Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 126362967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
(1909 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens] 3793 0.0
gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens] 707 0.0
gi|208022661 hypothetical protein LOC57701 [Homo sapiens] 122 4e-27
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 84 1e-15
gi|91982772 mucin 17 [Homo sapiens] 82 4e-15
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 73 3e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 73 3e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 73 3e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 73 3e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 70 2e-11
gi|31982906 cingulin-like 1 [Homo sapiens] 67 1e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 5e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 65 6e-10
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 64 1e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 63 2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 63 2e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 62 4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 4e-09
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 62 4e-09
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 62 4e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 4e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 62 7e-09
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 61 1e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 60 2e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 60 2e-08
gi|41281612 zinc finger protein 828 [Homo sapiens] 60 2e-08
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 60 3e-08
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 59 3e-08
gi|151301154 mucin 6, gastric [Homo sapiens] 59 5e-08
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 59 5e-08
>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
Length = 1909
Score = 3793 bits (9837), Expect = 0.0
Identities = 1909/1909 (100%), Positives = 1909/1909 (100%)
Query: 1 MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV 60
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV
Sbjct: 1 MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV 60
Query: 61 AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR 120
AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR
Sbjct: 61 AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR 120
Query: 121 NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE 180
NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE
Sbjct: 121 NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE 180
Query: 181 KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT 240
KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT
Sbjct: 181 KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT 240
Query: 241 RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA 300
RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA
Sbjct: 241 RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA 300
Query: 301 EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN 360
EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN
Sbjct: 301 EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN 360
Query: 361 LRKRQSSQNWDKRLSIDSSLPSGFASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSV 420
LRKRQSSQNWDKRLSIDSSLPSGFASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSV
Sbjct: 361 LRKRQSSQNWDKRLSIDSSLPSGFASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSV 420
Query: 421 ITKWGYKDCMNSNEGIYSPGIKSSSLKEYPPCKTADLGSPCKEPHKTFVYDLDSHVDADD 480
ITKWGYKDCMNSNEGIYSPGIKSSSLKEYPPCKTADLGSPCKEPHKTFVYDLDSHVDADD
Sbjct: 421 ITKWGYKDCMNSNEGIYSPGIKSSSLKEYPPCKTADLGSPCKEPHKTFVYDLDSHVDADD 480
Query: 481 DPSTLALLQAVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEKLTSC 540
DPSTLALLQAVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEKLTSC
Sbjct: 481 DPSTLALLQAVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEKLTSC 540
Query: 541 ASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESSDEKS 600
ASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESSDEKS
Sbjct: 541 ASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESSDEKS 600
Query: 601 PSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKR 660
PSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKR
Sbjct: 601 PSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKR 660
Query: 661 TSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACL 720
TSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACL
Sbjct: 661 TSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACL 720
Query: 721 QPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNI 780
QPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNI
Sbjct: 721 QPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNI 780
Query: 781 SCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALA 840
SCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALA
Sbjct: 781 SCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALA 840
Query: 841 PGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPA 900
PGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPA
Sbjct: 841 PGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPA 900
Query: 901 IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV 960
IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV
Sbjct: 901 IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV 960
Query: 961 PSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRC 1020
PSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRC
Sbjct: 961 PSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRC 1020
Query: 1021 PAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTS 1080
PAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTS
Sbjct: 1021 PAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTS 1080
Query: 1081 SKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK 1140
SKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK
Sbjct: 1081 SKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK 1140
Query: 1141 GLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME 1200
GLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME
Sbjct: 1141 GLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME 1200
Query: 1201 ITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKP 1260
ITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKP
Sbjct: 1201 ITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKP 1260
Query: 1261 HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE 1320
HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE
Sbjct: 1261 HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE 1320
Query: 1321 SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLL 1380
SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLL
Sbjct: 1321 SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLL 1380
Query: 1381 IPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETS 1440
IPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETS
Sbjct: 1381 IPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETS 1440
Query: 1441 STSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQ 1500
STSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQ
Sbjct: 1441 STSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQ 1500
Query: 1501 KPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPEL 1560
KPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPEL
Sbjct: 1501 KPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPEL 1560
Query: 1561 QCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTE 1620
QCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTE
Sbjct: 1561 QCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTE 1620
Query: 1621 LLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPK 1680
LLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPK
Sbjct: 1621 LLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPK 1680
Query: 1681 DSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLC 1740
DSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLC
Sbjct: 1681 DSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLC 1740
Query: 1741 QPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARG 1800
QPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARG
Sbjct: 1741 QPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARG 1800
Query: 1801 MRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQ 1860
MRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQ
Sbjct: 1801 MRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQ 1860
Query: 1861 DKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT 1909
DKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT
Sbjct: 1861 DKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT 1909
>gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens]
Length = 590
Score = 707 bits (1825), Expect = 0.0
Identities = 365/369 (98%), Positives = 365/369 (98%)
Query: 1 MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV 60
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV
Sbjct: 1 MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREV 60
Query: 61 AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR 120
AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR
Sbjct: 61 AQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVR 120
Query: 121 NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE 180
NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE
Sbjct: 121 NLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKE 180
Query: 181 KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT 240
KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT
Sbjct: 181 KTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKT 240
Query: 241 RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA 300
RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA
Sbjct: 241 RVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDA 300
Query: 301 EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN 360
EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN
Sbjct: 301 EVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKN 360
Query: 361 LRKRQSSQN 369
LRKR N
Sbjct: 361 LRKRVKEAN 369
Score = 454 bits (1167), Expect = e-127
Identities = 226/226 (100%), Positives = 226/226 (100%)
Query: 1684 VKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPD 1743
VKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPD
Sbjct: 365 VKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPD 424
Query: 1744 SPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRP 1803
SPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRP
Sbjct: 425 SPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRP 484
Query: 1804 LQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKA 1863
LQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKA
Sbjct: 485 LQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKA 544
Query: 1864 PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT 1909
PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT
Sbjct: 545 PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT 590
>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
Length = 1334
Score = 122 bits (305), Expect = 4e-27
Identities = 63/85 (74%), Positives = 71/85 (83%)
Query: 185 LLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFD 244
LL RL+ LEAENSALA NENQRE YERCLDEVAN VVQALL QKDLREEC+KLK RVFD
Sbjct: 33 LLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQALLNQKDLREECIKLKKRVFD 92
Query: 245 LEQQNRTLSILFQQRVRPTSDLLLQ 269
LE+QN+ LS LFQQ+++ T+ L Q
Sbjct: 93 LERQNQMLSALFQQKLQLTTGSLPQ 117
Score = 118 bits (296), Expect = 5e-26
Identities = 239/949 (25%), Positives = 337/949 (35%), Gaps = 187/949 (19%)
Query: 894 GSRSRPAIESSDSGEPPT--------RDEHCGSGPEA-----GVKSPSPPPPPGRSVSLL 940
G P SS PP + G PEA G S P P S+ +
Sbjct: 352 GDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMG 411
Query: 941 A-------RPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQR 993
A RP + +S + +K + PS + PLL +PA
Sbjct: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEA---QGPLLP---------SPARGLKFL 459
Query: 994 KKPSVAFKKPIFTHPMPSPEAVIQTRCPAH------APSSSFTVMALGPPKVSPK--RGV 1045
K P + K P P SP+ +R P +PS LG ++SP+ +G+
Sbjct: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGL 519
Query: 1046 PKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSAST------P 1099
P TSP TP L+ P+ + ST ++ VSP + L+ S ST
Sbjct: 520 P-TSPSPCYTTPD-STQLRPPQSALST----TLSPGPVVSPCYENILDLSRSTFRGPSPE 573
Query: 1100 PKPSFLGVNESPSSQVS---------SSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGL 1150
P PS L V P + S SP + P+G S EK L
Sbjct: 574 PPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG--SPQEKSLD------- 624
Query: 1151 KVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
K +SP R++ PG N + K S + + P + A + T
Sbjct: 625 KAGSESPHPGRRT---PG-------NSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTG 674
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVD-----NRSMRRSLSSSKPHLKPA 1265
P+ A GS +G+P ++ + PG G D +R + + + A
Sbjct: 675 PEG-ALGSEKNGVPARPGTEK---TRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVA 730
Query: 1266 LGMNGAKAR---------SHSFSTHS-GDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQ 1315
LG N K + + +S+HS G + P+ + T++ + +L Q
Sbjct: 731 LGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCL-TKVELAKSRLAGALCPQ 789
Query: 1316 NSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPK 1375
T P K P+ S PS+G+P+ P H SP+KLP + P K
Sbjct: 790 VPRT---PAKVPT-----SAPSLGKPNKSP----------------HSSPTKLPSKSPTK 825
Query: 1376 SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPS 1435
++P P A + P D+ PP DC G T S
Sbjct: 826 ----VVPR-------------PGAPLVTKESPKPDKGKGPPW-ADC-------GSTTAQS 860
Query: 1436 TFETSSTSKLETSGRHPDASATATDAVSSEAPLSP--TIEEKVMLCIQENVEKGQVQTKP 1493
T TD L+P IEEKVM I+ENV + Q Q +
Sbjct: 861 T----------------PLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERA 904
Query: 1494 TSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKK 1553
E K + S ASWFG +KS+LPAL+ R E K G L+ E K
Sbjct: 905 PGAEVKHRNTSSIASWFGLKKSKLPALNRR--------TEATKNKEGAGGGSPLRREVKM 956
Query: 1554 EKKKPELQCETENELI---KDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVA 1610
E +K E + ++L+ +D + A + S R P +A
Sbjct: 957 EARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLA 1016
Query: 1611 --CSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKK 1668
DTFM +LLNRVD K P + SS S G
Sbjct: 1017 GMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPK----SPWPACGPRNG 1072
Query: 1669 NMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLP 1728
+ P E + +D++A+ V SH RTLDSGIGTFP P
Sbjct: 1073 LVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPP 1132
Query: 1729 DSGNRSTGRYLCQPDSPEDAEP---LLPLQSALSAVSSMRAQTLEREVP 1774
D G+ T P +P + P + RA TLEREVP
Sbjct: 1133 DHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVP 1181
Score = 48.5 bits (114), Expect = 6e-05
Identities = 109/485 (22%), Positives = 168/485 (34%), Gaps = 70/485 (14%)
Query: 836 SPALAPGKL----SRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQ 891
SP A G L +R +K P E P P+ S QLP +SR+P R S
Sbjct: 440 SPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSP 499
Query: 892 TPGSRSRPAIESSDSGEP--PTRDEHCGSGPEAGVKSP---------SPPP---PPGRSV 937
R E S G PT C + P++ P SP P P ++
Sbjct: 500 LLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
Query: 938 SLLARPSYDYSPAPSSTKSETRVPSE---TARTPFKSPLLKGISAPVISSNP-------- 986
L+R ++ P+P S +VP+ T P +L+ P P
Sbjct: 560 LDLSRSTF-RGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSP 618
Query: 987 ---ATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP-- 1041
+ + + P + P + PS + + P P + ALG K P
Sbjct: 619 QEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRD-RLAALGKLKTGPEG 677
Query: 1042 -----KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSA 1096
K GVP + P + G + PS H PLE +K G L ++
Sbjct: 678 ALGSEKNGVPARPGTEKTRGPGKS-GESAGDMVPSIHRPLEQLEAKGGIRGAVA-LGTNS 735
Query: 1097 STPPKPSFLGVNESPSSQVSSSSSSSSPAKSHN-SPHGCQSAHEKGLKTRLPVGL----- 1150
+P +G P ++V SS S + SP C + E K+RL L
Sbjct: 736 LKQQEPGLMG---DPGARVYSSHSMGARVDLEPVSPRSCLTKVELA-KSRLAGALCPQVP 791
Query: 1151 ----KVLMKSPQLLRKSST-------VPGKHEKDSLNEASKSSVAVNKSKPEDSKNP--A 1197
KV +P L + + + +P K + V KP+ K P A
Sbjct: 792 RTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWA 851
Query: 1198 SMEITAGERNVTLP----DSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRR 1253
T + +P SQ LA +E + + +E ++ G++ ++
Sbjct: 852 DCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKH 911
Query: 1254 SLSSS 1258
+SS
Sbjct: 912 RNTSS 916
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 84.0 bits (206), Expect = 1e-15
Identities = 250/1158 (21%), Positives = 400/1158 (34%), Gaps = 198/1158 (17%)
Query: 777 THNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKS 836
+H+ + Q RS + K ++ R SSP+ K + + S +L
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK-------SRISSRRSRSLSSP 765
Query: 837 PALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLP-HSSRMPSRRDWVQCPKSQTPGS 895
+ A +LS S P PK +Q P SR S + KS+TP
Sbjct: 766 RSKAKSRLSLRRSLSGSSPC---------PKQKSQTPPRRSRSGSSQPKA---KSRTPPR 813
Query: 896 RSRPAIES--SDSGEPPTRDEHCGSGPEAGVKSPSPPPPPG--------RSVSLLARPSY 945
RSR + + P+R H S P VKS +PP +SV+ R +
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCF 873
Query: 946 DYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIF 1005
+ SP P + ++R PS + + P +K + P R+ PS +
Sbjct: 874 ESSPDP---ELKSRTPSRHSCSGSSPPRVKSSTPP------------RQSPSRS------ 912
Query: 1006 THPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLG-TPQRDI--- 1061
+ P P +A+I R +H+ SSS SP R +T+PR++ +P ++
Sbjct: 913 SSPQPKVKAIISPRQRSHSGSSS----------PSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 1062 --------GLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSS 1113
G +P P + S S+SP K + A TPP PS G ++SP
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK----AQTPPGPSLSG-SKSPCP 1017
Query: 1114 QVSSSSS--SSSPA--------KSHNSP----HGCQSAHEKGLK---------TRLPVGL 1150
Q S S S P KS P G S KG T P
Sbjct: 1018 QEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVR 1077
Query: 1151 KVLMKSPQLLRKSSTVP--GKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNV 1208
+ +SP L KS T P G+ S S + + + E S +P + E++
Sbjct: 1078 QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSR 1137
Query: 1209 TLPDSQA-----QGSLADGLPLETALQEPLESSIPGSDG----------------RDGVD 1247
DS + SL LETA + + P D +D +
Sbjct: 1138 FQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE 1197
Query: 1248 NRSMRRSLSSSKPHLKPALGMNG-AKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTA 1306
+ + + + P + G + K ++ + T S D+ +E S + QI+++ +
Sbjct: 1198 SSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLS 1257
Query: 1307 ERGNSLTRQN--SSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGS 1364
++ N SS E A S + +S + S S G FS +H
Sbjct: 1258 SELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGP-HFSPEHKE 1316
Query: 1365 PSKLPLRIPPKSEGLLI----PPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD 1420
S PLR L P G E F+ N L + +D D
Sbjct: 1317 LSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETD------PSLD 1370
Query: 1421 CPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCI 1480
E QS + H S+ + + + S+ DAV P +P+ E
Sbjct: 1371 MKE--QSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV----PRTPSRERSSSASS 1424
Query: 1481 QENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKK---DA 1537
E ++ G +T + PG S R S L S DI +T + D+
Sbjct: 1425 PE-MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHS-LSGSSPGMKDIPRTPSRGRSECDS 1482
Query: 1538 KVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTP------ 1591
Q R + PEL N+ + + + + K RTP
Sbjct: 1483 SPEPKALPQTPRPRSRSPSSPELN----NKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
Query: 1592 ----QDIYNQLKIEPRNR-HSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVL 1646
Q++ + P+ R S + +K T L R ++P+ +S S S R
Sbjct: 1539 SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS-KSRLSPRRSR 1597
Query: 1647 KGSS---QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSV 1703
GSS + + + K A +P+ S +++ + + +
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 1704 FQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSS 1763
H +S RT G + P P + +R+ R SPE
Sbjct: 1658 SPEHPPKS----RTARRGSRSSPEPKTKSRTPPRRRSSRSSPE----------------- 1696
Query: 1764 MRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN 1823
L R+ S + + S S + P R R P+PA + S ++++
Sbjct: 1697 -----LTRKARLSRRSRSASSSPETRSRTPP----RHRRSPSVSSPEPAEKSRSSRRRRS 1747
Query: 1824 EAEPRPQTCSSFGYAEDP 1841
+ PR +T S G + P
Sbjct: 1748 ASSPRTKTTSRRGRSPSP 1765
Score = 72.0 bits (175), Expect = 5e-12
Identities = 190/801 (23%), Positives = 288/801 (35%), Gaps = 119/801 (14%)
Query: 818 EPEATTLL-------PSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSA 870
+P ATT L PS T ++SP +P KL + +ESS P + +H++
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP---SPQPTKVSRHAS 435
Query: 871 QLPHSSRMP----SRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKS 926
P S + S R+ P S+ S R + S S P R S A
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKN-RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
Query: 927 PSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNP 986
P R S P + S + + +R P R+ +SP G S
Sbjct: 495 SRSRTPTKRGHSRSRSPQWRRSRS-AQRWGRSRSPQRRGRS--RSPQRPGWS-------- 543
Query: 987 ATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVP 1046
+ QR+ S + ++ P+ ++R PA S P R
Sbjct: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT-----PARRRSRSRT 598
Query: 1047 KTSPRQTLGTPQR--DIGLQTP-RISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPS 1103
T R TP R +TP R T P+ S+S SP R+ + S + P+
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRT----PA 653
Query: 1104 FLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKS 1163
G + S + S S +PA+ A ++R P + +S L+R+
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTP--RRGRSRSRSLVRRG 711
Query: 1164 ---STVPGKHEK--DSLNEASKSSVAVNKSKPEDSKNPASMEITA-GERNVTLPDSQAQG 1217
S P + + S +KS + +S+ S I++ R+++ P S+A+
Sbjct: 712 RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771
Query: 1218 ------SLADGLPL-ETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
SL+ P + Q P S GS RRS SSS P P
Sbjct: 772 RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP--PPKQKSKT 829
