BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|48526516 solute carrier family 22, member 23 isoform b [Homo sapiens] (405 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 816 0.0 gi|48526516 solute carrier family 22, member 23 isoform b [Homo ... 816 0.0 gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 213 2e-55 gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 213 3e-55 gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 208 8e-54 gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 204 1e-52 gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo sap... 101 1e-21 gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 93 5e-19 gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 91 1e-18 gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 91 2e-18 gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 89 7e-18 gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 89 7e-18 gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 84 3e-16 gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 84 3e-16 gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 83 4e-16 gi|166064021 solute carrier family 22 (organic anion transporter... 81 1e-15 gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 80 4e-15 gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 77 4e-14 gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 77 4e-14 gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 76 5e-14 gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 76 5e-14 gi|42542386 solute carrier family 22 (organic anion/cation trans... 75 1e-13 gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 74 2e-13 gi|157426885 organic cation transporter like 4 [Homo sapiens] 72 1e-12 gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 70 3e-12 gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 69 8e-12 gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 69 8e-12 gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens] 66 6e-11 gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 60 4e-09 gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 59 6e-09 >gi|170650643 solute carrier family 22, member 23 isoform a [Homo sapiens] Length = 686 Score = 816 bits (2109), Expect = 0.0 Identities = 405/405 (100%), Positives = 405/405 (100%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD Sbjct: 282 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 341 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV Sbjct: 342 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 401 Query: 121 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 180 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL Sbjct: 402 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 461 Query: 181 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 240 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS Sbjct: 462 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 521 Query: 241 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 300 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF Sbjct: 522 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 581 Query: 301 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 360 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL Sbjct: 582 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 641 Query: 361 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 405 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM Sbjct: 642 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 686 >gi|48526516 solute carrier family 22, member 23 isoform b [Homo sapiens] Length = 405 Score = 816 bits (2109), Expect = 0.0 Identities = 405/405 (100%), Positives = 405/405 (100%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD Sbjct: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV Sbjct: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120 Query: 121 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 180 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL Sbjct: 121 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 180 Query: 181 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 240 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS Sbjct: 181 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 240 Query: 241 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 300 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF Sbjct: 241 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 300 Query: 301 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 360 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL Sbjct: 301 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 360 Query: 361 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 405 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM Sbjct: 361 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 405 >gi|21361834 solute carrier family 22, member 17 isoform a [Homo sapiens] Length = 538 Score = 213 bits (542), Expect = 2e-55 Identities = 134/392 (34%), Positives = 201/392 (51%), Gaps = 38/392 (9%) Query: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64 LRF GF LAG+ L +Y +R+ELC P +R + + V + G FL GLA + +DW+ L Sbjct: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFL 216 Query: 65 QALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIP 122 Q +I P +L L Y W +F ES RWL+ +Q E A+ ++ ++NR P G + G Sbjct: 217 QRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG--- 271 Query: 123 