Search of human proteins with 4506049

Search of human proteins with 4506049

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506049 hematopoietically expressed homeobox [Homo sapiens]        562   e-160
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   90   2e-18
gi|11386181 H2.0-like homeobox [Homo sapiens]                          87   1e-17
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                  86   3e-17
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    82   6e-16
gi|147901462 brain specific homeobox [Homo sapiens]                    81   8e-16
gi|19923352 NK3 homeobox 1 [Homo sapiens]                              80   1e-15
gi|94536800 empty spiracles homolog 1 [Homo sapiens]                   79   4e-15
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           77   2e-14
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   76   3e-14
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             76   4e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              75   6e-14
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi...    74   1e-13
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               73   2e-13
gi|12056969 homeobox C8 [Homo sapiens]                                 72   5e-13
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       72   7e-13
gi|13273315 homeobox B4 [Homo sapiens]                                 72   7e-13
gi|169636435 caudal type homeobox 2 [Homo sapiens]                     71   1e-12
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        70   1e-12
gi|31377777 NK2 homeobox 8 [Homo sapiens]                              70   1e-12
gi|6633798 BarH-like homeobox 2 [Homo sapiens]                         70   1e-12
gi|148613882 homeobox A4 [Homo sapiens]                                70   3e-12
gi|116174748 developing brain homeobox 2 [Homo sapiens]                70   3e-12
gi|10140847 homeobox A2 [Homo sapiens]                                 69   4e-12
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    69   4e-12
gi|63054872 ladybird homeobox 1 [Homo sapiens]                         69   4e-12
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    69   6e-12
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    68   7e-12
gi|14149611 empty spiracles homeobox 2 [Homo sapiens]                  68   7e-12
gi|89257348 homeo box HB9 [Homo sapiens]                               68   7e-12

>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score =  562 bits (1448), Expect = e-160
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 60
           MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS
Sbjct: 1   MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 60

Query: 61  LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL 120
           LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL
Sbjct: 61  LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL 120

Query: 121 GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 180
           GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ
Sbjct: 121 GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 180

Query: 181 VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP 240
           VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP
Sbjct: 181 VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP 240

Query: 241 ASQEDLESEISEDSDQEVDIEGDKSYFNAG 270
           ASQEDLESEISEDSDQEVDIEGDKSYFNAG
Sbjct: 241 ASQEDLESEISEDSDQEVDIEGDKSYFNAG 270


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 64/176 (36%), Positives = 84/176 (47%), Gaps = 19/176 (10%)

Query: 41  GPAAPTPAPTL-PSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGP 99
           G +   PA +L P P SS        R P + P P+ P      A    A  GP G GG 
Sbjct: 56  GASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPP-----AGGAPAVPGPSGLGGA 110

Query: 100 ------LYPFP----RTVNDYTHALLRHDPL-GKPLLWSPFLQRPLHKRKGGQVRFSNDQ 148
                  +P+     R   D   A L   P  G   +  P+  R   KRK  +  FS  Q
Sbjct: 111 GGLAGLTFPWMDSGRRFAKDRLTAAL--SPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQ 168

Query: 149 TIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNK 204
            +ELE++F  QKYL+  ER  LAK L++++ QVKTWFQNRR KWRR   E  ++ +
Sbjct: 169 VLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAER 224


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 34/270 (12%)

Query: 2   QYPHPGPAAGAVGVPLYAPTPLLQPAH----PTP------FYIEDILGRGPAAPTPAPTL 51
           Q P P P AGA+  P      +  P H    P P      F I+ IL    A   P    
Sbjct: 136 QQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILS---AEFDPKVKE 192

Query: 52  PSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGP----GGFGGPLYPFPRTV 107
            +     TSL++  R     P  +H +    SA    A+  P         PL   PR  
Sbjct: 193 GNTLRDLTSLLTGGR-----PAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPR-- 245

Query: 108 NDYTHALLRHDPLGKPLLWSPFL-QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPE 166
           N   H      P    +L    + Q    KR   +  FSN Q   LEK+FE QKY++ P+
Sbjct: 246 NSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPD 305

Query: 167 RKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEE--------LESLDSSCDQR 218
           RK+LA ML L++ QVK WFQNRR KWR  K+   Q +K +E          + D   D+R
Sbjct: 306 RKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDER 365

