Guide to the Human Genome
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Search of human proteins with 45935385

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
         (1247 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]           2526   0.0  
gi|48762709 SAM domain, SH3 domain and nuclear localization sign...   263   1e-69
gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]             244   5e-64
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   1e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          55   5e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          55   5e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          55   5e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   1e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    52   3e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    51   6e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    51   6e-06
gi|30089948 protein phosphatase 1E [Homo sapiens]                      51   6e-06
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           50   1e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    50   1e-05
gi|157168329 formin 1 [Homo sapiens]                                   50   1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   1e-05
gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]     49   2e-05
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                49   3e-05
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                49   3e-05
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                49   3e-05
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             49   4e-05
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    48   5e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              48   7e-05
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    47   9e-05
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    47   9e-05
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    47   9e-05
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    47   1e-04
gi|239756307 PREDICTED: similar to ubiquitin-associated protein ...    47   1e-04
gi|239750857 PREDICTED: similar to ubiquitin-associated protein ...    47   1e-04
gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]            47   1e-04

>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
          Length = 1247

 Score = 2526 bits (6546), Expect = 0.0
 Identities = 1247/1247 (100%), Positives = 1247/1247 (100%)

Query: 1    MEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNID 60
            MEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNID
Sbjct: 1    MEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNID 60

Query: 61   DLAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSA 120
            DLAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSA
Sbjct: 61   DLAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSA 120

Query: 121  VSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVAS 180
            VSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVAS
Sbjct: 121  VSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVAS 180

Query: 181  EITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSS 240
            EITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSS
Sbjct: 181  EITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSS 240

Query: 241  NCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVL 300
            NCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVL
Sbjct: 241  NCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVL 300

Query: 301  DERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFSKGESR 360
            DERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFSKGESR
Sbjct: 301  DERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFSKGESR 360

Query: 361  GLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHV 420
            GLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHV
Sbjct: 361  GLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHV 420

Query: 421  GSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGL 480
            GSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGL
Sbjct: 421  GSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGL 480

Query: 481  DGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVK 540
            DGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVK
Sbjct: 481  DGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVK 540

Query: 541  SEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNN 600
            SEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNN
Sbjct: 541  SEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNN 600

Query: 601  KVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYE 660
            KVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYE
Sbjct: 601  KVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYE 660

Query: 661  DLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDSQGLSGC 720
            DLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDSQGLSGC
Sbjct: 661  DLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDSQGLSGC 720

Query: 721  SPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQ 780
            SPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQ
Sbjct: 721  SPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQ 780

Query: 781  GQEEGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSL 840
            GQEEGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSL
Sbjct: 781  GQEEGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSL 840

Query: 841  DDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRF 900
            DDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRF
Sbjct: 841  DDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRF 900

Query: 901  SEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGT 960
            SEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGT
Sbjct: 901  SEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGT 960

Query: 961  HHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLP 1020
            HHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLP
Sbjct: 961  HHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLP 1020

Query: 1021 VKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPA 1080
            VKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPA
Sbjct: 1021 VKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPA 1080

Query: 1081 LTRKVSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERD 1140
            LTRKVSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERD
Sbjct: 1081 LTRKVSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERD 1140

Query: 1141 VAANMDQIRVKQLRKQHRMAIPSGGLTEICRKPVSPGCISSVSDWLISIGLPMYAGTLST 1200
            VAANMDQIRVKQLRKQHRMAIPSGGLTEICRKPVSPGCISSVSDWLISIGLPMYAGTLST
Sbjct: 1141 VAANMDQIRVKQLRKQHRMAIPSGGLTEICRKPVSPGCISSVSDWLISIGLPMYAGTLST 1200

Query: 1201 AGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLPPGPEAM 1247
            AGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLPPGPEAM
Sbjct: 1201 AGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLPPGPEAM 1247


>gi|48762709 SAM domain, SH3 domain and nuclear localization
           signals, 1 [Homo sapiens]
          Length = 373

 Score =  263 bits (671), Expect = 1e-69
 Identities = 156/346 (45%), Positives = 216/346 (62%), Gaps = 25/346 (7%)

Query: 404 RTCSFGGFD-LTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPTASRIS-LGKKVKSVKETM 461
           R+ SFG FD   N SL    ++++    EGD       +S T++    LGKK++++  TM
Sbjct: 20  RSSSFGNFDRFRNNSLSKPDDSTE--AHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTM 77

Query: 462 RKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDP---EHLDKPKLKAGGSVESLRSSLSGQ 518
           +K++ KKY  ++SE+    DG   + P    DP    H +K  LKA  S++SL    SGQ
Sbjct: 78  KKKVGKKYIKALSEEKDEEDG-ENAHPYRNSDPVIGTHTEKVSLKASDSMDSL---YSGQ 133

Query: 519 SSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLK 578
           SS SG  +++    TSNR+S + +D    + PY GPFCGRARVHTDFTPSPYDTDSLK+K
Sbjct: 134 SSSSG--ITSCSDGTSNRDSFRLDD----DGPYSGPFCGRARVHTDFTPSPYDTDSLKIK 187

Query: 579 KGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSV 638
           KGDIIDII K PMG W G+LNNKVG FKFIYVDV+SE+E  PK+  +  R+    + K++
Sbjct: 188 KGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKK-IKANRRSNSKKSKTL 246

Query: 639 EDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAV------E 692
           ++ L+RI+L+E+  T L NGYE L+  K ++E  L ELNI +P+ R  LL+A       E
Sbjct: 247 QEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEE 306

Query: 693 LLQEYDSNSDQSGSQEKLLVDSQGLSGCSPRDSGCYESSENLENGK 738
           ++QE ++  +       + ++   L  C PRDSGCY SS N +NGK
Sbjct: 307 IIQEQENEPEPLSLSSDISLNKSQLDDC-PRDSGCYISSGNSDNGK 351



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 1181 SVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLF 1238
            ++ ++L  I L  Y  TL   G+ TL  +  +  + L E  I      R+LLSAA  F
Sbjct: 245  TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENF 302


>gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
          Length = 380

 Score =  244 bits (622), Expect = 5e-64
 Identities = 144/295 (48%), Positives = 185/295 (62%), Gaps = 20/295 (6%)

Query: 450 LGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDGMP-GSPPPSQPDPEHLDKPKLKAGGS 507
           LGKK ++V   TM ++M K    ++SE+ +  D +  GS  P+ PD   LD P       
Sbjct: 72  LGKKWRAVISRTMNRKMGKMMVKALSEEMA--DTLEEGSASPTSPDYS-LDSP------G 122

Query: 508 VESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKSEDGD-DEEPP---YRGPFCGRARVHT 563
            E +  + S Q       +S   S+ S   S     G   EEPP   Y GPFCGRARVHT
Sbjct: 123 PEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHT 182

Query: 564 DFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRP 623
           DFTPSPYD DSLKL+KGD+I II KPP+GTW+GLLN KVG+FKFIYVDVL E+     RP
Sbjct: 183 DFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARP 242

Query: 624 TRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEH 683
           +RR+ KG+ P+PK++ +LL+RI L+EH  T L NGY+ L+ FK L E  L+ELNI DP+H
Sbjct: 243 SRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQH 302

Query: 684 RAVLLTAVELLQEYDSNSDQS-----GSQEKLLVDSQGLSGCSPRDSGCYESSEN 733
           RA LLTA ELL +YD+ S+++      SQE +           PRDSGC+E SE+
Sbjct: 303 RAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSES 357


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 89/347 (25%), Positives = 122/347 (35%), Gaps = 36/347 (10%)

Query: 737  GKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLGGGLAPDTS 796
            G  +  S  S  S+TEPS  +  R   G     P  +S            L     P +S
Sbjct: 204  GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS------------LSSSATPLSS 251

Query: 797  KSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHS---LDDLQVEPGAEQDV 853
             +   P   G  +          +  + L  PQ   T PR  +   L  L   P A    
Sbjct: 252  PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSP 309

Query: 854  PTEVTEPPPQIVPEVPQKTTASSTKAQPLE---QDSAVDNALLLTQSKRFSEPQKLTTKK 910
               +    P  +P  P  ++ +   A PL       +   +L    S   + P + TT  
Sbjct: 310  SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369

Query: 911  LEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTK--E 968
               ++ A+   L  P   P      PP A   LA  PL+             PL T   +
Sbjct: 370  GSPTLQATHSFLPSPPLSP--LATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQ 426

