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Search of human proteins with 4507651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 469 e-132
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 397 e-111
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 386 e-107
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 377 e-105
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 367 e-102
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 363 e-101
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 358 2e-99
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 344 5e-95
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 338 2e-93
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 334 4e-92
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 330 7e-91
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 330 9e-91
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 322 2e-88
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 321 4e-88
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 317 8e-87
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 298 4e-81
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 286 9e-78
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 76 2e-14
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 76 3e-14
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 74 9e-14
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 74 9e-14
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 74 9e-14
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 74 1e-13
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 74 1e-13
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 74 1e-13
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 74 1e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 2e-13
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 72 6e-13
gi|38044112 restin isoform b [Homo sapiens] 69 3e-12
gi|4506751 restin isoform a [Homo sapiens] 69 3e-12
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 469 bits (1206), Expect = e-132
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE
Sbjct: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE
Sbjct: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ
Sbjct: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Query: 241 TLNELNCI 248
TLNELNCI
Sbjct: 241 TLNELNCI 248
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 397 bits (1019), Expect = e-111
Identities = 209/242 (86%), Positives = 223/242 (92%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L +++K++ + + D+ + + Q +L+ ++ AEGDVAALNRRIQLVEEELDRA
Sbjct: 43 LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE
Sbjct: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 222
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN
Sbjct: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
Query: 247 CI 248
CI
Sbjct: 283 CI 284
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 386 bits (991), Expect = e-107
Identities = 199/246 (80%), Positives = 228/246 (92%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAG+ ++EAVKRKIQ LQQQAD+AE+RA+ LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
EADRKYEEVARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KEDKYEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLE+KL KEE++ + LDQ
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 241 TLNELN 246
TL +LN
Sbjct: 241 TLLDLN 246
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 377 bits (967), Expect = e-105
Identities = 196/245 (80%), Positives = 223/245 (91%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAG+ ++EAVKRKIQ LQQQAD+AE+RA+ LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
EADRKYEEVARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KEDKYEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 TLNEL 245
TL++L
Sbjct: 241 TLHDL 245
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 367 bits (943), Expect = e-102
Identities = 188/246 (76%), Positives = 223/246 (90%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAG+ ++EAVKRKIQ LQQQAD+AE+RA+ LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
EADRKYEEVARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KEDKYEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLE+KL KEE++ + LDQ
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 241 TLNELN 246
TL +LN
Sbjct: 241 TLLDLN 246
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 88 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 147
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
Query: 148 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 207
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
Query: 208 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 248
R + +E ++ EE+ A+ + + + L C+
Sbjct: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 363 bits (933), Expect = e-101
Identities = 194/244 (79%), Positives = 218/244 (89%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAG +SLEAV+RKI++LQ+QAD AE+RA LQRELD ER+ RE AE DVA+LNRRIQLVE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
+ADRKYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+
Sbjct: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KED+YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L Q E+N L L
Sbjct: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
Query: 241 TLNE 244
LNE
Sbjct: 241 ALNE 244
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 358 bits (919), Expect = 2e-99
Identities = 185/245 (75%), Positives = 218/245 (88%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
MAG+ ++EAVKRKIQ LQQQAD+AE+RA+ LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
EADRKYEEVARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
KEDKYEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 TLNEL 245
TL++L
Sbjct: 241 TLHDL 245
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 88 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 147
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
Query: 148 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 207
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
Query: 208 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 248
R + +E ++ EE+ A+ + + + L C+
Sbjct: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 344 bits (882), Expect = 5e-95
Identities = 178/242 (73%), Positives = 211/242 (87%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
KYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL E
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
Query: 245 LN 246
LN
Sbjct: 281 LN 282
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 338 bits (868), Expect = 2e-93
Identities = 178/240 (74%), Positives = 204/240 (85%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
+ A ++ ++ + + D + + L E KAE DVA+LNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
EEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 334 bits (857), Expect = 4e-92
Identities = 175/239 (73%), Positives = 205/239 (85%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
+A+++K++ + + ++ + + Q +L+ ++ AE DVA+LNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
EVARKLVILEGELER+EERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
EIKLL +KLKEAETRAEFAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 282
Score = 57.0 bits (136), Expect = 1e-08
Identities = 33/114 (28%), Positives = 63/114 (55%)
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+ + +K+ +L+ + E A +RAE +E E+ K + ++L+ + ++ +KY
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +K +KL++AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 330 bits (846), Expect = 7e-91
Identities = 170/244 (69%), Positives = 207/244 (84%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
+ L A+++K++ + + D+ + + Q +L+ ++ AE +VA+LNRRIQLVEEELD
Sbjct: 42 DELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD 101
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
RAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADR
Sbjct: 102 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 161
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
KYEEVARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDK
Sbjct: 162 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
YEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLE++L K + + + LD LN+
Sbjct: 222 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 281
Query: 245 LNCI 248
+ I
Sbjct: 282 MTSI 285
Score = 35.0 bits (79), Expect = 0.061
Identities = 21/99 (21%), Positives = 46/99 (46%)
Query: 148 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 207
E + K L+ + +N + + EA ++ E+ + E+E+ + KLK E +
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
Query: 208 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
+ ++ ++ E+K A A+ E L++ + EL+
Sbjct: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD 101
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 330 bits (845), Expect = 9e-91
Identities = 170/241 (70%), Positives = 205/241 (85%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
+A+++K++ + + ++ + + Q +L+ ++ AE DVA+LNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
EVARKLVILEGELER+EERAEV+E KCGDLEEELK VTNNLKSLEA ++KYS KEDKYEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEE 223
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNC 247
EIKLL +KLKEAETRAEFAER+VAKLEKTIDDLE+++ K + + + LD LN++
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITS 283
Query: 248 I 248
+
Sbjct: 284 L 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 322 bits (825), Expect = 2e-88
Identities = 168/242 (69%), Positives = 205/242 (84%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
KYEEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL E
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
Query: 245 LN 246
LN
Sbjct: 281 LN 282
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/114 (31%), Positives = 63/114 (55%)
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+ + +K+ +L+ + E A +RAE +E E+ K + + L SL+ + ++ DKY
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +K +KL+ AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 321 bits (822), Expect = 4e-88
Identities = 167/244 (68%), Positives = 204/244 (83%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
KYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L K + + + LD LN+
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
Query: 245 LNCI 248
+ I
Sbjct: 281 MTSI 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 317 bits (811), Expect = 8e-87
Identities = 168/240 (70%), Positives = 198/240 (82%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
+ A ++ ++ + + D + + L E KAE DVA+LNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
EEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 298 bits (762), Expect = 4e-81
Identities = 156/241 (64%), Positives = 197/241 (81%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
KYEEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L K + + + LD LN+
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
Query: 245 L 245
+
Sbjct: 281 M 281
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/114 (31%), Positives = 63/114 (55%)
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+ + +K+ +L+ + E A +RAE +E E+ K + + L SL+ + ++ DKY
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +K +KL+ AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
Score = 56.2 bits (134), Expect = 3e-08
Identities = 35/164 (21%), Positives = 86/164 (52%), Gaps = 6/164 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+R ++ ++ +A + E++ + + +L + E A+ + R++ ++E +L+RA+ER
Sbjct: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
Query: 71 ATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
+ +++LEE + D++ + + E++ + E++ E ++K +EA+ + E
Sbjct: 184 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETRAE 240
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSL 171
R + LE ++ E+ +LK + EEL + N++ S+
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 286 bits (733), Expect = 9e-78
Identities = 154/240 (64%), Positives = 189/240 (78%), Gaps = 11/240 (4%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
++A+K+K+Q L+ + A DRA+ + + +R ++ E + AL ++++ E+E++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
K E+EKAADESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKY
Sbjct: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
EEVARKLVILEGELER+EERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYE
Sbjct: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
EEIKLL +KLKEAETRAEFAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 76.3 bits (186), Expect = 2e-14
Identities = 70/250 (28%), Positives = 118/250 (47%), Gaps = 36/250 (14%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ +++ALQ++ +A+ ++ Q E +E+ +A D A L ++ + E +R +E L
Sbjct: 867 EEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEAL 926
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 130
A A+Q+L++A++AA G++ A +EK +QE +LK AK A
Sbjct: 927 ACAVQELQDAKEAASREREGLE--RQVAGLQQEKESLQE-KLKAAK-----------AAA 972
Query: 131 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLK-SLEAASEKYSEKEDKYEEEI 189
L L+ +L +AE+RA+ L+E N LK L A Y + EE
Sbjct: 973 GSLPGLQAQLAQAEQRAQ-------SLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEEC 1025
Query: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLA--------------QAKEENVGLH 235
K L +L+E + + AE V KL+ T D+ EKL+ + +E L
Sbjct: 1026 KSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALR 1085
Query: 236 QTLDQTLNEL 245
+ L++T EL
Sbjct: 1086 EDLERTQKEL 1095
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/252 (20%), Positives = 113/252 (44%), Gaps = 33/252 (13%)
Query: 5 NSLEAVKRKIQALQQQADEAED-----------RAQGLQRELDGERERREKAEGDVAALN 53
N+++ ++ +Q L+ A E E+ Q L +EL+ R+ +K +A+
Sbjct: 310 NTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLASFP 369
Query: 54 RRIQLVEEELDRAQERL-------ATALQKLEEAEKAADESERGMKVIE--NRAMKDEEK 104
+ + +++ D A + + A Q+++E + ER +E NR + +
Sbjct: 370 GWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLE 429
Query: 105 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 164
++E+QLKE +A E + +++ L+ EL + A+ + +L +
Sbjct: 430 QLVKELQLKE------DARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSW 483
