSVSSNTDADTTQEKNNA+
Sbjct: 361 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNAS 392


>gi|31543169 suppressor of variegation 4-20 homolog 2 [Homo sapiens]
          Length = 462

 Score =  341 bits (874), Expect = 2e-93
 Identities = 168/289 (58%), Positives = 203/289 (70%), Gaps = 24/289 (8%)

Query: 72  MSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFSHNNPVRFRPIK 131
           ++A+ELCENDDLATSLVLDPYLGF+THKMN S  P                 P+R     
Sbjct: 6   VTARELCENDDLATSLVLDPYLGFRTHKMNVSPVP-----------------PLR----- 43

Query: 132 GRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFAT 191
            RQ+ L+  +E F +   LE A++ LT G W   YF ++   QE   K HV+ YLR F  
Sbjct: 44  -RQQHLRSALETFLRQRDLEAAYRALTLGGWTARYFQSRGPRQEAALKTHVYRYLRAFLP 102

Query: 192 DSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFS 251
           +SGF ILPC RYS E NGAKIV+T+ WK+N+K+ELLVGCIAEL E +E  LLR GENDFS
Sbjct: 103 ESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVGCIAELREADEG-LLRAGENDFS 161

Query: 252 VMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGF 311
           +MYSTRK  AQLWLGPAAFINHDC+PNCKFV    + ACVK LRDIEPG+E++C+YG+GF
Sbjct: 162 IMYSTRKRSAQLWLGPAAFINHDCKPNCKFVPADGNAACVKVLRDIEPGDEVTCFYGEGF 221

Query: 312 FGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 360
           FGE NE CEC+TCER+G GAF++R   PA  P    KY LRET +RL +
Sbjct: 222 FGEKNEHCECHTCERKGEGAFRTRPREPALPPRPLDKYQLRETKRRLQQ 270



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 849 FIPLPPAKRLRLIVGKDSIDIDI 871
           F P  P KRLRL+V   SID+D+
Sbjct: 435 FAPFSPPKRLRLVVSHGSIDLDV 457


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 112/537 (20%), Positives = 202/537 (37%), Gaps = 106/537 (19%)

Query: 386  QEKNNATSNRKSSVGVK-KNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKP 444
            Q KN  T   K S  ++ K SK +        +     +S  S     + +    + KK 
Sbjct: 996  QIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1055

Query: 445  AKPLLSKIKLRNHCKRLEQKNASRKLEMGNLV---LKEPKVVLYKNLPIKKD-KEPEGPA 500
             K L    + R  C   + +  S K +  N     LK  ++   +NL  K++ KE +  +
Sbjct: 1056 CKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGS 1115

Query: 501  QAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEA-------SD 553
             ++ A      +  ++ R +  + A    E        R S+RT T  K+A       SD
Sbjct: 1116 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK------RNSLRTSTKRKQADITSSSSSD 1169

Query: 554  I----------------KLEPNTLNGYKSSVTEPCPDSGEQL--QPAPVLQEEELAHETA 595
            I                K++P T N   SS T  C  SG++   +  PV  +++      
Sbjct: 1170 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1229

Query: 596  QKGEAK----------CHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDL 645
            +   AK              + G S  +  +GK  K+  K  E     ++PG ++A    
Sbjct: 1230 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGK--KRTGKQNE-----ENPGDEEAK--- 1279

Query: 646  MGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDA 705
                                          + V S+S    DS  + K + + R+ R+  
Sbjct: 1280 ------------------------------NQVNSES--DSDSEESKKPRYRHRLLRHKL 1307

Query: 706  QLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNG 765
              + +  SG  K T  + H        +E  G N  K+S + S+D D   +    +++  
Sbjct: 1308 T-VSDGESGEEKKTKPKEH--------KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358

Query: 766  FNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEES 825
             +     + +  K +L   EEN+ SY +      +   +     +S  E    S+ EEE 
Sbjct: 1359 EDEQRPRTRSAKKAEL---EENQRSYKQKKKRRRIKVQE-----DSSSENKSNSEEEEEE 1410

Query: 826  TDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLR 882
             ++    E +EEE++ +D+ +D   P    K++R I+  D +  +  +  +E++  R
Sbjct: 1411 KEEEEEEE-EEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERR 1466


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 112/537 (20%), Positives = 202/537 (37%), Gaps = 106/537 (19%)

Query: 386  QEKNNATSNRKSSVGVK-KNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKP 444
            Q KN  T   K S  ++ K SK +        +     +S  S     + +    + KK 
Sbjct: 1034 QIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1093

Query: 445  AKPLLSKIKLRNHCKRLEQKNASRKLEMGNLV---LKEPKVVLYKNLPIKKD-KEPEGPA 500
             K L    + R  C   + +  S K +  N     LK  ++   +NL  K++ KE +  +
Sbjct: 1094 CKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGS 1153

