BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo sapiens] (449 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo... 940 0.0 gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo ... 940 0.0 gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ... 218 1e-56 gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s... 218 1e-56 gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 203 2e-52 gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 199 6e-51 gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 199 6e-51 gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 199 6e-51 gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 198 9e-51 gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ... 162 4e-40 gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 52 1e-06 gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 47 4e-05 gi|13376840 WD repeat domain 61 [Homo sapiens] 47 4e-05 gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 45 1e-04 gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 45 1e-04 gi|8922301 WD repeat domain 70 [Homo sapiens] 45 1e-04 gi|45594312 TNF receptor-associated factor 7 [Homo sapiens] 43 5e-04 gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 43 5e-04 gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 42 0.001 gi|18874090 WD repeat domain 48 [Homo sapiens] 40 0.006 gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 40 0.006 gi|157266266 WD repeat domain 86 [Homo sapiens] 40 0.006 gi|21071067 TBP-associated factor 5 [Homo sapiens] 39 0.007 gi|26665869 WD repeat domain 51B [Homo sapiens] 39 0.007 gi|21281677 WD repeat domain 36 [Homo sapiens] 39 0.010 gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 39 0.013 gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 39 0.013 gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 39 0.013 gi|38569484 kinesin family member 21A [Homo sapiens] 38 0.016 gi|41281564 WD repeat domain 37 [Homo sapiens] 37 0.028 >gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo sapiens] Length = 572 Score = 940 bits (2429), Expect = 0.0 Identities = 449/449 (100%), Positives = 449/449 (100%) Query: 1 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 60 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA Sbjct: 124 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 183 Query: 61 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 120 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF Sbjct: 184 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 243 Query: 121 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 180 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT Sbjct: 244 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 303 Query: 181 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 240 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD Sbjct: 304 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 363 Query: 241 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 300 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG Sbjct: 364 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 423 Query: 301 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 360 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ Sbjct: 424 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 483 Query: 361 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 420 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS Sbjct: 484 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 543 Query: 421 PVTCCDVSSNNRLVVTGSGEHASVYQITY 449 PVTCCDVSSNNRLVVTGSGEHASVYQITY Sbjct: 544 PVTCCDVSSNNRLVVTGSGEHASVYQITY 572 >gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo sapiens] Length = 449 Score = 940 bits (2429), Expect = 0.0 Identities = 449/449 (100%), Positives = 449/449 (100%) Query: 1 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 60 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA Sbjct: 1 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 60 Query: 61 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 120 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF Sbjct: 61 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 120 Query: 121 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 180 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT Sbjct: 121 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 180 Query: 181 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 240 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD Sbjct: 181 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 240 Query: 241 