Guide to the Human Genome
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Search of human proteins with 47519639

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
sapiens]
         (1152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...  2253   0.0  
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...  2124   0.0  
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...   956   0.0  
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...   723   0.0  
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...   213   8e-55
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s...   207   5e-53
gi|47519699 microtubule-associated protein 4 isoform 3 [Homo sap...   195   2e-49
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap...   193   7e-49
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap...   190   8e-48
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa...   189   2e-47
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ...   185   2e-46
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa...   184   3e-46
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap...   147   6e-35
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap...   140   7e-33
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa...   128   4e-29
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  115   2e-25
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  115   2e-25
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  115   2e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   115   2e-25
gi|110349719 titin isoform N2-A [Homo sapiens]                         96   2e-19
gi|91982772 mucin 17 [Homo sapiens]                                    88   5e-17
gi|38261962 activating transcription factor 7 interacting protei...    87   1e-16
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     83   2e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni...    80   9e-15
gi|116284392 mucin 2 precursor [Homo sapiens]                          77   9e-14
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           76   2e-13
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    74   6e-13
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    70   9e-12
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    70   1e-11
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    70   1e-11

>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
          Length = 1152

 Score = 2253 bits (5839), Expect = 0.0
 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%)

Query: 1    MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60
            MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
Sbjct: 1    MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60

Query: 61   ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120
            ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
Sbjct: 61   ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120

Query: 121  EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180
            EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
Sbjct: 121  EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180

Query: 181  CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240
            CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
Sbjct: 181  CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240

Query: 241  IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300
            IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
Sbjct: 241  IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300

Query: 301  ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360
            ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
Sbjct: 301  ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360

Query: 361  KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420
            KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
Sbjct: 361  KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420

Query: 421  ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480
            ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
Sbjct: 421  ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480

Query: 481  LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540
            LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
Sbjct: 481  LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540

Query: 541  EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600
            EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG
Sbjct: 541  EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600

Query: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660
            ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE
Sbjct: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660

Query: 661  LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720
            LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ
Sbjct: 661  LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720

Query: 721  PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780
            PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
Sbjct: 721  PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780

Query: 781  APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840
            APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
Sbjct: 781  APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840

Query: 841  GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900
            GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
Sbjct: 841  GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900

Query: 901  TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960
            TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
Sbjct: 901  TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960

Query: 961  EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020
            EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
Sbjct: 961  EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020

Query: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080
            GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
Sbjct: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080

Query: 1081 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1140
            PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA
Sbjct: 1081 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1140

Query: 1141 QTLDSQIQETSI 1152
            QTLDSQIQETSI
Sbjct: 1141 QTLDSQIQETSI 1152


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
            sapiens]
          Length = 1135

 Score = 2124 bits (5504), Expect = 0.0
 Identities = 1088/1089 (99%), Positives = 1088/1089 (99%)

Query: 1    MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60
            MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
Sbjct: 1    MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60

Query: 61   ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120
            ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
Sbjct: 61   ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 120

Query: 121  EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180
            EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
Sbjct: 121  EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 180

Query: 181  CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240
            CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
Sbjct: 181  CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 240

Query: 241  IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300
            IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
Sbjct: 241  IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 300

Query: 301  ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360
            ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
Sbjct: 301  ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 360

Query: 361  KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420
            KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
Sbjct: 361  KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 420

Query: 421  ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480
            ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
Sbjct: 421  ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480

Query: 481  LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540
            LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
Sbjct: 481  LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540

Query: 541  EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600
            EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG
Sbjct: 541  EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 600

Query: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660
            ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE
Sbjct: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 660

Query: 661  LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720
            LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ
Sbjct: 661  LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 720

Query: 721  PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780
            PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
Sbjct: 721  PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 780

Query: 781  APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840
            APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
Sbjct: 781  APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840

Query: 841  GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900
            GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
Sbjct: 841  GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 900

Query: 901  TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960
            TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
Sbjct: 901  TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 960

Query: 961  EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020
            EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
Sbjct: 961  EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 1020

Query: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080
            GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
Sbjct: 1021 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1080

Query: 1081 PAGGAVKTE 1089
            PAGGAVK E
Sbjct: 1081 PAGGAVKIE 1089


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sapiens]
          Length = 887

 Score =  956 bits (2471), Expect = 0.0
 Identities = 509/589 (86%), Positives = 522/589 (88%), Gaps = 23/589 (3%)

Query: 580  SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
            S+ EA P  + D  +  T  KG+     +D  LE+ Q + +        S     G GKK
Sbjct: 306  SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358

Query: 635  --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
               S  AE         +   L  L  +     Q      +++GIARPEEGRPVVSGTGN
Sbjct: 359  EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418

Query: 684  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743
            DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL
Sbjct: 419  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478

Query: 744  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803
            ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS
Sbjct: 479  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538

Query: 804  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
            TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS
Sbjct: 539  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598

Query: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
            TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL
Sbjct: 599  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658

Query: 924  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983
            ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS
Sbjct: 659  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 718

Query: 984  AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043
            AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA
Sbjct: 719  AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 778

Query: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 1103
            NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA
Sbjct: 779  NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 838

Query: 1104 GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 1152
            GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI
Sbjct: 839  GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 887


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
            sapiens]
          Length = 817

 Score =  723 bits (1866), Expect = 0.0
 Identities = 406/589 (68%), Positives = 434/589 (73%), Gaps = 94/589 (15%)

Query: 580  SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
            S+ EA P  + D  +  T  KG+     +D  LE+ Q + +        S     G GKK
Sbjct: 306  SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358

Query: 635  --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
               S  AE         +   L  L  +     Q      +++GIARPEEGRPVVSGTGN
Sbjct: 359  EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418

Query: 684  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743
            DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL
Sbjct: 419  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478

Query: 744  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803
            ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS
Sbjct: 479  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538

Query: 804  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
            TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS
Sbjct: 539  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598

Query: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
            TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL
Sbjct: 599  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658

Query: 924  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983
            ATNTSAPDLKNVRSKVGSTENIKHQPGGGR +++                          
Sbjct: 659  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQ-------------------------- 692

Query: 984  AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDI-SKVSSKCGSK 1042
                        +KKV  S + SKCGSK NIKH PGGG+V+I+++K++   K  +K GS 
Sbjct: 693  ------------NKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSL 740

Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPP 1102
             N+ H P G                                GAVKTEGGGSEAPLCPGPP
Sbjct: 741  DNVGHLPAG--------------------------------GAVKTEGGGSEAPLCPGPP 768

Query: 1103 AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETS 1151
            AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQET+
Sbjct: 769  AGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
            sapiens]
          Length = 776

 Score =  213 bits (542), Expect = 8e-55
 Identities = 170/529 (32%), Positives = 238/529 (44%), Gaps = 86/529 (16%)

Query: 573  AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
            A  +P      A P+P+  +    T+   SE       +  GQ A   F    E      
Sbjct: 253  ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312

Query: 633  KKCSLPAEEDSVLEKL------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT 686
            K+    A  +  L +       GE            ++ + +  P E +P  +  G  ++
Sbjct: 313  KE---QAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVS 369

Query: 687  TPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT---QPTSLPKQPAPTTIGGLNKKPMS 742
              P  +     + K    +  + AKTST S AKT   +P   PK P P    G +   + 
Sbjct: 370  RVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----GSSDPLIQ 425

Query: 743  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
             +S  V   PP  P   S+  S   S   K   +  A    K A+P + A+ P  +  + 
Sbjct: 426  PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP-RGAAPPGQKGQAN 484

Query: 803  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRP 861
            +T+  AKT  A     T PSS +        P   ++E G+P +    +  S P     P
Sbjct: 485  ATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTP 541

Query: 862  KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921
             S S +            P+    P+R      P + +      K P+SAK        S
Sbjct: 542  GSRSRT------------PSLPTPPTRE-----PKKVAVVRTPPKSPSSAK--------S 576

Query: 922  RLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
            RL T     PDLKNV+SK+GSTEN+KHQPGGG                            
Sbjct: 577  RLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG---------------------------- 608

Query: 981  IASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCG 1040
                      KVQI++KK+  S++QSKCGSKDNIKHVPGGG+VQI  K VD+SKV+SKCG
Sbjct: 609  ----------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCG 658

Query: 1041 SKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
            S  NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 659  SLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 707


>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
            sapiens]
          Length = 758

 Score =  207 bits (527), Expect = 5e-53
 Identities = 172/527 (32%), Positives = 224/527 (42%), Gaps = 100/527 (18%)

Query: 573  AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
            A  +P      A P+P+  +    T+   SE       +  GQ A   F    E      
Sbjct: 253  ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312

Query: 633  KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692
            K      E+    E LG R      P E          PE   P +     +   P   E
Sbjct: 313  K------EQAHSEEHLG-RAAFPGAPGE---------GPEARGPSLGEDTKEADLPEPSE 356

Query: 693  LPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP 752
              P+   + KP++     K          T    + A T+     K   +      P   
Sbjct: 357  KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR-----PCLS 411

Query: 753  PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV----- 807
            PK P   S+ P I PS        + A  PE  +SP K  S+  SR+GS   + +     
Sbjct: 412  PKHPTPGSSDPLIQPS--------SPAVCPEPPSSP-KHVSSVTSRTGSSGAKEMKLKGA 462

Query: 808  ---AKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
                K  T    A  G   ++ +T +P K P A KT     E  K   +S     S P S
Sbjct: 463  DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 519

Query: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
              T   +  T    T P        V  TP            K P+SAK        SRL
Sbjct: 520  PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 560

Query: 924  ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
             T     PDLKNV+SK+GSTEN+KHQPGGG                              
Sbjct: 561  QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 590

Query: 983  SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
                    KVQI++KK+  S++QSKCGSKDNIKHVPGGG+VQI  K VD+SKV+SKCGS 
Sbjct: 591  --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642

Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
             NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 643  GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 689


>gi|47519699 microtubule-associated protein 4 isoform 3 [Homo
          sapiens]
          Length = 99

 Score =  195 bits (495), Expect = 2e-49
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60
          MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
Sbjct: 1  MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 60

Query: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT 97
          ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT
Sbjct: 61 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTT 97


>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sapiens]
          Length = 502

 Score =  193 bits (491), Expect = 7e-49
 Identities = 132/356 (37%), Positives = 182/356 (51%), Gaps = 69/356 (19%)

Query: 748  VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 794
            +P +PP  PA          A    ++ PS  K  K K ++D   K+PEKR+S  +P+S 
Sbjct: 133  LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191

Query: 795  PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 854
               R G    +     +  ++++S+   +     +     +   T   P     +T  + 
Sbjct: 192  LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-ITPGTP 250

Query: 855  PADLSR-PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913
            P+  SR P +  T S  +T    GT  +A +VPS  K   + + P               
Sbjct: 251  PSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK-------------- 296

Query: 914  SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973
            S  TP+  RL  N   PDLKNV+SK+GST+NIK+QP GG+                    
Sbjct: 297  SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNIKYQPKGGQ-------------------- 335

Query: 974  VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033
                              V+I++KK+ +S +QS+CGSKDNIKH  GGGNVQI  KK+D+S
Sbjct: 336  ------------------VRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLS 377

Query: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
             V+SKCGS  NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN  H+P GG VK +
Sbjct: 378  HVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 433


>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sapiens]
          Length = 559

 Score =  190 bits (482), Expect = 8e-48
 Identities = 143/420 (34%), Positives = 201/420 (47%), Gaps = 81/420 (19%)

Query: 688  PPNKELPPSP--------EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK 739
            PP+   PPSP        E+     +   P+    +K K   ++L K PA   + G  K 
Sbjct: 134  PPSP--PPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSNSTLSKIPA---LQGSTKS 188

Query: 740  PMSLASGLVPAAPPK---------RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK 790
            P    S   P+   +         +P  A +   +  SK      +   K+PEKR+S  +
Sbjct: 189  PRY--SSACPSTTKRATFSDSLLIQPTSAGSTDRLPYSKSGNKDGVT--KSPEKRSSLPR 244

Query: 791  PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMT 850
            P+S    R G    +     +  ++++S+   +     +     +   T   P     +T
Sbjct: 245  PSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-IT 303

Query: 851  AKSVPADLSR-PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPT 909
              + P+  SR P +  T S  +T    GT  +A +VPS  K   + + P           
Sbjct: 304  PGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK---------- 353

Query: 910  SAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKP 969
                S  TP+  RL  N   PDLKNV+SK+GST+NIK+QP GG+                
Sbjct: 354  ----SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNIKYQPKGGQ---------------- 392

Query: 970  ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKK 1029
                                  V+I++KK+ +S +QS+CGSKDNIKH  GGGNVQI  KK
Sbjct: 393  ----------------------VRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKK 430

Query: 1030 VDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
            +D+S V+SKCGS  NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN  H+P GG VK +
Sbjct: 431  IDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 490


>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
            sapiens]
          Length = 441

 Score =  189 bits (479), Expect = 2e-47
 Identities = 131/380 (34%), Positives = 180/380 (47%), Gaps = 68/380 (17%)

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 790
            T  GL + P+   +      P    + A + P+   ++DV   P+ D  AP K+A+    
Sbjct: 39   TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94

Query: 791  ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847
               P    A  +G   T ++          +   S     T    K    K +G   + K
Sbjct: 95   TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150

Query: 848  KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 899
              T +       + ++ +T    KT     T P++G  P        S   +   P   S
Sbjct: 151  IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210

Query: 900  TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 949
             TP +   PT            P S +   SRL T     PDLKNV+SK+GSTEN+KHQP
Sbjct: 211  RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270

Query: 950  GGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCG 1009
            GGG                                      KVQI++KK+  S++QSKCG
Sbjct: 271  GGG--------------------------------------KVQIINKKLDLSNVQSKCG 292

Query: 1010 SKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQA 1069
            SKDNIKHVPGGG+VQI  K VD+SKV+SKCGS  NI HKPGGG V+++S+KL+FK++ Q+
Sbjct: 293  SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS 352

Query: 1070 KVGSLDNVGHLPAGGAVKTE 1089
            K+GSLDN+ H+P GG  K E
Sbjct: 353  KIGSLDNITHVPGGGNKKIE 372



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 42/201 (20%), Positives = 69/201 (34%), Gaps = 23/201 (11%)

Query: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVP-------------PLSETEA 584
           P  E +  +    A    APL  +G         P  ++P             P  E EA
Sbjct: 59  PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118

Query: 585 TPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644
                +   +++++ G   D       D     A     +P    G      +PA+    
Sbjct: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178

Query: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPL 704
                 + P +S     S + SG + P  G P   GT    +  P+   PP+ E K   +
Sbjct: 179 -----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAV 228

Query: 705 ATTQPAKTSTSKAKTQPTSLP 725
             T P   S++K++ Q   +P
Sbjct: 229 VRTPPKSPSSAKSRLQTAPVP 249


>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
            sapiens]
          Length = 412

 Score =  185 bits (470), Expect = 2e-46
 Identities = 127/347 (36%), Positives = 167/347 (48%), Gaps = 71/347 (20%)

Query: 754  KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 804
            + P   ++     P+ + +   I D  + E  A+     +   S+S          +K  
Sbjct: 57   EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116

Query: 805  QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
                K  T    A  G   ++ +T +P K P A KT     E  K   +S     S P S
Sbjct: 117  DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173

Query: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
              T   +  T    T P        V  TP            K P+SAK        SRL
Sbjct: 174  PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214

Query: 924  ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
             T     PDLKNV+SK+GSTEN+KHQPGGG                              
Sbjct: 215  QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 244

Query: 983  SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
                    KVQI++KK+  S++QSKCGSKDNIKHVPGGG+VQI  K VD+SKV+SKCGS 
Sbjct: 245  --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 296

Query: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
             NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 297  GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 343



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 94/400 (23%), Positives = 141/400 (35%), Gaps = 58/400 (14%)

Query: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657
           Q G +     E   D G   +P   +   T  G+ +  S  ++  S      E       
Sbjct: 26  QGGYTMHQDQEGDTDAGLKESP---LQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDT 82

Query: 658 PSELSSETSG-IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 716
           PS L  E +G + +         GTG+D       +     + KTK +AT + A     K
Sbjct: 83  PS-LEDEAAGHVTQARMVSKSKDGTGSD------DKKAKGADGKTK-IATPRGAAPPGQK 134

Query: 717 AKTQPTSLPKQ--PAPTTIGGLNKKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKP 773
            +   T +P +  PAP T     + P S   SG      P  P   S  PS+      +P
Sbjct: 135 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194

Query: 774 KPIADAKAPEKRASPSKP--ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLP 831
           K +A  + P K  S +K    +AP      K+ +        + + ST      P     
Sbjct: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK--------SKIGSTENLKHQPG---- 242

Query: 832 KKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKA 891
                    GK   + K        DLS  +S   S         G   +  +V   V  
Sbjct: 243 --------GGKVQIINK------KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDL 286

Query: 892 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPG 950
           + + S+  +   I  KP   +    + +L          D K+ V+SK+GS +NI H PG
Sbjct: 287 SKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVPG 336

Query: 951 GGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988
           GG  K+E  K T       K +  A      P+ S    P
Sbjct: 337 GGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 376



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)

Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
           D P L +  A  V    M +++++ G   D       D     A     +P    G    
Sbjct: 81  DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 139

Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
             +PA+          + P +S     S + SG + P  G P   GT    +  P+   P
Sbjct: 140 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 189

Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
           P+ E K   +  T P   S++K++ Q   +P
Sbjct: 190 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 220


>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
            sapiens]
          Length = 383

 Score =  184 bits (468), Expect = 3e-46
 Identities = 119/291 (40%), Positives = 149/291 (51%), Gaps = 62/291 (21%)

Query: 801  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLS 859
            +K      K  T    A  G   ++ +T +P K P A KT     E  K   +S     S
Sbjct: 84   AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYS 140

Query: 860  RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 919
             P S  T   +  T    T P        V  TP            K P+SAK       
Sbjct: 141  SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK------- 182

Query: 920  LSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTA 978
             SRL T     PDLKNV+SK+GSTEN+KHQPGGG                          
Sbjct: 183  -SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG-------------------------- 215

Query: 979  GPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSK 1038
                        KVQI++KK+  S++QSKCGSKDNIKHVPGGG+VQI  K VD+SKV+SK
Sbjct: 216  ------------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSK 263

Query: 1039 CGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
            CGS  NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 264  CGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 314



 Score =  110 bits (274), Expect = 1e-23
 Identities = 87/293 (29%), Positives = 120/293 (40%), Gaps = 81/293 (27%)

Query: 779  AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 838
            AK P    +P  P+S    +SG +S  +   +       S  PS  +P T  PKK   ++
Sbjct: 115  AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172

Query: 839  TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 898
            T  K     K   ++ P  +   K+                              + S+ 
Sbjct: 173  TPPKSPSSAKSRLQTAPVPMPDLKN------------------------------VKSKI 202

Query: 899  STTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEK 958
             +T  +  +P   K      +L          DL NV+SK GS +NIKH PGGG      
Sbjct: 203  GSTENLKHQPGGGKVQIINKKL----------DLSNVQSKCGSKDNIKHVPGGG------ 246

Query: 959  KTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVP 1018
                                             VQIV K V  S + SKCGS  NI H P
Sbjct: 247  --------------------------------SVQIVYKPVDLSKVTSKCGSLGNIHHKP 274

Query: 1019 GGGNVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 1070
            GGG V+++++K+D   +V SK GS  NI H PGGG+ KIE+ KL F+E A+AK
Sbjct: 275  GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 327



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 53/317 (16%)

Query: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737
           GTG+D       +     + KTK +AT + A     K +   T +P +  PAP T     
Sbjct: 76  GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128

Query: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP--ASA 794
           + P S   SG      P  P   S  PS+      +PK +A  + P K  S +K    +A
Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 188

Query: 795 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 854
           P      K+ +        + + ST      P              GK   + K      
Sbjct: 189 PVPMPDLKNVK--------SKIGSTENLKHQPG------------GGKVQIINK------ 222

Query: 855 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 914
             DLS  +S   S         G   +  +V   V  + + S+  +   I  KP   +  
Sbjct: 223 KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE 280

Query: 915 STTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPES 971
             + +L          D K+ V+SK+GS +NI H PGGG  K+E  K T       K + 
Sbjct: 281 VKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDH 330

Query: 972 NAVTKTAGPIASAQKQP 988
            A      P+ S    P
Sbjct: 331 GAEIVYKSPVVSGDTSP 347



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)

Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
           D P L +  A  V    M +++++ G   D       D     A     +P    G    
Sbjct: 52  DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110

Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
             +PA+          + P +S     S + SG + P  G P   GT    +  P+   P
Sbjct: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160

Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
           P+ E K   +  T P   S++K++ Q   +P
Sbjct: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191


>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
          Length = 1827

 Score =  147 bits (371), Expect = 6e-35
 Identities = 209/849 (24%), Positives = 337/849 (39%), Gaps = 149/849 (17%)

Query: 299  DMALVKDMELPTE--KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETER 356
            + AL KD+ +PT+   E A       P   +V  +K V    +  V    DV +    + 
Sbjct: 997  EQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPSKKVEQGLDFAVQGQLDVKISDFGQM 1056

Query: 357  ASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVP---AKDLVLL 413
            AS + +D   + ++             +P + D     + G  KE   V     K+ V  
Sbjct: 1057 ASGLNIDDRRATELKLEATQDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK 1116

Query: 414  SEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVA 473
             ++   +A D   S E SS E  +L+ E+  A        PE+++I         + E+A
Sbjct: 1117 PDLVHQEAVDKEESYE-SSGEHESLTMESLKADEGKKETSPESSLI---------QDEIA 1166

Query: 474  PVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKN 533
             VK   ++P        D+A     +V +     P  E++      +TP    E +    
Sbjct: 1167 -VKLSVEIPCPPAVSEADLATDERADVQMEFIQGPKEESKETPDISITPSDVAEPLHETI 1225

Query: 534  VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDME 593
            V  P E++    E +      +     D +      V+ A+      E      P +   
Sbjct: 1226 VSEPAEIQSEEEEIEAQGEYDKLLFRSDTLQITDLGVSGAR------EEFVETCPSEHKG 1279

Query: 594  IAQTQKGISED--SHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGER 651
            + ++   I +D  + +++  D G+S + +   +        ++ S   EE+  +E+  E 
Sbjct: 1280 VIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEVERRPSPHDEEEFEVEEAAEA 1339

Query: 652  K--PCNSQP-------------SELSSETSGIARPE--------EGRPVVSGTGNDITTP 688
            +  P +  P             SE  +ET    + E        +   +   T +D  + 
Sbjct: 1340 QAEPKDGSPEAPASPEREEVALSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSI 1399

Query: 689  PNKELP--PSPEKKTKPLATT--------QPAKTSTSKAKTQPTSLPKQPAPTTIG---- 734
              ++L   P  EK  K    +        +P KT   +  T    + K+  P+T+     
Sbjct: 1400 MTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRISTPERKVAKKE-PSTVSRDEV 1458

Query: 735  ----GLNKKPMSLASGLVPAAPPKR-----PAVASARPSIL-----------------PS 768
                 + KK        V A  P R     PA+   RP+ L                 PS
Sbjct: 1459 RRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPS 1518

Query: 769  --KDVKPKPIADA--KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSR 824
              K  K K ++D   K+PEKR+S  +P+S    R G    +     +  ++++S+   + 
Sbjct: 1519 VFKQAKDK-VSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTT 1577

Query: 825  SPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR-PKSTSTSSMKKTTTLSGTAPAAG 883
                +     +   T   P     +T  + P+  SR P +  T S  +T    GT  +A 
Sbjct: 1578 RSEPIRRAGKSGTSTPTTPGSTA-ITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAI 1636

Query: 884  VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943
            +VPS  K   + + P               S  TP+  RL  N   PDLKNV+SK+GST+
Sbjct: 1637 LVPSEKKVAIIRTPPK--------------SPATPKQLRLI-NQPLPDLKNVKSKIGSTD 1681

Query: 944  NIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSH 1003
            NIK+QP GG+                                      VQIV+KK+  SH
Sbjct: 1682 NIKYQPKGGQ--------------------------------------VQIVTKKIDLSH 1703

Query: 1004 IQSKCGSKDNIKHVPGGGNVQIQNKKVDIS-KVSSKCGSKANIKHKPGGGDVKIESQKLN 1062
            + SKCGS  NI+H PGGG V+I++ K+D   K  +K GS  N  H PGGG+VKI+SQKLN
Sbjct: 1704 VTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLN 1763

Query: 1063 FKEKAQAKV 1071
            F+E A+A+V
Sbjct: 1764 FREHAKARV 1772


>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sapiens]
          Length = 471

 Score =  140 bits (353), Expect = 7e-33
 Identities = 117/351 (33%), Positives = 159/351 (45%), Gaps = 94/351 (26%)

