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Search of human proteins with 42560248
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42560248 POU domain, class 5, transcription factor 1 isoform
1 [Homo sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42560248 POU domain, class 5, transcription factor 1 isoform ... 754 0.0
gi|227430410 POU class 5 homeobox 1B [Homo sapiens] 716 0.0
gi|116235491 POU domain, class 5, transcription factor 1 isoform... 458 e-129
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap... 274 1e-73
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s... 202 4e-52
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 190 1e-48
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s... 190 2e-48
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 187 1e-47
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap... 175 5e-44
gi|42476164 POU class 2 homeobox 1 [Homo sapiens] 173 2e-43
gi|148664218 POU transcription factor [Homo sapiens] 166 2e-41
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 142 5e-34
gi|170650730 pituitary specific transcription factor 1 isoform b... 141 8e-34
gi|4505955 pituitary specific transcription factor 1 isoform alp... 141 8e-34
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 129 3e-30
gi|4505965 POU class 4 homeobox 3 [Homo sapiens] 125 4e-29
gi|223890225 POU class 6 homeobox 1 [Homo sapiens] 115 5e-26
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 87 3e-17
gi|24497589 aristaless related homeobox [Homo sapiens] 52 6e-07
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 49 7e-06
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 48 1e-05
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 48 2e-05
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 47 2e-05
gi|7110735 ventral anterior homeobox 2 [Homo sapiens] 47 3e-05
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 47 3e-05
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 47 3e-05
gi|61969666 arginine-fifty homeobox [Homo sapiens] 47 3e-05
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 45 8e-05
gi|11386181 H2.0-like homeobox [Homo sapiens] 45 8e-05
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 45 1e-04
>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
[Homo sapiens]
Length = 360
Score = 754 bits (1948), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI
Sbjct: 1 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
Query: 61 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG 120
PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG
Sbjct: 61 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG 120
Query: 121 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS 180
AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
Sbjct: 121 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS 180
Query: 181 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR 240
QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR
Sbjct: 181 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR 240
Query: 241 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 300
VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
Sbjct: 241 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 300
Query: 301 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360
AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Sbjct: 301 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360
>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
Length = 359
Score = 716 bits (1849), Expect = 0.0
Identities = 345/360 (95%), Positives = 348/360 (96%), Gaps = 1/360 (0%)
Query: 1 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
MAGHLASDFAFSPPPGGGGDGP G EPGWVDP TWLSFQGPPGGPGIGPGVGPGSEVWGI
Sbjct: 1 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
Query: 61 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG 120
PPCPPPYE CGGMAYCGPQVGVGLVPQGGLETSQPE EAGVGVESNS+GASPEPCTV PG
Sbjct: 61 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG 120
Query: 121 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS 180