Query: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224
L L ++ E+++ E+E++ L+ +L +F E +A++ + + DLEE+
Sbjct: 484 EEELAELRREKKQQQEEKELLEQEVRSLTRQL-------QFLETQLAQVSQHVSDLEEQK 536
Query: 225 AQAKEENVGLHQ 236
Q ++ L Q
Sbjct: 537 KQLIQDKDHLSQ 548
Score = 51.6 bits (122), Expect = 6e-07
Identities = 52/265 (19%), Positives = 122/265 (46%), Gaps = 26/265 (9%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNR-----RIQLVEE 61
L+A++ QALQQ+ + L+ E R ++ E + A+ + + Q+ E+
Sbjct: 639 LQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEK 698
Query: 62 E--LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIA 119
E L + +++E+ ++ A+ R ++ +E++ + + +E+ + K + +
Sbjct: 699 EAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAE-KGQQGVG 757
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNN---LKSLEAASE 176
D + E+A +L + + +LE + + + + DL+ +++ ++ ++S + +E
Sbjct: 758 PPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAE 817
Query: 177 KYSEKEDKYEEEIKLLSDKLKEAETR--AEFAERTVAKLEKTIDD----------LEEKL 224
+ +++K ++ L A + + +ER A E+ D+ L+E+L
Sbjct: 818 AVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEEL 877
Query: 225 AQAK---EENVGLHQTLDQTLNELN 246
+QAK EE H L + L+ N
Sbjct: 878 SQAKCSSEEAQLEHAELQEQLHRAN 902
Score = 51.2 bits (121), Expect = 8e-07
Identities = 53/244 (21%), Positives = 101/244 (41%), Gaps = 21/244 (8%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATAL 74
QA Q E + QGL+ G E+ E + L +Q + +EL+ ++ L
Sbjct: 306 QATQNTVKELQTCLQGLEL---GAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKN 362
Query: 75 QKL-----------EEAEKAADESERGMKVIENRAMKDEE---KMEIQEMQLKEAKHIAE 120
Q L ++A+ A+D R + + A + +E K++ E + + + +
Sbjct: 363 QHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNR 422
Query: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
+ + E++ ++L + E RA V E+ L+EEL L ++
Sbjct: 423 QQSAQLEQLVKELQLKEDA--RASLERLVKEM--APLQEELSGKGQEADQLWRRLQELLA 478
Query: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
+EEE+ L + K+ + E E+ V L + + LE +LAQ + L + Q
Sbjct: 479 HTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQ 538
Query: 241 TLNE 244
+ +
Sbjct: 539 LIQD 542
Score = 48.9 bits (115), Expect = 4e-06
Identities = 55/244 (22%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
LE + ++Q LQ Q + + + + + D + + AE + +Q ++E+ +
Sbjct: 778 LEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEAL 837
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
L + E E A E + A + EE++ + +L +AK +EEA ++
Sbjct: 838 NRAHVQELLQCSEREGALQEERA------DEAQQREEELRALQEELSQAKCSSEEAQLEH 891
Query: 127 EEVARKLVILEGELERAE-ERAEVSELKCGDLEEELKNVTNNL----KSLEAASEKYSEK 181
E L+ +L RA + AE+ C L E + V L + L+ A E S +
Sbjct: 892 AE-------LQEQLHRANTDTAELGIQVCA-LTVEKERVEEALACAVQELQDAKEAASRE 943
Query: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
+ E ++ L + + + + + A+ L L+ +LAQA++ L + Q
Sbjct: 944 REGLERQVAGLQQEKESLQEKLKAAKAAAGSL----PGLQAQLAQAEQRAQSLQEAAHQE 999
Query: 242 LNEL 245
LN L
Sbjct: 1000 LNTL 1003
Score = 42.7 bits (99), Expect = 3e-04
Identities = 52/247 (21%), Positives = 105/247 (42%), Gaps = 22/247 (8%)
Query: 19 QQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEE---ELDRAQERLATALQ 75
Q+ E ++ Q L+RE E + + L + +QL E+ L+R + +A +
Sbjct: 398 QEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQE 457
Query: 76 KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI 135
+L + AD+ R ++ + EE++ + K+ + E +++ + R+L
Sbjct: 458 ELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQF 517
Query: 136 LEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK---EDKYEEEIKLL 192
LE +L + + E + L ++ +++ + LE + + + E + +
Sbjct: 518 LETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPV 577
Query: 193 SDKLKEAETRAEFAERTVAKLEKTIDDL-------EEKLAQAKEE-------NVGLHQTL 238
+ L+EA + E +R + E +DD EE+L QA E VG +Q L
Sbjct: 578 NSSLQEAWGKPEEEQRGLQ--EAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLL 635
Query: 239 DQTLNEL 245
+ L L
Sbjct: 636 EGKLQAL 642
Score = 40.8 bits (94), Expect = 0.001
Identities = 53/223 (23%), Positives = 89/223 (39%), Gaps = 17/223 (7%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
L + +A + LQ Q +AE RAQ LQ E + L+ I + L
Sbjct: 965 LKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLK------FQLSAEIMDYQSRL 1018
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
A E + +LEE + +E ++ ++ EK+ L E + D
Sbjct: 1019 KNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKD 1078
Query: 124 RKYEEVARKLVILEGELERAEER-AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
++ + L + ELE+A + E C ++ +N L L+ + +
Sbjct: 1079 KEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLN-----RT 1133
Query: 183 DKYEEE--IKLLSDK--LKEAETRAEFAERTVAKLEKTIDDLE 221
KY EE I+LL DK L + EF ++ A+ E+ + D E
Sbjct: 1134 KKYLEERLIELLRDKDALWQKSDALEFQQKLSAE-ERWLGDTE 1175
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 75.9 bits (185), Expect = 3e-14
Identities = 57/218 (26%), Positives = 108/218 (49%), Gaps = 11/218 (5%)
Query: 18 QQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKL 77
Q++ E E++ Q + E E+E+R++ E + +I+ EE++ +E++ +K+
Sbjct: 450 QEKIREQEEKRQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQE--MQLKEAKHIAEEADRKYEE----VAR 131
E EK +E +R + + EEK+ QE + KE H EE RK EE
Sbjct: 508 HEQEKIREEEKRQE---QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 132 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 191
K+ E ++ EE+ E K + EE+++ ++ E +++ EK + EE++
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 192 LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
+K++E E + E + + EK I + EEK+ + +E
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 71.2 bits (173), Expect = 8e-13
Identities = 47/222 (21%), Positives = 109/222 (49%), Gaps = 1/222 (0%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E + R+ + + +Q E+ + Q E+ + E+ + E ++ +I EE++ + +
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQE 556
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E++ +K+ + E+ E E + E + + EEK+ QE +++E + + +E + K
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
E K+ E +++ EE+ E K + E++++ ++ E ++ EK + EE
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
++ +K++E E + E + + E + EEK+ + +E
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 70.9 bits (172), Expect = 1e-12
Identities = 50/225 (22%), Positives = 107/225 (47%), Gaps = 6/225 (2%)
Query: 12 RKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLA 71
R+ + Q+Q + + + ++ + + RE+ EK ++ + ++ EEE + QE +
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
Query: 72 TALQKLEEAEKA------ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
+K+ E E+ E E ++ E + + EEKM QE +++E + + K
Sbjct: 527 RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK 586
Query: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
E K+ E ++ EE + E K G+ EE++ ++ E + EK +
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
E++I+ +K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 64.3 bits (155), Expect = 9e-11
Identities = 51/220 (23%), Positives = 101/220 (45%), Gaps = 14/220 (6%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ K++ ++ E E++ + L+ ++ + + RE+ E + EEE R QE+
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----------KRQEEEKIREQEKR 472
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 130
K+ E+ E E ++ E + + EEK+ QE +E K +E + EE
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 532
Query: 131 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIK 190
R+ + E+ R +E+ E K EE++ + E + EK + EE+I+
Sbjct: 533 RE----QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 191 LLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+K++E E + E + E+ + + EEK+ + +E+
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Score = 60.5 bits (145), Expect = 1e-09
Identities = 43/199 (21%), Positives = 94/199 (47%), Gaps = 13/199 (6%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ +I +++ E E++ + + ++ + E+ E + ++ EE++ +E++
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 130
+K+ E E+ E E M E + + EEKM+ QE +++ + E ++K E
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 131 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK-YEEEI 189
K+ E ++ EE+ E K + EE+ ++ EK +E+K +E+E+
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEK----------MQEQEEKMRRQEEKMWEQEV 704
Query: 190 KL--LSDKLKEAETRAEFA 206
+L +K++E + E A
Sbjct: 705 RLRQQEEKMQEHQEHLEAA 723
Score = 58.2 bits (139), Expect = 7e-09
Identities = 53/237 (22%), Positives = 105/237 (44%), Gaps = 21/237 (8%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERRE-------KAEGDVAALNRRIQLVEEELDRAQ 67
Q LQ +AD Q + +L + E E + E + +IQ EE++ +
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 381
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E++ +K+ E E+ E M E + + EE M +E +++ + + E + K
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELK-NVTNNLKSLEAASEKYSEKEDKY- 185
E+ K+ E E+ E+R E +++ + +E + + + + EK E+E+K
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 186 -EEEIKLLSDKLKEAETRAEFAE-----------RTVAKLEKTIDDLEEKLAQAKEE 230
+EE +K++E E R E E + + ++ I + EEK+ + +E+
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Score = 57.4 bits (137), Expect = 1e-08
Identities = 56/229 (24%), Positives = 110/229 (48%), Gaps = 17/229 (7%)
Query: 10 VKRKIQALQQQADEAEDRAQGLQRELDGER----ERREKAEGDVAALNRRIQLVEEELDR 65
++ K+Q ++ + E + + L+R+L+ + +++ +AE D L + +Q V +L
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD--HLGKELQSVSAKLQA 344
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
E + ++ E+ E ++ E + + EEK+ QE +++E EE R+
Sbjct: 345 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE----QEEKMRR 400
Query: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEA---ASEKYSEKE 182
EE+ + E ++ R EE E K EE + ++ LE EK E+E
Sbjct: 401 QEEMMWE---KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 183 DKYEEEIKLL-SDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+K +EE K+ +K +E E + E + + E+ I + EEK+ + +E+
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Score = 52.8 bits (125), Expect = 3e-07
Identities = 61/260 (23%), Positives = 105/260 (40%), Gaps = 36/260 (13%)
Query: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
+L AV + + + +E L EL E+ + A L ++QLVE E
Sbjct: 241 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 300
Query: 66 AQERLATALQKLEEA---------EKAADESERGMKVIENRA--------------MKDE 102
Q + +KLE A + AD + ++ + + + E
Sbjct: 301 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 360
Query: 103 EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK 162
EKM QE +++E + +E + K E K+ E ++ R EE E K EE +
Sbjct: 361 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420
Query: 163 NVTNNLKSLE----AASEKYSEKEDKYEEEIKLL--------SDKLKEAETRAEFAERTV 210
++ E EK E E+K E+ K+ +K++E E R E E +
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE-QEAKM 479
Query: 211 AKLEKTIDDLEEKLAQAKEE 230
+ E+ I + EEK+ + +E+
Sbjct: 480 WRQEEKIREQEEKIREQEEK 499
Score = 35.4 bits (80), Expect = 0.046
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 23/161 (14%)
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 137
E+ +KA+ + + ++ + + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 225
Query: 138 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 187
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 226 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 278
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 279 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 316
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 74.3 bits (181), Expect = 9e-14
Identities = 50/215 (23%), Positives = 109/215 (50%), Gaps = 1/215 (0%)
Query: 12 RKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLA 71
R+ + +++Q ++ ++ + + R+ + RE+ EK + + R+ + + E+ ++ QE++
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 72 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR 131
+K+ E ++ E E M E + + EE M+ QE +L+E + +E + K +E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 132 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 191
K+ E +++ EE+ E K EE++ + E + EK + EE+++
Sbjct: 470 KIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 192 LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 226
+K++E E R E + + E + +LEE+L +
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 67.0 bits (162), Expect = 1e-11
Identities = 54/242 (22%), Positives = 123/242 (50%), Gaps = 19/242 (7%)
Query: 7 LEAVKRKIQA----------LQQQADEA----EDRAQGLQRELDGERERREKAEGDVAAL 52
L++V K+QA L QQ +E E++ Q + ++ + + + E +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 53 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
++ EE++ ++++ +K+ E E+ E E M E + + +EK++ QE ++
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 113 -KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV---SELKCGDLEEELKNVTNNL 168
++ + I E+ +++ E++ R+ + + E+ E+ E E K +LEE +++ L
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 169 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ +E ++ EK + EE+I+ +K++E E + + + + K E+ I + EEK+ + +
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 229 EE 230
E+
Sbjct: 510 EK 511
Score = 67.0 bits (162), Expect = 1e-11
Identities = 46/210 (21%), Positives = 112/210 (53%), Gaps = 16/210 (7%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E + R+ + +++Q ++ +++ + + R+ + RE+ EK + + ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEADRKY 126
E + +K+ E E+ + E ++ +E + ++EEKM+ QE ++ ++ + I E+ ++ +
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY- 185
+ KL+ E ++ EE+ E K + EE+ ++ EK +E+K
Sbjct: 487 RQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEK----------MQEQEEKMQRQEEKMR 534
Query: 186 EEEIKL--LSDKLKEAETRAEFAERTVAKL 213
E+E++L +K++E E R + E + KL
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Score = 66.2 bits (160), Expect = 2e-11
Identities = 54/237 (22%), Positives = 106/237 (44%), Gaps = 11/237 (4%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERRE-------KAEGDVAALNRRIQLVEEELDRAQ 67
Q LQ +AD Q + +L + E E + E + +IQ EE++ +
Sbjct: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
++ +K+ E+ E E ++ E++ + EEK+ QE +++E + + K
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDL----EEELKNVTNNLKSLEAASEKYSEKED 183
E K+ E E+ R EE+ E K + E++++ ++ E + EK
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 184 KYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
