Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4557395

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557395 carbonic anhydrase II [Homo sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557395 carbonic anhydrase II [Homo sapiens]                       548   e-156
gi|38348436 carbonic anhydrase XIII [Homo sapiens]                    332   2e-91
gi|4885099 carbonic anhydrase III [Homo sapiens]                      329   1e-90
gi|192447434 carbonic anhydrase I [Homo sapiens]                      323   9e-89
gi|192447432 carbonic anhydrase I [Homo sapiens]                      323   9e-89
gi|192447430 carbonic anhydrase I [Homo sapiens]                      323   9e-89
gi|4502517 carbonic anhydrase I [Homo sapiens]                        323   9e-89
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]            314   4e-86
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ...   283   1e-76
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ...   264   7e-71
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]           246   2e-65
gi|22027500 carbonic anhydrase VIII [Homo sapiens]                    200   1e-51
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]            161   6e-40
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap...   154   7e-38
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi...   154   7e-38
gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]            151   6e-37
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]           145   4e-35
gi|130979954 carbonic anhydrase X [Homo sapiens]                      138   5e-33
gi|130979679 carbonic anhydrase X [Homo sapiens]                      138   5e-33
gi|9910366 carbonic anhydrase X [Homo sapiens]                        138   5e-33
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]             135   4e-32
gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]             123   2e-28
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...   111   6e-25
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   109   3e-24
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]           39   0.005
gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]           39   0.005
gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]           39   0.005
gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]           37   0.013
gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]           36   0.038
gi|38505213 YTH domain containing 2 [Homo sapiens]                     31   1.2  

>gi|4557395 carbonic anhydrase II [Homo sapiens]
          Length = 260

 Score =  548 bits (1412), Expect = e-156
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60
           MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
Sbjct: 1   MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60

Query: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120
           NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
Sbjct: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120

Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
Sbjct: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
           RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240

Query: 241 VDNWRPAQPLKNRQIKASFK 260
           VDNWRPAQPLKNRQIKASFK
Sbjct: 241 VDNWRPAQPLKNRQIKASFK 260


>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
          Length = 262

 Score =  332 bits (851), Expect = 2e-91
 Identities = 155/256 (60%), Positives = 192/256 (75%), Gaps = 1/256 (0%)

Query: 5   WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64
           WGY +HNGP HW + FPIA G++QSP++I T   KYD SL+PLS+ YD +++  I N+GH
Sbjct: 6   WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 65

Query: 65  AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124
           +FNV+FDD+++K+VL+GGPL G+YRL Q H HWGS D  GSEH VD   YAAELH+VHWN
Sbjct: 66  SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 125

Query: 125 T-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGL 183
           + KY  F +A  +PDGLAVLG+FL++G     LQK+ D LDSIK KGK   FTNFD   L
Sbjct: 126 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 185

Query: 184 LPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243
           LP S DYWTYPGSLT PPLLE VTWIVLK+PI++SS+Q+ KFR L    EGE    +V N
Sbjct: 186 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 245

Query: 244 WRPAQPLKNRQIKASF 259
            RP QPLK R+++ASF
Sbjct: 246 HRPPQPLKGRKVRASF 261


>gi|4885099 carbonic anhydrase III [Homo sapiens]
          Length = 260

 Score =  329 bits (844), Expect = 1e-90
 Identities = 152/260 (58%), Positives = 186/260 (71%)

Query: 1   MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60
           M+  WGY  HNGP+HWH+ FP AKGE QSPV++ T   ++DPSL+P SVSYD  ++  IL
Sbjct: 1   MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60

Query: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120
           NNG    V FDD+ D+++L+GGPL G YRL QFH HWGS D  GSEHTVD  KYAAELHL
Sbjct: 61  NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120

Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           VHWN KY  F +A++Q DG+AV+GIFLK+G      Q  +D LD IKTKGK A FT FDP
Sbjct: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
             L P   DYWTY GS TTPP  EC+ W++LKEP++VSS+Q+ K R L  + E EP   +
Sbjct: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240