AVKLEKEKLEQNPE+SQDIKALQKELEQFAKLLKQKRITLGYTQADVGL LGVLFGKVFS
Sbjct: 121 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS 180
Query: 181 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR 240
Q TICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETL+QARKRKRTSIENR
Sbjct: 181 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR 240
Query: 241 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 300
VRGNLENLFLQCPKPTL QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
Sbjct: 241 VRGNLENLFLQCPKPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 299
Query: 301 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360
AGSPFSGGPVSFP APGPHFGTPGYGSPHFTALYSSVPFPEGE FPPVSV TLGSPMHSN
Sbjct: 300 AGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359
>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
[Homo sapiens]
Length = 265
Score = 458 bits (1179), Expect = e-129
Identities = 225/226 (99%), Positives = 226/226 (100%)
Query: 135 ESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 194
+SQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF
Sbjct: 40 QSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 99
Query: 195 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 254
KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK
Sbjct: 100 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 159
Query: 255 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 314
PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL
Sbjct: 160 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 219
Query: 315 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360
APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Sbjct: 220 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 265
>gi|23463326 POU domain class 5, transcription factor 2 [Homo
sapiens]
Length = 328
Score = 274 bits (700), Expect = 1e-73
Identities = 169/359 (47%), Positives = 207/359 (57%), Gaps = 40/359 (11%)
Query: 1 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGG----PGIGPGVGPGSE 56
MAGH S+ F P PG GG GP GP P VD TWLS Q PG P + PG+ PG +
Sbjct: 1 MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD 59
Query: 57 VWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCT 116
VW IP P P+EF G +A C P++G EAG + S+GA P P
Sbjct: 60 VWRIPLGPLPHEFRGWIAPCRPRLGAS--------------EAGDWLRRPSEGALPGPYI 105
Query: 117 VTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFG 176
KL +DI + KEL+Q AK L+QKR++LGY+QADVG+ +G LFG
Sbjct: 106 ALRSIPKLPPP---------EDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG 156
Query: 177 KVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQ-ARKRKRT 235
KV SQTTICRFEA QLS NM KLRPLL+KW++E + ENL +CK E ++Q + K +R
Sbjct: 157 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRA 215
Query: 236 SIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR 295
S E R+ +LE F +CPKPT QQISHIA L L+KDVVRVWF NR + G R ++D + R
Sbjct: 216 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR 275
Query: 296 EDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLG 354
E AG P G PV F L G P PH+T LYS+ G A TTLG
Sbjct: 276 EIVGTAGPPCPGAPVCFHLG----LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLG 324
>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
sapiens]
Length = 451
Score = 202 bits (514), Expect = 4e-52
Identities = 136/320 (42%), Positives = 168/320 (52%), Gaps = 56/320 (17%)
Query: 9 FAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYE 68
+A + PGGGG G G L+ G GPG+ + + P PPP+
Sbjct: 159 YAQAAYPGGGGGGLAG----------MLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHL 208
Query: 69 FCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEK 128
G A+ G GGL + G G +S G
Sbjct: 209 GAHGHAH-------GHAHAGGLHAAAAHLHPGAGGGGSSVG------------------- 242
Query: 129 LEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFE 188
E S + +LEQFAK KQ+RI LG+TQADVGL LG L+G VFSQTTICRFE
Sbjct: 243 -----EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 297
Query: 189 ALQLSFKNMCKLRPLLQKWVEEADNNE----NLQEICKAETLVQARKR-KRTSIENRVRG 243
ALQLSFKNMCKL+PLL KW+EE D++ NL +I Q RKR KRTSIE V+G