+ EE ++ +KL+E E + + E + + E+ I EEK+ + +E+ + L Q
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 61.2 bits (147), Expect = 8e-10
Identities = 48/214 (22%), Positives = 103/214 (48%), Gaps = 9/214 (4%)
Query: 23 EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 82
E E++ + ++ + E+ + E + +I+ EE++ +E++ +K+ E ++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 83 AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELER 142
E E M E + + EEK QE ++ K + E+ D K E ++ E ++
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRE 438
Query: 143 AEERAEVSELKCGDLEEELKNVTNNL----KSLEAASEKYSEKEDKYEEEIKLL--SDKL 196
EE + E K ++EE+++ + + ++ EK E+E+K + KLL +K+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 197 KEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
E E + E + + E+ + + EEK+ + +E+
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Score = 60.8 bits (146), Expect = 1e-09
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 24/245 (9%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E +K K LQ++ E +Q + + + E+A+ + +++Q+ + L +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ--LLLPQQQLQVEADRLGKEL 271
Query: 68 ERLATALQ-KLEEAEK---AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
+ ++ LQ ++EE E + E M E + + EEKM QE++++E + +
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL-----------KNVTNNLKSLE 172
K E K+ E ++ R EE+ E K + EE++ + + + +
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391
Query: 173 AASEKYSEKEDK-------YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLA 225
EK E+E+K E++++ +K++E E E + +LE+ + D EEKL
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 226 QAKEE 230
+ +E+
Sbjct: 452 EVEEK 456
Score = 55.8 bits (133), Expect = 3e-08
Identities = 48/225 (21%), Positives = 107/225 (47%), Gaps = 5/225 (2%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKA---EGDVAALNRRIQLVEEELD 64
E + R+ + +++Q ++ ++ + + R+ + RE E E + + ++Q EE++
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
+E++ +K++E E+ E+ +K E + + EEKM QE ++ E + +E +
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
K + K+ E L + EE+ + E++ +LEE L + + L A + +
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
I + K +EA++ + + L++ + ++ LA KE
Sbjct: 585 TLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQ-LASGKE 628
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/121 (25%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L V+ K+Q +++ E E++ Q + ++ + E+ + E + +I EE++ R
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQ 508
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
+E++ +K++E E+ E M+ E R + EEKM+ QE++L+E + + +K
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 127 E 127
E
Sbjct: 569 E 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 74.3 bits (181), Expect = 9e-14
Identities = 50/215 (23%), Positives = 109/215 (50%), Gaps = 1/215 (0%)
Query: 12 RKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLA 71
R+ + +++Q ++ ++ + + R+ + RE+ EK + + R+ + + E+ ++ QE++
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 72 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR 131
+K+ E ++ E E M E + + EE M+ QE +L+E + +E + K +E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 132 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 191
K+ E +++ EE+ E K EE++ + E + EK + EE+++
Sbjct: 470 KIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 192 LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 226
+K++E E R E + + E + +LEE+L +
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 67.0 bits (162), Expect = 1e-11
Identities = 54/242 (22%), Positives = 123/242 (50%), Gaps = 19/242 (7%)
Query: 7 LEAVKRKIQA----------LQQQADEA----EDRAQGLQRELDGERERREKAEGDVAAL 52
L++V K+QA L QQ +E E++ Q + ++ + + + E +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 53 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
++ EE++ ++++ +K+ E E+ E E M E + + +EK++ QE ++
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 113 -KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV---SELKCGDLEEELKNVTNNL 168
++ + I E+ +++ E++ R+ + + E+ E+ E E K +LEE +++ L
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 169 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ +E ++ EK + EE+I+ +K++E E + + + + K E+ I + EEK+ + +
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 229 EE 230
E+
Sbjct: 510 EK 511
Score = 67.0 bits (162), Expect = 1e-11
Identities = 46/210 (21%), Positives = 112/210 (53%), Gaps = 16/210 (7%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E + R+ + +++Q ++ +++ + + R+ + RE+ EK + + ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEADRKY 126
E + +K+ E E+ + E ++ +E + ++EEKM+ QE ++ ++ + I E+ ++ +
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY- 185
+ KL+ E ++ EE+ E K + EE+ ++ EK +E+K
Sbjct: 487 RQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEK----------MQEQEEKMQRQEEKMR 534
Query: 186 EEEIKL--LSDKLKEAETRAEFAERTVAKL 213
E+E++L +K++E E R + E + KL
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Score = 66.2 bits (160), Expect = 2e-11
Identities = 54/237 (22%), Positives = 106/237 (44%), Gaps = 11/237 (4%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERRE-------KAEGDVAALNRRIQLVEEELDRAQ 67
Q LQ +AD Q + +L + E E + E + +IQ EE++ +
Sbjct: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
++ +K+ E+ E E ++ E++ + EEK+ QE +++E + + K
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDL----EEELKNVTNNLKSLEAASEKYSEKED 183
E K+ E E+ R EE+ E K + E++++ ++ E + EK
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 184 KYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
+ EE ++ +KL+E E + + E + + E+ I EEK+ + +E+ + L Q
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 61.2 bits (147), Expect = 8e-10
Identities = 48/214 (22%), Positives = 103/214 (48%), Gaps = 9/214 (4%)
Query: 23 EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 82
E E++ + ++ + E+ + E + +I+ EE++ +E++ +K+ E ++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 83 AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELER 142
E E M E + + EEK QE ++ K + E+ D K E ++ E ++
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRE 438
Query: 143 AEERAEVSELKCGDLEEELKNVTNNL----KSLEAASEKYSEKEDKYEEEIKLL--SDKL 196
EE + E K ++EE+++ + + ++ EK E+E+K + KLL +K+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 197 KEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
E E + E + + E+ + + EEK+ + +E+
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Score = 60.8 bits (146), Expect = 1e-09
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 24/245 (9%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E +K K LQ++ E +Q + + + E+A+ + +++Q+ + L +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ--LLLPQQQLQVEADRLGKEL 271
Query: 68 ERLATALQ-KLEEAEK---AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
+ ++ LQ ++EE E + E M E + + EEKM QE++++E + +
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL-----------KNVTNNLKSLE 172
K E K+ E ++ R EE+ E K + EE++ + + + +
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391
Query: 173 AASEKYSEKEDK-------YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLA 225
EK E+E+K E++++ +K++E E E + +LE+ + D EEKL
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 226 QAKEE 230
+ +E+
Sbjct: 452 EVEEK 456
Score = 55.8 bits (133), Expect = 3e-08
Identities = 48/225 (21%), Positives = 107/225 (47%), Gaps = 5/225 (2%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKA---EGDVAALNRRIQLVEEELD 64
E + R+ + +++Q ++ ++ + + R+ + RE E E + + ++Q EE++
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
+E++ +K++E E+ E+ +K E + + EEKM QE ++ E + +E +
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
K + K+ E L + EE+ + E++ +LEE L + + L A + +
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
Query: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
I + K +EA++ + + L++ + ++ LA KE
Sbjct: 585 TLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQ-LASGKE 628
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/121 (25%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L V+ K+Q +++ E E++ Q + ++ + E+ + E + +I EE++ R
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQ 508
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
+E++ +K++E E+ E M+ E R + EEKM+ QE++L+E + + +K
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 127 E 127
E
Sbjct: 569 E 569
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 74.3 bits (181), Expect = 9e-14
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 11/219 (5%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATAL 74
Q LQ +AD Q + +L + E E NR Q EE++ R +E++
Sbjct: 249 QQLQAEADHLGKELQSVSAKLQAQVEENE-------LWNRLNQQQEEKMWRQEEKIQERE 301
Query: 75 QKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR--- 131
+K++E E+ E E M+ E + EEKM QE + E + E + K E +
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 132 -KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIK 190
+ E E R +E+ + E K EE+++ ++ E ++ EK + EE++
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 191 LLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
++++E E + E + + EK I + EEK+ + +E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Score = 73.9 bits (180), Expect = 1e-13
Identities = 46/224 (20%), Positives = 110/224 (49%), Gaps = 1/224 (0%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERRE-KAEGDVAALNRRIQLVEEE 62
+ LE + + +++Q ++ ++ + ++E E+E + + E + +I+ EE
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
+ +E++ +K+ E E+ E E M+ E + + E+K+ QE +++E + + +E
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ K E K+ E +++ EE+ E K + E++++ ++ E ++ EK
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 226
+ EE++ +K++E E + E + + E + EEK+ +
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 73.6 bits (179), Expect = 2e-13
Identities = 49/213 (23%), Positives = 104/213 (48%), Gaps = 2/213 (0%)
Query: 18 QQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKL 77
Q++ E E++ Q + E E+E+R++ E + +I+ EE++ +E + +K+
Sbjct: 356 QEKIREQEEKRQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 137
E E+ E E M+ E + + EEK+ QE +++E + E + +E K+ E
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 138 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 197
G++ E + + E K EE+++ ++ E + E + EE++ +K+
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 198 EAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
E E + + E + + E+ + + E +L Q +E+
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 67.8 bits (164), Expect = 8e-12
Identities = 50/220 (22%), Positives = 101/220 (45%), Gaps = 10/220 (4%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ K++ ++ E E++ + L+ ++ + + RE+ E + EEE R QE+
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----------KRQEEEKIREQEKR 378
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 130
K+ E+ E E ++ E + EEKM QE ++ E + +E + K
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 131 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIK 190
K+ E ++ EE+ E + EE++ + EA ++ EK + EE+I+
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 191 LLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Score = 67.0 bits (162), Expect = 1e-11
Identities = 57/237 (24%), Positives = 117/237 (49%), Gaps = 15/237 (6%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRE-LDGERERREKAEGDVAALNRRIQLVEEELDR 65
L++V K+QA Q + +E +R Q E + + E+ ++ E + +I+ EE++ R
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
+E + +K+ E+ E E ++ +E + M ++EK+ QE + +E + I E+ R+
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQ 379
Query: 126 YEEVA-----RKLVILEGELERAEERAEVSELKCGDLEEEL----KNVTNNLKSLEAASE 176
+E K+ E ++ EE + E K G+ EE++ + + + + E
Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 177 KYSEKEDKY---EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
K E+E K EE+I+ + ++E E + E + + E + + EEK+ + +E+
Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/223 (19%), Positives = 106/223 (47%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E ++ + + +++Q + ++ + ++R+ + E+ EK ++ + ++ E+E R +
Sbjct: 309 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 368
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E +K +E E E ++ E + + EE M+ QE ++ E + E + + +
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
E K+ E ++ E++ E K + EE ++ + E + K + EE
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+++ +K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 58.2 bits (139), Expect = 7e-09
Identities = 37/174 (21%), Positives = 83/174 (47%), Gaps = 3/174 (1%)
Query: 8 EAVKRKIQALQQQAD---EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
E ++ + + +Q+Q + E E++ + E+ + E+ + E + ++I+ EE++
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
+E + +K+ E E E E M+ E + + EEK+ QE +++E + E +
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKY 178
+E K+ E ++ EE+ + E K EE+++ L+ E +++
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 57.4 bits (137), Expect = 1e-08
Identities = 59/248 (23%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
+L AV + + + +E L EL E+ + A L ++QLVE E
Sbjct: 168 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 227
Query: 66 AQERLATALQKLEEA---------EKAADESERGMKVIENRAMKDEEKMEI-------QE 109
Q + +KLE A + AD + ++ + + E+ E+ QE
Sbjct: 228 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 287
Query: 110 MQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLK 169
++ + +E + K +E K+ E ++ R EE E K EE + ++
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 170 SLEA---ASEKYSEKEDKYEEEIKLL-SDKLKEAETRAEFAERTVAKLEKTIDDLEEKLA 225
LE EK E+E+K +EE K+ +K +E E + E + + E+ I + +E++
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEEMM 406
Query: 226 QAKEENVG 233
Q +EE +G
Sbjct: 407 QEQEEKMG 414
Score = 56.2 bits (134), Expect = 3e-08
Identities = 55/231 (23%), Positives = 106/231 (45%), Gaps = 17/231 (7%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E +K K LQ++ E +Q + + + E+A+ L Q ++ E D
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK-----LLLPQQQLQAEADHLG 259
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
+ L + KL+ + + R + E + + EEK++ +E +++E EE R+ E
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ----EEKIREQE 315
Query: 128 EVARKLVIL----EGELERAEERAEVSELKCGDLEEEL--KNVTNNLKSLEAASEKYSEK 181
E R+ + E ++ R EE E K +LEE++ + + EK E+