Query: 969  GVDAEQRMQPKIPSQPPPVPAKKS--RERLANGLHPVPMGPSGALPSPDAPCLPVKRGSP 1026
              +A      + P  PPP P  ++      +  + P    PS A PS  AP L V    P
Sbjct: 427  APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486

Query: 1027 ASPT-SPSDCPPALAPRPLSGQA-------PGSPPSTRPPPWLSELP 1065
            ASP  SPS  PP  AP PL+          P +PP+   PP L  LP
Sbjct: 487  ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP-LQALP 532



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 77/303 (25%), Positives = 110/303 (36%), Gaps = 46/303 (15%)

Query: 782  QEEGRLGGGLAPDTSKSCDPPGVTGLN-KNRRSLPVSICRSCETLEGPQTVDTWPRSHSL 840
            +  G +GG   P+++    P    G + +N  S P +  R       P   +T P   S 
Sbjct: 60   ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG---ERAPPAKNTSPGPVS- 115

Query: 841  DDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRF 900
                  PG         T P P  + +   + +A  T A+    ++   +AL     +  
Sbjct: 116  -----SPGRASGT----TRPGP--LGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 901  SEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGT 960
            S P   T      ++A   R       LPR   +  P       R P EG RK       
Sbjct: 165  SGPTPGTPSP---AMARRSRAAGTEVGLPRPAPSARP-------RPPTEGPRKSVSSASE 214

Query: 961  HHPLGTKEGVDAEQRMQPKIPSQPPPV--PAKKSRERLANGLH-PVPMGPS--GALPSPD 1015
            H    T E   A +R     PS    +  PA +S    A  L  P   GPS  G   +P 
Sbjct: 215  H---STTEPSPAARRR----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267

Query: 1016 APCLPVKRG----SPASPTSP-SDCPPALAP---RPLSGQAPGSPPSTRPPPWLSELPEN 1067
             P  P  +G     P   T P  D  PAL P    PL+  +P +   ++ PP L   P +
Sbjct: 268  HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS 327

Query: 1068 TSL 1070
            +SL
Sbjct: 328  SSL 330



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 24/149 (16%)

Query: 923  SPPQCLPRNYDAQPPG-AKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIP 981
            SPP   P +  A PP  A   LA  PL+             P        A    Q   P
Sbjct: 453  SPPASPPVSPSATPPSQAPPSLAAPPLQ--------VPPSPPASPPMSPSATPPPQAPPP 504

Query: 982  SQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPAS--PTSPSDCPPAL 1039
               PP+   K   +    L   P+    ALPSP A        SP++  P SP   PP  
Sbjct: 505  LAAPPLQLAKPPPQAPPALATPPLQ---ALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561

Query: 1040 APRPLSG---QAPGSPPST-------RPP 1058
            AP  L+    Q P SPP++       RPP
Sbjct: 562  APPVLAAPLLQVPPSPPASPTLQAPRRPP 590



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 9/89 (10%)

Query: 980  IPSQPPPVPAKKSRERLAN-GLHPVPMGPSGALPSPDAPCLPVKRGSPASPT-------- 1030
            +PS P   P +      A+  + P+   P  A P   AP L V    PASPT        
Sbjct: 531  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590

Query: 1031 SPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
            +P        PR     APG PP     P
Sbjct: 591  TPGPDTSVSGPRLTLALAPGPPPPPSRSP 619


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 89/390 (22%), Positives = 134/390 (34%), Gaps = 79/390 (20%)

Query: 729  ESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLG 788
            E+S  L++ K ++  + S     + +    ++ Q  + P  P           + EG   
Sbjct: 85   EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP----------SEGEGESS 134

Query: 789  GGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDD-LQVEP 847
               + +   S DP  +     NR + P        ++  PQ  ++   S +    LQ +P
Sbjct: 135  DSRSVNDEGSSDPKDID--QDNRSTSP--------SIPSPQDNESDSDSSAQQQMLQAQP 184

Query: 848  GAEQDVPTEVTEPPPQIVPEVPQ-----------------KTTASSTKAQPLEQDSAVDN 890
             A Q  PT VT  P    P  PQ                   TAS    QP    + V +
Sbjct: 185  PALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 243

Query: 891  ALLLTQSKRFSEPQKLTTKK----------LEGSIAASGRGLSPPQCLPRNYDAQPPGAK 940
              +  Q      PQ+  +            L+    ++G+  +P    P  +   PPG  
Sbjct: 244  THI--QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 300

Query: 941  HGLARTPLEGHRKGHEFEGT-------HHPLGTKEGV-------------DAEQRMQPKI 980
            H L   PL  H    +  G          PLGT                  A Q  QP  
Sbjct: 301  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360

Query: 981  PSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALA 1040
                PP P           + P P  P   LP+P A   P     P+  +  ++ PP  A
Sbjct: 361  EQPLPPAPLAMPH------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 414

Query: 1041 PRPLSGQAPGSPPSTRPPPWLSELPENTSL 1070
             +PLS  +   PPS  PPP L  +P++  L
Sbjct: 415  LKPLSSLSTHHPPSAHPPP-LQLMPQSQPL 443


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 89/390 (22%), Positives = 134/390 (34%), Gaps = 79/390 (20%)

Query: 729  ESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLG 788
            E+S  L++ K ++  + S     + +    ++ Q  + P  P           + EG   
Sbjct: 639  EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP----------SEGEGESS 688

Query: 789  GGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDD-LQVEP 847
               + +   S DP  +     NR + P        ++  PQ  ++   S +    LQ +P
Sbjct: 689  DSRSVNDEGSSDPKDID--QDNRSTSP--------SIPSPQDNESDSDSSAQQQMLQAQP 738

Query: 848  GAEQDVPTEVTEPPPQIVPEVPQ-----------------KTTASSTKAQPLEQDSAVDN 890
             A Q  PT VT  P    P  PQ                   TAS    QP    + V +
Sbjct: 739  PALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 797

Query: 891  ALLLTQSKRFSEPQKLTTKK----------LEGSIAASGRGLSPPQCLPRNYDAQPPGAK 940
              +  Q      PQ+  +            L+    ++G+  +P    P  +   PPG  
Sbjct: 798  THI--QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 854

Query: 941  HGLARTPLEGHRKGHEFEGT-------HHPLGTKEGV-------------DAEQRMQPKI 980
            H L   PL  H    +  G          PLGT                  A Q  QP  
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914

Query: 981  PSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALA 1040
                PP P           + P P  P   LP+P A   P     P+  +  ++ PP  A
Sbjct: 915  EQPLPPAPLAMPH------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968

Query: 1041 PRPLSGQAPGSPPSTRPPPWLSELPENTSL 1070
             +PLS  +   PPS  PPP L  +P++  L
Sbjct: 969  LKPLSSLSTHHPPSAHPPP-LQLMPQSQPL 997



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 17/244 (6%)

Query: 252 TEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVH 311
           T+  + FK+  +L    + V       + +K+       +H           S L SG  
Sbjct: 530 TDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRK 589

Query: 312 KKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFS---KGESRGLIKPPKK 368
           K+P   DG      ED   S   SPS++S  +  +  + VK  +   K E+   +K  K+
Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649

Query: 369 MGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPM 428
                +  + E+A + S   T+ +      S S G      G    +RS++    +SDP 
Sbjct: 650 QREKVA-SDTEEADRTSSKKTKTQEISRPNSPSEGE-----GESSDSRSVN-DEGSSDPK 702

Query: 429 GKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGLDGMPGSPP 488
             + D          T+  I   +  +S  ++  ++   +      +  +G+   P S P
Sbjct: 703 DIDQD-------NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 489 PSQP 492
           P  P
Sbjct: 756 PGTP 759


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 89/390 (22%), Positives = 134/390 (34%), Gaps = 79/390 (20%)

Query: 729  ESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLG 788
            E+S  L++ K ++  + S     + +    ++ Q  + P  P           + EG   
Sbjct: 639  EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP----------SEGEGESS 688

Query: 789  GGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDD-LQVEP 847
               + +   S DP  +     NR + P        ++  PQ  ++   S +    LQ +P
Sbjct: 689  DSRSVNDEGSSDPKDID--QDNRSTSP--------SIPSPQDNESDSDSSAQQQMLQAQP 738

Query: 848  GAEQDVPTEVTEPPPQIVPEVPQ-----------------KTTASSTKAQPLEQDSAVDN 890
             A Q  PT VT  P    P  PQ                   TAS    QP    + V +
Sbjct: 739  PALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 797

