Guide to the Human Genome
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Search of human proteins with 4759164

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo...   945   0.0  
gi|93141003 testican 3 isoform 1 [Homo sapiens]                       484   e-137
gi|93141001 testican 3 isoform 2 [Homo sapiens]                       479   e-135
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo...   375   e-104
gi|115298674 nidogen 1 precursor [Homo sapiens]                        64   4e-10
gi|68448544 CD74 antigen isoform a [Homo sapiens]                      61   2e-09
gi|62243068 insulin-like growth factor binding protein 3 isoform...    55   1e-07
gi|62243248 insulin-like growth factor binding protein 3 isoform...    55   1e-07
gi|144953895 nidogen 2 precursor [Homo sapiens]                        54   4e-07
gi|55770862 thyroglobulin [Homo sapiens]                               52   8e-07
gi|11321593 insulin-like growth factor binding protein 6 [Homo s...    52   1e-06
gi|190194423 SPARC-like 1 [Homo sapiens]                               52   1e-06
gi|190341024 SPARC-like 1 [Homo sapiens]                               52   1e-06
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]     52   1e-06
gi|10834982 insulin-like growth factor binding protein 5 [Homo s...    51   2e-06
gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]      51   2e-06
gi|78190498 secreted modular calcium-binding protein 1 isoform 1...    50   3e-06
gi|11545873 secreted modular calcium-binding protein 1 isoform 2...    50   3e-06
gi|54873613 agrin [Homo sapiens]                                       47   3e-05
gi|197313714 sparc/osteonectin, cwcv and kazal-like domains prot...    46   8e-05
gi|4504615 insulin-like growth factor binding protein 1 precurso...    45   2e-04
gi|62243290 insulin-like growth factor binding protein 4 precurs...    44   4e-04
gi|218505670 epithelial cell adhesion molecule precursor [Homo s...    43   6e-04
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]         42   0.001
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]         42   0.001
gi|28212222 WFIKKN2 protein [Homo sapiens]                             42   0.001
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...    42   0.001
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]    41   0.002
gi|5901956 follistatin-like 1 precursor [Homo sapiens]                 40   0.003
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    40   0.005

>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan 1 precursor [Homo sapiens]
          Length = 439

 Score =  945 bits (2442), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF 60
           MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF
Sbjct: 1   MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRF 60

Query: 61  RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120
           RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG
Sbjct: 61  RDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120

Query: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC
Sbjct: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180

Query: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS 240
           PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS
Sbjct: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTS 240

Query: 241 ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE 300
           ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE
Sbjct: 241 ILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNE 300

Query: 301 WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK 360
           WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK
Sbjct: 301 WCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDK 360

Query: 361 YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV 420
           YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV
Sbjct: 361 YGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAV 420

Query: 421 TEDDEDEDDDKEDEVGYIW 439
           TEDDEDEDDDKEDEVGYIW
Sbjct: 421 TEDDEDEDDDKEDEVGYIW 439


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score =  484 bits (1247), Expect = e-137
 Identities = 231/430 (53%), Positives = 288/430 (66%), Gaps = 13/430 (3%)

Query: 5   AVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDK-YWNRFRDD 63
           AVL   AAAWC   + +    A AGG     GNFLD+ QWL+T+SQYD++   WN+FRDD
Sbjct: 6   AVLCVCAAAWCSQSLAAAAAVAAAGGRSDG-GNFLDDKQWLTTISQYDKEVGQWNKFRDD 64

Query: 64  DYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVA 123
           DYFR W+P KPFDQALDP+KDPCLK+KCS HKVC+ QD QTA+C+S + L  R K+  V 
Sbjct: 65  DYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEAGVD 124

Query: 124 QKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCL 183
            + W GP  L  CK CPV   + VCGSDGH+Y+ +CKLE+ AC  GK ++  C+G CPC 
Sbjct: 125 HRQWRGPI-LSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCP 183

Query: 184 PEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKP-TSSNTAQGRFDTSIL 242
            +      +  + AC+D E R +A+RL+DWF ALHE  ++  K  T     + RFDTSIL
Sbjct: 184 SDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSIL 243

