Guide to the Human Genome
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Name: TLE4 Sequence: fasta or formatted (773aa) NCBI GI: 34915994
Description:

transducin-like enhancer protein 4

Referenced in:

Notch Pathway
WD Repeat Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         64          11
 C cysteine            2.2         17           2
 D aspartate           5.3         41           2
 E glutamate           4.5         35           2
 F phenylalanine       2.2         17           1
 G glycine             6.9         53           2
 H histidine           4.3         33           3
 I isoleucine          4.9         38           2
 K lysine              5.6         43           2
 L leucine             7.5         58           2
 M methionine          1.7         13           1
 N asparagine          3.6         28           1
 P proline             8.5         66           2
 Q glutamine           4.8         37           3
 R arginine            4.1         32           1
 S serine             11.0         85           4
 T threonine           5.0         39           2
 V valine              5.8         45           2
 W tryptophan          1.0          8           1
 Y tyrosine            2.7         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transducin-like enhancer protein 4 
TLE1                  0.858   transducin-like enhancer protein 1 
TLE3                  0.812   transducin-like enhancer protein 3 isoform b 
TLE3                  0.808   transducin-like enhancer protein 3 isoform a 
TLE3                  0.796   transducin-like enhancer protein 3 isoform c 
TLE2                  0.624   transducin-like enhancer protein 2 isoform 1 
TLE2                  0.540   transducin-like enhancer protein 2 isoform 2 
TLE2                  0.490   transducin-like enhancer protein 2 isoform 3 
AES                   0.153   amino-terminal enhancer of split isoform b 
AES                   0.149   amino-terminal enhancer of split isoform c 
AES                   0.147   amino-terminal enhancer of split isoform a 
TLE6                  0.114   transducin-like enhancer of split 6 isoform 1 [Homo...
TLE6                  0.114   transducin-like enhancer of split 6 isoform 2 
WDR51A                0.043   WD repeat domain 51A isoform 3 
WDR51A                0.043   WD repeat domain 51A isoform 2 
WDR51A                0.043   WD repeat domain 51A isoform 1 
WDR51B                0.040   WD repeat domain 51B 
SNRNP40               0.037   WD repeat domain 57 (U5 snRNP specific) 
GNB5                  0.037   guanine nucleotide-binding protein, beta-5 subunit is...
GNB5                  0.037   guanine nucleotide-binding protein, beta-5 subunit i...
PRPF4                 0.031   PRP4 pre-mRNA processing factor 4 homolog 
WSB1                  0.030   WD repeat and SOCS box-containing 1 isoform 1 
GNB2L1                0.029   guanine nucleotide binding protein (G protein), beta ...
GNB4                  0.029   guanine nucleotide-binding protein, beta-4 subunit [...
GNB3                  0.029   guanine nucleotide-binding protein, beta-3 subunit [H...
KATNB1                0.029   katanin p80 subunit B 1 
TAF5L                 0.028   PCAF associated factor 65 beta isoform a 
WSB2                  0.028   WD SOCS-box protein 2 
TAF5                  0.028   TBP-associated factor 5 
WSB1                  0.028   WD repeat and SOCS box-containing 1 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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