Guide to the Human Genome
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Search of human proteins with 4885373

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885373 histone cluster 1, H1a [Homo sapiens]
         (215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885373 histone cluster 1, H1a [Homo sapiens]                      405   e-113
gi|4885379 histone cluster 1, H1e [Homo sapiens]                      271   4e-73
gi|4885377 histone cluster 1, H1d [Homo sapiens]                      255   2e-68
gi|4885381 histone cluster 1, H1b [Homo sapiens]                      253   1e-67
gi|4885375 histone cluster 1, H1c [Homo sapiens]                      245   2e-65
gi|20544168 histone cluster 1, H1t [Homo sapiens]                     173   1e-43
gi|4885371 H1 histone family, member 0 [Homo sapiens]                 112   2e-25
gi|5174449 H1 histone family, member X [Homo sapiens]                  94   1e-19
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     67   9e-12
gi|32401437 H1 histone family, member N, testis-specific [Homo s...    65   3e-11
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    56   2e-08
gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho...    55   4e-08
gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom...    55   4e-08
gi|153791662 coiled-coil domain containing 71 [Homo sapiens]           51   6e-07
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    47   1e-05
gi|104526627 triadin [Homo sapiens]                                    47   1e-05
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    46   3e-05
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s...    45   5e-05
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    45   5e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra...    45   6e-05
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    45   6e-05
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    45   6e-05
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    45   6e-05
gi|56676330 HP1-BP74 [Homo sapiens]                                    45   6e-05
gi|109637763 calpastatin isoform h [Homo sapiens]                      44   1e-04
gi|109637757 calpastatin isoform e [Homo sapiens]                      44   1e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         43   2e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   42   3e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   42   3e-04

>gi|4885373 histone cluster 1, H1a [Homo sapiens]
          Length = 215

 Score =  405 bits (1042), Expect = e-113
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
Sbjct: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
           SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
Sbjct: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120

Query: 121 PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV 180
           PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV
Sbjct: 121 PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV 180

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
Sbjct: 181 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score =  271 bits (692), Expect = 4e-73
 Identities = 155/222 (69%), Positives = 171/222 (77%), Gaps = 10/222 (4%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           MSET P APAA A  EK    KKA+K   +A A+K+K +GP VSELI +A ++SKER GV
Sbjct: 1   MSETAPAAPAAPAPAEKTPVKKKARK---SAGAAKRKASGPPVSELITKAVAASKERSGV 57

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
           SLAALKKALAAAGYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117

Query: 121 PGASK--VATKTKATGASKKLKKATGAS---KKSVKTPKKAKKPAAT--RKSSKNPKKPK 173
           P A K   A   K  GA+KK KKATGA+   K + KTPKKAKKPAA    K +K+PKK K
Sbjct: 118 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK 177

Query: 174 TVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
             KPKK  KSPAKAKAVKPKAAK +  KPK AKPKKAA KKK
Sbjct: 178 AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK 219


>gi|4885377 histone cluster 1, H1d [Homo sapiens]
          Length = 221

 Score =  255 bits (651), Expect = 2e-68
 Identities = 151/223 (67%), Positives = 166/223 (74%), Gaps = 10/223 (4%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           MSET P AP   A  EK    KKAKK    A A K+K +GP VSELI +A ++SKER GV
Sbjct: 1   MSETAPLAPTIPAPAEKTPVKKKAKKAG--ATAGKRKASGPPVSELITKAVAASKERSGV 58

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
           SLAALKKALAAAGYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 59  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK 118

Query: 121 PGASK--VATKTKATGASKKLKKATGAS--KKSV-KTPKKAKKP---AATRKSSKNPKKP 172
           P A K   A   K  GA+KK KK  GA+  KKS+ KTPKK KKP   A T+K +K+ KK 
Sbjct: 119 PKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKV 178

Query: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           KT +PKK AKSPAKAKA KPKAAK +  KPK  K KKAAPKKK
Sbjct: 179 KTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK 221


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score =  253 bits (645), Expect = 1e-67
 Identities = 147/220 (66%), Positives = 160/220 (72%), Gaps = 6/220 (2%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           MSET P   A  A  EK  A KKA K A  A A+K+K  GP VSELI +A ++SKER G+
Sbjct: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
           SLAALKKALAA GYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120

Query: 121 PGASK--VATKTKATGAS-KKLKKATGASKKSVKTPKKAKKPAA--TRKSSKNPKKPK-T 174
           P A K   A   K  GA+ KK KKA GA K   KTPKKAKKPAA   +K +K+PKK K  
Sbjct: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA 180

Query: 175 VKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
            KPKK  KSPAK KAVKPKAAK +  KPK AKPK A  KK
Sbjct: 181 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220


>gi|4885375 histone cluster 1, H1c [Homo sapiens]
          Length = 213

 Score =  245 bits (625), Expect = 2e-65
 Identities = 149/223 (66%), Positives = 164/223 (73%), Gaps = 18/223 (8%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           MSET P APAA+   EK    KKA   AK A  + +K +GP VSELI +A ++SKER GV
Sbjct: 1   MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV 57

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
           SLAALKKALAAAGYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117

Query: 121 PGASKV-ATK-TKATGASKKLKKATGAS---KKSVKTPKKAKKPAA---TRKSSKNPKKP 172
           P   K   TK  K  GA+KK KKA G +   K + KTPKKAKKPAA   T+K +K+PKK 
Sbjct: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177

Query: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           K  KPKK AKS   AKAVKPKAA     KPK  KPKKAAPKKK
Sbjct: 178 KVAKPKKAAKS--AAKAVKPKAA-----KPKVVKPKKAAPKKK 213


>gi|20544168 histone cluster 1, H1t [Homo sapiens]
          Length = 207

 Score =  173 bits (438), Expect = 1e-43
 Identities = 113/213 (53%), Positives = 140/213 (65%), Gaps = 10/213 (4%)

Query: 1   MSETVPPAPAAS--AAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERG 58
           MSETVP A A++  AA EK    K+ +KPA   +AS+K P   SVS+LI +A S S+ER 
Sbjct: 1   MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVP-NLSVSKLITEALSVSQERV 59

Query: 59  GVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVE 118
           G+SL ALKKALAAAGYDVEKNNSRIKL +KSLV+KG LVQT+GTGASGSFKL+KK     
Sbjct: 60  GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS 119

Query: 119 TKPGASK-VATKTKATGASKKLKKATGASKKSVKTPKKAKKP-AATRKSSKNPKKPKTVK 176
           T+  A K V+ KTK    S+  K     S K+ KT K+AKKP A T K+ ++ +K K  K
Sbjct: 120 TRSKAKKSVSAKTKKLVLSRDSK-----SPKTAKTNKRAKKPRATTPKTVRSGRKAKGAK 174

Query: 177 PKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKK 209
            K+  KSP KA+A K K  +      + A  KK
Sbjct: 175 GKQQQKSPVKARASKSKLTQHHEVNVRKATSKK 207


>gi|4885371 H1 histone family, member 0 [Homo sapiens]
          Length = 194

 Score =  112 bits (281), Expect = 2e-25
 Identities = 85/198 (42%), Positives = 103/198 (52%), Gaps = 19/198 (9%)

Query: 24  AKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDVEKNNSRI 83
           A KP K A ASKK    P  S++IV A  + K R G S  +++K + +     E  +S+I
Sbjct: 10  AAKP-KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQI 68

Query: 84  KLGIKSLVSKGTLVQTKGTGASGSFKL------NKKASSVETKPGASKVATKTKATGASK 137
           KL IK LV+ G L QTKG GASGSF+L       K  +  +TK    KVAT  KA+   K
Sbjct: 69  KLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKK 128

Query: 138 KLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKA 197
              KA     K+    K  KK AAT K +K   KPKTVK K V       KA KPK  KA
Sbjct: 129 AASKAPTKKPKATPVKKAKKKLAATPKKAK---KPKTVKAKPV-------KASKPK--KA 176

Query: 198 RVTKPKTAKPKKAAPKKK 215
           +  KPK     K A KKK
Sbjct: 177 KPVKPKAKSSAKRAGKKK 194



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 22/65 (33%), Positives = 25/65 (38%)

Query: 7   PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66
           P  AAS AP K       KK  K  AA+ KK   P   +     AS  K+   V   A  
Sbjct: 126 PKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKS 185

Query: 67  KALAA 71
            A  A
Sbjct: 186 SAKRA 190


>gi|5174449 H1 histone family, member X [Homo sapiens]
          Length = 213

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 78/214 (36%), Positives = 104/214 (48%), Gaps = 10/214 (4%)

Query: 1   MSETVPPAPAASAAPEKPLAGKKAK-KPAKAAAASKKKPAGPSVSELIVQAASSSKERGG 59
           + E +P   A   A +   AG  A   P+K    SKKK      S+L+V+      ER G
Sbjct: 5   LEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLGERNG 64

Query: 60  VSLAAL-KKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVE 118
            SLA +  +A     +D +   + +K  IK+LV   TL+Q KGTGA+GSFKLN+K     
Sbjct: 65  SSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNRKKLEGG 124

Query: 119 TKPGASKVATKTKATGASKKLKKATGA--SKKSVKTPKKAKKP-AATRKSSKNPKKPKTV 175
            +   +  A    A  A K  K A GA  S+++ K P + +KP   + K     KK K  
Sbjct: 125 GERRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSHKKGAGAKKDKGG 184

Query: 176 KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKK 209
           K KK A   A  K VK KAAK  V  PK  K +K
Sbjct: 185 KAKKTA--AAGGKKVK-KAAKPSV--PKVPKGRK 213


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 61/223 (27%), Positives = 100/223 (44%), Gaps = 18/223 (8%)

Query: 3   ETVPPAPAASAAPEKPLAG---KKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGG 59
           ET  P    +A+PEK       ++AK PA+A +  K++   P+  +   +A S +KE   
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA- 558

Query: 60  VSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVET 119
                 K    A   + E+  S  ++            + K    + S +  K     E 
Sbjct: 559 ------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612

Query: 120 KPGA---SKVATKTKATGASKKLKKATGASKKSVKTPKKAKKP----AATRKSSKNPKKP 172
           K  A   S V  + K+    K  +KA   +K+  K+P+KAK P    A + + +K+P K 
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672

Query: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           +   P+K AKSP KA+A  P+ AK+ V +   +  K  +P K+
Sbjct: 673 EAKSPEK-AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 61/218 (27%), Positives = 94/218 (43%), Gaps = 7/218 (3%)

Query: 2   SETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVS 61
           +E   P    + +P +  + +KAK PAK  A S  +   P   E    A   S E+    
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587

Query: 62  LAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKP 121
                K+ A A    EK  S +K   KS     + V+ +    +   K  +KA S   + 
Sbjct: 588 AKEEAKSPAEAK-SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA-EVKSPEKAKSPTKEE 645

Query: 122 GASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKP----AATRKSSKNPKKPKTVKP 177
             S    K+     +K  +KA    K   K+P+KAK P    A + + +K+P K +   P
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705

Query: 178 KKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           +K AKSP K +A  P+ AK+ V +      K  +P K+
Sbjct: 706 EK-AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742



 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 63/230 (27%), Positives = 93/230 (40%), Gaps = 18/230 (7%)

Query: 3   ETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSEL-IVQAASSSKERGGVS 61
           E   P  A S   E+  + +KAK P KA A S +K   P  +E    + A S  +    S
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704

Query: 62  LAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKP 121
               K  +       EK  S +K   K+     + V+ +      + K  +KA +++ K 
Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKA-KSPEKAKTLDVKS 763

Query: 122 GASKVATKTKATGASKKL-KKATGASKKSVKTPKKAKKPA---ATRKSSKNPKKPKTVKP 177
             +K   K +A   + K  +KA    K+ VK+P+KAK P    A     + PKK +   P
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 178 KKVAKSPAKAKAVKPKAAKARVTKPKTAK------------PKKAAPKKK 215
            K  + P + K  +P         P T K            PKK APK K
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 18/214 (8%)

Query: 7   PAPAASAAPEKPLAGKK--AKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAA 64
           P  A + +PEK  +  K  AK P KA +  K++   P  ++  V+  + + E+       
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA------ 736

Query: 65  LKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSV---ETK- 120
            K  +       EK  S  K     + S       K    S + K  +KA S    E K 
Sbjct: 737 -KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795

Query: 121 PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV 180
           P  +K   K  A    K++ K     K+ VK+P K ++     K  + PKK +  K    
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPK-----KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
            K+  K  + K +A K    KPK  + K+ A +K
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 57/200 (28%), Positives = 74/200 (37%), Gaps = 12/200 (6%)

Query: 16   EKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYD 75
            EKP   K  + P KA    +K PA P   E       S KE      A   K        
Sbjct: 828  EKPQEVKVKEPPKKAE--EEKAPATPKTEE----KKDSKKEEAPKKEAPKPKVEEKKEPA 881

Query: 76   VEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGA 135
            VEK         K        V T    A    ++ + A   E    A K     KA   
Sbjct: 882  VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941

Query: 136  SKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAA 195
            SK  +K   A +K     +KAKKP    K+    K+      K ++K P+K KA   KA 
Sbjct: 942  SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE----DDKTLSKEPSKPKA--EKAE 995

Query: 196  KARVTKPKTAKPKKAAPKKK 215
            K+  T  K +KP + A + K
Sbjct: 996  KSSSTDQKDSKPPEKATEDK 1015



 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 13/212 (6%)

Query: 3   ETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSL 62
           E   P  A S   E+    +KAK P K  A S +K   P  ++ +   +  +K       
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------ 768

Query: 63  AALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPG 122
            A ++A + A    EK  S +K  +KS     + ++     A    K   K   V++   
Sbjct: 769 PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED---AKAPEKEIPKKEEVKSPVK 825

Query: 123 ASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAK 182
             +   + K     KK ++    +    +  K +KK  A +K +  PK  +  +P     
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885

Query: 183 SPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
             +K +A K +A      K K   P+K AP K
Sbjct: 886 KESKVEAKKEEAE----DKKKVPTPEKEAPAK 913



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 24/129 (18%), Positives = 54/129 (41%), Gaps = 4/129 (3%)

Query: 86  GIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGA 145
           G+  + S  T ++ K        + ++K + +  +       T+       K+ K+  G 
Sbjct: 425 GLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK 484

Query: 146 SKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTA 205
            ++      + ++     + +K+P   +   P+K AKSP K +A  P  AK+   +   +
Sbjct: 485 EEEG----GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540

Query: 206 KPKKAAPKK 214
             +  +P+K
Sbjct: 541 PAEVKSPEK 549


>gi|32401437 H1 histone family, member N, testis-specific [Homo
           sapiens]
          Length = 255

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 29/233 (12%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPS---------VSELIVQAASSSKE 56
           P    + A  E P    +++  +     ++K   GPS         VS+L++QA S+ K 
Sbjct: 14  PRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK- 72

Query: 57  RGGVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASS 116
             G++LAALKK L  AGY+V + + R +       +K TL++  G+ A+G F++  K   
Sbjct: 73  --GLTLAALKKELRNAGYEVRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRV-WKVPK 127

Query: 117 VETKPGASKVATKTKA----TGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKP 172
              KPG ++    T+A      A +  ++     +K+ +  ++  +  A  K+  N +  
Sbjct: 128 PRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARAR 187

Query: 173 KTVKPKKVAKSPAKAKAVKPKAAKA----------RVTKPKTAKPKKAAPKKK 215
           +T + +  AK P  A+A +   A A            T P++ K K+ + K +
Sbjct: 188 RTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR 240


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 16/212 (7%)

Query: 11  ASAAPEKPLAGKKAKKPAKAAAASKKKPAG---PSVSELIVQAASSSKERGGVSLAALKK 67
           +S +PE    G           +    P G   P V  ++++A  + ++R G S+AA+K 
Sbjct: 20  SSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRGTSVAAIKL 79

Query: 68  ALAAA--GYDVEKNNSRIKLGIKSLVSKGTLVQ---TKGTGASGSFKL-NKKASSVETKP 121
            +       DV +    +K  + + + +G L +   +K  GA+GSFKL  K    ++ + 
Sbjct: 80  YILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRK 139

Query: 122 GASKVATKTKATGASKKLKKATGASKKSV---KTPKKAKKPAATRKSSKNPKKPKTVKPK 178
            A   A +       K  KK + A +      K  K AK+PA   K  K P KP     +
Sbjct: 140 MAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPA---KVQKPPPKPGAA-TE 195

Query: 179 KVAKSPAKAKAVKPKAAKARVTKPKTAKPKKA 210
           K  K    AK  + ++ +AR   PK  K  +A
Sbjct: 196 KARKQGGAAKDTRAQSGEARKVPPKPDKAMRA 227



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 54/203 (26%), Positives = 81/203 (39%), Gaps = 30/203 (14%)

Query: 7   PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66
           P+ A    P      K AK+PAK     +K P  P        A   ++++GG    A K
Sbjct: 160 PSEAKEDPPNVGKVKKAAKRPAKV----QKPPPKPGA------ATEKARKQGG----AAK 205

Query: 67  KALAAAGYDVEKNNSRIKLGIKSLVSKGTL---VQTKGTGAS---GSFKLNKKASSVETK 120
              A +G +  K   +    +++  S G L    + KG+ +S          KA S  +K
Sbjct: 206 DTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSK 264

Query: 121 PGASKV------ATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKT 174
           P ASKV       TK K    +K  K   G + K+    K +         S+  + PK 
Sbjct: 265 PTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPK- 323

Query: 175 VKPKKVAKSPAKAKAVKPKAAKA 197
             P+K A  P KA + K  + +A
Sbjct: 324 -GPRK-AGLPIKASSSKVSSQRA 344



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 57/209 (27%), Positives = 78/209 (37%), Gaps = 37/209 (17%)

Query: 12  SAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAA 71
           S A E P    K KK AK  A  +K P  P        A   ++++GG    A K   A 
Sbjct: 161 SEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGA------ATEKARKQGG----AAKDTRAQ 210

Query: 72  AGYDVEKNNSRIKLGIKSLVSKGTL---VQTKGTGAS---GSFKLNKKASSVETKPGASK 125
           +G +  K   +    +++  S G L    + KG+ +S          KA S  +KP ASK
Sbjct: 211 SG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASK 269