Query: 501  QAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEA-------SD 553
             ++ A      +  ++ R +  + A    E        R S+RT T  K+A       SD
Sbjct: 1154 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK------RNSLRTSTKRKQADITSSSSSD 1207

Query: 554  I----------------KLEPNTLNGYKSSVTEPCPDSGEQL--QPAPVLQEEELAHETA 595
            I                K++P T N   SS T  C  SG++   +  PV  +++      
Sbjct: 1208 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1267

Query: 596  QKGEAK----------CHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDL 645
            +   AK              + G S  +  +GK  K+  K  E     ++PG ++A    
Sbjct: 1268 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGK--KRTGKQNE-----ENPGDEEAK--- 1317

Query: 646  MGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDA 705
                                          + V S+S    DS  + K + + R+ R+  
Sbjct: 1318 ------------------------------NQVNSES--DSDSEESKKPRYRHRLLRHKL 1345

Query: 706  QLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNG 765
              + +  SG  K T  + H        +E  G N  K+S + S+D D   +    +++  
Sbjct: 1346 T-VSDGESGEEKKTKPKEH--------KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1396

Query: 766  FNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEES 825
             +     + +  K +L   EEN+ SY +      +   +     +S  E    S+ EEE 
Sbjct: 1397 EDEQRPRTRSAKKAEL---EENQRSYKQKKKRRRIKVQE-----DSSSENKSNSEEEEEE 1448

Query: 826  TDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLR 882
             ++    E +EEE++ +D+ +D   P    K++R I+  D +  +  +  +E++  R
Sbjct: 1449 KEEEEEEE-EEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERR 1504


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 20/181 (11%)

Query: 205  SEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENML-LRHG-ENDFSVMYS-TRKNCA 261
            ++  G  +VA ++ ++ + +   VG   EL + EE M  ++H  END +  Y  T     
Sbjct: 1070 TDGKGWGLVAKRDIRKGEFVNEYVG---ELIDEEECMARIKHAHENDITHFYMLTIDKDR 1126

Query: 262  QLWLGP----AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGE 314
             +  GP    + F+NH C+PNC   K+   G     + A+ DI  G E++  Y     G 
Sbjct: 1127 IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGN 1186

Query: 315  NNEFCECYTCERRGTGAFKSRVG-LPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDS 373
                C C      G       +G  P  +  ++S+   ++T K+  R +  G+  + S+ 
Sbjct: 1187 EKTVCRC------GASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSED 1240

Query: 374  Q 374
            +
Sbjct: 1241 E 1241


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 20/181 (11%)

Query: 205  SEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENML-LRHG-ENDFSVMYS-TRKNCA 261
            ++  G  +VA ++ ++ + +   VG   EL + EE M  ++H  END +  Y  T     
Sbjct: 1070 TDGKGWGLVAKRDIRKGEFVNEYVG---ELIDEEECMARIKHAHENDITHFYMLTIDKDR 1126

Query: 262  QLWLGP----AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGE 314
             +  GP    + F+NH C+PNC   K+   G     + A+ DI  G E++  Y     G 
Sbjct: 1127 IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGN 1186

Query: 315  NNEFCECYTCERRGTGAFKSRVG-LPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDS 373
                C C      G       +G  P  +  ++S+   ++T K+  R +  G+  + S+ 
Sbjct: 1187 EKTVCRC------GASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSED 1240

Query: 374  Q 374
            +
Sbjct: 1241 E 1241


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 20/181 (11%)

Query: 205  SEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENML-LRHG-ENDFSVMYS-TRKNCA 261
            ++  G  +VA ++ ++ + +   VG   EL + EE M  ++H  END +  Y  T     
Sbjct: 1070 TDGKGWGLVAKRDIRKGEFVNEYVG---ELIDEEECMARIKHAHENDITHFYMLTIDKDR 1126

Query: 262  QLWLGP----AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGE 314
             +  GP    + F+NH C+PNC   K+   G     + A+ DI  G E++  Y     G 
Sbjct: 1127 IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGN 1186

Query: 315  NNEFCECYTCERRGTGAFKSRVG-LPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDS 373
                C C      G       +G  P  +  ++S+   ++T K+  R +  G+  + S+ 
Sbjct: 1187 EKTVCRC------GASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSED 1240

Query: 374  Q 374
            +
Sbjct: 1241 E 1241


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 20/181 (11%)

Query: 205  SEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENML-LRHG-ENDFSVMYS-TRKNCA 261
            ++  G  +VA ++ ++ + +   VG   EL + EE M  ++H  END +  Y  T     
Sbjct: 1070 TDGKGWGLVAKRDIRKGEFVNEYVG---ELIDEEECMARIKHAHENDITHFYMLTIDKDR 1126

Query: 262  QLWLGP----AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGE 314
             +  GP    + F+NH C+PNC   K+   G     + A+ DI  G E++  Y     G 
Sbjct: 1127 IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGN 1186