ELEKELSRRPKKVC---------IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMG 173 E +E + + C ++ RN+WKN+++L + + I HC+ G Sbjct: 272 EEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGG 331 Query: 174 HEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLL 233 +FY + A ++C+ + V V GRRG LLL M LT +ASL+ LGL Sbjct: 332 GSPS-----DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW 386 Query: 234 NLIGKYSQHP--------DSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTV 285 + +HP + + + FS++G+F+S A LS AE+ PT Sbjct: 387 DC-----EHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 441 Query: 286 IRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNL 345 +R GLGL++A G L+ P LH G FL H++ A C L+CI+ I+LLPE++ + L Sbjct: 442 VRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLL 501 Query: 346 PENISNGEHYTRQPLL----PHKKGEQPLLLT 373 PE + +GE R LL P + PLL T Sbjct: 502 PEVLRDGELCRRPSLLRQPPPTRCDHVPLLAT 533 >gi|63999576 solute carrier family 22, member 17 isoform b [Homo sapiens] Length = 520 Score = 213 bits (541), Expect = 3e-55 Identities = 133/384 (34%), Positives = 197/384 (51%), Gaps = 40/384 (10%) Query: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64 LRF GF LAG+ L +Y +R+ELC P +R + + V + G FL GLA + +DW+ L Sbjct: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFL 216 Query: 65 QALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIP 122 Q +I P +L L Y W +F ES RWL+ +Q E A+ ++ ++NR P G + G Sbjct: 217 QRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG--- 271 Query: 123 ELEKELSRRPKKVC---------IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMG 173 E +E + + C ++ RN+WKN+++L + + I HC+ G Sbjct: 272 EEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGG 331 Query: 174 HEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLL 233 +FY + A ++C+ + V V GRRG LLL M LT +ASL+ LGL Sbjct: 332 GSPS-----DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW 386 Query: 234 NLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGL 293 D + + FS++G+F+S A LS AE+ PT +R GLGL Sbjct: 387 ---------------DYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGL 431 Query: 294 VLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353 ++A G L+ P LH G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE Sbjct: 432 IMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 491 Query: 354 HYTRQPLL----PHKKGEQPLLLT 373 R LL P + PLL T Sbjct: 492 LCRRPSLLRQPPPTRCDHVPLLAT 515 >gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1 [Homo sapiens] Length = 558 Score = 208 bits (529), Expect = 8e-54 Identities = 127/367 (34%), Positives = 196/367 (53%), Gaps = 31/367 (8%) Query: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64 LR G LAG +L LY R+ELC P R +M A ++ G L+PGLAAL +DW++L Sbjct: 186 LRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLL 245 Query: 65 QALIICPFLLMLLYW---SIFPESLRWLMATQQFESAKRLILHFTQKNRMNP-----EGD 116 Q L L+LL+W ++FPES WL+AT Q A++++ F + + + P E + Sbjct: 246 QGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEEN 305 Query: 117 IKGVIPELEKELSR--RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGH 174 EL +R +P+ + ++ TR W+N ++L +SL G GI F RS+ Sbjct: 306 SLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASFRRSL--- 362 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLN 234 P + FY Y+ A + + + + + GRR LLL ++T LASLL L Sbjct: 363 ---APQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQ 419 Query: 235 LIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLV 294 + ++ + S++G+ AS AV +LS F AE+ PTVIR GLGLV Sbjct: 420 YLPGWTV---------------LFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLV 464 Query: 295 LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEH 354 L + G P+ LH ++G+FL ++FA ++ ++C+LLLPESR + LP+++ + + Sbjct: 465 LGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADR 524 Query: 355 YTRQPLL 361 R PLL Sbjct: 525 LRRSPLL 531 >gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6 [Homo sapiens] Length = 560 Score = 204 bits (519), Expect = 1e-52 Identities = 126/367 (34%), Positives = 195/367 (53%), Gaps = 31/367 (8%) Query: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64 LR G LAG +L LY R+ELC P R +M A ++ G L+PGLAAL +DW++L Sbjct: 188 LRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLL 247 Query: 65 QALIICPFLLMLLYW---SIFPESLRWLMATQQFESAKRLILHFTQKNRMNP-----EGD 116 Q L L+LL+W ++FPES WL+AT Q A++++ F + + + P E + Sbjct: 248 QGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEEN 307 Query: 117 IKGVIPELEKELSR--RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGH 174 EL +R +P+ + ++ TR W+N ++L +SL G GI F RS+ Sbjct: 308 SLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASFRRSL--- 364 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLN 234 P + FY Y+ A + + + + + GRR LLL ++T LASLL L Sbjct: 365 ---APQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQ 421 Query: 235 LIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLV 294 + ++ + S++G+ AS AV +LS F AE+ PTVIR GLGLV Sbjct: 422 YLPGWTV---------------LFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLV 466 Query: 295 LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEH 354 L + G + LH ++G+FL ++FA ++ ++C+LLLPESR + LP+++ + + Sbjct: 467 LGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADR 526 Query: 355 YTRQPLL 361 R PLL Sbjct: 527 LRRSPLL 533 >gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo sapiens] Length = 495 Score = 101 bits (251), Expect = 1e-21 Identities = 84/278 (30%), Positives = 131/278 (47%), Gaps = 34/278 (12%) Query: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64 LR G LAG +L LY R+ELC P R +M A ++ G L+PGLAAL +DW++L Sbjct: 186 LRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLL 245 Query: 65 QALIICPFLLMLLYW---SIFPESLRWLMATQQFESAKRLILHFTQKNRMNP-----EGD 116 Q L L+LL+W ++FPES WL+AT Q A++++ F + + + P E + Sbjct: 246 QGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEEN 305 Query: 117 IKGVIPELEKELSR--RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGH 174 EL +R +P+ + ++ TR W+N ++L +SL G GI ++ G Sbjct: 306 SLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIR----ANLPGW 361 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVR-----------FLGRRGGLL------- 216 V + A +A +L + V+R FLG+ GLL Sbjct: 362 TVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGLLDTLHGRQ 421 Query: 217 -LFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKD 253 F+ ASL L LL ++ + G+ S++D Sbjct: 422 GFFLQQVVFASLAVLALLCVL-LLPESRSRGLPQSLQD 458 Score = 97.8 bits (242), Expect = 2e-20 Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 7/134 (5%) Query: 228 LQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIR 287 L LG +L+G G+ ++ + S++G+ AS AV +LS F AE+ PTVIR Sbjct: 342 LILGFSSLVG-------GGIRANLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIR 394 Query: 288 CGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPE 347 GLGLVL + G + LH ++G+FL ++FA ++ ++C+LLLPESR + LP+ Sbjct: 395 GAGLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQ 454 Query: 348 NISNGEHYTRQPLL 361 ++ + + R PLL Sbjct: 455 SLQDADRLRRSPLL 468 >gi|24497499 solute carrier family 22 member 8 [Homo sapiens] Length = 542 Score = 92.8 bits (229), Expect = 5e-19 Identities = 90/375 (24%), Positives = 166/375 (44%), Gaps = 35/375 (9%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ RF GF ++GI L+ L +E P R +++ + GQF++PGLA Sbjct: 175 IYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQ 234 Query: 61 WQVLQALIICPFLLMLL--YWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD-- 116 W+ LQ + PF + L +W+ PES+RWL+ + + A +++ N EG+ Sbjct: 235 WRWLQLTVSIPFFVFFLSSWWT--PESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERL 292 Query: 117 -IKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHE 175 ++ + L+KE+S K + L + + C+ SL + + MG E Sbjct: 293 SLEELKLNLQKEISLAKAKYTASDLFRIPMLRR--MTFCL-SLAWFATGFAYYSLAMGVE 349 Query: 176 ---VKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGL 232 V + +L+ + A + L+ +LGR ++L A L Sbjct: 350 EFGVNLYILQIIFGGVDVPAKFITILSLS------YLGRHTTQAAALLLAGGAIL----A 399 Query: 233 LNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLG 292 L + Q + ++ K S +FS + ++ S E+ PTVIR G+G Sbjct: 400 LTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTS------------ELYPTVIRQTGMG 447 Query: 293 LVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNG 352 + G + +P++++ + F+ +II+ L+ L LPE+ +Q LPE I + Sbjct: 448 VSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDL 507 Query: 353 EHYTRQPLLPHKKGE 367 E+++ + P ++ E Sbjct: 508 ENWSLRAKKPKQEPE 522 >gi|148664184 solute carrier family 22, member 10 [Homo sapiens] Length = 541 Score = 91.3 bits (225), Expect = 1e-18 Identities = 91/362 (25%), Positives = 160/362 (44%), Gaps = 35/362 (9%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFLMPGLAALCR 59 ++ LRF GF + II++ +L I E P + ++ +++S GQ ++ GLA + R Sbjct: 198 VYCVLRFLAGFS-SMIIISNNSLPITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFR 256 Query: 60 DWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRM-NPEG--D 116 DWQ L + PF + L ES RWL+ T + + + + + N + N E + Sbjct: 257 DWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEETLN 316 Query: 117 IKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLC----VNSLTGYGIHHCFARSMM 172 I+ V +++EL K + + ++ K I +L N++ YG ++ Sbjct: 317 IEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFANTIPFYGT----MVNLQ 372 Query: 173 GHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGL 232 + LL+ Y A +V CLA+ + + +GRR +LFM L L+ L Sbjct: 373 HVGSNIFLLQVLYG-----AVALIVRCLAL-LTLNHMGRRISQILFMFLVGLSILAN--- 423 Query: 233 LNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLG 292 + K Q +A + +G+ S A S E+ PTV+R G Sbjct: 424 -TFVPKEMQ------------TLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASG 470 Query: 293 LVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNG 352 + L ++ G AP++ L II+ +I + + LLPE+++ LP+ I + Sbjct: 471 IDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDV 530 Query: 353 EH 354 E+ Sbjct: 531 EN 532 >gi|24497476 solute carrier family 22 member 6 isoform b [Homo sapiens] Length = 550 Score = 90.5 bits (223), Expect = 2e-18 Identities = 81/389 (20%), Positives = 165/389 (42%), Gaps = 31/389 (7%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ R G LAGI L L +E P R + + +V GQFL+ G+A Sbjct: 187 IYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH 246 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DI 117 W+ LQ L+ PF +Y F ES RW ++ + + R + + N EG + Sbjct: 247 WRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSM 306 Query: 118 KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGH 174 + + L+KEL+ + ++++ L + LC++ L T + ++ + G Sbjct: 307 EVLRASLQKELTMGKGQASAMELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGF 363 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLN 234 V + L++ + ++ L + L +V+ LGRR + ++L + LL Sbjct: 364 GVSIYLIQVIF------GAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILL------ 411 Query: 235 LIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLV 294 +G+ + + +++G A + + E+ PT+IR G+G+ Sbjct: 412 ----------NGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMG 461 Query: 295 LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEH 354 A G + +P++ + + + I+ + +LLPE+ Q LP+ + + E Sbjct: 462 STMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLES 521 Query: 355 YTRQPLLPHKKGEQPLLLTNAELKDYSGL 383 + ++ ++ ++ A ++ +GL Sbjct: 522 RKGKQTRQQQEHQKYMVPLQASAQEKNGL 550 >gi|238814326 solute carrier family 22, member 20 [Homo sapiens] Length = 555 Score = 89.0 bits (219), Expect = 7e-18 Identities = 83/360 (23%), Positives = 150/360 (41%), Gaps = 25/360 (6%) Query: 2 FSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDW 61 + RF G +GIIL +L +E P R + ++ + GQ ++ G+A L R W Sbjct: 190 YCVFRFLMGMTFSGIILNSVSLVVEWMPTRGRTVAGILLGYSFTLGQLILAGVAYLIRPW 249 Query: 62 QVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVI 121 + LQ I PFL+ LY PES RWL+ + + A + + N EG+ Sbjct: 250 RCLQFAISAPFLIFFLYSWWLPESSRWLLLHGKSQLAVQNLQKVAAMNGRKEEGE----- 304 Query: 122 PELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLL 181 L KE+ + V + ++ + +T + F+ S+ + + + L Sbjct: 305 -RLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKVTCCLMVIWFSNSVAYYGLAMDLQ 363 Query: 182 ENFYADYYTTASIALVSCLAMCVVVR---FLGRRGGLLLFMILTALASLLQLGLLNLIGK 238 + + Y A +++ AM V ++GRR + F+IL L + + + + Sbjct: 364 KFGLSLYLVQALFGIINTPAMLVATATMIYVGRRATVASFLILAGLMVIANM----FVPE 419 Query: 239 YSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASA 298 +Q + + K + +F V +F E+ PT IR G+G A Sbjct: 420 GTQILCTAQAALGKGCLASSFICVYLFT------------GELYPTEIRQMGMGFASVHA 467 Query: 299 GFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQ 358 G LTAP++ + L + F ++ + + +L E+R+ L E I+ E ++ Sbjct: 468 RLGGLTAPLVTTLGEYSTILPPVSFGATAILAGLAVCVLTETRNMPLVETIAAMERRVKE 527 >gi|20070188 solute carrier family 22 member 6 isoform a [Homo sapiens] Length = 563 Score = 89.0 bits (219), Expect = 7e-18 Identities = 78/359 (21%), Positives = 152/359 (42%), Gaps = 31/359 (8%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ R G LAGI L L +E P R + + +V GQFL+ G+A Sbjct: 187 IYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH 246 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DI 117 W+ LQ L+ PF +Y F ES RW ++ + + R + + N EG + Sbjct: 247 WRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSM 306 Query: 118 KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGH 174 + + L+KEL+ + ++++ L + LC++ L T + ++ + G Sbjct: 307 EVLRASLQKELTMGKGQASAMELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGF 363 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLN 234 V + L++ + ++ L + L +V+ LGRR + ++L + LL Sbjct: 364 GVSIYLIQVIF------GAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILL------ 411 Query: 235 LIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLV 294 +G+ + + +++G A + + E+ PT+IR G+G+ Sbjct: 412 ----------NGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMG 461 Query: 295 LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353 A G + +P++ + + + I+ + +LLPE+ Q LP+ + + E Sbjct: 462 STMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520 >gi|90669191 solute carrier family 22 member 7 isoform b [Homo sapiens] Length = 548 Score = 83.6 bits (205), Expect = 3e-16 Identities = 94/363 (25%), Positives = 149/363 (41%), Gaps = 41/363 (11%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 MF+ R G LAG + + L +E R + +++S G L+ + L RD Sbjct: 197 MFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD 256 Query: 61 WQVLQALIICPFL--LMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN-------RM 111 W+ L + P ++ L+W PES RWL+ + A R +LH + N Sbjct: 257 WRWLLLAVTLPCAPGILSLWW--VPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSF 314 Query: 112 NPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSM 171 + E K E + RRP + + + R+ I + CV + +G++ S Sbjct: 315 SQEAVSKVAAGE---RVVRRPSYLDLFRTPRLRH----ISLCCV--VVWFGVNF----SY 361 Query: 172 MGHEVKVPLLE-NFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 230 G + V L N Y ++ L S L + + VR+ GRR L T L + L Sbjct: 362 YGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRR----LTQAGTLLGTALAF 417 Query: 231 GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGG 290 G L+ S +S +++G S A + + F +E+ PTV+R G Sbjct: 418 GTRLLVS------------SDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTG 465 Query: 291 LGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIS 350 +GL G AP+ L + L + + L+ LLLPE+R LPE I Sbjct: 466 MGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQ 525 Query: 351 NGE 353 + E Sbjct: 526 DVE 528 >gi|24497497 solute carrier family 22 member 7 isoform a [Homo sapiens] Length = 546 Score = 83.6 bits (205), Expect = 3e-16 Identities = 94/363 (25%), Positives = 149/363 (41%), Gaps = 41/363 (11%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 MF+ R G LAG + + L +E R + +++S G L+ + L RD Sbjct: 195 MFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD 254 Query: 61 WQVLQALIICPFL--LMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN-------RM 111 W+ L + P ++ L+W PES RWL+ + A R +LH + N Sbjct: 255 WRWLLLAVTLPCAPGILSLWW--VPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSF 312 Query: 112 NPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSM 171 + E K E + RRP + + + R+ I + CV + +G++ S Sbjct: 313 SQEAVSKVAAGE---RVVRRPSYLDLFRTPRLRH----ISLCCV--VVWFGVNF----SY 359 Query: 172 MGHEVKVPLLE-NFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 230 G + V L N Y ++ L S L + + VR+ GRR L T L + L Sbjct: 360 YGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRR----LTQAGTLLGTALAF 