Query: 891  ALLLTQSKRFSEPQKLTTKK----------LEGSIAASGRGLSPPQCLPRNYDAQPPGAK 940
              +  Q      PQ+  +            L+    ++G+  +P    P  +   PPG  
Sbjct: 798  THI--QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 854

Query: 941  HGLARTPLEGHRKGHEFEGT-------HHPLGTKEGV-------------DAEQRMQPKI 980
            H L   PL  H    +  G          PLGT                  A Q  QP  
Sbjct: 855  HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914

Query: 981  PSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALA 1040
                PP P           + P P  P   LP+P A   P     P+  +  ++ PP  A
Sbjct: 915  EQPLPPAPLAMPH------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968

Query: 1041 PRPLSGQAPGSPPSTRPPPWLSELPENTSL 1070
             +PLS  +   PPS  PPP L  +P++  L
Sbjct: 969  LKPLSSLSTHHPPSAHPPP-LQLMPQSQPL 997



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 17/244 (6%)

Query: 252 TEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVH 311
           T+  + FK+  +L    + V       + +K+       +H           S L SG  
Sbjct: 530 TDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRK 589

Query: 312 KKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFS---KGESRGLIKPPKK 368
           K+P   DG      ED   S   SPS++S  +  +  + VK  +   K E+   +K  K+
Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649

Query: 369 MGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPM 428
                +  + E+A + S   T+ +      S S G      G    +RS++    +SDP 
Sbjct: 650 QREKVA-SDTEEADRTSSKKTKTQEISRPNSPSEGE-----GESSDSRSVN-DEGSSDPK 702

Query: 429 GKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGLDGMPGSPP 488
             + D          T+  I   +  +S  ++  ++   +      +  +G+   P S P
Sbjct: 703 DIDQD-------NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 489 PSQP 492
           P  P
Sbjct: 756 PGTP 759


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 79/291 (27%), Positives = 108/291 (37%), Gaps = 32/291 (10%)

Query: 788  GGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDLQVEP 847
            GGGL    S+S      T L+   RS             GP    T PR+ +        
Sbjct: 222  GGGLQRPASRSLSS-SATPLSSPARS-------------GPSARGT-PRAPAHPSQPKPK 266

Query: 848  GAEQDVPTEVTEPPPQIVPEV-PQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKL 906
            G +   P +VT P     P + P  ++  +T +       +   +L    S   + P + 
Sbjct: 267  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326

Query: 907  TTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGT 966
            TT     ++ A+   L  P   P      PP A   LA  PL+             PL T
Sbjct: 327  TTSLGSPTLQATHSFLPSPPLSP--LATPPPQAPPALALPPLQAP-PSPPASPPLSPLAT 383

Query: 967  K--EGVDAEQRMQPKIPSQPPPVPAKKS--RERLANGLHPVPMGPSGALPSPDAPCLPVK 1022
               +  +A      + P  PPP P  ++      +  + P    PS A PS  AP L V 
Sbjct: 384  PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 1023 RGSPASPT-SPSDCPPALAPRPLSGQA-------PGSPPSTRPPPWLSELP 1065
               PASP  SPS  PP  AP PL+          P +PP+   PP L  LP
Sbjct: 444  PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP-LQALP 493



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 48/143 (33%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 936  PPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPV--PAKKSR 993
            P  A     R P EG RK       H    T E   A +R     PS    +  PA +S 
Sbjct: 181  PRPAPSARPRPPTEGPRKSVSSASEH---STTEPSPAARRR----PSAGGGLQRPASRSL 233

Query: 994  ERLANGLH-PVPMGPS--GALPSPDAPCLPVKRG----SPASPTSP-SDCPPALAP---R 1042
               A  L  P   GPS  G   +P  P  P  +G     P   T P  D  PAL P    
Sbjct: 234  SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293

Query: 1043 PLSGQAPGSPPSTRPPPWLSELP 1065
            PL+  +P +PPS   PP L  LP
Sbjct: 294  PLATPSPSAPPSPSAPPSLQTLP 316



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 33/223 (14%)

Query: 848  GAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKLT 907
            G E  +P       P+   E P+K+ +S+++    E   A         ++R        
Sbjct: 175  GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA---------ARRRPSAGGGL 225

Query: 908  TKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHR-KGHEFEGTHHPLGT 966
             +    S+++S   LS P        A+   +  G  R P    + K    +    P  T
Sbjct: 226  QRPASRSLSSSATPLSSP--------ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277

Query: 967  KEGVDAEQRMQP--------KIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPC 1018
                DA   + P          PS PP   A  S + L +   P    PS A  S  +P 
Sbjct: 278  PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS---PPATPPSQATTSLGSPT 334

Query: 1019 LPVKRGS-PASPTSPSDCPPALAPRPLS---GQAPGSPPSTRP 1057
            L       P+ P SP   PP  AP  L+    QAP SPP++ P
Sbjct: 335  LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 377



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 24/149 (16%)

Query: 923  SPPQCLPRNYDAQPPG-AKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIP 981
            SPP   P +  A PP  A   LA  PL+             P        A    Q   P
Sbjct: 414  SPPASPPVSPSATPPSQAPPSLAAPPLQ--------VPPSPPASPPMSPSATPPPQAPPP 465

Query: 982  SQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPAS--PTSPSDCPPAL 1039
               PP+   K   +    L   P+    ALPSP A        SP++  P SP   PP  
Sbjct: 466  LAAPPLQLAKPPPQAPPALATPPLQ---ALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522

Query: 1040 APRPLSG---QAPGSPPST-------RPP 1058
            AP  L+    Q P SPP++       RPP
Sbjct: 523  APPVLAAPLLQVPPSPPASPTLQAPRRPP 551



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 9/89 (10%)

Query: 980  IPSQPPPVPAKKSRERLAN-GLHPVPMGPSGALPSPDAPCLPVKRGSPASPT-------- 1030
            +PS P   P +      A+  + P+   P  A P   AP L V    PASPT        
Sbjct: 492  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551

Query: 1031 SPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
            +P        PR     APG PP     P
Sbjct: 552  TPGPDTSVSGPRLTLALAPGPPPPPSRSP 580


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 63/231 (27%), Positives = 86/231 (37%), Gaps = 36/231 (15%)

Query: 846  EPGAEQ--DVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQD-SAVDNALLLTQSKRFSE 902
            +P A+Q    PT     PPQ     P    ASS +   L Q  SA   A+L   S +   
Sbjct: 641  QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL 700

Query: 903  PQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPL-EGHRKGHEFEGTH 961
            PQ+ + + L    +A G  LS P  +     + PP A+     TP+ +G   G +   + 
Sbjct: 701  PQERSQQPL----SAEGPHLSVPASV---IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQ 753

Query: 962  HPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPD------ 1015
                    + A   ++   PS  P +P            H  P+G S  LPSP       
Sbjct: 754  ASPAPAPQIPAAAPLKGPGPSSSPSLP------------HQAPLGDSPHLPSPHPTRPPS 801

Query: 1016 -APCLPVKRGSPASPTSPSDCPPALAPRPLSG------QAPGSPPSTRPPP 1059
              P  P     P S      CPP  AP  L G      Q    PP++ P P
Sbjct: 802  RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP 852



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 32/104 (30%)

Query: 977  QPKIPSQPPP---------VPAKKSRERLANGLHPVPMG------------------PSG 1009
            +P  P  PPP          PA    + L    H VP G                    G
Sbjct: 931  EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG 990

Query: 1010 ALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPP 1053
             L SP A  L   +    +PT+PS  P   AP P++  A G PP
Sbjct: 991  PLTSPAASVLVSGQAPSGTPTAPSHAP---APAPMA--ATGLPP 1029


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 49/161 (30%), Positives = 60/161 (37%), Gaps = 23/161 (14%)

Query: 921  GLSPPQCLP---RNYDAQPPGAKHGLARTPLE--GHRKGH-EFEGTHHPLGTKEGVDAEQ 974
            G S P  LP   R+  A+P     G  R P+   GHR G  E +    P    +      
Sbjct: 122  GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 975  RMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRG---------- 1024
             + P +PS P P+ +         G  PVP GP    P P  P  P  RG          
Sbjct: 182  SIPPPVPSTPRPIQSSPHNR----GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQ 237

Query: 1025 SPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
            SP S +SP    P L P P        PP   PPP +   P
Sbjct: 238  SPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPVGNRP 275



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 46/155 (29%), Positives = 56/155 (36%), Gaps = 21/155 (13%)

