Search of human proteins with 4502403

Search of human proteins with 4502403

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502403 biglycan preproprotein [Homo sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502403 biglycan preproprotein [Homo sapiens]                      756   0.0  
gi|41350214 asporin [Homo sapiens]                                    398   e-111
gi|19743846 decorin isoform a preproprotein [Homo sapiens]            397   e-111
gi|4503271 decorin isoform a preproprotein [Homo sapiens]             397   e-111
gi|19743848 decorin isoform b precursor [Homo sapiens]                217   1e-56
gi|19743850 decorin isoform c precursor [Homo sapiens]                175   5e-44
gi|41349454 proline arginine-rich end leucine-rich repeat protei...   136   3e-32
gi|4506041 proline arginine-rich end leucine-rich repeat protein...   136   3e-32
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]    131   1e-30
gi|4505047 lumican precursor [Homo sapiens]                           128   7e-30
gi|45505137 podocan [Homo sapiens]                                    124   1e-28
gi|19743852 decorin isoform d precursor [Homo sapiens]                121   9e-28
gi|5901992 keratocan [Homo sapiens]                                   119   4e-27
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...   118   1e-26
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                  117   2e-26
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                  117   2e-26
gi|71040111 fibromodulin precursor [Homo sapiens]                     113   2e-25
gi|153251229 chondroadherin precursor [Homo sapiens]                  113   2e-25
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                  111   1e-24
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...   109   4e-24
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...   109   4e-24
gi|157694513 leucine-rich repeat-containing G protein-coupled re...   106   3e-23
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...   106   3e-23
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...   106   3e-23
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom...   104   1e-22
gi|51317373 netrin-G1 ligand [Homo sapiens]                           103   2e-22
gi|122937309 leucine rich repeat containing 4B [Homo sapiens]         103   2e-22
gi|4759146 slit homolog 2 [Homo sapiens]                              102   5e-22
gi|198041768 synleurin [Homo sapiens]                                 102   7e-22
gi|4826876 osteomodulin [Homo sapiens]                                102   7e-22

>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score =  756 bits (1951), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS 60
           MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS
Sbjct: 1   MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS 60

Query: 61  AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 120
           AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV
Sbjct: 61  AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 120

Query: 121 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS 180
           LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS
Sbjct: 121 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS 180

Query: 181 GLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK 240
           GLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK
Sbjct: 181 GLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK 240

Query: 241 IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLK 300
           IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLK
Sbjct: 241 IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLK 300

Query: 301 LLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLA 360
           LLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLA
Sbjct: 301 LLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLA 360

Query: 361 IQFGNYKK 368
           IQFGNYKK
Sbjct: 361 IQFGNYKK 368


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score =  398 bits (1023), Expect = e-111
 Identities = 183/305 (60%), Positives = 241/305 (79%)

Query: 62  MCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121
           MCPFGC C+ RVV CSDLGL SVP  I  DT +LDLQNN I E++++DFKGL  LY L+L
Sbjct: 74  MCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLIL 133

Query: 122 VNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG 181
            NNK++KIH KAF   +KL++LY+S N L EIP NLP SL ELRIH+N+++K+ K  F G
Sbjct: 134 NNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKG 193

Query: 182 LRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKI 241
           +  ++ +EM  NPL+N+G EPGAF+G+ + ++RI+EAKLT +PK LP TL ELHLD+NKI
Sbjct: 194 MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKI 253

Query: 242 QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKL 301
             +ELED  RY +L RLGLG+N+I  IENGSL+ +P +RE+HL+NNKL ++PSGLP+LK 
Sbjct: 254 STVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKY 313

Query: 302 LQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAI 361
           LQ+++LHSN+I +VGVNDFCP    +K++ Y+ ISLFNNPV YWE+QPATFRCV  R+++
Sbjct: 314 LQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSV 373

Query: 362 QFGNY 366
           Q GN+
Sbjct: 374 QLGNF 378


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  397 bits (1020), Expect = e-111
 Identities = 202/362 (55%), Positives = 257/362 (70%), Gaps = 10/362 (2%)

Query: 7   LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
           L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7   LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57

Query: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
           C CHLRVVQCSDLGL  VPK++ PDTTLLDLQNN I+E++  DFK L++L+AL+LVNNKI
Sbjct: 58  CQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI 117

Query: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 186
           SK+   AF+PL KL++LY+SKN L E+P  +P +L ELR H+N I KV K  F+GL  M 
Sbjct: 118 SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMI 177

Query: 187 CIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIE 245
            IE+G NPL++SG E GAF G+ KL+Y+RI++  +T IP+ LP +L ELHLD NKI  ++
Sbjct: 178 VIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVD 237

Query: 246 LEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVV 305
              L   + L +LGL  N I  ++NGSL+  P LRELHLDNNKL RVP GL + K +QVV
Sbjct: 238 AASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVV 297

Query: 306 YLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGN 365
           YLH+NNI+ VG +DFCP G   K+A Y+G+SLF+NPV YWE+QP+TFRCV  R AIQ GN
Sbjct: 298 YLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 357

Query: 366 YK 367
           YK
Sbjct: 358 YK 359


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  397 bits (1020), Expect = e-111
 Identities = 202/362 (55%), Positives = 257/362 (70%), Gaps = 10/362 (2%)

Query: 7   LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
           L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7   LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57

Query: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
           C CHLRVVQCSDLGL  VPK++ PDTTLLDLQNN I+E++  DFK L++L+AL+LVNNKI
Sbjct: 58  CQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI 117

Query: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 186
           SK+   AF+PL KL++LY+SKN L E+P  +P +L ELR H+N I KV K  F+GL  M 
Sbjct: 118 SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMI 177

Query: 187 CIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIE 245
            IE+G NPL++SG E GAF G+ KL+Y+RI++  +T IP+ LP +L ELHLD NKI  ++
Sbjct: 178 VIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVD 237

Query: 246 LEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVV 305
              L   + L +LGL  N I  ++NGSL+  P LRELHLDNNKL RVP GL + K +QVV
Sbjct: 238 AASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVV 297

Query: 306 YLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGN 365
           YLH+NNI+ VG +DFCP G   K+A Y+G+SLF+NPV YWE+QP+TFRCV  R AIQ GN
Sbjct: 298 YLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 357

Query: 366 YK 367
           YK
Sbjct: 358 YK 359


>gi|19743848 decorin isoform b precursor [Homo sapiens]
          Length = 250

 Score =  217 bits (553), Expect = 1e-56
 Identities = 107/189 (56%), Positives = 138/189 (73%), Gaps = 3/189 (1%)

Query: 182 LRNMNC--IEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDH 238
           LR + C  +E+G NPL++SG E GAF G+K L+Y+RI++  +T IP+ LP +L ELHLD 
Sbjct: 62  LRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDG 121

Query: 239 NKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPD 298
           NKI  ++   L   + L +LGL  N I  ++NGSL+  P LRELHLDNNKL RVP GL +
Sbjct: 122 NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAE 181

Query: 299 LKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDR 358
            K +QVVYLH+NNI+ VG +DFCP G   K+A Y+G+SLF+NPV YWE+QP+TFRCV  R
Sbjct: 182 HKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVR 241

Query: 359 LAIQFGNYK 367
            AIQ GNYK
Sbjct: 242 SAIQLGNYK 250



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 71/238 (29%), Positives = 104/238 (43%), Gaps = 48/238 (20%)

Query: 7   LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
           L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7   LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57