Query: 126 VATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPA 185
           V       GA+   KK         K   KAK P A +  +     P      KV  +  
Sbjct: 270 VKN-----GAASPTKK---------KVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHL 315

Query: 186 KAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
             K   PK  +      K   P KA+  K
Sbjct: 316 SRKTEAPKGPR------KAGLPIKASSSK 338



 Score = 35.4 bits (80), Expect = 0.037
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 6/78 (7%)

Query: 142 ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPA-----KAKAVKP-KAA 195
           ATG  +  +  P  +K   AT      PK  K ++P+K+A + A     +AK   P K +
Sbjct: 102 ATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPS 161

Query: 196 KARVTKPKTAKPKKAAPK 213
           +A+   P   K KKAA +
Sbjct: 162 EAKEDPPNVGKVKKAAKR 179


>gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo
           sapiens]
          Length = 1687

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 15/163 (9%)

Query: 35  KKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAA-GYDVEKNNSRIKLGIKSLVSK 93
           K+K   P    +I+ A      + GVS+ ++ K +++   YDV++N S +K  +K L+ +
Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493

Query: 94  GTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTP 153
           G + Q KG G SG+F L K     +         TK +A G+ +K++K T   K   K  
Sbjct: 494 GLVKQIKGHGFSGTFTLGKNYKEEDICD-----KTKKQAVGSPRKIQKET--RKSGNKDT 546

Query: 154 KKAKKPAATRKSSKNP-------KKPKTVKPKKVAKSPAKAKA 189
                P+ T     +P       ++ ++   KK+  S  K K+
Sbjct: 547 DSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKS 589


>gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo
           sapiens]
          Length = 1659

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 15/163 (9%)

Query: 35  KKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAA-GYDVEKNNSRIKLGIKSLVSK 93
           K+K   P    +I+ A      + GVS+ ++ K +++   YDV++N S +K  +K L+ +
Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493

Query: 94  GTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTP 153
           G + Q KG G SG+F L K     +         TK +A G+ +K++K T   K   K  
Sbjct: 494 GLVKQIKGHGFSGTFTLGKNYKEEDICD-----KTKKQAVGSPRKIQKET--RKSGNKDT 546

Query: 154 KKAKKPAATRKSSKNP-------KKPKTVKPKKVAKSPAKAKA 189
                P+ T     +P       ++ ++   KK+  S  K K+
Sbjct: 547 DSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKS 589


>gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
          Length = 467

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 47/136 (34%), Positives = 61/136 (44%), Gaps = 10/136 (7%)

Query: 86  GIKSLVSKGTLV-QTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATG 144
           G K L  KG      +G+G          + SV    G S + TKT     ++ L KA  
Sbjct: 235 GPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAAR 294

Query: 145 ASKKSVKTPKKAKKPAATRKSSKNPKKPKT----VKPK-KV----AKSPAKAKAVKPKAA 195
           A  K  +T  KA K  A  K+++   K K     VK K KV    AK+ AKAKAV+ KA 
Sbjct: 295 AQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAK 354

Query: 196 KARVTKPKTAKPKKAA 211
            AR       +PK +A
Sbjct: 355 VARTQPRGRGRPKGSA 370



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 23/204 (11%)

Query: 16  EKPLAGKKA--KKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAG 73
           + PL  +K+  K P      + +K        L  +   +   RG    +   +A  +  
Sbjct: 207 DSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPS 266

Query: 74  YDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKAT 133
               K  S   LG K+  +K      K   A        +A    T+  A+K   K KA 
Sbjct: 267 VRRMKGGSA--LGTKTAQAKVARTLAKAARA--------QAKVARTQAKAAKARAKAKAA 316

Query: 134 GASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPK-KVAKSPAKAKAVKP 192
               K      A  K+ +   KAK  AA  K+     K K V+ K KVA++  + +    
Sbjct: 317 QVKAK------AKAKAAQVKAKAKVMAAWAKAK---AKAKAVRAKAKVARTQPRGRGRPK 367

Query: 193 KAAKARVT-KPKTAKPKKAAPKKK 215
            +AKAR T K +  +P+    K+K
Sbjct: 368 GSAKARTTRKGQKNRPETVGQKRK 391


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 146 SKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVK----PKAAKARVTK 201
           ++ S+   ++ KK     K+ K+PK+PK  K KK  K P   KA K    PK  KA+   
Sbjct: 630 NRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTAT 689

Query: 202 PKTAKPKKAAPKK 214
           PK    KK++ KK
Sbjct: 690 PKPKSSKKSSNKK 702



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 10/81 (12%)

Query: 137 KKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSP--AKAKAVKPKA 194
           KK KK +    K+ K PK+ K+P    K  K PK+PKT K  K+ K P   KAK   PK 
Sbjct: 641 KKKKKRS----KAKKDPKEPKEP----KEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKP 692

Query: 195 AKARVTKPKTAKPKKAAPKKK 215
             ++ +  K    + +A KKK
Sbjct: 693 KSSKKSSNKKPDSEASALKKK 713



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 1/84 (1%)

Query: 122 GASKVATKTKATGASKKLKKATGAS-KKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV 180
           G+ +   K K + A K  K+      KK  K PK  K P   ++  +   K  T KPK  
Sbjct: 636 GSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSS 695

Query: 181 AKSPAKAKAVKPKAAKARVTKPKT 204
            KS  K    +  A K +V K KT
Sbjct: 696 KKSSNKKPDSEASALKKKVNKGKT 719



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 3/112 (2%)

Query: 103 GASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASK--KSVKTPKKAKKPA 160
           G   + +LN+ +     +    K  +K K      K  K     K  K+ K PK  K+P 
Sbjct: 622 GGVDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPK 681

Query: 161 ATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
             +  +  P KPK+ K     K  ++A A+K K  K +    + +   K  P
Sbjct: 682 EKKAKTATP-KPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPP 732


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 69/226 (30%), Positives = 90/226 (39%), Gaps = 29/226 (12%)

Query: 8   APAASAAPEKPLAGKKAKKPAKA-----------------AAASKKKPAGPSVSELIVQA 50
           A AA+   EK    KK KKPA+                  A + KK+ + PS  ++  + 
Sbjct: 367 AQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKT 426

Query: 51  ASSSKERGGVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKL 110
             + +E G VS+   KKA+   G   EK    ++  I+   S  T    K        + 
Sbjct: 427 ERAKEEIGAVSI---KKAVP--GKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEE 481

Query: 111 NKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSK-NP 169
              AS  E +P   K    +KA G   K K      KK  K   + KK A    S K   
Sbjct: 482 KVPASLKEKEPETKKDEKMSKA-GKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQI 540

Query: 170 KKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
            K   VKP+K   S  K +    K  KA VT  KTAKPK   P KK
Sbjct: 541 HKQDIVKPEKTV-SHGKPEEKVLKQVKA-VTIEKTAKPK---PTKK 581



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 59/233 (25%), Positives = 84/233 (36%), Gaps = 29/233 (12%)

Query: 7   PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVS---LA 63
           P PA+ A  EK    KKA+K   +    K+K      SE         KE G  S     
Sbjct: 302 PTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQG 361

Query: 64  ALKKALAAAGYDVEKNNSRIKLGIKSLVS--KGTLVQTKGTGASGSFKLNKKASSVETKP 121
            +K A  AA    EK     K    + V   KG   + K      + K  KK  SV +  
Sbjct: 362 TVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPA-KSPKKEHSVPSDK 420

Query: 122 GASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP------------ 169
                  + K    +  +KKA    KK  KT K  ++     KS K              
Sbjct: 421 QVKAKTERAKEEIGAVSIKKAV-PGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGK 479

Query: 170 ----------KKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
                     K+P+T K +K++K+  + K   P+    +  KP+    K+A P
Sbjct: 480 EEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKP 532



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 8/106 (7%)

Query: 109 KLNKKASSVETKPGASKVATKTK----ATGASKKLKKATGASKKSVKTPKKAKKPAATRK 164
           K+  K +  E + G  KV  K K    AT   K  KK    +K   K  KKAK   A + 
Sbjct: 157 KIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAK--TAEKS 214

Query: 165 SSKNPKKPKTVKPKKVAKSPAKAKAVK--PKAAKARVTKPKTAKPK 208
             K  K+ K  K +KV ++ AK K V+  P   K +  K K A  K
Sbjct: 215 EEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSK 260



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 57/224 (25%), Positives = 77/224 (34%), Gaps = 78/224 (34%)

Query: 9   PAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKA 68
           P  S A   PL  ++A +P  A+ A ++K      +E  V + +  KE+  +     KK+
Sbjct: 284 PGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK----KKS 339

Query: 69  LAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVAT 128
                 DVEK                              K   KAS  ETK G  K+A 
Sbjct: 340 EKETAIDVEK------------------------------KEPGKAS--ETKQGTVKIA- 366

Query: 129 KTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAK 188
                        A  A+KK  K           ++ SK  KKP  V+  K  K   K K
Sbjct: 367 -------------AQAAAKKDEK-----------KEDSKKTKKPAEVEQPKGKKQEKKEK 402

Query: 189 AVKP-------------KAAKARVTKPK----TAKPKKAAPKKK 215
            V+P             K  KA+  + K        KKA P KK
Sbjct: 403 HVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKK 446



 Score = 34.3 bits (77), Expect = 0.082
 Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 41/144 (28%)