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 182 EDKYEEEIKL--LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
E + E+E K+ +K++E E + E + + E+ + + EEK+ + +EE
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/175 (20%), Positives = 80/175 (45%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ KI+ ++ E E++ + ++ + E ++ E + +I+ E+++ +E++
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 130
+ ++E E+ E E M E + + EEKM QE +++E + E + K E
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 515
Query: 131 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
+ E ++ EE+ E K + EE+++ ++ E + EK ++
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 36.2 bits (82), Expect = 0.027
Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 137
E+ +KA+ + + ++ ++ + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 152
Query: 138 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 187
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 153 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 205
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 206 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 243
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 73.9 bits (180), Expect = 1e-13
Identities = 64/257 (24%), Positives = 112/257 (43%), Gaps = 23/257 (8%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA- 66
+ + +K AL++ E E LQ +LD ER R KAE L ++ ++ EL+
Sbjct: 1101 DEIAQKNNALKK-IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 67 ------QERLATALQKLEEAEKAADESERGMKV-IENRAMKDEEKMEIQEMQLKEAKHIA 119
QE A Q++ +KA DE R + ++ K + +E QL++ K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 179
D+ + + ++ L GEL + + E K LE +++ + + E A + +
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1279
Query: 180 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEE--------------KLA 225
+K K + E++ ++ L EAE +A + VA L + D +E KL
Sbjct: 1280 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1339
Query: 226 QAKEENVGLHQTLDQTL 242
Q +EE L LD+ +
Sbjct: 1340 QLEEERNSLQDQLDEEM 1356
Score = 68.9 bits (167), Expect = 4e-12
Identities = 65/255 (25%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 20 QADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 79
Q E+ Q + EL +ER++KAE ++ L ++ + EE + QE+L + E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 80 AEK-----AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE----EADRKYEEVA 130
AE+ AA + E + E A +EE+ Q++Q + K + E + EE A
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 131 RKLVILEGELERAEERAEVSELKCGD------------LEEELKNVTNNLKSLEAASEKY 178
R+ + LE A+ + E+ D LEE + ++T NL E ++
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 179 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE-------KTIDDLEEKLAQAKEEN 231
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++A+ K +
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 232 VGLHQTLDQTLNELN 246
+ L L L+
Sbjct: 1086 AKKEEELQAALARLD 1100
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/243 (22%), Positives = 113/243 (46%), Gaps = 9/243 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQE-- 68
+ ++QA + + + ++R Q + EL ++ + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 69 -RLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
RLA Q+LEE + +E +RG ++ R ++ ++++E QL+E + ++
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 969
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ K+ LE E+ +++ + LEE + ++T NL E ++ ++ +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
+K+E I L +LK+ E + E+ KLE D E++A + + L L +
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 243 NEL 245
EL
Sbjct: 1090 EEL 1092
Score = 65.1 bits (157), Expect = 5e-11
Identities = 56/240 (23%), Positives = 111/240 (46%), Gaps = 14/240 (5%)
Query: 2 AGLNSLEAVKRKIQALQQQAD-EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
A L L+ + ++QAD E E+ A+ L L G R + + L RI +E
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG----RNALQDEKRRLEARIAQLE 1742
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE---EKMEIQEMQLKEAKH 117
EEL+ Q + ++ +A + A++ + + A K+E +++E Q +L+ H
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 118 IAEEADR-KYEE----VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E A + K++ + K+ LE ++E+ + + +++LK + ++
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD-LEEKLAQAKEEN 231
+E+Y E+ +K +K L +L+EAE ++ KL++ +D+ E A +E N
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1922
Score = 62.4 bits (150), Expect = 4e-10
Identities = 73/283 (25%), Positives = 135/283 (47%), Gaps = 52/283 (18%)
Query: 6 SLEAVKRKIQA-LQQQADEAEDRAQGLQR-------ELDGERERR-------EKAEGDV- 49
+++A+K + + LQ + ++ E++ + LQR EL+ ER++R +K EGD+
Sbjct: 1568 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
Query: 50 -------AALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 102
+A+ R + +++ L + Q ++ ++LE+A + DE K E +A E
Sbjct: 1628 DLELQADSAIKGREEAIKQ-LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 103 -EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI-LEGELERAEERAEVSELKCGDLEEE 160
+ M++QE L A+ ++AD + EE+A +L L G +E+ + E + LEEE
Sbjct: 1687 ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEEE 1744
Query: 161 L---------------------KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 199
L + ++N L + + ++K + E + K L KL E
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 200 E--TRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +++F + T+A LE I LEE++ Q E ++L Q
Sbjct: 1805 EGAVKSKF-KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/214 (24%), Positives = 107/214 (50%), Gaps = 22/214 (10%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQG-LQRELDGERERREKAE---GDVAALNRRI 56
++G N+L+ KR+++A Q +E + QG ++ D R+ ++AE ++A
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 57 QLVE---EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 113
Q E ++L+R + L + L ++E A K+ +S + +E + + EE++E + + +
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1838
Query: 114 EAKHIAEEADRKYEEVARKLVILEGELERAEE--------RAEVSELK--CGDLEEELKN 163
A ++ D+K +E+ L+ +E E + AE+ A V +LK + EEE +
Sbjct: 1839 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 197
+ N + L+ ++ +E + E+ L KL+
Sbjct: 1896 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 54.7 bits (130), Expect = 7e-08
Identities = 52/238 (21%), Positives = 109/238 (45%), Gaps = 26/238 (10%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E ++ QA+++ ++ E + + LD ++ EK D+A R + ++E++ +
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRA-KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Query: 68 ERLATALQKLE----EAEKAADE-------------SERGM-KVIENRAMKDEEKMEIQE 109
++L +Q+L+ + E+A E S GM E +A+K + +
Sbjct: 1255 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 110 MQLKEAKHIAEEADRKYEEVARKLVILEGE-------LERAEERAEVSELKCGDLEEELK 162
QL++ + + +E R+ V+ KL LE E L+ E + E L +L
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 163 NVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ L+ + E E + ++++EI+ L+ + +E + E+T +L++ +DDL
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Score = 52.4 bits (124), Expect = 4e-07
Identities = 48/235 (20%), Positives = 104/235 (44%), Gaps = 14/235 (5%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L ++ + +LQ Q DE + Q L+R + + ++ + ++ +EE R
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Q+ + Q+ EE A D+ E+ +NR ++ + + + ++ E+ RK+
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+++ + + + +RAE E+E K + SL A E+ E +++ E
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAR-----EKETKAL-----SLARALEEALEAKEELE 1503
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
K+L ++++ + + + V +LEK+ LE ++ + K + L L T
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Score = 52.0 bits (123), Expect = 5e-07
Identities = 57/263 (21%), Positives = 119/263 (45%), Gaps = 37/263 (14%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE---L 63
LE + + Q LQ + + + L+ +L+ E R+K + + +I+ +E+E +
Sbjct: 931 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM 990
Query: 64 DRAQERLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
D +L+ + LEE A+E E+ + + +K++ + I E++++ K
Sbjct: 991 DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKE- 1046
Query: 119 AEEADRKYEEVARKLVILEGEL-----ERAEERAEVSELK-------------CGDLEEE 160
E++ ++ E++ RK LEG+ + A+ +A+++ELK L++E
Sbjct: 1047 -EKSRQELEKLKRK---LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 161 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ N LK + S+ ++ + E + K+ E E +LE T+D
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 221 ---EEKLAQAKEENVGLHQTLDQ 240
+E A+ ++E L + LD+
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDE 1185
Score = 50.4 bits (119), Expect = 1e-06
Identities = 59/264 (22%), Positives = 114/264 (43%), Gaps = 32/264 (12%)
Query: 10 VKRKIQALQQQADEAE-------DRAQGLQRELDGERERREKAEG-------DVAALNRR 55
++ ++Q LQ + + E D+ LQ E++ +AEG DVA+L+ +
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 56 IQLVEEELD---RAQERLATALQKLEEAEKAA-DESERGMKVIENRAMKDEEKMEIQEMQ 111
+Q +E L R + ++T L++LEE + D+ + M+ +N E + +Q
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL----ERHISTLNIQ 1372
Query: 112 LKEAK----------HIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
L ++K EE +++++ L E A ++ E ++ + ++L
Sbjct: 1373 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
+N + L + EK K D+ E K +S K + RAE R ++
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492
Query: 222 EKLAQAKEENVGLHQTLDQTLNEL 245
E+ +AKEE ++ L + +L
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDL 1516
Score = 50.1 bits (118), Expect = 2e-06
Identities = 49/264 (18%), Positives = 115/264 (43%), Gaps = 21/264 (7%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGE----RERREKAEGDVAALNRRIQLVE 60
N E++ +++ ++ +++ + L+R+L+G+ E+ + +A L ++ E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 61 EELDRAQERLA-------TALQKLEEAEKAADESERGM---KVIENRAMKDE----EKME 106
EEL A RL AL+K+ E E + + + + N+A K + E++E
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 107 IQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL--ERAEERAEVSELKCGDLEEELKNV 164
+ +L++ + +++ +L+ L E A+V E++ + ++ +
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA-VEEL 1208
Query: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224
T L+ + A + + E+E L+ +L+ + E KLE + +L+ K
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 225 AQAKEENVGLHQTLDQTLNELNCI 248
+ + L+ + + NE+ +
Sbjct: 1269 SDGERARAELNDKVHKLQNEVESV 1292
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 14/231 (6%)
Query: 4 LNSLEAVKRKI-QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
+++LE +RK Q L ++ + + A R RE+ KA AL ++ +EE
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE-AKEE 1501
Query: 63 LDRAQERLATALQKL----EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
L+R + L ++ L ++ K E E+ + +E + E+M+ Q +L++
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM----EEMKTQLEELEDELQA 1557
Query: 119 AEEADRKYEEVARKLVILEGELER-AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
E+A + E + L+G+ ER + R E +E K L+ +L L+
Sbjct: 1558 TEDAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 178 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ + K E ++K L + A E A + + KL+ + D + +L A+
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Score = 50.1 bits (118), Expect = 2e-06
Identities = 40/179 (22%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Query: 12 RKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLA 71
+K ++ +QQ + + E++G + K + +AAL +I +EE++++
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAV--KSKFKSTIAALEAKIAQLEEQVEQEAREKQ 1838
Query: 72 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR 131
A + L++ +K E ++ A + +E+ E ++K+ K EEA+ + + +
Sbjct: 1839 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1898
Query: 132 KLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEKEDKYEEE 188
L+ EL+ A E E + L+ +L+ N T+ + S + + E D EEE
Sbjct: 1899 NRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEE 1957
Score = 48.9 bits (115), Expect = 4e-06
Identities = 63/257 (24%), Positives = 113/257 (43%), Gaps = 41/257 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQ-----LVEE 61
LE + Q LQ + AE + + L+ E+ ++ K + L RI L EE
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 62 E--------LDRAQERLATALQ-KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
E L E + + L+ +L++ EK+ E E+ + +E A E++ + Q+
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 113 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E K + +K EE+ L L+ E+ + + K +LE + ++ +L S
Sbjct: 1079 AELK---MQLAKKEEELQAALARLDDEIAQKNNALK----KIRELEGHISDLQEDLDSER 1131
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEA--------ETRAEFAERTVAKLEKTID------ 218
AA K +++ EE++ L +L++ E RA+ E+ V L+K +D
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSH 1190
Query: 219 -----DLEEKLAQAKEE 230
++ +K AQA EE
Sbjct: 1191 EAQVQEMRQKHAQAVEE 1207
Score = 35.0 bits (79), Expect = 0.061
Identities = 25/121 (20%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
+++K+K + L++ + ED ++ + +E+ EK V L R+++ EEE R
Sbjct: 1842 KSLKQKDKKLKEILLQVEDE----RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1897
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
++L+EA ++ + R + ++++ + E + + + + E AD E
Sbjct: 1898 ANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR-SGGRRVIENADGSEE 1956
Query: 128 E 128
E
Sbjct: 1957 E 1957
Score = 33.9 bits (76), Expect = 0.14
Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLV---E 60
L +E ++ + ++QA++ R + L+R+L+ E ++ + L R +
Sbjct: 1855 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEE 103
E + R L + L++ E G +VIEN +EE
Sbjct: 1915 EAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 73.9 bits (180), Expect = 1e-13
Identities = 64/257 (24%), Positives = 112/257 (43%), Gaps = 23/257 (8%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA- 66
+ + +K AL++ E E LQ +LD ER R KAE L ++ ++ EL+
Sbjct: 1108 DEIAQKNNALKK-IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 67 ------QERLATALQKLEEAEKAADESERGMKV-IENRAMKDEEKMEIQEMQLKEAKHIA 119
QE A Q++ +KA DE R + ++ K + +E QL++ K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 179
D+ + + ++ L GEL + + E K LE +++ + + E A + +
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 180 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEE--------------KLA 225
+K K + E++ ++ L EAE +A + VA L + D +E KL