Query: 67  CHCHLRVVQCSDL------------------GLK-------------SVPKEISPDTTLL 95
           C CHLRVVQCSDL                  G+K             S+P+ + P  T L
Sbjct: 58  CQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTEL 117

Query: 96  DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPP 155
            L  N IS +     KGL +L  L L  N IS +   + +    L++L++  N L  +P 
Sbjct: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177

Query: 156 NLPSS--LVELRIHDNRIRKV------PKGVFSGLRNMNCIEMGGNPLENSGFEPGAF 205
            L     +  + +H+N I  V      P G  +   + + + +  NP++    +P  F
Sbjct: 178 GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTF 235


>gi|19743850 decorin isoform c precursor [Homo sapiens]
          Length = 212

 Score =  175 bits (444), Expect = 5e-44
 Identities = 84/141 (59%), Positives = 103/141 (73%)

Query: 227 LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDN 286
           LP +L ELHLD NKI  ++   L   + L +LGL  N I  ++NGSL+  P LRELHLDN
Sbjct: 72  LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131

Query: 287 NKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWE 346
           NKL RVP GL + K +QVVYLH+NNI+ VG +DFCP G   K+A Y+G+SLF+NPV YWE
Sbjct: 132 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWE 191

Query: 347 VQPATFRCVTDRLAIQFGNYK 367
           +QP+TFRCV  R AIQ GNYK
Sbjct: 192 IQPSTFRCVYVRSAIQLGNYK 212



 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 69/207 (33%), Positives = 98/207 (47%), Gaps = 24/207 (11%)

Query: 7   LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
           L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7   LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57

Query: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
           C CHLRVVQCSDLGL        P  T L L  N IS +     KGL +L  L L  N I
Sbjct: 58  CQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI 110

Query: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS--LVELRIHDNRIRKV------PKGV 178
           S +   + +    L++L++  N L  +P  L     +  + +H+N I  V      P G 
Sbjct: 111 SAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGH 170

Query: 179 FSGLRNMNCIEMGGNPLENSGFEPGAF 205
            +   + + + +  NP++    +P  F
Sbjct: 171 NTKKASYSGVSLFSNPVQYWEIQPSTF 197


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  136 bits (343), Expect = 3e-32
 Identities = 97/295 (32%), Positives = 149/295 (50%), Gaps = 13/295 (4%)

Query: 34  FMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISP 90
           F   DE A   D    L P    P+    CP  C+C       + C    L+ VP  I P
Sbjct: 46  FPQPDEPAEPTDLPPPLPPGP--PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPP 102

Query: 91  DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHL 150
               L LQNN I+EL  + F+    L  + L NN+I KI ++    L  L  LY+ KN L
Sbjct: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162

Query: 151 VEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK- 209
            E+P  LP +L +LR+  N I ++P GVFS L N+  +++  N L +  F+P  F GLK 
Sbjct: 163 EEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222

Query: 210 LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI--RM 267
           L  L ++   L  +P  +P  +++L+LD NKI+ I       +  L  + L +N++  R 
Sbjct: 223 LMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRG 282

Query: 268 IENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCP 322
           +   S + +  L  LHL +N+++ VP+       L+ +YL++N+I K+     CP
Sbjct: 283 LPKNSFN-ISNLLVLHLSHNRISSVPA---INNRLEHLYLNNNSIEKINGTQICP 333


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  136 bits (343), Expect = 3e-32
 Identities = 97/295 (32%), Positives = 149/295 (50%), Gaps = 13/295 (4%)

Query: 34  FMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISP 90
           F   DE A   D    L P    P+    CP  C+C       + C    L+ VP  I P
Sbjct: 46  FPQPDEPAEPTDLPPPLPPGP--PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPP 102

Query: 91  DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHL 150
               L LQNN I+EL  + F+    L  + L NN+I KI ++    L  L  LY+ KN L
Sbjct: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162

Query: 151 VEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK- 209
            E+P  LP +L +LR+  N I ++P GVFS L N+  +++  N L +  F+P  F GLK 
Sbjct: 163 EEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222

Query: 210 LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI--RM 267
           L  L ++   L  +P  +P  +++L+LD NKI+ I       +  L  + L +N++  R 
Sbjct: 223 LMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRG 282

Query: 268 IENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCP 322
           +   S + +  L  LHL +N+++ VP+       L+ +YL++N+I K+     CP
Sbjct: 283 LPKNSFN-ISNLLVLHLSHNRISSVPA---INNRLEHLYLNNNSIEKINGTQICP 333


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score =  131 bits (329), Expect = 1e-30
 Identities = 94/285 (32%), Positives = 146/285 (51%), Gaps = 7/285 (2%)

Query: 52  PDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFK 111
           P    P  +   P GC    R + C +  L  +P   +P  T L+L  N I+ +  + F 
Sbjct: 305 PLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFN 364

Query: 112 GLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDN 169
           GL +L  L L  N I  S I  KAF  L+KL +L +  N+L++IP  LPS+L EL++++N
Sbjct: 365 GLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNEN 424

Query: 170 RIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP 228
            ++ + +   S L  +  +E+ GN L  +   P AF  LK L YLR+ + K   IP+ LP
Sbjct: 425 NLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLP 484

Query: 229 ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFL--PTLRELHLDN 286
            ++ EL+L++N+I+ I         K+  + L +N+I       L+++    L  + L  
Sbjct: 485 GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSY 544

Query: 287 NKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAY 331
           NKL  VPS LP   LL +V L  N I ++    F  M  G++  Y
Sbjct: 545 NKLYHVPSYLPK-SLLHLVLL-GNQIERIPGYVFGHMEPGLEYLY 587


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score =  128 bits (322), Expect = 7e-30
 Identities = 101/311 (32%), Positives = 157/311 (50%), Gaps = 14/311 (4%)

Query: 52  PDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKD 108
           P S+    S  C   C+C   +   + C +L LKSVP  + P    L L+NN I  + + 
Sbjct: 26  PLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEK 84

Query: 109 DFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRI 166
            F+ +  L  L+L +N +  SKI  + FS L++L+KL+I+ N+L E    LP SL +L++
Sbjct: 85  AFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQL 144

Query: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK 225
             N+I K+  G F GL N+  I +  N L+       AF GLK L YL +S  ++  +P 
Sbjct: 145 THNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPS 201

Query: 226 DLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHL 284
            LP +L  L+LD+NKI  I  E   R++ L  L L HN++        SF + +L EL L
Sbjct: 202 GLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDL 261

Query: 285 DNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPY 344
             NKL  +P+   +   L+  YL  N + K  +  FC +   +  +    + L  N +  
Sbjct: 262 SYNKLKNIPTVNEN---LENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISE 318

Query: 345 WEVQPATFRCV 355
             + P  + C+
Sbjct: 319 TSLPPDMYECL 329


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score =  124 bits (311), Expect = 1e-28
 Identities = 95/322 (29%), Positives = 154/322 (47%), Gaps = 35/322 (10%)

Query: 49  VLDPDSVTPTYSAM-CPFGCHCHLR-VVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR 106
           VL P+   P  +A+ CP  C C    VV C  + L+  P ++   T  L LQNN + ++ 
Sbjct: 101 VLSPEEPGPGPAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIY 160

Query: 107 KDDFKGLQHLYALVLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVEL 164
            ++   L  L  L L NN+++   + EKAF  L  L  LY++ N L   P  LP++L+ +
Sbjct: 161 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISV 220