Query: 748  VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 794
            +P +PP  PA          A    ++ PS  K  K K ++D   K+PEKR+S  +P+S 
Sbjct: 133  LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191

Query: 795  PASRSG-------------SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG 841
               R G             S  + +  +TT +  +   G S  S  T      TAI T G
Sbjct: 192  LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPT--TPGSTAI-TPG 248

Query: 842  KPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT 901
             P      T          P +  T S  +T    GT  +A +VPS  K   + + P   
Sbjct: 249  TPPSYSSRT----------PGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK-- 296

Query: 902  PFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTE 961
                        S  TP+  RL  N   PDLKNV+SK+GST+NIK+QP GG+ ++     
Sbjct: 297  ------------SPATPKQLRL-INQPLPDLKNVKSKIGSTDNIKYQPKGGQVQI----- 338

Query: 962  AAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 1021
                        VTK                     K+  SH+ SKCGS  NI+H PGGG
Sbjct: 339  ------------VTK---------------------KIDLSHVTSKCGSLKNIRHRPGGG 365

Query: 1022 NVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKV 1071
             V+I++ K+D   K  +K GS  N  H PGGG+VKI+SQKLNF+E A+A+V
Sbjct: 366  RVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARV 416



 Score =  128 bits (322), Expect = 3e-29
 Identities = 109/327 (33%), Positives = 145/327 (44%), Gaps = 69/327 (21%)

Query: 781  APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 840
            A E    P  P  +PAS             T     A+ G S+ +PS     K     ++
Sbjct: 127  AEETANLPPSPPPSPASEQ-----------TVTVEEAAGGESALAPSVFKQAKDKV--SD 173

Query: 841  GKPAEVKKMTAKSVPADLSRPK--------------STSTSSMKKTTTLSGTAPAAGVVP 886
            G     +K ++   P+ +  P+              ++S SS  + TT S     AG   
Sbjct: 174  GVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGK-- 231

Query: 887  SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 946
                 T  P+ P +T      P S   SS TP      +    P                
Sbjct: 232  ---SGTSTPTTPGSTAITPGTPPSY--SSRTPGTPGTPSYPRTP---------------- 270

Query: 947  HQPGGGRAKV----EKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYS 1002
            H PG  ++ +    EKK     T   P+S A  K    I     QP   ++         
Sbjct: 271  HTPGTPKSAILVPSEKKVAIIRTP--PKSPATPKQLRLI----NQPLPDLK--------- 315

Query: 1003 HIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLN 1062
            +++SK GS DNIK+ P GG VQI  KK+D+S V+SKCGS  NI+H+PGGG VKIES KL+
Sbjct: 316  NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLD 375

Query: 1063 FKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
            FKEKAQAKVGSLDN  H+P GG VK +
Sbjct: 376  FKEKAQAKVGSLDNAHHVPGGGNVKID 402


>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
            sapiens]
          Length = 352

 Score =  128 bits (321), Expect = 4e-29
 Identities = 85/236 (36%), Positives = 118/236 (50%), Gaps = 26/236 (11%)

Query: 858  LSRPKSTSTSSMKKTTTLSGTAPAA---GVVPSRVKATPMPSR-PSTTPFIDKKPTSAKP 913
            +S+ K  + S  KK     G    A   G  P   K     +R P+ TP   K P    P
Sbjct: 70   VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----P 125

Query: 914  SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973
            SS  P  S   +  S+P           T ++   P                TR+P+  A
Sbjct: 126  SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----------------TREPKKVA 169

Query: 974  VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033
            V +T     S+ K       +    +   +++SK GS +N+KH PGGG VQI  K VD+S
Sbjct: 170  VVRTPPKSPSSAKSRLQTAPVPMPDLK--NVKSKIGSTENLKHQPGGGKVQIVYKPVDLS 227

Query: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
            KV+SKCGS  NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 228  KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 60/221 (27%), Positives = 88/221 (39%), Gaps = 30/221 (13%)

Query: 779 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 838
           AK P    +P  P+S    +SG +S  +   +       S  PS  +P T  PKK   ++
Sbjct: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172

Query: 839 TEGKPAEVKKMTAKSVPA---DLSRPKST--STSSMKKTTTLSGTAPAAG---VVPSRVK 890
           T  K     K   ++ P    DL   KS   ST ++K         P  G   +V   V 
Sbjct: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH-------QPGGGKVQIVYKPVD 225

Query: 891 ATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQP 949
            + + S+  +   I  KP   +    + +L          D K+ V+SK+GS +NI H P
Sbjct: 226 LSKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVP 275

Query: 950 GGGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988
           GGG  K+E  K T       K +  A      P+ S    P
Sbjct: 276 GGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 316



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 10/114 (8%)

Query: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737
           GTG+D       +     + KTK +AT + A     K +   T +P +  PAP T     
Sbjct: 76  GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128

Query: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK 790
           + P S   SG      P  P   S  PS+      +PK +A  + P K  S +K
Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 182



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)

Query: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
           D P L +  A  V    M +++++ G   D       D     A     +P    G    
Sbjct: 52  DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110

Query: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
             +PA+          + P +S     S + SG + P  G P   GT    +  P+   P
Sbjct: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160

Query: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
           P+ E K   +  T P   S++K++ Q   +P
Sbjct: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  115 bits (288), Expect = 2e-25
 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%)

Query: 253  SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312
            SKET + + K+  + TK      K   +  K   T AK+ Q S+E   A  KD+  PT K
Sbjct: 137  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 192

Query: 313  EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371
             +A       PT    ++ K   L T  E  P         T +  +P  +  AP+    
Sbjct: 193  VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 242

Query: 372  PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431
             PKE    T +++P             PKE      K+    +  E A            
Sbjct: 243  TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 280

Query: 432  SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489
            +  K    + T+ A     T P E      K  A     E AP       P T   PA  
Sbjct: 281  TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336

Query: 490  -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548
             K+ AP+T KE        P   T           P        +   P E     T+  
Sbjct: 337  TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396

Query: 549  VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607
                K  AP       T     +P     P   T   P P    + A  T K  +  +  
Sbjct: 397  PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456

Query: 608  ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661
            E      +  APT    P      ET   T KK +    E   L      KP  + P EL
Sbjct: 457  EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 514

Query: 662  SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713
            +  T     PEE  P         TTP    PN    P+P    +P  TT  +PA T+  
Sbjct: 515  APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568

Query: 714  ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759
                T+   T PT+L       PK+PAP  +     K+P S          PK   P   
Sbjct: 569  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628

Query: 760  SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819
                   P +     P   A    K  +P+ P   PA +  + +T     +TT+   A T
Sbjct: 629  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 820  GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879
             P   +P+T  PK+P A  T  KPA     T     +++S P +T     K+ TT+  + 
Sbjct: 688  TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 739

Query: 880  PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939
              +      + A P P     +P     PT+  P++T P ++     T+A D    R   
Sbjct: 740  DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 788

Query: 940  GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999
                +++  P    A  +   E A TT K   + +T T   + S   Q     +I + K 
Sbjct: 789  ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844

Query: 1000 S 1000
            +
Sbjct: 845  T 845



 Score =  105 bits (263), Expect = 2e-22
 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%)

Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245
           H++   SP+   A+P  P+P+  P         L + KE  + ++E           G  
Sbjct: 109 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 168

Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304
           KTT    ++  E   AKD+A  +K         E+ TK   +T  K+  P+   + A   
Sbjct: 169 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 228

Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345
             E            P E      K     P E   ++ K     T  E AP        
Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288

Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398
                  T  KE    +P K      K+  P  PKE    T +  +P   + AP+    P
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348

Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446
                       PKE      K+    +  E +       +   + +             
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502
               T P E +   TK+ A     E AP       P T   PA    K+ AP+T K+   
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 465

Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562
               +P +  E A     T P ET     K +      ++A T  + PA  T   LA   
Sbjct: 466 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 516

Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622
                   TP +  P   E  A   P        T K  +  +  E      +  APT  
Sbjct: 517 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 565

Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682
            +P+    T  K + P    + L++     P    P EL+  T+         P  +   
Sbjct: 566 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 613

Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
               T P    P +P+   +P  TT      T+   T PT+L K+PAPTT     KKP  
Sbjct: 614 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 663

Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801
               L P       +  S +P+    K+  P  P   A    K+ +P+ P + P + S  
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723

Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861
            +  T  + TT        P   +P   L  +PT    E  P E    T K+  A  ++P
Sbjct: 724 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 775

Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917
           + T+T+  K T   L  T       P   K T   +  +T   I     + TS     TT
Sbjct: 776 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 835

Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
           P +++ L T T AP +   +  + +TE I ++P       ++ T + ATT KP+
Sbjct: 836 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 888



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%)

Query: 192 VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251
           V A  +P +E+     A+  P +PT  P    +      +E  P           T   A
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 240

Query: 252 PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311
           P+   E A     +  T  +       + P     T  K+  P+   + A       PT 
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 297

Query: 312 KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371
            +       + P  T             T   P +     KE    +P   + AP+    
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 355

Query: 372 PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429
           P     KE    +P +     +K+  P  PKE    PA      +     +     + + 
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 411

Query: 430 ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489
            ++ ++ + ++  E A     T P E      K  A     E AP       P T   PA
Sbjct: 412 PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467

Query: 490 ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543
               K+ AP+T KE      K ++P +  ++A      P P T          P E+   
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 517

Query: 544 LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600
             E+  P    E AP   K           P     P   T   P P    E A T  KG
Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577

Query: 601 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659
            +  +  E      +  AP  +    T   T   C  PA            ++P  + P 
Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637

Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719
           E +  T     P   +     T      P  KEL P+  K   P +TT      T+  +T
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 692

Query: 720 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766
            PT+ PK+PAPTT     KKP    +   P  PP            K P      P    
Sbjct: 693 APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743

Query: 767 PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800
           P    +P P A   +P++   P+                           P +  A+   
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803

Query: 801 SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854
           +K T T  + TT + + +T     S +T    P K T +KT     +V    K +T   +
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863

Query: 855 ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908
              P + ++PK  +T+S  K TT     P     P +  +T    +P T P + K    P
Sbjct: 864 MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 916

Query: 909 TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963
           T  K +ST P L+        P  +   + + +T      P     +V  K+E A
Sbjct: 917 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 963



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%)

Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744
           PPN +             T +  +T+T+  +T      K  +      + K   K ++  
Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 190

Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804
           S ++    PK            P +     P   A    K  +P+   SAP +      T
Sbjct: 191 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 250

Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862
            T +  TT    A T  +++ P+   PK+P    T+ +PA     +A + P +   + PK
Sbjct: 251 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 307

Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919
             + ++ K+   TT     P     P+     P P+ P    P   KKP    P    P 
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367

Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979
             +    T+  +      K  +    K  P   +      T++A TT K  S   TK   
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427

Query: 980 PIASAQKQPA 989
           P  +  K+PA
Sbjct: 428 P--TTPKEPA 435


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  115 bits (288), Expect = 2e-25
 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%)

Query: 253  SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312
            SKET + + K+  + TK      K   +  K   T AK+ Q S+E   A  KD+  PT K
Sbjct: 178  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 233

Query: 313  EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371
             +A       PT    ++ K   L T  E  P         T +  +P  +  AP+    
Sbjct: 234  VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 283

Query: 372  PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431
             PKE    T +++P             PKE      K+    +  E A            
Sbjct: 284  TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 321

Query: 432  SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489
            +  K    + T+ A     T P E      K  A     E AP       P T   PA  
Sbjct: 322  TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377

Query: 490  -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548
             K+ AP+T KE        P   T           P        +   P E     T+  
Sbjct: 378  TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437

Query: 549  VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607
                K  AP       T     +P     P   T   P P    + A  T K  +  +  
Sbjct: 438  PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497

Query: 608  ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661
            E      +  APT    P      ET   T KK +    E   L      KP  + P EL
Sbjct: 498  EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 555

Query: 662  SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713
            +  T     PEE  P         TTP    PN    P+P    +P  TT  +PA T+  
Sbjct: 556  APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609

Query: 714  ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759
                T+   T PT+L       PK+PAP  +     K+P S          PK   P   
Sbjct: 610  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669

Query: 760  SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819
                   P +     P   A    K  +P+ P   PA +  + +T     +TT+   A T
Sbjct: 670  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 820  GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879
             P   +P+T  PK+P A  T  KPA     T     +++S P +T     K+ TT+  + 
Sbjct: 729  TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 780

Query: 880  PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939
              +      + A P P     +P     PT+  P++T P ++     T+A D    R   
Sbjct: 781  DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 829

Query: 940  GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999
                +++  P    A  +   E A TT K   + +T T   + S   Q     +I + K 
Sbjct: 830  ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885

Query: 1000 S 1000
            +
Sbjct: 886  T 886



 Score =  105 bits (263), Expect = 2e-22
 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%)

Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245
           H++   SP+   A+P  P+P+  P         L + KE  + ++E           G  
Sbjct: 150 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 209

Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304
           KTT    ++  E   AKD+A  +K         E+ TK   +T  K+  P+   + A   
Sbjct: 210 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 269

Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345
             E            P E      K     P E   ++ K     T  E AP        
Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329

Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398
                  T  KE    +P K      K+  P  PKE    T +  +P   + AP+    P
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389

Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446
                       PKE      K+    +  E +       +   + +             
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502
               T P E +   TK+ A     E AP       P T   PA    K+ AP+T K+   
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 506

Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562
               +P +  E A     T P ET     K +      ++A T  + PA  T   LA   
Sbjct: 507 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 557

Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622
                   TP +  P   E  A   P        T K  +  +  E      +  APT  
Sbjct: 558 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 606

Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682
            +P+    T  K + P    + L++     P    P EL+  T+         P  +   
Sbjct: 607 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 654

Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
               T P    P +P+   +P  TT      T+   T PT+L K+PAPTT     KKP  
Sbjct: 655 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 704

Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801
               L P       +  S +P+    K+  P  P   A    K+ +P+ P + P + S  
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764

Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861
            +  T  + TT        P   +P   L  +PT    E  P E    T K+  A  ++P
Sbjct: 765 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 816

Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917
           + T+T+  K T   L  T       P   K T   +  +T   I     + TS     TT
Sbjct: 817 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 876

Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
           P +++ L T T AP +   +  + +TE I ++P       ++ T + ATT KP+
Sbjct: 877 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 929



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%)

Query: 192  VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251
            V A  +P +E+     A+  P +PT  P    +      +E  P           T   A
Sbjct: 234  VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 281

Query: 252  PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311
            P+   E A     +  T  +       + P     T  K+  P+   + A       PT 
Sbjct: 282  PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 338

Query: 312  KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371
             +       + P  T             T   P +     KE    +P   + AP+    
Sbjct: 339  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 396

Query: 372  PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429
            P     KE    +P +     +K+  P  PKE    PA      +     +     + + 
Sbjct: 397  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 452

Query: 430  ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489
             ++ ++ + ++  E A     T P E      K  A     E AP       P T   PA
Sbjct: 453  PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508

Query: 490  ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543
                K+ AP+T KE      K ++P +  ++A      P P T          P E+   
Sbjct: 509  PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 558

Query: 544  LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600
              E+  P    E AP   K           P     P   T   P P    E A T  KG
Sbjct: 559  TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618

Query: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659
             +  +  E      +  AP  +    T   T   C  PA            ++P  + P 
Sbjct: 619  TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678

Query: 660  ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719
            E +  T     P   +     T      P  KEL P+  K   P +TT      T+  +T
Sbjct: 679  EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 733

Query: 720  QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766
             PT+ PK+PAPTT     KKP    +   P  PP            K P      P    
Sbjct: 734  APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784

Query: 767  PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800
            P    +P P A   +P++   P+                           P +  A+   
Sbjct: 785  PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844

Query: 801  SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854
            +K T T  + TT + + +T     S +T    P K T +KT     +V    K +T   +
Sbjct: 845  TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904

Query: 855  ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908
               P + ++PK  +T+S  K TT     P     P +  +T    +P T P + K    P
Sbjct: 905  MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 957

Query: 909  TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963
            T  K +ST P L+        P  +   + + +T      P     +V  K+E A
Sbjct: 958  TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1004



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%)

Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744
           PPN +             T +  +T+T+  +T      K  +      + K   K ++  
Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 231

Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804
           S ++    PK            P +     P   A    K  +P+   SAP +      T
Sbjct: 232 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 291

Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862
            T +  TT    A T  +++ P+   PK+P    T+ +PA     +A + P +   + PK
Sbjct: 292 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 348

Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919
             + ++ K+   TT     P     P+     P P+ P    P   KKP    P    P 
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408

Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979
             +    T+  +      K  +    K  P   +      T++A TT K  S   TK   
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468

Query: 980 PIASAQKQPA 989
           P  +  K+PA
Sbjct: 469 P--TTPKEPA 476


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  115 bits (288), Expect = 2e-25
 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%)

Query: 253  SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312
            SKET + + K+  + TK      K   +  K   T AK+ Q S+E   A  KD+  PT K
Sbjct: 230  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 285

Query: 313  EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371
             +A       PT    ++ K   L T  E  P         T +  +P  +  AP+    
Sbjct: 286  VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 335

Query: 372  PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431
             PKE    T +++P             PKE      K+    +  E A            
Sbjct: 336  TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 373

Query: 432  SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489
            +  K    + T+ A     T P E      K  A     E AP       P T   PA  
Sbjct: 374  TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 490  -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548
             K+ AP+T KE        P   T           P        +   P E     T+  
Sbjct: 430  TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489

Query: 549  VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607
                K  AP       T     +P     P   T   P P    + A  T K  +  +  
Sbjct: 490  PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549

Query: 608  ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661
            E      +  APT    P      ET   T KK +    E   L      KP  + P EL
Sbjct: 550  EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 607

Query: 662  SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713
            +  T     PEE  P         TTP    PN    P+P    +P  TT  +PA T+  
Sbjct: 608  APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661

Query: 714  ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759
                T+   T PT+L       PK+PAP  +     K+P S          PK   P   
Sbjct: 662  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 760  SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819
                   P +     P   A    K  +P+ P   PA +  + +T     +TT+   A T
Sbjct: 722  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 820  GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879
             P   +P+T  PK+P A  T  KPA     T     +++S P +T     K+ TT+  + 
Sbjct: 781  TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 832

Query: 880  PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939
              +      + A P P     +P     PT+  P++T P ++     T+A D    R   
Sbjct: 833  DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 881

Query: 940  GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999
                +++  P    A  +   E A TT K   + +T T   + S   Q     +I + K 
Sbjct: 882  ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 937

Query: 1000 S 1000
            +
Sbjct: 938  T 938



 Score =  105 bits (263), Expect = 2e-22
 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%)

Query: 199 HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245
           H++   SP+   A+P  P+P+  P         L + KE  + ++E           G  
Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261

Query: 246 KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304
           KTT    ++  E   AKD+A  +K         E+ TK   +T  K+  P+   + A   
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321

Query: 305 DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345
             E            P E      K     P E   ++ K     T  E AP        
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 346 ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398
                  T  KE    +P K      K+  P  PKE    T +  +P   + AP+    P
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441

Query: 399 ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446
                       PKE      K+    +  E +       +   + +             
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 447 ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502
               T P E +   TK+ A     E AP       P T   PA    K+ AP+T K+   
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 558

Query: 503 LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562
               +P +  E A     T P ET     K +      ++A T  + PA  T   LA   
Sbjct: 559 ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 609

Query: 563 VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622
                   TP +  P   E  A   P        T K  +  +  E      +  APT  
Sbjct: 610 -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 658

Query: 623 ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682
            +P+    T  K + P    + L++     P    P EL+  T+         P  +   
Sbjct: 659 -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 706

Query: 683 NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
               T P    P +P+   +P  TT      T+   T PT+L K+PAPTT     KKP  
Sbjct: 707 KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 756

Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801
               L P       +  S +P+    K+  P  P   A    K+ +P+ P + P + S  
Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816

Query: 802 KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861
            +  T  + TT        P   +P   L  +PT    E  P E    T K+  A  ++P
Sbjct: 817 STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 868

Query: 862 KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917
           + T+T+  K T   L  T       P   K T   +  +T   I     + TS     TT
Sbjct: 869 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928

Query: 918 P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
           P +++ L T T AP +   +  + +TE I ++P       ++ T + ATT KP+
Sbjct: 929 PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 981



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%)

Query: 192  VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251
            V A  +P +E+     A+  P +PT  P    +      +E  P           T   A
Sbjct: 286  VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 333

Query: 252  PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311
            P+   E A     +  T  +       + P     T  K+  P+   + A       PT 
Sbjct: 334  PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 390

Query: 312  KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371
             +       + P  T             T   P +     KE    +P   + AP+    
Sbjct: 391  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 448

Query: 372  PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429
            P     KE    +P +     +K+  P  PKE    PA      +     +     + + 
Sbjct: 449  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 504

Query: 430  ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489
             ++ ++ + ++  E A     T P E      K  A     E AP       P T   PA
Sbjct: 505  PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560

Query: 490  ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543
                K+ AP+T KE      K ++P +  ++A      P P T          P E+   
Sbjct: 561  PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 610

Query: 544  LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600
              E+  P    E AP   K           P     P   T   P P    E A T  KG
Sbjct: 611  TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670

Query: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659
             +  +  E      +  AP  +    T   T   C  PA            ++P  + P 
Sbjct: 671  TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730

Query: 660  ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719
            E +  T     P   +     T      P  KEL P+  K   P +TT      T+  +T
Sbjct: 731  EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 785

Query: 720  QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766
             PT+ PK+PAPTT     KKP    +   P  PP            K P      P    
Sbjct: 786  APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836

Query: 767  PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800
            P    +P P A   +P++   P+                           P +  A+   
Sbjct: 837  PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896

Query: 801  SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854
            +K T T  + TT + + +T     S +T    P K T +KT     +V    K +T   +
Sbjct: 897  TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 956

Query: 855  ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908
               P + ++PK  +T+S  K TT     P     P +  +T    +P T P + K    P
Sbjct: 957  MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 1009

Query: 909  TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963
            T  K +ST P L+        P  +   + + +T      P     +V  K+E A
Sbjct: 1010 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%)

Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744
           PPN +             T +  +T+T+  +T      K  +      + K   K ++  
Sbjct: 224 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283

Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804
           S ++    PK            P +     P   A    K  +P+   SAP +      T
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343

Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862
            T +  TT    A T  +++ P+   PK+P    T+ +PA     +A + P +   + PK
Sbjct: 344 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 400

Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919
             + ++ K+   TT     P     P+     P P+ P    P   KKP    P    P 
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460

Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979
             +    T+  +      K  +    K  P   +      T++A TT K  S   TK   
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520

Query: 980 PIASAQKQPA 989
           P  +  K+PA
Sbjct: 521 P--TTPKEPA 528


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  115 bits (288), Expect = 2e-25
 Identities = 191/781 (24%), Positives = 272/781 (34%), Gaps = 105/781 (13%)

Query: 253  SKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEK 312
            SKET + + K+  + TK      K   +  K   T AK+ Q S+E   A  KD+  PT K
Sbjct: 271  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSA--KDL-APTSK 326

Query: 313  EVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET-ERASPIKMDLAPSKDMG 371
             +A       PT    ++ K   L T  E  P         T +  +P  +  AP+    
Sbjct: 327  VLAK------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT---- 376

Query: 372  PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEIS 431
             PKE    T +++P             PKE      K+    +  E A            
Sbjct: 377  TPKEPAPTTTKSAPT-----------TPKEPAPTTTKEPAPTTPKEPA-----------P 414

Query: 432  SAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA-- 489
            +  K    + T+ A     T P E      K  A     E AP       P T   PA  
Sbjct: 415  TTTKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 490  -KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548
             K+ AP+T KE        P   T           P        +   P E     T+  
Sbjct: 471  TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530

Query: 549  VPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIA-QTQKGISEDSHL 607
                K  AP       T     +P     P   T   P P    + A  T K  +  +  
Sbjct: 531  PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590

Query: 608  ESLQDVGQSAAPTFMISP------ETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSEL 661
            E      +  APT    P      ET   T KK +    E   L      KP  + P EL
Sbjct: 591  EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK--LAPTTPEKPAPTTPEEL 648

Query: 662  SSETSGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATT--QPAKTS-- 713
            +  T     PEE  P         TTP    PN    P+P    +P  TT  +PA T+  
Sbjct: 649  APTT-----PEEPTPTTPEEPAP-TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702

Query: 714  ----TSKAKTQPTSL-------PKQPAPTTIG-GLNKKPMSLASGLVPAAPPK--RPAVA 759
                T+   T PT+L       PK+PAP  +     K+P S          PK   P   
Sbjct: 703  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 760  SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819
                   P +     P   A    K  +P+ P   PA +  + +T     +TT+   A T
Sbjct: 763  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 820  GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879
             P   +P+T  PK+P A  T  KPA     T     +++S P +T     K+ TT+  + 
Sbjct: 822  TPKETAPTT--PKEP-APTTPKKPAPTTPETPPPTTSEVSTPTTT-----KEPTTIHKSP 873

