BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens] (1152 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 2253 0.0 gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 2124 0.0 gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 956 0.0 gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 723 0.0 gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 213 8e-55 gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 207 5e-53 gi|47519699 microtubule-associated protein 4 isoform 3 [Homo sap... 195 2e-49 gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 193 7e-49 gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 190 8e-48 gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 189 2e-47 gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 185 2e-46 gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 184 3e-46 gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 147 6e-35 gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 140 7e-33 gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 128 4e-29 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 115 2e-25 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 115 2e-25 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 115 2e-25 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 115 2e-25 gi|110349719 titin isoform N2-A [Homo sapiens] 96 2e-19 gi|91982772 mucin 17 [Homo sapiens] 88 5e-17 gi|38261962 activating transcription factor 7 interacting protei... 87 1e-16 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 83 2e-15 gi|163965366 nascent polypeptide-associated complex alpha subuni... 80 9e-15 gi|116284392 mucin 2 precursor [Homo sapiens] 77 9e-14 gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 76 2e-13 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 74 6e-13 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 70 9e-12 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 70 1e-11 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 70 1e-11 >gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens] Length = 1152 Score = 2253 bits (5839), Expect = 0.0 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%) Query: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS Sbjct: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 Query: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP Sbjct: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120 Query: 121 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP Sbjct: 121 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180 Query: 181 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE Sbjct: 181 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240 Query: 241 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM Sbjct: 241 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300 Query: 301 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI Sbjct: 301 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360 Query: 361 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ Sbjct: 361 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420 Query: 421 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ Sbjct: 421 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480 Query: 481 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM Sbjct: 481 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540 Query: 541 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG Sbjct: 541 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE Sbjct: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660 Query: 661 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ Sbjct: 661 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720 Query: 721 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK Sbjct: 721 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780 Query: 781 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE Sbjct: 781 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840 Query: 841 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST Sbjct: 841 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900 Query: 901 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT Sbjct: 901 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960 Query: 961 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG Sbjct: 961 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020 Query: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL Sbjct: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080 Query: 1081 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1140 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA Sbjct: 1081 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1140 Query: 1141 QTLDSQIQETSI 1152 QTLDSQIQETSI Sbjct: 1141 QTLDSQIQETSI 1152 >gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sapiens] Length = 1135 Score = 2124 bits (5504), Expect = 0.0 Identities = 1088/1089 (99%), Positives = 1088/1089 (99%) Query: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS Sbjct: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 Query: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP Sbjct: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120 Query: 121 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP Sbjct: 121 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180 Query: 181 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE Sbjct: 181 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240 Query: 241 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM Sbjct: 241 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300 Query: 301 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI Sbjct: 301 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360 Query: 361 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ Sbjct: 361 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420 Query: 421 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ Sbjct: 421 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480 Query: 481 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM Sbjct: 481 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540 Query: 541 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG Sbjct: 541 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE Sbjct: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660 Query: 661 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ Sbjct: 661 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720 Query: 721 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK Sbjct: 721 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780 Query: 781 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE Sbjct: 781 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840 Query: 841 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST Sbjct: 841 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900 Query: 901 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT Sbjct: 901 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960 Query: 961 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG Sbjct: 961 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020 Query: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL Sbjct: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080 Query: 1081 PAGGAVKTE 1089 PAGGAVK E Sbjct: 1081 PAGGAVKIE 1089 >gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sapiens] Length = 887 Score = 956 bits (2471), Expect = 0.0 Identities = 509/589 (86%), Positives = 522/589 (88%), Gaps = 23/589 (3%) Query: 580 SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634 S+ EA P + D + T KG+ +D LE+ Q + + S G GKK Sbjct: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358 Query: 635 --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 S AE + L L + Q +++GIARPEEGRPVVSGTGN Sbjct: 359 EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418 Query: 684 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL Sbjct: 419 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478 Query: 744 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS Sbjct: 479 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538 Query: 804 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS Sbjct: 539 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598 Query: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL Sbjct: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658 Query: 924 ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983 ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS Sbjct: 659 ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 718 Query: 984 AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043 AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA Sbjct: 719 AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 778 Query: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 1103 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA Sbjct: 779 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 838 Query: 1104 GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 1152 GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI Sbjct: 839 GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 887 >gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sapiens] Length = 817 Score = 723 bits (1866), Expect = 0.0 Identities = 406/589 (68%), Positives = 434/589 (73%), Gaps = 94/589 (15%) Query: 580 SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634 S+ EA P + D + T KG+ +D LE+ Q + + S G GKK Sbjct: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358 Query: 635 --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 S AE + L L + Q +++GIARPEEGRPVVSGTGN Sbjct: 359 EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418 Query: 684 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL Sbjct: 419 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478 Query: 744 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS Sbjct: 479 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538 Query: 804 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS Sbjct: 539 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598 Query: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL Sbjct: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658 Query: 924 ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983 ATNTSAPDLKNVRSKVGSTENIKHQPGGGR +++ Sbjct: 659 ATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQ-------------------------- 692 Query: 984 AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDI-SKVSSKCGSK 1042 +KKV S + SKCGSK NIKH PGGG+V+I+++K++ K +K GS Sbjct: 693 ------------NKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSL 740 Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPP 1102 N+ H P G GAVKTEGGGSEAPLCPGPP Sbjct: 741 DNVGHLPAG--------------------------------GAVKTEGGGSEAPLCPGPP 768 Query: 1103 AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETS 1151 AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQET+ Sbjct: 769 AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817 >gi|178557734 microtubule-associated protein tau isoform 6 [Homo sapiens] Length = 776 Score = 213 bits (542), Expect = 8e-55 Identities = 170/529 (32%), Positives = 238/529 (44%), Gaps = 86/529 (16%) Query: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632 A +P A P+P+ + T+ SE + GQ A F E Sbjct: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312 Query: 633 KKCSLPAEEDSVLEKL------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT 686 K+ A + L + GE ++ + + P E +P + G ++ Sbjct: 313 KE---QAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVS 369 Query: 687 TPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT---QPTSLPKQPAPTTIGGLNKKPMS 742 P + + K + + AKTST S AKT +P PK P P G + + Sbjct: 370 RVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----GSSDPLIQ 425 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802 +S V PP P S+ S S K + A K A+P + A+ P + + Sbjct: 426 PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP-RGAAPPGQKGQAN 484 Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRP 861 +T+ AKT A T PSS + P ++E G+P + + S P P Sbjct: 485 ATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTP 541 Query: 862 KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921 S S + P+ P+R P + + K P+SAK S Sbjct: 542 GSRSRT------------PSLPTPPTRE-----PKKVAVVRTPPKSPSSAK--------S 576 Query: 922 RLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980 RL T PDLKNV+SK+GSTEN+KHQPGGG Sbjct: 577 RLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG---------------------------- 608 Query: 981 IASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCG 1040 KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCG Sbjct: 609 ----------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCG 658 Query: 1041 SKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 S NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E Sbjct: 659 SLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 707 >gi|82534351 microtubule-associated protein tau isoform 1 [Homo sapiens] Length = 758 Score = 207 bits (527), Expect = 5e-53 Identities = 172/527 (32%), Positives = 224/527 (42%), Gaps = 100/527 (18%) Query: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632 A +P A P+P+ + T+ SE + GQ A F E Sbjct: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312 Query: 633 KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692 K E+ E LG R P E PE P + + P E Sbjct: 313 K------EQAHSEEHLG-RAAFPGAPGE---------GPEARGPSLGEDTKEADLPEPSE 356 Query: 693 LPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP 752 P+ + KP++ K T + A T+ K + P Sbjct: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR-----PCLS 411 Query: 753 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV----- 807 PK P S+ P I PS + A PE +SP K S+ SR+GS + + Sbjct: 412 PKHPTPGSSDPLIQPS--------SPAVCPEPPSSP-KHVSSVTSRTGSSGAKEMKLKGA 462 Query: 808 ---AKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863 K T A G ++ +T +P K P A KT E K +S S P S Sbjct: 463 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 519 Query: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923 T + T T P V TP K P+SAK SRL Sbjct: 520 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 560 Query: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982 T PDLKNV+SK+GSTEN+KHQPGGG Sbjct: 561 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 590 Query: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042 KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS Sbjct: 591 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642 Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E Sbjct: 643 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 689 >gi|47519699 microtubule-associated protein 4 isoform 3 [Homo sapiens] Length = 99 Score = 195 bits (495), Expect = 2e-49 Identities = 97/97 (100%), Positives = 97/97 (100%) Query: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS Sbjct: 1 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60 Query: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT 97 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT Sbjct: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT 97 >gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sapiens] Length = 502 Score = 193 bits (491), Expect = 7e-49 Identities = 132/356 (37%), Positives = 182/356 (51%), Gaps = 69/356 (19%) Query: 748 VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 794 +P +PP PA A ++ PS K K K ++D K+PEKR+S +P+S Sbjct: 133 LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191 Query: 795 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 854 R G + + ++++S+ + + + T P +T + Sbjct: 192 LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-ITPGTP 250 Query: 855 PADLSR-PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913 P+ SR P + T S +T GT +A +VPS K + + P Sbjct: 251 PSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK-------------- 296 Query: 914 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973 S TP+ RL N PDLKNV+SK+GST+NIK+QP GG+ Sbjct: 297 SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNIKYQPKGGQ-------------------- 335 Query: 974 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033 V+I++KK+ +S +QS+CGSKDNIKH GGGNVQI KK+D+S Sbjct: 336 ------------------VRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLS 377 Query: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 V+SKCGS NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN H+P GG VK + Sbjct: 378 HVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 433 >gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sapiens] Length = 559 Score = 190 bits (482), Expect = 8e-48 Identities = 143/420 (34%), Positives = 201/420 (47%), Gaps = 81/420 (19%) Query: 688 PPNKELPPSP--------EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK 739 PP+ PPSP E+ + P+ +K K ++L K PA + G K Sbjct: 134 PPSP--PPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSNSTLSKIPA---LQGSTKS 188 Query: 740 PMSLASGLVPAAPPK---------RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK 790 P S P+ + +P A + + SK + K+PEKR+S + Sbjct: 189 PRY--SSACPSTTKRATFSDSLLIQPTSAGSTDRLPYSKSGNKDGVT--KSPEKRSSLPR 244 Query: 791 PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMT 850 P+S R G + + ++++S+ + + + T P +T Sbjct: 245 PSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-IT 303 Query: 851 AKSVPADLSR-PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPT 909 + P+ SR P + T S +T GT +A +VPS K + + P Sbjct: 304 PGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK---------- 353 Query: 910 SAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKP 969 S TP+ RL N PDLKNV+SK+GST+NIK+QP GG+ Sbjct: 354 ----SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNIKYQPKGGQ---------------- 392 Query: 970 ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKK 1029 V+I++KK+ +S +QS+CGSKDNIKH GGGNVQI KK Sbjct: 393 ----------------------VRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKK 430 Query: 1030 VDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 +D+S V+SKCGS NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN H+P GG VK + Sbjct: 431 IDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 490 >gi|6754638 microtubule-associated protein tau isoform 2 [Homo sapiens] Length = 441 Score = 189 bits (479), Expect = 2e-47 Identities = 131/380 (34%), Positives = 180/380 (47%), Gaps = 68/380 (17%) Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 790 T GL + P+ + P + A + P+ ++DV P+ D AP K+A+ Sbjct: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94 Query: 791 ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847 P A +G T ++ + S T K K +G + K Sbjct: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150 Query: 848 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 899 T + + ++ +T KT T P++G P S + P S Sbjct: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210 Query: 900 TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 949 TP + PT P S + SRL T PDLKNV+SK+GSTEN+KHQP Sbjct: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270 Query: 950 GGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCG 1009 GGG KVQI++KK+ S++QSKCG Sbjct: 271 GGG--------------------------------------KVQIINKKLDLSNVQSKCG 292 Query: 1010 SKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQA 1069 SKDNIKHVPGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+ Sbjct: 293 SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS 352 Query: 1070 KVGSLDNVGHLPAGGAVKTE 1089 K+GSLDN+ H+P GG K E Sbjct: 353 KIGSLDNITHVPGGGNKKIE 372 Score = 33.9 bits (76), Expect = 0.92 Identities = 42/201 (20%), Positives = 69/201 (34%), Gaps = 23/201 (11%) Query: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVP-------------PLSETEA 584 P E + + A APL +G P ++P P E EA Sbjct: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118 Query: 585 TPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644 + +++++ G D D A +P G +PA+ Sbjct: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178 Query: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPL 704 + P +S S + SG + P G P GT + P+ PP+ E K + Sbjct: 179 -----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAV 228 Query: 705 ATTQPAKTSTSKAKTQPTSLP 725 T P S++K++ Q +P Sbjct: 229 VRTPPKSPSSAKSRLQTAPVP 249 >gi|178557736 microtubule-associated protein tau isoform 5 [Homo sapiens] Length = 412 Score = 185 bits (470), Expect = 2e-46 Identities = 127/347 (36%), Positives = 167/347 (48%), Gaps = 71/347 (20%) Query: 754 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 804 + P ++ P+ + + I D + E A+ + S+S +K Sbjct: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116 Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863 K T A G ++ +T +P K P A KT E K +S S P S Sbjct: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173 Query: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923 T + T T P V TP K P+SAK SRL Sbjct: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214 Query: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982 T PDLKNV+SK+GSTEN+KHQPGGG Sbjct: 215 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 244 Query: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042 KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS Sbjct: 245 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 296 Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E Sbjct: 297 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 343 Score = 50.4 bits (119), Expect = 9e-06 Identities = 94/400 (23%), Positives = 141/400 (35%), Gaps = 58/400 (14%) Query: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657 Q G + E D G +P + T G+ + S ++ S E Sbjct: 26 QGGYTMHQDQEGDTDAGLKESP---LQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDT 82 Query: 658 PSELSSETSG-IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 716 PS L E +G + + GTG+D + + KTK +AT + A K Sbjct: 83 PS-LEDEAAGHVTQARMVSKSKDGTGSD------DKKAKGADGKTK-IATPRGAAPPGQK 134 Query: 717 AKTQPTSLPKQ--PAPTTIGGLNKKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKP 773 + T +P + PAP T + P S SG P P S PS+ +P Sbjct: 135 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194 Query: 774 KPIADAKAPEKRASPSKP--ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLP 831 K +A + P K S +K +AP K+ + + + ST P Sbjct: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK--------SKIGSTENLKHQPG---- 242 Query: 832 KKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKA 891 GK + K DLS +S S G + +V V Sbjct: 243 --------GGKVQIINK------KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDL 286 Query: 892 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPG 950 + + S+ + I KP + + +L D K+ V+SK+GS +NI H PG Sbjct: 287 SKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVPG 336 Query: 951 GGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988 GG K+E K T K + A P+ S P Sbjct: 337 GGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 376 Score = 33.5 bits (75), Expect = 1.2 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%) Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634 D P L + A V M +++++ G D D A +P G Sbjct: 81 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 139 Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694 +PA+ + P +S S + SG + P G P GT + P+ P Sbjct: 140 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 189 Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725 P+ E K + T P S++K++ Q +P Sbjct: 190 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 220 >gi|8400711 microtubule-associated protein tau isoform 3 [Homo sapiens] Length = 383 Score = 184 bits (468), Expect = 3e-46 Identities = 119/291 (40%), Positives = 149/291 (51%), Gaps = 62/291 (21%) Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLS 859 +K K T A G ++ +T +P K P A KT E K +S S Sbjct: 84 AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYS 140 Query: 860 RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 919 P S T + T T P V TP K P+SAK Sbjct: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK------- 182 Query: 920 LSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTA 978 SRL T PDLKNV+SK+GSTEN+KHQPGGG Sbjct: 183 -SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG-------------------------- 215 Query: 979 GPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSK 1038 KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SK Sbjct: 216 ------------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSK 263 Query: 1039 CGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 CGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E Sbjct: 264 CGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 314 Score = 110 bits (274), Expect = 1e-23 Identities = 87/293 (29%), Positives = 120/293 (40%), Gaps = 81/293 (27%) Query: 779 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 838 AK P +P P+S +SG +S + + S PS +P T PKK ++ Sbjct: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172 Query: 839 TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 898 T K K ++ P + K+ + S+ Sbjct: 173 TPPKSPSSAKSRLQTAPVPMPDLKN------------------------------VKSKI 202 Query: 899 STTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEK 958 +T + +P K +L DL NV+SK GS +NIKH PGGG Sbjct: 203 GSTENLKHQPGGGKVQIINKKL----------DLSNVQSKCGSKDNIKHVPGGG------ 246 Query: 959 KTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVP 1018 VQIV K V S + SKCGS NI H P Sbjct: 247 --------------------------------SVQIVYKPVDLSKVTSKCGSLGNIHHKP 274 Query: 1019 GGGNVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 1070 GGG V+++++K+D +V SK GS NI H PGGG+ KIE+ KL F+E A+AK Sbjct: 275 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 327 Score = 49.7 bits (117), Expect = 2e-05 