Query: 109 KLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAK---------KP 159
           K  KKA+  E      K  TKT A    K+ KKA  A K   KT K+ K           
Sbjct: 179 KPEKKATHKEKIEKKEKPETKTLA----KEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTA 234

Query: 160 AATRKSSKNPKKPKTVKPKKVAK-------------------------SPAKAKAVKPKA 194
           A  ++  K P KPK  + K+ A                           P ++ A+ P  
Sbjct: 235 AKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPL 294

Query: 195 AKARVTKPKTAKP---KKAAPKKK 215
              + ++P  A P   +K   KKK
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKK 318


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 3/104 (2%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKK 171
           +K   +  K  A K   K K T   KK KK     KK  KT  K K    T+K +   KK
Sbjct: 11  EKVHVITEKESAWKRGRKKKTT---KKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKK 67

Query: 172 PKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
             T   K+  K   K K  + +  K +  + K  K KK   KKK
Sbjct: 68  TTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKK 111


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 52/207 (25%), Positives = 77/207 (37%), Gaps = 25/207 (12%)

Query: 8   APAASAAPEKPLAGKKA---KKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAA 64
           AP+  A   K  + K A   K PA   AA+ K+P G     L  +A SSS E        
Sbjct: 376 APSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE------- 428

Query: 65  LKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGAS 124
                 ++  + EK    +        +K  L         GS    + +SS      + 
Sbjct: 429 -----ESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS----RDSSSDSDSSSSE 479

Query: 125 KVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSP 184
           +   KT  +   KK +K  G +  S     K  K  ++  SS +    +  +  K   SP
Sbjct: 480 EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP 539

Query: 185 AKAKAVKPKAAKARVTKPKTAKPKKAA 211
                 +P+A KA  T   TA+  KAA
Sbjct: 540 ------RPQAPKANGTSALTAQNGKAA 560



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 51/226 (22%), Positives = 85/226 (37%), Gaps = 15/226 (6%)

Query: 4   TVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLA 63
           T  PA   +AAP++P+ G +     KA ++S ++ +  S  E   +  +++K +     A
Sbjct: 395 TKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAA 454

Query: 64  ALKKALAA--------AGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGAS--GSFKLNKK 113
               A  A        +  D   +    +   KS V K       G   S   S K  K 
Sbjct: 455 LSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKA 514

Query: 114 ASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPK 173
            SS  +    S    + K  G      +A  A+  S  T +  K    + +  +  KK  
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574

Query: 174 TVKPK-----KVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
            V  K     K  ++ A  +A  P+A K ++  P T   +K   K+
Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKR 620



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 45/219 (20%), Positives = 79/219 (36%), Gaps = 13/219 (5%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAAL 65
           P   +  ++ E   + ++ KKP   A  SK     P   +    AA SS +      +  
Sbjct: 318 PVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK----AAESSSDSSDSDSSED 373

Query: 66  KKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTG---------ASGSFKLNKKASS 116
            +A +      + ++++  +  KS   K      +  G         A  S    + +SS
Sbjct: 374 DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS 433

Query: 117 VETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
            E K       TK KAT  +     A  A + S  +   +   ++  +  K  K     K
Sbjct: 434 EEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKK 493

Query: 177 PKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           P+KVA   A +K    K  KA  +   ++       ++K
Sbjct: 494 PQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 24/196 (12%)

Query: 24  AKKPAKAAAASKKKPAGPSVSELI---VQAASSSKERGGVSLAALKKALAAAGYDVEKNN 80
           A K AKA  A+++     S+ ++    +++A   + +   +    KKA   A     +++
Sbjct: 31  ANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDS 90

Query: 81  SRIKLGIKSLVSKGTLVQTKGTG---ASGSFKLNKKASSVETKPGASKVATKTKATGASK 137
           S  +  ++   +K   V  K  G      + K ++ +SS E+     +   K +     K
Sbjct: 91  SEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPV--QK 148

Query: 138 KLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKA 197
            +K    A+K     PKKAK   +   SS   + PK  KPK           + P   KA
Sbjct: 149 GVKPQAKAAKAP---PKKAKSSDSDSDSSSEDEPPKNQKPK-----------ITPVTVKA 194

Query: 198 RVTKPKTAKPKKAAPK 213
           +   P   KP +AAPK
Sbjct: 195 QTKAP--PKPARAAPK 208



 Score = 35.0 bits (79), Expect = 0.048
 Identities = 51/209 (24%), Positives = 81/209 (38%), Gaps = 10/209 (4%)

Query: 11  ASAAPEKPLA--GKKAKKPAKAAAASKKKPAGPSVSEL----IVQAASSSKERGGVSLAA 64
           ++  PE+ L   G  AKK  K A++S  + +     E+      +AA  +K  G     A
Sbjct: 60  SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKA 119

Query: 65  LKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGAS 124
             KA  ++  +   ++   +   K  V KG   Q K   A      +  + S  +     
Sbjct: 120 AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP 179

Query: 125 KVATKTKATGASKKLKKATGASKKSVKT-PKKAK-KPAATRKSSKNPKKPKTVKPKKVAK 182
               K K T  +  +K  T A  K  +  PK A  K A++  SS +       + +K A 
Sbjct: 180 PKNQKPKITPVT--VKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237

Query: 183 SPAKAKAVKPKAAKARVTKPKTAKPKKAA 211
           +P K    K   AKA V    T   K ++
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSS 266



 Score = 30.8 bits (68), Expect = 0.91
 Identities = 45/219 (20%), Positives = 79/219 (36%), Gaps = 32/219 (14%)

Query: 23  KAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDVEKNNSR 82
           + K P K A A+ K   G + S     ++SSS +      +  +KA A     V K    
Sbjct: 195 QTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDD-----SEEEKAAATPKKTVPKKQVV 249

Query: 83  IKLGIKSLVSKGTLVQTKGTGASGSFKLNKKA--------------------SSVETKPG 122
            K  +K+  +      +    +S   +  KK                      S+ T+P 
Sbjct: 250 AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPP 309

Query: 123 ASKVATKTKATGASKKLKKATGASKKSVKTPKKA------KKPAATRKSSKNPKKPKTVK 176
              V  +     +     ++  +S++  K P KA       KP   +K++++        
Sbjct: 310 KKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSD 369

Query: 177 PKKVAKSPAK-AKAVKPKAAKARVTKPKTAKPKKAAPKK 214
             +  ++P+K A   K  + K  VT    A    AAPK+
Sbjct: 370 SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQ 408


>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
           sapiens]
          Length = 758

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 60/230 (26%), Positives = 91/230 (39%), Gaps = 36/230 (15%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPA----GPSVSELI-VQAASSSKERGGV 60
           P AP        P  G+  K+ A     S+K+PA    G  VS +  ++A   SK + G 
Sbjct: 328 PGAPGEGPEARGPSLGEDTKE-ADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT 386

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120
                       G D +K  +  +   K+L ++  L     T  S    +   + +V  +
Sbjct: 387 ------------GSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPE 434

Query: 121 PGAS-----KVATKTKATGASK-KLKKATGASKKSVKTPKKAKKPA------ATRKSSKN 168
           P +S      V ++T ++GA + KLK A G +K  + TP+ A  P       ATR  +K 
Sbjct: 435 PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTK--IATPRGAAPPGQKGQANATRIPAKT 492

Query: 169 PKKPKTV----KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           P  PKT     +P K       +    P    +R   P    P    PKK
Sbjct: 493 PPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKK 542


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 42/219 (19%)

Query: 4   TVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLA 63
           T PPAP + +AP  P+  K+ K+   AAA        P V E   Q   +++E       
Sbjct: 807 TPPPAPPSPSAPP-PVVPKEEKEEETAAA--------PPVEEGEEQKPPAAEE------- 850

Query: 64  ALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGA 123
                      D  K    +K        +G     KG  A  +    + A   E K G 
Sbjct: 851 --------LAVDTGKAEEPVKSECTEEAEEGP---AKGKDAEAAEATAEGALKAEKKEGG 899

Query: 124 SKVATKTKATGA-----------SKKLKKATGASKKSVKTPKKA-KKPAATRKSSKNPKK 171
           S  AT  K++GA           + ++ +A G  K  + +P+ +   P    +++ +P+K
Sbjct: 900 SGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQK 959

Query: 172 P---KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKP 207
           P   K +K +  A  P   K  +P    A  TKP    P
Sbjct: 960 PLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAP 998


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 51/226 (22%), Positives = 92/226 (40%), Gaps = 34/226 (15%)

Query: 9   PAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSS----KERGGVSLA- 63
           PAA+AAPE   +  + + PA+  AA   +P  P+ +E    +A+SS    K   G + + 
Sbjct: 90  PAAAAAPEAGASPVEKEAPAEGEAA---EPGSPTAAEGEAASAASSTSSPKAEDGATPSP 146

Query: 64  ------------ALKKALAAAGYDVEKNNSRIKLG--IKSLVSKGTLVQTKGTGASGSFK 109
                       + KK+   +G+  +KN      G   ++  ++G   +  G  A+ + +
Sbjct: 147 SNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAE 206

Query: 110 LNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP 169
               +      PG    A +  A G   +  K   A+    K P   +  AA        
Sbjct: 207 AGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAA-------- 258

