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Search of human proteins with 4826690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo
sapiens]
(1220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 2429 0.0
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 762 0.0
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 761 0.0
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 669 0.0
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 608 e-173
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 558 e-158
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 520 e-147
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 395 e-109
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 385 e-106
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 379 e-105
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 307 5e-83
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 270 5e-72
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 270 5e-72
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 256 1e-67
gi|166851804 tudor domain containing 9 [Homo sapiens] 223 9e-58
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 216 1e-55
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 214 5e-55
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 199 1e-50
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 196 1e-49
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 175 3e-43
gi|38505213 YTH domain containing 2 [Homo sapiens] 160 7e-39
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 87 1e-16
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 86 2e-16
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 79 3e-14
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 78 4e-14
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 78 4e-14
gi|41393554 LUC7-like isoform b [Homo sapiens] 73 1e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 71 7e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 71 7e-12
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 2429 bits (6295), Expect = 0.0
Identities = 1220/1220 (100%), Positives = 1220/1220 (100%)
Query: 1 MAVAVAMAGALIGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKN 60
MAVAVAMAGALIGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKN
Sbjct: 1 MAVAVAMAGALIGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKN 60
Query: 61 TTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFP 120
TTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFP
Sbjct: 61 TTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFP 120
Query: 121 VLCQPDNPSVRTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSR 180
VLCQPDNPSVRTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSR
Sbjct: 121 VLCQPDNPSVRTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSR 180
Query: 181 DRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK 240
DRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK
Sbjct: 181 DRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK 240
Query: 241 YGERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISEL 300
YGERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISEL
Sbjct: 241 YGERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISEL 300
Query: 301 RREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNE 360
RREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNE
Sbjct: 301 RREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNE 360
Query: 361 ETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFD 420
ETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFD
Sbjct: 361 ETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFD 420
Query: 421 EETGILPKVDDEEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQS 480
EETGILPKVDDEEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQS
Sbjct: 421 EETGILPKVDDEEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQS 480
Query: 481 ALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKK 540
ALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKK
Sbjct: 481 ALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKK 540
Query: 541 HAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQ 600
HAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQ
Sbjct: 541 HAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQ 600
Query: 601 YLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKY 660
YLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKY
Sbjct: 601 YLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKY 660
Query: 661 MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL 720
MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL
Sbjct: 661 MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL 720
Query: 721 DAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFL 780
DAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFL
Sbjct: 721 DAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFL 780
Query: 781 TGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATN 840
TGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATN
Sbjct: 781 TGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATN 840
Query: 841 IAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCY 900
IAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCY
Sbjct: 841 IAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCY 900
Query: 901 RLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQ 960
RLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQ
Sbjct: 901 RLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQ 960
Query: 961 LYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYR 1020
LYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYR
Sbjct: 961 LYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYR 1020
Query: 1021 PKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRK 1080
PKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRK
Sbjct: 1021 PKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRK 1080
Query: 1081 QMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSA 1140
QMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSA
Sbjct: 1081 QMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSA 1140
Query: 1141 LFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEP 1200
LFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEP
Sbjct: 1141 LFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEP 1200
Query: 1201 LYNRYEEPNAWRISRAFRRR 1220
LYNRYEEPNAWRISRAFRRR
Sbjct: 1201 LYNRYEEPNAWRISRAFRRR 1220
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 762 bits (1967), Expect = 0.0
Identities = 368/650 (56%), Positives = 492/650 (75%), Gaps = 12/650 (1%)
Query: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGC 615
SI R SLP++ +E+L+ A+ ++Q+LI+ GETGSGKTTQI QYL E GYT++G KI C
Sbjct: 391 SIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC 450
Query: 616 TQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPD 675
TQPRRVAAMSVA RV+ E G LG EVGY+IRFEDCTS TV++YMTDGMLLRE L +PD
Sbjct: 451 TQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPD 510
Query: 676 LTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIF 735
L Y+++M+DEAHERT+HTD+LFGL+K + R ++K++V SAT+D +FS +F +AP+F
Sbjct: 511 LASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVF 570
Query: 736 TIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYE 795
IPGR +PV+I YTK PE DYL+A +++V+QIH+T+PPGDILVFLTGQEEI+ ACE+L +
Sbjct: 571 RIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQD 630
Query: 796 RMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVV 855
+ LG + EL++LP+Y+ LPS+MQ RIF P PPG+RKVV+ATNIAETS TI+GI YV+
Sbjct: 631 PCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVL 690
Query: 856 DPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTT 915
DPGF KQK YN +TG++ L VTP S+A A QRAGRAGR GKC+RLYT AY+ E+ T
Sbjct: 691 DPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEET 750
Query: 916 NVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTR 975
VPEIQRT+L + VL LK++GI+DL+ FDF+D PP ETL+ +EQLY LGAL+ G LT
Sbjct: 751 TVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNHLGELTT 810
Query: 976 LGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAK 1034
GR+MAE P++PML KM++ S CSEE+LT+ +MLSV N +FYRPKDK AD +
Sbjct: 811 SGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVN 870
Query: 1035 FHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVV 1094
F GDHL LL VY W + +S+ WC ENF+Q RS+RRA+D+R+Q+ G+++R ++ +
Sbjct: 871 FFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVREQLEGLLERVEVGLS 930
Query: 1095 SCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHEL 1154
SC +RV+KAI +G+F + A+ + GYRT+ QQ V+IHP+S+LF +QP W++YHEL
Sbjct: 931 SCQGDYIRVRKAITAGYFYHTARL-TRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL 989
Query: 1155 VLTTKEYMREVTTIDPRWLVEFAPAFFKVSD---------PTKLSKQKKQ 1195
VLTTKE+MR+V I+ WL+E AP ++K + P K+ K +++
Sbjct: 990 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREE 1039
Score = 38.5 bits (88), Expect = 0.039
Identities = 52/254 (20%), Positives = 104/254 (40%), Gaps = 30/254 (11%)
Query: 37 ELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGA-EFTDSLISNLLRLIQTMRPP 95
EL + LG++++ +A+F+I A++ T+ + F L + + LRL +
Sbjct: 14 ELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRK 73
Query: 96 A---KPSTSKDPVVKPKTEKEKLKELFPVLCQPDNPSV-----------------RTMLD 135
A KP+ + + + EK + L + +V R +
Sbjct: 74 AVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKRE 133
Query: 136 EDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRD-RNRDRDRDRERNR 194
E++ + A + K+ + +++ E D ++ +R R +D RD +R R R
Sbjct: 134 EEEEEEASEKGKK-----KTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQR 188
Query: 195 DRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY-GERNLDRWRDKH 253
D+D R RS ++ + ++K R ++ P +K R +Y +R ++ D
Sbjct: 189 DKDRTRNVLERSDKKAYEEAQKRLKMAEEDR-KAMIPELRKKSRREYLAKREREKLEDLE 247
Query: 254 VDRPPPEEPTIGDI 267
+ EE GD+
Sbjct: 248 AEL-ADEEFLFGDV 260
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 761 bits (1966), Expect = 0.0
Identities = 457/1111 (41%), Positives = 651/1111 (58%), Gaps = 123/1111 (11%)
Query: 159 QEKQRDAEHRDR----TKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSR---SRSR 211
+ +QR+ E R+ + K+++ ++++RDRD DR+R+RD + RH SRS R
Sbjct: 131 RSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSER 190
Query: 212 TRERNKVKSR---------------------YRSRSRSQ----SPPKDRKDRDK---YGE 243
+ RN+ +S Y S RSQ SP +D ++
Sbjct: 191 SSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLST 250
Query: 244 RNLDRW-RDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLE-GLRKRWEGLVHISELR 301
R+ DR R K+ D P P+ YN G +L G +R EG IS
Sbjct: 251 RDRDRSVRGKYSDDTPLPTPSYK--YNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDT 308
Query: 302 REGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNEE 361
E R D QR + +D+ E NP + ++E+
Sbjct: 309 EEERQQWEDD-----QR-----------QADRDWYMMDEGYDEFHNP------LAYSSED 346
Query: 362 TSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDE 421
R R HL + S +R+++ D E+WE +M+ + V+ + E +
Sbjct: 347 YVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTSGVVHRLEVDE--- 395
Query: 422 ETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQ 479
D EED ++ L+ PPFL G + P+ VK+ L+ A
Sbjct: 396 --------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKG 447
Query: 480 SALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRG--IGMMPNDIPE 537
S ++ RE K+ ++ +KHW ++A G +G+ + P+
Sbjct: 448 SQTVRKHREQKERKKAQ---------HKHW----------ELAGTKLGDIMGVKKEEEPD 488
Query: 538 ----------------WKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDN 581
+ H ++AS + SILEQR+ LPI+ ++++L+ + DN
Sbjct: 489 KAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDN 548
Query: 582 QILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQE 641
I+IV+GETGSGKTTQ+TQYL E GYT G IGCTQPRRVAAMSVAKRVSEE G LG+E
Sbjct: 549 SIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEE 608
Query: 642 VGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLL 701
VGY IRFEDCTS T+IKYMTDG+LLRE L + DL Y+ I++DEAHER+++TDVLFGLL
Sbjct: 609 VGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLL 668