Query: 1271 AKARSHSFST-HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSST-ESSPNKAPS 1328
+SHS S+ H K TPP +GS IT+ S+T Q S ESSP+
Sbjct: 830 PSRQSHSSSSPHPKVKSGTPPRQGS-------ITSPQANEQSVTPQRRSCFESSPD---- 878
Query: 1329 APMLESLPSVGRPSGHPSSGKG-SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKED 1387
P L+S PS H SG S + Q S S P PK + ++ P
Sbjct: 879 -PELKS----RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP---QPKVKAIISP----R 926
Query: 1388 QQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLET 1447
Q++ + PS + + RRS +P E+ P R H + + K ET
Sbjct: 927 QRSHSGSSSPSPSRVT--SRTTPRRSRSVSPCSNVESRLLP-RYSHSGSSSPDTKVKPET 983
Query: 1448 SGRHP-DASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTS------VEAKQ 1500
R S + V ++ P P++ C QE + VQ+ P S V++
Sbjct: 984 PPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSST 1043
Query: 1501 KPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPEL 1560
PG S+ FG +L G Q + + + PE+
Sbjct: 1044 PPGESY---FGVSSLQLK------------------------GQSQTSPDHRSDTSSPEV 1076
Query: 1561 QCETENELIKDTKSADNPDGG 1581
+ +KS +P GG
Sbjct: 1077 RQSHSESPSLQSKSQTSPKGG 1097
Score = 67.0 bits (162), Expect = 2e-10
Identities = 215/1001 (21%), Positives = 342/1001 (34%), Gaps = 117/1001 (11%)
Query: 876 SRMPSRRDWVQCPKSQTPGSRSR-----PAIESSDSGEPPTRDEHCGSGPEAG-VKSPSP 929
SR P+ R +S+TP R R PA S S P R + G +S +P
Sbjct: 564 SRSPATRGR---SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 930 PPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGIS---APVISSNP 986
R+ S + R S SPA S +S +R P+ R+ ++P +G S P S
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680
Query: 987 ATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQ-----TRCPAHAPSSSFTVMALGPPKVSP 1041
+ + ++ + P ++++ +R P S + + S
Sbjct: 681 SRSRTPARRGRSRSRTP--RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738
Query: 1042 KRGVPKTSP--RQTLGTPQRDIGLQTPRISPSTHEPLEMT-SSKSVSPGRKGQLNDSAST 1098
+R +SP +++ + +R L +PR + L + S S P +K Q T
Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ------T 792
Query: 1099 PPKPSFLGVNESPSS-----QVSSSSSSSSPAKSHNSP----HGCQSAHEKGLKTRLPVG 1149
PP+ S G ++ + + S SSSS P + +P H S H K +K+ P
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK-VKSGTP-P 850
Query: 1150 LKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVT 1209
+ + SPQ +S T + +S + S ++ S P T
Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST------- 903
Query: 1210 LPDSQAQGSLADGLPLETALQEPLESSIPGSD--GRDGVDNRSMRRSLSSSKPHLKPALG 1267
P Q+ + P A+ P + S GS V +R+ R S P
Sbjct: 904 -PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 1268 MNGAKARSHSFSTHSGDKPSTPP-------IEGSGKVRTQIITNTAERGN-SLTRQNSST 1319
+ + S S S + KP TPP I KV+ Q + G+ S Q S
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022
Query: 1320 ESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSG--SFSSQHGSPSKLPLRIPPKSE 1377
+S P + L + P G G SL G S H S + P
Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSP-------- 1074
Query: 1378 GLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTF 1437
E +Q+ ++ + + G R S P T A +SP R Q F
Sbjct: 1075 --------EVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL----ASRSPIR-QDRGEF 1121
Query: 1438 ETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVML--CIQENVEKGQVQTKPTS 1495
S S + SG P+ S +D+ S PT++ +L E E + P
Sbjct: 1122 ---SASPMLKSGMSPEQSRFQSDSSS-----YPTVDSNSLLGQSRLETAESKEKMALPPQ 1173
Query: 1496 VEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEK 1555
+A P + F P S D +T ++ G G+ S KE+
Sbjct: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERS----GAGS----SPETKEQ 1225
Query: 1556 KKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKD 1615
+ EL++ + ++ P G + S + + + + P P T D
Sbjct: 1226 NSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLD 1285
Query: 1616 TFMTEL-LNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKA 1674
++ L V+ + + G + L S GS + + + +
Sbjct: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPL----EFRNSGPLGT 1341
Query: 1675 DMEVPKDSLVKEANEN--LQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGN 1732
+M S VKE L + E D D QS T SG + L
Sbjct: 1342 EMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS----------TRSSGHSSSELSPDAV 1391
Query: 1733 RSTGRYLCQPDSPE--DAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHS 1790
G Q S DA P P + S+ SS + PS + S
Sbjct: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451
Query: 1791 TSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQT 1831
+ + G P +P+ S G+ E + PQT
Sbjct: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
Score = 64.7 bits (156), Expect = 8e-10
Identities = 146/631 (23%), Positives = 225/631 (35%), Gaps = 99/631 (15%)
Query: 808 KSSPQKSKLMEPEATTLLPSSGLVTLEKSPAL--APGKLSRFMKTESSGPLFELRSDPHI 865
+SS S + P+A S ++ SP L P SR + +S P E++ +
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSIS-SPVLDAVPRTPSRERSSSASSP--EMKDG--L 1431
Query: 866 PKHSAQLPHSSRMPSRRDWVQCPK-----SQTPGSRSRPAIESSDSGEPPTRDEHCGSGP 920
P+ ++ S P RD P +PG + P S E C S P
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE-------CDSSP 1484
Query: 921 EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSET-ARTPFKSPLLKGISA 979
E P P P RS S + +P + SE+ V +T ARTP G S+
Sbjct: 1485 EPKAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSG-SS 1542
Query: 980 PVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKV 1039
+ P+ + +R + SP++ +TR P S S + P+V
Sbjct: 1543 QELDVKPSASPQERSESD------------SSPDSKAKTRTPLRQRSRSGS-----SPEV 1585
Query: 1040 SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSS-KSVSPGRKGQLNDSAST 1098
K + SPR++ ++ PR +P + + K+ +P + + S S
Sbjct: 1586 DSKS---RLSPRRSRSGSSPEVK-DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS- 1640
Query: 1099 PPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQ 1158
S G SP S+ SS P KS + G +S+ E K+R P + SP+
Sbjct: 1641 ----SSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696
Query: 1159 LLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGS 1218
L RK+ L+ S+S+ S PE R+ T P + S
Sbjct: 1697 LTRKA----------RLSRRSRSA----SSSPE-------------TRSRTPPRHRRSPS 1729
Query: 1219 LADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSF 1278
++ EP E S R R+ S P KP G+ +++RS
Sbjct: 1730 VSS--------PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR-GLQRSRSRSRRE 1780
Query: 1279 ST-------HSGDKPSTPPIEGSGKVRTQIIT----NTAERGNSLTRQNSSTESSPNKAP 1327
T SG ST + R+++ + S RQ SS SS +
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 1328 SAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKED 1387
+ + R P+ K S S S ++ S S+ PL +S P +
Sbjct: 1841 RSRTPPTSRKRSRSRTSPAPWKRS-RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 1388 QQAFTQGECPSANVAVLGEPGSDRRSCPPTP 1418
++ T P S RRS TP
Sbjct: 1900 SRSRT--SVTRRRSRSRASPVSRRRSRSRTP 1928
Score = 56.6 bits (135), Expect = 2e-07
Identities = 159/703 (22%), Positives = 243/703 (34%), Gaps = 139/703 (19%)
Query: 788 SSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPE------ATTLLPSSGLVTLEKSPAL-A 840
S PM + Q+ + + G P + PE L + L T P++ A
Sbjct: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
Query: 841 PGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDW-VQCPKSQTPGSRSRP 899
G +R + + PL LR+ P +A L +SR+P+ + ++TP +
Sbjct: 2202 AGLAARMSQVPAPVPLMSLRTAP-----AANL--ASRIPAASAAAMNLASARTPAIPT-- 2252
Query: 900 AIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETR 959
A+ +DS P A + SP S LA P +PA
Sbjct: 2253 AVNLADSRTPAAA---------AAMNLASPRTAVAPSAVNLADPRTPTAPA--------- 2294
Query: 960 VPSETARTP--FKSPLLKGISAPVISSN-PATTEVQRKKPSVAFKKPIFTHPMPSPEAVI 1016
V ARTP + L G P ++N P+++ + S P H +P +
Sbjct: 2295 VNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT-APVNIA 2353
Query: 1017 QTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTP--------RI 1068
+R A +S T + P G TSPR L +R G +P R
Sbjct: 2354 GSRTAAALAPASLTSARMAPAL----SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRT 2409
Query: 1069 SPSTHEPLEMTSSKSVSPG-RKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKS 1127
PS MTS ++ SP R GQ + PP + P S V S+ S S
Sbjct: 2410 PPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP------AQDQPRSPVPSAFSDQSRC-- 2461
Query: 1128 HNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNK 1187
L+ +++ V G S SS AV
Sbjct: 2462 -------------------------------LIAQTTPVAGSQ--------SLSSGAV-- 2480
Query: 1188 SKPEDSKNPASMEITAGERN--VTLPDSQAQGSLADGLPLETALQEP--LESSIPGSDGR 1243
A+ +AG+ N +++P S P T Q+P L + P + R
Sbjct: 2481 ---------ATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531
Query: 1244 DGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIIT 1303
+ S S SSS + + + S S S+ S + S+ P++ +V + +
Sbjct: 2532 SSSSSSSSSSSSSSSS---------SSSSSSSSSGSSSSDSEGSSLPVQP--EVALKRVP 2580
Query: 1304 NTAERGNSLTRQNSSTESSPNK---------APSAPMLESLPSVGRPSGHPSSGKGSLGS 1354
+ R+ E +P K + S+ S S S SS S S
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1355 SGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSA--NVAVLGEPGSDRR 1412
S S SS SP+K + PK PP E + + S + ++ P RR
Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700
Query: 1413 SCP-PTPTDCPEALQSPG--RTQHPSTFETSSTSKLETSGRHP 1452
P P+P D + G R Q + S + ET P
Sbjct: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 53.9 bits (128), Expect = 1e-06
Identities = 229/1084 (21%), Positives = 364/1084 (33%), Gaps = 170/1084 (15%)
Query: 862 DPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPE 921
+P P + SSR P+ + + K + G RS + + + + +H
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKK-KKKKDRGRRSESSSPRRERKKSSKKKKHRSESES 224
Query: 922 AGVKSPSPPPPPGR-SVSLLARPSYDYSPAPSS------TKSETRVPSETARTPFKSPLL 974
K SP P R S + S +PAP S T +++ S+T+R+ +S
Sbjct: 225 KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
Query: 975 KGISAPVISSNPATTEVQRKKPSVAFKKP--IFTHPMPSPE-AVIQTRCPAHAPSSSFTV 1031
K + + +P+ +R + F +P T SPE A Q P
Sbjct: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
Query: 1032 MALGPPKVSPKRGVPKTSPRQTLGTP---QRDIGLQTP-RISPSTHEPLEMTSSKSV--- 1084
+ P SP+R T P TP +R G P +P + EP+ S S
Sbjct: 345 KSATRPSPSPERS--STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD 402
Query: 1085 -----SPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHE 1139
SP + Q + S S+PP P V S SSS S PA +
Sbjct: 403 RSPPKSPEKLPQSSSSESSPPSPQPTKV----SRHASSSPESPKPAPA------------ 446
Query: 1140 KGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASM 1199
P + + SP +S G+ ++D + + S P +K S
Sbjct: 447 -------PGSHREISSSPTSKNRSH---GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSR 496
Query: 1200 EITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSK 1259
T +R G P + S R G R S S+
Sbjct: 497 SRTPTKR----------GHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546
Query: 1260 PHLKPALGMNGAKARSHSFS--THSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNS 1317
+ + + RSHS S T + TP G + RT + R + R S
Sbjct: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606
Query: 1318 STES----SPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHG-SPSKLPL-- 1370
T + S ++ P+ + V R S S + S S ++ G S S+ P
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
Query: 1371 -----RIPPKSEG-----LLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD 1420
R P + G G+ + +G S ++ G RS TP
Sbjct: 667 GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG------RSHSRTP-- 718
Query: 1421 CPEALQSPGRTQHPSTFETSS--TSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVML 1478
Q GR+ S + S + + S P+ + + S + SP + K L
Sbjct: 719 -----QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL 773
Query: 1479 CIQENVE------KGQVQTKP-------TSVEAKQKPGP----SFASWFGFRKSRLPALS 1521
++ ++ K + QT P + +AK + P S +S +KS+ P+
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833
Query: 1522 SRKMDISKTKVEKKDAKVLG-FGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDG 1580
S KV+ G + Q + +++ + + EL T S + G
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893
Query: 1581 G-----------LQSKNNRRTPQDIYNQLKIEPRNR-HSPVACSTKDTFMTELLNRVDKK 1628
QS + +PQ + I PR R HS + + + R +
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAI-ISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 1629 AAPQTESGSSNASCRNVLKGSSQGSCLIGSSI--------STQGNHKKNMKIKADMEVPK 1680
+P SN R + + S GS + + S G+ K+KA P
Sbjct: 953 VSP-----CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP-PG 1006
Query: 1681 DSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTL--DSGIGTFPLPDSGNRSTGRY 1738
SL + QE D++ S S + + + T +S G L G T
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT--- 1063
Query: 1739 LCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVH--STSDPI- 1795
PD D S S + +L+ + +S G R S+ V ++ PI
Sbjct: 1064 --SPDHRSDT------SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIR 1115
Query: 1796 ----------MTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQ 1845
M GM P QSR +SS + R +T S ++ MA
Sbjct: 1116 QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAES----KEKMALP 1171
Query: 1846 PLPD 1849
P D
Sbjct: 1172 PQED 1175
Score = 53.5 bits (127), Expect = 2e-06
Identities = 172/830 (20%), Positives = 289/830 (34%), Gaps = 141/830 (16%)
Query: 690 TVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEKNIPKDNVD 749
+VTR ++P + + P + R+ +R T +RS T + +
Sbjct: 1905 SVTRRRSRSRASPVSRRRSRSRTPP----VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRS 1960
Query: 750 NVPRVSTESFSSRT--VTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRG 807
P V+ SRT +T+ + + T +S SR+S +T+ R
Sbjct: 1961 RTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR---RSRSRTSP---------VTRRRSRS 2008
Query: 808 KSSP---QKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPH 864
++SP ++S+ P A S ++P L P K SR S PL R
Sbjct: 2009 RTSPVTRRRSRSRTPPAIRRRSRS------RTPLL-PRKRSR-----SRSPLAIRR---- 2052
Query: 865 IPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGV 924
+ ++ P ++R +R + P + S S + + S S PP H GS
Sbjct: 2053 --RSRSRTPRTAR--GKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR----- 2103
Query: 925 KSPSPPPPPGRS-VSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVIS 983
+PP S +S +RPS +P P ++RTP S L + + +
Sbjct: 2104 ---TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPM-SVLQQAGGSMMDG 2159
Query: 984 SNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKR 1043
P + QR PE Q+R + + T ++LG + P
Sbjct: 2160 PGPRIPDHQRTSV---------------PENHAQSRI-----ALALTAISLGTARPPPSM 2199
Query: 1044 G----------VPKTSPRQTLGT-PQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQL 1092
VP P +L T P ++ + P S + M + + +P +
Sbjct: 2200 SAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAA-----MNLASARTPAIPTAV 2254
Query: 1093 NDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKV 1152
N + S P + SP + V+ S+ + + ++ +P + + G +T P L
Sbjct: 2255 NLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAP----AVNLAGART--PAALAA 2308
Query: 1153 LMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL-P 1211
L L S T P S + ++ + N P + A + I L P
Sbjct: 2309 LS-----LTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAP 2363
Query: 1212 DSQAQGSLADGLPLE--TALQEPLES--SIPGSDGRDGVDNRSMRR-----SLSSSKPHL 1262
S +A L T+ + PL + + G +D R S S
Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423
Query: 1263 KPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESS 1322
P+ +A S S + D+P +P +I T S + + + ++
Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATT 2483
Query: 1323 PNKAPSAPMLESLPSVGRPS---GHP-----------------------SSGKGSLGSSG 1356
+ A + S+P+ G P G P SS S SS
Sbjct: 2484 TSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSS 2543
Query: 1357 SFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPP 1416
S SS S S SEG +P E P+ AV R PP
Sbjct: 2544 SSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV-------REGRPP 2596
Query: 1417 TPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEA 1466
PT +S + S+ +SS+S +S +S++++ + SS +
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Score = 50.8 bits (120), Expect = 1e-05
Identities = 104/461 (22%), Positives = 174/461 (37%), Gaps = 67/461 (14%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSP 811
P + SSRT Q P LV P ++ ++AP+ I + + P +S
Sbjct: 2318 PTAANYPSSSRT-PQAPASANLVGPR-------SAHATAPVNIAGSRTAAALAPASLTSA 2369
Query: 812 QKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQ 871
+ + + S +T + P A ++S +S PL + R+ P +
Sbjct: 2370 RMAPAL---------SGANLTSPRVPLSAYERVSG----RTSPPLLD-RARSRTPPSA-- 2413
Query: 872 LPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPP 931
P SRM S R P SR S S PP +D+ +SP P
Sbjct: 2414 -PSQSRMTSER---------APSPSSRMGQAPSQSLLPPAQDQP---------RSPVPSA 2454
Query: 932 PPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLK----GISAPVISSNPA 987
+S L+A+ + A S + S V + T+ + +L G+ + PA
Sbjct: 2455 FSDQSRCLIAQTT---PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA 2511
Query: 988 TTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPK 1047
+T Q+ A + P+ E R + + SSS + + S
Sbjct: 2512 STGAQQPSALAALQ--------PAKER----RSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Query: 1048 TSPRQTLGTP-QRDIGLQ-TPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFL 1105
+S + P Q ++ L+ P +P+ E + +P ++ + + S+S+ S
Sbjct: 2560 SSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619
Query: 1106 GVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSST 1165
+ S SS SSSSSSSS + S +S S + G + LP K P + S
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-LP--KPASPKKPPPGERRSR 2676
Query: 1166 VPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGER 1206
P K + S S V + +P +P + ++ ER
Sbjct: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717
Score = 45.4 bits (106), Expect = 5e-04
Identities = 88/395 (22%), Positives = 138/395 (34%), Gaps = 47/395 (11%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSP 811
PRV ++ + +P + S S SR ++ + + P + P
Sbjct: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442
Query: 812 QKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSR---FMKTESSGPLFELRS--DPHIP 866
+ + P + S + + +P LS T S+G + S P +P
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 867 KHSAQLPHSS---RMPS----------RRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRD 913
P +S + PS RR S + S S + SS S + D
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 914 EHCGS---GPEAGVKS-PSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPF 969
S PE +K PSP P P +V RP P P+ K + R S ++ +
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVRE-GRP-----PEPTPAKRKRRSSSSSSSSSS 2616
Query: 970 KSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSF 1029
S S+ SS+ +++ S + + P P+A+ + P P
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP---SPAKPGPQALPKPASPKKPPPGER 2673
Query: 1030 TVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRK 1089
SP++ P S R + + + P PS P + SS S R+
Sbjct: 2674 RSR-------SPRK--PIDSLRDSRSLSYSPVERRRPSPQPS---PRDQQSSSSERGSRR 2721
Query: 1090 GQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSP 1124
GQ DS S PS E+PS + SS SP
Sbjct: 2722 GQRGDSRS----PSHKRRRETPSPRPMRHRSSRSP 2752
Score = 44.7 bits (104), Expect = 9e-04
Identities = 236/1170 (20%), Positives = 402/1170 (34%), Gaps = 156/1170 (13%)
Query: 500 GSKLTHSVSDSLFGWE----TNRKHFLEGTSSVYPKERPEKLTSCASSCPLEMKLCPSVQ 555
G+ HS+S S G + T + E SS PK P+ + S P +L
Sbjct: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS-PSSPELNNKCL 1510
Query: 556 TPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESS---DEKSPSDVSLAADTDK 612
TPQ +R G + + L + + EL ++ S E+S SD S D
Sbjct: 1511 TPQRERS-GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS----PDS 1565
Query: 613 SVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQ-RVVKRTSSEECVTVIF 671
+ L +S SPE + K P +R + +K + R R S
Sbjct: 1566 KAKTRTPLRQRSRS-GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS-------- 1616
Query: 672 DAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPK-AEHTELLPQGIACLQP-RAAARDY 729
D P + + +R+ S P+ + TE P+ + R +R
Sbjct: 1617 -GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 730 TFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSS 789
K + + + R + S SR+ + +P+ + P H S +S
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
Query: 790 APMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPAL---------- 839
A ++ + PR K++ ++ + P+ L S EK+
Sbjct: 1736 AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795
Query: 840 -------APGKLSRFMKTESSGPLFELRS---------DPHIPKHSAQLPHSSRMPSRRD 883
SR + G + RS + ++ P +SR SR
Sbjct: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
Query: 884 WVQCP----------------KSQTP-----GSRSRPAIESSDSGEPPT----RDEHCGS 918
P +S+TP SRSR + S T R +
Sbjct: 1856 TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
Query: 919 GPEAGVKSPSPPPPPGRSVSLLARP-----SYDYSPAPSSTKSETRVPSETARTPFK--S 971
P + +S S PP R S P S +P + +S +R P T R S
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTS 1975
Query: 972 PLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTV 1031
P+ + S ++P T R + S ++ + P ++R P S +
Sbjct: 1976 PITRRRSRS--RTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSR 2033
Query: 1032 MALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPST---HEPLEMTSSKSVSPGR 1088
L P K S R R TP+ G ++ SP +S +S S
Sbjct: 2034 TPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093
Query: 1089 KGQLNDSAS-TPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLP 1147
N S S TPP + +N S S S S S +P SP + +T +
Sbjct: 2094 PATRNHSGSRTPP----VALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS--RTPMS 2147
Query: 1148 V-----GLKVLMKSPQLL-RKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEI 1201
V G + P++ + ++VP H + + + +++++ ++P S + A +
Sbjct: 2148 VLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRI-ALALTAISLGTARPPPSMSAAGLAA 2206
Query: 1202 TAGERNVTLP------------DSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNR 1249
+ +P S+ + A + L +A + +++ +D R
Sbjct: 2207 RMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAA 2266
Query: 1250 SMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERG 1309
+M +L+S + + P+ +N A R+ P+ P + +G RT
Sbjct: 2267 AM--NLASPRTAVAPS-AVNLADPRT----------PTAPAVNLAG-ARTPAALAALSLT 2312
Query: 1310 NSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGS-------SGSFSSQH 1362
S T ++ S ++ P AP +L VG S H ++ GS S +S
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANL--VGPRSAHATAPVNIAGSRTAAALAPASLTSAR 2370
Query: 1363 GSPS---------KLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSAN--VAVLGEPGSDR 1411
+P+ ++PL + G PP + ++ T PS + + S R
Sbjct: 2371 MAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSR 2430
Query: 1412 RSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPT 1471
P+ + P A P R+ PS F S S+ + P A + + + + S
