Guide to the Human Genome
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Name: TLE1 Sequence: fasta or formatted (770aa) NCBI GI: 21541824
Description:

transducin-like enhancer protein 1

Referenced in:

Notch Pathway
WD Repeat Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         64           7
 C cysteine            2.1         16           2
 D aspartate           5.8         45           2
 E glutamate           4.0         31           2
 F phenylalanine       2.3         18           1
 G glycine             7.4         57           2
 H histidine           4.2         32           2
 I isoleucine          4.3         33           2
 K lysine              5.5         42           2
 L leucine             8.2         63           2
 M methionine          2.1         16           1
 N asparagine          3.6         28           1
 P proline             8.7         67           3
 Q glutamine           4.8         37           3
 R arginine            3.9         30           2
 S serine             10.3         79           3
 T threonine           5.2         40           1
 V valine              5.7         44           2
 W tryptophan          1.0          8           1
 Y tyrosine            2.6         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transducin-like enhancer protein 1 
TLE4                  0.859   transducin-like enhancer protein 4 
TLE3                  0.785   transducin-like enhancer protein 3 isoform a 
TLE3                  0.784   transducin-like enhancer protein 3 isoform b 
TLE3                  0.774   transducin-like enhancer protein 3 isoform c 
TLE2                  0.617   transducin-like enhancer protein 2 isoform 1 
TLE2                  0.537   transducin-like enhancer protein 2 isoform 2 
TLE2                  0.503   transducin-like enhancer protein 2 isoform 3 
AES                   0.139   amino-terminal enhancer of split isoform b 
AES                   0.137   amino-terminal enhancer of split isoform c 
AES                   0.134   amino-terminal enhancer of split isoform a 
TLE6                  0.111   transducin-like enhancer of split 6 isoform 1 [Homo...
TLE6                  0.111   transducin-like enhancer of split 6 isoform 2 
WDR51A                0.041   WD repeat domain 51A isoform 3 
WDR51A                0.041   WD repeat domain 51A isoform 2 
WDR51A                0.041   WD repeat domain 51A isoform 1 
GNB5                  0.040   guanine nucleotide-binding protein, beta-5 subunit is...
GNB5                  0.040   guanine nucleotide-binding protein, beta-5 subunit i...
WDR51B                0.039   WD repeat domain 51B 
SNRNP40               0.038   WD repeat domain 57 (U5 snRNP specific) 
PRPF4                 0.031   PRP4 pre-mRNA processing factor 4 homolog 
GNB3                  0.029   guanine nucleotide-binding protein, beta-3 subunit [H...
GNB4                  0.028   guanine nucleotide-binding protein, beta-4 subunit [...
WSB1                  0.028   WD repeat and SOCS box-containing 1 isoform 1 
WSB2                  0.028   WD SOCS-box protein 2 
GNB2L1                0.028   guanine nucleotide binding protein (G protein), beta ...
KATNB1                0.027   katanin p80 subunit B 1 
TAF5L                 0.027   PCAF associated factor 65 beta isoform a 
WDR61                 0.026   WD repeat domain 61 
WDR5                  0.026   WD repeat domain 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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