BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 precursor [Homo sapiens] (439 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 945 0.0 gi|93141003 testican 3 isoform 1 [Homo sapiens] 484 e-137 gi|93141001 testican 3 isoform 2 [Homo sapiens] 479 e-135 gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 375 e-104 gi|115298674 nidogen 1 precursor [Homo sapiens] 64 4e-10 gi|68448544 CD74 antigen isoform a [Homo sapiens] 61 2e-09 gi|62243068 insulin-like growth factor binding protein 3 isoform... 55 1e-07 gi|62243248 insulin-like growth factor binding protein 3 isoform... 55 1e-07 gi|144953895 nidogen 2 precursor [Homo sapiens] 54 4e-07 gi|55770862 thyroglobulin [Homo sapiens] 52 8e-07 gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 52 1e-06 gi|190194423 SPARC-like 1 [Homo sapiens] 52 1e-06 gi|190341024 SPARC-like 1 [Homo sapiens] 52 1e-06 gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 52 1e-06 gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 51 2e-06 gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] 51 2e-06 gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 50 3e-06 gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 50 3e-06 gi|54873613 agrin [Homo sapiens] 47 3e-05 gi|197313714 sparc/osteonectin, cwcv and kazal-like domains prot... 46 8e-05 gi|4504615 insulin-like growth factor binding protein 1 precurso... 45 2e-04 gi|62243290 insulin-like growth factor binding protein 4 precurs... 44 4e-04 gi|218505670 epithelial cell adhesion molecule precursor [Homo s... 43 6e-04 gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 42 0.001 gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 42 0.001 gi|28212222 WFIKKN2 protein [Homo sapiens] 42 0.001 gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 42 0.001 gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 41 0.002 gi|5901956 follistatin-like 1 precursor [Homo sapiens] 40 0.003 gi|56090548 insulin-like growth factor binding protein-like 1 [H... 40 0.005 >gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 precursor [Homo sapiens] Length = 439 Score = 945 bits (2442), Expect = 0.0 Identities = 439/439 (100%), Positives = 439/439 (100%) Query: 1 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF 60 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF Sbjct: 1 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF 60 Query: 61 RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120 RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG Sbjct: 61 RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120 Query: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC Sbjct: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 Query: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS 240 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS Sbjct: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS 240 Query: 241 ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE 300 ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE Sbjct: 241 ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE 300 Query: 301 WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK 360 WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK Sbjct: 301 WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK 360 Query: 361 YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV 420 YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV Sbjct: 361 YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV 420 Query: 421 TEDDEDEDDDKEDEVGYIW 439 TEDDEDEDDDKEDEVGYIW Sbjct: 421 TEDDEDEDDDKEDEVGYIW 439 >gi|93141003 testican 3 isoform 1 [Homo sapiens] Length = 433 Score = 484 bits (1247), Expect = e-137 Identities = 231/430 (53%), Positives = 288/430 (66%), Gaps = 13/430 (3%) Query: 5 AVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDK-YWNRFRDD 63 AVL AAAWC + + A AGG GNFLD+ QWL+T+SQYD++ WN+FRDD Sbjct: 6 AVLCVCAAAWCSQSLAAAAAVAAAGGRSDG-GNFLDDKQWLTTISQYDKEVGQWNKFRDD 64 Query: 64 DYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVA 123 DYFR W+P KPFDQALDP+KDPCLK+KCS HKVC+ QD QTA+C+S + L R K+ V Sbjct: 65 DYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEAGVD 124 Query: 124 QKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCL 183 + W GP L CK CPV + VCGSDGH+Y+ +CKLE+ AC GK ++ C+G CPC Sbjct: 125 HRQWRGPI-LSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCP 183 Query: 184 PEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKP-TSSNTAQGRFDTSIL 242 + + + AC+D E R +A+RL+DWF ALHE ++ K T + RFDTSIL Sbjct: 184 SDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSIL 243 Query: 243 PICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWC 302 PICKDSLGWMFN+LD NYDLLLD SE+ +IYLDK E C K FNSCD++KD +SNNEWC Sbjct: 244 PICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWC 303 Query: 303 YCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYG 362 YCFQ+ PCQ E++ IQK K LLG +IP C+E+GYYK TQCHGS GQCWCVD+YG Sbjct: 304 YCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYG 363 Query: 363 NELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTE 422 NE+ GSR G C + E SGDF SG DD + E ++ + E + + Sbjct: 364 NEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE---------IED 414 Query: 423 DDEDEDDDKE 432 DDEDE DD + Sbjct: 415 DDEDEGDDDD 424 >gi|93141001 testican 3 isoform 2 [Homo sapiens] Length = 436 Score = 479 bits (1233), Expect = e-135 Identities = 231/433 (53%), Positives = 288/433 (66%), Gaps = 16/433 (3%) Query: 5 AVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDK-YWNRFRD- 62 AVL AAAWC + + A AGG GNFLD+ QWL+T+SQYD++ WN+FRD Sbjct: 6 AVLCVCAAAWCSQSLAAAAAVAAAGGRSDG-GNFLDDKQWLTTISQYDKEVGQWNKFRDE 64 Query: 63 --DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120 DDYFR W+P KPFDQALDP+KDPCLK+KCS HKVC+ QD QTA+C+S + L R K+ Sbjct: 65 VEDDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEA 124 Query: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 V + W GP L CK CPV + VCGSDGH+Y+ +CKLE+ AC GK ++ C+G C Sbjct: 125 GVDHRQWRGPI-LSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHC 183 Query: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKP-TSSNTAQGRFDT 239 PC + + + AC+D E R +A+RL+DWF ALHE ++ K T + RFDT Sbjct: 184 PCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDT 243 Query: 240 SILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNN 299 SILPICKDSLGWMFN+LD NYDLLLD SE+ +IYLDK E C K FNSCD++KD +SNN Sbjct: 244 SILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNN 303 Query: 300 EWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVD 359 EWCYCFQ+ PCQ E++ IQK K LLG +IP C+E+GYYK TQCHGS GQCWCVD Sbjct: 304 EWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVD 363 Query: 360 KYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRA 419 +YGNE+ GSR G C + E SGDF SG DD + E ++ + E Sbjct: 364 RYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE--------- 414 Query: 420 VTEDDEDEDDDKE 432 + +DDEDE DD + Sbjct: 415 IEDDDEDEGDDDD 427 >gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 2 [Homo sapiens] Length = 424 Score = 375 bits (963), Expect = e-104 Identities = 202/445 (45%), Positives = 269/445 (60%), Gaps = 42/445 (9%) Query: 4 IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62 + +LAAAA A DA G GNF++++QWLS++SQY + K+WNRFRD Sbjct: 13 LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63 Query: 63 ---DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKK 119 DDY ++W N+ D+ALD +KDPC KVKCS HKVC+ Q YQ A+C+SRK L R K+ Sbjct: 64 EVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQ 123 Query: 120 GNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGP 179 V G + + CKPC +AQ A VCGSDGH+Y+S CKLE AC + K LA C+GP Sbjct: 124 PTVKLH---GNKDSI-CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGP 179 Query: 180 CPCLPEPEPPKHK-AERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFD 238 CPC E + CT ++L +L RL+DWF LHE++ + +S D Sbjct: 180 CPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLD 239 Query: 239 TSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSN 298 S+ CKDS+GWMF+KLD + DL LD +E+ AI LDKYE CI+P FNSCD++KDG++S Sbjct: 240 KSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVST 299 Query: 