Query: 880  PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV 939
              +      + A P P     +P     PT+  P++T P ++     T+A D    R   
Sbjct: 874  DES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-----TTAKDKTTER--- 922

Query: 940  GSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKV 999
                +++  P    A  +   E A TT K   + +T T   + S   Q     +I + K 
Sbjct: 923  ----DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 978

Query: 1000 S 1000
            +
Sbjct: 979  T 979



 Score =  105 bits (263), Expect = 2e-22
 Identities = 196/834 (23%), Positives = 294/834 (35%), Gaps = 116/834 (13%)

Query: 199  HSESFVSPE-AVAEP--PQPTAVP---------LELAKEIEMASEERPPAQALEIMMGL- 245
            H++   SP+   A+P  P+P+  P         L + KE  + ++E           G  
Sbjct: 243  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302

Query: 246  KTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK-LDVTLAKDMQPSMESDMALVK 304
            KTT    ++  E   AKD+A  +K         E+ TK   +T  K+  P+   + A   
Sbjct: 303  KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362

Query: 305  DME-----------LPTEKEVALVKDV-RWPTETDVSSAKNVVLPTETEVAPA------- 345
              E            P E      K     P E   ++ K     T  E AP        
Sbjct: 363  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 346  ----KDVTLLKETERASPIKMDLAPSKDMGP--PKENKKET-ERASPIKMDLAPSKDMGP 398
                   T  KE    +P K      K+  P  PKE    T +  +P   + AP+    P
Sbjct: 423  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482

Query: 399  ------------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL 446
                        PKE      K+    +  E +       +   + +             
Sbjct: 483  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 447  ARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA----KDVAPSTVKEVGL 502
                T P E +   TK+ A     E AP       P T   PA    K+ AP+T K+   
Sbjct: 543  KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK--- 599

Query: 503  LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562
                +P +  E A     T P ET     K +      ++A T  + PA  T   LA   
Sbjct: 600  ---PAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-- 650

Query: 563  VLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622
                    TP +  P   E  A   P        T K  +  +  E      +  APT  
Sbjct: 651  -------TTPEEPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-- 699

Query: 623  ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG 682
             +P+    T  K + P    + L++     P    P EL+  T+         P  +   
Sbjct: 700  -TPKETAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTT-------KEPTSTTCD 747

Query: 683  NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
                T P    P +P+   +P  TT      T+   T PT+L K+PAPTT     KKP  
Sbjct: 748  KPAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT----PKKP-- 797

Query: 743  LASGLVPAAPPKRPAVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGS 801
                L P       +  S +P+    K+  P  P   A    K+ +P+ P + P + S  
Sbjct: 798  APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857

Query: 802  KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 861
             +  T  + TT        P   +P   L  +PT    E  P E    T K+  A  ++P
Sbjct: 858  STPTTTKEPTT----IHKSPDESTPE--LSAEPTPKALENSPKEPGVPTTKTPAA--TKP 909

Query: 862  KSTSTSSMKKT-TTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI---DKKPTSAKPSSTT 917
            + T+T+  K T   L  T       P   K T   +  +T   I     + TS     TT
Sbjct: 910  EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969

Query: 918  P-RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
            P +++ L T T AP +   +  + +TE I ++P       ++ T + ATT KP+
Sbjct: 970  PFKITTLKTTTLAPKVTTTKKTITTTE-IMNKPEETAKPKDRATNSKATTPKPQ 1022



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 184/835 (22%), Positives = 278/835 (33%), Gaps = 127/835 (15%)

Query: 192  VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMA 251
            V A  +P +E+     A+  P +PT  P    +      +E  P           T   A
Sbjct: 327  VLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPT----------TIKSA 374

Query: 252  PSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTE 311
            P+   E A     +  T  +       + P     T  K+  P+   + A       PT 
Sbjct: 375  PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTT 431

Query: 312  KEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371
             +       + P  T             T   P +     KE    +P   + AP+    
Sbjct: 432  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKK 489

Query: 372  PPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQANDIISSTE 429
            P     KE    +P +     +K+  P  PKE    PA      +     +     + + 
Sbjct: 490  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSAPTTTKEPAPTTTKSA 545

Query: 430  ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489
             ++ ++ + ++  E A     T P E      K  A     E AP       P T   PA
Sbjct: 546  PTTPKEPSPTTTKEPA----PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601

Query: 490  ----KDVAPSTVKEVGLL--KDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA 543
                K+ AP+T KE      K ++P +  ++A      P P T          P E+   
Sbjct: 602  PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----------PEELAPT 651

Query: 544  LTEDQVPALKTE-APLA-KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ-KG 600
              E+  P    E AP   K           P     P   T   P P    E A T  KG
Sbjct: 652  TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711

Query: 601  ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPS 659
             +  +  E      +  AP  +    T   T   C  PA            ++P  + P 
Sbjct: 712  TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771

Query: 660  ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719
            E +  T     P   +     T      P  KEL P+  K   P +TT      T+  +T
Sbjct: 772  EPAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKG--PTSTTSDKPAPTTPKET 826

Query: 720  QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP------------KRPAVASARPS-IL 766
             PT+ PK+PAPTT     KKP    +   P  PP            K P      P    
Sbjct: 827  APTT-PKEPAPTT----PKKP----APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877

Query: 767  PSKDVKPKPIADAKAPEKRASPSK--------------------------PASAPASRSG 800
            P    +P P A   +P++   P+                           P +  A+   
Sbjct: 878  PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937

Query: 801  SKSTQTVAKTTTAAAVASTGPSSRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV 854
            +K T T  + TT + + +T     S +T    P K T +KT     +V    K +T   +
Sbjct: 938  TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 997

Query: 855  ---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KP 908
               P + ++PK  +T+S  K TT     P     P +  +T    +P T P + K    P
Sbjct: 998  MNKPEETAKPKDRATNS--KATTPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTP 1050

Query: 909  TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAA 963
            T  K +ST P L+        P  +   + + +T      P     +V  K+E A
Sbjct: 1051 TPRKMTSTMPELN--------PTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 68/310 (21%), Positives = 111/310 (35%), Gaps = 13/310 (4%)

Query: 688 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK---KPMSLA 744
           PPN +             T +  +T+T+  +T      K  +      + K   K ++  
Sbjct: 265 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324

Query: 745 SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKST 804
           S ++    PK            P +     P   A    K  +P+   SAP +      T
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384

Query: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD--LSRPK 862
            T +  TT    A T  +++ P+   PK+P    T+ +PA     +A + P +   + PK
Sbjct: 385 TTKSAPTTPKEPAPT--TTKEPAPTTPKEPAPTTTK-EPAPTTTKSAPTTPKEPAPTTPK 441

Query: 863 STSTSSMKK--TTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTPR 919
             + ++ K+   TT     P     P+     P P+ P    P   KKP    P    P 
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501

Query: 920 LSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAG 979
             +    T+  +      K  +    K  P   +      T++A TT K  S   TK   
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561

Query: 980 PIASAQKQPA 989
           P  +  K+PA
Sbjct: 562 P--TTPKEPA 569


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 157/736 (21%), Positives = 270/736 (36%), Gaps = 93/736 (12%)

Query: 206   PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMA 265
             PE   +P     VP+   K++E      PPA+  E+   L   +  P+   +   A    
Sbjct: 10033 PEVPKKPVPEKKVPVPAPKKVEA-----PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK 10087

Query: 266   LATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTE 325
             +  K E         P  + V L ++ +   E ++   +++ LP E+EV   ++   P E
Sbjct: 10088 VPKKRE---------PVPVPVALPQEEEVLFEEEIVPEEEV-LPEEEEVLPEEEEVLPEE 10137

Query: 326   TDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGP-----PKENKKET 380
              +V   +  + P E EV P ++   + E E   P +  L   K   P     P+  KK T
Sbjct: 10138 EEVLPEEEEIPPEEEEVPPEEEY--VPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVT 10195

Query: 381   ER--ASPIKMDLAPSKDMGPPKENK----IVPAKDLVLLSEIEVAQANDIISSTEISSAE 434
             E+    P K +  P+K    PK+ +    I+P ++ VL  E+      + IS  EI   E
Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE-E 10254

Query: 435   KVALSSETEVALARDMTLPPETNVILTK-----DKALPLEAEVAPVKDMAQLPETEI--- 486
               ++    EVA       PP    ++ K        +P + E  P K   ++PE ++   
Sbjct: 10255 PPSIEEVEEVA-------PPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVP 10307

Query: 487   APAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTE 546
                K+  P+ V EV                 K V   PE +V++ K   +PP     + E
Sbjct: 10308 VQKKEAPPAKVPEVP----------------KKV---PEKKVLVPKKEAVPPAKGRTVLE 10348

Query: 547   DQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSH 606
             ++V     +  + K+  L L       +++P   E        ++ E  + ++ I  + H
Sbjct: 10349 EKVSVAFRQEVVVKER-LELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQH 10407

Query: 607   LESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETS 666
                 +   +       +         +K   P +   + EK+    P    P+++     
Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI---IPPKKPPTKVVPRKE 10464

Query: 667   GIAR-PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
               A+ PE  + +V      +  P    +PP+   +  P     P K    K    P   P
Sbjct: 10465 PPAKVPEVPKKIV--VEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK----KVPVPPAKKP 10518

Query: 726   KQPAPTTIGGLNKKPMSLA-SGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784
             + P P     + + P  +     VP  PPK+P V   +   +P   V  K + +A  P+ 
Sbjct: 10519 EAPPPK----VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP 10574

Query: 785   RASPSKPASAPASRSGSKSTQTV--AKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 842
              + P +   AP      K        K           P    P   +P  P   K E  
Sbjct: 10575 ESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPK-KPEVP 10633

Query: 843   PAEVKKMTAKSVP------ADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 896
             P +V ++   +VP      A   +P+S      ++   ++   P     P+ V   P P+
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP-----PAEVVEEPEPA 10688

Query: 897   RPSTTPFIDKKPTSAK 912
              P       KKP   K
Sbjct: 10689 APPQVTVPPKKPVPEK 10704



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 167/657 (25%), Positives = 253/657 (38%), Gaps = 125/657 (19%)

Query: 198   PHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETE 257
             P  +  V P  V E P+  AVP +   E      E PP +  E        ++ P K+  
Sbjct: 10542 PPKKPEVPPTKVPEVPK-AAVPEKKVPEAIPPKPESPPPEVPEA-----PKEVVPEKKVP 10595

Query: 258   MALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT----EKE 313
              A  K      K EV   K  E+P ++       + P  + ++   K  E+P     EK+
Sbjct: 10596 AAPPK------KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649

Query: 314   V--ALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMG 371
             V  A+      P        + V L    E  PA+   +++E E A+P ++ + P K   
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVAL----EEPPAE---VVEEPEPAAPPQVTVPPKK--- 10699

Query: 372   PPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKD--LVLLSEIEVAQANDIISSTE 429
             P  E K     A   K +L P K    PKE  +VP K   LV+  + E   A       E
Sbjct: 10700 PVPEKKAPAVVAK--KPELPPVKVPEVPKE--VVPEKKVPLVVPKKPEAPPAKVPEVPKE 10755

Query: 430   ISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPL-EAEVAPVKDMAQLPETEIAP 488
             +   +KVA+  + EV  A+   +P +   +L +  A+P+ E   +P  ++ + PE EIAP
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKP--VLEEKPAVPVPERAESPPPEVYEEPE-EIAP 10812

Query: 489   AKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ 548
              +++AP   K V       P++E E    +   PPP           +P E +  + E +
Sbjct: 10813 EEEIAPEEEKPV-------PVAEEE----EPEVPPP----------AVPEEPKKIIPEKK 10851

Query: 549   VPALKT-EAPLAKDGVLTLANNVTPAKDV--PPLSETEATPVPIKDMEIAQTQKGISEDS 605
             VP +K  EAP  K+          P K +  P L      P P    E  + +       
Sbjct: 10852 VPVIKKPEAPPPKEP--------EPEKVIEKPKLKPRPPPPPPAPPKEDVKEK------- 10896

Query: 606   HLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET 665
              +  L+ + +   P     PE V  T  K  +P  E  V + L ERKP   +   L S  
Sbjct: 10897 -IFQLKAIPKKKVPEKPQVPEKVELTPLK--VPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953

Query: 666   SGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ-PAKTSTSKAKTQPTSL 724
                 RPEE  P V     +    P    PP P    KP+   + P  T   +   +PT +
Sbjct: 10954 R--KRPEEEEPKVEPKKLEKVKKPAVPEPPPP----KPVEEVEVPTVTKRERKIPEPTKV 11007

Query: 725   PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784
             P+                    + PA P             LP+ + KPKP A+ K    
Sbjct: 11008 PE--------------------IKPAIP-------------LPAPEPKPKPEAEVKT--I 11032

Query: 785   RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTE 840
             +  P +P   P   +   +   V K   A A        + P   +PKK P+ I+ E
Sbjct: 11033 KPPPVEPEPTPI--AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAE 11087



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 196/899 (21%), Positives = 306/899 (34%), Gaps = 141/899 (15%)

Query: 151   DLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVA 210
             +++F      +  +   + + L +   + P    V+P+            E  + PE   
Sbjct: 10106 EVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE------------EEEIPPEEEE 10153

Query: 211   EPPQPTAVPLE--LAKEIEMASEERP----PAQALEIMMGLKTTDMAPSKETEMALAKDM 264
              PP+   VP E     E E+  E +P    PA   EI   +    +   K+ E   AK  
Sbjct: 10154 VPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVP 10213

Query: 265   ALATKTE---VALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR 321
              +  K E   + L K+ E    ++VT   + +P  E ++      E P+ +EV  V   R
Sbjct: 10214 EVPKKVEEKRIILPKE-EEVLPVEVTEEPEEEPISEEEIP----EEPPSIEEVEEVAPPR 10268

Query: 322   WPT--ETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKE 379
              P   +  V  A   V P + E  PAK    + E +   P++   AP   +    +   E
Sbjct: 10269 VPEVIKKAVPEAPTPV-PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE 10327

Query: 380   TERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLS---EIEV--AQANDIISSTEISSA- 433
              +   P K  + P+K     +E   V  +  V++    E+EV  A+  +I    E     
Sbjct: 10328 KKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387

Query: 434   -----------------EKVALSSETEVALARDM--TLPPETNVILTKDKALPLEAEVAP 474
                              E+  +  E  V     +      E   +  K KA P   E++ 
Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE 10447

Query: 475   VKDMAQLPETEIAPAKDVAPSTVKEVG---LLKD---------MSPLSETEMALGKDVTP 522
                  + P T++ P K+  P+ V EV    ++++         + P    E+   K+V P
Sbjct: 10448 KIIPPKKPPTKVVPRKE-PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP 10506

Query: 523   PPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG------VLTLANNVTPAKDV 576
               +  V   K    PP       ++ VP  K   P  K        V  +     P K V
Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566

Query: 577   P----PLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETV-TGT 631
             P    P  E+    VP    E+   +K  +       +  V    AP  ++  + V    
Sbjct: 10567 PEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626

Query: 632   GKKCSLPAEEDSVLEKLG--ERK-------PCNSQPSELSSETSGIARPEEGRPVVS--- 679
              KK  +P  +   + K+   E+K          S P E+  E   +A  E    VV    
Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE 10686

Query: 680   -GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK 738
                   +T PP K   P PEKK   +   +P        +  P  +P+ P       + +
Sbjct: 10687 PAAPPQVTVPPKK---PVPEKKAPAVVAKKP--------ELPPVKVPEVPKEV----VPE 10731

Query: 739   KPMSLASGLVPAAPPKRPAVASARPSILPSKDV---KPKPIADAKAPE---KRASPSKPA 792
             K + L     P APP +  V      ++P K V   K   +  AK PE   K     KPA
Sbjct: 10732 KKVPLVVPKKPEAPPAK--VPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789

Query: 793   SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKK-MTA 851
                  R+ S   +   +    A      P    P  +  ++   +     P E KK +  
Sbjct: 10790 VPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPE 10849

Query: 852   KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA 911
             K VP             +KK        P    V  + K  P P  P   P  +      
Sbjct: 10850 KKVPV------------IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKI 10897

Query: 912   KPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
                   P+          P+   V  KV  T      PGG     EKK       RKPE
Sbjct: 10898 FQLKAIPK-------KKVPEKPQVPEKVELTP--LKVPGG-----EKKVRKLLPERKPE 10942



 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 170/741 (22%), Positives = 273/741 (36%), Gaps = 92/741 (12%)

Query: 205   SPEAVAEPPQPT-AVPLELAKEIEMASEERPPAQALE----------IMMGLKTTDMAPS 253
             +P     P +P  AVP E   +++   EE PPA+  E          + +     +  P 
Sbjct: 9658  APPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI 9717

Query: 254   KETEMALAKDMALATKTE---VALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310
             KE  +   K+ A   + E   V   ++ E   + D    ++ +P+ E D       E   
Sbjct: 9718  KEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYD-----QYEEYE 9772

Query: 311   EKEVALVKD-VRWPTETD----VSSAKNVVLPTETEVAPAKDVTLLKETERAS---PIKM 362
             E+E    ++   + TE +    V       +PT+ +  PAK +      E+     P K+
Sbjct: 9773  EREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKL 9832

Query: 363   DLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGP--PKENKIVPAKDLVLLSEIEVAQ 420
                P K    PK+  +E  R S  K +     +     P + K V A++ V +   EVA 
Sbjct: 9833  KPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAP 9892

Query: 421   ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 480
                +    +    E+VA   E EV    +  L  E    + +++    E EV PV  + +
Sbjct: 9893  PVRVPEVPKELEPEEVAF--EEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPV-K 9949

Query: 481   LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEV-VLIKNVCLPPE 539
             +PE    P K V P   K V + K      E   A   +V   PE +V VLI     PP 
Sbjct: 9950  VPE---VPRKPV-PEEKKPVPVPKK----KEAPPAKVPEVPKKPEEKVPVLIPKKEKPPP 10001

Query: 540   MEV------ALTEDQVPA---LKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIK 590
              +V       + E++VP     K EAP AK  V  +     P K VP  +  +    P K
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAK--VPEVPKKPVPEKKVPVPAPKKVEAPPAK 10059

Query: 591   DMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEK--L 648
               E+   +K I E+     +    ++  P      E V       +LP EE+ + E+  +
Sbjct: 10060 VPEV--PKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP---VPVALPQEEEVLFEEEIV 10114

Query: 649   GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ 708
              E +    +   L  E   +   EE              P  +E+PP  E+         
Sbjct: 10115 PEEEVLPEEEEVLPEEEEVLPEEEE------------VLPEEEEIPPEEEEVPPEEEYVP 10162

Query: 709   PAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK------PMSLASGLVPAAPPKRPAVASAR 762
               +    + +  P   PK P P  +  + KK       +       PA  P+ P     +
Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222

Query: 763   PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 822
               ILP K+ +  P+   + PE+   P      P      +  + VA       +    P 
Sbjct: 10223 RIILP-KEEEVLPVEVTEEPEE--EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279

Query: 823   SRSPSTLLPKKPTAIKTEGKPAEV-KKMTAKSVPADLSR---PKSTSTSSMKKTTTLSGT 878
             + +P   +PK     K E  PA+V KK+  + VP  + +   P +      KK       
Sbjct: 10280 APTP---VPK-----KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL 10331

Query: 879   APAAGVVPSRVKATPMPSRPS 899
              P    VP     T +  + S
Sbjct: 10332 VPKKEAVPPAKGRTVLEEKVS 10352



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 116/543 (21%), Positives = 209/543 (38%), Gaps = 52/543 (9%)

Query: 204   VSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALA-- 261
             V  +AV E   P  +P +L        EE  P +  E  + +  T     + TE A    
Sbjct: 9814  VLKKAVPEEKVPVPIPKKLKPPPPKVPEE--PKKVFEEKIRISITKREKEQVTEPAAKVP 9871

Query: 262   -KDMALATKTEVALAKDMESPTKLDVTLAKDMQP---SMESDMALVKDMELPTEKEVALV 317
              K   +  + +V + +   +P      + K+++P   + E ++    +  L  E+E  + 
Sbjct: 9872  MKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIH 9931

Query: 318   KDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPK--- 374
             ++  + TE +V      V+P +    P K V      E   P+ +   P K   PP    
Sbjct: 9932  EEEEFITEEEVVP----VIPVKVPEVPRKPVP-----EEKKPVPV---PKKKEAPPAKVP 9979

Query: 375   ENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLS-EIEVAQANDIISSTEISSA 433
             E  K+ E   P+   L P K+  PP +   VP K +      + V +  +   +      
Sbjct: 9980  EVPKKPEEKVPV---LIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVP 10036

Query: 434   EKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVA 493
             +K     +  V   + +  PP   V     K +P E +  PV    + P  ++   ++  
Sbjct: 10037 KKPVPEKKVPVPAPKKVEAPP-AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPV 10095

Query: 494   PSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALK 553
             P  V    L ++   L E E+   ++V P  E EV+  +   LP E EV   E+++P  +
Sbjct: 10096 PVPV---ALPQEEEVLFEEEIVPEEEVLPEEE-EVLPEEEEVLPEEEEVLPEEEEIPPEE 10151

Query: 554   TEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDV 613
              E P  ++ V      V   + +P +      P P+ +++   T+K +      E     
Sbjct: 10152 EEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEE----- 10206

Query: 614   GQSAAPTFMISPETVTGTGKKCSLPAEEDSV---LEKLGERKPCNSQPSELSSETSGIAR 670
                 AP   +         K+  LP EE+ +   + +  E +P + +  E+  E   I  
Sbjct: 10207 ----APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEE--EIPEEPPSIEE 10260

Query: 671   PEEGRP-----VVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
              EE  P     V+     +  TP  K++   P K +K +   +       K +  P  +P
Sbjct: 10261 VEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKI-PEEKVPVPVQKKEAPPAKVP 10319

Query: 726   KQP 728
             + P
Sbjct: 10320 EVP 10322



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 158/767 (20%), Positives = 268/767 (34%), Gaps = 161/767 (20%)

Query: 209  VAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALAT 268
            V  PP P  +P           E++PP + +E+      T  A  K+ +  +AK   +  
Sbjct: 8960 VVAPPIPLLLPTP--------EEKKPPPKRIEV------TKKAVKKDAKKVVAKPKEMTP 9005

Query: 269  KTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDV 328
            + E+   K    PT L    A ++   + S    VK M +  +KEV   K+  +  +  V
Sbjct: 9006 REEIV--KKPPPPTTLIPAKAPEII-DVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAV 9062

Query: 329  SSAKNVVLPT------ETEVAPA----------------KDVTLLKETERASPIKMDLAP 366
               K V + +      E EV P                 +++ +  + E     + D   
Sbjct: 9063 HKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEE 9122

Query: 367  SKDMGPPKEN----KKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQAN 422
             ++    +E     ++E E A   +  +   K++      + VPAK    + E +     
Sbjct: 9123 GQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAK----VPEKKAPPPP 9178

Query: 423  DIISSTEISSAEKVALSSETEVALARDMTLPPETN--VILTKDKALPLEAEVAPVKDMAQ 480
             +I    I   EK +   E E      +T  PE +  ++  K    P++ EV  VK  A 
Sbjct: 9179 KVIKKPVIEKIEKTSRRMEEEKV---QVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAV 9235

Query: 481  LPETEIAPAKDV--APSTVKEVGLL-----KDMSPLSETEMALGKDVTPPPETEVVLIKN 533
              +  +   + +  A  T +EV +      K++    +  +A+ K V PPP+   +  K 
Sbjct: 9236 HTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEK- 9294

Query: 534  VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDME 593
               P   EVA     +P  K E P  K   +       P K VP     E  PVP+   E
Sbjct: 9295 ---PAPEEVAPVP--IPK-KVEPPAPKVPEV-------PKKPVPE----EKKPVPVPKKE 9337

Query: 594  IAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKP 653
             A                            +P  V    KK   P  E+ +   + ++K 
Sbjct: 9338 PA----------------------------APPKVPEVPKK---PVPEEKIPVPVAKKK- 9365

Query: 654  CNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 713
              + P+++     G+   E+   +   T  + + PP   +P  P+KK             
Sbjct: 9366 -EAPPAKVPEVQKGVVTEEK---ITIVTQREESPPP--AVPEIPKKKVP----------- 9408

Query: 714  TSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPA-----APPKRPAVASARPSILPS 768
              + K  P    + P P  +  L KKP+      VP      APP R  V  ++ +++  
Sbjct: 9409 -EERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEV--SKKTVVEE 9465

Query: 769  KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA--------KTTTAAAVASTG 820
            K    +       P++        SA    S S+  + V+        +     A  +  
Sbjct: 9466 KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEY 9525