Query: 315  NNEFCECYTCERRGTGAFKSRVG-LPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDS 373
                C C      G       +G  P  +  ++S+   ++T K+  R +  G+  + S+ 
Sbjct: 1187 EKTVCRC------GASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSED 1240

Query: 374  Q 374
            +
Sbjct: 1241 E 1241


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 78/478 (16%), Positives = 156/478 (32%), Gaps = 25/478 (5%)

Query: 366  DSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNST 425
            DSS +SDS S  SN+ +D+    ++++ +  S      NS   + +  S     +S +S 
Sbjct: 562  DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 621

Query: 426  SSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLY 485
            S   +  + S       K      +     ++    +  N+S   +  +           
Sbjct: 622  SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD----------- 670

Query: 486  KNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTR 545
                   D      +  +  S   +  +   +       + S    S  +  +  S  + 
Sbjct: 671  -----SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 546  TNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKS 605
            ++   +SD     N+ +   SS +    DS +    +      + +  +     +    S
Sbjct: 726  SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 606  DTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSY 665
            +   +   S         +   +S+   DS   D +        SD  + S +     S 
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS- 844

Query: 666  TDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHD 725
            +D +      S   SDS  + DS  ++ S      +         N+S     +     D
Sbjct: 845  SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904

Query: 726  SSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDE 785
            SS  +N  ++   ++S  S + S   DN N+   +  ++  +S   S+S+        D 
Sbjct: 905  SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS--------DS 956

Query: 786  ENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDD 843
             N    +     +    SD      S    D     +   + DSS+S    +  D  D
Sbjct: 957  SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 83/486 (17%), Positives = 166/486 (34%), Gaps = 25/486 (5%)

Query: 366  DSSKNSDSQSVSSNTDA----DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPAS 421
            DSS +SDS   S+++D+    D++   ++ +SNR  S     +S S   +  S S   + 
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 422  SNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPK 481
            SN +S+     ++S         +          N     +  N+S   E  N       
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSS---------NSSDSSDSSNSSDSSESSNSSDNSNS 935

Query: 482  VVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRS 541
                 +       +    + ++ +S       + +   +    + +  +SS  +  +  S
Sbjct: 936  SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 542  VRT-RTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 600
              +  +N  ++SD     ++ N   SS +    +S +    +      + +  +     +
Sbjct: 996  DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 601  KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 660
                S        S         +   ES+   DS    D+        SD  + S +  
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS-----SDSSDSSDSSDSSD 1110

Query: 661  VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 720
               S      S    S  +SDS  + DS  ++ S      +  D+    +++        
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS--DSSDSSDSSDSSDSSDS 1168

Query: 721  RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 780
                DSS  +N  ++   + S  S   S   D+ ++   +  ++  +S   S S+     
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228

Query: 781  LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 840
               +E +  S +    ++    S+     +S    D  S   +ES   S S  G+    D
Sbjct: 1229 SDSNESSDSSDSSDSSDS----SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSD 1284

Query: 841  YDDDFE 846
             D D E
Sbjct: 1285 SDSDSE 1290



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 88/495 (17%), Positives = 162/495 (32%), Gaps = 36/495 (7%)

Query: 366  DSSKN----SDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPAS 421
            DSSK+    SDS S S ++D++++   +N+ S+  S+     +S   + +  S S   +S
Sbjct: 625  DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 422  SNSTSSKLTHINNSRVPKKLK--KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKE 479
            ++S SS  +  +NS           +    S     ++    +  N+S   +  N     
Sbjct: 685  NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744

Query: 480  PKVVLYKNLPIKKDKEPEGPAQAAVASGCL-TRHAAREHRQNPVRGAHSQGESSPCTYIT 538
                   +       +    + ++ +S    +  ++     N    +    +SS  +  +
Sbjct: 745  DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 539  RRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKG 598
              S  + ++    SD     ++ N   SS +    DS +    +     +      +   
Sbjct: 805  NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 599  EAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGT 658
                  SD+  S   S      +       S+   DS    D+        SD  + S +
Sbjct: 865  SDSSDSSDSSNSSDSSDSSDSNES----SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 659  VGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKL 718
                 S      S    S  +SDS  + DS  ++ S                +NS     
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD----------SSNSS---- 966

Query: 719  TLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLK 778
                  DSS   +   +D  NSS  S        +D++      ++  +S S  SS    
Sbjct: 967  ------DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020

Query: 779  IQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEE-----ESTDDSSSSE 833
                 D  N    ++    +    S   S         D S   +     +S+D S SS+
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 834  GDEEEDDYDDDFEDD 848
              E  D  D     D
Sbjct: 1081 SSESSDSSDSSNSSD 1095



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 59/278 (21%), Positives = 101/278 (36%), Gaps = 59/278 (21%)