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 300 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG Sbjct: 241 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 300 Query: 301 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 360 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ Sbjct: 301 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 360 Query: 361 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 420 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS Sbjct: 361 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 420 Query: 421 PVTCCDVSSNNRLVVTGSGEHASVYQITY 449 PVTCCDVSSNNRLVVTGSGEHASVYQITY Sbjct: 421 PVTCCDVSSNNRLVVTGSGEHASVYQITY 449 >gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo sapiens] Length = 621 Score = 218 bits (554), Expect = 1e-56 Identities = 114/314 (36%), Positives = 182/314 (57%), Gaps = 10/314 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ LAHGE+V A IS T+HV+T G+ +KVW + GQ Sbjct: 315 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 368 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 + P + L ++R+C L + RSL+ GG +++S+WDLAAP+ +K +L + Sbjct: 369 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 427 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 316 C AL + DA + F+ + G + +WDL++Q++VR +G+ DG I + Y +WTGG Sbjct: 428 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 487 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +RCWD R + ++ F SQI SL H P +DW+ +GM + + +++ + Sbjct: 488 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 547 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S NN+ +VT Sbjct: 548 HESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVT 607 Query: 437 GSGE-HASVYQITY 449 GSG+ A+VY++ Y Sbjct: 608 GSGDKKATVYEVVY 621 >gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo sapiens] Length = 743 Score = 218 bits (554), Expect = 1e-56 Identities = 114/314 (36%), Positives = 182/314 (57%), Gaps = 10/314 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ LAHGE+V A IS T+HV+T G+ +KVW + GQ Sbjct: 437 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 490 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 + P + L ++R+C L + RSL+ GG +++S+WDLAAP+ +K +L + Sbjct: 491 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 549 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 316 C AL + DA + F+ + G + +WDL++Q++VR +G+ DG I + Y +WTGG Sbjct: 550 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 609 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +RCWD R + ++ F SQI SL H P +DW+ +GM + + +++ + Sbjct: 610 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 669 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S NN+ +VT Sbjct: 670 HESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVT 729 Query: 437 GSGE-HASVYQITY 449 GSG+ A+VY++ Y Sbjct: 730 GSGDKKATVYEVVY 743 >gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] Length = 773 Score = 203 bits (517), Expect = 2e-52 Identities = 108/315 (34%), Positives = 180/315 (57%), Gaps = 10/315 (3%) Query: 138 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 197 PDAL G +P ++ L HGE+V A IS+ TRHV+T G+ +KVW ++ Sbjct: 466 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 519 Query: 198 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 257 ++ P S L ++R+C L + R+L+ GG +++S+WDLAAP+ +K +L + Sbjct: 520 NKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 578 Query: 258 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 315 C AL + D+ + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG Sbjct: 579 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 638 Query: 316 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 375 D +R WD R + ++ F SQI SL + P +W+ +GM N + + ++ + Sbjct: 639 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLH 698 Query: 376 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 435 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S +++ +V Sbjct: 699 LHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 758 Query: 436 TGSGE-HASVYQITY 449 TGSG+ A+VY++ Y Sbjct: 759 TGSGDKKATVYEVIY 773 >gi|157384986 transducin-like enhancer protein 3 isoform b [Homo sapiens] Length = 769 Score = 199 bits (505), Expect = 6e-51 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ L+HGE+V A IS+ TRHV+T G+ +K+W ++ ++ Sbjct: 463 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 518 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 P S L ++R+C L + R+L+ GG +++++WDLA+P+ +K +L + Sbjct: 519 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 575 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 316 C AL + DA + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG Sbjct: 576 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 635 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ + Sbjct: 636 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 695 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S++++ +VT Sbjct: 696 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 755 Query: 437 GSGE-HASVYQITY 449 GSG+ A+VY++ Y Sbjct: 756 GSGDKKATVYEVIY 769 >gi|157384984 transducin-like enhancer protein 3 isoform c [Homo sapiens] Length = 760 Score = 199 bits (505), Expect = 6e-51 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ L+HGE+V A IS+ TRHV+T G+ +K+W ++ ++ Sbjct: 454 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 509 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 P S L ++R+C L + R+L+ GG +++++WDLA+P+ +K +L + Sbjct: 510 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 566 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 316 C AL + DA + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG Sbjct: 567 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 626 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ + Sbjct: 627 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 686 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S++++ +VT Sbjct: 687 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 746 Query: 437 GSGE-HASVYQITY 449 GSG+ A+VY++ Y Sbjct: 747 GSGDKKATVYEVIY 760 >gi|157384982 transducin-like enhancer protein 3 isoform a [Homo sapiens] Length = 772 Score = 199 bits (505), Expect = 6e-51 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ L+HGE+V A IS+ TRHV+T G+ +K+W ++ ++ Sbjct: 466 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 521 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 P S L ++R+C L + R+L+ GG +++++WDLA+P+ +K +L + Sbjct: 522 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 578 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 316 C AL + DA + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG Sbjct: 579 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 638 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ + Sbjct: 639 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 698 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S++++ +VT Sbjct: 699 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 758 Query: 437 GSGE-HASVYQITY 449 GSG+ A+VY++ Y Sbjct: 759 GSGDKKATVYEVIY 772 >gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] Length = 770 Score = 198 bits (503), Expect = 9e-51 Identities = 106/315 (33%), Positives = 179/315 (56%), Gaps = 10/315 (3%) Query: 138 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 197 PDAL G +P ++ L HGE+V A IS+ TRHV+T G+ +KVW ++ Sbjct: 463 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 516 Query: 198 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 257 ++ P S L ++R+C L + +L+ GG +++S+WDLAAP+ +K +L + Sbjct: 517 NKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 575 Query: 258 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 315 C AL + D+ + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG Sbjct: 576 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 635 Query: 316 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 375 D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ + Sbjct: 636 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLH 695 Query: 376 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 435 +S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S +++ +V Sbjct: 696 LHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 755 Query: 436 TGSGE-HASVYQITY 449 TGSG+ A+VY++ Y Sbjct: 756 TGSGDKKATVYEVIY 770 >gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo sapiens] Length = 706 Score = 162 bits (411), Expect = 4e-40 Identities = 88/251 (35%), Positives = 143/251 (56%), Gaps = 9/251 (3%) Query: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198 DAL G +P ++ LAHGE+V A IS T+HV+T G+ +KVW + GQ Sbjct: 451 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 504 Query: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258 + P + L ++R+C L + RSL+ GG +++S+WDLAAP+ +K +L + Sbjct: 505 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 563 Query: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 316 C AL + DA + F+ + G + +WDL++Q++VR +G+ DG I + Y +WTGG Sbjct: 564 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 623 Query: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376 D +RCWD R + ++ F SQI SL H P +DW+ +GM + + +++ + Sbjct: 624 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 683 Query: 377 