Search of human proteins with 46397373

Search of human proteins with 46397373

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46397373 leucine rich repeat containing 20 isoform 2 [Homo
sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46397373 leucine rich repeat containing 20 isoform 2 [Homo sa...   261   2e-70
gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo sa...   237   2e-63
gi|8922644 leucine rich repeat containing 20 isoform 3 [Homo sap...   143   4e-35
gi|21361633 leucine rich repeat containing 40 [Homo sapiens]           55   2e-08
gi|37221175 PH domain and leucine rich repeat protein phosphatas...    55   2e-08
gi|28872863 CCR4-NOT transcription complex, subunit 6 [Homo sapi...    54   5e-08
gi|11321571 slit homolog 3 [Homo sapiens]                              53   6e-08
gi|194394161 leucine rich repeat containing 57 [Homo sapiens]          53   6e-08
gi|115583679 CCR4-NOT transcription complex, subunit 6-like [Hom...    52   1e-07
gi|122937315 leucine-rich repeats and IQ motif containing 4 [Hom...    52   1e-07
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]           52   2e-07
gi|110825984 malignant fibrous histiocytoma amplified sequence 1...    51   2e-07
gi|14249428 leucine-rich repeats and calponin homology (CH) doma...    51   2e-07
gi|238908508 leucine-rich repeat and death domain-containing pro...    50   4e-07
gi|40254924 leucine rich repeat containing 59 [Homo sapiens]           50   4e-07
gi|157694513 leucine-rich repeat-containing G protein-coupled re...    50   4e-07
gi|21389431 leucine rich repeat containing 39 [Homo sapiens]           50   5e-07
gi|167466264 leucine rich repeat containing 18 [Homo sapiens]          49   2e-06
gi|41582239 immunoglobulin superfamily containing leucine-rich r...    48   2e-06
gi|5031809 immunoglobulin superfamily containing leucine-rich re...    48   2e-06
gi|4504379 leucine-rich repeat-containing G protein-coupled rece...    48   3e-06
gi|24308207 leucine rich repeat containing 47 [Homo sapiens]           48   3e-06
gi|153792305 leucine rich repeat containing 58 [Homo sapiens]          48   3e-06
gi|61742786 leucine rich repeat and death domain containing prot...    47   4e-06
gi|61742784 leucine rich repeat and death domain containing prot...    47   4e-06
gi|61742782 leucine rich repeat and death domain containing prot...    47   4e-06
gi|53729363 leucine rich repeat and sterile alpha motif containi...    47   4e-06
gi|53729361 leucine rich repeat and sterile alpha motif containi...    47   4e-06
gi|53729359 leucine rich repeat and sterile alpha motif containi...    47   4e-06
gi|63003903 leucine rich repeat containing 10 [Homo sapiens]           47   5e-06

>gi|46397373 leucine rich repeat containing 20 isoform 2 [Homo
           sapiens]
          Length = 134

 Score =  261 bits (666), Expect = 2e-70
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MLKKMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQ 60
           MLKKMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQ
Sbjct: 1   MLKKMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQ 60

Query: 61  DFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKF 120
           DFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKF
Sbjct: 61  DFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKF 120

Query: 121 DMLMSPEGARAPLP 134
           DMLMSPEGARAPLP
Sbjct: 121 DMLMSPEGARAPLP 134


>gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo
           sapiens]
          Length = 184

 Score =  237 bits (605), Expect = 2e-63
 Identities = 134/184 (72%), Positives = 134/184 (72%), Gaps = 50/184 (27%)

Query: 1   MLKKMGEAVARVARKVNETVESGSDTL--------------------------------- 27
           MLKKMGEAVARVARKVNETVESGSDTL                                 
Sbjct: 1   MLKKMGEAVARVARKVNETVESGSDTLDLAECKLVSFPIGIYKVLRNVSGQIHLITLANN 60

Query: 28  -----------------ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALP 70
                            ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALP
Sbjct: 61  ELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALP 120

Query: 71  ALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR 130
           ALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR
Sbjct: 121 ALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR 180

Query: 131 APLP 134
           APLP
Sbjct: 181 APLP 184


>gi|8922644 leucine rich repeat containing 20 isoform 3 [Homo
           sapiens]
          Length = 128

 Score =  143 bits (361), Expect = 4e-35
 Identities = 87/140 (62%), Positives = 99/140 (70%), Gaps = 18/140 (12%)

Query: 1   MLKKMGEAVARVARKVNETVESGSDTLELHLEGNF------LHRLPSEVSALQHLKAIDL 54
           MLKKMGEAVARVARKVNETVESGSDTL+L  E         ++++   VS   HL  I L
Sbjct: 1   MLKKMGEAVARVARKVNETVESGSDTLDL-AECKLVSFPIGIYKVLRNVSGQIHL--ITL 57

Query: 55  SRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIA 114
           + N+ +    +              +++ DVPVEKLAAMPALRSINLRFNPLNAEVRVIA
Sbjct: 58  ANNELKSLTSKFMTT---------FSQLRDVPVEKLAAMPALRSINLRFNPLNAEVRVIA 108

Query: 115 PPLIKFDMLMSPEGARAPLP 134
           PPLIKFDMLMSPEGARAPLP
Sbjct: 109 PPLIKFDMLMSPEGARAPLP 128


>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
          Length = 602

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 30/78 (38%), Positives = 47/78 (60%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  NFL+ LP E+ +L  L+ I+LS N+F+  PE L  +  LETI +  N++  V  +
Sbjct: 477 LDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ 536

Query: 89  KLAAMPALRSINLRFNPL 106
           K+  M  L +++L+ N L
Sbjct: 537 KMKMMENLTTLDLQNNDL 554



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L +  N L  LPS +  L++L+ +++S N+ +  PE++T L  L+ + L+ NE+  +  E
Sbjct: 110 LDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCIS-E 168

Query: 89  KLAAMPALRSINLRFNPL 106
               +  L  ++L  N L
Sbjct: 169 GFEQLSNLEDLDLSNNHL 186



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L+ N L  +      L +L+ +DLS N     P   ++L +L  +NL  NE+  +P E
Sbjct: 156 LYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAE 215

Query: 89  KLAAMPALRSINLRFNPL 106
            +  M  L+ ++   N L
Sbjct: 216 -INRMKRLKHLDCNSNLL 232



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 21/80 (26%), Positives = 43/80 (53%), Gaps = 1/80 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L    N L  +P E++ ++ L+ + L RN+ +  PE   +   L+ +++ EN+I  +  E
Sbjct: 225 LDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEMLEAE 283

