Guide to the Human Genome
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Search of human proteins with 46488921

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46488921 astrotactin isoform 2 [Homo sapiens]
         (1216 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46488923 astrotactin isoform 1 [Homo sapiens]                     2508   0.0  
gi|46488921 astrotactin isoform 2 [Homo sapiens]                     2508   0.0  
gi|46488919 astrotactin 2 isoform c [Homo sapiens]                   1233   0.0  
gi|46488917 astrotactin 2 isoform b [Homo sapiens]                   1223   0.0  
gi|46488915 astrotactin 2 isoform a [Homo sapiens]                   1199   0.0  
gi|239755157 PREDICTED: similar to astrotactin 2 [Homo sapiens]       365   e-100
gi|38016949 astrotactin 2 isoform d [Homo sapiens]                    325   1e-88
gi|10190748 CEGP1 protein [Homo sapiens]                               52   3e-06
gi|4507483 thrombomodulin precursor [Homo sapiens]                     51   8e-06
gi|93102379 low density lipoprotein-related protein 1B precursor...    50   1e-05
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]     50   1e-05
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                48   5e-05
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       47   1e-04
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]      46   2e-04
gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo sa...    45   3e-04
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa...    43   0.002
gi|126012562 low density lipoprotein-related protein 1 [Homo sap...    43   0.002
gi|61743980 stabilin 2 precursor [Homo sapiens]                        42   0.003
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    41   0.006
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       40   0.018
gi|21704279 jagged 2 isoform b precursor [Homo sapiens]                39   0.039
gi|21704277 jagged 2 isoform a precursor [Homo sapiens]                39   0.039
gi|24430141 fibrillin 1 precursor [Homo sapiens]                       38   0.067
gi|46249414 latent transforming growth factor beta binding prote...    38   0.067
gi|46249412 latent transforming growth factor beta binding prote...    38   0.067
gi|157384998 low density lipoprotein receptor-related protein 4 ...    38   0.067
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]          37   0.15 
gi|22547221 tolloid-like 1 [Homo sapiens]                              37   0.15 
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]         37   0.15 
gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]            36   0.20 

>gi|46488923 astrotactin isoform 1 [Homo sapiens]
          Length = 1294

 Score = 2508 bits (6499), Expect = 0.0
 Identities = 1216/1216 (100%), Positives = 1216/1216 (100%)

Query: 1    MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS 60
            MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS
Sbjct: 1    MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS 60

Query: 61   ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF 120
            ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF
Sbjct: 61   ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF 120

Query: 121  HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW 180
            HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW
Sbjct: 121  HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW 180

Query: 181  CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD 240
            CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD
Sbjct: 181  CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD 240

Query: 241  GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK 300
            GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK
Sbjct: 241  GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK 300

Query: 301  YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT 360
            YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT
Sbjct: 301  YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT 360

Query: 361  FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL 420
            FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL
Sbjct: 361  FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL 420

Query: 421  IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG 480
            IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG
Sbjct: 421  IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG 480

Query: 481  ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE 540
            ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE
Sbjct: 481  ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE 540

Query: 541  GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP 600
            GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP
Sbjct: 541  GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP 600

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
            VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC
Sbjct: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660

Query: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM 720
            EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM
Sbjct: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM 720

Query: 721  NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE 780
            NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE
Sbjct: 721  NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE 780

Query: 781  ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT 840
            ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT
Sbjct: 781  ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT 840

Query: 841  SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE 900
            SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE
Sbjct: 841  SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE 900

Query: 901  RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL 960
            RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL
Sbjct: 901  RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL 960

Query: 961  LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP 1020
            LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP
Sbjct: 961  LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP 1020

Query: 1021 LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS 1080
            LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS
Sbjct: 1021 LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS 1080

Query: 1081 FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI 1140
            FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI
Sbjct: 1081 FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI 1140

Query: 1141 VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE 1200
            VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE
Sbjct: 1141 VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE 1200

Query: 1201 SFGEFTWRCEDELGPR 1216
            SFGEFTWRCEDELGPR
Sbjct: 1201 SFGEFTWRCEDELGPR 1216


>gi|46488921 astrotactin isoform 2 [Homo sapiens]
          Length = 1216

 Score = 2508 bits (6499), Expect = 0.0
 Identities = 1216/1216 (100%), Positives = 1216/1216 (100%)

Query: 1    MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS 60
            MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS
Sbjct: 1    MALAGLCALLACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPS 60

Query: 61   ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF 120
            ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF
Sbjct: 61   ASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLF 120

Query: 121  HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW 180
            HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW
Sbjct: 121  HIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRW 180

Query: 181  CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD 240
            CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD
Sbjct: 181  CKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILD 240

Query: 241  GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK 300
            GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK
Sbjct: 241  GYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNK 300

Query: 301  YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT 360
            YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT
Sbjct: 301  YKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLT 360

Query: 361  FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL 420
            FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL
Sbjct: 361  FYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNCPLVVKITLHVPEHL 420

Query: 421  IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG 480
            IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG
Sbjct: 421  IADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETG 480

Query: 481  ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE 540
            ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE
Sbjct: 481  ECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGE 540

Query: 541  GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP 600
            GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP
Sbjct: 541  GMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGP 600

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
            VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC
Sbjct: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660

Query: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM 720
            EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM
Sbjct: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPM 720

Query: 721  NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE 780
            NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE
Sbjct: 721  NQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGLVVATVPLENQCLEE 780

Query: 781  ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT 840
            ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT
Sbjct: 781  ISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAISQALSNALHSLDGAT 840

Query: 841  SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE 900
            SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE
Sbjct: 841  SRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEE 900

Query: 901  RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL 960
            RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL
Sbjct: 901  RERDPKVLTFPEYITSLSDSGTKHMAAGVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVL 960

Query: 961  LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP 1020
            LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP
Sbjct: 961  LEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAP 1020

Query: 1021 LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS 1080
            LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS
Sbjct: 1021 LPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLS 1080

Query: 1081 FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI 1140
            FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI
Sbjct: 1081 FVDDIISGAKSPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVI 1140

Query: 1141 VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE 1200
            VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE
Sbjct: 1141 VKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYE 1200

Query: 1201 SFGEFTWRCEDELGPR 1216
            SFGEFTWRCEDELGPR
Sbjct: 1201 SFGEFTWRCEDELGPR 1216


>gi|46488919 astrotactin 2 isoform c [Homo sapiens]
          Length = 1339

 Score = 1233 bits (3191), Expect = 0.0
 Identities = 622/1240 (50%), Positives = 829/1240 (66%), Gaps = 63/1240 (5%)

Query: 16   PAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDL------------------SIMH 57
            P    ATAA   +P     C+LK++TVS LP LRE+D+                  +   
Sbjct: 46   PLLAGATAAASREPDSP--CRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAGAAAAAA 103

Query: 58   SP-------SASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQ 110
            SP       +A+E +LL  VRN+ PG + V DDL+NTELP+F LE+SG   DI LV WRQ
Sbjct: 104  SPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQ 163

Query: 111  QWLENGTLLFHIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCL 170
            QWLENGTL FH+             PT +   E  EE++ ILHISVMGG+IALLL +L  
Sbjct: 164  QWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVF 223

Query: 171  VMILYTRRRWCKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGT 230
             + LY +RRW KRRR+  PQKSAS EA +EIHYIPSVL+G   RES R++R+Q HNS   
Sbjct: 224  TVALYAQRRWQKRRRI--PQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIG 281

Query: 231  LSIRETPILDGYEYDITD----LRHHLQRECMNGGEDFASQVTRTLDSLQGCNEK----S 282
            + IRETPILD Y+ +  +      +H+ RE     ++F SQVT TLDSL    E+     
Sbjct: 282  VPIRETPILDDYDCEEDEEPPRRANHVSRE-----DEFGSQVTHTLDSLGHPGEEKVDFE 336

Query: 283  GMDLTPGSDNAKLSLMNKYKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAF 342
                   +     SLM K+K++  A +P++    Q  L S TS+ +RKR  +K+R G +F
Sbjct: 337  KKAAAEATQETVESLMQKFKESFRANTPIEIGQLQPPLRS-TSAGKRKR-RSKSRGGISF 394