Query: 170 KKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215
           ++P  V+ KK  ++ A A A +  +A      P     ++AAP ++
Sbjct: 259 EEPSKVEEKKAEEAGASAAACEAPSAAG----PGAPPEQEAAPAEE 300


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 54/235 (22%), Positives = 87/235 (37%), Gaps = 26/235 (11%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAAL 65
           P  PA ++A    L  K  K    A A + +K A PS       + S SK    V+    
Sbjct: 753 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTT 812

Query: 66  KKALAAAGYD-------VEKNNSRIK-----LGIKSLVSKGTLVQTKGTGASGSFKLNKK 113
             A+A+ G         + K  + IK       +K + +K          ++ +  + K 
Sbjct: 813 AAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 872

Query: 114 ASSVETKPGASKVATKTKATGASKK------LKKATGASKKSVKTPKKAKKPAATRKSSK 167
            +   T P A  V ++ KAT    +      + K   ++K S  TP+ ++    T     
Sbjct: 873 TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL 932

Query: 168 NPKKPKTVKPKKVAKSP--AKAKAVKPKAAKARVTKP------KTAKPKKAAPKK 214
              + K    + +   P   +AK  K   A A   KP      KTA P  +A K+
Sbjct: 933 KNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQ 987



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 14/117 (11%)

Query: 101 GTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPA 160
           GTG   +   NK     E  P   K   KTK    ++  K +T  SK   +     K+PA
Sbjct: 680 GTGNDITTPPNK-----ELPPSPEK---KTKPLATTQPAKTST--SKAKTQPTSLPKQPA 729

Query: 161 ATRKSSKNPKKPKTVKPKKVAKSPAKAKAV---KPKAAKARVTKPKTAKPKKAAPKK 214
            T     N KKP ++    V  +P K  AV   +P    ++  KPK     KA  K+
Sbjct: 730 PTTIGGLN-KKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKR 785



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%)

Query: 17   KPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDV 76
            +P  G+   +    AAA+ +KP   +V++     AS+ K+  G      KK      Y  
Sbjct: 948  QPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKK----VSYSH 1003

Query: 77   EKNNSRIKLGIKSLVSKGTL-VQTKGTGASG-SFKLNKKASSVETKPGASKVATKTKATG 134
             ++    K  IK +   G + +Q K    S  S K   KA +++ KPG   V  +++   
Sbjct: 1004 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA-NIKHKPGGGDVKIESQKLN 1062

Query: 135  ASKKLKKATGA 145
              +K +   G+
Sbjct: 1063 FKEKAQAKVGS 1073


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 54/235 (22%), Positives = 87/235 (37%), Gaps = 26/235 (11%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAAL 65
           P  PA ++A    L  K  K    A A + +K A PS       + S SK    V+    
Sbjct: 488 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTT 547

Query: 66  KKALAAAGYD-------VEKNNSRIK-----LGIKSLVSKGTLVQTKGTGASGSFKLNKK 113
             A+A+ G         + K  + IK       +K + +K          ++ +  + K 
Sbjct: 548 AAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 607

Query: 114 ASSVETKPGASKVATKTKATGASKK------LKKATGASKKSVKTPKKAKKPAATRKSSK 167
            +   T P A  V ++ KAT    +      + K   ++K S  TP+ ++    T     
Sbjct: 608 TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL 667

Query: 168 NPKKPKTVKPKKVAKSP--AKAKAVKPKAAKARVTKP------KTAKPKKAAPKK 214
              + K    + +   P   +AK  K   A A   KP      KTA P  +A K+
Sbjct: 668 KNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQ 722



 Score = 35.4 bits (80), Expect = 0.037
 Identities = 50/203 (24%), Positives = 78/203 (38%), Gaps = 26/203 (12%)

Query: 15  PEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGY 74
           P+K     ++K P +     K + A P    +       +K RG      L   L  +  
Sbjct: 341 PQKMTEKSESKTPGEGKKEDKSRMAEPMKGYM-----RPTKSRG------LTPLLPKSTI 389

Query: 75  DVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATG 134
             ++ + ++K    +   +G  V   GTG   +   NK     E  P   K   KTK   
Sbjct: 390 QEQERHKQLKSAGIARPEEGRPV-VSGTGNDITTPPNK-----ELPPSPEK---KTKPLA 440

Query: 135 ASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAV---K 191
            ++  K +T  SK   +     K+PA T     N KKP ++    V  +P K  AV   +
Sbjct: 441 TTQPAKTST--SKAKTQPTSLPKQPAPTTIGGLN-KKPMSLASGLVPAAPPKRPAVASAR 497

Query: 192 PKAAKARVTKPKTAKPKKAAPKK 214
           P    ++  KPK     KA  K+
Sbjct: 498 PSILPSKDVKPKPIADAKAPEKR 520



 Score = 30.8 bits (68), Expect = 0.91
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 115 SSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKA--KKPAATRKSSKNPKKP 172
           S VE  P  S+VA       ASK ++       K ++TP+K   K  + T    K   K 
Sbjct: 306 SKVEAPP--SEVADTLVIMTASKGVRLPE-PKDKILETPQKMTEKSESKTPGEGKKEDKS 362

Query: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAA 211
           +  +P K    P K++ + P   K+ + + +  K  K+A
Sbjct: 363 RMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSA 401



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%)

Query: 17  KPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDV 76
           +P  G+   +    AAA+ +KP   +V++     AS+ K+  G      KK      Y  
Sbjct: 683 QPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKK----VSYSH 738

Query: 77  EKNNSRIKLGIKSLVSKGTL-VQTKGTGASG-SFKLNKKASSVETKPGASKVATKTKATG 134
            ++    K  IK +   G + +Q K    S  S K   KA +++ KPG   V  +++   
Sbjct: 739 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA-NIKHKPGGGDVKIESQKLN 797

Query: 135 ASKKLKKATGA 145
             +K +   G+
Sbjct: 798 FKEKAQAKVGS 808


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 54/235 (22%), Positives = 87/235 (37%), Gaps = 26/235 (11%)

Query: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAAL 65
           P  PA ++A    L  K  K    A A + +K A PS       + S SK    V+    
Sbjct: 753 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTT 812

Query: 66  KKALAAAGYD-------VEKNNSRIK-----LGIKSLVSKGTLVQTKGTGASGSFKLNKK 113
             A+A+ G         + K  + IK       +K + +K          ++ +  + K 
Sbjct: 813 AAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 872

Query: 114 ASSVETKPGASKVATKTKATGASKK------LKKATGASKKSVKTPKKAKKPAATRKSSK 167
            +   T P A  V ++ KAT    +      + K   ++K S  TP+ ++    T     
Sbjct: 873 TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL 932

Query: 168 NPKKPKTVKPKKVAKSP--AKAKAVKPKAAKARVTKP------KTAKPKKAAPKK 214
              + K    + +   P   +AK  K   A A   KP      KTA P  +A K+
Sbjct: 933 KNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQ 987



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 14/117 (11%)

Query: 101 GTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPA 160
           GTG   +   NK     E  P   K   KTK    ++  K +T  SK   +     K+PA
Sbjct: 680 GTGNDITTPPNK-----ELPPSPEK---KTKPLATTQPAKTST--SKAKTQPTSLPKQPA 729

Query: 161 ATRKSSKNPKKPKTVKPKKVAKSPAKAKAV---KPKAAKARVTKPKTAKPKKAAPKK 214
            T     N KKP ++    V  +P K  AV   +P    ++  KPK     KA  K+
Sbjct: 730 PTTIGGLN-KKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKR 785



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%)

Query: 17   KPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDV 76
            +P  G+   +    AAA+ +KP   +V++     AS+ K+  G      KK      Y  
Sbjct: 948  QPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKK----VSYSH 1003

Query: 77   EKNNSRIKLGIKSLVSKGTL-VQTKGTGASG-SFKLNKKASSVETKPGASKVATKTKATG 134
             ++    K  IK +   G + +Q K    S  S K   KA +++ KPG   V  +++   
Sbjct: 1004 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA-NIKHKPGGGDVKIESQKLN 1062

Query: 135  ASKKLKKATGA 145
              +K +   G+
Sbjct: 1063 FKEKAQAKVGS 1073


>gi|56676330 HP1-BP74 [Homo sapiens]
          Length = 553

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 7/167 (4%)

Query: 28  AKAAAASKKKPAG----PSVSELIVQAASSSKERGGVSLAALKKALAAA--GYDVEKNNS 81
           ++ A A K+ P      P +  ++ +A  +  ++ G S+ A++K +       ++E+   
Sbjct: 142 SQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGY 201

Query: 82  RIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKK 141
            +K  +K  +++G + Q KG GASGSF + +K+     K    K  +         KL+ 
Sbjct: 202 LLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRNRKNRSSAVDPEPQVKLED 261

Query: 142 ATGASKKSVKTPKKAKKPAATRKSSK-NPKKPKTVKPKKVAKSPAKA 187
               +   +  PK+A      +  S+  PK    ++P+ +  +  +A
Sbjct: 262 VLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQLLKNALQRA 308



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 47/210 (22%), Positives = 82/210 (39%), Gaps = 14/210 (6%)