Query: 89  KLAAMPALRSINLRFNPLNA 108
            L  + ++  ++LR N L +
Sbjct: 284 HLKHLNSILVLDLRDNKLKS 303



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 17/94 (18%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAI---DLSRNQFQDFPEQLTALPALETINLEENEIVD 84
           ELH+  N +  L +E   L+HL +I   DL  N+ +  P+++  L +LE ++L  N+I  
Sbjct: 269 ELHVGENQIEMLEAE--HLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISS 326

Query: 85  VPVEKLAAMPALRSINLRF-----NPLNAEVRVI 113
           +P        +L +++L+F     NPL    R I
Sbjct: 327 LPY-------SLGNLHLKFLALEGNPLRTIRREI 353



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 9   VARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTA 68
           +  + +++ E  E  SD   + L  N L  +  E+  LQ L  +DL  N     PE++ +
Sbjct: 437 LCEIPKRMVELKEMVSD---VDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMES 493

Query: 69  LPALETINLEENEIVDVP 86
           L  L+TINL  N    +P
Sbjct: 494 LVRLQTINLSFNRFKMLP 511



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 1/82 (1%)

Query: 1   MLKKMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQ 60
           +LK++     ++     E ++  +  L L L  N L  +P E+  L+ L+ +DLS N   
Sbjct: 266 LLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDIS 325

Query: 61  DFPEQLTALPALETINLEENEI 82
             P  L  L  L+ + LE N +
Sbjct: 326 SLPYSLGNL-HLKFLALEGNPL 346



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 7/76 (9%)

Query: 39  LPSE----VSALQHLKAIDLSRNQFQDFPEQL---TALPALETINLEENEIVDVPVEKLA 91
           LPSE    + A+  LK +D S  Q    P+++        + +IN  +N++ ++P   + 
Sbjct: 387 LPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVE 446

Query: 92  AMPALRSINLRFNPLN 107
               +  ++L FN L+
Sbjct: 447 LKEMVSDVDLSFNKLS 462


>gi|37221175 PH domain and leucine rich repeat protein phosphatase
           [Homo sapiens]
          Length = 1205

 Score = 54.7 bits (130), Expect = 2e-08
 Identities = 26/74 (35%), Positives = 45/74 (60%)

Query: 31  LEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKL 90
           L+GNFL  LP+E+  ++ L  + LS N+F D PE L  L A++ + +  N +  + ++ L
Sbjct: 232 LDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQAL 291

Query: 91  AAMPALRSINLRFN 104
             MP ++ ++LR N
Sbjct: 292 RKMPHIKHVDLRLN 305



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 8/70 (11%)

Query: 25  DTLELHLEGNFLHRLPS--------EVSALQHLKAIDLSRNQFQDFPEQLTALPALETIN 76
           D   L+L+ NFL + PS        E+     LK+++LS N   DFP  + ++P L  +N
Sbjct: 149 DLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELN 208

Query: 77  LEENEIVDVP 86
           +  N +  VP
Sbjct: 209 VSCNALRSVP 218



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP- 86
           EL++  N L  +P+ V  + +L+   L  N  Q  P +L  +  L  + L  NE  D+P 
Sbjct: 206 ELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPE 265

Query: 87  -VEKLAAMPAL 96
            +EKL A+  L
Sbjct: 266 VLEKLTAVDKL 276



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           E+ L GN L  +P+ +   + +  +    N  + FPE +  LP ++ ++L  NE+ +V +
Sbjct: 552 EIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE-VMQLPEIKCVDLSCNELSEVTL 610

Query: 88  EKLAAMPALRSINLRFNP 105
            +    P L+ ++L  NP
Sbjct: 611 PE-NLPPKLQELDLTGNP 627



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 13  ARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPAL 72
           AR +NE ++  +    L+L  N L   P  V ++  L  +++S N  +  P  +  +  L
Sbjct: 169 ARGLNE-LQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNL 227

Query: 73  ETINLEENEIVDVPVEKLAAMPALRSINLRFN 104
           +T  L+ N +  +P E L  M  L  + L FN
Sbjct: 228 QTFLLDGNFLQSLPAE-LENMKQLSYLGLSFN 258



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 10/112 (8%)

Query: 4   KMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSAL---------QHLKAIDL 54
           K+G+  A +   +       +  + L + G FL  L +  + L          +L  +D+
Sbjct: 330 KLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYLSYMDV 389

Query: 55  SRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
           SRN+ ++ PE +     LE +++  N+I ++P  +L    +LR +    N L
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPA-RLFCNSSLRKLLAGHNQL 440



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%)

Query: 21  ESGSDTLELHLEGNFL-HRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEE 79
           E+ S   EL+L  N L  +    ++   HLK + ++ N+ Q FP       A +   LEE
Sbjct: 497 ETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFP-------ASKMAKLEE 549

Query: 80  NEIVDVPVEKLAAMP 94
            E +D+   KL A+P
Sbjct: 550 LEEIDLSGNKLKAIP 564



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 13/49 (26%), Positives = 25/49 (51%), Gaps = 2/49 (4%)

Query: 39  LPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           +  EV  LQH+  +DL  N+  D    +     +E ++ E N++V + +
Sbjct: 311 IADEVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDI 357


>gi|28872863 CCR4-NOT transcription complex, subunit 6 [Homo
           sapiens]
          Length = 557

 Score = 53.5 bits (127), Expect = 5e-08
 Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 10/117 (8%)

Query: 14  RKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALE 73
           R ++ ++ S +    LHL  N L R+PS+++ L +L  +DLS N+ +  P +L  + +L 
Sbjct: 41  RSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLR 100

Query: 74  TINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR 130
            ++L  N +  +P E L  +  L+++ L+ NPL  ++          ++   P+G R
Sbjct: 101 ELHLNNNLLRVLPFE-LGKLFQLQTLGLKGNPLTQDI---------LNLYQEPDGTR 147


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 53.1 bits (126), Expect = 6e-08
 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 7   EAVARVARKVNETVESG--SDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPE 64
           E V R + K    +  G   D  EL+LEGN L  +P E+SAL+HL  IDLS N       
Sbjct: 733 ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTN 792

Query: 65  -QLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNA 108
              + +  L T+ L  N +  +PV     + +LR + L  N +++
Sbjct: 793 YTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISS 837



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 2/83 (2%)

Query: 27  LELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDF-PEQLTALPALETINLEENEIVD 84
           +E+ LE N +  +P+   +  + LK ID+S+NQ  D  P+    L +L ++ L  N+I +
Sbjct: 310 VEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITE 369

Query: 85  VPVEKLAAMPALRSINLRFNPLN 107
           +       + +L+ + L  N +N
Sbjct: 370 IAKGLFDGLVSLQLLLLNANKIN 392



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 28/104 (26%), Positives = 37/104 (35%), Gaps = 26/104 (25%)

Query: 29  LHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQ---------------------- 65
           L L  N L  LP  +  +   L  +DLS NQ Q  P +                      
Sbjct: 114 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 173