Sbjct: 298 ALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKG 352
Query: 244 NLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFE 299
LE+ FL+CPKP+ +I+ +A L LEK+VVRVWFCNRRQK KR + + + +D
Sbjct: 353 ALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVY 412
Query: 300 AAGS-PFSGGPVSFPLAPGP 318
A G GG S P AP P
Sbjct: 413 APGELGPGGGGASPPSAPPP 432
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 190 bits (483), Expect = 1e-48
Identities = 103/193 (53%), Positives = 129/193 (66%), Gaps = 3/193 (1%)
Query: 129 LEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFE 188
L + S + +LEQFAK KQ+RI LG+TQADVGL LG L+G VFSQTTICRFE
Sbjct: 305 LNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 364
Query: 189 ALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENL 248
ALQLSFKNMCKL+PLL KW+EEAD++ +++KRTSIE V+G LE+
Sbjct: 365 ALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESH 424
Query: 249 FLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGG 308
FL+CPKP+ Q+I+++A L LEK+VVRVWFCNRRQK KR + Q++ + S G
Sbjct: 425 FLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQV--G 482
Query: 309 PVSFPLAPGPHFG 321
VS P PH G
Sbjct: 483 TVSAD-TPPPHHG 494
>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
sapiens]
Length = 361
Score = 190 bits (482), Expect = 2e-48
Identities = 114/234 (48%), Positives = 135/234 (57%), Gaps = 16/234 (6%)
Query: 58 WGIPPCPPPYEFCGGM---AYCGPQVGV-GLVPQGGLETSQPEGEAGVGVESNSDGASPE 113
WG P P P G Y P V G++ GGL T P A +S
Sbjct: 114 WGASPAPNPSITSSGQPLNVYSQPGFTVSGMLEHGGL-TPPP---AAASAQSLHPVLREP 169
Query: 114 PCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGV 173
P G+ + E+ P ELEQFAK KQ+RI LG+TQADVGL LG
Sbjct: 170 PDHGELGSHHCQDHSDEETPTSD--------ELEQFAKQFKQRRIKLGFTQADVGLALGT 221
Query: 174 LFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK 233
L+G VFSQTTICRFE LQLSFKNMCKL+PLL KW+EEAD++ +++K
Sbjct: 222 LYGNVFSQTTICRFEGLQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKK 281
Query: 234 RTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
RTSIE V+G LE FL+CPKP Q+IS +A L LEK+VVRVWFCNRRQK KR
Sbjct: 282 RTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKR 335
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 187 bits (475), Expect = 1e-47
Identities = 94/156 (60%), Positives = 115/156 (73%), Gaps = 1/156 (0%)
Query: 132 NPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
+P +D +LEQFAK KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQ
Sbjct: 257 DPHSDEDTPT-SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 315
Query: 192 LSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQ 251
LSFKNMCKL+PLL KW+EEAD++ +++KRTSIE V+G LE+ FL+
Sbjct: 316 LSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLK 375
Query: 252 CPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
CPKP+ Q+I+ +A L LEK+VVRVWFCNRRQK KR
Sbjct: 376 CPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKR 411
Score = 29.3 bits (64), Expect = 5.7
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 7/49 (14%)
Query: 16 GGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGV-----GPGSEVWG 59
GGGG G GG G D W + P G P I P V G G E+ G
Sbjct: 74 GGGGGGGGGGGGGGGDGSPWST--SPLGQPDIKPSVVVQQGGRGDELHG 120
>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
sapiens]
Length = 463
Score = 175 bits (444), Expect = 5e-44
Identities = 118/279 (42%), Positives = 151/279 (54%), Gaps = 51/279 (18%)
Query: 87 QGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKEL 146
QG L TSQP AG+ + P C P +PEE D++ EL
Sbjct: 152 QGALLTSQPR--AGLPTQ-------PPKCLEPPS-----------HPEEPSDLE----EL 187
Query: 147 EQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQK 206
EQFA+ KQ+RI LG+TQ DVGL +G L+G FSQTTI RFEAL LSFKNMCKL+PLL+K
Sbjct: 188 EQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK 247
Query: 207 WVEEADN----------NENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPT 256
W+ +A+ N+ + L R++KRTSIE VR LE FL KPT
Sbjct: 248 WLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPT 307
Query: 257 LQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAP 316