Query: 165 RIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG-LKLNYLRISEAKLTGI 223
               N + K+    F    N+  + +  N L ++G     F+G   +  L +S   L  +
Sbjct: 221 DFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHV 280

Query: 224 PKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRE 281
           PK LP  L +LHL +NK++ I        S L  L L +N +    ++N +   L +L  
Sbjct: 281 PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEY 340

Query: 282 LHLDNNKLARVPSGLP----------------------DLKLLQVVYLHSNNITKVGVND 319
           L L +N L+RVP+GLP                       ++ L+ + LHSN + + G++ 
Sbjct: 341 LDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIH- 399

Query: 320 FCPMGF-GVKRAYYNGISLFNN 340
             P+ F G+KR +   + L+NN
Sbjct: 400 --PLAFQGLKRLH--TVHLYNN 417



 Score =  108 bits (270), Expect = 8e-24
 Identities = 76/238 (31%), Positives = 113/238 (47%), Gaps = 5/238 (2%)

Query: 65  FGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNN 124
           F    ++ V+  S   L+ VPK + P    L L+NN + ++    F  L  L  L L NN
Sbjct: 261 FNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNN 320

Query: 125 KISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGL 182
            ++   +  + F  L  L+ L +S N+L  +P  LP SLV L +  N IR V   V + +
Sbjct: 321 YLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPI 380

Query: 183 RNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHNKI 241
           R++  + +  N L   G  P AF GLK L+ + +    L  +P  LP  +  L + HN+I
Sbjct: 381 RSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQI 440

Query: 242 QAIELEDLLRYSKLYRLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLARVPSGLP 297
             I  ED      L  L L +N+I    +   +   L  LR L L  N+L  +P GLP
Sbjct: 441 TGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP 498



 Score =  105 bits (262), Expect = 6e-23
 Identities = 74/236 (31%), Positives = 123/236 (52%), Gaps = 7/236 (2%)

Query: 95  LDLQNNDISELRKDDFKGLQHLYALVLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVE 152
           +D   N ++++    F    +L ++ L NNK++   + +  F+    ++ L +S N L  
Sbjct: 220 VDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRH 279

Query: 153 IPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL-KLN 211
           +P +LP +L +L + +N++ K+P G FS L ++  + +  N L + G +   F  L  L 
Sbjct: 280 VPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLE 339

Query: 212 YLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENG 271
           YL +S   L+ +P  LP +L  LHL+ N I++++   L     L  L L  NQ+R     
Sbjct: 340 YLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIH 399

Query: 272 SLSF--LPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGF 325
            L+F  L  L  +HL NN L RVPSGLP  + ++ + +  N IT +G  DF    F
Sbjct: 400 PLAFQGLKRLHTVHLYNNALERVPSGLP--RRVRTLMILHNQITGIGREDFATTYF 453



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 70/246 (28%), Positives = 111/246 (45%), Gaps = 30/246 (12%)

Query: 71  LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--K 128
           L  V   +  L+ VP  +      L + +N I+ + ++DF     L  L L  N+I+  +
Sbjct: 409 LHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQ 468

Query: 129 IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCI 188
           +H  AF  LR L+ L +S N L  +PP LP ++  L++  N +  + +G   G+  +  +
Sbjct: 469 VHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLREL 528

Query: 189 EMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE 247
            +  N L +    P A+ D   L  L I+  +LT IP+ LPE+L  L+L +NKI A+   
Sbjct: 529 YLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPA- 587

Query: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLA---RVPSGLPDLKLLQV 304
                                   +    P L+ + L  NKLA    V S    LK LQV
Sbjct: 588 -----------------------NAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 624

Query: 305 VYLHSN 310
           + +  N
Sbjct: 625 LDIEGN 630



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 70  HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNK--IS 127
           HL+++  +   L  +P+ +      L LQNN IS +  + F    +L  + L  NK  + 
Sbjct: 550 HLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVG 609

Query: 128 KIHEKAFSPLRKLQKLYISKN 148
            + + AF  L+ LQ L I  N
Sbjct: 610 SVVDSAFRRLKHLQVLDIEGN 630


>gi|19743852 decorin isoform d precursor [Homo sapiens]
          Length = 172

 Score =  121 bits (304), Expect = 9e-28
 Identities = 65/130 (50%), Positives = 82/130 (63%), Gaps = 9/130 (6%)

Query: 7   LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
           L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7   LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57

Query: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
           C CHLRVVQCSDLGL  VPK++ PDTTLLDLQNN I+E++  DFK L++L+ + L NN I
Sbjct: 58  CQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHVVYLHNNNI 117

Query: 127 SKIHEKAFSP 136
           S +    F P
Sbjct: 118 SVVGSSDFCP 127



 Score =  110 bits (276), Expect = 2e-24
 Identities = 53/92 (57%), Positives = 65/92 (70%), Gaps = 1/92 (1%)

Query: 277 PTLRELHLDNNKLARVPSG-LPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGI 335
           P    L L NNK+  +  G   +LK L VVYLH+NNI+ VG +DFCP G   K+A Y+G+
Sbjct: 81  PDTTLLDLQNNKITEIKDGDFKNLKNLHVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 140

Query: 336 SLFNNPVPYWEVQPATFRCVTDRLAIQFGNYK 367
           SLF+NPV YWE+QP+TFRCV  R AIQ GNYK
Sbjct: 141 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 172



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 3/70 (4%)

Query: 150 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLE---NSGFEPGAFD 206
           L ++P +LP     L + +N+I ++  G F  L+N++ + +  N +    +S F P   +
Sbjct: 72  LDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHVVYLHNNNISVVGSSDFCPPGHN 131

Query: 207 GLKLNYLRIS 216
             K +Y  +S
Sbjct: 132 TKKASYSGVS 141


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score =  119 bits (298), Expect = 4e-27
 Identities = 86/267 (32%), Positives = 134/267 (50%), Gaps = 11/267 (4%)

Query: 63  CPFGCHC---HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
           CP  C C       + C + GLK +P  I      L LQNN I  + +  F+    L  +
Sbjct: 42  CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100

Query: 120 VLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKG 177
            L  NKI+   I + A S L+KL  L++  N L E+P  LP SL +L++  N++ ++P+G
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160

Query: 178 VFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHL 236
            FS L N+  +++  N L ++ F+   F GLK L  L +++  L  +P  LP    +L L
Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220

Query: 237 DHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNKLARVPSG 295
           D+N I+ I         K+  L L HN++      S  F + ++ +L L +N+L +VP  
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280

Query: 296 LPDLKLLQVVYLHSNNITKVGVNDFCP 322
                 LQ ++L  N I  V V+  CP
Sbjct: 281 SAH---LQHLHLDHNKIKSVNVSVICP 304


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score =  118 bits (295), Expect = 1e-26
 Identities = 88/268 (32%), Positives = 122/268 (45%), Gaps = 29/268 (10%)

Query: 60  SAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR-KDDFKGLQHLYA 118
           S  CP  C C    + C+D GL S+P +I  D T L LQNN I+      D K       
Sbjct: 51  STTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLK------- 103

Query: 119 LVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGV 178
                   +K++         +Q +Y+ +N L E P NLP SL EL + DN +R + +  
Sbjct: 104 --------TKVN---------VQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDS 146

Query: 179 FSGLRNMNCIEMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLD 237
            + +  +  + +  N +     E  AF D  +L  L +S   L+ IP  LP TL EL LD
Sbjct: 147 LARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLD 206