Query: 241 VDNWRPAQPLKNRQIKASFK 260
           V NWRP QP+ NR ++ASFK
Sbjct: 241 VSNWRPPQPINNRVVRASFK 260


>gi|192447434 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  323 bits (828), Expect = 9e-89
 Identities = 156/259 (60%), Positives = 188/259 (72%), Gaps = 1/259 (0%)

Query: 2   SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61
           S  WGY   NGPE W K +PIA G  QSPVDI T   K+D SLKP+SVSY+ AT+  I+N
Sbjct: 3   SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIIN 62

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121
            GH+F+V F+D+ +++VLKGGP   +YRL QFHFHWGS +  GSEHTVD  KY+AELH+ 
Sbjct: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122

Query: 122 HWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           HWN+ KY    +A  + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP
Sbjct: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
             LLP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L  N EG+    M
Sbjct: 183 STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPM 242

Query: 241 VDNWRPAQPLKNRQIKASF 259
             N RP QPLK R ++ASF
Sbjct: 243 QHNNRPTQPLKGRTVRASF 261


>gi|192447432 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  323 bits (828), Expect = 9e-89
 Identities = 156/259 (60%), Positives = 188/259 (72%), Gaps = 1/259 (0%)

Query: 2   SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61
           S  WGY   NGPE W K +PIA G  QSPVDI T   K+D SLKP+SVSY+ AT+  I+N
Sbjct: 3   SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIIN 62

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121
            GH+F+V F+D+ +++VLKGGP   +YRL QFHFHWGS +  GSEHTVD  KY+AELH+ 
Sbjct: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122

Query: 122 HWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           HWN+ KY    +A  + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP
Sbjct: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
             LLP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L  N EG+    M
Sbjct: 183 STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPM 242

Query: 241 VDNWRPAQPLKNRQIKASF 259
             N RP QPLK R ++ASF
Sbjct: 243 QHNNRPTQPLKGRTVRASF 261


>gi|192447430 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  323 bits (828), Expect = 9e-89
 Identities = 156/259 (60%), Positives = 188/259 (72%), Gaps = 1/259 (0%)

Query: 2   SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61
           S  WGY   NGPE W K +PIA G  QSPVDI T   K+D SLKP+SVSY+ AT+  I+N
Sbjct: 3   SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIIN 62

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121
            GH+F+V F+D+ +++VLKGGP   +YRL QFHFHWGS +  GSEHTVD  KY+AELH+ 
Sbjct: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122

Query: 122 HWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           HWN+ KY    +A  + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP
Sbjct: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
             LLP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L  N EG+    M
Sbjct: 183 STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPM 242

Query: 241 VDNWRPAQPLKNRQIKASF 259
             N RP QPLK R ++ASF
Sbjct: 243 QHNNRPTQPLKGRTVRASF 261


>gi|4502517 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  323 bits (828), Expect = 9e-89
 Identities = 156/259 (60%), Positives = 188/259 (72%), Gaps = 1/259 (0%)

Query: 2   SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61
           S  WGY   NGPE W K +PIA G  QSPVDI T   K+D SLKP+SVSY+ AT+  I+N
Sbjct: 3   SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIIN 62

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121
            GH+F+V F+D+ +++VLKGGP   +YRL QFHFHWGS +  GSEHTVD  KY+AELH+ 
Sbjct: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122

Query: 122 HWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180
           HWN+ KY    +A  + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP
Sbjct: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182

Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240
             LLP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L  N EG+    M
Sbjct: 183 STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPM 242

Query: 241 VDNWRPAQPLKNRQIKASF 259
             N RP QPLK R ++ASF
Sbjct: 243 QHNNRPTQPLKGRTVRASF 261


>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
          Length = 264

 Score =  314 bits (805), Expect = 4e-86
 Identities = 146/259 (56%), Positives = 185/259 (71%), Gaps = 1/259 (0%)