++I IA+QL +EK+V+RVWFCNRRQK KR + A A P G P S+
Sbjct: 308 SEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA------APMLPSPGKPASY---- 357
Query: 317 GPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGS 355
PH TP G+ ++P + + +VTTL S
Sbjct: 358 SPHMVTPQGGA-------GTLPLSQASSSLSTTVTTLSS 389
>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
Length = 743
Score = 173 bits (438), Expect = 2e-43
Identities = 106/252 (42%), Positives = 141/252 (55%), Gaps = 28/252 (11%)
Query: 78 PQVGVGLVPQGGLETSQPEGEAGVGVESNSD---GASPEPCTVTPGAVKLEKEKLEQNPE 134
PQ GL+ L T P+ ++S + P T T A ++ Q+
Sbjct: 212 PQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTP 271
Query: 135 ESQDIKALQK-----ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEA 189
+ D +L++ ELEQFAK KQ+RI LG+TQ DVGL +G L+G FSQTTI RFEA
Sbjct: 272 KRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEA 331
Query: 190 LQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETL-------VQARKRKRTSIENRVR 242
L LSFKNMCKL+PLL+KW+ +A+N + + L + R++KRTSIE +R
Sbjct: 332 LNLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIR 391
Query: 243 GNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAG 302
LE FL+ KPT ++I+ IA QL +EK+V+RVWFCNRRQK KR
Sbjct: 392 VALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR-------------IN 438
Query: 303 SPFSGGPVSFPL 314
P SGG S P+
Sbjct: 439 PPSSGGTSSSPI 450
>gi|148664218 POU transcription factor [Homo sapiens]
Length = 436
Score = 166 bits (421), Expect = 2e-41
Identities = 99/216 (45%), Positives = 129/216 (59%), Gaps = 22/216 (10%)
Query: 78 PQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQ 137
PQ G GL Q P +E++ P+ + GA +E
Sbjct: 139 PQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGA------------DEPS 186
Query: 138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNM 197
D++ ELE+FAK KQ+RI LG+TQ DVGL +G L+G FSQTTI RFEAL LSFKNM
Sbjct: 187 DLE----ELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 242
Query: 198 CKLRPLLQKWVEEADNNENLQEICKAETL-----VQARKR-KRTSIENRVRGNLENLFLQ 251
CKL+PLL+KW+ +A+++ + + + V RKR KRTSIE +R LE F
Sbjct: 243 CKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQD 302
Query: 252 CPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
PKP+ ++IS IA+QL +EK+VVRVWFCNRRQK KR
Sbjct: 303 NPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 142 bits (358), Expect = 5e-34
Identities = 110/293 (37%), Positives = 143/293 (48%), Gaps = 38/293 (12%)
Query: 10 AFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEF 69
A P GGGG G GG GP GGPG G G GPG G P
Sbjct: 143 AHDGPGGGGGPGGGG---------------GPGGGPGGGGGGGPGGGGGG-----PGGGL 182
Query: 70 CGGMAYCGPQV---GVGLVPQGGLETSQPEG--EAGVGVESNSDGASPEPCTVTPGAVKL 124
GG A+ P + G P + P G G+ + GA+ G V
Sbjct: 183 LGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAA 242
Query: 125 EKEKLE----QNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-- 178
D +ELE FA+ KQ+RI LG TQADVG L L K+
Sbjct: 243 ASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANL--KIPG 300
Query: 179 ---FSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQA-RKRKR 234
SQ+TICRFE+L LS NM L+P+LQ W+EEA+ + +++ K E +KRKR
Sbjct: 301 VGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQR-EKMNKPELFNGGEKKRKR 359
Query: 235 TSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
TSI + +LE F P+P+ ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 360 TSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 412
>gi|170650730 pituitary specific transcription factor 1 isoform beta
[Homo sapiens]
Length = 317
Score = 141 bits (356), Expect = 8e-34
Identities = 81/170 (47%), Positives = 106/170 (62%), Gaps = 6/170 (3%)
Query: 126 KEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTIC 185
K KL + P + + +ELE+FA K +RI LGYTQ +VG L + G FSQTTIC
Sbjct: 140 KSKLVEEPIDMDSPEI--RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTIC 197
Query: 186 RFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGN 244
RFE LQLSFKN CKL+ +L KW+EEA E + + + RKRK RT+I +
Sbjct: 198 RFENLQLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDA 254