Sbjct: 2431 MGQAPSQSLLPPAQDQP-RSPVPSAF--SDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
Query: 1472 IEEKVMLCI-QENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKT 1530
+ ML + V V P S A+Q PS + K R + SS S +
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPASTGAQQ---PSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 1531 KVEKKDAKVLGFGNRQLKSERKKEKKKPEL 1560
+ G+ SE +PE+
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574
Score = 42.0 bits (97), Expect = 0.006
Identities = 209/1032 (20%), Positives = 347/1032 (33%), Gaps = 177/1032 (17%)
Query: 925 KSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISS 984
K P+P PP + SL+ S SP P K + + R+ SP + +
Sbjct: 161 KQPAPEPP--KPYSLVRESSSSRSPTPKQKKKKKK-KDRGRRSESSSPRRERKKSSKKKK 217
Query: 985 NPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRG 1044
+ + +E +++K H P+P++ +++ S S T P +R
Sbjct: 218 HRSESESKKRK-----------HRSPTPKSKRKSKDKKRKRSRSTT------PAPKSRRA 260
Query: 1045 VPKTSPRQTLGTPQRDIGLQTPR-ISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPS 1103
TS + D R + TH S S + GR+G+ + S P S
Sbjct: 261 HRSTSADSASSS---DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTS 317
Query: 1104 FLGVNESPSSQVSSSSSSSSP---------AKSHNSPHGCQSAHEKGLKTRLPVGLKVLM 1154
+ PSS +++ SSP KS P G + P L
Sbjct: 318 ----TQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
Query: 1155 K--SPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASM-EITAGERNVTLP 1211
SPQ L +T P E +N S++S ++S P K+P + + ++ E + P
Sbjct: 374 HGGSPQPL---ATTPLSQE--PVNPPSEASPTRDRSPP---KSPEKLPQSSSSESSPPSP 425
Query: 1212 DSQAQGSLADGLPLETALQEPLESSIPGS----DGRDGVDNRSMRRSLSSSKPHLKPALG 1267
A P + P + PGS NRS R+ P+
Sbjct: 426 QPTKVSRHASSSP-----ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
Query: 1268 MNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQ--IITNTAERGNSLTRQNSSTESSPNK 1325
M ++RS + + + TP G + R+ + +A+R R S ++
Sbjct: 481 M--GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWG---RSRSPQRRGRSR 535
Query: 1326 APSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGK 1385
+P P + R G S + S S +++ S S+ P R + P +
Sbjct: 536 SPQRPGWSRSRNTQR-RGRSRSARRGRSHSRSPATRGRSRSRTPAR---RGRSRSRTPAR 591
Query: 1386 EDQQAFT------QGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFET 1439
++ T + P+ + RRS +P +SP R S T
Sbjct: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
Query: 1440 SS---TSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQ-----ENVEKGQVQT 1491
+ S+ T R S + T A S S T + + + + V+
Sbjct: 652 PARRGRSRSRTPARR-GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710
Query: 1492 KPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSER 1551
+ Q+ G S +S KSR +S++ S + E K +++ +R L S R
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSR----TSQRRSRSNSSPEMKKSRISSRRSRSLSSPR 766
Query: 1552 KKEKKKPELQCETENELIKDTKSADNP-----DGGLQSKNNRRTPQDIYNQLKIEPRNRH 1606
K K + L+ + + P G Q K RTP PR
Sbjct: 767 SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP----------PRRSR 816
Query: 1607 SPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNH 1666
S + K K P +S SS++ V G+ GS S Q N
Sbjct: 817 SSSSPPPK-----------QKSKTPSRQSHSSSSPHPKVKSGTPPRQ---GSITSPQAN- 861
Query: 1667 KKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFP 1726
E S F+S P
Sbjct: 862 --------------------------EQSVTPQRRSCFESS------------------P 877
Query: 1727 LPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQT---LEREVPSSTDGQRPA 1783
P+ +R+ R+ C SP + P + + S SS + + + S + P+
Sbjct: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
Query: 1784 DSAIVHSTSDPIMTARGMRP---LQSR-LPKPASSGKVSSQKQNEAEPRPQTCSSFGYAE 1839
S + T+ +R + P ++SR LP+ + SG S + + E P+ S +
Sbjct: 938 PSRVTSRTTP--RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995
Query: 1840 DPMASQPLPDWGSEVAATG------TQDKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRG 1893
P P S + ++D + C S S + S G++ FG
Sbjct: 996 YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL 1055
Query: 1894 QLVKALKSAAPE 1905
QL K +P+
Sbjct: 1056 QL-KGQSQTSPD 1066
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 82.4 bits (202), Expect = 4e-15
Identities = 230/1114 (20%), Positives = 374/1114 (33%), Gaps = 147/1114 (13%)
Query: 801 TKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELR 860
T +P S P +TT++ S TL +PA ++ + + SS +
Sbjct: 2326 TSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDT 2385
Query: 861 SDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESS---DSGEPPTRDEHCG 917
S P P +S P S P S + S+ D+ P T
Sbjct: 2386 SMPTSTYSEGSTPLTS----------VPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEAS 2435
Query: 918 SGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSS-------TKSETRVPSETARTPFK 970
S P + P PP + LA +P SS T +T P T+
Sbjct: 2436 SSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASS 2495
Query: 971 SP-LLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSF 1029
SP + I P+ +++ +T + P+ T P+ SPEA + P + S
Sbjct: 2496 SPTTAEDIVVPISTASEGST--------LLTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547
Query: 1030 TVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRK 1089
T + S + TS TP R + P + +PL + + ++S
Sbjct: 2548 TSTEISSSATSAEGTSMPTSTYSEGSTPLRSM--------PVSTKPLASSEASTLS---- 2595
Query: 1090 GQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVG 1149
+TP S P + + +SSS + AK + P S L + L
Sbjct: 2596 -------TTPVDTSI------PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642
Query: 1150 LKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVT 1209
+ V L + S +S + A S P + S +T + T
Sbjct: 2643 MPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTT 2702
Query: 1210 LPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMN 1269
L + ++ S P++T+ P+ +S S + SMR S S ++ ++
Sbjct: 2703 LL-ANSEASTLSTTPVDTS--TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVS 2759
Query: 1270 GAKARSHSFSTHSGDKPSTPPIEGSGKVRTQI-ITNTAERGNSLTRQNSSTESSPNKAPS 1328
S ST S + V T I +T + E +S T + S P PS
Sbjct: 2760 TLPVASSEASTVS-----------TTAVDTSIPVTTSTEASSSPT--TAEVTSMPTSTPS 2806
Query: 1329 APMLESLPSVGRPSGH---PSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGK 1385
S P P H SS G+L ++ +S + S P +EG+++P
Sbjct: 2807 E---TSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIST 2863
Query: 1386 EDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSS---T 1442
+ + P + V S S P T P + G + P+T E +S +
Sbjct: 2864 ASEGSTLLTSIPVSTTPVASSEAS-TLSTTPVDTSIPVTTSTEG-SSSPTTAEGTSMPIS 2921
Query: 1443 SKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKP 1502
+ E S + SEA T + + E + PT+ E P
Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE---ASSSPTTAEGTSMP 2978
Query: 1503 GPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQC 1562
S G R++ L ++S M ++ SE + P
Sbjct: 2979 ----ISTPGERRTPLTSMSVSTMPVA-------------------SSEASTLSRTP---A 3012
Query: 1563 ETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTELL 1622
+T + T+++ +P + TP + L P + +PVA T T +
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLSTTPV 3071
Query: 1623 NRVDKKAAPQTESGSSNASCRNV---LKGSSQGSC-LIGSSISTQGNHKKNMKIKADMEV 1678
+ + TE SS + S+GS L G +ST + + V
Sbjct: 3072 DS-NSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPV 3130
Query: 1679 PKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRY 1738
+ V + E S M T G+ PL ST
Sbjct: 3131 DTSTPVTTSTE-------------AHSSPTTSEGTSMPTSTPSEGSTPLTYM-PVSTMLV 3176
Query: 1739 LCQPDSPEDAEPL---LPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPI 1795
+ DS A P+ P+ ++ A SS A+ + ++G P S V +T P+
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT--PV 3234
Query: 1796 MTAR----GMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWG 1851
++ P+ S P S+ SS E P + S G P+ S P+
Sbjct: 3235 ASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEG--STPLTSMPVSTTT 3292
Query: 1852 SEVAATGTQDKAPR-----MCTYSASGGSNSDSD 1880
+ T T P + TYS + S +D
Sbjct: 3293 VASSETSTLSTTPADTSTPVTTYSQASSSPPIAD 3326
Score = 76.3 bits (186), Expect = 3e-13
Identities = 274/1367 (20%), Positives = 451/1367 (32%), Gaps = 202/1367 (14%)
Query: 658 VKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGI 717
+K SSE + E P+ S+ + T NS P+G T +P +
Sbjct: 226 MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTR-MPLSV 284
Query: 718 ACLQPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRV-STESFSSRTVTQNPQQQKLVKP 776
+ SE T P N+P + STE+ SS T +
Sbjct: 285 MLV------------VSSEASTLSTTPA--ATNIPVITSTEASSSPTTAEGTSIPTSTYT 330
Query: 777 THNISCQSNSRSSAPMGIYQKQNLTKIPPRGK-----SSPQKSKLMEPEATTLLPSS--- 828
+ S S+ P+ + L+ P S+ S EAT++L S+
Sbjct: 331 EGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE 390
Query: 829 GLVTLEKSPALAPGKLSRFMKTESSGPL---------FELRSDPHIPKHSAQLPHSSRMP 879
G L P S T S+ P+ E S P + ++ + S+
Sbjct: 391 GSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTS-IATSTPSE 449
Query: 880 SRRDWVQCPKSQTPGSRSRPAIESS---DSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRS 936
P S TP + S + S+ DS T S P + P P
Sbjct: 450 GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG 509
Query: 937 VSLLARPSYDYSPAPSSTKSE-TRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKK 995
+ L S P SS S + P +T+ +P+ A S+ P T +
Sbjct: 510 STPLTSMSVSTMPVASSEASTLSTTPVDTS-----TPVTTSSEASSSSTTPEGTSIPTST 564
Query: 996 PSVA----FKKPIFTHPMPSPEAVIQTRCPA----------HAPSSSFTVMALG-PPKVS 1040
PS P+ T + S EA + PA A SSS T P
Sbjct: 565 PSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTY 624
Query: 1041 PKRG--VPKTSPRQTLGTPQRDIGLQTPRISPST--HEPLEMTSSKSVSPGRKGQLN--D 1094
+RG + S TL L T + +T E TSS + + G +
Sbjct: 625 SERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYT 684
Query: 1095 SASTPPKPSFLGVNESPSSQVS---------------SSSSSSSPAKSHNSPHGCQSAHE 1139
STP + SS+ S S+ +SSSP + + + E
Sbjct: 685 EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE 744
Query: 1140 KGLK-TRLPVGLKVLMKSPQLLRKSSTV--PGKHEKDSLNEASKSSVAVNKSKPEDSKNP 1196
T +PV K L+ S + S+T H S + + S P + +
Sbjct: 745 GSTPLTSMPVS-KTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE 803
Query: 1197 ASMEITAGERNVTLPDSQAQGSLADGLPLE-----TALQEPLESSIPG----------SD 1241
S +T+ ++T P + + S P++ T E S P S+
Sbjct: 804 GSPLLTSIPVSIT-PVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862
Query: 1242 GRDGVDNRSMRRSL--------SSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEG 1293
GR + + + +L S+ P N +ARS ++ P++ P EG
Sbjct: 863 GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEG 922
Query: 1294 SGK-----------VRTQIITNTAERGNSLTRQNSSTE--SSPNKAPSAPMLESLPSVGR 1340
S V ++ T +A ++ T +STE SSP A + S PS G
Sbjct: 923 STPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982
Query: 1341 P--SGHPSSGKGSLGSSGSFSSQHGSPSKLPLRI-------PPKSEGLLIPPGKEDQQAF 1391
+ P S S S S S PL PP +EG +P + +
Sbjct: 983 TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST 1042
Query: 1392 TQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRH 1451
P + V S S P T P S + + TS + + G
Sbjct: 1043 PLTRMPVSTTMVASSETS-TLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGST 1101
Query: 1452 PDASATATD--AVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKP--GPSFA 1507
P S + VSSEA T + + + E + PT+ E P PS
Sbjct: 1102 PLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE---ASSSPTTAEGTSIPTSPPS-- 1156
Query: 1508 SWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENE 1567
+ P S M +S T V +A L +++ +
Sbjct: 1157 ------EGTTPLAS---MPVSTTLVVSSEANTLS-----------------TTPVDSKTQ 1190
Query: 1568 LIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTE------- 1620
+ T+++ P + TP + L P RH+PVA S T T
Sbjct: 1191 VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP-VRHTPVASSEASTLSTSPVDTSTP 1249
Query: 1621 LLNRVDKKAAPQTESGSS--------------NASCRNVLKGSSQGSCLIGSSISTQG-- 1664
+ + ++P T G+S + L S + S L+ + + T+G
Sbjct: 1250 VTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPV 1309
Query: 1665 ---NHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAV-----ADSVFQSHIIESNCQMR 1716
N + A+ S E L + A S+ + ++++ +
Sbjct: 1310 VTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVT 1369
Query: 1717 TLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSS 1776
T + P G + +P + P+ S S++ A ++ P +
Sbjct: 1370 TSTEACSS-PTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGT 1428
Query: 1777 TDGQRPADSAIVHSTSDPIMT-ARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSF 1835
T + + S P T + G PL+S P S+ V++ + + P +S
Sbjct: 1429 TSAEATSSPTTAEGISIPTSTPSEGKTPLKS---IPVSNTPVANSEASTLSTTPVDSNSP 1485
Query: 1836 GYAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSASGGSNSDSDLD 1882
++S P P G+ +A + + + + + S + + S+++
Sbjct: 1486 VVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEIN 1532
Score = 73.6 bits (179), Expect = 2e-12
Identities = 177/854 (20%), Positives = 304/854 (35%), Gaps = 136/854 (15%)
Query: 755 STESFSSRTVTQNPQQQKLVKPTH-----------NISCQSNSRSSAPMGIYQKQNLTKI 803
ST S S +T P +LV + +I +++ +S+ + ++
Sbjct: 1094 STYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS 1153
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDP 863
PP ++P S P +TTL+ SS TL +P + +++ + S P E+ S P
Sbjct: 1154 PPSEGTTPLASM---PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP 1210
Query: 864 HIPKHSAQLPHSSRMPSRRDWVQCPKSQT----PGSRSRPAIESSDSGEPPTRDEHCG-- 917
P +S MP R V ++ T P S P S+++ PT E
Sbjct: 1211 TSTPGERSTPLTS-MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLP 1269
Query: 918 ---------------------SGPEAGVKSPSP-----PPPPGRSVSLLARPSYDYSPAP 951
+ PEA +P P VS P+ + + P
Sbjct: 1270 TSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPA-EGTSMP 1328
Query: 952 SSTKSETRVPSETARTPFKSPLLKG------ISAPVISSNPATTEVQ------------- 992
+ST SE R P P + L+ + PV +S P TT +
Sbjct: 1329 TSTYSEGRTP--LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSM 1386
Query: 993 -RKKPSVAFKK----PIFTHPMPSPEAVIQTRCP----------AHAPSSSFTVMALGPP 1037
PS P+ T P+ S EA + P A A SS T + P
Sbjct: 1387 PNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIP 1446
Query: 1038 KVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISP-STHEPLEMTSSKSVSPGRKGQLNDSA 1096
+P G TP + T +P ++ P+ +++ S SP + +
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506
Query: 1097 STPPKPSF------LGVNESPSSQVSS---------------SSSSSSPAKSHNSPHGCQ 1135
STP + S + SS+++S S +SSSP + +
Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS 1566
Query: 1136 SAHEKGLK-TRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSK 1194
+ E T LPV +++ S ++ + K + + EAS S+ A S +
Sbjct: 1567 TYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTP 1626
Query: 1195 NPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRS 1254
+ S +T+ + T P + + S P+++ P+ +S S + SM S
Sbjct: 1627 SEGSPLLTSIPVSTT-PVASPEASTLSTTPVDS--NSPVITSTEVSSSPTPAEGTSMPTS 1683
Query: 1255 LSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTR 1314
+ ++ + S + ST ST P++ S T + T+T R + T
Sbjct: 1684 TYTEGRTPLTSITVRTTPVASSAIST-----LSTTPVDNS----TPVTTSTEARSSPTTS 1734
Query: 1315 QNSSTESSPNKAPS--APMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRI 1372
+ + S PN PS L S+P P SS +L ++ +S + S
Sbjct: 1735 EGT---SMPNSTPSEGTTPLTSIPVSTTPV--LSSEASTLSATPIDTSTPVTTSTEATSS 1789
Query: 1373 PPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCP---PTPTDCPEALQSPG 1429
P +EG IP + P ++ V S + P +P A+ S
Sbjct: 1790 PTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSP 1849
Query: 1430 RTQHPSTFETSSTSKLETS-GRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQ 1488
++ TS+ S+ T+ P ++ T + ++ +P + + Q
Sbjct: 1850 TPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPV------TTYAQ 1903
Query: 1489 VQTKPTSVEAKQKP 1502
V + PT+ + P
Sbjct: 1904 VSSSPTTADGSSMP 1917
Score = 70.9 bits (172), Expect = 1e-11
Identities = 150/774 (19%), Positives = 262/774 (33%), Gaps = 86/774 (11%)
Query: 755 STESFSSRTVTQNPQQQKLVKPTH-----------NISCQSNSRSSAPMGIYQKQNLTKI 803
ST S + +T P LV + N +++ +S+P + ++
Sbjct: 976 STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDP 863
P S+P P +TT++ SS TL +PA ++ + + SS + S P
Sbjct: 1036 TPSEGSTPLTRM---PVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMP 1092
Query: 864 HIPKHSAQLPHSSRMPSRRDWVQCPK---SQTPGSRSRPAIESSDSGEPPTRDEHCGSGP 920
P +S S R V S TP S P S+++ PT E
Sbjct: 1093 TSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAE------ 1146
Query: 921 EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAP 980
G P+ PP G +P S S T V S A T + P
Sbjct: 1147 --GTSIPTSPPSEGT------------TPLASMPVSTTLVVSSEANTL--------STTP 1184
Query: 981 VISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPA-HAPSSSFTVMALGPPKV 1039
V S T + P + P + T P H P +S L V
Sbjct: 1185 VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPV 1244
Query: 1040 SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTP 1099
P T+ +T +P G P + S L + S + + + +TP
Sbjct: 1245 D--TSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTP 1302
Query: 1100 PKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQL 1159
+ P + SSS +PA+ + P S L T +PV ++ S
Sbjct: 1303 VD------TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPL-TSIPVNTTLVASSAIS 1355
Query: 1160 LRKSSTVPGKHEKDSLNEA-SKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGS 1218
+ ++ V + EA S + + S P + + + +T+ + T P ++ S
Sbjct: 1356 ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT-PVVSSEAS 1414
Query: 1219 LADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSF 1278
P++T S PG+ + + + +S P P+ G K+ S
Sbjct: 1415 TLSATPVDT--------STPGTTSAEATSSPTTAEGISI--PTSTPSEGKTPLKSIPVSN 1464
Query: 1279 STHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSV 1338
+ + + ST ++ T NS +++ SSP A + S PS
Sbjct: 1465 TPVANSEAST-------------LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSE 1511
Query: 1339 GRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKE----DQQAFTQG 1394
G + + +S +S +P+ + S+ P + +++G
Sbjct: 1512 GSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEG 1571
Query: 1395 ECP--SANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHP 1452
P S V+ + S+ + TP D + + +T E SS + S P
Sbjct: 1572 STPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSP 1631
Query: 1453 DASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSF 1506
++ +P + T+ + + +V + PT E P ++
Sbjct: 1632 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685
Score = 61.6 bits (148), Expect = 7e-09
Identities = 171/775 (22%), Positives = 274/775 (35%), Gaps = 116/775 (14%)
Query: 784 SNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGK 843
S SS+P T P G S+P S P +TT + SS TL +PA
Sbjct: 3256 STEASSSPPTAEGTSMPTSTPSEG-STPLTSM---PVSTTTVASSETSTLSTTPADTSTP 3311
Query: 844 LSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPK---SQTPGSRSRPA 900
++ + + SS P+ + S P P ++ S V S TP S P
Sbjct: 3312 VTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPV 3371
Query: 901 IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV 960
S+++ PT E G SPS P S+ + P + +T S T V
Sbjct: 3372 TTSTEASLSPTTAE----GTSIPTSSPSEGTTPLASMPVSTTPVVS---SEVNTLSTTPV 3424
Query: 961 PSETARTPFKSPLLKGISAPVI---SSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQ 1017
S T T + S+P I +S P +T + P P+ T P+ S EA
Sbjct: 3425 DSNTLVT----TSTEASSSPTIAEGTSLPTSTTSEGSTPLSIM--PLSTTPVASSEASTL 3478
Query: 1018 TRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLG---TPQRDIGLQTPRISPSTHE 1074
+ P +S V P SP + P T G TP ++ + T ++ S
Sbjct: 3479 STTPV---DTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAS 3535
Query: 1075 PLEMT-----------SSKSVSPGRKGQLNDSASTPPK-PSFLGVNESPSSQVSSSSSSS 1122
L T S S SP STP + S L S+ V+SS +S+
Sbjct: 3536 TLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST 3595
Query: 1123 SPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTV-PGKHEKDSLNEA-SK 1180
S + ++ + P + + M +P + T+ P +++EA +
Sbjct: 3596 PSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA 3655
Query: 1181 SSVAVNKSKP-----EDSKNPASMEIT---------AGERNVTLPDSQAQGSLADGLPLE 1226
S++ V+ S P + S +P + E T T+P S + + ++G L
Sbjct: 3656 STLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLS 3715
Query: 1227 T---ALQEPLESSIPGSDGRDGVDNRSMRRSL-------------------------SSS 1258
T P+ +S +D+ +M S+ + S
Sbjct: 3716 TPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPS 3775
Query: 1259 KPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSS 1318
P + ++ M A S S +T G +T P+ + + T + T + ++ +S
Sbjct: 3776 IPSVYTSMSMTTASEGSSSPTTLEG--TTTMPMSTTSERSTLLTTVLISPISVMSPSEAS 3833
Query: 1319 TESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSP-------SKLPLR 1371
T S+P S P+L S +G S S +S+ +P + LP
Sbjct: 3834 TLSTPPGDTSTPLLTS-----TKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTS 3888
Query: 1372 I--------PPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRS--CPPTPTDC 1421
PP P + T + +V+V+ E + + P TP
Sbjct: 3889 FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTS 3948
Query: 1422 PEALQSPGRTQHPST-------FETSSTSKLETSGRHPDASATATDAVSSEAPLS 1469
A P T ST T STS T+ T A+++ APL+
Sbjct: 3949 STADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003
Score = 60.5 bits (145), Expect = 2e-08
Identities = 147/686 (21%), Positives = 239/686 (34%), Gaps = 84/686 (12%)
Query: 819 PEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRM 878
P +TT + SS TL +P ++ + SS E S P P +S +
Sbjct: 2875 PVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSIL 2934
Query: 879 PSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVS 938
S V S+ + P D+ P T S P + P PG +
Sbjct: 2935 VST---VPVAGSEASTLSTTPV----DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987
Query: 939 LLARPSYDYSPAPSSTKSE-TRVPSETARTPFKSPLLKGISAPVISSN---PATTEVQRK 994
L S P SS S +R P++T+ TP + + S+P + P +T +
Sbjct: 2988 PLTSMSVSTMPVASSEASTLSRTPADTS-TPVTTS-TEASSSPTTAEGTGIPISTPSEGS 3045
Query: 995 KPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTL 1054
P + P+ T P+ PEA + P + S T + +SP
Sbjct: 3046 TPLTSI--PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV------------SSSPTPAE 3091
Query: 1055 GTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQ 1114
GT I + +P T P+ T S + STP S + SP++
Sbjct: 3092 GT-SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTS-TEAHSSPTTS 3149
Query: 1115 VSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDS 1174
+S +S+P++ T +PV +++ S ++ V +
Sbjct: 3150 EGTSMPTSTPSEGSTP------------LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTT 3197
Query: 1175 LNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLE 1234
EA+ S+ A S P + + +T+ + T P + ++ S+ P+++ PL
Sbjct: 3198 STEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT-PVASSEASILSTTPVDS--NTPLT 3254
Query: 1235 SSIPGSDGRDGVDNRSMRRSLSS--SKPHLK-PALGMNGAKARSHSFSTHSGD------- 1284
+S S + SM S S S P P A + + + ST D
Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314