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 226 QAKEENVGLHQTLDQTL 242
Q +EE L LD+ +
Sbjct: 1347 QLEEERNSLQDQLDEEM 1363
Score = 68.9 bits (167), Expect = 4e-12
Identities = 65/255 (25%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 20 QADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 79
Q E+ Q + EL +ER++KAE ++ L ++ + EE + QE+L + E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 80 AEK-----AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE----EADRKYEEVA 130
AE+ AA + E + E A +EE+ Q++Q + K + E + EE A
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 131 RKLVILEGELERAEERAEVSELKCGD------------LEEELKNVTNNLKSLEAASEKY 178
R+ + LE A+ + E+ D LEE + ++T NL E ++
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 179 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE-------KTIDDLEEKLAQAKEEN 231
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++A+ K +
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 232 VGLHQTLDQTLNELN 246
+ L L L+
Sbjct: 1093 AKKEEELQAALARLD 1107
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/243 (22%), Positives = 113/243 (46%), Gaps = 9/243 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQE-- 68
+ ++QA + + + ++R Q + EL ++ + + L ++Q E A+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 69 -RLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
RLA Q+LEE + +E +RG ++ R ++ ++++E QL+E + ++
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 976
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ K+ LE E+ +++ + LEE + ++T NL E ++ ++ +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
+K+E I L +LK+ E + E+ KLE D E++A + + L L +
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 243 NEL 245
EL
Sbjct: 1097 EEL 1099
Score = 65.1 bits (157), Expect = 5e-11
Identities = 56/240 (23%), Positives = 111/240 (46%), Gaps = 14/240 (5%)
Query: 2 AGLNSLEAVKRKIQALQQQAD-EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
A L L+ + ++QAD E E+ A+ L L G R + + L RI +E
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG----RNALQDEKRRLEARIAQLE 1749
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE---EKMEIQEMQLKEAKH 117
EEL+ Q + ++ +A + A++ + + A K+E +++E Q +L+ H
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 118 IAEEADR-KYEE----VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E A + K++ + K+ LE ++E+ + + +++LK + ++
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD-LEEKLAQAKEEN 231
+E+Y E+ +K +K L +L+EAE ++ KL++ +D+ E A +E N
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929
Score = 62.4 bits (150), Expect = 4e-10
Identities = 73/283 (25%), Positives = 135/283 (47%), Gaps = 52/283 (18%)
Query: 6 SLEAVKRKIQA-LQQQADEAEDRAQGLQR-------ELDGERERR-------EKAEGDV- 49
+++A+K + + LQ + ++ E++ + LQR EL+ ER++R +K EGD+
Sbjct: 1575 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1634
Query: 50 -------AALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 102
+A+ R + +++ L + Q ++ ++LE+A + DE K E +A E
Sbjct: 1635 DLELQADSAIKGREEAIKQ-LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 103 -EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI-LEGELERAEERAEVSELKCGDLEEE 160
+ M++QE L A+ ++AD + EE+A +L L G +E+ + E + LEEE
Sbjct: 1694 ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEEE 1751
Query: 161 L---------------------KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 199
L + ++N L + + ++K + E + K L KL E
Sbjct: 1752 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 200 E--TRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +++F + T+A LE I LEE++ Q E ++L Q
Sbjct: 1812 EGAVKSKF-KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/214 (24%), Positives = 107/214 (50%), Gaps = 22/214 (10%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQG-LQRELDGERERREKAE---GDVAALNRRI 56
++G N+L+ KR+++A Q +E + QG ++ D R+ ++AE ++A
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 57 QLVE---EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 113
Q E ++L+R + L + L ++E A K+ +S + +E + + EE++E + + +
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1845
Query: 114 EAKHIAEEADRKYEEVARKLVILEGELERAEE--------RAEVSELK--CGDLEEELKN 163
A ++ D+K +E+ L+ +E E + AE+ A V +LK + EEE +
Sbjct: 1846 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 197
+ N + L+ ++ +E + E+ L KL+
Sbjct: 1903 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 54.7 bits (130), Expect = 7e-08
Identities = 52/238 (21%), Positives = 109/238 (45%), Gaps = 26/238 (10%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E ++ QA+++ ++ E + + LD ++ EK D+A R + ++E++ +
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFKRA-KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1261
Query: 68 ERLATALQKLE----EAEKAADE-------------SERGM-KVIENRAMKDEEKMEIQE 109
++L +Q+L+ + E+A E S GM E +A+K + +
Sbjct: 1262 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 110 MQLKEAKHIAEEADRKYEEVARKLVILEGE-------LERAEERAEVSELKCGDLEEELK 162
QL++ + + +E R+ V+ KL LE E L+ E + E L +L
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 163 NVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ L+ + E E + ++++EI+ L+ + +E + E+T +L++ +DDL
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Score = 52.4 bits (124), Expect = 4e-07
Identities = 48/235 (20%), Positives = 104/235 (44%), Gaps = 14/235 (5%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L ++ + +LQ Q DE + Q L+R + + ++ + ++ +EE R
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Q+ + Q+ EE A D+ E+ +NR ++ + + + ++ E+ RK+
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+++ + + + +RAE E+E K + SL A E+ E +++ E
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAR-----EKETKAL-----SLARALEEALEAKEELE 1510
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
K+L ++++ + + + V +LEK+ LE ++ + K + L L T
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Score = 52.0 bits (123), Expect = 5e-07
Identities = 57/263 (21%), Positives = 119/263 (45%), Gaps = 37/263 (14%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE---L 63
LE + + Q LQ + + + L+ +L+ E R+K + + +I+ +E+E +
Sbjct: 938 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM 997
Query: 64 DRAQERLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
D +L+ + LEE A+E E+ + + +K++ + I E++++ K
Sbjct: 998 DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKE- 1053
Query: 119 AEEADRKYEEVARKLVILEGEL-----ERAEERAEVSELK-------------CGDLEEE 160
E++ ++ E++ RK LEG+ + A+ +A+++ELK L++E
Sbjct: 1054 -EKSRQELEKLKRK---LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 161 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ N LK + S+ ++ + E + K+ E E +LE T+D
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1169
Query: 221 ---EEKLAQAKEENVGLHQTLDQ 240
+E A+ ++E L + LD+
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDE 1192
Score = 50.4 bits (119), Expect = 1e-06
Identities = 59/264 (22%), Positives = 114/264 (43%), Gaps = 32/264 (12%)
Query: 10 VKRKIQALQQQADEAE-------DRAQGLQRELDGERERREKAEG-------DVAALNRR 55
++ ++Q LQ + + E D+ LQ E++ +AEG DVA+L+ +
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 56 IQLVEEELD---RAQERLATALQKLEEAEKAA-DESERGMKVIENRAMKDEEKMEIQEMQ 111
+Q +E L R + ++T L++LEE + D+ + M+ +N E + +Q
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL----ERHISTLNIQ 1379
Query: 112 LKEAK----------HIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
L ++K EE +++++ L E A ++ E ++ + ++L
Sbjct: 1380 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
+N + L + EK K D+ E K +S K + RAE R ++
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499
Query: 222 EKLAQAKEENVGLHQTLDQTLNEL 245
E+ +AKEE ++ L + +L
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDL 1523
Score = 50.1 bits (118), Expect = 2e-06
Identities = 49/264 (18%), Positives = 115/264 (43%), Gaps = 21/264 (7%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGE----RERREKAEGDVAALNRRIQLVE 60
N E++ +++ ++ +++ + L+R+L+G+ E+ + +A L ++ E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 61 EELDRAQERLA-------TALQKLEEAEKAADESERGM---KVIENRAMKDE----EKME 106
EEL A RL AL+K+ E E + + + + N+A K + E++E
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 107 IQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL--ERAEERAEVSELKCGDLEEELKNV 164
+ +L++ + +++ +L+ L E A+V E++ + ++ +
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA-VEEL 1215
Query: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224
T L+ + A + + E+E L+ +L+ + E KLE + +L+ K
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 225 AQAKEENVGLHQTLDQTLNELNCI 248
+ + L+ + + NE+ +
Sbjct: 1276 SDGERARAELNDKVHKLQNEVESV 1299
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 14/231 (6%)
Query: 4 LNSLEAVKRKI-QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
+++LE +RK Q L ++ + + A R RE+ KA AL ++ +EE
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE-AKEE 1508
Query: 63 LDRAQERLATALQKL----EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
L+R + L ++ L ++ K E E+ + +E + E+M+ Q +L++
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM----EEMKTQLEELEDELQA 1564
Query: 119 AEEADRKYEEVARKLVILEGELER-AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
E+A + E + L+G+ ER + R E +E K L+ +L L+
Sbjct: 1565 TEDAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 178 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ + K E ++K L + A E A + + KL+ + D + +L A+
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Score = 50.1 bits (118), Expect = 2e-06
Identities = 40/179 (22%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Query: 12 RKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLA 71
+K ++ +QQ + + E++G + K + +AAL +I +EE++++
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAV--KSKFKSTIAALEAKIAQLEEQVEQEAREKQ 1845
Query: 72 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR 131
A + L++ +K E ++ A + +E+ E ++K+ K EEA+ + + +
Sbjct: 1846 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1905
Query: 132 KLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEKEDKYEEE 188
L+ EL+ A E E + L+ +L+ N T+ + S + + E D EEE
Sbjct: 1906 NRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEE 1964
Score = 48.9 bits (115), Expect = 4e-06
Identities = 63/257 (24%), Positives = 113/257 (43%), Gaps = 41/257 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQ-----LVEE 61
LE + Q LQ + AE + + L+ E+ ++ K + L RI L EE
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 62 E--------LDRAQERLATALQ-KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
E L E + + L+ +L++ EK+ E E+ + +E A E++ + Q+
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 113 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E K + +K EE+ L L+ E+ + + K +LE + ++ +L S
Sbjct: 1086 AELK---MQLAKKEEELQAALARLDDEIAQKNNALK----KIRELEGHISDLQEDLDSER 1138
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEA--------ETRAEFAERTVAKLEKTID------ 218
AA K +++ EE++ L +L++ E RA+ E+ V L+K +D
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSH 1197
Query: 219 -----DLEEKLAQAKEE 230
++ +K AQA EE
Sbjct: 1198 EAQVQEMRQKHAQAVEE 1214
Score = 35.0 bits (79), Expect = 0.061
Identities = 25/121 (20%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
+++K+K + L++ + ED ++ + +E+ EK V L R+++ EEE R
Sbjct: 1849 KSLKQKDKKLKEILLQVEDE----RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1904
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
++L+EA ++ + R + ++++ + E + + + + E AD E
Sbjct: 1905 ANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR-SGGRRVIENADGSEE 1963
Query: 128 E 128
E
Sbjct: 1964 E 1964
Score = 33.9 bits (76), Expect = 0.14
Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLV---E 60
L +E ++ + ++QA++ R + L+R+L+ E ++ + L R +
Sbjct: 1862 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEE 103
E + R L + L++ E G +VIEN +EE
Sbjct: 1922 EAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 73.9 bits (180), Expect = 1e-13
Identities = 64/257 (24%), Positives = 112/257 (43%), Gaps = 23/257 (8%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA- 66
+ + +K AL++ E E LQ +LD ER R KAE L ++ ++ EL+
Sbjct: 1108 DEIAQKNNALKK-IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 67 ------QERLATALQKLEEAEKAADESERGMKV-IENRAMKDEEKMEIQEMQLKEAKHIA 119
QE A Q++ +KA DE R + ++ K + +E QL++ K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 179
D+ + + ++ L GEL + + E K LE +++ + + E A + +
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 180 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEE--------------KLA 225
+K K + E++ ++ L EAE +A + VA L + D +E KL
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 226 QAKEENVGLHQTLDQTL 242
Q +EE L LD+ +
Sbjct: 1347 QLEEERNSLQDQLDEEM 1363
Score = 68.9 bits (167), Expect = 4e-12
Identities = 65/255 (25%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 20 QADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 79
Q E+ Q + EL +ER++KAE ++ L ++ + EE + QE+L + E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 80 AEK-----AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE----EADRKYEEVA 130
AE+ AA + E + E A +EE+ Q++Q + K + E + EE A
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 131 RKLVILEGELERAEERAEVSELKCGD------------LEEELKNVTNNLKSLEAASEKY 178
R+ + LE A+ + E+ D LEE + ++T NL E ++
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 179 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE-------KTIDDLEEKLAQAKEEN 231
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++A+ K +
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 232 VGLHQTLDQTLNELN 246
+ L L L+
Sbjct: 1093 AKKEEELQAALARLD 1107
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/243 (22%), Positives = 113/243 (46%), Gaps = 9/243 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQE-- 68
+ ++QA + + + ++R Q + EL ++ + + L ++Q E A+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 69 -RLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
RLA Q+LEE + +E +RG ++ R ++ ++++E QL+E + ++
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 976
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ K+ LE E+ +++ + LEE + ++T NL E ++ ++ +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
+K+E I L +LK+ E + E+ KLE D E++A + + L L +
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 243 NEL 245
EL
Sbjct: 1097 EEL 1099
Score = 65.1 bits (157), Expect = 5e-11
Identities = 56/240 (23%), Positives = 111/240 (46%), Gaps = 14/240 (5%)