Query: 66  ---LTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
                AL  LE + L  N I  + V     MP +R++ L  N L
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 6/99 (6%)

Query: 15  KVNETVESGSD----TLELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTA- 68
           K+ E  E   D      EL L GN L  +   V   L  LK + L  N          A 
Sbjct: 568 KIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAG 627

Query: 69  LPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLN 107
           L ++  ++L +N I  +       + +L +INL  NP N
Sbjct: 628 LSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFN 666


>gi|194394161 leucine rich repeat containing 57 [Homo sapiens]
          Length = 239

 Score = 53.1 bits (126), Expect = 6e-08
 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 2/93 (2%)

Query: 14  RKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALE 73
           R++  T    S    L L GN L  LP ++ +L+HL  +DLS+NQ +  P+ +  L  +E
Sbjct: 98  RELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQVIE 157

Query: 74  TINLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
            +NL +N+I  + V K++  P L+ + L  N L
Sbjct: 158 -LNLNQNQISQISV-KISCCPRLKILRLEENCL 188



 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 3/92 (3%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LPS    L  LK + LS NQ    P QL +L  L+ ++L +N+I  +P +
Sbjct: 90  LSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIP-D 148

Query: 89  KLAAMPALRSINLRFNPLN-AEVRVIAPPLIK 119
            +  +  +  +NL  N ++   V++   P +K
Sbjct: 149 SVGELQVI-ELNLNQNQISQISVKISCCPRLK 179



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 24  SDTLELHLEGNFLHRLPSE-VSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI 82
           S+   + L  N +  LP   +     LK++ L+ N+    P+++  L  LET++L  N +
Sbjct: 38  SNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHL 97

Query: 83  VDVPVEKLAAMPALRSINLRFNPLNA 108
            ++P      + AL++++L  N L A
Sbjct: 98  RELP-STFGQLSALKTLSLSGNQLGA 122


>gi|115583679 CCR4-NOT transcription complex, subunit 6-like [Homo
           sapiens]
          Length = 555

 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 31/117 (26%), Positives = 62/117 (52%), Gaps = 10/117 (8%)

Query: 14  RKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALE 73
           R ++ ++ S +    LHL  N+L R+P +++ L +L  +DLS N+ +  P +L  + +L 
Sbjct: 46  RSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLR 105

Query: 74  TINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGAR 130
            + L  N +  +P E L  +  L+++ L+ NPL+ ++          ++   P+G R
Sbjct: 106 ELLLNNNLLRVLPYE-LGRLFQLQTLGLKGNPLSQDI---------LNLYQDPDGTR 152


>gi|122937315 leucine-rich repeats and IQ motif containing 4 [Homo
           sapiens]
          Length = 560

 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L GN L  LP E+     L+ I L RNQF+ FP++L  L  LE I+L+EN+I  +P E
Sbjct: 147 LGLTGNHLKCLPKEIVNQTKLREIYLKRNQFEVFPQELCVLYTLEIIDLDENKIGAIP-E 205

Query: 89  KLAAMPALRSINLRFNPL 106
           ++  +  L+   +  N L
Sbjct: 206 EIGHLTGLQKFYMASNNL 223



 Score = 46.6 bits (109), Expect = 6e-06
 Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 1/91 (1%)

Query: 16  VNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETI 75
           V E +       EL++E N L  LP  + ++ +L+ +D   N  +  P+ +    AL+ +
Sbjct: 390 VPEHIRKLQSLKELYIENNHLEYLPVSLGSMPNLEVLDCRHNLLKQLPDAICQAQALKEL 449

Query: 76  NLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
            LE+N +  +P E L ++  L+ + L  NP+
Sbjct: 450 RLEDNLLTHLP-ENLDSLVNLKVLTLMDNPM 479



 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L    LHRL      L +L+ +DLS+N     P Q+ AL  LE + L++N+I  +P E
Sbjct: 285 LYLGNTGLHRLRGSFRCLVNLRFLDLSQNHLHHCPLQICALKNLEVLGLDDNKIGQLPSE 344

Query: 89  KLAAMPALRSINLRFN 104
            L ++  L+ + L  N
Sbjct: 345 -LGSLSKLKILGLTGN 359



 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 21/74 (28%), Positives = 41/74 (55%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           E+HLE N +  +P E+  L++++ + L +N  +     L  L +LE+++L  N I    +
Sbjct: 52  EVHLENNQIEEIPQEIQRLKNIRVLYLDKNNLRSLCPALGLLSSLESLDLSYNPIFSSSL 111

Query: 88  EKLAAMPALRSINL 101
             ++ + ALR + L
Sbjct: 112 VVVSFLHALRELRL 125



 Score = 43.5 bits (101), Expect = 5e-05
 Identities = 25/81 (30%), Positives = 49/81 (60%), Gaps = 4/81 (4%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENE---IVDV 85
           L L+ N + +LPSE+ +L  LK + L+ N+F  FPE++ +L +LE + + +++   +  V
Sbjct: 331 LGLDDNKIGQLPSELGSLSKLKILGLTGNEFLSFPEEVLSLASLEKLYIGQDQGFKLTYV 390

Query: 86  PVEKLAAMPALRSINLRFNPL 106
           P E +  + +L+ + +  N L
Sbjct: 391 P-EHIRKLQSLKELYIENNHL 410



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 20/97 (20%), Positives = 45/97 (46%), Gaps = 1/97 (1%)

Query: 17  NETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETIN 76
           N+       T  +      L  +P E+     L+ + L  NQ ++ P+++  L  +  + 
Sbjct: 18  NDPQHVNDRTFFIDASNQSLTAIPLEIFTFTELEEVHLENNQIEEIPQEIQRLKNIRVLY 77

Query: 77  LEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVI 113
           L++N +  +    L  + +L S++L +NP+ +   V+
Sbjct: 78  LDKNNLRSL-CPALGLLSSLESLDLSYNPIFSSSLVV 113



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           E++L+ N     P E+  L  L+ IDL  N+    PE++  L  L+   +  N +  +P 
Sbjct: 169 EIYLKRNQFEVFPQELCVLYTLEIIDLDENKIGAIPEEIGHLTGLQKFYMASNNLPVLPA 228

Query: 88  EKLAAMPALRSINLRFNPLNA 108
             L     L  ++L  N L++
Sbjct: 229 -SLCQCSQLSVLDLSHNLLHS 248



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 34  NFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLA 91
           N L +LP  +   Q LK + L  N     PE L +L  L+ + L +N + + P E  A
Sbjct: 431 NLLKQLPDAICQAQALKELRLEDNLLTHLPENLDSLVNLKVLTLMDNPMEEPPKEVCA 488