Query: 3   HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNN 62
           H WGYG+ +GP HWHK +PIA+G+RQSP++I +  A Y PSL+PL +SY+   SL I NN
Sbjct: 5   HGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 64

Query: 63  GHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122
           GH+  V+F+DS D+ V+ GGPL+G YRL QFHFHWG     GSEHTVD K + +ELHLVH
Sbjct: 65  GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 124

Query: 123 WNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPR 181
           WN  KY  FG+A   PDGLAV+G+FL+ G   P + ++ D L  ++ KG  A F+ F+P+
Sbjct: 125 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPK 184

Query: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV 241
            LLP S  YWTYPGSLTTPPL E VTWIVL+EPI +S  Q+ KFR L F  E +    MV
Sbjct: 185 CLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMV 244

Query: 242 DNWRPAQPLKNRQIKASFK 260
           +N+RP QPLK R +KASF+
Sbjct: 245 NNFRPPQPLKGRVVKASFR 263


>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
           sapiens]
          Length = 317

 Score =  283 bits (724), Expect = 1e-76
 Identities = 135/246 (54%), Positives = 176/246 (71%), Gaps = 1/246 (0%)

Query: 16  WHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQD 75
           W     +  G+RQSP++I    + YDP LKPL++SYD AT L + NNG++F VEF+DS D
Sbjct: 52  WESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTD 111

Query: 76  KAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAV 134
           K+V+KGGPL+  YRL QFHFHWG++D  GSEHTVD K + AELHLVHWN  ++ +F  A 
Sbjct: 112 KSVIKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAA 171

Query: 135 QQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYP 194
            + +GLAV+G+FLK+G     LQK+VD L SIK K    +F +FDP  L+P   DYWTY 
Sbjct: 172 LEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYS 231

Query: 195 GSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQ 254
           GSLTTPPL E VTWI+ K+P+ V  +Q+ +FR L F  EGE E+ MVDN+RP QPL NR 
Sbjct: 232 GSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRT 291

Query: 255 IKASFK 260
           +++SF+
Sbjct: 292 VRSSFR 297


>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
           sapiens]
          Length = 305

 Score =  264 bits (674), Expect = 7e-71
 Identities = 130/246 (52%), Positives = 169/246 (68%), Gaps = 1/246 (0%)

Query: 16  WHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQD 75
           W     +  G RQSP++I    + YDP LKPL VSY+ A+ L I N G+ F VEFDD+ +
Sbjct: 52  WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATE 111

Query: 76  KAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNT-KYGDFGKAV 134
            + + GGPL+  YRL QFHFHWG+++  GSEHTVD   Y AELHLVHWN+ KY ++ +AV
Sbjct: 112 ASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAV 171

Query: 135 QQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYP 194
              +GLAV+G+FLK+G+    LQ++VD+L  IK K   A    FDP  LLP   DYWTY 
Sbjct: 172 VGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYA 231

Query: 195 GSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQ 254
           GSLTTPPL E VTWI+ KEP+ V+  Q+  FR L F+  GE E++MV+N+RP QPL NR+
Sbjct: 232 GSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRK 291

Query: 255 IKASFK 260
           + ASF+
Sbjct: 292 VWASFQ 297


>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
          Length = 208

 Score =  246 bits (627), Expect = 2e-65
 Identities = 117/206 (56%), Positives = 145/206 (70%), Gaps = 1/206 (0%)

Query: 56  SLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYA 115
           SL I NNGH+  V+F+DS D+ V+ GGPL+G YRL QFHFHWG     GSEHTVD K + 
Sbjct: 2   SLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFP 61

Query: 116 AELHLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSAD 174
           +ELHLVHWN K Y  FG+A   PDGLAV+G+FL+ G   P + ++ D L  ++ KG  A 
Sbjct: 62  SELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQ 121