Query: 911  LEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGV 970
            L  S   S R   PP    R  D +PP         P  G+R     E    P       
Sbjct: 240  LSSSSPFSNRPPLPPTP-SRALDDKPPPPP------PPVGNRPSIHREAVPPPPPQNNKP 292

Query: 971  DAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPT 1030
                  +P   SQ PP P   SR     G  P+P   SG   + + P LP +  S +S T
Sbjct: 293  PVPSTPRPSASSQAPPPPPPPSRP----GPPPLPPSSSG---NDETPRLPQRNLSLSSST 345

Query: 1031 SPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
             P   P    P P        PPS RPPP + + P
Sbjct: 346  PPLPSPGRSGPLP-------PPPSERPPPPVRDPP 373



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 978  PKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPS--PDAPCLPVKRGSPASPTSPSDC 1035
            P  PS+ PP P +    R      P P+  +G+     P  P LP + G  +  + P   
Sbjct: 358  PPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-- 415

Query: 1036 PPALAPRPLSGQAPGSPPST 1055
            PP    RP +G  P  PPST
Sbjct: 416  PPLPPDRPSAGAPPPPPPST 435



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 14/124 (11%)

Query: 459 ETMRKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPKLKAGGSVESL------- 511
           E  R RM        S+ DS    +P +P P Q  P +   P +  G    S        
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPF 222

Query: 512 ---RSSLSGQSSMSGQTVSTTDSSTSNRESVK---SEDGDDEEPPYRGPFCGRARVHTDF 565
              R +  G  S+    +S++ S  SNR  +    S   DD+ PP   P   R  +H + 
Sbjct: 223 PGNRGTALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 566 TPSP 569
            P P
Sbjct: 282 VPPP 285



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 69/294 (23%), Positives = 96/294 (32%), Gaps = 29/294 (9%)

Query: 788  GGGLAPDTSKSCDP-PGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDLQVE 846
            GG   P    +  P PG  G      S+  S   S         +   P S +LDD    
Sbjct: 208  GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTP-SRALDDKPPP 266

Query: 847  P----GAEQDVPTEVTEPPPQI-----VPEVPQKTTASSTKAQPLEQDSAVDNALLLTQS 897
            P    G    +  E   PPP       VP  P + +ASS    P    S      L   S
Sbjct: 267  PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 898  KRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEF 957
                E  +L  + L  S+++S    +PP   P      PP       R P        + 
Sbjct: 326  SGNDETPRLPQRNL--SLSSS----TPPLPSPGRSGPLPPPPSE---RPP----PPVRDP 372

Query: 958  EGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPV--PMGPSGALPSPD 1015
             G   PL     V         +P+ P  +P++   +   +G  P   P  PS   P P 
Sbjct: 373  PGRSGPLPPPPPVSRNGSTSRALPATPQ-LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTS 1069
             P   ++ G   SP    +        P+S   P  P       + S+L  N S
Sbjct: 432  PPSTSIRNGFQDSPCE-DEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNES 484


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 49/161 (30%), Positives = 60/161 (37%), Gaps = 23/161 (14%)

Query: 921  GLSPPQCLP---RNYDAQPPGAKHGLARTPLE--GHRKGH-EFEGTHHPLGTKEGVDAEQ 974
            G S P  LP   R+  A+P     G  R P+   GHR G  E +    P    +      
Sbjct: 122  GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 975  RMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRG---------- 1024
             + P +PS P P+ +         G  PVP GP    P P  P  P  RG          
Sbjct: 182  SIPPPVPSTPRPIQSSPHNR----GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQ 237

Query: 1025 SPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
            SP S +SP    P L P P        PP   PPP +   P
Sbjct: 238  SPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPVGNRP 275



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 46/155 (29%), Positives = 56/155 (36%), Gaps = 21/155 (13%)

Query: 911  LEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGV 970
            L  S   S R   PP    R  D +PP         P  G+R     E    P       
Sbjct: 240  LSSSSPFSNRPPLPPTP-SRALDDKPPPPP------PPVGNRPSIHREAVPPPPPQNNKP 292

Query: 971  DAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPT 1030
                  +P   SQ PP P   SR     G  P+P   SG   + + P LP +  S +S T
Sbjct: 293  PVPSTPRPSASSQAPPPPPPPSRP----GPPPLPPSSSG---NDETPRLPQRNLSLSSST 345

Query: 1031 SPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
             P   P    P P        PPS RPPP + + P
Sbjct: 346  PPLPSPGRSGPLP-------PPPSERPPPPVRDPP 373



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 978  PKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPS--PDAPCLPVKRGSPASPTSPSDC 1035
            P  PS+ PP P +    R      P P+  +G+     P  P LP + G  +  + P   
Sbjct: 358  PPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-- 415

Query: 1036 PPALAPRPLSGQAPGSPPST 1055
            PP    RP +G  P  PPST
Sbjct: 416  PPLPPDRPSAGAPPPPPPST 435



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 14/124 (11%)

Query: 459 ETMRKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPKLKAGGSVESL------- 511
           E  R RM        S+ DS    +P +P P Q  P +   P +  G    S        
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPF 222

Query: 512 ---RSSLSGQSSMSGQTVSTTDSSTSNRESVK---SEDGDDEEPPYRGPFCGRARVHTDF 565
              R +  G  S+    +S++ S  SNR  +    S   DD+ PP   P   R  +H + 
Sbjct: 223 PGNRGTALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 566 TPSP 569
            P P
Sbjct: 282 VPPP 285



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 69/294 (23%), Positives = 96/294 (32%), Gaps = 29/294 (9%)

Query: 788  GGGLAPDTSKSCDP-PGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDLQVE 846
            GG   P    +  P PG  G      S+  S   S         +   P S +LDD    
Sbjct: 208  GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTP-SRALDDKPPP 266

Query: 847  P----GAEQDVPTEVTEPPPQI-----VPEVPQKTTASSTKAQPLEQDSAVDNALLLTQS 897
            P    G    +  E   PPP       VP  P + +ASS    P    S      L   S
Sbjct: 267  PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 898  KRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEF 957
                E  +L  + L  S+++S    +PP   P      PP       R P        + 
Sbjct: 326  SGNDETPRLPQRNL--SLSSS----TPPLPSPGRSGPLPPPPSE---RPP----PPVRDP 372

Query: 958  EGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPV--PMGPSGALPSPD 1015
             G   PL     V         +P+ P  +P++   +   +G  P   P  PS   P P 
Sbjct: 373  PGRSGPLPPPPPVSRNGSTSRALPATPQ-LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTS 1069
             P   ++ G   SP    +        P+S   P  P       + S+L  N S
Sbjct: 432  PPSTSIRNGFQDSPCE-DEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNES 484


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 22/31 (70%), Positives = 24/31 (77%)

Query: 10 GPEPEPEPEPEPEPAPEPEPEPKPGAGTSEA 40
          G EPEPEPEPEPEP PE EPEP+P    +EA
Sbjct: 28 GGEPEPEPEPEPEPEPESEPEPEPELVEAEA 58



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 23/32 (71%), Positives = 24/32 (75%), Gaps = 1/32 (3%)

Query: 2  EDAGAAGPG-PEPEPEPEPEPEPAPEPEPEPK 32
          E  G  G G PEPEPEPEPEPEP  EPEPEP+
Sbjct: 21 EFRGPCGGGEPEPEPEPEPEPEPESEPEPEPE 52



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 21/33 (63%), Positives = 22/33 (66%)

Query: 8  GPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEA 40
          GP    EPEPEPEPEP PEPE EP+P     EA
Sbjct: 24 GPCGGGEPEPEPEPEPEPEPESEPEPEPELVEA 56


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 20/32 (62%), Positives = 23/32 (71%)

Query: 2   EDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKP 33
           E  G+  P  EPEPEPEPEP P P PEP+P+P
Sbjct: 98  EPVGSPEPESEPEPEPEPEPVPVPPPEPQPEP 129



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 18/23 (78%), Positives = 20/23 (86%)

Query: 11  PEPEPEPEPEPEPAPEPEPEPKP 33
           PEPEPEPEP P P PEP+PEP+P
Sbjct: 109 PEPEPEPEPVPVPPPEPQPEPQP 131



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 17/25 (68%), Positives = 19/25 (76%)

Query: 9   PGPEPEPEPEPEPEPAPEPEPEPKP 33
           P PEPEPEP P P P P+PEP+P P
Sbjct: 109 PEPEPEPEPVPVPPPEPQPEPQPLP 133



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 13/46 (28%)