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 16/59 (27%), Positives = 25/59 (42%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           + ++  N L  LP+ +     L  +DLS N     P+    L  +  I L  N +  VP
Sbjct: 215 KFYMASNNLPVLPASLCQCSQLSVLDLSHNLLHSIPKSFAELRKMTEIGLSGNRLEKVP 273


>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
          Length = 582

 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 1/99 (1%)

Query: 16  VNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETI 75
           V + +++ S    L +  N + +LP+E+  L +L  +D++ NQ +  P+++     +  +
Sbjct: 207 VEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNL 266

Query: 76  NLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIA 114
           +L+ NE++D+P + +  + +L  + LR+N L+A  R +A
Sbjct: 267 DLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLA 304



 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 2/107 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL+L  N L  LP+EV  L +L  + LS N     P+ L  L  L  ++L  N++ ++P 
Sbjct: 127 ELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP- 185

Query: 88  EKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGARAPLP 134
             +  + +L ++ LRFN +    + I   L K  ML   E     LP
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDI-KNLSKLSMLSIRENKIKQLP 231



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 10  ARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTAL 69
           A V +++N+  E  S  + L L    +H LPS +  L  L  + L  N+ Q  P ++  L
Sbjct: 88  AEVIKELNKCREENS--MRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCL 145

Query: 70  PALETINLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
             L T+ L EN +  +P + L  +  LR ++LR N L
Sbjct: 146 VNLMTLALSENSLTSLP-DSLDNLKKLRMLDLRHNKL 181



 Score = 44.3 bits (103), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           +EL+L  N L ++P +VS L  L+ + LS N  +  P  L  L  L  ++LEEN++  +P
Sbjct: 405 VELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLP 464

Query: 87  VEKLAAMPALRSINLRFNPLNAEVRVI 113
            E +A +  L+ + L  N L    R I
Sbjct: 465 NE-IAYLKDLQKLVLTNNQLTTLPRGI 490



 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 26/76 (34%), Positives = 36/76 (47%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L+ N L  LP  +  L  L  + L  N+    P  L    ALE +NLE N I  +P  
Sbjct: 266 LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPES 325

Query: 89  KLAAMPALRSINLRFN 104
            L+++  L S+ L  N
Sbjct: 326 LLSSLVKLNSLTLARN 341



 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL LE N L  LP+E++ L+ L+ + L+ NQ    P  +  L  L  + L EN +  +P 
Sbjct: 452 ELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP- 510

Query: 88  EKLAAMPALRSINLRFNP 105
           E++  +  L  + L  NP
Sbjct: 511 EEIGTLENLEELYLNDNP 528



 Score = 40.0 bits (92), Expect = 6e-04
 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 15  KVNETVESGSDTLE-LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALE 73
           K+ E V SG  +LE L L  N L +LP  +  L+ L+ +DL  N+ +  P ++  L  L+
Sbjct: 416 KIPEDV-SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQ 474

Query: 74  TINLEENEIVDVP 86
            + L  N++  +P
Sbjct: 475 KLVLTNNQLTTLP 487



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI--VD 84
           + L L  N L  LP  +  L+ L+ +DL  N+ ++ P  +  L +L T+ L  N I  V+
Sbjct: 149 MTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVE 208

Query: 85  VPVEKLAAMPALRSINLRFNPLNAEV 110
             ++ L+ +  L     +   L AE+
Sbjct: 209 KDIKNLSKLSMLSIRENKIKQLPAEI 234



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           +L+++ N L  LP +      +  ++L+ NQ    PE ++ L +LE + L  N +  +P 
Sbjct: 383 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP- 441

Query: 88  EKLAAMPALRSINLRFNPLNAEVRVIA 114
             L  +  LR ++L  N L +    IA
Sbjct: 442 HGLGNLRKLRELDLEENKLESLPNEIA 468



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 24  SDTLELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI 82
           S    L++E N ++++P  + S  + L  +++  NQ    P       ++  +NL  N++
Sbjct: 355 STIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQL 414

Query: 83  VDVPVEKLAAMPALRSINLRFNPL 106
             +P E ++ + +L  + L  N L
Sbjct: 415 TKIP-EDVSGLVSLEVLILSNNLL 437


>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
           [Homo sapiens]
          Length = 1052

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 35/58 (60%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           L L+ N L  LP++ S LQ LK ++LS N F++FP  L  L  LE + L  N++  VP
Sbjct: 255 LMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVP 312



 Score = 50.1 bits (118), Expect = 5e-07
 Identities = 27/89 (30%), Positives = 51/89 (57%), Gaps = 1/89 (1%)

Query: 18  ETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINL 77
           E V +  +  +L+L  N L  LP+++ AL HL+ +D+S N+    P+ L+ L  L T+++
Sbjct: 129 EVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDV 188

Query: 78  EENEIVDVPVEKLAAMPALRSINLRFNPL 106
           + N++   P  +L  + AL  +++  N L
Sbjct: 189 DHNQLTAFP-RQLLQLVALEELDVSSNRL 216



 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 1/70 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL +  N L  LP  +S L  L+ +D+  NQ   FP QL  L ALE +++  N +  +P 
Sbjct: 162 ELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLP- 220

Query: 88  EKLAAMPALR 97
           E ++A+ AL+
Sbjct: 221 EDISALRALK 230



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL +  N L  LP ++SAL+ LK + LS  +    P     L +LE++ L+ N +  +P 
Sbjct: 208 ELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPA 267

Query: 88  EKLAAMPALRSINLRFN 104
           +  + +  L+ +NL  N
Sbjct: 268 Q-FSCLQRLKMLNLSSN 283



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 20/59 (33%), Positives = 32/59 (54%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           EL+L  N L  +PS +S L  L  + L  N+ +  P+ +  L  LE + L+ N+I  +P
Sbjct: 300 ELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLP 358



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 25  DTLELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTAL-PALETINLEENEI 82
           D   L+L  N L  +P  + SAL  L+ + L RN+F   P  +  L   L  +++  N +
Sbjct: 64  DIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRL 123

Query: 83  VDVPVEKLAAMPALRSINLRFNPLNA 108
             +  E ++A+  LR +NL  N L A
Sbjct: 124 TALGAEVVSALRELRKLNLSHNQLPA 149



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 1/80 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L ++ N L   P ++  L  L+ +D+S N+ +  PE ++AL AL+ + L   E+  +P  
Sbjct: 186 LDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPA- 244

Query: 89  KLAAMPALRSINLRFNPLNA 108
               + +L S+ L  N L A
Sbjct: 245 GFCELASLESLMLDNNGLQA 264



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L  N     P+ +  L  L+ + LSRNQ    P  ++ L  L T+ L+ N I  +P +
Sbjct: 278 LNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLP-D 336

