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Search of human proteins with 46094076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46094076 tsukushin [Homo sapiens]
(353 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46094076 tsukushin [Homo sapiens] 707 0.0
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 106 3e-23
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 106 3e-23
gi|88702793 slit-like 2 [Homo sapiens] 96 5e-20
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 91 2e-18
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 88 1e-17
gi|193083139 leucine rich repeat containing 32 precursor [Homo s... 87 2e-17
gi|5031707 leucine rich repeat containing 32 precursor [Homo sap... 87 2e-17
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 87 2e-17
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 87 2e-17
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 87 2e-17
gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens] 85 1e-16
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 84 2e-16
gi|41350214 asporin [Homo sapiens] 82 6e-16
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 82 6e-16
gi|194440719 chondroadherin-like [Homo sapiens] 82 6e-16
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 82 9e-16
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 81 1e-15
gi|4507531 toll-like receptor 3 [Homo sapiens] 81 2e-15
gi|225579152 insulin-like growth factor binding protein, acid la... 80 2e-15
gi|4826772 insulin-like growth factor binding protein, acid labi... 80 2e-15
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 80 2e-15
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 80 3e-15
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 80 3e-15
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 79 8e-15
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 79 8e-15
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 78 1e-14
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 77 2e-14
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 77 2e-14
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 77 3e-14
>gi|46094076 tsukushin [Homo sapiens]
Length = 353
Score = 707 bits (1826), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT 60
MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
Sbjct: 1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT 60
Query: 61 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL 120
AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
Sbjct: 61 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL 120
Query: 121 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG 180
TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
Sbjct: 121 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG 180
Query: 181 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ 240
LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
Sbjct: 181 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ 240
Query: 241 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL 300
RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
Sbjct: 241 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL 300
Query: 301 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL 353
HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
Sbjct: 301 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL 353
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 106 bits (265), Expect = 3e-23
Identities = 108/374 (28%), Positives = 162/374 (43%), Gaps = 61/374 (16%)
Query: 6 LLLLAVSGAQTTRP-------CFPGCQCEVETFGLFDSF--SLTRVDCSGLGPHIMPVPI 56
LLL V+GA P C P C C++ + S T VDC+ L +P +
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 57 PLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLRYLESLDL 115
P T L L SN + V++S L GY L LDLS N + F L L SL L
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHL 124
Query: 116 SHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVD----------- 163
N LT L SF + L ++ L+HNQL ++ AF+ S LH++
Sbjct: 125 EENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRW 184
Query: 164 -----------LSHNLIHRLVPHPTR----------AGLPA-----------PTIQSLNL 191
+ N + ++ R AG+ +++SL+
Sbjct: 185 FEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSF 244
Query: 192 AWNRLHAVPN--LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPS 248
N+L VP L +P L++L L+ NPL +GPG FA + L L L +++ L +
Sbjct: 245 YDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKF 304
Query: 249 GFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSV 308
LP L LD++ NP+L++ F L ++ L L+ L L + + LP LQ V
Sbjct: 305 ALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEV 364
Query: 309 SV-GQDVRCRRLVR 321
+ G +RC ++R
Sbjct: 365 GLHGNPIRCDCVIR 378
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 106 bits (265), Expect = 3e-23
Identities = 108/374 (28%), Positives = 162/374 (43%), Gaps = 61/374 (16%)
Query: 6 LLLLAVSGAQTTRP-------CFPGCQCEVETFGLFDSF--SLTRVDCSGLGPHIMPVPI 56
LLL V+GA P C P C C++ + S T VDC+ L +P +
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 57 PLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLRYLESLDL 115
P T L L SN + V++S L GY L LDLS N + F L L SL L
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHL 124
Query: 116 SHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVD----------- 163
N LT L SF + L ++ L+HNQL ++ AF+ S LH++
Sbjct: 125 EENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRW 184
Query: 164 -----------LSHNLIHRLVPHPTR----------AGLPA-----------PTIQSLNL 191
+ N + ++ R AG+ +++SL+
Sbjct: 185 FEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSF 244
Query: 192 AWNRLHAVPN--LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPS 248
N+L VP L +P L++L L+ NPL +GPG FA + L L L +++ L +
Sbjct: 245 YDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKF 304
Query: 249 GFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSV 308
LP L LD++ NP+L++ F L ++ L L+ L L + + LP LQ V
Sbjct: 305 ALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEV 364
Query: 309 SV-GQDVRCRRLVR 321
+ G +RC ++R
Sbjct: 365 GLHGNPIRCDCVIR 378
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 95.9 bits (237), Expect = 5e-20
Identities = 99/314 (31%), Positives = 143/314 (45%), Gaps = 29/314 (9%)
Query: 4 PLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHL 63
PLLLLLA+ + C GCQC V C+ +P +P DT L
Sbjct: 10 PLLLLLALGPG--VQGCPSGCQCS----------QPQTVFCTARQGTTVPRDVPPDTVGL 57
Query: 64 DLSSNRLEMVNESVLAG-PGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
+ N + M++ AG PG L LDLS N + S+ F L L +LDL+ N L
Sbjct: 58 YVFENGITMLDAGSFAGLPG---LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHE 114
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
+ E+F L + L N++R + AF T R L + L N + L P L
Sbjct: 115 ITNETFRGLRRLERLYLGKNRIRHIQPGAFDT--LDRLLELKLQDNELRALPP------L 166
Query: 182 PAPTIQSLNLAWNRLHAV-PNLRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASL 239
P + L+L+ N L A+ P + D + L L G L + G F+ L L L ++
Sbjct: 167 RLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDN 226
Query: 240 QRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALL 299
Q E P R L GL L L+GN ++ E +GL++LQELD+S +L LP L
Sbjct: 227 QL--ERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLS 284
Query: 300 LHLPALQSVSVGQD 313
P L+ ++ ++
Sbjct: 285 GLFPRLRLLAAARN 298
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 90.5 bits (223), Expect = 2e-18
Identities = 90/301 (29%), Positives = 125/301 (41%), Gaps = 66/301 (21%)
Query: 4 PLLLLLAVSGAQTT-----RPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPL 58
P+LL LA G+ R C C CE D L RVDCS LG +P + +
Sbjct: 13 PVLLQLATGGSSPRSGVLLRGCPTHCHCEP------DGRMLLRVDCSDLGLSELPSNLSV 66
Query: 59 DTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHN 118
T++LDLS N + + + P LR+LE L L+ N
Sbjct: 67 FTSYLDLSMNNI--------------------------SQLLPNPLPSLRFLEELRLAGN 100
Query: 119 GLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPT 177
LT +P +FT L + L +NQLR V A ++L +D +H VP
Sbjct: 101 ALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANH---ISYVPPSC 157
Query: 178 RAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA 237
+GL + LR+L LD N L I AF L L ++LA
Sbjct: 158 FSGLHS-----------------------LRHLWLDDNALTEIPVQAFRSLSALQAMTLA 194
Query: 238 SLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEA 297
L ++ + F L L VL L N +++ G + F GL SL+ LDL+ NL P A
Sbjct: 195 -LNKIHHIPDYAFGNLSSLVVLHLHNN-RIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA 252
Query: 298 L 298
+
Sbjct: 253 I 253
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 38/183 (20%)
Query: 82 GYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHN 141
G L L L+ ++S+ T ++L L+ LDLS+N L LP+ S L ++L HN
Sbjct: 326 GTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQK-LQKIDLRHN 384
Query: 142 QLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV-P 200
++ E+ V F +L+ +++SLNLAWN++ + P
Sbjct: 385 EIYEIKVDTF------------------QQLL-----------SLRSLNLAWNKIAIIHP 415
Query: 201 N-LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQV 258
N LP L L L N L+ GL GLTHL L L L S P L+V
Sbjct: 416 NAFSTLPSLIKLDLSSNLLSSF---PITGLHGLTHLKLTGNHALQSLISS--ENFPELKV 470
Query: 259 LDL 261
+++
Sbjct: 471 IEM 473
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/249 (27%), Positives = 105/249 (42%), Gaps = 51/249 (20%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L +NR+ + + G +L LDL++N L PTA L L+ L N + +
Sbjct: 215 LHLHNNRIHSLGKKCF--DGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHSNNIRS 271
Query: 123 LPAESFTSSP-LSDVNLSHNQLREVSVSAFTTHSQGRALHV----------DLSH--NLI 169
+P ++F +P L ++ N ++ V SAF + R L + DL+ NL
Sbjct: 272 IPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLE 331
Query: 170 HRLVPHPTRAGLPA------PTIQSLNLAWNRLHAVPNL--------------------- 202
+ + LP P +Q L+L++N L +P+
Sbjct: 332 SLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKV 391
Query: 203 ----RDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQV 258
+ L LR L+L N +A+I P AF+ L L L L+S L +G L GL
Sbjct: 392 DTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSS-NLLSSFPITG---LHGLTH 447