Query: 343  LNPEGDSGTEAENDPQLTFYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSS 402
               +G SG+EA+++ QLTFYT+  RSRRRS+ G  +SPVNKT LTLI+++SC++ +VC S
Sbjct: 395  GRAKGTSGSEADDETQLTFYTEQYRSRRRSK-GLLKSPVNKTALTLIAVSSCILAMVCGS 453

Query: 403  HVNCPLVVKITLHVPEHLIADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDL 462
             ++CPL VK+TLHVPEH IADGS F++ EGS LD SDWLNPA++ L+ Q N++ PW  DL
Sbjct: 454  QMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDL 513

Query: 463  CARRLLDPCEHQCDPETGECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLV 522
            C +R  D CE  CDPETGEC C+EGY  DPVH+HLC+R++WG ++GPWPYT  +RG+DLV
Sbjct: 514  CGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLV 573

Query: 523  LGEQPSDKIFRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREEL 582
             GEQ  +KI R T++LG+G+WLP+SKSFV+PP EL+INP A CKTD+ V ED  +VREE 
Sbjct: 574  TGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEA 633

Query: 583  MTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSG 642
            M S+ F+++  LL SFGPVRDCS++NGGC++NF+C+SDR++DS+GCVCP  L PMKD SG
Sbjct: 634  MLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSG 693

Query: 643  CYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI 702
            CYD   G+DCSDGFNGGCEQLCLQQ  P P D T   I MFCGC+E+YKL  DG+SC ++
Sbjct: 694  CYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLML 753

Query: 703  TETCPEGSDCGESRELPMNQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQL 762
            ++ C EG  C +  +   N TLFGEM  GYNN ++ V  GQV + TFR+NNF +    QL
Sbjct: 754  SDVC-EGPKCLKP-DSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDF-PQL 810

Query: 763  PDGLVVATVPLENQCLEEISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQ 822
             DGL+V  +P+E QC   +SEP PD   LTG + + E  GYP++Q W+VRS +Y +KL+ 
Sbjct: 811  ADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLST 870

Query: 823  VAISQALSNALHSLDGATSRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLW 882
            + ++   +N L  L   +SR + ++ +  +G+HYI EA+YG E +C I +P+K+VQ++LW
Sbjct: 871  ITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLW 930

Query: 883  LEYEDISKGNSPSDESEERERDPKVLTFPEYITS--LSDSGTKHMAAGVRMECHSKGRCP 940
            L+Y+   K  +     +E +  P +      +T+  LSD     + +GV + C  KGRCP
Sbjct: 931  LQYQ---KETTELGSKKELKSMPFITYLSGLLTAQMLSDD---QLISGVEIRCEEKGRCP 984

Query: 941  SSCPLCHVTSSPDTPAEPVLLEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIE 1000
            S+C LC           PVLLE+ +  P+Y L+ +N T+   + A MSS WCSG GDVI+
Sbjct: 985  STCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVID 1044

Query: 1001 DWCRCDSTAFGADGLPTCAPLPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLR 1060
            DWCRCD +AF A+GLP C+PL QPVLRLS   EPSST+V LEW   +P IG ++ DY+L+
Sbjct: 1045 DWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQ 1104

Query: 1061 QEKVTDRMDHSKVETETVLSFVDDIISGAKSPCAMP----SQVPDKQLTTISLIIRCLEP 1116
             +KV +  D + + T   LSF DD++SG  + C        +VP  +++  S+I +CLEP
Sbjct: 1105 HKKVDEYTD-TDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVP--EVSIYSVIFKCLEP 1161

Query: 1117 DTIYMFTLWGVDNTGRRSRPSDVIVKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTA 1176
            D +Y FTL+ VD  GR S  S V ++T CP+VDD KA+EIADKIYNL+NGYTSGKEQQ A
Sbjct: 1162 DGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMA 1221

Query: 1177 YNTLLDLGSPTLHRVLYHYNQHYESFGEFTWRCEDELGPR 1216
            YNTL+++ +  L RV +HYN HYE FG+F WR EDELGPR
Sbjct: 1222 YNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPR 1261


>gi|46488917 astrotactin 2 isoform b [Homo sapiens]
          Length = 1335

 Score = 1223 bits (3165), Expect = 0.0
 Identities = 620/1240 (50%), Positives = 826/1240 (66%), Gaps = 67/1240 (5%)

Query: 16   PAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDL------------------SIMH 57
            P    ATAA   +P     C+LK++TVS LP LRE+D+                  +   
Sbjct: 46   PLLAGATAAASREPDSP--CRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAGAAAAAA 103

Query: 58   SP-------SASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQ 110
            SP       +A+E +LL  VRN+ PG + V DDL+NTELP+F LE+SG   DI LV WRQ
Sbjct: 104  SPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQ 163

Query: 111  QWLENGTLLFHIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCL 170
            QWLENGTL FH+             PT +   E  EE++ ILHISVMGG+IALLL +L  
Sbjct: 164  QWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVF 223

Query: 171  VMILYTRRRWCKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGT 230
             + LY +RRW KRRR+  PQKSAS EA +EIHYIPSVL+G   RES R++R+Q HNS   
Sbjct: 224  TVALYAQRRWQKRRRI--PQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIG 281

Query: 231  LSIRETPILDGYEYDITD----LRHHLQRECMNGGEDFASQVTRTLDSLQGCNEK----S 282
            + IRETPILD Y+ +  +      +H+ RE     ++F SQVT TLDSL    E+     
Sbjct: 282  VPIRETPILDDYDCEEDEEPPRRANHVSRE-----DEFGSQVTHTLDSLGHPGEEKVDFE 336

Query: 283  GMDLTPGSDNAKLSLMNKYKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAF 342
                   +     SLM K+K++  A +P++    Q  L S TS+ +RKR  +K+R G +F
Sbjct: 337  KKAAAEATQETVESLMQKFKESFRANTPIEIGQLQPPLRS-TSAGKRKR-RSKSRGGISF 394

Query: 343  LNPEGDSGTEAENDPQLTFYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSS 402
               +G SG+EA+++ QLTFYT+  RSRRRS+ G  +SPVNKT LTLI+++SC++ +VC S
Sbjct: 395  GRAKGTSGSEADDETQLTFYTEQYRSRRRSK-GLLKSPVNKTALTLIAVSSCILAMVCGS 453

Query: 403  HVNCPLVVKITLHVPEHLIADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDL 462
             ++CPL VK+TLHVPEH IADGS F++ EGS LD SDWLNPA++ L+ Q N++ PW  DL
Sbjct: 454  QMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDL 513

Query: 463  CARRLLDPCEHQCDPETGECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLV 522
            C +R  D CE  CDPETGEC C+EGY  DPVH+HLC+R++WG ++GPWPYT  +RG+DLV
Sbjct: 514  CGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLV 573

Query: 523  LGEQPSDKIFRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREEL 582
             GEQ  +KI     +LG+G+WLP+SKSFV+PP EL+INP A CKTD+ V ED  +VREE 
Sbjct: 574  TGEQAPEKIL----SLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEA 629

Query: 583  MTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSG 642
            M S+ F+++  LL SFGPVRDCS++NGGC++NF+C+SDR++DS+GCVCP  L PMKD SG
Sbjct: 630  MLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSG 689

Query: 643  CYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI 702
            CYD   G+DCSDGFNGGCEQLCLQQ  P P D T   I MFCGC+E+YKL  DG+SC ++
Sbjct: 690  CYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLML 749

Query: 703  TETCPEGSDCGESRELPMNQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQL 762
            ++ C EG  C +  +   N TLFGEM  GYNN ++ V  GQV + TFR+NNF +    QL
Sbjct: 750  SDVC-EGPKCLKP-DSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDF-PQL 806

Query: 763  PDGLVVATVPLENQCLEEISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQ 822
             DGL+V  +P+E QC   +SEP PD   LTG + + E  GYP++Q W+VRS +Y +KL+ 
Sbjct: 807  ADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLST 866

Query: 823  VAISQALSNALHSLDGATSRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLW 882
            + ++   +N L  L   +SR + ++ +  +G+HYI EA+YG E +C I +P+K+VQ++LW
Sbjct: 867  ITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLW 926