Query: 89  KLAAMPALRSINLRFNPL 106
            +  +  L  + L+ N +
Sbjct: 337 SIVELTGLEELVLQGNQI 354



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L G  L  LP+    L  L+++ L  N  Q  P Q + L  L+ +NL  N   + P  
Sbjct: 232 LWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPA- 290

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA 114
            L  +  L  + L  N L +   +I+
Sbjct: 291 ALLPLAGLEELYLSRNQLTSVPSLIS 316



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 16/62 (25%), Positives = 28/62 (45%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           L L L+ N +  LP  +  L  L+ + L  NQ    P+    L  +    +++N ++  P
Sbjct: 322 LTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPP 381

Query: 87  VE 88
            E
Sbjct: 382 YE 383


>gi|14249428 leucine-rich repeats and calponin homology (CH) domain
           containing 3 [Homo sapiens]
          Length = 712

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 1/64 (1%)

Query: 34  NFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAM 93
           N L  LP E+  L+HL  +D+S N+ Q  P Q+  L AL  +N+  N +V +P E+LA +
Sbjct: 160 NKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLP-EELAEL 218

Query: 94  PALR 97
           P +R
Sbjct: 219 PLIR 222



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           +EL +  N +  +PS++  L+ L+ +++ RN     PE+L  LP +  ++   N+I  +P
Sbjct: 176 MELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIR-LDFSCNKITTIP 234

Query: 87  VEKLAAMPALRSINLRFNPLNA 108
           V     +  L++I L  NPL +
Sbjct: 235 V-CYRNLRHLQTITLDNNPLQS 255



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 24/116 (20%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L  N +  +P  +  LQ L  +++SRNQ    P  L  LP L+ +    N++V +P E
Sbjct: 110 LNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIASNNKLVSLPEE 168

Query: 89  ----------------------KLAAMPALRSINLRFNPL-NAEVRVIAPPLIKFD 121
                                 ++  + ALR +N+R N L +    +   PLI+ D
Sbjct: 169 IGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIRLD 224



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 19/64 (29%), Positives = 32/64 (50%)

Query: 24  SDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 83
           +DT    L  N L  +P E      L+ ++L +N  +  PE +  L AL  +N+  N++ 
Sbjct: 82  TDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLS 141

Query: 84  DVPV 87
            +PV
Sbjct: 142 TLPV 145


>gi|238908508 leucine-rich repeat and death domain-containing
           protein [Homo sapiens]
          Length = 860

 Score = 50.4 bits (119), Expect = 4e-07
 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L++  N +  +P E+S L +++ +    N  ++FP  L  L  LE ++L +N++  +P +
Sbjct: 216 LNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIP-D 274

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA--PPLIKFDM 122
            L ++  LR +NL +N L    + +   P LI  D+
Sbjct: 275 TLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDL 310



 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           +L    N++   PS++  L +L+ + L +N+ +  P+ L +L  L  +NLE N++   P 
Sbjct: 238 QLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFP- 296

Query: 88  EKLAAMPALRSINLRFNPLNA 108
           + L  +P L S++L  N +++
Sbjct: 297 KALCFLPKLISLDLTGNLISS 317



 Score = 43.5 bits (101), Expect = 5e-05
 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 4/90 (4%)

Query: 15  KVNETVESGSDTLELH---LEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPA 71
           ++ +   S S+ + LH   L  N     P E+  L++L+ +DLS NQ Q     +  L  
Sbjct: 544 QIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKG 603

Query: 72  LETINLEENEIVDVPVEKLAAMPALRSINL 101
           ++ +N   N+ +  P+E L  + +L  +N+
Sbjct: 604 IQKLNFSSNQFIHFPIE-LCQLQSLEQLNI 632



 Score = 43.5 bits (101), Expect = 5e-05
 Identities = 25/78 (32%), Positives = 43/78 (55%), Gaps = 1/78 (1%)

Query: 31  LEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKL 90
           ++G  L RLP E+S +  LK +D+S N  ++ P  +  L  L +++   N+I  +P   L
Sbjct: 635 IKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLP-PSL 693

Query: 91  AAMPALRSINLRFNPLNA 108
            ++  L+ +NL  N L A
Sbjct: 694 LSLNDLQQLNLSGNNLTA 711



 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 26/104 (25%), Positives = 56/104 (53%), Gaps = 2/104 (1%)

Query: 5   MGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPE 64
           +GE   +V+ +  + +  G+D   ++LE   L   P ++  ++++K + L +NQ + F  
Sbjct: 122 VGEVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQG 181

Query: 65  QLTA-LPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLN 107
             +  L  LE ++L+EN +  +P E +  +  LR +N+  N ++
Sbjct: 182 ADSGDLLGLEILSLQENGLSSLPSE-IQLLHNLRILNVSHNHIS 224



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL +  N +  +P  +  L++L ++    NQ    P  L +L  L+ +NL  N +  +P 
Sbjct: 655 ELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALP- 713

Query: 88  EKLAAMPALRSINLRFNPL 106
             +  + +L+ IN   NPL
Sbjct: 714 SAIYNIFSLKEINFDDNPL 732



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  +P  + +L+ L+ ++L  NQ   FP+ L  LP L +++L  N I  +P E
Sbjct: 262 LSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKE 321



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEE---NEIVDV 85
           L L  N L ++ S++  L+ ++ ++ S NQF  FP +L  L +LE +N+ +    ++  +
Sbjct: 584 LDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRL 643

Query: 86  PVEKLAAMPALRSINLRFNPL 106
           P E L+ M  L+ +++  N +
Sbjct: 644 PGE-LSNMTQLKELDISNNAI 663



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/75 (29%), Positives = 39/75 (52%)

Query: 14  RKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALE 73
           R + +T+ S      L+LE N L   P  +  L  L ++DL+ N     P+++  L  LE
Sbjct: 270 RHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLE 329

Query: 74  TINLEENEIVDVPVE 88
           T+ ++ N++  + VE
Sbjct: 330 TLLMDHNKLTFLAVE 344



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 1/76 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N + ++P+ +S +  L  + L  N+F+ FP +L  L  L+ ++L EN++  +  +
Sbjct: 538 LDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSD 597

Query: 89  KLAAMPALRSINLRFN 104
            +  +  ++ +N   N
Sbjct: 598 -ICNLKGIQKLNFSSN 612



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 17/60 (28%), Positives = 30/60 (50%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP  +  L +L+ + ++RN      + ++ L  + ++    N I DVP+E
Sbjct: 400 LSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNNICSLEFSGNIITDVPIE 459



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           + L L GN +  LP E+  L++L+ + +  N+      ++  L  ++ + L +N++ +V 
Sbjct: 306 ISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKL-EVI 364

Query: 87  VEKLAAMPALRSINLRFNPL 106
             K+     LR + L  N L
Sbjct: 365 SHKIENFRELRILILDKNLL 384



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           L L L  N L        +L +LK +DL +NQ +  P  ++ + +L  + L  N+    P
Sbjct: 513 LHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFP 572