Query: 219 QDLPSE-QNKGASLDSSQCSPSPASQEDLE 247
               SE + +  S DS     +P+  E  E
Sbjct: 366 SPSRSEGEAESESSDSESLDMAPSDTERTE 395


>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 74/230 (32%), Positives = 100/230 (43%), Gaps = 27/230 (11%)

Query: 2   QYPHPG-PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 60
           Q PHP  P +  +   L +P     PA   P      LG GP    P  T PS  +SF  
Sbjct: 8   QTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGAS-YLG-GPPGGRPGATYPSLPASFAG 65

Query: 61  LVSPY------------------RTPVYEPTP-IHPAFSHHSAAALAAAYGPGGFGGPLY 101
           L +P+                  R P + P P   P     +  A+ +       GG  +
Sbjct: 66  LGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNF 125

Query: 102 PFP----RTVNDYTHALLRHDPLGKPL-LWSPFLQRPLHKRKGGQVRFSNDQTIELEKKF 156
           P+     R V D   A     P      +  P+  R   KRK  +  FS  Q  ELEK+F
Sbjct: 126 PWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRF 185

Query: 157 ETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKE 206
             QKYL+  ER  LAK L++++ QVKTWFQNRR KWRR   E  ++ +++
Sbjct: 186 HRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQ 235


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 81.6 bits (200), Expect = 6e-16
 Identities = 86/288 (29%), Positives = 119/288 (41%), Gaps = 63/288 (21%)

Query: 8   PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGR-------GPAAPTPAPTLPSPNSSFTS 60
           PA G +   L +P   L  A  TP  I DIL R       G A P+ +P+  S +SS ++
Sbjct: 75  PATGGLS-SLGSPPQQLSAA--TPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSA 131

Query: 61  LVS--------------------------PYRTPVYEPTPIHPAFSHHSAAALAAAYGPG 94
             S                          P  + +  P P    +   SAAA+AA    G
Sbjct: 132 SASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAV---G 188

Query: 95  GFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPL-----HKRKGGQVRFSNDQT 149
            +  PL   P     +   +++  P     L     Q  +      KRK  +  FS  Q 
Sbjct: 189 RYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQI 248

Query: 150 IELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELE 209
             LEK FE  KYL+ PER RLA  L ++E QVK WFQNRR KWR          KK   E
Sbjct: 249 FALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR----------KKHAAE 298

Query: 210 SLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQE 257
              ++  ++QD  +E+ KGAS +  +        +D    +  +SD E
Sbjct: 299 M--ATAKKKQDSETERLKGASENEEE-------DDDYNKPLDPNSDDE 337


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 81.3 bits (199), Expect = 8e-16
 Identities = 67/205 (32%), Positives = 89/205 (43%), Gaps = 55/205 (26%)

Query: 21  TPLLQPA---HPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHP 77
           T  L PA    PT F+IEDIL                              +++P P+  
Sbjct: 6   TSPLHPASSQRPTSFFIEDIL------------------------------LHKPKPLRE 35

Query: 78  AFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLR----HDPL-----GKPLLWSP 128
               H A++LA+      +G PL P P  +  + H  L     H P      G P+    
Sbjct: 36  VAPDHFASSLASRVPLLDYGYPLMPTPTLLAPHAHHPLHKGDHHHPYFLTTSGMPV--PA 93

Query: 129 FLQRPLH--------KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 180
               P H        +R+  +  FS+ Q   LEK+FE Q+YLS PER  LA  L LSE Q
Sbjct: 94  LFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQ 153

Query: 181 VKTWFQNRRAKWR---RLKQENPQS 202
           VKTWFQNRR K +   R  Q+ P++
Sbjct: 154 VKTWFQNRRMKHKKQLRKSQDEPKA 178


>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 80/236 (33%), Positives = 93/236 (39%), Gaps = 40/236 (16%)

Query: 4   PHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVS 63
           P PG A      P     PL      T F I+DIL  G           +      +   
Sbjct: 7   PRPGEAKAEGAAPPTPSKPL------TSFLIQDILRDG-----------AQRQGGRTSSQ 49

Query: 64  PYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDP---L 120
             R P  EP P  P      A A       G         PR   +    L   +P   L
Sbjct: 50  RQRDPEPEPEP-EPEGGRSRAGAQNDQLSTG---------PRAAPEEAETLAETEPERHL 99

Query: 121 GKPLLWS-------PFL-QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAK 172
           G  LL S       P L Q P   +K  +  FS+ Q IELE+KF  QKYLS PER  LAK
Sbjct: 100 GSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAK 159