Query: 702 KKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASL 761
++ V +R D+KLIVTSAT+DA KF+ +F PIF IPGRT+PV+IL++K P+ DY++A++
Sbjct: 669 REVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAV 728
Query: 762 ITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQ 821
+Q+HL+ PGDIL+F+ GQE+I+ + + E ++ L + P L +LP+YS LPS++Q
Sbjct: 729 KQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQ 787
Query: 822 TRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQ 881
+IF AP G RK ++ATNIAETSLT+DGI +V+D G+ K KV+N + G+D L + PISQ
Sbjct: 788 AKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQ 847
Query: 882 AQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLL 941
A A QR+GRAGRTGPG+C+RLYT+ AY++E+LTT VPEIQRTNLA+ VL LK++G+ DLL
Sbjct: 848 ANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLL 907
Query: 942 SFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGC 1001
F FMD PP + ++ +M QL+ LGALD+ G LT GR M EFPL+P L KMLI+S +GC
Sbjct: 908 QFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGC 967
Query: 1002 SEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPW 1061
S E+L IVSMLSV +FYRPK ++ +DQ + KF E DHLT L VY WKNN +S W
Sbjct: 968 SSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIW 1027
Query: 1062 CYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQ 1121
C ++FI A+++R+ +++R Q+ IM + ++ + SCG V+K IC+ +F AAK
Sbjct: 1028 CNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGI 1087
Query: 1122 EGYRTLIDQQVVYIHPSSALFNR--QPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPA 1179
Y + ++HP+S+LF P+++VYHELV+TTKEYM+ VT +D WL E P
Sbjct: 1088 GEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPM 1147
Query: 1180 FFKVSDPTKLSKQKKQQRLEPLYNRYEEPNA 1210
F+ V K S+Q+ ++R + + EE A
Sbjct: 1148 FYSVKQAGK-SRQENRRRAKEEASAMEEEMA 1177
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens]
Length = 795
Score = 669 bits (1726), Expect = 0.0
Identities = 343/655 (52%), Positives = 464/655 (70%), Gaps = 15/655 (2%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGK---IG 614
IL++R LP+++ K++ + +Q +++GETGSGKTTQI Q+ E + G +
Sbjct: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
Query: 615 CTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDP 674
CTQPRRVAAMSVA+RV++E LGQEVGY+IRFEDC+S +T++KYMTDGMLLRE + DP
Sbjct: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDP 249
Query: 675 DLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPI 734
L +Y +I+LDEAHERT+ TD+L G+LK+ V++R D+K+IV SATLDA KF YF P+
Sbjct: 250 LLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPL 309
Query: 735 FTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP-GDILVFLTGQEEIDTACEIL 793
TIPGRT+PVEI YT EPE DYL+A++ TV+QIH+ E GD+L+FLTGQEEID AC+ +
Sbjct: 310 LTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI 369
Query: 794 YERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGS------RKVVIATNIAETSLT 847
+ LGP+V ++ I+P+YS LP + Q RIF+P PP RKVV++TNIAETSLT
Sbjct: 370 KREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLT 429
Query: 848 IDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERA 907
IDG+ +V+DPGF KQKVYN + ++ L+VT IS+A A+QRAGRAGRT PGKC+RLYTE+A
Sbjct: 430 IDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKA 489
Query: 908 YRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
Y+ EM PEI R+NL S VL LK +GI+DL+ FDFMD P ETL+ A+E L L AL
Sbjct: 490 YKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 549
Query: 968 DDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQAL 1027
+D+G LT LG MAEFPL+P L KM+I S CS E+L+I +MLSV F RP + +
Sbjct: 550 NDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKA 609
Query: 1028 ADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMD 1087
AD+ K +F +GDHLTLL VY+++K N S WCY+NFI RSL A ++R+Q+ IMD
Sbjct: 610 ADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMD 669
Query: 1088 RHKLDVVSCGKST----VRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFN 1143
R L S ++ + ++KA+ +G+F A + Y T+ D QVV +HPS+ L +
Sbjct: 670 RFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-D 728
Query: 1144 RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRL 1198
+PEWV+Y+E VLTTK Y+R T I P WLV+ AP ++ +S+ + +++ R+
Sbjct: 729 HKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRI 783
Score = 42.7 bits (99), Expect = 0.002
Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query: 169 DRTKKKKRSRSRDRNRDRDRDRE-RNRDRDHKRRHRSRSRSRSRTRER 215
D KKR+ + ++RDRDRDRE R++DRD +R R R R + +E+
Sbjct: 12 DYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
Score = 37.7 bits (86), Expect = 0.067
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERN 216
E + R T K R R RDR DR +DR+R RDR + R R + + + N
Sbjct: 11 EDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKELRASTN 66
Score = 36.2 bits (82), Expect = 0.20
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 7/45 (15%)
Query: 158 GQEKQRDAEHRDRTKKKKRSRSRDRNRDR-DRDRERNRDRDHKRR 201
G+++ RD + D RS+ RDR RDR DR+RER ++++ + R
Sbjct: 24 GKDRDRDRDRED------RSKDRDRERDRGDREREREKEKEKELR 62
Score = 32.7 bits (73), Expect = 2.2
Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 186 RDRDRERNRDRDHKRRHRSRSR-SRSRTRERNKVK 219
+DRDR+R+R+ K R R R R R R RE+ K K
Sbjct: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 608 bits (1568), Expect = e-173
Identities = 321/714 (44%), Positives = 471/714 (65%), Gaps = 32/714 (4%)
Query: 502 PMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQ 561
P+G K W P EG ++ + + N G Y +SI +Q
Sbjct: 4 PVGPVKFW---RPGTEGPGVSISEERQSLAENS----------GTTVVYNPYAALSIEQQ 50
Query: 562 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKI-GCTQPRR 620
R+ LP++KL+ ++ + + Q ++++GETG GK+TQI QYLAEAG+T+ G++ G TQPRR
Sbjct: 51 RQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRR 110
Query: 621 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSP-ETVIKYMTDGMLLRECLIDPDLTQY 679
VAA++VA RV+EE G LG EVGY IRF+DCT T IK++TDGML+RE ++DP LT+Y
Sbjct: 111 VAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKY 170
Query: 680 AIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYE-------- 731
++IMLDEAHERT++TD+ GLLKK +KR D++LIV SATLDA KF +F +
Sbjct: 171 SVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPAR 230
Query: 732 --APIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTA 789
I T+ GRT+PV+I Y + P DY+ +++ TV++IH TE GD+L FLTGQEE++T
Sbjct: 231 DTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETV 290
Query: 790 CEILYERMKSLGPDVPE--LIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLT 847
+L E+ ++L + L +LP+Y+ LPS Q ++F+ RKV++ATN+AETS+T
Sbjct: 291 VSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSIT 350
Query: 848 IDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERA 907
I GI YV+D GFVK + YN +T I+ LVV P+SQA A QRAGR GR+ GKCYRLYTE A
Sbjct: 351 ISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEA 410
Query: 908 YRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
+ D++ + VPE+QR+NLA +L LKA+GI+++L F FM PP ++++ A+E LY LG L
Sbjct: 411 F-DKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGL 469
Query: 968 DDEGLLTR-LGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQA 1026
D + LT LG R+AEFPL PM KML+ S + GCS+E+L+I +M+ +QN+F P ++++
Sbjct: 470 DKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKS 529
Query: 1027 LADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIM 1086
A + KF EGDHLT+L +Y ++ + + WC E+F+ + L RA +R+Q+ ++
Sbjct: 530 HAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLL 589
Query: 1087 DRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALF-NRQ 1145
+ ++ S V + I SGFF NAA+ YRT+ D ++IHP+S L+ +
Sbjct: 590 VKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKP 649
Query: 1146 PEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLE 1199
P WV+Y+E++ T+K YMR+VT I+ WL+E AP F++ T LS + K+ +++
Sbjct: 650 PRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQ--QGTHLSLKAKRAKVQ 701
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 558 bits (1438), Expect = e-158
Identities = 300/633 (47%), Positives = 415/633 (65%), Gaps = 14/633 (2%)
Query: 561 QRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRR 620
QR SLPI++ + QL+ + + ++IGETGSGKTTQI QYL E G + +G I TQPRR
Sbjct: 70 QRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRR 129
Query: 621 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYA 680
VAA+S+A RVS+E LG+ VGYT+RF+D TS +T IK++TDGMLLRE + D L +Y+
Sbjct: 130 VAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYS 189
Query: 681 IIMLDEAHERTIHTDVLFGLLKKTVQKRQDM-----KLIVTSATLDAVKFSQYFYEAPIF 735
++LDEAHERTIHTDVLFG++K ++R+++ K+IV SAT+D FSQYF AP+
Sbjct: 190 CVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVL 249
Query: 736 TIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPG-DILVFLTGQEEIDTACEILY 794
+ GR +P+++ YTK+P+ DYL A+L++V QIH P DILVFLTGQEEI+ +
Sbjct: 250 YLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCR 309
Query: 795 ERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYV 854
+ K L P +++LP+Y++LP Q R+F AP G RKV+I+TNIAETS+TI GI YV
Sbjct: 310 DIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYV 369
Query: 855 VDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYR--DEM 912
VD G VK K YN +G++ L V +S+ QA QR GRAGR G CYRLYTE + D+M
Sbjct: 370 VDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKM 429
Query: 913 LTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL---DD 969
VPEIQR NLAS +L L AM + ++L+FDFM P + + A+ QL LGAL DD
Sbjct: 430 ---TVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGALEHKDD 486
Query: 970 EGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALAD 1029
+ LT +GR+MA FPLEP K ++MS C+EE+LTIVS+LSV +V + P ++
Sbjct: 487 QLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLHNPPSRREEVQ 546
Query: 1030 QKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRH 1089
+ KF +EGDH+TLL +Y ++KN + WC ENF+ ++++ ++R Q+ I +
Sbjct: 547 GVRKKFISSEGDHMTLLNIYRTFKNLGGNKDWCKENFVNSKNMTLVAEVRAQLRDICLKM 606
Query: 1090 KLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWV 1149
+ + S V++ + F + A+ P Y T Q V IHPSS LF+ +P V
Sbjct: 607 SMPIASSRGDVESVRRCLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLFHCKPACV 666
Query: 1150 VYHELVLTTKEYMREVTTIDPRWLVEFAPAFFK 1182
VY EL+ T K YMR++ ID +WL E AP +F+
Sbjct: 667 VYTELLYTNKCYMRDLCVIDAQWLYEAAPEYFR 699
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 520 bits (1338), Expect = e-147
Identities = 286/666 (42%), Positives = 420/666 (63%), Gaps = 33/666 (4%)
Query: 564 SLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAA 623
+ PI K +++++QAV DN LIV G TGSGKTTQ+ +YL EAG++ G IG TQPR+VAA
Sbjct: 52 TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
Query: 624 MSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIM 683
+SVA+RV+EE C LG +VGY +RF+DC+S ET IKYMTDG LL+ L DP+LT++++I+
Sbjct: 112 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
Query: 684 LDEAHERTIHTDVLFGLLKKTVQ-----KRQDMKLIVTSATLDAVKFSQYFYEAPIFTIP 738
LDEAHERT+ TD+LFGLLKK Q +++ +K++V SAT++ K S +F PIF IP
Sbjct: 172 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
Query: 739 GRTYPVEILYTK------EPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEI 792
GR YPV + T Y+ A + M IHL E GDILVFLTGQ EI+ +CE+
Sbjct: 232 GRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 291
Query: 793 LYERMKSLGPD-------VPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETS 845
L++ +S+ D + L+ILP Y ++ ++ Q RIF P PPG RK VI+TNI+ TS
Sbjct: 292 LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 351
Query: 846 LTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTE 905
LTIDGI YVVD GFVKQ +N + G+D L V PIS+++A QR+GRAGRT GKC+R+Y++
Sbjct: 352 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 411
Query: 906 RAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLG 965
+ M +PEI+RT+L S VL+LK + I+D++ F ++D P ++ A++QLY
Sbjct: 412 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD 471
Query: 966 ALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDK- 1024
A+D G +TRLG M EFPL P L +I + L C + +L I +MLSV+NVF RP D
Sbjct: 472 AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE 531
Query: 1025 -QALADQKKAKFHQTEG---DHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRK 1080
Q A+Q+ + G D TL ++ K++ WC +++I R L A +