Query: 259 LDLSGNPKL 267
L L+GN L
Sbjct: 448 LKLTGNHAL 456
Score = 35.4 bits (80), Expect = 0.078
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 35 DSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTT---LAGLDL 91
+S +LT S L P + +P + LDLS N LE + P ++ L +DL
Sbjct: 331 ESLTLTGAQISSL-PQTVCNQLP-NLQVLDLSYNLLEDL-------PSFSVCQKLQKIDL 381
Query: 92 SHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVNLSHNQLREVSVS 149
HN + I F +L L SL+L+ N + + +F++ P L ++LS N L ++
Sbjct: 382 RHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPIT 440
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 88.2 bits (217), Expect = 1e-17
Identities = 96/329 (29%), Positives = 138/329 (41%), Gaps = 57/329 (17%)
Query: 1 MPWPLLLL-------LAVSGAQTTRP--CFPGCQCEVETFGLFDSFSLTRVDCSGLGPHI 51
MP PL LL L +G P C C C+ + RVDCSG G
Sbjct: 1 MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDR----------RVDCSGKGLTA 50
Query: 52 MPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLE 111
+P + T LD+S N + + E A + L L L+ N L+ I P A S L+ L+
Sbjct: 51 VPEGLSAFTQALDISMNNITQLPED--AFKNFPFLEELQLAGNDLSFIHPKALSGLKELK 108
Query: 112 SLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIH 170
L L +N L +P+E+ S L + L N + V +F Q R H+ L N +
Sbjct: 109 VLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLR--HLWLDDNSLT 166
Query: 171 RLVPHPTRAGLPAPTIQSLNLAWNRLHAVP-----NLRDLPLRYLSLDGNPLAVIGPGAF 225
+ HP PT+Q+L LA N++ ++P NL L + L L N + + F
Sbjct: 167 EVPVHPLS---NLPTLQALTLALNKISSIPDFAFTNLSSLVV--LHLHNNKIRSLSQHCF 221
Query: 226 AGLGGLTHLSL---------ASLQRLPELAPSGFRE-------------LPGLQVLDLSG 263
GL L L L +++ LP L GF P L+ + L
Sbjct: 222 DGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYD 281
Query: 264 NPKLNWAGAEVFSGLSSLQELDLSGTNLV 292
NP L++ G F LS L L + G ++V
Sbjct: 282 NP-LSFVGNSAFHNLSDLHSLVIRGASMV 309
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/224 (31%), Positives = 111/224 (49%), Gaps = 15/224 (6%)
Query: 89 LDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVNLSHNQLREVS 147
+D S LT++ P S + ++LD+S N +T LP ++F + P L ++ L+ N L +
Sbjct: 41 VDCSGKGLTAV-PEGLSA--FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 97
Query: 148 VSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRD--- 204
A + + + L L +N + + VP GL A +QSL L N + +VP
Sbjct: 98 PKALSGLKELKVL--TLQNNQL-KTVPSEAIRGLSA--LQSLRLDANHITSVPEDSFEGL 152
Query: 205 LPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGN 264
+ LR+L LD N L + + L L L+LA L ++ + F L L VL L N
Sbjct: 153 VQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLA-LNKISSIPDFAFTNLSSLVVLHLHNN 211
Query: 265 PKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSV 308
K+ F GL +L+ LDL+ NL P+A+ LP+L+ +
Sbjct: 212 -KIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKA-LPSLKEL 253
Score = 49.3 bits (116), Expect = 5e-06
Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 180 GLPAPTIQSLNLAWNRLHAVPN--LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSL 236
GL A T Q+L+++ N + +P ++ P L L L GN L+ I P A +GL L L+L
Sbjct: 54 GLSAFT-QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTL 112
Query: 237 ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPE 296
+ Q L + R L LQ L L N + + F GL L+ L L +L +P
Sbjct: 113 QNNQ-LKTVPSEAIRGLSALQSLRLDAN-HITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 170
Query: 297 ALLLHLPALQSVSV 310
L +LP LQ++++
Sbjct: 171 HPLSNLPTLQALTL 184
Score = 47.0 bits (110), Expect = 3e-05
Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Query: 82 GYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSH 140
G L L L+ ++SI + L +LDLS+N + LP SF L +++L
Sbjct: 317 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQR 374
Query: 141 NQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVP 200
NQ+ ++ F R L DLS NLIH + +RA I +L++++N L + P
Sbjct: 375 NQIYQIKEGTFQGLISLRIL--DLSRNLIHEI---HSRAFATLGPITNLDVSFNELTSFP 429
Query: 201 NLRDLPLRYLSLDGN 215
L L L GN
Sbjct: 430 TEGLNGLNQLKLVGN 444
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
+ L N++ + E G +L LDLS NL+ I AF+ L + +LD+S N LT+
Sbjct: 370 ISLQRNQIYQIKEGTFQG--LISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTS 427
Query: 123 LPAE 126
P E
Sbjct: 428 FPTE 431
>gi|193083139 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 87.4 bits (215), Expect = 2e-17
Identities = 96/276 (34%), Positives = 127/276 (46%), Gaps = 51/276 (18%)
Query: 41 RVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGP--GYTTLAGLDLSHNLLTS 98
+V C LG +P +P DT LDLS N+L S+LA P YT L LDLS N ++
Sbjct: 32 KVSCQVLGLLQVPSVLPPDTETLDLSGNQLR----SILASPLGFYTALRHLDLSTNEISF 87
Query: 99 ISPTAFSRLRYLESLDLSHNGL---TALPAESFTSSP-LSDVNLSHNQLREVSVSAFTTH 154
+ P AF L +LE L L+HN L TAL A P ++ ++LS N L
Sbjct: 88 LQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYS--------- 138
Query: 155 SQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVP--NLRDLP-LRYLS 211
L+ RL+ AP++ +L+LA N L + RD+P L L
Sbjct: 139 ------------GLLERLLGE-------APSLHTLSLAENSLTRLTRHTFRDMPALEQLD 179
Query: 212 LDGNPLAVIGPGAFAGLGGLTHLSLA--SLQRLPELAPSGFRELPGLQVLDLSGNPKLNW 269
L N L I GAF GL LTHL+L+ SL + + + L L+VLDLS N +
Sbjct: 180 LHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS------LQQLRVLDLSCNSIEAF 233
Query: 270 AGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPAL 305
A L LDL L+ P+ L LP L
Sbjct: 234 QTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRL 267
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/300 (28%), Positives = 118/300 (39%), Gaps = 69/300 (23%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDL SN L + + A G L L+LS N LT IS + +LR L DLS N + A
Sbjct: 178 LDLHSNVLMDIEDG--AFEGLPRLTHLNLSRNSLTCISDFSLQQLRVL---DLSCNSIEA 232
Query: 123 LPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQ-GRALHVDLSHNLIHR---------- 171
S P ++ L+ LRE + F + R ++++LS+NLI
Sbjct: 233 FQT---ASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKG 289
Query: 172 -------------LVPHPTRAGLPAPTIQSLNLAWNRLHAVPN----------------- 201
P +G P + +L+L++N + +P+
Sbjct: 290 IHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRN 349
Query: 202 ---------LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFR 251
L LP L L L N L + GA A LG L L L L +L P F
Sbjct: 350 CLRTFEARRLGSLPCLMLLDLSHNALETLELGARA-LGSLRTLLLQG-NALRDLPPYTFA 407
Query: 252 ELPGLQVLDLSGN--------PKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLP 303
L LQ L+L GN + +G FSG++SL+ L L + L LH P
Sbjct: 408 NLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP 467
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 184 PTIQSLNLAWNRLHAV---PNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLAS-- 238
P ++L+L+ N+L ++ P LR+L L N ++ + PGAF L L HLSLA
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 239 LQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEAL 298
L L+ G LP + LDLSGN + + SL L L+ +L L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 299 LLHLPALQSVSVGQDV 314
+PAL+ + + +V
Sbjct: 169 FRDMPALEQLDLHSNV 184
Score = 53.1 bits (126), Expect = 4e-07
Identities = 80/287 (27%), Positives = 115/287 (40%), Gaps = 35/287 (12%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
+LDLS N +E++ +S L T+L L+LS N L + L L LDLSHN L
Sbjct: 319 NLDLSYNEIELIPDSFLEH--LTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALE 376
Query: 122 ALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L + L + L N LR++ F + + L++ + P +G
Sbjct: 377 TLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGC 436
Query: 182 PA----PTIQSLNLAWNRLHAV--PNLRDLPLRYLSLDGNPLAVIGPGAFAGL------- 228
A +++SL+L N + + PL L L NP + GA GL
Sbjct: 437 VAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVL 496
Query: 229 ----GGLTHLSL-----ASLQRLPELAPSGFRELP------GLQVLDLSGNPKLNWAGAE 273
GL L + L+RL LA + LP L+VLDL N G+
Sbjct: 497 ALQGNGLMVLQVDLPCFICLKRL-NLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSA 555
Query: 274 VFSGLSSLQELDLSGTNLVPLPEALL---LHLPALQSVSVGQDVRCR 317
+ +SL+ L L G L L LH + V QD+ CR
Sbjct: 556 MGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRV-DVDATQDLICR 601
Score = 52.4 bits (124), Expect = 6e-07
Identities = 79/250 (31%), Positives = 105/250 (42%), Gaps = 39/250 (15%)
Query: 79 AGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVN 137
+G + L LDLS+N + I + L L L+LS N L A S P L ++
Sbjct: 310 SGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLD 369
Query: 138 LSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLH 197
LSHN L + + A + G + L N + L P+ T A L ++Q LNL NR
Sbjct: 370 LSHNALETLELGA---RALGSLRTLLLQGNALRDLPPY-TFANL--ASLQRLNLQGNR-- 421
Query: 198 AVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHL-SLASLQRLPELAPSGFRELPGL 256
+S G P GP G+T L SL+ + EL +G L
Sbjct: 422 ------------VSPCGGP-DEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPL 468
Query: 257 QVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNL----VPLP-----------EALLLH 301
LDLS NP L A + +SL+ L L G L V LP E L H
Sbjct: 469 TELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSH 528
Query: 302 LPA-LQSVSV 310
LPA Q+VS+
Sbjct: 529 LPAWTQAVSL 538
>gi|5031707 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 87.4 bits (215), Expect = 2e-17
Identities = 96/276 (34%), Positives = 127/276 (46%), Gaps = 51/276 (18%)
Query: 41 RVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGP--GYTTLAGLDLSHNLLTS 98
+V C LG +P +P DT LDLS N+L S+LA P YT L LDLS N ++
Sbjct: 32 KVSCQVLGLLQVPSVLPPDTETLDLSGNQLR----SILASPLGFYTALRHLDLSTNEISF 87
Query: 99 ISPTAFSRLRYLESLDLSHNGL---TALPAESFTSSP-LSDVNLSHNQLREVSVSAFTTH 154
+ P AF L +LE L L+HN L TAL A P ++ ++LS N L
Sbjct: 88 LQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYS--------- 138
Query: 155 SQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVP--NLRDLP-LRYLS 211
L+ RL+ AP++ +L+LA N L + RD+P L L
Sbjct: 139 ------------GLLERLLGE-------APSLHTLSLAENSLTRLTRHTFRDMPALEQLD 179
Query: 212 LDGNPLAVIGPGAFAGLGGLTHLSLA--SLQRLPELAPSGFRELPGLQVLDLSGNPKLNW 269
L N L I GAF GL LTHL+L+ SL + + + L L+VLDLS N +
Sbjct: 180 LHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS------LQQLRVLDLSCNSIEAF 233
Query: 270 AGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPAL 305