Query: 883  LEYEDISKGNSPSDESEERERDPKVLTFPEYITS--LSDSGTKHMAAGVRMECHSKGRCP 940
            L+Y+   K  +     +E +  P +      +T+  LSD     + +GV + C  KGRCP
Sbjct: 927  LQYQ---KETTELGSKKELKSMPFITYLSGLLTAQMLSDD---QLISGVEIRCEEKGRCP 980

Query: 941  SSCPLCHVTSSPDTPAEPVLLEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIE 1000
            S+C LC           PVLLE+ +  P+Y L+ +N T+   + A MSS WCSG GDVI+
Sbjct: 981  STCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVID 1040

Query: 1001 DWCRCDSTAFGADGLPTCAPLPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLR 1060
            DWCRCD +AF A+GLP C+PL QPVLRLS   EPSST+V LEW   +P IG ++ DY+L+
Sbjct: 1041 DWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQ 1100

Query: 1061 QEKVTDRMDHSKVETETVLSFVDDIISGAKSPCAMP----SQVPDKQLTTISLIIRCLEP 1116
             +KV +  D + + T   LSF DD++SG  + C        +VP  +++  S+I +CLEP
Sbjct: 1101 HKKVDEYTD-TDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVP--EVSIYSVIFKCLEP 1157

Query: 1117 DTIYMFTLWGVDNTGRRSRPSDVIVKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTA 1176
            D +Y FTL+ VD  GR S  S V ++T CP+VDD KA+EIADKIYNL+NGYTSGKEQQ A
Sbjct: 1158 DGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMA 1217

Query: 1177 YNTLLDLGSPTLHRVLYHYNQHYESFGEFTWRCEDELGPR 1216
            YNTL+++ +  L RV +HYN HYE FG+F WR EDELGPR
Sbjct: 1218 YNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPR 1257


>gi|46488915 astrotactin 2 isoform a [Homo sapiens]
          Length = 1288

 Score = 1199 bits (3101), Expect = 0.0
 Identities = 606/1236 (49%), Positives = 807/1236 (65%), Gaps = 106/1236 (8%)

Query: 16   PAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDL------------------SIMH 57
            P    ATAA   +P     C+LK++TVS LP LRE+D+                  +   
Sbjct: 46   PLLAGATAAASREPDSP--CRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAGAAAAAA 103

Query: 58   SP-------SASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQ 110
            SP       +A+E +LL  VRN+ PG + V DDL+NTELP+F LE+SG   DI LV WRQ
Sbjct: 104  SPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQ 163

Query: 111  QWLENGTLLFHIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCL 170
            QWLENGTL FH+             PT +   E  EE++ ILHISVMGG+IALLL +L  
Sbjct: 164  QWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVF 223

Query: 171  VMILYTRRRWCKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGT 230
             + LY +RRW KRRR+PQ  KSAS EA +EIHYIPSVL+G   RES R++R+Q HNS   
Sbjct: 224  TVALYAQRRWQKRRRIPQ--KSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIG 281

Query: 231  LSIRETPILDGYEYDITD----LRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDL 286
            + IRETPILD Y+ +  +      +H+ RE     ++F SQVT TLDSL           
Sbjct: 282  VPIRETPILDDYDCEEDEEPPRRANHVSRE-----DEFGSQVTHTLDSLGH--------- 327

Query: 287  TPGSDNAKLSLMNKYKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPE 346
             PG +                                       +++ + + G +F   +
Sbjct: 328  -PGEE---------------------------------------KVDFEKKGGISFGRAK 347

Query: 347  GDSGTEAENDPQLTFYTDPSRSRRRSRVGSPRSPVNKTTLTLISITSCVIGLVCSSHVNC 406
            G SG+EA+++ QLTFYT+  RSRRRS+ G  +SPVNKT LTLI+++SC++ +VC S ++C
Sbjct: 348  GTSGSEADDETQLTFYTEQYRSRRRSK-GLLKSPVNKTALTLIAVSSCILAMVCGSQMSC 406

Query: 407  PLVVKITLHVPEHLIADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARR 466
            PL VK+TLHVPEH IADGS F++ EGS LD SDWLNPA++ L+ Q N++ PW  DLC +R
Sbjct: 407  PLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQR 466

Query: 467  LLDPCEHQCDPETGECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQ 526
              D CE  CDPETGEC C+EGY  DPVH+HLC+R++WG ++GPWPYT  +RG+DLV GEQ
Sbjct: 467  TTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQ 526

Query: 527  PSDKIFRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSS 586
              +KI R T++LG+G+WLP+SKSFV+PP EL+INP A CKTD+ V ED  +VREE M S+
Sbjct: 527  APEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLST 586

Query: 587  SFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDR 646
             F+++  LL SFGPVRDCS++NGGC++NF+C+SDR++DS+GCVCP  L PMKD SGCYD 
Sbjct: 587  YFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDH 646

Query: 647  HIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETC 706
              G+DCSDGFNGGCEQLCLQQ  P P D T   I MFCGC+E+YKL  DG+SC ++++ C
Sbjct: 647  SKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVC 706

Query: 707  PEGSDCGESRELPMNQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNFARGLDQQLPDGL 766
             EG  C +  +   N TLFGEM  GYNN ++ V  GQV + TFR+NNF +    QL DGL
Sbjct: 707  -EGPKCLKP-DSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDF-PQLADGL 763

Query: 767  VVATVPLENQCLEEISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQVAIS 826
            +V  +P+E QC   +SEP PD   LTG + + E  GYP++Q W+VRS +Y +KL+ + ++
Sbjct: 764  LVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLA 823

Query: 827  QALSNALHSLDGATSRADFVALLDQFGNHYIQEAIYGFEESCSIWYPNKQVQRRLWLEYE 886
               +N L  L   +SR + ++ +  +G+HYI EA+YG E +C I +P+K+VQ++LWL+Y+
Sbjct: 824  AGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQ 883

Query: 887  DISKGNSPSDESEERERDPKVLTFPEYITS--LSDSGTKHMAAGVRMECHSKGRCPSSCP 944
               K  +     +E +  P +      +T+  LSD     + +GV + C  KGRCPS+C 
Sbjct: 884  ---KETTELGSKKELKSMPFITYLSGLLTAQMLSDD---QLISGVEIRCEEKGRCPSTCH 937

Query: 945  LCHVTSSPDTPAEPVLLEVTKAAPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCR 1004
            LC           PVLLE+ +  P+Y L+ +N T+   + A MSS WCSG GDVI+DWCR
Sbjct: 938  LCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCR 997

Query: 1005 CDSTAFGADGLPTCAPLPQPVLRLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKV 1064
            CD +AF A+GLP C+PL QPVLRLS   EPSST+V LEW   +P IG ++ DY+L+ +KV
Sbjct: 998  CDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKV 1057

Query: 1065 TDRMDHSKVETETVLSFVDDIISGAKSPCAMP----SQVPDKQLTTISLIIRCLEPDTIY 1120
             +  D + + T   LSF DD++SG  + C        +VP  +++  S+I +CLEPD +Y
Sbjct: 1058 DEYTD-TDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVP--EVSIYSVIFKCLEPDGLY 1114

Query: 1121 MFTLWGVDNTGRRSRPSDVIVKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTL 1180
             FTL+ VD  GR S  S V ++T CP+VDD KA+EIADKIYNL+NGYTSGKEQQ AYNTL
Sbjct: 1115 KFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTL 1174

Query: 1181 LDLGSPTLHRVLYHYNQHYESFGEFTWRCEDELGPR 1216
            +++ +  L RV +HYN HYE FG+F WR EDELGPR
Sbjct: 1175 MEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPR 1210


>gi|239755157 PREDICTED: similar to astrotactin 2 [Homo sapiens]
          Length = 451

 Score =  365 bits (937), Expect = e-100
 Identities = 198/393 (50%), Positives = 260/393 (66%), Gaps = 20/393 (5%)

Query: 96  ISGNTEDIPLVRWRQQWLENGTLLFHIHHQDGAPSLPGQDPTEEPQHESAEEELRILHIS 155
           +SG   DI LV WRQQWLENGTL FH+             PT +   E  EE++ ILHIS
Sbjct: 1   MSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHIS 60

Query: 156 VMGGMIALLLSILCLVMILYTRRRWCKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRE 215
           VMGG+IALLL +L   + LY +RRW KRRR+PQ  KSAS EA +EIHYIPSVL+G   RE
Sbjct: 61  VMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQ--KSASTEATHEIHYIPSVLLGPQARE 118