415 Query: 231 GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGG 290 G L+ S +S +++G S A + + F +E+ PTV+R G Sbjct: 416 GTRLLVS------------SDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTG 463 Query: 291 LGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIS 350 +GL G AP+ L + L + + L+ LLLPE+R LPE I Sbjct: 464 MGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQ 523 Query: 351 NGE 353 + E Sbjct: 524 DVE 526 >gi|11415038 solute carrier family 22 member 3 [Homo sapiens] Length = 556 Score = 83.2 bits (204), Expect = 4e-16 Identities = 84/359 (23%), Positives = 154/359 (42%), Gaps = 38/359 (10%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 +F RF +G G +T Y + E+ +R ++ +V G ++PG+A + Sbjct: 207 VFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPN 266 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120 WQ +Q I P L LLY+ + PES RWL+ ++ + A +++ + N + Sbjct: 267 WQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNY-SE 325 Query: 121 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 180 I ++E+S + +V T + K ++L T ++ G +++ + Sbjct: 326 ITVTDEEVS----NPSFLDLVRTPQMRKCTLILMFAWFTSAVVY-------QGLVMRLGI 374 Query: 181 L-ENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKY 239 + N Y D++ + + L L + + + LGRR L AS + G+ L+ + Sbjct: 375 IGGNLYIDFFISGVVELPGALLILLTIERLGRR--------LPFAASNIVAGVACLVTAF 426 Query: 240 SQHPDSGMSDSV----KDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVL 295 + + +V + ++AF IV + S E+ PT +R G+ L Sbjct: 427 LPEGIAWLRTTVATLGRLGITMAFEIVYLVNS------------ELYPTTLRNFGVSLCS 474 Query: 296 ASAGFGMLTAPIIELHNQKGYF-LHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353 FG + AP + + L IIF IC ++LLPE++ LPE + + E Sbjct: 475 GLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVE 533 >gi|166064021 solute carrier family 22 (organic anion transporter), member 13 [Homo sapiens] Length = 551 Score = 81.3 bits (199), Expect = 1e-15 Identities = 90/381 (23%), Positives = 161/381 (42%), Gaps = 56/381 (14%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ LRF +AG+ + L E P R ++A GQ ++ GLA R+ Sbjct: 190 LYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFRN 249 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNR--MNPEGDIK 118 W++LQ P LL+ Y+ PES RWL+ + + A +LI NR ++PE + Sbjct: 250 WRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPE-LMN 308 Query: 119 GVIPEL------EKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMM 172 ++PE +L R P+ + ++ V V+SL YG+ S+ Sbjct: 309 QLVPEKTGPSGNALDLFRHPQLRKVTLII--------FCVWFVDSLGYYGL------SLQ 354 Query: 173 GHEVKVPLLENFYADYYTTASI-----ALVSCLAMCVVVRFLGRRGGLLLFMILTALASL 227 + +F D Y T I C ++ ++ RF GR+ L ++L L + Sbjct: 355 --------VGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRF-GRKWSQLGTLVLGGLMCI 405 Query: 228 LQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIR 287 + + + + ++VG A+ A ++S + AE+ PT++R Sbjct: 406 IIIFI----------------PADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILR 449 Query: 288 CGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPE 347 G+GLV + G + P++ L + L +I+ ++ + LLPE+ Q L + Sbjct: 450 QTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKD 509 Query: 348 NISN---GEHYTRQPLLPHKK 365 + + G H +P +K Sbjct: 510 TLQDLELGPHPRSPKSVPSEK 530 >gi|24497490 solute carrier family 22 member 4 [Homo sapiens] Length = 551 Score = 79.7 bits (195), Expect = 4e-15 Identities = 87/362 (24%), Positives = 148/362 (40%), Gaps = 50/362 (13%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITM--VASFVAMAGQFLMPGLAALC 58 MF+ L G + + L E+ R + + V +F A+ G L+P A Sbjct: 195 MFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAV-GYMLLPLFAYFI 253 Query: 59 RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIK 118 RDW++L + P +L + W PES RWL++ ++F A+ +I + N + I Sbjct: 254 RDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIF 313 Query: 119 GVIPELEKELSRRPKKVCIVKVVGTRNL-WKNIVVLCVNSLTGYGIHHCFARSMMGHEVK 177 + EL + +K I+ + TRN+ I+ L + LT G FA S+ Sbjct: 314 DSVEELN---PLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGY---FALSLDAPN-- 365 Query: 178 VPLLENFYADYYTTASIALVSCLAMCVVVRFLGRR----------GGLLLFMILTALASL 227 L + Y + + +A I + + + +++R L RR GG+LLF+ L + Sbjct: 366 --LHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYY 423 Query: 228 LQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIR 287 SI ++G F + S+ F AE+ PT++R Sbjct: 424 F--------------------------LSIGLVMLGKFGITSAFSMLYVFTAELYPTLVR 457 Query: 288 CGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPE 347 +G+ ++ G + AP L +I+ T++ I L PES LPE Sbjct: 458 NMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPE 517 Query: 348 NI 349 + Sbjct: 518 TL 519 >gi|211059435 solute carrier family 22, member 24 [Homo sapiens] Length = 551 Score = 76.6 bits (187), Expect = 4e-14 Identities = 83/361 (22%), Positives = 135/361 (37%), Gaps = 33/361 (9%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ LRF GF I+ + L +E P R M MV GQ L+ GLA +D Sbjct: 198 VYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQD 257 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAK---RLILHFTQKNRMNPEGDI 117 W +LQ + P +++ L ES RWL+ Q + R + H K Sbjct: 258 WHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTT 317 Query: 118 KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVK 177 + V ++KEL K I + L + LC F R + Sbjct: 318 ELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLC------------FVR----FAIT 361 Query: 178 VPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLF----MILTALASLLQLGLL 