A L LDL L+ P+ L LP L
Sbjct: 234 QTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRL 267
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/300 (28%), Positives = 118/300 (39%), Gaps = 69/300 (23%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDL SN L + + A G L L+LS N LT IS + +LR L DLS N + A
Sbjct: 178 LDLHSNVLMDIEDG--AFEGLPRLTHLNLSRNSLTCISDFSLQQLRVL---DLSCNSIEA 232
Query: 123 LPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQ-GRALHVDLSHNLIHR---------- 171
S P ++ L+ LRE + F + R ++++LS+NLI
Sbjct: 233 FQT---ASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKG 289
Query: 172 -------------LVPHPTRAGLPAPTIQSLNLAWNRLHAVPN----------------- 201
P +G P + +L+L++N + +P+
Sbjct: 290 IHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRN 349
Query: 202 ---------LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFR 251
L LP L L L N L + GA A LG L L L L +L P F
Sbjct: 350 CLRTFEARRLGSLPCLMLLDLSHNALETLELGARA-LGSLRTLLLQG-NALRDLPPYTFA 407
Query: 252 ELPGLQVLDLSGN--------PKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLP 303
L LQ L+L GN + +G FSG++SL+ L L + L LH P
Sbjct: 408 NLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP 467
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 184 PTIQSLNLAWNRLHAV---PNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLAS-- 238
P ++L+L+ N+L ++ P LR+L L N ++ + PGAF L L HLSLA
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 239 LQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEAL 298
L L+ G LP + LDLSGN + + SL L L+ +L L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 299 LLHLPALQSVSVGQDV 314
+PAL+ + + +V
Sbjct: 169 FRDMPALEQLDLHSNV 184
Score = 53.1 bits (126), Expect = 4e-07
Identities = 80/287 (27%), Positives = 115/287 (40%), Gaps = 35/287 (12%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
+LDLS N +E++ +S L T+L L+LS N L + L L LDLSHN L
Sbjct: 319 NLDLSYNEIELIPDSFLEH--LTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALE 376
Query: 122 ALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L + L + L N LR++ F + + L++ + P +G
Sbjct: 377 TLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGC 436
Query: 182 PA----PTIQSLNLAWNRLHAV--PNLRDLPLRYLSLDGNPLAVIGPGAFAGL------- 228
A +++SL+L N + + PL L L NP + GA GL
Sbjct: 437 VAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVL 496
Query: 229 ----GGLTHLSL-----ASLQRLPELAPSGFRELP------GLQVLDLSGNPKLNWAGAE 273
GL L + L+RL LA + LP L+VLDL N G+
Sbjct: 497 ALQGNGLMVLQVDLPCFICLKRL-NLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSA 555
Query: 274 VFSGLSSLQELDLSGTNLVPLPEALL---LHLPALQSVSVGQDVRCR 317
+ +SL+ L L G L L LH + V QD+ CR
Sbjct: 556 MGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRV-DVDATQDLICR 601
Score = 52.4 bits (124), Expect = 6e-07
Identities = 79/250 (31%), Positives = 105/250 (42%), Gaps = 39/250 (15%)
Query: 79 AGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVN 137
+G + L LDLS+N + I + L L L+LS N L A S P L ++
Sbjct: 310 SGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLD 369
Query: 138 LSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLH 197
LSHN L + + A + G + L N + L P+ T A L ++Q LNL NR
Sbjct: 370 LSHNALETLELGA---RALGSLRTLLLQGNALRDLPPY-TFANL--ASLQRLNLQGNR-- 421
Query: 198 AVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHL-SLASLQRLPELAPSGFRELPGL 256
+S G P GP G+T L SL+ + EL +G L
Sbjct: 422 ------------VSPCGGP-DEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPL 468
Query: 257 QVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNL----VPLP-----------EALLLH 301
LDLS NP L A + +SL+ L L G L V LP E L H
Sbjct: 469 TELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSH 528
Query: 302 LPA-LQSVSV 310
LPA Q+VS+
Sbjct: 529 LPAWTQAVSL 538
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 87.0 bits (214), Expect = 2e-17
Identities = 86/348 (24%), Positives = 147/348 (42%), Gaps = 53/348 (15%)
Query: 24 CQCEVETFGLFDSFSL--TRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGP 81
C CE+ + S + + VDC+ LG P +P +T L L +N + + S
Sbjct: 33 CTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST---D 89
Query: 82 GYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSH 140
L GLDLS N L+S++ ++ L S+ L N LT LP + + S L ++ ++H
Sbjct: 90 FPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINH 149
Query: 141 NQLREVSVSAFTTHSQGRALHVD----------------------LSHNLIHR------- 171
N L +S AF LH++ + N I R
Sbjct: 150 NLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFK 209
Query: 172 --------------LVPHPTRAGLPAPTIQSLNLAWNRLHAVPNL---RDLPLRYLSLDG 214
L P A + ++S++ NRL VP++ + + L++L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 215 NPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEV 274
NP+ I G F+ + L L + ++ L + LP L+ ++ + NP+L++
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 275 FSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSV-GQDVRCRRLVR 321
F L L+ L L+ L L + LP L+ +S+ +RC ++R
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIR 377
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 87.0 bits (214), Expect = 2e-17
Identities = 86/348 (24%), Positives = 147/348 (42%), Gaps = 53/348 (15%)
Query: 24 CQCEVETFGLFDSFSL--TRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGP 81
C CE+ + S + + VDC+ LG P +P +T L L +N + + S
Sbjct: 33 CTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST---D 89
Query: 82 GYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSH 140
L GLDLS N L+S++ ++ L S+ L N LT LP + + S L ++ ++H
Sbjct: 90 FPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINH 149
Query: 141 NQLREVSVSAFTTHSQGRALHVD----------------------LSHNLIHR------- 171
N L +S AF LH++ + N I R
Sbjct: 150 NLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFK 209
Query: 172 --------------LVPHPTRAGLPAPTIQSLNLAWNRLHAVPNL---RDLPLRYLSLDG 214
L P A + ++S++ NRL VP++ + + L++L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 215 NPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEV 274
NP+ I G F+ + L L + ++ L + LP L+ ++ + NP+L++
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 275 FSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSV-GQDVRCRRLVR 321
F L L+ L L+ L L + LP L+ +S+ +RC ++R
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIR 377
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 87.0 bits (214), Expect = 2e-17
Identities = 86/348 (24%), Positives = 147/348 (42%), Gaps = 53/348 (15%)
Query: 24 CQCEVETFGLFDSFSL--TRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGP 81
C CE+ + S + + VDC+ LG P +P +T L L +N + + S
Sbjct: 33 CTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST---D 89
Query: 82 GYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSH 140
L GLDLS N L+S++ ++ L S+ L N LT LP + + S L ++ ++H
Sbjct: 90 FPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINH 149
Query: 141 NQLREVSVSAFTTHSQGRALHVD----------------------LSHNLIHR------- 171
N L +S AF LH++ + N I R
Sbjct: 150 NLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFK 209
Query: 172 --------------LVPHPTRAGLPAPTIQSLNLAWNRLHAVPNL---RDLPLRYLSLDG 214
L P A + ++S++ NRL VP++ + + L++L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 215 NPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEV 274
NP+ I G F+ + L L + ++ L + LP L+ ++ + NP+L++
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 275 FSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSV-GQDVRCRRLVR 321
F L L+ L L+ L L + LP L+ +S+ +RC ++R
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIR 377
>gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens]
Length = 347
Score = 84.7 bits (208), Expect = 1e-16
Identities = 100/300 (33%), Positives = 132/300 (44%), Gaps = 51/300 (17%)
Query: 5 LLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLD 64
LLLLLA S T C+V F S + + C P +P +P DT HL
Sbjct: 25 LLLLLAASAWGVT---LSPKDCQV-----FRSDHGSSISCQP--PAEIPGYLPADTVHLA 74
Query: 65 LSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALP 124
+ L + ++L G + L L LS N L S+SP + L LDL+ N LT LP
Sbjct: 75 VEFFNLTHLPANLLQGA--SKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 125 AESF-TSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPA 183
F S+ L + L NQL + VS H H+DLS N + +L P GL A
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWL--HGLKALGHLDLSGNRLRKLPP-----GLLA 185
Query: 184 --PTIQSLNLAWNRLHAVPN--LRD-LPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLAS 238
+++L+L N+L +P LR L L L L+GN L V+G
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLL------------- 232
Query: 239 LQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEAL 298
LP+ P L+ L L+GN KL A F GL L LDLS +L +PE L
Sbjct: 233 ---LPQ---------PDLRYLFLNGN-KLARVAAGAFQGLRQLDMLDLSNNSLASVPEGL 279
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 83.6 bits (205), Expect = 2e-16
Identities = 97/300 (32%), Positives = 135/300 (45%), Gaps = 46/300 (15%)
Query: 42 VDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTS--I 99
VDC GL + P I HL L +N+L+ + + L+ + L L+L +NL++S +
Sbjct: 56 VDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELS--RLSGLRTLNLHNNLISSEGL 113
Query: 100 SPTAFSRLRYLESLDLSHNG---LTALPAESFT-SSPLSDVNLSHNQLREVSVSAFTTHS 155
AF L L+ L ++HN ++ +P + + + L ++ L HNQL + + A T
Sbjct: 114 PDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSK 173
Query: 156 QGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLR---DLPLRYLSL 212
++DLSHN + VP AGLP T+ L+L NR+ V R LRYL L
Sbjct: 174 LHSLEYLDLSHNQL-TTVP----AGLPR-TLAILHLGRNRIRQVEAARLHGARGLRYLLL 227
Query: 213 DGNPLAVIG--PGAFAGLGGL--THLSLASLQRLPELAPSGFREL--------------- 253
N L G GA L GL HL L R+P P R L
Sbjct: 228 QHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDL 287
Query: 254 ---PGLQVLDLSGNPKLNWAGAEV----FSGLSSLQELDLSGTNLVPLPEALLLHLPALQ 306
PGL L+L+ N A A V F L +L+ LDL+G L LP L L LQ
Sbjct: 288 VATPGLTELNLAYN---RLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
Score = 73.2 bits (178), Expect = 3e-13
Identities = 76/232 (32%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 84 TTLAGLDLSHNLLTS--ISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHN 141
T L L L HN LT + T FS+L LE LDLSHN LT +PA L+ ++L N
