Guide to the Human Genome
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Name: TLE2 Sequence: fasta or formatted (706aa) NCBI GI: 221219048
Description:

transducin-like enhancer protein 2 isoform 2

Referenced in:

Notch Pathway
WD Repeat Proteins

Other entries for this name:
alt prot [743aa] transducin-like enhancer protein 2 isoform 1
alt prot [621aa] transducin-like enhancer protein 2 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         60           3
 C cysteine            2.8         20           2
 D aspartate           4.7         33           1
 E glutamate           5.4         38           3
 F phenylalanine       2.1         15           1
 G glycine             7.2         51           4
 H histidine           3.1         22           2
 I isoleucine          3.4         24           2
 K lysine              3.7         26           1
 L leucine             9.9         70           2
 M methionine          1.3          9           1
 N asparagine          1.7         12           1
 P proline             8.4         59           2
 Q glutamine           6.4         45           3
 R arginine            4.2         30           2
 S serine             12.9         91           3
 T threonine           4.2         30           2
 V valine              7.1         50           2
 W tryptophan          0.8          6           1
 Y tyrosine            2.1         15           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transducin-like enhancer protein 2 isoform 2 
TLE2                  0.956   transducin-like enhancer protein 2 isoform 1 
TLE2                  0.736   transducin-like enhancer protein 2 isoform 3 
TLE4                  0.604   transducin-like enhancer protein 4 
TLE1                  0.599   transducin-like enhancer protein 1 
TLE3                  0.586   transducin-like enhancer protein 3 isoform b 
TLE3                  0.586   transducin-like enhancer protein 3 isoform a 
TLE3                  0.582   transducin-like enhancer protein 3 isoform c 
AES                   0.132   amino-terminal enhancer of split isoform c 
AES                   0.130   amino-terminal enhancer of split isoform a 
AES                   0.130   amino-terminal enhancer of split isoform b 
TLE6                  0.098   transducin-like enhancer of split 6 isoform 1 [Homo...
TLE6                  0.098   transducin-like enhancer of split 6 isoform 2 
WDR51A                0.036   WD repeat domain 51A isoform 3 
WDR51A                0.036   WD repeat domain 51A isoform 2 
WDR51A                0.036   WD repeat domain 51A isoform 1 
GNB2L1                0.033   guanine nucleotide binding protein (G protein), beta ...
WDR51B                0.032   WD repeat domain 51B 
KATNB1                0.031   katanin p80 subunit B 1 
WSB2                  0.029   WD SOCS-box protein 2 
GNB5                  0.029   guanine nucleotide-binding protein, beta-5 subunit is...
GNB5                  0.029   guanine nucleotide-binding protein, beta-5 subunit i...
WSB1                  0.029   WD repeat and SOCS box-containing 1 isoform 1 
WDR38                 0.028   WD repeat domain 38 
SNRNP40               0.027   WD repeat domain 57 (U5 snRNP specific) 
TAF5                  0.027   TBP-associated factor 5 
SMU1                  0.026   smu-1 suppressor of mec-8 and unc-52 homolog 
NSMAF                 0.025   neutral sphingomyelinase (N-SMase) activation associ...
NSMAF                 0.025   neutral sphingomyelinase (N-SMase) activation assoc...
NLE1                  0.025   Notchless gene homolog isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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