Query: 1285 ---KPSTPPIEGSGKVRTQI-------ITNTAERGNSLTRQNSSTESSPNKAPSAPMLES 1334
S+PPI + T +TN + + +ST S+ S P+ S
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374
Query: 1335 LPS---------VGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGK 1385
+ P+ PS G L S ++ S L P L+
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTST 3434
Query: 1386 EDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKL 1445
E + T E S + E GS S P T +P + ST ST+ +
Sbjct: 3435 EASSSPTIAEGTSLPTSTTSE-GSTPLSIMPLST-------TPVASSEASTL---STTPV 3483
Query: 1446 ETSGRHPDASATATDAVSSEAPLSPT 1471
+TS +S T + ++E PT
Sbjct: 3484 DTSTPVTTSSPTNSSPTTAEVTSMPT 3509
Score = 58.5 bits (140), Expect = 6e-08
Identities = 251/1226 (20%), Positives = 430/1226 (35%), Gaps = 151/1226 (12%)
Query: 691 VTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEKNIPKDNVDN 750
VT NE+S + TPA + T +G L + + T S P DN
Sbjct: 1310 VTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT--SIPVNTTLVASSAISILSTTPVDNSTP 1367
Query: 751 VPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSS 810
V STE+ SS T ++ P N S + +S P+ + T + S
Sbjct: 1368 VT-TSTEACSSPTTSEGTSM-----PNSNPSEGTTPLTSIPV------STTPVV-----S 1410
Query: 811 PQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSA 870
+ S L T P + SP A G +S T S G L+S IP +
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEG-ISIPTSTPSEGKT-PLKS---IPVSNT 1465
Query: 871 QLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCG---SGPEAGVKSP 927
+ +S S TP + P + S+ PT E S P G +
Sbjct: 1466 PVANSEASTL---------STTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTAL 1516
Query: 928 SPPPPPGRSVSLLARPSYDYSPAPSSTKSET-----RVPSETARTPFKSPLLKGISAPVI 982
+ P +V+ S +PA +ST T P+ T ++ S P+
Sbjct: 1517 TSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLT 1576
Query: 983 SSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVS-- 1040
S +T V + + PI + + + A S + + + G P ++
Sbjct: 1577 SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI 1636
Query: 1041 PKRGVPKTSPR-QTLGTPQRDIG---LQTPRISPSTHEPLEMTS--SKSVSPGRKGQLND 1094
P P SP TL T D + + +S S+ P E TS + + + GR +
Sbjct: 1637 PVSTTPVASPEASTLSTTPVDSNSPVITSTEVS-SSPTPAEGTSMPTSTYTEGRTPLTSI 1695
Query: 1095 SASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSP---HGCQSAHEKGLKTRLPVGLK 1151
+ T P S ++ ++ V +S+ ++ ++ +SP G + + P+
Sbjct: 1696 TVRTTPVASS-AISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754
Query: 1152 VLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLP 1211
+ +P L ++ST+ S + + + + E + P S T E L
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTS---TLSEGMTPLT 1811
Query: 1212 DSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGA 1271
+ +L T P++S+ P + + SS P PA G + A
Sbjct: 1812 STPVSHTLVANSEASTLSTTPVDSNSP-----------VVTSTAVSSSP--TPAEGTSIA 1858
Query: 1272 KARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPM 1331
+ ST P + S + T + T A +T + SSP A + M
Sbjct: 1859 TSTPSEGSTALTSIPVSTTTVASSETNT-LSTTPAVTSTPVTTY-AQVSSSPTTADGSSM 1916
Query: 1332 LESLPSVGRP--SGHPSSGKGSLGSSGSFSSQHGSPSKLPLRI-------PPKSEGLLIP 1382
S P GRP + P S S + S + ++ P+ P ++G +P
Sbjct: 1917 PTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMP 1976
Query: 1383 PGKEDQQAFTQGECP--SANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETS 1440
A+++G P S ++ S+ + TP D T P+T T
Sbjct: 1977 -----TPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVD----------TSTPATTSTE 2021
Query: 1441 STSKLETSGRHPDASATATDAVSSEA--PLSPTI---EEKVMLCIQENVEKGQVQTKPTS 1495
+S T+G ++T ++ + A P+S T+ E L K QV +
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081
Query: 1496 VEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEK 1555
+ G S P L+S + +S T V +A L S +
Sbjct: 2082 SSSATAEGSSMT--ISAPSEGSPLLTS--IPLSTTPVASPEASTL--------STTPVDS 2129
Query: 1556 KKPELQCETENELIKDTKSADNPDGGLQSKNNRRTP-QDIYNQLKIEPRNRHSPVACSTK 1614
P + T E+ + + ++RRTP + + + S ++ +
Sbjct: 2130 NSPVI---TSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPV 2186
Query: 1615 DTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMK-IK 1673
DT T + N + +++P T G+S + +GS+ + + S++ + +
Sbjct: 2187 DT-STPVTNSTEARSSPTTSEGTSMPT-STPSEGSTPFTSMPVSTMPVVTSEASTLSATP 2244
Query: 1674 ADMEVPKDSLVKEANENLQEDEDDAVADSVFQ-----------SHIIESNCQMRTLDSG- 1721
D P + EA + E ++ S SH + +N ++ TL +
Sbjct: 2245 VDTSTPVTTST-EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTP 2303
Query: 1722 -IGTFPLPDSGNRST------GRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTL----- 1769
P S S+ G + S E PL + + + V+S TL
Sbjct: 2304 VDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPA 2363
Query: 1770 EREVPSSTDGQRPADSAIVHSTSDPIMT-ARGMRPLQSRLPKPASSGKVSSQKQNEAEPR 1828
+ P +T Q + TS P T + G PL S P S+ V S + +
Sbjct: 2364 DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTS---VPVSTMPVVSSEASTHSTT 2420
Query: 1829 PQTCSSFGYAEDPMASQPLPDWGSEV 1854
P S+ +S P G+ +
Sbjct: 2421 PVDTSTPVTTSTEASSSPTTAEGTSI 2446
Score = 57.4 bits (137), Expect = 1e-07
Identities = 185/877 (21%), Positives = 303/877 (34%), Gaps = 120/877 (13%)
Query: 736 EEDTEKNIPKDNVDNVPRV-STESFSSRTVTQNPQQQKLV-----KPTHNISCQSNSRSS 789
E T P D+ N P + STE SS T + P +I+ ++ +S
Sbjct: 1647 EASTLSTTPVDS--NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVAS 1704
Query: 790 APMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTL---LPSSGLVTLEKSPALAPGKLSR 846
+ + + P S+ +S E T++ PS G L P LS
Sbjct: 1705 SAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSS 1764
Query: 847 FMKTESSGPL---------FELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRS 897
T S+ P+ E S P + ++ +P S+ P S T + S
Sbjct: 1765 EASTLSATPIDTSTPVTTSTEATSSPTTAEGTS-IPTSTLSEGMTPLTSTPVSHTLVANS 1823
Query: 898 RPAIESS---DSGEPPTRDEHCGSGPEA--GVKSPSPPPPPGRSVSLLARPSYDYSPAPS 952
+ S+ DS P S P G + P G S +L + P + A S
Sbjct: 1824 EASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEG-STALTSIPVSTTTVASS 1882
Query: 953 STKSETRVPSETARTPFKSPLLKGISAPVI---SSNPATTEVQRKKPSVAFKKPIFTHPM 1009
T + + P+ T+ TP + + S+P SS P +T + + P + P+ T +
Sbjct: 1883 ETNTLSTTPAVTS-TPVTT-YAQVSSSPTTADGSSMPTSTPREGRPPLTSI--PVSTTTV 1938
Query: 1010 PSPE--AVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPR 1067
S E + T P +++ S P T+ ++ TP G
Sbjct: 1939 ASSEINTLSTTLADTRTPVTTY----------SQASSSPTTADGTSMPTPAYSEGS---- 1984
Query: 1068 ISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKS 1127
+P T PL T S STP S G + SP++ +S +S+P++
Sbjct: 1985 -TPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG-SSSPTTAGGTSIQTSTPSER 2042
Query: 1128 HNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNK 1187
G +PV +++ S ++ V K + + EAS S+ A
Sbjct: 2043 TTPLAG------------MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090
Query: 1188 SKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLET-----ALQEPLESSIPGSDG 1242
S + + S +T+ + T P + + S P+++ E S IP
Sbjct: 2091 SMTISAPSEGSPLLTSIPLSTT-PVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149
Query: 1243 RDGVDNRSMRRSLSSSKPHLKPALGM------------------NGAKARSHSFSTHSGD 1284
S RR+ +S P + N +ARS ++
Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209
Query: 1285 KPSTPPIEGSGK-----------VRTQIITNTAERGNSLTRQNSSTE--SSPNKA----- 1326
P++ P EGS V ++ T +A ++ T +STE SSP A
Sbjct: 2210 MPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSI 2269
Query: 1327 PSAPMLE-SLPSVGRPSGH---PSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIP 1382
P++ + E + P P H +S +L ++ S+ + S PP +EG +P
Sbjct: 2270 PTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329
Query: 1383 PGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSST 1442
+ P + V S S P T P S + + +TS
Sbjct: 2330 TSTSSEGNTPLTRMPVSTTMVASFETS-TLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388
Query: 1443 SKLETSGRHPDAS--ATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEA-- 1498
+ + G P S + VSSEA T + + E + PT+ E
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE---ASSSPTTAEGTS 2445
Query: 1499 --KQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVE 1533
P S P +SS +S T V+
Sbjct: 2446 IPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVD 2482
Score = 53.5 bits (127), Expect = 2e-06
Identities = 188/964 (19%), Positives = 338/964 (35%), Gaps = 117/964 (12%)
Query: 951 PSSTKSE-----TRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIF 1005
P ST SE T +P+ T + S + ++ PV S P T Q + P
Sbjct: 207 PKSTNSEGSTPLTSMPASTMKVA-SSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSL 265
Query: 1006 THPMPSPEAVIQTRCPAH---APSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIG 1062
++ PS + TR P SS + ++ P + +P + + +P G
Sbjct: 266 SNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATN----IPVITSTEASSSPTTAEG 321
Query: 1063 LQTPRISPSTHEPLEMTSS-KSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSS 1121
P S T +TS+ S P +++ + TP S L + S + +++ +
Sbjct: 322 TSIP-TSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEA 380
Query: 1122 SSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKS 1181
+S S S T +PV ++ S + V K + +EAS S
Sbjct: 381 TSMLTSTLSEGSTP-------LTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSS 433
Query: 1182 -----SVAVNKSKPEDSKNP-ASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLES 1235
++ S P + P SM ++ T P + ++ S P+++ Q + +
Sbjct: 434 PTTAEDTSIATSTPSEGSTPLTSMPVS------TTPVASSEASNLSTTPVDSKTQ--VTT 485
Query: 1236 SIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSG 1295
S S + SM S S ++ ++ S ST ST P++ S
Sbjct: 486 STEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST-----LSTTPVDTS- 539
Query: 1296 KVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGR--PSGHPSSGKGSLG 1353
T + T++ +S T + +S +S S P L ++P R S S+ +
Sbjct: 540 ---TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP-LTNMPVSTRLVVSSEASTTSTTPA 595
Query: 1354 SSGSF---SSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSD 1410
S +F SS+ S S +EG +P ++ T S + ++ +
Sbjct: 596 DSNTFVTTSSEASSSS-------TTAEGTSMPTSTYSERGTTITSM-SVSTTLVASSEAS 647
Query: 1411 RRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDAS--ATATDAVSSEAPL 1468
S P ++ P + + + TS + T G P S T SSEA
Sbjct: 648 TLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAST 707
Query: 1469 SPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDIS 1528
T + + E + PT+ + P + + + P S M +S
Sbjct: 708 LSTTPVDTSTPVTTSTE---ASSSPTTADGASMPTSTPS------EGSTPLTS---MPVS 755
Query: 1529 KTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNR 1588
KT + +A L +T + T+++ +P +
Sbjct: 756 KTLLTSSEASTLS-----------------TTPLDTSTHITTSTEASCSPTTTEGTSMPI 798
Query: 1589 RTPQDIYNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKG 1648
TP + L P + +PV T T VD + T + S++
Sbjct: 799 STPSEGSPLLTSIPVS-ITPVTSPEASTLST---TPVDSNSPVTTSTEVSSSPT------ 848
Query: 1649 SSQGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHI 1708
++G+ + S+ S +M + + V ++ + + + S
Sbjct: 849 PAEGTSMPTSTYSEGRTPLTSMPVSTTL-VATSAISTLSTTPVDTSTPVTNSTEARSSPT 907
Query: 1709 IESNCQMRTLDSGIGTFPL---PDSGN---RSTGRYLCQPDSPED-AEPLLPLQSALSAV 1761
M T G G+ PL PDS S R L +P D + P+ A S+
Sbjct: 908 TSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSA--TPVDTSTPVTTSTEATSSP 965
Query: 1762 SSMRAQTLEREVPSSTDGQRPADSAIVHST--SDPIMTARGMRPLQSRLPKPASSGKVSS 1819
++ ++ PS +G P S V T ++ + P+ S P S+ S
Sbjct: 966 TTAEGTSIPTSTPS--EGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSP 1023
Query: 1820 QKQNEAEPRPQTCSSFG---YAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSASGGSN 1876
E P + S G P+++ + + +T D + + TYS + S+
Sbjct: 1024 PPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSS 1083
Query: 1877 SDSD 1880
+ +D
Sbjct: 1084 TTAD 1087
Score = 53.5 bits (127), Expect = 2e-06
Identities = 134/623 (21%), Positives = 232/623 (37%), Gaps = 67/623 (10%)
Query: 890 SQTPGSRSRPAIESSDSGEPPTRDEHC---------GSGPEAGVKSPSPPPPPGRSVSLL 940
S+TP S P S+++ PT E GS P + + P + +L
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS 3067
Query: 941 ARPSYDYSPAPSSTK-SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVA 999
P SP +ST+ S + P+E P S +G S P+ +TT V S
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPI-STYSEG-STPLTGVPVSTTPVTSSAISTL 3125
Query: 1000 FKKPI--------FTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPK----VSPKRGVPK 1047
P+ T SP T P PS T + P VS +
Sbjct: 3126 STTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLS 3185
Query: 1048 TSPRQTLGTPQRDIGLQTPRISPSTHEPLEM---TSSKSVSPGRKGQLNDSASTPPKPSF 1104
+P T TP + T S +T E + T S+ ++P ++++ + S
Sbjct: 3186 ATPVDT-STP---VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI 3241
Query: 1105 LGVN--ESPSSQVSSSSSSSSP--AKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLL 1160
L +S + +S+ +SSSP A+ + P S L T +PV + S
Sbjct: 3242 LSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPL-TSMPVSTTTVASSETST 3300
Query: 1161 RKSSTVPGKHEKDSLNEASKS-SVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSL 1219
++ + ++AS S +A S P + + S +T + T P ++ S
Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTT-PVVSSEAST 3359
Query: 1220 ADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFS 1279
P++T+ P+ +S S + S+ S S ++ ++ S +
Sbjct: 3360 LSTTPVDTS--TPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVN 3417
Query: 1280 THSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVG 1339
T ST P++ + T + T+T + + +S +S S P L +P
Sbjct: 3418 T-----LSTTPVDSN----TLVTTSTEASSSPTIAEGTSLPTSTTSEGSTP-LSIMPLST 3467
Query: 1340 RPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSA 1399
P SS +L ++ +S + S P +E +P +G P
Sbjct: 3468 TPVA--SSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG-----EGSTPLT 3520
Query: 1400 NVAVLGEP--GSDRRSCPPTPTDCPEALQSPGR-TQHPSTFETSSTSKLETSGRHPDASA 1456
N+ V P S+ + TP D + S + + P+T + +T ++ T +
Sbjct: 3521 NMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV-TTMRMSTPSEGSSSLT 3579
Query: 1457 T----ATDAVSSEA--PLSPTIE 1473
T +T SSEA P +P+++
Sbjct: 3580 TMLLSSTYVTSSEASTPSTPSVD 3602
Score = 38.5 bits (88), Expect = 0.063
Identities = 144/764 (18%), Positives = 260/764 (34%), Gaps = 109/764 (14%)
Query: 1163 SSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME------ITAGERNVT------- 1209
SST E + +E++ S + S ED+ +P + E T E +++
Sbjct: 106 SSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVS 165
Query: 1210 ---LPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSS--SKPHLK- 1263
LP +A SL + + T PL +S S ++ ++ +S +S S P
Sbjct: 166 TAPLPSFEAYTSLTYKVDMST----PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSM 221
Query: 1264 PALGMNGAKARSHSFSTHSGD--KPSTPPIEGSGKVRT---QIITNTAERGNS--LTR-- 1314
PA M A + + + T + P T + S T ++N+A G S LTR
Sbjct: 222 PASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMP 281
Query: 1315 --------QNSSTESSPNKAPSAPML-----ESLPSVGRPSGHPSS----GKGSLGSSGS 1357
+ST S+ A + P++ S P+ + P+S G L S+ +
Sbjct: 282 LSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPA 341
Query: 1358 FSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPT 1417
+ + L I P L+ E T E S + L E GS + P
Sbjct: 342 STMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE-GSTPLTNMPV 400
Query: 1418 PTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVM 1477
T + ++ + P +T T+ E S A T+ + +P V
Sbjct: 401 STILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVS 460
Query: 1478 LCIQENVEKGQVQTKP--------TSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISK 1529
+ E + T P TS EA P + + + M +S
Sbjct: 461 TTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVST 520
Query: 1530 TKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRR 1589
V +A L S + P T +E + S+ P+G +
Sbjct: 521 MPVASSEASTL--------STTPVDTSTP---VTTSSEA---SSSSTTPEG---TSIPTS 563
Query: 1590 TPQDIYNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGS 1649
TP + L P + V+ T T D T S +S++S +
Sbjct: 564 TPSEGSTPLTNMPVSTRLVVSSEASTTSTTP----ADSNTFVTTSSEASSSST------T 613
Query: 1650 SQGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHII 1709
++G+ + S+ S +G +M + + ++ S + +
Sbjct: 614 AEGTSMPTSTYSERGTTITSMSVSTTLVASSEA-------------------STLSTTPV 654
Query: 1710 ESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTL 1769
+SN + T + + + T Y + +P + P+ A S S++ +
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMPTSTY-TEGSTPLTSMPVNTTLVASSEASTLSTTPV 713
Query: 1770 EREVPSSTDGQRPADSAIVHSTSDPIMT-ARGMRPLQSRLPKPASSGKVSSQKQNEAEPR 1828
+ P +T + + S P T + G PL S P S ++S + +
Sbjct: 714 DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTS---MPVSKTLLTSSEASTLSTT 770
Query: 1829 PQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSAS 1872
P S+ + P G+ + + + +P + + S
Sbjct: 771 PLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVS 814
Score = 36.2 bits (82), Expect = 0.31
Identities = 53/201 (26%), Positives = 73/201 (36%), Gaps = 25/201 (12%)
Query: 943 PSYDYSPAPSSTKSETRVPS-ETARTPFKSPLLKGISAPVIS--SNPATTEVQRKKPSVA 999
P + P S T PS +TA TP P+ IS VI+ S P TT P +
Sbjct: 3890 PGASIASTPPLDTSTTFTPSTDTASTP-TIPVATTISVSVITEGSTPGTTIFIPSTPVTS 3948
Query: 1000 FKKPIF--THPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTP 1057
+F T S + T + SSS T + K T+P T P
Sbjct: 3949 STADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEF-------TTPAMTTAAP 4001
Query: 1058 QRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSS 1117
+ + T +P T TS+ ++S + S +T P +PSS+
Sbjct: 4002 LTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRP--------VTPSSE--- 4050
Query: 1118 SSSSSSPAKSHNSPHGCQSAH 1138
SS S SH P AH
Sbjct: 4051 -SSRPSTITSHTIPPTFPPAH 4070
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 72.8 bits (177), Expect = 3e-12
Identities = 155/754 (20%), Positives = 256/754 (33%), Gaps = 89/754 (11%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNI--SCQSNSRSSAPMGIYQKQNLTKIPPRGKS 809
P ++T + T + P +PT S + + AP TK P
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP-------TTTKSAPTTPK 260
Query: 810 SPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHS 869
P + EP TT P T K PA T S P P PK
Sbjct: 261 EPAPTTTKEPAPTT--PKEPAPTTTKEPAPT---------TTKSAPTTPKEPAPTTPKKP 309
Query: 870 AQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGV----K 925
A P+ PK TP + PA + + P T E + P+ K
Sbjct: 310 APTTPKEPAPTT------PKEPTPTTPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPK 362
Query: 926 SPSPPPP--PGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKS-PLLKGISAPVI 982
P+P P P + + P+ PAP++TKS E A T KS P +P
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 983 SSNPATTEVQRKKPSVAFKKPIFTHPM-PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP 1041
+ PA T + P+ KKP T P P+P P P +P
Sbjct: 423 TKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTT----------PKEPAPTTTKKPAPTTP 471
Query: 1042 KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPK 1101
K P T+P++T T + +++P+T E L T+ + +P +L + P
Sbjct: 472 KEPAP-TTPKETAPTTPK-------KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAK---------SHNSPHGCQSAHEKGLKTRLPVGLKV 1152
P+ E P+ +++ ++P + + +P K P G
Sbjct: 524 PT---TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG--- 577
Query: 1153 LMKSPQLLRK-SSTVPGK-HEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
+P L++ + T P K K+ +K + KP + + T E T
Sbjct: 578 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 635
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
P A + P T L+EP ++ P + + + S++ P
Sbjct: 636 PKEPAPTTPKGTAP--TTLKEPAPTT-PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 1271 AKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAP 1330
A + + KP+ E +++ T T + T S ES+P + + P
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTP-ELSAEP 750
Query: 1331 MLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA 1390
++L + + G P++ + ++ ++ LR P E P + A
Sbjct: 751 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKETA 808
Query: 1391 FTQGECPSANVAVLGEPGSDRRSCPPTP---TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
T + + + + + TP T +P T T T+
Sbjct: 809 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 868
Query: 1448 SGRHPDASATATDAVS------SEAPLSPTIEEK 1475
P AT + A + ++AP PT +K
Sbjct: 869 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 902
Score = 64.3 bits (155), Expect = 1e-09
Identities = 183/939 (19%), Positives = 308/939 (32%), Gaps = 138/939 (14%)
Query: 728 DYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSR 787
DY F +D +KN K P V E+ S + K+ P + + Q N
Sbjct: 58 DYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGL----DNGDFKVTTPDTSTT-QHNKV 112
Query: 788 SSAPMGIYQK--QNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLS 845
S++P K +PP +S + S + E T + + T K + + +
Sbjct: 113 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEKT 170
Query: 846 RFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPA----- 900
K S + K A+ + ++ + PK TP + PA
Sbjct: 171 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 230
Query: 901 --IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPP-----PGRSVSLLARPSYDYSPAPSS 953
++ P T E + ++ +P P P P + P+ PAP++
Sbjct: 231 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290
Query: 954 TKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPE 1013
TKS P E A T K P AP PA T + P+ K+P T P+P
Sbjct: 291 TKSAPTTPKEPAPTTPKKP------APTTPKEPAPTTPKEPTPTTP-KEPAPTTKEPAPT 343
Query: 1014 AVIQTRCPA-HAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPST 1072
+ PA AP P +PK P T+ + TP+ T +T
Sbjct: 344 T---PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 1073 HEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAK----SH 1128
EP T+ SA T PK + P+ + ++P K +
Sbjct: 401 KEPAPTTTK-------------SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 1129 NSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKS 1188
P T+ P K P T P +K + K +
Sbjct: 448 KEPAPTTPKEPAPTTTKKPA--PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA-PTTPE 504
Query: 1189 KPEDSKNPASMEITAGERNVTLPDSQA---QGSLADGLPLETALQEPLESSIPGSDGRDG 1245
KP + T E T P+ A + A P E A P E +
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------- 555
Query: 1246 VDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNT 1305
+ + ++ P A +T P+TP ++ T
Sbjct: 556 --PTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTP----KKPAPKELAPTT 603
Query: 1306 AERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSP 1365
+ S T + + AP+ P + + P+ P++ KG+ ++
Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTT---------- 651
Query: 1366 SKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD-CPEA 1424
K P PK P KE T+G P++ + P + + + P TP + P
Sbjct: 652 LKEPAPTTPKK-----PAPKELAPTTTKG--PTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 1425 LQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENV 1484
+ P T + T+S T+ + P + D + E PT
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT------------- 751