Query: 243 PICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWC 302
           PICKDSLGWMFN+LD NYDLLLD SE+ +IYLDK E C K  FNSCD++KD  +SNNEWC
Sbjct: 244 PICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWC 303

Query: 303 YCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYG 362
           YCFQ+    PCQ E++ IQK    K LLG +IP C+E+GYYK TQCHGS GQCWCVD+YG
Sbjct: 304 YCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYG 363

Query: 363 NELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTE 422
           NE+ GSR  G   C  + E SGDF SG      DD + E ++   + E         + +
Sbjct: 364 NEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE---------IED 414

Query: 423 DDEDEDDDKE 432
           DDEDE DD +
Sbjct: 415 DDEDEGDDDD 424


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score =  479 bits (1233), Expect = e-135
 Identities = 231/433 (53%), Positives = 288/433 (66%), Gaps = 16/433 (3%)

Query: 5   AVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDK-YWNRFRD- 62
           AVL   AAAWC   + +    A AGG     GNFLD+ QWL+T+SQYD++   WN+FRD 
Sbjct: 6   AVLCVCAAAWCSQSLAAAAAVAAAGGRSDG-GNFLDDKQWLTTISQYDKEVGQWNKFRDE 64

Query: 63  --DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKG 120
             DDYFR W+P KPFDQALDP+KDPCLK+KCS HKVC+ QD QTA+C+S + L  R K+ 
Sbjct: 65  VEDDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEA 124

Query: 121 NVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
            V  + W GP  L  CK CPV   + VCGSDGH+Y+ +CKLE+ AC  GK ++  C+G C
Sbjct: 125 GVDHRQWRGPI-LSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHC 183

Query: 181 PCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKP-TSSNTAQGRFDT 239
           PC  +      +  + AC+D E R +A+RL+DWF ALHE  ++  K  T     + RFDT
Sbjct: 184 PCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDT 243

Query: 240 SILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNN 299
           SILPICKDSLGWMFN+LD NYDLLLD SE+ +IYLDK E C K  FNSCD++KD  +SNN
Sbjct: 244 SILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNN 303

Query: 300 EWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVD 359
           EWCYCFQ+    PCQ E++ IQK    K LLG +IP C+E+GYYK TQCHGS GQCWCVD
Sbjct: 304 EWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVD 363

Query: 360 KYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRA 419
           +YGNE+ GSR  G   C  + E SGDF SG      DD + E ++   + E         
Sbjct: 364 RYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE--------- 414

Query: 420 VTEDDEDEDDDKE 432
           + +DDEDE DD +
Sbjct: 415 IEDDDEDEGDDDD 427


>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan (testican) 2 isoform 2 [Homo sapiens]
          Length = 424

 Score =  375 bits (963), Expect = e-104
 Identities = 202/445 (45%), Positives = 269/445 (60%), Gaps = 42/445 (9%)

Query: 4   IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62
           + +LAAAA A           DA     G   GNF++++QWLS++SQY  + K+WNRFRD
Sbjct: 13  LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63

Query: 63  ---DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKK 119
              DDY ++W  N+  D+ALD +KDPC KVKCS HKVC+ Q YQ A+C+SRK L  R K+
Sbjct: 64  EVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQ 123

Query: 120 GNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGP 179
             V      G  + + CKPC +AQ A VCGSDGH+Y+S CKLE  AC + K LA  C+GP
Sbjct: 124 PTVKLH---GNKDSI-CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGP 179

Query: 180 CPCLPEPEPPKHK-AERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFD 238
           CPC  E         +   CT ++L +L  RL+DWF  LHE++ +    +S        D
Sbjct: 180 CPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLD 239

Query: 239 TSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSN 298
            S+   CKDS+GWMF+KLD + DL LD +E+ AI LDKYE CI+P FNSCD++KDG++S 
Sbjct: 240 KSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVST 299

Query: 299 NEWCYCF--QKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCW 356
            EWC+CF  +KP   PC  E+ RIQ     K   G FIP C+E+GYY+  QC  S+G CW
Sbjct: 300 AEWCFCFWREKP---PCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCW 356