Query: 175 FTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEG 234
           F+ F+P+ LLP S  YWTYPGSLTTPPL E VTWIVL+EPI +S  Q+ KFR L F  E 
Sbjct: 122 FSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSED 181

Query: 235 EPEELMVDNWRPAQPLKNRQIKASFK 260
           +    MV+N+RP QPLK R +KASF+
Sbjct: 182 DERIHMVNNFRPPQPLKGRVVKASFR 207


>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
          Length = 290

 Score =  200 bits (508), Expect = 1e-51
 Identities = 110/268 (41%), Positives = 162/268 (60%), Gaps = 18/268 (6%)

Query: 5   WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKP--LSVSYDQATSLRILNN 62
           WGY    G E W   FP A GE QSP+++++  A+YDPSL    LS +Y       + N+
Sbjct: 29  WGY--EEGVE-WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTND 85

Query: 63  GHAFNVEFDDSQDKAVLKGGPLDG--TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120
           GH   V     + K+VL GGPL     + L +  FHWG  + +GSEHTV+ K +  ELHL
Sbjct: 86  GHTIQVIL---KSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHL 142

Query: 121 VHWN-TKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
           +HWN T +G   +AV +P G+A++ +F+++G    GL+ V ++L  I+ KGKS     F+
Sbjct: 143 IHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 202

Query: 180 PRGLLPESL--DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP- 236
           P  LLP+ L  DYW Y GSLT PP  E VTWI+ + P+++S  Q+ +FR+L  + +G   
Sbjct: 203 PNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAEL 262

Query: 237 ----EELMVDNWRPAQPLKNRQIKASFK 260
               + ++ DN+RP QPL +R I+A+F+
Sbjct: 263 VEGCDGILGDNFRPTQPLSDRVIRAAFQ 290


>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
          Length = 337

 Score =  161 bits (407), Expect = 6e-40
 Identities = 96/263 (36%), Positives = 136/263 (51%), Gaps = 12/263 (4%)

Query: 4   HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSV-SYDQATS--LRIL 60
           HW Y   +G +HW   +P      QSP+DI T +  +DP L  L    YDQ  +  L + 
Sbjct: 21  HWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLH 80

Query: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQG-SEHTVDKKKYAAELH 119
           NNGH   +    +     L  G L   Y   Q H HWG     G SEH ++ +   AELH
Sbjct: 81  NNGHTVQLSLPST-----LYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELH 135

Query: 120 LVHWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKP-GLQKVVDVLDSIKTKGKSADFTN 177
           +VH+++  Y    +A ++P GLAVLGI ++VG  K    + ++  L  ++ K +      
Sbjct: 136 IVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPP 195

Query: 178 FDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP 236
           F+ R LLP+ L  Y+ Y GSLTTPP  + V W V      +S EQ+ K +   F+ E EP
Sbjct: 196 FNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEP 255

Query: 237 EELMVDNWRPAQPLKNRQIKASF 259
            +L+V N+R  QPL  R + ASF
Sbjct: 256 SKLLVQNYRALQPLNQRMVFASF 278


>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
           sapiens]
          Length = 343

 Score =  154 bits (389), Expect = 7e-38
 Identities = 94/264 (35%), Positives = 137/264 (51%), Gaps = 15/264 (5%)

Query: 5   WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSLRIL--N 61
           W Y   +G   W K +P   G  QSP+D+ +   +YD SL PL    Y+ + + + L  N
Sbjct: 32  WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSL-DGQGSEHTVDKKKYAAELHL 120
           NGH+  +          ++G  L   Y   Q H HWG+  D  GSEHTV  + +AAELH+
Sbjct: 92  NGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146

Query: 121 VHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
           VH+N+  Y D   A  + +GLAVL + +++GS  P   K+   L  +K KG+ A    F+
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206