Query: 245 LENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 294
LE F + KP+ Q+I +A++L LEK+VVRVWFCNRRQ+ KR + Q
Sbjct: 255 LERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304
>gi|4505955 pituitary specific transcription factor 1 isoform alpha
[Homo sapiens]
Length = 291
Score = 141 bits (356), Expect = 8e-34
Identities = 81/170 (47%), Positives = 106/170 (62%), Gaps = 6/170 (3%)
Query: 126 KEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTIC 185
K KL + P + + +ELE+FA K +RI LGYTQ +VG L + G FSQTTIC
Sbjct: 114 KSKLVEEPIDMDSPEI--RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTIC 171
Query: 186 RFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGN 244
RFE LQLSFKN CKL+ +L KW+EEA E + + + RKRK RT+I +
Sbjct: 172 RFENLQLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDA 228
Query: 245 LENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 294
LE F + KP+ Q+I +A++L LEK+VVRVWFCNRRQ+ KR + Q
Sbjct: 229 LERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 278
>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
Length = 409
Score = 129 bits (325), Expect = 3e-30
Identities = 76/156 (48%), Positives = 105/156 (67%), Gaps = 9/156 (5%)
Query: 138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-----FSQTTICRFEALQL 192
D+ A ++LE FA+ KQ+RI LG TQADVG L L K+ SQ+TICRFE+L L
Sbjct: 250 DVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTL 307
Query: 193 SFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQA-RKRKRTSIENRVRGNLENLFLQ 251
S NM L+P+LQ W+EEA+ + +++ K E A +KRKRTSI + +LE F
Sbjct: 308 SHNNMIALKPILQAWLEEAEKSHR-EKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAI 366
Query: 252 CPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
P+P+ ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 367 QPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 402
>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
Length = 338
Score = 125 bits (315), Expect = 4e-29
Identities = 74/155 (47%), Positives = 100/155 (64%), Gaps = 7/155 (4%)
Query: 138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-----FSQTTICRFEALQL 192
D+++ +ELE FA+ KQ+RI LG TQADVG L L K+ SQ+TICRFE+L L
Sbjct: 179 DVESDPRELEAFAERFKQRRIKLGVTQADVGAALANL--KIPGVGSLSQSTICRFESLTL 236
Query: 193 SFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQC 252
S NM L+P+LQ W+EEA+ + RKRKRTSI + +LE F
Sbjct: 237 SHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQ 296
Query: 253 PKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
P+P+ ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 297 PRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331
>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
Length = 301
Score = 115 bits (289), Expect = 5e-26
Identities = 74/210 (35%), Positives = 114/210 (54%), Gaps = 14/210 (6%)
Query: 85 VPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQK 144
VPQ + + P A + ++ P C+ TP +L + P +D L+
Sbjct: 93 VPQPAVVIASPAPAA----KPSASAPIPITCSETPTVSQLVSKP--HTPSLDEDGINLE- 145
Query: 145 ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 204
E+ +FAK K +R++LG TQ VG L G +SQ+ ICRFE L ++ K+ KL+P+L
Sbjct: 146 EIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVL 205
Query: 205 QKWVEEA-----DNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQ 259
+KW+ EA + +NL E E ++++RTS + L F + P PT Q+
Sbjct: 206 EKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQE 263
Query: 260 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 289
I+ IA++L +++VVRVWFCNRRQ K +S
Sbjct: 264 ITEIAKELNYDREVVRVWFCNRRQTLKNTS 293
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 86.7 bits (213), Expect = 3e-17
Identities = 84/342 (24%), Positives = 139/342 (40%), Gaps = 57/342 (16%)
Query: 3 GHLASDFAFSPPPGGGGDGPGGPEPGWVDPRT---WLSFQGPPGGPGIGPGVGPGSEVWG 59
G + P PG G + V P T + QG IG + P G
Sbjct: 341 GQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400
Query: 60 IP--PCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTV 117
I P P G + Q VG G +A + +S +
Sbjct: 401 ITLSPIKP-----GQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSS 455