Query: 357 CVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVH 416
           CVD+ G EL G+R  G+  C++    SGDFGSG              +G +D+E K    
Sbjct: 357 CVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSG--------------VGWEDEEEK---E 399

Query: 417 TRAVTEDDEDEDDD--KEDEVGYIW 439
           T    E+ E+E+ +  + D+ GYIW
Sbjct: 400 TEEAGEEAEEEEGEAGEADDGGYIW 424


>gi|115298674 nidogen 1 precursor [Homo sapiens]
          Length = 1247

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 28/95 (29%)

Query: 303 YCFQKPGGLPCQ--------------NEMNRIQKLSKGKSLLGA--------------FI 334
           +C+  PG   CQ               E+ + +   + + +LGA              F+
Sbjct: 816 FCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFV 875

Query: 335 PRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSR 369
           P C+  G+Y  TQCHGSTG CWCVD+ G E+ G+R
Sbjct: 876 PECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR 910


>gi|68448544 CD74 antigen isoform a [Homo sapiens]
          Length = 296

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 19/107 (17%)

Query: 306 QKPGGLP------CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVD 359
           QKP   P      CQ E++ I  +  G     +F P+C+E G Y   QC+GS G CWCV 
Sbjct: 200 QKPTDAPPKVLTKCQEEVSHIPAVHPG-----SFRPKCDENGNYLPLQCYGSIGYCWCVF 254

Query: 360 KYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGP 406
             G E+  +R +G  +C E  E   D  SG  V        +++LGP
Sbjct: 255 PNGTEVPNTRSRGHHNCSESLELE-DPSSGLGVT-------KQDLGP 293


>gi|62243068 insulin-like growth factor binding protein 3 isoform b
           precursor [Homo sapiens]
          Length = 291

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%)

Query: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
           PC+ EM       K  ++L   G  IP C+++G+YK  QC  S G+    CWCVDKYG  
Sbjct: 212 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271

Query: 365 LAGSRKQG 372
           L G   +G
Sbjct: 272 LPGYTTKG 279


>gi|62243248 insulin-like growth factor binding protein 3 isoform a
           precursor [Homo sapiens]
          Length = 297

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%)

Query: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
           PC+ EM       K  ++L   G  IP C+++G+YK  QC  S G+    CWCVDKYG  
Sbjct: 218 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277

Query: 365 LAGSRKQG 372
           L G   +G
Sbjct: 278 LPGYTTKG 285


>gi|144953895 nidogen 2 precursor [Homo sapiens]
          Length = 1375

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 20/36 (55%), Positives = 28/36 (77%)

Query: 334 IPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSR 369
           IP+C+E+G +   QCHGSTG CWCVD  G+E+ G++
Sbjct: 960 IPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQ 995



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 18/39 (46%), Positives = 28/39 (71%)

Query: 333  FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371
            ++P+C++ G++   QCHG +  CWCVDK G E+ G+R Q
Sbjct: 1039 YVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQ 1077


>gi|55770862 thyroglobulin [Homo sapiens]
          Length = 2768

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query: 312 PCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371
           P + E+ R    S G      ++P C   G Y+A QC  + G CWCVD  G E+ G+R+Q
Sbjct: 298 PTKCEVERFTATSFGHP----YVPSCRRNGDYQAVQCQ-TEGPCWCVDAQGKEMHGTRQQ 352

Query: 372 G-AVSCEEEQETSGD 385
           G   SC E Q  + +
Sbjct: 353 GEPPSCAEGQSCASE 367



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 7/53 (13%)

Query: 333 FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGA-----VSCEEEQ 380
           F+P C  EG Y+  QC   +G+CWCV+ +G EL GSR +G        CE+++
Sbjct: 616 FVPSCTTEGSYEDVQCF--SGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQR 666



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 281  IKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLL---GAFIPRC 337
            + PLF   ++F +  L  +++         L            S G S L   G ++P+C
Sbjct: 972  LPPLFPPREAFAEQFLRGSDYAIRLAAQSTLSFYQRRRFSPDDSAGASALLRSGPYMPQC 1031