299 NEWCYCF--QKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCW 356 EWC+CF +KP PC E+ RIQ K G FIP C+E+GYY+ QC S+G CW Sbjct: 300 AEWCFCFWREKP---PCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCW 356 Query: 357 CVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVH 416 CVD+ G EL G+R G+ C++ SGDFGSG +G +D+E K Sbjct: 357 CVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSG--------------VGWEDEEEK---E 399 Query: 417 TRAVTEDDEDEDDD--KEDEVGYIW 439 T E+ E+E+ + + D+ GYIW Sbjct: 400 TEEAGEEAEEEEGEAGEADDGGYIW 424 >gi|115298674 nidogen 1 precursor [Homo sapiens] Length = 1247 Score = 63.5 bits (153), Expect = 4e-10 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 28/95 (29%) Query: 303 YCFQKPGGLPCQ--------------NEMNRIQKLSKGKSLLGA--------------FI 334 +C+ PG CQ E+ + + + + +LGA F+ Sbjct: 816 FCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFV 875 Query: 335 PRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSR 369 P C+ G+Y TQCHGSTG CWCVD+ G E+ G+R Sbjct: 876 PECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR 910 >gi|68448544 CD74 antigen isoform a [Homo sapiens] Length = 296 Score = 60.8 bits (146), Expect = 2e-09 Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 19/107 (17%) Query: 306 QKPGGLP------CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVD 359 QKP P CQ E++ I + G +F P+C+E G Y QC+GS G CWCV Sbjct: 200 QKPTDAPPKVLTKCQEEVSHIPAVHPG-----SFRPKCDENGNYLPLQCYGSIGYCWCVF 254 Query: 360 KYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGP 406 G E+ +R +G +C E E D SG V +++LGP Sbjct: 255 PNGTEVPNTRSRGHHNCSESLELE-DPSSGLGVT-------KQDLGP 293 >gi|62243068 insulin-like growth factor binding protein 3 isoform b precursor [Homo sapiens] Length = 291 Score = 55.1 bits (131), Expect = 1e-07 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Query: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364 PC+ EM K ++L G IP C+++G+YK QC S G+ CWCVDKYG Sbjct: 212 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271 Query: 365 LAGSRKQG 372 L G +G Sbjct: 272 LPGYTTKG 279 >gi|62243248 insulin-like growth factor binding protein 3 isoform a precursor [Homo sapiens] Length = 297 Score = 55.1 bits (131), Expect = 1e-07 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Query: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364 PC+ EM K ++L G IP C+++G+YK QC S G+ CWCVDKYG Sbjct: 218 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277 Query: 365 LAGSRKQG 372 L G +G Sbjct: 278 LPGYTTKG 285 >gi|144953895 nidogen 2 precursor [Homo sapiens] Length = 1375 Score = 53.5 bits (127), Expect = 4e-07 Identities = 20/36 (55%), Positives = 28/36 (77%) Query: 334 IPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSR 369 IP+C+E+G + QCHGSTG CWCVD G+E+ G++ Sbjct: 960 IPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQ 995 Score = 52.0 bits (123), Expect = 1e-06 Identities = 18/39 (46%), Positives = 28/39 (71%) Query: 333 FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371 ++P+C++ G++ QCHG + CWCVDK G E+ G+R Q Sbjct: 1039 YVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQ 1077 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 52.4 bits (124), Expect = 8e-07 Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 6/75 (8%) Query: 312 PCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371 P + E+ R S G ++P C G Y+A QC + G CWCVD G E+ G+R+Q Sbjct: 298 PTKCEVERFTATSFGHP----YVPSCRRNGDYQAVQCQ-TEGPCWCVDAQGKEMHGTRQQ 352 Query: 372 G-AVSCEEEQETSGD 385 G SC E Q + + Sbjct: 353 GEPPSCAEGQSCASE 367 Score = 50.4 bits (119), Expect = 3e-06 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 7/53 (13%) Query: 333 FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGA-----VSCEEEQ 380 F+P C EG Y+ QC +G+CWCV+ +G EL GSR +G CE+++ Sbjct: 616 FVPSCTTEGSYEDVQCF--SGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQR 666 Score = 50.4 bits (119), Expect = 3e-06 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Query: 281 IKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLL---GAFIPRC 337 + PLF ++F + L +++ L S G S L G ++P+C Sbjct: 972 