Query: 238 HNKIQAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSG 295
            N+I  I L      + L RL L  N +  + I + + S L  L EL L  N LA  P  
Sbjct: 207 DNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLN 266

Query: 296 LPDLKLLQVVYLHSNNITKVGVNDFCPM 323
           LP    LQ +YL  N I+ +  N    M
Sbjct: 267 LPSAH-LQKLYLQDNAISHIPYNTLAKM 293



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 5/162 (3%)

Query: 50  LDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDD 109
           LD +SV+        F     L+++  S   L S+P  +      L L +N IS +    
Sbjct: 158 LDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHA 217

Query: 110 FKGLQHLYALVLVNNKIS--KIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS-LVELRI 166
           FKGL  L  LVL  N ++  +I +  FS L+ L +L + +N L   P NLPS+ L +L +
Sbjct: 218 FKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYL 277

Query: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL 208
            DN I  +P    + +R +  +++  N L  +    G FD L
Sbjct: 278 QDNAISHIPYNTLAKMRELERLDLSNNNL--TTLPRGLFDDL 317


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score =  117 bits (293), Expect = 2e-26
 Identities = 85/259 (32%), Positives = 130/259 (50%), Gaps = 8/259 (3%)

Query: 63  CPFGCHC-HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121
           CP  C C  +  V C  L L+  P  I+     L LQNN + EL  ++   L  L  L L
Sbjct: 44  CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103

Query: 122 VNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVF 179
            NN IS   + ++AF  L +LQ L ++ N L   P  LP SL    +  N++ ++    F
Sbjct: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTF 163

Query: 180 SGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDH 238
                +  + +  N L N+G  P AF G + +  L +S  +L+ +P  LP +L  LHL +
Sbjct: 164 GEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQN 223

Query: 239 NKIQAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSGL 296
           N I  +    L R ++L  L L HNQ+    ++  + S L +L  L L +N+L  VP+GL
Sbjct: 224 NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 283

Query: 297 PDLKLLQVVYLHSNNITKV 315
           P  + L +++L  N I +V
Sbjct: 284 P--RTLAILHLGRNRIRQV 300



 Score =  107 bits (268), Expect = 1e-23
 Identities = 81/244 (33%), Positives = 118/244 (48%), Gaps = 7/244 (2%)

Query: 81  LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISK--IHEKAFSPLR 138
           L   P+ +     + DL  N + E+    F     L ++ L NN++S   +   AF    
Sbjct: 134 LSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSE 193

Query: 139 KLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENS 198
            +  L +S N L  +PP+LP SL  L + +N I KVP+G  S    +  + +  N L +S
Sbjct: 194 AIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDS 253

Query: 199 GFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYR 257
           G +   F  L  L YL +S  +LT +P  LP TL  LHL  N+I+ +E   L     L  
Sbjct: 254 GLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRY 313

Query: 258 LGLGHNQIRM--IENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKV 315
           L L HNQ+    +  G+L  L  L  LHL  N L RVP  LP  + L+ + L  N++  +
Sbjct: 314 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP--RRLRALVLPHNHVAAL 371

Query: 316 GVND 319
           G  D
Sbjct: 372 GARD 375



 Score =  100 bits (249), Expect = 2e-21
 Identities = 76/240 (31%), Positives = 115/240 (47%), Gaps = 6/240 (2%)

Query: 71  LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI--SK 128
           +  +  S+  L  +P  + P    L LQNN IS++ +        L  L L +N++  S 
Sbjct: 195 IATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 254

Query: 129 IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCI 188
           +    FS L  L+ L +S N L  +P  LP +L  L +  NRIR+V      G R +  +
Sbjct: 255 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYL 314

Query: 189 EMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE 247
            +  N L +SG   GA   L+ L+ L +    L  +P  LP  L  L L HN + A+   
Sbjct: 315 LLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGAR 374

Query: 248 DLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSGLP-DLKLLQV 304
           DL+    L  L L +N++    + + +   L  LR L L  N+L R+P GLP  L+ LQ+
Sbjct: 375 DLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQL 434



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 80  GLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPL 137
           GL  VP  +      L L +N ++ L   D      L  L L  N+++  ++H +AF  L
Sbjct: 346 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 405

Query: 138 RKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLEN 197
           R L+ L ++ N L  +P  LP+ L  L++  N++R +     +GL  +  + +  N L  
Sbjct: 406 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 465

Query: 198 SGFEPGAFDGLKLNYLR 214
               PG +  L+   +R
Sbjct: 466 GDIGPGTWHELQALQVR 482


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score =  117 bits (293), Expect = 2e-26
 Identities = 85/259 (32%), Positives = 130/259 (50%), Gaps = 8/259 (3%)

Query: 63  CPFGCHC-HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121
           CP  C C  +  V C  L L+  P  I+     L LQNN + EL  ++   L  L  L L
Sbjct: 46  CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 105

Query: 122 VNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVF 179
            NN IS   + ++AF  L +LQ L ++ N L   P  LP SL    +  N++ ++    F
Sbjct: 106 HNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTF 165

Query: 180 SGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDH 238
                +  + +  N L N+G  P AF G + +  L +S  +L+ +P  LP +L  LHL +
Sbjct: 166 GEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQN 225

Query: 239 NKIQAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSGL 296
           N I  +    L R ++L  L L HNQ+    ++  + S L +L  L L +N+L  VP+GL
Sbjct: 226 NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 285

Query: 297 PDLKLLQVVYLHSNNITKV 315
           P  + L +++L  N I +V
Sbjct: 286 P--RTLAILHLGRNRIRQV 302



 Score =  107 bits (268), Expect = 1e-23
 Identities = 81/244 (33%), Positives = 118/244 (48%), Gaps = 7/244 (2%)

Query: 81  LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISK--IHEKAFSPLR 138
           L   P+ +     + DL  N + E+    F     L ++ L NN++S   +   AF    
Sbjct: 136 LSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSE 195

Query: 139 KLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENS 198
            +  L +S N L  +PP+LP SL  L + +N I KVP+G  S    +  + +  N L +S
Sbjct: 196 AIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDS 255

Query: 199 GFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYR 257
           G +   F  L  L YL +S  +LT +P  LP TL  LHL  N+I+ +E   L     L  
Sbjct: 256 GLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRY 315

Query: 258 LGLGHNQIRM--IENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKV 315
           L L HNQ+    +  G+L  L  L  LHL  N L RVP  LP  + L+ + L  N++  +
Sbjct: 316 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP--RRLRALVLPHNHVAAL 373

Query: 316 GVND 319
           G  D
Sbjct: 374 GARD 377



 Score =  100 bits (249), Expect = 2e-21
 Identities = 76/240 (31%), Positives = 115/240 (47%), Gaps = 6/240 (2%)

Query: 71  LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI--SK 128
           +  +  S+  L  +P  + P    L LQNN IS++ +        L  L L +N++  S 
Sbjct: 197 IATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256

Query: 129 IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCI 188
           +    FS L  L+ L +S N L  +P  LP +L  L +  NRIR+V      G R +  +
Sbjct: 257 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYL 316

Query: 189 EMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE 247
            +  N L +SG   GA   L+ L+ L +    L  +P  LP  L  L L HN + A+   
Sbjct: 317 LLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGAR 376

Query: 248 DLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSGLP-DLKLLQV 304
           DL+    L  L L +N++    + + +   L  LR L L  N+L R+P GLP  L+ LQ+
Sbjct: 377 DLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQL 436