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 53/317 (16%) Query: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737 GTG+D + + KTK +AT + A K + T +P + PAP T Sbjct: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128 Query: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP--ASA 794 + P S SG P P S PS+ +PK +A + P K S +K +A Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 188 Query: 795 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 854 P K+ + + + ST P GK + K Sbjct: 189 PVPMPDLKNVK--------SKIGSTENLKHQPG------------GGKVQIINK------ 222 Query: 855 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 914 DLS +S S G + +V V + + S+ + I KP + Sbjct: 223 KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE 280 Query: 915 STTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPES 971 + +L D K+ V+SK+GS +NI H PGGG K+E K T K + Sbjct: 281 VKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDH 330 Query: 972 NAVTKTAGPIASAQKQP 988 A P+ S P Sbjct: 331 GAEIVYKSPVVSGDTSP 347 Score = 33.5 bits (75), Expect = 1.2 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%) Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634 D P L + A V M +++++ G D D A +P G Sbjct: 52 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110 Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694 +PA+ + P +S S + SG + P G P GT + P+ P Sbjct: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160 Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725 P+ E K + T P S++K++ Q +P Sbjct: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191 >gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens] Length = 1827 Score = 147 bits (371), Expect = 6e-35 Identities = 209/849 (24%), Positives = 337/849 (39%), Gaps = 149/849 (17%) Query: 299 DMALVKDMELPTE--KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETER 356 + AL KD+ +PT+ E A P +V +K V + V DV + + Sbjct: 997 EQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPSKKVEQGLDFAVQGQLDVKISDFGQM 1056 Query: 357 ASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVP---AKDLVLL 413 AS + +D + ++ +P + D + G KE V K+ V Sbjct: 1057 ASGLNIDDRRATELKLEATQDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK 1116 Query: 414 SEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVA 473 ++ +A D S E SS E +L+ E+ A PE+++I + E+A Sbjct: 1117 PDLVHQEAVDKEESYE-SSGEHESLTMESLKADEGKKETSPESSLI---------QDEIA 1166 Query: 474 PVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKN 533 VK ++P D+A +V + P E++ +TP E + Sbjct: 1167 -VKLSVEIPCPPAVSEADLATDERADVQMEFIQGPKEESKETPDISITPSDVAEPLHETI 1225 Query: 534 VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDME 593 V P E++ E + + D + V+ A+ E P + Sbjct: 1226 VSEPAEIQSEEEEIEAQGEYDKLLFRSDTLQITDLGVSGAR------EEFVETCPSEHKG 1279 Query: 594 IAQTQKGISED--SHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGER 651 + ++ I +D + +++ D G+S + + + ++ S EE+ +E+ E Sbjct: 1280 VIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEVERRPSPHDEEEFEVEEAAEA 1339 Query: 652 K--PCNSQP-------------SELSSETSGIARPE--------EGRPVVSGTGNDITTP 688 + P + P SE +ET + E + + T +D + Sbjct: 1340 QAEPKDGSPEAPASPEREEVALSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSI 1399 Query: 689 PNKELP--PSPEKKTKPLATT--------QPAKTSTSKAKTQPTSLPKQPAPTTIG---- 734 ++L P EK K + +P KT + T + K+ P+T+ Sbjct: 1400 MTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRISTPERKVAKKE-PSTVSRDEV 1458 Query: 735 ----GLNKKPMSLASGLVPAAPPKR-----PAVASARPSIL-----------------PS 768 + KK V A P R PA+ RP+ L PS Sbjct: 1459 RRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPS 1518 Query: 769 --KDVKPKPIADA--KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSR 824 K K K ++D K+PEKR+S +P+S R G + + ++++S+ + Sbjct: 1519 VFKQAKDK-VSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTT 1577 Query: 825 SPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR-PKSTSTSSMKKTTTLSGTAPAAG 883 + + T P +T + P+ SR P + T S +T GT +A Sbjct: 1578 RSEPIRRAGKSGTSTPTTPGSTA-ITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAI 1636 Query: 884 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943 +VPS K + + P S TP+ RL N PDLKNV+SK+GST+ Sbjct: 1637 LVPSEKKVAIIRTPPK--------------SPATPKQLRLI-NQPLPDLKNVKSKIGSTD 1681 Query: 944 NIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSH 1003 NIK+QP GG+ VQIV+KK+ SH Sbjct: 1682 NIKYQPKGGQ--------------------------------------VQIVTKKIDLSH 1703 Query: 1004 IQSKCGSKDNIKHVPGGGNVQIQNKKVDIS-KVSSKCGSKANIKHKPGGGDVKIESQKLN 1062 + SKCGS NI+H PGGG V+I++ K+D K +K GS N H PGGG+VKI+SQKLN Sbjct: 1704 VTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLN 1763 Query: 1063 FKEKAQAKV 1071 F+E A+A+V Sbjct: 1764 FREHAKARV 1772 >gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sapiens] Length = 471 Score = 140 bits (353), Expect = 7e-33 Identities = 117/351 (33%), Positives = 159/351 (45%), Gaps = 94/351 (26%) Query: 748 VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 794 +P +PP PA A ++ PS K K K ++D K+PEKR+S +P+S Sbjct: 133 LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191 Query: 795 PASRSG-------------SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG 841 R G S + + +TT + + G S S T TAI T G Sbjct: 192 LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPT--TPGSTAI-TPG 248 Query: 842 KPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT 901 P T P + T S +T GT +A +VPS K + + P Sbjct: 249 TPPSYSSRT----------PGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK-- 296 Query: 902 PFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTE 961 S TP+ RL N PDLKNV+SK+GST+NIK+QP GG+ ++ Sbjct: 297 ------------SPATPKQLRL-INQPLPDLKNVKSKIGSTDNIKYQPKGGQVQI----- 338 Query: 962 AAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 1021 VTK K+ SH+ SKCGS NI+H PGGG Sbjct: 339 ------------VTK---------------------KIDLSHVTSKCGSLKNIRHRPGGG 365 Query: 1022 NVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKV 1071 V+I++ K+D K +K GS N H PGGG+VKI+SQKLNF+E A+A+V Sbjct: 366 RVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARV 416 Score = 128 bits (322), Expect = 3e-29 Identities = 109/327 (33%), Positives = 145/327 (44%), Gaps = 69/327 (21%) Query: 781 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840 A E P P +PAS T A+ G S+ +PS K ++ Sbjct: 127 AEETANLPPSPPPSPASEQ-----------TVTVEEAAGGESALAPSVFKQAKDKV--SD 173 Query: 841 GKPAEVKKMTAKSVPADLSRPK--------------STSTSSMKKTTTLSGTAPAAGVVP 886 G +K ++ P+ + P+ ++S SS + TT S AG Sbjct: 174 GVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGK-- 231 Query: 887 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 946 T P+ P +T P S SS TP + P Sbjct: 232 ---SGTSTPTTPGSTAITPGTPPSY--SSRTPGTPGTPSYPRTP---------------- 270 Query: 947 HQPGGGRAKV----EKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYS 1002 H PG ++ + EKK T P+S A K I QP ++ Sbjct: 271 HTPGTPKSAILVPSEKKVAIIRTP--PKSPATPKQLRLI----NQPLPDLK--------- 315 Query: 1003 HIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLN 1062 +++SK GS DNIK+ P GG VQI KK+D+S V+SKCGS NI+H+PGGG VKIES KL+ Sbjct: 316 NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLD 375 Query: 1063 FKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 FKEKAQAKVGSLDN H+P GG VK + Sbjct: 376 FKEKAQAKVGSLDNAHHVPGGGNVKID 402 >gi|8400715 microtubule-associated protein tau isoform 4 [Homo sapiens] Length = 352 Score = 128 bits (321), Expect = 4e-29 Identities = 85/236 (36%), Positives = 118/236 (50%), Gaps = 26/236 (11%) Query: 858 LSRPKSTSTSSMKKTTTLSGTAPAA---GVVPSRVKATPMPSR-PSTTPFIDKKPTSAKP 913 +S+ K + S KK G A G P K +R P+ TP K P P Sbjct: 70 VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----P 125 Query: 914 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973 SS P S + S+P T ++ P TR+P+ A Sbjct: 126 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----------------TREPKKVA 169 Query: 974 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033 V +T S+ K + + +++SK GS +N+KH PGGG VQI K VD+S Sbjct: 170 VVRTPPKSPSSAKSRLQTAPVPMPDLK--NVKSKIGSTENLKHQPGGGKVQIVYKPVDLS 227 Query: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089 KV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E Sbjct: 228 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283 Score = 56.6 bits (135), Expect = 1e-07 Identities = 60/221 (27%), Positives = 88/221 (39%), Gaps = 30/221 (13%) Query: 779 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 838 AK P +P P+S +SG +S + + S PS +P T PKK ++ Sbjct: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172 Query: 839 TEGKPAEVKKMTAKSVPA---DLSRPKST--STSSMKKTTTLSGTAPAAG---VVPSRVK 890 T K K ++ P DL KS ST ++K P G +V V Sbjct: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH-------QPGGGKVQIVYKPVD 225 Query: 891 ATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQP 949 + + S+ + I KP + + +L D K+ V+SK+GS +NI H P Sbjct: 226 LSKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVP 275 Query: 950 GGGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988 GGG K+E K T K + A P+ S P Sbjct: 276 GGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 316 Score = 35.0 bits (79), Expect = 0.41 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 10/114 (8%) Query: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737 GTG+D + + KTK +AT + A K + T +P + PAP T Sbjct: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128 Query: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK 790 + P S SG P P S PS+ +PK +A + P K S +K Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 182 Score = 33.5 bits (75), Expect = 1.2 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%) Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634 D P L + A V M +++++ G D D A +P G Sbjct: 52 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110 Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694 +PA+ + P +S S + SG + P G P GT + P+ P Sbjct: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160 Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725 P+ E K + T P S++K++ Q +P Sbjct: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 115 bits (288), Expect = 2e-25 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%) Query: 253 SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312 SKET + + K+ + TK K + K T AK+ Q S+E A KD+ PT K Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 192 Query: 313 EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371 +A PT ++ K L T E P T + +P + AP+ Sbjct: 193 VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 242 Query: 372 PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431 PKE T +++P PKE K+ + E A Sbjct: 243 TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 280 Query: 432 SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489 + K + T+ A T P E K A E AP P T PA Sbjct: 281 TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336 Query: 490 -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548 K+ AP+T KE P T P + P E T+ Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396 Query: 549 VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607 K AP T +P P T P P + A T K + + Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456 Query: 608 ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661 E + APT P ET T KK + E L KP + P EL Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 514 Query: 662 SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713 + T PEE P TTP PN P+P +P TT +PA T+ Sbjct: 515 APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568 Query: 714 ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759 T+ T PT+L PK+PAP + K+P S PK P Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819 P + P A K +P+ P PA + + +T +TT+ A T Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 687 Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879 P +P+T PK+P A T KPA T +++S P +T K+ TT+ + Sbjct: 688 TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 739 Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939 + + A P P +P PT+ P++T P ++ T+A D R Sbjct: 740 DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 788 Query: 940 GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999 +++ P A + E A TT K + +T T + S Q +I + K Sbjct: 789 ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844 Query: 1000 S 1000 + Sbjct: 845 T 845 Score = 105 bits (263), Expect = 2e-22 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%) Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245 H++ SP+ A+P P+P+ P L + KE + ++E G Sbjct: 109 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 168 Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304 KTT ++ E AKD+A +K E+ TK +T K+ P+ + A Sbjct: 169 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 228 Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345 E P E K P E ++ K T E AP Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288 Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398 T KE +P K K+ P PKE T + +P + AP+ P Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348 Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446 PKE K+ + E + + + + Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408 Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502 T P E + TK+ A E AP P T PA K+ AP+T K+ Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 465 Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562 +P + E A T P ET K + ++A T + PA T LA Sbjct: 466 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 516 Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622 TP + P E A P T K + + E + APT Sbjct: 517 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 565 Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682 +P+ T K + P + L++ P P EL+ T+ P + Sbjct: 566 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 613 Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 T P P +P+ +P TT T+ T PT+L K+PAPTT KKP Sbjct: 614 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 663 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801 L P + S +P+ K+ P P A K+ +P+ P + P + S Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723 Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861 + T + TT P +P L +PT E P E T K+ A ++P Sbjct: 724 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 775 Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917 + T+T+ K T L T P K T + +T I + TS TT Sbjct: 776 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 835 Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 P +++ L T T AP + + + +TE I ++P ++ T + ATT KP+ Sbjct: 836 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 888 Score = 91.7 bits (226), Expect = 4e-18 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%) Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251 V A +P +E+ A+ P +PT P + +E P T A Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 240 Query: 252 PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311 P+ E A + T + + P T K+ P+ + A PT Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 297 Query: 312 KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371 + + P T T P + KE +P + AP+ Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 355 Query: 372 PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429 P KE +P + +K+ P PKE PA + + + + Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 411 Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489 ++ ++ + ++ E A T P E K A E AP P T PA Sbjct: 412 PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467 Query: 490 ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543 K+ AP+T KE K ++P + ++A P P T P E+ Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 517 Query: 544 LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600 E+ P E AP K P P T P P E A T KG Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659 + + E + AP + T T C PA ++P + P Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637 Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719 E + T P + T P KEL P+ K P +TT T+ +T Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 692 Query: 720 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766 PT+ PK+PAPTT KKP + P PP K P P Sbjct: 693 APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743 Query: 767 PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800 P +P P A +P++ P+ P + A+ Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803 Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854 +K T T + TT + + +T S +T P K T +KT +V K +T + Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863 Query: 855 ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908 P + ++PK +T+S K TT P P + +T +P T P + K P Sbjct: 864 MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 916 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963 T K +ST P L+ P + + + +T P +V K+E A Sbjct: 917 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 963 Score = 69.3 bits (168), Expect = 2e-11 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%) Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744 PPN + T + +T+T+ +T K + + K K ++ Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 190 Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804 S ++ PK P + P A K +P+ SAP + T Sbjct: 191 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 250 Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862 T + TT A T +++ P+ PK+P T+ +PA +A + P + + PK Sbjct: 251 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 307 Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919 + ++ K+ TT P P+ P P+ P P KKP P P Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367 Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979 + T+ + K + K P + T++A TT K S TK Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427 Query: 980 PIASAQKQPA 989 P + K+PA Sbjct: 428 P--TTPKEPA 435 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 115 bits (288), Expect = 2e-25 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%) Query: 253 SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312 SKET + + K+ + TK K + K T AK+ Q S+E A KD+ PT K Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 233 Query: 313 EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371 +A PT ++ K L T E P T + +P + AP+ Sbjct: 234 VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 283 Query: 372 PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431 PKE T +++P PKE K+ + E A Sbjct: 284 TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 321 Query: 432 SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489 + K + T+ A T P E K A E AP P T PA Sbjct: 322 TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377 Query: 490 -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548 K+ AP+T KE P T P + P E T+ Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437 Query: 549 VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607 K AP T +P P T P P + A T K + + Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497 Query: 608 ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661 E + APT P ET T KK + E L KP + P EL Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 555 Query: 662 SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713 + T PEE P TTP PN P+P +P TT +PA T+ Sbjct: 556 APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609 Query: 714 ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759 T+ T PT+L PK+PAP + K+P S PK P Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819 P + P A K +P+ P PA + + +T +TT+ A T Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 728 Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879 P +P+T PK+P A T KPA T +++S P +T K+ TT+ + Sbjct: 729 TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 780 Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939 + + A P P +P PT+ P++T P ++ T+A D R Sbjct: 781 DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 829 Query: 940 GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999 +++ P A + E A TT K + +T T + S Q +I + K Sbjct: 830 ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885 Query: 1000 S 1000 + Sbjct: 886 T 886 Score = 105 bits (263), Expect = 2e-22 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%) Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245 H++ SP+ A+P P+P+ P L + KE + ++E G Sbjct: 150 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 209 Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304 KTT ++ E AKD+A +K E+ TK +T K+ P+ + A Sbjct: 210 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 269 Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345 E P E K P E ++ K T E AP Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329 Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398 T KE +P K K+ P PKE T + +P + AP+ P Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389 Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446 PKE K+ + E + + + + Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449 Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502 T P E + TK+ A E AP P T PA K+ AP+T K+ Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 506 Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562 +P + E A T P ET K + ++A T + PA T LA Sbjct: 507 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 557 Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622 TP + P E A P T K + + E + APT Sbjct: 558 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 606 Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682 +P+ T K + P + L++ P P EL+ T+ P + Sbjct: 607 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 654 Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 T P P +P+ +P TT T+ T PT+L K+PAPTT KKP Sbjct: 655 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 704 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801 L P + S +P+ K+ P P A K+ +P+ P + P + S Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764 Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861 + T + TT P +P L +PT E P E T K+ A ++P Sbjct: 765 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 816 Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917 + T+T+ K T L T P K T + +T I + TS TT Sbjct: 817 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 876 Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 P +++ L T T AP + + + +TE I ++P ++ T + ATT KP+ Sbjct: 877 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 929 Score = 91.7 bits (226), Expect = 4e-18 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%) Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251 V A +P +E+ A+ P +PT P + +E P T A Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 281 Query: 252 PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311 P+ E A + T + + P T K+ P+ + A PT Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 338 Query: 312 KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371 + + P T T P + KE +P + AP+ Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 396 Query: 372 PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429 P KE +P + +K+ P PKE PA + + + + Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 452 Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489 ++ ++ + ++ E A T P E K A E AP P T PA Sbjct: 453 PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508 Query: 490 ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543 K+ AP+T KE K ++P + ++A P P T P E+ Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 558 Query: 544 LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600 E+ P E AP K P P T P P E A T KG Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659 + + E + AP + T T C PA ++P + P Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678 Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719 E + T P + T P KEL P+ K P +TT T+ +T Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 733 Query: 720 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766 PT+ PK+PAPTT KKP + P PP K P P Sbjct: 734 APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784 Query: 767 PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800 P +P P A +P++ P+ P + A+ Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844 Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854 +K T T + TT + + +T S +T P K T +KT +V K +T + Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904 Query: 855 ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908 P + ++PK +T+S K TT P P + +T +P T P + K P Sbjct: 905 MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 957 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963 T K +ST P L+ P + + + +T P +V K+E A Sbjct: 958 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1004 Score = 69.3 bits (168), Expect = 2e-11 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%) Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744 PPN + T + +T+T+ +T K + + K K ++ Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 231 Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804 S ++ PK P + P A K +P+ SAP + T Sbjct: 232 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 291 Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862 T + TT A T +++ P+ PK+P T+ +PA +A + P + + PK Sbjct: 292 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 348 Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919 + ++ K+ TT P P+ P P+ P P KKP P P Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408 Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979 + T+ + K + K P + T++A TT K S TK Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468 Query: 980 PIASAQKQPA 989 P + K+PA Sbjct: 469 P--TTPKEPA 476 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 115 bits (288), Expect = 2e-25 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%) Query: 253 SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312 SKET + + K+ + TK K + K T AK+ Q S+E A KD+ PT K Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 285 Query: 313 EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371 +A PT ++ K L T E P T + +P + AP+ Sbjct: 286 VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 335 Query: 372 PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431 PKE T +++P PKE K+ + E A Sbjct: 336 TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 373 Query: 432 SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489 + K + T+ A T P E K A E AP P T PA Sbjct: 374 TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429 Query: 490 -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548 K+ AP+T KE P T P + P E T+ Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489 Query: 549 VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607 K AP T +P P T P P + A T K + + Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549 Query: 608 ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661 E + APT P ET T KK + E L KP + P EL Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 607 Query: 662 SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713 + T PEE P TTP PN P+P +P TT +PA T+ Sbjct: 608 APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661 Query: 714 ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759 T+ T PT+L PK+PAP + K+P S PK P Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819 P + P A K +P+ P PA + + +T +TT+ A T Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 780 Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879 P +P+T PK+P A T KPA T +++S P +T K+ TT+ + Sbjct: 781 TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 832 Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939 + + A P P +P PT+ P++T P ++ T+A D R Sbjct: 833 DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 881 Query: 940 GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999 +++ P A + E A TT K + +T T + S Q +I + K Sbjct: 882 ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 937 Query: 1000 S 1000 + Sbjct: 938 T 938 Score = 105 bits (263), Expect = 2e-22 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%) Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245 H++ SP+ A+P P+P+ P L + KE + ++E G Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261 Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304 KTT ++ E AKD+A +K E+ TK +T K+ P+ + A Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321 Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345 E P E K P E ++ K T E AP Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381 Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398 T KE +P K K+ P PKE T + +P + AP+ P Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441 Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446 PKE K+ + E + + + + Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501 Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502 T P E + TK+ A E AP P T PA K+ AP+T K+ Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 558 Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562 +P + E A T P ET K + ++A T + PA T LA Sbjct: 559 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 609 Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622 TP + P E A P T K + + E + APT Sbjct: 610 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 658 Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682 +P+ T K + P + L++ P P EL+ T+ P + Sbjct: 659 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 706 Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 T P P +P+ +P TT T+ T PT+L K+PAPTT KKP Sbjct: 707 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 756 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801 L P + S +P+ K+ P P A K+ +P+ P + P + S Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816 Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861 + T + TT P +P L +PT E P E T K+ A ++P Sbjct: 817 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 868 Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917 + T+T+ K T L T P K T + +T I + TS TT Sbjct: 869 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928 Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 P +++ L T T AP + + + +TE I ++P ++ T + ATT KP+ Sbjct: 929 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 981 Score = 91.7 bits (226), Expect = 4e-18 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%) Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251 V A +P +E+ A+ P +PT P + +E P T A Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 333 Query: 252 PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311 P+ E A + T + + P T K+ P+ + A PT Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 390 Query: 312 KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371 + + P T T P + KE +P + AP+ Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 448 Query: 372 PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429 P KE +P + +K+ P PKE PA + + + + Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 504 Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489 ++ ++ + ++ E A T P E K A E AP P T PA Sbjct: 505 PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560 Query: 490 ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543 K+ AP+T KE K ++P + ++A P P T P E+ Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 610 Query: 544 LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600 E+ P E AP K P P T P P E A T KG Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659 + + E + AP + T T C PA ++P + P Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730 Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719 E + T P + T P KEL P+ K P +TT T+ +T Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 785 Query: 720 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766 PT+ PK+PAPTT KKP + P PP K P P Sbjct: 786 APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836 Query: 767 PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800 P +P P A +P++ P+ P + A+ Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896 Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854 +K T T + TT + + +T S +T P K T +KT +V K +T + Sbjct: 897 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 956 Query: 855 ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908 P + ++PK +T+S K TT P P + +T +P T P + K P Sbjct: 957 MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 1009 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963 T K +ST P L+ P + + + +T P +V K+E A Sbjct: 1010 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056 Score = 69.3 bits (168), Expect = 2e-11 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%) Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744 PPN + T + +T+T+ +T K + + K K ++ Sbjct: 224 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283 Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804 S ++ PK P + P A K +P+ SAP + T Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343 Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862 T + TT A T +++ P+ PK+P T+ +PA +A + P + + PK Sbjct: 344 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 400 Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919 + ++ K+ TT P P+ P P+ P P KKP P P Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460 Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979 + T+ + K + K P + T++A TT K S TK Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520 Query: 980 PIASAQKQPA 989 P + K+PA Sbjct: 521 P--TTPKEPA 528 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 115 bits (288), Expect = 2e-25 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%) Query: 253 SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312 SKET + + K+ + TK K + K T AK+ Q S+E A KD+ PT K Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 326 Query: 313 EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371 +A PT ++ K L T E P T + +P + AP+ Sbjct: 327 VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 376 Query: 372 PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431 PKE T +++P PKE K+ + E A Sbjct: 377 TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 414 Query: 432 SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489 + K + T+ A T P E K A E AP P T PA Sbjct: 415 TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470 Query: 490 -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548 K+ AP+T KE P T P + P E T+ Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530 Query: 549 VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607 K AP T +P P T P P + A T K + + Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590 Query: 608 ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661 E + APT P ET T KK + E L KP + P EL Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 648 Query: 662 SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713 + T PEE P TTP PN P+P +P TT +PA T+ Sbjct: 649 APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702 Query: 714 ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759 T+ T PT+L PK+PAP + K+P S PK P Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819 P + P A K +P+ P PA + + +T +TT+ A T Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 821 Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879 P +P+T PK+P A T KPA T +++S P +T K+ TT+ + Sbjct: 822 TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 873 Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939 + + A P P +P PT+ P++T P ++ T+A D R Sbjct: 874 DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 922 Query: 940 GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999 +++ P A + E A TT K + +T T + S Q +I + K Sbjct: 923 ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 978 Query: 1000 S 1000 + Sbjct: 979 T 979 Score = 105 bits (263), Expect = 2e-22 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%) Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245 H++ SP+ A+P P+P+ P L + KE + ++E G Sbjct: 243 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302 Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304 KTT ++ E AKD+A +K E+ TK +T K+ P+ + A Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362 Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345 E P E K P E ++ K T E AP Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422 Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398 T KE +P K K+ P PKE T + +P + AP+ P Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482 Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446 PKE K+ + E + + + + Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542 Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502 T P E + TK+ A E AP P T PA K+ AP+T K+ Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 599 Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562 +P + E A T P ET K + ++A T + PA T LA Sbjct: 600 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 650 Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622 TP + P E A P T K + + E + APT Sbjct: 651 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 699 Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682 +P+ T K + P + L++ P P EL+ T+ P + Sbjct: 700 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 747 Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 T P P +P+ +P TT T+ T PT+L K+PAPTT KKP Sbjct: 748 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 797 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801 L P + S +P+ K+ P P A K+ +P+ P + P + S Sbjct: 798 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857 Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861 + T + TT P +P L +PT E P E T K+ A ++P Sbjct: 858 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 909 Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917 + T+T+ K T L T P K T + +T I + TS TT Sbjct: 910 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969 Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 P +++ L T T AP + + + +TE I ++P ++ T + ATT KP+ Sbjct: 970 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 1022 Score = 91.7 bits (226), Expect = 4e-18 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%) Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251 V A +P +E+ A+ P +PT P + +E P T A Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 374 Query: 252 PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311 P+ E A + T + + P T K+ P+ + A PT Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 431 Query: 312 KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371 + + P T T P + KE +P + AP+ Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 489 Query: 372 PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429 P KE +P + +K+ P PKE PA + + + + Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 545 Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489 ++ ++ + ++ E A T P E K A E AP P T PA Sbjct: 546 PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601 Query: 490 ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543 K+ AP+T KE K ++P + ++A P P T P E+ Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 651 Query: 544 LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600 E+ P E AP K P P T P P E A T KG Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711 Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659 + + E + AP + T T C PA ++P + P Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771 Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719 E + T P + T P KEL P+ K P +TT T+ +T Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 826 Query: 720 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766 PT+ PK+PAPTT KKP + P PP K P P Sbjct: 827 APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877 Query: 767 PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800 P +P P A +P++ P+ P + A+ Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937 Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854 +K T T + TT + + +T S +T P K T +KT +V K +T + Sbjct: 938 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 997 Query: 855 ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908 P + ++PK +T+S K TT P P + +T +P T P + K P Sbjct: 998 MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 1050 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963 T K +ST P L+ P + + + +T P +V K+E A Sbjct: 1051 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097 Score = 69.3 bits (168), Expect = 2e-11 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%) Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744 PPN + T + +T+T+ +T K + + K K ++ Sbjct: 265 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324 Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804 S ++ PK P + P A K +P+ SAP + T Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384 Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862 T + TT A T +++ P+ PK+P T+ +PA +A + P + + PK Sbjct: 385 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 441 Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919 + ++ K+ TT P P+ P P+ P P KKP P P Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501 Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979 + T+ + K + K P + T++A TT K S TK Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561 Query: 980 PIASAQKQPA 989 P + K+PA Sbjct: 562 P--TTPKEPA 569 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 95.9 bits (237), Expect = 2e-19 Identities = 157/736 (21%), Positives = 270/736 (36%), Gaps = 93/736 (12%) Query: 206 PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMA 265 PE +P VP+ K++E PPA+ E+ L + P+ + A Sbjct: 10033 PEVPKKPVPEKKVPVPAPKKVEA-----PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK 10087 Query: 266 LATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTE 325 + K E P + V L ++ + E ++ +++ LP E+EV ++ P E Sbjct: 10088 VPKKRE---------PVPVPVALPQEEEVLFEEEIVPEEEV-LPEEEEVLPEEEEVLPEE 10137 Query: 326 TDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGP-----PKENKKET 380 +V + + P E EV P ++ + E E P + L K P P+ KK T Sbjct: 10138 EEVLPEEEEIPPEEEEVPPEEEY--VPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVT 10195 Query: 381 ER--ASPIKMDLAPSKDMGPPKENK----IVPAKDLVLLSEIEVAQANDIISSTEISSAE 434 E+ P K + P+K PK+ + I+P ++ VL E+ + IS EI E Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE-E 10254 Query: 435 KVALSSETEVALARDMTLPPETNVILTK-----DKALPLEAEVAPVKDMAQLPETEI--- 486 ++ EVA PP ++ K +P + E P K ++PE ++ Sbjct: 10255 PPSIEEVEEVA-------PPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVP 10307 Query: 487 APAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTE 546 K+ P+ V EV K V PE +V++ K +PP + E Sbjct: 10308 VQKKEAPPAKVPEVP----------------KKV---PEKKVLVPKKEAVPPAKGRTVLE 10348 Query: 547 DQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSH 606 ++V + + K+ L L +++P E ++ E + ++ I + H Sbjct: 10349 EKVSVAFRQEVVVKER-LELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQH 10407 Query: 607 LESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETS 666 + + + +K P + + EK+ P P+++ Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI---IPPKKPPTKVVPRKE 10464 Query: 667 GIAR-PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725 A+ PE + +V + P +PP+ + P P K K P P Sbjct: 10465 PPAKVPEVPKKIV--VEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK----KVPVPPAKKP 10518 Query: 726 KQPAPTTIGGLNKKPMSLA-SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784 + P P + + P + VP PPK+P V + +P V K + +A P+ Sbjct: 10519 EAPPPK----VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP 10574 Query: 785 RASPSKPASAPASRSGSKSTQTV--AKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 842 + P + AP K K P P +P P K E Sbjct: 10575 ESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPK-KPEVP 10633 Query: 843 PAEVKKMTAKSVP------ADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 896 P +V ++ +VP A +P+S ++ ++ P P+ V P P+ Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP-----PAEVVEEPEPA 10688 Query: 897 RPSTTPFIDKKPTSAK 912 P KKP K Sbjct: 10689 APPQVTVPPKKPVPEK 10704 Score = 88.2 bits (217), Expect = 4e-17 Identities = 167/657 (25%), Positives = 253/657 (38%), Gaps = 125/657 (19%) Query: 198 PHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETE 257 P + V P V E P+ AVP + E E PP + E ++ P K+ Sbjct: 10542 PPKKPEVPPTKVPEVPK-AAVPEKKVPEAIPPKPESPPPEVPEA-----PKEVVPEKKVP 10595 Query: 258 MALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT----EKE 313 A K K EV K E+P ++ + P + ++ K E+P EK+ Sbjct: 10596 AAPPK------KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649 Query: 314 V--ALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371 V A+ P + V L E PA+ +++E E A+P ++ + P K Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVAL----EEPPAE---VVEEPEPAAPPQVTVPPKK--- 10699 Query: 372 PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKD--LVLLSEIEVAQANDIISSTE 429 P E K A K +L P K PKE +VP K LV+ + E A E Sbjct: 10700 PVPEKKAPAVVAK--KPELPPVKVPEVPKE--VVPEKKVPLVVPKKPEAPPAKVPEVPKE 10755 Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPL-EAEVAPVKDMAQLPETEIAP 488 + +KVA+ + EV A+ +P + +L + A+P+ E +P ++ + PE EIAP Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKP--VLEEKPAVPVPERAESPPPEVYEEPE-EIAP 10812 Query: 489 AKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548 +++AP K V P++E E + PPP +P E + + E + Sbjct: 10813 EEEIAPEEEKPV-------PVAEEE----EPEVPPP----------AVPEEPKKIIPEKK 10851 Query: 549 VPALKT-EAPLAKDGVLTLANNVTPAKDV--PPLSETEATPVPIKDMEIAQTQKGISEDS 605 VP +K EAP K+ P K + P L P P E + + Sbjct: 10852 VPVIKKPEAPPPKEP--------EPEKVIEKPKLKPRPPPPPPAPPKEDVKEK------- 10896 Query: 606 HLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET 665 + L+ + + P PE V T K +P E V + L ERKP + L S Sbjct: 10897 -IFQLKAIPKKKVPEKPQVPEKVELTPLK--VPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953 Query: 666 SGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ-PAKTSTSKAKTQPTSL 724 RPEE P V + P PP P KP+ + P T + +PT + Sbjct: 10954 R--KRPEEEEPKVEPKKLEKVKKPAVPEPPPP----KPVEEVEVPTVTKRERKIPEPTKV 11007 Query: 725 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784 P+ + PA P LP+ + KPKP A+ K Sbjct: 11008 PE--------------------IKPAIP-------------LPAPEPKPKPEAEVKT--I 11032 Query: 785 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTE 840 + P +P P + + V K A A + P +PKK P+ I+ E Sbjct: 11033 KPPPVEPEPTPI--AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAE 11087 Score = 79.3 bits (194), Expect = 2e-14 Identities = 196/899 (21%), Positives = 306/899 (34%), Gaps = 141/899 (15%) Query: 151 DLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVA 210 +++F + + + + L + + P V+P+ E + PE Sbjct: 10106 EVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE------------EEEIPPEEEE 10153 Query: 211 EPPQPTAVPLE--LAKEIEMASEERP----PAQALEIMMGLKTTDMAPSKETEMALAKDM 264 PP+ VP E E E+ E +P PA EI + + K+ E AK Sbjct: 10154 VPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVP 10213 Query: 265 ALATKTE---VALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR 321 + K E + L K+ E ++VT + +P E ++ E P+ +EV V R Sbjct: 10214 EVPKKVEEKRIILPKE-EEVLPVEVTEEPEEEPISEEEIP----EEPPSIEEVEEVAPPR 10268 Query: 322 WPT--ETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKE 379 P + V A V P + E PAK + E + P++ AP + + E Sbjct: 10269 VPEVIKKAVPEAPTPV-PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE 10327 Query: 380 TERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLS---EIEV--AQANDIISSTEISSA- 433 + P K + P+K +E V + V++ E+EV A+ +I E Sbjct: 10328 KKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387 Query: 434 -----------------EKVALSSETEVALARDM--TLPPETNVILTKDKALPLEAEVAP 474 E+ + E V + E + K KA P E++ Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE 10447 Query: 475 VKDMAQLPETEIAPAKDVAPSTVKEVG---LLKD---------MSPLSETEMALGKDVTP 522 + P T++ P K+ P+ V EV ++++ + P E+ K+V P Sbjct: 10448 KIIPPKKPPTKVVPRKE-PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP 10506 Query: 523 PPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG------VLTLANNVTPAKDV 576 + V K PP ++ VP K P K V + P K V Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566 Query: 577 P----PLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETV-TGT 631 P P E+ VP E+ +K + + V AP ++ + V Sbjct: 10567 PEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626 Query: 632 GKKCSLPAEEDSVLEKLG--ERK-------PCNSQPSELSSETSGIARPEEGRPVVS--- 679 KK +P + + K+ E+K S P E+ E +A E VV Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE 10686 Query: 680 -GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK 738 +T PP K P PEKK + +P + P +P+ P + + Sbjct: 10687 PAAPPQVTVPPKK---PVPEKKAPAVVAKKP--------ELPPVKVPEVPKEV----VPE 10731 Query: 739 KPMSLASGLVPAAPPKRPAVASARPSILPSKDV---KPKPIADAKAPE---KRASPSKPA 792 K + L P APP + V ++P K V K + AK PE K KPA Sbjct: 10732 KKVPLVVPKKPEAPPAK--VPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789 Query: 793 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKK-MTA 851 R+ S + + A P P + ++ + P E KK + Sbjct: 10790 VPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPE 10849 Query: 852 KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA 911 K VP +KK P V + K P P P P + Sbjct: 10850 KKVPV------------IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKI 10897 Query: 912 KPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 P+ P+ V KV T PGG EKK RKPE Sbjct: 10898 FQLKAIPK-------KKVPEKPQVPEKVELTP--LKVPGG-----EKKVRKLLPERKPE 10942 Score = 77.0 bits (188), Expect = 9e-14 Identities = 170/741 (22%), Positives = 273/741 (36%), Gaps = 92/741 (12%) Query: 205 SPEAVAEPPQPT-AVPLELAKEIEMASEERPPAQALE----------IMMGLKTTDMAPS 253 +P P +P AVP E +++ EE PPA+ E + + + P Sbjct: 9658 APPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI 9717 Query: 254 KETEMALAKDMALATKTE---VALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310 KE + K+ A + E V ++ E + D ++ +P+ E D E Sbjct: 9718 KEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYD-----QYEEYE 9772 Query: 311 EKEVALVKD-VRWPTETD----VSSAKNVVLPTETEVAPAKDVTLLKETERAS---PIKM 362 E+E ++ + TE + V +PT+ + PAK + E+ P K+ Sbjct: 9773 EREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKL 9832 Query: 363 DLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQ 420 P K PK+ +E R S K + + P + K V A++ V + EVA Sbjct: 9833 KPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAP 9892 Query: 421 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480 + + E+VA E EV + L E + +++ E EV PV + + Sbjct: 9893 PVRVPEVPKELEPEEVAF--EEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPV-K 9949 Query: 481 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEV-VLIKNVCLPPE 539 +PE P K V P K V + K E A +V PE +V VLI PP Sbjct: 9950 VPE---VPRKPV-PEEKKPVPVPKK----KEAPPAKVPEVPKKPEEKVPVLIPKKEKPPP 10001 Query: 540 MEV------ALTEDQVPA---LKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIK 590 +V + E++VP K EAP AK V + P K VP + + P K Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAK--VPEVPKKPVPEKKVPVPAPKKVEAPPAK 10059 Query: 591 DMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEK--L 648 E+ +K I E+ + ++ P E V +LP EE+ + E+ + Sbjct: 10060 VPEV--PKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP---VPVALPQEEEVLFEEEIV 10114 Query: 649 GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ 708 E + + L E + EE P +E+PP E+ Sbjct: 10115 PEEEVLPEEEEVLPEEEEVLPEEEE------------VLPEEEEIPPEEEEVPPEEEYVP 10162 Query: 709 PAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK------PMSLASGLVPAAPPKRPAVASAR 762 + + + P PK P P + + KK + PA P+ P + Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222 Query: 763 PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 822 ILP K+ + P+ + PE+ P P + + VA + P Sbjct: 10223 RIILP-KEEEVLPVEVTEEPEE--EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279 Query: 823 SRSPSTLLPKKPTAIKTEGKPAEV-KKMTAKSVPADLSR---PKSTSTSSMKKTTTLSGT 878 + +P +PK K E PA+V KK+ + VP + + P + KK Sbjct: 10280 APTP---VPK-----KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL 10331 Query: 879 APAAGVVPSRVKATPMPSRPS 899 P VP T + + S Sbjct: 10332 VPKKEAVPPAKGRTVLEEKVS 10352 Score = 73.9 bits (180), Expect = 8e-13 Identities = 116/543 (21%), Positives = 209/543 (38%), Gaps = 52/543 (9%) Query: 204 VSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALA-- 261 V +AV E P +P +L EE P + E + + T + TE A Sbjct: 9814 VLKKAVPEEKVPVPIPKKLKPPPPKVPEE--PKKVFEEKIRISITKREKEQVTEPAAKVP 9871 Query: 262 -KDMALATKTEVALAKDMESPTKLDVTLAKDMQP---SMESDMALVKDMELPTEKEVALV 317 K + + +V + + +P + K+++P + E ++ + L E+E + Sbjct: 9872 MKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIH 9931 Query: 318 KDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPK--- 374 ++ + TE +V V+P + P K V E P+ + P K PP Sbjct: 9932 EEEEFITEEEVVP----VIPVKVPEVPRKPVP-----EEKKPVPV---PKKKEAPPAKVP 9979 Query: 375 ENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLS-EIEVAQANDIISSTEISSA 433 E K+ E P+ L P K+ PP + VP K + + V + + + Sbjct: 9980 EVPKKPEEKVPV---LIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVP 10036 Query: 434 EKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVA 493 +K + V + + PP V K +P E + PV + P ++ ++ Sbjct: 10037 KKPVPEKKVPVPAPKKVEAPP-AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPV 10095 Query: 494 PSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALK 553 P V L ++ L E E+ ++V P E EV+ + LP E EV E+++P + Sbjct: 10096 PVPV---ALPQEEEVLFEEEIVPEEEVLPEEE-EVLPEEEEVLPEEEEVLPEEEEIPPEE 10151 Query: 554 TEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDV 613 E P ++ V V + +P + P P+ +++ T+K + E Sbjct: 10152 EEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEE----- 10206 Query: 614 GQSAAPTFMISPETVTGTGKKCSLPAEEDSV---LEKLGERKPCNSQPSELSSETSGIAR 670 AP + K+ LP EE+ + + + E +P + + E+ E I Sbjct: 10207 ----APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEE--EIPEEPPSIEE 10260 Query: 671 PEEGRP-----VVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725 EE P V+ + TP K++ P K +K + + K + P +P Sbjct: 10261 VEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKI-PEEKVPVPVQKKEAPPAKVP 10319 Query: 726 KQP 728 + P Sbjct: 10320 EVP 10322 Score = 54.3 bits (129), Expect = 7e-07 Identities = 158/767 (20%), Positives = 268/767 (34%), Gaps = 161/767 (20%) Query: 209 VAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALAT 268 V PP P +P E++PP + +E+ T A K+ + +AK + Sbjct: 8960 VVAPPIPLLLPTP--------EEKKPPPKRIEV------TKKAVKKDAKKVVAKPKEMTP 9005 Query: 269 KTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDV 328 + E+ K PT L A ++ + S VK M + +KEV K+ + + V Sbjct: 9006 REEIV--KKPPPPTTLIPAKAPEII-DVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAV 9062 Query: 329 SSAKNVVLPT------ETEVAPA----------------KDVTLLKETERASPIKMDLAP 366 K V + + E EV P +++ + + E + D Sbjct: 9063 HKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEE 9122 Query: 367 SKDMGPPKEN----KKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQAN 422 ++ +E ++E E A + + K++ + VPAK + E + Sbjct: 9123 GQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAK----VPEKKAPPPP 9178 Query: 423 DIISSTEISSAEKVALSSETEVALARDMTLPPETN--VILTKDKALPLEAEVAPVKDMAQ 480 +I I EK + E E +T PE + ++ K P++ EV VK A Sbjct: 9179 KVIKKPVIEKIEKTSRRMEEEKV---QVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAV 9235 Query: 481 LPETEIAPAKDV--APSTVKEVGLL-----KDMSPLSETEMALGKDVTPPPETEVVLIKN 533 + + + + A T +EV + K++ + +A+ K V PPP+ + K Sbjct: 9236 HTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEK- 9294 Query: 534 VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDME 593 P EVA +P K E P K + P K VP E PVP+ E Sbjct: 9295 ---PAPEEVAPVP--IPK-KVEPPAPKVPEV-------PKKPVPE----EKKPVPVPKKE 9337 Query: 594 IAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKP 653 A +P V KK P E+ + + ++K Sbjct: 9338 PA----------------------------APPKVPEVPKK---PVPEEKIPVPVAKKK- 9365 Query: 654 CNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 713 + P+++ G+ E+ + T + + PP +P P+KK Sbjct: 9366 -EAPPAKVPEVQKGVVTEEK---ITIVTQREESPPP--AVPEIPKKKVP----------- 9408 Query: 714 TSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPA-----APPKRPAVASARPSILPS 768 + K P + P P + L KKP+ VP APP R V ++ +++ Sbjct: 9409 -EERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEV--SKKTVVEE 9465 Query: 769 KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA--------KTTTAAAVASTG 820 K + P++ SA S S+ + V+ + A + Sbjct: 9466 KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEY 9525 Query: 821 PSSRSPSTLLPKKPTAI---KTEGKPAEV-----KKMTAK-SVPADLSRPKSTSTSSMKK 871 P + ++ I + E +PAEV KK+ K +PA + P K Sbjct: 9526 EVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPK 9585 Query: 872 TTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 918 PA VP + K P P + ++P P P Sbjct: 9586 KIVPEKKVPAP--VPKKEKVPP--------PKVPEEPKKPVPEKKVP 9622 Score = 52.8 bits (125), Expect = 2e-06 Identities = 156/718 (21%), Positives = 273/718 (38%), Gaps = 95/718 (13%) Query: 207 EAVAEPPQPTAVPLELAKEIEMA-----SEERPPAQALEIMMGLKTTDMAPSKETEMALA 261 E V PP+ A+P + E ++A +++ PP +A E+ + E +++ A Sbjct: 9419 EEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRA-EVSKKTVVEEKRFVAEEKLSFA 9477 Query: 262 KDMAL-ATKTEVALAKDM-----ESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVA 315 + T+ EV+ ++ E + V ++ + E+++ + ME P E V Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537 Query: 316 -----LVKDVRW-PTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKD 369 + K V P E K +VL + PAK E P K+ AP K Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKIVLKPKI---PAK-------IEEPPPAKVPEAPKKI 9587 Query: 370 MGPPKENKK--ETERASPIKMDLAPSKDMG----PPKENKI---VPAKDLVLLSEIEVAQ 420 + K + E+ P K+ P K + PPK K+ +PAK V +++ Q Sbjct: 9588 VPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAK--VTERHMQITQ 9645 Query: 421 ANDI-ISSTEISSAEKVALSSETEVALARDMTL---------PP----ETNVILTKDKAL 466 + ++ T+ + K + E + A+ + L PP E + K++ + Sbjct: 9646 EEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705 Query: 467 PLEA---EVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP 523 +EA E P+K++ + E E A + +V+ ++ E + Sbjct: 9706 SIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEY 9765 Query: 524 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 583 + E + E E +TE + P P+ ++ V T PAK + E Sbjct: 9766 DQYEEYEEREYERYEEHEEYITEPEKPI--PVKPVPEEPVPTKPK-APPAKVLKKAVPEE 9822 Query: 584 ATPVPIKDM------EIAQTQKGISEDSHLESL-----QDVGQSAAPTFMISPETVTGTG 632 PVPI ++ + K + E+ S+ + V + AA M P+ V Sbjct: 9823 KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPM-KPKRVVAE- 9880 Query: 633 KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692 +K +P +E + ++ E P +P E++ E + EE +V I ++E Sbjct: 9881 EKVPVPRKEVAPPVRVPE-VPKELEPEEVAFEEEVVTHVEEY--LVEEEEEYI----HEE 9933 Query: 693 LPPSPEKKTKPLATTQ----PAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 748 E++ P+ + P K + K P K+ P + + KKP V Sbjct: 9934 EEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP----EEKV 9989 Query: 749 PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 808 P PK+ A+ +P K V + + + A P+K P K A Sbjct: 9990 PVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049 Query: 809 KTTTAAAVASTGPSSRSPSTLLP--KKPTAI--KTEGKPAEVKKMTAKSVPADLSRPK 862 A A P L+P KKPT + K E P +V K + VP ++ P+ Sbjct: 10050 PKKVEAPPAKV---PEVPKKLIPEEKKPTPVPKKVEAPPPKVPK-KREPVPVPVALPQ 10103 Score = 45.8 bits (107), Expect = 2e-04 Identities = 163/810 (20%), Positives = 304/810 (37%), Gaps = 111/810 (13%) Query: 141 FKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHS 200 F++ + DL L+ + D+ ++ +S G + ++ QG E + + + Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVN---ATNSVGRATSTAELLVQG--EEEVPAKKT 204 Query: 201 ESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMAL 260 ++ VS ++E Q + K+IE + R A ++ G A Sbjct: 205 KTIVSTAQISESRQT-----RIEKKIEAHFDARSIATVEMVIDG--------------AA 245 Query: 261 AKDMALATKTEVALAKDMESPTKLDVT----LAKDMQPSMESDMALVKDMELPTEKEVAL 316 + + T + SPT + LA+ PS P + Sbjct: 246 GQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPS-------------PIRHSPSP 292 Query: 317 VKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKEN 376 V+ VR PT + V S + + + + L+++T+ ++ +A ++ PP + Sbjct: 293 VRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQAST-----VATGPEVPPPWKQ 347 Query: 377 KKETERASPIKM---DLAPSKDMGPPKE-NKIVPAKDLVLLSEIEVAQANDIISSTEISS 432 + +S +M L S + + ++ V +S A A+ +S++ + Sbjct: 348 EGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAAS--VSASASYA 405 Query: 433 AEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPET---EIAPA 489 AE VA ++ EV D + T V+ D A E ++ V+ AQ T I PA Sbjct: 406 AEAVATGAK-EVKQDADKSAAVAT-VVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPA 463 Query: 490 -----KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPE------------TEVVLIK 532 K+ + V +V + D + E + + +T E TE + Sbjct: 464 QEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVP 523 Query: 533 NVCLPP----EMEVALTEDQVPALK--TEAPLAKDGVLTLANNVTPAKDVPPLSETEATP 586 V + E E ++E+ K T+ + ++ +T A+ V A ++ E P Sbjct: 524 KVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVA--TAKSTKLETVP 581 Query: 587 VPIKDMEIAQTQKGISEDSHLESLQD--VGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644 ++ Q Q +S + ++ + V + T + + + G++ E Sbjct: 582 GAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQ 641 Query: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPE---KKT 701 + + RK ++ + LS+ A+ +E ++ T ++ KK Sbjct: 642 ITQEKMRK--EAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKA 699 Query: 702 KPLATTQPAKTSTS-KAKTQPTSLPKQPAP-TTIGGLNKKPMSLASGLVPAAPPKRPAVA 759 + +AT A + +P L + A TT+ K+ +S A A PP+RPA Sbjct: 700 EAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAK---VAEPPQRPA-- 754 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819 + P ++P K VKP+ I +AP + + K S+ +T TT Sbjct: 755 -SEPHVVP-KAVKPRVI---QAPSE--THIKTTDQKGMHISSQIKKTTDLTTERLVHVDK 807 Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879 P + SP + K G A + A S A L + S ++S+ K T ++ A Sbjct: 808 RPRTASPHFTVSKISVPKTEHGYEASI----AGSAIATLQKELSATSSAQKITKSVK--A 861 Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPT 909 P +RV+A P P PF D T Sbjct: 862 PTVKPSETRVRAEPTPL--PQFPFADTPDT 889 Score = 33.9 bits (76), Expect = 0.92 Identities = 50/230 (21%), Positives = 79/230 (34%), Gaps = 26/230 (11%) Query: 779 AKAPEKRASP-----SKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 833 AK PEK+A P KP ++ + + + T V+ ++P+K Sbjct: 9167 AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKK---------IVPQK 9217 Query: 834 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP 893 P+ + + EVK + +S K S ++ +++ +V Sbjct: 9218 PSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVA 9277 Query: 894 MPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 953 + R P + + P P P AP + V K E K P Sbjct: 9278 ISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK-KPVP---- 9332 Query: 954 AKVEKKTEAAATTRKPE----SNAVTKTAGPIASAQKQPAGKVQIVSKKV 999 V KK E AA + PE K P+A ++ P KV V K V Sbjct: 9333 --VPKK-EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379 Score = 32.3 bits (72), Expect = 2.7 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 13/113 (11%) Query: 650 ERKPCNSQPSELSSETSGIAR--PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATT 707 E KP + S + T I PEE PVV+ PP L P+PE+K P Sbjct: 8931 ELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVA--------PPIPLLLPTPEEKKPPPKRI 8982 Query: 708 QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760 + K + K + + PK+ P + KKP + L+PA P+ V+S Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPRE--EIVKKPPP-PTTLIPAKAPEIIDVSS 9032 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 87.8 bits (216), Expect = 5e-17 Identities = 215/1042 (20%), Positives = 351/1042 (33%), Gaps = 157/1042 (15%) Query: 58 GNSESKKKPCS-------ETSQIEDTP---SSKPTLLANGGHGVEGSDTTGSPTEFLEEK 107 GN+ + P S ETS + TP S+ T + G +D T PT E Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG 2395 Query: 108 MAYQEYPNSQNWP----EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSS----AT 159 P E + P P+ T P+S T Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455 Query: 160 ADTSIFAGQNDPLKDSYGMSPCNTAV---VPQGWSVEALNSPHS-ESFVSPEAVAEPPQ- 214 + P+ S + T V P S EA +SP + E V P + A Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGST 2515 Query: 215 ----------PTAVPLELAKEIEMASEERPPAQALEIMMGLKT---TDMAPSKETEMALA 261 P A P P + EI + T M S +E + Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575 Query: 262 -KDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDV 320 + M ++TK + S T +D ++ S KD +P Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIS--------- 2626 Query: 321 RWPTETDVSSAKNVVLPTETEVAPAKDVTLLK-----ETERASPIKMDLAPSKDMGPPKE 375 T ++VS++ +L + VA ++ TL T + +P+ G Sbjct: 2627 ---TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683 Query: 376 NKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEK 435 ER++P+ L + ++ + LS V + + +S E SS+ Sbjct: 2684 TSTPGERSTPLTNILVSTT---------LLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734 Query: 436 VALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPS 495 A + ++ D + P + ++ T A + V+ +P T A +P+ Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASS-SPT 2793 Query: 496 TVKEVGLLKDMSPLSETEMALGK---DVTPPPETEVVLIKNVCLPPEMEVALTEDQVPAL 552 T EV + +P SET L + TP +E + P + +T Sbjct: 2794 TA-EVTSMPTSTP-SETSTPLTSMPVNHTPVASSEAGTLSTT--PVDTSTPVTTS---TK 2846 Query: 553 KTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQD 612 + +P +G++ + + T T +P+ +A ++ + +++ Sbjct: 2847 ASSSPTTAEGIVVPISTASEGS-------TLLTSIPVSTTPVASSEASTLSTTPVDTSIP 2899 Query: 613 VGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKL---------GERKPCNSQPSELSS 663 V S + SP T GT S P+E + L + E ++ P + + Sbjct: 2900 VTTSTEGSS--SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRT 2957 Query: 664 ETSGIARPEEGRPVVSGTGNDITTPPNKELP-PSPEKKTKPLATTQPAKTSTSKAKTQP- 721 + A GT I+TP + P S T P+A+++ + S + A T Sbjct: 2958 PVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017 Query: 722 --TSLPKQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDVKPK-PI 776 TS +PTT G + + G P + P VA S L + V P+ Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077 Query: 777 ADAKAPEKRASPSKPASAPASRSGSKST-------QTVAKTTTAAAVASTGP-------- 821 + +P++ S P S ST T T++A + ST P Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137 Query: 822 ----SSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLSRPKST 864 + SP+T PT+ +EG + T + P D S P +T Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTT 3197 Query: 865 STSSMKKT----TTLSGTAPAAGVVPSR---VKATPMPSRP----STTPFIDKKP--TSA 911 ST + T T++ + P+ G+ P V TP+ S STTP P TS Sbjct: 3198 STEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST 3257 Query: 912 KPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPES 971 + SS+ P + TS P GST + P +T +TT S Sbjct: 3258 EASSSPPTAEGTSMPTSTP-------SEGSTP-LTSMPVSTTTVASSETSTLSTTPADTS 3309 Query: 972 NAVT-----KTAGPIASAQKQP 988 VT ++ PIA P Sbjct: 3310 TPVTTYSQASSSPPIADGTSMP 3331 Score = 82.0 bits (201), Expect = 3e-15 Identities = 174/806 (21%), Positives = 296/806 (36%), Gaps = 104/806 (12%) Query: 205 SPEAVAEPP--QPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAK 262 S EA + PP + T++P E P + + T P+ + Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076 Query: 263 DMALATKTEVALAKDMESPTKLDVTLAKDMQP--SMESDMALVKDMELPTEKEVALVKDV 320 A ++ T A PT T ++ P S+ LV E T + + Sbjct: 1077 SQASSSSTT---ADGTSMPTS---TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI 1130 Query: 321 RWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERAS-PIKMDLAPSKDMGP----PKE 375 T T+ SS+ T +P + T T AS P+ L S + P + Sbjct: 1131 PVTTSTEASSSPTTAEGTSIPTSPPSEGT----TPLASMPVSTTLVVSSEANTLSTTPVD 1186 Query: 376 NKKE----TERASPIKMDLAPSKDMGPPKENKI----VPAKDL-VLLSEIEVAQANDIIS 426 +K + TE +SP S P E +P + V SE + + + Sbjct: 1187 SKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246 Query: 427 STEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEI 486 ST ++++ + + S T + + E + +LT ++P+ + + + L T + Sbjct: 1247 STPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLT---SIPVSTTLVTSPEASTLLTTPV 1303 Query: 487 ------APAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540 + +V+ S G S SE L + P T +V + + + Sbjct: 1304 DTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPL---TSIPVNTTLVASSAISI---L 1357 Query: 541 EVALTEDQVPAL-KTEA---PLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596 ++ P TEA P +G T N P++ PL+ + P+ E A Sbjct: 1358 STTPVDNSTPVTTSTEACSSPTTSEG--TSMPNSNPSEGTTPLTSIPVSTTPVVSSE-AS 1414 Query: 597 TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKL--GERKPC 654 T D+ +++PT T G S P+E + L+ + Sbjct: 1415 TLSATPVDTSTPGTTSAEATSSPT------TAEGISIPTSTPSEGKTPLKSIPVSNTPVA 1468 Query: 655 NSQPSELSSETSGIARPEEGRPVVS-------GTGNDITTPPNKELPPSPEKKTKPLATT 707 NS+ S LS+ P VS GT I+TP S + P++TT Sbjct: 1469 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEG----STALTSIPVSTT 1524 Query: 708 QPAKTSTSKAKTQP--TSLP------KQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPA 757 A + + T P TS P +PTT G + + + + G P + P Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTML 1584 Query: 758 VASARPSILPSK--DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTT--- 812 V S+ + L + D K + A +A + + GS ++ +TT Sbjct: 1585 VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVA 1644 Query: 813 ---AAAVASTGPSSRSP--------STLLPKK----PTAIKTEGKPAEVKKMTAKSVPAD 857 A+ +++T S SP S+ P + PT+ TEG+ + +T ++ P Sbjct: 1645 SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR-TPLTSITVRTTPVA 1703 Query: 858 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 917 S + ST+ + +T ++ T+ A P+ + T MP+ +TP P ++ P STT Sbjct: 1704 SSAISTLSTTPVDNSTPVT-TSTEARSSPTTSEGTSMPN---STPSEGTTPLTSIPVSTT 1759 Query: 918 PRLSRLATNTSAPDLKNVRSKVGSTE 943 P LS A+ SA + STE Sbjct: 1760 PVLSSEASTLSATPIDTSTPVTTSTE 1785 Score = 78.6 bits (192), Expect = 3e-14 Identities = 165/730 (22%), Positives = 261/730 (35%), Gaps = 101/730 (13%) Query: 324 TETDVSS----AKNVVLPTETEV---APAKDVTLLKETERASPIKMDLAPSKDMGPPKEN 376 T T+VSS A+ +PT T P +T+ +S I D P Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723 Query: 377 KKETERASPIKMD------LAPSKDMGP----PKENKIVPAKDLVLLSEIEVAQANDIIS 426 E R+SP + PS+ P P V + + LS + + + + Sbjct: 1724 STEA-RSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782 Query: 427 STEISS----AEKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAEVAPVKD 477 STE +S AE ++ + T +T P ++ ++ +A P+++ V Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTS 1842 Query: 478 MAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLP 537 A A +A ST E P+S T +A + T V V Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA-SSETNTLSTTPAVTSTPVTTY 1901 Query: 538 PEMEVALTEDQVPALKTEAPLAKDGVLT---LANNVTPAKDVPPLSETEA-TPVPIKDME 593 ++ + T ++ T P LT ++ + ++ LS T A T P+ Sbjct: 1902 AQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYS 1961 Query: 594 IAQ----TQKGISEDSHLESLQDVGQSAAP---TFMISPE--TVTGTGKKCSLPA----E 640 A T G S + S ++ P T ++S E T++ T S PA E Sbjct: 1962 QASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021 Query: 641 EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK 700 S G S PSE ++ +G+ P VVS GN ++T P + K Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGM--PVSTTLVVSSEGNTLSTTP-------VDSK 2072 Query: 701 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760 T+ +T+ + ++T++ + S P + +P L P+S P A Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPL----LTSIPLSTTPVASPEASTLSTTPVD 2128 Query: 761 ARPSILPSKDVKPKPIA------DAKAPEKRASP--SKPASAPASRSGSKSTQTVAKTTT 812 + ++ S +V PI R +P S P S S + ST + T Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188 Query: 813 AAAVASTGPSSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLS 859 + V ++ + SP+T PT+ +EG + T + P D S Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS 2248 Query: 860 RPKSTSTSSMKKTTTLSGTA-PAAGVVPSRVKATPMP-----------SRPSTTPFIDKK 907 P +TST + TT GT+ P + + T +P S STTP Sbjct: 2249 TPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNT 2308 Query: 908 P--TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAT 965 P TS + SS P A TS P S G+T + P +T +T Sbjct: 2309 PFTTSTEASSPPP----TAEGTSMP---TSTSSEGNTP-LTRMPVSTTMVASFETSTLST 2360 Query: 966 TRKPESNAVT 975 T S VT Sbjct: 2361 TPADTSTPVT 2370 Score = 78.2 bits (191), Expect = 4e-14 Identities = 205/996 (20%), Positives = 339/996 (34%), Gaps = 125/996 (12%) Query: 114 PNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLK 173 P S P+ TN P T K+ + + L P + +I A + Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPAST--MKVASSEAITLLTTPVEISTPVTISAQASSSPT 258 Query: 174 DSYGMSPCNTAVVPQGWSVEALNSPHSESFV-SPEAVAEPPQPTAVPLELAKEIEMASEE 232 + G S N+A P G S P S V S EA P A + + E AS Sbjct: 259 TAEGPSLSNSA--PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE-ASSS 315 Query: 233 RPPAQALEIMMGLKTTDMAPSKET----------EMALAKDMALATKTEV-------ALA 275 A+ I T P T EM+ + T T V +L Sbjct: 316 PTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLP 375 Query: 276 KDMESPTKLDVTLAKDMQP--SMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKN 333 E+ + L TL++ P +M LV E T + + T ++ SS+ Sbjct: 376 TTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435 Query: 334 VVLPTETEVA-PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKE----TERASPIKM 388 T + P++ T L ++ S P ++K + TE +S Sbjct: 436 TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPT 495 Query: 389 DLAPSKDMGPPKENKIVPAKDL------VLLSEIEVAQANDIISSTEISSAEKVALSSET 442 S P E P + V SE + +ST ++++ + + SS T Sbjct: 496 AEVNSMPTSTPSEGS-TPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTT 554 Query: 443 EVALARDMTLPPETNVILTK---DKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKE 499 + + P E + LT L + +E + T + + + + S+ Sbjct: 555 PEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA 614 Query: 500 VGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLA 559 G S SE G +T + ++ + A T P + + P+ Sbjct: 615 EGTSMPTSTYSER----GTTITSMSVSTTLVASSE--------ASTLSTTP-VDSNTPVT 661 Query: 560 KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAP 619 T ++ +P + TE + P+ M + T SE S L S V S Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGS-TPLTSMPVNTTLVASSEASTL-STTPVDTSTPV 719 Query: 620 TFMI----SPETVTGTGKKCSLPAEEDSVLEKLGERKPC--NSQPSELSSE--------- 664 T SP T G S P+E + L + K +S+ S LS+ Sbjct: 720 TTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHIT 779 Query: 665 -----------TSG----IARPEEGRPVVSGTG---NDITTPPNKELPPSPEKKTKPLAT 706 T G I+ P EG P+++ +T+P L +P P+ T Sbjct: 780 TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTT 839 Query: 707 TQPAKTSTSKAK--TQPTS--------LPKQPAPTT------IGGLNKKPMSLASGLVPA 750 + +S + A+ + PTS L P TT I L+ P+ ++ + + Sbjct: 840 STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNS 899 Query: 751 APPKRPAVAS---ARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKSTQT 806 + S + P+ P + P + D+ P + ++ P S +T T Sbjct: 900 TEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST 959 Query: 807 VAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTST 866 A ++ A ++ P+S P T + + A + T + P D + P +TST Sbjct: 960 EATSSPTTAEGTSIPTSTPSEGTTPLTSTPV-SHTLVANSEASTLSTTPVDSNTPLTTST 1018 Query: 867 SSMKKTTTLSGTA-----PAAGVVP-------SRVKATPMPSRPSTTPFIDKKPTS---- 910 + T GT+ P+ G P + + A+ S STTP P + Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078 Query: 911 AKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970 A SSTT + + T+T + + S ST + + T TT Sbjct: 1079 ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA 1138 Query: 971 SNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQS 1006 S++ T G G + S VS + + S Sbjct: 1139 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174 Score = 77.0 bits (188), Expect = 9e-14 Identities = 188/931 (20%), Positives = 307/931 (32%), Gaps = 163/931 (17%) Query: 156 SSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHS-ESFVSPEAVAEPPQ 214 SS T+DT P S M+P + + S P S E SP Sbjct: 96 SSVTSDT--------PGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDV 147 Query: 215 PTAVPLELAKEIEMASEERPPAQALEIMMGLK-TTDMAPSKETEMALAKDMALATKTEVA 273 P + P E + MA P + E L DM+ T + T + Sbjct: 148 PMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIP 207 Query: 274 LAKDMESPTKLDVTLAKDMQ-PSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAK 332 + + E T L A M+ S E+ L +E+ T ++ PT + S Sbjct: 208 KSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSS-PTTAEGPSLS 266 Query: 333 NVV----------LPTETEVAPAKDVTLLKETERASPIKM------DLAPSKDMGPPKEN 376 N +P + + + + L T A+ I + +P+ G Sbjct: 267 NSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPT 326 Query: 377 KKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISS---- 432 TE ++P+ P V ++ LS V + + +STE SS Sbjct: 327 STYTEGSTPLT---------STPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTT 377 Query: 433 AEKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAE--VAPVKDMAQLP--- 482 AE ++ + T + +T P + +++ +A +P++++ V + + P Sbjct: 378 AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA 437 Query: 483 -ETEIA---PAKDVAPSTV----------KEVGLLKDMSPLSETEMALGKDVTPPPETEV 528 +T IA P++ P T E L S+T++ + + P T Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE 497 Query: 529 VLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP-- 586 V P E LT V + + A T + TP S + TP Sbjct: 498 VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEG 557 Query: 587 ------------VPIKDMEI-----------------AQTQKGISEDSHLESLQDVGQSA 617 P+ +M + A + ++ S S + Sbjct: 558 TSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGT 617 Query: 618 A-PTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRP 676 + PT S T T S S L ++ P S+E + + EG Sbjct: 618 SMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTS 677 Query: 677 VVSGTGNDITTP-----PNKELPPSPEKKT---KPLATTQPAKTSTSKAKT--------Q 720 + + T + +TP N L S E T P+ T+ P TST + + Sbjct: 678 MPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASM 737 Query: 721 PTSLPKQPA-PTTIGGLNKKPMSLASGLVPAAPPKRPAV-------ASARPS-------- 764 PTS P + + P T ++K ++ + + P + AS P+ Sbjct: 738 PTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP 797 Query: 765 ---------ILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA 815 +L S V P+ +A +P S + + S+ T A+ T+ Sbjct: 798 ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT 857 Query: 816 VASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 875 ST R+P T +P T + T T + P D S P + ST + TT Sbjct: 858 --STYSEGRTPLTSMPVSTTLVATSAIS------TLSTTPVDTSTPVTNSTEARSSPTTS 909 Query: 876 SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNV 935 GT S P++TP P ++ P STTP +S A SA + Sbjct: 910 EGT-----------------SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTS 952 Query: 936 RSKVGSTENIKHQPGGGRAKVEKKTEAAATT 966 STE + T + TT Sbjct: 953 TPVTTSTEATSSPTTAEGTSIPTSTPSEGTT 983 Score = 69.3 bits (168), Expect = 2e-11 Identities = 169/793 (21%), Positives = 279/793 (35%), Gaps = 95/793 (11%) Query: 204 VSPEA--VAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALA 261 VS EA ++ P T+ P + E A+ A+ + I + P K ++ Sbjct: 1409 VSSEASTLSATPVDTSTPGTTSAE---ATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNT 1465 Query: 262 KDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR 321 T D SP ++ P+ + +A+ P+E AL + Sbjct: 1466 PVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI----STPSEGSTALTS-IP 1520 Query: 322 WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETE 381 T T SS N + T PA T + +AS +P+ G + +E Sbjct: 1521 VSTTTVASSEINSLSTT-----PAVTSTPVTTYSQASS-----SPTTADGTSMQTSTYSE 1570 Query: 382 RASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSE 441 ++P+ P +V + + LS + + +STE SS+ SS Sbjct: 1571 GSTPLT---------SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSM 1621 Query: 442 TEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVG 501 T ++ P E + +LT ++P+ + + L T + V ST EV Sbjct: 1622 T-------ISTPSEGSPLLT---SIPVSTTPVASPEASTLSTTPVDSNSPVITST--EVS 1669 Query: 502 LLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPA-------LKT 554 SP ++ T + I P T P T Sbjct: 1670 ----SSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTST 1725 Query: 555 EA---PLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQ 611 EA P +G T N TP++ PL+ + P+ E A T D+ Sbjct: 1726 EARSSPTTSEG--TSMPNSTPSEGTTPLTSIPVSTTPVLSSE-ASTLSATPIDTSTPVTT 1782 Query: 612 DVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARP 671 +++PT T T + P V L NS+ S LS+ P Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTL----VANSEASTLSTTPVDSNSP 1838 Query: 672 EEGRPVVSGT-----GNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP--TSL 724 VS + G I T E S + P++TT A + T+ T P TS Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATSTPSE--GSTALTSIPVSTTTVASSETNTLSTTPAVTST 1896 Query: 725 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784 P TT ++ P + +P + P+ RP L S V +A ++ Sbjct: 1897 PV----TTYAQVSSSPTTADGSSMPTSTPRE-----GRPP-LTSIPVSTTTVASSEINTL 1946 Query: 785 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 844 + + + + S + S+ T A T+ A + S+ P T +P T + + Sbjct: 1947 STTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGST--PLTSMPLSTTLVVSS---- 2000 Query: 845 EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI 904 + T + P D S P +TST TT GT+ PS + TP+ P +T + Sbjct: 2001 --EASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS-TPSE-RTTPLAGMPVSTTLV 2056 Query: 905 DKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAA 964 + STTP S+ T++ + + + GS+ I P G + + Sbjct: 2057 --VSSEGNTLSTTPVDSKTQV-TNSTEASSSATAEGSSMTIS-APSEGSPLLTSIPLSTT 2112 Query: 965 TTRKPESNAVTKT 977 PE++ ++ T Sbjct: 2113 PVASPEASTLSTT 2125 Score = 69.3 bits (168), Expect = 2e-11 Identities = 186/822 (22%), Positives = 285/822 (34%), Gaps = 134/822 (16%) Query: 205 SPEAVAEPP--QPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAK 262 S EA + PP + T++P + E P + + T P+ + Sbjct: 2313 STEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372 Query: 263 DMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRW 322 A ++ T A D PT + + S M +V E T + Sbjct: 2373 SQAGSSPTT---ADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS-EASTHSTTPVDTSTPV 2428 Query: 323 PTETDVSSAKNVVLPTETEVAPAKDVTLLKETERAS-PIKMDLAPSKDMGPPKENKKETE 381 T T+ SS+ T +P + T T AS P+ S + G +T Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGT----TPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484 Query: 382 RASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSE 441 + + S E+ +VP + SE + +S+T ++S E LS Sbjct: 2485 TPMTTSTEASSSPTTA---EDIVVP---ISTASEGSTLLTSIPVSTTPVASPEASTLS-- 2536 Query: 442 TEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVG 501 T P ++N + + A A M +E + P + K + Sbjct: 2537 ---------TTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587 Query: 502 LLKDMSPLSETEMALGKDVTPPPETEV--VLIKNVCLP----PEMEVALTE---DQVPAL 552 + S LS T + VT ET K+ +P E+ +LT +P Sbjct: 2588 S-SEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646 Query: 553 KTEAPLAKDGVL---TLANNVTPAKDVPPLSETEATPV--------PIKDMEIAQTQKGI 601 +EA + TL T P +E + P P+ ++ ++ T Sbjct: 2647 SSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN 2706 Query: 602 SEDSHLESLQDVGQSAAPTFMI----SPETVTGTGKKCSLPAEEDSVLEKL--------- 648 SE S L S V S T SP T GT + S P++ + L + Sbjct: 2707 SEASTL-STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVAS 2765 Query: 649 ------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK 702 S P S+E S E + + T ++ +TP L P T Sbjct: 2766 SEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTP----LTSMPVNHT- 2820 Query: 703 PLATTQPAKTSTSKAKTQP---TSLPKQPAPTTIGGLNKKPMSLASG---LVPAAPPKRP 756 P+A+++ ST+ T TS +PTT G+ P+S AS L+ + P Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGI-VVPISTASEGSTLLTSIPVSTT 2879 Query: 757 AVASARPSILPSKDVKPK-PIADA----KAPEKRASPSKPASAPA--------------- 796 VAS+ S L + V P+ + +P S P S P+ Sbjct: 2880 PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP 2939 Query: 797 ---SRSGSKSTQTVAKTT--TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM-- 849 S + + ST V T T +A AS+ P++ +++ P +T V M Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV 2999 Query: 850 ------TAKSVPADLSRPKSTSTSSMKKTTTLSGT-----APAAGVVP-------SRVKA 891 T PAD S P +TST + TT GT P+ G P + A Sbjct: 3000 ASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059 Query: 892 TPMPSRPSTTPFIDKKP--TSAKPSST-TPRLSRLATNTSAP 930 P S STTP P TS + SS+ TP A TS P Sbjct: 3060 IPEASTLSTTPVDSNSPVVTSTEVSSSPTP-----AEGTSMP 3096 Score = 66.2 bits (160), Expect = 2e-10 Identities = 160/804 (19%), Positives = 273/804 (33%), Gaps = 109/804 (13%) Query: 200 SESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTT--DMAPSKETE 257 +E+ +SP PT+ P E + P + E+ L TT D T Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT-LSTTPVDSNTLVTTS 3433 Query: 258 MALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALV 317 + +A T + + E T L + + P S+ + + + T V Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSI-MPLSTTPVASSEASTLSTTPVDTSTPVTTS 3492 Query: 318 KDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENK 377 PT + ++A+ +PT T + +T + + +P+ A + P N Sbjct: 3493 S----PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS--TTPVASSEASTLSTTPVDSNT 3546 Query: 378 KETERA----SPIKMDLAPSKDMGPPKENK-----------IVPAKDLVLLSEIEVAQAN 422 T + SP + + + M P E V + + S V ++ Sbjct: 3547 FVTSSSQASSSPATLQVTTMR-MSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRST 3605 Query: 423 DIISSTEISSA----EKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAEVA 473 + +ST+ +S E + L T ++ +T+ P + +T +A LP++ Sbjct: 3606 PVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTST- 3664 Query: 474 PVKDMAQLPETEIAPAKDVAPS-TVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK 532 PV Q+ + + P P T E P+S T + + T + V Sbjct: 3665 PVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTP 3724 Query: 533 NVCLPPEMEVALTEDQVPALKTEAPLAKDGV-LTLANNVTPAKDVPPLSETEATPVPIKD 591 + + T D + P+ + T+ + TP P S T + P Sbjct: 3725 VTTSTEAISSSATLDST-TMSVSMPMEISTLGTTILVSTTPVTRFPE-SSTPSIPSVYTS 3782 Query: 592 MEIAQTQKGISEDSHLESLQDVGQSAAP-------TFMISPETVTGTGKKCSLPAEEDSV 644 M + +G S + LE + S T +ISP +V P+E ++ Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMS-------PSEASTL 3835 Query: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP- 703 G+ S P S++ + P E + ++ +TP L + + P Sbjct: 3836 STPPGD----TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPG 3891 Query: 704 --LATTQPAKTSTS-KAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760 +A+T P TST+ T S P P TTI S + + P Sbjct: 3892 ASIASTPPLDTSTTFTPSTDTASTPTIPVATTIS---------VSVITEGSTPGTTIFIP 3942 Query: 761 ARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 820 + P + DV P + +G+ ST + T S+ Sbjct: 3943 STPVTSSTADVFP-----------------------ATTGAVSTPVITSTELNTPSTSSS 3979 Query: 821 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT--LSGT 878 ++ S ST A+ T V TA S P SR +TS S++ T+T S + Sbjct: 3980 STTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039 Query: 879 APAAGVVPSRVKATPM------------PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATN 926 V PS + P P+ ST P T+ P + T +R + Sbjct: 4040 VTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPS 4099 Query: 927 TSAPDLKNV-RSKVGSTENIKHQP 949 T V + V + IK P Sbjct: 4100 TRTTSFPTVTTTAVPTNTTIKSNP 4123 Score = 63.2 bits (152), Expect = 1e-09 Identities = 91/406 (22%), Positives = 158/406 (38%), Gaps = 44/406 (10%) Query: 572 PAKDVPPLSETEATPVPIKDMEIAQ-TQKGISEDSHLESLQDVGQSAAPTFMISPETVTG 630 P++ P L+ + P+ E + + + +S + + +V S PT S +T T Sbjct: 2097 PSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTY 2156 Query: 631 TGKKC---SLPAEE----DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 + ++ S+P S + L S P S+E EG + + T + Sbjct: 2157 SDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPS 2216 Query: 684 DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP---TSLPKQPAPTTIGGLNKKP 740 + +TP +P S T P+ T++ + S + T TS +PTT G + Sbjct: 2217 EGSTPFTS-MPVS----TMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 2271 Query: 741 MSLASGLVP--AAPPKRPAVASARPSILPSKDV-------------KPKPIADAKA-PEK 784 +L+ G P + P VA++ S L + V P P A+ + P Sbjct: 2272 STLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTS 2331 Query: 785 RASPSK------PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAI 837 +S P S S ST + T+ V + + SP+T PT+ Sbjct: 2332 TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391 Query: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897 +EG + + ++P S + ST+ + +T ++ T+ A P+ + T +P+ Sbjct: 2392 YSEGS-TPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVT-TSTEASSSPTTAEGTSIPTS 2449 Query: 898 PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943 P P P ++ P STTP +S A S + STE Sbjct: 2450 P---PSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE 2492 Score = 53.9 bits (128), Expect = 9e-07 Identities = 144/780 (18%), Positives = 262/780 (33%), Gaps = 84/780 (10%) Query: 135 PIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEA 194 P+ T P + L+ S+ TS A + + + + T+ S+ Sbjct: 3405 PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMP 3464 Query: 195 LNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSK 254 L++ +P A +E + P++ + + +S E+ T M S Sbjct: 3465 LST-------TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV------TSMPTST 3511 Query: 255 ETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEV 314 E + + T VA ++ T ++S+ + + + Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTT-----------PVDSNTFVTSSSQASSSPAT 3560 Query: 315 ALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVT-LLKETERASPIKMDLAPSKDMGPP 373 V +R T ++ SS+ +L + T V ++ T +R++P+ + PP Sbjct: 3561 LQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620 Query: 374 KENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSA 433 + S + L P V + S + V + +I+ST++SS+ Sbjct: 3621 EVITLPMSTPSEVSTPLTIM-----PVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS 3675 Query: 434 ----EKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489 E + T + +T P + +T + L + V TE + Sbjct: 3676 PVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTP-SVVTSTPVTTSTEAISS 3734 Query: 490 KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQV 549 ST V + ++S L T + VT PE+ I +V M A Sbjct: 3735 SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS 3794 Query: 550 PAL---KTEAPLA---KDGVLTLANNVTPAKDVPPLSETEATPVPIKDME---IAQTQKG 600 P T P++ + L ++P + P SE P D + T+ G Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSP-SEASTLSTPPGDTSTPLLTSTKAG 3853 Query: 601 ---ISEDSHLESLQDVGQSAAP--TFMIS---PETVTGTGKKCSLPAEEDSVLEKLGERK 652 I + + + + P T ++S P + G + P + + + Sbjct: 3854 SFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTA 3913 Query: 653 PCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKT 712 + P + S I + +T+ P + + P+ T+ T Sbjct: 3914 STPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNT 3973 Query: 713 STSKAKTQPTSLPKQ-----PAPTTIGGLNKKPMSLASGLVPAAP---------PKRPAV 758 ++ + + TS PA TT L MS A P+ P Sbjct: 3974 PSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTA----PSTPRTTSRGCTTSASTLS 4029 Query: 759 ASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVA 817 A++ P S +P P +++ P S + P + P + S + T + + TT Sbjct: 4030 ATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAV 4089 Query: 818 STGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSG 877 +T + PST PT T A T KS P TST ++ +TTT G Sbjct: 4090 TTMTTRTKPSTRTTSFPTVTTT----AVPTNTTIKSNP--------TSTPTVPRTTTCFG 4137 >gi|38261962 activating transcription factor 7 interacting protein [Homo sapiens] Length = 1270 Score = 86.7 bits (213), Expect = 1e-16 Identities = 171/762 (22%), Positives = 274/762 (35%), Gaps = 91/762 (11%) Query: 285 DVTLAKDMQPSMESDMA--LVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEV 342 D T+ D P E + ++ ++ L + + ++ + D +SA V E + Sbjct: 356 DTTICSDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVI 415 Query: 343 APAKDVTLLK-----ETERASPIKMDLAPSKD---------------MGPPKENKKETER 382 K +L+ ET+ PI LAPS+D P E K E+ Sbjct: 416 EDNKSENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSF 475 Query: 383 ASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSE---IEVAQANDIISSTEISSAEKVALS 439 SP K + + S PKE +V + + + E EV N+ S E+ S EK Sbjct: 476 GSPSKQESSESL----PKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKP 531 Query: 440 SETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPE-------TEIAPAKDV 492 E E + D P E N + ++ + + K + E +I D+ Sbjct: 532 EEEEQVIHEDDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDI 591 Query: 493 APSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ--VP 550 K + L + L + A+ +T V I+ + LTE Q + Sbjct: 592 NQKLQKVIQWLLE-EKLCALQCAVFDKTLAELKTRVEKIE---CNKRHKTVLTELQAKIA 647 Query: 551 ALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESL 610 L AK+ L + P PP+S + + ++ G LES Sbjct: 648 RLTKRFEAAKED-LKKRHEHPPN---PPVSPGKTVNDVNSNNNMSYRNAGTVRQM-LESK 702 Query: 611 QDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIAR 670 ++V +SA P+F TV+ T + PA S + K S + TS + Sbjct: 703 RNVSESAPPSFQTPVNTVSSTNL-VTPPAVVSS------QPKLQTPVTSGSLTATSVLPA 755 Query: 671 PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--- 727 P V + P L P P P+A + + S T T+ P Sbjct: 756 PNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVE 815 Query: 728 ----PAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783 +P T+ GL K P+SL S P P P+V S PSI + P+ A + Sbjct: 816 FISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPS--PSIQRNPTASAAPLGTTLAVQ 873 Query: 784 KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGP-SSRSPSTLLPKKPTAIKTEGK 842 A P+ + A+R+ S TV + + + GP + P + A + Sbjct: 874 --AVPTAHSIVQATRT---SLPTVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNT 928 Query: 843 PAEVKKMTAKSVPADLSRPKSTSTSSMKKTT----------TLSGTAPAAGVVPSRVKAT 892 ++ T K++ A +S+ + STS K T T+ A P ++ T Sbjct: 929 TPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHT 988 Query: 893 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVR--SKVGSTENIKHQPG 950 P+ + S+ P +P +P P L TS P + +T N+ H+P Sbjct: 989 PVSTMSSSQPV--SRP--LQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRP- 1043 Query: 951 GGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKV 992 V + T R P ++ V T P AQ G V Sbjct: 1044 -----VTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV 1080 Score = 31.2 bits (69), Expect = 5.9 Identities = 114/607 (18%), Positives = 193/607 (31%), Gaps = 105/607 (17%) Query: 374 KENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDL-----VLLSEIEVAQANDIISST 428 KE+ K+ P ++P K + N + ++ +L S+ V+++ T Sbjct: 657 KEDLKKRHEHPP-NPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQT 715 Query: 429 EISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAP 488 +++ L + V ++ P T+ LT LP A V Q+P P Sbjct: 716 PVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAP-NTATVVATTQVPSGNPQP 774 Query: 489 AKDVAPSTV----------------KEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK 532 + P V G L P E V PP T L K Sbjct: 775 TISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFI---SVQSPP-TVSGLTK 830 Query: 533 NVCLPPEMEVALTEDQVPALKTEA----PLAKDGVL--TLANNVTP-AKDVPPLSETEAT 585 N P + + VP++ + + P A L TLA P A + + T Sbjct: 831 NPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLP 890 Query: 586 PVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVL 645 V + T +G + S +A +P T K + + Sbjct: 891 TVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAAD 950 Query: 646 EKLGERKPCNSQPS-----ELSSETSGIARPEEG---RPVVSGTGNDITTPPNKELPPSP 697 K S S + E SG ++ + PV + + + + P + + P+P Sbjct: 951 STSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAP 1010 Query: 698 EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL-VPAAPPKRP 756 + + T+ P++T+ T APTT+ ++ + + L VP AP Sbjct: 1011 PLQPSGVPTSGPSQTTIHLLPT---------APTTVNVTHRPVTQVTTRLPVPRAPANHQ 1061 Query: 757 AVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAV 816 V + P+ A+AP + PA + S + + V +TTT Sbjct: 1062 VVYTTLPA------------PPAQAPLRGTVMQAPAVRQVNPQNSVTVR-VPQTTTYVVN 1108 Query: 817 ASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL- 875 S P + +P + TE P V P P +++S+ + L Sbjct: 1109 NGLTLGSTGPQLTVHHRPPQVHTE-PPRPVHPAPLPEAPQPQRLPPEAASTSLPQKPHLK 1167 Query: 876 --------------------------------------SGTAPAAGVVPSRVKATPMPSR 897 S T P+ VKA P+P Sbjct: 1168 LARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVPSQWKKIGEVKALPLPMA 1227 Query: 898 PSTTPFI 904 + T F+ Sbjct: 1228 CTLTQFV 1234 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 82.8 bits (203), Expect = 2e-15 Identities = 145/624 (23%), Positives = 230/624 (36%), Gaps = 72/624 (11%) Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEI-EMASEERPPAQALEIMMGLKTTDM 250 ++ + E+ + E E V E KE E +E + E G + T Sbjct: 444 IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKS 503 Query: 251 APSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310 P++E K+ K E + +SP K + +++ ++ ++ + P Sbjct: 504 PPAEEAASP-EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562 Query: 311 EKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERA-SPIKMDL-APSK 368 E + ++ + P E V S + P + E AK K E+A SP+K + +P++ Sbjct: 563 EAKSPEKEEAKSPAE--VKSPEKAKSPAKEE---AKSPAEAKSPEKAKSPVKEEAKSPAE 617 Query: 369 DMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISS- 427 P KE K SP ++ +P K P KE P K E E A++ + S Sbjct: 618 AKSPVKEEAK-----SPAEVK-SPEKAKSPTKEEAKSPEK--AKSPEKEEAKSPEKAKSP 669 Query: 428 --TEISSAEKV-------ALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDM 478 E S EK A S E + ++ PE K++A E +PVK+ Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729 Query: 479 AQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPP 538 A+ PE +P K+ A S K SP + + P E P Sbjct: 730 AKTPEKAKSPVKEEAKSPEKA------KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783 Query: 539 EMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ 598 + + + E+ K ++PL +D P K++P E ++ P+K+ E Q Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAK-------APEKEIPKKEEVKS---PVKEEEKPQEV 833 Query: 599 KGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERK-PCNSQ 657 K E + AP +P+T K ++++ K+ E+K P + Sbjct: 834 KVKEPPKKAE------EEKAPA---TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884 Query: 658 PSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK--TKPLATTQPAKTSTS 715 P E E A+ EE P KE P E K KP T+ AK Sbjct: 885 PKESKVE----AKKEEAEDKKK------VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934 Query: 716 KAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKP 775 AK + P +PA KK P PK A A L + KPK Sbjct: 935 DAKAKE---PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK- 990 Query: 776 IADAKAPEKRASPSKPASAPASRS 799 A+ EK +S + S P ++ Sbjct: 991 ---AEKAEKSSSTDQKDSKPPEKA 1011 Score = 81.6 bits (200), Expect = 4e-15 Identities = 129/574 (22%), Positives = 213/574 (37%), Gaps = 85/574 (14%) Query: 294 PSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKE 353 P E+ + ++ + P E + ++ + P E V S + P + E + ++ Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE--VKSPEKAKSPAKEEAKSPPEAKSPEK 569 Query: 354 TERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLL 413 E SP ++ +P K P KE K A +P K P KE PA Sbjct: 570 EEAKSPAEVK-SPEKAKSPAKEEAKSPAEAK------SPEKAKSPVKEEAKSPA------ 616 Query: 414 SEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKAL-PLEAEV 472 E + + S E+ S EK A S E A + + PE + +KA P++AE Sbjct: 617 -EAKSPVKEEAKSPAEVKSPEK-AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674 Query: 473 -------APVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPE 525 +PVK A+ PE +P K+ A S K +K+ + E + K+ PE Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734 Query: 526 TEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDV---PPLSET 582 +K PE A + ++ L ++P AK TPAK+ P Sbjct: 735 KAKSPVKEEAKSPEK--AKSPEKAKTLDVKSPEAK----------TPAKEEARSPADKFP 782 Query: 583 EATPVPIKDMEIAQTQKG---ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPA 639 E P+K+ E+ +K + ED+ +PE ++ P Sbjct: 783 EKAKSPVKE-EVKSPEKAKSPLKEDAK-----------------APEKEIPKKEEVKSPV 824 Query: 640 EEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP-PSPE 698 +E+ +++ ++P E + T ++ + + P KE P P E Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA---------PKKEAPKPKVE 875 Query: 699 KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV 758 +K +P A +P ++ K + K P P K+ + A P ++ V Sbjct: 876 EKKEP-AVEKPKESKVEAKKEEAEDKKKVPTP------EKEAPAKVEVKEDAKPKEKTEV 928 Query: 759 ASARPSIL----PSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK-STQTVAKTTTA 813 A P PSK + K A K K KP P + + +K +T++K + Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK 988 Query: 814 AAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847 SS + KP TE K A+ K Sbjct: 989 PKAEKAEKSSSTDQK--DSKPPEKATEDKAAKGK 1020 Score = 69.7 bits (169), Expect = 2e-11 Identities = 126/567 (22%), Positives = 195/567 (34%), Gaps = 93/567 (16%) Query: 339 ETEVAPAKDVTLLKETERASPIKMDL-APSKDMGPPKENKKETERASPIKMDLAPSKDMG 397 ET+ PA++ E E SP+K + +P++ P KE K SP ++ +P K Sbjct: 500 ETKSPPAEEAAS-PEKEAKSPVKEEAKSPAEAKSPEKEEAK-----SPAEVK-SPEKAKS 552 Query: 398 PPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN 457 P KE P E + + + S E+ S EK ++ E + P + Sbjct: 553 PAKEEAKSPP-------EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605 Query: 458 VILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALG 517 + ++ P EA+ +PVK+ A+ P +P K +P+ + K SP E E Sbjct: 606 SPVKEEAKSPAEAK-SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE-EAKSP 663 Query: 518 KDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNV-TPAKDV 576 + P + E + P + E E +K EA + + +P K Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723 Query: 577 PPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCS 636 P+ E TP K + E++ + A + SPE T Sbjct: 724 SPVKEEAKTPEKAKSP--------VKEEAKSPEKAKSPEKAKTLDVKSPEAKT------- 768 Query: 637 LPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPS 696 PA+E++ R P + P + S P KE S Sbjct: 769 -PAKEEA-------RSPADKFPEKAKS-------------------------PVKEEVKS 795 Query: 697 PEKKTKPLATTQPA-------------------KTSTSKAKTQPTSLPKQPAPTTIGGLN 737 PEK PL A K K K P ++ AP T Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855 Query: 738 KKPMSLASGLVPAAP------PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 KK AP K PAV + S + +K + + PEK A P+K Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA-PAKV 914 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851 ++ K+ + A A + P+ + + KK T + KP E K A Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA-PEKKDTKEEKAKKPEEKPKTEA 973 Query: 852 KSVPADLSRPKSTSTSSMKKTTTLSGT 878 K+ D + K S +K S T Sbjct: 974 KAKEDDKTLSKEPSKPKAEKAEKSSST 1000 Score = 66.6 bits (161), Expect = 1e-10 Identities = 101/474 (21%), Positives = 171/474 (36%), Gaps = 53/474 (11%) Query: 640 EEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEK 699 EE V E++ E + ++ E E G EG G + T P E SPEK Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG-------GEEETKSPPAEEAASPEK 514 Query: 700 KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVA 759 + K + + S ++AK+ K PA K P S P + Sbjct: 515 EAK--SPVKEEAKSPAEAKSPEKEEAKSPAEV------KSPEKAKS-------PAKEEAK 559 Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKP-ASAPASRSGSKSTQTVAKTTTAAAVAS 818 S + P K+ P A+ K+PEK SP+K A +PA + ++ K A Sbjct: 560 SPPEAKSPEKEEAKSP-AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE-----AK 613 Query: 819 TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 878 + ++SP K P +K+ K K AKS S K + S K + + Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673 Query: 879 APAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 938 A + S VKA + +P ++ + K S ++ +P + ++ Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733 Query: 939 VGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKK 998 + +K + + + PE+ P + PA K +K Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------PAKEEARSPADKFPEKAKS 787 Query: 999 VSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKI-E 1057 ++S +K +K ++ K ++ K K+ +K + +VK+ E Sbjct: 788 PVKEEVKSPEKAKSPLK----------EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837 Query: 