Query: 9   PGPEPEPEPEPEPEPAPEP----------EPEPKPGA---GTSEAF 41
           P PEP+PEP+P P+PAP P          EPEP P     GT+  F
Sbjct: 121 PPPEPQPEPQPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGF 166



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 14/24 (58%), Positives = 18/24 (75%)

Query: 9   PGPEPEPEPEPEPEPAPEPEPEPK 32
           P P P PEP+PEP+P P+P P P+
Sbjct: 117 PVPVPPPEPQPEPQPLPDPAPLPE 140



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 14/22 (63%), Positives = 16/22 (72%)

Query: 12  EPEPEPEPEPEPAPEPEPEPKP 33
           + EP   PEPE  PEPEPEP+P
Sbjct: 96  QQEPVGSPEPESEPEPEPEPEP 117



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 39/147 (26%), Positives = 52/147 (35%), Gaps = 31/147 (21%)

Query: 802 PGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHS---------------------L 840
           PG  G      S P S   S      PQ+  + P SHS                      
Sbjct: 33  PGGGGSGSGSSSPPSSSSCSSRNKYQPQSGSSGPSSHSPPAAMALQSQASEEAKGPWQEA 92

Query: 841 DDLQVEPGAEQDVPTEVTEPPPQIVPE-VPQKTTASSTKAQPLEQDSAVDNALLLTQSKR 899
           D  Q EP      P   +EP P+  PE VP        + QPL   + +    L  +S+R
Sbjct: 93  DQEQQEPVGS---PEPESEPEPEPEPEPVPVPPPEPQPEPQPLPDPAPLPE--LEFESER 147

Query: 900 FSEPQKLTTKKLEGSIAASGRGLSPPQ 926
             EP+   T +  G    + RG  PP+
Sbjct: 148 VHEPEPTPTVETRG----TARGFQPPE 170



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)

Query: 6   AAGPGPEPEPE---PEPEPEPAPEPEPEPKP 33
           A GP  E + E   P   PEP  EPEPEP+P
Sbjct: 85  AKGPWQEADQEQQEPVGSPEPESEPEPEPEP 115


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 56/248 (22%), Positives = 84/248 (33%), Gaps = 21/248 (8%)

Query: 847  PGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPL-----EQDSAVDNALLLTQSKRFS 901
            P     +P   T PPP + P  P   +     + P      EQ+ +    +  T S++  
Sbjct: 411  PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG 470

Query: 902  EPQKLTTKKLEGSIAASG-RGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGT 960
             P    +++ E   A +G  G SPP   P      PP     +A       +   +F   
Sbjct: 471  RPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMP 530

Query: 961  HHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPC-- 1018
                 +   +   +R   + P +PP V              PVP  P+     P AP   
Sbjct: 531  VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590

Query: 1019 -----LPVKRGSP--------ASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
                 LP KR S          S T     PP   P P +   P +P ++   P L   P
Sbjct: 591  STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP 650

Query: 1066 ENTSLQEH 1073
            + T  + H
Sbjct: 651  QFTPSEAH 658



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 70/289 (24%), Positives = 102/289 (35%), Gaps = 35/289 (12%)

Query: 790  GLAPDTSKSCDPPGVTGLNKNRRSL-PVSICRSCETLEGPQT-VDTWPRSHSLDDLQVEP 847
            G  P+ S +  P   T L   R+ + PV   RS   ++ P+  +D  P       ++V P
Sbjct: 504  GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP--KVEVSP 561

Query: 848  GAEQDVPTEVTEPP-PQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKL 906
                 + T    P  P  VP  P+  T  ST   PL +      ++L   + R++     
Sbjct: 562  VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPV-PLPEKR---RSILREPTFRWTS---- 613

Query: 907  TTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPL----------EGHRKGHE 956
             T++L            PP   P      PP A    +R PL          E H K +E
Sbjct: 614  LTRELP----------PPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663

Query: 957  FEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDA 1016
               T  PLG  E  + E       P++P P    ++         PV   P  A  SP  
Sbjct: 664  SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723

Query: 1017 PCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
               P     P +         AL  + L    P   P  +PPP   ++P
Sbjct: 724  --APALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 20/101 (19%)

Query: 967  KEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSP 1026
            KEG + E+R    +  +  P   K+  +     L P P+ P    PSP  P LP    SP
Sbjct: 376  KEGEEKEERA---VAEEMMPAAEKEEAK-----LPPPPLTPPA--PSPPPP-LPPPSTSP 424

Query: 1027 ASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPEN 1067
              P  P   PP ++P PL        PS  PPP   E  E+
Sbjct: 425  PPPLCPPP-PPPVSPPPL--------PSPPPPPAQEEQEES 456



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 35/199 (17%)

Query: 878  KAQPLEQDSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAASG--------RGLSPPQCLP 929
            + +P   ++A +N  ++      SEP       L+  +   G        + L PP   P
Sbjct: 1789 REEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP-LRP 1847

Query: 930  RNYDAQPPGAKHGLARTPLEGHR-KGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQ----- 983
             +  A PP  +         G R K   +  +  PLG   GV       P  PS      
Sbjct: 1848 DSGSAPPPAPRS------FSGARIKVPNYSPSRRPLG---GVSFGPLPSPGSPSSLTHHI 1898

Query: 984  ----PPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPAL 1039
                 P  PA   R R  + L P P  P     SP     P  R  P     P+    AL
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRP--PPSRWASPPLKTSPQLRVPP-----PTSVVTAL 1951

Query: 1040 APRPLSGQAPGSPPSTRPP 1058
             P       PG  PS  PP
Sbjct: 1952 TPTSGELAPPGPAPSPPPP 1970



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 20/111 (18%)

Query: 949  EGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQP--PPVPAKKSRERLANGLHPVPMG 1006
            E   K  E E        +E + A ++ + K+P  P  PP P+            P P+ 
Sbjct: 370  EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSP-----------PPPLP 418

Query: 1007 PSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRP 1057
            P    P P   C P     P  P SP    P+  P P   +   SPP   P
Sbjct: 419  PPSTSPPPPL-CPP-----PPPPVSPPPL-PSPPPPPAQEEQEESPPPVVP 462


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 8/115 (6%)

Query: 955  HEFEGTHHPLGTKEGVDA-EQRMQPKIPSQ---PPPVPAKKSRERLANGLHPVPMGPSGA 1010
            ++ +  H  L   EG+ + +Q+  P  P+    PPP+P+       A  + PV  GP   
Sbjct: 622  NDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP 681

Query: 1011 LPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP 1065
             P P  P LP     P+S   P   PP   P   +   PG PP   PPP L+  P
Sbjct: 682  PPPPPPPPLP----PPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPP 732



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 16/37 (43%), Positives = 16/37 (43%)

Query: 4   AGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEA 40
           AG   P P P P P P P  A  P P P P    S A
Sbjct: 676 AGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPA 712


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 73/249 (29%), Positives = 93/249 (37%), Gaps = 25/249 (10%)

Query: 847  PGAEQDVPTEVTEPPPQIVPEV--PQKTTASSTKAQP-LEQDSAVDNALLLTQSKRFSEP 903
            P + Q  P  +T PP + +P +  P   TAS+    P LE         L       + P
Sbjct: 520  PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579

Query: 904  QKLTTKKLEGSIAASGRGLSPP--QCLPRN----YDAQPPGAKHGLARTPLEGHRKGHEF 957
               T   +      +   L+ P  Q LP          PP A   LA  PL+        
Sbjct: 580  PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP-PSPPA 638

Query: 958  EGTHHPLGTK--EGVDAEQRMQPKIPSQPPPVPAKKS--RERLANGLHPVPMGPSGALPS 1013
                 PL T   +  +A      + P  PPP P  ++      +  + P    PS A PS
Sbjct: 639  SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698

Query: 1014 PDAPCLPVKRGSPASPT-SPSDCPPALAPRPLSG---QAPGSPP-------STRPPPWLS 1062
              AP L V    PASP  SPS  PP  AP PL+    Q P SPP       S  PPP + 
Sbjct: 699  LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 1063 ELPENTSLQ 1071
             L     LQ
Sbjct: 759  PLLAAPPLQ 767



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 56/239 (23%), Positives = 80/239 (33%), Gaps = 18/239 (7%)

Query: 839  SLDDLQVEPGAE-QDVPTEVTEPPPQIVP--------EVPQKTTASSTKAQP-------L 882
            SL  L   P       P  +T PP Q  P        +VP   T+ S +A P       L
Sbjct: 353  SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412