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 80  GLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPL 137
           GL  VP  +      L L +N ++ L   D      L  L L  N+++  ++H +AF  L
Sbjct: 348 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 407

Query: 138 RKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLEN 197
           R L+ L ++ N L  +P  LP+ L  L++  N++R +     +GL  +  + +  N L  
Sbjct: 408 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 467

Query: 198 SGFEPGAFDGLKLNYLR 214
               PG +  L+   +R
Sbjct: 468 GDIGPGTWHELQALQVR 484


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score =  113 bits (283), Expect = 2e-25
 Identities = 93/333 (27%), Positives = 147/333 (44%), Gaps = 25/333 (7%)

Query: 7   LVSLLALSQALPFEQRGFWDFTL-----------DDGPFMMNDEEASGADTSGVLDPDSV 55
           L  L +LSQA   +   +W   L           D  P+   +    G D        S 
Sbjct: 9   LAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSP 68

Query: 56  TPTYSAMCPFGCHCHLR---VVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKG 112
           +P     CP  C C       + C +  LK +P  +      +  QNN I+ +++  F  
Sbjct: 69  SPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDN 127

Query: 113 LQHLYALVLVNNKIS--KIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNR 170
              L  + L  N+I+  K+  K FS LR L++LY+  N+L  +P  LP SL EL +  N+
Sbjct: 128 ATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQ 187

Query: 171 IRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPE 229
           I +VP     GL N+  + +  N ++  G    +  GL+ L  L +S   L  +P  LP 
Sbjct: 188 ISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPS 244

Query: 230 TLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNK 288
            L +L+++HN +  +         KL  + L HN +      S +F   +L EL L  N+
Sbjct: 245 ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304

Query: 289 LARVPSGLPDLKLLQVVYLHSNNITKVGVNDFC 321
           L ++P   P    L+ +YL  N I +  ++ FC
Sbjct: 305 LQKIP---PVNTNLENLYLQGNRINEFSISSFC 334


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score =  113 bits (283), Expect = 2e-25
 Identities = 82/271 (30%), Positives = 132/271 (48%), Gaps = 37/271 (13%)

Query: 61  AMCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNND----------------- 101
           A CP  CHCH  L+ V C  +GL+ +PK +S  T LL+LQ N+                 
Sbjct: 21  AACPQNCHCHSDLQHVICDKVGLQKIPK-VSEKTKLLNLQRNNFPVLAANSFRAMPNLVS 79

Query: 102 -------ISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
                  I E+    F+GL+ L  L L +N I  +   AF  L +L  LY+  N + E+P
Sbjct: 80  LHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELP 139

Query: 155 PNLPSSLVE---LRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-L 210
             L S LV    L++++N+IR++  G F G +++  + +  N L  S  +PGA D ++ L
Sbjct: 140 RGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENAL--SSLQPGALDDVENL 197

Query: 211 NYLRISEAKLTGIPKDLPETL---NELHLDHNKIQAIELEDLLRYSK-LYRLGLGHNQIR 266
               +   +L+  P      L    EL L HN +++I       + + L  L L +  + 
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257

Query: 267 MIENGSLSFLPTLRELHLDNNKLARVPSGLP 297
              +G+   + TL+ +HL+NN+L ++PS  P
Sbjct: 258 KFSDGAFLGVTTLKHVHLENNRLNQLPSNFP 288



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 95  LDLQNNDISELRKDDFKGL-QHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEI 153
           L L +N +  +  + F+   ++L  L L N  + K  + AF  +  L+ +++  N L ++
Sbjct: 224 LKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQL 283

Query: 154 PPNLP-SSLVELRIHDN 169
           P N P  SL  L + +N
Sbjct: 284 PSNFPFDSLETLALTNN 300


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score =  111 bits (277), Expect = 1e-24
 Identities = 88/263 (33%), Positives = 122/263 (46%), Gaps = 26/263 (9%)

Query: 63  CPFGCHC-HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121
           CP  C C  +  V C  L L+  P  I+     L LQNN + EL  ++   L  L  L L
Sbjct: 44  CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103

Query: 122 VNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVF 179
            NN IS   + ++AF  L +LQ L ++ N                   +N I KVP+G  
Sbjct: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHN------------------KNNLISKVPRGAL 145

Query: 180 SGLRNMNCIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDH 238
           S    +  + +  N L +SG +   F  L  L YL +S  +LT +P  LP TL  LHL  
Sbjct: 146 SRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGR 205

Query: 239 NKIQAIELEDLLRYSKLYRLGLGHNQIRM--IENGSLSFLPTLRELHLDNNKLARVPSGL 296
           N+I+ +E   L     L  L L HNQ+    +  G+L  L  L  LHL  N L RVP  L
Sbjct: 206 NRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL 265

Query: 297 PDLKLLQVVYLHSNNITKVGVND 319
           P  + L+ + L  N++  +G  D
Sbjct: 266 P--RRLRALVLPHNHVAALGARD 286



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 80  GLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPL 137
           GL  VP  +      L L +N ++ L   D      L  L L  N+++  ++H +AF  L
Sbjct: 257 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 316

Query: 138 RKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLEN 197
           R L+ L ++ N L  +P  LP+ L  L++  N++R +     +GL  +  + +  N L  
Sbjct: 317 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 376

Query: 198 SGFEPGAFDGLKLNYLR 214
               PG +  L+   +R
Sbjct: 377 GDIGPGTWHELQALQVR 393


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score =  109 bits (272), Expect = 4e-24
 Identities = 83/297 (27%), Positives = 137/297 (46%), Gaps = 34/297 (11%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV 122
           CP  C C  ++V C       +P+ IS  +  L L+ N I +L+ + F GL  L  L L 
Sbjct: 34  CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93

Query: 123 NNKISKIHEKAFSPLRKLQKLYISKNHLVEI-------PPNLPS---------------- 159
           +N IS + E AF  +R+L++L +S N +  +        PNL +                
Sbjct: 94  HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQF 153

Query: 160 ----SLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG-LKLNYLR 214
                L+ L +  N ++ VP  VF   RN++ +++G N L +      AF G LKL  L 
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRS--LSRNAFAGLLKLKELH 211

Query: 215 ISEAKLTGIP-KDLPETLN--ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENG 271
           +   + + I     P   N   ++L  N+I++I       +S L+ L L  N I+ IE G
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPG 271

Query: 272 SLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVK 328
           +   LP L++L+LD+NKL  +     +  +  +    S N+ +      CP+ + +K
Sbjct: 272 TFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECS-RSICPLFYWLK 327


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score =  109 bits (272), Expect = 4e-24
 Identities = 83/297 (27%), Positives = 137/297 (46%), Gaps = 34/297 (11%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV 122
           CP  C C  ++V C       +P+ IS  +  L L+ N I +L+ + F GL  L  L L 
Sbjct: 34  CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93

Query: 123 NNKISKIHEKAFSPLRKLQKLYISKNHLVEI-------PPNLPS---------------- 159
           +N IS + E AF  +R+L++L +S N +  +        PNL +                
Sbjct: 94  HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQF 153

Query: 160 ----SLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG-LKLNYLR 214
                L+ L +  N ++ VP  VF   RN++ +++G N L +      AF G LKL  L 
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRS--LSRNAFAGLLKLKELH 211

Query: 215 ISEAKLTGIP-KDLPETLN--ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENG 271
           +   + + I     P   N   ++L  N+I++I       +S L+ L L  N I+ IE G
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPG 271