Sbjct: 532 YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA 591
Query: 1081 QMLGIMDRHKLD-----VVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQ-QVVY 1134
Q+ ++ + K G +++ +C+G+F+N A++ + T+ + V+
Sbjct: 592 QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVH 651
Query: 1135 IHPSSALFNRQP--EWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAF--FKVSDPTKLS 1190
IHPSSAL ++ EW+++HE+++TTK Y R V I W+ + P F D + ++
Sbjct: 652 IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA 711
Query: 1191 KQKKQQ 1196
+++ ++
Sbjct: 712 RREVRE 717
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 395 bits (1015), Expect = e-109
Identities = 204/398 (51%), Positives = 279/398 (70%), Gaps = 18/398 (4%)
Query: 564 SLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAA 623
+ PI K +++++QAV DN LIV G TGSGKTTQ+ +YL EAG++ G IG TQPR+VAA
Sbjct: 52 TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
Query: 624 MSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIM 683
+SVA+RV+EE C LG +VGY +RF+DC+S ET IKYMTDG LL+ L DP+LT++++I+
Sbjct: 112 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
Query: 684 LDEAHERTIHTDVLFGLLKKTVQ-----KRQDMKLIVTSATLDAVKFSQYFYEAPIFTIP 738
LDEAHERT+ TD+LFGLLKK Q +++ +K++V SAT++ K S +F PIF IP
Sbjct: 172 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
Query: 739 GRTYPVEILYTK------EPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEI 792
GR YPV + T Y+ A + M IHL E GDILVFLTGQ EI+ +CE+
Sbjct: 232 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 291
Query: 793 LYERMKSLGPD-------VPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETS 845
L++ +S+ D + L+ILP Y ++ ++ Q RIF P PPG RK VI+TNI+ TS
Sbjct: 292 LFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 351
Query: 846 LTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTE 905
LTIDGI YVVD GFVKQ +N + G+D L V PIS+++A QR+GRAGRT GKC+R+Y++
Sbjct: 352 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 411
Query: 906 RAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSF 943
+ M +PEI+RT+L S VL+LK + I+D++ +
Sbjct: 412 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 385 bits (988), Expect = e-106
Identities = 227/669 (33%), Positives = 375/669 (56%), Gaps = 31/669 (4%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE---AGYTSRGKIG 614
+L++RE LPI+K K ++ + NQI+IV G+ GK+ Q+ Q+ AE + + G +
Sbjct: 55 LLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVI 114
Query: 615 CTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDP 674
CTQ + + +A RV++E +G EVGY I FE+C + ET+++Y TD ML RE + +P
Sbjct: 115 CTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNP 174
Query: 675 DLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPI 734
L Y +I+LD+ HER+I TDVL GLLK + R ++KLI+ S+ K + Y+ P+
Sbjct: 175 FLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPV 234
Query: 735 FTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILY 794
+ + +PVE++Y E + D ++ L + +IH + GDI+VFL +++I+ CE +Y
Sbjct: 235 IEVKNK-HPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVY 293
Query: 795 ERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGS-------RKVVIATNIAETSLT 847
+ +L PD+ EL+++P+Y P E + +F P R+VV+ T+ E +
Sbjct: 294 QG-SNLNPDLGELVVVPLY---PKE-KCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIW 348
Query: 848 IDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERA 907
+ + +V+D G ++KVYN + + LV+ PISQ+QA+ R G + GK + LYTE
Sbjct: 349 SNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEF 408
Query: 908 YRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
+M E+Q NL S VL +K + I L DFM+ P E+L+ A+E L L AL
Sbjct: 409 ASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAAL 468
Query: 968 DDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVF-YRPKDKQA 1026
D++G L+ G M+EFPL+P L K ++ S C +E+LTI +M++ N F + P +
Sbjct: 469 DNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEE 528
Query: 1027 LADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSN-------PWCYENFIQARSLRRAQDIR 1079
A F EGDH TL+++Y ++++ ++ WC + F+ +LR A IR
Sbjct: 529 AALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIR 588
Query: 1080 KQMLGIMDRHKL----DVVSCGKSTVRVQKAICSGFFRNAAKK-DPQEGYRTLIDQQVVY 1134
++L I+ R +L ++T+ ++KA+ SG+F A+ D Y L +QV
Sbjct: 589 AELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQ 648
Query: 1135 IHPSS--ALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQ 1192
+HP S ++ + PEWV++H+ ++ Y+R + I P ++ P ++ + P SK
Sbjct: 649 LHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYYFSNLPPSESKD 708
Query: 1193 KKQQRLEPL 1201
QQ ++ L
Sbjct: 709 ILQQVVDHL 717
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens]
Length = 1143
Score = 379 bits (974), Expect = e-105
Identities = 222/581 (38%), Positives = 335/581 (57%), Gaps = 30/581 (5%)
Query: 545 GNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE 604
G K ++G+ ++ +R +LPI + +++Q + ++Q+++V G+TG GK+TQ+ QYL
Sbjct: 144 GQKQAFGRLAKLQ--RERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLA 201
Query: 605 AGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDG 664
AG++ + CTQPRR+A +S+AKRV E G +VGY IRFE S T I ++T G
Sbjct: 202 AGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVG 258
Query: 665 MLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVK 724
+LLR+ +P L QY ++++DE HER +H D L G+L++ + R D+K+I+ SAT++
Sbjct: 259 LLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISL 318
Query: 725 FSQYFYEAPIFTIPGRTYPVEILY---TKEPET---DYLDAS--LITVMQIHLTEPP--- 773
FS YF AP+ +PGR +P+ ++Y EP T + LD L + I PP
Sbjct: 319 FSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEER 378
Query: 774 GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSR 833
GD+LVFL+G EI + E ++ ++LP++SAL Q ++FD APPG R
Sbjct: 379 GDLLVFLSGMAEISA----VLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVR 434
Query: 834 KVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGR 893
K +++TNIAETS+TIDGI +VVD G VK+ Y+ + + +L ISQA A+QR GRAGR
Sbjct: 435 KCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGR 494
Query: 894 TGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMET 953
TGPG C+RLY E Y D VPEI+R L S VL +K+M + D +F F++ PP +
Sbjct: 495 TGPGVCFRLYAESDY-DAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPAS 553
Query: 954 LITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLS 1013
L TA+ L GALD LT +G +A+ P++ ++ KMLI+ E +LTI + LS
Sbjct: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
Query: 1014 VQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSW-----KNNKFSNPWCYENFIQ 1068
VQ+ F R + +GD TL V+N+W + ++ S WC I+
Sbjct: 614 VQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIE 673
Query: 1069 ARSLRRAQDIRKQMLGIMDRHKL----DVVSCGKSTVRVQK 1105
L ++R+Q +++ H L G S R+Q+
Sbjct: 674 EHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQ 714
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 307 bits (786), Expect = 5e-83
Identities = 216/661 (32%), Positives = 340/661 (51%), Gaps = 24/661 (3%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQ--ILIVIGETGSGKTTQITQYLAEAGYT---SRGK 612
+L+QR++LPI+ + ++ + N +++V GE GSGK+TQI Q+ AE +G+
Sbjct: 38 LLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQ 97
Query: 613 IGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLI 672
+ TQP +AA S+A RV++E LG EVGY+I EDCT P T++++ D +LL+E
Sbjct: 98 VTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVAS 157
Query: 673 DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQ--DMKLIVTSATLDAVKFSQYFY 730
+ +++LDEA ER++ +D L GLL+ ++ D++++V + K ++
Sbjct: 158 TRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWG 217
Query: 731 EAPIFTIPGRT--YPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDT 788
PI IP P I + P D ++A+ V+++ E PGD+LVFL +EEI
Sbjct: 218 NPPIVHIPREPGERPSPIYWDTIPP-DRVEAACQAVLELCRKELPGDVLVFLPSEEEISL 276
Query: 789 ACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTI 848
CE L ++SL +LP++ +Q D +RKVV+ +A+ S ++
Sbjct: 277 CCESLSREVESLLLQGLPPRVLPLHPDCGRAVQAVYEDM---DARKVVVTHWLADFSFSL 333
Query: 849 DGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAY 908
I +V+D G + VYN + + V+ PIS+ QA+ R RA PG C LY +
Sbjct: 334 PSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFL 393
Query: 909 RDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALD 968
E P + NL+S VL LK I + F+D P E L+ A+E L L ALD
Sbjct: 394 ELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALD 453
Query: 969 DEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALA 1028
D+G L+ LG ++EFPL P L K L+ S C +EMLT+ +ML+ F RP A
Sbjct: 454 DDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEA 513
Query: 1029 DQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDR 1088
++A H T+GDH +L+ VY ++ + WC + +L +A +R ++L +M R
Sbjct: 514 ALRRALEH-TDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHKLRGELLELMQR 572
Query: 1089 HK--LDVVSCGKSTVR--VQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFN- 1143
+ L + + G R +QKA+ SG+F A+ G L+ + V S +
Sbjct: 573 IELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYRS 632
Query: 1144 -----RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRL 1198
R P WV+YH ++ + V+ I P+ LVE AP +F + P S+ Q
Sbjct: 633 RRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPSESRDLLNQLR 692
Query: 1199 E 1199
E
Sbjct: 693 E 693
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 270 bits (691), Expect = 5e-72
Identities = 204/668 (30%), Positives = 334/668 (50%), Gaps = 66/668 (9%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEA----GYTSRGKI 613
+ ++ LP+ ++ ++ A+ + ++++ G+TG GKTT+I Q L E G +R +
Sbjct: 388 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447
Query: 614 GCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCT-SPETVIKYMTDGMLLRECLI 672
TQPRR++A+SVA+RVS E G L + VG+ +R E S + + T G+LLR+
Sbjct: 448 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507
Query: 673 DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEA 732
+P L + +++DE HER ++TD L LLK + ++L++ SAT D +FS+YF
Sbjct: 508 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567
Query: 733 PIFTIPGRTYPVEILYTKE-------------------PETDYLDASLITVMQIHLTE-- 771
P+ +PG YPV+ Y ++ + LD L+T + +H+
Sbjct: 568 PVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARG 627
Query: 772 PPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPG 831
PG IL FL G +EI + L E +LG + +ILPV+S +P Q IF P G
Sbjct: 628 EPGGILCFLPGWQEIKGVQQRLQE---ALGMHESKYLILPVHSNIPMMDQKAIFQQPPVG 684
Query: 832 SRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRA 891
RK+V+ATNIAETS+TI+ I +VVD G K++ Y+ KT + L +S+A QR GRA
Sbjct: 685 VRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRA 744
Query: 892 GRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFM----D 947
GR G Y L+ R+ ++M+ VPEI RT L + VL K + + + + +F+ D
Sbjct: 745 GRCQSGFAYHLF-PRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVD 802
Query: 948 APPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLT 1007
+P ++ + A+ L +G LD LT LG+R+A +P L K ++++ C +L
Sbjct: 803 SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 862
Query: 1008 IVSMLSVQNVFYRPKDKQALADQKKAKF-HQTEGDHLTLLAVYNS------WKNNKFSNP 1060
+VS L+ ++ F +A D+ KA H + DHL + W++
Sbjct: 863 VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 921
Query: 1061 WCYENFIQARSLRRAQDIRKQ---------MLGIMDRHKLDVVSCGKSTVR---VQKAIC 1108
+ EN + A SLR + KQ ++G L C + + V+ +
Sbjct: 922 YLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLM 981
Query: 1109 SGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTI 1168
+G + N + ++G T + P+S + + ++ H+ + RE T +
Sbjct: 982 AGLYPNLIQ--VRQGKVTRQGK----FKPNSVTYRTKSGNILLHKSTIN-----REATRL 1030
Query: 1169 DPRWLVEF 1176
RWL F
Sbjct: 1031 RSRWLTYF 1038
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 270 bits (691), Expect = 5e-72
Identities = 204/668 (30%), Positives = 334/668 (50%), Gaps = 66/668 (9%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEA----GYTSRGKI 613
+ ++ LP+ ++ ++ A+ + ++++ G+TG GKTT+I Q L E G +R +
Sbjct: 427 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 486
Query: 614 GCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCT-SPETVIKYMTDGMLLRECLI 672
TQPRR++A+SVA+RVS E G L + VG+ +R E S + + T G+LLR+
Sbjct: 487 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 546