Query: 19  LAGKKAKKPAKAAAASKKKPAGPSVSEL-IVQAASSSKERGGVSLAALKKALAAAGYDVE 77
           + GK A    +   + +K   G S+ E  I+ A ++  E    S  ALKK +        
Sbjct: 317 ITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTN 376

Query: 78  KNNSR--IKLGIKSLVSKGTLVQTKGTGASGSFKL------NKKASSVETKPGASKVATK 129
            N     +K  ++     G + Q  G G SG+F+L      +      + +P  S+   +
Sbjct: 377 SNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDEDE 436

Query: 130 TKATGASKKLKKATGASKKSV--KTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKA 187
            +   + +  +      K+ +  KTP K+   AA+ K   +   PK    ++    P   
Sbjct: 437 DEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPK 496

Query: 188 KAVKPKAAKARVTKPKTA---KPKKAAPKK 214
           KA       A+ T+P +    KP   + KK
Sbjct: 497 KAPPKAKTPAKKTRPSSTVIKKPSGGSSKK 526



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 51/203 (25%), Positives = 78/203 (38%), Gaps = 70/203 (34%)

Query: 83  IKLGIKSLVSKGTLVQTKGTGASGSFKLNKK------ASSVETKPGASKVAT----KTKA 132
           +K  ++  V +G L Q  G GASG+F+L K         S+      S +A     KT +
Sbjct: 301 LKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCS 360

Query: 133 TGASKK-----------------LKKATGASKKS-------------------------- 149
           T A KK                 LKK     +K+                          
Sbjct: 361 TTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPG 420

Query: 150 VKTPKK---------AKKPAATRKSSKNPKKP--KTVKPKKVAKSPAKAKAVKPKAAK-- 196
           V  PKK           +  ++ + S++ + P  + ++ K  AKSP KA +VK + +K  
Sbjct: 421 VLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPA 480

Query: 197 ARVTKPKTAK----PKKAAPKKK 215
            +V+  +  K    PKKA PK K
Sbjct: 481 PKVSAAQRGKARPLPKKAPPKAK 503



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 15/81 (18%)

Query: 7   PAPAASAAPE---KPLAGK---KAKKPAKAAAASK---KKPAGPSVSELIVQAASSSKER 57
           PAP  SAA     +PL  K   KAK PAK    S    KKP+G S  +    A S+ KE 
Sbjct: 479 PAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKK---PATSARKE- 534

Query: 58  GGVSLAALKKALAAAGYDVEK 78
             V L    K+     + V+K
Sbjct: 535 --VKLPGKGKSTMKKSFRVKK 553


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 110 LNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP 169
           +++K S   +KPG  K + + KA          T A   +  T   A   A ++ SS NP
Sbjct: 27  VSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP 86

Query: 170 KKPKTVKPKKVAKSPA-KAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
            + K VK +   KS + K   V  K  K++  KPK     K+ PK+
Sbjct: 87  TETKAVKTEPEKKSQSTKLSVVHEK--KSQEGKPKEHTEPKSLPKQ 130



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 28/188 (14%)

Query: 16  EKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYD 75
           +KP A   + +P +AAAA +         E + +  S S  + G    + +K  A+ G  
Sbjct: 6   QKPAA---SPRPRRAAAARR-------THEHVSEKTSESPSKPGEKKGSDEKKAASLG-- 53

Query: 76  VEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGA 135
               +SR   G       GT   TK + +SG+   +   +  ETK   ++   K+++T  
Sbjct: 54  -SSQSSRTYAG-------GTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKL 105

Query: 136 SKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAA 195
           S   +K +   K    T  K+    A+   S +    K V   + A+     K+ +PK  
Sbjct: 106 SVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAV--SRSAEQQPSEKSTEPK-- 161

Query: 196 KARVTKPK 203
               TKP+
Sbjct: 162 ----TKPQ 165



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 128 TKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPK 170
           T+T    A  K KKA  +SK + K   KAK  A T + +  PK
Sbjct: 726 TETSQNTAKDKCKKAASSSK-APKNGGKAKDSAKTTEETSKPK 767


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 110 LNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP 169
           +++K S   +KPG  K + + KA          T A   +  T   A   A ++ SS NP
Sbjct: 27  VSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP 86

Query: 170 KKPKTVKPKKVAKSPA-KAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
            + K VK +   KS + K   V  K  K++  KPK     K+ PK+
Sbjct: 87  TETKAVKTEPEKKSQSTKLSVVHEK--KSQEGKPKEHTEPKSLPKQ 130



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 28/188 (14%)

Query: 16  EKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYD 75
           +KP A   + +P +AAAA +         E + +  S S  + G    + +K  A+ G  
Sbjct: 6   QKPAA---SPRPRRAAAARR-------THEHVSEKTSESPSKPGEKKGSDEKKAASLG-- 53

Query: 76  VEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGA 135
               +SR   G       GT   TK + +SG+   +   +  ETK   ++   K+++T  
Sbjct: 54  -SSQSSRTYAG-------GTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKL 105

Query: 136 SKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAA 195
           S   +K +   K    T  K+    A+   S +    K V   + A+     K+ +PK  
Sbjct: 106 SVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAV--SRSAEQQPSEKSTEPK-- 161

Query: 196 KARVTKPK 203
               TKP+
Sbjct: 162 ----TKPQ 165



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 128 TKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPK 170
           T+T    A  K KKA  +SK + K   KAK  A T + +  PK
Sbjct: 713 TETSQNTAKDKCKKAASSSK-APKNGGKAKDSAKTTEETSKPK 754


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 53/213 (24%), Positives = 84/213 (39%), Gaps = 23/213 (10%)

Query: 7   PAPAASAAPEKP---LAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKE--RGGVS 61
           P+P+ + +P +P     G+ A  P KA   S KKPA P       +  +   E  + G  
Sbjct: 606 PSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDP 665

Query: 62  LAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKP 121
             A +K          +  +R     ++L   G+     G+  SGS   ++  S      
Sbjct: 666 REARRK----------ERPARTPPRRRTLSGSGS---GSGSSYSGSSSRSRSLSVSSVSS 712

Query: 122 GASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVA 181
            +S  ++ + A     +   A  AS  S     ++  PA TRK     KK   VK +K  
Sbjct: 713 VSSATSSSSSAHSVDSEDMYADLASPVS-SASSRSPAPAQTRKEKGKSKKEDGVKEEKRK 771

Query: 182 K--SPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
           +  S    K+ KP A      +P T  P++A P
Sbjct: 772 RDSSTQPPKSAKPPAGGKSSQQPST--PQQAPP 802


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 109 KLNKKASSVETKPGASKV-ATKTKATGASKK---------LKKATGA-----SKKSVKTP 153
           K+ K+ ++   K   SK+ AT T+ T  + +         LK  T A     +KK++ T 
Sbjct: 802 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 861

Query: 154 KKAKKPAATRKSSKNPKKPK--TVKPKKVAKSPAKAKAVKPKAAKARVTKPKTA-KPKK 209
           +   KP  T K        K  T KP+K  K+P K  + K      RV KPKT   P+K
Sbjct: 862 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 17/138 (12%)

Query: 91  VSKGTLVQTKGTGASG---SFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASK 147
           V+K T V+TK T  +    S    +K +S +      K + K  A   SK L K T  ++
Sbjct: 144 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLAKPTPKAE 202

Query: 148 KSVK----------TPKKAKKPAATRKSSKNPK--KPKTVKPKKVAKSPAKAKAVKPKAA 195
            + K          TP   K+PA+T      P   K     PK+ A +  K+    PK  
Sbjct: 203 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 262

Query: 196 KARVTK-PKTAKPKKAAP 212
               TK P    PK+ AP
Sbjct: 263 APTTTKEPAPTTPKEPAP 280



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 5/102 (4%)

Query: 118 ETKPGASKVATKTKATGASKKLKK-ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
           E  P  +K A  T    A    K+ A    K+   T  K   P  T+ +   PK+P    
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305

Query: 177 PKKVA----KSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           PKK A    K PA     +P     +   P T +P    PK+
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 18/119 (15%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP-- 169
           KK +  E  P  +K  T T     +    K T  +      P   K+PA T      P  
Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651

Query: 170 -KKPKTVKPKKVA---------KSPAKAKAVKPKAAKARVTKPKTAK------PKKAAP 212
            K+P    PKK A         K P    + KP     + T P T K      PKK AP
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/214 (23%), Positives = 77/214 (35%), Gaps = 12/214 (5%)

Query: 7   PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66
           P   A   P++P A    KKPA     +      P+ SE+     +        S     
Sbjct: 689 PKETAPTTPKEP-APTTPKKPAPTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST 743

Query: 67  KALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKV 126
             L+A        NS  + G+ +  +         T A          ++ ET   A K+
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803

Query: 127 ----ATKTKATGASKKLKKATGASKKSVK--TPKKAKKPAATRKSSKNPKKPKTVKPKKV 180
               AT T+ T  SK     T  +  + +  TP K      T  + K     KT+   ++
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
              P +    K +A  ++ T PK  KP K APKK
Sbjct: 864 MNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 896



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 3/98 (3%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKN-PKKPKTVK 176
           E  P   K    T    A    K+    + KS  T  K   P  T++ +   PK+P    
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 438

Query: 177 PKKVAKSPAK--AKAVKPKAAKARVTKPKTAKPKKAAP 212
           PKK A +  K  A     + A     KP    PK+ AP
Sbjct: 439 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 9/95 (9%)