Query: 338  NEEGYYKATQCHGSTGQCWCVDKYGNELAGS 368
            +  G ++  QCH  TG CWCVD+ G  + GS
Sbjct: 1032 DAFGSWEPVQCHAGTGHCWCVDEKGGFIPGS 1062



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 333 FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQG-AVSC 376
           ++P+C E+G ++  QC      CWCV   G+E+ GSR+ G  V+C
Sbjct: 48  YVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVAC 92



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 21/60 (35%), Positives = 31/60 (51%)

Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQG 372
           CQ +  +I       S   +++P+C + G Y   QC     QCWCVD  G E+ G+R+ G
Sbjct: 96  CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLG 155



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 10/68 (14%)

Query: 309 GGLP-----CQNEMNRIQKLSKGKSLLGA--FIPRCNEEGYYKATQCHGSTGQCWCVDKY 361
           GG P     C+ +  R+Q L  G    G+  F+P C  EG++   QC  S  +C+CVD  
Sbjct: 653 GGQPRCPTDCEKQRARMQSLM-GSQPAGSTLFVPACTSEGHFLPVQCFNS--ECYCVDAE 709

Query: 362 GNELAGSR 369
           G  + G+R
Sbjct: 710 GQAIPGTR 717



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 313  CQNEMNRIQKLSKGKSLLGAFIPRCN-EEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQ 371
            C +  N ++     + +   ++P C  E+G +   QC  + G CWCV   G E+ G+R  
Sbjct: 1145 CPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVT 1204

Query: 372  GA-VSCE 377
            G   +CE
Sbjct: 1205 GGQPACE 1211



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 6/36 (16%)

Query: 349 HGSTGQCWCVDKYGNELAGSRKQGAV------SCEE 378
           H     CWCVD+ G EL G R + +       SCEE
Sbjct: 892 HFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEE 927



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 25/81 (30%)

Query: 299 NEWCYCFQKPGGL----------------PCQNE-----MNRIQKLSKGKSLL----GAF 333
           N  CYC    G                  PCQ +     +  +Q L    S+L      +
Sbjct: 700 NSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTY 759

Query: 334 IPRCNEEGYYKATQCHGSTGQ 354
           IP+C+ +G ++  QC+G   Q
Sbjct: 760 IPQCSTDGQWRQVQCNGPPEQ 780



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 336  RCNEEGYYKATQCHGSTGQCWCVDKYGNEL 365
            +C++ G Y+A+Q    +G+ +CVD  G  L
Sbjct: 1522 QCDQNGQYRASQKDRGSGKAFCVDGEGRRL 1551


>gi|11321593 insulin-like growth factor binding protein 6 [Homo
           sapiens]
          Length = 240

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 8/73 (10%)

Query: 312 PCQNEMNRIQKLSKGKSLLGA---FIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
           PC+  ++ + +  + +   GA   ++P C+  G+Y+  QC  S GQ    CWCVD+ G  
Sbjct: 162 PCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKS 221

Query: 365 LAGSRK-QGAVSC 376
           L GS    G+ SC
Sbjct: 222 LPGSPDGNGSSSC 234


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 58/225 (25%), Positives = 84/225 (37%), Gaps = 49/225 (21%)

Query: 118 KKGNVAQKHWVGPSNLVKCKP--CPVAQSA-MVCGSDGHSYTSKCKLEFHAC-----STG 169
           K+G++ +    G  + V   P  CP  +    VCG+D  +Y S C L    C       G
Sbjct: 439 KRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKG 498

Query: 170 KSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWF--------------- 214
             L     G C  +P             CTD E+     R++DW                
Sbjct: 499 HQLQLDYFGACKSIP------------TCTDFEVIQFPLRMRDWLKNILMQLYEANSEHA 546

Query: 215 GALHE-DANRVIKPTSSNTAQGRFDTSILPICKD----------SLGWMFNKLDMN-YDL 262
           G L+E   N+V K           D  I  + +D           + W F++LD +  D 
Sbjct: 547 GYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDR 606