Query: 2 AGLNSLEAVKRKIQALQQQAD-EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
A L L+ + ++QAD E E+ A+ L L G R + + L RI +E
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG----RNALQDEKRRLEARIAQLE 1749
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE---EKMEIQEMQLKEAKH 117
EEL+ Q + ++ +A + A++ + + A K+E +++E Q +L+ H
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 118 IAEEADR-KYEE----VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E A + K++ + K+ LE ++E+ + + +++LK + ++
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD-LEEKLAQAKEEN 231
+E+Y E+ +K +K L +L+EAE ++ KL++ +D+ E A +E N
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929
Score = 62.4 bits (150), Expect = 4e-10
Identities = 73/283 (25%), Positives = 135/283 (47%), Gaps = 52/283 (18%)
Query: 6 SLEAVKRKIQA-LQQQADEAEDRAQGLQR-------ELDGERERR-------EKAEGDV- 49
+++A+K + + LQ + ++ E++ + LQR EL+ ER++R +K EGD+
Sbjct: 1575 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1634
Query: 50 -------AALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 102
+A+ R + +++ L + Q ++ ++LE+A + DE K E +A E
Sbjct: 1635 DLELQADSAIKGREEAIKQ-LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 103 -EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI-LEGELERAEERAEVSELKCGDLEEE 160
+ M++QE L A+ ++AD + EE+A +L L G +E+ + E + LEEE
Sbjct: 1694 ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEEE 1751
Query: 161 L---------------------KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 199
L + ++N L + + ++K + E + K L KL E
Sbjct: 1752 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 200 E--TRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +++F + T+A LE I LEE++ Q E ++L Q
Sbjct: 1812 EGAVKSKF-KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/214 (24%), Positives = 107/214 (50%), Gaps = 22/214 (10%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQG-LQRELDGERERREKAE---GDVAALNRRI 56
++G N+L+ KR+++A Q +E + QG ++ D R+ ++AE ++A
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 57 QLVE---EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 113
Q E ++L+R + L + L ++E A K+ +S + +E + + EE++E + + +
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1845
Query: 114 EAKHIAEEADRKYEEVARKLVILEGELERAEE--------RAEVSELK--CGDLEEELKN 163
A ++ D+K +E+ L+ +E E + AE+ A V +LK + EEE +
Sbjct: 1846 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 197
+ N + L+ ++ +E + E+ L KL+
Sbjct: 1903 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 54.7 bits (130), Expect = 7e-08
Identities = 52/238 (21%), Positives = 109/238 (45%), Gaps = 26/238 (10%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E ++ QA+++ ++ E + + LD ++ EK D+A R + ++E++ +
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFKRA-KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1261
Query: 68 ERLATALQKLE----EAEKAADE-------------SERGM-KVIENRAMKDEEKMEIQE 109
++L +Q+L+ + E+A E S GM E +A+K + +
Sbjct: 1262 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 110 MQLKEAKHIAEEADRKYEEVARKLVILEGE-------LERAEERAEVSELKCGDLEEELK 162
QL++ + + +E R+ V+ KL LE E L+ E + E L +L
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 163 NVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ L+ + E E + ++++EI+ L+ + +E + E+T +L++ +DDL
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Score = 52.4 bits (124), Expect = 4e-07
Identities = 48/235 (20%), Positives = 104/235 (44%), Gaps = 14/235 (5%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L ++ + +LQ Q DE + Q L+R + + ++ + ++ +EE R
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Q+ + Q+ EE A D+ E+ +NR ++ + + + ++ E+ RK+
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+++ + + + +RAE E+E K + SL A E+ E +++ E
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAR-----EKETKAL-----SLARALEEALEAKEELE 1510
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
K+L ++++ + + + V +LEK+ LE ++ + K + L L T
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Score = 52.0 bits (123), Expect = 5e-07
Identities = 57/263 (21%), Positives = 119/263 (45%), Gaps = 37/263 (14%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE---L 63
LE + + Q LQ + + + L+ +L+ E R+K + + +I+ +E+E +
Sbjct: 938 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM 997
Query: 64 DRAQERLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
D +L+ + LEE A+E E+ + + +K++ + I E++++ K
Sbjct: 998 DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKE- 1053
Query: 119 AEEADRKYEEVARKLVILEGEL-----ERAEERAEVSELK-------------CGDLEEE 160
E++ ++ E++ RK LEG+ + A+ +A+++ELK L++E
Sbjct: 1054 -EKSRQELEKLKRK---LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 161 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ N LK + S+ ++ + E + K+ E E +LE T+D
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1169
Query: 221 ---EEKLAQAKEENVGLHQTLDQ 240
+E A+ ++E L + LD+
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDE 1192
Score = 50.4 bits (119), Expect = 1e-06
Identities = 59/264 (22%), Positives = 114/264 (43%), Gaps = 32/264 (12%)
Query: 10 VKRKIQALQQQADEAE-------DRAQGLQRELDGERERREKAEG-------DVAALNRR 55
++ ++Q LQ + + E D+ LQ E++ +AEG DVA+L+ +
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 56 IQLVEEELD---RAQERLATALQKLEEAEKAA-DESERGMKVIENRAMKDEEKMEIQEMQ 111
+Q +E L R + ++T L++LEE + D+ + M+ +N E + +Q
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL----ERHISTLNIQ 1379
Query: 112 LKEAK----------HIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
L ++K EE +++++ L E A ++ E ++ + ++L
Sbjct: 1380 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
+N + L + EK K D+ E K +S K + RAE R ++
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499
Query: 222 EKLAQAKEENVGLHQTLDQTLNEL 245
E+ +AKEE ++ L + +L
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDL 1523
Score = 50.1 bits (118), Expect = 2e-06
Identities = 49/264 (18%), Positives = 115/264 (43%), Gaps = 21/264 (7%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGE----RERREKAEGDVAALNRRIQLVE 60
N E++ +++ ++ +++ + L+R+L+G+ E+ + +A L ++ E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 61 EELDRAQERLA-------TALQKLEEAEKAADESERGM---KVIENRAMKDE----EKME 106
EEL A RL AL+K+ E E + + + + N+A K + E++E
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 107 IQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL--ERAEERAEVSELKCGDLEEELKNV 164
+ +L++ + +++ +L+ L E A+V E++ + ++ +
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA-VEEL 1215
Query: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224
T L+ + A + + E+E L+ +L+ + E KLE + +L+ K
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 225 AQAKEENVGLHQTLDQTLNELNCI 248
+ + L+ + + NE+ +
Sbjct: 1276 SDGERARAELNDKVHKLQNEVESV 1299
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 14/231 (6%)
Query: 4 LNSLEAVKRKI-QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
+++LE +RK Q L ++ + + A R RE+ KA AL ++ +EE
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE-AKEE 1508
Query: 63 LDRAQERLATALQKL----EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
L+R + L ++ L ++ K E E+ + +E + E+M+ Q +L++
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM----EEMKTQLEELEDELQA 1564
Query: 119 AEEADRKYEEVARKLVILEGELER-AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
E+A + E + L+G+ ER + R E +E K L+ +L L+
Sbjct: 1565 TEDAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 178 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ + K E ++K L + A E A + + KL+ + D + +L A+
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Score = 48.9 bits (115), Expect = 4e-06
Identities = 63/257 (24%), Positives = 113/257 (43%), Gaps = 41/257 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQ-----LVEE 61
LE + Q LQ + AE + + L+ E+ ++ K + L RI L EE
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 62 E--------LDRAQERLATALQ-KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
E L E + + L+ +L++ EK+ E E+ + +E A E++ + Q+
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 113 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E K + +K EE+ L L+ E+ + + K +LE + ++ +L S
Sbjct: 1086 AELK---MQLAKKEEELQAALARLDDEIAQKNNALK----KIRELEGHISDLQEDLDSER 1138
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEA--------ETRAEFAERTVAKLEKTID------ 218
AA K +++ EE++ L +L++ E RA+ E+ V L+K +D
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSH 1197
Query: 219 -----DLEEKLAQAKEE 230
++ +K AQA EE
Sbjct: 1198 EAQVQEMRQKHAQAVEE 1214
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 73.9 bits (180), Expect = 1e-13
Identities = 64/257 (24%), Positives = 112/257 (43%), Gaps = 23/257 (8%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA- 66
+ + +K AL++ E E LQ +LD ER R KAE L ++ ++ EL+
Sbjct: 1101 DEIAQKNNALKK-IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 67 ------QERLATALQKLEEAEKAADESERGMKV-IENRAMKDEEKMEIQEMQLKEAKHIA 119
QE A Q++ +KA DE R + ++ K + +E QL++ K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 179
D+ + + ++ L GEL + + E K LE +++ + + E A + +
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1279
Query: 180 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEE--------------KLA 225
+K K + E++ ++ L EAE +A + VA L + D +E KL
Sbjct: 1280 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1339
Query: 226 QAKEENVGLHQTLDQTL 242
Q +EE L LD+ +
Sbjct: 1340 QLEEERNSLQDQLDEEM 1356
Score = 68.9 bits (167), Expect = 4e-12
Identities = 65/255 (25%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 20 QADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 79
Q E+ Q + EL +ER++KAE ++ L ++ + EE + QE+L + E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 80 AEK-----AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE----EADRKYEEVA 130
AE+ AA + E + E A +EE+ Q++Q + K + E + EE A
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 131 RKLVILEGELERAEERAEVSELKCGD------------LEEELKNVTNNLKSLEAASEKY 178
R+ + LE A+ + E+ D LEE + ++T NL E ++
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 179 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE-------KTIDDLEEKLAQAKEEN 231
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++A+ K +
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 232 VGLHQTLDQTLNELN 246
+ L L L+
Sbjct: 1086 AKKEEELQAALARLD 1100
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/243 (22%), Positives = 113/243 (46%), Gaps = 9/243 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQE-- 68
+ ++QA + + + ++R Q + EL ++ + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 69 -RLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
RLA Q+LEE + +E +RG ++ R ++ ++++E QL+E + ++
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 969
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ K+ LE E+ +++ + LEE + ++T NL E ++ ++ +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
+K+E I L +LK+ E + E+ KLE D E++A + + L L +
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 243 NEL 245
EL
Sbjct: 1090 EEL 1092
Score = 65.1 bits (157), Expect = 5e-11
Identities = 56/240 (23%), Positives = 111/240 (46%), Gaps = 14/240 (5%)
Query: 2 AGLNSLEAVKRKIQALQQQAD-EAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
A L L+ + ++QAD E E+ A+ L L G R + + L RI +E
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG----RNALQDEKRRLEARIAQLE 1742
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE---EKMEIQEMQLKEAKH 117
EEL+ Q + ++ +A + A++ + + A K+E +++E Q +L+ H
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 118 IAEEADR-KYEE----VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E A + K++ + K+ LE ++E+ + + +++LK + ++
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD-LEEKLAQAKEEN 231
+E+Y E+ +K +K L +L+EAE ++ KL++ +D+ E A +E N
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1922
Score = 62.4 bits (150), Expect = 4e-10
Identities = 73/283 (25%), Positives = 135/283 (47%), Gaps = 52/283 (18%)
Query: 6 SLEAVKRKIQA-LQQQADEAEDRAQGLQR-------ELDGERERR-------EKAEGDV- 49
+++A+K + + LQ + ++ E++ + LQR EL+ ER++R +K EGD+
Sbjct: 1568 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
Query: 50 -------AALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 102
+A+ R + +++ L + Q ++ ++LE+A + DE K E +A E
Sbjct: 1628 DLELQADSAIKGREEAIKQ-LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 103 -EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI-LEGELERAEERAEVSELKCGDLEEE 160
+ M++QE L A+ ++AD + EE+A +L L G +E+ + E + LEEE
Sbjct: 1687 ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEEE 1744
Query: 161 L---------------------KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 199
L + ++N L + + ++K + E + K L KL E
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 200 E--TRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E +++F + T+A LE I LEE++ Q E ++L Q
Sbjct: 1805 EGAVKSKF-KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/214 (24%), Positives = 107/214 (50%), Gaps = 22/214 (10%)
Query: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQG-LQRELDGERERREKAE---GDVAALNRRI 56
++G N+L+ KR+++A Q +E + QG ++ D R+ ++AE ++A
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 57 QLVE---EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 113
Q E ++L+R + L + L ++E A K+ +S + +E + + EE++E + + +
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1838
Query: 114 EAKHIAEEADRKYEEVARKLVILEGELERAEE--------RAEVSELK--CGDLEEELKN 163
A ++ D+K +E+ L+ +E E + AE+ A V +LK + EEE +
Sbjct: 1839 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 197
+ N + L+ ++ +E + E+ L KL+
Sbjct: 1896 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 54.7 bits (130), Expect = 7e-08
Identities = 52/238 (21%), Positives = 109/238 (45%), Gaps = 26/238 (10%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E ++ QA+++ ++ E + + LD ++ EK D+A R + ++E++ +
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFKRA-KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Query: 68 ERLATALQKLE----EAEKAADE-------------SERGM-KVIENRAMKDEEKMEIQE 109
++L +Q+L+ + E+A E S GM E +A+K + +
Sbjct: 1255 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 110 MQLKEAKHIAEEADRKYEEVARKLVILEGE-------LERAEERAEVSELKCGDLEEELK 162
QL++ + + +E R+ V+ KL LE E L+ E + E L +L
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 163 NVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ L+ + E E + ++++EI+ L+ + +E + E+T +L++ +DDL