Query: 821  PSSRSPSTLLPKKPTAI---KTEGKPAEV-----KKMTAK-SVPADLSRPKSTSTSSMKK 871
                 P   + ++   I   + E +PAEV     KK+  K  +PA +  P         K
Sbjct: 9526 EVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPK 9585

Query: 872  TTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 918
                    PA   VP + K  P        P + ++P    P    P
Sbjct: 9586 KIVPEKKVPAP--VPKKEKVPP--------PKVPEEPKKPVPEKKVP 9622



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 156/718 (21%), Positives = 273/718 (38%), Gaps = 95/718 (13%)

Query: 207   EAVAEPPQPTAVPLELAKEIEMA-----SEERPPAQALEIMMGLKTTDMAPSKETEMALA 261
             E V  PP+  A+P +   E ++A     +++ PP +A E+       +     E +++ A
Sbjct: 9419  EEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRA-EVSKKTVVEEKRFVAEEKLSFA 9477

Query: 262   KDMAL-ATKTEVALAKDM-----ESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVA 315
                 +  T+ EV+  ++      E    + V   ++ +   E+++   + ME P E  V 
Sbjct: 9478  VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537

Query: 316   -----LVKDVRW-PTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKD 369
                  + K V   P E      K +VL  +    PAK        E   P K+  AP K 
Sbjct: 9538  EKLHIISKRVEAEPAEVTERQEKKIVLKPKI---PAK-------IEEPPPAKVPEAPKKI 9587

Query: 370   MGPPKENKK--ETERASPIKMDLAPSKDMG----PPKENKI---VPAKDLVLLSEIEVAQ 420
             +   K      + E+  P K+   P K +     PPK  K+   +PAK  V    +++ Q
Sbjct: 9588  VPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAK--VTERHMQITQ 9645

Query: 421   ANDI-ISSTEISSAEKVALSSETEVALARDMTL---------PP----ETNVILTKDKAL 466
                + ++ T+  +  K  +  E + A+  +  L         PP    E    + K++ +
Sbjct: 9646  EEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705

Query: 467   PLEA---EVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP 523
              +EA   E  P+K++  + E E A   +    +V+     ++       E    +     
Sbjct: 9706  SIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEY 9765

Query: 524   PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 583
              + E    +      E E  +TE + P      P+ ++ V T      PAK +      E
Sbjct: 9766  DQYEEYEEREYERYEEHEEYITEPEKPI--PVKPVPEEPVPTKPK-APPAKVLKKAVPEE 9822

Query: 584   ATPVPIKDM------EIAQTQKGISEDSHLESL-----QDVGQSAAPTFMISPETVTGTG 632
               PVPI         ++ +  K + E+    S+     + V + AA   M  P+ V    
Sbjct: 9823  KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPM-KPKRVVAE- 9880

Query: 633   KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692
             +K  +P +E +   ++ E  P   +P E++ E   +   EE   +V      I    ++E
Sbjct: 9881  EKVPVPRKEVAPPVRVPE-VPKELEPEEVAFEEEVVTHVEEY--LVEEEEEYI----HEE 9933

Query: 693   LPPSPEKKTKPLATTQ----PAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 748
                  E++  P+   +    P K    + K  P    K+  P  +  + KKP       V
Sbjct: 9934  EEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP----EEKV 9989

Query: 749   PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 808
             P   PK+     A+   +P K V  + +      +  A P+K    P      K     A
Sbjct: 9990  PVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049

Query: 809   KTTTAAAVASTGPSSRSPSTLLP--KKPTAI--KTEGKPAEVKKMTAKSVPADLSRPK 862
                  A  A        P  L+P  KKPT +  K E  P +V K   + VP  ++ P+
Sbjct: 10050 PKKVEAPPAKV---PEVPKKLIPEEKKPTPVPKKVEAPPPKVPK-KREPVPVPVALPQ 10103



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 163/810 (20%), Positives = 304/810 (37%), Gaps = 111/810 (13%)

Query: 141 FKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHS 200
           F++  + DL  L+   +   D+  ++       +S G +     ++ QG   E + +  +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVN---ATNSVGRATSTAELLVQG--EEEVPAKKT 204

Query: 201 ESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMAL 260
           ++ VS   ++E  Q       + K+IE   + R  A    ++ G              A 
Sbjct: 205 KTIVSTAQISESRQT-----RIEKKIEAHFDARSIATVEMVIDG--------------AA 245

Query: 261 AKDMALATKTEVALAKDMESPTKLDVT----LAKDMQPSMESDMALVKDMELPTEKEVAL 316
            + +   T   +       SPT   +     LA+   PS             P     + 
Sbjct: 246 GQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPS-------------PIRHSPSP 292

Query: 317 VKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKEN 376
           V+ VR PT + V S       + + +   +   L+++T+ ++     +A   ++ PP + 
Sbjct: 293 VRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQAST-----VATGPEVPPPWKQ 347

Query: 377 KKETERASPIKM---DLAPSKDMGPPKE-NKIVPAKDLVLLSEIEVAQANDIISSTEISS 432
           +     +S  +M    L  S  +   +        ++ V +S    A A+  +S++   +
Sbjct: 348 EGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAAS--VSASASYA 405

Query: 433 AEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPET---EIAPA 489
           AE VA  ++ EV    D +    T V+   D A   E  ++ V+  AQ   T    I PA
Sbjct: 406 AEAVATGAK-EVKQDADKSAAVAT-VVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPA 463

Query: 490 -----KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPE------------TEVVLIK 532
                K+   + V +V +  D +   E +    + +T   E            TE   + 
Sbjct: 464 QEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVP 523

Query: 533 NVCLPP----EMEVALTEDQVPALK--TEAPLAKDGVLTLANNVTPAKDVPPLSETEATP 586
            V +      E E  ++E+     K  T+  + ++  +T A+ V  A      ++ E  P
Sbjct: 524 KVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVA--TAKSTKLETVP 581

Query: 587 VPIKDMEIAQTQKGISEDSHLESLQD--VGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644
              ++    Q Q  +S +  ++  +   V +    T  +  + +   G++      E   
Sbjct: 582 GAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQ 641

Query: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPE---KKT 701
           + +   RK   ++ + LS+     A+ +E   ++       T     ++        KK 
Sbjct: 642 ITQEKMRK--EAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKA 699

Query: 702 KPLATTQPAKTSTS-KAKTQPTSLPKQPAP-TTIGGLNKKPMSLASGLVPAAPPKRPAVA 759
           + +AT   A      +   +P  L +  A  TT+    K+ +S A     A PP+RPA  
Sbjct: 700 EAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAK---VAEPPQRPA-- 754

Query: 760 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 819
            + P ++P K VKP+ I   +AP +  +  K          S+  +T   TT        
Sbjct: 755 -SEPHVVP-KAVKPRVI---QAPSE--THIKTTDQKGMHISSQIKKTTDLTTERLVHVDK 807

Query: 820 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 879
            P + SP   + K        G  A +    A S  A L +  S ++S+ K T ++   A
Sbjct: 808 RPRTASPHFTVSKISVPKTEHGYEASI----AGSAIATLQKELSATSSAQKITKSVK--A 861

Query: 880 PAAGVVPSRVKATPMPSRPSTTPFIDKKPT 909
           P      +RV+A P P      PF D   T
Sbjct: 862 PTVKPSETRVRAEPTPL--PQFPFADTPDT 889



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 50/230 (21%), Positives = 79/230 (34%), Gaps = 26/230 (11%)

Query: 779  AKAPEKRASP-----SKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 833
            AK PEK+A P      KP      ++  +  +   + T    V+           ++P+K
Sbjct: 9167 AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKK---------IVPQK 9217

Query: 834  PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP 893
            P+    + +  EVK     +    +S  K    S  ++  +++       +V        
Sbjct: 9218 PSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVA 9277

Query: 894  MPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 953
            +  R    P + + P    P    P          AP +  V  K    E  K  P    
Sbjct: 9278 ISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK-KPVP---- 9332

Query: 954  AKVEKKTEAAATTRKPE----SNAVTKTAGPIASAQKQPAGKVQIVSKKV 999
              V KK E AA  + PE         K   P+A  ++ P  KV  V K V
Sbjct: 9333 --VPKK-EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 13/113 (11%)

Query: 650  ERKPCNSQPSELSSETSGIAR--PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATT 707
            E KP +   S +   T  I    PEE  PVV+        PP   L P+PE+K  P    
Sbjct: 8931 ELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVA--------PPIPLLLPTPEEKKPPPKRI 8982

Query: 708  QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760
            +  K +  K   +  + PK+  P     + KKP    + L+PA  P+   V+S
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPRE--EIVKKPPP-PTTLIPAKAPEIIDVSS 9032


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 87.8 bits (216), Expect = 5e-17
 Identities = 215/1042 (20%), Positives = 351/1042 (33%), Gaps = 157/1042 (15%)

Query: 58   GNSESKKKPCS-------ETSQIEDTP---SSKPTLLANGGHGVEGSDTTGSPTEFLEEK 107
            GN+   + P S       ETS +  TP   S+  T  +  G     +D T  PT    E 
Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG 2395

Query: 108  MAYQEYPNSQNWP----EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSS----AT 159
                        P    E +     P     P+ T                P+S     T
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455

Query: 160  ADTSIFAGQNDPLKDSYGMSPCNTAV---VPQGWSVEALNSPHS-ESFVSPEAVAEPPQ- 214
               +       P+  S   +   T V    P   S EA +SP + E  V P + A     
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGST 2515

Query: 215  ----------PTAVPLELAKEIEMASEERPPAQALEIMMGLKT---TDMAPSKETEMALA 261
                      P A P              P   + EI     +   T M  S  +E +  
Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575

Query: 262  -KDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDV 320
             + M ++TK   +      S T +D ++         S     KD  +P           
Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIS--------- 2626

Query: 321  RWPTETDVSSAKNVVLPTETEVAPAKDVTLLK-----ETERASPIKMDLAPSKDMGPPKE 375
               T ++VS++   +L +   VA ++  TL        T   +      +P+   G    
Sbjct: 2627 ---TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 376  NKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEK 435
                 ER++P+   L  +          ++   +   LS   V  +  + +S E SS+  
Sbjct: 2684 TSTPGERSTPLTNILVSTT---------LLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734

Query: 436  VALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPS 495
             A  +   ++   D + P  + ++ T   A    + V+       +P T    A   +P+
Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASS-SPT 2793

Query: 496  TVKEVGLLKDMSPLSETEMALGK---DVTPPPETEVVLIKNVCLPPEMEVALTEDQVPAL 552
            T  EV  +   +P SET   L     + TP   +E   +     P +    +T       
Sbjct: 2794 TA-EVTSMPTSTP-SETSTPLTSMPVNHTPVASSEAGTLSTT--PVDTSTPVTTS---TK 2846

Query: 553  KTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQD 612
             + +P   +G++   +  +          T  T +P+    +A ++      + +++   
Sbjct: 2847 ASSSPTTAEGIVVPISTASEGS-------TLLTSIPVSTTPVASSEASTLSTTPVDTSIP 2899

Query: 613  VGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKL---------GERKPCNSQPSELSS 663
            V  S   +   SP T  GT    S P+E  + L  +          E    ++ P +  +
Sbjct: 2900 VTTSTEGSS--SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRT 2957

Query: 664  ETSGIARPEEGRPVVSGTGNDITTPPNKELP-PSPEKKTKPLATTQPAKTSTSKAKTQP- 721
              +  A          GT   I+TP  +  P  S    T P+A+++ +  S + A T   
Sbjct: 2958 PVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017

Query: 722  --TSLPKQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDVKPK-PI 776
              TS     +PTT  G      + + G  P  + P     VA    S L +  V    P+
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077

Query: 777  ADAKAPEKRASPSKPASAPASRSGSKST-------QTVAKTTTAAAVASTGP-------- 821
              +       +P++  S P S     ST        T   T++A +  ST P        
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137

Query: 822  ----SSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLSRPKST 864
                +  SP+T      PT+  +EG                 +  T  + P D S P +T
Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTT 3197

Query: 865  STSSMKKT----TTLSGTAPAAGVVPSR---VKATPMPSRP----STTPFIDKKP--TSA 911
            ST +   T    T++  + P+ G+ P     V  TP+ S      STTP     P  TS 
Sbjct: 3198 STEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST 3257

Query: 912  KPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPES 971
            + SS+ P     +  TS P         GST  +   P         +T   +TT    S
Sbjct: 3258 EASSSPPTAEGTSMPTSTP-------SEGSTP-LTSMPVSTTTVASSETSTLSTTPADTS 3309

Query: 972  NAVT-----KTAGPIASAQKQP 988
              VT      ++ PIA     P
Sbjct: 3310 TPVTTYSQASSSPPIADGTSMP 3331



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 174/806 (21%), Positives = 296/806 (36%), Gaps = 104/806 (12%)

Query: 205  SPEAVAEPP--QPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAK 262
            S EA + PP  + T++P     E        P +  +       T    P+  +      
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076

Query: 263  DMALATKTEVALAKDMESPTKLDVTLAKDMQP--SMESDMALVKDMELPTEKEVALVKDV 320
              A ++ T    A     PT    T ++   P  S+     LV   E  T     +   +
Sbjct: 1077 SQASSSSTT---ADGTSMPTS---TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI 1130

Query: 321  RWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERAS-PIKMDLAPSKDMGP----PKE 375
               T T+ SS+      T    +P  + T    T  AS P+   L  S +       P +
Sbjct: 1131 PVTTSTEASSSPTTAEGTSIPTSPPSEGT----TPLASMPVSTTLVVSSEANTLSTTPVD 1186

Query: 376  NKKE----TERASPIKMDLAPSKDMGPPKENKI----VPAKDL-VLLSEIEVAQANDIIS 426
            +K +    TE +SP       S     P E       +P +   V  SE      + + +
Sbjct: 1187 SKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246

Query: 427  STEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEI 486
            ST ++++ + + S  T    +   +   E + +LT   ++P+   +    + + L  T +
Sbjct: 1247 STPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLT---SIPVSTTLVTSPEASTLLTTPV 1303

Query: 487  ------APAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 540
                    + +V+ S     G     S  SE    L    + P  T +V    + +   +
Sbjct: 1304 DTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPL---TSIPVNTTLVASSAISI---L 1357

Query: 541  EVALTEDQVPAL-KTEA---PLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596
                 ++  P    TEA   P   +G  T   N  P++   PL+    +  P+   E A 
Sbjct: 1358 STTPVDNSTPVTTSTEACSSPTTSEG--TSMPNSNPSEGTTPLTSIPVSTTPVVSSE-AS 1414

Query: 597  TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKL--GERKPC 654
            T      D+          +++PT      T  G     S P+E  + L+ +        
Sbjct: 1415 TLSATPVDTSTPGTTSAEATSSPT------TAEGISIPTSTPSEGKTPLKSIPVSNTPVA 1468

Query: 655  NSQPSELSSETSGIARPEEGRPVVS-------GTGNDITTPPNKELPPSPEKKTKPLATT 707
            NS+ S LS+       P      VS       GT   I+TP       S    + P++TT
Sbjct: 1469 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEG----STALTSIPVSTT 1524

Query: 708  QPAKTSTSKAKTQP--TSLP------KQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPA 757
              A +  +   T P  TS P         +PTT  G + +  + + G  P  + P     
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTML 1584

Query: 758  VASARPSILPSK--DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTT--- 812
            V S+  + L +   D K +  A  +A     +     +      GS    ++  +TT   
Sbjct: 1585 VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVA 1644

Query: 813  ---AAAVASTGPSSRSP--------STLLPKK----PTAIKTEGKPAEVKKMTAKSVPAD 857
               A+ +++T   S SP        S+  P +    PT+  TEG+   +  +T ++ P  
Sbjct: 1645 SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR-TPLTSITVRTTPVA 1703

Query: 858  LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 917
             S   + ST+ +  +T ++ T+  A   P+  + T MP+   +TP     P ++ P STT
Sbjct: 1704 SSAISTLSTTPVDNSTPVT-TSTEARSSPTTSEGTSMPN---STPSEGTTPLTSIPVSTT 1759

Query: 918  PRLSRLATNTSAPDLKNVRSKVGSTE 943
            P LS  A+  SA  +        STE
Sbjct: 1760 PVLSSEASTLSATPIDTSTPVTTSTE 1785



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 165/730 (22%), Positives = 261/730 (35%), Gaps = 101/730 (13%)

Query: 324  TETDVSS----AKNVVLPTETEV---APAKDVTLLKETERASPIKMDLAPSKDMGPPKEN 376
            T T+VSS    A+   +PT T      P   +T+      +S I        D   P   
Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723

Query: 377  KKETERASPIKMD------LAPSKDMGP----PKENKIVPAKDLVLLSEIEVAQANDIIS 426
              E  R+SP   +        PS+   P    P     V + +   LS   +  +  + +
Sbjct: 1724 STEA-RSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782

Query: 427  STEISS----AEKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAEVAPVKD 477
            STE +S    AE  ++ + T       +T  P ++ ++   +A      P+++    V  
Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTS 1842

Query: 478  MAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLP 537
             A       A    +A ST  E        P+S T +A   +      T  V    V   
Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA-SSETNTLSTTPAVTSTPVTTY 1901

Query: 538  PEMEVALTEDQVPALKTEAPLAKDGVLT---LANNVTPAKDVPPLSETEA-TPVPIKDME 593
             ++  + T     ++ T  P      LT   ++     + ++  LS T A T  P+    
Sbjct: 1902 AQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYS 1961

Query: 594  IAQ----TQKGISEDSHLESLQDVGQSAAP---TFMISPE--TVTGTGKKCSLPA----E 640
             A     T  G S  +   S      ++ P   T ++S E  T++ T    S PA    E
Sbjct: 1962 QASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021

Query: 641  EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK 700
              S     G      S PSE ++  +G+  P     VVS  GN ++T P        + K
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGM--PVSTTLVVSSEGNTLSTTP-------VDSK 2072

Query: 701  TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760
            T+   +T+ + ++T++  +   S P + +P     L   P+S      P A         
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPL----LTSIPLSTTPVASPEASTLSTTPVD 2128

Query: 761  ARPSILPSKDVKPKPIA------DAKAPEKRASP--SKPASAPASRSGSKSTQTVAKTTT 812
            +   ++ S +V   PI              R +P  S P S     S + ST +     T
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188

Query: 813  AAAVASTGPSSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLS 859
            +  V ++  +  SP+T      PT+  +EG                 +  T  + P D S
Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS 2248

Query: 860  RPKSTSTSSMKKTTTLSGTA-PAAGVVPSRVKATPMP-----------SRPSTTPFIDKK 907
             P +TST +    TT  GT+ P + +       T +P           S  STTP     
Sbjct: 2249 TPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNT 2308

Query: 908  P--TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAT 965
            P  TS + SS  P     A  TS P      S  G+T  +   P         +T   +T
Sbjct: 2309 PFTTSTEASSPPP----TAEGTSMP---TSTSSEGNTP-LTRMPVSTTMVASFETSTLST 2360

Query: 966  TRKPESNAVT 975
            T    S  VT
Sbjct: 2361 TPADTSTPVT 2370



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 205/996 (20%), Positives = 339/996 (34%), Gaps = 125/996 (12%)

Query: 114  PNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLK 173
            P S   P+ TN          P  T   K+   + +  L  P   +   +I A  +    
Sbjct: 201  PESTTIPKSTNSEGSTPLTSMPAST--MKVASSEAITLLTTPVEISTPVTISAQASSSPT 258

Query: 174  DSYGMSPCNTAVVPQGWSVEALNSPHSESFV-SPEAVAEPPQPTAVPLELAKEIEMASEE 232
             + G S  N+A  P G S      P S   V S EA      P A  + +    E AS  
Sbjct: 259  TAEGPSLSNSA--PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE-ASSS 315

Query: 233  RPPAQALEIMMGLKTTDMAPSKET----------EMALAKDMALATKTEV-------ALA 275
               A+   I     T    P   T          EM+      + T T V       +L 
Sbjct: 316  PTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLP 375

Query: 276  KDMESPTKLDVTLAKDMQP--SMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKN 333
               E+ + L  TL++   P  +M     LV   E  T   + +       T ++ SS+  
Sbjct: 376  TTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435

Query: 334  VVLPTETEVA-PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKE----TERASPIKM 388
                T    + P++  T L     ++        S     P ++K +    TE +S    
Sbjct: 436  TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPT 495

Query: 389  DLAPSKDMGPPKENKIVPAKDL------VLLSEIEVAQANDIISSTEISSAEKVALSSET 442
                S     P E    P   +      V  SE        + +ST ++++ + + SS T
Sbjct: 496  AEVNSMPTSTPSEGS-TPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTT 554

Query: 443  EVALARDMTLPPETNVILTK---DKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKE 499
                +   + P E +  LT       L + +E +          T +  + + + S+   
Sbjct: 555  PEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA 614

Query: 500  VGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLA 559
             G     S  SE     G  +T    +  ++  +         A T    P + +  P+ 
Sbjct: 615  EGTSMPTSTYSER----GTTITSMSVSTTLVASSE--------ASTLSTTP-VDSNTPVT 661

Query: 560  KDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAP 619
                 T ++       +P  + TE +  P+  M +  T    SE S L S   V  S   
Sbjct: 662  TSTEATSSSTTAEGTSMPTSTYTEGS-TPLTSMPVNTTLVASSEASTL-STTPVDTSTPV 719

Query: 620  TFMI----SPETVTGTGKKCSLPAEEDSVLEKLGERKPC--NSQPSELSSE--------- 664
            T       SP T  G     S P+E  + L  +   K    +S+ S LS+          
Sbjct: 720  TTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHIT 779

Query: 665  -----------TSG----IARPEEGRPVVSGTG---NDITTPPNKELPPSPEKKTKPLAT 706
                       T G    I+ P EG P+++        +T+P    L  +P     P+ T
Sbjct: 780  TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTT 839

Query: 707  TQPAKTSTSKAK--TQPTS--------LPKQPAPTT------IGGLNKKPMSLASGLVPA 750
            +    +S + A+  + PTS        L   P  TT      I  L+  P+  ++ +  +
Sbjct: 840  STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNS 899

Query: 751  APPKRPAVAS---ARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKSTQT 806
               +     S   + P+  P +   P   + D+  P   +     ++ P   S   +T T
Sbjct: 900  TEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST 959

Query: 807  VAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTST 866
             A ++   A  ++ P+S       P   T + +    A  +  T  + P D + P +TST
Sbjct: 960  EATSSPTTAEGTSIPTSTPSEGTTPLTSTPV-SHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 867  SSMKKTTTLSGTA-----PAAGVVP-------SRVKATPMPSRPSTTPFIDKKPTS---- 910
             +     T  GT+     P+ G  P       + + A+   S  STTP     P +    
Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078

Query: 911  AKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE 970
            A  SSTT   + + T+T +     + S   ST  +        +     T    TT    
Sbjct: 1079 ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA 1138

Query: 971  SNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQS 1006
            S++ T   G          G   + S  VS + + S
Sbjct: 1139 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174



 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 188/931 (20%), Positives = 307/931 (32%), Gaps = 163/931 (17%)

Query: 156 SSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHS-ESFVSPEAVAEPPQ 214
           SS T+DT        P   S  M+P  +    +  S      P S E   SP        
Sbjct: 96  SSVTSDT--------PGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDV 147

Query: 215 PTAVPLELAKEIEMASEERPPAQALEIMMGLK-TTDMAPSKETEMALAKDMALATKTEVA 273
           P + P E +    MA     P  + E    L    DM+    T    +        T + 
Sbjct: 148 PMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIP 207

Query: 274 LAKDMESPTKLDVTLAKDMQ-PSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAK 332
            + + E  T L    A  M+  S E+   L   +E+ T   ++       PT  +  S  
Sbjct: 208 KSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSS-PTTAEGPSLS 266

Query: 333 NVV----------LPTETEVAPAKDVTLLKETERASPIKM------DLAPSKDMGPPKEN 376
           N            +P    +  + + + L  T  A+ I +        +P+   G     
Sbjct: 267 NSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPT 326

Query: 377 KKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISS---- 432
              TE ++P+            P     V   ++  LS   V  +  + +STE SS    
Sbjct: 327 STYTEGSTPLT---------STPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTT 377

Query: 433 AEKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAE--VAPVKDMAQLP--- 482
           AE  ++ + T    +  +T  P + +++   +A     +P++++  V    + +  P   
Sbjct: 378 AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA 437

Query: 483 -ETEIA---PAKDVAPSTV----------KEVGLLKDMSPLSETEMALGKDVTPPPETEV 528
            +T IA   P++   P T            E   L      S+T++    + +  P T  
Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE 497