Query: 216 SLRNARVQGHNSSGTLSIRETPILDGYEYDITD----LRHHLQRECMNGGEDFASQVTRT 271
           S R++R+Q HNS   + IRETPILD Y+ +  +      +H+ RE     ++F SQVT T
Sbjct: 119 SFRSSRLQTHNSVIGVPIRETPILDDYDCEEDEEPPRRANHVSRE-----DEFGSQVTHT 173

Query: 272 LDSLQGCNEKSGMDL-----TPGSDNAKLSLMNKYKDNIIATSPVDSNHQQATLLSHTSS 326
           LDSL    E+  +D         +     SLM K+K++  A +P++    Q  L S TS+
Sbjct: 174 LDSLGHPGEEK-VDFEKKAAAEATQETVESLMQKFKESFRANTPIEIGQLQPPLRS-TSA 231

Query: 327 SQRKRINNKARAGSAFLNPEGDSGTEAENDPQLTFYTDPSRSRRRSRVGSPRSPVNKTTL 386
            +RKR  +K+R G +F   +G SG+EA+++ QLTFYT+  RSRRRS+ G  +SPVNKT L
Sbjct: 232 GKRKR-RSKSRGGISFGRAKGTSGSEADDETQLTFYTEQYRSRRRSK-GLLKSPVNKTAL 289

Query: 387 TLISITSCVIGLVCSSHVNCPLVVKITLHVPEHLIADGSRFILLEGSQLDASDWLNPAQV 446
           TLI+++SC++ +VC S ++CPL VK+TLHVPEH IADGS F++ EGS LD SDWLNPA++
Sbjct: 290 TLIAVSSCILAMVCGSQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKL 349

Query: 447 VLFSQQNSSGPWAMDLCARRLLDPCEHQCDPET 479
            L+ Q N++ PW  DLC +R  D CE  CDPET
Sbjct: 350 SLYYQINATSPWVRDLCGQRTTDACEQLCDPET 382


>gi|38016949 astrotactin 2 isoform d [Homo sapiens]
          Length = 395

 Score =  325 bits (834), Expect = 1e-88
 Identities = 162/314 (51%), Positives = 209/314 (66%), Gaps = 13/314 (4%)

Query: 913  YITSLSDSGTKHMAA------GVRMECHSKGRCPSSCPLCHVTSSPDTPAEPVLLEVTKA 966
            +IT LS   T  M +      GV + C  KGRCPS+C LC           PVLLE+ + 
Sbjct: 3    FITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRV 62

Query: 967  APIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAPLPQPVL 1026
             P+Y L+ +N T+   + A MSS WCSG GDVI+DWCRCD +AF A+GLP C+PL QPVL
Sbjct: 63   VPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVL 122

Query: 1027 RLSTVHEPSSTLVVLEWEHSEPPIGVQIVDYLLRQEKVTDRMDHSKVETETVLSFVDDII 1086
            RLS   EPSST+V LEW   +P IG ++ DY+L+ +KV +  D + + T   LSF DD++
Sbjct: 123  RLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTD-TDLYTGEFLSFADDLL 181

Query: 1087 SGAKSPCAMP----SQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVIVK 1142
            SG  + C        +VP  +++  S+I +CLEPD +Y FTL+ VD  GR S  S V ++
Sbjct: 182  SGLGTSCVAAGRSHGEVP--EVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLR 239

Query: 1143 TPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYESF 1202
            T CP+VDD KA+EIADKIYNL+NGYTSGKEQQ AYNTL+++ +  L RV +HYN HYE F
Sbjct: 240  TACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKF 299

Query: 1203 GEFTWRCEDELGPR 1216
            G+F WR EDELGPR
Sbjct: 300  GDFVWRSEDELGPR 313


>gi|10190748 CEGP1 protein [Homo sapiens]
          Length = 999

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 71/266 (26%), Positives = 97/266 (36%), Gaps = 48/266 (18%)

Query: 471 CEHQCDPETG--ECLCYEGYMKDPVHKHLCI-RNEWGTN-------------QGPWPYTI 514
           C+H C    G  EC C EG+     ++H CI R+E G +             + P     
Sbjct: 139 CQHTCVNVMGSYECCCKEGFFLSD-NQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVA 197

Query: 515 FQRGFDLVLGEQPSDKIFRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTD---MTV 571
            +      L +   D I   T   G G            P E + +P  K  TD      
Sbjct: 198 CECRPGFELAKNQRDCIL--TCNHGNGGCQHSCDDTADGP-ECSCHPQYKMHTDGRSCLE 254

Query: 572 MEDAVEVREELMTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTG--CV 629
            ED V    E  T+S  D  + +      +  C+ +NGGC +        K  STG  C 
Sbjct: 255 REDTVLEVTESNTTSVVDGDKRVKRRL-LMETCAVNNGGCDRTC------KDTSTGVHCS 307

Query: 630 CPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIED 689
           CP G +   D   C D    +D     NGGC+  C   +  F            CGC + 
Sbjct: 308 CPVGFTLQLDGKTCKD----IDECQTRNGGCDHFCKNIVGSFD-----------CGCKKG 352

Query: 690 YKLGVDGRSCQLITETCPEGSDCGES 715
           +KL  D +SCQ + E C     C  S
Sbjct: 353 FKLLTDEKSCQDVDE-CSLDRTCDHS 377



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 43/133 (32%)

Query: 610 GCSKNFRCISDRK---------LDST------------GCVCPSGLSPMKDSSGCYDRHI 648
           GC K F+ ++D K         LD T             C C  G + +   + C D + 
Sbjct: 348 GCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYT-LYGFTHCGDTN- 405

Query: 649 GVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSC-----QLIT 703
             +CS   NGGC+Q+C+  +  +            C C   YKL  + + C      L T
Sbjct: 406 --ECSIN-NGGCQQVCVNTVGSYE-----------CQCHPGYKLHWNKKDCVEVKGLLPT 451

Query: 704 ETCPEGS-DCGES 715
              P  S  CG+S
Sbjct: 452 SVSPRVSLHCGKS 464



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 27/112 (24%), Positives = 39/112 (34%), Gaps = 18/112 (16%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           V +C++    C  +  C       S  C C  G     +   C D     +C +  NGGC
Sbjct: 46  VDECAQGLDDCHADALC--QNTPTSYKCSCKPGYQG--EGRQCEDID---ECGNELNGGC 98

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
              CL       + P  Y     C C + + L  DG +C  + E       C
Sbjct: 99  VHDCL-------NIPGNYR----CTCFDGFMLAHDGHNCLDVDECLENNGGC 139


>gi|4507483 thrombomodulin precursor [Homo sapiens]
          Length = 575

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 17/110 (15%)

Query: 603 DCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
           DCS +NGGC      I      +  C CP+G +   D         G  C+      C  
Sbjct: 244 DCSVENGGCEHACNAIPG----APRCQCPAGAALQAD---------GRSCTASATQSCND 290

Query: 663 LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
           LC     P PD P  Y+    C C   Y+L  D   C+ + +   E S C
Sbjct: 291 LCEHFCVPNPDQPGSYS----CMCETGYRLAADQHRCEDVDDCILEPSPC 336


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 19/97 (19%)

Query: 603  DCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
            +CS +NGGCS +   +  R +    C CP GL   KD+  C    I   CS+     C Q
Sbjct: 1175 ECSLNNGGCSNHCSVVPGRGIV---CSCPEGLQLNKDNKTC---EIVDYCSNHLK--CSQ 1226

Query: 663  LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSC 699
            +C Q           +   + C C E +KL VDG SC
Sbjct: 1227 VCEQ-----------HKHTVKCSCYEGWKLDVDGESC 1252



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 18/86 (20%)

Query: 615 FRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDD 674
           ++C   R  +ST C C  G    +D   C D+    +C+    G C Q C      +   
Sbjct: 127 YKCTMVR--NSTRCYCEDGFEITEDGRSCKDQD---ECA--VYGTCSQTCRNTHGSYT-- 177

Query: 675 PTLYNILMFCGCIEDYKLGVDGRSCQ 700
                    C C+E Y +  D RSC+
Sbjct: 178 ---------CSCVEGYLMQPDNRSCK 194