KDSVILSVKFS 387 +S +LS+KF+ Sbjct: 684 HESCVLSLKFA 694 >gi|83779014 katanin p80 subunit B 1 [Homo sapiens] Length = 655 Score = 51.6 bits (122), Expect = 1e-06 Identities = 49/223 (21%), Positives = 85/223 (38%), Gaps = 46/223 (20%) Query: 221 SNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 280 ++ R L TGG + V++W + P+ + L +++ N L A SG + Sbjct: 31 ASGRLLATGGDD-CRVNLWSINKPNCIMS--LTGHTSPVESVRLNTPEELIVAGSQSGSI 87 Query: 281 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGPDACLRCWDQRTIMKPLEYQFKS 338 R+WDL ++R L G+ + S+ Y + +G D ++ WD R Y+ S Sbjct: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHS 147 Query: 339 QIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGM 398 Q + ++FSP G+W AS Sbjct: 148 Q----------------------------------------AVRCLRFSPDGKWLASAAD 167 Query: 399 DDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGSGE 440 D + ++ + AG + E P PV + N L+ +GS + Sbjct: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210 Score = 30.8 bits (68), Expect = 2.6 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 10/103 (9%) Query: 217 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 276 CL S L + +V +WDL A + + P ++ + + L + + Sbjct: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKM--MSEFPGHTGPVNVVEFHPNEYLLASGSS 209 Query: 277 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDAC 319 +R WDL VV ++G P V+S++ PD C Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSVLF--------NPDGC 244 >gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo sapiens] Length = 504 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 5/132 (3%) Query: 280 VRIWDLRDQSVVRDLKGYPDGVKSIVV--KGYNIWTGGPDACLRCWDQRTI--MKPLEYQ 335 ++IWDL++++ V + G+ + SI GY + T D+ ++ WD R + K L+ Sbjct: 374 IKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLD 433 Query: 336 FKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWAS 395 ++ SL ++ LG + Q ++ H + + V F ++ AS Sbjct: 434 NNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFT-EHSGLTTGVAFGHHAKFIAS 492 Query: 396 VGMDDFLGVYSM 407 GMD L YS+ Sbjct: 493 TGMDRSLKFYSL 504 >gi|13376840 WD repeat domain 61 [Homo sapiens] Length = 305 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 26/188 (13%) Query: 279 VVRIWDLRDQ--SVVRDLKGYPDGVKSIVVKGYN--IWTGGPDACLRCWDQRTIMKPLEY 334 +V++W RD+ + L+G+ GV S+ + + DA +R WD Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLEN------- 95 Query: 335 QFKSQIMSLSHSPQEDWVLLGMANGQQWLQST-----------SGSQRHMVGQKDSVILS 383 QI S+ P + W L + Q T SG + + + + ILS Sbjct: 96 --GKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILS 153 Query: 384 VKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGSGE-H 441 + +SP G++ AS +D + ++ + G + + P+ S +++L+VT S + + Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213 Query: 442 ASVYQITY 449 +Y + + Sbjct: 214 IKIYDVQH 221 >gi|62234438 Notchless gene homolog isoform b [Homo sapiens] Length = 193 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 19/136 (13%) Query: 196 AEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD------LAAPSLHVK 249 AED+ P + + A + L S +SR + + ++ S+ +WD LA+ HV Sbjct: 67 AEDKKPLTRMTGHQ--ALINQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVA 123 Query: 250 EQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSI--VVK 307 A + D+ L + + +++WD++ Q + DL G+ D V ++ Sbjct: 124 AVYQIAW--------SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPD 175 Query: 308 GYNIWTGGPDACLRCW 323 G + +GG D CLR W Sbjct: 176 GQRVASGGKDKCLRIW 191 >gi|62234461 Notchless gene homolog isoform a [Homo sapiens] Length = 485 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 19/136 (13%) Query: 196 AEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD------LAAPSLHVK 249 AED+ P + + A + L S +SR + + ++ S+ +WD LA+ HV Sbjct: 359 AEDKKPLTRMTGHQ--ALINQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVA 415 Query: 250 EQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSI--VVK 307 A + D+ L + + +++WD++ Q + DL G+ D V ++ Sbjct: 416 AVYQIAW--------SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPD 467 Query: 308 GYNIWTGGPDACLRCW 323 G + +GG D CLR W Sbjct: 468 GQRVASGGKDKCLRIW 483 Score = 33.5 bits (75), Expect = 0.40 Identities = 37/169 (21%), Positives = 67/169 (39%), Gaps = 16/169 (9%) Query: 162 HGELVLATAISSFTRHVFT-CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLS 220 H E V++ A S +++ + G ++ W L+ + H + ++ + S Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETP-------HFTCKGHRHWVLSISWS 165 Query: 221 SNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLP-----CAGLNCQALDANLDANLAFASF 275 + R L +G N + +WD + V L GL+ + L AN + +S Sbjct: 166 