Query: 118 TPGAVKLEKEKLEQNPEESQ-DIKALQ-KELEQFAKLLKQKRITLGYTQADVGLTLGVLF 175
+ A+ + + L NP+ + ++ + +E+ +FAK K +R++LG TQ VG L
Sbjct: 456 SSSALSVGQ--LVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATE 513
Query: 176 GKVFSQTTICR------------------------------------FEALQLSFKNMCK 199
G +SQ+ ICR FE L ++ K+ K
Sbjct: 514 GPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQK 573
Query: 200 LRPLLQKWVEEADNN-----ENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 254
++P+L++W+ EA+ +NL E +E ++++RTS + L F +
Sbjct: 574 IKPVLERWMAEAEARHRAGMQNLTEFIGSEP--SKKRKRRTSFTPQALEILNAHFEKNTH 631
Query: 255 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQRE 296
P+ Q+++ IA++L +++VVRVWFCN+RQ K + Q E
Sbjct: 632 PSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHE 673
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 52.4 bits (124), Expect = 6e-07
Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 68/321 (21%)
Query: 60 IPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTP 119
+PP P E G P+ +G+ G S P G G E +
Sbjct: 183 VPPPPALDELGGPGGVTHPEERLGVAGGPG---SAPAAGGGTGTEDD------------- 226
Query: 120 GAVKLEKEKLEQNPEESQDIKALQKELEQFAK-----LLKQKRITLGYTQADVGLTLGVL 174
E+E LE +E ++ + L+ + E+ + LLK+ R + V T V
Sbjct: 227 -----EEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPR------RCPVAATGAVA 275
Query: 175 FGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKA------ETLVQ 228
+ T E +LS K L P E+A+ + +C + E L++
Sbjct: 276 AAAAAAVAT----EGGELSPKEELLLHP------EDAEGKDGEDSVCLSAGSDSEEGLLK 325
Query: 229 ARKRK-RTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
++R+ RT+ + LE F + P + +A +L L + V+VWF NRR K ++
Sbjct: 326 RKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRK 385
Query: 288 SSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTAL-------------- 333
AQ G PF GP+S P+ + PH AL
Sbjct: 386 REKAGAQT---HPPGLPFP-GPLSATHPLSPYLDASPF-PPHHPALDSAWTAAAAAAAAA 440
Query: 334 YSSVPFPEGEAFPPVSVTTLG 354
+ S+P P G A P S LG
Sbjct: 441 FPSLPPPPGSASLPPSGAPLG 461
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 48.9 bits (115), Expect = 7e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 209 EEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLG 268
+EA +NEN + L R+ RT+I+ + L+ F PKPT +AQ+ G
Sbjct: 164 KEAGSNEN-----DDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218
Query: 269 LEKDVVRVWFCNRRQKGKR 287
L V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 48.1 bits (113), Expect = 1e-05
Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 209 EEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLG 268
+E NNEN ++ + R+ RT+I+ + L+ F PKPT +AQ+ G
Sbjct: 164 KETANNENEEQNSGTK-----RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218
Query: 269 LEKDVVRVWFCNRRQKGKR 287
L V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 23/115 (20%)
Query: 245 LENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSP 304
LE F Q + + H+A L L V++WF NRR K KR D + E AG P
Sbjct: 65 LERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQD----KSLELAGHP 120
Query: 305 FSGGPVSFP---------LAPGPHFGTPGYGSPHFTAL--------YSSVPFPEG 342
+ V+ P L PGP G P + SP+ A+ YS P+ G
Sbjct: 121 LTPRRVAVPVLVRDGKPCLGPGP--GAPAFPSPYSAAVSPYSCYGGYSGAPYGAG 173
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 47.4 bits (111), Expect = 2e-05
Identities = 24/61 (39%), Positives = 33/61 (54%)
Query: 231 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 290
KR RT+I + L+N + PKP ++ + GL+ VV+VWF NRR K KR
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217
Query: 291 D 291
D
Sbjct: 218 D 218
>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
Length = 290
Score = 47.0 bits (110), Expect = 3e-05
Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Query: 231 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 290
KR RTS LE F +C ++ + +A+QL L + V+VWF NRR K K+ S
Sbjct: 103 KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQS 162
Query: 291 DYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVP-FPEGEAFPPVS 349
++ +A F+ + L G P +P AL S+P P
Sbjct: 163 RDLEKRASSSASEAFATSNILRLLEQGRLLSVP--RAPSLLALTPSLPGLPASH-----R 215