Query: 263 LLDPSEINAI--YLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCF 305
           +L  SE+  +   L   E CI   F  CD  KD  ++  EW +CF
Sbjct: 607 VLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCF 651


>gi|190341024 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 58/225 (25%), Positives = 84/225 (37%), Gaps = 49/225 (21%)

Query: 118 KKGNVAQKHWVGPSNLVKCKP--CPVAQSA-MVCGSDGHSYTSKCKLEFHAC-----STG 169
           K+G++ +    G  + V   P  CP  +    VCG+D  +Y S C L    C       G
Sbjct: 439 KRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKG 498

Query: 170 KSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWF--------------- 214
             L     G C  +P             CTD E+     R++DW                
Sbjct: 499 HQLQLDYFGACKSIP------------TCTDFEVIQFPLRMRDWLKNILMQLYEANSEHA 546

Query: 215 GALHE-DANRVIKPTSSNTAQGRFDTSILPICKD----------SLGWMFNKLDMN-YDL 262
           G L+E   N+V K           D  I  + +D           + W F++LD +  D 
Sbjct: 547 GYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDR 606

Query: 263 LLDPSEINAI--YLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCF 305
           +L  SE+  +   L   E CI   F  CD  KD  ++  EW +CF
Sbjct: 607 VLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCF 651


>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
          Length = 457

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGS 368
           C  E    Q+ ++ K     FIP CN++G Y   QCH  TG CWCV   G  ++G+
Sbjct: 90  CVAERKYTQEQAR-KEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGT 144



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 19/46 (41%), Positives = 21/46 (45%)

Query: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCV 358
           C  E     + +K        IP C   G YK  QCH STG CWCV
Sbjct: 227 CDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCV 272


>gi|10834982 insulin-like growth factor binding protein 5 [Homo
           sapiens]
          Length = 272

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 7/63 (11%)

Query: 312 PCQNEMNR-IQKLSKGKSLL--GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
           PC+  M   +Q+L     ++    ++P C+ +G+YK  QC  S G+    CWCVDKYG +
Sbjct: 191 PCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMK 250

Query: 365 LAG 367
           L G
Sbjct: 251 LPG 253


>gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]
          Length = 303

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/257 (22%), Positives = 88/257 (34%), Gaps = 67/257 (26%)

Query: 82  SKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPV 141
           +++PC    C   KVC   +  T +CV +                   P++     P P+
Sbjct: 68  AENPCQNHHCKHGKVCELDENNTPMCVCQ------------------DPTSC----PAPI 105

Query: 142 AQSAMVCGSDGHSYTSKC-----KLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERS 196
            +   VC +D  ++ S C     K        G  L     GPC  +P            
Sbjct: 106 GEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIP------------ 153

Query: 197 ACTDKELRNLASRLKDWFGAL-------HEDAN--------RVIKPTSSNTAQGRFDTSI 241
            C D EL     R++DW   +        ED N        RV K   +       D  +
Sbjct: 154 PCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPV 213

Query: 242 LPICKD----------SLGWMFNKLDMN-YDLLLDPSEINAIY--LDKYEPCIKPLFNSC 288
             + +D           + W F +LD +  D  L  +E+  +   L   E C    F +C
Sbjct: 214 ELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETC 273

Query: 289 DSFKDGKLSNNEWCYCF 305
           D   D  ++ +EW  CF
Sbjct: 274 DLDNDKYIALDEWAGCF 290


>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 435

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 317 MNRIQKLSKGKSLLGA-FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVS 375
           + R Q L + K    A F+P C E+G +   QCH  TG CWCV   G  ++GS  Q    
Sbjct: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156

Query: 376 CEEEQETSGDFGSGGS 391
                 T      G S
Sbjct: 157 VCSGSVTDKPLSQGNS 172



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 77/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%)

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSAC 198
           C   Q   +C SDG SY S C+ +   C    +L  +  G C    +    K + ER+  
Sbjct: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCK---DAGQSKCRLERAQA 102