Query: 173 MLQLSERQVKTWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPSEQN 226
            L+L+E QVK WFQNRR K +R  L  E     K   L +L      R  L S  N
Sbjct: 160 NLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYN 215


>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
          Length = 290

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 72/238 (30%), Positives = 103/238 (43%), Gaps = 22/238 (9%)

Query: 7   GPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYR 66
           G   G  G  L A     +P  PT            A  +  P   +  +  +    P  
Sbjct: 58  GTGGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPEL 117

Query: 67  TPVYEPTPIHPAFSHHSAAALAAA--YGPGGFGG-----PLYPFPRTVND--YTHALLRH 117
             V+     HPA + H A  L A+    P  F G     PL+ +P  + +  + H     
Sbjct: 118 --VFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQAS 175

Query: 118 D-PLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQL 176
           D P    LL  PF ++P   R      FS  Q + LE+ FE   Y+   ERK+LA  L L
Sbjct: 176 DVPQDGLLLHGPFARKPKRIRTA----FSPSQLLRLERAFEKNHYVVGAERKQLAGSLSL 231

Query: 177 SERQVKTWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLD 232
           SE QVK WFQNRR K++R  L++E P+S +K++     S    R  + ++Q  G  +D
Sbjct: 232 SETQVKVWFQNRRTKYKRQKLEEEGPESEQKKK----GSHHINRWRIATKQANGEDID 285


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 58/192 (30%), Positives = 76/192 (39%), Gaps = 29/192 (15%)

Query: 20  PTPLLQPAHPTPFYIEDILGRGPAAPTPAP---TLPSPNSSFTSLVSPYRTPVYEPTPIH 76
           P P    + P   Y    +GR P  P P P    L +        +SPY  P     P  
Sbjct: 24  PAPEFSASPPACLY----MGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAV 79

Query: 77  PAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHK 136
               HH  A LA  + P G      PFP         L   + +  P  W    +    K
Sbjct: 80  AHLHHHLPAQLALPHPPAG------PFPEGAEP--GVLEEPNRVQLPFPWMKSTKAHAWK 131

Query: 137 --------------RKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVK 182
                          K  +  ++  Q +ELEK+F   KY+S P R  LA ML L+ER +K
Sbjct: 132 GQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIK 191

Query: 183 TWFQNRRAKWRR 194
            WFQNRR KW++
Sbjct: 192 IWFQNRRMKWKK 203


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 36/79 (45%), Positives = 51/79 (64%)

Query: 128 PFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQN 187
           P+  R   K+K  +  F+  Q  ELEK+F  QKYL+  ER  LAK L++++ QVKTWFQN
Sbjct: 192 PYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQN 251

Query: 188 RRAKWRRLKQENPQSNKKE 206
           RR KWRR   E  ++ +++
Sbjct: 252 RRTKWRRQTAEEREAERQQ 270


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 37/78 (47%), Positives = 52/78 (66%)

Query: 133 PLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKW 192
           P  K +  +  F+++Q +ELEK+F  +KYLS  ER ++A  L+LSE QVK WFQNRRAKW
Sbjct: 257 PGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKW 316

Query: 193 RRLKQENPQSNKKEELES 210
           +R+K  N  S   E + +
Sbjct: 317 KRIKAGNVSSRSGEPVRN 334


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 36/71 (50%), Positives = 49/71 (69%)

Query: 136 KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRL 195
           K +  +  F+++Q +ELEK+F  +KYLS  ER ++A  L+LSE QVK WFQNRRAKW+R+
Sbjct: 246 KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRV 305

Query: 196 KQENPQSNKKE 206
           K  N  S   E
Sbjct: 306 KAGNANSKTGE 316


>gi|28912912 NK6 transcription factor related, locus 2 [Homo
           sapiens]
          Length = 277

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 71/206 (34%), Positives = 87/206 (42%), Gaps = 36/206 (17%)

Query: 8   PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGR--GPAAPTPAPTLPSPNSSFTSLVSPY 65
           PA G +G  L    PL      TP  I DILGR  G A       LP  N    S    Y
Sbjct: 43  PALGGLGAQL----PL-----GTPHGISDILGRPVGAAGGGLLGGLPRLNG-LASSAGVY 92

Query: 66  RTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLL 125
             P               AAA+A      G+  PL   P     +   +++  P   P L
Sbjct: 93  FGP---------------AAAVAR-----GYPKPLAELPGRPPIFWPGVVQGAPWRDPRL 132