Query: 529 VLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP-- 586
           V       P E    LT   V  +   +  A     T  +  TP       S +  TP  
Sbjct: 498 VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEG 557

Query: 587 ------------VPIKDMEI-----------------AQTQKGISEDSHLESLQDVGQSA 617
                        P+ +M +                 A +   ++  S   S     +  
Sbjct: 558 TSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGT 617

Query: 618 A-PTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRP 676
           + PT   S    T T    S      S    L      ++ P   S+E +  +   EG  
Sbjct: 618 SMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTS 677

Query: 677 VVSGTGNDITTP-----PNKELPPSPEKKT---KPLATTQPAKTSTSKAKT--------Q 720
           + + T  + +TP      N  L  S E  T    P+ T+ P  TST  + +         
Sbjct: 678 MPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASM 737

Query: 721 PTSLPKQPA-PTTIGGLNKKPMSLASGLVPAAPPKRPAV-------ASARPS-------- 764
           PTS P + + P T   ++K  ++ +     +  P   +        AS  P+        
Sbjct: 738 PTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP 797

Query: 765 ---------ILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA 815
                    +L S  V   P+   +A     +P    S   + +   S+ T A+ T+   
Sbjct: 798 ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT 857

Query: 816 VASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 875
             ST    R+P T +P   T + T          T  + P D S P + ST +    TT 
Sbjct: 858 --STYSEGRTPLTSMPVSTTLVATSAIS------TLSTTPVDTSTPVTNSTEARSSPTTS 909

Query: 876 SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNV 935
            GT                 S P++TP     P ++ P STTP +S  A   SA  +   
Sbjct: 910 EGT-----------------SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTS 952

Query: 936 RSKVGSTENIKHQPGGGRAKVEKKTEAAATT 966
                STE            +   T +  TT
Sbjct: 953 TPVTTSTEATSSPTTAEGTSIPTSTPSEGTT 983



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 169/793 (21%), Positives = 279/793 (35%), Gaps = 95/793 (11%)

Query: 204  VSPEA--VAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALA 261
            VS EA  ++  P  T+ P   + E   A+     A+ + I     +    P K   ++  
Sbjct: 1409 VSSEASTLSATPVDTSTPGTTSAE---ATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNT 1465

Query: 262  KDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR 321
                    T      D  SP      ++    P+  + +A+      P+E   AL   + 
Sbjct: 1466 PVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI----STPSEGSTALTS-IP 1520

Query: 322  WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETE 381
              T T  SS  N +  T     PA   T +    +AS      +P+   G   +    +E
Sbjct: 1521 VSTTTVASSEINSLSTT-----PAVTSTPVTTYSQASS-----SPTTADGTSMQTSTYSE 1570

Query: 382  RASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSE 441
             ++P+            P    +V + +   LS   +     + +STE SS+     SS 
Sbjct: 1571 GSTPLT---------SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSM 1621

Query: 442  TEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVG 501
            T       ++ P E + +LT   ++P+        + + L  T +     V  ST  EV 
Sbjct: 1622 T-------ISTPSEGSPLLT---SIPVSTTPVASPEASTLSTTPVDSNSPVITST--EVS 1669

Query: 502  LLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPA-------LKT 554
                 SP      ++         T +  I     P       T    P          T
Sbjct: 1670 ----SSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTST 1725

Query: 555  EA---PLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQ 611
            EA   P   +G  T   N TP++   PL+    +  P+   E A T      D+      
Sbjct: 1726 EARSSPTTSEG--TSMPNSTPSEGTTPLTSIPVSTTPVLSSE-ASTLSATPIDTSTPVTT 1782

Query: 612  DVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARP 671
                +++PT        T T  +   P     V   L      NS+ S LS+       P
Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTL----VANSEASTLSTTPVDSNSP 1838

Query: 672  EEGRPVVSGT-----GNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP--TSL 724
                  VS +     G  I T    E   S    + P++TT  A + T+   T P  TS 
Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATSTPSE--GSTALTSIPVSTTTVASSETNTLSTTPAVTST 1896

Query: 725  PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 784
            P     TT   ++  P +     +P + P+       RP  L S  V    +A ++    
Sbjct: 1897 PV----TTYAQVSSSPTTADGSSMPTSTPRE-----GRPP-LTSIPVSTTTVASSEINTL 1946

Query: 785  RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 844
              + +   +   + S + S+ T A  T+    A +  S+  P T +P   T + +     
Sbjct: 1947 STTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGST--PLTSMPLSTTLVVSS---- 2000

Query: 845  EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI 904
              +  T  + P D S P +TST      TT  GT+      PS  + TP+   P +T  +
Sbjct: 2001 --EASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS-TPSE-RTTPLAGMPVSTTLV 2056

Query: 905  DKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAA 964
                +     STTP  S+    T++ +  +  +  GS+  I   P  G   +     +  
Sbjct: 2057 --VSSEGNTLSTTPVDSKTQV-TNSTEASSSATAEGSSMTIS-APSEGSPLLTSIPLSTT 2112

Query: 965  TTRKPESNAVTKT 977
                PE++ ++ T
Sbjct: 2113 PVASPEASTLSTT 2125



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 186/822 (22%), Positives = 285/822 (34%), Gaps = 134/822 (16%)

Query: 205  SPEAVAEPP--QPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAK 262
            S EA + PP  + T++P   + E        P +  +       T    P+  +      
Sbjct: 2313 STEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372

Query: 263  DMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRW 322
              A ++ T    A D   PT      +  +     S M +V   E  T     +      
Sbjct: 2373 SQAGSSPTT---ADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS-EASTHSTTPVDTSTPV 2428

Query: 323  PTETDVSSAKNVVLPTETEVAPAKDVTLLKETERAS-PIKMDLAPSKDMGPPKENKKETE 381
             T T+ SS+      T    +P  + T    T  AS P+      S + G       +T 
Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGT----TPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484

Query: 382  RASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSE 441
                   + + S       E+ +VP   +   SE      +  +S+T ++S E   LS  
Sbjct: 2485 TPMTTSTEASSSPTTA---EDIVVP---ISTASEGSTLLTSIPVSTTPVASPEASTLS-- 2536

Query: 442  TEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVG 501
                     T P ++N  +     +   A  A    M     +E +      P + K + 
Sbjct: 2537 ---------TTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587

Query: 502  LLKDMSPLSETEMALGKDVTPPPETEV--VLIKNVCLP----PEMEVALTE---DQVPAL 552
               + S LS T +     VT   ET       K+  +P     E+  +LT      +P  
Sbjct: 2588 S-SEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646

Query: 553  KTEAPLAKDGVL---TLANNVTPAKDVPPLSETEATPV--------PIKDMEIAQTQKGI 601
             +EA       +   TL    T     P  +E  + P         P+ ++ ++ T    
Sbjct: 2647 SSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN 2706

Query: 602  SEDSHLESLQDVGQSAAPTFMI----SPETVTGTGKKCSLPAEEDSVLEKL--------- 648
            SE S L S   V  S   T       SP T  GT  + S P++  + L  +         
Sbjct: 2707 SEASTL-STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVAS 2765

Query: 649  ------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK 702
                         S P   S+E S      E   + + T ++ +TP    L   P   T 
Sbjct: 2766 SEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTP----LTSMPVNHT- 2820

Query: 703  PLATTQPAKTSTSKAKTQP---TSLPKQPAPTTIGGLNKKPMSLASG---LVPAAPPKRP 756
            P+A+++    ST+   T     TS     +PTT  G+   P+S AS    L+ + P    
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGI-VVPISTASEGSTLLTSIPVSTT 2879

Query: 757  AVASARPSILPSKDVKPK-PIADA----KAPEKRASPSKPASAPA--------------- 796
             VAS+  S L +  V    P+  +     +P      S P S P+               
Sbjct: 2880 PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP 2939

Query: 797  ---SRSGSKSTQTVAKTT--TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM-- 849
               S + + ST  V   T  T +A AS+ P++   +++    P   +T      V  M  
Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV 2999

Query: 850  ------TAKSVPADLSRPKSTSTSSMKKTTTLSGT-----APAAGVVP-------SRVKA 891
                  T    PAD S P +TST +    TT  GT      P+ G  P       +   A
Sbjct: 3000 ASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059

Query: 892  TPMPSRPSTTPFIDKKP--TSAKPSST-TPRLSRLATNTSAP 930
             P  S  STTP     P  TS + SS+ TP     A  TS P
Sbjct: 3060 IPEASTLSTTPVDSNSPVVTSTEVSSSPTP-----AEGTSMP 3096



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 160/804 (19%), Positives = 273/804 (33%), Gaps = 109/804 (13%)

Query: 200  SESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTT--DMAPSKETE 257
            +E+ +SP        PT+ P E    +        P  + E+   L TT  D      T 
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT-LSTTPVDSNTLVTTS 3433

Query: 258  MALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALV 317
               +    +A  T +  +   E  T L + +     P   S+ + +    + T   V   
Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSI-MPLSTTPVASSEASTLSTTPVDTSTPVTTS 3492

Query: 318  KDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENK 377
                 PT +  ++A+   +PT T    +  +T +  +   +P+    A +    P   N 
Sbjct: 3493 S----PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS--TTPVASSEASTLSTTPVDSNT 3546

Query: 378  KETERA----SPIKMDLAPSKDMGPPKENK-----------IVPAKDLVLLSEIEVAQAN 422
              T  +    SP  + +   + M  P E              V + +    S   V ++ 
Sbjct: 3547 FVTSSSQASSSPATLQVTTMR-MSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRST 3605

Query: 423  DIISSTEISSA----EKVALSSETEVALARDMTLPPETNVILTKDKA-----LPLEAEVA 473
             + +ST+ +S     E + L   T   ++  +T+ P +   +T  +A     LP++    
Sbjct: 3606 PVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTST- 3664

Query: 474  PVKDMAQLPETEIAPAKDVAPS-TVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK 532
            PV    Q+  + + P     P  T  E        P+S T +   +  T    + V    
Sbjct: 3665 PVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTP 3724

Query: 533  NVCLPPEMEVALTEDQVPALKTEAPLAKDGV-LTLANNVTPAKDVPPLSETEATPVPIKD 591
                   +  + T D    +    P+    +  T+  + TP    P  S T + P     
Sbjct: 3725 VTTSTEAISSSATLDST-TMSVSMPMEISTLGTTILVSTTPVTRFPE-SSTPSIPSVYTS 3782

Query: 592  MEIAQTQKGISEDSHLESLQDVGQSAAP-------TFMISPETVTGTGKKCSLPAEEDSV 644
            M +    +G S  + LE    +  S          T +ISP +V         P+E  ++
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMS-------PSEASTL 3835

Query: 645  LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP- 703
                G+     S P   S++    + P E   +     ++ +TP    L  +    + P 
Sbjct: 3836 STPPGD----TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPG 3891

Query: 704  --LATTQPAKTSTS-KAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 760
              +A+T P  TST+    T   S P  P  TTI           S +   + P       
Sbjct: 3892 ASIASTPPLDTSTTFTPSTDTASTPTIPVATTIS---------VSVITEGSTPGTTIFIP 3942

Query: 761  ARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 820
            + P    + DV P                       + +G+ ST  +  T       S+ 
Sbjct: 3943 STPVTSSTADVFP-----------------------ATTGAVSTPVITSTELNTPSTSSS 3979

Query: 821  PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT--LSGT 878
             ++ S ST       A+ T      V   TA S P   SR  +TS S++  T+T   S +
Sbjct: 3980 STTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039

Query: 879  APAAGVVPSRVKATPM------------PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATN 926
                 V PS   + P             P+  ST P      T+  P + T   +R   +
Sbjct: 4040 VTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPS 4099

Query: 927  TSAPDLKNV-RSKVGSTENIKHQP 949
            T       V  + V +   IK  P
Sbjct: 4100 TRTTSFPTVTTTAVPTNTTIKSNP 4123



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 91/406 (22%), Positives = 158/406 (38%), Gaps = 44/406 (10%)

Query: 572  PAKDVPPLSETEATPVPIKDMEIAQ-TQKGISEDSHLESLQDVGQSAAPTFMISPETVTG 630
            P++  P L+    +  P+   E +  +   +  +S + +  +V  S  PT   S +T T 
Sbjct: 2097 PSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTY 2156

Query: 631  TGKKC---SLPAEE----DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
            + ++    S+P        S +  L       S P   S+E        EG  + + T +
Sbjct: 2157 SDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPS 2216

Query: 684  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP---TSLPKQPAPTTIGGLNKKP 740
            + +TP    +P S    T P+ T++ +  S +   T     TS     +PTT  G +   
Sbjct: 2217 EGSTPFTS-MPVS----TMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 2271

Query: 741  MSLASGLVP--AAPPKRPAVASARPSILPSKDV-------------KPKPIADAKA-PEK 784
             +L+ G  P  + P     VA++  S L +  V              P P A+  + P  
Sbjct: 2272 STLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTS 2331

Query: 785  RASPSK------PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAI 837
             +S         P S     S   ST +     T+  V +   +  SP+T      PT+ 
Sbjct: 2332 TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391

Query: 838  KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897
             +EG    +  +   ++P   S   + ST+ +  +T ++ T+  A   P+  + T +P+ 
Sbjct: 2392 YSEGS-TPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVT-TSTEASSSPTTAEGTSIPTS 2449

Query: 898  PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943
            P   P     P ++ P STTP +S  A   S   +        STE
Sbjct: 2450 P---PSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE 2492



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 144/780 (18%), Positives = 262/780 (33%), Gaps = 84/780 (10%)

Query: 135  PIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEA 194
            P+ T P      + L+     S+    TS  A  +  + +   +    T+      S+  
Sbjct: 3405 PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMP 3464

Query: 195  LNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSK 254
            L++       +P A +E    +  P++ +  +  +S         E+      T M  S 
Sbjct: 3465 LST-------TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV------TSMPTST 3511

Query: 255  ETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEV 314
              E +        + T VA ++     T             ++S+  +    +  +    
Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTT-----------PVDSNTFVTSSSQASSSPAT 3560

Query: 315  ALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVT-LLKETERASPIKMDLAPSKDMGPP 373
              V  +R  T ++ SS+   +L + T V  ++  T      +R++P+      +    PP
Sbjct: 3561 LQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620

Query: 374  KENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSA 433
            +         S +   L        P     V   +    S + V  +  +I+ST++SS+
Sbjct: 3621 EVITLPMSTPSEVSTPLTIM-----PVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS 3675

Query: 434  ----EKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPA 489
                E   +   T    +  +T  P +   +T  +   L    + V        TE   +
Sbjct: 3676 PVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTP-SVVTSTPVTTSTEAISS 3734

Query: 490  KDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQV 549
                 ST   V +  ++S L  T +     VT  PE+    I +V     M  A      
Sbjct: 3735 SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS 3794

Query: 550  PAL---KTEAPLA---KDGVLTLANNVTPAKDVPPLSETEATPVPIKDME---IAQTQKG 600
            P      T  P++   +   L     ++P   + P SE      P  D     +  T+ G
Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSP-SEASTLSTPPGDTSTPLLTSTKAG 3853

Query: 601  ---ISEDSHLESLQDVGQSAAP--TFMIS---PETVTGTGKKCSLPAEEDSVLEKLGERK 652
               I  +     +    + + P  T ++S   P +  G     + P +  +      +  
Sbjct: 3854 SFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTA 3913

Query: 653  PCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKT 712
               + P   +   S I         +      +T+      P +    + P+ T+    T
Sbjct: 3914 STPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNT 3973

Query: 713  STSKAKTQPTSLPKQ-----PAPTTIGGLNKKPMSLASGLVPAAP---------PKRPAV 758
             ++ + +  TS         PA TT   L    MS A    P+ P               
Sbjct: 3974 PSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTA----PSTPRTTSRGCTTSASTLS 4029

Query: 759  ASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVA 817
            A++ P    S   +P  P +++  P    S + P + P + S +  T + + TT      
Sbjct: 4030 ATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAV 4089

Query: 818  STGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSG 877
            +T  +   PST     PT   T    A     T KS P        TST ++ +TTT  G
Sbjct: 4090 TTMTTRTKPSTRTTSFPTVTTT----AVPTNTTIKSNP--------TSTPTVPRTTTCFG 4137


>gi|38261962 activating transcription factor 7 interacting protein
            [Homo sapiens]
          Length = 1270

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 171/762 (22%), Positives = 274/762 (35%), Gaps = 91/762 (11%)

Query: 285  DVTLAKDMQPSMESDMA--LVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEV 342
            D T+  D  P  E  +   ++ ++ L  +   + ++  +     D +SA  V    E  +
Sbjct: 356  DTTICSDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVI 415

Query: 343  APAKDVTLLK-----ETERASPIKMDLAPSKD---------------MGPPKENKKETER 382
               K   +L+     ET+   PI   LAPS+D                 P  E K E+  
Sbjct: 416  EDNKSENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSF 475

Query: 383  ASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSE---IEVAQANDIISSTEISSAEKVALS 439
             SP K + + S     PKE  +V + +  +  E    EV   N+  S  E+ S EK    
Sbjct: 476  GSPSKQESSESL----PKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKP 531

Query: 440  SETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPE-------TEIAPAKDV 492
             E E  +  D   P E N    + ++   + +    K    + E        +I    D+
Sbjct: 532  EEEEQVIHEDDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDI 591

Query: 493  APSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQ--VP 550
                 K +  L +   L   + A+        +T V  I+        +  LTE Q  + 
Sbjct: 592  NQKLQKVIQWLLE-EKLCALQCAVFDKTLAELKTRVEKIE---CNKRHKTVLTELQAKIA 647

Query: 551  ALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESL 610
             L      AK+  L   +   P    PP+S  +       +  ++    G      LES 
Sbjct: 648  RLTKRFEAAKED-LKKRHEHPPN---PPVSPGKTVNDVNSNNNMSYRNAGTVRQM-LESK 702

Query: 611  QDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIAR 670
            ++V +SA P+F     TV+ T    + PA   S      + K      S   + TS +  
Sbjct: 703  RNVSESAPPSFQTPVNTVSSTNL-VTPPAVVSS------QPKLQTPVTSGSLTATSVLPA 755

Query: 671  PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--- 727
            P     V +         P   L P P     P+A +   +   S   T  T+ P     
Sbjct: 756  PNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVE 815

Query: 728  ----PAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783
                 +P T+ GL K P+SL S   P  P   P+V S  PSI  +      P+    A +
Sbjct: 816  FISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPS--PSIQRNPTASAAPLGTTLAVQ 873

Query: 784  KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGP-SSRSPSTLLPKKPTAIKTEGK 842
              A P+  +   A+R+   S  TV  +   +   + GP   + P +       A +    
Sbjct: 874  --AVPTAHSIVQATRT---SLPTVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNT 928

Query: 843  PAEVKKMTAKSVPADLSRPKSTSTSSMKKTT----------TLSGTAPAAGVVPSRVKAT 892
               ++  T K++ A +S+  + STS   K T          T+      A   P ++  T
Sbjct: 929  TPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHT 988

Query: 893  PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVR--SKVGSTENIKHQPG 950
            P+ +  S+ P    +P   +P    P L      TS P    +       +T N+ H+P 
Sbjct: 989  PVSTMSSSQPV--SRP--LQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRP- 1043

Query: 951  GGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKV 992
                 V + T      R P ++ V  T  P   AQ    G V
Sbjct: 1044 -----VTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV 1080



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 114/607 (18%), Positives = 193/607 (31%), Gaps = 105/607 (17%)

Query: 374  KENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDL-----VLLSEIEVAQANDIISST 428
            KE+ K+     P    ++P K +     N  +  ++      +L S+  V+++      T
Sbjct: 657  KEDLKKRHEHPP-NPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQT 715

Query: 429  EISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAP 488
             +++     L +   V  ++     P T+  LT    LP     A V    Q+P     P
Sbjct: 716  PVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAP-NTATVVATTQVPSGNPQP 774

Query: 489  AKDVAPSTV----------------KEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK 532
               + P  V                   G L    P    E      V  PP T   L K
Sbjct: 775  TISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFI---SVQSPP-TVSGLTK 830

Query: 533  NVCLPPEMEVALTEDQVPALKTEA----PLAKDGVL--TLANNVTP-AKDVPPLSETEAT 585
            N    P +      + VP++ + +    P A    L  TLA    P A  +   + T   
Sbjct: 831  NPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLP 890

Query: 586  PVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVL 645
             V    +    T +G  +     S      +A      +P     T K       + +  
Sbjct: 891  TVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAAD 950

Query: 646  EKLGERKPCNSQPS-----ELSSETSGIARPEEG---RPVVSGTGNDITTPPNKELPPSP 697
                  K   S  S      +  E SG ++  +     PV + + +   + P + + P+P
Sbjct: 951  STSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAP 1010

Query: 698  EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL-VPAAPPKRP 756
              +   + T+ P++T+     T         APTT+   ++    + + L VP AP    
Sbjct: 1011 PLQPSGVPTSGPSQTTIHLLPT---------APTTVNVTHRPVTQVTTRLPVPRAPANHQ 1061

Query: 757  AVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAV 816
             V +  P+              A+AP +      PA    +   S + + V +TTT    
Sbjct: 1062 VVYTTLPA------------PPAQAPLRGTVMQAPAVRQVNPQNSVTVR-VPQTTTYVVN 1108

Query: 817  ASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL- 875
                  S  P   +  +P  + TE  P  V        P     P   +++S+ +   L 
Sbjct: 1109 NGLTLGSTGPQLTVHHRPPQVHTE-PPRPVHPAPLPEAPQPQRLPPEAASTSLPQKPHLK 1167

Query: 876  --------------------------------------SGTAPAAGVVPSRVKATPMPSR 897
                                                  S T P+       VKA P+P  
Sbjct: 1168 LARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVPSQWKKIGEVKALPLPMA 1227

Query: 898  PSTTPFI 904
             + T F+
Sbjct: 1228 CTLTQFV 1234


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 145/624 (23%), Positives = 230/624 (36%), Gaps = 72/624 (11%)

Query: 192  VEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEI-EMASEERPPAQALEIMMGLKTTDM 250
            ++ +     E+ +  E   E      V  E  KE  E   +E    +  E   G + T  
Sbjct: 444  IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKS 503

Query: 251  APSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310
             P++E      K+     K E     + +SP K +     +++   ++     ++ + P 
Sbjct: 504  PPAEEAASP-EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562

Query: 311  EKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERA-SPIKMDL-APSK 368
            E +    ++ + P E  V S +    P + E   AK     K  E+A SP+K +  +P++
Sbjct: 563  EAKSPEKEEAKSPAE--VKSPEKAKSPAKEE---AKSPAEAKSPEKAKSPVKEEAKSPAE 617

Query: 369  DMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISS- 427
               P KE  K     SP ++  +P K   P KE    P K      E E A++ +   S 
Sbjct: 618  AKSPVKEEAK-----SPAEVK-SPEKAKSPTKEEAKSPEK--AKSPEKEEAKSPEKAKSP 669

Query: 428  --TEISSAEKV-------ALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDM 478
               E  S EK        A S E   +  ++    PE      K++A   E   +PVK+ 
Sbjct: 670  VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729

Query: 479  AQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPP 538
            A+ PE   +P K+ A S  K        SP     + +       P  E         P 
Sbjct: 730  AKTPEKAKSPVKEEAKSPEKA------KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783

Query: 539  EMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQ 598
            + +  + E+     K ++PL +D          P K++P   E ++   P+K+ E  Q  
Sbjct: 784  KAKSPVKEEVKSPEKAKSPLKEDAK-------APEKEIPKKEEVKS---PVKEEEKPQEV 833

Query: 599  KGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERK-PCNSQ 657
            K        E      +  AP    +P+T      K     ++++   K+ E+K P   +
Sbjct: 834  KVKEPPKKAE------EEKAPA---TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884

Query: 658  PSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK--TKPLATTQPAKTSTS 715
            P E   E    A+ EE               P KE P   E K   KP   T+ AK    
Sbjct: 885  PKESKVE----AKKEEAEDKKK------VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934

Query: 716  KAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKP 775
             AK +    P +PA        KK         P   PK  A A      L  +  KPK 
Sbjct: 935  DAKAKE---PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK- 990

Query: 776  IADAKAPEKRASPSKPASAPASRS 799
               A+  EK +S  +  S P  ++
Sbjct: 991  ---AEKAEKSSSTDQKDSKPPEKA 1011



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 129/574 (22%), Positives = 213/574 (37%), Gaps = 85/574 (14%)

Query: 294  PSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKE 353
            P  E+   + ++ + P E +    ++ + P E  V S +    P + E     +    ++
Sbjct: 512  PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE--VKSPEKAKSPAKEEAKSPPEAKSPEK 569