Sbjct: 149 TQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG--LPRTLAILHLGRN 206
Query: 142 QLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPN 201
++R+ V A H ++ L HN + P A P + +L+L N L VP
Sbjct: 207 RIRQ--VEAARLHGARGLRYLLLQHNQLGS-SGLPAGALRPLRGLHTLHLYGNGLDRVPP 263
Query: 202 LRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRL--PELAPSGFRELPGLQVL 259
LR L L N +A +G GLT L+LA RL + FR L L+ L
Sbjct: 264 ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLA-YNRLASARVHHRAFRRLRALRSL 322
Query: 260 DLSGNP--------------------KLNWAGAEVFSGLSSLQELDLSGTNL 291
DL+GN +L E +GL L+EL L+ L
Sbjct: 323 DLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 374
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/163 (31%), Positives = 68/163 (41%), Gaps = 29/163 (17%)
Query: 46 GLGPHIMPVPIPLDTAHLDLSSNRLEMVN-ESVLAGPGYTTLAGLDLSHNLLTS--ISPT 102
G G +P +P L L N + + ++A PG T L +L++N L S +
Sbjct: 255 GNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTEL---NLAYNRLASARVHHR 311
Query: 103 AFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHV 162
AF RLR L SLDL+ N LT LP T L + L NQLR + Q R L
Sbjct: 312 AFRRLRALRSLDLAGNQLTRLPMGLPTG--LRTLQLQRNQLRMLEPEPLAGLDQLREL-- 367
Query: 163 DLSHNLI-------------------HRLVPHPTRAGLPAPTI 186
L+HN + HRLV H P+P +
Sbjct: 368 SLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCL 410
Score = 28.9 bits (63), Expect = 7.3
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 38 SLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLT 97
+L +D +G +P+ +P L L N+L M+ LA G L L L+HN L
Sbjct: 318 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLA--GLDQLRELSLAHNRLR 375
Query: 98 --SISPTAFSRLRYLE 111
I P + L+ L+
Sbjct: 376 VGDIGPGTWHELQALQ 391
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 82.4 bits (202), Expect = 6e-16
Identities = 78/269 (28%), Positives = 123/269 (45%), Gaps = 45/269 (16%)
Query: 20 CFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLA 79
C GCQC V CS LG +P IP DT LDL +N+++ + E+
Sbjct: 75 CPFGCQCYSRV-----------VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDF- 122
Query: 80 GPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLS 139
G T+L GL L++N LT I P AF + L L LSHN L+ +P L+++ +
Sbjct: 123 -KGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN--LPKSLAELRIH 179
Query: 140 HNQLREVSVSAFTTHSQGRALHV-DLSHN----------------LIHRLVPHPTRAGLP 182
N+++++ F + ALHV ++S N + H + +P
Sbjct: 180 ENKVKKIQKDTFKGMN---ALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVP 236
Query: 183 ---APTIQSLNLAWNRLHAVPNLRDL----PLRYLSLDGNPLAVIGPGAFAGLGGLTHLS 235
PT+ L+L +N++ V L D L+ L L N + I G+ A + + +
Sbjct: 237 KGLPPTLLELHLDYNKISTV-ELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIH 295
Query: 236 LASLQRLPELAPSGFRELPGLQVLDLSGN 264
L + +L ++ PSG EL LQ++ L N
Sbjct: 296 LEN-NKLKKI-PSGLPELKYLQIIFLHSN 322
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 82.4 bits (202), Expect = 6e-16
Identities = 83/262 (31%), Positives = 120/262 (45%), Gaps = 11/262 (4%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L N L +++++ L L L+ N L + + F+ L L+ LDLS N LT
Sbjct: 127 LFLDHNALRGIDQNMFQK--LVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 123 LPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLP 182
LP + + L H+ R VS+ + +S G + N I + P A
Sbjct: 185 LPKGLLGAQAKLERLLLHSN-RLVSLDSGLLNSLGALTELQFHRNHIRSIAPG---AFDR 240
Query: 183 APTIQSLNLAWNRLHAVPN---LRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASL 239
P + SL L+ N L +P+ L L L+L NPLA + F +GGL L L
Sbjct: 241 LPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRT 300
Query: 240 QRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALL 299
Q L L + FR L L+ L ++ +P+L+ F GL LQ L L L LP+ LL
Sbjct: 301 Q-LRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLL 359
Query: 300 LHLPALQSVSVGQDVRCRRLVR 321
L L+ VS+ ++ R R L R
Sbjct: 360 RGLGKLRQVSLRRN-RLRALPR 380
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L SN L + + +L G G L + L N L ++ F L LES+ L HN L
Sbjct: 344 LALHSNGLTALPDGLLRGLG--KLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLET 401
Query: 123 LPAESFTSSP-LSDVNLSHNQLR 144
LP + F + P L++V L HN R
Sbjct: 402 LPGDVFGALPRLTEVLLGHNSWR 424
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 82.4 bits (202), Expect = 6e-16
Identities = 96/313 (30%), Positives = 130/313 (41%), Gaps = 44/313 (14%)
Query: 1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT 60
+P +LLLLA + + C C C+ S V C +P IP T
Sbjct: 14 LPLLVLLLLAPARQAAAQRCPQACICDN---------SRRHVACRYQNLTEVPDAIPELT 64
Query: 61 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL 120
LDL N L+++ + G + T LDL H + ++ AF L L L+L+ N L
Sbjct: 65 QRLDLQGNLLKVIPAAAFQGVPHLT--HLDLRHCEVELVAEGAFRGLGRLLLLNLASNHL 122
Query: 121 TALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRA 179
LP E+ L + L N L E+ F + G ++L+HN +
Sbjct: 123 RELPQEALDGLGSLRRLELEGNALEELRPGTF--GALGALATLNLAHNAL---------V 171
Query: 180 GLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSL--A 237
LPA Q L L +R+L L N L+V+ P A AGL L LSL
Sbjct: 172 YLPAMAFQGL---------------LRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHN 216
Query: 238 SLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEA 297
LQ LP S R GL L+L NP L +AG E L L+EL L G L L
Sbjct: 217 ELQALPGPVLSQAR---GLARLELGHNP-LTYAGEEDGLALPGLRELLLDGGALQALGPR 272
Query: 298 LLLHLPALQSVSV 310
H P L ++ +
Sbjct: 273 AFAHCPRLHTLDL 285
Score = 81.6 bits (200), Expect = 9e-16
Identities = 108/367 (29%), Positives = 144/367 (39%), Gaps = 52/367 (14%)
Query: 19 PCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVL 78
PC C C E+ C G G +P P DT LDL N V +
Sbjct: 395 PCPRACVCVPES---------RHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAF 445
Query: 79 AGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVN 137
G G+ L L L H + + A + L L L LS N L L A + +P L +
Sbjct: 446 PGLGH--LVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLY 503
Query: 138 LSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVP-----------------HPTRAG 180
L N+ +V +A +LH L N + RL P T
Sbjct: 504 LERNRFLQVPGAALRALPSLFSLH--LQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVS 561
Query: 181 L----PAPTIQSLNLAWNRLHAVPN--LRDLP-LRYLSLDGNPLAVIGPGAFAGLG-GLT 232
L PA ++ L+L N+L VP L LP L L L GNPL + GAF +G L
Sbjct: 562 LGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQ 621
Query: 233 HLSLASLQRLPELAPSGFREL-PGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGT-- 289
HL L S L ++ P F L PGLQ L L N LS L+ +DLS
Sbjct: 622 HLFLNS-SGLEQICPGAFSGLGPGLQSLHLQKN---QLRALPALPSLSQLELIDLSSNPF 677
Query: 290 ----NLVPLPEALL-LHLPALQSVSVGQDVRCRRL-VREGTYPRRPGSSPKVALHCVDTR 343
L+PL L L+L + + + R +R+ + PG + + A +R
Sbjct: 678 HCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAARKAKRTPASR 737
Query: 344 DSAARGP 350
SA R P
Sbjct: 738 PSARRTP 744
Score = 67.8 bits (164), Expect = 1e-11
Identities = 69/207 (33%), Positives = 87/207 (42%), Gaps = 38/207 (18%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L+L+SN L + + L G G +L L+L N L + P F L L +L+L+HN L
Sbjct: 115 LNLASNHLRELPQEALDGLG--SLRRLELEGNALEELRPGTFGALGALATLNLAHNALVY 172
Query: 123 LPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQG--RALHVDLSHNLIHRLVPHPTRAG 180
LPA +F QG R + LSHN + L P AG
Sbjct: 173 LPAMAF---------------------------QGLLRVRWLRLSHNALSVLAPE-ALAG 204
Query: 181 LPAPTIQSLNLAWNRLHAVPN---LRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA 237
LPA ++ L+L N L A+P + L L L NPL G L GL L L
Sbjct: 205 LPA--LRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLD 262
Query: 238 SLQRLPELAPSGFRELPGLQVLDLSGN 264
L L P F P L LDL GN
Sbjct: 263 G-GALQALGPRAFAHCPRLHTLDLRGN 288
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 11/162 (6%)
Query: 161 HVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV---PNLRDLP------LRYLS 211
HV L L+ L+ P R Q+ +R H NL ++P + L
Sbjct: 9 HVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLD 68
Query: 212 LDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAG 271
L GN L VI AF G+ LTHL L + + +A FR L L +L+L+ N L
Sbjct: 69 LQGNLLKVIPAAAFQGVPHLTHLDLRHCE-VELVAEGAFRGLGRLLLLNLASN-HLRELP 126
Query: 272 AEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQD 313
E GL SL+ L+L G L L L AL ++++ +
Sbjct: 127 QEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN 168
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 81.6 bits (200), Expect = 9e-16
Identities = 91/299 (30%), Positives = 131/299 (43%), Gaps = 38/299 (12%)
Query: 44 CSGLGPHIMPV-PIPLDTAHLD--LSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSIS 100
C L P PV P D H L +NR V + P + L N +T+I+
Sbjct: 16 CLALPPLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNIT 75
Query: 101 PTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRA 159
F RL L LDL +N + +L ++F S L ++ L +N L+ ++ + R
Sbjct: 76 AFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRI 135
Query: 160 LHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLR---YLSLDGNP 216
L+ + N I RL + GL + + L L N L A+P+ PL YL L+ N
Sbjct: 136 LYAN--GNEISRL-SRGSFEGLES--LVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 190
Query: 217 LAVIGPGAFAGLGGLTHLSLA-------------------------SLQRLPELAPSGFR 251
+ +G AFA LG L L+L+ S L L P F+
Sbjct: 191 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQ 250
Query: 252 ELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSV 310
LP L +L L GN +L E F GL +L+EL L G L LP ALL L +L+++ +
Sbjct: 251 HLPRLGLLSLRGN-QLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDL 308
Score = 58.9 bits (141), Expect = 7e-09
Identities = 69/208 (33%), Positives = 91/208 (43%), Gaps = 14/208 (6%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L N L + ++V A G L L L N + + AF++L L L+LS N L
Sbjct: 160 LRLDGNALGALPDAVFAPLG--NLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQP 217
Query: 123 LPAESFTSSPL---SDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRA 179
+ T +PL S + LS N L+ + F H L + L N + L P
Sbjct: 218 SLRHAATFAPLRSLSSLILSANNLQHLGPRIFQ-HLPRLGL-LSLRGNQLTHLAPEAFW- 274
Query: 180 GLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLS---LDGNPLAVIGPGAFAGLGGLTHLSL 236
GL A ++ L L NRL +P PL L L GN L+ + P F LG L LSL