Query: 673 DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEA 732
+P L + +++DE HER ++TD L LLK + ++L++ SAT D +FS+YF
Sbjct: 547 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 606
Query: 733 PIFTIPGRTYPVEILYTKE-------------------PETDYLDASLITVMQIHLTE-- 771
P+ +PG YPV+ Y ++ + LD L+T + +H+
Sbjct: 607 PVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARG 666
Query: 772 PPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPG 831
PG IL FL G +EI + L E +LG + +ILPV+S +P Q IF P G
Sbjct: 667 EPGGILCFLPGWQEIKGVQQRLQE---ALGMHESKYLILPVHSNIPMMDQKAIFQQPPVG 723
Query: 832 SRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRA 891
RK+V+ATNIAETS+TI+ I +VVD G K++ Y+ KT + L +S+A QR GRA
Sbjct: 724 VRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRA 783
Query: 892 GRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFM----D 947
GR G Y L+ R+ ++M+ VPEI RT L + VL K + + + + +F+ D
Sbjct: 784 GRCQSGFAYHLF-PRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVD 841
Query: 948 APPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLT 1007
+P ++ + A+ L +G LD LT LG+R+A +P L K ++++ C +L
Sbjct: 842 SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 901
Query: 1008 IVSMLSVQNVFYRPKDKQALADQKKAKF-HQTEGDHLTLLAVYNS------WKNNKFSNP 1060
+VS L+ ++ F +A D+ KA H + DHL + W++
Sbjct: 902 VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 960
Query: 1061 WCYENFIQARSLRRAQDIRKQ---------MLGIMDRHKLDVVSCGKSTVR---VQKAIC 1108
+ EN + A SLR + KQ ++G L C + + V+ +
Sbjct: 961 YLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLM 1020
Query: 1109 SGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTI 1168
+G + N + ++G T + P+S + + ++ H+ + RE T +
Sbjct: 1021 AGLYPNLIQ--VRQGKVTRQGK----FKPNSVTYRTKSGNILLHKSTIN-----REATRL 1069
Query: 1169 DPRWLVEF 1176
RWL F
Sbjct: 1070 RSRWLTYF 1077
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 256 bits (653), Expect = 1e-67
Identities = 179/593 (30%), Positives = 291/593 (49%), Gaps = 71/593 (11%)
Query: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGC- 615
+IL++RE LP+ K + ++++A+ N ++I+ G TG GKTTQ+ Q++ + + C
Sbjct: 380 AILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECN 439
Query: 616 ---TQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTS-PETVIKYMTDGMLLRECL 671
TQPRR++A+SVA+RV+ E G G+ GY++RFE P I + T G+LLR+
Sbjct: 440 IVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRK-- 497
Query: 672 IDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYE 731
++ + + +++DE HER I+TD L +L+ VQ ++++++ SAT+D F +YF+
Sbjct: 498 LEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFN 557
Query: 732 APIFTIPGRTYPVEILYTKE-----------------------PETDYLDASLIT----- 763
PI + GRTYPV+ + ++ E D + +LI
Sbjct: 558 CPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYG 617
Query: 764 -----------------------VMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL 800
+ I PG +LVFL G I T + L E
Sbjct: 618 PETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHL-EMNPHF 676
Query: 801 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV 860
G + ILP++S +P E Q ++FDP P G KV+++TNIAETS+TI+ + YV+D
Sbjct: 677 GSHRYQ--ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQ 734
Query: 861 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI 920
K K++ + + S+ +QR GRAGR PG C+ L RA + + T PE+
Sbjct: 735 KVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHL-CSRARFERLETHMTPEM 793
Query: 921 QRTNLASTVLSLKAMGINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGR 978
RT L LS+K + + + F ++ PP++ +I A L L ALD LT LGR
Sbjct: 794 FRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGR 853
Query: 979 RMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQT 1038
+A+ P+EP KM+IM + + TI + F + + A
Sbjct: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRLGYIHRNFA--GNR 911
Query: 1039 EGDHLTLLAVYNSWKNNKFSNP-----WCYENFIQARSLRRAQDIRKQMLGIM 1086
DH+ LL+V+ +W + + +C + +LR + + Q+ I+
Sbjct: 912 FSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEIL 964
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 223 bits (568), Expect = 9e-58
Identities = 169/591 (28%), Positives = 284/591 (48%), Gaps = 85/591 (14%)
Query: 565 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG---KIGCTQPRRV 621
LPI + KE++V + N ++I+ G TGSGK+TQ+ QY+ + Y R I TQPR++
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDH-YVQRSAYCSIVVTQPRKI 190
Query: 622 AAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAI 681
A S+A+ +S+E LG VGY + E + +T + YMT G+LL++ + L ++
Sbjct: 191 GASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTH 250
Query: 682 IMLDEAHERTIHTDVLFGLLKKTVQKRQD-MKLIVTSATLDAVKFSQYFY--------EA 732
I++DE HERT D L +++K ++ +K+++ SAT+ +F+ YF A
Sbjct: 251 IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310
Query: 733 PIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP------------------- 773
IF + G+ + VE Y + E ++ S ++ HL E P
Sbjct: 311 YIFEVEGKPHSVEEYYLNDLE--HIHHSKLSP---HLLEEPVITKDIYEVAVSLIQMFDD 365
Query: 774 --------------------GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVY 813
+LVFL G EI+ E+L + L + P++
Sbjct: 366 LDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK------RLQVYPLH 419
Query: 814 SALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQ 873
S++ E Q +F PG RK++++TNIAE+S+T+ + YV+D + V + T
Sbjct: 420 SSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQS 479
Query: 874 LVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLK 933
L ++ S+ QR GRAGR G CYRL + + + + VPE+ R L ST+L +K
Sbjct: 480 LRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVK 539
Query: 934 A--MGINDLLSFDFMDAPPMETLITAMEQLYTLGAL------DDE----GLLTRLGRRMA 981
MG L + P + + + L +GAL +DE G LT LGR +A
Sbjct: 540 LLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLA 599
Query: 982 EFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFH-QTEG 1040
+ P+ L K++++ GC +E L I + LS++N F P + + K F ++
Sbjct: 600 QLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKS 659
Query: 1041 DHLTLLAVYNSWKNNKFSNP---------WCYENFIQARSLRRAQDIRKQM 1082
D + L+ + +WK + + W N+IQ + +R ++ +++
Sbjct: 660 DCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEEL 710
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 216 bits (550), Expect = 1e-55
Identities = 143/432 (33%), Positives = 220/432 (50%), Gaps = 54/432 (12%)
Query: 807 LIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYN 866
L +LP+YS L E Q ++F P P G+R V+ATN+AETSLTI GI YVVD G VK++ Y+
Sbjct: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
Query: 867 SKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLA 926
TG+ VT +SQA A QRAGRAGRT PG CYRLY+ + D PEI R +
Sbjct: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVE 706
Query: 927 STVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGL-------------- 972
+L +KA+ + +++F F P +E L+ A E L LGAL
Sbjct: 707 DLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSC 766
Query: 973 -LTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQ- 1030
+T LGR MA FP+ P KML +S GC +TIV+ ++V+ +F D+ A +D+
Sbjct: 767 PITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-EELDRPAASDEE 825
Query: 1031 ------KKAKFHQTE------------GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSL 1072
K+A+ Q + GD + LL + + + +C N ++ +++
Sbjct: 826 LTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAM 885
Query: 1073 RRAQDIRKQML----GIMDRHKLDV-----VSCGKSTVRVQKAICSGFFRNAAKKDPQE- 1122
+ +R Q+ + +L V +++ + +G + A++ E
Sbjct: 886 MEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEE 945
Query: 1123 --------GYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLV 1174
Y+T + V+IHPSS LF PE+VVY E+V TTK YM+ V++++ +W+
Sbjct: 946 MLEDKWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIP 1005
Query: 1175 EFAPAFFKVSDP 1186
P++ + P
Sbjct: 1006 ALLPSYCQFDKP 1017
Score = 177 bits (448), Expect = 7e-44
Identities = 104/245 (42%), Positives = 154/245 (62%), Gaps = 13/245 (5%)
Query: 560 EQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKI-GCTQP 618
E+R LPI ++ +++AV ++ I+IV GETGSGKTTQ+ Q+L EAG++S I G T+P
Sbjct: 247 EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVTEP 306
Query: 619 RRVAAMSVAKRVSEEFGCCLGQEV-GYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLT 677
RRVAA+++++RV++E L Q V Y IR+E + ET IK+MTDG+LL+E D L
Sbjct: 307 RRVAAVAMSQRVAKEMN--LSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLL 364
Query: 678 QYAIIMLDEAHERTIHTDVLFGLLKKTV----QKRQDMKLIVTSATLDAVKFSQ----YF 729
+Y ++++DEAHER+++TD+L GLL + V ++ +KL++ SATL F+Q +
Sbjct: 365 RYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFA 424
Query: 730 YEAPIFTIPGRTYPVEILYTKE-PETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDT 788
P+ + R +PV + + K P DY V +IH P G ILVFLTGQ E+
Sbjct: 425 KPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHA 484
Query: 789 ACEIL 793
C L
Sbjct: 485 LCRRL 489
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 214 bits (544), Expect = 5e-55
Identities = 145/453 (32%), Positives = 235/453 (51%), Gaps = 34/453 (7%)
Query: 753 ETDYLDASLITVM--QIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIIL 810
E D +D +LI + I L E G ILVFL G + I T ++L ++ + +I+
Sbjct: 466 EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSD---KFLII 522
Query: 811 PVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTG 870
P++S +P+ QT++F PPG RK+VIATNIAETS+TID + YV+D G +K+ ++++
Sbjct: 523 PLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNN 582
Query: 871 IDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTT-NVPEIQRTNLASTV 929
I + +S+A AKQR GRAGR PG CY LY R +L +PEI RT L
Sbjct: 583 ISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELC 640
Query: 930 LSLKAMGINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEP 987
L +K + + + F MD P E ++ ++ L L ALD + LT LG +A P+EP
Sbjct: 641 LQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEP 700
Query: 988 MLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALAD-QKKAKFHQTEGDHLTLL 1046
+ KM++ C + +LTI + LS ++ F P K+ +AD ++K T DHLT++
Sbjct: 701 HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVV 760
Query: 1047 AVYNSW-----KNNKFSNPWCYENFIQARSLRRAQDIRKQ----MLG---IMDRHKLDVV 1094
+ W + ++ +C+E F+ + +L+ +++ Q +LG + R+ D
Sbjct: 761 NAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPE 820
Query: 1095 S-CGKSTVRVQKA-ICSGFFRNAAKKDPQEGYRTLI------DQQVVYIHPSSALFNRQP 1146
S ++ KA IC+G + AK G + + +V +HP S +
Sbjct: 821 SNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTD 880
Query: 1147 ---EWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
W++YH + T+ Y+ + T + P L+ F
Sbjct: 881 FHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFF 913
Score = 151 bits (381), Expect = 4e-36
Identities = 86/204 (42%), Positives = 127/204 (62%), Gaps = 12/204 (5%)
Query: 552 KKTQMSILEQ---RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYT 608
KK + +E RE LP Y ++++LV + ++Q+ ++ GETG GKTTQ+TQ++ + Y
Sbjct: 191 KKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD-NYI 249
Query: 609 SRGK-----IGCTQPRRVAAMSVAKRVSEEFG--CCLGQEVGYTIRFED-CTSPETVIKY 660
RGK I CTQPRR++A+SVA+RV+ E C G GY IR + + I Y
Sbjct: 250 ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILY 309
Query: 661 MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL 720
T G++L+ DP L+ + I+LDE HER + +DVL ++K + R D+K+I+ SATL
Sbjct: 310 CTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATL 369
Query: 721 DAVKFSQYFYEAPIFTIPGRTYPV 744
+A KFS+YF P+ IPG T+PV
Sbjct: 370 NAEKFSEYFGNCPMIHIPGFTFPV 393
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 199 bits (506), Expect = 1e-50
Identities = 142/453 (31%), Positives = 225/453 (49%), Gaps = 48/453 (10%)
Query: 753 ETDYLDASLITVM--QIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIIL 810
E D +D +LI + I L E G ILVFL G + I T ++L ++
Sbjct: 466 EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVM------------ 513
Query: 811 PVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTG 870
S QT++F PPG RK+VIATNIAETS+TID + YV+D G +K+ ++++
Sbjct: 514 -----FKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNN 568
Query: 871 IDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTT-NVPEIQRTNLASTV 929
I + +S+A AKQR GRAGR PG CY LY R +L +PEI RT L
Sbjct: 569 ISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELC 626