Query: 87  VEKLAAMPALRSINLRFNPL 106
            E L  +  L+ ++L  N L
Sbjct: 573 RE-LCTLENLQVLDLSENQL 591



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           +LH+  N + ++   +S L ++ +++ S N   D P ++     +  I L  N+I+  P+
Sbjct: 422 KLHVNRNNMVKITDCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPL 481

Query: 88  EKLAAMPALRSINLRFN 104
             L A+ +L  +++  N
Sbjct: 482 -GLCALDSLYYLSVNGN 497



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 17/52 (32%), Positives = 25/52 (48%)

Query: 24  SDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETI 75
           +D  +L+L GN L  LPS +  +  LK I+   N     P ++     L TI
Sbjct: 697 NDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNPLLRPPVEICKGKQLYTI 748


>gi|40254924 leucine rich repeat containing 59 [Homo sapiens]
          Length = 307

 Score = 50.4 bits (119), Expect = 4e-07
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LPS+   L HL  +DLS+N+ Q  P     L  L+ ++L  N++V +PV 
Sbjct: 44  LDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPV- 102

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA 114
             A +  L+ ++L+ NPL+  +  +A
Sbjct: 103 SFAQLKNLKWLDLKDNPLDPVLAKVA 128



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 16/56 (28%), Positives = 31/56 (55%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI 82
           ++L L  N L +LP++   L +L+ +DL  N+    P     L  L+ ++L++N +
Sbjct: 65  VKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score = 50.4 bits (119), Expect = 4e-07
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 24  SDTLELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI 82
           S  + LHL  N +  L       L +L+ +DL+ N   +FP+ + ALP+L+ +    N I
Sbjct: 201 SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSI 260

Query: 83  VDVPVEKLAAMPALRSINLRFNPLN 107
             +P       P LR+I+L  NPL+
Sbjct: 261 SVIPDGAFDGNPLLRTIHLYDNPLS 285



 Score = 42.7 bits (99), Expect = 9e-05
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 2/82 (2%)

Query: 29  LHLEGNFLHRLPSE-VSALQHLKAIDLSRNQFQDFPEQ-LTALPALETINLEENEIVDVP 86
           L L+ N L  +PSE +  L  L+++ L  N     PE     L  L  + L++N + +VP
Sbjct: 110 LTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVP 169

Query: 87  VEKLAAMPALRSINLRFNPLNA 108
           V  L+ +P L+++ L  N +++
Sbjct: 170 VHPLSNLPTLQALTLALNKISS 191



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 29  LHLEGNFLHRLPSEVSALQH-LKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           L L G  +  +P+ +   Q  L+ +DLS N  +D P       ALE I+L+ N+I  +  
Sbjct: 324 LTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS-FNGCHALEEISLQRNQIYQIKE 382

Query: 88  EKLAAMPALRSINLRFN 104
                + +LR ++L  N
Sbjct: 383 GTFQGLISLRILDLSRN 399



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 2/94 (2%)

Query: 17  NETVESGSDTLELHLEGNFLHRLPSE-VSALQHLKAIDLSRNQFQDFP-EQLTALPALET 74
           +E +   S    L L+ N +  +P +    L  L+ + L  N   + P   L+ LP L+ 
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181

Query: 75  INLEENEIVDVPVEKLAAMPALRSINLRFNPLNA 108
           + L  N+I  +P      + +L  ++L  N + +
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRS 215


>gi|21389431 leucine rich repeat containing 39 [Homo sapiens]
          Length = 335

 Score = 50.1 bits (118), Expect = 5e-07
 Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 3/88 (3%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L +  N L +LP  +  +Q+L  + L RN+    P+ ++ +  L T+ L  N++ D+PV 
Sbjct: 204 LDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPV- 262

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIAPP 116
            +  M  LR +N R NPL  +++V  PP
Sbjct: 263 CMEEMANLRFVNFRDNPL--KLKVSLPP 288



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 1/76 (1%)

Query: 39  LPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRS 98
           LP E+S L  L  +DLS N F   P  +  +PALE +++  N++  +P + +  M  L +
Sbjct: 168 LPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLP-DTIERMQNLHT 226

Query: 99  INLRFNPLNAEVRVIA 114
           + L+ N +    + I+
Sbjct: 227 LWLQRNEITCLPQTIS 242



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           +LH  G  L ++P  +   Q+L  +DLSRN   + P  +  L  L+ + L  N+I  VP 
Sbjct: 89  QLHRTG--LLKIPEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPK 146

Query: 88  EKLAAMPALRSINLRFN 104
           E L+   +L  + L  N
Sbjct: 147 E-LSNCASLEKLELAVN 162



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 2/80 (2%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQ-FQDFPEQLTALPALETINLEENEIVDVP 86
           EL L  N +  +P E+S    L+ ++L+ N+   D P++L+ L  L  ++L  N+   +P
Sbjct: 133 ELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIP 192

Query: 87  VEKLAAMPALRSINLRFNPL 106
           +  L  MPAL  +++  N L
Sbjct: 193 LAVL-NMPALEWLDMGSNKL 211



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 18/65 (27%), Positives = 34/65 (52%)

Query: 18  ETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINL 77
           +T+E   +   L L+ N +  LP  +S +++L  + LS N+ QD P  +  +  L  +N 
Sbjct: 216 DTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNF 275

Query: 78  EENEI 82
            +N +
Sbjct: 276 RDNPL 280



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 1/92 (1%)

Query: 15  KVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALET 74
           K+ E V      + L +E      LPS +  L  L+   L R      PE +     L  
Sbjct: 51  KLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIV 110

Query: 75  INLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
           ++L  N I ++P   +  +  L+ + L +N +
Sbjct: 111 LDLSRNTISEIP-PGIGLLTRLQELILSYNKI 141


>gi|167466264 leucine rich repeat containing 18 [Homo sapiens]
          Length = 261

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 24  SDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 83
           SD  EL L  N + ++P  +S  Q+L+ +DL  N     PE +  + +L  +N+  N + 
Sbjct: 50  SDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLT 109

Query: 84  D--VPVEKLAAMPALRSINLRFNPLNA 108
              +PVE L  +  +R++NL  N L++
Sbjct: 110 SNGLPVE-LKQLKNIRAVNLGLNHLDS 135



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 11  RVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALP 70
           +VAR   +    G   L+L   G  +   P  +  L  +  +DLSRN  +  P+ ++   
Sbjct: 16  KVARNCIKITFDGKKRLDLSKMG--ITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQ 73

Query: 71  ALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNA 108
            L  ++L  N I  +P E +  M +L  +N+  N L +
Sbjct: 74  NLRWLDLHSNYIDKLP-ESIGQMTSLLYLNVSNNRLTS 110