>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
          Length = 988

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 23/106 (21%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTG--CVCPSGLSPMKDSSGCYDRHIGVDCSDGFNG 658
           +  C+ +NGGC +        K  +TG  C CP G +   D   C D +   +C    NG
Sbjct: 242 IETCAVNNGGCDRTC------KDTATGVRCSCPVGFTLQPDGKTCKDIN---ECLVN-NG 291

Query: 659 GCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITE 704
           GC+  C   +  F            CGC + YKL  D R+CQ I E
Sbjct: 292 GCDHFCRNTVGSFE-----------CGCRKGYKLLTDERTCQDIDE 326



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 37/146 (25%), Positives = 46/146 (31%), Gaps = 58/146 (39%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRH------------- 647
           V +C  +NGGC +    I    + S  C C SG     +   C  R              
Sbjct: 118 VDECQDNNGGCQQ----ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGC 173

Query: 648 -----------IGVDCSDGF----------------NGGCEQLCLQQMAPFPDDPTLYNI 680
                      +  DC  GF                NGGC+  C          PT    
Sbjct: 174 AHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDT----DTGPT---- 225

Query: 681 LMFCGCIEDYKLGVDGRSCQLITETC 706
              CGC + Y L  DGR+C    ETC
Sbjct: 226 ---CGCHQKYALHSDGRTC---IETC 245



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 10/73 (13%)

Query: 601 VRDCSKD--NGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNG 658
           + +C  D  NGGC     CI+     +  C C  G     D   C D     +C D  NG
Sbjct: 75  IDECENDYYNGGCVHE--CINIP--GNYRCTCFDGFMLAHDGHNCLDVD---ECQDN-NG 126

Query: 659 GCEQLCLQQMAPF 671
           GC+Q+C+  M  +
Sbjct: 127 GCQQICVNAMGSY 139



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 19/113 (16%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDC-SDGFNGG 659
           V +CS+    C  +  C +  K  S  C+C  G     +   C D     +C +D +NGG
Sbjct: 34  VDECSEGTDDCHIDAICQNTPK--SYKCLCKPGYKG--EGKQCEDID---ECENDYYNGG 86

Query: 660 CEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
           C   C+       + P  Y     C C + + L  DG +C  + E       C
Sbjct: 87  CVHECI-------NIPGNYR----CTCFDGFMLAHDGHNCLDVDECQDNNGGC 128


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 20/112 (17%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           V  C  +NGGCS      S   L    C CP G     D   C D     DC+D  +  C
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPL----CTCPRGYELDTDQRTCIDVD---DCAD--SPCC 382

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
           +Q+C        ++P  Y     CGC   Y+L  DG  C+ + E       C
Sbjct: 383 QQVCT-------NNPGGYE----CGCYAGYRLSADGCGCEDVDECASSRGGC 423



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 29/142 (20%)

Query: 568 DMTVMEDAVEVREELMTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTG 627
           D+   E+  E+R E   +  F  L+   DSFG   DCS     C     C+    L   G
Sbjct: 489 DVGADEEEAELRGEHTLTEKFVCLD---DSFG--HDCSLTCDDCRNGGTCL----LGLDG 539

Query: 628 CVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCI 687
           C CP G + +  +  C     G +CS  F+  C+           +  T  ++   C C 
Sbjct: 540 CDCPEGWTGLICNETCPPDTFGKNCS--FSCSCQ-----------NGGTCDSVTGACRC- 585

Query: 688 EDYKLGVDGRSCQLITETCPEG 709
                GV G +C+   + CP+G
Sbjct: 586 ---PPGVSGTNCE---DGCPKG 601



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 18/112 (16%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           +  C+  NGGC  +  C+    +    C C  G    +D   C  R     C++  NG C
Sbjct: 203 INSCALGNGGCQHH--CVQ-LTITRHRCQCRPGFQLQEDGRHCVRRS---PCANR-NGSC 255

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
              C            +   L  C C   Y+L  DG++C+ + E     + C
Sbjct: 256 MHRC-----------QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQC 296



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 30/99 (30%), Positives = 34/99 (34%), Gaps = 19/99 (19%)

Query: 604 CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQL 663
           C+  NG C    RC   R L    C C  G     D   C D     +C+ G    C   
Sbjct: 248 CANRNGSCMH--RCQVVRGL--ARCECHVGYQLAADGKACEDVD---ECAAGL-AQCAHG 299

Query: 664 CLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI 702
           CL     F            C C   Y+LG DGR C  I
Sbjct: 300 CLNTQGSFK-----------CVCHAGYELGADGRQCYRI 327



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 37/133 (27%), Positives = 48/133 (36%), Gaps = 40/133 (30%)

Query: 610  GCSKNFRCISDRKLDS-TG-CVCPSGLSPMKDSSGCYDRHIGVDCSD------------- 654
            GC  +  C++    D  TG C+CP+G +  K  S C     G  C+              
Sbjct: 1084 GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHV 1143

Query: 655  --------GFNG-GCEQLC--------LQQMAPFP-DDPTLYNILMFCGCIEDYKLGVDG 696
                    GF G GCEQ C          QM   P ++P  +     C C   Y     G
Sbjct: 1144 TGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGY----HG 1199

Query: 697  RSCQLITETCPEG 709
             SCQ   + CP G
Sbjct: 1200 PSCQ---QRCPPG 1209



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 4/36 (11%)

Query: 456 GPWAMDLCARRLLDPCEH--QCDPETGECLCYEGYM 489
           G W +    + +   C+H  +CDPETG CLC  G++
Sbjct: 776 GRWGLG--CQEICPACQHAARCDPETGACLCLPGFV 809



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/77 (29%), Positives = 26/77 (33%), Gaps = 15/77 (19%)

Query: 628 CVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCI 687
           C C +G     D  GC D    VD      GGCE  C      F            C C 
Sbjct: 395 CGCYAGYRLSADGCGCED----VDECASSRGGCEHHCTNLAGSFQ-----------CSCE 439

Query: 688 EDYKLGVDGRSCQLITE 704
             Y+L  D R C  + E
Sbjct: 440 AGYRLHEDRRGCSPLEE 456



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 37/125 (29%), Positives = 43/125 (34%), Gaps = 41/125 (32%)

Query: 604 CSKDNGG--CSKNFRCISDRKLDST--GCVCPSGLSPMKDSSGC----YDRHIGVDCSDG 655
           C  D  G  CS +  C +    DS    C CP G+S      GC    Y +H    C+  
Sbjct: 555 CPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCA 614

Query: 656 FNGGCEQL---CLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPE---G 709
             G C +L   CL        DP LY                 GR C L   TCP    G
Sbjct: 615 NRGRCHRLYGACL-------CDPGLY-----------------GRFCHL---TCPPWAFG 647

Query: 710 SDCGE 714
             C E
Sbjct: 648 PGCSE 652


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 20/121 (16%)

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
            + +CS  +  C +N +C++   + +  C C  G     D  GC D    +D     NGGC
Sbjct: 1201 INECSLSDNLC-RNGKCVN--MIGTYQCSCNPGYQATPDRQGCTD----IDECMIMNGGC 1253

Query: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI--TETCPEGSDCGESREL 718
            +  C      +            C C E Y L  DGRSC  I   E  P+  D G+   +
Sbjct: 1254 DTQCTNSEGSYE-----------CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNI 1302

Query: 719  P 719
            P
Sbjct: 1303 P 1303



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 11/90 (12%)

Query: 610 GCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMA 669
           G   N  CI+     S  C CP GL+   D   C D H+   C  G   G   +C++   
Sbjct: 666 GICMNGHCINSE--GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG---VCVR--- 717

Query: 670 PFPDDPTLYNILMFCGCIEDYKLGVDGRSC 699
           PFP   T       C    DY  G   + C
Sbjct: 718 PFPGAVTKSEC---CCANPDYGFGEPCQPC 744



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 628 CVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
           CVCP G     D S C D+  G+  S   NG C Q
Sbjct: 343 CVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQ 377



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 12/68 (17%)

Query: 599  GPVRDCSKDNGGCSKN-----FRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCS 653
            GP+ +C +D   C++N     FRC++     S  C CP G +  +D   C D     +C+
Sbjct: 2246 GPMMNC-EDINECAQNPLLCAFRCMNT--FGSYECTCPIGYALREDQKMCKDLD---ECA 2299