Query: 1485 EKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGN 1544
P ++E K G ++ PA + K +++ T +K
Sbjct: 752 --------PKALENSPKEP-------GVPTTKTPA--ATKPEMTTTAKDKTT-------E 787
Query: 1545 RQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDI--YNQLKIEP 1602
R L++ + P++ ET K T+S ++ T QD + ++
Sbjct: 788 RDLRTTPETTTAAPKMTKETATTTEKTTESKIT---ATTTQVTSTTTQDTTPFKITTLKT 844
Query: 1603 RNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNAS 1641
V + K TE++N+ ++ A P+ + +S A+
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 883
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 72.8 bits (177), Expect = 3e-12
Identities = 155/754 (20%), Positives = 256/754 (33%), Gaps = 89/754 (11%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNI--SCQSNSRSSAPMGIYQKQNLTKIPPRGKS 809
P ++T + T + P +PT S + + AP TK P
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP-------TTTKSAPTTPK 301
Query: 810 SPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHS 869
P + EP TT P T K PA T S P P PK
Sbjct: 302 EPAPTTTKEPAPTT--PKEPAPTTTKEPAPT---------TTKSAPTTPKEPAPTTPKKP 350
Query: 870 AQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGV----K 925
A P+ PK TP + PA + + P T E + P+ K
Sbjct: 351 APTTPKEPAPTT------PKEPTPTTPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPK 403
Query: 926 SPSPPPP--PGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKS-PLLKGISAPVI 982
P+P P P + + P+ PAP++TKS E A T KS P +P
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463
Query: 983 SSNPATTEVQRKKPSVAFKKPIFTHPM-PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP 1041
+ PA T + P+ KKP T P P+P P P +P
Sbjct: 464 TKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTT----------PKEPAPTTTKKPAPTTP 512
Query: 1042 KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPK 1101
K P T+P++T T + +++P+T E L T+ + +P +L + P
Sbjct: 513 KEPAP-TTPKETAPTTPK-------KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAK---------SHNSPHGCQSAHEKGLKTRLPVGLKV 1152
P+ E P+ +++ ++P + + +P K P G
Sbjct: 565 PT---TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG--- 618
Query: 1153 LMKSPQLLRK-SSTVPGK-HEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
+P L++ + T P K K+ +K + KP + + T E T
Sbjct: 619 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 676
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
P A + P T L+EP ++ P + + + S++ P
Sbjct: 677 PKEPAPTTPKGTAP--TTLKEPAPTT-PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 1271 AKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAP 1330
A + + KP+ E +++ T T + T S ES+P + + P
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTP-ELSAEP 791
Query: 1331 MLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA 1390
++L + + G P++ + ++ ++ LR P E P + A
Sbjct: 792 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKETA 849
Query: 1391 FTQGECPSANVAVLGEPGSDRRSCPPTP---TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
T + + + + + TP T +P T T T+
Sbjct: 850 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 909
Query: 1448 SGRHPDASATATDAVS------SEAPLSPTIEEK 1475
P AT + A + ++AP PT +K
Sbjct: 910 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 943
Score = 64.3 bits (155), Expect = 1e-09
Identities = 183/939 (19%), Positives = 308/939 (32%), Gaps = 138/939 (14%)
Query: 728 DYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSR 787
DY F +D +KN K P V E+ S + K+ P + + Q N
Sbjct: 99 DYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGL----DNGDFKVTTPDTSTT-QHNKV 153
Query: 788 SSAPMGIYQK--QNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLS 845
S++P K +PP +S + S + E T + + T K + + +
Sbjct: 154 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEKT 211
Query: 846 RFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPA----- 900
K S + K A+ + ++ + PK TP + PA
Sbjct: 212 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 271
Query: 901 --IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPP-----PGRSVSLLARPSYDYSPAPSS 953
++ P T E + ++ +P P P P + P+ PAP++
Sbjct: 272 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331
Query: 954 TKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPE 1013
TKS P E A T K P AP PA T + P+ K+P T P+P
Sbjct: 332 TKSAPTTPKEPAPTTPKKP------APTTPKEPAPTTPKEPTPTTP-KEPAPTTKEPAPT 384
Query: 1014 AVIQTRCPA-HAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPST 1072
+ PA AP P +PK P T+ + TP+ T +T
Sbjct: 385 T---PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 1073 HEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAK----SH 1128
EP T+ SA T PK + P+ + ++P K +
Sbjct: 442 KEPAPTTTK-------------SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 1129 NSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKS 1188
P T+ P K P T P +K + K +
Sbjct: 489 KEPAPTTPKEPAPTTTKKPA--PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA-PTTPE 545
Query: 1189 KPEDSKNPASMEITAGERNVTLPDSQA---QGSLADGLPLETALQEPLESSIPGSDGRDG 1245
KP + T E T P+ A + A P E A P E +
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------- 596
Query: 1246 VDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNT 1305
+ + ++ P A +T P+TP ++ T
Sbjct: 597 --PTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTP----KKPAPKELAPTT 644
Query: 1306 AERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSP 1365
+ S T + + AP+ P + + P+ P++ KG+ ++
Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTT---------- 692
Query: 1366 SKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD-CPEA 1424
K P PK P KE T+G P++ + P + + + P TP + P
Sbjct: 693 LKEPAPTTPKK-----PAPKELAPTTTKG--PTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 1425 LQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENV 1484
+ P T + T+S T+ + P + D + E PT
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT------------- 792
Query: 1485 EKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGN 1544
P ++E K G ++ PA + K +++ T +K
Sbjct: 793 --------PKALENSPKEP-------GVPTTKTPA--ATKPEMTTTAKDKTT-------E 828
Query: 1545 RQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDI--YNQLKIEP 1602
R L++ + P++ ET K T+S ++ T QD + ++
Sbjct: 829 RDLRTTPETTTAAPKMTKETATTTEKTTESKIT---ATTTQVTSTTTQDTTPFKITTLKT 885
Query: 1603 RNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNAS 1641
V + K TE++N+ ++ A P+ + +S A+
Sbjct: 886 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 924
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 72.8 bits (177), Expect = 3e-12
Identities = 155/754 (20%), Positives = 256/754 (33%), Gaps = 89/754 (11%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNI--SCQSNSRSSAPMGIYQKQNLTKIPPRGKS 809
P ++T + T + P +PT S + + AP TK P
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP-------TTTKSAPTTPK 353
Query: 810 SPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHS 869
P + EP TT P T K PA T S P P PK
Sbjct: 354 EPAPTTTKEPAPTT--PKEPAPTTTKEPAPT---------TTKSAPTTPKEPAPTTPKKP 402
Query: 870 AQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGV----K 925
A P+ PK TP + PA + + P T E + P+ K
Sbjct: 403 APTTPKEPAPTT------PKEPTPTTPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPK 455
Query: 926 SPSPPPP--PGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKS-PLLKGISAPVI 982
P+P P P + + P+ PAP++TKS E A T KS P +P
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 983 SSNPATTEVQRKKPSVAFKKPIFTHPM-PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP 1041
+ PA T + P+ KKP T P P+P P P +P
Sbjct: 516 TKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTT----------PKEPAPTTTKKPAPTTP 564
Query: 1042 KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPK 1101
K P T+P++T T + +++P+T E L T+ + +P +L + P
Sbjct: 565 KEPAP-TTPKETAPTTPK-------KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAK---------SHNSPHGCQSAHEKGLKTRLPVGLKV 1152
P+ E P+ +++ ++P + + +P K P G
Sbjct: 617 PT---TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG--- 670
Query: 1153 LMKSPQLLRK-SSTVPGK-HEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
+P L++ + T P K K+ +K + KP + + T E T
Sbjct: 671 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
P A + P T L+EP ++ P + + + S++ P
Sbjct: 729 PKEPAPTTPKGTAP--TTLKEPAPTT-PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 1271 AKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAP 1330
A + + KP+ E +++ T T + T S ES+P + + P
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTP-ELSAEP 843
Query: 1331 MLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA 1390
++L + + G P++ + ++ ++ LR P E P + A
Sbjct: 844 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKETA 901
Query: 1391 FTQGECPSANVAVLGEPGSDRRSCPPTP---TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
T + + + + + TP T +P T T T+
Sbjct: 902 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 961
Query: 1448 SGRHPDASATATDAVS------SEAPLSPTIEEK 1475
P AT + A + ++AP PT +K
Sbjct: 962 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 995
Score = 64.3 bits (155), Expect = 1e-09
Identities = 183/959 (19%), Positives = 324/959 (33%), Gaps = 144/959 (15%)
Query: 735 SEEDTEKNIPKDNVDNVPRVSTESFSS--------RTVTQNPQQQKLVKPTHNISCQSNS 786
SEE TE++ +N ++ S+ S SS + N + QK +K N ++
Sbjct: 110 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 169
Query: 787 RSSAPMGIYQKQNLT------KIPPRGKSSPQKSKLM-EPEATTLLPSSGLVTL------ 833
+ + + + K+ S+ Q +K+ P+ TT P + +L
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229
Query: 834 EKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPK---S 890
K +L K + E++ + +D SA+ S S +D K
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 891 QTPGSRSR---PAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDY 947
TP + + PA+ + P T E + P K P+P ++ + P+
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTP----KEPTP-------TTIKSAPTTPK 338
Query: 948 SPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTH 1007
PAP++TKS P E A T K P AP PA T + P+ P
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEP------APTTPKEPAPTTTKEPAPTTTKSAP---- 388
Query: 1008 PMPSPEAVIQTRCPA-HAPSSSFTVMALGPPKVSPKRGVPKT-SPRQTLGTPQRDIGLQT 1065
P A + PA P P +PK P T P T TP+
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT--TPKEPAPTAP 446
Query: 1066 PRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPA 1125
+ +P+T + T+ K +P + S +TP +P +P++ S+ +++ PA
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEP-------APTTTKSAPTTTKEPA 497
Query: 1126 KSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAV 1185
+ T+ P +P +K + K E +
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTT 556
Query: 1186 NKSKPEDSKNPA-------------SMEITAGERNV-TLPDSQAQGSLADGLPLETALQE 1231
K P K PA + T E+ T P+ A + + P
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 1232 PLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKA--RSHSFSTHSGDKPST- 1288
P P + + ++ P A + + +T G P+T
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1289 ---PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHP 1345
P ++ T + S T + + AP+ P + + P+ P
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--P 734
Query: 1346 SSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLG 1405
++ KG+ ++ K P PK P KE T+G P++ +
Sbjct: 735 TTPKGTAPTT----------LKEPAPTTPKK-----PAPKELAPTTTKG--PTSTTSDKP 777
Query: 1406 EPGSDRRSCPPTPTD-CPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSS 1464
P + + + P TP + P + P T + T+S T+ + P + D +
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 1465 EAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRK 1524
E PT P ++E K G ++ PA + K
Sbjct: 838 ELSAEPT---------------------PKALENSPKEP-------GVPTTKTPA--ATK 867
Query: 1525 MDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQS 1584
+++ T +K R L++ + P++ ET K T+S +
Sbjct: 868 PEMTTTAKDKTT-------ERDLRTTPETTTAAPKMTKETATTTEKTTESKIT---ATTT 917
Query: 1585 KNNRRTPQDI--YNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNAS 1641
+ T QD + ++ V + K TE++N+ ++ A P+ + +S A+
Sbjct: 918 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 976
Score = 45.8 bits (107), Expect = 4e-04
Identities = 111/587 (18%), Positives = 185/587 (31%), Gaps = 72/587 (12%)
Query: 910 PTRDEHCGS--GPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTK------------ 955
P + C P + S PPP G S ++ + + SP P + K
Sbjct: 57 PDYESFCAEVHNPTSPPSSKKAPPPSGASQTI--KSTTKRSPKPPNKKKTKKVIESEEIT 114
Query: 956 -----SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMP 1010
SE + S ++ + S ++ I + S N A +KK V K T P
Sbjct: 115 EEHSVSENQESSSSSSSSSSSSTIRKIKS---SKNSAANRELQKKLKVKDNKKNRTKKKP 171
Query: 1011 SPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISP 1070
+P+ + + + F V P + + TSP+ T P P
Sbjct: 172 TPKPPVVDEAGSGLDNGDFKVTT--PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229
Query: 1071 STHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS 1130
S L + +V N ST K E+ S + +S+ + +K
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 1131 PHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKP 1190
P KG P K P + T P + + E + +++ KS P
Sbjct: 290 PTPKAETTTKGPALTTP-------KEP-----TPTTPKEPASTTPKEPTPTTI---KSAP 334
Query: 1191 EDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRS 1250
K PA T + T P A + + P P + P
Sbjct: 335 TTPKEPAP---TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 1251 MRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGN 1310
+ ++ K KPA +T P+TP T T +
Sbjct: 392 KEPAPTTPK---KPAP------------TTPKEPAPTTPKEP----------TPTTPKEP 426
Query: 1311 SLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPL 1370
+ T + + + AP+AP + + P+ P++ K ++ S P
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTKEPSPTTPKEPAPT 484
Query: 1371 RIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD-CPEALQSPG 1429
P + A T + PS P + + P TP P + P
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 1430 RTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKV 1476
T T++ T+ + P + A ++ L+PT EK+
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Score = 35.0 bits (79), Expect = 0.70
Identities = 96/461 (20%), Positives = 150/461 (32%), Gaps = 71/461 (15%)
Query: 1073 HEPLEMTSSKSVSP--GRKGQLNDSASTPPKP-----------SFLGVNESPSSQVSSSS 1119
H P SSK P G + + PKP S E S+ SS
Sbjct: 67 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 126
Query: 1120 SSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SSSS + S ++ +S+ L LKV KD+ +
Sbjct: 127 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-------------------KDNKKNRT 167
Query: 1180 KSSVAVNKSKPEDS-KNPASMEITAGERNVTLPD-SQAQGSLADGLPLETALQ--EPLES 1235
K K P+ + A + G+ VT PD S Q + P T + P S
Sbjct: 168 K-----KKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 222
Query: 1236 SIPGSDGRDGVDNRSMRRSLSSSK--PHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEG 1293
P SD + + +K +G + + + T S +K S +
Sbjct: 223 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 282
Query: 1294 SGKVRTQII--TNTAERGNSLTRQNSSTESSPNKAPSAPMLESLP-SVGRPSGHPSSGKG 1350
+ KV + T +G +LT T ++P + S E P ++ P
Sbjct: 283 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 1351 SLGSSGSFSSQHGSP--SKLPLRIPPKSEGLLI---PPGKEDQQAFTQGECPSANVAVLG 1405
+ S + + +P +K P PK P + A T + P+
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 1406 EPGSDRRSCPPTPTD-CPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSS 1464
P + + P TP + P + P P+T E + T+ E + P A T
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPAPTAPKKPAPTTP--KE 456
Query: 1465 EAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPS 1505
AP +P E TK S ++P P+
Sbjct: 457 PAPTTPK-------------EPAPTTTKEPSPTTPKEPAPT 484
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 72.8 bits (177), Expect = 3e-12
Identities = 155/754 (20%), Positives = 256/754 (33%), Gaps = 89/754 (11%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHNI--SCQSNSRSSAPMGIYQKQNLTKIPPRGKS 809
P ++T + T + P +PT S + + AP TK P
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP-------TTTKSAPTTPK 394
Query: 810 SPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHS 869
P + EP TT P T K PA T S P P PK
Sbjct: 395 EPAPTTTKEPAPTT--PKEPAPTTTKEPAPT---------TTKSAPTTPKEPAPTTPKKP 443
Query: 870 AQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGV----K 925
A P+ PK TP + PA + + P T E + P+ K
Sbjct: 444 APTTPKEPAPTT------PKEPTPTTPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPK 496
Query: 926 SPSPPPP--PGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKS-PLLKGISAPVI 982
P+P P P + + P+ PAP++TKS E A T KS P +P
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 983 SSNPATTEVQRKKPSVAFKKPIFTHPM-PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP 1041
+ PA T + P+ KKP T P P+P P P +P
Sbjct: 557 TKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTT----------PKEPAPTTTKKPAPTTP 605
Query: 1042 KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPK 1101
K P T+P++T T + +++P+T E L T+ + +P +L + P
Sbjct: 606 KEPAP-TTPKETAPTTPK-------KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAK---------SHNSPHGCQSAHEKGLKTRLPVGLKV 1152
P+ E P+ +++ ++P + + +P K P G
Sbjct: 658 PT---TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG--- 711
Query: 1153 LMKSPQLLRK-SSTVPGK-HEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
+P L++ + T P K K+ +K + KP + + T E T
Sbjct: 712 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
P A + P T L+EP ++ P + + + S++ P
Sbjct: 770 PKEPAPTTPKGTAP--TTLKEPAPTT-PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 1271 AKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAP 1330
A + + KP+ E +++ T T + T S ES+P + + P
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTP-ELSAEP 884
Query: 1331 MLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA 1390
++L + + G P++ + ++ ++ LR P E P + A
Sbjct: 885 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKETA 942
Query: 1391 FTQGECPSANVAVLGEPGSDRRSCPPTP---TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
T + + + + + TP T +P T T T+
Sbjct: 943 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 1002
Query: 1448 SGRHPDASATATDAVS------SEAPLSPTIEEK 1475
P AT + A + ++AP PT +K
Sbjct: 1003 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 1036
Score = 64.3 bits (155), Expect = 1e-09
Identities = 183/959 (19%), Positives = 324/959 (33%), Gaps = 144/959 (15%)
Query: 735 SEEDTEKNIPKDNVDNVPRVSTESFSS--------RTVTQNPQQQKLVKPTHNISCQSNS 786
SEE TE++ +N ++ S+ S SS + N + QK +K N ++
Sbjct: 151 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 210
Query: 787 RSSAPMGIYQKQNLT------KIPPRGKSSPQKSKLM-EPEATTLLPSSGLVTL------ 833
+ + + + K+ S+ Q +K+ P+ TT P + +L
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270
Query: 834 EKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPK---S 890
K +L K + E++ + +D SA+ S S +D K
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 891 QTPGSRSR---PAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDY 947
TP + + PA+ + P T E + P K P+P ++ + P+
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTP----KEPTP-------TTIKSAPTTPK 379
Query: 948 SPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTH 1007
PAP++TKS P E A T K P AP PA T + P+ P
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEP------APTTPKEPAPTTTKEPAPTTTKSAP---- 429
Query: 1008 PMPSPEAVIQTRCPA-HAPSSSFTVMALGPPKVSPKRGVPKT-SPRQTLGTPQRDIGLQT 1065
P A + PA P P +PK P T P T TP+
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT--TPKEPAPTAP 487
Query: 1066 PRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPA 1125
+ +P+T + T+ K +P + S +TP +P +P++ S+ +++ PA
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEP-------APTTTKSAPTTTKEPA 538
Query: 1126 KSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAV 1185
+ T+ P +P +K + K E +
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTT 597
Query: 1186 NKSKPEDSKNPA-------------SMEITAGERNV-TLPDSQAQGSLADGLPLETALQE 1231
K P K PA + T E+ T P+ A + + P
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 1232 PLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKA--RSHSFSTHSGDKPST- 1288
P P + + ++ P A + + +T G P+T
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1289 ---PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHP 1345
P ++ T + S T + + AP+ P + + P+ P
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--P 775
Query: 1346 SSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLG 1405
++ KG+ ++ K P PK P KE T+G P++ +
Sbjct: 776 TTPKGTAPTT----------LKEPAPTTPKK-----PAPKELAPTTTKG--PTSTTSDKP 818
Query: 1406 EPGSDRRSCPPTPTD-CPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSS 1464
P + + + P TP + P + P T + T+S T+ + P + D +
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 1465 EAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRK 1524
E PT P ++E K G ++ PA + K
Sbjct: 879 ELSAEPT---------------------PKALENSPKEP-------GVPTTKTPA--ATK 908
Query: 1525 MDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQS 1584
+++ T +K R L++ + P++ ET K T+S +
Sbjct: 909 PEMTTTAKDKTT-------ERDLRTTPETTTAAPKMTKETATTTEKTTESKIT---ATTT 958
Query: 1585 KNNRRTPQDI--YNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNAS 1641
+ T QD + ++ V + K TE++N+ ++ A P+ + +S A+
Sbjct: 959 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 1017
Score = 45.8 bits (107), Expect = 4e-04
Identities = 111/587 (18%), Positives = 185/587 (31%), Gaps = 72/587 (12%)
Query: 910 PTRDEHCGS--GPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTK------------ 955
P + C P + S PPP G S ++ + + SP P + K
Sbjct: 98 PDYESFCAEVHNPTSPPSSKKAPPPSGASQTI--KSTTKRSPKPPNKKKTKKVIESEEIT 155
Query: 956 -----SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMP 1010
SE + S ++ + S ++ I + S N A +KK V K T P
Sbjct: 156 EEHSVSENQESSSSSSSSSSSSTIRKIKS---SKNSAANRELQKKLKVKDNKKNRTKKKP 212
Query: 1011 SPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISP 1070
+P+ + + + F V P + + TSP+ T P P
Sbjct: 213 TPKPPVVDEAGSGLDNGDFKVTT--PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270
Query: 1071 STHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS 1130
S L + +V N ST K E+ S + +S+ + +K
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 1131 PHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKP 1190
P KG P K P + T P + + E + +++ KS P
Sbjct: 331 PTPKAETTTKGPALTTP-------KEP-----TPTTPKEPASTTPKEPTPTTI---KSAP 375
Query: 1191 EDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRS 1250
K PA T + T P A + + P P + P
Sbjct: 376 TTPKEPAP---TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 1251 MRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGN 1310
+ ++ K KPA +T P+TP T T +
Sbjct: 433 KEPAPTTPK---KPAP------------TTPKEPAPTTPKEP----------TPTTPKEP 467