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Score = 52.4 bits (124), Expect = 4e-07
Identities = 48/235 (20%), Positives = 104/235 (44%), Gaps = 14/235 (5%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
L ++ + +LQ Q DE + Q L+R + + ++ + ++ +EE R
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Q+ + Q+ EE A D+ E+ +NR ++ + + + ++ E+ RK+
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+++ + + + +RAE E+E K + SL A E+ E +++ E
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAR-----EKETKAL-----SLARALEEALEAKEELE 1503
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
K+L ++++ + + + V +LEK+ LE ++ + K + L L T
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Score = 52.0 bits (123), Expect = 5e-07
Identities = 57/263 (21%), Positives = 119/263 (45%), Gaps = 37/263 (14%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE---L 63
LE + + Q LQ + + + L+ +L+ E R+K + + +I+ +E+E +
Sbjct: 931 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM 990
Query: 64 DRAQERLATALQKLEE-----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
D +L+ + LEE A+E E+ + + +K++ + I E++++ K
Sbjct: 991 DDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKE- 1046
Query: 119 AEEADRKYEEVARKLVILEGEL-----ERAEERAEVSELK-------------CGDLEEE 160
E++ ++ E++ RK LEG+ + A+ +A+++ELK L++E
Sbjct: 1047 -EKSRQELEKLKRK---LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 161 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 220
+ N LK + S+ ++ + E + K+ E E +LE T+D
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 221 ---EEKLAQAKEENVGLHQTLDQ 240
+E A+ ++E L + LD+
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDE 1185
Score = 50.4 bits (119), Expect = 1e-06
Identities = 59/264 (22%), Positives = 114/264 (43%), Gaps = 32/264 (12%)
Query: 10 VKRKIQALQQQADEAE-------DRAQGLQRELDGERERREKAEG-------DVAALNRR 55
++ ++Q LQ + + E D+ LQ E++ +AEG DVA+L+ +
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 56 IQLVEEELD---RAQERLATALQKLEEAEKAA-DESERGMKVIENRAMKDEEKMEIQEMQ 111
+Q +E L R + ++T L++LEE + D+ + M+ +N E + +Q
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL----ERHISTLNIQ 1372
Query: 112 LKEAK----------HIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
L ++K EE +++++ L E A ++ E ++ + ++L
Sbjct: 1373 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
+N + L + EK K D+ E K +S K + RAE R ++
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492
Query: 222 EKLAQAKEENVGLHQTLDQTLNEL 245
E+ +AKEE ++ L + +L
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDL 1516
Score = 50.1 bits (118), Expect = 2e-06
Identities = 49/264 (18%), Positives = 115/264 (43%), Gaps = 21/264 (7%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGE----RERREKAEGDVAALNRRIQLVE 60
N E++ +++ ++ +++ + L+R+L+G+ E+ + +A L ++ E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 61 EELDRAQERLA-------TALQKLEEAEKAADESERGM---KVIENRAMKDE----EKME 106
EEL A RL AL+K+ E E + + + + N+A K + E++E
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 107 IQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL--ERAEERAEVSELKCGDLEEELKNV 164
+ +L++ + +++ +L+ L E A+V E++ + ++ +
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA-VEEL 1208
Query: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224
T L+ + A + + E+E L+ +L+ + E KLE + +L+ K
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 225 AQAKEENVGLHQTLDQTLNELNCI 248
+ + L+ + + NE+ +
Sbjct: 1269 SDGERARAELNDKVHKLQNEVESV 1292
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 14/231 (6%)
Query: 4 LNSLEAVKRKI-QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
+++LE +RK Q L ++ + + A R RE+ KA AL ++ +EE
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE-AKEE 1501
Query: 63 LDRAQERLATALQKL----EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 118
L+R + L ++ L ++ K E E+ + +E + E+M+ Q +L++
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM----EEMKTQLEELEDELQA 1557
Query: 119 AEEADRKYEEVARKLVILEGELER-AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
E+A + E + L+G+ ER + R E +E K L+ +L L+
Sbjct: 1558 TEDAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 178 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
+ + K E ++K L + A E A + + KL+ + D + +L A+
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Score = 48.9 bits (115), Expect = 4e-06
Identities = 63/257 (24%), Positives = 113/257 (43%), Gaps = 41/257 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQ-----LVEE 61
LE + Q LQ + AE + + L+ E+ ++ K + L RI L EE
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 62 E--------LDRAQERLATALQ-KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 112
E L E + + L+ +L++ EK+ E E+ + +E A E++ + Q+
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 113 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 172
E K + +K EE+ L L+ E+ + + K +LE + ++ +L S
Sbjct: 1079 AELK---MQLAKKEEELQAALARLDDEIAQKNNALK----KIRELEGHISDLQEDLDSER 1131
Query: 173 AASEKYSEKEDKYEEEIKLLSDKLKEA--------ETRAEFAERTVAKLEKTID------ 218
AA K +++ EE++ L +L++ E RA+ E+ V L+K +D
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSH 1190
Query: 219 -----DLEEKLAQAKEE 230
++ +K AQA EE
Sbjct: 1191 EAQVQEMRQKHAQAVEE 1207
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 73.6 bits (179), Expect = 2e-13
Identities = 47/219 (21%), Positives = 110/219 (50%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E + R+ + +++Q + + + ++E E E+R++ E + +I+ EE++ R +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E++ +K +E E+ + E ++ E + + EEK+ QE +++E + + +E + K
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
E K+ E +++ EE E K + E++++ ++ E ++ EK + EE
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 226
++ +K++E E + E + + E + EEK+ +
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 68.2 bits (165), Expect = 6e-12
Identities = 47/223 (21%), Positives = 107/223 (47%), Gaps = 7/223 (3%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E V R+ + +++Q ++ ++ + + R+ + RE+ E + + EE+ +
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
+++ +K+ E E+ E ++ E + + EEKM QE +++E + +E + K
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
E E ++ EE + E K G+ EE++ ++ E + EK + E+
Sbjct: 630 E-------QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+I+ +K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 66.6 bits (161), Expect = 2e-11
Identities = 54/217 (24%), Positives = 100/217 (46%), Gaps = 19/217 (8%)
Query: 15 QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATAL 74
Q LQ +AD Q + +L + E E NR Q EE++ R +E++
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENE-------LWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 75 QKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLV 134
+K++E E+ E E ++ E + + EE M +E +++ + + E + K +
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 135 ILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLL-S 193
E ++ R EE E K +LEE++ EK E+E+K +EE K+
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHE-----------QEKIREQEEKRQEEEKIREQ 422
Query: 194 DKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+K +E E + E + + E+ I + E+K+ + +E+
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Score = 66.2 bits (160), Expect = 2e-11
Identities = 60/233 (25%), Positives = 109/233 (46%), Gaps = 28/233 (12%)
Query: 18 QQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKL 77
Q++ E E++ Q + E E+E+R++ E + +I+ EE++ ++++ +K+
Sbjct: 403 QEKIREQEEKRQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQE--MQLKEAKHIAEEADRKYEEVARKLVI 135
E EK +E +R + + EEK+ QE + KE H EE RK EE K+
Sbjct: 461 HEQEKIREEEKRQE---QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE---KVWR 514
Query: 136 LEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEA--------ASEKYSEKEDK--- 184
E ++ EE+ E K EE+++ + E EK E+EDK
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 185 -------YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
EE++ +K++E E + + E + K E+ I + EEK+ + +E+
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Score = 65.9 bits (159), Expect = 3e-11
Identities = 51/235 (21%), Positives = 114/235 (48%), Gaps = 7/235 (2%)
Query: 11 KRKIQALQQQADEAEDRAQGLQREL-DGERERREKAEGDVAALNRRIQLV--EEELDRAQ 67
+ KI+ +++ E E + + ++ + E+ R E+ + + R+ + + +EE+ R +
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E++ +K+ + E+ E ++ E + + EEKM QE +++E + + E ++ +E
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 128 EVA----RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 183
+ K E ++ R EE+ E K EE+++ + E K EK
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 184 KYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTL 238
+ EE+I+ +K++E E + E + E+ + + EEK+ + +E+ +T+
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Score = 63.5 bits (153), Expect = 2e-10
Identities = 55/232 (23%), Positives = 110/232 (47%), Gaps = 13/232 (5%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKA---EGDVAALNRRIQLVEEELD 64
E KR+ Q + +E + + R+ + E+ EK E V +I+ EE++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEAD 123
+E++ +K+ E E+ E E K+ E + +EEK + QE ++ ++ + I E+ +
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEE---KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEE 584
Query: 124 R------KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
+ K E K E ++ + EE+ E K + EE+++ ++ E +++
Sbjct: 585 KVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 178 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
EK + EE++ +K++E E E + + EK I + EEK+ + +E
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Score = 57.4 bits (137), Expect = 1e-08
Identities = 58/241 (24%), Positives = 109/241 (45%), Gaps = 31/241 (12%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQE-- 68
+ K++ ++ E E++ + L+ ++ + + RE+ E + EEE R QE
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----------KRQEEEKIREQEKR 425
Query: 69 -----RLATALQKLEEAEKAADESERGM-----KVIENRAMKDEEKMEIQEMQLKEAKHI 118
++ +K+ E E+ E E+ M K+ E +++EEK + QE ++ + I
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 119 AEEAD-----RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE- 172
E+ + K E K+ E ++ R EE+ E K + EE++ ++ E
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 173 --AASEKYSEKEDKYEEEIKL-LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
EK E+E +EEE + DK+ E + E V + E+ I + EEK + +E
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Query: 230 E 230
+
Sbjct: 606 K 606
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/227 (22%), Positives = 100/227 (44%), Gaps = 7/227 (3%)
Query: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
+ KIQ +++ E E++ + + ++ + E+ + E + +++ EE + +E++
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 71 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKM----EIQEMQLKEAKHIAEEADRKY 126
+ + E E+ E M E + + EEKM +I+E + K + K
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEE---ELKNVTNNLKSLEAASEKYSEKED 183
+E K+ E ++ EE+ E K EE E + + K E E++
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 184 KYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+EEI +K+ E E + E V + E+ I + EEK+ + +E+
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/171 (21%), Positives = 83/171 (48%), Gaps = 4/171 (2%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
E V R+ + +++Q ++ +++ + + ++ + RE+ EK + + + + + E+ + Q
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
E+ +K+ E E+ E E M+ E + EEK+ QE +++E + E + +
Sbjct: 644 EQE----EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Query: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKY 178
E K+ E ++ EE+ + E K EE++ L+ E +++
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/227 (21%), Positives = 96/227 (42%), Gaps = 9/227 (3%)
Query: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
+L AV + + + +E L EL E+ + A L ++QLVE E
Sbjct: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA--D 123
Q + +KLE A+ + + +A D E+Q + K + E +
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 183
R ++ K+ E +++ EE+ + E K + EE+++ ++ E + EK
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 184 KYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+ EE + +K++ E E + + E+ + + EEK+ + +E+
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Score = 35.4 bits (80), Expect = 0.046
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 23/161 (14%)
Query: 78 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 137
E+ +KA+ + + ++ + + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 164
Query: 138 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 187
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 165 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 218 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 255
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 71.6 bits (174), Expect = 6e-13
Identities = 49/222 (22%), Positives = 111/222 (50%), Gaps = 4/222 (1%)
Query: 13 KIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRR-IQLVEEELDRAQERLA 71
+I+ L+QQ ++ + +G + E + +E+ K + D+ IQ ++EEL L
Sbjct: 1037 QIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLD 1096
Query: 72 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE---E 128
+Q + E ++A E +G+ + + + E +E Q+++ + + ++ K +
Sbjct: 1097 VQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILK 1156
Query: 129 VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEE 188
+ R L + L+ + + + +K L+EE+ +TNNL+ ++ + E+E+ +E
Sbjct: 1157 LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQE 1216
Query: 189 IKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 230
+ L ++L + R + + + + E+ DL+EKL AK++
Sbjct: 1217 TEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQ 1258
Score = 58.5 bits (140), Expect = 5e-09
Identities = 60/242 (24%), Positives = 111/242 (45%), Gaps = 31/242 (12%)
Query: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
+K +I L + + Q + E + R+ EK + +++A + R Q ++ +L R +E
Sbjct: 1185 LKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEED 1244
Query: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKM---EIQEMQLKEAKHIAEEADRKY 126
A +KL +A+K + ++ + V M+DE+K+ +I E++ K+ ++E D K
Sbjct: 1245 YADLKEKLTDAKKQIKQVQKEVSV-----MRDEDKLLRIKINELE-KKKNQCSQELDMKQ 1298
Query: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
+ + L + + EE + E C DL + K + + +LE E+E
Sbjct: 1299 RTIQQLKEQLNNQ--KVEEAIQQYERACKDLNVKEKIIEDMRMTLE-------EQEQTQV 1349