Query: 654  DGFNGGCE 661
            +G +  CE
Sbjct: 2300 EGLH-DCE 2306


>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
          Length = 993

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 19/104 (18%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           +  C+ +NGGC       +        C CP G     D   C D    +D     NGGC
Sbjct: 237 IETCAVNNGGCDSKCHDAAT----GVHCTCPVGFMLQPDRKTCKD----IDECRLNNGGC 288

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITE 704
           + +C   +  F            C C + YKL ++ R+CQ I E
Sbjct: 289 DHICRNTVGSFE-----------CSCKKGYKLLINERNCQDIDE 321



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 23/113 (20%)

Query: 601 VRDCSK-DNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGG 659
           V +C + DN GC  +  C++     +  C C  G     D   C D     +C++G NGG
Sbjct: 71  VDECEREDNAGCVHD--CVNIP--GNYRCTCYDGFHLAHDGHNCLDVD---ECAEG-NGG 122

Query: 660 CEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
           C+Q C+  M  +            C C E + L  +  +C    +   EG +C
Sbjct: 123 CQQSCVNMMGSYE-----------CHCREGFFLSDNQHTC---IQRPEEGMNC 161



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 29/104 (27%), Positives = 39/104 (37%), Gaps = 23/104 (22%)

Query: 603 DCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
           +C   N GC+   R   +       C C  G    K+   C      + C+ G NGGC+ 
Sbjct: 160 NCMNKNHGCAHICR---ETPKGGIACECRPGFELTKNQRDCK-----LTCNYG-NGGCQH 210

Query: 663 LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETC 706
            C         D T       CGC   + L  DG++C    ETC
Sbjct: 211 TC---------DDTEQGPR--CGCHIKFVLHTDGKTC---IETC 240



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 19/110 (17%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           V +C +    C  +  C +  +  S  C+C SG +   D   C D     +C    N GC
Sbjct: 30  VDECVEGTDNCHIDAICQNTPR--SYKCICKSGYTG--DGKHCKDVD---ECEREDNAGC 82

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGS 710
              C+       + P  Y     C C + + L  DG +C L  + C EG+
Sbjct: 83  VHDCV-------NIPGNYR----CTCYDGFHLAHDGHNC-LDVDECAEGN 120


>gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo
           sapiens]
          Length = 678

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 15/89 (16%)

Query: 651 DCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGS 710
           +CS   NGGC Q+C  +   F            C C   ++L  DGR+CQ I E C +  
Sbjct: 159 ECSQE-NGGCLQICHNKPGSF-----------HCSCHSGFELSSDGRTCQDIDE-CADSE 205

Query: 711 DCGESR--ELPMNQTLFGEMFFGYNNHSK 737
            CGE+R   LP + +   +  F Y++  K
Sbjct: 206 ACGEARCKNLPGSYSCLCDEGFAYSSQEK 234



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 20/109 (18%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           V +CS++NGGC +    I   K  S  C C SG     D   C D     D        C
Sbjct: 157 VNECSQENGGCLQ----ICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARC 212

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEG 709
           + L           P  Y+    C C E +      ++C+ + E C +G
Sbjct: 213 KNL-----------PGSYS----CLCDEGFAYSSQEKACRDVDE-CLQG 245


>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
           sapiens]
          Length = 1207

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 19/92 (20%)

Query: 611 CSKNF-RCISDRKLDSTG--CVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQ 667
           C +N   C  D  L S G  C CP G    +D   C        CS   NGGC QLC+  
Sbjct: 401 CPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSG------CSSPDNGGCSQLCV-- 452

Query: 668 MAPFPDDPTLYNILMFCGCIEDYKLGVDGRSC 699
               P  P  +     C C   Y L +D +SC
Sbjct: 453 ----PLSPVSWE----CDCFPGYDLQLDEKSC 476



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 20/110 (18%)

Query: 604 CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQL 663
           C    G CS     +  + L S  C+C  G +  +D   C D +   +C+  +N GC   
Sbjct: 318 CKLRKGNCSST---VCGQDLQSHLCMCAEGYALSRDRKYCEDVN---ECA-FWNHGCTLG 370

Query: 664 CLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEG-SDC 712
           C        + P  Y    +C C   + L  DG+ C  +  +CP   S+C
Sbjct: 371 C-------KNTPGSY----YCTCPVGFVLLPDGKRCHQLV-SCPRNVSEC 408


>gi|126012562 low density lipoprotein-related protein 1 [Homo
           sapiens]
          Length = 4544

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/104 (30%), Positives = 38/104 (36%), Gaps = 21/104 (20%)

Query: 604 CSKDNGGCSK---NFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
           C +  G CS+      C+    LD   C C S      D   C D     +CS    G C
Sbjct: 108 CRELQGNCSRLGCQHHCVPT--LDGPTCYCNSSFQLQADGKTCKDFD---ECS--VYGTC 160

Query: 661 EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITE 704
            QLC      F            CGC+E Y L  D RSC+   E
Sbjct: 161 SQLCTNTDGSF-----------ICGCVEGYLLQPDNRSCKAKNE 193



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 19/97 (19%)

Query: 604  CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQL 663
            CS +NGGCS N    S    +   C CP G+    D+  C    I   C+      C Q 
Sbjct: 1185 CSLNNGGCSHN---CSVAPGEGIVCSCPLGMELGPDNHTC---QIQSYCAKHLK--CSQK 1236

Query: 664  CLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQ 700
            C Q               + C C E + L  DG SC+
Sbjct: 1237 CDQN-----------KFSVKCSCYEGWVLEPDGESCR 1262



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 33/138 (23%), Positives = 48/138 (34%), Gaps = 34/138 (24%)

Query: 600 PVRDCSKDNGGC-SKNFRCISDRKL----DSTGCVCPSGLSP--MKDSSGCYDRHIGV-- 650
           P +   +D   C SK +RC  +R      D    +CP   +     +   C    + V  
Sbjct: 29  PKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPM 88

Query: 651 --------DCSDG---------FNGGCEQL-CLQQMAPFPDDPTLYNILMFCGCIEDYKL 692
                   DC DG           G C +L C     P  D PT Y       C   ++L
Sbjct: 89  SRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCY-------CNSSFQL 141

Query: 693 GVDGRSCQLITETCPEGS 710
             DG++C+   E    G+
Sbjct: 142 QADGKTCKDFDECSVYGT 159



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 42/169 (24%), Positives = 64/169 (37%), Gaps = 32/169 (18%)

Query: 538  LGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDS 597
            +G  +  P SK + I      IN   +C  D + +E    +R +L  +++   L ++ D 
Sbjct: 1745 VGLAIDFPESKLYWISSGNHTIN---RCNLDGSGLEVIDAMRSQLGKATA---LAIMGDK 1798

Query: 598  FGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVD------ 651
                   S+  G CSK          D +G V     + +      YD  I +D      
Sbjct: 1799 LWWADQVSEKMGTCSK---------ADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNP 1849

Query: 652  CSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQ 700
            CS   NG C QLCL      P   T  +    C C   Y L    ++C+
Sbjct: 1850 CSVN-NGDCSQLCL------PTSETTRS----CMCTAGYSLRSGQQACE 1887


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 9/60 (15%)

Query: 604  CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVD-CSDGFNGGCEQ 662
            C +DNGGC+K  RC   +K     C C  G     D   C +    +D C+DG NGGC +
Sbjct: 2086 CKQDNGGCAKVARC--SQKGTKVSCSCQKGYK--GDGHSCTE----IDPCADGLNGGCHE 2137



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 58/253 (22%), Positives = 88/253 (34%), Gaps = 54/253 (21%)

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTG---CVCPSGLS----PMKDSSGCYDRHIGVDCS 653
            +  C   NGGCS    C    K  + G   C C +G +       + + C + H G D  
Sbjct: 1472 INACEISNGGCSAKADC----KRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCD-- 1525

Query: 654  DGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCG 713
               N  C Q    Q A              C C+  Y    DG+ C LI     +   C 
Sbjct: 1526 --KNAECTQTGPNQAA--------------CNCLPAYT--GDGKVCTLINVCLTKNGGCS 1567