PDGRKLASGCKN-GQILLWD-PSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 223 Query: 276 TSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN-IWTGGPDACLRCW 323 G VRIWD R L G+ V + G +++ D ++ W Sbjct: 224 KDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVW 272 >gi|8922301 WD repeat domain 70 [Homo sapiens] Length = 654 Score = 45.1 bits (105), Expect = 1e-04 Identities = 69/278 (24%), Positives = 108/278 (38%), Gaps = 42/278 (15%) Query: 199 RFPESHLPIQTPGAFLRTCL-LSSNSRSLLTGGYNLASVSVWDLAAPSLHVK---EQLPC 254 + P+SH G + L L + L+TGGY+ V WD A K PC Sbjct: 169 KIPDSHEITLKHGTKTVSALGLDPSGARLVTGGYDY-DVKFWDFAGMDASFKAFRSLQPC 227 Query: 255 AGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNI--- 311 ++L + ++ S ++ D V+ +KG V KG+ Sbjct: 228 ECHQIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLH 287 Query: 312 ---W---------TGGPDACLRCWD------QRTIMKPLEYQFKSQI-MSLSHSPQEDWV 352 W T DA +R W+ Q+++ KP Q K I + ++S + + Sbjct: 288 TGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLI 347 Query: 353 LLGMANG--QQWLQSTSG------SQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGV 404 NG Q W ++ + Q H G S V FS G AS G DD L + Sbjct: 348 AAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSC---VTFSYDGNVLASRGGDDSLKL 404 Query: 405 YSMPAGTKVF----EVPEMSPVTCCDVSSNNRLVVTGS 438 + + K +P M P+T C S +++L+VTG+ Sbjct: 405 WDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGT 442 >gi|45594312 TNF receptor-associated factor 7 [Homo sapiens] Length = 670 Score = 43.1 bits (100), Expect = 5e-04 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 5/108 (4%) Query: 217 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 276 C L S+ L +G +L ++ VWD+ L +K++L GLN + A + A S + Sbjct: 483 CTLVSSHNVLFSG--SLKAIKVWDIVGTELKLKKEL--TGLN-HWVRALVAAQSYLYSGS 537 Query: 277 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWD 324 ++IWD+R + L+ V SI V ++I G + + WD Sbjct: 538 YQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWD 585 Score = 31.2 bits (69), Expect = 2.0 Identities = 13/63 (20%), Positives = 32/63 (50%), Gaps = 1/63 (1%) Query: 269 NLAFASFTSGVVRIWDL-RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 +L F+ + +++WD + L+G+ V ++ ++G +++G D + WD + Sbjct: 409 DLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQN 468 Query: 328 IMK 330 + K Sbjct: 469 LQK 471 >gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] Length = 357 Score = 43.1 bits (100), Expect = 5e-04 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 6/151 (3%) Query: 262 LDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN---IWTGGPDA 318 L N D ++ F++ T V +WD V+ LKG+ V S + TG D Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174 Query: 319 CLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG--QQWLQSTSGSQRHMVGQ 376 ++ WD R +Q Q+++++ + D ++ G + + W + M G Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGH 234 Query: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSM 407 DSV + S G + S MD+ + V+ + Sbjct: 235 ADSV-TGLSLSSEGSYLLSNAMDNTVRVWDV 264 >gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] Length = 589 Score = 41.6 bits (96), Expect = 0.001 Identities = 55/265 (20%), Positives = 107/265 (40%), Gaps = 38/265 (14%) Query: 214 LRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQ---LPCAGLNCQALDANLDAN- 269 L T +S +S+ LL G++ + + +W L + L + + L C L+ D + Sbjct: 271 LNTAEISPDSK-LLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDD 329 Query: 270 ------------------LAFASFTSGV--------VRIWDLRDQSVVRDLKGYPDGVKS 303 F + +SG+ +R WDL + +G+ V Sbjct: 330 NAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWD 389 Query: 304 IVVKGYNIW--TGGPDACLRCWD-QRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG- 359 + + Y+++ +G D R W RT + + + + P +++ G + Sbjct: 390 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKT 449 Query: 360 -QQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEV-P 417 + W S R G + V LS+ FSP G++ AS G D L ++ + +GT E+ Sbjct: 450 VRLWSAQQGNSVRLFTGHRGPV-LSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRG 508 Query: 418 EMSPVTCCDVSSNNRLVVTGSGEHA 442 +T S ++ L+ + S +++ Sbjct: 509 HTDNITSLTFSPDSGLIASASMDNS 533 Score = 29.3 bits (64), Expect = 7.6 Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 220 SSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGV 279 S N + L + G + + +WDLA+ +L+ ++L N +L + D+ L ++ Sbjct: 477 SPNGKYLASAGED-QRLKLWDLASGTLY--KELRGHTDNITSLTFSPDSGLIASASMDNS 533 Query: 280 VRIWDLRD 287 VR+WD+R+ Sbjct: 534 VRVWDIRN 541 >gi|18874090 WD repeat domain 48 [Homo sapiens] Length = 677 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/164 (23%), Positives = 65/164 (39%), Gaps = 17/164 (10%) Query: 216 TCLLSSNSRSLLTGGYN-LASVSVWDLAAPSLHVKEQLPCAGL--------NCQALDANL 266 T LS N S+ + N L ++ V L V + CA L N +AL N Sbjct: 161 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR 220 Query: 267 DANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKG--YNIWTGGPDACLRCWD 324 D + + G +R+W L Q + + + +GV ++ V ++++GG D + C D Sbjct: 221 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD 280 Query: 325 QRT------IMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQW 362 R I + K ++ + P WV + +W Sbjct: 281 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKW 324 >gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapiens] Length = 522 Score = 39.7 bits (91), Expect = 0.006 Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 12/167 (7%) Query: 281 RIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRT--IMKPLEYQF 336 R+WDL Q + +G+ GV I G TGG DA R WD RT + LE Sbjct: 348 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407 Query: 337 KSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQR---HMVGQKDSVILSVKFSPF-GQW 392 K +I ++ SP + G +G + QR + + +++ VKF P G + Sbjct: 408 K-EIYGINFSPNGYHIATG--SGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNF 464 Query: 393 WASVGMDDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGS 438 + D+ +++ P + + + V D+SS+ +L+ T S Sbjct: 465 LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 511 Score = 34.7 bits (78), Expect = 0.18 Identities = 39/150 (26%), Positives = 61/150 (40%), Gaps = 13/150 (8%) Query: 180 TCGRRG-IKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSV 238 +C G +K+WSL E I+ + + + R L T Y+ S + Sbjct: 298 SCAADGSVKLWSLDSD-------EPVADIEGHTVRVARVMWHPSGRFLGTTCYD-RSWRL 349 Query: 239 WDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYP 298 WDL A + ++ G+ A + D +LA R+WDLR + L+G+ Sbjct: 350 WDLEAQEEILHQEGHSMGVYDIAF--HQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407 Query: 299 DGVKSI--VVKGYNIWTGGPDACLRCWDQR 326 + I GY+I TG D + WD R Sbjct: 408 KEIYGINFSPNGYHIATGSGDNTCKVWDLR 437 >gi|157266266 WD repeat domain 86 [Homo sapiens] Length = 376 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 2/107 (1%) Query: 217 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 276 C + + LL G + VW +A+ H + + C LD + AF T Sbjct: 156 CAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDT--PGHTAFTGST 213 Query: 277 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCW 323 +R WD+ +R + + V + + +++G D ++CW Sbjct: 214 DATIRAWDILSGEQLRVFREHRGSVICLELVNRLVYSGSADRTVKCW 260 Score = 35.8 bits (81), Expect = 0.081 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 17/94 (18%) Query: 233 LASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVR 292 LA + WDL PS E+ GL T G ++W + + Sbjct: 143 LAYSAPWDL--PSTPCAEEAAAGGL-------------LVTGSTDGTAKVWQVASGCCHQ 187 Query: 293 DLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWD 324 L+G+ V +V+ G+ +TG DA +R WD Sbjct: 188 TLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWD 221 >gi|21071067 TBP-associated factor 5 [Homo sapiens] Length = 800 Score = 39.3 bits (90), Expect = 0.007 Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%) Query: 261 ALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACL 320 A+D D++L F VR+W + + +R +K D S++ K D Sbjct: 475 AVDVTDDSSLIAGGFADSTVRVWSVTPKK-LRSVKQASD--LSLIDK------ESDDVLE 525 Query: 321 RCWDQRTIMK-PLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQK-- 377 R D++T + + Y + S SP +++L +G L S + +VG K Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ-TFTCLVGYKGH 584 Query: 378 DSVILSVKFSPFGQWWASVGMDDFLGVYSMP--AGTKVFEVPEMSPVTCCDVSSNNRLVV 435 + + +FSP+G ++ S G D +++ ++F ++ V C N+ V Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF-AGHLADVNCTRFHPNSNYVA 643 Query: 436 TGSGE 440 TGS + Sbjct: 644 TGSAD 648 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 11/180 (6%) Query: 267 DANLAFASFTSGVVRIWDLRDQSVVRDLKG--YPDGVKSIVVKGYNIWTGGPDACLRCWD 324 D N +S G VR+W L+ + + KG YP GY +GG D R W Sbjct: 554 DRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW- 612 Query: 325 QRTIMKPLEYQFKSQIMSLS---HSPQEDWVLLGMANG--QQWLQSTSGSQRHMVGQKDS 379 +PL F + ++ P ++V G A+ + W R G K Sbjct: 613 ATDHYQPLRI-FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHK-G 670 Query: 380 VILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTC-CDVSSNNRLVVTGS 438 I S+ FSP G++ A+ D + ++ + G V E+ + C S + ++ +GS Sbjct: 671 PIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGS 730 Score = 32.3 bits (72), Expect = 0.90 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 276 TSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRTIMKPLE 333 T G V +WD+ +V +LKG+ D V S+ G + +G D +R WD + LE Sbjct: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLE 748 >gi|26665869 WD repeat domain 51B [Homo sapiens] Length = 478 Score = 39.3 bits (90), Expect = 0.007 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 23/170 (13%) Query: 162 HGELVLATAISSFTRHVFTCGR-RGIKVWSLTGQVAEDRFPES-----HLPIQTPGAFLR 215 H V S R + +C + IK+W T + + F +S + G Sbjct: 143 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG---- 198 Query: 216 TCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASF 275 TC+ S+ S +V VWD+ L Q+ G+NC + + N + Sbjct: 199 TCIASAGSDQ---------TVKVWDVRVNKLLQHYQVHSGGVNC--ISFHPSGNYLITAS 247 Query: 276 TSGVVRIWDLRDQSVVRDLKGYPDGVKSI-VVKGYNIW-TGGPDACLRCW 323 + G ++I DL + ++ L+G+ V ++ KG ++ +GG D + W Sbjct: 248 SDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297 Score = 30.4 bits (67), Expect = 3.4 Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%) Query: 287 DQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRTIMKPLEYQ-FKSQIMSL 343 D + R KG+ + S+ + G + T D L W+ + + Y K + S+ Sbjct: 7 DPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSV 66 Query: 344 SHSPQEDWVLLGMANGQQ----WLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMD 399 SP + LL A+ + W+ G + + SV FS GQ+ A+ D Sbjct: 67 QFSPHGN--LLASASRDRTVRLWIPDKRGKFSEFKAHT-APVRSVDFSADGQFLATASED 123 Query: 400 DFLGVYSMPAGTKVFEVPEMSP-VTCCDVSSNNRLVVTGS 438 + V+SM ++ + + V C S + RL+V+ S Sbjct: 124 KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163 >gi|21281677 WD repeat domain 36 [Homo sapiens] Length = 951 Score = 38.9 bits (89), Expect = 0.010 Identities = 47/207 (22%), Positives = 82/207 (39%), Gaps = 30/207 (14%) Query: 257 LNCQALDANLDANLAFASFTSGVVRIWDLRDQ----SVVRDLKGYPDGVKSIVVKGYN-- 310 + A+D N A +SG V +++++ S +D + + V+ + V G N Sbjct: 495 ITATAVDITSCGNFAVIGLSSGTVDVYNMQSGIHRGSFGKD-QAHKGSVRGVAVDGLNQL 553 Query: 311 IWTGGPDACLRCWDQRTIMKPLEYQFKSQIM----SLSHSPQ-----EDWVLLGMANGQQ 361 T G + L+ W+ FK++I+ SLS SP D +LG+A Sbjct: 554 TVTTGSEGLLKFWN-----------FKNKILIHSVSLSSSPNIMLLHRDSGILGLALDDF 602 Query: 362 WLQSTSGSQRHMVGQ---KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPE 418 + R +V + I + FSP G+W S MD + + +P+G + Sbjct: 603 SISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPSGCLIDCFLL 662 Query: 419 MSPVTCCDVSSNNRLVVTGSGEHASVY 445 S +S + T +H +Y Sbjct: 663 DSAPLNVSMSPTGDFLATSHVDHLGIY 689 >gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo sapiens] Length = 589 Score = 38.5 bits (88), Expect = 0.013 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 227 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 285 + G A++ VWD+ LHV A + C D + A+ +V++WD Sbjct: 356 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 410 Query: 286 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 ++ + L+G+ + V S+ G ++ +G D +R WD T Sbjct: 411 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 452 Score = 32.7 bits (73), Expect = 0.69 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%) Query: 222 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 280 + R +++G Y+ V VWD + LH + G + D + + Sbjct: 392 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 445 Query: 281 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 R+WD+ + + L G+ + +K + +G D+ ++ WD +T Sbjct: 446 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 492 Score = 29.6 bits (65), Expect = 5.8 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 186 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 244 +KVW PE+ + T G R L + +++G + S+ VWD+ Sbjct: 405 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 453 Query: 245 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 303 + +H G L N+ + V+IWD++ ++ L+G + Sbjct: 454 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 508 Query: 304 IVVKGYN---IWTGGPDACLRCWDQRT 327 + +N + T D ++ WD +T Sbjct: 509 VTCLQFNKNFVITSSDDGTVKLWDLKT 535 >gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo sapiens] Length = 707 Score = 38.5 bits (88), Expect = 0.013 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 227 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 285 + G A++ VWD+ LHV A + C D + A+ +V++WD Sbjct: 474 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 528 Query: 286 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 ++ + L+G+ + V S+ G ++ +G D +R WD T Sbjct: 529 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 570 Score = 32.7 bits (73), Expect = 0.69 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%) Query: 222 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 280 + R +++G Y+ V VWD + LH + G + D + + Sbjct: 510 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 