Guide to the Human Genome
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Name: TLE6 Sequence: fasta or formatted (572aa) NCBI GI: 221136834
Description:

transducin-like enhancer of split 6 isoform 1

Referenced in:

Notch Pathway
WD Repeat Proteins

Other entries for this name:
alt prot [449aa] transducin-like enhancer of split 6 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         35           2
 C cysteine            2.3         13           2
 D aspartate           5.8         33           2
 E glutamate           5.6         32           2
 F phenylalanine       3.7         21           1
 G glycine             7.0         40           2
 H histidine           2.3         13           2
 I isoleucine          3.5         20           1
 K lysine              4.4         25           1
 L leucine             8.2         47           2
 M methionine          1.7         10           1
 N asparagine          2.6         15           2
 P proline             8.0         46           2
 Q glutamine           6.8         39           2
 R arginine            5.2         30           2
 S serine             11.0         63           3
 T threonine           4.7         27           1
 V valine              6.3         36           2
 W tryptophan          3.0         17           2
 Y tyrosine            1.7         10           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transducin-like enhancer of split 6 isoform 1 [Homo... 
TLE6                  0.787   transducin-like enhancer of split 6 isoform 2 
TLE2                  0.166   transducin-like enhancer protein 2 isoform 3 
TLE2                  0.166   transducin-like enhancer protein 2 isoform 1 
TLE4                  0.153   transducin-like enhancer protein 4 
TLE3                  0.150   transducin-like enhancer protein 3 isoform b 
TLE3                  0.150   transducin-like enhancer protein 3 isoform c 
TLE3                  0.150   transducin-like enhancer protein 3 isoform a 
TLE1                  0.149   transducin-like enhancer protein 1 
TLE2                  0.118   transducin-like enhancer protein 2 isoform 2 
KATNB1                0.023   katanin p80 subunit B 1 
PRPF19                0.019   PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom...
WDR61                 0.019   WD repeat domain 61 
NLE1                  0.017   Notchless gene homolog isoform b 
NLE1                  0.017   Notchless gene homolog isoform a 
WDR70                 0.017   WD repeat domain 70 
TRAF7                 0.015   TNF receptor-associated factor 7 
SNRNP40               0.015   WD repeat domain 57 (U5 snRNP specific) 
TAF5L                 0.015   PCAF associated factor 65 beta isoform a 
WDR48                 0.013   WD repeat domain 48 
PRPF4                 0.013   PRP4 pre-mRNA processing factor 4 homolog 
WDR86                 0.013   WD repeat domain 86 
TAF5                  0.012   TBP-associated factor 5 
WDR51B                0.012   WD repeat domain 51B 
WDR36                 0.012   WD repeat domain 36 
FBXW7                 0.012   F-box and WD repeat domain containing 7 isoform 3 [H...
FBXW7                 0.012   F-box and WD repeat domain containing 7 isoform 1 [H...
FBXW7                 0.012   F-box and WD repeat domain containing 7 isoform 2 [H...
KIF21A                0.011   kinesin family member 21A 
WDR37                 0.010   WD repeat domain 37 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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