LPPLFPPREAFAEQFLRGSDYAIRLAAQSTLSFYQRRRFSPDDSAGASALLRSGPYMPQC 1031 Query: 338 NEEGYYKATQCHGSTGQCWCVDKYGNELAGS 368 + G ++ QCH TG CWCVD+ G + GS Sbjct: 1032 DAFGSWEPVQCHAGTGHCWCVDEKGGFIPGS 1062 Score = 46.6 bits (109), Expect = 4e-05 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%) Query: 333 FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQG-AVSC 376 ++P+C E+G ++ QC CWCV G+E+ GSR+ G V+C Sbjct: 48 YVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVAC 92 Score = 45.8 bits (107), Expect = 8e-05 Identities = 21/60 (35%), Positives = 31/60 (51%) Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQG 372 CQ + +I S +++P+C + G Y QC QCWCVD G E+ G+R+ G Sbjct: 96 CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLG 155 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 10/68 (14%) Query: 309 GGLP-----CQNEMNRIQKLSKGKSLLGA--FIPRCNEEGYYKATQCHGSTGQCWCVDKY 361 GG P C+ + R+Q L G G+ F+P C EG++ QC S +C+CVD Sbjct: 653 GGQPRCPTDCEKQRARMQSLM-GSQPAGSTLFVPACTSEGHFLPVQCFNS--ECYCVDAE 709 Query: 362 GNELAGSR 369 G + G+R Sbjct: 710 GQAIPGTR 717 Score = 40.4 bits (93), Expect = 0.003 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCN-EEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371 C + N ++ + + ++P C E+G + QC + G CWCV G E+ G+R Sbjct: 1145 CPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVT 1204 Query: 372 GA-VSCE 377 G +CE Sbjct: 1205 GGQPACE 1211 Score = 31.2 bits (69), Expect = 1.9 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 6/36 (16%) Query: 349 HGSTGQCWCVDKYGNELAGSRKQGAV------SCEE 378 H CWCVD+ G EL G R + + SCEE Sbjct: 892 HFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEE 927 Score = 29.6 bits (65), Expect = 5.7 Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 25/81 (30%) Query: 299 NEWCYCFQKPGGL----------------PCQNE-----MNRIQKLSKGKSLL----GAF 333 N CYC G PCQ + + +Q L S+L + Sbjct: 700 NSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTY 759 Query: 334 IPRCNEEGYYKATQCHGSTGQ 354 IP+C+ +G ++ QC+G Q Sbjct: 760 IPQCSTDGQWRQVQCNGPPEQ 780 Score = 29.6 bits (65), Expect = 5.7 Identities = 11/30 (36%), Positives = 19/30 (63%) Query: 336 RCNEEGYYKATQCHGSTGQCWCVDKYGNEL 365 +C++ G Y+A+Q +G+ +CVD G L Sbjct: 1522 QCDQNGQYRASQKDRGSGKAFCVDGEGRRL 1551 >gi|11321593 insulin-like growth factor binding protein 6 [Homo sapiens] Length = 240 Score = 51.6 bits (122), Expect = 1e-06 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 8/73 (10%) Query: 312 PCQNEMNRIQKLSKGKSLLGA---FIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364 PC+ ++ + + + + GA ++P C+ G+Y+ QC S GQ CWCVD+ G Sbjct: 162 PCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKS 221 Query: 365 LAGSRK-QGAVSC 376 L GS G+ SC Sbjct: 222 LPGSPDGNGSSSC 234 >gi|190194423 SPARC-like 1 [Homo sapiens] Length = 664 Score = 51.6 bits (122), Expect = 1e-06 Identities = 58/225 (25%), Positives = 84/225 (37%), Gaps = 49/225 (21%) Query: 118 KKGNVAQKHWVGPSNLVKCKP--CPVAQSA-MVCGSDGHSYTSKCKLEFHAC-----STG 169 K+G++ + G + V P CP + VCG+D +Y S C L C G Sbjct: 439 KRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKG 498 Query: 170 KSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWF--------------- 214 L G C +P CTD E+ R++DW Sbjct: 499 HQLQLDYFGACKSIP------------TCTDFEVIQFPLRMRDWLKNILMQLYEANSEHA 546 Query: 215 GALHE-DANRVIKPTSSNTAQGRFDTSILPICKD----------SLGWMFNKLDMN-YDL 262 G L+E N+V K D I + +D + W F++LD + D Sbjct: 547 GYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDR 606 Query: 263 LLDPSEINAI--YLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCF 305 +L SE+ + L E CI F CD KD ++ EW +CF Sbjct: 607 VLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCF 651 >gi|190341024 SPARC-like 1 [Homo sapiens] Length = 664 Score = 51.6 bits (122), Expect = 1e-06 Identities = 58/225 (25%), Positives = 84/225 (37%), Gaps = 49/225 (21%) Query: 118 KKGNVAQKHWVGPSNLVKCKP--CPVAQSA-MVCGSDGHSYTSKCKLEFHAC-----STG 169 K+G++ + G + V P CP + VCG+D +Y S C L C G Sbjct: 439 KRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKG 498 Query: 170 KSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWF--------------- 