Query: 1311 SLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPL 1370
+ T + + + AP+AP + + P+ P++ K ++ S P
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTKEPSPTTPKEPAPT 525
Query: 1371 RIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTD-CPEALQSPG 1429
P + A T + PS P + + P TP P + P
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 1430 RTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKV 1476
T T++ T+ + P + A ++ L+PT EK+
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Score = 35.0 bits (79), Expect = 0.70
Identities = 96/461 (20%), Positives = 150/461 (32%), Gaps = 71/461 (15%)
Query: 1073 HEPLEMTSSKSVSP--GRKGQLNDSASTPPKP-----------SFLGVNESPSSQVSSSS 1119
H P SSK P G + + PKP S E S+ SS
Sbjct: 108 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 167
Query: 1120 SSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SSSS + S ++ +S+ L LKV KD+ +
Sbjct: 168 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-------------------KDNKKNRT 208
Query: 1180 KSSVAVNKSKPEDS-KNPASMEITAGERNVTLPD-SQAQGSLADGLPLETALQ--EPLES 1235
K K P+ + A + G+ VT PD S Q + P T + P S
Sbjct: 209 K-----KKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 263
Query: 1236 SIPGSDGRDGVDNRSMRRSLSSSK--PHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEG 1293
P SD + + +K +G + + + T S +K S +
Sbjct: 264 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 323
Query: 1294 SGKVRTQII--TNTAERGNSLTRQNSSTESSPNKAPSAPMLESLP-SVGRPSGHPSSGKG 1350
+ KV + T +G +LT T ++P + S E P ++ P
Sbjct: 324 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 1351 SLGSSGSFSSQHGSP--SKLPLRIPPKSEGLLI---PPGKEDQQAFTQGECPSANVAVLG 1405
+ S + + +P +K P PK P + A T + P+
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 1406 EPGSDRRSCPPTPTD-CPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSS 1464
P + + P TP + P + P P+T E + T+ E + P A T
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPAPTAPKKPAPTTP--KE 497
Query: 1465 EAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPS 1505
AP +P E TK S ++P P+
Sbjct: 498 PAPTTPK-------------EPAPTTTKEPSPTTPKEPAPT 525
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 70.5 bits (171), Expect = 2e-11
Identities = 108/530 (20%), Positives = 201/530 (37%), Gaps = 58/530 (10%)
Query: 878 MPSRRDWVQCPKSQTPGSRSRPAIESSDSG-EPPTRDEHCGSGPEAGVKSPSPPPPPGRS 936
+P++R + K+ S S + ESSD E + + G + K+ PP +S
Sbjct: 107 VPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKS 166
Query: 937 VSLLARPSYDYSP--------APSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPAT 988
+ S + P P + K++T+ P + AR K K S+ SS+ ++
Sbjct: 167 SDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226
Query: 989 TEVQRKKPSVAFKKPIFTHPM-----PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKR 1043
++ ++ + A K P A TR + + SS + K
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 1044 GVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLE----------MTSSKSVSPGRKGQLN 1093
G + P + P++ +G Q P+ + +P+E +S + P K ++
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVS 346
Query: 1094 DSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLP-VGLKV 1152
+ + PP + S SS SS +P+K + S+++ + T+ P V
Sbjct: 347 KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK--NSSNKPAVTTKSPAVKPAA 404
Query: 1153 LMKSP-----QLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERN 1207
K P +LL + + E+ S +E K+ V +KP+ + A
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAA---------- 454
Query: 1208 VTLPDSQA-QGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPAL 1266
++LP QA QGS +++ E E + V + + ++ KPA
Sbjct: 455 LSLPAKQAPQGSRDSSSDSDSSSSEEEEE----KTSKSAVKKKPQK--VAGGAAPSKPAS 508
Query: 1267 GMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQN-----SSTES 1321
G S+S S+ + ++G G R Q A ++LT QN +S E
Sbjct: 509 AKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQ--APKANGTSALTAQNGKAAKNSEEE 566
Query: 1322 SPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLR 1371
K +A ++ S+ + + ++ + + Q +P+ P R
Sbjct: 567 EEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQ--TPNTFPKR 614
Score = 32.7 bits (73), Expect = 3.5
Identities = 108/560 (19%), Positives = 191/560 (34%), Gaps = 77/560 (13%)
Query: 1307 ERGNSLTRQNSSTESSPNKAPSAPMLESLPS--VGRPSGHPSSGKGSLGSSGSFSSQHGS 1364
++ +S ++SS E + P A ++P+ VG P G ++ K S SS SS
Sbjct: 80 KKASSSDSEDSSEEEEEVQGPPAKKA-AVPAKRVGLPPGK-AAAKASESSSSEESSDDDD 137
Query: 1365 PS---KLPLR--IPPKSEGLLIPPGK-----EDQQAFTQGECP-SANVAVLGEPGSDRRS 1413
K P++ + P+++ PP K D + ++ E P + + +
Sbjct: 138 EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTK 197
Query: 1414 CPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATAT---DAVSSEAPL-- 1468
PP P + + G+ S+ +SS+S ++ A+ T V ++AP+
Sbjct: 198 APPKPARAAPKIAN-GKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKA 256
Query: 1469 SPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDIS 1528
+ T K + ++ + Q KP K KPGP + S P S
Sbjct: 257 ATTPTRKSSSSEDSSSDEEEEQKKPM----KNKPGPYSSVP---PPSAPPPKKSLGTQPP 309
Query: 1529 KTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNR 1588
K VEK+ + +E+KKP + K + + S ++
Sbjct: 310 KKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSD 369
Query: 1589 RTPQDIYNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKG 1648
+ D P S+ +T V AAP+ G + +L
Sbjct: 370 SSEDDE------APSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG----QKLLTR 419
Query: 1649 SSQGSCLIGSSISTQGNHKKNM----KIKADMEVPKDSLVKEANENLQEDEDDAVADSVF 1704
+ S S S++ K M K KA + K+A + ++ D+ + S
Sbjct: 420 KADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE 479
Query: 1705 QSHIIESNCQMRTLDSGIGTFPLPDS------GNRSTGRYLCQPDSPEDAEPLL------ 1752
+ S ++ + P G + DS E+ E L
Sbjct: 480 EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP 539
Query: 1753 -PLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKP 1811
P + S++ AQ + S + + +A+V S
Sbjct: 540 RPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVS--------------------- 578
Query: 1812 ASSGKVSSQKQNEAEPRPQT 1831
SG + +KQNEA +T
Sbjct: 579 -KSGSLKKRKQNEAAKEAET 597
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 67.4 bits (163), Expect = 1e-10
Identities = 71/301 (23%), Positives = 141/301 (46%), Gaps = 47/301 (15%)
Query: 18 LDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQ-----RTSEGAMHEK 72
L L E + + + L ++E + W + +LQ+E+A RTS + +
Sbjct: 918 LSEKLKEESEQKEQLRRLKNEMENER---WHLGKTIEKLQKEMADIVEASRTSTLELQNQ 974
Query: 73 LIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQK 132
L E+ R + +++L+E TLE+E++R+ +Q + MEE +R+ ++Q K
Sbjct: 975 LDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 1034
Query: 133 K---EETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERL 189
+ E+T+ + Y+ + + + L + + D+ S+ E +E + + LL ER+
Sbjct: 1035 RQLLEQTLKDLEYELEAKSHLKDDRSRL--VKQMEDKVSQLE-MELEEERNNSDLLSERI 1091
Query: 190 KALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQN 249
REQ ++++ N+++Q ++DL EC K+ LE+QN
Sbjct: 1092 --------------SRSREQ----MEQLRNELLQERAARQDL--ECDKI-----SLERQN 1126
Query: 250 RTLS---ILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRS---LTQSRTDAEVH 303
+ L I + R + + L+ ++ +R+ +L D L ER+R+ L+ R + +V
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELE--DRLESEERDRANLQLSNRRLERKVK 1184
Query: 304 E 304
E
Sbjct: 1185 E 1185
Score = 44.3 bits (103), Expect = 0.001
Identities = 98/463 (21%), Positives = 179/463 (38%), Gaps = 74/463 (15%)
Query: 74 IHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQ----SQGSP 129
+ EL+ + L +++++ ++E E ER R + L+ Q + E L Q S+G
Sbjct: 623 VAELQRQLQLEVKNQQNIKE---ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 130 EQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDE------------ 177
+ EE + + +E+ E R ++ L ++H +D RSE
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 178 -----GKEKTKLLLERLK--------ALEAENSALALENENQREQYERCLD------EVA 218
KE+ + LL + + AL+ E S+ E + +EQY+ L E A
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 799
Query: 219 NQVVQALLTQKDLRE-ECVKLKTRVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLD 277
+ V+ L ++ + E + + RV L+++N L ++ R + L Q + +
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDE 859
Query: 278 LSSGDLLSEVERN-RSLTQSRTDAEVHEHQ-LNTKSALKCPGLGAVIPGHLCPRNSYSSS 335
+ + L + E R L ++ A E + ++ + AL+ A G+L S ++
Sbjct: 860 AKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAA--QGNL----SQTTQ 913
Query: 336 SELSLSSTCSEYSSG-----------SSYTWHDGKNLRKRQSSQNWDKRLSIDSSLPSGF 384
+ LS E S + WH GK + K Q S S+L
Sbjct: 914 EQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL---- 969
Query: 385 ASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSVITKWGYKDCMNSNEGIYSPGIKSS 444
N+L + K L +++ K K L S +T +D M +
Sbjct: 970 -ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR---------LMEE 1019
Query: 445 SLKEYPPCKTADLGSP--CKEPHKTFVYDLDSHVDADDDPSTL 485
L++Y + L ++ K Y+L++ DD S L
Sbjct: 1020 ELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRL 1062
Score = 33.5 bits (75), Expect = 2.0
Identities = 38/168 (22%), Positives = 78/168 (46%), Gaps = 25/168 (14%)
Query: 134 EETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALE 193
+ T +++ Q++L+++ + + A + L+ + E S +T K K L+ E+++ L+
Sbjct: 534 QATPDLLKGQQELTQQTNE-ETAKQILYNYLKEGSTDNDDAT---KRKVNLVFEKIQTLK 589
Query: 194 AENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLS 253
+ + A N NQ + KDL E+ KL V +L++Q + L
Sbjct: 590 SRAAGSAQGN---------------NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQ-LE 633
Query: 254 ILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDAE 301
+ QQ ++ +++ + L +L S +VE N +L Q ++E
Sbjct: 634 VKNQQNIKEER----ERMRANLEELRS-QHNEKVEENSTLQQRLEESE 676
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 65.5 bits (158), Expect = 5e-10
Identities = 223/1071 (20%), Positives = 353/1071 (32%), Gaps = 181/1071 (16%)
Query: 490 AVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEK---------LTSC 540
A P +S P G T + S + T FLEGT S+ PK P K + +
Sbjct: 647 AFPLESADPAGVAPTTAKGTSTY--TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 541 ASSCPLE------------MKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETF 588
+ +CP+ + L P + P G G ++ + T
Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD------GISHTS 758
Query: 589 DELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVP--------- 639
+ SS ++ P++ S A+ T S L L L S + K+ P
Sbjct: 759 ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 640 -----IPSETRPKTFSFIKQQRVVKRTSSEECVTVIFD---AEDGEP------------I 679
+ S P SF+ + + + S + T + G P +
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878
Query: 680 EFSSHQTGVVTVT--------------RNEISINSTPAGPKAEHTELLPQGI-ACLQPRA 724
+T +V + +++ T + PK P+GI A P+
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 725 AARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQS 784
A S + P + S T +P+ S +
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
Query: 785 NSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKL 844
+ +P G +T PP K SP + P+ + P++ + + SPA P L
Sbjct: 999 GPATPSPKGAPTPPAVT--PPSPKGSPAATPF--PKGASTPPAATPPSPKGSPAATP--L 1052
Query: 845 SRFMKTESSGPLFELRSDPHIPK-HSAQLPHSSRMPSRRDW--VQCPKSQTPGSRSRPAI 901
+ T + L + P P A P ++ PS + PK + P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 902 ESSDSGEPPTRDEHCGSGPEAGVKSPSP------PPPPGRSVSLLARPSYDYSPAPS--- 952
PP H G+ PSP PPP G + A P P+P
Sbjct: 1113 PKGGLATPP----HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-----PSPKGGL 1163
Query: 953 STKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKP----IFTHP 1008
+T P+ A TP SP G++ P P T P P T P
Sbjct: 1164 ATPPPKGAPTTPAATP-PSPK-GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
Query: 1009 M---PSPEAVIQTRCPAHAPSSSFTV--MALGPPKVSPKRGVPKTSPRQT-------LGT 1056
PSP+ + T P AP++ G P P +G P T P T L T
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-TPPAATPPSLKGGLAT 1280
Query: 1057 PQRD-------IGLQTPRISPSTHEPLEMTS-------SKSVSPGR---KGQLNDSASTP 1099
P + +P+ P+T P + S SPG KG A TP
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 1100 PKPSFLGVNESPSSQVSSSSSSSSPA-KSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQ 1158
P P G P++ SS ++P+ K +P +H+ G P SP+
Sbjct: 1341 PSPK--GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP--------SPK 1390
Query: 1159 LLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITA-GERNVTLPDSQAQG 1217
+ G ++ S E + P+ ++T V+L + A
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 1218 SLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHS 1277
+ G ++ +P ++ ++ + + S S K PA GA
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA--PMGAPTLPAV 1508
Query: 1278 FSTHSGDKPSTP-----PIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPML 1332
+ + P+TP PI + + ++ T +L + T SP K P+ P
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP-AMTVPSPKKTPAIPTP 1567
Query: 1333 ESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFT 1392
+ P+ PSS + S + + S+ G+PS L IPP + P KE
Sbjct: 1568 KEAPAT------PSSKEASSPPAVTPSTYKGAPSPKELLIPP---AVTSPSPKE------ 1612
Query: 1393 QGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTS 1443
+ + P ++ P P P SP T PS+ + S TS
Sbjct: 1613 -----APTPPAVTPPSPEKGPATPAPKGTP---TSPPVT--PSSLKDSPTS 1653
Score = 62.0 bits (149), Expect = 5e-09
Identities = 162/707 (22%), Positives = 242/707 (34%), Gaps = 121/707 (17%)
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDP 863
PP+G +P P+ T LP++ +P+ G + K + P
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPAT-------TPSSKGGPTTPSSKEGPTPPAAT----- 1375
Query: 864 HIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAG 923
P H + P R + PK P P TR+ G
Sbjct: 1376 --PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE---------G 1424
Query: 924 VKSPSP---PPPPGRSVSLLARPSYDY---SPAPSSTKSETRVPSETARTPFKSPLLKGI 977
+PS PP VSL P+ PA S+K + +P+ T +P + P K +
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 978 SAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPS-------PEAVIQTRCPAHAPSSSFT 1030
+ T P++ P +P+ P A T P++
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544
Query: 1031 VMALGPPKV---SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHE----PLEMTSSKS 1083
AL PP + SPK+ +P++ TP P ++PST++ P E+ +
Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA 1604
Query: 1084 V-SPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGL 1142
V SP K A TPP P +P+ + + +S +P+ +SP S K +
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPE--KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK-M 1661
Query: 1143 KTRLPVGLKVL--MKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME 1200
+P K L K P L++ P E++ A + P+ K+ A+
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAP-------ESTPIITAPTRKGPQTKKSSATSP 1714
Query: 1201 ITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKP 1260
PD A+ PL T PL L K
Sbjct: 1715 -------PICPDPSAKNGSKG--PLSTVAPAPL---------------------LPVQKD 1744
Query: 1261 HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE 1320
K A G + ++HS P PP K T + E+ L + S++
Sbjct: 1745 SSKTAKGKD---------ASHSPKGPLAPP---ESKASTPLTAAAFEK--VLPKPESASV 1790
Query: 1321 SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGL- 1379
S+ APS P+ SLP P + L SS + SPSK PL + E L
Sbjct: 1791 SA---APSPPV--SLPLAPSPVPTLPPKQQFLPSSPGLVLE--SPSK-PLAPADEDELLP 1842
Query: 1380 LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFET 1439
LIPP G P +V V + + + P PT P A Q + S E+
Sbjct: 1843 LIPPEP------ISGGVPFQSVLV--NMPTPKSAGIPVPT--PSAKQPVTKNNKGSGTES 1892
Query: 1440 SSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEK 1486
S + AT A + A + EE V Q EK
Sbjct: 1893 DSDESVPELEEQDSTQATTQQAQLAAA--AEIDEEPVSKAKQSRSEK 1937
Score = 56.2 bits (134), Expect = 3e-07
Identities = 176/758 (23%), Positives = 257/758 (33%), Gaps = 135/758 (17%)
Query: 763 TVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEAT 822
T ++P LV+ S S SS+P +IP +++ K L EP
Sbjct: 552 TTKKDPTVLPLVQAAPKNSPSFQSTSSSP----------EIPLSPEATLAKKSLGEPLPI 601
Query: 823 TLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRR 882
SS L + + + K + +S+GPL L+S P +A P S P+
Sbjct: 602 GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPL--LKSSLITPTVAA-FPLESADPAGV 658
Query: 883 DWVQCPKSQTPGSRSRPAIESSDSGEP----------------PTRDEHCGSGPEA---- 922
+ T + + P +E + S P PT E+C P
Sbjct: 659 APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
Query: 923 --------------GVKSPSPPP---PPG-RSVSLLARPSYDYSPAPSSTK---SETRVP 961
V SPS PP PPG + V ++ S +P SS K +E
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSA-LAPVASSPKECPTEDSGA 777
Query: 962 SETARTPFKSPLLKGISAPV-ISSNPATTEVQRKKPSVAFKKPI--FTHPMPSPEAVI-- 1016
S TA + L +P+ +S +P T KK S PI + P+ EA
Sbjct: 778 SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLP 837
Query: 1017 ----------QTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTP 1066
+ H+P+ A P V+P T P + TP + L P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV-VNLPFP 896
Query: 1067 RISPSTHEP-----LEMTSSKS-------------VSPGRKGQLNDSASTPPKPSFLGVN 1108
+ P+T P L MTSS SP KG A+TPP P G
Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK--GGP 954
Query: 1109 ESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPG 1168
+PS + + + +++P SP G G T P G +P + P
Sbjct: 955 ATPSPKWAPTPPAATPP----SPKG-------GPATPSPKG------APTPPAATPPSPK 997
Query: 1169 KHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERN---VTLPD---SQAQGSLADG 1222
+ + + AV P+ S PA+ G T P S A L G
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 1223 LPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPAL-GMNGAKARSHSFSTH 1281
P A P P + G + + P PA GA +
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPP---AATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 1282 SGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPM--LESLPSVG 1339
+TPP +G+ T T + +G T ++P P +P L + P G
Sbjct: 1113 PKGGLATPPHKGA--PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 1340 ---RPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGEC 1396
P+ P S KG L + S G+P+ P PP +G L P + T
Sbjct: 1171 APTTPAATPPSPKGGLAT----PSPKGAPT-TPAATPPSPKGGLATPSPKGAPT-TPAAT 1224
Query: 1397 PSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHP 1434
P + L P + P TP P + + T P
Sbjct: 1225 PPSPKGGLATPSP--KGAPTTPAATPPSPKGGPATPPP 1260
Score = 42.4 bits (98), Expect = 0.004
Identities = 172/791 (21%), Positives = 272/791 (34%), Gaps = 148/791 (18%)
Query: 744 PKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKI 803
PK N++ VP +E + T +P P H ++ ++ +S + Q T +
Sbjct: 184 PKTNLNKVP---SEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA-SLPQTTPTTTL 239
Query: 804 P---PRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTE-SSGPLFEL 859
P+ K + S L+ P+ L G V+ + +L+ L ++ ++GP
Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGP---- 295
Query: 860 RSDPHIP----KHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEH 915
+ P P H A L H S S VQ P + S P +++ +H
Sbjct: 296 NTPPDFPISLGSHLAPL-HQSSFGS----VQLLGQTGPSALSDPTVKTISV-------DH 343
Query: 916 CGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLK 975
+G + PP P R+ + A + APS K + + S T SP
Sbjct: 344 SSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITC-----SPSGS 398
Query: 976 GISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMP------SPEAVIQTRCPAHAPSSSF 1029
A S +P T+ + + P+ + P+ MP +P V A AP+++F
Sbjct: 399 LNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-MPVSSVGTTPLVVTNPCTIAAAPTTTF 457
Query: 1030 TVMALGPPKVS--PKRGVPKTSPRQTLGTP--------QRDIGLQTPRISPSTHEPLEMT 1079
V P +S P + TSP + P Q L+ P +SP +P ++
Sbjct: 458 EVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIP-VSPPLPDPEDLK 516
Query: 1080 SSKSVS----PGRKGQLNDSAS---TPPKPSFLG------------VNESPSSQVSSSSS 1120
+ S P +K AS P P+ G V +P + S S+
Sbjct: 517 NLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST 576
Query: 1121 SSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVL-MKSPQLLRKSSTVPGKHE---KDSLN 1176
SSSP + SP + +K L LP+G M SP + S++V DS
Sbjct: 577 SSSP-EIPLSPEATLA--KKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
Query: 1177 EASKSSVAVNK--SKPEDSKNPASMEITAGERNVTLPDSQA-----------------QG 1217
KSS+ + P +S +PA + T + T + + +G
Sbjct: 634 PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEG 693
Query: 1218 SLADGLPLETALQE---------------------------------PLESSIPGSDGRD 1244
+L LPL E P + PG+ D
Sbjct: 694 TLTT-LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD 752
Query: 1245 GVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITN 1304
G+ + S ++SS A A S T+ D PS + S + + + T
Sbjct: 753 GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK-RPPTK 811
Query: 1305 TAERGNSLTRQNSSTESSPNKA-------------PSAPMLESLPSVGRPSGHPS-SGKG 1350
G N S+ SP +A +P P+ P G P+ S
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
Query: 1351 SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPS---ANVAVLGEP 1407
L G +P+ + +P EG P K+ P A A G P
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 1408 GSDRRSCPPTP 1418
S PTP
Sbjct: 932 ASPSPKGAPTP 942
Score = 38.9 bits (89), Expect = 0.049
Identities = 129/613 (21%), Positives = 207/613 (33%), Gaps = 83/613 (13%)
Query: 918 SGPEAGVKSPSPPPPPGRSVSLLAR--------PSYDYSPAPSST-------KSETRVPS 962
+ P A V +P P P V+ R D PSS K VP+
Sbjct: 478 TSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPA 537
Query: 963 ETARTPFKSPLLKGISAPVISSNPATTEVQRKKP--SVAFKKPIFTHPMP-SPEAVIQTR 1019
PF SP G++ +P + + P S +F+ + +P SPEA + +
Sbjct: 538 SLEGAPF-SPAQAGLTT---KKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 1020 C-----PAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHE 1074
P P+SS T P V+ V KT G L++ I+P+
Sbjct: 594 SLGEPLPIGKPASSMT----SPLGVNSSASVIKTD--SYAGPDSAGPLLKSSLITPTVAA 647
Query: 1075 -PLEMTSSKSVSPGR-KGQLNDSASTPP---KPSFLGVNESPSSQVSSSSSSSSPAKSHN 1129
PLE V+P KG + + P L P + + ++ P S N
Sbjct: 648 FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707
Query: 1130 SPHGCQSAHEKGLKTRLPVGLKVLMKSPQ-LLRKSSTVPGKHEKDSLNEASKSSVAVNKS 1188
P + L + ++ P L + T PG + D ++ S + +
Sbjct: 708 CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP 767
Query: 1189 KPEDSKNPASMEITAGERNVT-LPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVD 1247
K +++ + + + +T L DS + PL ++ P P G G D
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPS--------PLGVSVS-PQTKRPPTKKGSAGPD 818
Query: 1248 NR--SMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPS-----TP----PIEGSG- 1295
++ +S + P ++ ++ +THS PS TP P+ G
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878
Query: 1296 -----KVRTQIITNT-------AERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSG 1343
+ T + N A S T SSP KA + P + +P+ P G
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 1344 HPSSGKGSLGS---SGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSAN 1400