Query: 714  ESRELPMNQTLFGEMFFGYNNHSKEVAAGQVLKGTFRQNNF-ARG-LDQQLPDGLVVAT- 770
            E               F   NH+ +V      K  +  + F  RG + Q+LP     +  
Sbjct: 1568 E---------------FAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPKTSQY 1612

Query: 771  -VPLENQCLEEISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHI-KLNQVAISQA 828
               L+   ++++  P P   F      F E +    ++ W    +M  + + + VA  Q 
Sbjct: 1613 FFQLQEHFVKDLVGPGPFTVFAPLSAAFDEEAR---VKDWDKYGLMPQVLRYHVVACHQL 1669

Query: 829  LSNALHSLDGATS 841
            L   L  +  ATS
Sbjct: 1670 LLENLKLISNATS 1682



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 30/112 (26%)

Query: 609 GGCSKNFRCISDRKLDSTGCVCPSGLSP------------MKDSSGCYDR----HIG--- 649
           GGCS+N  CI       T CVC  G +             +  + GC+D     ++G   
Sbjct: 877 GGCSRNAECIKTGTGTHT-CVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQ 935

Query: 650 --VDCSDGFNGG---CEQL--CLQQMA---PFPDDPTLYNILMFCGCIEDYK 691
              +C  GF G    CE +  CL+Q     P     +  + +  C C E Y+
Sbjct: 936 NECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE 987


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 20/98 (20%)

Query: 604  CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQL 663
            CS  NGGC+    C+ +       C+CP G     DS  C D    +D  D   G C Q 
Sbjct: 1353 CSDFNGGCTHE--CVQEPF--GAKCLCPLGFLLANDSKTCED----IDECD-ILGSCSQH 1403

Query: 664  CLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQL 701
            C      F            C C   Y L  DGR+C++
Sbjct: 1404 CYNMRGSFR-----------CSCDTGYMLESDGRTCKV 1430



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 29/96 (30%), Positives = 35/96 (36%), Gaps = 22/96 (22%)

Query: 614  NFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGV-DCSDGFNGGCEQLCLQQMAPFP 672
            N RCI   KL    C          D  GC     G+ +C D    GC+  C   +  F 
Sbjct: 3084 NGRCIEMMKL----CNHLDDCLDNSDEKGC-----GINECHDPSISGCDHNCTDTLTSF- 3133

Query: 673  DDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPE 708
                      +C C   YKL  D R+C  I E C E
Sbjct: 3134 ----------YCSCRPGYKLMSDKRTCVDIDE-CTE 3158



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 11/48 (22%)

Query: 652  CSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSC 699
            CS+  N  C+Q+CL    P P        L  C C   +KL  D RSC
Sbjct: 2022 CSNNMNA-CQQICL----PVPGG------LFSCACATGFKLNPDNRSC 2058


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 20/121 (16%)

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
            + +CS  +G C    +C++   + +  C C +G     D  GC D +   +C    NGGC
Sbjct: 1114 IDECSLSDGLCPHG-QCVN--VIGAFQCSCHAGFQSTPDRQGCVDIN---ECRVQ-NGGC 1166

Query: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI--TETCPEGSDCGESREL 718
            +  C+     +            C C + Y L  DGR+C  +   E  P   D G    +
Sbjct: 1167 DVHCINTEGSYR-----------CSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNM 1215

Query: 719  P 719
            P
Sbjct: 1216 P 1216



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 28/142 (19%)

Query: 596  DSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRH---IGVDC 652
            DS   V +C+++ G C+      +D    S  C CP G S       C D     +G  C
Sbjct: 2080 DSREDVNECAENPGVCTNGVCVNTD---GSFRCECPFGYSLDFTGINCVDTDECSVGHPC 2136

Query: 653  SDG----FNGGCEQLCLQQMAPFP-------DDPTLYNILM-----------FCGCIEDY 690
              G      GG E  C     P         D+ +L  +L             C C   Y
Sbjct: 2137 GQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGY 2196

Query: 691  KLGVDGRSCQLITETCPEGSDC 712
             L  DG  C+ + E      DC
Sbjct: 2197 TLREDGAMCRDVDECADGQQDC 2218



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 17/96 (17%)

Query: 617  CISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPT 676
            CI+   L S  C C +G +P   ++ C D     +CS      C  LC      F     
Sbjct: 2379 CINS--LGSFRCHCQAGYTPDATATTCLDMD---ECSQ-VPKPCTFLCKNTKGSF----- 2427

Query: 677  LYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
                   C C   Y L  DGR+C+ + E      +C
Sbjct: 2428 ------LCSCPRGYLLEEDGRTCKDLDECTSRQHNC 2457


>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
          Length = 1200

 Score = 38.5 bits (88), Expect = 0.039
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 29/130 (22%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMK--------DSSGCYDRHIGVDC 652
           V DC    G C     C     ++   CVCP G              SS C+   +  D 
Sbjct: 424 VNDC---RGQCQHGGTCKD--LVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 478

Query: 653 SDGFNGGCEQ-----LC-----LQQMAPFPDDPTLYNIL--MFCGCIEDYKLGVDGRSCQ 700
           +DGF+  C Q     LC     L + +P  +    YN+    +C C +D+     G++C 
Sbjct: 479 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF----GGKNCS 534

Query: 701 LITETCPEGS 710
           +  E CP G+
Sbjct: 535 VPREPCPGGA 544


>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
          Length = 1238

 Score = 38.5 bits (88), Expect = 0.039
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 29/130 (22%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMK--------DSSGCYDRHIGVDC 652
           V DC    G C     C     ++   CVCP G              SS C+   +  D 
Sbjct: 462 VNDC---RGQCQHGGTCKD--LVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 516

Query: 653 SDGFNGGCEQ-----LC-----LQQMAPFPDDPTLYNIL--MFCGCIEDYKLGVDGRSCQ 700
           +DGF+  C Q     LC     L + +P  +    YN+    +C C +D+     G++C 
Sbjct: 517 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF----GGKNCS 572

Query: 701 LITETCPEGS 710
           +  E CP G+
Sbjct: 573 VPREPCPGGA 582


>gi|24430141 fibrillin 1 precursor [Homo sapiens]
          Length = 2871

 Score = 37.7 bits (86), Expect = 0.067
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 18/112 (16%)

Query: 601  VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGC 660
            + +C   +  C +N  C++DR   S  C+C +G +P    + C D +   +C+      C
Sbjct: 2403 IDECKVIHDVC-RNGECVNDR--GSYHCICKTGYTPDITGTSCVDLN---ECNQAPKP-C 2455

Query: 661  EQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
              +C      +            C C + Y L  DGRSC+ + E   +  +C
Sbjct: 2456 NFICKNTEGSYQ-----------CSCPKGYILQEDGRSCKDLDECATKQHNC 2496



 Score = 35.0 bits (79), Expect = 0.43
 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 18/109 (16%)

Query: 608 NGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQ 667
           NG    N RCI+     S  CVC +G    +D   C D     +CS         +CL  
Sbjct: 537 NGRICNNGRCINTD--GSFHCVCNAGFHVTRDGKNCEDMD---ECS------IRNMCLNG 585

Query: 668 MAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESR 716
           M    D          C C   ++L  DGR C+ I E C     C   R
Sbjct: 586 MCINEDGS------FKCICKPGFQLASDGRYCKDINE-CETPGICMNGR 627



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 19/108 (17%)

Query: 614  NFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPD 673
            N RC++   +    C C  G     D   C D    +D     NGGCE  C      +  
Sbjct: 1168 NGRCVN--LIGKYQCACNPGYHSTPDRLFCVD----IDECSIMNGGCETFCTNSEGSYE- 1220

Query: 674  DPTLYNILMFCGCIEDYKLGVDGRSCQLI--TETCPEGSDCGESRELP 719
                      C C   + L  D RSC  I   E  P   D G+   +P
Sbjct: 1221 ----------CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIP 1258



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 28/116 (24%), Positives = 42/116 (36%), Gaps = 27/116 (23%)

Query: 601  VRDCSKD---NGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFN 657
            + +C +D   NG C           + S  C C  G   +  ++ C D     +C+ G  
Sbjct: 1892 INECERDACGNGTCRNT--------IGSFNCRCNHGFI-LSHNNDCIDVD---ECASGNG 1939