1058 SQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISE 1111 K +EKA A + + + K E EAP P +EPA+ + Sbjct: 838 PPKKAEEEKAPATPKTEEK------KDSKKEEAPKKEAPK-PKVEEKKEPAVEK 884 Score = 55.5 bits (132), Expect = 3e-07 Identities = 81/331 (24%), Positives = 133/331 (40%), Gaps = 41/331 (12%) Query: 191 SVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDM 250 S E SP E SPE P + A E AK A + P + K+ + Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693 Query: 251 APSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310 A S E A + + A +SP K + + + ++ + + + P Sbjct: 694 AKSPVKEEAKSPEKA-------------KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740 Query: 311 EKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDM 370 ++E + + P AK + + + PAK+ E SP D P K Sbjct: 741 KEEAKSPEKAKSP-----EKAKTLDVKSPEAKTPAKE-------EARSP--ADKFPEKAK 786 Query: 371 GPPKENKKETERA-SPIKMDL-APSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISST 428 P KE K E+A SP+K D AP K++ P KE P K+ E++V + Sbjct: 787 SPVKEEVKSPEKAKSPLKEDAKAPEKEI-PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845 Query: 429 EISSAEKV--ALSSETEVALARDMTLPPETNVILTKDKAL--PLEAEVAPVKDMAQLPET 484 + + K S+ E A ++ P+ V K+ A+ P E++V K+ A+ + Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKE---APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902 Query: 485 EIAPAKDVAPSTVKEVGLLKDMSPLSETEMA 515 P K+ AP+ V+ + +D P +TE+A Sbjct: 903 VPTPEKE-APAKVE---VKEDAKPKEKTEVA 929 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 80.5 bits (197), Expect = 9e-15 Identities = 186/873 (21%), Positives = 289/873 (33%), Gaps = 150/873 (17%) Query: 235 PAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQP 294 PA + + D PS + + + +L T +L SPT +L P Sbjct: 368 PATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL-----SPT---TSLILKSSP 419 Query: 295 SMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET 354 + LV M + + LV +++A T V+P + Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVT----NPCTIAAAPTTTFEVATCVSPPMSSGPISNI 475 Query: 355 ERASPIKMDLAPSKD--------------MGPPKENKKETERA-SPIKMDLAPSKDMGP- 398 E SP + +AP + PP + ++ + S + + KD+ Sbjct: 476 EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV 535 Query: 399 ----------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL-- 446 P + + KD +L ++ A N S SS+ ++ LS E +A Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP-SFQSTSSSPEIPLSPEATLAKKS 594 Query: 447 ----------ARDMTLPPETN----VILTK-----DKALPLEAEVAPVKDMAQLPETEIA 487 A MT P N VI T D A PL +A P Sbjct: 595 LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654 Query: 488 PAKDVAPSTVKEVGLLKDM-SPLSETEMALGKD-----------------------VTPP 523 PA VAP+T K SP E ++L V P Sbjct: 655 PA-GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPS 713 Query: 524 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 583 P+ + + L PE+ ++ +P T K ++ + + P P TE Sbjct: 714 PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773 Query: 584 AT------------------PVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMIS- 624 + P P+ QT++ ++ +G ++P + Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833 Query: 625 ---PE-TVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSG 680 PE +++ G K S PA S + P S + LS + G+ P + P Sbjct: 834 SFLPENSLSFQGSKDS-PATTHSPTPPSPKGAPTPSAVTPLSPK--GVTLPPKETP---- 886 Query: 681 TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 740 T + + P KE P +P K P + + ++A P +P P+P K Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP--------KG 938 Query: 741 MSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG 800 P +P PA S + + P P P P + +P+ PA+ P S G Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998 Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPK----KPTAIKTEGKPAEVKKMTAKSVP- 855 +T + T AV P +T PK P A K + K P Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058 Query: 856 ---ADLSRPK-STSTSSMKKTTT---LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP 908 A L PK +T S+K T + +P G K PMP P+ TP K Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP--PAATPPSPKGG 1116 Query: 909 TSAKP---SSTTPRLSRLAT--NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKK---T 960 + P + TTP + + + P K + +T P GG A K T Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT---PPSPKGGLATPPPKGAPT 1173 Query: 961 EAAATTRKPESNAVTKT--AGPIASAQKQPAGK 991 AAT P+ T + P A P+ K Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206 Score = 75.1 bits (183), Expect = 4e-13 Identities = 128/553 (23%), Positives = 190/553 (34%), Gaps = 81/553 (14%) Query: 482 PETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEME 541 P P+ P+T G P + G TPPP K PP + Sbjct: 1289 PAVVTPPSPKGGPATSPPKGA--PTPPAATPPSPKGSPGTPPP-------KGAPTPPAVT 1339 Query: 542 VALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEA---TPVPIKDMEIAQTQ 598 + P L P +K G T ++ P S TP K + Sbjct: 1340 PPSPKG-TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398 Query: 599 KGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQP 658 KG D ++ + AP ++ E K P V K + P S P Sbjct: 1399 KG---DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK---KAPATSAP 1452 Query: 659 SELSSETSGIARPE-EGRPVVSGTGNDITTPPNKELPPSPEK-KTKPLATTQPAKTSTSK 716 G A P +G P + TPP+ + PP+P++ T PA + Sbjct: 1453 K------GGPATPSSKGDPTLPAV-----TPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501 Query: 717 AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 776 A T P +P P + P + +S P AP ++ P+ L K+ P Sbjct: 1502 APTLPAVIPSSP--------KEVPATPSSRRDPIAPTAT-LLSKKTPATLAPKEALIPPA 1552 Query: 777 ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST------GPSSRSPSTLL 830 +P+K + P APA+ S +++ A T + A + P+ SPS Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612 Query: 831 PKKPTAI----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG--- 883 P A+ +G K T S P S K + TS T + T P A Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672 Query: 884 ---VVPSRVKATPMPSRPSTTPFID----KKPTSAKPSSTTPRL---------SRLATNT 927 P+ +K + P +TP I K P + K S+T+P + S+ +T Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732 Query: 928 SAP----DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR-------KPESNAVTK 976 AP ++ SK ++ H P G A E K T KPES +V+ Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792 Query: 977 TAGPIASAQKQPA 989 P S P+ Sbjct: 1793 APSPPVSLPLAPS 1805 Score = 74.7 bits (182), Expect = 5e-13 Identities = 109/425 (25%), Positives = 162/425 (38%), Gaps = 60/425 (14%) Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ----PSELSSETSGIAR----PEEG 674 ++P + GT +LPA S K G P + + P+ S G A P+ G Sbjct: 1338 VTPPSPKGTP---TLPATTPS--SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392 Query: 675 RPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ----PAKTSTSKAKTQPTSLPKQPAP 730 P + D T+P +P SP+K T + P+K + P SL K PA Sbjct: 1393 -PAIPSPKGDPTSPA--VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449 Query: 731 TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK--APEKRAS- 787 + G P S +PA P P A + S K P A AP A Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509 Query: 788 PSKPASAPASRSGSKS----TQTVAKTTTAAAVAS---------TGPS-SRSPSTLLPKK 833 PS P PA+ S + T T+ T A +A T PS ++P+ PK+ Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569 Query: 834 PTAI---KTEGKPAEVKKMTAKSVPA--DLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSR 888 A K P V T K P+ +L P + ++ S K+ T P + P + Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS---PEK 1626 Query: 889 VKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL-KNVRSKVGST--ENI 945 ATP P T+P + P+S K S T+P + P K + +K G T + + Sbjct: 1627 GPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684 Query: 946 KHQPGGGRAKV----------EKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIV 995 P + KK+ A + P+ +A + GP+++ P VQ Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744 Query: 996 SKKVS 1000 S K + Sbjct: 1745 SSKTA 1749 Score = 70.5 bits (171), Expect = 9e-12 Identities = 126/550 (22%), Positives = 172/550 (31%), Gaps = 75/550 (13%) Query: 467 PLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP--- 523 P P A P P+ P+T G M P + G TPP Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA--PMPPAATPPSPKGGLATPPHKG 1124 Query: 524 -PETEVVLIKN----VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPP 578 P T + + PP T P P K G+ T P K P Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATP------PSPKGGLAT-----PPPKGAP- 1172 Query: 579 LSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLP 638 + ATP K + KG G A P+ +P T T P Sbjct: 1173 -TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-----P 1226 Query: 639 AEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG-----NDITTPPNKEL 693 + + + + P + S + P +G P + TPP+K Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286 Query: 694 PPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP 753 P +P T P PA + A T P + P P G P + PA P Sbjct: 1287 P-NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-----GSPGTPPPKGAPTPPAVTP 1340 Query: 754 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTA 813 P P+ PS P P + P+ PA+ P+ + G T K A Sbjct: 1341 PSPKGTPTLPATTPSSKGGP------TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394 Query: 814 AAVASTGPSSRSPSTLLPKK--PTAIKTEG---------KPAEVKKMTAKSVPADLSRPK 862 P+S + L PKK T + EG P V ++ K PA + Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454 Query: 863 STSTSSMKKTTTLSGTAP------------AAGVVPSRVKATPMPSRPSTTPFIDKKPTS 910 +T S K TL P A P + ATP P T P + P+S Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV--IPSS 1512 Query: 911 AKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ--PGGGRAKVEKKTEAAATTRK 968 K TP R + AP + K +T K P KKT A T ++ Sbjct: 1513 PKEVPATPSSRR---DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569 Query: 969 PESNAVTKTA 978 + +K A Sbjct: 1570 APATPSSKEA 1579 Score = 61.6 bits (148), Expect = 4e-09 Identities = 140/624 (22%), Positives = 208/624 (33%), Gaps = 98/624 (15%) Query: 335 VLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSK 394 V+P + APA VT A+P K DL P P KK ++P PS Sbjct: 1407 VIPLSPKKAPATPVT---REGAATPSKGDLTPPAVT--PVSLKKAPATSAPKGGPATPSS 1461 Query: 395 DMGP------PKENKIVPA-KDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL- 446 P P K PA K + S + A A A V SS EV Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA--VIPSSPKEVPAT 1519 Query: 447 --ARDMTLPPETNVILTKDKAL--PLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGL 502 +R + P ++ K A P EA + P + +T P AP+T Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP----- 1574 Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562 S E + VTP K + +PP + ++ P + G Sbjct: 1575 -------SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627 Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIA--------QTQKGISEDSHLESLQDVG 614 T A TP PP++ + P + Q KG+ +L++V Sbjct: 1628 PATPAPKGTPTS--PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685 Query: 615 QSAAP--TFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPE 672 + AP T +I+ T G K S + + N LS+ P Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK----NGSKGPLSTVAPAPLLPV 1741 Query: 673 EGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATT-------QPAKTSTSKAKTQPTSLP 725 + + G D + P L P K + PL +P S S A + P SLP Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801 Query: 726 KQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKR 785 P+P VP PPK+ + S+ +L S KP+A A E Sbjct: 1802 LAPSP-----------------VPTLPPKQQFLPSSPGLVLESPS---KPLAPADEDE-- 1839 Query: 786 ASPSKPASAPASRSGSKSTQTV---AKTTTAAAVASTGPSSRSPST-------------- 828 P P SG Q+V T +A + PS++ P T Sbjct: 1840 ---LLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896 Query: 829 LLPKKPTAIKTEGKPAEVKKMTAKSVPAD-LSRPK-STSTSSMKKTTTLSGTAPAAGVVP 886 +P+ T+ + + A + + +S+ K S S +K + G GV Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTR 1956 Query: 887 SRVKATPMPSRPSTTPFIDKKPTS 910 ++ + T P + K P S Sbjct: 1957 VTIRKSKNILFVITKPDVYKSPAS 1980 Score = 39.3 bits (90), Expect = 0.022 Identities = 127/516 (24%), Positives = 187/516 (36%), Gaps = 77/516 (14%) Query: 522 PPPETEVVLIKNVCLP-PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLS 580 P TE V LP P+ E A+ AL A L + G TL +PA PLS Sbjct: 2 PGEATETVPATEQELPQPQAETAVLP-MSSALSVTAALGQPGP-TLPPPCSPAPQQCPLS 59 Query: 581 ET-EATPVPIKDMEIAQTQKGIS--EDSHLESLQDVGQSAAPTFM-------ISPETV-- 628 +A+P P IA T + + S +L APTF+ ISP + Sbjct: 60 AANQASPFP-SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118 Query: 629 -------TGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGT 681 T G S L +K P+ L+S S +A E G + Sbjct: 119 ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPS-VAVAESGSVITLSA 177 Query: 682 G---NDITTPPNK---ELPPSPEKKTKP--LATTQPAKTSTSKAKTQP--TSLPKQPAPT 731 ++ T NK E+ P+P+ P + +T P T A Q SLP Q PT Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP-QTTPT 236 Query: 732 T---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILP--SKDVKPKPIADAKAPEKRA 786 T I K +++S L+ P+ P S + + P + + + + + +K A Sbjct: 237 TTLAIASPQVKDTTISSVLIS---PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293 Query: 787 SPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRS------------------PST 828 P+ P P S + + + + TGPS+ S PS Sbjct: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ 353 Query: 829 LLPKKPTAIKTEGKPAEVK--KMTAKSV---PADLSRPKSTSTSSMKKTTTLSGTAPAAG 883 P + E PA V + A SV P+ +S + + S+ T+ S + + Sbjct: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413 Query: 884 VVPSRVKAT-------PMP-SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNV 935 ++ S AT MP S TTP + P + + TT +AT S P Sbjct: 414 ILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT--TFEVATCVSPPMSSGP 471 Query: 936 RSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPES 971 S + T K E T+ A T R P S Sbjct: 472 ISNIEPTSPAALVMAPVAPK-EPSTQVATTLRIPVS 506 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 77.0 bits (188), Expect = 9e-14 Identities = 84/339 (24%), Positives = 122/339 (35%), Gaps = 35/339 (10%) Query: 653 PCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKT 712 P + PS ++ T+ P ++ T TTPP P P T TT P T Sbjct: 1417 PPTTTPSPPTTTTTTPPPTTTPSPPITTT----TTPPPTTTPSPPISTT----TTPPPTT 1468 Query: 713 STSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVK 772 + S T P+ P+P T P + P+ P P A + LP Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTT-----TPSPPTTTPITPPASTTTLPPTTTP 1523 Query: 773 PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPK 832 P P +PS P + P + ST T+ TTT + +T ++ P T P Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPP--TSTTTLPPTTTPSPPPTT--TTTPPPTTTPS 1579 Query: 833 KPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 892 PT P+ T P P +T+T++ TTT S P + T Sbjct: 1580 PPTTTT----PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS--PPTTTPITPPTSTT 1633 Query: 893 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGG 952 +P P+TTP T+ P +TTP S T T +P + + +T P Sbjct: 1634 TLP--PTTTPSPPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPPTT-----TPSSP 1684 Query: 953 RAKVEKKTEAAATTRKP---ESNAVTKTAGPIASAQKQP 988 TT P S+ +T T P ++ P Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723 Score = 68.6 bits (166), Expect = 3e-11 Identities = 106/452 (23%), Positives = 140/452 (30%), Gaps = 67/452 (14%) Query: 533 NVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDM 592 N C P M+ +T P P TL TP+ + T P + Sbjct: 1387 NCCWP--MDKCITTPSPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPI 1442 Query: 593 EIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKC--SLPAEEDSVLEKLGE 650 T + S S + PT SP T T + S P + Sbjct: 1443 TTTTTPPPTTTPSPPISTTT---TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT 1499 Query: 651 RKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPA 710 P + P + T+ + P + T TTPP P P TT P Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTT----TTPPPTTTPSPP--------TTTPI 1547 Query: 711 KTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKD 770 TS PT+ P P TT P + P P + + P P Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTT----TTPPPTTTPSPPTTTTPSPPTITTTTP---PPTT 1600 Query: 771 VKPKPIADAKAPEKRASPSKPASAPASRSGSKST--------------QTVAKTTTAAAV 816 P P +PS P + P + S +T T TTT + Sbjct: 1601 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660 Query: 817 ASTGPS--------------SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862 +T PS SP T P PT T P T S + P Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT----TTPSSPITTTTTPS 1716 Query: 863 STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 922 ST+T S TT T P+ PS T M + P TT T PS T P S Sbjct: 1717 STTTPSPPPTTM---TTPSPTTTPS-PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772 Query: 923 LATNTSAPDLKNVRSKVGSTENIK---HQPGG 951 +T T + + G ++ K H+PGG Sbjct: 1773 FSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804 Score = 57.8 bits (138), Expect = 6e-08 Identities = 74/347 (21%), Positives = 122/347 (35%), Gaps = 32/347 (9%) Query: 654 CNSQPSELSSETSGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAKT 712 C +QP+ +++ T+ P P+ + T T TP + P + T T P T Sbjct: 1878 CVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1937 Query: 713 STSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPS 768 T T P T++ P PT P++ + + P P + P I + Sbjct: 1938 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 1996 Query: 769 KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPST 828 V P P P + P + + +T T T T +T P + + + Sbjct: 1997 TTVTPTPTP--------TGTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTV 2045 Query: 829 LLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAA 882 PT +T +T P P + T+T+++ T T +GT P Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105 Query: 883 GVVPSRVKATPMPS-----RPSTTPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLK 933 + + TP P+ P+TTP + P+ T TP + + T T+ P Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165 Query: 934 NVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980 ++ +T I T+ TT + VT T P Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212 Score = 53.9 bits (128), Expect = 9e-07 Identities = 92/433 (21%), Positives = 144/433 (33%), Gaps = 56/433 (12%) Query: 565 TLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMIS 624 T N TP P + T TP P T I+ + + + PT + Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 1945 Query: 625 PETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGND 684 P T T T P G + P + + ++ T P +GT Sbjct: 1946 PITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTP--------TPTPTGTQTP 1988 Query: 685 ITTP--PNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 TTP + P+P TT P T+T+ T PT Q TT P++ Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTT-------PIT 2040 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802 + + P P + P I + V P P P + P + + Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 2088 Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 860 +T T T T +T P + + + PT +T +T P Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2148 Query: 861 PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 911 P + T+T+++ T T +GT P + + TP P+ P+TTP + Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208 Query: 912 KPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR 967 P+ T TP + + T T+ P ++ +T I T+ TT Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268 Query: 968 KPESNAVTKTAGP 980 + VT T P Sbjct: 2269 ITTTTTVTPTPTP 2281 Score = 52.4 bits (124), Expect = 2e-06 Identities = 115/562 (20%), Positives = 175/562 (31%), Gaps = 71/562 (12%) Query: 453 PPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPLSE 511 PP T I T P P Q P T I V P+ +P++ Sbjct: 1895 PPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949 Query: 512 TEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVT 571 T VTP P T P +T P T+ P +T VT Sbjct: 1950 TTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTTVT 2000 Query: 572 PAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622 P P + T TP P T I+ + + + PT Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-- 2058 Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGRPV 677 +P T T T P G + P + + ++ T +G P Sbjct: 2059 TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109 Query: 678 VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTI 733 + T TP + P + T T P T T T P T++ P PT Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169 Query: 734 GGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPAS 793 P++ + + P P + P I + V P P P + Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTT 2220 Query: 794 APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTA 851 P + + +T T T T +T P + + + PT +T +T Sbjct: 2221 TPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277 Query: 852 KSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTP 902 P P + T+T+++ T T +GT P + + TP P+ P+TTP Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337 Query: 903 FIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEK 958 + P+ T TP + + T T+ P ++ +T I Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2397 Query: 959 KTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2398 GTQTPTTTPITTTTTVTPTPTP 2419 Score = 52.4 bits (124), Expect = 2e-06 Identities = 108/527 (20%), Positives = 161/527 (30%), Gaps = 76/527 (14%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3733 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3788 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3838 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3839 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3898 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3899 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4007 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRA 786 P++ + + P P + P I + V P P P Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTT 4066 Query: 787 SPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG---PSSRSPSTLLPKKPTAIKTEGKP 843 + P P +T TT TG P++ +T PT T + Sbjct: 4067 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126 Query: 844 AEVKKMTAKSVPADLSRPKST---STSSMKKTTTLSGT-------APAAGVVPSRVKATP 893 +T + P T +T+ + TTT++ T P + + TP Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186 Query: 894 M----------PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 930 P+ ST P + ++ P S+TP+ SR +TS+P Sbjct: 4187 TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR---STSSP 4230 Score = 52.0 bits (123), Expect = 3e-06 Identities = 98/484 (20%), Positives = 152/484 (31%), Gaps = 51/484 (10%) Query: 521 TPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLS 580 TPP T + V P T P T T TP P + Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTT-TPITT 1949 Query: 581 ETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAE 640 T TP P T I+ + + + PT +P T T T P Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT- 2006 Query: 641 EDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGRPVVSGTGNDITTPPNKELPP 695 G + P + + ++ T +G P + T TP + P Sbjct: 2007 --------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2058 Query: 696 SPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASGLVPAA 751 + T T P T T T P T++ P PT P++ + + P Sbjct: 2059 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118 Query: 752 PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 811 P + P I + V P P P + P + + +T T T Sbjct: 2119 TPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT---TTVTPTPTP 2166 Query: 812 TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSRPKS---TST 866 T +T P + + + PT +T +T P P + T+T Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226 Query: 867 SSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSAKPSST---T 917 +++ T T +GT P + + TP P+ P+TTP + P+ T T Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286 Query: 918 PRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTK 976 P + + T T+ P ++ +T I T+ TT + VT Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346 Query: 977 TAGP 980 T P Sbjct: 2347 TPTP 2350 Score = 51.2 bits (121), Expect = 6e-06 Identities = 82/398 (20%), Positives = 115/398 (28%), Gaps = 39/398 (9%) Query: 461 TKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDV 520 T LP +P P P+ + +T P + + Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP--------PTTTPSPPISTTT 1462 Query: 521 TPPPETEVVLIKNVCLPPEMEVA---LTEDQVPALKTEAPLAKDGVLTLANNVT--PAKD 575 TPPP T PP + T P T +P + A+ T P Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522 Query: 576 VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKC 635 P + T TP P T S S PT +P T Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582 Query: 636 SLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGR-----PVVSGTGNDITT--- 687 + ++ S P+ ++ P P S T TT Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642 Query: 688 -PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASG 746 PP P P P TT P+ T+ PT+ P P TT P + + Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT----PSPPTTTMTT 1698 Query: 747 LVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 806 P P P + PS S P P +PS P + + T Sbjct: 1699 PSPTTTPSSPITTTTTPS---STTTPSPPPTTMTTPSPTTTPSPPTT---------TMTT 1746 Query: 807 VAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKP 843 + TTT++ + +T P S +P T P T T P Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784 Score = 50.8 bits (120), Expect = 7e-06 Identities = 142/741 (19%), Positives = 232/741 (31%), Gaps = 86/741 (11%) Query: 290 KDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVT 349 +D +P MA + E+ V + V PT ++ +N PT T + VT Sbjct: 1853 EDQKPGGVIPMAFCLNYEI----NVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVT 1908 Query: 350 LLKE-TERASPIKMDLAPSKDMGP-PKENKKETERASPIKMD--LAPSKDMGPPKENKIV 405 T +P + + + P P +T +PI + P+ + Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968 Query: 406 PAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKA 465 P ++ ++T I++ V + T T P T +T Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP--- 2024 Query: 466 LPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPP 524 P Q P T I V P+ +P++ T VTP P Sbjct: 2025 -------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTP 2072 Query: 525 ETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKD--------- 575 T P +T P T+ P +T VTP Sbjct: 2073 -TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 2128 Query: 576 VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM-------ISPE-T 627 P + T TP P T I+ + + + PT ++P T Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188 Query: 628 VTGTGKKCSLPAEEDSVLEKL----GERKPCNSQPSELSSET-----SGIARPEEGRPVV 678 TGT + P + + G + P + + ++ T +G P Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248 Query: 679 SGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIG 734 + T TP + P + T T P T T T P T++ P PT Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2308 Query: 735 GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASA 794 P++ + + P P + P I + V P P P + Sbjct: 2309 TPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTT 2359 Query: 795 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAK 852 P + + +T T T T +T P + + + PT +T +T Sbjct: 2360 PITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416 Query: 853 SVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPF 903 P P + T+T+++ T T +GT P + + TP P+ P+TTP Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476 Query: 904 IDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKK 959 + P+ T TP + + T T+ P ++ +T I Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536 Query: 960 TEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2537 TQTPTTTPITTTTTVTPTPTP 2557 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2100 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2155 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2205 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2266 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2425 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2426 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTP 2626 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2169 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2224 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2274 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2335 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2444 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2494 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2495 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTP 2695 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2238 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2293 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2343 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2404 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2512 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2513 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2563 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2564 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTP 2764 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2307 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2362 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2412 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2473 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2582 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2632 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2633 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTP 2833 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2376 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2431 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2481 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2542 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2650 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2651 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2701 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2702 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTP 2902 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2445 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2500 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2550 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2611 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2719 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2720 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2770 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2771 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTP 2971 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2514 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2569 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2619 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2680 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2789 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2839 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2840 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTP 3040 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2583 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2638 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2688 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2749 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2857 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2858 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2908 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2909 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTP 3109 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2652 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2707 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2757 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2818 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2927 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2977 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 2978 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTP 3178 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2721 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2776 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2826 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2887 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2995 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 2996 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3046 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3047 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTP 3247 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2790 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2845 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2895 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 2956 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3064 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3065 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3115 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3116 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTP 3316 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2859 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2914 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2964 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3025 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3134 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3184 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3185 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTP 3385 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2928 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 2983 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3033 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3094 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3202 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3203 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3253 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3254 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTP 3454 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 2997 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3052 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3102 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3163 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3271 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3272 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3322 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3323 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTP 3523 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3066 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3121 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3171 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3232 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3340 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3341 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3391 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3392 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3448 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTP 3592 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3135 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3190 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3240 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3301 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3409 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3410 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3460 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3461 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTP 3661 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3204 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3259 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3309 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3370 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3478 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3479 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3529 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3530 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTP 3730 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3273 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3328 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3378 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3439 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3547 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3548 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3598 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3599 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTP 3799 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3342 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3397 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3447 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3508 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3667 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3668 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3724 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTP 3868 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3411 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3466 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3516 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3577 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3685 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3686 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3736 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3737 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3793 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3794 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTP 3937 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3480 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3535 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3585 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3645 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3646 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3805 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3806 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3862 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTP 4006 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3549 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3604 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3654 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3714 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3715 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3824 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3874 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3875 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3931 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 3992 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4051 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTP 4075 Score = 50.4 bits (119), Expect = 9e-06 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3618 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3673 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3723 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3784 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3833 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3892 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3893 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3943 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 3944 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4000 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 4001 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4060 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956 TP + P+ T TP + + T T+ P ++ +T I Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4120 Query: 957 EKKTEAAATTRKPESNAVTKTAGP 980 T+ TT + VT T P Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTP 4144 Score = 50.1 bits (118), Expect = 1e-05 Identities = 105/511 (20%), Positives = 160/511 (31%), Gaps = 70/511 (13%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3687 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3742 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3792 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3852 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3853 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3961 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3962 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 4012 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 4013 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4069 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS 928 TP + P+ T TP + + T T+ Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160 Score = 50.1 bits (118), Expect = 1e-05 Identities = 105/511 (20%), Positives = 160/511 (31%), Gaps = 70/511 (13%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3710 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3765 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3815 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3816 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3875 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 3876 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P P Sbjct: 3985 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 4035 Query: 792 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849 + P + + +T T T T +T P + + + PT +T + Sbjct: 4036 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4092 Query: 850 TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900 T P P + T+T+++ T T +GT P + + TP P+ P+T Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4152 Query: 901 TPFIDKKPTSAKPSST---TPRLSRLATNTS 928 TP + P+ T TP + + T T+ Sbjct: 4153 TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183 Score = 50.1 bits (118), Expect = 1e-05 Identities = 112/497 (22%), Positives = 161/497 (32%), Gaps = 71/497 (14%) Query: 451 TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509 T P T I T P P Q P T I V P+ +P+ Sbjct: 3871 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925 Query: 510 SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569 + T VTP P T P +T P T+ P +T Sbjct: 3926 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3976 Query: 570 VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 VTP P + T TP P T I+ + + + PT Sbjct: 3977 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4036 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675 +P T T T P G + P + + ++ T +G P Sbjct: 4037 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731 + T TP + P + T T P T T T P T++ P PT Sbjct: 4086 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4145 Query: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791 P++ + + P P + P I + V P P +P+ Sbjct: 4146 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP-----------TPTGT 4193 Query: 792 ASAPASRSGSKSTQTVAKTTTA--AAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM 849 + P + + ST +A+ TT+ +ST +SRS S+ L + T + T E M Sbjct: 4194 QTGPPTHT---STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE---M 4247 Query: 850 TAKSVPADLSRPKSTS----TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFID 905 T+ + P+ + P +TS S TTT P G A P PS TT Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA-PTPSTVQTTTTSA 4306 Query: 906 KKPTSAKPSSTTPRLSR 922 PT S TP + R Sbjct: 4307 WTPTPTPLS--TPSIIR 4321 Score = 30.8 bits (68), Expect = 7.8 Identities = 96/477 (20%), Positives = 149/477 (31%), Gaps = 80/477 (16%) Query: 268 TKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR-WPTET 326 T T ++PT +T + P+ + PT + V PT T Sbjct: 3999 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-----GTQTPTTTPITTTTTVTPTPTPT 4053 Query: 327 DVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPI 386 + + T T V P T +T +PI + P +T +PI Sbjct: 4054 GTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPT---PTPTGTQTPTTTPI 4109 Query: 387 KMD--LAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEV 444 + P+ + P ++ ++T I++ V + T Sbjct: 4110 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPT 4168 Query: 445 ALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIA----PAKDVAPSTVKEV 500 T P T +T P + P + P E+ P + P T + Sbjct: 4169 GTQTPTTTPITTTTTVTPTPT-PTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227 Query: 501 GLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAK 560 SPL+E+ L LPP +E+ T P AP Sbjct: 4228 S-----SPLTESTTLLST-----------------LPPAIEMTST---APPSTPTAPTTT 4262 Query: 561 DGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620 G TL+ PP S T + P +G + G S+APT Sbjct: 4263 SGGHTLS---------PPPSTTTSPP--------GTPTRGTT----------TGSSSAPT 4295 Query: 621 FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSG 680 T T P S++ G R +S + A EE V +G Sbjct: 4296 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEE---VYNG 4352 Query: 681 TGNDITTPPNKELPPSPEK-----KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTT 732 T D N L + E + P T P+K++ + +K P+S P +P P T Sbjct: 4353 TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK--PSSTPSKPTPGT 4407 >gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] Length = 984 Score = 75.9 bits (185), Expect = 2e-13 Identities = 110/460 (23%), Positives = 168/460 (36%), Gaps = 57/460 (12%) Query: 687 TPPNKELPPSPE------KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK- 739 +PP L PS KK + + P S A T+ S PK P+ GL++ Sbjct: 319 SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG 378 Query: 740 -PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 798 P L S + PP PS++P+ D K P A+ K + S P+ AP + Sbjct: 379 PPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQ 437 Query: 799 SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 858 S TQ + ++ AA AS+ P P P K + EG +TA + P+ Sbjct: 438 SFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSS 493 Query: 859 SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTT 917 S P +TST++ S P A V P+P+ PF + T A P++T Sbjct: 494 SLPTTTSTTAPTFQPVFSSMGPPASV--------PLPA-----PFFKQTTTPATAPTTTA 540 Query: 918 PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGG------GRAKVEKKTEAAATTRKP-- 969 P + LA+ TSA + + S ST++ G + V T A +P Sbjct: 541 PLFTGLASATSA--VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598 Query: 970 ------ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYS-HIQSKCGSKDNIKHVPGGGN 1022 + + T G I K PA S S H + + G G+ Sbjct: 599 FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGS 658 Query: 1023 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 1082 + S+ + + + + + F A++ + S PA Sbjct: 659 TLATSAPATSSQPTLTFSNTST------------PTFNIPFGSSAKSPLPSYPGANPQPA 706 Query: 1083 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 1122 GA + + G+ P P G +A A APT A Sbjct: 707 FGAAEGQPPGAAKPAL-APSFGSSFTFGNSAAPAAAPTPA 745 Score = 62.8 bits (151), Expect = 2e-09 Identities = 99/415 (23%), Positives = 145/415 (34%), Gaps = 50/415 (12%) Query: 601 ISEDSHLESLQDVGQSAAPTFMISPET--VTGTGKKCSLPAEEDSVLEKLGERKPCNSQP 658 I++ S +L ++ PT +++P T + + KK P E G P Sbjct: 303 ITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSP 362 Query: 659 SELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAK 718 + S + + G P + + + + PP L P P T+ T ++ Sbjct: 363 PKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETA 422 Query: 719 TQP--TSLPKQPAPTT---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKP 773 T+P TS P PAP G N P S P PA +SA P P P Sbjct: 423 TKPQATSAPS-PAPKQSFLFGTQNTSPSS----------PAAPAASSAPPMFKPIFTAPP 471 Query: 774 KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 833 K + P PS A+AP+S S +T T A T SS P +P Sbjct: 472 KSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQPVF------SSMGPPASVPLP 522 Query: 834 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSR 888 K PA TA S + + + +T S + PA G V S Sbjct: 523 APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582 Query: 889 VKATPMPSRPSTTPFIDKKPTSAKPSST-----------TPRLSRLATNTSAPDLKNVRS 937 V T + ++ PF+ P ++ S T P L T T+ + Sbjct: 583 VSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAV 642 Query: 938 KVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE---SNAVTKTAG-PIASAQKQP 988 ++ + G G T A AT+ +P SN T T P S+ K P Sbjct: 643 PTATSSSAADFSGFGSTLA---TSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP 694 Score = 48.9 bits (115), Expect = 3e-05 Identities = 128/601 (21%), Positives = 205/601 (34%), Gaps = 146/601 (24%) Query: 363 DLAPSKDMGPPKENKKETERASPIKMDLAPSKD------MGPPKENKIVPAKDLVLLSEI 416 D P K ++ + K+ L PS+ PP+ + A+DL L + Sbjct: 218 DTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKA 277 Query: 417 EVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVK 476 + N AL +++ A PP T T LP A +P Sbjct: 278 SLQWFNQ-------------ALEDKSDAASNSVTETPPITQPSFTF--TLPAAAPASP-- 320 Query: 477 DMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCL 536 P + +AP+ + ++K++ + P E+ A + PP+T +L Sbjct: 321 -----PTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL------ 369 Query: 537 PPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596 PP + L++ P L TL + PA + P ++T+A P Sbjct: 370 PP---LGLSQSGPPGLLPSPSFDSKPPTTLLGLI-PAPSMVPATDTKAPPT--------- 416 Query: 597 TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNS 656 E+ ++AP+ PA + S L G + S Sbjct: 417 --------LQAETATKPQATSAPS-----------------PAPKQSFL--FGTQNTSPS 449 Query: 657 QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE----LPPSPE-KKTKPLATTQPAK 711 P+ ++ ++ P +P+ T PP E PP P T P +++ P Sbjct: 450 SPAAPAASSA----PPMFKPI-------FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTT 498 Query: 712 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV 771 TST+ QP P AS +PA K+ + P+ Sbjct: 499 TSTTAPTFQPVFSSMGPP--------------ASVPLPAPFFKQTTTPATAPTTTAPLFT 544 Query: 772 KPKPIADAKAPEKRASPSKP-ASAPASRSG--SKSTQTVAKTTTAAAVAST----GPSSR 824 A AP ASPS AS PA G S S+ +V+ TT+ A AS G Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604 Query: 825 SPSTLLPKKPTAIKTEGKPAEVKKMT-------------------------------AKS 853 S ++ P + + GKP + T A S Sbjct: 605 SAASFTPAMGSIFQF-GKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATS 663 Query: 854 VPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913 PA S+P T +++ T + + A +PS A P P+ + + P +AKP Sbjct: 664 APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKP 720 Query: 914 S 914 + Sbjct: 721 A 721 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 74.3 bits (181), Expect = 6e-13 Identities = 78/327 (23%), Positives = 123/327 (37%), Gaps = 37/327 (11%) Query: 609 SLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETS-- 666 SL + +A+PT + TGT SL RKP + P+ + S TS Sbjct: 375 SLTGLSSTASPTGTPPRASPTGTPSTASLT------------RKPPRASPTGMLSRTSIT 422 Query: 667 ---GIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTS 723 A P P S TG TPP P + P T A + S + PT Sbjct: 423 KMDSTASPTRTPPRASPTG----TPPRAS-PTGTPSRASPTGTQSTASPTGSPSTASPTG 477 Query: 724 LPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783 P +PT G ++ ++ + A + PS S P + +P Sbjct: 478 SPSTASPT--GSPSRASLTRTPSRASLTKMESTASITRTPS-RASPTWTPSTASPTGSPS 534 Query: 784 KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPST-LLPKKPTAIKTEGK 842 + P+ A +R+ S+++ T + + S +R+PST LL + P + G Sbjct: 535 TALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGM 594 Query: 843 PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTP 902 P+ + P S + M T +++ T P A + +A+P + P +P Sbjct: 595 PSRT---------SPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASP 645 Query: 903 FIDKKPTSAKPSSTTPRLSRLATNTSA 929 P A P+ T PR S T + A Sbjct: 646 --TGTPPRASPTGTPPRASPTGTPSRA 670 Score = 67.8 bits (164), Expect = 6e-11 Identities = 126/586 (21%), Positives = 207/586 (35%), Gaps = 79/586 (13%) Query: 426 SSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE 485 S T S ++++ T AL T+P ++ T P A + A L T Sbjct: 129 SLTTTPSRASLSMTPSTAAAL----TMPSRASLTRT-----PPRASLTMTPSTASLTRTP 179 Query: 486 IAPAKDVAPSTVKEVGL--------LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLP 537 + PS G+ + + ++ T TPP + P Sbjct: 180 PRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGS------P 233 Query: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQT 597 P +++ ++T + G+L+ ++T ++ T + P + Sbjct: 234 PRASLSMMPSTALLIRTPPRASPTGMLS-RTSLTKMDSTASITRTPSRPSTASPTG-TPS 291 Query: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657 + +S SL + A+PT M+S ++T S+ R P + Sbjct: 292 RASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASIT---RTPSRAS 348 Query: 658 PSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKA 717 P+ S S P P S + +T + P + P T A + Sbjct: 349 PTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP 408 Query: 718 KTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIA 777 + PT + + + T + A+P + P AS P+ P P A Sbjct: 409 RASPTGMLSRTSITKMDST-------------ASPTRTPPRAS--PTGTP-------PRA 446 Query: 778 DAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAI 837 RASP+ S AS +GS ST + T + + + TG SR+ T P + + Sbjct: 447 SPTGTPSRASPTGTQST-ASPTGSPST--ASPTGSPSTASPTGSPSRASLTRTPSRASLT 503 Query: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVV--PSRVKATPMP 895 K E A + + +++ P P + S + T G+ A + PSR T P Sbjct: 504 KMEST-ASITRTPSRASPT--WTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTP 560 Query: 896 SRPS-TTP------------FIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGST 942 SR S TTP + + P SA P+ R S +SA + +K+ ST Sbjct: 561 SRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSA-----LLTKMDST 615 Query: 943 ENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQP 988 +I P RA + A+ T P + T T P AS P Sbjct: 616 ASITRTP--PRASPTETPPRASPTGTPPRASPTGTP-PRASPTGTP 658 Score = 62.8 bits (151), Expect = 2e-09 Identities = 88/353 (24%), Positives = 139/353 (39%), Gaps = 36/353 (10%) Query: 651 RKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQP 709 R P + + S S P + + +T TPP L +P T L T P Sbjct: 123 RSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPS--TASLTRTPP 180 Query: 710 AKTSTSK-AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPS 768 + T ++T PT +P + T + +L+ PP+ S + L Sbjct: 181 RASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASL-- 238 Query: 769 KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS-TGPSSRSPS 827 + P + P RASP+ S S + ST ++ +T + + AS TG SR+ Sbjct: 239 -SMMPSTALLIRTPP-RASPTGMLSR-TSLTKMDSTASITRTPSRPSTASPTGTPSRASL 295 Query: 828 TLLPKKPTAIKTEGKPAEVKKMTAKSVPAD-LSRPKSTSTSSMKKTTTLSGTAPAAGV-- 884 ++ P A + +M ++ P LSR TS + M T ++S T P A + Sbjct: 296 SMTPST----------ASLMRMLPRASPTGMLSR---TSLTKMDSTASISRTPPRASITR 342 Query: 885 VPSRVKATPMPSRPSTTPFIDK-KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943 PSR T PS S T + PT + +++ LS A+ T P + + ST Sbjct: 343 TPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPP-RASPTGTPSTA 401 Query: 944 NIKHQPGG-------GRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPA 989 ++ +P R + K A+ TR P + T T P AS P+ Sbjct: 402 SLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTP-PRASPTGTPS 453 Score = 53.9 bits (128), Expect = 9e-07 Identities = 87/380 (22%), Positives = 152/380 (40%), Gaps = 48/380 (12%) Query: 617 AAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPSELS-----SETSGIAR 670 A+PT S ++TGT + SL + L R P S S S + Sbjct: 11 ASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVS 70 Query: 671 PEEGRPVVSGTGNDITTPPN----KELPPSPEK-KTKPLATTQPAKTSTSKAKTQPTSLP 725 P + + +T P+ K +PP + +T P A+ + ST+ P+ Sbjct: 71 PSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLM-RRPSTASLTRSPSRAS 129 Query: 726 KQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783 P+ L+ P + A+ +P A+ + P AS + + + P A Sbjct: 130 LTTTPSR-ASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMP 188 Query: 784 KRASPS-KPASAPASRSGSKS--TQTVAK---TTTAAAVASTGPSSRSPSTLLPKKPTAI 837 R SP+ P++A ++ S + T+T+++ T T + TG R+ +++P I Sbjct: 189 SRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLI 248 Query: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897 +T + + ++ S+ K ST+S+ +T + TA G PSR + PS Sbjct: 249 RTPPRASPTGMLSRTSL------TKMDSTASITRTPSRPSTASPTG-TPSRASLSMTPST 301 Query: 898 PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVE 957 S + + +S T LSR + +K+ ST +I P RA + Sbjct: 302 ASLMRMLPR-------ASPTGMLSRTSL-----------TKMDSTASISRTP--PRASIT 341 Query: 958 KKTEAAATTRKPESNAVTKT 977 + A+ T KP + + T T Sbjct: 342 RTPSRASPTGKPSTASPTGT 361 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 70.5 bits (171), Expect = 9e-12 Identities = 84/308 (27%), Positives = 126/308 (40%), Gaps = 30/308 (9%) Query: 687 TPPNKELPPSPE------KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK- 739 +PP L PS KK + + P S A T+ S PK P+ GL++ Sbjct: 319 SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG 378 Query: 740 -PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 798 P L S + PP PS++P+ D K P A+ K + S P+ AP + Sbjct: 379 PPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQ 437 Query: 799 SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 858 S TQ + ++ AA AS+ P P K + EG +TA + P+ Sbjct: 438 SFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSS 493 Query: 859 SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTT 917 S P +TST++ S P A V P+P+ PF + T A P++T Sbjct: 494 SLPTTTSTTAPTFQPVFSSMGPPASV--------PLPA-----PFFKQTTTPATAPTTTA 540 Query: 918 PRLSRLATNTSAPDLKNVRSKVGSTENI-KHQPGGGRAKVEKKTEAAATTRKPESNAVTK 976 P + LA+ TSA + + S ST++ K G G V + + T+ ++ Sbjct: 541 PLFTGLASATSA--VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598 Query: 977 TAGPIASA 984 P ASA Sbjct: 599 FGAPQASA 606 Score = 60.5 bits (145), Expect = 9e-09 Identities = 98/414 (23%), Positives = 143/414 (34%), Gaps = 50/414 (12%) Query: 602 SEDSHLESLQDVGQSAAPTFMISPET--VTGTGKKCSLPAEEDSVLEKLGERKPCNSQPS 659 ++ S +L ++ PT +++P T + + KK P E G P Sbjct: 304 TQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPP 363 Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719 + S + + G P + + + + PP L P P T+ T ++ T Sbjct: 364 KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETAT 423 Query: 720 QP--TSLPKQPAPTT---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK 774 +P TS P PAP G N P S P PA +SA P P PK Sbjct: 424 KPQATSAPS-PAPKQSFLFGTQNTSPSS----------PAAPAASSASPMFKPIFTAPPK 472 Query: 775 PIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKP 834 + P PS A+AP+S S +T T A T SS P +P Sbjct: 473 SEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQPVF------SSMGPPASVPLPA 523 Query: 835 TAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSRV 889 K PA TA S + + + +T S + PA G V S V Sbjct: 524 PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV 583 Query: 890 KATPMPSRPSTTPFIDKKPTSAKPSST-----------TPRLSRLATNTSAPDLKNVRSK 938 T + ++ PF+ P ++ S T P L T T+ Sbjct: 584 STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVP 643 Query: 939 VGSTENIKHQPGGGRAKVEKKTEAAATTRKPE---SNAVTKTAG-PIASAQKQP 988 ++ + G G T A AT+ +P SN T T P S+ K P Sbjct: 644 TATSSSAADFSGFGSTLA---TSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP 694 Score = 56.2 bits (134), Expect = 2e-07 Identities = 150/682 (21%), Positives = 229/682 (33%), Gaps = 145/682 (21%) Query: 363 DLAPSKDMGPPKENKKETERASPIKMDLAPSKD------MGPPKENKIVPAKDLVLLSEI 416 D P K ++ + K+ L PS+ PP+ + A+DL L + Sbjct: 218 DTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKA 277 Query: 417 EVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVK 476 + N AL +++ A PP T T LP A +P Sbjct: 278 SLQWFNQ-------------ALEDKSDAASNSVTETPPTTQPSFTF--TLPAAATASP-- 320 Query: 477 DMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCL 536 P + +AP+ + ++K++ + P E+ A + PP+T +L Sbjct: 321 -----PTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL------ 369 Query: 537 PPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596 PP + L++ P L TL + PA + P ++T+A P Sbjct: 370 PP---LGLSQSGPPGLLPSPSFDSKPPTTLLGLI-PAPSMVPATDTKAPPT--------- 416 Query: 597 TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNS 656 E+ ++AP+ PA + S L G + N+ Sbjct: 417 --------LQAETATKPQATSAPS-----------------PAPKQSFL--FGTQ---NT 446 Query: 657 QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE----LPPSPE-KKTKPLATTQPAK 711 PS ++ + A P +P+ T PP E PP P T P +++ P Sbjct: 447 SPSSPAAPAASSASPMF-KPI-------FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTT 498 Query: 712 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV 771 TST+ QP P AS +PA K+ + P+ Sbjct: 499 TSTTAPTFQPVFSSMGPP--------------ASVPLPAPFFKQTTTPATAPTTTAPLFT 544 Query: 772 KPKPIADAKAPEKRASPSKP-ASAPASRSG--SKSTQTVAKTTTAAAVAST----GPSSR 824 A AP ASPS AS PA G S S+ +V+ TT+ A AS G Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604 Query: 825 SPSTLLPK--------KPTAIKT--------EGKPAEVKKMT--------------AKSV 854 S ++ P KP A+ T + P V T A S Sbjct: 605 SAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSA 664 Query: 855 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 914 PA S+P T +++ T + + A +PS A P P+ + + P +AKP+ Sbjct: 665 PATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKPA 721 Query: 915 STTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAV 974 T S SA IK P ++ T AT A Sbjct: 722 LTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQ-PTFGGATHSAFGLKAT 780 Query: 975 TKTAGPIASAQKQPAGKVQIVS 996 G AS+Q G + S Sbjct: 781 ASAFGAPASSQPAFGGSTAVFS 802 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 70.1 bits (170), Expect = 1e-11 Identities = 119/546 (21%), Positives = 188/546 (34%), Gaps = 76/546 (13%) Query: 483 ETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGK--DVTPPPETEVVLIKNVCLPPEM 540 ET++ V P+ VK + SP + A GK DVTP +K LPP Sbjct: 209 ETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ-------VKGGALPPAK 261 Query: 541 -------------EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP- 586 E + +E++ PA A + +L + PAK P T A P Sbjct: 262 RAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPG 321 Query: 587 ------------VPIKDMEIAQTQKGISEDSHLES-----------LQDVGQSAAPTFMI 623 P +D E + + SE+ + VG ++AP Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381 Query: 624 SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 + + PA + K E +S+ S+ E A+P P V Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441 Query: 684 DITTPPNKELPPSPEKKTKPLAT-TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 P K P+P +KT P A Q K + S + A + KP+ Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802 + + PA+ + + P K P A E+ + S S+ +S Sbjct: 502 KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD---- 557 Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862 + TA A A +S +L KPT+ +G P +K +V +P Sbjct: 558 -----GEVPTAVAPA----QEKSLGNILQAKPTSSPAKGPP---QKAGPVAVQVKAEKPM 605 Query: 863 STSTSSMKKTTTL-SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921 S SS + + + S APAA + +A P P T K T+A + +++ Sbjct: 606 DNSESSEESSDSADSEEAPAA---MTAAQAKPALKIPQTKACPKKTNTTA-----SAKVA 657 Query: 922 RLATNTSAP-DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980 + T AP S GS+ + GG + E + + + + E + T G Sbjct: 658 PVRVGTQAPRKAGTATSPAGSSPAV---AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 714 Query: 981 IASAQK 986 S K Sbjct: 715 AKSVGK 720 Score = 57.8 bits (138), Expect = 6e-08 Identities = 175/850 (20%), Positives = 301/850 (35%), Gaps = 131/850 (15%) Query: 157 SATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAE-PPQP 215 S++ DTS + + D ++ + P + SV SP ++ +P V + PQ Sbjct: 198 SSSEDTSSSSDETD-VEGKPSVKPAQV----KASSVSTKESPARKAAPAPGKVGDVTPQV 252 Query: 216 TAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALA 275 L AK + EE ++ G ++ + AP+ A + L + A A Sbjct: 253 KGGALPPAKRAKKPEEESESSEE-----GSESEEEAPAGTRSQVKASEKILQVRAASAPA 307 Query: 276 KDMES-------PTKLDVTLAKDMQPSMESDM------ALVKDMELPTEKEVALVKDVRW 322 K P K ++ E D + + E P K + K Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK 367 Query: 323 PTETDVSSA-------KNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKE 375 ++ +SA K + PA + E S + + S++ P + Sbjct: 368 TSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQA 427 Query: 376 NKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVA-QANDIISSTEISSAE 434 K + +A ++ AP+K+ P K ++++V Q D SS+E S ++ Sbjct: 428 --KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485 Query: 435 KVALSSETEVA---LARDMTLPPETNV---ILTKDKALPLEAEVAPVKDMAQLPE----- 483 + AL++ L + + P + + L K +V P AQ+ + Sbjct: 486 REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545 Query: 484 ----TEIAPAKD------VAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK- 532 E + + D VAP+ K +G + P S PP + V ++ Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG------PPQKAGPVAVQV 599 Query: 533 NVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDM 592 P + + E A EAP A A PA +P +T+A P K Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT-----AAQAKPALKIP---QTKACP---KKT 648 Query: 593 EIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERK 652 + K ++ + G + +P SP GT + PAE+ S Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGS-SPAVAGGTQR----PAEDSS--------- 694 Query: 653 PCNSQPSELSSETSGIA-RPEEGRPVVSGTGNDITTPPNKE-----LPPSPEKKTKPLAT 706 +S+ S+ E +G+A + + V G + P K P KT P T Sbjct: 695 --SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752 Query: 707 TQPAKTSTSKAKTQPTSLPKQPA--PTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 764 A+ ++ S ++ A P + KK + A+ AP + +++ Sbjct: 753 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA---- 808 Query: 765 ILPSKDVKPKPIADAKAPEKRASPSK-PASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 823 P K V A ++P K P + P ++ G S +V K AA A TGP Sbjct: 809 --PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE 866 Query: 824 RSPS------------TLLPKKPTA----IKTEGKPA-EVKKMTAKSVPADLSRPKSTST 866 S S TL KP+ I+ PA E + A P + P + Sbjct: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 926 Query: 867 SSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST--------TP 918 + + S + + G P+ V + + P F+D + A P++T TP Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI--FVDPNRSPAGPAATPAQAQAASTP 984 Query: 919 RLSRLATNTS 928 R +R + +T+ Sbjct: 985 RKARASESTA 994 Score = 51.2 bits (121), Expect = 6e-06 Identities = 87/404 (21%), Positives = 136/404 (33%), Gaps = 27/404 (6%) Query: 617 AAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-SGIARPEEGR 675 A P + +V G S+ + + EK G K NS P + +T + + + R Sbjct: 101 ATPRLASTNSSVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPR 158 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG 735 + N +E P A +P S +A + T + G Sbjct: 159 KSAEPSANTTLVSETEEEGSVPAFG----AAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214 Query: 736 LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 795 K + A + K A P+ DV P+ A P KRA + S Sbjct: 215 --KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE- 271 Query: 796 ASRSGSKSTQTVAKTTTAAAVASTG----PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851 +S GS+S + T + AS ++ +P+ P K GK V T Sbjct: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 331 Query: 852 KSVPADLSRPKSTSTSSMKKTTTLSGT---APAAGVVPSRVKATPMPSRPSTTPFIDKKP 908 P + S S +S ++ T + A A+G S+V A P++ S K Sbjct: 332 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT-SQVGAASAPAKESPR----KGA 386 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRK 968 A P T P +++ D S+ S E+ + +AK K Sbjct: 387 APAPPGKTGPAVAKAQAGKREED-----SQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441 Query: 969 PESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKD 1012 P + K A P + PA V K+ S S+ D Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485 Score = 40.8 bits (94), Expect = 0.007 Identities = 159/813 (19%), Positives = 278/813 (34%), Gaps = 106/813 (13%) Query: 190 WSVEALNSPHSESFVS----PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGL 245 W ++ +S S S P AVA P Q ++ L + + + PP +A + + + Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVA-PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599 Query: 246 K----------TTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPS 295 K + + + S ++E A A A K + + + P K + T + + P Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659 Query: 296 MESDMALVK--DMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA----PAKDVT 349 A K P A+ + P E SS ++ +T +A AK V Sbjct: 660 RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG 719 Query: 350 LLKETERAS-PIKMDLAP-SKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPA 407 + + AS P+K L + + P K T+ + + D S++ +E PA Sbjct: 720 KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA 779 Query: 408 KDLVLLSEIEV----AQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN-----V 458 + + + + A A + IS+ KV ++ + PP N V Sbjct: 780 QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839 Query: 459 ILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMAL-- 516 + ++P + AQ E + + + + +E L + P +T Sbjct: 840 LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899 Query: 517 ----------GKDVTPPPETEVVLI---KNVCLPPEMEVALTEDQVPALKTEAPLAKDGV 563 G TPP +T K E + ++ + PA T A + K + Sbjct: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959 Query: 564 LTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMI 623 + + N +PA ++ +A P K T + S +S E + Q P Sbjct: 960 IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019 Query: 624 SPETV------------------------TGTGKKCSLPAEE-DSVLEKLGERKPCNS-- 656 + T+ GKK PA + DS + L P ++ Sbjct: 1020 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV 1079 Query: 657 --------QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ 708 + +L PE + + + + E P K L Sbjct: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE-GPQGAKSAHTLVGPT 1138 Query: 709 PAKTSTSKAKTQPTSLPKQ---PAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSI 765 P++T T +T S P+ + + G ++ A+ A PK + S S Sbjct: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV-SST 1197 Query: 766 LPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA--VASTGPSS 823 L +KD P +AK P++ A P + + + Q K A AST Sbjct: 1198 LAAKD-DPDGKQEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQ 1255 Query: 824 RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKK-----TTTLSGT 878 + + L +P + A V K+ + + + + T+ S +K LSG Sbjct: 1256 SNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGD 1315 Query: 879 APAAGVVPSRVK----------ATPMPSRPSTT 901 PAA S+ K A+ P + STT Sbjct: 1316 QPAARTPRSKKKKKLGAGEGGEASVSPEKTSTT 1348 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 70.1 bits (170), Expect = 1e-11 Identities = 119/546 (21%), Positives = 188/546 (34%), Gaps = 76/546 (13%) Query: 483 ETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGK--DVTPPPETEVVLIKNVCLPPEM 540 ET++ V P+ VK + SP + A GK DVTP +K LPP Sbjct: 209 ETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ-------VKGGALPPAK 261 Query: 541 -------------EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP- 586 E + +E++ PA A + +L + PAK P T A P Sbjct: 262 RAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPG 321 Query: 587 ------------VPIKDMEIAQTQKGISEDSHLES-----------LQDVGQSAAPTFMI 623 P +D E + + SE+ + VG ++AP Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381 Query: 624 SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 + + PA + K E +S+ S+ E A+P P V Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441 Query: 684 DITTPPNKELPPSPEKKTKPLAT-TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742 P K P+P +KT P A Q K + S + A + KP+ Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501 Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802 + + PA+ + + P K P A E+ + S S+ +S Sbjct: 502 KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD---- 557 Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862 + TA A A +S +L KPT+ +G P +K +V +P Sbjct: 558 -----GEVPTAVAPA----QEKSLGNILQAKPTSSPAKGPP---QKAGPVAVQVKAEKPM 605 Query: 863 STSTSSMKKTTTL-SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921 S SS + + + S APAA + +A P P T K T+A + +++ Sbjct: 606 DNSESSEESSDSADSEEAPAA---MTAAQAKPALKIPQTKACPKKTNTTA-----SAKVA 657 Query: 922 RLATNTSAP-DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980 + T AP S GS+ + GG + E + + + + E + T G Sbjct: 658 PVRVGTQAPRKAGTATSPAGSSPAV---AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 714 Query: 981 IASAQK 986 S K Sbjct: 715 AKSVGK 720 Score = 56.6 bits (135), Expect = 1e-07 Identities = 186/948 (19%), Positives = 324/948 (34%), Gaps = 121/948 (12%) Query: 190 WSVEALNSPHSESFVS----PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGL 245 W ++ +S S S P AVA P Q ++ L + + + PP +A + + + Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVA-PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599 Query: 246 K----------TTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPS 295 K + + + S ++E A A A K + + + P K + T + + P Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659 Query: 296 MESDMALVK--DMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA----PAKDVT 349 A K P A+ + P E SS ++ +T +A AK V Sbjct: 660 RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG 719 Query: 350 LLKETERAS-PIKMDLAP-SKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPA 407 + + AS P+K L + + P K T+ + + D S++ +E PA Sbjct: 720 KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA 779 Query: 408 KDLVLLSEIEV----AQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN-----V 458 + + + + A A + IS+ KV ++ + PP N V Sbjct: 780 QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839 Query: 459 ILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMAL-- 516 + ++P + AQ E + + + + +E L + P +T Sbjct: 840 LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899 Query: 517 ----------GKDVTPPPETEVVLI---KNVCLPPEMEVALTEDQVPALKTEAPLAKDGV 563 G TPP +T K E + ++ + PA T A + K + Sbjct: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959 Query: 564 LTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMI 623 + + N +PA ++ +A P K T + S +S E + Q P Sbjct: 960 IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019 Query: 624 SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683 + T +P + K +S+ S S+ + +EG N Sbjct: 1020 NVVT---------MPTAHPRIAPKASMAGASSSKESSRISD----GKKQEGPATQVSKKN 1066 Query: 684 DITTPPN----KELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK 739 + P K L + P+A TQP+ S T P + P Q G NK Sbjct: 1067 PASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSP-QSTSVQAKGTNK- 1124 Query: 740 PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 799 PK P V A + S D + + + + E P SA Sbjct: 1125 ----------LRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174 Query: 800 GSKSTQTVAKTTTAAAVAS--TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 857 T+T+ + T A + PS S + T ++ A K ++ SV + Sbjct: 1175 TPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSST 1234 Query: 858 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 917 L+ K AAG++ + S TTP +KP K + Sbjct: 1235 LAAKDDPDGKQEAK------PQQAAGMLSPKTGGKEAAS--GTTPQKSRKP---KKGAGN 1283 Query: 918 PRLSRLATNTSAPD--------LKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKP 969 P+ S LA ++ L + + + + R KV T+ ++RK Sbjct: 1284 PQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK--ESSRKG 1341 Query: 970 ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKK 1029 + K +G QPA + KK K G+ + GG + +K Sbjct: 1342 WESRKRKLSG------DQPAARTPRSKKK-------KKLGAGE-------GGEASVSPEK 1381 Query: 1030 VDISKVSSKCGSKA--NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLD 1075 + KA ++K K G G + + K +E+ Q +G+++ Sbjct: 1382 TSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE 1429 Score = 51.2 bits (121), Expect = 6e-06 Identities = 87/404 (21%), Positives = 136/404 (33%), Gaps = 27/404 (6%) Query: 617 AAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-SGIARPEEGR 675 A P + +V G S+ + + EK G K NS P + +T + + + R Sbjct: 101 ATPRLASTNSSVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPR 158 Query: 676 PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG 735 + N +E P A +P S +A + T + G Sbjct: 159 KSAEPSANTTLVSETEEEGSVPAFG----AAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214 Query: 736 LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 795 K + A + K A P+ DV P+ A P KRA + S Sbjct: 215 --KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE- 271 Query: 796 ASRSGSKSTQTVAKTTTAAAVASTG----PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851 +S GS+S + T + AS ++ +P+ P K GK V T Sbjct: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 331 Query: 852 KSVPADLSRPKSTSTSSMKKTTTLSGT---APAAGVVPSRVKATPMPSRPSTTPFIDKKP 908 P + S S +S ++ T + A A+G S+V A P++ S K Sbjct: 332 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT-SQVGAASAPAKESPR----KGA 386 Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRK 968 A P T P +++ D S+ S E+ + +AK K Sbjct: 387 APAPPGKTGPAVAKAQAGKREED-----SQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441 Query: 969 PESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKD 1012 P + K A P + PA V K+ S S+ D Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.304 0.123 0.336 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,761,688 Number of Sequences: 37866 Number of extensions: 2769982 Number of successful extensions: 19907 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 168 Number of HSP's successfully gapped in prelim test: 1329 Number of HSP's that attempted gapping in prelim test: 10404 Number of HSP's gapped (non-prelim): 5459 length of query: 1152 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1039 effective length of database: 13,968,660 effective search space: 14513437740 effective search space used: 14513437740 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.