Query: 883  EQDSAVDNALL-LTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPP-GAK 940
            +  +++ +  L  T S     P++        S  AS    SPP   P +  A PP    
Sbjct: 413  QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472

Query: 941  HGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGL 1000
               A +PL      H  +                 + P + +Q    P        +   
Sbjct: 473  LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532

Query: 1001 HPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
             P+   PS A P       P+      +P  P+ CP    P PL+   P +P S   PP
Sbjct: 533  PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 46/155 (29%), Positives = 63/155 (40%), Gaps = 34/155 (21%)

Query: 920  RGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTK-EGVDAEQRMQP 978
            + L PPQ  P   DA P  A   L+ +PL           T  P GTK   V        
Sbjct: 278  QALRPPQVTPPRKDAAP--ALGPLSSSPL----------ATPSPSGTKARPVPPPDNAAT 325

Query: 979  KIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPA 1038
             +P+  PP P   +         P+P+ P    PSP AP  P  +  P+ P +P    P+
Sbjct: 326  PLPATLPPSPPLAT---------PLPLAP----PSPSAP--PSLQTLPSPPATP----PS 366

Query: 1039 LAPRPLSGQAPGSPPS--TRPPPWLSELPENTSLQ 1071
             AP  ++     +PPS  T PP  +     + SLQ
Sbjct: 367  QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 46/148 (31%), Positives = 54/148 (36%), Gaps = 29/148 (19%)

Query: 923  SPPQCLPRNYDAQPPG-AKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKI- 980
            SPP   P +  A PP  A   LA  PL+                      A   M P   
Sbjct: 678  SPPASPPVSPSATPPSQAPPSLAAPPLQ----------------VPPSPPASPPMSPSAT 721

Query: 981  --PSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPA 1038
              P  PPP+ A   +   +    P PM PS A P P  P L       A P      PPA
Sbjct: 722  PPPQAPPPLAAPPLQVPPSPPASP-PMSPS-ATPPPRVPPLLA-----APPLQVPPSPPA 774

Query: 1039 LAP-RPLSGQAPGSPPSTRPPPWLSELP 1065
              P  PL+   P +PP+   PP L  LP
Sbjct: 775  SLPMSPLAKPPPQAPPALATPP-LQALP 801



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 65/310 (20%), Positives = 102/310 (32%), Gaps = 43/310 (13%)

Query: 782  QEEGRLGGGLAPDTSKSCDPPGVTGLN-KNRRSLPVSICR----------SCETLEGPQT 830
            +  G +GG   P+++    P    G + +N  S P +  R          S   +  P  
Sbjct: 60   ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119

Query: 831  VDTWPRSHSLDDLQVEPGAEQDVPT-EVTEPPPQIVPEV-PQKTTASSTKAQP----LEQ 884
                 R   L    +   AE+ V   + TE P +       ++ T+  T   P      +
Sbjct: 120  ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179

Query: 885  DSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLA 944
              A    + L +    + P+  T    +   +AS    + P    R    + P A  GL 
Sbjct: 180  SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR----RRPSAGGGLQ 235

Query: 945  RTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPP-----------PVPAKKSR 993
            R              +  PL +        R  P+ P+ P            P      R
Sbjct: 236  RPA------SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 994  ERLANGLHPVPMGPSGALPSPDA----PCLPVKRGSPASPTSPSDCPPALAPRPLSGQAP 1049
            +  A  L P+   P  A PSP      P  P    +   P +    PP   P PL+  +P
Sbjct: 290  KDAAPALGPLSSSPL-ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348

Query: 1050 GSPPSTRPPP 1059
             +PPS +  P
Sbjct: 349  SAPPSLQTLP 358



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 61/238 (25%), Positives = 75/238 (31%), Gaps = 58/238 (24%)

Query: 835  PRSHSLDDLQVEPGAEQDVPTEVTE-PPPQIVPEV--PQKTTASSTKAQPLEQDSAVDNA 891
            P S +   LQV P      P   +  PPPQ  P +  P      S  A P    SA    
Sbjct: 696  PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755

Query: 892  LLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPG-AKHGLARTPLEG 950
             +         P  L    L+          SPP  LP +  A+PP  A   LA  PL+ 
Sbjct: 756  RV---------PPLLAAPPLQVPP-------SPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 951  HRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLAN-GLHPVPMGPSG 1009
                                         +PS P   P +      A+  + P+   P  
Sbjct: 800  -----------------------------LPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 1010 ALPSPDAPCLPVKRGSPASPT--------SPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
            A P   AP L V    PASPT        +P        PR     APG PP     P
Sbjct: 831  APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888


>gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]
          Length = 173

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 23/64 (35%), Positives = 39/64 (60%)

Query: 638 VEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEY 697
           V + L  + L ++  +F+ NGY+DL+  K + + DLD + +  P HR  +L AV  L+E 
Sbjct: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65

Query: 698 DSNS 701
           D+N+
Sbjct: 66  DANA 69



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 22/86 (25%), Positives = 33/86 (38%), Gaps = 17/86 (19%)

Query: 1178 CISSVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARL 1237
            C + V +WL ++ LP YA +    G+  L     +    L   G+    H R++L A R 
Sbjct: 2    CTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRR 61

Query: 1238 FK-----------------LPPGPEA 1246
             +                  PPGP A
Sbjct: 62   LREQDANAAGLYFTLEPQPAPPGPPA 87


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 978  PKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPP 1037
            P  PS   P P   S         P P   + A PS  AP  P    +P +P + +  PP
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP--PETTAAPPTPPATTPAPP 226

Query: 1038 ALAPRPLSGQAPGSPPSTRPPPWLSELPENTS 1069
            + +  P +  AP +P +T P P  S  P  T+
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETT 258



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 33/120 (27%), Positives = 39/120 (32%), Gaps = 15/120 (12%)

Query: 963  PLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVK 1022
            P         E    P  PS     P   S         P P   + A PS  AP  P  
Sbjct: 177  PAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAP--PET 234

Query: 1023 RGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALT 1082
              +P +P+       A  P PLS  AP  P +T  PP     P  T+L        P  T
Sbjct: 235  TAAPPTPS-------ATTPAPLSSSAP--PETTAVPP----TPSATTLDPSSASAPPETT 281



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAP----GSPP----STRPPPWLSELPEN 1067
            A   PV   +P   T+    P A  P P S  AP     +PP    +T+ PP  S  PE 
Sbjct: 152  ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPET 211

Query: 1068 TS 1069
            T+
Sbjct: 212  TA 213


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 978  PKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPP 1037
            P  PS   P P   S         P P   + A PS  AP  P    +P +P + +  PP
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP--PETTAAPPTPPATTPAPP 226

Query: 1038 ALAPRPLSGQAPGSPPSTRPPPWLSELPENTS 1069
            + +  P +  AP +P +T P P  S  P  T+
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETT 258



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 33/120 (27%), Positives = 39/120 (32%), Gaps = 15/120 (12%)

Query: 963  PLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVK 1022
            P         E    P  PS     P   S         P P   + A PS  AP  P  
Sbjct: 177  PAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAP--PET 234

Query: 1023 RGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALT 1082
              +P +P+       A  P PLS  AP  P +T  PP     P  T+L        P  T
Sbjct: 235  TAAPPTPS-------ATTPAPLSSSAP--PETTAVPP----TPSATTLDPSSASAPPETT 281



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAP----GSPP----STRPPPWLSELPEN 1067
            A   PV   +P   T+    P A  P P S  AP     +PP    +T+ PP  S  PE 
Sbjct: 152  ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPET 211

Query: 1068 TS 1069
            T+
Sbjct: 212  TA 213


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 978  PKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPP 1037
            P  PS   P P   S         P P   + A PS  AP  P    +P +P + +  PP
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP--PETTAAPPTPPATTPAPP 226

Query: 1038 ALAPRPLSGQAPGSPPSTRPPPWLSELPENTS 1069
            + +  P +  AP +P +T P P  S  P  T+
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETT 258



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 33/120 (27%), Positives = 39/120 (32%), Gaps = 15/120 (12%)

Query: 963  PLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVK 1022
            P         E    P  PS     P   S         P P   + A PS  AP  P  
Sbjct: 177  PAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAP--PET 234

Query: 1023 RGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALT 1082
              +P +P+       A  P PLS  AP  P +T  PP     P  T+L        P  T
Sbjct: 235  TAAPPTPS-------ATTPAPLSSSAP--PETTAVPP----TPSATTLDPSSASAPPETT 281