Query: 127 ATKTKATGASKKLKKATGASKKSVKT------PKKAKKPAATRKSSKNPKKPKTVKPKKV 180
           A  TK    +   + A  A KK   T      P   K+PA T     +P  PK   P   
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 393

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKP---KKAAP 212
             +P   K   P   K+  T PK   P   K+ AP
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 128 TKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKA 187
           T TK+   + K    T   K +  TPK+   PA T      P  PK   P     +P   
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345

Query: 188 KAVKPKAAKARVTKPKTAKPKKAAP 212
           K   P A K    KP    PK+ AP
Sbjct: 346 KEPAPTAPK----KPAPTTPKEPAP 366



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 9/104 (8%)

Query: 113 KASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKP 172
           K++   TK  A    T TK+   + K    T   + +  TPK+       + +   PK+P
Sbjct: 394 KSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450

Query: 173 KTVKPKKVA----KSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
               PK+ A    K PA     +P     + T P T  PKK  P
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTP 492



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 45/196 (22%), Positives = 75/196 (38%), Gaps = 22/196 (11%)

Query: 14  APEKPLAGKKAKKPAKAAAASKKKPAGPSVS-------ELIVQAASSSKERGGVSLAALK 66
           +P++      A+   KA   S K+P  P+         E+   A   + ER    L    
Sbjct: 738 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER---DLRTTP 794

Query: 67  KALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKV 126
           +   AA    ++  +  +   K+  SK T   T+ T  +       K ++++T   A KV
Sbjct: 795 ETTTAAPKMTKETATTTE---KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV 851

Query: 127 ATKTKATGASKKLKKATGASK-------KSVKTPKKAKKPAATRK--SSKNPKKPKTVKP 177
            T  K    ++ + K    +K           TPK  K   A +K  S+K PK    V+ 
Sbjct: 852 TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 911

Query: 178 KKVAKSPAKAKAVKPK 193
            K   +P K  +  P+
Sbjct: 912 PKTTPTPRKMTSTMPE 927



 Score = 35.8 bits (81), Expect = 0.028
 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 11/97 (11%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKP 177
           E  P   +  T T     +    KA   +      P   K+PA T      PK+P    P
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-----TPKEPAPTTP 567

Query: 178 KKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           K+ A  P   K   P   K    +P    PKK APK+
Sbjct: 568 KETA--PTTPKGTAPTTLK----EPAPTTPKKPAPKE 598



 Score = 35.0 bits (79), Expect = 0.048
 Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 16/118 (13%)

Query: 109 KLNKKASSVETKPGASKVATKTKATG---ASKKLKKATGASKKSVKTPKKAKKPAATRKS 165
           K   KA +    P  +     T  T    AS   K+ T  + KS  T  K   P  T+ +
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255

Query: 166 SKNPKKPKT--------VKPKKVAKSPAKAKAVKPKAAKARVTKPK---TAKPKKAAP 212
              PK+P            PK+ A  P   K   P   K+  T PK      PKK AP
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 311



 Score = 34.3 bits (77), Expect = 0.082
 Identities = 52/217 (23%), Positives = 69/217 (31%), Gaps = 23/217 (10%)

Query: 4   TVPPAPAASAAPEK-PLAGKKAKK--PAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           T P  PA +   E  P   KK     P K A  + +KPA  +  EL              
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTG-----ASGSFKLNKKAS 115
             A      AA     E   +  K    +   +      K T       +    L + A 
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588

Query: 116 SVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTV 175
           +   KP   ++A  T     S    K    + K    P   K+PA T      PK+P   
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-APTTPKEPAPT-----TPKEPAPT 642

Query: 176 KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
            PK  A +  K  A          T PK   PK+ AP
Sbjct: 643 TPKGTAPTTLKEPA---------PTTPKKPAPKELAP 670



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 30/106 (28%), Positives = 38/106 (35%), Gaps = 10/106 (9%)

Query: 113 KASSVETKPGASKVATKTKATGASKK-LKKATGASKKSVKTPKKAKKPAATRKSSK---N 168
           K ++  T  G +    K  A    KK   K    +     T     KPA T         
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627

Query: 169 PKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           PK+P    PK+ A  P   K   P   K    +P    PKK APK+
Sbjct: 628 PKEPAPTTPKEPA--PTTPKGTAPTTLK----EPAPTTPKKPAPKE 667



 Score = 32.3 bits (72), Expect = 0.31
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 6/103 (5%)

Query: 118 ETKPGASKVATKTKATGASKKLKK-ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
           E  P  +K A  T    A    KK A    K+   T  K   P   ++ +   K+P    
Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 344

Query: 177 PKKVA----KSPAKAKAVKPKAAKARVTKPKTAK-PKKAAPKK 214
           PK+ A    K PA     +P     +   P T K P    PK+
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 27/114 (23%), Positives = 39/114 (34%), Gaps = 11/114 (9%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP-- 169
           KK +  E  P  +K  T T +   +    K T  +      P   KKPA T   +  P  
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 720

Query: 170 ---------KKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
                    K+P T+       +P  +    PKA +    +P     K  A  K
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 774



 Score = 30.8 bits (68), Expect = 0.91
 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 4/103 (3%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKK 171
           KK +    K  A     +T  T   KKL   T   K +  TP+K         +   P++
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPT-TPKKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEE 521

Query: 172 PKTVKPKKVAKSPAKAKAVKPKAAKARVT--KPKTAKPKKAAP 212
           P    P++ A +  KA A       A  T  +P    PK+ AP
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 26/107 (24%), Positives = 36/107 (33%), Gaps = 10/107 (9%)

Query: 116 SVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTV 175
           S  T P      T  +    + K    T   K +  TPK+         +    KKP   
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469

Query: 176 KPKKVA------KSPAKAKAVKP----KAAKARVTKPKTAKPKKAAP 212
            PK+ A       +P   K + P    K A     KP    P++ AP
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 47/210 (22%), Positives = 67/210 (31%), Gaps = 14/210 (6%)

Query: 3   ETVPPAPAASA--APEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           E  P  P A+A   P++P        P + A  + K+PA  +  E    A ++ K     
Sbjct: 529 EPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPT 581

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFK---LNKKASSV 117
           +L              E   +  K    +   K      KGT  +   +      K  + 
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641

Query: 118 ETKPGASKVATKTKATGASKK-LKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
            T  G +    K  A    KK   K    +     T   + KPA T      P  PK   
Sbjct: 642 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701

Query: 177 PKKVAKSPAKAKAVKPKAAKARVTKPKTAK 206
           P    K PA      P    + V+ P T K
Sbjct: 702 P-TTPKKPAPTTPETPPPTTSEVSTPTTTK 730



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 15/115 (13%)

Query: 100 KGTGASGSFKLNKKASSVETKPGASKVA-TKTKATGASKKLKKATGASKKSVKTPKKAKK 158
           KGT  +    L + A +   KP   ++A T TK   ++   K A    K++   P   K+
Sbjct: 645 KGTAPT---TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKE 699

Query: 159 PAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPK 213
           PA T      PKKP    P+     P  ++   P   K   T  K+  P ++ P+
Sbjct: 700 PAPT-----TPKKPAPTTPE--TPPPTTSEVSTPTTTKEPTTIHKS--PDESTPE 745



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 8/100 (8%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAAT---RKSSKNPKKPKT 174
           E  P   K  T T     +   K+    + K    P   KKPA T     +   PK+P  
Sbjct: 316 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAP 374

Query: 175 VKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKP--KKAAP 212
              K+   SP   K   P   K+  T  K   P   K+AP
Sbjct: 375 TTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 109 KLNKKASSVETKPGASKV-ATKTKATGASKK---------LKKATGA-----SKKSVKTP 153
           K+ K+ ++   K   SK+ AT T+ T  + +         LK  T A     +KK++ T 
Sbjct: 843 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 902

Query: 154 KKAKKPAATRKSSKNPKKPK--TVKPKKVAKSPAKAKAVKPKAAKARVTKPKTA-KPKK 209
           +   KP  T K        K  T KP+K  K+P K  + K      RV KPKT   P+K
Sbjct: 903 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 17/138 (12%)

Query: 91  VSKGTLVQTKGTGASG---SFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASK 147
           V+K T V+TK T  +    S    +K +S +      K + K  A   SK L K T  ++
Sbjct: 185 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLAKPTPKAE 243

Query: 148 KSVK----------TPKKAKKPAATRKSSKNPK--KPKTVKPKKVAKSPAKAKAVKPKAA 195
            + K          TP   K+PA+T      P   K     PK+ A +  K+    PK  
Sbjct: 244 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 303

Query: 196 KARVTK-PKTAKPKKAAP 212
               TK P    PK+ AP
Sbjct: 304 APTTTKEPAPTTPKEPAP 321



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 5/102 (4%)

Query: 118 ETKPGASKVATKTKATGASKKLKK-ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
           E  P  +K A  T    A    K+ A    K+   T  K   P  T+ +   PK+P    
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346

Query: 177 PKKVA----KSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           PKK A    K PA     +P     +   P T +P    PK+
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 18/119 (15%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP-- 169
           KK +  E  P  +K  T T     +    K T  +      P   K+PA T      P  
Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692