>gi|41582239 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 43  VSALQHLKAIDLSRNQFQDFP-EQLTALPALETINLEENEIVDVPVEKLAAMPALRSINL 101
           +++L HLK++DLS N   DF    L  L AL+ + ++ NE+  +P +   ++ ALRS+ L
Sbjct: 94  LASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQL 153

Query: 102 RFNPLNAEVRVIAPPLIKFDMLMSPE 127
             N L+        PL     L   E
Sbjct: 154 NHNRLHTLAEGTFTPLTALSHLQINE 179


>gi|5031809 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 48.1 bits (113), Expect = 2e-06
 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 43  VSALQHLKAIDLSRNQFQDFP-EQLTALPALETINLEENEIVDVPVEKLAAMPALRSINL 101
           +++L HLK++DLS N   DF    L  L AL+ + ++ NE+  +P +   ++ ALRS+ L
Sbjct: 94  LASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQL 153

Query: 102 RFNPLNAEVRVIAPPLIKFDMLMSPE 127
             N L+        PL     L   E
Sbjct: 154 NHNRLHTLAEGTFTPLTALSHLQINE 179


>gi|4504379 leucine-rich repeat-containing G protein-coupled
           receptor 5 [Homo sapiens]
          Length = 907

 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 6/106 (5%)

Query: 22  SGSDTLE-LHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTALPALETINLEE 79
           +G+  LE L L G  +  LP  V + L +L+ +DLS N  +D P   +    L+ I+L  
Sbjct: 325 TGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRH 383

Query: 80  NEIVDVPVEKLAAMPALRSINLRFNP---LNAEVRVIAPPLIKFDM 122
           NEI ++ V+    + +LRS+NL +N    ++       P LIK D+
Sbjct: 384 NEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDL 429



 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 24  SDTLELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI 82
           S  + LHL  N +H L  +    L  L+ +DL+ N   +FP  +  L  L+ +    N I
Sbjct: 210 SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNI 269

Query: 83  VDVPVEKLAAMPALRSINLRFNPL 106
             +P +     P+L +I+   NP+
Sbjct: 270 RSIPEKAFVGNPSLITIHFYDNPI 293



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFP-EQLTALPALETINLEENEIVDVPV 87
           L L  N L  LPS  S  Q L+ IDL  N+  +   +    L +L ++NL  N+I  +  
Sbjct: 357 LDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHP 415

Query: 88  EKLAAMPALRSINLRFNPLNA 108
              + +P+L  ++L  N L++
Sbjct: 416 NAFSTLPSLIKLDLSSNLLSS 436


>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
          Length = 583

 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 26/72 (36%), Positives = 38/72 (52%)

Query: 28  ELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPV 87
           EL    N L  L  +++ L  LK +DLS NQ  + P +L   P L+ IN   N++ D  +
Sbjct: 183 ELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRL 242

Query: 88  EKLAAMPALRSI 99
           EK+ +    RSI
Sbjct: 243 EKMVSGCQTRSI 254



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 7/77 (9%)

Query: 39  LPSEVSALQHLKAIDLSRNQFQDFPE-------QLTALPALETINLEENEIVDVPVEKLA 91
           L  E+  L  L+ +DLS N  +  P        +   LP L+++NL  N + ++P +   
Sbjct: 91  LSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLAR 150

Query: 92  AMPALRSINLRFNPLNA 108
             P L+S+NL  N L++
Sbjct: 151 CAPRLQSLNLTGNCLDS 167


>gi|153792305 leucine rich repeat containing 58 [Homo sapiens]
          Length = 371

 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L GN L  +P+E+  LQ L+ + L  N  ++ P +L  LP+L  + L +N+I  +P  
Sbjct: 148 LSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIP-P 206

Query: 89  KLAAMPALRSINLRFNPL 106
           +L+ + +LRS++L  N L
Sbjct: 207 QLSQLHSLRSLSLHNNLL 224



 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L GNF+  +P E+  L  L  + L  N+ Q  P QL+ L +L +++L  N +  +P E
Sbjct: 171 LYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPRE 230

Query: 89  KLAAMPALRSINLRFNPL 106
            L  +  L  ++LR NPL
Sbjct: 231 ILNLI-HLEELSLRGNPL 247



 Score = 44.3 bits (103), Expect = 3e-05
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 5/97 (5%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+L GN    +P+ +  L+ L+ + L  NQ Q  P ++  L +LE + L  N I ++P E
Sbjct: 125 LNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPE 184

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMS 125
            L  +P+L  + L  N    +++ I P L +   L S
Sbjct: 185 -LGNLPSLNYLVLCDN----KIQSIPPQLSQLHSLRS 216



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 16/40 (40%), Positives = 26/40 (65%)

Query: 49  LKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L+ ++LS N FQ+ P  L  L AL+T++L  N++  +P E
Sbjct: 122 LQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAE 161



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 27  LELHLEGNFLHRLPSEV-SALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEI--V 83
           L L L  N L  LP  + S   HL+ +D+S N       +L AL  L T+  + N +   
Sbjct: 47  LRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGP 106

Query: 84  DVPVEKLAAMPALRSINL 101
               + LA  P  RS+ +
Sbjct: 107 SALPKGLAQSPLCRSLQV 124


>gi|61742786 leucine rich repeat and death domain containing protein
           isoform 3 [Homo sapiens]
          Length = 893

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           LEL+L  N L  LP+ ++ L+ L+ + L  N     P  L  LP L  ++L +N++ D+P
Sbjct: 220 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 279

Query: 87  VEKLAAMPALRSINLRFNPL 106
            E L A P +R   L+ NPL
Sbjct: 280 PELLDA-PFVR---LQGNPL 295



 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 25  DTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVD 84
           DTL   L G  L  LP+ +S L HL  +DLS N  +  P  +  +  L  + L  N + +
Sbjct: 104 DTLGACLRGA-LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSE 162

Query: 85  VPVEKLAAMPALRSINLRFNPL 106
           +P E L A+PAL  + +  N L
Sbjct: 163 LP-EALGALPALTFLTVTHNRL 183



 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP+ V  ++ L A+ LS N   + PE L ALPAL  + +  N +  +P  
Sbjct: 130 LDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLP-P 188

Query: 89  KLAAMPALRSINLRFNPLN 107
            L A+  L+ ++L  N L+
Sbjct: 189 ALGALSTLQRLDLSQNLLD 207



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 34  NFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAM 93
           N L  LP  + AL  L+ +DLS+N     P ++  L +L  +NL  N +  +P   LA +
Sbjct: 181 NRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPA-SLAGL 239

Query: 94  PALRSINLRFNPLNAEVRVIA--PPLIKFDM 122
            +LR + L  N L +    +A  P L + D+
Sbjct: 240 RSLRLLVLHSNLLASVPADLARLPLLTRLDL 270