Query: 272 SLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVK 328
           +   LP L++L+LD+NKL  +     +  +  +    S N+ +      CP+ + +K
Sbjct: 272 TFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECS-RSICPLFYWLK 327


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score =  106 bits (265), Expect = 3e-23
 Identities = 86/281 (30%), Positives = 134/281 (47%), Gaps = 13/281 (4%)

Query: 48  GVLDPDSVTPTYSAMCPFGCHCHL-RVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR 106
           G   P    P    +C   C C   R V CS  GL +VP+ +S  T  LD+  N+I++L 
Sbjct: 17  GSAGPSGAAPP---LCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLP 73

Query: 107 KDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVE 163
           +D FK    L  L L  N +S IH KA S L++L+ L +  N L  +P       S+L  
Sbjct: 74  EDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQS 133

Query: 164 LRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGI 223
           LR+  N I  VP+  F GL  +  + +  N L      P   +   L  L ++  K++ I
Sbjct: 134 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHP-LSNLPTLQALTLALNKISSI 192

Query: 224 PKDLPETLNE---LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR 280
           P      L+    LHL +NKI+++          L  L L +N +      ++  LP+L+
Sbjct: 193 PDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ-AIKALPSLK 251

Query: 281 ELHLDNNKLARVPSGLPD-LKLLQVVYLHSNNITKVGVNDF 320
           EL   +N ++ +P G  D   LL+ ++L+ N ++ VG + F
Sbjct: 252 ELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAF 292



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 36/129 (27%), Positives = 62/129 (48%), Gaps = 2/129 (1%)

Query: 112 GLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPP-NLPSSLVELRIHDNR 170
           G  HL +L L   KIS I        + L+ L +S N++ ++P  N   +L E+ +  N+
Sbjct: 317 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQ 376

Query: 171 IRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET 230
           I ++ +G F GL ++  +++  N +        A  G  +  L +S  +LT  P +    
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLG-PITNLDVSFNELTSFPTEGLNG 435

Query: 231 LNELHLDHN 239
           LN+L L  N
Sbjct: 436 LNQLKLVGN 444



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 25/75 (33%), Positives = 40/75 (53%)

Query: 95  LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
           + LQ N I ++++  F+GL  L  L L  N I +IH +AF+ L  +  L +S N L   P
Sbjct: 370 ISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFP 429

Query: 155 PNLPSSLVELRIHDN 169
               + L +L++  N
Sbjct: 430 TEGLNGLNQLKLVGN 444



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 5/127 (3%)

Query: 70  HLRVVQCSDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
           HL  +  +   + S+P  +  +  +L   DL  N+I +L    F G   L  + L  N+I
Sbjct: 320 HLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQRNQI 377

Query: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 186
            +I E  F  L  L+ L +S+N + EI     ++L  +   D    ++      GL  +N
Sbjct: 378 YQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLN 437

Query: 187 CIEMGGN 193
            +++ GN
Sbjct: 438 QLKLVGN 444


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  106 bits (265), Expect = 3e-23
 Identities = 84/262 (32%), Positives = 112/262 (42%), Gaps = 29/262 (11%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR-KDDFKGLQHLYALVL 121
           CP  C C    + C+D  L S+P  I  D T L LQNN I+      D K L        
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLL------- 83

Query: 122 VNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG 181
                            K++++Y+  N L E P NLP  + EL + +N IR +     S 
Sbjct: 84  -----------------KVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSK 126

Query: 182 LRNMNCIEMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK 240
           +  +  + +  N +     E GAF D   L  L +S   L+ IP  LP T+ EL LD N+
Sbjct: 127 IPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNR 186

Query: 241 IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF--LPTLRELHLDNNKLARVPSGLPD 298
           I  I    L   + L RL L  N +     G   F  L  L EL L  N L   P  LP 
Sbjct: 187 ISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPG 246

Query: 299 LKLLQVVYLHSNNITKVGVNDF 320
              L+ +YL  N+I +V  N F
Sbjct: 247 TN-LRKLYLQDNHINRVPPNAF 267



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 5/162 (3%)

Query: 50  LDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDD 109
           LD +SV+        F    +LR++  S   L ++P  +      L L +N IS +    
Sbjct: 135 LDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPS 194

Query: 110 FKGLQHLYALVLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLP-SSLVELRI 166
            +GL  L  LVL  N ++   + +K F  L  L +L + +N L   P NLP ++L +L +
Sbjct: 195 LQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYL 254

Query: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL 208
            DN I +VP   FS LR +  ++M  N L N     G FD L
Sbjct: 255 QDNHINRVPPNAFSYLRQLYRLDMSNNNLSN--LPQGIFDDL 294


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  106 bits (265), Expect = 3e-23
 Identities = 84/262 (32%), Positives = 112/262 (42%), Gaps = 29/262 (11%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELR-KDDFKGLQHLYALVL 121
           CP  C C    + C+D  L S+P  I  D T L LQNN I+      D K L        
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLL------- 83

Query: 122 VNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG 181
                            K++++Y+  N L E P NLP  + EL + +N IR +     S 
Sbjct: 84  -----------------KVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSK 126

Query: 182 LRNMNCIEMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK 240
           +  +  + +  N +     E GAF D   L  L +S   L+ IP  LP T+ EL LD N+
Sbjct: 127 IPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNR 186

Query: 241 IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF--LPTLRELHLDNNKLARVPSGLPD 298
           I  I    L   + L RL L  N +     G   F  L  L EL L  N L   P  LP 
Sbjct: 187 ISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPG 246

Query: 299 LKLLQVVYLHSNNITKVGVNDF 320
              L+ +YL  N+I +V  N F
Sbjct: 247 TN-LRKLYLQDNHINRVPPNAF 267



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 5/162 (3%)

Query: 50  LDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDD 109
           LD +SV+        F    +LR++  S   L ++P  +      L L +N IS +    
Sbjct: 135 LDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPS 194

Query: 110 FKGLQHLYALVLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLP-SSLVELRI 166
            +GL  L  LVL  N ++   + +K F  L  L +L + +N L   P NLP ++L +L +
Sbjct: 195 LQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYL 254

Query: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL 208
            DN I +VP   FS LR +  ++M  N L N     G FD L
Sbjct: 255 QDNHINRVPPNAFSYLRQLYRLDMSNNNLSN--LPQGIFDDL 294


>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
           sapiens]
          Length = 660

 Score =  104 bits (259), Expect = 1e-22
 Identities = 73/211 (34%), Positives = 102/211 (48%), Gaps = 4/211 (1%)

Query: 81  LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKI--HEKAFSPLR 138
           L   P  +  +  +L LQ N+I  + +     L  L  L L +N IS +   + AF    
Sbjct: 100 LDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159

Query: 139 KLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENS 198
            L+ L++SKNHL  +P  LP  L ELR+ +NRI  +    F  L ++  + + GN L N 
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNK 219

Query: 199 GFEPGAFDGL-KLNYLRISEAKLTGIPKDLPET-LNELHLDHNKIQAIELEDLLRYSKLY 256
           G   G F  L KL    I    L+  P DLP T L  L+L  N+I  I L       KL 
Sbjct: 220 GIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279

Query: 257 RLGLGHNQIRMIENGSLSFLPTLRELHLDNN 287
           RL + +NQ+RM+  G    L  L++L   NN
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310



 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 27/261 (10%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV 122
           CP  C C    V C++  L SVP  I    T+L L NN I+      F    H       
Sbjct: 36  CPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA---GFPAELH------- 85