Query: 170 -KKPKTVKPKKVA---------KSPAKAKAVKPKAAKARVTKPKTAK------PKKAAP 212
            K+P    PKK A         K P    + KP     + T P T K      PKK AP
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/214 (23%), Positives = 77/214 (35%), Gaps = 12/214 (5%)

Query: 7   PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66
           P   A   P++P A    KKPA     +      P+ SE+     +        S     
Sbjct: 730 PKETAPTTPKEP-APTTPKKPAPTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST 784

Query: 67  KALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKV 126
             L+A        NS  + G+ +  +         T A          ++ ET   A K+
Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844

Query: 127 ----ATKTKATGASKKLKKATGASKKSVK--TPKKAKKPAATRKSSKNPKKPKTVKPKKV 180
               AT T+ T  SK     T  +  + +  TP K      T  + K     KT+   ++
Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
              P +    K +A  ++ T PK  KP K APKK
Sbjct: 905 MNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 937



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 3/98 (3%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKN-PKKPKTVK 176
           E  P   K    T    A    K+    + KS  T  K   P  T++ +   PK+P    
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 479

Query: 177 PKKVAKSPAK--AKAVKPKAAKARVTKPKTAKPKKAAP 212
           PKK A +  K  A     + A     KP    PK+ AP
Sbjct: 480 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 9/95 (9%)

Query: 127 ATKTKATGASKKLKKATGASKKSVKT------PKKAKKPAATRKSSKNPKKPKTVKPKKV 180
           A  TK    +   + A  A KK   T      P   K+PA T     +P  PK   P   
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 434

Query: 181 AKSPAKAKAVKPKAAKARVTKPKTAKP---KKAAP 212
             +P   K   P   K+  T PK   P   K+ AP
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 128 TKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKA 187
           T TK+   + K    T   K +  TPK+   PA T      P  PK   P     +P   
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386

Query: 188 KAVKPKAAKARVTKPKTAKPKKAAP 212
           K   P A K    KP    PK+ AP
Sbjct: 387 KEPAPTAPK----KPAPTTPKEPAP 407



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 9/104 (8%)

Query: 113 KASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKP 172
           K++   TK  A    T TK+   + K    T   + +  TPK+       + +   PK+P
Sbjct: 435 KSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491

Query: 173 KTVKPKKVA----KSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
               PK+ A    K PA     +P     + T P T  PKK  P
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTP 533



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 45/196 (22%), Positives = 75/196 (38%), Gaps = 22/196 (11%)

Query: 14  APEKPLAGKKAKKPAKAAAASKKKPAGPSVS-------ELIVQAASSSKERGGVSLAALK 66
           +P++      A+   KA   S K+P  P+         E+   A   + ER    L    
Sbjct: 779 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER---DLRTTP 835

Query: 67  KALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKV 126
           +   AA    ++  +  +   K+  SK T   T+ T  +       K ++++T   A KV
Sbjct: 836 ETTTAAPKMTKETATTTE---KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV 892

Query: 127 ATKTKATGASKKLKKATGASK-------KSVKTPKKAKKPAATRK--SSKNPKKPKTVKP 177
            T  K    ++ + K    +K           TPK  K   A +K  S+K PK    V+ 
Sbjct: 893 TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 952

Query: 178 KKVAKSPAKAKAVKPK 193
            K   +P K  +  P+
Sbjct: 953 PKTTPTPRKMTSTMPE 968



 Score = 35.8 bits (81), Expect = 0.028
 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 11/97 (11%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKP 177
           E  P   +  T T     +    KA   +      P   K+PA T      PK+P    P
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-----TPKEPAPTTP 608

Query: 178 KKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           K+ A  P   K   P   K    +P    PKK APK+
Sbjct: 609 KETA--PTTPKGTAPTTLK----EPAPTTPKKPAPKE 639



 Score = 35.0 bits (79), Expect = 0.048
 Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 16/118 (13%)

Query: 109 KLNKKASSVETKPGASKVATKTKATG---ASKKLKKATGASKKSVKTPKKAKKPAATRKS 165
           K   KA +    P  +     T  T    AS   K+ T  + KS  T  K   P  T+ +
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296

Query: 166 SKNPKKPKT--------VKPKKVAKSPAKAKAVKPKAAKARVTKPK---TAKPKKAAP 212
              PK+P            PK+ A  P   K   P   K+  T PK      PKK AP
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 352



 Score = 34.3 bits (77), Expect = 0.082
 Identities = 52/217 (23%), Positives = 69/217 (31%), Gaps = 23/217 (10%)

Query: 4   TVPPAPAASAAPEK-PLAGKKAKK--PAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           T P  PA +   E  P   KK     P K A  + +KPA  +  EL              
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTG-----ASGSFKLNKKAS 115
             A      AA     E   +  K    +   +      K T       +    L + A 
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629

Query: 116 SVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTV 175
           +   KP   ++A  T     S    K    + K    P   K+PA T      PK+P   
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-APTTPKEPAPT-----TPKEPAPT 683

Query: 176 KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAP 212
            PK  A +  K  A          T PK   PK+ AP
Sbjct: 684 TPKGTAPTTLKEPA---------PTTPKKPAPKELAP 711



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 30/106 (28%), Positives = 38/106 (35%), Gaps = 10/106 (9%)

Query: 113 KASSVETKPGASKVATKTKATGASKK-LKKATGASKKSVKTPKKAKKPAATRKSSK---N 168
           K ++  T  G +    K  A    KK   K    +     T     KPA T         
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668

Query: 169 PKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
           PK+P    PK+ A  P   K   P   K    +P    PKK APK+
Sbjct: 669 PKEPAPTTPKEPA--PTTPKGTAPTTLK----EPAPTTPKKPAPKE 708



 Score = 32.3 bits (72), Expect = 0.31
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 6/103 (5%)

Query: 118 ETKPGASKVATKTKATGASKKLKK-ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
           E  P  +K A  T    A    KK A    K+   T  K   P   ++ +   K+P    
Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 385

Query: 177 PKKVA----KSPAKAKAVKPKAAKARVTKPKTAK-PKKAAPKK 214
           PK+ A    K PA     +P     +   P T K P    PK+
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 27/114 (23%), Positives = 39/114 (34%), Gaps = 11/114 (9%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNP-- 169
           KK +  E  P  +K  T T +   +    K T  +      P   KKPA T   +  P  
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 761

Query: 170 ---------KKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
                    K+P T+       +P  +    PKA +    +P     K  A  K
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 815



 Score = 30.8 bits (68), Expect = 0.91
 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 4/103 (3%)

Query: 112 KKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKK 171
           KK +    K  A     +T  T   KKL   T   K +  TP+K         +   P++
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPT-TPKKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEE 562

Query: 172 PKTVKPKKVAKSPAKAKAVKPKAAKARVT--KPKTAKPKKAAP 212
           P    P++ A +  KA A       A  T  +P    PK+ AP
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 26/107 (24%), Positives = 36/107 (33%), Gaps = 10/107 (9%)

Query: 116 SVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTV 175
           S  T P      T  +    + K    T   K +  TPK+         +    KKP   
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510

Query: 176 KPKKVA------KSPAKAKAVKP----KAAKARVTKPKTAKPKKAAP 212
            PK+ A       +P   K + P    K A     KP    P++ AP
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 47/210 (22%), Positives = 67/210 (31%), Gaps = 14/210 (6%)

Query: 3   ETVPPAPAASA--APEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60
           E  P  P A+A   P++P        P + A  + K+PA  +  E    A ++ K     
Sbjct: 570 EPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPT 622

Query: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFK---LNKKASSV 117
           +L              E   +  K    +   K      KGT  +   +      K  + 
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682

Query: 118 ETKPGASKVATKTKATGASKK-LKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVK 176
            T  G +    K  A    KK   K    +     T   + KPA T      P  PK   
Sbjct: 683 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742

Query: 177 PKKVAKSPAKAKAVKPKAAKARVTKPKTAK 206
           P    K PA      P    + V+ P T K
Sbjct: 743 P-TTPKKPAPTTPETPPPTTSEVSTPTTTK 771



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 15/115 (13%)

Query: 100 KGTGASGSFKLNKKASSVETKPGASKVA-TKTKATGASKKLKKATGASKKSVKTPKKAKK 158
           KGT  +    L + A +   KP   ++A T TK   ++   K A    K++   P   K+
Sbjct: 686 KGTAPT---TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKE 740

Query: 159 PAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPK 213
           PA T      PKKP    P+     P  ++   P   K   T  K+  P ++ P+
Sbjct: 741 PAPT-----TPKKPAPTTPE--TPPPTTSEVSTPTTTKEPTTIHKS--PDESTPE 786



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 8/100 (8%)

Query: 118 ETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAAT---RKSSKNPKKPKT 174
           E  P   K  T T     +   K+    + K    P   KKPA T     +   PK+P  
Sbjct: 357 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPTTPKEPAP 415

Query: 175 VKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKP--KKAAP 212
              K+   SP   K   P   K+  T  K   P   K+AP
Sbjct: 416 TTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.298    0.113    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,605,516
Number of Sequences: 37866
Number of extensions: 318502
Number of successful extensions: 5768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 438
Number of HSP's that attempted gapping in prelim test: 3119
Number of HSP's gapped (non-prelim): 1927
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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