214 L G C +P CTD E+ R++DW Sbjct: 499 HQLQLDYFGACKSIP------------TCTDFEVIQFPLRMRDWLKNILMQLYEANSEHA 546 Query: 215 GALHE-DANRVIKPTSSNTAQGRFDTSILPICKD----------SLGWMFNKLDMN-YDL 262 G L+E N+V K D I + +D + W F++LD + D Sbjct: 547 GYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDR 606 Query: 263 LLDPSEINAI--YLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCF 305 +L SE+ + L E CI F CD KD ++ EW +CF Sbjct: 607 VLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCF 651 >gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] Length = 457 Score = 51.6 bits (122), Expect = 1e-06 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGS 368 C E Q+ ++ K FIP CN++G Y QCH TG CWCV G ++G+ Sbjct: 90 CVAERKYTQEQAR-KEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGT 144 Score = 43.1 bits (100), Expect = 5e-04 Identities = 19/46 (41%), Positives = 21/46 (45%) Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCV 358 C E + +K IP C G YK QCH STG CWCV Sbjct: 227 CDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCV 272 >gi|10834982 insulin-like growth factor binding protein 5 [Homo sapiens] Length = 272 Score = 51.2 bits (121), Expect = 2e-06 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 7/63 (11%) Query: 312 PCQNEMNR-IQKLSKGKSLL--GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364 PC+ M +Q+L ++ ++P C+ +G+YK QC S G+ CWCVDKYG + Sbjct: 191 PCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMK 250 Query: 365 LAG 367 L G Sbjct: 251 LPG 253 >gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] Length = 303 Score = 50.8 bits (120), Expect = 2e-06 Identities = 57/257 (22%), Positives = 88/257 (34%), Gaps = 67/257 (26%) Query: 82 SKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPV 141 +++PC C KVC + T +CV + P++ P P+ Sbjct: 68 AENPCQNHHCKHGKVCELDENNTPMCVCQ------------------DPTSC----PAPI 105 Query: 142 AQSAMVCGSDGHSYTSKC-----KLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERS 196 + VC +D ++ S C K G L GPC +P Sbjct: 106 GEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIP------------ 153 Query: 197 ACTDKELRNLASRLKDWFGAL-------HEDAN--------RVIKPTSSNTAQGRFDTSI 241 C D EL R++DW + ED N RV K + D + Sbjct: 154 PCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPV 213 Query: 242 LPICKD----------SLGWMFNKLDMN-YDLLLDPSEINAIY--LDKYEPCIKPLFNSC 288 + +D + W F +LD + D L +E+ + L E C F +C Sbjct: 214 ELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETC 273 Query: 289 DSFKDGKLSNNEWCYCF 305 D D ++ +EW CF Sbjct: 274 DLDNDKYIALDEWAGCF 290 >gi|78190498 secreted modular calcium-binding protein 1 isoform 1 [Homo sapiens] Length = 435 Score = 50.4 bits (119), Expect = 3e-06 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 317 MNRIQKLSKGKSLLGA-FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVS 375 + R Q L + K A F+P C E+G + QCH TG CWCV G ++GS Q Sbjct: 97 LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156 Query: 376 CEEEQETSGDFGSGGS 391 T G S Sbjct: 157 VCSGSVTDKPLSQGNS 172 Score = 48.5 bits (114), Expect = 1e-05 Identities = 77/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%) Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSAC 198 C Q +C SDG SY S C+ + C +L + G C + K + ER+ Sbjct: 47 CSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCK---DAGQSKCRLERAQA 102 Query: 199 TDKELRNLASRLKDWFGALHEDANRVI-----------------KPTSSNTAQGRFDTSI 241 ++ + + G ED + KP S ++ Q + Sbjct: 103 LEQAKKPQEAVFVPECG---EDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK----- 154 Query: 242 LPICKDSL-------GWMFNKLD-------MNYDLLLDPSEINAIYLDKYEPCIKPLFNS 287 P+C S+ G K D M + D EI A L IK L Sbjct: 155 TPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTL-----WIKHLVIK 209 Query: 288 CDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQ 347 + + N+E Y C E + ++ G IP C G YK Q Sbjct: 210 DSKLNNTNIRNSEKVYS--------CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQ 261 Query: 348 CHGSTGQCWCV-DKYGNELAG-SRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELG 405 CH STG CWCV G L G S + SCE + + DD +REL Sbjct: 262 CHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD--------ARAKTTEADDPFKDREL- 312 Query: 406 PKDKEGK 412 P EGK Sbjct: 313 PGCPEGK 319 >gi|11545873 secreted modular calcium-binding protein 1 isoform 2 [Homo sapiens] Length = 434 Score = 50.4 bits (119), Expect = 3e-06 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 317 MNRIQKLSKGKSLLGA-FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVS 375 + R Q L + K A F+P C E+G + QCH TG CWCV G ++GS Q Sbjct: 97 LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156 Query: 376 CEEEQETSGDFGSGGS 391 T G S Sbjct: 157 VCSGSVTDKPLSQGNS 172 Score = 48.5 bits (114), Expect = 1e-05 Identities = 77/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%) Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSAC 198 C Q +C SDG SY S C+ + C +L + G C + K + ER+ Sbjct: 47 CSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCK---DAGQSKCRLERAQA 102 Query: 199 TDKELRNLASRLKDWFGALHEDANRVI-----------------KPTSSNTAQGRFDTSI 241 ++ + + G ED + KP S ++ Q + Sbjct: 103 LEQAKKPQEAVFVPECG---EDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK----- 154 Query: 242 LPICKDSL-------GWMFNKLD-------MNYDLLLDPSEINAIYLDKYEPCIKPLFNS 287 P+C S+ G K D M + D EI A L IK L Sbjct: 155 TPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTL-----WIKHLVIK 209 Query: 288 CDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQ 347 + + N+E Y C E + ++ G IP C G YK Q Sbjct: 210 DSKLNNTNIRNSEKVYS--------CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQ 261 Query: 348 CHGSTGQCWCV-DKYGNELAG-SRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELG 405 CH STG CWCV G L G S + SCE + + DD +REL Sbjct: 262 CHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD--------ARAKTTEADDPFKDREL- 312 Query: 406 PKDKEGK 412 P EGK Sbjct: 313 PGCPEGK 319 >gi|54873613 agrin [Homo sapiens] Length = 2045 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 3/45 (6%) Query: 139 CP---VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 CP VA + VCGSDGH+Y S+C L HAC+ SL GPC Sbjct: 555 CPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPC 599 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/110 (32%), Positives = 46/110 (41%), Gaps = 31/110 (28%) Query: 82 SKDPCLKVKCSPHKVCV-TQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140 S+DPC V CS C + D TA C L P +G Sbjct: 244 SRDPCSNVTCSFGSTCARSADGLTASC-----LCPATCRG-------------------- 278 Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC-PC---LPEP 186 A VCGSDG Y +C+L AC+ +++ DGPC PC LP+P Sbjct: 279 -APEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDP 327 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 8/70 (11%) Query: 120 GNVAQKHWVGP---SNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLC 176 G V + + GP S + K PCP + A VCGSD +Y+++C+L+ CS + + L Sbjct: 180 GAVCEPNAEGPGRASCVCKKSPCP-SVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLS 238 Query: 177 DGPC----PC 182 GPC PC Sbjct: 239 RGPCGSRDPC 248 Score = 43.1 bits (100), Expect = 5e-04 Identities = 18/42 (42%), Positives = 26/42 (61%) Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 CP A + VCGSDG +Y ++C+L+ AC G ++ GPC Sbjct: 928 CPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPC 969 Score = 42.4 bits (98), Expect = 8e-04 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 28/101 (27%) Query: 80 DPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPC 139 D + PCL V+C+ C ++ Q A +C Sbjct: 462 DQAPSPCLGVQCAFGATCAVKNGQAAC----------------------------ECLQA 493 Query: 140 PVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 + VCGSDG +Y S C+LE AC+ G+ + GPC Sbjct: 494 CSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPC 534 Score = 35.8 bits (81), Expect = 0.079 Identities = 14/42 (33%), Positives = 23/42 (54%) Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 C + VCGSDG +Y+++C+L+ C + + L G C Sbjct: 709 CQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750 Score = 35.0 bits (79), Expect = 0.14 Identities = 17/45 (37%), Positives = 20/45 (44%) Query: 136 CKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 C C VCGSDG +Y S C+L AC + GPC Sbjct: 