Query: 574 DSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSR---QGKLVKQFAKIEEST 630
           D G +++  P      +  E  +  E K  K   GM   K     QG++V          
Sbjct: 373 DKGIEIK-GPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNI-------- 423

Query: 631 PVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFR 690
              + PG+     + +G HS+ G  S + G   SY     S  G    +SD     D   
Sbjct: 424 ---EGPGQKSEPGNKVG-HSNTGSDSNSDGYD-SYDFDDKSMQGDDPNSSDESNGND--- 475

Query: 691 TAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKD 750
                        DA    +NNS             +S  +D+  D  N S      SK 
Sbjct: 476 -------------DANSESDNNSS--------SRGDASYNSDESKDNGNGSD-----SKG 509

Query: 751 HDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLE 810
            ++D++   +  NN  ++G+G++          D+ ++    +G  ++    S      +
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNG--------NDDNDKSDSGKGKSDSSDSDSS-----D 556

Query: 811 SRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDD 848
           S    D     + +S+D +SSS+ D  + D  D  + D
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 9/78 (11%)

Query: 359 NRLKKLGDSSKNSDSQSVSSN---------TDADTTQEKNNATSNRKSSVGVKKNSKSRT 409
           N     GD+S NSD    + N          D+D+T + NN+ SN   + G   N KS +
Sbjct: 483 NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542

Query: 410 LTRQSMSRIPASSNSTSS 427
              +S S    SS+S++S
Sbjct: 543 GKGKSDSSDSDSSDSSNS 560



 Score = 33.9 bits (76), Expect = 0.69
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 2/124 (1%)

Query: 725 DSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRD 784
           DS S  +   +D  +SS  S        +D+    +K  +  +S S S S          
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD-SSDSDSKSDSSDSNSSDS 650

Query: 785 EENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEE-ESTDDSSSSEGDEEEDDYDD 843
            +N  S       N    SD     +S    D  +  +  +S+D S+SSE  +  D  D 
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710

Query: 844 DFED 847
           D  D
Sbjct: 711 DSSD 714



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 50/247 (20%), Positives = 82/247 (33%), Gaps = 30/247 (12%)

Query: 604 KSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPV 663
           KSD+G  K  S               +   DS    D+        SD    S +     
Sbjct: 539 KSDSGKGKSDS-------------SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585

Query: 664 SYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRR 723
             +D + S    S  +SDS  + DS  ++ S          ++   +++    K      
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645

Query: 724 HDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKR 783
           + S S  N   +D  NSS      S D  + ++          +S S SSS         
Sbjct: 646 NSSDSSDNSDSSDSSNSSN-----SSDSSDSSD----------SSDSSSSSDSSNSSDSS 690

Query: 784 DEENRGSYTEGLHENGVCCSDPLSLLES--RMEVDDYSQYEEESTDDSSSSEGDEEEDDY 841
           D  +  + +E    +    SD     +S      D  S    +S+D S+SS+  +  D  
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750

Query: 842 DDDFEDD 848
           +     D
Sbjct: 751 NSSDSSD 757



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 20/82 (24%), Positives = 37/82 (45%)

Query: 346  NSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNS 405
            NS      +D   +      DSS +SDS   S ++D+  + + +N++ +  SS     ++
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 406  KSRTLTRQSMSRIPASSNSTSS 427
             S +      S    SS+S+ S
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDS 1039


>gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]
          Length = 1173

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 71/334 (21%), Positives = 123/334 (36%), Gaps = 34/334 (10%)

Query: 353 ETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTR 412
           + ++R+N      ++S  S   S+         Q K N     K+++   +N        
Sbjct: 256 QMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRS 315

Query: 413 QSMSRIPASSNSTSSKLTHINN-SRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLE 471
            S S  P S+ S  +K       + V   LK   + ++ K +     KR +  +   K  
Sbjct: 316 SSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKF- 374

Query: 472 MGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVA---SGCLTRHAAREHRQNPVRGAHSQ 528
           + ++ LK P  VL      K+  +    + A +A   SG    H+ R   Q  V G    
Sbjct: 375 IKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKET 434

Query: 529 GESSPCTYITRR--SVRTRTNL---KEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPA- 582
               P   +++   +++  +NL   K AS    E  T    K  +    P +G  L P  
Sbjct: 435 KMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKET----KLPLLSRVPSAGSSLVPLN 490

Query: 583 ------PVLQEE-------ELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEES 629
                 PV +++       E +  + +  + K HK+ T  +      GK+     + E  
Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYG 550

Query: 630 TPVHDSPGKDDAVPDLMGPHS------DQGEHSG 657
           TP    P   + VP +  P +       +GE SG
Sbjct: 551 TPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSG 584


>gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]
          Length = 1186

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 71/334 (21%), Positives = 123/334 (36%), Gaps = 34/334 (10%)

Query: 353 ETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTR 412
           + ++R+N      ++S  S   S+         Q K N     K+++   +N        
Sbjct: 256 QMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRS 315