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAP----GSPP----STRPPPWLSELPEN 1067
            A   PV   +P   T+    P A  P P S  AP     +PP    +T+ PP  S  PE 
Sbjct: 152  ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPET 211

Query: 1068 TS 1069
            T+
Sbjct: 212  TA 213


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 9/104 (8%)

Query: 965  GTKEGVDAEQRMQPKIPSQPPPV---------PAKKSRERLANGLHPVPMGPSGALPSPD 1015
            G  E V  E R Q  +P  PPP          P     +  +  L PVP+G +   P+P 
Sbjct: 298  GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPR 357

Query: 1016 APCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
             P  P + G P  P   +     L P P     P  PP   PPP
Sbjct: 358  GPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 7/117 (5%)

Query: 936  PPGAKHG--LARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSR 993
            PP ++ G  L R P+ G  KG        PLG        +   P     PPP P   + 
Sbjct: 317  PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATG 376

Query: 994  ERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPG 1050
                +G  P P   +G  P P  P  P    S  +  +P   PPAL P    G APG
Sbjct: 377  R---SGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPA--GGLAPG 428



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 34/145 (23%), Positives = 51/145 (35%), Gaps = 28/145 (19%)

Query: 5   GAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVM---GILDGSLGNIDD 61
           G +GP P P P     P P P P P P P +G   A   L   ++   G+  G  G    
Sbjct: 376 GRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPG--GGRGA 433

Query: 62  LAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAV 121
           L  Q                       + Q +++ K   +P S  L+   + S G   A+
Sbjct: 434 LLDQ-----------------------IRQGIQLNKTPGAPESSALQPPPQSSEGLVGAL 470

Query: 122 STPEVERKNPLHKSNSEDSSVGKGD 146
                +R   +H S+  +   G  D
Sbjct: 471 MHVMQKRSRAIHSSDEGEDQAGDED 495


>gi|140161500 ankyrin repeat and sterile alpha motif domain
           containing 1 [Homo sapiens]
          Length = 1134

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 7/87 (8%)

Query: 625 RRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTF--KLLEEEDLDELNIRDPE 682
           R++  G     +SV + L+ I L+++    L NG++D+      ++EE+DL ++ I DP+
Sbjct: 688 RQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQ 747

Query: 683 HRAVLLTAVELLQE-----YDSNSDQS 704
           HR  LL A   L +     YD NS  S
Sbjct: 748 HRRKLLQAARSLPKVKALGYDGNSPPS 774



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 2/58 (3%)

Query: 1181 SVSDWLISIGLPMYAGTLSTAGFSTLSQVPS--LSHTCLQEAGITEERHIRKLLSAAR 1236
            SV +WL SIGL  Y   L   GF  +  + S  +    L++ GI++ +H RKLL AAR
Sbjct: 700  SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAAR 757



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 635 PKSVEDLLDRINLKEHMPTFLFNGYEDLDTFK-LLEEEDLDELNIRDPEHRAVLLTAV 691
           P SV   LD + L++++ +FL +GY  +DT K L E E ++ L ++   HR  ++ ++
Sbjct: 772 PPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASL 829


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 74/312 (23%), Positives = 105/312 (33%), Gaps = 46/312 (14%)

Query: 784  EGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDL 843
            +G  G   +P  ++   P  VT L     S+  S+   C +   P      P   S   +
Sbjct: 596  KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPA-----PSDRSGPQI 650

Query: 844  QVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEP 903
                G    +P     P P   P  P K  + +  A  L   + V   +  T +   S P
Sbjct: 651  LTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP 708

Query: 904  QKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHP 963
               TT           +  SPP   P +Y   PP  K                      P
Sbjct: 709  TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK---------------------P 747

Query: 964  LGTKEGVDAEQRMQPKI--PSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPV 1021
                E   A +  +  +  P+ PPP P     + L+    P P     ++ SP+ P  P 
Sbjct: 748  EVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE-PAGP- 805

Query: 1022 KRGSP---ASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLG 1078
              GSP   +SP + S    AL  +P     PGSP    PPP        +S   H  KL 
Sbjct: 806  -SGSPELVSSPAASSSSATALQIQP-----PGSPD---PPPAPPAPAPASSAPGHVAKL- 855

Query: 1079 PALTRKVSCARG 1090
                  V C++G
Sbjct: 856  -PQKEPVGCSKG 866



 Score = 38.9 bits (89), Expect = 0.031
 Identities = 59/222 (26%), Positives = 86/222 (38%), Gaps = 40/222 (18%)

Query: 869  PQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCL 928
            P+ +TAS++   P +  S   +          S  +   T  +  S   SGR +S  +  
Sbjct: 442  PESSTASNSVVPPPQGGSGRGSP------SGGSTAEASDTLSIRSSGQLSGRSVSLRKL- 494

Query: 929  PRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVP 988
                   PP   H L       H++G        PLG       E++ QP++P +PP   
Sbjct: 495  --KRPPPPPRRTHSL-------HQRG--LAVPDGPLGLPP--KPERKQQPQLP-RPPTTG 540

Query: 989  AKKSRERLANGLHPVPMGPS-----GALP--SPDAPCLPVKRGSPASPTSPSDCPPALAP 1041
              +       G  P P  P+     G  P  S   P  P +  SP+S  S     P L P
Sbjct: 541  GSEGA-----GAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595

Query: 1042 RPLSGQAPGSPPSTRPPPWLSELPEN-TSLQEHGVKLGPALT 1082
            + L+G  P SP   +PP      PE  TSL+  G  +  +LT
Sbjct: 596  KGLAG-PPASPGKAQPPK-----PERVTSLRSPGASVSSSLT 631



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 63/239 (26%), Positives = 92/239 (38%), Gaps = 28/239 (11%)

Query: 836  RSHSLDD--LQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALL 893
            R+HSL    L V  G     P    +  PQ+ P  P    +    A P   + A      
Sbjct: 503  RTHSLHQRGLAVPDGPLGLPPKPERKQQPQL-PRPPTTGGSEGAGAAPCPPNPANSWVPG 561

Query: 894  LTQ--SKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGH 951
            L+   S+R     + T     G  + SG    PP+ L     A PP A  G A+ P    
Sbjct: 562  LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGL-----AGPP-ASPGKAQPP---- 611

Query: 952  RKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHP-VPMGPSGA 1010
             K         P     G      +     S   P P+ +S  ++   L     + P   
Sbjct: 612  -KPERVTSLRSP-----GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPK 665

Query: 1011 LPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLS--GQAPGSPPSTRPPPWLSELPEN 1067
            +P+P +P  P K  SP +P +P+   PA+ P P+S    +P SPP+  P   L+ L E+
Sbjct: 666  VPAPFSPP-PSKPRSP-NPAAPALAAPAVVPGPVSTTDASPQSPPT--PQTTLTPLQES 720



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 27/177 (15%)

Query: 860  PPPQIVPEVPQKTT--ASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAA 917
            P P + P  PQK    A S +A P+   S+  +A +  ++   +  + L++ +  G    
Sbjct: 899  PTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG---- 954

Query: 918  SGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQ 977
                  PP+  PR     PP +    A T      KG        P+  +   D ++ + 
Sbjct: 955  ------PPEAEPR-----PPQSP---ASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000

Query: 978  PKIPS---QPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTS 1031
             ++ S   Q PP   KKS +       PV   PS  +P P +P  P      A PT+
Sbjct: 1001 AELRSISEQRPPQAPKKSPKAPP----PVARKPSVGVPPPASPSYPRAEPLTAPPTN 1053


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 21/104 (20%)

Query: 516 SGQSSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSL 575
           SG S +S +T+  T+     R                     R R    F+  P + D L
Sbjct: 42  SGNSLLSSETILRTNKRGERR---------------------RRRCQVAFSYLPQNDDEL 80

Query: 576 KLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEK 619
           +LK GDII+++ +   G W G+LN K G F   ++  LS + ++
Sbjct: 81  ELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDE 124



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 24/116 (20%)

Query: 525 TVSTTDSSTSNRES-VKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDII 583
           T +T DSS +  +S  KS+D      PY                   + D L +K+GDI+
Sbjct: 214 TTATPDSSKTEMDSRTKSKDYCKVIFPYEAQ----------------NDDELTIKEGDIV 257

Query: 584 DIISKP--PMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKS 637
            +I+K    +G W G LN + G F   +V +L  D EK        R  +PP P +
Sbjct: 258 TLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEK-----EGNRPKKPPPPSA 308