620 CPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPC 664 Score = 34.7 bits (78), Expect = 0.18 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Query: 130 PSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPE-PEP 188 P L++ + CP A+ A VCG DG +Y + C + + G L + G C + PEP Sbjct: 340 PEMLLRPESCP-ARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEP 398 Query: 189 PKHKA 193 + A Sbjct: 399 CRFNA 403 Score = 32.0 bits (71), Expect = 1.1 Identities = 13/40 (32%), Positives = 19/40 (47%) Query: 147 VCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEP 186 VC DG +Y S C + C +++ + GPC P P Sbjct: 428 VCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSP 467 >gi|197313714 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 1 [Homo sapiens] Length = 77 Score = 45.8 bits (107), Expect = 8e-05 Identities = 26/60 (43%), Positives = 36/60 (60%), Gaps = 10/60 (16%) Query: 4 IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62 + +LAAAA A DA G GNF++++QWLS++SQY + K+WNRFRD Sbjct: 13 LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63 >gi|4504615 insulin-like growth factor binding protein 1 precursor [Homo sapiens] Length = 259 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 12/78 (15%) Query: 312 PCQNEMNRI-QKLSKGKSLLGA-----FIPRCNEEGYYKATQCH----GSTGQCWCVDKY 361 PC+ E+ R+ + L+K + G ++P CN+ G+Y + QC G G CWCV + Sbjct: 175 PCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPW 234 Query: 362 -GNELAGSRK-QGAVSCE 377 G + GS + +G +C+ Sbjct: 235 NGKRIPGSPEIRGDPNCQ 252 >gi|62243290 insulin-like growth factor binding protein 4 precursor [Homo sapiens] Length = 258 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 12/78 (15%) Query: 313 CQNEMNR-IQKLSKGKS-----LLGAFIPRCNEEGYYKATQCH----GSTGQCWCVD-KY 361 CQ+E++R +++L+ +S L IP C+ G + QCH G G+CWCVD K Sbjct: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233 Query: 362 GNELAGS-RKQGAVSCEE 378 G +L G +G + C + Sbjct: 234 GVKLPGGLEPKGELDCHQ 251 >gi|218505670 epithelial cell adhesion molecule precursor [Homo sapiens] Length = 314 Score = 42.7 bits (99), Expect = 6e-04 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 3/52 (5%) Query: 331 GAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQET 382 G + P C+E G +KA QC+G T CWCV+ G + + K ++C E T Sbjct: 93 GLYDPDCDESGLFKAKQCNG-TSMCWCVNTAG--VRRTDKDTEITCSERVRT 141 >gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] Length = 317 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 23/98 (23%) Query: 83 KDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVA 142 K C V C CV A CV+ + P P + Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPE-----------------------PAS 201 Query: 143 QSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 +CG+DG +Y+S C L C G+S+ +G C Sbjct: 202 SEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239 Score = 33.9 bits (76), Expect = 0.30 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%) Query: 139 CPVAQS-AMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 CP ++S VC SD +Y S+C ++ ACS+G L G C Sbjct: 274 CPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316 Score = 33.1 bits (74), Expect = 0.51 Identities = 26/100 (26%), Positives = 31/100 (31%), Gaps = 25/100 (25%) Query: 81 PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140 P K+ C V C P K C CV N+ W GP Sbjct: 90 PCKETCENVDCGPGKKCRMNKKNKPRCVCAPDC------SNIT---WKGP---------- 130 Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 VCG DG +Y ++C L C L G C Sbjct: 131 ------VCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164 >gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] Length = 344 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 23/98 (23%) Query: 83 KDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVA 142 K C V C CV A CV+ + P P + Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPE-----------------------PAS 201 Query: 143 QSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 +CG+DG +Y+S C L C G+S+ +G C Sbjct: 202 SEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239 Score = 35.4 bits (80), Expect = 0.10 