233 VP + ++++L L C V F R LL ++ + +GL Sbjct: 362 VPFYGLILNLQHLGSNVSLFQIL--CGAVTFTARCVSLLTLNHMGRRISQILFTFPVGLF 419 Query: 234 NLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGL 293 L+ + + + +G+ + A + + E+ PT++R G+ Sbjct: 420 ILVNTFLPQE--------MQILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGI 471 Query: 294 VLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353 S G AP++ L I + ++ + ILLLPE+RD LP I + E Sbjct: 472 NAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVILLLPETRDLPLPNTIQDVE 531 Query: 354 H 354 + Sbjct: 532 N 532 >gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] Length = 553 Score = 76.6 bits (187), Expect = 4e-14 Identities = 79/361 (21%), Positives = 152/361 (42%), Gaps = 39/361 (10%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ RF F +AG+++ L +E R ++ + S G L +A RD Sbjct: 198 VYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRD 257 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120 W +LQ ++ PF L LY ES RWL+ T + + + + +N +G ++ Sbjct: 258 WTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAA---INGKGAVQDT 314 Query: 121 I-PEL-------EKELSRRPKKV-CIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSM 171 + PE+ E + + P + ++++ G R C+++L + F + Sbjct: 315 LTPEVLLSAMREELSMGQPPASLGTLLRMPGLR------FRTCISTLCWFA----FGFTF 364 Query: 172 MGHEVKVPLL-ENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 230 G + + L N + + + + + +++ LGRR T ASLL Sbjct: 365 FGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRP--------TLAASLLLA 416 Query: 231 GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGG 290 GL L H + A +++G+ A + + +E+ PTV+R Sbjct: 417 GLCILANTLVPHEMGALRS--------ALAVLGLGGVGAAFTCITIYSSELFPTVLRMTA 468 Query: 291 LGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIS 350 +GL +A G + P++ L G +L +++ ++ + LLLPE++ LP+ I Sbjct: 469 VGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQ 528 Query: 351 N 351 + Sbjct: 529 D 529 >gi|4506999 solute carrier family 22 member 1 isoform a [Homo sapiens] Length = 554 Score = 76.3 bits (186), Expect = 5e-14 Identities = 80/354 (22%), Positives = 139/354 (39%), Gaps = 26/354 (7%) Query: 6 RFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQ 65 R +G G + Y L E G R + ++ G + GLA W+ LQ Sbjct: 206 RLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQ 265 Query: 66 ALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELE 125 + P L LLY+ PES RWL++ ++ A +++ H QKN P D+K + LE Sbjct: 266 LAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLK--MLSLE 323 Query: 126 KELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFY 185 ++++ + + T L K +L T ++ M N Y Sbjct: 324 EDVTEK-LSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATS------GNLY 376 Query: 186 ADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDS 245 D+ +A + + + + +GR + + +L A L+ + + PD Sbjct: 377 LDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFI---------SPDL 427 Query: 246 GMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTA 305 +I VG + AE+ PT +R G+ + + G + Sbjct: 428 HW-------LNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT 480 Query: 306 PIIELHNQKGY-FLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQ 358 P I ++ + L I+FA L+ LLLPE++ LPE + + E+ R+ Sbjct: 481 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRK 534 >gi|4507005 solute carrier family 22 member 5 [Homo sapiens] Length = 557 Score = 76.3 bits (186), Expect = 5e-14 Identities = 80/351 (22%), Positives = 150/351 (42%), Gaps = 26/351 (7%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMA-GQFLMPGLAALCR 59 MF L G + + L E+ R + + + + A G ++P A R Sbjct: 195 MFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIR 254 Query: 60 DWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKG 119 DW++L + P +L + W PES RWL++ +FE A+ +I + N + I Sbjct: 255 DWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFD 314 Query: 120 VIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVP 179 EL+ S++ + I+ ++ T N+ ++ + +T + G + P Sbjct: 315 P-SELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMT-------ISVGYFGLSLDTP 366 Query: 180 LLE-NFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGK 238 L + + + + +A + + + + +++++L RR ++A+ L LG L+ Sbjct: 367 NLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR---------YSMATALFLGGSVLLFM 417 Query: 239 YSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASA 298 PD +V +VG F A S+ + AE+ PTV+R G+G+ ++ Sbjct: 418 QLVPPDLYYLATV-------LVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTAS 470 Query: 299 GFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENI 349 G + +P FL +I+ T++ I L LPES LP+ I Sbjct: 471 RLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTI 521 >gi|42542386 solute carrier family 22 (organic anion/cation transporter), member 9 [Homo sapiens] Length = 553 Score = 74.7 bits (182), Expect = 1e-13 Identities = 85/387 (21%), Positives = 155/387 (40%), Gaps = 56/387 (14%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIE--------------LCPPGKRFMITMVASFVAMA 46 ++ +LRF G +I L E +CP G FM Sbjct: 198 IYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAFMT---------- 247 Query: 47 GQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFT 106 + GLA RDW +LQ ++ P+ ++ L S ES RWL+ + E + + Sbjct: 248 ----LAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAA 303 Query: 107 QKNRMNPEGD---IKGVIPELEKEL-SRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYG 162 ++ M D ++ + ++KEL + + KK + +++ N+ K I +L + Sbjct: 304 HRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFM 363 Query: 163 IHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILT 222 + + V LL+ + A I L +C+A + +++ RR +L M L Sbjct: 364 AYFGLNLHVQHLGNNVFLLQTLFG-----AVILLANCVAPWAL-KYMNRRASQMLLMFLL 417 Query: 223 ALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEIT 282 A+ L + + + + + +G+ AS +L+ E+ Sbjct: 418 AICLLAIIFVPQEMQTLRE----------------VLATLGLGASALANTLAFAHGNEVI 461 Query: 283 PTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRD 342 PT+IR +G+ A AP++ + + L II+ I LLLPE+R+ Sbjct: 462 PTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRN 521 Query: 343 QNLPENISNGEHYTRQPLLPHKKGEQP 369 + L + I + ++ + P P K E P Sbjct: 522 KPLFDTIQDEKNERKDPREP--KQEDP 546 >gi|8923870 solute carrier family 22 member 11 [Homo sapiens] Length = 550 Score = 74.3 bits (181), Expect = 2e-13 Identities = 87/368 (23%), Positives = 155/368 (42%), Gaps = 49/368 (13%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ LRF F +AGI L+ L +E +R + V AGQ + GLA RD Sbjct: 195 IYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRD 254 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLM-------ATQQFESAKRLILHFTQKNRMNP 113 W+ LQ PF + L PES RWL+ A Q+ R+ H KN Sbjct: 255 WRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNL--- 311 Query: 114 EGDIKGVIPELEKEL--SRRPKKVCIVKVVGTRNLWKNIVVLCVN---SLTGYGIHHCFA 168 I+ ++ +++E+ ++ P+ V + V W++ +L VN ++ YG+ F Sbjct: 312 --TIEVLMSSVKEEVASAKEPRSVLDLFCVPVLR-WRSCAMLVVNFSLLISYYGL--VFD 366 Query: 169 RSMMGHEVKVPLLENFY--ADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALAS 226 +G ++ LL+ + D+ A+ AL ++ FLGRR + LA Sbjct: 367 LQSLGRDIF--LLQALFGAVDFLGRATTAL--------LLSFLGRRTIQAGSQAMAGLAI 416 Query: 227 LLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVI 286 L + L+ + Q + F+++G + + AE+ PT + Sbjct: 417 LANM----LVPQDLQ------------TLRVVFAVLGKGCFGISLTCLTIYKAELFPTPV 460 Query: 287 RCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLI-CIICILLLPESRDQNL 345 R G++ G + P+I + Q L +++ ++ ++ + LPE++ L Sbjct: 461 RMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPL 520 Query: 346 PENISNGE 353 P+ I + E Sbjct: 521 PDTIQDLE 528 >gi|157426885 organic cation transporter like 4 [Homo sapiens] Length = 594 Score = 71.6 bits (174), Expect = 1e-12 Identities = 91/320 (28%), Positives = 146/320 (45%), Gaps = 43/320 (13%) Query: 47 GQFLMPGLAALCRDWQVL---QALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLIL 103 G L+ G+A WQ+L +++ PF+ + W I PES RWLM + + AK+++ Sbjct: 282 GAVLLTGIAYSLPHWQLLFLVGGILVIPFISYI--W-ILPESPRWLMMKGKVKEAKQVLC 338 Query: 104 HFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVG---TRNLWK-NIVVLCVNSLT 159 + N+ K + L EL KKV V+ R L K +V+ CV Sbjct: 339 YAASVNK-------KTIPSNLLDELQLPRKKVTRASVLDFCKNRQLCKVTLVMSCVWFTV 391 Query: 160 GYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCV-VVRFLGRRGGLLLF 218 Y F S+ E+ V + + SI V C+ +++ +GR+ L + Sbjct: 392 SYTY---FTLSLRMRELGVSVHFR-----HVVPSIMEVPARLCCIFLLQQIGRKWSLAVT 443 Query: 219 MILTALASLLQL----GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLS 274 ++ + LL L G L K+ + P + + +I ++ F+ A ++ Sbjct: 444 LLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKS-----MTILVLMLREFSLAATVTVF 498 Query: 275 VFFCAEITPTVIRCGGLGLV-LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIIC 333 + AE+ PTV+R GLGLV LAS +L+ II +Q L IF CC L + Sbjct: 499 FLYTAELLPTVLRATGLGLVSLASVAGAILSLTII---SQTPSLLP--IFLCCVLAIVAF 553 Query: 334 IL--LLPESRDQNLPENISN 351 L LLPE+RDQ L E++++ Sbjct: 554 SLSSLLPETRDQPLSESLNH 573 >gi|4507001 solute carrier family 22 member 2 [Homo sapiens] Length = 555 Score = 70.1 bits (170), Expect = 3e-12 Identities = 78/348 (22%), Positives = 141/348 (40%), Gaps = 38/348 (10%) Query: 31 GKRFMITMVASFVAMA---GQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLR 87 G+R+ T V F +A G ++ G+A W+ LQ + P LLY+ PES R Sbjct: 230 GRRYRRT-VGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPR 288 Query: 88 WLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLW 147 WL++ + A R+I H +KN + ++ + LE+E ++ + +V T + Sbjct: 289 WLISQNKNAEAMRIIKHIAKKNGKSLPASLQRL--RLEEETGKKLNP-SFLDLVRTPQIR 345 Query: 148 KNIVVLCVNSLTGYGIHHCFARSM--MGHEVKVPLLENFYADYYTTASIALVSCLAMCVV 205 K+ ++L N T ++ M G +N Y D++ +A + + + + Sbjct: 346 KHTMILMYNWFTSSVLYQGLIMHMGLAG--------DNIYLDFFYSALVEFPAAFMIILT 397 Query: 206 VRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMF 265 + +GRR ++ A L + + + I S +G Sbjct: 398 IDRIGRRYPWAASNMVAGAACLASVFIPGDL----------------QWLKIIISCLGRM 441 Query: 266 ASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYF-LHHIIFA 324 + AE+ PT IR G+ + + G + P + + L ++F Sbjct: 442 GITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFG 501 Query: 325 CCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLL 372 L+ +LLLPE++ + LPE I E+ R P K E+ + L Sbjct: 502 VLGLVAGGLVLLLPETKGKALPETIEEAENMQR----PRKNKEKMIYL 545 >gi|24497480 solute carrier family 22 member 6 isoform d [Homo sapiens] Length = 519 Score = 68.9 bits (167), Expect = 8e-12 Identities = 56/234 (23%), Positives = 103/234 (44%), Gaps = 15/234 (6%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ R G LAGI L L +E P R + + +V GQFL+ G+A Sbjct: 187 IYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH 246 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DI 117 W+ LQ L+ PF +Y F ES RW ++ + + R + + N EG + Sbjct: 247 WRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSM 306 Query: 118 KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGH 174 + + L+KEL+ + ++++ L + LC++ L T + ++ + G Sbjct: 307 EVLRASLQKELTMGKGQASAMELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGF 363 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLL 228 V + L++ + ++ L + L +V+ LGRR + ++L + LL Sbjct: 364 GVSIYLIQVIF------GAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILL 411 >gi|24497478 solute carrier family 22 member 6 isoform c [Homo sapiens] Length = 506 Score = 68.9 bits (167), Expect = 8e-12 Identities = 56/234 (23%), Positives = 103/234 (44%), Gaps = 15/234 (6%) Query: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60 ++ R G LAGI L L +E P R + + +V GQFL+ G+A Sbjct: 187 IYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH 246 Query: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DI 117 W+ LQ L+ PF +Y F ES RW ++ + + R + + N EG + Sbjct: 247 WRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSM 306 Query: 118 KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGH 174 + + L+KEL+ + ++++ L + LC++ L T + ++ + G Sbjct: 307 EVLRASLQKELTMGKGQASAMELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGF 363 Query: 175 EVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLL 228 V + L++ + ++ L + L +V+ LGRR + ++L + LL Sbjct: 364 GVSIYLIQVIF------GAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILL 411 >gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens] Length = 332 Score = 65.9 bits (159), Expect = 6e-11 Identities = 70/315 (22%), Positives = 133/315 (42%), Gaps = 39/315 (12%) Query: 47 GQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFT 106 G L +A RDW +LQ ++ PF L LY ES RWL+ T + + + + Sbjct: 23 GHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVA 82 Query: 107 QKNRMNPEGDIKGVI-PEL-------EKELSRRPKKV-CIVKVVGTRNLWKNIVVLCVNS 157 +N +G ++ + PE+ E + + P + ++++ G R C+++ Sbjct: 83 A---INGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLR------FRTCIST 133 Query: 158 LTGYGIHHCFARSMMGHEVKVPLL-ENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLL 216 L + F + G + + L N + + + + + +++ LGRR Sbjct: 134 LCWFA----FGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRP--- 186 Query: 217 LFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVF 276 T ASLL GL L H + A +++G+ A + Sbjct: 187 -----TLAASLLLAGLCILANTLVPHEMGALRS--------ALAVLGLGGVGAAFTCITI 233 Query: 277 FCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILL 336 + +E+ PTV+R +GL +A G + P++ L G +L +++ ++ + LL Sbjct: 234 YSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALL 293 Query: 337 LPESRDQNLPENISN 351 LPE++ LP+ I + Sbjct: 294 LPETQSLPLPDTIQD 308 >gi|23510410 solute carrier family 22 member 1 isoform b [Homo sapiens] Length = 506 Score = 60.1 bits (144), Expect = 4e-09 Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 9/225 (4%) Query: 6 RFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQ 65 R +G G + Y L E G R + ++ G + GLA W+ LQ Sbjct: 206 RLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQ 265 Query: 66 ALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELE 125 + P L LLY+ PES RWL++ ++ A +++ H QKN P D+K + LE Sbjct: 266 LAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLK--MLSLE 323 Query: 126 KELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFY 185 ++++ + + T L K +L T ++ M N Y Sbjct: 324 EDVTEK-LSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATS------GNLY 376 Query: 186 ADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 230 D+ +A + + + + +GR + + +L A L+ + Sbjct: 377 LDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMI 421 >gi|166197673 solute carrier family 22, member 15 [Homo sapiens] Length = 547 Score = 59.3 bits (142), Expect = 6e-09 Identities = 88/379 (23%), Positives = 151/379 (39%), Gaps = 40/379 (10%) Query: 2 FSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDW 61 F+ RF G G+ L + L E + + G L R W Sbjct: 165 FAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSW 224 Query: 62 QVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVI 121 + L L+ ++ L PES RWL + + A+ + ++NR +K Sbjct: 225 RTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRK-----LKCTF 279 Query: 122 PELEKELSRRPKKV-CIVKVVGTRNLWKNIVVLC----VNSLTGYGIHHCFARSMMGHEV 176 L +R ++ + + R L + ++L V SL YG+ + +G + Sbjct: 280 -SLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGL--TLSAGDLGGSI 336 Query: 177 KVPLLENFYADYYTTASIALVSCLAMCVVV---RFLGRRGGLLLFMILTALASLLQLGLL 233 YA+ + I + S +C+ + ++ GR+ L F+ L LA L+ + L Sbjct: 337 --------YANLALSGLIEIPS-YPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFL- 386 Query: 234 NLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGL 293 + D+G+ V S + S++G A ++ + +E+ PTVIR GLG Sbjct: 387 ------PEKKDTGVFAVVN---SHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGT 437 Query: 294 VLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353 + G + AP I + L I+F L + LLLPE+ + L E S+ + Sbjct: 438 CSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQ 497 Query: 354 HYTRQPLLPHKKGEQPLLL 372 Y+ + L GE+ L L Sbjct: 498 VYSYRRL-----GEEALSL 511 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.328 0.142 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,945,368 Number of Sequences: 37866 Number of extensions: 627476 Number of successful extensions: 1837 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 1726 Number of HSP's gapped (non-prelim): 71 length of query: 405 length of database: 18,247,518 effective HSP length: 105 effective length of query: 300 effective length of database: 14,271,588 effective search space: 4281476400 effective search space used: 4281476400 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.