Query: 354  TERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLL 413
             E  SP ++  +P K   P KE  K    A       +P K   P KE    PA      
Sbjct: 570  EEAKSPAEVK-SPEKAKSPAKEEAKSPAEAK------SPEKAKSPVKEEAKSPA------ 616

Query: 414  SEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKAL-PLEAEV 472
             E +     +  S  E+ S EK A S   E A + +    PE     + +KA  P++AE 
Sbjct: 617  -EAKSPVKEEAKSPAEVKSPEK-AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674

Query: 473  -------APVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPE 525
                   +PVK  A+ PE   +P K+ A S  K    +K+ +   E   +  K+    PE
Sbjct: 675  KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734

Query: 526  TEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDV---PPLSET 582
                 +K     PE   A + ++   L  ++P AK          TPAK+    P     
Sbjct: 735  KAKSPVKEEAKSPEK--AKSPEKAKTLDVKSPEAK----------TPAKEEARSPADKFP 782

Query: 583  EATPVPIKDMEIAQTQKG---ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPA 639
            E    P+K+ E+   +K    + ED+                  +PE      ++   P 
Sbjct: 783  EKAKSPVKE-EVKSPEKAKSPLKEDAK-----------------APEKEIPKKEEVKSPV 824

Query: 640  EEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP-PSPE 698
            +E+   +++  ++P      E +  T      ++ +   +         P KE P P  E
Sbjct: 825  KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA---------PKKEAPKPKVE 875

Query: 699  KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV 758
            +K +P A  +P ++     K +     K P P       K+  +       A P ++  V
Sbjct: 876  EKKEP-AVEKPKESKVEAKKEEAEDKKKVPTP------EKEAPAKVEVKEDAKPKEKTEV 928

Query: 759  ASARPSIL----PSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK-STQTVAKTTTA 813
            A   P       PSK  + K  A  K   K     KP   P + + +K   +T++K  + 
Sbjct: 929  AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK 988

Query: 814  AAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847
                    SS +       KP    TE K A+ K
Sbjct: 989  PKAEKAEKSSSTDQK--DSKPPEKATEDKAAKGK 1020



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 126/567 (22%), Positives = 195/567 (34%), Gaps = 93/567 (16%)

Query: 339  ETEVAPAKDVTLLKETERASPIKMDL-APSKDMGPPKENKKETERASPIKMDLAPSKDMG 397
            ET+  PA++     E E  SP+K +  +P++   P KE  K     SP ++  +P K   
Sbjct: 500  ETKSPPAEEAAS-PEKEAKSPVKEEAKSPAEAKSPEKEEAK-----SPAEVK-SPEKAKS 552

Query: 398  PPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN 457
            P KE    P        E +  +  +  S  E+ S EK    ++ E     +   P +  
Sbjct: 553  PAKEEAKSPP-------EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 458  VILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALG 517
              + ++   P EA+ +PVK+ A+ P    +P K  +P+  +     K  SP  E E    
Sbjct: 606  SPVKEEAKSPAEAK-SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE-EAKSP 663

Query: 518  KDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNV-TPAKDV 576
            +    P + E    +    P + E    E     +K EA   +     +     +P K  
Sbjct: 664  EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723

Query: 577  PPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCS 636
             P+ E   TP   K          + E++         + A    + SPE  T       
Sbjct: 724  SPVKEEAKTPEKAKSP--------VKEEAKSPEKAKSPEKAKTLDVKSPEAKT------- 768

Query: 637  LPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPS 696
             PA+E++       R P +  P +  S                         P KE   S
Sbjct: 769  -PAKEEA-------RSPADKFPEKAKS-------------------------PVKEEVKS 795

Query: 697  PEKKTKPLATTQPA-------------------KTSTSKAKTQPTSLPKQPAPTTIGGLN 737
            PEK   PL     A                   K    K K  P    ++ AP T     
Sbjct: 796  PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855

Query: 738  KKPMSLASGLVPAAP------PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
            KK           AP       K PAV   + S + +K  + +       PEK A P+K 
Sbjct: 856  KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA-PAKV 914

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851
                 ++   K+     +   A A   + P+ +  +    KK T  +   KP E  K  A
Sbjct: 915  EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA-PEKKDTKEEKAKKPEEKPKTEA 973

Query: 852  KSVPADLSRPKSTSTSSMKKTTTLSGT 878
            K+   D +  K  S    +K    S T
Sbjct: 974  KAKEDDKTLSKEPSKPKAEKAEKSSST 1000



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 101/474 (21%), Positives = 171/474 (36%), Gaps = 53/474 (11%)

Query: 640  EEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEK 699
            EE  V E++ E +   ++  E   E  G     EG       G + T  P  E   SPEK
Sbjct: 462  EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG-------GEEETKSPPAEEAASPEK 514

Query: 700  KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVA 759
            + K  +  +    S ++AK+      K PA        K P    S       P +    
Sbjct: 515  EAK--SPVKEEAKSPAEAKSPEKEEAKSPAEV------KSPEKAKS-------PAKEEAK 559

Query: 760  SARPSILPSKDVKPKPIADAKAPEKRASPSKP-ASAPASRSGSKSTQTVAKTTTAAAVAS 818
            S   +  P K+    P A+ K+PEK  SP+K  A +PA     +  ++  K       A 
Sbjct: 560  SPPEAKSPEKEEAKSP-AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE-----AK 613

Query: 819  TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 878
            +   ++SP     K P  +K+  K     K  AKS     S  K  + S  K  + +   
Sbjct: 614  SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 879  APAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 938
            A +     S VKA       + +P  ++  +  K  S     ++      +P  +  ++ 
Sbjct: 674  AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733

Query: 939  VGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKK 998
              +   +K +          +       + PE+        P     + PA K    +K 
Sbjct: 734  EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------PAKEEARSPADKFPEKAKS 787

Query: 999  VSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKI-E 1057
                 ++S   +K  +K          ++ K    ++  K   K+ +K +    +VK+ E
Sbjct: 788  PVKEEVKSPEKAKSPLK----------EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837

Query: 1058 SQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISE 1111
              K   +EKA A   + +         + K E    EAP  P     +EPA+ +
Sbjct: 838  PPKKAEEEKAPATPKTEEK------KDSKKEEAPKKEAPK-PKVEEKKEPAVEK 884



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 81/331 (24%), Positives = 133/331 (40%), Gaps = 41/331 (12%)

Query: 191 SVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDM 250
           S E   SP  E   SPE    P +  A   E AK    A  + P      +    K+ + 
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693

Query: 251 APSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPT 310
           A S   E A + + A             +SP K +    +  +  ++ +    +  + P 
Sbjct: 694 AKSPVKEEAKSPEKA-------------KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740

Query: 311 EKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDM 370
           ++E    +  + P       AK + + +     PAK+       E  SP   D  P K  
Sbjct: 741 KEEAKSPEKAKSP-----EKAKTLDVKSPEAKTPAKE-------EARSP--ADKFPEKAK 786

Query: 371 GPPKENKKETERA-SPIKMDL-APSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISST 428
            P KE  K  E+A SP+K D  AP K++ P KE    P K+     E++V +        
Sbjct: 787 SPVKEEVKSPEKAKSPLKEDAKAPEKEI-PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845

Query: 429 EISSAEKV--ALSSETEVALARDMTLPPETNVILTKDKAL--PLEAEVAPVKDMAQLPET 484
           +  +  K      S+ E A  ++    P+  V   K+ A+  P E++V   K+ A+  + 
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKE---APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902

Query: 485 EIAPAKDVAPSTVKEVGLLKDMSPLSETEMA 515
              P K+ AP+ V+   + +D  P  +TE+A
Sbjct: 903 VPTPEKE-APAKVE---VKEDAKPKEKTEVA 929


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 80.5 bits (197), Expect = 9e-15
 Identities = 186/873 (21%), Positives = 289/873 (33%), Gaps = 150/873 (17%)

Query: 235  PAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQP 294
            PA      +   + D  PS  + +  +   +L   T  +L     SPT    +L     P
Sbjct: 368  PATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL-----SPT---TSLILKSSP 419

Query: 295  SMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKET 354
            +      LV  M + +     LV          +++A        T V+P      +   
Sbjct: 420  NATYHYPLVAQMPVSSVGTTPLVVT----NPCTIAAAPTTTFEVATCVSPPMSSGPISNI 475

Query: 355  ERASPIKMDLAPSKD--------------MGPPKENKKETERA-SPIKMDLAPSKDMGP- 398
            E  SP  + +AP                 + PP  + ++ +   S + +     KD+   
Sbjct: 476  EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV 535

Query: 399  ----------PKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL-- 446
                      P +  +   KD  +L  ++ A  N   S    SS+ ++ LS E  +A   
Sbjct: 536  PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP-SFQSTSSSPEIPLSPEATLAKKS 594

Query: 447  ----------ARDMTLPPETN----VILTK-----DKALPLEAEVAPVKDMAQLPETEIA 487
                      A  MT P   N    VI T      D A PL         +A  P     
Sbjct: 595  LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654

Query: 488  PAKDVAPSTVKEVGLLKDM-SPLSETEMALGKD-----------------------VTPP 523
            PA  VAP+T K         SP  E  ++L                          V P 
Sbjct: 655  PA-GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPS 713

Query: 524  PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 583
            P+     +  + L PE+  ++    +P   T     K   ++  + + P    P    TE
Sbjct: 714  PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773

Query: 584  AT------------------PVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMIS- 624
             +                  P P+      QT++  ++         +G  ++P   +  
Sbjct: 774  DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833

Query: 625  ---PE-TVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSG 680
               PE +++  G K S PA   S      +  P  S  + LS +  G+  P +  P    
Sbjct: 834  SFLPENSLSFQGSKDS-PATTHSPTPPSPKGAPTPSAVTPLSPK--GVTLPPKETP---- 886

Query: 681  TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 740
            T + +  P  KE P +P  K  P  +   +    ++A   P  +P  P+P        K 
Sbjct: 887  TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP--------KG 938

Query: 741  MSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG 800
                    P +P   PA  S + +  P     P P      P  + +P+ PA+ P S  G
Sbjct: 939  APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998

Query: 801  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPK----KPTAIKTEGKPAEVKKMTAKSVP- 855
              +T +     T  AV    P     +T  PK     P A     K +       K  P 
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058

Query: 856  ---ADLSRPK-STSTSSMKKTTT---LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP 908
               A L  PK   +T S+K   T    +  +P  G      K  PMP  P+ TP   K  
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP--PAATPPSPKGG 1116

Query: 909  TSAKP---SSTTPRLSRLAT--NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKK---T 960
             +  P   + TTP  +  +     + P  K   +   +T      P GG A    K   T
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT---PPSPKGGLATPPPKGAPT 1173

Query: 961  EAAATTRKPESNAVTKT--AGPIASAQKQPAGK 991
              AAT   P+    T +    P   A   P+ K
Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 128/553 (23%), Positives = 190/553 (34%), Gaps = 81/553 (14%)

Query: 482  PETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEME 541
            P     P+    P+T    G      P +      G   TPPP       K    PP + 
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGA--PTPPAATPPSPKGSPGTPPP-------KGAPTPPAVT 1339

Query: 542  VALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEA---TPVPIKDMEIAQTQ 598
                +   P L    P +K G  T ++   P       S       TP   K      + 
Sbjct: 1340 PPSPKG-TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398

Query: 599  KGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQP 658
            KG   D    ++  +    AP   ++ E      K    P     V  K   + P  S P
Sbjct: 1399 KG---DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK---KAPATSAP 1452

Query: 659  SELSSETSGIARPE-EGRPVVSGTGNDITTPPNKELPPSPEK-KTKPLATTQPAKTSTSK 716
                    G A P  +G P +        TPP+ + PP+P++  T       PA  +   
Sbjct: 1453 K------GGPATPSSKGDPTLPAV-----TPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 717  AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 776
            A T P  +P  P         + P + +S   P AP     ++   P+ L  K+    P 
Sbjct: 1502 APTLPAVIPSSP--------KEVPATPSSRRDPIAPTAT-LLSKKTPATLAPKEALIPPA 1552

Query: 777  ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST------GPSSRSPSTLL 830
                +P+K  +   P  APA+ S  +++   A T +    A +       P+  SPS   
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 831  PKKPTAI----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG--- 883
               P A+      +G      K T  S P   S  K + TS    T  +  T P A    
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672

Query: 884  ---VVPSRVKATPMPSRPSTTPFID----KKPTSAKPSSTTPRL---------SRLATNT 927
                 P+ +K   +   P +TP I     K P + K S+T+P +         S+   +T
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732

Query: 928  SAP----DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR-------KPESNAVTK 976
             AP     ++   SK    ++  H P G  A  E K     T         KPES +V+ 
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 977  TAGPIASAQKQPA 989
               P  S    P+
Sbjct: 1793 APSPPVSLPLAPS 1805



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 109/425 (25%), Positives = 162/425 (38%), Gaps = 60/425 (14%)

Query: 623  ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ----PSELSSETSGIAR----PEEG 674
            ++P +  GT    +LPA   S   K G   P + +    P+   S   G A     P+ G
Sbjct: 1338 VTPPSPKGTP---TLPATTPS--SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392

Query: 675  RPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ----PAKTSTSKAKTQPTSLPKQPAP 730
             P +     D T+P    +P SP+K      T +    P+K   +     P SL K PA 
Sbjct: 1393 -PAIPSPKGDPTSPA--VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449

Query: 731  TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK--APEKRAS- 787
            +   G    P S     +PA  P  P    A   +  S   K  P   A   AP   A  
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 788  PSKPASAPASRSGSKS----TQTVAKTTTAAAVAS---------TGPS-SRSPSTLLPKK 833
            PS P   PA+ S  +     T T+    T A +A          T PS  ++P+   PK+
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 834  PTAI---KTEGKPAEVKKMTAKSVPA--DLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSR 888
              A    K    P  V   T K  P+  +L  P + ++ S K+  T     P +   P +
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS---PEK 1626

Query: 889  VKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL-KNVRSKVGST--ENI 945
              ATP P    T+P +   P+S K S T+P         + P   K + +K G T  + +
Sbjct: 1627 GPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684

Query: 946  KHQPGGGRAKV----------EKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIV 995
               P      +           KK+ A +    P+ +A   + GP+++    P   VQ  
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744

Query: 996  SKKVS 1000
            S K +
Sbjct: 1745 SSKTA 1749



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 126/550 (22%), Positives = 172/550 (31%), Gaps = 75/550 (13%)

Query: 467  PLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP--- 523
            P      P    A  P     P+    P+T    G    M P +      G   TPP   
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA--PMPPAATPPSPKGGLATPPHKG 1124

Query: 524  -PETEVVLIKN----VCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPP 578
             P T      +    +  PP      T    P      P  K G+ T      P K  P 
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATP------PSPKGGLAT-----PPPKGAP- 1172

Query: 579  LSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLP 638
             +   ATP   K      + KG             G  A P+   +P T   T      P
Sbjct: 1173 -TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-----P 1226

Query: 639  AEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTG-----NDITTPPNKEL 693
            + +  +     +  P     +  S +      P +G P             + TPP+K  
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286

Query: 694  PPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPP 753
            P +P   T P     PA +    A T P + P  P      G    P    +   PA  P
Sbjct: 1287 P-NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-----GSPGTPPPKGAPTPPAVTP 1340

Query: 754  KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTA 813
              P      P+  PS    P        P  +  P+ PA+ P+ + G   T    K   A
Sbjct: 1341 PSPKGTPTLPATTPSSKGGP------TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394

Query: 814  AAVASTGPSSRSPSTLLPKK--PTAIKTEG---------KPAEVKKMTAKSVPADLSRPK 862
                   P+S +   L PKK   T +  EG          P  V  ++ K  PA  +   
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454

Query: 863  STSTSSMKKTTTLSGTAP------------AAGVVPSRVKATPMPSRPSTTPFIDKKPTS 910
              +T S K   TL    P            A    P +  ATP P    T P +   P+S
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV--IPSS 1512

Query: 911  AKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ--PGGGRAKVEKKTEAAATTRK 968
             K    TP   R   +  AP    +  K  +T   K    P        KKT A  T ++
Sbjct: 1513 PKEVPATPSSRR---DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 969  PESNAVTKTA 978
              +   +K A
Sbjct: 1570 APATPSSKEA 1579



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 140/624 (22%), Positives = 208/624 (33%), Gaps = 98/624 (15%)

Query: 335  VLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSK 394
            V+P   + APA  VT       A+P K DL P      P   KK    ++P      PS 
Sbjct: 1407 VIPLSPKKAPATPVT---REGAATPSKGDLTPPAVT--PVSLKKAPATSAPKGGPATPSS 1461

Query: 395  DMGP------PKENKIVPA-KDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVAL- 446
               P      P   K  PA K +   S  + A A           A  V  SS  EV   
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA--VIPSSPKEVPAT 1519

Query: 447  --ARDMTLPPETNVILTKDKAL--PLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGL 502
              +R   + P   ++  K  A   P EA + P   +    +T   P    AP+T      
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP----- 1574

Query: 503  LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDG 562
                   S  E +    VTP         K + +PP +     ++         P  + G
Sbjct: 1575 -------SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627

Query: 563  VLTLANNVTPAKDVPPLSETEATPVPIKDMEIA--------QTQKGISEDSHLESLQDVG 614
              T A   TP    PP++ +     P     +         Q  KG+       +L++V 
Sbjct: 1628 PATPAPKGTPTS--PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685

Query: 615  QSAAP--TFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPE 672
             + AP  T +I+  T  G   K S         +   +    N     LS+       P 
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK----NGSKGPLSTVAPAPLLPV 1741

Query: 673  EGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATT-------QPAKTSTSKAKTQPTSLP 725
            +     +  G D +  P   L P   K + PL          +P   S S A + P SLP
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801

Query: 726  KQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKR 785
              P+P                 VP  PPK+  + S+   +L S     KP+A A   E  
Sbjct: 1802 LAPSP-----------------VPTLPPKQQFLPSSPGLVLESPS---KPLAPADEDE-- 1839

Query: 786  ASPSKPASAPASRSGSKSTQTV---AKTTTAAAVASTGPSSRSPST-------------- 828
                 P   P   SG    Q+V     T  +A +    PS++ P T              
Sbjct: 1840 ---LLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896

Query: 829  LLPKKPTAIKTEGKPAEVKKMTAKSVPAD-LSRPK-STSTSSMKKTTTLSGTAPAAGVVP 886
             +P+      T+    + +   A  +  + +S+ K S S    +K  +  G     GV  
Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTR 1956

Query: 887  SRVKATPMPSRPSTTPFIDKKPTS 910
              ++ +       T P + K P S
Sbjct: 1957 VTIRKSKNILFVITKPDVYKSPAS 1980



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 127/516 (24%), Positives = 187/516 (36%), Gaps = 77/516 (14%)

Query: 522 PPPETEVVLIKNVCLP-PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLS 580
           P   TE V      LP P+ E A+      AL   A L + G  TL    +PA    PLS
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLP-MSSALSVTAALGQPGP-TLPPPCSPAPQQCPLS 59

Query: 581 ET-EATPVPIKDMEIAQTQKGIS--EDSHLESLQDVGQSAAPTFM-------ISPETV-- 628
              +A+P P     IA T   +   + S   +L       APTF+       ISP  +  
Sbjct: 60  AANQASPFP-SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118

Query: 629 -------TGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGT 681
                  T  G   S        L     +K     P+ L+S  S +A  E G  +    
Sbjct: 119 ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPS-VAVAESGSVITLSA 177

Query: 682 G---NDITTPPNK---ELPPSPEKKTKP--LATTQPAKTSTSKAKTQP--TSLPKQPAPT 731
               ++  T  NK   E+ P+P+    P  + +T P    T  A  Q    SLP Q  PT
Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP-QTTPT 236

Query: 732 T---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILP--SKDVKPKPIADAKAPEKRA 786
           T   I     K  +++S L+    P+ P   S +  + P  +  +  + +    + +K A
Sbjct: 237 TTLAIASPQVKDTTISSVLIS---PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293

Query: 787 SPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRS------------------PST 828
            P+ P   P S     +    +   +   +  TGPS+ S                  PS 
Sbjct: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ 353

Query: 829 LLPKKPTAIKTEGKPAEVK--KMTAKSV---PADLSRPKSTSTSSMKKTTTLSGTAPAAG 883
                P   + E  PA V    + A SV   P+ +S    + + S+   T+ S +   + 
Sbjct: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413

Query: 884 VVPSRVKAT-------PMP-SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNV 935
           ++ S   AT        MP S   TTP +   P +   + TT     +AT  S P     
Sbjct: 414 ILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT--TFEVATCVSPPMSSGP 471

Query: 936 RSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPES 971
            S +  T            K E  T+ A T R P S
Sbjct: 472 ISNIEPTSPAALVMAPVAPK-EPSTQVATTLRIPVS 506


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 84/339 (24%), Positives = 122/339 (35%), Gaps = 35/339 (10%)

Query: 653  PCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKT 712
            P  + PS  ++ T+         P ++ T    TTPP    P  P   T    TT P  T
Sbjct: 1417 PPTTTPSPPTTTTTTPPPTTTPSPPITTT----TTPPPTTTPSPPISTT----TTPPPTT 1468

Query: 713  STSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVK 772
            + S   T P+     P+P T       P +      P+ P   P    A  + LP     
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTT-----TPSPPTTTPITPPASTTTLPPTTTP 1523

Query: 773  PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPK 832
              P      P    +PS P + P +     ST T+  TTT +   +T  ++  P T  P 
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPP--TSTTTLPPTTTPSPPPTT--TTTPPPTTTPS 1579

Query: 833  KPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 892
             PT       P+     T    P     P +T+T++   TTT S   P    +      T
Sbjct: 1580 PPTTTT----PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS--PPTTTPITPPTSTT 1633

Query: 893  PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGG 952
             +P  P+TTP      T+  P +TTP  S   T T +P +    +   +T      P   
Sbjct: 1634 TLP--PTTTPSPPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPPTT-----TPSSP 1684

Query: 953  RAKVEKKTEAAATTRKP---ESNAVTKTAGPIASAQKQP 988
                        TT  P    S+ +T T  P ++    P
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 106/452 (23%), Positives = 140/452 (30%), Gaps = 67/452 (14%)

Query: 533  NVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDM 592
            N C P  M+  +T    P      P       TL    TP+      +    T  P   +
Sbjct: 1387 NCCWP--MDKCITTPSPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPI 1442

Query: 593  EIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKC--SLPAEEDSVLEKLGE 650
                T    +  S   S      +  PT   SP T T +      S P    +       
Sbjct: 1443 TTTTTPPPTTTPSPPISTTT---TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT 1499

Query: 651  RKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPA 710
              P  + P    + T+ +       P  + T    TTPP    P  P        TT P 
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTT----TTPPPTTTPSPP--------TTTPI 1547

Query: 711  KTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKD 770
               TS     PT+ P  P  TT       P +          P  P + +  P   P   
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTT----TTPPPTTTPSPPTTTTPSPPTITTTTP---PPTT 1600

Query: 771  VKPKPIADAKAPEKRASPSKPASAPASRSGSKST--------------QTVAKTTTAAAV 816
                P      P    +PS P + P +   S +T               T   TTT +  
Sbjct: 1601 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660

Query: 817  ASTGPS--------------SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862
             +T PS                SP T  P  PT   T   P      T  S     + P 
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT----TTPSSPITTTTTPS 1716

Query: 863  STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 922
            ST+T S   TT    T P+    PS    T M + P TT       T   PS T P  S 
Sbjct: 1717 STTTPSPPPTTM---TTPSPTTTPS-PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772

Query: 923  LATNTSAPDLKNVRSKVGSTENIK---HQPGG 951
             +T T       + +  G  ++ K   H+PGG
Sbjct: 1773 FSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 74/347 (21%), Positives = 122/347 (35%), Gaps = 32/347 (9%)

Query: 654  CNSQPSELSSETSGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAKT 712
            C +QP+ +++ T+    P    P+ + T    T TP   + P +    T    T  P  T
Sbjct: 1878 CVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1937

Query: 713  STSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPS 768
             T    T P    T++   P PT        P++  + + P   P      +  P I  +
Sbjct: 1938 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTT 1996

Query: 769  KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPST 828
              V P P               P + P + +   +T T   T T     +T P + + + 
Sbjct: 1997 TTVTPTPTP--------TGTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTV 2045

Query: 829  LLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAA 882
                 PT  +T           +T    P     P +   T+T+++  T T +GT  P  
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105

Query: 883  GVVPSRVKATPMPS-----RPSTTPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLK 933
              + +    TP P+      P+TTP       +  P+ T   TP  + + T T+  P   
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 934  NVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
               ++  +T  I              T+   TT    +  VT T  P
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 92/433 (21%), Positives = 144/433 (33%), Gaps = 56/433 (12%)