Sbjct: 275 GLEA--LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSL 332
Query: 237 ASLQRLPELAPSGFRELPGLQVLDLSGN 264
+ L L+ F P L LDL GN
Sbjct: 333 RN-NALSALSGDIFAASPALYRLDLDGN 359
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 81.3 bits (199), Expect = 1e-15
Identities = 87/306 (28%), Positives = 126/306 (41%), Gaps = 43/306 (14%)
Query: 10 AVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNR 69
A G+ C C C S +RV C+ +P IP++T +L+L N
Sbjct: 47 AGGGSPPATSCPVACSC---------SNQASRVICTRRDLAEVPASIPVNTRYLNLQENG 97
Query: 70 LEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFT 129
++++ + + L LS NL+ I AF+ L L +L+L N LT +P ++F
Sbjct: 98 IQVIRTDTFKHLRHLEI--LQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFE 155
Query: 130 -SSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQS 188
S L ++ L +N + + AF R L DL + GL ++
Sbjct: 156 YLSKLRELWLRNNPIESIPSYAFNRVPSLRRL--DLGELKRLEYISEAAFEGL--VNLRY 211
Query: 189 LNLAWNRLHAVPNLRDL-PLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAP 247
LNL L +PNL L L L L GN L +I PG+F GL L L L
Sbjct: 212 LNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMH--------- 262
Query: 248 SGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQS 307
QV + N F L SL+EL+LS NL+ LP L L L+
Sbjct: 263 --------AQVATIERN---------AFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLER 305
Query: 308 VSVGQD 313
V + +
Sbjct: 306 VHLNHN 311
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 80.9 bits (198), Expect = 2e-15
Identities = 79/294 (26%), Positives = 136/294 (46%), Gaps = 27/294 (9%)
Query: 31 FGLFDSFSLTR-------VDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY 83
FG+ + S T+ DCS L +P +P + L+L+ N+L + + Y
Sbjct: 17 FGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTR--Y 74
Query: 84 TTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFT-SSPLSDVNLSHNQ 142
+ L LD+ N ++ + P +L L+ L+L HN L+ L ++F + L++++L N
Sbjct: 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
Query: 143 LREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG--LPAPTIQSLNLAWNRLHAVP 200
++++ + F Q + +DLSHN + T+ G + +Q L L+ N++ A+
Sbjct: 135 IQKIKNNPFV--KQKNLITLDLSHNGL-----SSTKLGTQVQLENLQELLLSNNKIQALK 187
Query: 201 N-----LRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPG 255
+ + L+ L L N + PG F +G L L L ++Q P L EL
Sbjct: 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
Query: 256 LQVLDLS-GNPKLNWAGAEVFSGL--SSLQELDLSGTNLVPLPEALLLHLPALQ 306
+ +LS N +L+ F GL ++L LDLS NL + LP L+
Sbjct: 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
Score = 47.0 bits (110), Expect = 3e-05
Identities = 67/286 (23%), Positives = 121/286 (42%), Gaps = 44/286 (15%)
Query: 43 DCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPT 102
D G+ ++ I L L S L + ++ L L+L+ N ++ I
Sbjct: 366 DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESD 425
Query: 103 AFSRLRYLESLDLSHN--GLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRAL 160
AFS L +LE LDL N G E + ++ LS+N+ +++ ++F AL
Sbjct: 426 AFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF-------AL 478
Query: 161 HVDLSHNLIHRL-VPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRD------LPLRYLSLD 213
L ++ R+ + + + P +++L + + + N+ D L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 214 GNPLAVIGPGAFAG-----LGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLN 268
N LA + A G L GL+HL + +L+ +GF E+P
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLES------NGFDEIP-------------- 578
Query: 269 WAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDV 314
EVF L L+ +DL NL LP ++ + +L+S+++ +++
Sbjct: 579 ---VEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Score = 46.6 bits (109), Expect = 3e-05
Identities = 73/274 (26%), Positives = 112/274 (40%), Gaps = 58/274 (21%)
Query: 22 PGCQCEV-ETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAH-----LDLSSNRLEMVNE 75
PGC + FGLF L V LGP + + L+ A+ L LS+++L +
Sbjct: 214 PGCFHAIGRLFGLF----LNNVQ---LGPSLTE-KLCLELANTSIRNLSLSNSQLSTTSN 265
Query: 76 SVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSD 135
+ G +T L LDLS+N L + +F+ L LE L +N + L F+ S
Sbjct: 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL----FSHSLHGL 321
Query: 136 VNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNR 195
N+ + L+ +FT S A P I + W +
Sbjct: 322 FNVRYLNLKR----SFTKQSISLA----------------------SLPKIDDFSFQWLK 355
Query: 196 LHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA-SLQRLPELAPSGFREL- 253
L +L+++ N + I F GL L +LSL+ S L L F L
Sbjct: 356 C----------LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
Query: 254 -PGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDL 286
L +L+L+ N K++ ++ FS L L+ LDL
Sbjct: 406 HSPLHILNLTKN-KISKIESDAFSWLGHLEVLDL 438
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSI-------SPTAFSR-LRYLESLD 114
LDLS+N + +N+ +L G L LDL HN L + P F + L +L L+
Sbjct: 511 LDLSNNNIANINDDML--EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 115 LSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLI 169
L NG +P E F L ++L N L + S F ++L +L NLI
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL--NLQKNLI 622
Score = 38.5 bits (88), Expect = 0.009
Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 23/143 (16%)
Query: 89 LDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP---------LSDVNLS 139
LDLS+N + +I+ L LE LDL HN L L + P L +NL
Sbjct: 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
Query: 140 HNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV 199
N E+ V F + + +DL N ++ L P +++SLNL N + +V
Sbjct: 571 SNGFDEIPVEVFKDLFELKI--IDLGLNNLNTL---PASVFNNQVSLKSLNLQKNLITSV 625
Query: 200 P---------NLRDLPLRYLSLD 213
NL +L +R+ D
Sbjct: 626 EKKVFGPAFRNLTELDMRFNPFD 648
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 80.5 bits (197), Expect = 2e-15
Identities = 88/254 (34%), Positives = 113/254 (44%), Gaps = 17/254 (6%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDLS NR+ + E PG L L LSHN + S+ P F L +LE L L HN +
Sbjct: 309 LDLSHNRVAGLLEDTF--PGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 366
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L SF L + L HNQL+EV AF + + +LS N + L P GL
Sbjct: 367 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVM--NLSGNCLRNL-PEQVFRGL 423
Query: 182 PAPTIQSLNLAWN-----RLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSL 236
+ SL+L + R H L LR L L N L I + GL L L L
Sbjct: 424 --GKLHSLHLEGSCLGRIRPHTFTGLSG--LRRLFLKDNGLVGIEEQSLWGLAELLELDL 479
Query: 237 ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPE 296
S Q L L F+ L L+ L LS N +L A+ L LD+S L LP
Sbjct: 480 TSNQ-LTHLPHRLFQGLGKLEYLLLSRN-RLAELPADALGPLQRAFWLDVSHNRLEALPN 537
Query: 297 ALLLHLPALQSVSV 310
+LL L L+ +S+
Sbjct: 538 SLLAPLGRLRYLSL 551
Score = 72.4 bits (176), Expect = 6e-13
Identities = 85/294 (28%), Positives = 126/294 (42%), Gaps = 43/294 (14%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
HL L N+L + A LA L LS+N L+ + F L L L+L N L
Sbjct: 164 HLHLERNQLRSLALGTFAHT--PALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLA 221
Query: 122 ALPAESFTS-------------------------SPLSDVNLSHNQLREVSVSAFTTHSQ 156
LP +F + L +++LS N LR + + F +
Sbjct: 222 VLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPR 281
Query: 157 GRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV-----PNLRDLPLRYLS 211
+ L++D NLI + P A L ++ L+L+ NR+ + P L L LR L
Sbjct: 282 LQKLYLD--RNLIAAVAP---GAFLGLKALRWLDLSHNRVAGLLEDTFPGL--LGLRVLR 334
Query: 212 LDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAG 271
L N +A + P F L L L L R+ +LA F L L+VL L N +L
Sbjct: 335 LSHNAIASLRPRTFKDLHFLEELQLGH-NRIRQLAERSFEGLGQLEVLTLDHN-QLQEVK 392
Query: 272 AEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTY 325
A F GL+++ ++LSG L LPE + L L S+ + + C +R T+
Sbjct: 393 AGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL--EGSCLGRIRPHTF 444
Score = 71.2 bits (173), Expect = 1e-12
Identities = 79/252 (31%), Positives = 110/252 (43%), Gaps = 21/252 (8%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDLS N L + +V L L L NL+ +++P AF L+ L LDLSHN +
Sbjct: 261 LDLSRNALRAIKANVFVQ--LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 318
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALH----VDLSHNLIHRLVPHPT 177
L ++F L + LSHN + + F + LH + L HN I +L
Sbjct: 319 LLEDTFPGLLGLRVLRLSHNAIASLRPRTF------KDLHFLEELQLGHNRIRQLA---E 369
Query: 178 RAGLPAPTIQSLNLAWNRLHAVPNLRDLPL---RYLSLDGNPLAVIGPGAFAGLGGLTHL 234
R+ ++ L L N+L V L L ++L GN L + F GLG L L
Sbjct: 370 RSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSL 429
Query: 235 SLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPL 294
L L + P F L GL+ L L N + ++ GL+ L ELDL+ L L
Sbjct: 430 HLEG-SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW-GLAELLELDLTSNQLTHL 487
Query: 295 PEALLLHLPALQ 306
P L L L+
Sbjct: 488 PHRLFQGLGKLE 499
Score = 61.2 bits (147), Expect = 1e-09
Identities = 72/252 (28%), Positives = 106/252 (42%), Gaps = 62/252 (24%)
Query: 66 SSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPA 125
SS L + + V PG T LD N L+S+ P AF L L L+L L +L
Sbjct: 99 SSRNLTRLPDGV---PGGTQALWLD--GNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEP 153
Query: 126 ESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAP 184
++ L ++L NQLR +++ F P
Sbjct: 154 QALLGLENLCHLHLERNQLRSLALGTFAH-----------------------------TP 184
Query: 185 TIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA--SLQRL 242
+ SL L+ NRL + + G F GLG L L+L SL L
Sbjct: 185 ALASLGLSNNRLSRLED---------------------GLFEGLGSLWDLNLGWNSLAVL 223
Query: 243 PELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHL 302
P+ A FR L L+ L L+GN +L + +FSGL+ L+ELDLS L + + + L
Sbjct: 224 PDAA---FRGLGSLRELVLAGN-RLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQL 279
Query: 303 PALQSVSVGQDV 314
P LQ + + +++
Sbjct: 280 PRLQKLYLDRNL 291
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 80.5 bits (197), Expect = 2e-15
Identities = 88/254 (34%), Positives = 113/254 (44%), Gaps = 17/254 (6%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDLS NR+ + E PG L L LSHN + S+ P F L +LE L L HN +
Sbjct: 271 LDLSHNRVAGLLEDTF--PGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 328