Query: 930 LSLKAMGINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEP 987
L +K + + + F MD P E ++ ++ L L ALD + LT LG +A P+EP
Sbjct: 627 LQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEP 686
Query: 988 MLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALAD-QKKAKFHQTEGDHLTLL 1046
+ KM++ C + +LTI + LS ++ F P K+ +AD ++K T DHLT++
Sbjct: 687 HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVV 746
Query: 1047 AVYNSW-----KNNKFSNPWCYENFIQARSLRRAQDIRKQ----MLG---IMDRHKLDVV 1094
+ W + ++ +C+E F+ + +L+ +++ Q +LG + R+ D
Sbjct: 747 NAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPE 806
Query: 1095 S-CGKSTVRVQKA-ICSGFFRNAAKKDPQEGYRTLI------DQQVVYIHPSSALFNRQP 1146
S ++ KA IC+G + AK G + + +V +HP S +
Sbjct: 807 SNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTD 866
Query: 1147 ---EWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
W++YH + T+ Y+ + T + P L+ F
Sbjct: 867 FHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFF 899
Score = 151 bits (381), Expect = 4e-36
Identities = 86/204 (42%), Positives = 127/204 (62%), Gaps = 12/204 (5%)
Query: 552 KKTQMSILEQ---RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYT 608
KK + +E RE LP Y ++++LV + ++Q+ ++ GETG GKTTQ+TQ++ + Y
Sbjct: 191 KKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD-NYI 249
Query: 609 SRGK-----IGCTQPRRVAAMSVAKRVSEEFG--CCLGQEVGYTIRFED-CTSPETVIKY 660
RGK I CTQPRR++A+SVA+RV+ E C G GY IR + + I Y
Sbjct: 250 ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILY 309
Query: 661 MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL 720
T G++L+ DP L+ + I+LDE HER + +DVL ++K + R D+K+I+ SATL
Sbjct: 310 CTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATL 369
Query: 721 DAVKFSQYFYEAPIFTIPGRTYPV 744
+A KFS+YF P+ IPG T+PV
Sbjct: 370 NAEKFSEYFGNCPMIHIPGFTFPV 393
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 196 bits (497), Expect = 1e-49
Identities = 140/496 (28%), Positives = 241/496 (48%), Gaps = 68/496 (13%)
Query: 744 VEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLG-- 801
+ I+ ++ + ++A L ++ + PPG ILVFL G EI ++LYE+++S
Sbjct: 818 MSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEI----KMLYEQLQSNSLF 873
Query: 802 --PDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGF 859
+I P++S+L SE Q +F P G K++I+TNIAETS+TID + YV+D G
Sbjct: 874 NNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGK 933
Query: 860 VKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPE 919
+K+K Y++ G++ L T +SQA A QR GRAGR G C+ L+T Y ++L +PE
Sbjct: 934 MKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPE 993
Query: 920 IQRTNLASTVLSLK------AMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLL 973
IQR L L +K A + + S ++ P ++L + +L LGAL + L
Sbjct: 994 IQRVPLEQLCLRIKILEMFSAHNLQSVFS-RLIEPPHTDSLRASKIRLRDLGALTPDERL 1052
Query: 974 TRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKA 1033
T LG +A P++ + K+++ C + LTI + L+ ++ F P DK+ A+QKK
Sbjct: 1053 TPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKL 1112
Query: 1034 KFHQTEGDHLTLLAVYNSWKNN-----KFSNPWCYENFIQARSLRRAQDIRKQML----- 1083
+F D+L LL Y W+ + + S +C +NF+ R L+ +++Q
Sbjct: 1113 EFAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSD 1172
Query: 1084 ---------------------GIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAK-KDPQ 1121
G++D + S ++ + +C+ + N + K P+
Sbjct: 1173 IGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPE 1232
Query: 1122 EGYRTLIDQQV------------------VYIHPSSALF---NRQPEWVVYHELVLTTKE 1160
++ V V+IHPSS + + +++YHE + T++
Sbjct: 1233 GKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRV 1292
Query: 1161 YMREVTTIDPRWLVEF 1176
++R+ + + LV F
Sbjct: 1293 FIRDCSMVSVYPLVLF 1308
Score = 151 bits (382), Expect = 3e-36
Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 4/199 (2%)
Query: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSR----GK 612
SIL++R+SLP ++ +E ++ + +Q++++ G TG GKTTQI Q++ +
Sbjct: 536 SILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVAN 595
Query: 613 IGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLI 672
I CTQPRR++A+SVA+RV++E +G VGY IR E S T + Y T G+LLR
Sbjct: 596 IICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEG 655
Query: 673 DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEA 732
D L + I++DE HERT +D L +LK V +R +++I+ SATL+A FS YF
Sbjct: 656 DTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSC 715
Query: 733 PIFTIPGRTYPVEILYTKE 751
P+ TIPGRT+PV+ + ++
Sbjct: 716 PVITIPGRTFPVDQFFLED 734
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 175 bits (443), Expect = 3e-43
Identities = 142/533 (26%), Positives = 243/533 (45%), Gaps = 60/533 (11%)
Query: 677 TQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFT 736
++Y L+E E TI+ G +KK Q+ + T A D F Q +
Sbjct: 781 SEYCQKFLEEEEEVTINVTSKAGGIKKY----QEYIPVQTGAHADLNPFYQKY------- 829
Query: 737 IPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP------GDILVFLTGQEEIDTAC 790
RT ILY + ++ LI + +L + P G +L+FL G I
Sbjct: 830 -SSRTQHA-ILYMNPHK---INLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLY 884
Query: 791 EILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDG 850
++L + ++ ++S L ++ Q F PPG RK+V+ATNIAET +TI
Sbjct: 885 DLLSNDRRFYSERYK---VIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPD 941
Query: 851 IYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRD 910
+ +V+D G K+ Y+ + + LV T +S+A A QR GRAGR G C+R+YT + +
Sbjct: 942 VVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERF-E 1000
Query: 911 EMLTTNVPEIQRTNLASTVLSLKAMGI---NDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
+ +VPEI R L L + + D LS +D P ++ + AM L +GA
Sbjct: 1001 GFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLS-KALDPPQLQVISNAMNLLRKIGAC 1059
Query: 968 D-DEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQA 1026
+ +E LT LG+ +A P+ + KMLI GC + + T+ ++++ ++ F P ++
Sbjct: 1060 ELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKD 1119
Query: 1027 LADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSN------PWCYENFIQARSLRRAQDIRK 1080
AD K+ + DHLT+ Y WK + +C NF+ SL +D+++
Sbjct: 1120 EADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQ 1179
Query: 1081 QMLGIM--------------DRHKLDVVSCGKSTVRVQKAICSGFFRNAAK------KDP 1120
+++ ++ + ++ + ++ + +G + N K D
Sbjct: 1180 ELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDV 1239
Query: 1121 QEGYRTLID--QQVVYIHPSSALFNRQPE-WVVYHELVLTTKEYMREVTTIDP 1170
E +++ Q +HPSS + Q W++Y E + + Y+RE T I P
Sbjct: 1240 TEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITP 1292
Score = 158 bits (399), Expect = 3e-38
Identities = 82/204 (40%), Positives = 130/204 (63%), Gaps = 10/204 (4%)
Query: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE-----AGYTSRGK 612
+L++R+ LP++K ++ +V+ + +++++V GETGSGK+TQ+ +L E S+
Sbjct: 565 LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCN 624
Query: 613 IGCTQPRRVAAMSVAKRVSEEFGCCLGQE-----VGYTIRFEDCTSPETVIKYMTDGMLL 667
I CTQPRR++A+S+A RV +E GC G GY IR E T + Y T G+LL
Sbjct: 625 IVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLL 684
Query: 668 RECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQ 727
R+ D L+ + +++DE HER++ +D L +LK+ +QKR D+ LI+ SAT+D+ KFS
Sbjct: 685 RKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFST 744
Query: 728 YFYEAPIFTIPGRTYPVEILYTKE 751
YF PI I GR+YPVE+ + ++
Sbjct: 745 YFTHCPILRISGRSYPVEVFHLED 768
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 160 bits (405), Expect = 7e-39
Identities = 112/395 (28%), Positives = 199/395 (50%), Gaps = 23/395 (5%)
Query: 774 GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSR 833
G +L+FL G +EI + + K + + ++S + + Q ++ P G R
Sbjct: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682
Query: 834 KVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGR 893
K++++TNIAETS+T++ + +V+D G VK+K +++ + L + IS+A A QR GRAGR
Sbjct: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742
Query: 894 TGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFM----DAP 949
PG C+RL++ +++ ML PE+ R L L K + + DF+ + P
Sbjct: 743 CRPGICFRLFSRLRFQN-MLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801
Query: 950 PMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIV 1009
P + A++ L T+ A+D LT LG +A+ P+EP L KM++ +V L C + +LTI
Sbjct: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861
Query: 1010 SMLSVQNVFYRP---KDKQALADQKKAKFHQTEGDHLTLLAVYNSW---KNNKFSNPWCY 1063
L+ ++ F P K+A +K DH+ LL + +W +++ + +C
Sbjct: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921
Query: 1064 ENFIQARSLRRAQDIRKQMLGIMDRHKL----------DVVSCGKSTVRVQKAICSGFFR 1113
+NF+ ++ +R Q+LG + DV + ++ V+ A+ +G +
Sbjct: 922 KNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYP 981
Query: 1114 NAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEW 1148
N D + T ++ V HP+S L QP++
Sbjct: 982 NLVHVDRENLVLTGPKEKKVRFHPASVL--SQPQY 1014
Score = 151 bits (381), Expect = 4e-36
Identities = 101/300 (33%), Positives = 166/300 (55%), Gaps = 32/300 (10%)
Query: 465 VKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLP---------- 514
VK DGS + AMM L K A R + P+ NK + LP
Sbjct: 102 VKKKDGSETAHAMMTCNLT---HNTKHAVRSL-IQRFPV-TNKERTELLPKTERGNVFAV 156
Query: 515 DAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQL 574
+AE R+++ G + N IP+ K+ + R+SLP+++ +E++
Sbjct: 157 EAENREMSKTS---GRLNNGIPQIPV-----------KRGESEFDSFRQSLPVFEKQEEI 202
Query: 575 VQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSR--GKIGCTQPRRVAAMSVAKRVSE 632
V+ + +N++++++GETGSGKTTQI Q+L + + + +I CTQPRR+AA++VA+RV+
Sbjct: 203 VKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAA 262
Query: 633 EFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLI-DPDLTQYAIIMLDEAHERT 691
E +GQ +GY IR E SP+T++ + T+G+LLR + D L+ +++DE HER
Sbjct: 263 ERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERD 322
Query: 692 IHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKE 751
+D L L+ +QK +KLI++SA LD F +YF P+ I GR + V+ ++ ++
Sbjct: 323 RFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLED 382
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 87.0 bits (214), Expect = 1e-16
Identities = 49/106 (46%), Positives = 68/106 (64%), Gaps = 7/106 (6%)
Query: 159 QEKQRDAEH---RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRER 215
+EK+R+ E RDR + K+R R RDR RDRDRDRER+ DR+ + RSRSR +SR RER
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRN---KDRSRSREKSRDRER 393
Query: 216 NKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261
+ + R R R R + ++R +R++ ER +R +DK DR EE
Sbjct: 394 ERERERERERERERERERER-EREREREREREREKDKKRDREEDEE 438
Score = 76.3 bits (186), Expect = 2e-13
Identities = 53/161 (32%), Positives = 82/161 (50%), Gaps = 10/161 (6%)
Query: 98 PSTSKD--PVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDDVKVAVDVLKELEALMPS 155
PS D P K K +KE + FPV P ++ ++D+ A+++ ++ L+
Sbjct: 225 PSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYP----LITKEDIN-AIEMEEDKRDLISR 279
Query: 156 AAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRER 215
K RD + +K K+ + R R+RER R+R+ +RR R R R R R RE+
Sbjct: 280 EIS--KFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
Query: 216 NKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
K + R R R R + K+R DRD+ ER+ DR R++ DR
Sbjct: 338 EKERERERERDRDRDRTKER-DRDRDRERDRDRDRERSSDR 377
Score = 75.5 bits (184), Expect = 3e-13
Identities = 40/95 (42%), Positives = 58/95 (61%), Gaps = 6/95 (6%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR---RHRSRSRSRSRTRER 215
+E+ RD + R+R + + R RS DRN+DR R RE++RDR+ +R R R R R R R RER
Sbjct: 355 KERDRDRD-RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERER 413
Query: 216 NKVKSRYRSRSRSQSPPKDRK--DRDKYGERNLDR 248
+ + R R R R + +DR+ + D Y R L+R
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLER 448
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 5/102 (4%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR---RHRSRSRSRSRTRER 215
+EK RD E R+R ++++R R R+R R+R+R+RER R+R+ +R + R R ER
Sbjct: 385 REKSRDRE-REREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 216 NKVKSRYRSRSRS-QSPPKDRKDRDKYGERNLDRWRDKHVDR 256
K++ + R + + Q K+ + R++ R ++ ++ +R
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Score = 51.6 bits (122), Expect = 5e-06