Query: 199 TDKELRNLASRLKDWFGALHEDANRVI-----------------KPTSSNTAQGRFDTSI 241
            ++  +   +      G   ED +                    KP S ++ Q +     
Sbjct: 103 LEQAKKPQEAVFVPECG---EDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK----- 154

Query: 242 LPICKDSL-------GWMFNKLD-------MNYDLLLDPSEINAIYLDKYEPCIKPLFNS 287
            P+C  S+       G    K D       M    + D  EI A  L      IK L   
Sbjct: 155 TPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTL-----WIKHLVIK 209

Query: 288 CDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQ 347
                +  + N+E  Y         C  E     + ++     G  IP C   G YK  Q
Sbjct: 210 DSKLNNTNIRNSEKVYS--------CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQ 261

Query: 348 CHGSTGQCWCV-DKYGNELAG-SRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELG 405
           CH STG CWCV    G  L G S +    SCE +        +       DD   +REL 
Sbjct: 262 CHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD--------ARAKTTEADDPFKDREL- 312

Query: 406 PKDKEGK 412
           P   EGK
Sbjct: 313 PGCPEGK 319


>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 434

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 317 MNRIQKLSKGKSLLGA-FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVS 375
           + R Q L + K    A F+P C E+G +   QCH  TG CWCV   G  ++GS  Q    
Sbjct: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156

Query: 376 CEEEQETSGDFGSGGS 391
                 T      G S
Sbjct: 157 VCSGSVTDKPLSQGNS 172



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 77/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%)

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSAC 198
           C   Q   +C SDG SY S C+ +   C    +L  +  G C    +    K + ER+  
Sbjct: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCK---DAGQSKCRLERAQA 102

Query: 199 TDKELRNLASRLKDWFGALHEDANRVI-----------------KPTSSNTAQGRFDTSI 241
            ++  +   +      G   ED +                    KP S ++ Q +     
Sbjct: 103 LEQAKKPQEAVFVPECG---EDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK----- 154

Query: 242 LPICKDSL-------GWMFNKLD-------MNYDLLLDPSEINAIYLDKYEPCIKPLFNS 287
            P+C  S+       G    K D       M    + D  EI A  L      IK L   
Sbjct: 155 TPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTL-----WIKHLVIK 209

Query: 288 CDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQ 347
                +  + N+E  Y         C  E     + ++     G  IP C   G YK  Q
Sbjct: 210 DSKLNNTNIRNSEKVYS--------CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQ 261

Query: 348 CHGSTGQCWCV-DKYGNELAG-SRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELG 405
           CH STG CWCV    G  L G S +    SCE +        +       DD   +REL 
Sbjct: 262 CHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD--------ARAKTTEADDPFKDREL- 312

Query: 406 PKDKEGK 412
           P   EGK
Sbjct: 313 PGCPEGK 319


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 139 CP---VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           CP   VA +  VCGSDGH+Y S+C L  HAC+   SL     GPC
Sbjct: 555 CPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPC 599



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/110 (32%), Positives = 46/110 (41%), Gaps = 31/110 (28%)

Query: 82  SKDPCLKVKCSPHKVCV-TQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140
           S+DPC  V CS    C  + D  TA C     L P   +G                    
Sbjct: 244 SRDPCSNVTCSFGSTCARSADGLTASC-----LCPATCRG-------------------- 278

Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC-PC---LPEP 186
            A    VCGSDG  Y  +C+L   AC+  +++    DGPC PC   LP+P
Sbjct: 279 -APEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDP 327



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 120 GNVAQKHWVGP---SNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLC 176
           G V + +  GP   S + K  PCP +  A VCGSD  +Y+++C+L+   CS  + +  L 
Sbjct: 180 GAVCEPNAEGPGRASCVCKKSPCP-SVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLS 238

Query: 177 DGPC----PC 182
            GPC    PC
Sbjct: 239 RGPCGSRDPC 248



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 18/42 (42%), Positives = 26/42 (61%)

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           CP A +  VCGSDG +Y ++C+L+  AC  G  ++    GPC
Sbjct: 928 CPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPC 969