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L SF L + L HNQL+EV AF + + +LS N + L P GL
Sbjct: 329 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVM--NLSGNCLRNL-PEQVFRGL 385
Query: 182 PAPTIQSLNLAWN-----RLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSL 236
+ SL+L + R H L LR L L N L I + GL L L L
Sbjct: 386 --GKLHSLHLEGSCLGRIRPHTFTGLSG--LRRLFLKDNGLVGIEEQSLWGLAELLELDL 441
Query: 237 ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPE 296
S Q L L F+ L L+ L LS N +L A+ L LD+S L LP
Sbjct: 442 TSNQ-LTHLPHRLFQGLGKLEYLLLSRN-RLAELPADALGPLQRAFWLDVSHNRLEALPN 499
Query: 297 ALLLHLPALQSVSV 310
+LL L L+ +S+
Sbjct: 500 SLLAPLGRLRYLSL 513
Score = 72.4 bits (176), Expect = 6e-13
Identities = 85/294 (28%), Positives = 126/294 (42%), Gaps = 43/294 (14%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
HL L N+L + A LA L LS+N L+ + F L L L+L N L
Sbjct: 126 HLHLERNQLRSLALGTFAHT--PALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLA 183
Query: 122 ALPAESFTS-------------------------SPLSDVNLSHNQLREVSVSAFTTHSQ 156
LP +F + L +++LS N LR + + F +
Sbjct: 184 VLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPR 243
Query: 157 GRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV-----PNLRDLPLRYLS 211
+ L++D NLI + P A L ++ L+L+ NR+ + P L L LR L
Sbjct: 244 LQKLYLD--RNLIAAVAP---GAFLGLKALRWLDLSHNRVAGLLEDTFPGL--LGLRVLR 296
Query: 212 LDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAG 271
L N +A + P F L L L L R+ +LA F L L+VL L N +L
Sbjct: 297 LSHNAIASLRPRTFKDLHFLEELQLGH-NRIRQLAERSFEGLGQLEVLTLDHN-QLQEVK 354
Query: 272 AEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTY 325
A F GL+++ ++LSG L LPE + L L S+ + + C +R T+
Sbjct: 355 AGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL--EGSCLGRIRPHTF 406
Score = 71.2 bits (173), Expect = 1e-12
Identities = 79/252 (31%), Positives = 110/252 (43%), Gaps = 21/252 (8%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
LDLS N L + +V L L L NL+ +++P AF L+ L LDLSHN +
Sbjct: 223 LDLSRNALRAIKANVFVQ--LPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALH----VDLSHNLIHRLVPHPT 177
L ++F L + LSHN + + F + LH + L HN I +L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTF------KDLHFLEELQLGHNRIRQLA---E 331
Query: 178 RAGLPAPTIQSLNLAWNRLHAVPNLRDLPL---RYLSLDGNPLAVIGPGAFAGLGGLTHL 234
R+ ++ L L N+L V L L ++L GN L + F GLG L L
Sbjct: 332 RSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSL 391
Query: 235 SLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPL 294
L L + P F L GL+ L L N + ++ GL+ L ELDL+ L L
Sbjct: 392 HLEG-SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW-GLAELLELDLTSNQLTHL 449
Query: 295 PEALLLHLPALQ 306
P L L L+
Sbjct: 450 PHRLFQGLGKLE 461
Score = 61.2 bits (147), Expect = 1e-09
Identities = 72/252 (28%), Positives = 106/252 (42%), Gaps = 62/252 (24%)
Query: 66 SSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPA 125
SS L + + V PG T LD N L+S+ P AF L L L+L L +L
Sbjct: 61 SSRNLTRLPDGV---PGGTQALWLD--GNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEP 115
Query: 126 ESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAP 184
++ L ++L NQLR +++ F P
Sbjct: 116 QALLGLENLCHLHLERNQLRSLALGTFAH-----------------------------TP 146
Query: 185 TIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA--SLQRL 242
+ SL L+ NRL + + G F GLG L L+L SL L
Sbjct: 147 ALASLGLSNNRLSRLED---------------------GLFEGLGSLWDLNLGWNSLAVL 185
Query: 243 PELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHL 302
P+ A FR L L+ L L+GN +L + +FSGL+ L+ELDLS L + + + L
Sbjct: 186 PDAA---FRGLGSLRELVLAGN-RLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQL 241
Query: 303 PALQSVSVGQDV 314
P LQ + + +++
Sbjct: 242 PRLQKLYLDRNL 253
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 80.5 bits (197), Expect = 2e-15
Identities = 86/267 (32%), Positives = 125/267 (46%), Gaps = 13/267 (4%)
Query: 46 GLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFS 105
G GP P P + LS++ E+ S + G A LDLS N LT + P F
Sbjct: 29 GPGPTACPAPCHCQEDGIMLSADCSEL-GLSAVPGDLDPLTAYLDLSMNNLTELQPGLFH 87
Query: 106 RLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDL 164
LR+LE L LS N L+ +P ++F+ L + L +NQL + A ++L +D
Sbjct: 88 HLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDA 147
Query: 165 SHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVP--NLRDLP-LRYLSLDGNPLAVIG 221
NLI LVP + GL +++ L L N L +P L +LP L+ ++L N ++ I
Sbjct: 148 --NLI-SLVPERSFEGL--SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIP 202
Query: 222 PGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSL 281
AF L L L L + R+ L F L L+ LDL+ N + A L L
Sbjct: 203 DYAFQNLTSLVVLHLHN-NRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA--IRTLGRL 259
Query: 282 QELDLSGTNLVPLPEALLLHLPALQSV 308
QEL N+ +PE + P LQ++
Sbjct: 260 QELGFHNNNIKAIPEKAFMGNPLLQTI 286
Score = 70.5 bits (171), Expect = 2e-12
Identities = 99/368 (26%), Positives = 141/368 (38%), Gaps = 76/368 (20%)
Query: 20 CFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLA 79
C C C+ + L DCS LG +P + TA+LDLS N L + +
Sbjct: 35 CPAPCHCQEDGIML-------SADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFH 87
Query: 80 GPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSP-LSDVNL 138
+ L L LS N L+ I AFS L L+ L L +N L +PAE+ P L + L
Sbjct: 88 HLRF--LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 145
Query: 139 SHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHA 198
N + V +F S R L +D + L P RA P +Q++ LA NR+
Sbjct: 146 DANLISLVPERSFEGLSSLRHLWLD-----DNALTEIPVRALNNLPALQAMTLALNRISH 200
Query: 199 VP-----NLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSL------------ASLQR 241
+P NL L + L L N + +G +F GL L L L +L R
Sbjct: 201 IPDYAFQNLTSLVV--LHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGR 258
Query: 242 LPELA----------PSGFRELPGLQVLDLSGNPKLNWAGAEVFS--------------- 276
L EL F P LQ + NP + + G F
Sbjct: 259 LQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNP-IQFVGRSAFQYLPKLHTLSLNGAMD 317
Query: 277 --------GLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDV--------RCRRLV 320
G +SL+ L L+ + LP + LP L+ + + + RC++L
Sbjct: 318 IQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLE 377
Query: 321 REGTYPRR 328
G R
Sbjct: 378 EIGLQHNR 385
Score = 62.4 bits (150), Expect = 6e-10
Identities = 78/257 (30%), Positives = 113/257 (43%), Gaps = 20/257 (7%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L +NR++ + G L LDL++N L P A L L+ L +N + A
Sbjct: 215 LHLHNNRIQHLGTHSFEG--LHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKA 271
Query: 123 LPAESFTSSPL-SDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
+P ++F +PL ++ N ++ V SAF + LH LS N + P G
Sbjct: 272 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPK---LHT-LSLNGAMDIQEFPDLKGT 327
Query: 182 PAPTIQSLNLAWNRLHAVPNLRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ 240
+ I +L A RL + LP LR L L N + + L L LQ
Sbjct: 328 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-----PSLHRCQKLEEIGLQ 382
Query: 241 --RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEA- 297
R+ E+ F +L LQ LDLS N + E FS L SL +LDL+ L LP A
Sbjct: 383 HNRIWEIGADTFSQLSSLQALDLSWNA-IRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAG 441
Query: 298 --LLLHLPALQSVSVGQ 312
L+HL ++++ Q
Sbjct: 442 LGGLMHLKLKGNLALSQ 458
Score = 61.6 bits (148), Expect = 1e-09
Identities = 80/253 (31%), Positives = 115/253 (45%), Gaps = 39/253 (15%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
HL L N L + V A L + L+ N ++ I AF L L L L +N +
Sbjct: 166 HLWLDDNALTEI--PVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 223
Query: 122 ALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG 180
L SF L ++L++N+L+E V+ T GR + +N I + P +A
Sbjct: 224 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTL---GRLQELGFHNNNIKAI---PEKAF 277
Query: 181 LPAPTIQSLNLAWNRLHAVPN--LRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLA 237
+ P +Q+++ N + V + LP L LSL+G + F L G T L +
Sbjct: 278 MGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG----AMDIQEFPDLKGTTSLEIL 333
Query: 238 SLQRLP-ELAPSGF-RELPGLQVLDLSGN-----PKLN---------------WA-GAEV 274
+L R L PSG ++LP L+VL+LS N P L+ W GA+
Sbjct: 334 TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADT 393
Query: 275 FSGLSSLQELDLS 287
FS LSSLQ LDLS
Sbjct: 394 FSQLSSLQALDLS 406
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 80.1 bits (196), Expect = 3e-15
Identities = 81/290 (27%), Positives = 129/290 (44%), Gaps = 27/290 (9%)
Query: 40 TRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSI 99
++V+C+G +P P+P + L + + + +NES + L L + N L+ I
Sbjct: 41 SQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLN--ISALIALRIEKNELSRI 98
Query: 100 SPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGR 158
+P AF L L L L++N L LP F L + LS NQL ++ + F+ S +
Sbjct: 99 TPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLK 158
Query: 159 ALHVDLSH------------------NLIHRLVPH-PTRAGLPAPTIQSLNLAWNRLHAV 199
L + +H NL + H R +Q L L NRL +
Sbjct: 159 ELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDI 218
Query: 200 P-NLRD--LPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGL 256
P D + L+ L+L N + ++ PG F L L L++ + +L PS F +LP L
Sbjct: 219 PMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSN-NHISQLPPSIFMQLPQL 277
Query: 257 QVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQ 306
L L GN L +F + +L+EL L ++ LP+ + +L LQ
Sbjct: 278 NRLTLFGN-SLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQ 326
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/143 (36%), Positives = 74/143 (51%), Gaps = 2/143 (1%)
Query: 171 RLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGG 230
R+V PT A ++Q LN L+ P L L L ++ N L+ I PGAF LG
Sbjct: 49 RIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGS 108
Query: 231 LTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTN 290
L +LSLA+ +L L F+ L L+ L LS N L A FS S+L+EL L G +
Sbjct: 109 LRYLSLAN-NKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAH-FSQCSNLKELQLHGNH 166
Query: 291 LVPLPEALLLHLPALQSVSVGQD 313
L +P+ HL L +++G++
Sbjct: 167 LEYIPDGAFDHLVGLTKLNLGKN 189