Identities = 27/95 (28%), Positives = 56/95 (58%), Gaps = 3/95 (3%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+E++R+ E R+R ++++R R R+R R+R+R+RE+++ RD + R R+ +
Sbjct: 395 RERERERE-REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453
Query: 219 KSRYRSRSRSQSPPKDRKDR--DKYGERNLDRWRD 251
++ Y+ R ++ + +K R +K ER +R R+
Sbjct: 454 EAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Score = 35.8 bits (81), Expect = 0.26
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 10/86 (11%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERN------RDRDHKRRHRSRS---RSR 209
+E++R+ E R+R +++++ + RDR D + ER R+++ + R ++ R R
Sbjct: 411 RERERERE-REREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469
Query: 210 SRTRERNKVKSRYRSRSRSQSPPKDR 235
+TRE K R R R + R
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKR 495
Score = 31.2 bits (69), Expect = 6.3
Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 14/96 (14%)
Query: 156 AAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRD--RERNR----------DRDHKRRHR 203
AA QE+ ++ E R+R K ++ + +R +R R+ +E R DRD + +R
Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR 514
Query: 204 SRSRSRSRTRERNK-VKSRYRSRSRSQSPPKDRKDR 238
S + R R+R K +++ R R R + ++ + R
Sbjct: 515 G-SALQKRLRDREKEMEADERDRKREKEELEEIRQR 549
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 86.3 bits (212), Expect = 2e-16
Identities = 174/784 (22%), Positives = 309/784 (39%), Gaps = 137/784 (17%)
Query: 163 RDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRY 222
R + RDR ++++RSRSRD+ R R RDR+R R + R RSR R RSR+R+R + +SR
Sbjct: 38 RRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRS 97
Query: 223 RS-RSRSQSPPKD---------RKDRDKYGERNLDRWRDKHVDRPPPEEPTIGDIYNGKV 272
R RSRS SP K++ GE + ++ +DK D+ +E G+ K+
Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD-DKEDEKEKDAGNFDQNKL 156
Query: 273 TSIMQFGCFVQLEGLRKRWEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTGTKTS 332
E +RKR E + E +R+ + N+ ++ + + +K G K S
Sbjct: 157 E-----------EEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMK------QGKKWS 199
Query: 333 LSMKDVDQETGEDLNPNRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLT 392
L D D++ + E NE ++ V EV+ ++ +
Sbjct: 200 LEDDDDDEDDPAEAEK--------EGNEMEGEELDPLDAYMEEVK-EEVKKFNMRSVKGG 250
Query: 393 RISDPEKWEIKQMIAANVLSKEEFPDFDEETGILPKVD-DEEDEDLEIELVEEEPPFLRG 451
++ + + V +K+ D D++ G L + D D + E E V+ +
Sbjct: 251 GGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGY 310
Query: 452 HTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPM-GLN-KHW 509
TKQ + P+ G + ++ + K +Q E + + M G+ K
Sbjct: 311 QTKQRKLLEPV-----DHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGK 365
Query: 510 VDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYK 569
P P Q +M+ + + KKH Y K T
Sbjct: 366 GCPKPIKSWVQCGISMKILNSL-------KKH-------GYEKPT--------------P 397
Query: 570 LKEQLVQAVHDNQILIVIGETGSGKTTQ---------ITQYLAEAGYTSRGKIGCTQ-PR 619
++ Q + A+ + LI I +TGSGKT + Q E G G I P
Sbjct: 398 IQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEG---EGPIAVIMTPT 454
Query: 620 RVAAMSV---AKRVSEEFG---CCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLID 673
R A+ + K+ S+ G C+ G + + + +I T G ++ +
Sbjct: 455 RELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEII-VCTPGRMIDMLAAN 513
Query: 674 ----PDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAV--KFSQ 727
+L + ++LDEA +R +++ R D + ++ SAT ++
Sbjct: 514 SGRVTNLRRVTYVVLDEA-DRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALAR 572
Query: 728 YFYEAPI-FTIPGRTYPV----EILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTG 782
PI + GR+ + + E E +L L+ ++ + + G +++F+
Sbjct: 573 RILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFL--KLLELLGHY--QESGSVIIFVDK 628
Query: 783 QEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIA 842
QE D +L + M++ P + ++ + + I + G+ K+++AT++A
Sbjct: 629 QEHAD---GLLKDLMRASYP------CMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVA 679
Query: 843 ETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTG-PGKCYR 901
L + + VV+ Y+ + V RAGR GR G G Y
Sbjct: 680 ARGLDVKHLILVVN--------YSCPNHYEDYV----------HRAGRTGRAGNKGYAYT 721
Query: 902 LYTE 905
TE
Sbjct: 722 FITE 725
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 79.0 bits (193), Expect = 3e-14
Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRS 206
KE E A +E++R+ E RDR + + R R+R R+R+RDRE+ R+R+ + R R R
Sbjct: 703 KERELERERAREREREREKE-RDRERDRDRDHDRERERERERDREKEREREREERERERE 761
Query: 207 RSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPP 258
R R R RER + + R R R + + +D +D+DK + ++ + DR P
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813
Score = 70.9 bits (172), Expect = 7e-12
Identities = 36/107 (33%), Positives = 62/107 (57%), Gaps = 5/107 (4%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-----RHRSRSRSRSRTRE 214
+ +RD R+R ++++R R R+R R+R+RDRER ++R+ +R R R R + R R R+
Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERD 728
Query: 215 RNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261
R++ R R R R + K+R+ + ER +R R++ +R E
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Score = 68.6 bits (166), Expect = 4e-11
Identities = 35/99 (35%), Positives = 61/99 (61%), Gaps = 4/99 (4%)
Query: 159 QEKQRDAEH-RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNK 217
+E++R+ E R+R K+++ R R R R+R+R++ER+R+RD R H R R R RER++
Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDH---DRERERERERDR 745
Query: 218 VKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
K R R R + + ++R++ ER +R R++ +R
Sbjct: 746 EKEREREREERERERERERERERERERERERARERDKER 784
Score = 66.6 bits (161), Expect = 1e-10
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-RHRSRSRSRSRTRERNK 217
Q + + E +R ++++ R DR +R R+R+R R+RD +R R R R R R R +ER
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 218 VKSRYRSRSRSQSPPKDR---KDRDKYGERNLDRWRDKHVDRPPPEE 261
+ R R R R + +DR +DRD ER +R RD+ +R E
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Score = 61.6 bits (148), Expect = 4e-09
Identities = 39/107 (36%), Positives = 64/107 (59%), Gaps = 9/107 (8%)
Query: 159 QEKQRDAEHRDRTKKKKRSRS-RDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRER-- 215
+E++R+ E RDR K+++R R R+R R+R+R+RER R+R+ R R+R R + R R+R
Sbjct: 735 RERERERE-RDREKEREREREERERERERERERERERERE---RERARERDKERERQRDW 790
Query: 216 -NKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261
+K K R R + + +DR RD + ER + R ++ P P +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERK-SKKRYRNEGSPSPRQ 836
Score = 58.2 bits (139), Expect = 5e-08
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 6/83 (7%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
QE+ R R+R ++++ +R R+ +RD D+D RNRDRD R R R R R R++ +
Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRD-----RLRERERERERDKRRD 1354
Query: 219 KSRYRSRSRSQSPPKDR-KDRDK 240
R R R S S +DR +DRD+
Sbjct: 1355 LDRERERLISDSVERDRDRDRDR 1377
Score = 57.0 bits (136), Expect = 1e-07
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 24/117 (20%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRER--- 215
+E++R+ E R+R ++++R R R+R R+R+R RER+++R+ +R + + R RE+
Sbjct: 747 KEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREE 806
Query: 216 -------------NKVKSRYR---SRSRSQSPPKDRK---DRDKYGERNLDRWRDKH 253
K K RYR S S QSP + R+ D D Y D +KH
Sbjct: 807 IREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSG--DDKNEKH 861
Score = 51.2 bits (121), Expect = 6e-06
Identities = 29/101 (28%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+ + + + RD ++ +R S R++ R+ + ER+ R+ +R R R R RER++
Sbjct: 623 ERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRE 682
Query: 219 KSRYRSRSRSQSPPKDR---KDRDKYGERNLDRWRDKHVDR 256
+ R R R R + +DR K+R+ ER +R R++ +R
Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKER 723
Score = 48.9 bits (115), Expect = 3e-05
Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 3/106 (2%)
Query: 144 DVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHR 203
D L+E + + ++RD R+ + + R+R+RDR R+RER R+RD KRR
Sbjct: 1297 DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD-KRRDL 1355
Query: 204 SRSRSR--SRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLD 247
R R R S + ER++ + R R+ SQ R + GE D
Sbjct: 1356 DRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 126 DNPSVRTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRD-AEHRDRTKKKKRSRSRDRNR 184
D +++ + K +D LK E +++ ++ R + R + ++ SR +
Sbjct: 1234 DREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSF 1293
Query: 185 DRDRDRERNRDRDHKRRHRSRSRSRSRTRE----------RNKVKSRYRSRSRSQSPPKD 234
D RDR + RDR R R R R +R RE RN+ + R R R R + K
Sbjct: 1294 D-SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDK- 1351
Query: 235 RKDRDKYGER----NLDRWRDKHVDR 256
R+D D+ ER +++R RD+ DR
Sbjct: 1352 RRDLDRERERLISDSVERDRDRDRDR 1377
Score = 45.1 bits (105), Expect = 4e-04
Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 42/144 (29%)
Query: 160 EKQRDAEHRDR-TKKKKRSRSRDRNRDR---DRDRERNRDRDHK---------------- 199
E + RDR ++ R ++RD + +R +RDR NR+RD +
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 200 -------------RRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDR---------KD 237
R R+R R R RER++ + R R R R + K+R ++
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 238 RDKYGERNLDRWRDKHVDRPPPEE 261
R++ ER+ +R RD+ DR E
Sbjct: 717 REREKERDRERDRDRDHDRERERE 740
Score = 38.9 bits (89), Expect = 0.030
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDR--DRERNRDRDHKRRHRSRSRSRSRTRERN 216
+E R R++ +++R +D++ RD DRE RD RR +R R R+
Sbjct: 417 REDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRD--RRDARDTRDRRELRDSR 474
Query: 217 KVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDK 252
++ R S+ + R RD R+ +RD+
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510
Score = 38.5 bits (88), Expect = 0.039
Identities = 40/181 (22%), Positives = 74/181 (40%), Gaps = 16/181 (8%)
Query: 90 QTMRPPAKPSTSKDP---VVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDDVKVAVDVL 146
+T+ PP + S S P + P+ ++ + P+ + + RT D
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHD--------- 411
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRS 206
+ E + +++++D+ +R ++ +S SRD DR+ R+R R R
Sbjct: 412 RRHERREDTRGKRDREKDSRE-EREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRREL 470
Query: 207 RSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKH--VDRPPPEEPTI 264
R R+ +++ R S+ P R RD + R+ + RD H D P E +
Sbjct: 471 RDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDRE-GRDTHRKEDTYPEESRSY 529
Query: 265 G 265
G
Sbjct: 530 G 530
Score = 36.2 bits (82), Expect = 0.20
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 17/96 (17%)
Query: 159 QEKQRDAEHRD-RTKKKKRSRSRDRNRDRD-------RDRERNRDRDHKRRHR------- 203
++++ + RD R ++ R SRD RD RD RDR+ + HR
Sbjct: 465 RDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPE 524
Query: 204 -SRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDR 238
SRS R+ RE + ++ R+ SR++S + R DR
Sbjct: 525 ESRSYGRNHLREESS-RTEIRNESRNESRSEIRNDR 559
Score = 33.9 bits (76), Expect = 0.97
Identities = 37/117 (31%), Positives = 50/117 (42%), Gaps = 23/117 (19%)
Query: 163 RDAEHRDRTKKK----KRSRSRDRNRDRD---RDRERNRDRDHKR---RHRSRSRSRSRT 212
RD E RD +K+ + SRS RN R+ R RN R+ R R+ RSR R
Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRV 567
Query: 213 RERNKVKSRYRSRSRSQSPPKDRK------------DRDKYGER-NLDRWRDKHVDR 256
E + SR S+ S + +RD+Y ER N D+ RD +R
Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER 624
Score = 32.3 bits (72), Expect = 2.8
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 172 KKKKRSRSRDRNRDRDRD-RERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQS 230
K K++ + +DR ++ RD ++R RD + +R R + RS S + + S S SQS
Sbjct: 279 KYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQS 338
Score = 31.2 bits (69), Expect = 6.3
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 37/139 (26%)
Query: 147 KELEALMPSAAGQEK----QRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRH 202
+E E A ++K QRD E +D+ + +R + + DR+ R+ + +R K+R+
Sbjct: 768 RERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN-PRDGHDERKSKKRY 826