Query: 126 WSPFLQRPL----HKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQV 181
             P     +     K+K  +  FS  Q   LEK FE  KYL+ PER RLA  L ++E QV
Sbjct: 133 AGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV 192

Query: 182 KTWFQNRRAKWRRLKQENPQSNKKEE 207
           K WFQNRR KWR+       S KK++
Sbjct: 193 KVWFQNRRTKWRKRHAAEMASAKKKQ 218


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 62/182 (34%), Positives = 86/182 (47%), Gaps = 29/182 (15%)

Query: 55  NSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHAL 114
           +S  ++ VS  R+P  E   + P  +H SA  L +  G GG  GP             A 
Sbjct: 147 DSEMSASVSGDRSPRTEDDGVGPRGAHVSA--LCSGAGGGGGSGPAGV----------AE 194

Query: 115 LRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKML 174
              +P             P  ++K  +  FS+ Q  ELE++F  Q+YLS PER  LA  L
Sbjct: 195 EEEEPAA-----------PKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASL 243

Query: 175 QLSERQVKTWFQNRRAKWRRLKQ-----ENPQSNKKEELESLDSSCDQRQDLPSEQNKGA 229
           +L+E QVK WFQNRR K +R +       +  + KK  ++ L    DQRQ LP E  +  
Sbjct: 244 KLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRD-DQRQYLPGEVLRPP 302

Query: 230 SL 231
           SL
Sbjct: 303 SL 304


>gi|12056969 homeobox C8 [Homo sapiens]
          Length = 242

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 38/107 (35%), Positives = 64/107 (59%), Gaps = 2/107 (1%)

Query: 123 PLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVK 182
           P L  P+++     R+ G+  +S  QT+ELEK+F    YL+   R  ++  L L+ERQVK
Sbjct: 135 PSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVK 194

Query: 183 TWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPSEQNK 227
            WFQNRR KW++   K + P +  +E++E   +  +++++   E+NK
Sbjct: 195 IWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENK 241


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 74/250 (29%), Positives = 108/250 (43%), Gaps = 46/250 (18%)

Query: 25  QPAHPTPFYIEDILGRGPAAPTPAPTLPS------------------PNSSFTSLVSPYR 66
           +P     F IE+IL   P     AP   +                  P  S  +++   +
Sbjct: 22  RPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQ 81

Query: 67  TPVYEPTPIHP-AFSHHSAAALAAAYG-PGGFGGPLYPFPRTVNDYTHALLRHDPLGKPL 124
             V++  P+ P   S  S+A LAA  G PG  G P  P    +     A    +P  K  
Sbjct: 82  AAVFK-FPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKA- 139

Query: 125 LWSPFLQRPLHKRKGGQVR--FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVK 182
                       +KG + R  F+  Q + LEK+FE QKYLS P+R  LA+ L LS+ QVK
Sbjct: 140 ------------KKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVK 187

Query: 183 TWFQNRRAKWRRL-----KQENPQSNKKEELESLDSSCDQ--RQDLPSEQNKGASLDSSQ 235
           TW+QNRR KW+++       E+P   K    ++   + +Q   Q+   +  K A +    
Sbjct: 188 TWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKDAEKPAEVPG-- 245

Query: 236 CSPSPASQED 245
             PS  S+ED
Sbjct: 246 -EPSDRSRED 254


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 54/178 (30%), Positives = 76/178 (42%), Gaps = 37/178 (20%)

Query: 20  PTPLLQPAHPTPFYIEDILGRGPAAPTPAPT---LPSPNSSFTSLVSPYRTPVYEPTPIH 76
           P P   P  P P       G  P AP P P    LP P     ++ S    P     P+H
Sbjct: 76  PPPPPPPPPPPP-------GLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLH 128

Query: 77  PAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHK 136
           P+ SH +                +YP+ R V+  T  +  +   G+P             
Sbjct: 129 PSPSHSACKEPV-----------VYPWMRKVHVST--VNPNYAGGEP------------- 162

Query: 137 RKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR 194
            K  +  ++  Q +ELEK+F   +YL+   R  +A  L LSERQ+K WFQNRR KW++
Sbjct: 163 -KRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKK 219


>gi|169636435 caudal type homeobox 2 [Homo sapiens]
          Length = 313

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 67/226 (29%), Positives = 98/226 (43%), Gaps = 25/226 (11%)