P+ + S + S +P+ P PP +G P + PS
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTP-PAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997
Query: 1401 VAVLGEPGSDRRSCPPTP--TDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATA 1458
G P + PTP P SP T P T + + P A+
Sbjct: 998 ----GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 1459 TDAVSSEAPLSPT 1471
A ++ A P+
Sbjct: 1054 KGAPTTPAATLPS 1066
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 65.1 bits (157), Expect = 6e-10
Identities = 149/687 (21%), Positives = 241/687 (35%), Gaps = 85/687 (12%)
Query: 819 PEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHI---PKHSAQLPHS 875
PE+TT S G L P + E+S P+ PH P S
Sbjct: 1773 PESTTFHSSPG----STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGE 1828
Query: 876 SRM----PSRRDWVQCPKSQTPG-----------SRSRPAIESSDSGEPPTRDEHCGSGP 920
S PS +D + P + T S P S S R E +
Sbjct: 1829 STTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 1888
Query: 921 EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETAR-TPFKSPLLKGISA 979
+ V + + P P + S L S Y +P ST++ S TA +S +
Sbjct: 1889 SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 1948
Query: 980 PVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKV 1039
ISS P+TT ++P+ P T P++ + + +S + A G V
Sbjct: 1949 HTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG-TIV 2007
Query: 1040 SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTP 1099
P R ++ +P ++T + ST +PG + S+P
Sbjct: 2008 LPARSTTSVLLGESTTSPISSGSMETTALPGST-----------TTPGLSEKSTTFHSSP 2056
Query: 1100 PKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQL 1159
P+ SP+S SS S S SH+ P S H T P +P L
Sbjct: 2057 RSPA---TTLSPASTTSSGVSEES-TTSHSRP---GSTH----TTAFPDS----TTTPGL 2101
Query: 1160 LRKSST---VPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQ 1216
R S+T PG + +L AS ++ ++ +P S + + T +
Sbjct: 2102 SRHSTTSHSSPGSTD-TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE 2160
Query: 1217 GSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPH--LKPALGMN-GAKA 1273
+ P T + P S G+ S R S+ P L PA + G +
Sbjct: 2161 STTFHSSPGSTH-----TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 2215
Query: 1274 RSHSFSTHSGDKPST--PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPM 1331
S +F TH +T PP + V + T G++ T ++ ++ + + +
Sbjct: 2216 ESTAFQTHPASTHTTPSPPSTATAPVE-ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 2274
Query: 1332 LESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA- 1390
S P + PSS + G ++ SP + P G PG +
Sbjct: 2275 FHSSPDASGTT--PSSAHSTTSGRGESTTSRISPGSTEITTLP---GSTTTPGLSEASTT 2329
Query: 1391 -FTQGECPSANVAV-------LGEPGSDRRSCPPT--PTDCPEALQSPGRTQHPSTFETS 1440
++ P+ ++ +GE + RS P + T P + +PG ++ +T +S
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 2389
Query: 1441 STSKLETSGRHPDASATATDAVSSEAP 1467
S ET+ T T +V E P
Sbjct: 2390 SPGSTETT----VFPRTPTTSVRGEEP 2412
Score = 62.0 bits (149), Expect = 5e-09
Identities = 185/867 (21%), Positives = 283/867 (32%), Gaps = 129/867 (14%)
Query: 682 SSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEK 741
+SH + T T + S +ST G E T + +A + AR T E
Sbjct: 1858 TSHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH 1916
Query: 742 NIP-KDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNL 800
+ P + P ST S S + TH IS ++ S+ L
Sbjct: 1917 SSPGSTQTMHFPESSTASGRSEESRTSHSST-----THTISSPPSTTSA----------L 1961
Query: 801 TKIPPRGKSSPQKSKLME-PEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFEL 859
+ P SSP + P+++T S T S A G + ++ +S L E
Sbjct: 1962 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 2021
Query: 860 RSDPHIP--KHSAQLPHSSRMP--SRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEH 915
+ P + LP S+ P S + ++P + PA +S + H
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 2081
Query: 916 CGSGPEAGVKSPSPPPPPGRS----VSLLARPSYDYSPAPSSTKSETRVPSETARTPFKS 971
G P PG S S + S D + P+ST T PS+ + T S
Sbjct: 2082 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT--TSGPSQESTTSHSS 2139
Query: 972 PLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTV 1031
P S S +TT + + S F SP + T P SS
Sbjct: 2140 PG----STDTALSPGSTTALSFGQESTTFHS--------SPGSTHTTLFPDSTTSSGIVE 2187
Query: 1032 MALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQ 1091
+ +V G P+T+ T GLQ + TH P ++ S
Sbjct: 2188 AST---RVHSSTGSPRTTLSPASSTSP---GLQGESTAFQTH-PASTHTTPSPPSTATAP 2240
Query: 1092 LNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLK 1151
+ +S + P P+S +S S S H+SP + T G
Sbjct: 2241 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI-FHSSPDASGTTPSSAHSTTSGRGES 2299
Query: 1152 VLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASM-EITAGERNVTL 1210
+ + +T+PG L+EAS + + +S P + +PASM + GE + T
Sbjct: 2300 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS-PTTTLSPASMTSLGVGEESTT- 2357
Query: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
S PGS S S P L
Sbjct: 2358 -----------------------SRSQPGST-----------HSTVSPASTTTPGLSEES 2383
Query: 1271 AKARSHS-FSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA 1329
S S ST + P TP G+ T + A +L ++S+T ++ +
Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAF 2443
Query: 1330 PMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQ 1389
P + G P+ ++ G S +F S G S G + P +
Sbjct: 2444 PGSPASTQTGLPATLTTADLGE--ESTTFPSSSG------------STGTTLSPARSTTS 2489
Query: 1390 AFTQGECPSANVAVLGEPGSDRRSCPPTPTD---------------CPEALQSPGRTQHP 1434
PS L ++ + P +PT P+A SP T
Sbjct: 2490 GLVGESTPSR----LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 2545
Query: 1435 STFETSSTSKLETSGRH----PDASAT------ATDAVSSEAPLSPTIEEKVMLCIQENV 1484
E SSTS + H PD++ T +T + SS T+ +
Sbjct: 2546 GVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQ 2605
Query: 1485 EKGQVQTKPTSVEAKQKPGPSFASWFG 1511
E + P S + PG + A FG
Sbjct: 2606 ESTTSHSSPGSTDTALSPGSTTALSFG 2632
Score = 61.2 bits (147), Expect = 9e-09
Identities = 144/674 (21%), Positives = 235/674 (34%), Gaps = 93/674 (13%)
Query: 819 PEATTLL--PSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHI---PKHSAQLP 873
PE+TT P S TL A G L E+S P+ PH P S
Sbjct: 3330 PESTTFHSGPGSTETTLLPDNTTASGLL------EASTPVHSSTGSPHTTLSPAGSTTRQ 3383
Query: 874 HSSRM----PSRRDWVQCPKSQTPG-----------SRSRPAIESSDSGEPPTRDEHCGS 918
S P+ +D P + T S P S S R E +
Sbjct: 3384 GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 3443
Query: 919 GPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSE-TARTPFKSPLLKGI 977
+ V + + P P + S L S Y +P ST++ S+ T+ +S
Sbjct: 3444 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 3503
Query: 978 SAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPP 1037
+ ISS P+TT ++P+ P T P++ + + +S + A G
Sbjct: 3504 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG-T 3562
Query: 1038 KVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSAS 1097
V P R ++ +P ++T + ST +PG + S
Sbjct: 3563 IVLPARSTTSVLLGESTTSPISSGSMETTALPGST-----------TTPGLSEKSTTFHS 3611
Query: 1098 TPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSP 1157
+P P+ SP+S SS S S SH+ P S H T P
Sbjct: 3612 SPRSPA---TTLSPASTTSSGVSEES-TTSHSRP---GSTH----TTAFP---------- 3650
Query: 1158 QLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQ--- 1214
S+T PG + + +S S + + +S E T + D+
Sbjct: 3651 ----DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP 3706
Query: 1215 -AQGSLADGLPLETALQEPLESS---IPGSDGRDGVDNRSMRRSLSSSKPH--LKPALGM 1268
+ +L+ G T P + P S G+ S R S+ P L PA
Sbjct: 3707 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 3766
Query: 1269 N-GAKARSHSFSTHSGDKPST--PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNK 1325
+ G + S +F TH +T PP + V + T G++ T ++ ++
Sbjct: 3767 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVE-ESTTYHRSPGSTPTTHFPASSTTSGH 3825
Query: 1326 APSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGK 1385
+ + + S P + PSS + G ++ SP + P G PG
Sbjct: 3826 SEKSTIFHSSPDASGTT--PSSAHSTTSGRGESTTSRISPGSTEITTLP---GSTTTPGL 3880
Query: 1386 EDQQA--FTQGECPSANVAV-------LGEPGSDRRSCPPT--PTDCPEALQSPGRTQHP 1434
+ ++ P+ ++ +GE + RS P + T P + +PG ++
Sbjct: 3881 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 3940
Query: 1435 STFETSSTSKLETS 1448
+T +SS ET+
Sbjct: 3941 TTVYSSSPGSTETT 3954
Score = 57.8 bits (138), Expect = 1e-07
Identities = 153/676 (22%), Positives = 230/676 (34%), Gaps = 97/676 (14%)
Query: 820 EATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPK--HSAQLPHSSR 877
E+TT SSG SPA ++ +SG + E P + LP S
Sbjct: 2466 ESTTFPSSSGSTGTTLSPA----------RSTTSGLVGESTPSRLSPSSTETTTLPGSPT 2515
Query: 878 MPSRRD----WVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPP 933
PS + + P+S P + PA +S + H G P P
Sbjct: 2516 TPSLSEKSTTFYTSPRS--PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTP 2573
Query: 934 GRS----VSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATT 989
G S S + S D + P+ST T PS+ + T SP S S +TT
Sbjct: 2574 GLSRHSTTSHSSPGSTDTTLLPASTT--TSGPSQESTTSHSSPG----STDTALSPGSTT 2627
Query: 990 EVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTS 1049
+ + S F SP + T P SS + +V G P+T+
Sbjct: 2628 ALSFGQESTTFHS--------SPGSTHTTLFPDSTTSSGIVEAST---RVHSSTGSPRTT 2676
Query: 1050 PRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNE 1109
T GLQ + TH P ++ S + +S + P
Sbjct: 2677 LSPASSTSP---GLQGESTTFQTH-PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 2732
Query: 1110 SPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGK 1169
P+S +S S S H+SP + T G + + +T+PG
Sbjct: 2733 FPASSTTSGHSEKSTI-FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2791
Query: 1170 HEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETAL 1229
L+EAS + + +S P + +PASM T SQ + + P T
Sbjct: 2792 TTTPGLSEASTTFYSSPRS-PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 2850
Query: 1230 QEPLE------SSIPGSDGRDGVDNRSMRRSLSSSKP---HLKPALGMNGAKARSHSFST 1280
E SS PGS V RS S+ +P H +PA ST
Sbjct: 2851 PGLSEESTTVYSSSPGST-ETTVFPRSTTTSVRGEEPTTFHSRPA-------------ST 2896
Query: 1281 HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA-PMLESLPSVG 1339
H T + T + + LT ++++ SP + P + +G
Sbjct: 2897 H-----------------TTLFTEDSTT-SGLTEESTAFPGSPASTQTGLPATLTTADLG 2938
Query: 1340 RPSGHPSSGKGSLGSSGSFSSQHGSP---SKLPLRIPPKSEGLLIPPGKEDQQAFTQGEC 1396
S S GS G++ S + S P R+ P S PG + ++
Sbjct: 2939 EESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE--- 2995
Query: 1397 PSANVAVLGEPGSDRRSCPPTPTDCPEALQ--SPGRTQHPSTFETSSTSKLETSGRHPDA 1454
+ P S + P T + S +Q ST T+ TSG +
Sbjct: 2996 --KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEP 3053
Query: 1455 SATATDAVSSEAPLSP 1470
+A+ + S+EA LSP
Sbjct: 3054 TASHSSQGSTEATLSP 3069
Score = 56.6 bits (135), Expect = 2e-07
Identities = 172/808 (21%), Positives = 281/808 (34%), Gaps = 117/808 (14%)
Query: 697 SINSTPAGPKAEHTELLPQGIACL-QPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVS 755
S ++TP+ P T +P ++ R ++ T F S ++ V + P +
Sbjct: 4229 SSDTTPSPPS---TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 4285
Query: 756 -TESFSSRTVTQNPQQQKLVKPTHNISCQSNSR--SSAPMGIYQKQNLTKIPPRGKS--- 809
T F +R+ T + P + S ++ + S+ G+ +K PR
Sbjct: 4286 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 4345
Query: 810 SPQK--SKLMEPEATTL--LPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHI 865
SP S + E+TT P S T S PG + SS + P
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGS 4405
Query: 866 PKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSG----EPPTRDEHCGSGPE 921
S+ P S+ S +PGS + + + E T P
Sbjct: 4406 TTASSLGPESTTFHS-----------SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 4454
Query: 922 AGVKSPSPPPPPGRSVSLLARP-SYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAP 980
+ G S + + P S D +PAP +T S E + T SP S P
Sbjct: 4455 TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF---VELSTTSHGSPS----STP 4507
Query: 981 VISSNPATTEVQRKKPSVAF-KKPIFTHPMPSP-----EAVIQTRCPAHAPSSSFTVMAL 1034
+ ++T + R + S P+ T PSP +++ H+ S M
Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567
Query: 1035 GPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPL-EMTSSKSVSPGRKGQLN 1093
+ RG T+ + T +PST L E +S SPG +
Sbjct: 4568 PESNTTSGRGEESTTSHSST--------THTISSAPSTTSALVEEPTSYHSSPGSTATTH 4619
Query: 1094 --DSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLK 1151
DS++T + S + ++S SS + P ++ G T P+
Sbjct: 4620 FPDSSTTSGR----------SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 4669
Query: 1152 VLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLP 1211
+ + L S+T PG EK + +S SS P + +S + E + T+
Sbjct: 4670 SMETTA--LPGSTTTPGLSEKSTTFHSSPSST------PTTHFSASSTTLGRSEESTTVH 4721
Query: 1212 DSQAQGSLADGLPLETALQ-EPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNG 1270
S P+ TA P S+ G + S + + P A G +
Sbjct: 4722 SS----------PVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 4771
Query: 1271 AKARSHSFSTHSGDKPSTPPIEGSGKVRTQI--------ITNTAERGNSLTRQNSSTESS 1322
SHS +TH+ S+PP S V I T +S T S ++
Sbjct: 4772 ESRTSHSSTTHT---ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTA 4828
Query: 1323 PNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIP 1382
+ +P + LP+ SG + S GS + S + P + KS +L
Sbjct: 4829 SHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTP-GLSAKST-ILYS 4886
Query: 1383 PGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSST 1442
+ Q + S++++ GEP S L S + H + F S+T
Sbjct: 4887 SSRSPDQTLSPASMTSSSIS--GEPTS---------------LYSQAESTHTTAFPASTT 4929
Query: 1443 SKLETSGRHPDASATATDAVSSEAPLSP 1470
TSG +++ + S+E LSP
Sbjct: 4930 ----TSGLSQESTTFHSKPGSTETTLSP 4953
Score = 53.1 bits (126), Expect = 2e-06
Identities = 160/723 (22%), Positives = 254/723 (35%), Gaps = 104/723 (14%)
Query: 777 THNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLME-PEATTLLPSSGLVTLEK 835
TH IS ++ S+ L + P SSP + P+++T S T
Sbjct: 865 THTISSAPSTTSA----------LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 914
Query: 836 SPALAPGKLSRFMKTESSGPLFELRSDPHIP--KHSAQLPHSSRMP--SRRDWVQCPKSQ 891
S A G + ++ +S L E + P + LP S+ P S R +
Sbjct: 915 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPR 974
Query: 892 TPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRS----VSLLARPSYDY 947
+P + PA +S + G P PG S S + S D
Sbjct: 975 SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 1034
Query: 948 SPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTH 1007
+ P+ST T PS+ + T S G + +S T ++ + P TH
Sbjct: 1035 TLLPASTT--TSGPSQESTTSHSS---SGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089
Query: 1008 PMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPR 1067
P++ +SS V A +V G P+T+ T GLQ
Sbjct: 1090 TTLFPDST----------TSSGIVEA--STRVHSSTGSPRTTLSPASSTSP---GLQGES 1134
Query: 1068 ISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKS 1127
+ TH P ++ S + +S + P P+S +S S S
Sbjct: 1135 TAFQTH-PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI-F 1192
Query: 1128 HNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNK 1187
H+SP + T G + + +T+PG L+EAS + + +
Sbjct: 1193 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 1252
Query: 1188 SKPEDSKNPASM-EITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGV 1246
S P + +PASM + GE + T S++Q + P ++ PG
Sbjct: 1253 S-PTTTLSPASMTSLGVGEESTT---SRSQPGSTH------STVSPASTTTPGLSEESTT 1302
Query: 1247 DNRSMRRSLSSSK-PHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNT 1305
S R S ++ PH S + S H G++P+T + T ++
Sbjct: 1303 VYSSSRGSTETTVFPH-------------STTTSVH-GEEPTTFHSRPASTHTTLFTEDS 1348
Query: 1306 AERGNSLTRQNSSTESSPNKAPSA-PMLESLPSVGRPSGHPSSGKGSLGS--SGSFSSQH 1362
G LT ++++ SP + P + +G S S GS G+ S + S+
Sbjct: 1349 TTSG--LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTS 1406
Query: 1363 GSPSK-LPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDC 1421
G + P R+ P S PG S L E + + P +P
Sbjct: 1407 GLVGESTPSRLSPSSTETTTLPG-------------SPTTPSLSEKSTTFYTSPRSP--- 1450
Query: 1422 PEALQSPGRTQHPSTFETSSTSKLETSGRH----PDASATA----------TDAVSSEAP 1467
+A SP T E SSTS + H PD++ T+ + S+EA
Sbjct: 1451 -DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 1468 LSP 1470
LSP
Sbjct: 1510 LSP 1512
Score = 49.3 bits (116), Expect = 4e-05
Identities = 150/692 (21%), Positives = 238/692 (34%), Gaps = 137/692 (19%)
Query: 888 PKSQTPGSRSRPA-IESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYD 946
P S PA + ++D GE T + P + + + P + S L S
Sbjct: 4001 PGSPASTQTGLPATLTTADLGEEST------TFPSSSGSTGTKLSPARSTTSGLVGESTP 4054
Query: 947 YSPAPSSTKSETRVP--------SETARTPFKSPLLKGISAPVISSNPATTEVQ--RKKP 996
+PSST++ T +P SE + T + SP +P + +PATT ++
Sbjct: 4055 SRLSPSSTETTT-LPGSPTTPSLSEKSTTFYTSP-----RSPDATLSPATTTSSGVSEES 4108
Query: 997 SVAFKKPIFTHPMPSPEAVI--------------QTRCPAHAPSSSFTVMALGPPKV--- 1039
S + +P TH P++ Q A S T +LG
Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168
Query: 1040 -SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQL-----N 1093
SP P T+ + + T + S H L SS S + +
Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228
Query: 1094 DSASTPPKPSFLGV------------NESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKG 1141
S +TP PS V + +P++ S+SS++ ++ + H A
Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 4288
Query: 1142 L-KTRLPVGLKVLMKSPQL------------LRKSSTVPGKHEKDS------------LN 1176
L TR VL+ P L S+T G EK + L+
Sbjct: 4289 LFPTRSATS--VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS 4346
Query: 1177 EASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESS 1236
AS +S V++ P SM TA + T+P + + + P T +
Sbjct: 4347 PASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTD-----TTL 4401
Query: 1237 IPGSDGRD--GVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSG-DKPSTPPIEG 1293
PGS G ++ + S S++ L P +T SG + STP
Sbjct: 4402 SPGSTTASSLGPESTTFHSSPGSTETTLLP------------DNTTASGLLEASTPVHSS 4449
Query: 1294 SGKVRTQI--ITNTAERGNSLTRQ----NSSTESSPNKAPSAPMLESLPSVGRPSGHP-- 1345
+G T + +T +G S T Q + T +P SA + S S G PS P
Sbjct: 4450 TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 4509
Query: 1346 --SSGKGSLGSSGSFSSQHGSP---SKLPLRIPPKSEGLL-------IPPGKEDQQAFTQ 1393
S+ +LG S ++ H SP + P + GL+ PG F +
Sbjct: 4510 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 4569
Query: 1394 GECP-----------SANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSST 1442
S+ + S + PT + S T P + TS
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 4629
Query: 1443 SKLETSGRHPDASATATDAVSSEAPLSPTIEE 1474
S+ E++ H AT T + + + S + E
Sbjct: 4630 SE-ESTASHSSQDATGTIVLPARSTTSVLLGE 4660
Score = 48.5 bits (114), Expect = 6e-05
Identities = 122/601 (20%), Positives = 193/601 (32%), Gaps = 56/601 (9%)
Query: 958 TRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQ 1017
T + ++ PF + G+S I+ + AT + + T P A
Sbjct: 178 TSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEES-TVSHSGPGATGT 236
Query: 1018 TRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLE 1077
T P+H+ +S F +G PK SP + T + ++ S P
Sbjct: 237 TLFPSHSATSVF----VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSP-- 290
Query: 1078 MTSSKSVSPGR---KGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGC 1134
+++SP R G S ++ +P P S S S A SH+ P
Sbjct: 291 ---DRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA-SHSIPGST 346
Query: 1135 QSAHEKGLKTRLPVGLK-VLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDS 1193
+ G T +G + S K++ +P L EAS + V + P +
Sbjct: 347 DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAS-TPVHSSTGSPHTT 405
Query: 1194 KNPASMEITAGERNV--TLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRD--GVDNR 1249
+P+S GE + P S+ G S P S +
Sbjct: 406 LSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASST 465
Query: 1250 SMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERG 1309
++ S S+ H P + S H + + GS T T
Sbjct: 466 TLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS--------TQTMHFP 517
Query: 1310 NSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPS--SGKGSL------------GSS 1355
S T S ES+ + S PS H S S GS G S
Sbjct: 518 ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRS 577
Query: 1356 GSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECP------SANVAVLGEPGS 1409
+ H SP + + P + G + G S L E +
Sbjct: 578 EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKST 637
Query: 1410 DRRSCPPTP--TDCPEALQSPGRTQHPSTFE----TSSTSKLETSGRHPDASATATDAVS 1463
S P +P T P ++ S G ++ +T ++ T+ S P S +T + S
Sbjct: 638 TFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS 697
Query: 1464 SEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSR 1523
S P T+ E ++P S E P + AS G ++ +P SS
Sbjct: 698 SPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS--GLLEASMPVHSST 755
Query: 1524 K 1524
+
Sbjct: 756 R 756
Score = 48.5 bits (114), Expect = 6e-05
Identities = 136/650 (20%), Positives = 227/650 (34%), Gaps = 97/650 (14%)
Query: 879 PSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVS 938
PSR + PGS + P++ E T P+A + SP VS
Sbjct: 1414 PSRLSPSSTETTTLPGSPTTPSLS-----EKSTTFYTSPRSPDATL---SPATTTSSGVS 1465
Query: 939 LLARPSYDYSPAPSSTK-SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPS 997
+ S+ + +T ++ S+ ++ P S +G + +S T ++ +
Sbjct: 1466 EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQST 1525
Query: 998 VAFKKPIFTHPMPSPE-----AVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQ 1052
P T P+ +++ P H+ + S P S G+ + S
Sbjct: 1526 TFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT--PASSTSAGLQEESTTF 1583
Query: 1053 TLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPS 1112
D TP +T P+E++++ P + SAS+ + LG +E
Sbjct: 1584 QSWPSSSDT---TPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS----TTLGRSEE-- 1634
Query: 1113 SQVSSSSSSSSPAKSHNSPHGCQSAHEK--GLKTRLPVGLKVLMKSPQLLRKSSTVPGKH 1170
S++ SSP + + +SA G T P+ L S+T G
Sbjct: 1635 ----STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG--STETTALPGSTTTAGLS 1688
Query: 1171 EKDS------------LNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGS 1218
EK + L+ AS +S V++ P S TA + T+P + +
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748
Query: 1219 LADGLPLETALQEPLESSIPGSDGRD--GVDNRSMRRSLSSSKPHLKPALGMNGAKARSH 1276
+ P T + PGS G ++ + S S++ L P
Sbjct: 1749 ASHSSPGSTD-----TTLSPGSTTASSLGPESTTFHSSPGSTETTLLP------------ 1791
Query: 1277 SFSTHSG-DKPSTPPIEGSGKVRTQI--ITNTAERGNSLTRQ----NSSTESSPNKAPSA 1329
+T SG + STP +G T + +T +G S T Q + T +P SA
Sbjct: 1792 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1851
Query: 1330 PMLESLPSVGRPSGHP----SSGKGSLGSSGSFSSQHGSP---SKLPLRIPPKSEGLL-- 1380
+ S S G PS P S+ +LG S ++ H SP + P + GL+
Sbjct: 1852 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1911
Query: 1381 -----IPPGKEDQQAFTQGECP-----------SANVAVLGEPGSDRRSCPPTPTDCPEA 1424
PG F + S+ + P S + PT +
Sbjct: 1912 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1971