Query: 180 PRGLLPE-SLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNF---NGEGE 235
              LLPE + +Y+ Y GSLTTPP    V W V + P+ +S EQ+L      +     +  
Sbjct: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266

Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259
           P E M++N+R  Q    R +  SF
Sbjct: 267 PRE-MINNFRQVQKFDERLVYTSF 289


>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
           sapiens]
          Length = 354

 Score =  154 bits (389), Expect = 7e-38
 Identities = 94/264 (35%), Positives = 137/264 (51%), Gaps = 15/264 (5%)

Query: 5   WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSLRIL--N 61
           W Y   +G   W K +P   G  QSP+D+ +   +YD SL PL    Y+ + + + L  N
Sbjct: 32  WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSL-DGQGSEHTVDKKKYAAELHL 120
           NGH+  +          ++G  L   Y   Q H HWG+  D  GSEHTV  + +AAELH+
Sbjct: 92  NGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146

Query: 121 VHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
           VH+N+  Y D   A  + +GLAVL + +++GS  P   K+   L  +K KG+ A    F+
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206

Query: 180 PRGLLPE-SLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNF---NGEGE 235
              LLPE + +Y+ Y GSLTTPP    V W V + P+ +S EQ+L      +     +  
Sbjct: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266

Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259
           P E M++N+R  Q    R +  SF
Sbjct: 267 PRE-MINNFRQVQKFDERLVYTSF 289


>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
          Length = 308

 Score =  151 bits (381), Expect = 6e-37
 Identities = 93/264 (35%), Positives = 142/264 (53%), Gaps = 17/264 (6%)

Query: 5   WGYGKHNGPE-HWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YD-QATSLRILN 61
           W Y +    E HW + +P   G+RQSP+++     +Y+PSLK L+++ Y+ QA    ++N
Sbjct: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGT-YRLIQFHFHWGSLDGQ--GSEHTVDKKKYAAEL 118
           NGH   +    +    V      DGT Y   Q HFHWG    +  GSEHTVD  ++  E+
Sbjct: 83  NGHTVQISLPSTMRMTVA-----DGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137

Query: 119 HLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPG--LQKVVDVLDSIKTKGKSADFT 176
           H+VH+N+KY  +  A   PDGLAVL  F++V +          +  L +IK  G+    T
Sbjct: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197

Query: 177 NFDPRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE 235
             D + +LP +L  Y+TY GSLTTPP  E V W VL + + +S  QV K      +    
Sbjct: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLD---H 254

Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259
             + + +++R  QPL +R ++++F
Sbjct: 255 RNKTIHNDYRRTQPLNHRVVESNF 278


>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
          Length = 459

 Score =  145 bits (365), Expect = 4e-35
 Identities = 90/261 (34%), Positives = 132/261 (50%), Gaps = 15/261 (5%)

Query: 4   HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQAT---SLRIL 60
           HW YG   G   W +  P   G  QSPVDI    A + P+L+PL +   Q      LR+ 
Sbjct: 140 HWRYG---GDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLR 196

Query: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120
           NNGH+  +      + A+  G      YR +Q H HWG+    GSEHTV+  ++ AE+H+
Sbjct: 197 NNGHSVQLTLPPGLEMALGPGRE----YRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHV 252

Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-SAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
           VH +T +    +A+ +P GLAVL  FL+ G       ++++  L+ I  +G        D
Sbjct: 253 VHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 312

Query: 180 PRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238
              LLP     Y+ Y GSLTTPP  + V W V  + + +S++Q+     L+    G  + 
Sbjct: 313 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQL---HTLSDTLWGPGDS 369

Query: 239 LMVDNWRPAQPLKNRQIKASF 259
            +  N+R  QPL  R I+ASF
Sbjct: 370 RLQLNFRATQPLNGRVIEASF 390


>gi|130979954 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  138 bits (347), Expect = 5e-33
 Identities = 80/239 (33%), Positives = 135/239 (56%), Gaps = 6/239 (2%)