Query: 203 R-----SRSRSRSRTRERNKVKSRYRS------------------RSRSQSPPKDRKDRD 239
R S +S R RE + Y S SRS SP +DR
Sbjct: 827 RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ 886
Query: 240 KYGERNLDRWRDKHVDRPP 258
RW+++ DR P
Sbjct: 887 -------GRWKEE--DRKP 896
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 78.2 bits (191), Expect = 4e-14
Identities = 62/201 (30%), Positives = 98/201 (48%), Gaps = 46/201 (22%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSR------DRNRDRDRDRERNRDRDHKR 200
KE ++ + + + R+ HR R++++K+SRSR R+R R+R + R+R R+ KR
Sbjct: 56 KERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
Query: 201 RHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPE 260
R RSRSRSRSR R R + +SR RSRSR + K R ++ + R+L R PPP
Sbjct: 116 RIRSRSRSRSRHRHRTRSRSRTRSRSRDR---KKRIEKPRRFSRSLSR-----TPSPPP- 166
Query: 261 EPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISELRRE----------------- 303
+ G+ T++ E L +R E + E R +
Sbjct: 167 -------FRGRNTAM------DAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAAT 213
Query: 304 -GRVANVADVVSKGQRVKVKV 323
G V NVA +++ G +V ++
Sbjct: 214 GGSVLNVAALLASGTQVTPQI 234
Score = 70.9 bits (172), Expect = 7e-12
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 5/99 (5%)
Query: 155 SAAGQEKQRDAEH-RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTR 213
S G+E+ +E+ DR K+K+R SR R+ R R RER H+ R R R +SRSR+R
Sbjct: 36 SDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR----HRSRSRERKKSRSRSR 91
Query: 214 ERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDK 252
ER K +SR R R +S+S ++RK R + R+ R R +
Sbjct: 92 ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
Score = 54.3 bits (129), Expect = 7e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 3/97 (3%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-RHRSRSRSRSRTRERNKV 218
+K + EH D+ + R R + + DR + ++R R R SRSRSR R R R++
Sbjct: 22 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRS 80
Query: 219 KSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHV 254
+ R +SRSRS+ K R + R++ R+ R R + +
Sbjct: 81 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 117
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 10/102 (9%)
Query: 163 RDAEHRDRTKKKKRSR-------SRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRER 215
R E +D++ KK +S S D+ R+R E DR HKR+ R SR RS +R R
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR-HKRKERKSSRGRSHSRSR 70
Query: 216 NKVKSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHVDR 256
++ + R+RSRSR + + R ++R K R+ +R + + R
Sbjct: 71 SRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 111
Score = 40.8 bits (94), Expect = 0.008
Identities = 23/85 (27%), Positives = 39/85 (45%)
Query: 172 KKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSP 231
K+ +R S+D++ + + E N + R R S +R+K K R SR RS S
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 232 PKDRKDRDKYGERNLDRWRDKHVDR 256
+ R+ R + R + R + +R
Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRER 93
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 78.2 bits (191), Expect = 4e-14
Identities = 62/201 (30%), Positives = 98/201 (48%), Gaps = 46/201 (22%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSR------DRNRDRDRDRERNRDRDHKR 200
KE ++ + + + R+ HR R++++K+SRSR R+R R+R + R+R R+ KR
Sbjct: 115 KERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Query: 201 RHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPE 260
R RSRSRSRSR R R + +SR RSRSR + K R ++ + R+L R PPP
Sbjct: 175 RIRSRSRSRSRHRHRTRSRSRTRSRSRDR---KKRIEKPRRFSRSLSR-----TPSPPP- 225
Query: 261 EPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISELRRE----------------- 303
+ G+ T++ E L +R E + E R +
Sbjct: 226 -------FRGRNTAM------DAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAAT 272
Query: 304 -GRVANVADVVSKGQRVKVKV 323
G V NVA +++ G +V ++
Sbjct: 273 GGSVLNVAALLASGTQVTPQI 293
Score = 70.9 bits (172), Expect = 7e-12
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 5/99 (5%)
Query: 155 SAAGQEKQRDAEH-RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTR 213
S G+E+ +E+ DR K+K+R SR R+ R R RER H+ R R R +SRSR+R
Sbjct: 95 SDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR----HRSRSRERKKSRSRSR 150
Query: 214 ERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDK 252
ER K +SR R R +S+S ++RK R + R+ R R +
Sbjct: 151 ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 189
Score = 54.3 bits (129), Expect = 7e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 3/97 (3%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-RHRSRSRSRSRTRERNKV 218
+K + EH D+ + R R + + DR + ++R R R SRSRSR R R R++
Sbjct: 81 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRS 139
Query: 219 KSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHV 254
+ R +SRSRS+ K R + R++ R+ R R + +
Sbjct: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 176
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 148 ELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHK-RRHRSRS 206
E + L P ++ + E + + + S+ +R R R RER R D++ R+HRSRS
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHH-YSRSRSRSRERKRKSDNEGRKHRSRS 65
Query: 207 RSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKH 253
RS+ R +K KS + +S + + D+ + + + D+H
Sbjct: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH 112
Score = 48.9 bits (115), Expect = 3e-05
Identities = 37/113 (32%), Positives = 60/113 (53%), Gaps = 12/113 (10%)
Query: 155 SAAGQEKQRDAEHRDRTKKKKRSRSR-DRNRDRDRDRER-NRDRDHKRRHRSRSR----- 207
S + ++ R E +D++ KK +S D+ D+ RER N + + RH+ + R
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
Query: 208 ---SRSRTRE-RNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
SRSR+RE R++ +SR R +SRS+S + +K R + ER R R + R
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRER-KKSRSRSRERKKSRSRSRERKR 174
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 9/106 (8%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRD--RNRDRDRDRERNRDRDHKRRHRSRSRSRSRTR--- 213
+E++R +++ R K + RSRS++ R+ +D+ ++++ +H + S + R R
Sbjct: 48 RERKRKSDNEGR-KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSE 106
Query: 214 ---ERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
+R+K K R SR RS S + R+ R + R + R + +R
Sbjct: 107 NGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
>gi|41393554 LUC7-like isoform b [Homo sapiens]
Length = 371
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 18/147 (12%)
Query: 139 VKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKR---SRSRDRNRDRDRDRERNRD 195
++ +D L++ A Q++ R E R+R ++ R SR+RDR R R RDR R R
Sbjct: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
Query: 196 RDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDR------- 248
R R R SRSRSR R R R+RSRSRS S R RD+ + R
Sbjct: 281 RSTSRERRKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
Query: 249 -WRDKHVDRPPPEEPTIGDIYNGKVTS 274
W +R PP+ + NGK+ S
Sbjct: 336 SWESGRSERGPPDWRL--ESSNGKMAS 360
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 72.8 bits (177), Expect = 2e-12
Identities = 39/98 (39%), Positives = 60/98 (61%), Gaps = 4/98 (4%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDR--DRERNRDRDHKRRHRSRSRSRSRTRERN 216
+E+ R E ++T+++ R R RDR+R+RDR DRE+ R+R K R R R R R RE
Sbjct: 19 RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERER-QKERDRQRQRERETERETE 77
Query: 217 KVKSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKH 253
+ + R R R R + ++R KDRD+ +R DR R+++
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
Score = 69.7 bits (169), Expect = 2e-11
Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 18/116 (15%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR---------------RHR 203
+E++ E +R +++ R R RDR DR+++RER ++RD +R R R
Sbjct: 25 RERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQR 84
Query: 204 SRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRK---DRDKYGERNLDRWRDKHVDR 256
R R R RER+K + R R R ++ ++RK +RDK ER DR R++ R
Sbjct: 85 QRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQR 140
Score = 64.7 bits (156), Expect = 5e-10
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 168 RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSR 227
R R +K++ R ++ R+RDR RER + + RHR R R R R R+ ++ K R R + R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 228 SQSPPKDR-----------KDRDKYGERNLDRWRDKHVDRPPPEE 261
+ ++R + R + +R DR RDK DR E
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
Score = 64.7 bits (156), Expect = 5e-10
Identities = 38/107 (35%), Positives = 63/107 (58%), Gaps = 9/107 (8%)
Query: 159 QEKQRDAEH-RDRTKKKKRSRSRDRNRDRDR----DRERNRDRDHKRRH---RSRSRSRS 210
++K+RD + R+R +++ R R+R R R+R DRER++DRD +R+ R+R R+R
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 211 RTRERNKVKSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHVDR 256
RER+K R R R R + ++R + R + +R DR R + +R
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
Score = 63.9 bits (154), Expect = 9e-10
Identities = 37/103 (35%), Positives = 61/103 (59%), Gaps = 13/103 (12%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNR----DRDRDRERNRDRDHKR---RHRSRSRSRSRT 212
+++RD + RDR +K++ R+R+RNR +RD+ ER RDR+ +R R R R R R R
Sbjct: 93 DRERDKD-RDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK 151
Query: 213 RERNKVKSRY-----RSRSRSQSPPKDRKDRDKYGERNLDRWR 250
RE ++ + R+ R + R + K+RK++ K +R D+ R
Sbjct: 152 RETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 8/87 (9%)
Query: 158 GQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNK 217
G+E+ + E R+R ++++R R R+R R R R+R+R DR+ +R R + R +ER K
Sbjct: 119 GRERDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKK 177
Query: 218 VKSRYRSRSRSQSPPKDRKDRD-KYGE 243
R + K R+D+ K+GE
Sbjct: 178 ------ERKEKKKEEKRREDKKRKWGE 198
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 70.9 bits (172), Expect = 7e-12
Identities = 37/86 (43%), Positives = 58/86 (67%), Gaps = 5/86 (5%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+E++++AE R+R ++ +R + R+ +R+RDR+RER R+RD R R R R R R RER++
Sbjct: 1261 KEREKEAE-RERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRR 1319
Query: 219 KSRYRSRSRSQSPPKDRKDRDKYGER 244
++ SRSRS+S P RD+ G R
Sbjct: 1320 DTKRHSRSRSRSTPV----RDRGGRR 1341
Score = 57.4 bits (137), Expect = 8e-08
Identities = 34/121 (28%), Positives = 65/121 (53%), Gaps = 14/121 (11%)
Query: 135 DEDDVKVAVDVLKELEAL-----MPSAAGQEKQRDAEHRDRTKKKKRSRS-------RDR 182
+E K+ D+ ++ +A +P Q Q++AE +R K++++ R ++R
Sbjct: 1204 EEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKER 1263
Query: 183 NRDRDRDRERNRDRDHKRRH-RSRSRSRSRTRERNK-VKSRYRSRSRSQSPPKDRKDRDK 240
++ +R+R R +R+ +R H R R R R R RER++ + R R R R + +DR+D +
Sbjct: 1264 EKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKR 1323
Query: 241 Y 241
+
Sbjct: 1324 H 1324
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 16/93 (17%)
Query: 147 KELEALMPSAAGQEKQRDAEH-RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSR 205
+E EA E+++ EH R+R ++++R R RDR DRDRDRER+R+
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRG-DRDRDRERDRE---------- 1311
Query: 206 SRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDR 238
R R R+R K RSRSRS +P +DR R
Sbjct: 1312 ---RGRERDRRDTKRHSRSRSRS-TPVRDRGGR 1340
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/74 (29%), Positives = 43/74 (58%), Gaps = 12/74 (16%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVK 219
E++R+ E R+RT+ + R DR++ R+ R R+R RD +R+ R++S+ + K
Sbjct: 1148 EREREMERRERTRSE---REWDRDKVREGPRSRSRSRDRRRKERAKSKEK---------K 1195
Query: 220 SRYRSRSRSQSPPK 233
S + +++ + P K
Sbjct: 1196 SEKKEKAQEEPPAK 1209
Score = 41.2 bits (95), Expect = 0.006
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Query: 178 RSRDRNRDRD-RDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRK 236
R+ R ++R R++ R+R+ +RR R+RS RE ++ K R RSRS+S + RK
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSE-----REWDRDKVREGPRSRSRSRDRRRK 1186
Query: 237 DRDKYGERNLDRWRDKHVDRPP 258
+R K E+ ++ ++K + PP
Sbjct: 1187 ERAKSKEKKSEK-KEKAQEEPP 1207
Score = 40.8 bits (94), Expect = 0.008
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 152 LMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSR 211
+ P + +QR+ E R + +R R +R R+R R ER DRD K R RSRSRSR