Query: 413 QSMSRIPASSNSTSSKLTHINN-SRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLE 471
            S S  P S+ S  +K       + V   LK   + ++ K +     KR +  +   K  
Sbjct: 316 SSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKF- 374

Query: 472 MGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVA---SGCLTRHAAREHRQNPVRGAHSQ 528
           + ++ LK P  VL      K+  +    + A +A   SG    H+ R   Q  V G    
Sbjct: 375 IKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKET 434

Query: 529 GESSPCTYITRR--SVRTRTNL---KEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPA- 582
               P   +++   +++  +NL   K AS    E  T    K  +    P +G  L P  
Sbjct: 435 KMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKET----KLPLLSRVPSAGSSLVPLN 490

Query: 583 ------PVLQEE-------ELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEES 629
                 PV +++       E +  + +  + K HK+ T  +      GK+     + E  
Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYG 550

Query: 630 TPVHDSPGKDDAVPDLMGPHS------DQGEHSG 657
           TP    P   + VP +  P +       +GE SG
Sbjct: 551 TPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSG 584


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 44/146 (30%), Positives = 67/146 (45%), Gaps = 12/146 (8%)

Query: 268  AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYG-DGFFGENNEFCECYT 323
            A FINH C PNC   K+   G     + AL+D+  G E++  Y    F  E  + C+C  
Sbjct: 2213 ARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGF 2272

Query: 324  CERRG-TGAFKSRV-GLPA---PAPVINSKYGLRETDKR--LNRLKKLGDSSKNSDSQSV 376
             + RG  G    RV GL +     P+   K   R  +KR   ++LKK         S+++
Sbjct: 2273 EKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENI 2332

Query: 377  SSNTDADTTQEKNNATSNRKSSVGVK 402
            ++ T   T Q +    SNR+ +  +K
Sbjct: 2333 NTPTRL-TPQLQMKPMSNRERNFVLK 2357


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 99/482 (20%), Positives = 163/482 (33%), Gaps = 77/482 (15%)

Query: 359 NRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRI 418
           +++KK       S S S SS++D+D++ +  +++ +  S    ++ SK R          
Sbjct: 181 SKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR---------- 230

Query: 419 PASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLK 478
                    K  H  NSR  KK KK  K         +  + LE +  S         + 
Sbjct: 231 ---------KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIP 281

Query: 479 EPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYIT 538
           E + ++ K+ P   +KE +             R   RE   NP         S P +Y  
Sbjct: 282 ENRFLMRKSPPKADEKERK------------NRERERERECNP-------PNSQPASY-Q 321

Query: 539 RRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEE--ELAHETAQ 596
           RR + TR      S  K++      Y++       D   + +  P  ++E          
Sbjct: 322 RRLLVTR------SGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVS 375

Query: 597 KGE--AKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGE 654
            GE   K  KS+    K+  R    VK+  KI +   V +SP + +     +  H    +
Sbjct: 376 SGERWIKGDKSELNEIKENQRSPVRVKE-RKITDHRNVSESPNRKNEKEKKVKDHKSNSK 434

Query: 655 HSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSG 714
               +       D   + V     +    K+K+     KSK K R ++++          
Sbjct: 435 ER-DIRRNSEKDDKYKNKVKKRAKSKSRSKSKE-----KSKSKERDSKHNR--------- 479

Query: 715 IPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSS 774
                  +R  S SK  D EN      K S    KD +   +   +K     ++    S 
Sbjct: 480 ----NEEKRMRSRSKGRDHEN-VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSK 534

Query: 775 TKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEG 834
           +K K +  +        T+G H          S    R    D S+     T D   S  
Sbjct: 535 SKEKDRRAQSRSRECDITKGKHSYN-------SRTRERSRSRDRSRRVRSRTHDRDRSRS 587

Query: 835 DE 836
            E
Sbjct: 588 KE 589



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 10/128 (7%)

Query: 345 INSKYGLRETDKRLN-RLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKK 403
           I     + E+  R N + KK+ D   NS  + +  N++ D  + KN      KS    K 
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDD-KYKNKVKKRAKSKSRSKS 464

Query: 404 NSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQ 463
             KS++  R S       + +   ++   +  R  + +K+  K   SK K +   +R   
Sbjct: 465 KEKSKSKERDS-----KHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ---ERSRS 516

Query: 464 KNASRKLE 471
           K  S++LE
Sbjct: 517 KEKSKQLE 524


>gi|148612801 KIAA1009 protein [Homo sapiens]
          Length = 1403

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 20/126 (15%)

Query: 738 MNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHE 797
           + SS  S+ LS D    N L V++LN+        SS  + +    ++E +  +   L E
Sbjct: 90  LKSSGTSL-LSTDSLETNELVVSELNH--------SSLGVGLDTLEEQEEKEQFFARL-E 139