Query: 565  TLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMIS 624
            T   N TP    P  + T  TP P        T   I+  + +        +  PT   +
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TT 1945

Query: 625  PETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGND 684
            P T T T      P          G + P  +  +  ++ T          P  +GT   
Sbjct: 1946 PITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTP--------TPTPTGTQTP 1988

Query: 685  ITTP--PNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
             TTP      + P+P        TT P  T+T+   T PT    Q   TT       P++
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTT-------PIT 2040

Query: 743  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 2088

Query: 803  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 860
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2148

Query: 861  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 911
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 912  KPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR 967
             P+ T   TP  + + T T+  P      ++  +T  I              T+   TT 
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268

Query: 968  KPESNAVTKTAGP 980
               +  VT T  P
Sbjct: 2269 ITTTTTVTPTPTP 2281



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 115/562 (20%), Positives = 175/562 (31%), Gaps = 71/562 (12%)

Query: 453  PPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPLSE 511
            PP T  I T     P      P     Q P T  I     V P+           +P++ 
Sbjct: 1895 PPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949

Query: 512  TEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVT 571
            T       VTP P T          P      +T    P   T+ P      +T    VT
Sbjct: 1950 TTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTTVT 2000

Query: 572  PAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM 622
            P             P  + T  TP P        T   I+  + +        +  PT  
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-- 2058

Query: 623  ISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGRPV 677
             +P T T T      P          G + P  +  +  ++ T     +G   P      
Sbjct: 2059 TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 678  VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTI 733
             + T     TP   + P +    T    T  P  T T    T P    T++   P PT  
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169

Query: 734  GGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPAS 793
                  P++  + + P   P      +  P I  +  V P P               P +
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTT 2220

Query: 794  APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTA 851
             P + +   +T T   T T     +T P + + +      PT  +T           +T 
Sbjct: 2221 TPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 852  KSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTP 902
               P     P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337

Query: 903  FIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEK 958
                   +  P+ T   TP  + + T T+  P      ++  +T  I             
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2397

Query: 959  KTEAAATTRKPESNAVTKTAGP 980
             T+   TT    +  VT T  P
Sbjct: 2398 GTQTPTTTPITTTTTVTPTPTP 2419



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 108/527 (20%), Positives = 161/527 (30%), Gaps = 76/527 (14%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3733 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3788 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3838

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3839 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3898

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3899 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4007

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRA 786
                    P++  + + P   P      +  P I  +  V P P           P    
Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTT 4066

Query: 787  SPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG---PSSRSPSTLLPKKPTAIKTEGKP 843
            +   P   P       +T     TT       TG   P++   +T     PT   T  + 
Sbjct: 4067 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126

Query: 844  AEVKKMTAKSVPADLSRPKST---STSSMKKTTTLSGT-------APAAGVVPSRVKATP 893
                 +T  +       P  T   +T+ +  TTT++ T        P    + +    TP
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186

Query: 894  M----------PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 930
                       P+  ST P  +   ++  P S+TP+ SR   +TS+P
Sbjct: 4187 TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR---STSSP 4230



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 98/484 (20%), Positives = 152/484 (31%), Gaps = 51/484 (10%)

Query: 521  TPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLS 580
            TPP  T +     V   P      T    P   T          T     TP    P  +
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTT-TPITT 1949

Query: 581  ETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAE 640
             T  TP P        T   I+  + +        +  PT   +P T T T      P  
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT- 2006

Query: 641  EDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGRPVVSGTGNDITTPPNKELPP 695
                    G + P  +  +  ++ T     +G   P       + T     TP   + P 
Sbjct: 2007 --------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2058

Query: 696  SPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASGLVPAA 751
            +    T    T  P  T T    T P    T++   P PT        P++  + + P  
Sbjct: 2059 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118

Query: 752  PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 811
             P      +  P I  +  V P P               P + P + +   +T T   T 
Sbjct: 2119 TPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT---TTVTPTPTP 2166

Query: 812  TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSRPKS---TST 866
            T     +T P + + +      PT  +T           +T    P     P +   T+T
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226

Query: 867  SSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSAKPSST---T 917
            +++  T T +GT  P    + +    TP P+      P+TTP       +  P+ T   T
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 918  PRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTK 976
            P  + + T T+  P      ++  +T  I              T+   TT    +  VT 
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 977  TAGP 980
            T  P
Sbjct: 2347 TPTP 2350



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 82/398 (20%), Positives = 115/398 (28%), Gaps = 39/398 (9%)

Query: 461  TKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDV 520
            T    LP     +P       P     P+  +  +T           P +     +    
Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP--------PTTTPSPPISTTT 1462

Query: 521  TPPPETEVVLIKNVCLPPEMEVA---LTEDQVPALKTEAPLAKDGVLTLANNVT--PAKD 575
            TPPP T          PP    +    T    P   T +P     +   A+  T  P   
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522

Query: 576  VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKC 635
              P + T  TP P        T       S          S  PT   +P   T      
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582

Query: 636  SLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGR-----PVVSGTGNDITT--- 687
            +      ++           S P+  ++       P         P  S T    TT   
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642

Query: 688  -PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASG 746
             PP     P P     P  TT P+   T+     PT+ P  P  TT       P +  + 
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT----PSPPTTTMTT 1698

Query: 747  LVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 806
              P   P  P   +  PS   S      P      P    +PS P +         +  T
Sbjct: 1699 PSPTTTPSSPITTTTTPS---STTTPSPPPTTMTTPSPTTTPSPPTT---------TMTT 1746

Query: 807  VAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKP 843
            +  TTT++ + +T  P S +P T  P   T   T   P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 142/741 (19%), Positives = 232/741 (31%), Gaps = 86/741 (11%)

Query: 290  KDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVT 349
            +D +P     MA   + E+     V   + V  PT    ++ +N   PT T +     VT
Sbjct: 1853 EDQKPGGVIPMAFCLNYEI----NVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVT 1908

Query: 350  LLKE-TERASPIKMDLAPSKDMGP-PKENKKETERASPIKMD--LAPSKDMGPPKENKIV 405
                 T   +P    +  +  + P P     +T   +PI     + P+      +     
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968

Query: 406  PAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKA 465
            P      ++           ++T I++   V   + T        T P  T   +T    
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTP--- 2024

Query: 466  LPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPP 524
                    P     Q P T  I     V P+           +P++ T       VTP P
Sbjct: 2025 -------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTP 2072

Query: 525  ETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKD--------- 575
             T          P      +T    P   T+ P      +T    VTP            
Sbjct: 2073 -TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 2128

Query: 576  VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFM-------ISPE-T 627
             P  + T  TP P        T   I+  + +        +  PT         ++P  T
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 628  VTGTGKKCSLPAEEDSVLEKL----GERKPCNSQPSELSSET-----SGIARPEEGRPVV 678
             TGT    + P    + +       G + P  +  +  ++ T     +G   P       
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 679  SGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIG 734
            + T     TP   + P +    T    T  P  T T    T P    T++   P PT   
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2308

Query: 735  GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASA 794
                 P++  + + P   P      +  P I  +  V P P               P + 
Sbjct: 2309 TPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTT 2359

Query: 795  PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAK 852
            P + +   +T T   T T     +T P + + +      PT  +T           +T  
Sbjct: 2360 PITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416

Query: 853  SVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPF 903
              P     P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP 
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476

Query: 904  IDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKVEKK 959
                  +  P+ T   TP  + + T T+  P      ++  +T  I              
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536

Query: 960  TEAAATTRKPESNAVTKTAGP 980
            T+   TT    +  VT T  P
Sbjct: 2537 TQTPTTTPITTTTTVTPTPTP 2557



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2100 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2155 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2205

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2266 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2425

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2426 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTP 2626



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2169 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2224 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2274

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2335 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2444 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2494

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2495 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTP 2695



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2238 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2293 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2343

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2404 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2512

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2513 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2563

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2564 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTP 2764



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2307 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2362 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2412

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2473 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2582 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2632

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2633 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTP 2833



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2376 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2431 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2481

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2542 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2650

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2651 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2701

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2702 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTP 2902



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2445 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2500 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2550

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2611 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2719

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2720 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2770

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2771 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTP 2971



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2514 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2569 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2619

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2680 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2789 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2839

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2840 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTP 3040



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2583 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2638 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2688

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2749 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2857

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2858 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2908

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2909 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTP 3109



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2652 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2707 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2757

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2818 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2927 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 2977

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 2978 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTP 3178



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2721 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2776 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2826

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2887 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2995

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 2996 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3046

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3047 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTP 3247



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2790 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2845 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2895

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 2956 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3064

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3065 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3115

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3116 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTP 3316



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2859 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2914 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 2964

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3025 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3134 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3184

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3185 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTP 3385



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2928 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 2983 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3033

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3094 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3202

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3203 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3253

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3254 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTP 3454



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 2997 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3052 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3102

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3163 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3271

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3272 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3322

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3323 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTP 3523



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3066 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3121 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3171

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3232 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3340

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3341 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3391

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3392 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3448

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTP 3592



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3135 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3190 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3240

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3301 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3409

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3410 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3460

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3461 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTP 3661



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3204 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3259 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3309

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3370 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3478

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3479 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3529

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3530 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTP 3730



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3273 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3328 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3378

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3439 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3547

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3548 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3598

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3599 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTP 3799



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3342 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3397 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3447

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3508 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3667

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3668 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3724

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTP 3868



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3411 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3466 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3516

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3577 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3685

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3686 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3736

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3737 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3793

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3794 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTP 3937



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3480 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3535 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3585

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3645

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3646 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3805

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3806 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3862

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTP 4006



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3549 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3604 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3654

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3714

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3715 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3824 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3874

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3875 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3931

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 3992 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4051

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTP 4075



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 115/564 (20%), Positives = 175/564 (31%), Gaps = 71/564 (12%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3618 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3673 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3723

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3784 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3833 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3892

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3893 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 3943

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 3944 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4000

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 4001 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4060

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS-APDLKNVRSKVGSTENIKHQPGGGRAKV 956
            TP       +  P+ T   TP  + + T T+  P      ++  +T  I           
Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4120

Query: 957  EKKTEAAATTRKPESNAVTKTAGP 980
               T+   TT    +  VT T  P
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTP 4144



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 105/511 (20%), Positives = 160/511 (31%), Gaps = 70/511 (13%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3687 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3742 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3792

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3852

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3853 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3961

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3962 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 4012

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 4013 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4069

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS 928
            TP       +  P+ T   TP  + + T T+
Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 105/511 (20%), Positives = 160/511 (31%), Gaps = 70/511 (13%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3710 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3765 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3815

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3816 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3875

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 3876 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P               P
Sbjct: 3985 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTP 4035

Query: 792  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKM 849
             + P + +   +T T   T T     +T P + + +      PT  +T           +
Sbjct: 4036 TTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4092

Query: 850  TAKSVPADLSRPKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPST 900
            T    P     P +   T+T+++  T T +GT  P    + +    TP P+      P+T
Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4152

Query: 901  TPFIDKKPTSAKPSST---TPRLSRLATNTS 928
            TP       +  P+ T   TP  + + T T+
Sbjct: 4153 TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 112/497 (22%), Positives = 161/497 (32%), Gaps = 71/497 (14%)

Query: 451  TLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE-IAPAKDVAPSTVKEVGLLKDMSPL 509
            T  P T  I T     P      P     Q P T  I     V P+           +P+
Sbjct: 3871 TQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925

Query: 510  SETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANN 569
            + T       VTP P T          P      +T    P   T+ P      +T    
Sbjct: 3926 TTTTT-----VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTP--ITTTTT 3976

Query: 570  VTPAKD---------VPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
            VTP             P  + T  TP P        T   I+  + +        +  PT
Sbjct: 3977 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4036

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-----SGIARPEEGR 675
               +P T T T      P          G + P  +  +  ++ T     +G   P    
Sbjct: 4037 --TTPITTTTTVTPTPTPT---------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPT 731
               + T     TP   + P +    T    T  P  T T    T P    T++   P PT
Sbjct: 4086 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4145

Query: 732  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 791
                    P++  + + P   P      +  P I  +  V P P           +P+  
Sbjct: 4146 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP-----------TPTGT 4193

Query: 792  ASAPASRSGSKSTQTVAKTTTA--AAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM 849
             + P + +   ST  +A+ TT+     +ST  +SRS S+ L +  T + T     E   M
Sbjct: 4194 QTGPPTHT---STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE---M 4247

Query: 850  TAKSVPADLSRPKSTS----TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFID 905
            T+ + P+  + P +TS     S    TTT     P  G       A P PS   TT    
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA-PTPSTVQTTTTSA 4306

Query: 906  KKPTSAKPSSTTPRLSR 922
              PT    S  TP + R
Sbjct: 4307 WTPTPTPLS--TPSIIR 4321



 Score = 30.8 bits (68), Expect = 7.8
 Identities = 96/477 (20%), Positives = 149/477 (31%), Gaps = 80/477 (16%)

Query: 268  TKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVR-WPTET 326
            T T        ++PT   +T    + P+           + PT   +     V   PT T
Sbjct: 3999 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-----GTQTPTTTPITTTTTVTPTPTPT 4053

Query: 327  DVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPI 386
               +     + T T V P    T   +T   +PI      +     P     +T   +PI
Sbjct: 4054 GTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPT---PTPTGTQTPTTTPI 4109

Query: 387  KMD--LAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEV 444
                 + P+      +     P      ++           ++T I++   V   + T  
Sbjct: 4110 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPT 4168

Query: 445  ALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIA----PAKDVAPSTVKEV 500
                  T P  T   +T     P   +  P    +  P  E+     P +   P T +  
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPT-PTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227

Query: 501  GLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAK 560
                  SPL+E+   L                   LPP +E+  T    P     AP   
Sbjct: 4228 S-----SPLTESTTLLST-----------------LPPAIEMTST---APPSTPTAPTTT 4262

Query: 561  DGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPT 620
             G  TL+         PP S T + P            +G +           G S+APT
Sbjct: 4263 SGGHTLS---------PPPSTTTSPP--------GTPTRGTT----------TGSSSAPT 4295

Query: 621  FMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSG 680
                  T T        P    S++   G R   +S         +  A  EE   V +G
Sbjct: 4296 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEE---VYNG 4352

Query: 681  TGNDITTPPNKELPPSPEK-----KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTT 732
            T  D     N  L  + E       + P  T  P+K++ + +K  P+S P +P P T
Sbjct: 4353 TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK--PSSTPSKPTPGT 4407


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 110/460 (23%), Positives = 168/460 (36%), Gaps = 57/460 (12%)

Query: 687  TPPNKELPPSPE------KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK- 739
            +PP   L PS        KK +   +  P   S   A T+  S PK P+     GL++  
Sbjct: 319  SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG 378

Query: 740  -PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 798
             P  L S    + PP         PS++P+ D K  P   A+   K  + S P+ AP  +
Sbjct: 379  PPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQ 437

Query: 799  SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 858
            S    TQ  + ++ AA  AS+ P    P    P K    + EG       +TA + P+  
Sbjct: 438  SFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSS 493

Query: 859  SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTT 917
            S P +TST++       S   P A V        P+P+     PF  +  T A  P++T 
Sbjct: 494  SLPTTTSTTAPTFQPVFSSMGPPASV--------PLPA-----PFFKQTTTPATAPTTTA 540

Query: 918  PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGG------GRAKVEKKTEAAATTRKP-- 969
            P  + LA+ TSA  +  + S   ST++      G        + V   T  A    +P  
Sbjct: 541  PLFTGLASATSA--VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598

Query: 970  ------ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYS-HIQSKCGSKDNIKHVPGGGN 1022
                   + + T   G I    K PA          S S H      +  +     G G+
Sbjct: 599  FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGS 658

Query: 1023 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 1082
                +     S+ +    + +              +  + F   A++ + S       PA
Sbjct: 659  TLATSAPATSSQPTLTFSNTST------------PTFNIPFGSSAKSPLPSYPGANPQPA 706

Query: 1083 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 1122
             GA + +  G+  P    P  G       +A  A APT A
Sbjct: 707  FGAAEGQPPGAAKPAL-APSFGSSFTFGNSAAPAAAPTPA 745



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 99/415 (23%), Positives = 145/415 (34%), Gaps = 50/415 (12%)

Query: 601 ISEDSHLESLQDVGQSAAPTFMISPET--VTGTGKKCSLPAEEDSVLEKLGERKPCNSQP 658
           I++ S   +L     ++ PT +++P T  +  + KK   P       E  G        P
Sbjct: 303 ITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSP 362

Query: 659 SELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAK 718
            +  S    +   + G P +  + +  + PP   L   P     P   T+   T  ++  
Sbjct: 363 PKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETA 422

Query: 719 TQP--TSLPKQPAPTT---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKP 773
           T+P  TS P  PAP      G  N  P S          P  PA +SA P   P     P
Sbjct: 423 TKPQATSAPS-PAPKQSFLFGTQNTSPSS----------PAAPAASSAPPMFKPIFTAPP 471

Query: 774 KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 833
           K   +   P     PS  A+AP+S S   +T T A T           SS  P   +P  
Sbjct: 472 KSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQPVF------SSMGPPASVPLP 522

Query: 834 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSR 888
               K    PA     TA       S   + +  +    +T S + PA G     V  S 
Sbjct: 523 APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582

Query: 889 VKATPMPSRPSTTPFIDKKPTSAKPSST-----------TPRLSRLATNTSAPDLKNVRS 937
           V  T   +  ++ PF+   P ++  S T            P L    T T+     +   
Sbjct: 583 VSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAV 642

Query: 938 KVGSTENIKHQPGGGRAKVEKKTEAAATTRKPE---SNAVTKTAG-PIASAQKQP 988
              ++ +     G G       T A AT+ +P    SN  T T   P  S+ K P
Sbjct: 643 PTATSSSAADFSGFGSTLA---TSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP 694



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 128/601 (21%), Positives = 205/601 (34%), Gaps = 146/601 (24%)

Query: 363 DLAPSKDMGPPKENKKETERASPIKMDLAPSKD------MGPPKENKIVPAKDLVLLSEI 416
           D  P K      ++   +      K+ L PS+         PP+    + A+DL L  + 
Sbjct: 218 DTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKA 277

Query: 417 EVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVK 476
            +   N              AL  +++ A       PP T    T    LP  A  +P  
Sbjct: 278 SLQWFNQ-------------ALEDKSDAASNSVTETPPITQPSFTF--TLPAAAPASP-- 320

Query: 477 DMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCL 536
                P + +AP+ +    ++K++     + P  E+  A   +   PP+T  +L      
Sbjct: 321 -----PTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL------ 369

Query: 537 PPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596
           PP   + L++   P L            TL   + PA  + P ++T+A P          
Sbjct: 370 PP---LGLSQSGPPGLLPSPSFDSKPPTTLLGLI-PAPSMVPATDTKAPPT--------- 416

Query: 597 TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNS 656
                      E+      ++AP+                 PA + S L   G +    S
Sbjct: 417 --------LQAETATKPQATSAPS-----------------PAPKQSFL--FGTQNTSPS 449

Query: 657 QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE----LPPSPE-KKTKPLATTQPAK 711
            P+  ++ ++    P   +P+        T PP  E     PP P    T P +++ P  
Sbjct: 450 SPAAPAASSA----PPMFKPI-------FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTT 498

Query: 712 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV 771
           TST+    QP      P               AS  +PA   K+    +  P+       
Sbjct: 499 TSTTAPTFQPVFSSMGPP--------------ASVPLPAPFFKQTTTPATAPTTTAPLFT 544

Query: 772 KPKPIADAKAPEKRASPSKP-ASAPASRSG--SKSTQTVAKTTTAAAVAST----GPSSR 824
                  A AP   ASPS   AS PA   G  S S+ +V+ TT+ A  AS     G    
Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604

Query: 825 SPSTLLPKKPTAIKTEGKPAEVKKMT-------------------------------AKS 853
           S ++  P   +  +  GKP  +   T                               A S
Sbjct: 605 SAASFTPAMGSIFQF-GKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATS 663

Query: 854 VPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913
            PA  S+P  T +++   T  +   + A   +PS   A P P+  +      + P +AKP
Sbjct: 664 APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKP 720

Query: 914 S 914
           +
Sbjct: 721 A 721


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 78/327 (23%), Positives = 123/327 (37%), Gaps = 37/327 (11%)

Query: 609 SLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETS-- 666
           SL  +  +A+PT      + TGT    SL             RKP  + P+ + S TS  
Sbjct: 375 SLTGLSSTASPTGTPPRASPTGTPSTASLT------------RKPPRASPTGMLSRTSIT 422

Query: 667 ---GIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTS 723
                A P    P  S TG    TPP    P     +  P  T   A  + S +   PT 
Sbjct: 423 KMDSTASPTRTPPRASPTG----TPPRAS-PTGTPSRASPTGTQSTASPTGSPSTASPTG 477

Query: 724 LPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783
            P   +PT  G  ++  ++           +  A  +  PS   S    P   +   +P 
Sbjct: 478 SPSTASPT--GSPSRASLTRTPSRASLTKMESTASITRTPS-RASPTWTPSTASPTGSPS 534

Query: 784 KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPST-LLPKKPTAIKTEGK 842
              +   P+ A  +R+ S+++ T   +  +    S    +R+PST LL + P +    G 
Sbjct: 535 TALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGM 594

Query: 843 PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTP 902
           P+           +    P S   + M  T +++ T P A    +  +A+P  + P  +P
Sbjct: 595 PSRT---------SPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASP 645

Query: 903 FIDKKPTSAKPSSTTPRLSRLATNTSA 929
                P  A P+ T PR S   T + A
Sbjct: 646 --TGTPPRASPTGTPPRASPTGTPSRA 670



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 126/586 (21%), Positives = 207/586 (35%), Gaps = 79/586 (13%)

Query: 426 SSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETE 485
           S T   S   ++++  T  AL    T+P   ++  T     P  A +      A L  T 
Sbjct: 129 SLTTTPSRASLSMTPSTAAAL----TMPSRASLTRT-----PPRASLTMTPSTASLTRTP 179

Query: 486 IAPAKDVAPSTVKEVGL--------LKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLP 537
              +    PS     G+        +   + ++ T        TPP  +          P
Sbjct: 180 PRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGS------P 233

Query: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQT 597
           P   +++       ++T    +  G+L+   ++T       ++ T + P          +
Sbjct: 234 PRASLSMMPSTALLIRTPPRASPTGMLS-RTSLTKMDSTASITRTPSRPSTASPTG-TPS 291

Query: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657
           +  +S      SL  +   A+PT M+S  ++T      S+             R P  + 
Sbjct: 292 RASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASIT---RTPSRAS 348

Query: 658 PSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKA 717
           P+   S  S    P    P  S +   +T   +   P     +  P  T   A  +    
Sbjct: 349 PTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP 408

Query: 718 KTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIA 777
           +  PT +  + + T +                A+P + P  AS  P+  P       P A
Sbjct: 409 RASPTGMLSRTSITKMDST-------------ASPTRTPPRAS--PTGTP-------PRA 446

Query: 778 DAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAI 837
                  RASP+   S  AS +GS ST   + T + +  + TG  SR+  T  P + +  
Sbjct: 447 SPTGTPSRASPTGTQST-ASPTGSPST--ASPTGSPSTASPTGSPSRASLTRTPSRASLT 503

Query: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVV--PSRVKATPMP 895
           K E   A + +  +++ P     P + S +    T    G+   A +   PSR   T  P
Sbjct: 504 KMEST-ASITRTPSRASPT--WTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTP 560

Query: 896 SRPS-TTP------------FIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGST 942
           SR S TTP             + + P SA P+    R S     +SA     + +K+ ST
Sbjct: 561 SRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSA-----LLTKMDST 615

Query: 943 ENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQP 988
            +I   P   RA   +    A+ T  P   + T T  P AS    P
Sbjct: 616 ASITRTP--PRASPTETPPRASPTGTPPRASPTGTP-PRASPTGTP 658



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 88/353 (24%), Positives = 139/353 (39%), Gaps = 36/353 (10%)

Query: 651 RKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQP 709
           R P  +  +   S  S    P     +   +   +T TPP   L  +P   T  L  T P
Sbjct: 123 RSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPS--TASLTRTPP 180

Query: 710 AKTSTSK-AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPS 768
             + T   ++T PT +P   + T +        +L+       PP+     S   + L  
Sbjct: 181 RASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASL-- 238

Query: 769 KDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS-TGPSSRSPS 827
             + P      + P  RASP+   S   S +   ST ++ +T +  + AS TG  SR+  
Sbjct: 239 -SMMPSTALLIRTPP-RASPTGMLSR-TSLTKMDSTASITRTPSRPSTASPTGTPSRASL 295