Query: 25  GERQSPVDIDTHTAKYDPSLKPLSVSYD-QATSLRILNNGHAFNVEFDDSQDKAVLKGGP 83
           G+RQSPV+I+T    +DP L PL ++   +  S  + N G   ++  D  +    + GGP
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLD-KEHLVNISGGP 121

Query: 84  LDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPDGLAV 142
           +  ++RL +   H+GS D QGSEH ++ + ++ E+ L+H+N + Y +  +A + P+GL V
Sbjct: 122 MTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVV 181

Query: 143 LGIFLKVG-SAKPGLQKVV--DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTT 199
           + IF+KV  S+ P L +++  D +  I  K  +      +   L PE+  + TY GS+T 
Sbjct: 182 VSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTI 241

Query: 200 PPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKAS 258
           PP  E  +WI++ +P+ ++  Q+   R L+ N   +    M DN+RP QPL NR I+ +
Sbjct: 242 PPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|130979679 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  138 bits (347), Expect = 5e-33
 Identities = 80/239 (33%), Positives = 135/239 (56%), Gaps = 6/239 (2%)

Query: 25  GERQSPVDIDTHTAKYDPSLKPLSVSYD-QATSLRILNNGHAFNVEFDDSQDKAVLKGGP 83
           G+RQSPV+I+T    +DP L PL ++   +  S  + N G   ++  D  +    + GGP
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLD-KEHLVNISGGP 121

Query: 84  LDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPDGLAV 142
           +  ++RL +   H+GS D QGSEH ++ + ++ E+ L+H+N + Y +  +A + P+GL V
Sbjct: 122 MTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVV 181

Query: 143 LGIFLKVG-SAKPGLQKVV--DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTT 199
           + IF+KV  S+ P L +++  D +  I  K  +      +   L PE+  + TY GS+T 
Sbjct: 182 VSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTI 241

Query: 200 PPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKAS 258
           PP  E  +WI++ +P+ ++  Q+   R L+ N   +    M DN+RP QPL NR I+ +
Sbjct: 242 PPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|9910366 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  138 bits (347), Expect = 5e-33
 Identities = 80/239 (33%), Positives = 135/239 (56%), Gaps = 6/239 (2%)

Query: 25  GERQSPVDIDTHTAKYDPSLKPLSVSYD-QATSLRILNNGHAFNVEFDDSQDKAVLKGGP 83
           G+RQSPV+I+T    +DP L PL ++   +  S  + N G   ++  D  +    + GGP
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLD-KEHLVNISGGP 121

Query: 84  LDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPDGLAV 142
           +  ++RL +   H+GS D QGSEH ++ + ++ E+ L+H+N + Y +  +A + P+GL V
Sbjct: 122 MTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVV 181

Query: 143 LGIFLKVG-SAKPGLQKVV--DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTT 199
           + IF+KV  S+ P L +++  D +  I  K  +      +   L PE+  + TY GS+T 
Sbjct: 182 VSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTI 241

Query: 200 PPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKAS 258
           PP  E  +WI++ +P+ ++  Q+   R L+ N   +    M DN+RP QPL NR I+ +
Sbjct: 242 PPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
          Length = 328

 Score =  135 bits (340), Expect = 4e-32
 Identities = 86/243 (35%), Positives = 138/243 (56%), Gaps = 10/243 (4%)

Query: 23  AKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLR--ILNNGHAFNVEFDDSQDKAV-L 79
           A G+RQSPVD++     YDP L PL +S      LR  + N G   +V F  +    V +
Sbjct: 63  AVGKRQSPVDVELKRVLYDPFLPPLRLSTG-GEKLRGTLYNTGR--HVSFLPAPRPVVNV 119

Query: 80  KGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPD 138
            GGPL  ++RL +    +G+ DG GSEH ++ + ++AE+ L+H+N + YG+F  A + P+
Sbjct: 120 SGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPN 179