Query: 798 NGVCCSDPLSLLESRMEVDDYSQYEE--------ESTDDSSSSEGDEEE--DDYDDDFED 847
            G+  S   S L   ++ +D + ++         E TDD   +E   EE  ++Y DDFED
Sbjct: 140 KGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDDFED 199

Query: 848 DFIPLP 853
           +++  P
Sbjct: 200 EYVGAP 205


>gi|12232401 SET and MYND domain containing 3 [Homo sapiens]
          Length = 369

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 11/73 (15%)

Query: 269 AFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNE----------F 318
           + +NH C PNC  V  G     ++A+RDIE GEE++  Y D                   
Sbjct: 143 SLLNHSCDPNCSIVFNG-PHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFE 201

Query: 319 CECYTCERRGTGA 331
           C+C+ C+ +   A
Sbjct: 202 CDCFRCQTQDKDA 214


>gi|68508961 centromere protein C 1 [Homo sapiens]
          Length = 943

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 65/274 (23%), Positives = 113/274 (41%), Gaps = 30/274 (10%)

Query: 366 DSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSR-IPASSNS 424
           +S +N +      N D  + ++     S + S+   K+ SK +  + +S ++ +P    S
Sbjct: 457 NSDRNMEEHEEMGN-DCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTS 515

Query: 425 TSSKLTHINNSRVPKK---LKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPK 481
           T +K   I  SR P     +K    P+ S   +RN        N+SRK        +  K
Sbjct: 516 TVTKSRRI--SRRPSDWWVVKSEESPVYSNSSVRNELPM--HHNSSRKST--KKTNQSSK 569

Query: 482 VVLYKNLPIKKDKEPEGPAQA------AVASGCLTRH--AAREHRQNPVRGAHS---QGE 530
            +  K +P+K+ K      Q       A  SG +  H   +R     P+    +   + +
Sbjct: 570 NIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKK 629

Query: 531 SSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSV-TEPCPDSGEQLQPAPVLQE-- 587
           +  C+  TR S +   N+  A ++ L+P T +GY  ++ TE   DSGE      VL+E  
Sbjct: 630 NLDCSRSTRSS-KNEDNIMTAQNVPLKPQT-SGYTCNIPTESNLDSGE--HKTSVLEESG 685

Query: 588 -EELAHETAQKGEAKCHKSDTGMSKKKSRQGKLV 620
              L +     G+      +   S   S+Q K++
Sbjct: 686 PSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVI 719


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 67/280 (23%), Positives = 113/280 (40%), Gaps = 36/280 (12%)

Query: 427 SKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYK 486
           +KL    +SR  + LK  AKPL SK        R E K  + ++   N V K PKV   +
Sbjct: 533 TKLKQRADSR--ESLKPAAKPLPSK------SVRKESKEETPEVTKVNHVEKPPKVESKE 584

Query: 487 NLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRT 546
            + +KKDK    P +         +    +   +PV+   ++ ++   T +  ++ + +T
Sbjct: 585 KVMVKKDK----PIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQA---TDVKPKAAKEKT 637

Query: 547 NLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEE----ELAHETAQKGEAKC 602
             KE    K++P      K    +P  +  ++    P+ +EE    E   +  +K   K 
Sbjct: 638 VKKET---KVKP---EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE 691

Query: 603 HKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVP--DLMGPHSDQGEHSGTVG 660
            K +     KK    K VK+  K EE   V     K++  P  ++     D  + S    
Sbjct: 692 EKKEPKKEVKKETPPKEVKKEVKKEEKKEVK----KEEKEPKKEIKKLPKDAKKSS---- 743

Query: 661 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRI 700
            P+S     P+ +   V   +    KDS    K K+K +I
Sbjct: 744 TPLSEAK-KPAALKPKVPKKEESVKKDSVAAGKPKEKGKI 782



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 5/87 (5%)

Query: 383  DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK 442
            + T+ K   T  + SS   K + KS+ L   + S  PA    +S K++ + + +  + ++
Sbjct: 2241 EKTKTKKPGTKTKSSSPVKKSDGKSKPL---AASPKPAGLKESSDKVSRVASPKKKESVE 2297

Query: 443  KPAKPLLS-KIK-LRNHCKRLEQKNAS 467
            K AKP  + ++K  R   K  E KNA+
Sbjct: 2298 KAAKPTTTPEVKAARGEEKDKETKNAA 2324


>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 359 NRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRI 418
           N ++KL     N     +   +   +     + +  R SS   +  S+SR+ +R+S SR 
Sbjct: 159 NAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSS---RSRSRSRSRSRKSYSRS 215

Query: 419 PASSNSTS-SKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGN 474
            + S S S SK   ++ S VP+K +K      SK       +R   ++ SR ++ GN
Sbjct: 216 RSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272


>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 359 NRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRI 418
           N ++KL     N     +   +   +     + +  R SS   +  S+SR+ +R+S SR 
Sbjct: 159 NAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSS---RSRSRSRSRSRKSYSRS 215