Score = 64.7 bits (156), Expect = 1e-10
Identities = 80/281 (28%), Positives = 124/281 (44%), Gaps = 28/281 (9%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
+L L++N+L+++ + G +L L LS N L I P FS+ L+ L L N L
Sbjct: 111 YLSLANNKLQVLPIGLFQG--LDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLE 168
Query: 122 ALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHV------DLSHNL------ 168
+P +F L+ +NL N L +S F + L + D+
Sbjct: 169 YIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVN 228
Query: 169 IHRLVPHPTRAGLPAP-------TIQSLNLAWNRLHAVPN--LRDLP-LRYLSLDGNPLA 218
+ L + GL +P +Q L L+ N + +P LP L L+L GN L
Sbjct: 229 LQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLK 288
Query: 219 VIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGL 278
+ G F + L L L + L + F L LQVL LS N ++++ F+GL
Sbjct: 289 ELSLGIFGPMPNLRELWLYD-NHISSLPDNVFSNLRQLQVLILSRN-QISFISPGAFNGL 346
Query: 279 SSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRL 319
+ L+EL L L L + L LQ++S+ Q+ R R+L
Sbjct: 347 TELRELSLHTNALQDLDGNVFRMLANLQNISL-QNNRLRQL 386
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 80.1 bits (196), Expect = 3e-15
Identities = 81/290 (27%), Positives = 129/290 (44%), Gaps = 27/290 (9%)
Query: 40 TRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSI 99
++V+C+G +P P+P + L + + + +NES + L L + N L+ I
Sbjct: 35 SQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLN--ISALIALRIEKNELSRI 92
Query: 100 SPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGR 158
+P AF L L L L++N L LP F L + LS NQL ++ + F+ S +
Sbjct: 93 TPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLK 152
Query: 159 ALHVDLSH------------------NLIHRLVPH-PTRAGLPAPTIQSLNLAWNRLHAV 199
L + +H NL + H R +Q L L NRL +
Sbjct: 153 ELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDI 212
Query: 200 P-NLRD--LPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGL 256
P D + L+ L+L N + ++ PG F L L L++ + +L PS F +LP L
Sbjct: 213 PMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSN-NHISQLPPSIFMQLPQL 271
Query: 257 QVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQ 306
L L GN L +F + +L+EL L ++ LP+ + +L LQ
Sbjct: 272 NRLTLFGN-SLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQ 320
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/143 (36%), Positives = 74/143 (51%), Gaps = 2/143 (1%)
Query: 171 RLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGG 230
R+V PT A ++Q LN L+ P L L L ++ N L+ I PGAF LG
Sbjct: 43 RIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGS 102
Query: 231 LTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTN 290
L +LSLA+ +L L F+ L L+ L LS N L A FS S+L+EL L G +
Sbjct: 103 LRYLSLAN-NKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAH-FSQCSNLKELQLHGNH 160
Query: 291 LVPLPEALLLHLPALQSVSVGQD 313
L +P+ HL L +++G++
Sbjct: 161 LEYIPDGAFDHLVGLTKLNLGKN 183
Score = 64.7 bits (156), Expect = 1e-10
Identities = 80/281 (28%), Positives = 124/281 (44%), Gaps = 28/281 (9%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
+L L++N+L+++ + G +L L LS N L I P FS+ L+ L L N L
Sbjct: 105 YLSLANNKLQVLPIGLFQG--LDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLE 162
Query: 122 ALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHV------DLSHNL------ 168
+P +F L+ +NL N L +S F + L + D+
Sbjct: 163 YIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVN 222
Query: 169 IHRLVPHPTRAGLPAP-------TIQSLNLAWNRLHAVPN--LRDLP-LRYLSLDGNPLA 218
+ L + GL +P +Q L L+ N + +P LP L L+L GN L
Sbjct: 223 LQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLK 282
Query: 219 VIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGL 278
+ G F + L L L + L + F L LQVL LS N ++++ F+GL
Sbjct: 283 ELSLGIFGPMPNLRELWLYD-NHISSLPDNVFSNLRQLQVLILSRN-QISFISPGAFNGL 340
Query: 279 SSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRL 319
+ L+EL L L L + L LQ++S+ Q+ R R+L
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISL-QNNRLRQL 380
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 78.6 bits (192), Expect = 8e-15
Identities = 83/264 (31%), Positives = 113/264 (42%), Gaps = 32/264 (12%)
Query: 52 MPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTS--ISPTAFSRLRY 109
+P +P L L +N + V L+ T L L L HN LT + T FS+L
Sbjct: 208 LPPSLPPSLERLHLQNNLISKVPRGALSRQ--TQLRELYLQHNQLTDSGLDATTFSKLHS 265
Query: 110 LESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLI 169
LE LDLSHN LT +PA L+ ++L N++R+ V A H ++ L HN +
Sbjct: 266 LEYLDLSHNQLTTVPAG--LPRTLAILHLGRNRIRQ--VEAARLHGARGLRYLLLQHNQL 321
Query: 170 HRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLG 229
P A P + +L+L N L VP LR L L N +A +G
Sbjct: 322 GS-SGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 380
Query: 230 GLTHLSLASLQRL--PELAPSGFRELPGLQVLDLSGNP--------------------KL 267
GLT L+LA RL + FR L L+ LDL+GN +L
Sbjct: 381 GLTELNLA-YNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 439
Query: 268 NWAGAEVFSGLSSLQELDLSGTNL 291
E +GL L+EL L+ L
Sbjct: 440 RMLEPEPLAGLDQLRELSLAHNRL 463
Score = 62.4 bits (150), Expect = 6e-10
Identities = 74/263 (28%), Positives = 115/263 (43%), Gaps = 15/263 (5%)
Query: 42 VDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTS--I 99
VDC GL + P I HL L +N+L+ + + L+ + L L+L +NL++S +
Sbjct: 56 VDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELS--RLSGLRTLNLHNNLISSEGL 113
Query: 100 SPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRA 159
AF L L+ L ++HN L+ P F L +L+ NQ+ E+ F R+
Sbjct: 114 PDEAFESLTQLQHLCVAHNKLSVAP--QFLPRSLRVADLAANQVMEIFPLTFGEKPALRS 171
Query: 160 LHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAV 219
+++ HN P A + I +L+L+ N+L +P L L L N ++
Sbjct: 172 VYL---HNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISK 228
Query: 220 IGPGAFAGLGGLTHLSLASLQRLPE-LAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGL 278
+ GA + L L L Q L + F +L L+ LDLS N V +GL
Sbjct: 229 VPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQL-----TTVPAGL 283
Query: 279 SSLQELDLSGTNLVPLPEALLLH 301
+ G N + EA LH
Sbjct: 284 PRTLAILHLGRNRIRQVEAARLH 306
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/163 (31%), Positives = 68/163 (41%), Gaps = 29/163 (17%)
Query: 46 GLGPHIMPVPIPLDTAHLDLSSNRLEMVN-ESVLAGPGYTTLAGLDLSHNLLTS--ISPT 102
G G +P +P L L N + + ++A PG T L +L++N L S +
Sbjct: 344 GNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTEL---NLAYNRLASARVHHR 400
Query: 103 AFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHV 162
AF RLR L SLDL+ N LT LP T L + L NQLR + Q R L
Sbjct: 401 AFRRLRALRSLDLAGNQLTRLPMGLPTG--LRTLQLQRNQLRMLEPEPLAGLDQLREL-- 456
Query: 163 DLSHNLI-------------------HRLVPHPTRAGLPAPTI 186
L+HN + HRLV H P+P +
Sbjct: 457 SLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCL 499
Score = 28.9 bits (63), Expect = 7.3
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 38 SLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLT 97
+L +D +G +P+ +P L L N+L M+ LA G L L L+HN L
Sbjct: 407 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLA--GLDQLRELSLAHNRLR 464
Query: 98 --SISPTAFSRLRYLE 111
I P + L+ L+
Sbjct: 465 VGDIGPGTWHELQALQ 480
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 78.6 bits (192), Expect = 8e-15
Identities = 83/264 (31%), Positives = 113/264 (42%), Gaps = 32/264 (12%)
Query: 52 MPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTS--ISPTAFSRLRY 109
+P +P L L +N + V L+ T L L L HN LT + T FS+L
Sbjct: 210 LPPSLPPSLERLHLQNNLISKVPRGALSRQ--TQLRELYLQHNQLTDSGLDATTFSKLHS 267
Query: 110 LESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLI 169
LE LDLSHN LT +PA L+ ++L N++R+ V A H ++ L HN +
Sbjct: 268 LEYLDLSHNQLTTVPAG--LPRTLAILHLGRNRIRQ--VEAARLHGARGLRYLLLQHNQL 323
Query: 170 HRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLG 229
P A P + +L+L N L VP LR L L N +A +G
Sbjct: 324 GS-SGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 382
Query: 230 GLTHLSLASLQRL--PELAPSGFRELPGLQVLDLSGNP--------------------KL 267
GLT L+LA RL + FR L L+ LDL+GN +L
Sbjct: 383 GLTELNLA-YNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 441
Query: 268 NWAGAEVFSGLSSLQELDLSGTNL 291
E +GL L+EL L+ L
Sbjct: 442 RMLEPEPLAGLDQLRELSLAHNRL 465
Score = 62.4 bits (150), Expect = 6e-10
Identities = 74/263 (28%), Positives = 115/263 (43%), Gaps = 15/263 (5%)
Query: 42 VDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTS--I 99
VDC GL + P I HL L +N+L+ + + L+ + L L+L +NL++S +
Sbjct: 58 VDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELS--RLSGLRTLNLHNNLISSEGL 115
Query: 100 SPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRA 159
AF L L+ L ++HN L+ P F L +L+ NQ+ E+ F R+
Sbjct: 116 PDEAFESLTQLQHLCVAHNKLSVAP--QFLPRSLRVADLAANQVMEIFPLTFGEKPALRS 173
Query: 160 LHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAV 219
+++ HN P A + I +L+L+ N+L +P L L L N ++
Sbjct: 174 VYL---HNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISK 230
Query: 220 IGPGAFAGLGGLTHLSLASLQRLPE-LAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGL 278
+ GA + L L L Q L + F +L L+ LDLS N V +GL
Sbjct: 231 VPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQL-----TTVPAGL 285
Query: 279 SSLQELDLSGTNLVPLPEALLLH 301
+ G N + EA LH
Sbjct: 286 PRTLAILHLGRNRIRQVEAARLH 308
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/163 (31%), Positives = 68/163 (41%), Gaps = 29/163 (17%)
Query: 46 GLGPHIMPVPIPLDTAHLDLSSNRLEMVN-ESVLAGPGYTTLAGLDLSHNLLTS--ISPT 102
G G +P +P L L N + + ++A PG T L +L++N L S +
Sbjct: 346 GNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTEL---NLAYNRLASARVHHR 402
Query: 103 AFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHV 162
AF RLR L SLDL+ N LT LP T L + L NQLR + Q R L
Sbjct: 403 AFRRLRALRSLDLAGNQLTRLPMGLPTG--LRTLQLQRNQLRMLEPEPLAGLDQLREL-- 458
Query: 163 DLSHNLI-------------------HRLVPHPTRAGLPAPTI 186
L+HN + HRLV H P+P +
Sbjct: 459 SLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCL 501
Score = 28.9 bits (63), Expect = 7.3
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 38 SLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLT 97
+L +D +G +P+ +P L L N+L M+ LA G L L L+HN L
Sbjct: 409 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLA--GLDQLRELSLAHNRLR 466