Query: 139 GLAVLGIFLKVGS-AKPGLQKVV--DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPG 195
           GLA+L +F+ V S + P L +++  D +  I  K  +    +     L PES  + TY G
Sbjct: 180 GLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQG 239

Query: 196 SLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQI 255
           SL+TPP  E VTWI++   ++++S Q+   R L+ N   +  + +  N RP QPL +R +
Sbjct: 240 SLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRAL 299

Query: 256 KAS 258
           + +
Sbjct: 300 RGN 302


>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
          Length = 312

 Score =  123 bits (308), Expect = 2e-28
 Identities = 91/265 (34%), Positives = 129/265 (48%), Gaps = 18/265 (6%)

Query: 4   HWGYGKHNGPEHWHKDFPIAKG-----ERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSL 57
           HW Y       ++    P+  G     +RQSP++I T  AK D  L     S YD+  + 
Sbjct: 22  HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81

Query: 58  RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117
            + NNGH+  +  ++   KA + GG L   Y+  Q H HW  L  +GSEH++D + +A E
Sbjct: 82  TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138

Query: 118 LHLVHWNTKYGDFG-KAVQQP-DGLAVLGIFLKVGS-AKPGLQKVVDVLDSIKTKGKSAD 174
           +H+VH   K      K  Q P D +AVL   ++ G+    G Q +V+ L +I     S  
Sbjct: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198

Query: 175 FTNFDPRGLLPES---LDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKF-RKLNF 230
                   LLP+      Y+ Y GSLTTP   E V W V +EPI +  EQ+L F +KL +
Sbjct: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258

Query: 231 NGEGEPEELMVDNWRPAQPLKNRQI 255
             + E    M DN RP Q L  R +
Sbjct: 259 --DKEQTVSMKDNVRPLQQLGQRTV 281


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
           precursor [Homo sapiens]
          Length = 2315

 Score =  111 bits (278), Expect = 6e-25
 Identities = 78/266 (29%), Positives = 135/266 (50%), Gaps = 14/266 (5%)

Query: 5   WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLR---ILN 61
           W Y      ++W K +P     +QSP++ID    + + +LK L       TSL    I N
Sbjct: 38  WSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHN 97

Query: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWG--SLDGQGSEHTVDKKKYAAELH 119
            G    VE + + D  V  GG  +  ++  +  FHWG  ++   GSEH+++ +K+  E+ 
Sbjct: 98  TGKT--VEINLTNDYRV-SGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQ 154

Query: 120 LVHWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKP-GLQKVVDVLDSIKTKGKSADFTN 177
           +  ++  ++  F +AV+    L  L I  +VG+ +    + ++D ++S+   GK A    
Sbjct: 155 IYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDP 214

Query: 178 FDPRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK---LNFNGE 233
           F    LLP S D Y+ Y GSLT+PP  + V WIV K+ +S+S  Q+  F +   +  +G 
Sbjct: 215 FILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGY 274

Query: 234 GEPEELMVDNWRPAQPLKNRQIKASF 259
               + + +N+R  Q   +RQ+ +S+
Sbjct: 275 VMLMDYLQNNFREQQYKFSRQVFSSY 300


>gi|194097398 protein tyrosine phosphatase, receptor type, G
           precursor [Homo sapiens]
          Length = 1445

 Score =  109 bits (272), Expect = 3e-24
 Identities = 77/266 (28%), Positives = 122/266 (45%), Gaps = 15/266 (5%)

Query: 4   HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSLR--IL 60
           +W Y    GPEHW        G  QSP+DI    A+     + L +  +D  +S +  + 
Sbjct: 59  YWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMK 118

Query: 61  NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQ-GSEHTVDKKKYAAELH 119
           N G    +   D      + G  L G ++  +  FHWG  +G  GSEH+++ +++  E+ 
Sbjct: 119 NTGKTVAILLKDDY---FVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQ 175