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 21/104 (20%)

Query: 516 SGQSSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSL 575
           SG S +S +T+  T+     R                     R R    F+  P + D L
Sbjct: 79  SGNSLLSSETILRTNKRGERR---------------------RRRCQVAFSYLPQNDDEL 117

Query: 576 KLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEK 619
           +LK GDII+++ +   G W G+LN K G F   ++  LS + ++
Sbjct: 118 ELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDE 161



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 24/116 (20%)

Query: 525 TVSTTDSSTSNRES-VKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDII 583
           T +T DSS +  +S  KS+D      PY                   + D L +K+GDI+
Sbjct: 251 TTATPDSSKTEMDSRTKSKDYCKVIFPYEAQ----------------NDDELTIKEGDIV 294

Query: 584 DIISKP--PMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKS 637
            +I+K    +G W G LN + G F   +V +L  D EK        R  +PP P +
Sbjct: 295 TLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEK-----EGNRPKKPPPPSA 345


>gi|40807452 peroxisome proliferator-activated receptor gamma,
            coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 71/278 (25%), Positives = 93/278 (33%), Gaps = 78/278 (28%)

Query: 841  DDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRF 900
            D   V+P     VP     PP   VP  P     +     P +  + VD  L+     R 
Sbjct: 638  DSAAVDPAV---VPISDNLPPVDAVPSGPAPVDLALVDPVPNDL-TPVDPVLV---KSRP 690

Query: 901  SEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGA-----KHGLARTPLEGHRKGH 955
            ++P++           +S  G S PQ L  +    PP       K  +    +E      
Sbjct: 691  TDPRR--------GAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSAT 742

Query: 956  EFEGTHHPLGTKEGVDAEQRMQ---------------PKIPSQP-----------PPVPA 989
              E    PL   E     Q+ Q               P +P  P           PP PA
Sbjct: 743  THEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPA 802

Query: 990  KKSRERLANG----LHPVPMGPSGALPSPDAPCL------------------------PV 1021
            KK+  + +      +  VP+GPS A PSP+ P                          PV
Sbjct: 803  KKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPV 862

Query: 1022 KRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPP 1059
            +  SPA PT PS    A  P P  G   G PPS  PPP
Sbjct: 863  QSVSPAVPTPPS--MSAALPFPAGGL--GMPPSLPPPP 896



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 77/341 (22%), Positives = 112/341 (32%), Gaps = 68/341 (19%)

Query: 789  GGLAPDT---SKSCDPPG--VTGLNKNRRSLPVSICRSCETLEG---PQTVDTWPRSHSL 840
            GG AP     S+S DPP   +  + +   SL +    S  T E    P ++  + R    
Sbjct: 703  GGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQ 762

Query: 841  DDLQVEPGAEQ----------DVPTEVTEPPPQIVPEVPQKTTASSTKAQ-PLEQDSAVD 889
               + E  + Q          + PT + + P  ++P  P K TA     + PLE      
Sbjct: 763  RQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEIC---- 818

Query: 890  NALLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLE 949
              + +  S     P+   +K     +A+S     P Q +P      PP      A     
Sbjct: 819  -LVPVGPSPASPSPEPPVSKP----VASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPP 873

Query: 950  GHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPM---- 1005
                   F     P G   G+     + P  P QPP +P            H  P+    
Sbjct: 874  SMSAALPF-----PAG---GLGMPPSLPPP-PLQPPSLPLSMGPVLPDPFTHYAPLPSWP 924

Query: 1006 -----GPSGALPSPDAPCLPVKRGSPASPTSPSDC--PPALAPRPLS-----------GQ 1047
                  PSG    P  P +P+  G+P +   P  C  P A  P P+S           G 
Sbjct: 925  CYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGW 984

Query: 1048 APGS---------PPSTRPPPWLSELPENTSLQEHGVKLGP 1079
             PG          PP   PP  +        ++  G   GP
Sbjct: 985  GPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGP 1025


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 15/102 (14%)

Query: 552 RGPFCGRARVH------------TDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLN 599
           R P C R R H             +F+ SP   D LKL+ G+I+++I +   G W+G  N
Sbjct: 67  RRPRCARRRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKN 126

Query: 600 NKVGTFKFIYVDVLSEDEE---KPKRPTRRRRKGRPPQPKSV 638
            ++G F   +V++L         P  P+      RPP+  S+
Sbjct: 127 GQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSL 168


>gi|239756307 PREDICTED: similar to ubiquitin-associated protein 1
            (predicted) [Homo sapiens]
          Length = 290

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 59/223 (26%), Positives = 80/223 (35%), Gaps = 56/223 (25%)

Query: 915  IAASGRGLSPPQCLPRNYDAQPPG------AKHGLA------RTPLEGHRKGHEFEGTHH 962
            + A+G+G SP QC      + PP        +HGLA      R P  GH++  E EG   
Sbjct: 53   VEAAGQGPSPYQCGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQERPEEEGEDE 112

Query: 963  PLGTK--EGVDAEQRMQPKIPSQPPP--------------VPAKKSRERLANG------- 999
               +   E   A   +QP  P+ P P              +    +R RL+ G       
Sbjct: 113  AEASSGSEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPR 172

Query: 1000 -------------LHPVP-MGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLS 1045
                         L P P   P  A P   AP  P    SP  P++    PP  + +P  
Sbjct: 173  ALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTV 232

Query: 1046 G----QAPGSPPSTRPPP--WLSELPENTSLQEHGVKLGPALT 1082
                  AP  PP + P P  W+S    +     H + L P LT
Sbjct: 233  AVRILPAPPRPPISSPGPIIWVSSPARSLGPLLHAL-LHPPLT 274


>gi|239750857 PREDICTED: similar to ubiquitin-associated protein 1
            (predicted) [Homo sapiens]
          Length = 290

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 59/223 (26%), Positives = 80/223 (35%), Gaps = 56/223 (25%)

Query: 915  IAASGRGLSPPQCLPRNYDAQPPG------AKHGLA------RTPLEGHRKGHEFEGTHH 962
            + A+G+G SP QC      + PP        +HGLA      R P  GH++  E EG   
Sbjct: 53   VEAAGQGPSPYQCGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQERPEEEGEDE 112

Query: 963  PLGTK--EGVDAEQRMQPKIPSQPPP--------------VPAKKSRERLANG------- 999
               +   E   A   +QP  P+ P P              +    +R RL+ G       
Sbjct: 113  AEASSGSEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPR 172

Query: 1000 -------------LHPVP-MGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLS 1045
                         L P P   P  A P   AP  P    SP  P++    PP  + +P  
Sbjct: 173  ALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTV 232

Query: 1046 G----QAPGSPPSTRPPP--WLSELPENTSLQEHGVKLGPALT 1082
                  AP  PP + P P  W+S    +     H + L P LT
Sbjct: 233  AVRILPAPPRPPISSPGPIIWVSSPARSLGPLLHAL-LHPPLT 274


>gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 59/223 (26%), Positives = 80/223 (35%), Gaps = 56/223 (25%)

Query: 915  IAASGRGLSPPQCLPRNYDAQPPG------AKHGLA------RTPLEGHRKGHEFEGTHH 962
            + A+G+G SP QC      + PP        +HGLA      R P  GH++  E EG   
Sbjct: 53   VEAAGQGPSPYQCGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQERPEEEGEDE 112

Query: 963  PLGTK--EGVDAEQRMQPKIPSQPPP--------------VPAKKSRERLANG------- 999
               +   E   A   +QP  P+ P P              +    +R RL+ G       
Sbjct: 113  AEASSGSEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPR 172

Query: 1000 -------------LHPVP-MGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLS 1045
                         L P P   P  A P   AP  P    SP  P++    PP  + +P  
Sbjct: 173  ALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTV 232

Query: 1046 G----QAPGSPPSTRPPP--WLSELPENTSLQEHGVKLGPALT 1082
                  AP  PP + P P  W+S    +     H + L P LT
Sbjct: 233  AVRILPAPPRPPISSPGPIIWVSSPARSLGPLLHAL-LHPPLT 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,981,809
Number of Sequences: 37866
Number of extensions: 3502487
Number of successful extensions: 38415
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 315
Number of HSP's successfully gapped in prelim test: 1041
Number of HSP's that attempted gapping in prelim test: 23347
Number of HSP's gapped (non-prelim): 13452
length of query: 1247
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1133
effective length of database: 13,930,794
effective search space: 15783589602
effective search space used: 15783589602
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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