Query: 419 PASSNSTS-SKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGN 474
            + S S S SK   ++ S VP+K +K      SK       +R   ++ SR ++ GN
Sbjct: 216 RSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 55/283 (19%), Positives = 102/283 (36%), Gaps = 36/283 (12%)

Query: 586 QEEELAHETAQKGEAKCHKSDTGMSKKKSRQ--GKLVKQFAKIEESTPVHDSPGKDDAVP 643
           +E++      ++     HK    +S  ++R+  G +V +  +    T     P K+    
Sbjct: 443 EEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEK 502

Query: 644 DLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITR- 702
           +  G  S  G  S       S T    S V  S  +S S  ++ S R++  K+K+R +R 
Sbjct: 503 EKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561

Query: 703 --------------YDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLS 748
                         Y  ++ +E+N    K+  RRR + +S   ++  +   S +     S
Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRS 621

Query: 749 KDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSL 808
           +  D   N           +    S  + KI     ++ RG+ +   H++     +    
Sbjct: 622 RSRDRRTN----------RASRSRSRDRRKI-----DDQRGNLSGNSHKHKGEAKEQERK 666

Query: 809 LESRMEVD---DYSQYEEESTDDSSSSEGDEEEDDYDDDFEDD 848
            E    +D        E E   D    +   EE D+    +DD
Sbjct: 667 KERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 20/86 (23%), Positives = 37/86 (43%)

Query: 352 RETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLT 411
           ++T++    + +     +NS S   +   D D   EK    +   S +  KK  K +   
Sbjct: 446 QQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQ 505

Query: 412 RQSMSRIPASSNSTSSKLTHINNSRV 437
            +S S   +S +S+S+  T   +S V
Sbjct: 506 GRSRSGSSSSGSSSSNSRTSSTSSTV 531


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 55/283 (19%), Positives = 102/283 (36%), Gaps = 36/283 (12%)

Query: 586 QEEELAHETAQKGEAKCHKSDTGMSKKKSRQ--GKLVKQFAKIEESTPVHDSPGKDDAVP 643
           +E++      ++     HK    +S  ++R+  G +V +  +    T     P K+    
Sbjct: 443 EEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEK 502

Query: 644 DLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITR- 702
           +  G  S  G  S       S T    S V  S  +S S  ++ S R++  K+K+R +R 
Sbjct: 503 EKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561

Query: 703 --------------YDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLS 748
                         Y  ++ +E+N    K+  RRR + +S   ++  +   S +     S
Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRS 621

Query: 749 KDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSL 808
           +  D   N           +    S  + KI     ++ RG+ +   H++     +    
Sbjct: 622 RSRDRRTN----------RASRSRSRDRRKI-----DDQRGNLSGNSHKHKGEAKEQERK 666

Query: 809 LESRMEVD---DYSQYEEESTDDSSSSEGDEEEDDYDDDFEDD 848
            E    +D        E E   D    +   EE D+    +DD
Sbjct: 667 KERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 20/86 (23%), Positives = 37/86 (43%)

Query: 352 RETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLT 411
           ++T++    + +     +NS S   +   D D   EK    +   S +  KK  K +   
Sbjct: 446 QQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQ 505

Query: 412 RQSMSRIPASSNSTSSKLTHINNSRV 437
            +S S   +S +S+S+  T   +S V
Sbjct: 506 GRSRSGSSSSGSSSSNSRTSSTSSTV 531


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 5/122 (4%)

Query: 351 LRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTL 410
           +++T+K+LN++ K  + +K   +Q      D    ++  +ATS  K      +  K +  
Sbjct: 369 VKDTEKKLNKITKFIEENKEKFTQL--DLEDVQVREKLKHATSKAKKLEKQLQKDKEKV- 425

Query: 411 TRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKL 470
             +    IPA SN+  ++ T  NN+   +K K+  K       L+   + L+++  SR+ 
Sbjct: 426 --EEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483

Query: 471 EM 472
           E+
Sbjct: 484 EL 485


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 5/122 (4%)

Query: 351 LRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTL 410
           +++T+K+LN++ K  + +K   +Q      D    ++  +ATS  K      +  K +  
Sbjct: 369 VKDTEKKLNKITKFIEENKEKFTQL--DLEDVQVREKLKHATSKAKKLEKQLQKDKEKV- 425

Query: 411 TRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKL 470
             +    IPA SN+  ++ T  NN+   +K K+  K       L+   + L+++  SR+ 
Sbjct: 426 --EEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483

Query: 471 EM 472
           E+
Sbjct: 484 EL 485


>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
          Length = 714

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 19/123 (15%)

Query: 322 YTCE-RRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSK-------NSDS 373
           Y C+   G   F SRV L  P P  ++K   +  DK+L + +K  DSS        NS+ 
Sbjct: 241 YYCDVESGRYQFHSRVDLQ-PYPTSSTK---QSKDKKLKKKRKDPDSSATNEEKDLNSED 296