Query: 98 --SISPTAFSRLRYLE 111
I P + L+ L+
Sbjct: 467 VGDIGPGTWHELQALQ 482
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 78.2 bits (191), Expect = 1e-14
Identities = 93/338 (27%), Positives = 136/338 (40%), Gaps = 54/338 (15%)
Query: 6 LLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVP--------IP 57
LLLL +GA C C C + +DCS +P P +P
Sbjct: 32 LLLLPAAGAGL---CPAPCSCRIPL-----------LDCSR---RKLPAPSWRALSGLLP 74
Query: 58 LDTAHLDLSSNRLEMVNESVLA-------------------GPGYTTLAGLDLSHNLLTS 98
DTA LD S NRL N S+ + G + + L L HN++
Sbjct: 75 PDTAILDFSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPE 134
Query: 99 ISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGR 158
I+ A LESLDLS N ++ + SF L +NLS+N++ + F S
Sbjct: 135 INAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSS- 193
Query: 159 ALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDL---PLRYLSLDGN 215
L V L+ N + + P + P +Q L L NR+ V L LR L + N
Sbjct: 194 LLVVKLNRNRMSMIPPKIFK----LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRN 249
Query: 216 PLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVF 275
++ + GAF GL + L L L + L LQ L +S N + + +
Sbjct: 250 GISKLKDGAFFGLNNMEELELEH-NNLTRVNKGWLYGLRMLQQLYVSQN-AIERISPDAW 307
Query: 276 SGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQD 313
L ELDLS L L E+ + L L+ +++G +
Sbjct: 308 EFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 345
Score = 69.3 bits (168), Expect = 5e-12
Identities = 69/253 (27%), Positives = 109/253 (43%), Gaps = 35/253 (13%)
Query: 65 LSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALP 124
L+ NR+ M+ + P L L+L N + + F L L SL + NG++ L
Sbjct: 199 LNRNRMSMIPPKIFKLPH---LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLK 255
Query: 125 AESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPA 183
+F + + ++ L HN L V+ + L+V S N I R+ P
Sbjct: 256 DGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYV--SQNAIERISPD-------- 305
Query: 184 PTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLP 243
AW L +L L Y N L + AF GL L L+L R+
Sbjct: 306 --------AWEFCQ---RLSELDLSY-----NQLTRLDESAFVGLSLLERLNLGD-NRVT 348
Query: 244 ELAPSGFRELPGLQVLDLSGNPKLNWA---GAEVFSGLSSLQELDLSGTNLVPLPEALLL 300
+A FR L LQ LDL N +++WA +E F+GL+SL +L L G + + + +
Sbjct: 349 HIADGVFRFLSNLQTLDLRNN-EISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFI 407
Query: 301 HLPALQSVSVGQD 313
L +L+ + + +
Sbjct: 408 GLESLEHLDLNNN 420
Score = 34.3 bits (77), Expect = 0.17
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L +S N +E ++ A L+ LDLS+N LT + +AF L LE L+L N +T
Sbjct: 292 LYVSQNAIERISPD--AWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTH 349
Query: 123 LPAESFT-SSPLSDVNLSHNQL 143
+ F S L ++L +N++
Sbjct: 350 IADGVFRFLSNLQTLDLRNNEI 371
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 77.4 bits (189), Expect = 2e-14
Identities = 95/330 (28%), Positives = 150/330 (45%), Gaps = 52/330 (15%)
Query: 16 TTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNE 75
+T C C+C + V C +P IP++T LDLS NRL+ VN
Sbjct: 24 STIGCPARCECSAQN---------KSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNP 74
Query: 76 SVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLS 134
Y L +DLS N++ ++ P AF+ L L SL L N L +P FT S L+
Sbjct: 75 EEFIS--YPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLT 132
Query: 135 DVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWN 194
+++S N++ + F ++L V ++L++ + H +GL +++ L L
Sbjct: 133 KLDISENKIVILLDYMFQDLHNLKSLEVG-DNDLVY--ISHRAFSGL--LSLEQLTLEKC 187
Query: 195 RLHAVP------------------NLRDLP---------LRYLSLDGNPLAVIGP-GAFA 226
L AVP N+ ++P L++L +D PL + P +
Sbjct: 188 NLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLY 247
Query: 227 GLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQEL 284
GL LT LS+ +L +P LA F+ L L L+LS NP ++ A +FS L LQEL
Sbjct: 248 GL-NLTSLSVTNTNLSTVPFLA---FKHLVYLTHLNLSYNP-ISTIEAGMFSDLIRLQEL 302
Query: 285 DLSGTNLVPLPEALLLHLPALQSVSVGQDV 314
+ G L + L L+ ++V Q++
Sbjct: 303 HIVGAQLRTIEPHSFQGLRFLRVLNVSQNL 332
Score = 31.2 bits (69), Expect = 1.5
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 62 HLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLT 121
HL+LS N + + + + L L + L +I P +F LR+L L++S N L
Sbjct: 277 HLNLSYNPISTIEAGMFSD--LIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLE 334
Query: 122 ALPAESFTS-SPLSDVNLSHNQL 143
L F+S L +++++N L
Sbjct: 335 TLEENVFSSPRALEVLSINNNPL 357
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 77.4 bits (189), Expect = 2e-14
Identities = 95/330 (28%), Positives = 138/330 (41%), Gaps = 36/330 (10%)
Query: 3 WPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAH 62
W LLLLA + +PC GC C V+ V CS +P+ IP T +
Sbjct: 9 WTSLLLLA----RPAQPCPMGCDCFVQ-----------EVFCSDEELATVPLDIPPYTKN 53
Query: 63 L---DLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNG 119
+ + S LE + + P T + L+ L P AF L LE L+++ +
Sbjct: 54 IIFVETSFTTLE--TRAFGSNPNLTKVVFLNTQ---LCQFRPDAFGGLPRLEDLEVTGSS 108
Query: 120 LTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTR 178
L F++ + L + L+ N L + F + +LH L N + L P R
Sbjct: 109 FLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLH--LQGNQLQAL---PRR 163
Query: 179 AGLPAPTIQSLNLAWNRLHAVPNLRDLP---LRYLSLDGNPLAVIGPGAFAGLGGLTHLS 235
P +++LNLA N L +P P L+ L L N L+ + G F LG L L
Sbjct: 164 LFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELF 223
Query: 236 LASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLP 295
L S + EL P F +L L+ L L N + +F+ L +L L L L LP
Sbjct: 224 LDS-NNISELPPQVFSQLFCLERLWLQRN-AITHLPLSIFASLGNLTFLSLQWNMLRVLP 281
Query: 296 EALLLHLPALQSVSVGQDVRCRRLVREGTY 325
L H P L +S+ + V EGT+
Sbjct: 282 AGLFAHTPCLVGLSLTHNQ--LETVAEGTF 309
Score = 42.0 bits (97), Expect = 8e-04
Identities = 35/93 (37%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L+ N+LE V E A + L L LS+N +T + F L L L L N LTA
Sbjct: 294 LSLTHNQLETVAEGTFAH--LSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTA 351
Query: 123 L-PAESFTSSPLSDVNLSHNQLREVSVSAFTTH 154
L PA S L ++LS NQL + F T+
Sbjct: 352 LHPALFQNLSKLELLSLSKNQLTTLPEGIFDTN 384
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 86 LAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLR 144
L GL L+HN L +++ F+ L L SL LS+N +T LPA F L + L N L
Sbjct: 291 LVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLT 350
Query: 145 EVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRD 204
+ + F S+ L LS N + L G+ NLA LH P D
Sbjct: 351 ALHPALFQNLSKLELL--SLSKNQLTTL-----PEGIFDTNYNLFNLA---LHGNPWQCD 400
Query: 205 LPLRYL 210
L YL
Sbjct: 401 CHLAYL 406
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 76.6 bits (187), Expect = 3e-14
Identities = 85/326 (26%), Positives = 132/326 (40%), Gaps = 43/326 (13%)
Query: 12 SGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLE 71
SG RPC C+C + +DCS +P P+P A LDLS NRL
Sbjct: 39 SGVAAERPCPTTCRCLGDL-----------LDCSRKRLARLPEPLPSWVARLDLSHNRLS 87
Query: 72 MVNESVLA---------------------GPGYTTLAGLDLSHNLLTSISPTAFSRLRYL 110
+ S ++ GP + L L+ N + I P + L
Sbjct: 88 FIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 147
Query: 111 ESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIH 170
E+LDLS N ++ L +F + L + L+ N++ + F + L + L+ N I
Sbjct: 148 ETLDLSSNNISELQT-AFPALQLKYLYLNSNRVTSMEPGYF-DNLANTLLVLKLNRNRIS 205
Query: 171 RLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDL---PLRYLSLDGNPLAVIGPGAFAG 227
+ P + P +Q L L N++ V L L+ L + N + + GAF G
Sbjct: 206 AIPPKMFK----LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWG 261
Query: 228 LGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLS 287
L + L L L E+ L LQ L LS N +N + + L ELDL+
Sbjct: 262 LSNMEILQL-DHNNLTEITKGWLYGLLMLQELHLSQN-AINRISPDAWEFCQKLSELDLT 319
Query: 288 GTNLVPLPEALLLHLPALQSVSVGQD 313
+L L ++ L L L ++ +G +
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNN 345
Score = 63.2 bits (152), Expect = 3e-10
Identities = 68/252 (26%), Positives = 110/252 (43%), Gaps = 15/252 (5%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L+ NR+ + + P L L+L+ N + ++ F L L+SL + NG+T
Sbjct: 197 LKLNRNRISAIPPKMFKLP---QLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTK 253
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L +F S + + L HN L E++ + LH LS N I+R+ P
Sbjct: 254 LMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELH--LSQNAINRISPDAWEF-- 309
Query: 182 PAPTIQSLNLAWNRLHAVPNLRDLPLRYLS---LDGNPLAVIGPGAFAGLGGLTHLSLAS 238
+ L+L +N L + + L L L+ + N ++ I AF GL L L L +
Sbjct: 310 -CQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 368
Query: 239 --LQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPE 296
+ E F L L+ L L GN ++ + F+GL +L+ LDLS ++ L
Sbjct: 369 NEISWTIEDMNGAFSGLDKLRRLILQGN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQG 427
Query: 297 ALLLHLPALQSV 308
+ LQ +
Sbjct: 428 NAFSQMKKLQQL 439
Score = 57.8 bits (138), Expect = 1e-08
Identities = 61/201 (30%), Positives = 91/201 (45%), Gaps = 27/201 (13%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTA 122
L L N L + + L G L L LS N + ISP A+ + L LDL+ N L+
Sbjct: 268 LQLDHNNLTEITKGWLYG--LLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR 325
Query: 123 LPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGL 181
L SF S L+ +++ +N++ ++ AF S + L DL +N I
Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTL--DLKNNEI------------ 371
Query: 182 PAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQR 241
+ TI+ +N A++ L LR L L GN + I AF GL L HL L+
Sbjct: 372 -SWTIEDMNGAFSGLD--------KLRRLILQGNRIRSITKKAFTGLDALEHLDLSD-NA 421
Query: 242 LPELAPSGFRELPGLQVLDLS 262
+ L + F ++ LQ L L+
Sbjct: 422 IMSLQGNAFSQMKKLQQLHLN 442
Score = 33.1 bits (74), Expect = 0.39
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 63 LDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL 120
L L NR+ + + G L LDLS N + S+ AFS+++ L+ L L+ + L
Sbjct: 391 LILQGNRIRSITKKAFTG--LDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,988,957
Number of Sequences: 37866
Number of extensions: 750660
Number of successful extensions: 3622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 1852
Number of HSP's gapped (non-prelim): 887
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.