Query: 828 TLLPKKPTAIKTEGKPAEVKKMTAKSVPAD-LSRPKSTSTSSMKKTTTLSGTAPAAGV-- 884
           ++ P            A + +M  ++ P   LSR   TS + M  T ++S T P A +  
Sbjct: 296 SMTPST----------ASLMRMLPRASPTGMLSR---TSLTKMDSTASISRTPPRASITR 342

Query: 885 VPSRVKATPMPSRPSTTPFIDK-KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 943
            PSR   T  PS  S T    +  PT +  +++   LS  A+ T  P  +   +   ST 
Sbjct: 343 TPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPP-RASPTGTPSTA 401

Query: 944 NIKHQPGG-------GRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPA 989
           ++  +P          R  + K    A+ TR P   + T T  P AS    P+
Sbjct: 402 SLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTP-PRASPTGTPS 453



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 87/380 (22%), Positives = 152/380 (40%), Gaps = 48/380 (12%)

Query: 617 AAPTFMISPETVTGTGKKCSLPAEEDSV-LEKLGERKPCNSQPSELS-----SETSGIAR 670
           A+PT   S  ++TGT  + SL     +  L     R      P   S     S  S +  
Sbjct: 11  ASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVS 70

Query: 671 PEEGRPVVSGTGNDITTPPN----KELPPSPEK-KTKPLATTQPAKTSTSKAKTQPTSLP 725
           P         + + +T  P+    K +PP   + +T P A+    + ST+     P+   
Sbjct: 71  PSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLM-RRPSTASLTRSPSRAS 129

Query: 726 KQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 783
               P+    L+  P + A+  +P  A+  + P  AS   +   +   +  P A      
Sbjct: 130 LTTTPSR-ASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMP 188

Query: 784 KRASPS-KPASAPASRSGSKS--TQTVAK---TTTAAAVASTGPSSRSPSTLLPKKPTAI 837
            R SP+  P++A  ++  S +  T+T+++   T T    + TG   R+  +++P     I
Sbjct: 189 SRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLI 248

Query: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897
           +T  + +    ++  S+       K  ST+S+ +T +   TA   G  PSR   +  PS 
Sbjct: 249 RTPPRASPTGMLSRTSL------TKMDSTASITRTPSRPSTASPTG-TPSRASLSMTPST 301

Query: 898 PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVE 957
            S    + +       +S T  LSR +            +K+ ST +I   P   RA + 
Sbjct: 302 ASLMRMLPR-------ASPTGMLSRTSL-----------TKMDSTASISRTP--PRASIT 341

Query: 958 KKTEAAATTRKPESNAVTKT 977
           +    A+ T KP + + T T
Sbjct: 342 RTPSRASPTGKPSTASPTGT 361


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 84/308 (27%), Positives = 126/308 (40%), Gaps = 30/308 (9%)

Query: 687 TPPNKELPPSPE------KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK- 739
           +PP   L PS        KK +   +  P   S   A T+  S PK P+     GL++  
Sbjct: 319 SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG 378

Query: 740 -PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 798
            P  L S    + PP         PS++P+ D K  P   A+   K  + S P+ AP  +
Sbjct: 379 PPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQ 437

Query: 799 SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 858
           S    TQ  + ++ AA  AS+      P    P K    + EG       +TA + P+  
Sbjct: 438 SFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSS 493

Query: 859 SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTT 917
           S P +TST++       S   P A V        P+P+     PF  +  T A  P++T 
Sbjct: 494 SLPTTTSTTAPTFQPVFSSMGPPASV--------PLPA-----PFFKQTTTPATAPTTTA 540

Query: 918 PRLSRLATNTSAPDLKNVRSKVGSTENI-KHQPGGGRAKVEKKTEAAATTRKPESNAVTK 976
           P  + LA+ TSA  +  + S   ST++  K   G G   V   + +  T+    ++    
Sbjct: 541 PLFTGLASATSA--VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598

Query: 977 TAGPIASA 984
              P ASA
Sbjct: 599 FGAPQASA 606



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 98/414 (23%), Positives = 143/414 (34%), Gaps = 50/414 (12%)

Query: 602 SEDSHLESLQDVGQSAAPTFMISPET--VTGTGKKCSLPAEEDSVLEKLGERKPCNSQPS 659
           ++ S   +L     ++ PT +++P T  +  + KK   P       E  G        P 
Sbjct: 304 TQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPP 363

Query: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT 719
           +  S    +   + G P +  + +  + PP   L   P     P   T+   T  ++  T
Sbjct: 364 KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETAT 423

Query: 720 QP--TSLPKQPAPTT---IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK 774
           +P  TS P  PAP      G  N  P S          P  PA +SA P   P     PK
Sbjct: 424 KPQATSAPS-PAPKQSFLFGTQNTSPSS----------PAAPAASSASPMFKPIFTAPPK 472

Query: 775 PIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKP 834
              +   P     PS  A+AP+S S   +T T A T           SS  P   +P   
Sbjct: 473 SEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQPVF------SSMGPPASVPLPA 523

Query: 835 TAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSRV 889
              K    PA     TA       S   + +  +    +T S + PA G     V  S V
Sbjct: 524 PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV 583

Query: 890 KATPMPSRPSTTPFIDKKPTSAKPSST-----------TPRLSRLATNTSAPDLKNVRSK 938
             T   +  ++ PF+   P ++  S T            P L    T T+          
Sbjct: 584 STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVP 643

Query: 939 VGSTENIKHQPGGGRAKVEKKTEAAATTRKPE---SNAVTKTAG-PIASAQKQP 988
             ++ +     G G       T A AT+ +P    SN  T T   P  S+ K P
Sbjct: 644 TATSSSAADFSGFGSTLA---TSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP 694



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 150/682 (21%), Positives = 229/682 (33%), Gaps = 145/682 (21%)

Query: 363 DLAPSKDMGPPKENKKETERASPIKMDLAPSKD------MGPPKENKIVPAKDLVLLSEI 416
           D  P K      ++   +      K+ L PS+         PP+    + A+DL L  + 
Sbjct: 218 DTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKA 277

Query: 417 EVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVK 476
            +   N              AL  +++ A       PP T    T    LP  A  +P  
Sbjct: 278 SLQWFNQ-------------ALEDKSDAASNSVTETPPTTQPSFTF--TLPAAATASP-- 320

Query: 477 DMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCL 536
                P + +AP+ +    ++K++     + P  E+  A   +   PP+T  +L      
Sbjct: 321 -----PTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL------ 369

Query: 537 PPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQ 596
           PP   + L++   P L            TL   + PA  + P ++T+A P          
Sbjct: 370 PP---LGLSQSGPPGLLPSPSFDSKPPTTLLGLI-PAPSMVPATDTKAPPT--------- 416

Query: 597 TQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNS 656
                      E+      ++AP+                 PA + S L   G +   N+
Sbjct: 417 --------LQAETATKPQATSAPS-----------------PAPKQSFL--FGTQ---NT 446

Query: 657 QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE----LPPSPE-KKTKPLATTQPAK 711
            PS  ++  +  A P   +P+        T PP  E     PP P    T P +++ P  
Sbjct: 447 SPSSPAAPAASSASPMF-KPI-------FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTT 498

Query: 712 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV 771
           TST+    QP      P               AS  +PA   K+    +  P+       
Sbjct: 499 TSTTAPTFQPVFSSMGPP--------------ASVPLPAPFFKQTTTPATAPTTTAPLFT 544

Query: 772 KPKPIADAKAPEKRASPSKP-ASAPASRSG--SKSTQTVAKTTTAAAVAST----GPSSR 824
                  A AP   ASPS   AS PA   G  S S+ +V+ TT+ A  AS     G    
Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604

Query: 825 SPSTLLPK--------KPTAIKT--------EGKPAEVKKMT--------------AKSV 854
           S ++  P         KP A+ T        +  P  V   T              A S 
Sbjct: 605 SAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSA 664

Query: 855 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 914
           PA  S+P  T +++   T  +   + A   +PS   A P P+  +      + P +AKP+
Sbjct: 665 PATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKPA 721

Query: 915 STTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAV 974
            T    S      SA               IK  P      ++  T   AT       A 
Sbjct: 722 LTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQ-PTFGGATHSAFGLKAT 780

Query: 975 TKTAGPIASAQKQPAGKVQIVS 996
               G  AS+Q    G   + S
Sbjct: 781 ASAFGAPASSQPAFGGSTAVFS 802


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 119/546 (21%), Positives = 188/546 (34%), Gaps = 76/546 (13%)

Query: 483 ETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGK--DVTPPPETEVVLIKNVCLPPEM 540
           ET++     V P+ VK   +    SP  +   A GK  DVTP        +K   LPP  
Sbjct: 209 ETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ-------VKGGALPPAK 261

Query: 541 -------------EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP- 586
                        E + +E++ PA       A + +L +     PAK  P    T A P 
Sbjct: 262 RAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPG 321

Query: 587 ------------VPIKDMEIAQTQKGISEDSHLES-----------LQDVGQSAAPTFMI 623
                        P +D E +  +   SE+    +              VG ++AP    
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381

Query: 624 SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
             +         + PA   +   K  E    +S+ S+   E    A+P    P V     
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441

Query: 684 DITTPPNKELPPSPEKKTKPLAT-TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
                P K   P+P +KT P A   Q  K       +   S   + A   +     KP+ 
Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
            +  + PA+      +      + P K     P A     E+ +  S   S+ +S     
Sbjct: 502 KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD---- 557

Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862
                 +  TA A A      +S   +L  KPT+   +G P   +K    +V     +P 
Sbjct: 558 -----GEVPTAVAPA----QEKSLGNILQAKPTSSPAKGPP---QKAGPVAVQVKAEKPM 605

Query: 863 STSTSSMKKTTTL-SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921
             S SS + + +  S  APAA    +  +A P    P T     K  T+A     + +++
Sbjct: 606 DNSESSEESSDSADSEEAPAA---MTAAQAKPALKIPQTKACPKKTNTTA-----SAKVA 657

Query: 922 RLATNTSAP-DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
            +   T AP       S  GS+  +    GG +   E  + +  +  + E   +  T G 
Sbjct: 658 PVRVGTQAPRKAGTATSPAGSSPAV---AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 714

Query: 981 IASAQK 986
             S  K
Sbjct: 715 AKSVGK 720



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 175/850 (20%), Positives = 301/850 (35%), Gaps = 131/850 (15%)

Query: 157 SATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAE-PPQP 215
           S++ DTS  + + D ++    + P       +  SV    SP  ++  +P  V +  PQ 
Sbjct: 198 SSSEDTSSSSDETD-VEGKPSVKPAQV----KASSVSTKESPARKAAPAPGKVGDVTPQV 252

Query: 216 TAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALA 275
               L  AK  +   EE   ++      G ++ + AP+       A +  L  +   A A
Sbjct: 253 KGGALPPAKRAKKPEEESESSEE-----GSESEEEAPAGTRSQVKASEKILQVRAASAPA 307

Query: 276 KDMES-------PTKLDVTLAKDMQPSMESDM------ALVKDMELPTEKEVALVKDVRW 322
           K           P K     ++      E D       +   + E P  K +   K    
Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK 367

Query: 323 PTETDVSSA-------KNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKE 375
            ++   +SA       K        +  PA       + E  S    + + S++  P + 
Sbjct: 368 TSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQA 427

Query: 376 NKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVA-QANDIISSTEISSAE 434
             K + +A  ++   AP+K+          P K     ++++V  Q  D  SS+E S ++
Sbjct: 428 --KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485

Query: 435 KVALSSETEVA---LARDMTLPPETNV---ILTKDKALPLEAEVAPVKDMAQLPE----- 483
           + AL++        L +   + P + +    L K        +V P    AQ+ +     
Sbjct: 486 REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545

Query: 484 ----TEIAPAKD------VAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIK- 532
                E + + D      VAP+  K +G +    P S           PP +   V ++ 
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG------PPQKAGPVAVQV 599

Query: 533 NVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDM 592
               P +   +  E    A   EAP A       A    PA  +P   +T+A P   K  
Sbjct: 600 KAEKPMDNSESSEESSDSADSEEAPAAMT-----AAQAKPALKIP---QTKACP---KKT 648

Query: 593 EIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERK 652
               + K        ++ +  G + +P    SP    GT +    PAE+ S         
Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGS-SPAVAGGTQR----PAEDSS--------- 694

Query: 653 PCNSQPSELSSETSGIA-RPEEGRPVVSGTGNDITTPPNKE-----LPPSPEKKTKPLAT 706
             +S+ S+   E +G+A    + + V  G      + P K        P    KT P  T
Sbjct: 695 --SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752

Query: 707 TQPAKTSTSKAKTQPTSLPKQPA--PTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 764
              A+       ++  S  ++ A  P  +    KK  + A+     AP  +  +++    
Sbjct: 753 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA---- 808

Query: 765 ILPSKDVKPKPIADAKAPEKRASPSK-PASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 823
             P K V     A  ++P K   P + P ++     G  S  +V K    AA A TGP  
Sbjct: 809 --PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE 866

Query: 824 RSPS------------TLLPKKPTA----IKTEGKPA-EVKKMTAKSVPADLSRPKSTST 866
            S S            TL   KP+     I+    PA E  +  A   P   + P +   
Sbjct: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 926

Query: 867 SSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST--------TP 918
                + + S  + + G  P+ V +  +   P    F+D   + A P++T        TP
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI--FVDPNRSPAGPAATPAQAQAASTP 984

Query: 919 RLSRLATNTS 928
           R +R + +T+
Sbjct: 985 RKARASESTA 994



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 87/404 (21%), Positives = 136/404 (33%), Gaps = 27/404 (6%)

Query: 617  AAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-SGIARPEEGR 675
            A P    +  +V G     S+  +  +  EK G  K  NS P   + +T + +   +  R
Sbjct: 101  ATPRLASTNSSVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPR 158

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG 735
                 + N       +E    P       A  +P   S  +A +           T + G
Sbjct: 159  KSAEPSANTTLVSETEEEGSVPAFG----AAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214

Query: 736  LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 795
              K  +  A     +   K      A P+     DV P+    A  P KRA   +  S  
Sbjct: 215  --KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE- 271

Query: 796  ASRSGSKSTQTVAKTTTAAAVASTG----PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851
            +S  GS+S +     T +   AS       ++ +P+   P K       GK   V   T 
Sbjct: 272  SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 331

Query: 852  KSVPADLSRPKSTSTSSMKKTTTLSGT---APAAGVVPSRVKATPMPSRPSTTPFIDKKP 908
               P + S   S  +S  ++ T  +     A A+G   S+V A   P++ S      K  
Sbjct: 332  AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT-SQVGAASAPAKESPR----KGA 386

Query: 909  TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRK 968
              A P  T P +++        D     S+  S E+   +    +AK   K         
Sbjct: 387  APAPPGKTGPAVAKAQAGKREED-----SQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441

Query: 969  PESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKD 1012
            P   +  K A P    +  PA     V K+   S   S+    D
Sbjct: 442  PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 159/813 (19%), Positives = 278/813 (34%), Gaps = 106/813 (13%)

Query: 190  WSVEALNSPHSESFVS----PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGL 245
            W  ++ +S    S  S    P AVA P Q  ++   L  +   +  + PP +A  + + +
Sbjct: 541  WEEDSESSSEESSDSSDGEVPTAVA-PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599

Query: 246  K----------TTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPS 295
            K          + + + S ++E A A   A   K  + + +    P K + T +  + P 
Sbjct: 600  KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659

Query: 296  MESDMALVK--DMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA----PAKDVT 349
                 A  K      P     A+    + P E   SS ++     +T +A     AK V 
Sbjct: 660  RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG 719

Query: 350  LLKETERAS-PIKMDLAP-SKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPA 407
               + + AS P+K  L   +  + P K     T+  +  + D   S++    +E    PA
Sbjct: 720  KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA 779

Query: 408  KDLVLLSEIEV----AQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN-----V 458
            +    + + +     A A    +   IS+  KV  ++      +     PP  N     V
Sbjct: 780  QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839

Query: 459  ILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMAL-- 516
            +     ++P   +       AQ    E + + +    + +E   L  + P  +T      
Sbjct: 840  LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899

Query: 517  ----------GKDVTPPPETEVVLI---KNVCLPPEMEVALTEDQVPALKTEAPLAKDGV 563
                      G   TPP +T        K        E + ++ + PA  T A + K  +
Sbjct: 900  LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959

Query: 564  LTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMI 623
            + +  N +PA      ++ +A   P K      T +  S +S  E +    Q   P    
Sbjct: 960  IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019

Query: 624  SPETV------------------------TGTGKKCSLPAEE-DSVLEKLGERKPCNS-- 656
            +  T+                           GKK   PA + DS +  L    P ++  
Sbjct: 1020 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV 1079

Query: 657  --------QPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQ 708
                    +  +L         PE        + +   +  + E  P   K    L    
Sbjct: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE-GPQGAKSAHTLVGPT 1138

Query: 709  PAKTSTSKAKTQPTSLPKQ---PAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSI 765
            P++T T   +T   S       P+ + + G     ++ A+     A PK  +  S   S 
Sbjct: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV-SST 1197

Query: 766  LPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA--VASTGPSS 823
            L +KD  P    +AK P++ A    P +     +   + Q   K    A    AST    
Sbjct: 1198 LAAKD-DPDGKQEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQ 1255

Query: 824  RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKK-----TTTLSGT 878
             + +  L  +P  +      A V K+  + +  +  +   T+  S +K        LSG 
Sbjct: 1256 SNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGD 1315

Query: 879  APAAGVVPSRVK----------ATPMPSRPSTT 901
             PAA    S+ K          A+  P + STT
Sbjct: 1316 QPAARTPRSKKKKKLGAGEGGEASVSPEKTSTT 1348


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 119/546 (21%), Positives = 188/546 (34%), Gaps = 76/546 (13%)

Query: 483 ETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGK--DVTPPPETEVVLIKNVCLPPEM 540
           ET++     V P+ VK   +    SP  +   A GK  DVTP        +K   LPP  
Sbjct: 209 ETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ-------VKGGALPPAK 261

Query: 541 -------------EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATP- 586
                        E + +E++ PA       A + +L +     PAK  P    T A P 
Sbjct: 262 RAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPG 321

Query: 587 ------------VPIKDMEIAQTQKGISEDSHLES-----------LQDVGQSAAPTFMI 623
                        P +D E +  +   SE+    +              VG ++AP    
Sbjct: 322 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 381

Query: 624 SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
             +         + PA   +   K  E    +S+ S+   E    A+P    P V     
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441

Query: 684 DITTPPNKELPPSPEKKTKPLAT-TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 742
                P K   P+P +KT P A   Q  K       +   S   + A   +     KP+ 
Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
            +  + PA+      +      + P K     P A     E+ +  S   S+ +S     
Sbjct: 502 KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD---- 557

Query: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 862
                 +  TA A A      +S   +L  KPT+   +G P   +K    +V     +P 
Sbjct: 558 -----GEVPTAVAPA----QEKSLGNILQAKPTSSPAKGPP---QKAGPVAVQVKAEKPM 605

Query: 863 STSTSSMKKTTTL-SGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921
             S SS + + +  S  APAA    +  +A P    P T     K  T+A     + +++
Sbjct: 606 DNSESSEESSDSADSEEAPAA---MTAAQAKPALKIPQTKACPKKTNTTA-----SAKVA 657

Query: 922 RLATNTSAP-DLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
            +   T AP       S  GS+  +    GG +   E  + +  +  + E   +  T G 
Sbjct: 658 PVRVGTQAPRKAGTATSPAGSSPAV---AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 714

Query: 981 IASAQK 986
             S  K
Sbjct: 715 AKSVGK 720



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 186/948 (19%), Positives = 324/948 (34%), Gaps = 121/948 (12%)

Query: 190  WSVEALNSPHSESFVS----PEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGL 245
            W  ++ +S    S  S    P AVA P Q  ++   L  +   +  + PP +A  + + +
Sbjct: 541  WEEDSESSSEESSDSSDGEVPTAVA-PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599

Query: 246  K----------TTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPS 295
            K          + + + S ++E A A   A   K  + + +    P K + T +  + P 
Sbjct: 600  KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 659

Query: 296  MESDMALVK--DMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA----PAKDVT 349
                 A  K      P     A+    + P E   SS ++     +T +A     AK V 
Sbjct: 660  RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG 719

Query: 350  LLKETERAS-PIKMDLAP-SKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPA 407
               + + AS P+K  L   +  + P K     T+  +  + D   S++    +E    PA
Sbjct: 720  KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA 779

Query: 408  KDLVLLSEIEV----AQANDIISSTEISSAEKVALSSETEVALARDMTLPPETN-----V 458
            +    + + +     A A    +   IS+  KV  ++      +     PP  N     V
Sbjct: 780  QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839

Query: 459  ILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMAL-- 516
            +     ++P   +       AQ    E + + +    + +E   L  + P  +T      
Sbjct: 840  LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899

Query: 517  ----------GKDVTPPPETEVVLI---KNVCLPPEMEVALTEDQVPALKTEAPLAKDGV 563
                      G   TPP +T        K        E + ++ + PA  T A + K  +
Sbjct: 900  LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959

Query: 564  LTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMI 623
            + +  N +PA      ++ +A   P K      T +  S +S  E +    Q   P    
Sbjct: 960  IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019

Query: 624  SPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683
            +  T         +P     +  K       +S+ S   S+     + +EG        N
Sbjct: 1020 NVVT---------MPTAHPRIAPKASMAGASSSKESSRISD----GKKQEGPATQVSKKN 1066

Query: 684  DITTPPN----KELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK 739
              + P      K L     +   P+A TQP+    S   T P + P Q       G NK 
Sbjct: 1067 PASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSP-QSTSVQAKGTNK- 1124

Query: 740  PMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 799
                         PK P V  A  +   S D +    + + + E    P    SA     
Sbjct: 1125 ----------LRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174

Query: 800  GSKSTQTVAKTTTAAAVAS--TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 857
                T+T+ + T A +       PS    S  +    T   ++   A  K  ++ SV + 
Sbjct: 1175 TPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSST 1234

Query: 858  LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 917
            L+           K         AAG++  +       S   TTP   +KP   K  +  
Sbjct: 1235 LAAKDDPDGKQEAK------PQQAAGMLSPKTGGKEAAS--GTTPQKSRKP---KKGAGN 1283

Query: 918  PRLSRLATNTSAPD--------LKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKP 969
            P+ S LA  ++           L   + +    + +       R KV   T+   ++RK 
Sbjct: 1284 PQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK--ESSRKG 1341

Query: 970  ESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKK 1029
              +   K +G       QPA +     KK        K G+ +       GG   +  +K
Sbjct: 1342 WESRKRKLSG------DQPAARTPRSKKK-------KKLGAGE-------GGEASVSPEK 1381

Query: 1030 VDISKVSSKCGSKA--NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLD 1075
               +        KA  ++K K G G +  +  K   +E+ Q  +G+++
Sbjct: 1382 TSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE 1429



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 87/404 (21%), Positives = 136/404 (33%), Gaps = 27/404 (6%)

Query: 617  AAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSET-SGIARPEEGR 675
            A P    +  +V G     S+  +  +  EK G  K  NS P   + +T + +   +  R
Sbjct: 101  ATPRLASTNSSVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPR 158

Query: 676  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG 735
                 + N       +E    P       A  +P   S  +A +           T + G
Sbjct: 159  KSAEPSANTTLVSETEEEGSVPAFG----AAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214

Query: 736  LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 795
              K  +  A     +   K      A P+     DV P+    A  P KRA   +  S  
Sbjct: 215  --KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE- 271

Query: 796  ASRSGSKSTQTVAKTTTAAAVASTG----PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 851
            +S  GS+S +     T +   AS       ++ +P+   P K       GK   V   T 
Sbjct: 272  SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 331

Query: 852  KSVPADLSRPKSTSTSSMKKTTTLSGT---APAAGVVPSRVKATPMPSRPSTTPFIDKKP 908
               P + S   S  +S  ++ T  +     A A+G   S+V A   P++ S      K  
Sbjct: 332  AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT-SQVGAASAPAKESPR----KGA 386

Query: 909  TSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRK 968
              A P  T P +++        D     S+  S E+   +    +AK   K         
Sbjct: 387  APAPPGKTGPAVAKAQAGKREED-----SQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441

Query: 969  PESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKD 1012
            P   +  K A P    +  PA     V K+   S   S+    D
Sbjct: 442  PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.123    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,761,688
Number of Sequences: 37866
Number of extensions: 2769982
Number of successful extensions: 19907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 1329
Number of HSP's that attempted gapping in prelim test: 10404
Number of HSP's gapped (non-prelim): 5459
length of query: 1152
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1039
effective length of database: 13,968,660
effective search space: 14513437740
effective search space used: 14513437740
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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