Query: 374 QSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKL-THI 432
           Q   S       +E+N A   +K+ +G+   +    +T      +P S N+  S L  +I
Sbjct: 297 QKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVT------VPTSGNTIESPLHENI 350

Query: 433 NNS 435
           +NS
Sbjct: 351 SNS 353



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 20/145 (13%)

Query: 717 KLTLRRRHDSSSKTNDQENDGMNSSK-ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSST 775
           KL  +R+   SS TN++++      K  S++ +  ++ +N    A +      G    ++
Sbjct: 273 KLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEEN---FANMKKKAKIGIHHKNS 329

Query: 776 KLKIQLKRDEENRGSYTEG-LHENGVCCSDPLSLLESRMEVDDYSQYE--------EEST 826
             K+ +       G+  E  LHEN    S+  S  + ++   D    E        E+S 
Sbjct: 330 PPKVTVPTS----GNTIESPLHEN---ISNSTSFKDEKIMETDSEPEEGEITDSQTEDSY 382

Query: 827 DDSSSSEGDEEEDDYDDDFEDDFIP 851
           D++ +SEG+   +D +D+ ED   P
Sbjct: 383 DEAITSEGNVTAEDSEDEDEDKIWP 407


>gi|54633315 deoxynucleotidyltransferase, terminal, interacting
           protein 2 [Homo sapiens]
          Length = 756

 Score = 38.5 bits (88), Expect = 0.028
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 4/75 (5%)

Query: 811 SRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDID 870
           S + +++  + EE+   +  SS+ DE ED++ D  E+DF+    AK L+L     SID  
Sbjct: 512 SEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSD--EEDFLNSTKAKLLKLT--SSSIDPG 567

Query: 871 ISSRRREDQSLRLNA 885
           +S ++     +  NA
Sbjct: 568 LSIKQLGGLYINFNA 582


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 38.5 bits (88), Expect = 0.028
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 10/114 (8%)

Query: 268  AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTC 324
            A F+NH C+PNC   K+   G     + AL DI+ G E++  Y     G     C+C   
Sbjct: 1747 ARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKC--- 1803

Query: 325  ERRGTGAFKSRVGL-PAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVS 377
               G       +G+ P   P+   +   +   K+  + +  G+ +K  + +  S
Sbjct: 1804 ---GAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFS 1854


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
            [Homo sapiens]
          Length = 2696

 Score = 38.5 bits (88), Expect = 0.028
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 10/114 (8%)

Query: 268  AAFINHDCRPNC---KFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTC 324
            A F+NH C+PNC   K+   G     + AL DI+ G E++  Y     G     C+C   
Sbjct: 2016 ARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKC--- 2072

Query: 325  ERRGTGAFKSRVGL-PAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVS 377
               G       +G+ P   P+   +   +   K+  + +  G+ +K  + +  S
Sbjct: 2073 ---GAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFS 2123


>gi|23957698 luman-recruiting factor [Homo sapiens]
          Length = 639

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 5/85 (5%)

Query: 768 SGSGSSSTKLKIQLKRDEENRGSY--TEGLHENGVCCSDPLSLLESRMEVDDYSQYEEES 825
           S S S+ST +    ++ EE+  S   ++ L E    CS P    E   +VDD    E   
Sbjct: 316 SSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCS-PEEDEEDEEDVDDEDHDEGFG 374

Query: 826 TDD--SSSSEGDEEEDDYDDDFEDD 848
           ++   S + E +EEE+DY+DD +DD
Sbjct: 375 SEHELSENEEEEEEEEDYEDDKDDD 399


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 40/183 (21%), Positives = 77/183 (42%), Gaps = 23/183 (12%)

Query: 678 VTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGI--------PKLTLRRRHDSSSK 729
           + S   K+   ++  + ++  R  R DA   +  +S          P+ T  R+ D   +
Sbjct: 84  IVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERR 143

Query: 730 TNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNN---GFNSGSGSSSTKLKIQLKRDEE 786
                 DG  S +I +++ +     +     ++N+   G +  +GSS +        DE+
Sbjct: 144 AKSPTPDG--SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSS-------DEQ 194

Query: 787 --NRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDD 844
             N  +  EG+ E+     +     E   EVD+  + EEE  ++    E +EEE++Y+ D
Sbjct: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE-EEEEEEYEQD 253

Query: 845 FED 847
             D
Sbjct: 254 ERD 256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,706,097
Number of Sequences: 37866
Number of extensions: 1682698
Number of successful extensions: 10046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 7938
Number of HSP's gapped (non-prelim): 1711
length of query: 885
length of database: 18,247,518
effective HSP length: 111
effective length of query: 774
effective length of database: 14,044,392
effective search space: 10870359408
effective search space used: 10870359408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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