563 Query: 281 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 R+WD+ + + L G+ + +K + +G D+ ++ WD +T Sbjct: 564 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 610 Score = 29.6 bits (65), Expect = 5.8 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 186 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 244 +KVW PE+ + T G R L + +++G + S+ VWD+ Sbjct: 523 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 571 Query: 245 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 303 + +H G L N+ + V+IWD++ ++ L+G + Sbjct: 572 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 626 Query: 304 IVVKGYN---IWTGGPDACLRCWDQRT 327 + +N + T D ++ WD +T Sbjct: 627 VTCLQFNKNFVITSSDDGTVKLWDLKT 653 >gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo sapiens] Length = 627 Score = 38.5 bits (88), Expect = 0.013 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 227 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 285 + G A++ VWD+ LHV A + C D + A+ +V++WD Sbjct: 394 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 448 Query: 286 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 ++ + L+G+ + V S+ G ++ +G D +R WD T Sbjct: 449 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 490 Score = 32.7 bits (73), Expect = 0.69 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%) Query: 222 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 280 + R +++G Y+ V VWD + LH + G + D + + Sbjct: 430 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 483 Query: 281 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 327 R+WD+ + + L G+ + +K + +G D+ ++ WD +T Sbjct: 484 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 530 Score = 29.6 bits (65), Expect = 5.8 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 186 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 244 +KVW PE+ + T G R L + +++G + S+ VWD+ Sbjct: 443 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 491 Query: 245 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 303 + +H G L N+ + V+IWD++ ++ L+G + Sbjct: 492 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 546 Query: 304 IVVKGYN---IWTGGPDACLRCWDQRT 327 + +N + T D ++ WD +T Sbjct: 547 VTCLQFNKNFVITSSDDGTVKLWDLKT 573 >gi|38569484 kinesin family member 21A [Homo sapiens] Length = 1661 Score = 38.1 bits (87), Expect = 0.016 Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 236 VSVWDLAAPSLHVKEQLPCAGLNCQ-ALDANLDANLAFASFTSGVVRIWDLRDQSVVRDL 294 + WDL L +Q+P A + AL D + + G++++W++ V ++ Sbjct: 1552 IKKWDLTQKDL--LQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEM 1609 Query: 295 KGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRTI 328 KG+ + +I V +I+T D +R W R + Sbjct: 1610 KGHDSPINAICVNSTHIFTAADDRTVRIWKARNL 1643 Score = 33.1 bits (74), Expect = 0.53 Identities = 46/228 (20%), Positives = 90/228 (39%), Gaps = 23/228 (10%) Query: 155 EKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFL 214 E M + H V++ ++T VFT IKVW + R S + A Sbjct: 1366 EIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACS 1425 Query: 215 ----RTCLLSSNSRSLL------TGGYNLAS----VSVWDLAAPSLHVKEQLPCAGLNCQ 260 RT + S + TG + A+ V +WDL K + C Sbjct: 1426 ASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCL 1485 Query: 261 ALDA-NLDANLAFASFTSGVVRIWDLRDQSV--VRDLKGYP----DGVKSIVVKGYNIWT 313 +D + +L ++++D+ + ++ V + DG++++ ++G N+++ Sbjct: 1486 TVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFS 1545 Query: 314 GGPDACLRCWD--QRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG 359 G D ++ WD Q+ +++ + K + +L P +L G G Sbjct: 1546 GSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGG 1593 >gi|41281564 WD repeat domain 37 [Homo sapiens] Length = 494 Score = 37.4 bits (85), Expect = 0.028 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 270 LAFASFTSGVVRIWDLRDQSV--VRDLKGYPDGVKSIV-VKGYNIWTGGPDACLRCWDQR 326 L S R+WD RD S+ V +G+ D V S V G N+ +G D ++ WD + Sbjct: 337 LVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLK 396 Query: 327 TIMKPL 332 + P+ Sbjct: 397 NMRSPI 402 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,539,906 Number of Sequences: 37866 Number of extensions: 1073756 Number of successful extensions: 5708 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 177 Number of HSP's that attempted gapping in prelim test: 5250 Number of HSP's gapped (non-prelim): 594 length of query: 449 length of database: 18,247,518 effective HSP length: 106 effective length of query: 343 effective length of database: 14,233,722 effective search space: 4882166646 effective search space used: 4882166646 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.