Query: 120 LVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSA-KPGLQKVVDVLDSIKTKGKSADFTN 177
           +  +N   +  F  A+ +   +  + IF +V       L  ++  L  +    K      
Sbjct: 176 IFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDP 235

Query: 178 FDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP 236
           F  R LLP SL  Y+ Y GSLTTPP  E V WIV + P+ +S  Q+  F  + F  E + 
Sbjct: 236 FVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSI-FTTEQQD 294

Query: 237 E----ELMVDNWRPAQPLKNRQIKAS 258
                E + +N+RP Q L +R +  S
Sbjct: 295 HVKSVEYLRNNFRPQQRLHDRVVSKS 320


>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 26/130 (20%)

Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-----------------SAKPGLQK 158
           +++H+VH NTKY    +A +  DGL       +                   +   GL+K
Sbjct: 21  SKMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLRK 80

Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218
           V + ++ + T         F    + P +  Y  + GSLT P     V W V ++PI + 
Sbjct: 81  VPEPVNLMST---------FPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIR 131

Query: 219 SEQVLKFRKL 228
             Q+  F  L
Sbjct: 132 WVQMTLFYTL 141


>gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 26/130 (20%)

Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-----------------SAKPGLQK 158
           +++H+VH NTKY    +A +  DGL       +                   +   GL+K
Sbjct: 21  SKMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLRK 80

Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218
           V + ++ + T         F    + P +  Y  + GSLT P     V W V ++PI + 
Sbjct: 81  VPEPVNLMST---------FPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIR 131

Query: 219 SEQVLKFRKL 228
             Q+  F  L
Sbjct: 132 WVQMTLFYTL 141


>gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 26/130 (20%)

Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-----------------SAKPGLQK 158
           +++H+VH NTKY    +A +  DGL       +                   +   GL+K
Sbjct: 21  SKMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLRK 80

Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218
           V + ++ + T         F    + P +  Y  + GSLT P     V W V ++PI + 
Sbjct: 81  VPEPVNLMST---------FPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIR 131

Query: 219 SEQVLKFRKL 228
             Q+  F  L
Sbjct: 132 WVQMTLFYTL 141


>gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 37.4 bits (85), Expect = 0.013
 Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 26/127 (20%)

Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-----------------SAKPGLQK 158
           +++H+VH NTKY    +A +  DGL       +                   +   GL+K
Sbjct: 21  SKMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPCTWSPSQEQDCSNTNFCAIVSGLRK 80

Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218
           V + ++ + T         F    + P +  Y  + GSLT P     V W V ++PI + 
Sbjct: 81  VPEPVNLMST---------FLLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIR 131

Query: 219 SEQVLKF 225
             Q+  F
Sbjct: 132 WVQMTLF 138


>gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 35.8 bits (81), Expect = 0.038
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 26/127 (20%)

Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-----------------SAKPGLQK 158
           +++H+VH NTKY    +A +  DGL       +                   +   GL+K
Sbjct: 21  SKMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLRK 80

Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218
           V + ++   T         F    + P +  Y  + GSLT P     V W V ++PI + 
Sbjct: 81  VPEPVNLRST---------FLLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIR 131

Query: 219 SEQVLKF 225
             Q+  F
Sbjct: 132 WVQMTLF 138


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 6/75 (8%)

Query: 110 DKKKYAAELH-----LVHWNTKYGDFGKAVQQPD-GLAVLGIFLKVGSAKPGLQKVVDVL 163
           D K++A   H     ++H N +  D  K ++ P  G+  + +   +      +  VV V+
Sbjct: 645 DDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVI 704

Query: 164 DSIKTKGKSADFTNF 178
           DS K K KS D  NF
Sbjct: 705 DSGKVKEKSFDALNF 719


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,428,305
Number of Sequences: 37866
Number of extensions: 526771
Number of successful extensions: 1045
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 957
Number of HSP's gapped (non-prelim): 41
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press