Sbjct: 1125 VQPPQHPRAEQREQERAVREQWAEREREMER-RERTRS-EREWDRD-KVREGPRSRSRSR 1181
Query: 212 TRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLD 247
R R + R++S+ + K K +++ + LD
Sbjct: 1182 DRRRKE-----RAKSKEKKSEKKEKAQEEPPAKLLD 1212
Score = 39.7 bits (91), Expect = 0.018
Identities = 45/188 (23%), Positives = 73/188 (38%), Gaps = 20/188 (10%)
Query: 90 QTMRPPAKPSTSKDPVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDDVKVAVDVLKE- 148
+++ P + ST D + E E + P+ + + ++ + E+ +K KE
Sbjct: 498 ESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEG 557
Query: 149 ---LEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRE------RNRDRDHK 199
L+PS ++ + R + SRSR R+ D R + RD
Sbjct: 558 RRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQA 617
Query: 200 RRHR---------SRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWR 250
R H SRS S SR+R R++ +S + +S SP R Y E D
Sbjct: 618 RTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETK-DPSS 676
Query: 251 DKHVDRPP 258
+ V PP
Sbjct: 677 GQEVATPP 684
Score = 30.8 bits (68), Expect = 8.2
Identities = 24/116 (20%), Positives = 48/116 (41%), Gaps = 15/116 (12%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRD------RERNRDRDHKRRHRSRSRSRSRT 212
+E + + E R K ++ R + R ++++ R + ++ H +R +
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361
Query: 213 R-------ERNKVKSRY--RSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPP 259
+ E ++KS + +S+S SPP+ +DR K L + PPP
Sbjct: 362 KTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPP 417
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 70.9 bits (172), Expect = 7e-12
Identities = 39/101 (38%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 161 KQRDAEHRDRTKKKKRSRSRDRN---RDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNK 217
K D + R+R ++K+R R R++ R+ DR RER R++D RHR R R R R R+R K
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD---RHRKRDRHRERQRDREK 103
Query: 218 VKSRYRSRSRSQSPPKDR---KDRDKYGERNLDRWRDKHVD 255
+ R R R + K+R K+R++ ER +R RD+ D
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Score = 70.5 bits (171), Expect = 9e-12
Identities = 36/102 (35%), Positives = 60/102 (58%), Gaps = 4/102 (3%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-RHRSRSRSRSRTRERNK 217
+ +++ R+ +K++R R +DR+R RDR RER RDR+ +R R R R R R +ERN+
Sbjct: 64 RRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR 123
Query: 218 VKSRYRSRSRSQSPPKDRK---DRDKYGERNLDRWRDKHVDR 256
K R R R +DR+ R++ +R+ ++ R++ DR
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Score = 68.9 bits (167), Expect = 3e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+E+QR+ E R+R + +KR R R+R R+R+R RE RDR+ K R R R R RERN+
Sbjct: 301 RERQRERE-RERERNRKRERERERERERERQRETERDRE-KERERKRKRQTEMDRERNRQ 358
Query: 219 KS----RYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
R R R + +DR+ + ER DR RD+ +R
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER 400
Score = 68.6 bits (166), Expect = 4e-11
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 18/132 (13%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSR--------------SRDRNRDRDRDRER 192
+E E + +++Q D E RDR +K +R R RD+ R+R+RDR+R
Sbjct: 212 RERERETETETERKRQTDRE-RDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 193 NRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDR---KDRDKYGERNLDRW 249
+RDR K R R R R R ER++ R R R R + ++R ++R++ ER +R
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 250 RDKHVDRPPPEE 261
R+ DR E
Sbjct: 331 RETERDREKERE 342
Score = 68.2 bits (165), Expect = 5e-11
Identities = 36/99 (36%), Positives = 57/99 (57%), Gaps = 4/99 (4%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+E+ R E R +K++ R DR R+R R+++R+R RD RHR R R R + RER
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD---RHRERQRDREKERERQTD 110
Query: 219 KSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHVDR 256
+ R R R + ++ K+R ++ ++ GER DR D +R
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Score = 67.8 bits (164), Expect = 6e-11
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 8/108 (7%)
Query: 159 QEKQRDAE-HRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSR-SRTRERN 216
+E+QRDAE R+R ++R R +RNR ++R+RE+NR +RR R R R + ++T +R+
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ---ERRERERQREKENKTEDRH 205
Query: 217 KVKSRYRSRSRSQSPPKDRK---DRDKYGERNLDRWRDKHVDRPPPEE 261
+ R R R R +RK DR++ +R +R R+K +R E
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 67.4 bits (163), Expect = 8e-11
Identities = 39/108 (36%), Positives = 60/108 (55%), Gaps = 7/108 (6%)
Query: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR---RHRSRSRSRSRTRERN 216
E++ D + R+R ++K R R RDR+R+R RDRE+ R+R R R R + R+R + RER
Sbjct: 72 ERETDRK-RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 217 KVKSRYRSRSRSQSPPKDR---KDRDKYGERNLDRWRDKHVDRPPPEE 261
+ R R R ++R +D +K ER DR R + +R +E
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Score = 67.4 bits (163), Expect = 8e-11
Identities = 42/114 (36%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Query: 147 KELEALMPSAAGQEKQRDAEH---RDRTKKK-KRSRSRDRNRDRDRDRERNRDRDHKRRH 202
+E +A A+ +E +RD E RDR + + +R + R+R DR R R RDR+ +R+
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK- 300
Query: 203 RSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
R R R R R RERN+ + R R R R + ++ +RD+ ER R R +DR
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRE-TERDREKERERKRKRQTEMDR 353
Score = 66.2 bits (160), Expect = 2e-10
Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 20/116 (17%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRD-------------HKRRHRSR 205
+E+Q D E RDR ++K+R+R ++R R+ +R+ ER RDR K R R
Sbjct: 105 RERQTDRE-RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 206 SRSRSRTRERNKVKSRYRS------RSRSQSPPKDRKDRDKYGERNLDRWRDKHVD 255
R R R ERN+ K R R R R + K+ K D++ ER +R R++ +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Score = 64.3 bits (155), Expect = 7e-10
Identities = 33/102 (32%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR---RHRSRSRSRSRTRER 215
++K+R+ R +++ R R+R R++DR R+R+R R+ +R + R R R R R+R
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Query: 216 NKVKSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHVDR 256
K ++R + R R +R +DR G+R +R RD +R
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
Score = 64.3 bits (155), Expect = 7e-10
Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKR-RHRSRSRSRSRTRERNK 217
+E+ RD + R K+++R R R R +RDRE R R+ +R R R R R+R R RER +
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
Query: 218 VKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
+ R R R + K+R +R + + +DR R++ R
Sbjct: 324 ERERERQRETERDREKER-ERKRKRQTEMDRERNRQTGR 361
Score = 64.3 bits (155), Expect = 7e-10
Identities = 36/99 (36%), Positives = 58/99 (58%), Gaps = 7/99 (7%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKV 218
+++QR E RDR ++KR R R+R R+R+R+R+R R+R+ R R R R R ER++
Sbjct: 285 RKRQRRTE-RDRETERKRERQRERERERERNRKRERERE-----RERERERQRETERDRE 338
Query: 219 KSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDKHVDR 256
K R R R R ++R + + G R +R R++ +R
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Score = 61.6 bits (148), Expect = 4e-09
Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 7/106 (6%)
Query: 157 AGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERN 216
A +E++R+ E ++ +++ R RDR+RDR ++RER ++D R R + R RE++
Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKD---RDGQRETEKQREREKD 423
Query: 217 KVKSRYRSRSRSQSPPKDR-KDRDKYGERNLDRWRDK---HVDRPP 258
+ R R R R + K R +DR++ +R R R + +V+ PP
Sbjct: 424 RESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPP 469
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/129 (31%), Positives = 65/129 (50%), Gaps = 20/129 (15%)
Query: 144 DVLKELEALMPSAAGQEKQRDAEHRDRTKK-KKRSRSRDRNRDRDRDRERNRDRDHKR-- 200
D +E E + +E+Q D E + +T++ +++ R R++NR R+RER R++++K
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 201 RHRSRSRSRSRTRE------------RNKVKSRYRSRSRSQSPPKDR-----KDRDKYGE 243
RH R R R R RE R + + R R R + ++R +RDK E
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 244 RNLDRWRDK 252
R DR RD+
Sbjct: 264 RERDRDRDR 272
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 11/119 (9%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDR------DRDRERNRDRDHKR 200
KE E +E++R E ++T+ + R R+R R+R +R R+ +R+RD +R
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 201 ---RHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDR 256
R R + R R ER + + R R R + +DR+ +++ ER DR R + +R
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER--ERQTDRKRQRRTER 293
Score = 58.2 bits (139), Expect = 5e-08
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSRDRNR--DRDRDRERNRDRD-HKRRHRSRSRSRSRTRER 215
+EK R + RDR ++++R R ++R R DR+RDR+R ++R+ K R R R R R+R
Sbjct: 83 REKDRHRK-RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
Query: 216 NKVKSRYRSRSRSQSPPKDR---KDRDKYGERNLDRWRDKHVDRPPPEE 261
R R R R ++R ++R + ERN + R++ +R E
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Score = 57.8 bits (138), Expect = 6e-08
Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Query: 162 QRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSR 221
Q R + K + DR R+R ++RER R++ R R R R R ++R++ + R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 222 YRSRSRSQSPPKDR-----KDRDKYGERNLDRWRDKHVDR 256
+R R R + ++R +DR + ERN + R++ +R
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETER 133
Score = 57.0 bits (136), Expect = 1e-07
Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 30/127 (23%)
Query: 159 QEKQRDAEHRDRTKKKKRSRSR----------------------DRNRDRDRDRERNRDR 196
+E+QR+ E RDR K+++R R R +R R+R+RDR+ R+R
Sbjct: 327 RERQRETE-RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Query: 197 DHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDR-------KDRDKYGERNLDRW 249
+ + R R R R + R R+ K + R + + KDR + R++ ++ +R
Sbjct: 386 EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445
Query: 250 RDKHVDR 256
R++ DR
Sbjct: 446 RERQTDR 452
Score = 56.6 bits (135), Expect = 1e-07
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 10/109 (9%)
Query: 155 SAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRS-RSRSRSRTR 213
S G+E++R+ E T++K+++ DR RDR R ER R++ +R S R R + R
Sbjct: 206 SERGRERERERETETETERKRQT---DRERDRQRKTEREREKQAERERASERETERDKER 262
Query: 214 ERNKVKSRYRS-RSRSQSPPKDRK-----DRDKYGERNLDRWRDKHVDR 256
ER + + R R R + + DRK +RD+ ER +R R++ +R
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Score = 56.6 bits (135), Expect = 1e-07
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 147 KELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRS 206
+E E + +E++ RDR ++K+R R +++RD R+ E+ R+R+ K R R
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE-KDRESERG 429
Query: 207 RSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY 241
R R R RE+ K + R R R + + RK Y
Sbjct: 430 RERGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
Score = 37.4 bits (85), Expect = 0.088
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 181 DRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDK 240
D +R R +E R R + H+ RERN+ K R R R + Q+ + + R++
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRER 81
Query: 241 YGERNLDRWRDKHVDRPPPEE 261
E++ R RD+H +R E
Sbjct: 82 RREKDRHRKRDRHRERQRDRE 102
Score = 35.0 bits (79), Expect = 0.44
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 159 QEKQRDAEH-----RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTR 213
+EK R++E R+R K+K R R R+R DR R+R R + +RS
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQS 479
Query: 214 ERNKVKSRYRSRSRSQSP 231
+ N+ R +S + P
Sbjct: 480 DPNRPTRGIRWKSSPEDP 497
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,247,192
Number of Sequences: 37866
Number of extensions: 2115356
Number of successful extensions: 20527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 9468
Number of HSP's gapped (non-prelim): 3911
length of query: 1220
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1106
effective length of database: 13,930,794
effective search space: 15407458164
effective search space used: 15407458164
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.