Query: 123 NNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGL 182
              +  +H            +Y+  N L E P NLP ++  L + +N I+ + +   + L
Sbjct: 86  --NVQSVHT-----------VYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQL 132

Query: 183 RNMNCIEMGGNPLENSGFEPGAF-DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKI 241
             +  + +  N +   G E GAF + + L  L +S+  L+ +P  LP  L EL +D N+I
Sbjct: 133 LKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRI 192

Query: 242 QAIELEDLLRYSKLYRLGLGHNQI--RMIENGSLSFLPTLRELHLDNNKLARVPSGLPDL 299
             I        + L RL +  N +  + I  G+ S L  L+E  +  N L+  P  LP  
Sbjct: 193 AVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGT 252

Query: 300 KLLQVVYLHSNNITKVGVNDF 320
            L++ +YL  N I  + +  F
Sbjct: 253 HLIR-LYLQDNQINHIPLTAF 272



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 27/151 (17%)

Query: 71  LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISK-- 128
           L+++  S   L SVP  +  D   L +  N I+ +    F+ L  L  L++  N ++   
Sbjct: 161 LKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKG 220

Query: 129 IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS-------------------------LVE 163
           I E  FS L KL++  I +N L   PP+LP +                         L  
Sbjct: 221 IAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLER 280

Query: 164 LRIHDNRIRKVPKGVFSGLRNMNCIEMGGNP 194
           L I +N++R + +GVF  L N+  +    NP
Sbjct: 281 LDISNNQLRMLTQGVFDNLSNLKQLTARNNP 311


>gi|51317373 netrin-G1 ligand [Homo sapiens]
          Length = 640

 Score =  103 bits (258), Expect = 2e-22
 Identities = 84/256 (32%), Positives = 122/256 (47%), Gaps = 9/256 (3%)

Query: 63  CPFGCHC--HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 120
           CP  C C      V C    L+ VP  IS +T LL+L  N I  ++ + FK L+HL  L 
Sbjct: 47  CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106

Query: 121 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN---LPSSLVELRIHDNRIRKVPKG 177
           L  N I  I   AF+ L  L  L +  N L  IP       S L EL + +N I  +P  
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166

Query: 178 VFSGLRNMNCIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLP-ETLNELH 235
            F+ + ++  +++ G     S    GAF+GL  L YL ++   L  IP   P   L+EL 
Sbjct: 167 AFNRIPSLRRLDL-GELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELD 225

Query: 236 LDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSG 295
           L  N + AI          L +L +  +QI++IE  +   L +L E++L +N L  +P  
Sbjct: 226 LSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHD 285

Query: 296 L-PDLKLLQVVYLHSN 310
           L   L  L+ ++LH N
Sbjct: 286 LFTPLHHLERIHLHHN 301



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 24/127 (18%)

Query: 70  HLRVVQCSDLGLKSVPKEISPDTTL--LDLQNNDISELRKDDFKGLQHLYALVLVNNKIS 127
           +LR +  +   L+ +P  ++P   L  LDL  N +S +R   F+GL HL  L ++ ++I 
Sbjct: 198 NLRYLNLAMCNLREIPN-LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQ 256

Query: 128 KIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNC 187
            I   AF  L+                     SLVE+ +  N +  +P  +F+ L ++  
Sbjct: 257 VIERNAFDNLQ---------------------SLVEINLAHNNLTLLPHDLFTPLHHLER 295

Query: 188 IEMGGNP 194
           I +  NP
Sbjct: 296 IHLHHNP 302


>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
          Length = 713

 Score =  103 bits (257), Expect = 2e-22
 Identities = 84/257 (32%), Positives = 119/257 (46%), Gaps = 11/257 (4%)

Query: 63  CPFGCHCHLRV--VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 120
           CP  C C  +   V C+   L  VP  I  +T  L+LQ N I  +R D FK L+HL  L 
Sbjct: 57  CPVACSCSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQ 116

Query: 121 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKG 177
           L  N + KI   AF+ L  L  L +  N L  +P       S L EL + +N I  +P  
Sbjct: 117 LSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSY 176

Query: 178 VFSGLRNMNCIEMGG-NPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPK-DLPETLNEL 234
            F+ + ++  +++G    LE       AF+GL  L YL +    L  IP       L EL
Sbjct: 177 AFNRVPSLRRLDLGELKRLEY--ISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEEL 234

Query: 235 HLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPS 294
            L  N++  I        + L +L L H Q+  IE  +   L +L EL+L +N L  +P 
Sbjct: 235 ELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPH 294

Query: 295 GL-PDLKLLQVVYLHSN 310
            L   L  L+ V+L+ N
Sbjct: 295 DLFTPLHRLERVHLNHN 311


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score =  102 bits (254), Expect = 5e-22
 Identities = 93/304 (30%), Positives = 137/304 (45%), Gaps = 53/304 (17%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV 122
           CP  C C    V C  L L+SVP+ I  +T  LDL  N+I+ + K DF GL+HL  L L+
Sbjct: 28  CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLM 87

Query: 123 NNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPKGVF 179
            NKIS I   AF  L++L++L +++NHL   P  L    + L  L + +N+I+ +P+  F
Sbjct: 88  ENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAF 147

Query: 180 SGLRNMNCIEMGGNPLENSGFEPGAFDGLK---------LNYLRISEAKLTGIPKDLPET 230
            G  ++  +++  N +  S  E GAF  L+          N  R+S A    +PK     
Sbjct: 148 RGAVDIKNLQLDYNQI--SCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205

Query: 231 L--NELHLDHNKIQAIELEDLLRYSKLYRLGL-----------GHN-----QIRMIENGS 272
           L  N L+ D        L D LR     R+GL           GHN     +   + +G 
Sbjct: 206 LHSNNLYCD---CHLAWLSDWLRQRP--RVGLYTQCMGPSHLRGHNVAEVQKREFVCSGH 260

Query: 273 LSFL-PTLRELH------LDNN-------KLARVPSGLPDLKLLQVVYLHSNNITKVGVN 318
            SF+ P+   LH        NN        L  +P+ LP+   +  + L  N I  +   
Sbjct: 261 QSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPE--TITEIRLEQNTIKVIPPG 318

Query: 319 DFCP 322
            F P
Sbjct: 319 AFSP 322



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 92/396 (23%), Positives = 149/396 (37%), Gaps = 107/396 (27%)

Query: 55  VTPTYSAM-CPFGCHCHLRVVQCSDLGLKSVPKEISPDTT-------------------- 93
           + P+ S + CP  C C   +V C   GL  +P  +    T                    
Sbjct: 264 MAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPY 323

Query: 94  ----LLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNH 149
                +DL NN ISEL  D F+GL+ L +LVL  NKI+++ +  F  L  LQ L ++ N 
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANK 383

Query: 150 L----VEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAF 205
           +    V+   +L  +L  L ++DN+++ + KG FS LR +  + +  NP           
Sbjct: 384 INCLRVDAFQDL-HNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLA 442

Query: 206 DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIE-------------------- 245
           D L  N +  S A+ T   +   + + ++     +  A E                    
Sbjct: 443 DYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFA 502

Query: 246 ---------------------LEDLLRYSKLY--RLGLGHNQIRMIE-NGSLSFLPTLRE 281
                                L  +  +   Y   L L +N+  ++E  G    LP LR+
Sbjct: 503 DLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRK 562

Query: 282 LHLDNNKLARVPSG-------------------------LPDLKLLQVVYLHSNNITKVG 316
           ++  NNK+  +  G                            L+ L+ + L SN IT VG
Sbjct: 563 INFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVG 622