Query: 2   QYPHPG----PAAGAVGVPL---YAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSP 54
           QYP  G     AA A    L    +P P    A+  P   ED  G  P     A    + 
Sbjct: 36  QYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLR-EDWNGYAPGGAAAAANAVAH 94

Query: 55  --NSSFTSLVSPYRTPV-YEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYT 111
             N    +    Y +P  Y P        HH AAA + A G      P  P P      T
Sbjct: 95  GLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAA----T 150

Query: 112 HALLRHDPLGKPLLWSPFLQRPLHKRKGGQVR----------FSNDQTIELEKKFETQKY 161
            A  +  P G+      ++++P  +  G QV+          +++ Q +ELEK+F   +Y
Sbjct: 151 AAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRY 210

Query: 162 LSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEE 207
           ++   +  LA  L LSERQVK WFQNRRAK R++ ++  Q  ++++
Sbjct: 211 ITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQ 256


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 48/115 (41%), Positives = 59/115 (51%), Gaps = 19/115 (16%)

Query: 92  GPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVR-------- 143
           GPGG     +  P + +D+     R  P G P   SP  +RP   R GG  R        
Sbjct: 99  GPGGLERTPFLSP-SHSDFKEEKERLLPAGSP---SPGSERP---RDGGAERQAGAAKKK 151

Query: 144 ----FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR 194
               FS  Q  +LE  F+ ++YLS  ER  LA  LQL+E QVKTWFQNRR KW+R
Sbjct: 152 TRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR 206


>gi|31377777 NK2 homeobox 8 [Homo sapiens]
          Length = 239

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 37/79 (46%), Positives = 51/79 (64%), Gaps = 4/79 (5%)

Query: 136 KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRL 195
           KRK  +V FS  QT+ELE++F  Q+YLS PER++LA +L+L+  QVK WFQN R K +R 
Sbjct: 83  KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRA 142

Query: 196 K----QENPQSNKKEELES 210
           +     E+P      EL +
Sbjct: 143 RAPGAAESPDLAASAELHA 161


>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
          Length = 279

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 49/141 (34%), Positives = 71/141 (50%), Gaps = 18/141 (12%)

Query: 136 KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRL 195
           K +  +  F+  Q + LEKKF+ QKYLS P+R  LA+ L L++ QVKTW+QNRR KW+++
Sbjct: 132 KPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKM 191

Query: 196 ----KQENPQSNK----------KEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPA 241
                QE P   K           EE+E+ +    Q Q    EQ + +      C     
Sbjct: 192 VLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQG--QEQLEPSQGQEELCEAQEP 249

Query: 242 SQEDLESEISE--DSDQEVDI 260
              D+  E++E  D  QE+ I
Sbjct: 250 KARDVPLEMAEPPDPPQELPI 270


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 60/203 (29%), Positives = 87/203 (42%), Gaps = 36/203 (17%)

Query: 16  PLYAPTPLLQPAHPTPFYIEDILGRGPAAP--TPAPTLPSPNSS-------FTSLVSPYR 66
           P Y P   L PAH           RG A+P   P P  P   +         + ++ P  
Sbjct: 82  PAY-PAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQL 140

Query: 67  TPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLG----K 122
            P  +P  + PA      AA A    P G   P  P           L    PLG    +
Sbjct: 141 PPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPL---------LLADKSPLGLKGKE 191

Query: 123 PLLWSPFLQRPLH-----------KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLA 171
           P+++ P++++ +H           + K  +  ++  Q +ELEK+F   +YL+   R  +A
Sbjct: 192 PVVY-PWMKK-IHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIA 249

Query: 172 KMLQLSERQVKTWFQNRRAKWRR 194
             L LSERQVK WFQNRR KW++
Sbjct: 250 HTLCLSERQVKIWFQNRRMKWKK 272


>gi|116174748 developing brain homeobox 2 [Homo sapiens]
          Length = 339

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 34/61 (55%), Positives = 41/61 (67%)

Query: 144 FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSN 203
           FS DQ   LEK F+ QKY+S  +RK+LA  L L E QVK WFQNRR KWR  K++   SN
Sbjct: 193 FSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSN 252

Query: 204 K 204
           +
Sbjct: 253 R 253


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 34/77 (44%), Positives = 47/77 (61%)