Query: 658  GGCEQ-LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEGSDC 712
              C    C+  +  F            C C E Y++  DGR+C  I E   E   C
Sbjct: 1940 NLCRNGQCINTVGSFQ-----------CQCNEGYEVAPDGRTCVDINECLLEPRKC 1984


>gi|46249414 latent transforming growth factor beta binding protein 1
            isoform LTBP-1L [Homo sapiens]
          Length = 1722

 Score = 37.7 bits (86), Expect = 0.067
 Identities = 51/244 (20%), Positives = 80/244 (32%), Gaps = 64/244 (26%)

Query: 482  CLCYEGYMKDPVHKH-----------LCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDK 530
            C C++GY + P HKH           LC+  +    +G +  T  Q G+ L   +   + 
Sbjct: 1063 CSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQ-GYQLSAAKDQCED 1121

Query: 531  I--FRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSF 588
            I   +  +    G       SF             +C  D                    
Sbjct: 1122 IDECQHRHLCAHGQCRNTEGSF-------------QCVCDQGYRASG------------- 1155

Query: 589  DSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHI 648
                 L D    + +C +D   C +   CI+     S  C CP G   + D+  C D + 
Sbjct: 1156 -----LGDHCEDINECLEDKSVCQRG-DCINTA--GSYDCTCPDGFQ-LDDNKTCQDIN- 1205

Query: 649  GVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPE 708
              +C      G +  CL     F            C C + + +  DGR+C+ I E C  
Sbjct: 1206 --ECEHPGLCGPQGECLNTEGSF-----------HCVCQQGFSISADGRTCEDIDE-CVN 1251

Query: 709  GSDC 712
             + C
Sbjct: 1252 NTVC 1255


>gi|46249412 latent transforming growth factor beta binding protein
           1 isoform LTBP-1S [Homo sapiens]
          Length = 1396

 Score = 37.7 bits (86), Expect = 0.067
 Identities = 51/244 (20%), Positives = 80/244 (32%), Gaps = 64/244 (26%)

Query: 482 CLCYEGYMKDPVHKH-----------LCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDK 530
           C C++GY + P HKH           LC+  +    +G +  T  Q G+ L   +   + 
Sbjct: 737 CSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQ-GYQLSAAKDQCED 795

Query: 531 I--FRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSF 588
           I   +  +    G       SF             +C  D                    
Sbjct: 796 IDECQHRHLCAHGQCRNTEGSF-------------QCVCDQGYRASG------------- 829

Query: 589 DSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHI 648
                L D    + +C +D   C +   CI+     S  C CP G   + D+  C D + 
Sbjct: 830 -----LGDHCEDINECLEDKSVCQRG-DCINTA--GSYDCTCPDGFQ-LDDNKTCQDIN- 879

Query: 649 GVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPE 708
             +C      G +  CL     F            C C + + +  DGR+C+ I E C  
Sbjct: 880 --ECEHPGLCGPQGECLNTEGSF-----------HCVCQQGFSISADGRTCEDIDE-CVN 925

Query: 709 GSDC 712
            + C
Sbjct: 926 NTVC 929


>gi|157384998 low density lipoprotein receptor-related protein 4
           [Homo sapiens]
          Length = 1905

 Score = 37.7 bits (86), Expect = 0.067
 Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 18/108 (16%)

Query: 604 CSKDNGGCSKNFRCISDRKLDS--TGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCE 661
           C+ D   C  N RCI  RKL +    C   S  SP ++   C  R    +C+   NGGC 
Sbjct: 312 CALDQFLCW-NGRCIGQRKLCNGVNDCGDNSDESPQQN---CRPRTGEENCNVN-NGGCA 366

Query: 662 QLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLITETCPEG 709
           Q C            +    + C C   Y+L  DG +CQ + E   EG
Sbjct: 367 QKC-----------QMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEG 403



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 20/100 (20%)

Query: 603 DCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
           +C+ +NGGC++  + +      +  C C +G    +D   C D +   +C++   G C Q
Sbjct: 357 NCNVNNGGCAQKCQMVRG----AVQCTCHTGYRLTEDGHTCQDVN---ECAE--EGYCSQ 407

Query: 663 LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQLI 702
            C      F            C C   Y+L  D RSC+ +
Sbjct: 408 GCTNSEGAFQ-----------CWCETGYELRPDRRSCKAL 436



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 2/40 (5%)

Query: 604  CSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGC 643
            C+ +NGGCS    C+         C CP+G++ + D   C
Sbjct: 1006 CAMENGGCSH--LCLRSPNPSGFSCTCPTGINLLSDGKTC 1043


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 43/197 (21%), Positives = 73/197 (37%), Gaps = 29/197 (14%)

Query: 560 NPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCIS 619
           N   +C  +    E+A EV E    ++ F    V  D          ++  C     C  
Sbjct: 59  NLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQC--------ESNPCLNGGSCKD 110

Query: 620 DRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYN 679
           D  ++S  C CP G     +   C    + V C+   NG CEQ C              +
Sbjct: 111 D--INSYECWCPFGF----EGKNC---ELDVTCNIK-NGRCEQFCKNSA----------D 150

Query: 680 ILMFCGCIEDYKLGVDGRSCQLITETCPEGSDCGESRELPMNQTLFGEMFFGYNNHSKEV 739
             + C C E Y+L  + +SC+             ++ +L   +T+F ++ +  N+   E 
Sbjct: 151 NKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDY-VNSTEAET 209

Query: 740 AAGQVLKGTFRQNNFAR 756
               + + T   N+F R
Sbjct: 210 ILDNITQSTQSFNDFTR 226


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 16/77 (20%)

Query: 651 DCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQ-----LITET 705
           +C+    GGCEQ CL  +  +            C C   Y+LG D RSC+     L+T+ 
Sbjct: 577 ECAKPDRGGCEQRCLNTLGSYQ-----------CACEPGYELGPDRRSCEAACGGLLTKL 625

Query: 706 CPEGSDCGESRELPMNQ 722
               +  G  +E P N+
Sbjct: 626 NGTITTPGWPKEYPPNK 642


>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
          Length = 757

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 11/53 (20%)

Query: 648 IGVDCSDGFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQ 700
           +G  CS   NGGCE  C++++             + C C E ++L  DGRSC+
Sbjct: 231 LGTGCSPD-NGGCEHECVEEVDGH----------VSCRCTEGFRLAADGRSCE 272



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/132 (25%), Positives = 44/132 (33%), Gaps = 52/132 (39%)

Query: 604 CSKDNGGCSK----------NFRCISDRKLDSTG-------------------------C 628
           CS DNGGC            + RC    +L + G                         C
Sbjct: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294

Query: 629 VCPSGLSPMKDSSGCYDRHIGVDCSD-GFNGGCEQLCLQQMAPFPDDPTLYNILMFCGCI 687
            C  G  P +D     D H  VD  +    G C+Q+C+  +  F            C C 
Sbjct: 295 HCRLGFRPAED-----DPHRCVDTDECQIAGVCQQMCVNYVGGFE-----------CYCS 338

Query: 688 EDYKLGVDGRSC 699
           E ++L  DG SC
Sbjct: 339 EGHELEADGISC 350


>gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
          Length = 545

 Score = 36.2 bits (82), Expect = 0.20
 Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 19/99 (19%)

Query: 603 DCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQ 662
           +C ++NGGCS+   C++ +  +S  C C  G     D   C D    V+     NGGC  
Sbjct: 185 ECEQNNGGCSE--ICVNLK--NSYRCECGVGRVLRSDGKTCED----VEGCHNNNGGCSH 236

Query: 663 LCLQQMAPFPDDPTLYNILMFCGCIEDYKLGVDGRSCQL 701
            CL     +            C C     L  D  +CQ+
Sbjct: 237 SCLGSEKGYQ-----------CECPRGLVLSEDNHTCQV 264



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 4/43 (9%)

Query: 601 VRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGC 643
           V  C  +NGGCS +  C+   K     C CP GL   +D+  C
Sbjct: 224 VEGCHNNNGGCSHS--CLGSEK--GYQCECPRGLVLSEDNHTC 262


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,416,443
Number of Sequences: 37866
Number of extensions: 2530219
Number of successful extensions: 7229
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 6738
Number of HSP's gapped (non-prelim): 505
length of query: 1216
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1102
effective length of database: 13,930,794
effective search space: 15351734988
effective search space used: 15351734988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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