Query: 317 VNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATF 352
            + F  +G    R     +SL++N +    V P  F
Sbjct: 623 NDSF--IGLSSVRL----LSLYDNQIT--TVAPGAF 650



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 87/336 (25%), Positives = 127/336 (37%), Gaps = 84/336 (25%)

Query: 63  CPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDD-FKGLQHLYALVL 121
           CP  C C    V CS+  L  +P+ I   T  L L NN+ + L     FK L  L  +  
Sbjct: 506 CPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINF 565

Query: 122 VNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL------------------------ 157
            NNKI+ I E AF     + ++ ++ N L  +   +                        
Sbjct: 566 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 625

Query: 158 ---PSSLVELRIHDNRIRKVPKGVFSGLR------------NMNCIE------------M 190
               SS+  L ++DN+I  V  G F  L             N NC              +
Sbjct: 626 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIV 685

Query: 191 GGNP-------LENSGFEPGAF------DGLKLN-----------------YLRISEAKL 220
            GNP       L+    +  A       DG   N                  +R S   L
Sbjct: 686 TGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGL 745

Query: 221 TGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR 280
             +PK +P  + EL+LD N+   +  E L  Y  L  + L +N+I  + N S S +  L 
Sbjct: 746 KVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLL 804

Query: 281 ELHLDNNKLARVPSGLPD-LKLLQVVYLHSNNITKV 315
            L L  N+L  +P    D LK L+++ LH N+I+ V
Sbjct: 805 TLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVV 840



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 56/202 (27%), Positives = 79/202 (39%), Gaps = 63/202 (31%)

Query: 17  LPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQC 76
           +P +     DFT DDG                  D +S +P   + CP  C C   VV+C
Sbjct: 700 IPIQDVAIQDFTCDDGN-----------------DDNSCSPL--SRCPTECTCLDTVVRC 740

Query: 77  SDLGLKSVPKEISPDTT-----------------------LLDLQNNDISELRKDDFKGL 113
           S+ GLK +PK I  D T                       L+DL NN IS L    F  +
Sbjct: 741 SNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNM 800

Query: 114 QHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRK 173
             L  L+L  N++  I  + F  L+ L+                      L +H N I  
Sbjct: 801 TQLLTLILSYNRLRCIPPRTFDGLKSLRL---------------------LSLHGNDISV 839

Query: 174 VPKGVFSGLRNMNCIEMGGNPL 195
           VP+G F+ L  ++ + +G NPL
Sbjct: 840 VPEGAFNDLSALSHLAIGANPL 861



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 57/244 (23%), Positives = 105/244 (43%), Gaps = 16/244 (6%)

Query: 54  SVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFK-G 112
           ++   + A  PF C CHL+ +    L    +    +  T+   L N  I +++   F+  
Sbjct: 421 AIQTMHLAQNPFICDCHLKWL-ADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCS 479

Query: 113 LQHLYALVLVNNKISKIHEKAFSPLRKLQK-------LYISKNHLVEIPPNLPSSLVELR 165
            +  Y +    +  SK+    F+ L   +K       +  S   L +IP ++P    ELR
Sbjct: 480 AKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELR 539

Query: 166 IHDNRIRKV-PKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGI 223
           +++N    +   G+F  L  +  I    N +  +  E GAF+G   +N + ++  +L  +
Sbjct: 540 LNNNEFTVLEATGIFKKLPQLRKINFSNNKI--TDIEEGAFEGASGVNEILLTSNRLENV 597

Query: 224 PKDL---PETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR 280
              +    E+L  L L  N+I  +  +  +  S +  L L  NQI  +  G+   L +L 
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657

Query: 281 ELHL 284
            L+L
Sbjct: 658 TLNL 661


>gi|198041768 synleurin [Homo sapiens]
          Length = 622

 Score =  102 bits (253), Expect = 7e-22
 Identities = 87/292 (29%), Positives = 135/292 (46%), Gaps = 34/292 (11%)

Query: 69  CHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISK 128
           C  R + C +LGL S+PK     T  L L  N+IS + + +  GL  L AL L N+ I  
Sbjct: 39  CTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILY 98

Query: 129 IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELR---IHDNRIRKVPKGVFSGLRNM 185
           ++ KAF  LR L  L+++ N +  + P +   L+ LR   +  N++  VP+GVF+ L ++
Sbjct: 99  VYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSV 158

Query: 186 NCIEMGGNPLENSGFEPGAFDGL---------KLNYLRISEA----------------KL 220
             + +  N L   G   G F G+           N LRISE+                 L
Sbjct: 159 QYLNLQRNRLTVLG--SGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNL 216

Query: 221 TGIPK---DLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLP 277
           T +P    ++ ++L  L L HN I+AI+       + L  L L +++IR +     S + 
Sbjct: 217 TKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGIN 276

Query: 278 TLRELHLDNNKLARVPSG-LPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVK 328
            L+ L L +N L  + S     LK L  + L  N I  +  + F  MG  +K
Sbjct: 277 NLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLK 328


>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score =  102 bits (253), Expect = 7e-22
 Identities = 89/307 (28%), Positives = 140/307 (45%), Gaps = 20/307 (6%)

Query: 25  WDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRV---VQCSDLGL 81
           WD   D  P   +D+  +G      +D       Y+  C   C C       + C +  L
Sbjct: 27  WDEDYDQEP---DDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKL 83

Query: 82  KSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPLRK 139
           K++P  I      L LQ N+I  +  + F    HL  + L +NKI   KI    F+ L  
Sbjct: 84  KTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPN 142

Query: 140 LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSG 199
           L +L++  N+L E P  LP SL  L +  N I K+      GL N+  +++  N L +S 
Sbjct: 143 LLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSL 202

Query: 200 FEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRL 258
            +   F  + KL  L +   +L  +P  LP +L  L L++N I +I  +   +  KL+ L
Sbjct: 203 LKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTL 262

Query: 259 GLGHNQIRMIENGSLSFLPTLRELHLDNNKLAR---VPSGLPDLKLLQVVYLHSNNITKV 315
            + HN+++ I     + LP + EL + +NKL +   +P  L  L      YL +N I K+
Sbjct: 263 RMSHNKLQDIPYNIFN-LPNIVELSVGHNKLKQAFYIPRNLEHL------YLQNNEIEKM 315

Query: 316 GVNDFCP 322
            +   CP
Sbjct: 316 NLTVMCP 322



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 11/194 (5%)

Query: 81  LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI--SKIHEKAFSPLR 138
           L+  P  +      L L  N+IS+L+ +   GL +L  L L  N +  S + +K F+ + 
Sbjct: 153 LEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKME 212

Query: 139 KLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENS 198
           KL +L +  N L  +PP LPSSL+ L + +N I  +P+  F  L  ++ + M  N L++ 
Sbjct: 213 KLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDI 272

Query: 199 GFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE------DLLRY 252
            +    F+   +  L +   KL      +P  L  L+L +N+I+ + L       D L Y
Sbjct: 273 PY--NIFNLPNIVELSVGHNKLKQ-AFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHY 329

Query: 253 SKLYRLGLGHNQIR 266
             L  + +  N+++
Sbjct: 330 HHLTYIRVDQNKLK 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.140    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,560,159
Number of Sequences: 37866
Number of extensions: 677151
Number of successful extensions: 3848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 1521
Number of HSP's gapped (non-prelim): 923
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.