Query: 144 FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSN 203
           ++N Q +ELEK+F   KYL  P R  +A +L L+ERQVK WFQNRR K +R  Q     N
Sbjct: 150 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQN 209

Query: 204 KKEELESLDSSCDQRQD 220
            + + +SL+ S    +D
Sbjct: 210 SEGKCKSLEDSEKVEED 226


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 34/69 (49%), Positives = 49/69 (71%), Gaps = 1/69 (1%)

Query: 131 QRP-LHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRR 189
           +RP   +R+  +V FS  Q  ELE++F+ Q+YLS PER +LA +L+L+  QVK WFQNRR
Sbjct: 131 ERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRR 190

Query: 190 AKWRRLKQE 198
            K +R +Q+
Sbjct: 191 YKCKRQRQD 199


>gi|63054872 ladybird homeobox 1 [Homo sapiens]
          Length = 281

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 53/160 (33%), Positives = 78/160 (48%), Gaps = 37/160 (23%)

Query: 136 KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRL 195
           KR+  +  F+N Q  ELEK+F  QKYLSP +R ++A+ L L+  QV TWFQNRRAK +R 
Sbjct: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD 183

Query: 196 KQE---NPQSNKK------------EELESLDSS-------CDQRQD------LPSEQNK 227
            +E   + +S KK             ELE    +       C + +       LP    K
Sbjct: 184 LEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPK 243

Query: 228 GASLDSSQCSPS------PASQEDLESEISEDSDQEVDIE 261
                + Q SP+      PAS +D      ++ D+E+D++
Sbjct: 244 APGAGALQLSPASPLTDQPASSQDCS---EDEEDEEIDVD 280


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 68.6 bits (166), Expect = 6e-12
 Identities = 33/68 (48%), Positives = 46/68 (67%)

Query: 131 QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRA 190
           Q    +R+  +V FS  Q + LE++F+ Q+YLS PER+ LA  LQL+  QVK WFQNRR 
Sbjct: 44  QPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRY 103

Query: 191 KWRRLKQE 198
           K +R +Q+
Sbjct: 104 KCKRQRQD 111



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 21/88 (23%)

Query: 22  PLLQPAHPTPFYIED---ILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHPA 78
           PL       P  + D    LG GP AP      PSP   +++ VSPY             
Sbjct: 120 PLTPRRVAVPVLVRDGKPCLGPGPGAPA----FPSP---YSAAVSPY-----------SC 161

Query: 79  FSHHSAAALAAAYGPGGFGGPLYPFPRT 106
           +  +S A   A YG    G P  P P T
Sbjct: 162 YGGYSGAPYGAGYGTCYAGAPSGPAPHT 189


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 34/67 (50%), Positives = 47/67 (70%), Gaps = 1/67 (1%)

Query: 132 RPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAK 191
           +P  +RK  +V FS  Q  ELE++F+ Q+YLS PER+ LA  L+L+  QVK WFQNRR K
Sbjct: 144 KPRSRRKP-RVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYK 202

Query: 192 WRRLKQE 198
            +R +Q+
Sbjct: 203 CKRQRQD 209


>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
          Length = 252

 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 54/164 (32%), Positives = 77/164 (46%), Gaps = 14/164 (8%)

Query: 53  SPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAA--LAAAYGPGGFGG-----PLYPFPR 105
           +P+  F   VS    P     P+HP    H+ AA  L +++ P          P   +P 
Sbjct: 66  NPDLVFAEAVSHPPNPA---VPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPW 122

Query: 106 TVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVR--FSNDQTIELEKKFETQKYLS 163
            ++ Y +  L H   G       FL      RK  ++R  FS  Q + LE  FE   Y+ 
Sbjct: 123 LIHRYRY--LGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVV 180

Query: 164 PPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEE 207
             ERK+LA  L L+E QVK WFQNRR K++R K E   S+ +++
Sbjct: 181 GAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQK 224


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 33/74 (44%), Positives = 48/74 (64%)

Query: 134 LHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWR 193
           L K +  +  F++ Q +ELE +F+  KYLS P+R  +A  L L+E QVK WFQNRR KW+
Sbjct: 238 LGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWK 297

Query: 194 RLKQENPQSNKKEE 207
           R K+   Q+ ++ E
Sbjct: 298 RSKKAKEQAAQEAE 311


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,050,061
Number of Sequences: 37866
Number of extensions: 900827
Number of successful extensions: 5934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 339
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 4640
Number of HSP's gapped (non-prelim): 1567
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.