Query: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEK---TIDDLEEKLAQAKEENVGLHQTLDQTLN 243
E+ ++L KL+E E R +LEK +DLE K Q + H+ L
Sbjct: 1350 EQDQVLEAKLEEVE-------RLATELEKWKEKCNDLETKNNQRSNKE---HENNTDVLG 1399
Query: 244 EL 245
+L
Sbjct: 1400 KL 1401
Score = 50.8 bits (120), Expect = 1e-06
Identities = 55/261 (21%), Positives = 115/261 (44%), Gaps = 23/261 (8%)
Query: 5 NSLEAVKRKIQALQQQADEAEDRAQGL----QRELDGERERREKAEGDVAALNRRIQLVE 60
N + +K K +QQ +E +++ L Q ++G+R E +G V +I+ +E
Sbjct: 1069 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQG-VTCYKAKIKELE 1127
Query: 61 EELDRAQ---ERLATALQKLEEAEKAADESERGMKVIENR---AMKDEEKMEIQEMQLKE 114
L+ + A Q + E E + ER +K + ++K+ + + ++E++LKE
Sbjct: 1128 TILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKE 1187
Query: 115 A-----------KHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKN 163
KH+ + + + E ++ L+ EL + R + + EE+ +
Sbjct: 1188 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1247
Query: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
+ L + ++ ++ +E KLL K+ E E + + + ++TI L+E+
Sbjct: 1248 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1307
Query: 224 LAQAK-EENVGLHQTLDQTLN 243
L K EE + ++ + LN
Sbjct: 1308 LNNQKVEEAIQQYERACKDLN 1328
Score = 41.6 bits (96), Expect = 6e-04
Identities = 50/246 (20%), Positives = 108/246 (43%), Gaps = 22/246 (8%)
Query: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRI---QLVEEELD 64
+ +K I + Q+ D + Q L+ ++ + +KA+ +N ++ + VE D
Sbjct: 724 QRIKELINIIDQKEDTINE-FQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKD 782
Query: 65 RAQERLATALQKLEEAEKAADE--SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
++ ++ + +++ E E DE +++G + + +D++K E + E + I
Sbjct: 783 -SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQ 841
Query: 123 DRKYEEVARKLVILEGELERA-EERAEV-------------SELKCGDLEEELKNVTNNL 168
+ E + L+ +E EL+ EE+AE+ SE K L +E++ + +N
Sbjct: 842 ENN-EGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNY 900
Query: 169 KSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 228
A K + EE+I LS++++ A + + ID+L + ++
Sbjct: 901 DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQ 960
Query: 229 EENVGL 234
N+ L
Sbjct: 961 ISNIDL 966
Score = 30.8 bits (68), Expect = 1.1
Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Query: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA--ETRAEFAERTVAKLEKTIDD 219
+N +L E E+ E+ E KLL + L + E +A + KL I+D
Sbjct: 523 ENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIED 582
Query: 220 LEEKLAQAKEENVGL 234
L++KL K+E + L
Sbjct: 583 LKKKLINEKKEKLTL 597
Score = 28.5 bits (62), Expect = 5.7
Identities = 26/123 (21%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Query: 77 LEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA----DRKYEEVARK 132
L+E E + +ER + + ++ K + + E + + K EEA + K+ ++ +
Sbjct: 625 LQEREILEENAERRLAIFKDLVGKCDTREEAAK-DICATKVETEEATACLELKFNQIKAE 683
Query: 133 LVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLL 192
L +GEL + +E + E + L +E LE +++K + + +E I ++
Sbjct: 684 LAKTKGELIKTKEELKKRENESDSLIQE----------LETSNKKIITQNQRIKELINII 733
Query: 193 SDK 195
K
Sbjct: 734 DQK 736
Score = 28.1 bits (61), Expect = 7.4
Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 20 QADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 79
QA EAE+ ++ +RER K + ++ L ++ + +L + +E + LE
Sbjct: 1432 QAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEI 1491
Query: 80 AEKAADES--ERGMKVIE-NRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEE 128
KA S ++ ++ + R + + K+E Q M +K + + + D+ E
Sbjct: 1492 QLKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTE 1543
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 69.3 bits (168), Expect = 3e-12
Identities = 62/278 (22%), Positives = 118/278 (42%), Gaps = 44/278 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVA-------ALNRRIQLV 59
LEA +++I+ L+ + + +A + REL G + + +++ L + +Q++
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIA 119
+E+ A E + + ++E + E ++ + K E + E + +E
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 120 EE---ADRKYEEVARKLVILEGE----LERAEERAEVSELKCGDLEEELKNVTNNL---- 168
E+ A K E +++ + G+ L + + + E +L+ +L N
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 169 KSLE----AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA------------------ 206
KS+E A + E K+EEE K L KL + E + E +
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSET 990
Query: 207 ----ERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E + L+KT+ D E+KL A+EEN GL Q L++
Sbjct: 991 KTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1028
Score = 64.7 bits (156), Expect = 7e-11
Identities = 57/244 (23%), Positives = 111/244 (45%), Gaps = 11/244 (4%)
Query: 3 GLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
G + E + K Q + + D + + LQ + D ER K ++ AL ++ V +E
Sbjct: 604 GTETAEFAELKTQIEKMRLDYQHE-IENLQNQQDSERAAHAK---EMEALRAKLMKVIKE 659
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
+ + E + + L K E+ E E + ++ +K +E +E+ + + E + +
Sbjct: 660 KENSLEAIRSKLDKAEDQHLV--EMEDTLNKLQEAEIKVKE-LEVLQAKCNEQTKVIDNF 716
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ + KL+ L+ L +A + SE+K L ++L+ +K LE S K
Sbjct: 717 TSQLKATEEKLLDLDA-LRKASSEGK-SEMK--KLRQQLEAAEKQIKHLEIEKNAESSKA 772
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
E++ KL + + LEK + L+EK A+A EE V + +++ +T+
Sbjct: 773 SSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETV 832
Query: 243 NELN 246
N+L+
Sbjct: 833 NKLH 836
Score = 57.8 bits (138), Expect = 9e-09
Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 25/230 (10%)
Query: 16 ALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQ 75
ALQ+ E + + L E D ER KA V + + + L + D+ L +
Sbjct: 352 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 411
Query: 76 KLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI 135
+L +AAD + +E +EEK +++++Q + + + D + V+ K I
Sbjct: 412 QLRTMVEAADREK-----VELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRI 466
Query: 136 LEGELERAEERAEVSELK--------CGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
+E E + A EV+EL+ GD++ L + L+ + + EK ++
Sbjct: 467 MELEKDLALRVQEVAELRRRLESNKPAGDVDMSL----SLLQEISSLQEKLEVTRTDHQR 522
Query: 188 EIKLLS------DKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEEN 231
EI L ++ + E +A + KL K + L+ KL A +EN
Sbjct: 523 EITSLKEHFGAREETHQKEIKALYT--ATEKLSKENESLKSKLEHANKEN 570
Score = 53.5 bits (127), Expect = 2e-07
Identities = 58/238 (24%), Positives = 113/238 (47%), Gaps = 35/238 (14%)
Query: 10 VKRKIQALQQQADEAEDRAQGLQRELD-GERERREKAEGDVAALNRRIQLVEEELDRAQE 68
++RK+ L+++ + + ++ Q L+ + E + K E + L + + E++L A+E
Sbjct: 958 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 1017
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEE 128
+ LQ+LEE K AD+++ A E+ M+I E KE E E+
Sbjct: 1018 ENSGLLQELEELRKQADKAK--------AAQTAEDAMQIMEQMTKE----KTETLASLED 1065
Query: 129 VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEE 188
+ L+ EL+ + E LKNV KS E + + ++K +++ +E
Sbjct: 1066 TKQTNAKLQNELDTLK-------------ENNLKNVEELNKSKELLTVE-NQKMEEFRKE 1111
Query: 189 IKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
I+ L + A+ +++ A E+ + L E+L ++++E V HQ L++ + LN
Sbjct: 1112 IETLK------QAAAQKSQQLSALQEENV-KLAEELGRSRDE-VTSHQKLEEERSVLN 1161
Score = 52.4 bits (124), Expect = 4e-07
Identities = 50/238 (21%), Positives = 107/238 (44%), Gaps = 31/238 (13%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
L ++E + + + L + + E+ ++E++ ++ + ++AL + EEL
Sbjct: 1085 LKNVEELNKSKELLTVENQKMEE----FRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1140
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKD--EEKMEIQEMQLKEAKHIAEE 121
R+++ + T+ QKLEE + MK E++ +KD EEK +Q+ + + E
Sbjct: 1141 GRSRDEV-TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK-SISITSALLTE 1198
Query: 122 ADRKYEEVARKLVILEGELERAEERAEVS----------ELKCGDLEEELKNVTNNLKSL 171
D + E++ ++ +L GE A+ V ELK +LE +LK L S
Sbjct: 1199 KDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 1258
Query: 172 EAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
++ ++++++ + E++ +F + L++ DL+ K+ E
Sbjct: 1259 SGNTDTQADEDERAQ-------------ESQIDFLNSVIVDLQRKNQDLKMKVEMMSE 1303
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/283 (22%), Positives = 119/283 (42%), Gaps = 45/283 (15%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGD-------VAALNRRI 56
LN LE KRK++ LQ + +E L+ E+ R + E D VA L RR+
Sbjct: 428 LNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRL 487
Query: 57 QLVEE--ELDRAQERLATALQKLEEAEKAADESERGMKVIENR--AMKDEEKMEIQ---- 108
+ + ++D + L E+ E + +R + ++ A ++ + EI+
Sbjct: 488 ESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYT 547
Query: 109 --EMQLKEAKHIAEEADRKYEEVARKLVILEGELERA--------------------EER 146
E KE + + + + +E + + + + +LE A E
Sbjct: 548 ATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTET 607
Query: 147 AEVSELKCG------DLEEELKNVTNNLKSLEAASEKYSEK-EDKYEEEIKLLSDKLKEA 199
AE +ELK D + E++N+ N S AA K E K + IK + L+
Sbjct: 608 AEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAI 667
Query: 200 ETRAEFAE-RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 241
++ + AE + + ++E T++ L+E + KE V + +QT
Sbjct: 668 RSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQT 710
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 69.3 bits (168), Expect = 3e-12
Identities = 62/278 (22%), Positives = 118/278 (42%), Gaps = 44/278 (15%)
Query: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVA-------ALNRRIQLV 59
LEA +++I+ L+ + + +A + REL G + + +++ L + +Q++
Sbjct: 786 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 845
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIA 119
+E+ A E + + ++E + E ++ + K E + E + +E
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 905
Query: 120 EE---ADRKYEEVARKLVILEGE----LERAEERAEVSELKCGDLEEELKNVTNNL---- 168
E+ A K E +++ + G+ L + + + E +L+ +L N
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 965
Query: 169 KSLE----AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA------------------ 206
KS+E A + E K+EEE K L KL + E + E +
Sbjct: 966 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSET 1025
Query: 207 ----ERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
E + L+KT+ D E+KL A+EEN GL Q L++
Sbjct: 1026 KTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1063
Score = 64.7 bits (156), Expect = 7e-11
Identities = 57/244 (23%), Positives = 111/244 (45%), Gaps = 11/244 (4%)
Query: 3 GLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEE 62
G + E + K Q + + D + + LQ + D ER K ++ AL ++ V +E
Sbjct: 639 GTETAEFAELKTQIEKMRLDYQHE-IENLQNQQDSERAAHAK---EMEALRAKLMKVIKE 694
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
+ + E + + L K E+ E E + ++ +K +E +E+ + + E + +
Sbjct: 695 KENSLEAIRSKLDKAEDQHLV--EMEDTLNKLQEAEIKVKE-LEVLQAKCNEQTKVIDNF 751
Query: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
+ + KL+ L+ L +A + SE+K L ++L+ +K LE S K
Sbjct: 752 TSQLKATEEKLLDLDA-LRKASSEGK-SEMK--KLRQQLEAAEKQIKHLEIEKNAESSKA 807
Query: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTL 242
E++ KL + + LEK + L+EK A+A EE V + +++ +T+
Sbjct: 808 SSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETV 867
Query: 243 NELN 246
N+L+
Sbjct: 868 NKLH 871
Score = 53.5 bits (127), Expect = 2e-07
Identities = 58/238 (24%), Positives = 113/238 (47%), Gaps = 35/238 (14%)
Query: 10 VKRKIQALQQQADEAEDRAQGLQRELD-GERERREKAEGDVAALNRRIQLVEEELDRAQE 68
++RK+ L+++ + + ++ Q L+ + E + K E + L + + E++L A+E
Sbjct: 993 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 1052
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEE 128
+ LQ+LEE K AD+++ A E+ M+I E KE E E+
Sbjct: 1053 ENSGLLQELEELRKQADKAK--------AAQTAEDAMQIMEQMTKE----KTETLASLED 1100
Query: 129 VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEE 188
+ L+ EL+ + E LKNV KS E + + ++K +++ +E
Sbjct: 1101 TKQTNAKLQNELDTLK-------------ENNLKNVEELNKSKELLTVE-NQKMEEFRKE 1146
Query: 189 IKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
I+ L + A+ +++ A E+ + L E+L ++++E V HQ L++ + LN
Sbjct: 1147 IETLK------QAAAQKSQQLSALQEENV-KLAEELGRSRDE-VTSHQKLEEERSVLN 1196
Score = 52.4 bits (124), Expect = 4e-07
Identities = 50/238 (21%), Positives = 107/238 (44%), Gaps = 31/238 (13%)
Query: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
L ++E + + + L + + E+ ++E++ ++ + ++AL + EEL
Sbjct: 1120 LKNVEELNKSKELLTVENQKMEE----FRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1175
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKD--EEKMEIQEMQLKEAKHIAEE 121
R+++ + T+ QKLEE + MK E++ +KD EEK +Q+ + + E
Sbjct: 1176 GRSRDEV-TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK-SISITSALLTE 1233
Query: 122 ADRKYEEVARKLVILEGELERAEERAEVS----------ELKCGDLEEELKNVTNNLKSL 171
D + E++ ++ +L GE A+ V ELK +LE +LK L S
Sbjct: 1234 KDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 1293
Query: 172 EAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
++ ++++++ + E++ +F + L++ DL+ K+ E
Sbjct: 1294 SGNTDTQADEDERAQ-------------ESQIDFLNSVIVDLQRKNQDLKMKVEMMSE 1338
Score = 45.4 bits (106), Expect = 4e-05
Identities = 52/226 (23%), Positives = 97/226 (42%), Gaps = 25/226 (11%)
Query: 2 AGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEE 61
+ L+S+ +V + + + + + R++ G +E AL + Q +E+
Sbjct: 314 SSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTALQE-------ALKEKQQHIEQ 366
Query: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK--EAKHIA 119
L A + LE AE A S G E +D + E++ K + + +
Sbjct: 367 LL---------AERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMV 417
Query: 120 EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 179
E ADR+ E+ +L + ++E + R E + GDLE + K +K LE +
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEK 477
Query: 180 EKEDKYEEEIK-----LLSDKLKEAETRAEFAERT--VAKLEKTID 218
K DK + E++ +S+K + E + A R VA+L + ++
Sbjct: 478 TKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLE 523
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.123 0.304
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,549,849
Number of Sequences: 37866
Number of extensions: 353559
Number of successful extensions: 13213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 730
Number of HSP's successfully gapped in prelim test: 946
Number of HSP's that attempted gapping in prelim test: 3025
Number of HSP's gapped (non-prelim): 5925
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.