Query: 350 VTTLGSPMHSN 360
T+LG P +S+
Sbjct: 216 GTSLGDPRNSS 226
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 215 ENLQEICKA--ETLVQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQL 267
E+ + +CKA ET Q KR RT+I + L++ + PKP ++ +
Sbjct: 135 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 194
Query: 268 GLEKDVVRVWFCNRRQKGKRSSSD 291
GL+ VV+VWF NRR K KR D
Sbjct: 195 GLDMRVVQVWFQNRRAKEKRLKKD 218
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 215 ENLQEICKA--ETLVQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQL 267
E+ + +CKA ET Q KR RT+I + L++ + PKP ++ +
Sbjct: 140 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 199
Query: 268 GLEKDVVRVWFCNRRQKGKRSSSD 291
GL+ VV+VWF NRR K KR D
Sbjct: 200 GLDMRVVQVWFQNRRAKEKRLKKD 223
>gi|61969666 arginine-fifty homeobox [Homo sapiens]
Length = 315
Score = 46.6 bits (109), Expect = 3e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 223 AETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRR 282
A T ++ R ++RTS ++ LE LF Q P +A +L L + V+VWF NRR
Sbjct: 71 ATTAIRRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRR 130
Query: 283 QKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVP 338
K K+ + ++ + S P S +P P+ SP + YSS+P
Sbjct: 131 FKLKKQQQQQSAKQRNQILPSK-KNVPTSPRTSPSPY-----AFSPVISDFYSSLP 180
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 45.4 bits (106), Expect = 8e-05
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 18/112 (16%)
Query: 13 PPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIG-PGVGPGSEVWGIPPCPPPYEFCG 71
PPPG GG P P P T S PP PG G P + P PP PPP
Sbjct: 360 PPPGRGGPPPPPP------PATGRSGPLPPPPPGAGGPPMPP-------PPPPPPPPPSS 406
Query: 72 GMAYCGPQVGVGLVPQGGLETSQPEG----EAGVGVESNSDGASPEPCTVTP 119
G P + LVP GGL G + G++ N +PE + P
Sbjct: 407 GNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQP 458
>gi|11386181 H2.0-like homeobox [Homo sapiens]
Length = 488
Score = 45.4 bits (106), Expect = 8e-05
Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 224 ETLVQARKRKRT----SIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFC 279
+T+ Q KRKR+ N R LE F T +A LGL V+VWF
Sbjct: 266 DTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQ 325
Query: 280 NRRQKGKRSSSDYAQREDFEAAGSPFSGG 308
NRR K + S AQ++ + AG SGG
Sbjct: 326 NRRMKWRHSKEAQAQKDKDKEAGEKPSGG 354
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/85 (32%), Positives = 46/85 (54%)
Query: 203 LLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISH 262
L +K ++ DNN + +E + KR RT+I L +L PT + + H
Sbjct: 2533 LKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDH 2592
Query: 263 IAQQLGLEKDVVRVWFCNRRQKGKR 287
IA+++GL+K VV+VWF N R + ++
Sbjct: 2593 IAREVGLKKRVVQVWFQNTRARERK 2617
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/57 (38%), Positives = 31/57 (54%)
Query: 231 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
KR RT + N L+ F PT+Q+ + ++GL K VV+VWF N R K K+
Sbjct: 2885 KRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKK 2941
Score = 34.7 bits (78), Expect = 0.14
Identities = 20/71 (28%), Positives = 35/71 (49%)
Query: 229 ARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRS 288
+++ RT + L++ F P +I ++ L L V+ VWF N RQK ++S
Sbjct: 2180 SKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKS 2239
Query: 289 SSDYAQREDFE 299
+ A+ +D E
Sbjct: 2240 YENQAETKDNE 2250
Score = 31.6 bits (70), Expect = 1.2
Identities = 19/61 (31%), Positives = 31/61 (50%)
Query: 231 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 290
KR RT I + L F P+ +QI +A++ GL + V++ WF N K ++ +
Sbjct: 2085 KRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNK 2144
Query: 291 D 291
D
Sbjct: 2145 D 2145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,107,825
Number of Sequences: 37866
Number of extensions: 1417574
Number of successful extensions: 7604
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 273
Number of HSP's successfully gapped in prelim test: 390
Number of HSP's that attempted gapping in prelim test: 5401
Number of HSP's gapped (non-prelim): 2055
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.