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 139 CPVAQS-AMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAE 194 CP ++S VC SD +Y S+C ++ ACS+G L G C + E + + E Sbjct: 274 CPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDE 330 Score = 33.1 bits (74), Expect = 0.51 Identities = 26/100 (26%), Positives = 31/100 (31%), Gaps = 25/100 (25%) Query: 81 PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140 P K+ C V C P K C CV N+ W GP Sbjct: 90 PCKETCENVDCGPGKKCRMNKKNKPRCVCAPDC------SNIT---WKGP---------- 130 Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 VCG DG +Y ++C L C L G C Sbjct: 131 ------VCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164 >gi|28212222 WFIKKN2 protein [Homo sapiens] Length = 576 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/150 (24%), Positives = 56/150 (37%), Gaps = 24/150 (16%) Query: 70 NPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKH--- 126 NPN D ++ +C ++ C T CV+ +++ + KKG V Sbjct: 51 NPNLWVDAQSTCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEAT 110 Query: 127 ---------------WVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKS 171 W G + KCK + + C SDG +Y ++C ++ ACS G + Sbjct: 111 CDHFMCLQQGSECDIWDGQP-VCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGIT 169 Query: 172 LATLC-----DGPCPCLPEPEPPKHKAERS 196 LA + P P PE H S Sbjct: 170 LAVVTCRYHFTWPNTSPPPPETTMHPTTAS 199 >gi|55925576 insulin-like growth factor binding protein 2, 36kDa [Homo sapiens] Length = 328 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 18/88 (20%) Query: 308 PGGLPCQNEMNRI-QKLSKGK---------SLLGAFIPRCNEEGYYKATQC----HGSTG 353 P PCQ E++++ +++S + L IP C++ G Y QC +G G Sbjct: 225 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG 284 Query: 354 QCWCVDKYGNELAGSRKQGAVSCEEEQE 381 +CWCV N G QGA + + E Sbjct: 285 ECWCV----NPNTGKLIQGAPTIRGDPE 308 >gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] Length = 263 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 129 GPSNLVKCK--PCPVAQSA--MVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLP 184 G ++ V C+ PCPV S +CG++ +Y S C + C G+S+ G C P Sbjct: 188 GSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTP 247 Query: 185 EPEPPKHKAE 194 E P AE Sbjct: 248 EEPPGGESAE 257 Score = 34.3 bits (77), Expect = 0.23 Identities = 25/102 (24%), Positives = 34/102 (33%), Gaps = 30/102 (29%) Query: 81 PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKP-- 138 P KD C V+C P K C +G +C P Sbjct: 94 PCKDSCDGVECGPGKAC----------------------------RMLGGRPRCECAPDC 125 Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180 + VCGSDG +Y +C+L C L+ + G C Sbjct: 126 SGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRC 167 >gi|5901956 follistatin-like 1 precursor [Homo sapiens] Length = 308 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 135 KCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAE 194 +CKP VCGS+G +Y + C+L AC TG + DG C E + A Sbjct: 57 QCKP----HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC---KEKKSVSPSAS 109 Query: 195 RSACTDKELRNLASRLKDWFGA 216 C L R+ W A Sbjct: 110 PVVCYQSNRDELRRRIIQWLEA 131 >gi|56090548 insulin-like growth factor binding protein-like 1 [Homo sapiens] Length = 278 Score = 39.7 bits (91), Expect = 0.005 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 4/50 (8%) Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKS----LATLCDGPCPCLP 184 C AQ VCGSDG SY S C L A T ++ L DGPC P Sbjct: 106 CVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAP 155 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,990,866 Number of Sequences: 37866 Number of extensions: 1007839 Number of successful extensions: 5724 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 78 Number of HSP's that attempted gapping in prelim test: 5171 Number of HSP's gapped (non-prelim): 411 length of query: 439 length of database: 18,247,518 effective HSP length: 105 effective length of query: 334 effective length of database: 14,271,588 effective search space: 4766710392 effective search space used: 4766710392 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.