>gi|61742784 leucine rich repeat and death domain containing protein
           isoform 1 [Homo sapiens]
          Length = 910

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           LEL+L  N L  LP+ ++ L+ L+ + L  N     P  L  LP L  ++L +N++ D+P
Sbjct: 220 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 279

Query: 87  VEKLAAMPALRSINLRFNPL 106
            E L A P +R   L+ NPL
Sbjct: 280 PELLDA-PFVR---LQGNPL 295



 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 25  DTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVD 84
           DTL   L G  L  LP+ +S L HL  +DLS N  +  P  +  +  L  + L  N + +
Sbjct: 104 DTLGACLRGA-LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSE 162

Query: 85  VPVEKLAAMPALRSINLRFNPL 106
           +P E L A+PAL  + +  N L
Sbjct: 163 LP-EALGALPALTFLTVTHNRL 183



 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP+ V  ++ L A+ LS N   + PE L ALPAL  + +  N +  +P  
Sbjct: 130 LDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLP-P 188

Query: 89  KLAAMPALRSINLRFNPLN 107
            L A+  L+ ++L  N L+
Sbjct: 189 ALGALSTLQRLDLSQNLLD 207



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 34  NFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAM 93
           N L  LP  + AL  L+ +DLS+N     P ++  L +L  +NL  N +  +P   LA +
Sbjct: 181 NRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPA-SLAGL 239

Query: 94  PALRSINLRFNPLNAEVRVIA--PPLIKFDM 122
            +LR + L  N L +    +A  P L + D+
Sbjct: 240 RSLRLLVLHSNLLASVPADLARLPLLTRLDL 270


>gi|61742782 leucine rich repeat and death domain containing protein
           isoform 2 [Homo sapiens]
          Length = 753

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 27  LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
           LEL+L  N L  LP+ ++ L+ L+ + L  N     P  L  LP L  ++L +N++ D+P
Sbjct: 74  LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 133

Query: 87  VEKLAAMPALRSINLRFNPL 106
            E L A P +R   L+ NPL
Sbjct: 134 PELLDA-PFVR---LQGNPL 149



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 34  NFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAM 93
           N L  LP  + AL  L+ +DLS+N     P ++  L +L  +NL  N +  +P   LA +
Sbjct: 35  NRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPA-SLAGL 93

Query: 94  PALRSINLRFNPLNAEVRVIA--PPLIKFDM 122
            +LR + L  N L +    +A  P L + D+
Sbjct: 94  RSLRLLVLHSNLLASVPADLARLPLLTRLDL 124



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 1/62 (1%)

Query: 46  LQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNP 105
           ++ L A+ LS N   + PE L ALPAL  + +  N +  +P   L A+  L+ ++L  N 
Sbjct: 1   MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLP-PALGALSTLQRLDLSQNL 59

Query: 106 LN 107
           L+
Sbjct: 60  LD 61


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 23/86 (26%), Positives = 50/86 (58%), Gaps = 1/86 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP ++  L  L+ +++ RNQ    P  +  L  L+T+N+++N++ ++P +
Sbjct: 86  LDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELP-D 144

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA 114
            +  + +LR++N+  N +    +++A
Sbjct: 145 TVGELRSLRTLNISGNEIQRLPQMLA 170



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 3/70 (4%)

Query: 39  LPSEVS--ALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPAL 96
           LP   S  +L  +K +DL  NQ    P+ L  L AL+ +N+E N+++ +P   +  +  L
Sbjct: 71  LPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP-RSIGNLTQL 129

Query: 97  RSINLRFNPL 106
           +++N++ N L
Sbjct: 130 QTLNVKDNKL 139


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 23/86 (26%), Positives = 50/86 (58%), Gaps = 1/86 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP ++  L  L+ +++ RNQ    P  +  L  L+T+N+++N++ ++P +
Sbjct: 86  LDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELP-D 144

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA 114
            +  + +LR++N+  N +    +++A
Sbjct: 145 TVGELRSLRTLNISGNEIQRLPQMLA 170



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 3/70 (4%)

Query: 39  LPSEVS--ALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPAL 96
           LP   S  +L  +K +DL  NQ    P+ L  L AL+ +N+E N+++ +P   +  +  L
Sbjct: 71  LPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP-RSIGNLTQL 129

Query: 97  RSINLRFNPL 106
           +++N++ N L
Sbjct: 130 QTLNVKDNKL 139


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 23/86 (26%), Positives = 50/86 (58%), Gaps = 1/86 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L L  N L  LP ++  L  L+ +++ RNQ    P  +  L  L+T+N+++N++ ++P +
Sbjct: 86  LDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELP-D 144

Query: 89  KLAAMPALRSINLRFNPLNAEVRVIA 114
            +  + +LR++N+  N +    +++A
Sbjct: 145 TVGELRSLRTLNISGNEIQRLPQMLA 170



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 3/70 (4%)

Query: 39  LPSEVS--ALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPAL 96
           LP   S  +L  +K +DL  NQ    P+ L  L AL+ +N+E N+++ +P   +  +  L
Sbjct: 71  LPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP-RSIGNLTQL 129

Query: 97  RSINLRFNPL 106
           +++N++ N L
Sbjct: 130 QTLNVKDNKL 139


>gi|63003903 leucine rich repeat containing 10 [Homo sapiens]
          Length = 277

 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 2/77 (2%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           LH   N L  LP ++  LQ L+ I LS N+  DFP  L  +P LE I+++ N I   P  
Sbjct: 149 LHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP-- 206

Query: 89  KLAAMPALRSINLRFNP 105
            LA + +L+ +    NP
Sbjct: 207 SLAHLSSLKLVIYDHNP 223



 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 1/105 (0%)

Query: 2   LKKMGEAVARVARKVNETVESGSDTLELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQD 61
           L KM +      R+    V S  + ++L+L  N L+ LP E+  LQ+L+ + L  N F+ 
Sbjct: 30  LDKMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKA 89

Query: 62  FPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPL 106
            P+ +  L  L  + L  N++ D+P E L+ +  LR++ +  N L
Sbjct: 90  LPQVVCTLKQLCILYLGNNKLCDLPSE-LSLLQNLRTLWIEANCL 133



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 29  LHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE 88
           L +E N L +LP  V  L  LK +    N  +  P QL  L  L TI L  N + D P  
Sbjct: 126 LWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPT- 184

Query: 89  KLAAMPALRSINLRFNPL 106
            L  MP L  I++ +N +
Sbjct: 185 VLLHMPFLEVIDVDWNSI 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,581,699
Number of Sequences: 37866
Number of extensions: 178603
Number of successful extensions: 1147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 540
Number of HSP's gapped (non-prelim): 603
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.