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 28/101 (27%)

Query: 80  DPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPC 139
           D +  PCL V+C+    C  ++ Q A                             +C   
Sbjct: 462 DQAPSPCLGVQCAFGATCAVKNGQAAC----------------------------ECLQA 493

Query: 140 PVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
             +    VCGSDG +Y S C+LE  AC+ G+ +     GPC
Sbjct: 494 CSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPC 534



 Score = 35.8 bits (81), Expect = 0.079
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           C     + VCGSDG +Y+++C+L+   C + + L     G C
Sbjct: 709 CQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 17/45 (37%), Positives = 20/45 (44%)

Query: 136 CKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           C  C       VCGSDG +Y S C+L   AC     +     GPC
Sbjct: 620 CPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPC 664



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 130 PSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPE-PEP 188
           P  L++ + CP A+ A VCG DG +Y + C +     + G  L  +  G C    + PEP
Sbjct: 340 PEMLLRPESCP-ARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEP 398

Query: 189 PKHKA 193
            +  A
Sbjct: 399 CRFNA 403



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 13/40 (32%), Positives = 19/40 (47%)

Query: 147 VCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEP 186
           VC  DG +Y S C  +   C   +++ +   GPC   P P
Sbjct: 428 VCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSP 467


>gi|197313714 sparc/osteonectin, cwcv and kazal-like domains
          proteoglycan (testican) 2 isoform 1 [Homo sapiens]
          Length = 77

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 26/60 (43%), Positives = 36/60 (60%), Gaps = 10/60 (16%)

Query: 4  IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62
          + +LAAAA A           DA     G   GNF++++QWLS++SQY  + K+WNRFRD
Sbjct: 13 LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63


>gi|4504615 insulin-like growth factor binding protein 1 precursor
           [Homo sapiens]
          Length = 259

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 12/78 (15%)

Query: 312 PCQNEMNRI-QKLSKGKSLLGA-----FIPRCNEEGYYKATQCH----GSTGQCWCVDKY 361
           PC+ E+ R+ + L+K +   G      ++P CN+ G+Y + QC     G  G CWCV  +
Sbjct: 175 PCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPW 234

Query: 362 -GNELAGSRK-QGAVSCE 377
            G  + GS + +G  +C+
Sbjct: 235 NGKRIPGSPEIRGDPNCQ 252


>gi|62243290 insulin-like growth factor binding protein 4 precursor
           [Homo sapiens]
          Length = 258

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 12/78 (15%)

Query: 313 CQNEMNR-IQKLSKGKS-----LLGAFIPRCNEEGYYKATQCH----GSTGQCWCVD-KY 361
           CQ+E++R +++L+  +S     L    IP C+  G +   QCH    G  G+CWCVD K 
Sbjct: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233

Query: 362 GNELAGS-RKQGAVSCEE 378
           G +L G    +G + C +
Sbjct: 234 GVKLPGGLEPKGELDCHQ 251


>gi|218505670 epithelial cell adhesion molecule precursor [Homo
           sapiens]
          Length = 314

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 331 GAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQET 382
           G + P C+E G +KA QC+G T  CWCV+  G  +  + K   ++C E   T
Sbjct: 93  GLYDPDCDESGLFKAKQCNG-TSMCWCVNTAG--VRRTDKDTEITCSERVRT 141


>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
          Length = 317

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 23/98 (23%)

Query: 83  KDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVA 142
           K  C  V C     CV      A CV+   + P                        P +
Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPE-----------------------PAS 201

Query: 143 QSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
               +CG+DG +Y+S C L    C  G+S+    +G C
Sbjct: 202 SEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 139 CPVAQS-AMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
           CP ++S   VC SD  +Y S+C ++  ACS+G  L     G C
Sbjct: 274 CPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 26/100 (26%), Positives = 31/100 (31%), Gaps = 25/100 (25%)

Query: 81  PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140
           P K+ C  V C P K C         CV            N+    W GP          
Sbjct: 90  PCKETCENVDCGPGKKCRMNKKNKPRCVCAPDC------SNIT---WKGP---------- 130

Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
                 VCG DG +Y ++C L    C     L     G C
Sbjct: 131 ------VCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164


>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 23/98 (23%)

Query: 83  KDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVA 142
           K  C  V C     CV      A CV+   + P                        P +
Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPE-----------------------PAS 201

Query: 143 QSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
               +CG+DG +Y+S C L    C  G+S+    +G C
Sbjct: 202 SEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 139 CPVAQS-AMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAE 194
           CP ++S   VC SD  +Y S+C ++  ACS+G  L     G C  + E    + + E
Sbjct: 274 CPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDE 330



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 26/100 (26%), Positives = 31/100 (31%), Gaps = 25/100 (25%)

Query: 81  PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCP 140
           P K+ C  V C P K C         CV            N+    W GP          
Sbjct: 90  PCKETCENVDCGPGKKCRMNKKNKPRCVCAPDC------SNIT---WKGP---------- 130

Query: 141 VAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
                 VCG DG +Y ++C L    C     L     G C
Sbjct: 131 ------VCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164


>gi|28212222 WFIKKN2 protein [Homo sapiens]
          Length = 576

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 36/150 (24%), Positives = 56/150 (37%), Gaps = 24/150 (16%)

Query: 70  NPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKH--- 126
           NPN   D      ++     +C  ++ C      T  CV+ +++  + KKG V       
Sbjct: 51  NPNLWVDAQSTCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEAT 110

Query: 127 ---------------WVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKS 171
                          W G   + KCK     + +  C SDG +Y ++C ++  ACS G +
Sbjct: 111 CDHFMCLQQGSECDIWDGQP-VCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGIT 169

Query: 172 LATLC-----DGPCPCLPEPEPPKHKAERS 196
           LA +        P    P PE   H    S
Sbjct: 170 LAVVTCRYHFTWPNTSPPPPETTMHPTTAS 199


>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 18/88 (20%)

Query: 308 PGGLPCQNEMNRI-QKLSKGK---------SLLGAFIPRCNEEGYYKATQC----HGSTG 353
           P   PCQ E++++ +++S  +          L    IP C++ G Y   QC    +G  G
Sbjct: 225 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG 284

Query: 354 QCWCVDKYGNELAGSRKQGAVSCEEEQE 381
           +CWCV    N   G   QGA +   + E
Sbjct: 285 ECWCV----NPNTGKLIQGAPTIRGDPE 308


>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
          Length = 263

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 129 GPSNLVKCK--PCPVAQSA--MVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLP 184
           G ++ V C+  PCPV  S    +CG++  +Y S C +    C  G+S+     G C   P
Sbjct: 188 GSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTP 247

Query: 185 EPEPPKHKAE 194
           E  P    AE
Sbjct: 248 EEPPGGESAE 257



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 25/102 (24%), Positives = 34/102 (33%), Gaps = 30/102 (29%)

Query: 81  PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKP-- 138
           P KD C  V+C P K C                              +G     +C P  
Sbjct: 94  PCKDSCDGVECGPGKAC----------------------------RMLGGRPRCECAPDC 125

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
             +     VCGSDG +Y  +C+L    C     L+ +  G C
Sbjct: 126 SGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRC 167


>gi|5901956 follistatin-like 1 precursor [Homo sapiens]
          Length = 308

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%)

Query: 135 KCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAE 194
           +CKP        VCGS+G +Y + C+L   AC TG  +    DG C    E +     A 
Sbjct: 57  QCKP----HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC---KEKKSVSPSAS 109

Query: 195 RSACTDKELRNLASRLKDWFGA 216
              C       L  R+  W  A
Sbjct: 110 PVVCYQSNRDELRRRIIQWLEA 131


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKS----LATLCDGPCPCLP 184
           C  AQ   VCGSDG SY S C L   A  T ++    L    DGPC   P
Sbjct: 106 CVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAP 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,990,866
Number of Sequences: 37866
Number of extensions: 1007839
Number of successful extensions: 5724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 5171
Number of HSP's gapped (non-prelim): 411
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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