Query: 1425 LQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEE 1474
S T P + TS S+ E++ H AT T + + + S + E
Sbjct: 1972 PGSTATTHFPDSSTTSGRSE-ESTASHSSQDATGTIVLPARSTTSVLLGE 2020
Score = 47.4 bits (111), Expect = 1e-04
Identities = 157/735 (21%), Positives = 256/735 (34%), Gaps = 110/735 (14%)
Query: 682 SSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEK 741
+SH + T T + S +ST G E T + +A + AR T E T
Sbjct: 4498 TSHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYH 4556
Query: 742 NIP-KDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNL 800
+ P + P +T S T + TH IS ++ S+ L
Sbjct: 4557 SSPGSTQTMHFPESNTTSGRGEESTTSHSST-----THTISSAPSTTSA----------L 4601
Query: 801 TKIPPRGKSSPQKSKLME-PEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFEL 859
+ P SSP + P+++T S T S A G + ++ +S L E
Sbjct: 4602 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 4661
Query: 860 RSDPHIP--KHSAQLPHSSRMPSRRDWVQCPKSQTPGSR--SRPAIESSDSGEPPTRDEH 915
+ P + LP S+ P + KS T S S P S S R E
Sbjct: 4662 TTSPISSGSMETTALPGSTTTPGLSE-----KSTTFHSSPSSTPTTHFSASSTTLGRSEE 4716
Query: 916 CGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETAR-TPFKSPLL 974
+ + V + + P P + S L S Y +P ST++ S TA +S
Sbjct: 4717 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS 4776
Query: 975 KGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMAL 1034
+ ISS P+TT ++P T SP ++ T P + +S + +
Sbjct: 4777 HSSTTHTISSPPSTTSALVEEP---------TSYHSSPGSIATTHFPESSTTSGRSEEST 4827
Query: 1035 GPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLND 1094
G+ T T R T ISP + E +++ + K +
Sbjct: 4828 ASHSSPDTNGITPLPAHFT--TSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILY 4885
Query: 1095 SASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLM 1154
S+S P + SP+S SSS S P S E T P
Sbjct: 4886 SSSRSPDQTL-----SPASMTSSSIS--------GEPTSLYSQAESTHTTAFPA------ 4926
Query: 1155 KSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQ 1214
S+T G ++ + + S E + +P S+ ++ + T P SQ
Sbjct: 4927 --------STTTSGLSQESTTFHSKPGST-------ETTLSPGSITTSSFAQEFTTPHSQ 4971
Query: 1215 AQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKAR 1274
+L+ P T ++PG LS + G A
Sbjct: 4972 PGSALSTVSPAST--------TVPG---------------LSEESTTFYSSPGSTETTAF 5008
Query: 1275 SHSFSTHSGDKPSTPPIEGSGKVRTQI--ITNTAERGNSLTRQNSSTESS-----PNKAP 1327
SHS + + STP + G T + T + G T +SS++++ P ++
Sbjct: 5009 SHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARST 5068
Query: 1328 SAPMLES------LPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLI 1381
++ ++ PS + P+S S G + ++ H SPS + +S L
Sbjct: 5069 ASDLVGEPTTFYISPSPTYTTLFPASSSTS-GLTEESTTFHTSPSFTSTIVSTESLETLA 5127
Query: 1382 PPGKEDQQAFTQGEC 1396
P ++ Q + +C
Sbjct: 5128 PGLCQEGQIWNGKQC 5142
Score = 46.6 bits (109), Expect = 2e-04
Identities = 127/595 (21%), Positives = 206/595 (34%), Gaps = 69/595 (11%)
Query: 892 TPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAP 951
+P + P+ ++ GEP T ++ S P P + S + S Y +P
Sbjct: 401 SPHTTLSPSSSTTHEGEPTTF--------QSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 452
Query: 952 SST-------KSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPI 1004
SST S T SE + SP+ + P S T ++ + + P
Sbjct: 453 SSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARS---ATSGHVEESTAYHRSPG 509
Query: 1005 FTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQ 1064
T M PE+ + + + + S + TS +LG+ +
Sbjct: 510 STQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTE------ 563
Query: 1065 TPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSP 1124
+TH S ++S GR + S S+P + + + V S+ SP
Sbjct: 564 ------TTH----FRDSSTIS-GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSP 612
Query: 1125 AKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNE--ASKSS 1182
S + T LP P L KS+T AS +S
Sbjct: 613 ISSGSME-----------TTALPGS----TTKPGLSEKSTTFYSSPRSPDTTHLPASMTS 657
Query: 1183 VAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDG 1242
V++ P S TA + T+P + + + P T S+ S G
Sbjct: 658 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG 717
Query: 1243 RDGVDNRSMRRSLSSS-KPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQI 1301
+ S S ++ P A G+ A HS ST S +P GS + +
Sbjct: 718 PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS-STRSPHTTLSP--AGSTTRQGES 774
Query: 1302 ITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQ 1361
T + + TR T +S PS S S+ P+ H S+ + G ++
Sbjct: 775 TTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI--PTTHISARSTTSGLVEESTTY 832
Query: 1362 HGSPSKLPLRIPPKSEGLLIPPGKE-----DQQAFTQGECPSANVAVLGEPGSDRRSCPP 1416
H SP P+S+ G+E T PS A++ EP S S
Sbjct: 833 HSSPGSTQTMHFPESD-TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 891
Query: 1417 T-PTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
T T P++ + GR++ T+S S + +G + + T + E+ SP
Sbjct: 892 TATTHFPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSP 942
Score = 44.3 bits (103), Expect = 0.001
Identities = 134/646 (20%), Positives = 221/646 (34%), Gaps = 89/646 (13%)
Query: 879 PSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVS 938
PSR + PGS + P++ E T P+A + SP VS
Sbjct: 2971 PSRLSPSSTETTTLPGSPTTPSLS-----EKSTTFYTSPRSPDATL---SPATTTSSGVS 3022
Query: 939 LLARPSYDYSPAPSSTK-SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPS 997
+ S+ + +T ++ S ++ P S +G + +S T ++ +
Sbjct: 3023 EESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQST 3082
Query: 998 VAFKKPIFTHPMPSPE-----AVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQ 1052
P T P+ +++ P H+ + S P S G+ + S
Sbjct: 3083 TFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT--PASSTSAGLQEESTTF 3140
Query: 1053 TLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPS 1112
D TP +T P+E++++ P + SAS+ + LG +E
Sbjct: 3141 QSWPSSSDT---TPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS----TTLGRSEE-- 3191
Query: 1113 SQVSSSSSSSSPAKSHNSPHGCQSAHEK--GLKTRLPVGLKVLMKSPQLLRKSSTVPGKH 1170
S++ SSP + + +SA G T P+ L S+T G
Sbjct: 3192 ----STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG--STETTALPGSTTTAGLS 3245
Query: 1171 EKDS------------LNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGS 1218
EK + L+ AS +S V++ P S TA + T+P + +
Sbjct: 3246 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 3305
Query: 1219 LADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSS-KPHLKPALGMNGAKARSHS 1277
+ P T S+ S G + S S ++ P A G+ A HS
Sbjct: 3306 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 3365
Query: 1278 FSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQ----NSSTESSPNKAPSAPMLE 1333
+G +T GS T +G S T Q + T +P SA +
Sbjct: 3366 ---STGSPHTTLSPAGS----------TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412
Query: 1334 SLPSVGRPSGHP----SSGKGSLGSSGSFSSQHGSP---SKLPLRIPPKSEGLL------ 1380
S S G PS P S+ +LG S ++ H SP + P + GL+
Sbjct: 3413 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTY 3472
Query: 1381 -IPPGKEDQQAFTQGECP-----------SANVAVLGEPGSDRRSCPPTPTDCPEALQSP 1428
PG F + + S+ + S + PT + S
Sbjct: 3473 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 3532
Query: 1429 GRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEE 1474
T P + TS S+ E++ H AT T + + + S + E
Sbjct: 3533 ATTHFPDSSTTSGRSE-ESTASHSSQDATGTIVLPARSTTSVLLGE 3577
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 673
Score = 63.9 bits (154), Expect = 1e-09
Identities = 146/640 (22%), Positives = 234/640 (36%), Gaps = 109/640 (17%)
Query: 760 SSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRG------------ 807
S+ ++T++P + L S ++A + + + +LT+ PPR
Sbjct: 117 STASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLT 176
Query: 808 KSSPQKSKLMEPEAT--TLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHI 865
++ P+ S P T T +PS+ +T S A LSR T + R+ P
Sbjct: 177 RTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPP-----RASPTG 231
Query: 866 PKHSAQLPHSSRMPSRRDWVQCPKSQTP-GSRSRPAIESSDSGEPPTRDEHCGSGPEAGV 924
A L S MPS ++ P +P G SR ++ DS TR
Sbjct: 232 SPPRASL---SMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTP---------- 278
Query: 925 KSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISS 984
PS P G +R S +P ST S R+ + T +S ++
Sbjct: 279 SRPSTASPTGTP----SRASLSMTP---STASLMRMLPRASPTGM-------LSRTSLTK 324
Query: 985 NPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRG 1044
+T + R P + + T SP T P PS + G P + G
Sbjct: 325 MDSTASISRTPPRASITR---TPSRASPTGKPSTASPTGTPSRA---SPTGSPSTASLTG 378
Query: 1045 VPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSAS---TPPK 1101
+ T+ GTP R TP + T +P + + +S +++ +AS TPP+
Sbjct: 379 LSSTA--SPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPR 436
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLR 1161
S G S + S +S + +S SP G S T P G SP
Sbjct: 437 ASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPS-------TASPTG------SP---- 479
Query: 1162 KSSTVPGKHEKDSLNEA-SKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLA 1220
+++ G + SL S++S+ +S ++ P+ T + P +LA
Sbjct: 480 STASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPT-WTPSTASPTGSPSTALA 538
Query: 1221 DGLPLETAL-QEPLESSIPGSDGRDGVDNRSMRRSLSSSK-----PHLKPALGMNGAKAR 1274
G P AL + P +S+ + R + S R SL+ + + P+ G +R
Sbjct: 539 MGSPSRAALTRTPSRASLTRTPSRASLTTPS-RASLTRTPSTVLLTRMPPSASPTGMPSR 597
Query: 1275 SHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLES 1334
T PS+ + T IT T R S TE+ P +P+
Sbjct: 598 -----TSPTGMPSSALLTKMDS--TASITRTPPRA-------SPTETPPRASPT-----G 638
Query: 1335 LPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPP 1374
P P+G P +S + + SP+ P R P
Sbjct: 639 TPPRASPTGTPPR------ASPTGTPPRASPTGTPSRASP 672
Score = 33.1 bits (74), Expect = 2.7
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 11/197 (5%)
Query: 1319 TESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEG 1378
+ +SP + PS L PS +G PS+ SL + S +S G+P + L+
Sbjct: 9 SRASPTRTPSTASLTGTPSRASLTGTPST--ASLMGTPSRASLTGTPPRASLKGTTSMAS 66
Query: 1379 LLIPPGKED----QQAFTQGECPS-ANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQH 1433
L++ P + Q + PS A++ + S R+ P + T+
Sbjct: 67 LMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLP--RASLMRRPSTASLTRS 124
Query: 1434 PSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKP 1493
PS ++T + P +A T + +P M ++ + + P
Sbjct: 125 PSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASP 184
Query: 1494 TSVEAKQKPG--PSFAS 1508
T + ++ P PS AS
Sbjct: 185 TGMPSRTSPTGMPSTAS 201
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.2 bits (152), Expect = 2e-09
Identities = 177/902 (19%), Positives = 295/902 (32%), Gaps = 162/902 (17%)
Query: 735 SEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNS---RSSAP 791
SE E+ K V V E + + P QQ+ KP + P
Sbjct: 182 SEASQEETTKKQKV-----VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 792 MGIYQKQ-NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKT 850
I +Q K P G P + P+ + L++ + K + ++
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQT-----DHAKLPLQRDASRPQTKQADIVRG 291
Query: 851 ESSGPLFELRSDPHI------------PKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSR 898
ES P S P I P H P ++ P++ + P +Q PG+ +
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-VK 350
Query: 899 PAIESSDSGEPPTRDEHCGSGP--EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKS 956
P ++ + +PP + P + G + PS P ++ LA+P P+
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPP-GVGKTPAQQPG 406
Query: 957 ETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQR----------------------- 993
+ P++ TP G+ +P + P T VQ+
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 994 KKPSVAFKKPIFTHPM------PSPEAVIQTRCPAHAPSSSF-TVMALGPPKVSPKRGVP 1046
KP P P P P+ + P+ P S+ GP K SP++
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526
Query: 1047 KTSPRQTLGT--------------------PQRDIG----LQTPRISPSTHEPLEMTSSK 1082
P Q G+ P G LQ P +SPS +P K
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1083 SVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGL 1142
++ P P K +F E ++ S + +P + C + +
Sbjct: 587 TICP-LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQ---M 642
Query: 1143 KTRLPVGLKVLMKSPQ------------LLRKSSTVPGK--HEKDSLNEASKSSVAVNKS 1188
K L L + SPQ + KSS P + +KD+ + S K
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702
Query: 1189 KPEDSKNPA----------------SMEITAGERNVTLPDSQAQGSLADGLPLETALQEP 1232
P K P S+ A + ++P Q + +AD P + + +P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 1233 LESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPST---- 1288
+ S D S + S ++ P L + AK S SF +G+K S
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQ-SQAEEKTTPPLKTDSAKP-SQSFPP-TGEKVSPFDSK 819
Query: 1289 ----------------PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSP----NKAPS 1328
P E G+ + + E + T+ + ++ P + P
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 1329 APMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQ 1388
P + +V P P + S S + S +P P G L G
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFG---A 936
Query: 1389 QAFTQGECPSANVAVLGEPGSDRRSCPPTP-TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
F+Q S ++ G+PG +S P P P Q P P + + + ++
Sbjct: 937 SIFSQA---SNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
Query: 1448 SGRHPDASATATDAVSSEAPLSPTIE----EKVMLCIQEN---VEKGQVQTKPTSVEAKQ 1500
+ A A + + +A +PT++ EK I+++ + Q PT +E
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Query: 1501 KP 1502
KP
Sbjct: 1054 KP 1055
Score = 58.5 bits (140), Expect = 6e-08
Identities = 162/775 (20%), Positives = 260/775 (33%), Gaps = 162/775 (20%)
Query: 917 GSGPEAGVKSPSP-----------------PPPPGRSVSLLARPSYDYSPAPSSTKSETR 959
GS P A +SPS PP PGR A+P S + +SE +
Sbjct: 69 GSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP----AQPGLSKSRTTDTFRSEQK 124
Query: 960 VPSETART--------------PFKSPLLKGISAPVISSNPATTEVQRKKP--------- 996
+P + T KS ++ G + V + + ++ V + P
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 997 ---SVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQT 1053
K+ + PE +I+ PPK PK+ P P Q
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQ------------PPKPIPKQQGPGRDPLQQ 232
Query: 1054 LGTPQRDIGLQTPRIS---PSTHEPLEMTSSKSVSPGRKGQLNDSASTP-PKPSFLGVNE 1109
GTP+ Q +I P T +P++ + + K L AS P K + + E
Sbjct: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
Query: 1110 SPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK-----GLKTRLPVGL-KVLMKSPQLLRKS 1163
S + S S + P Q HEK P GL K L + P ++
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 1164 STVPG--KHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLAD 1221
PG K L A + KP S+ P G + + P
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQP-------GPKALAQPPGVG------ 398
Query: 1222 GLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTH 1281
+T Q+P + P + + + KP + + AKA
Sbjct: 399 ----KTPAQQPGPAKPP-------------TQQVGTPKPLAQQPGLQSPAKAPG------ 435
Query: 1282 SGDKPSTPPIE--GSGKVRTQIITNTAERGNSLTRQNSSTE-SSPNKAPSAPMLESLPSV 1338
P+ P++ G GK+ Q A G + +Q T+ S P+ P +
Sbjct: 436 ----PTKTPVQQPGPGKIPAQ----QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487
Query: 1339 GRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPS 1398
P P S K GS P P + P+ G PP ++ A + PS
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 1399 -------ANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRH 1451
+ + + GS + PPT + P A Q P + + +T++L
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVS--PSAKQPPSQGLPKTICPLCNTTELLLHVPE 603
Query: 1452 PDASATATDAVSSEAPL-----SPTIEE-KVMLCIQENVEK---GQVQTKPTSVEAKQKP 1502
T T+ ++ L +P + E K LC+ +++ G + P+S + K K
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT 663
Query: 1503 GPSFASWFGFRKSRLPALSS------RKMDISKTKVEKKDAKVLG----FGNRQLKSERK 1552
P + + S P +S K D+SK KK ++ G+ K+++
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 1553 KE---------KKKPELQCETENELIKDTKSAD----NPDGGLQSKNNRRTPQDI 1594
E K+P + E + + D K P L S ++ T DI
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Score = 52.0 bits (123), Expect = 6e-06
Identities = 189/957 (19%), Positives = 332/957 (34%), Gaps = 167/957 (17%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHN-----------------ISCQSNSRSSAPMGI 794
P V +E + P+Q K+VKPT + + Q+ +++ P+
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 795 YQKQNLTKIPPRG-KSSPQKSKLMEPEATTLL------PSSGL--------VTLEKSPAL 839
+ PP G K SP SK + A+ PSS V ++ P
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 840 APGKLSRFMKTESSGPLFELRSDPHIPKHSA----QLPHSSRMP---SRR------DWVQ 886
A K+S + P+ + P P+ +A P S P SRR
Sbjct: 858 AQTKMS---PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 887 CPKSQ--TPGSR-------------SRPAIESSDSGEPPTRDEHCGSGPEAGVK-SPSPP 930
PKSQ TP S+ + S +G+P H SGP A +K +P+P
Sbjct: 915 APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP---GPHSQSGPGAPMKQAPAPS 971
Query: 931 PPPGRSVSLLARPSYDYSPAPS-STKSETRVPSETARTPFKSPLLKGISAPVISSNPATT 989
PP + +PA S K ET+ P+ P K AP + T
Sbjct: 972 QPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP------KAEQAPTVKR----T 1021
Query: 990 EVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTS 1049
E ++K P + K + P +AV+ T+ S + + K
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQ---KAVLPTKLEKSPKPESTCPLCKTELNIGSK-----DP 1073
Query: 1050 PRQTLGTPQRDIGLQTPRISPSTHEP-------LEMTSSKSVSPGRKGQLNDSASTPPKP 1102
P T ++ +P+ H L + +++S GQL D PP P
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS----GQLGDIRKMPPAP 1129
Query: 1103 SFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRK 1162
S + P SSS ++ P + Q + K L + L S + +
Sbjct: 1130 SGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL--SMEKIPP 1187
Query: 1163 SSTVPGKHEKDSLNEASKSSVAVNKSKPEDSK-NPASMEITAGERNVTLPDSQAQGSLAD 1221
T K E+ L + S++ K PE+ K P +I + E+ L + +
Sbjct: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
Query: 1222 GLP-LETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFST 1280
LP +T+ E + + S + + R + + + +P M G + +
Sbjct: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
Query: 1281 HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLT-RQNSSTESSPNKAPSAPMLESLPSVG 1339
DK +T I+ + + E G T +++ +++S ++ P +
Sbjct: 1308 KEDDK-TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS---------- 1356
Query: 1340 RPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPS- 1398
P G +G S G S S ++P IP + +L K+ +F+Q PS
Sbjct: 1357 -PQGLSDTGYSSDGISSSL-------GEIPSLIPTDEKDILKGLKKD---SFSQESSPSS 1405
Query: 1399 ----------------ANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSST 1442
A + L + S++++ P + PE + +TQ S +
Sbjct: 1406 PSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS--PEQPKDQEKTQSLSETLEITI 1463
Query: 1443 SKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKP 1502
S+ E + T + P S +EK + + S E++ P
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 1503 GPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQL------------KSE 1550
P ++ R ++ S D K + + + F +Q+ + +
Sbjct: 1524 VP--------QRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDD 1575
Query: 1551 RKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHS 1607
+ E+ TE++ ++TK G + + +RR + + + RHS
Sbjct: 1576 EFIRNQLKEISSSTESQKKEETKG----KGKITAGKHRRLTRKSSTSIDEDAGRRHS 1628
Score = 51.2 bits (121), Expect = 9e-06
Identities = 189/958 (19%), Positives = 318/958 (33%), Gaps = 143/958 (14%)
Query: 926 SPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV--------PSETARTPFKSPLLKGI 977
S S P P S A P D S AP K V PS A+ P P +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP---PEADSL 729
Query: 978 SAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPP 1037
S P P+ Q K P K P+ + V + S V +
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 1038 KVSPKRGVPKTSPRQTLG------TPQRDIGLQTP----RISPSTHEPLEMTSSKSVSPG 1087
K +P P Q+ +P + P +I E K V P
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 1088 RKGQLNDSAST--PPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTR 1145
+K + A T PKP + P + S + P P QS + R
Sbjct: 850 QKKEEPKKAQTKMSPKP-----DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904
Query: 1146 LPVGLKVLMKSP--QLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITA 1203
+ L + +P Q TV GK + S++S ++ TA
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS---------------TA 949
Query: 1204 GERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDG---RDGVDNRSMRRSLSSSKP 1260
G+ P SQ+ G P++ Q P S P S G G + +S+ K
Sbjct: 950 GQPG---PHSQS----GPGAPMK---QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Query: 1261 HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE 1320
PA KA + + PPI+ S + TAE ++ + E
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL-------TAEPQKAVL--PTKLE 1050
Query: 1321 SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHG-SPSKLPLRIPPKSEGL 1379
SP + P+ ++ ++G S P + + G +P+
Sbjct: 1051 KSPKPESTCPLCKTELNIG--SKDPPNFNTCTECKNQVCNLCGFNPT------------- 1095
Query: 1380 LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFET 1439
P + Q + C + A+ G+ G D R PP P+ P+A P T+ S+ +T
Sbjct: 1096 ---PHLTEIQEWLCLNCQTQR-AISGQLG-DIRKMPPAPSG-PKASPMPVPTE-SSSQKT 1148
Query: 1440 SSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKV--MLCIQENVEKGQVQTKPTSVE 1497
+ +++ + T + V E EK+ M+ + E+ +++ S
Sbjct: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL 1208
Query: 1498 AKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKK-----DAKVLGFGNRQLKSERK 1552
++KP P K +P + + K +E+K D K+L E+K
Sbjct: 1209 QEKKPLPE-------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK 1261
Query: 1553 KEKKKPELQCETEN-------ELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNR 1605
+ K ++Q E + +++ K GL S + P++ K
Sbjct: 1262 HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 1606 HSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGN 1665
P C+ K + + +K+ S S L + S I SS+
Sbjct: 1322 QPP--CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLG---- 1375
Query: 1666 HKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTF 1725
+ +P D K+ + L++D + S + + + ++ +
Sbjct: 1376 -------EIPSLIPTDE--KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 1726 PLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSS---MRAQTLEREVPSSTDGQRP 1782
+ + T + P+ P+D E L L S ++ ER+ D Q+
Sbjct: 1427 LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Query: 1783 ADSAIVHSTS----DPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFG 1836
S+ H D I T R +P S + SS+ +N P+ + +S G
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRR----------EPYDSVEESSESENSPVPQRKRRTSVG 1534
Score = 32.7 bits (73), Expect = 3.5
Identities = 67/258 (25%), Positives = 92/258 (35%), Gaps = 37/258 (14%)
Query: 888 PKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDY 947
P SQ P P++ S + P S + + P PPPPP P
Sbjct: 2372 PASQLPSGS--PSVSSLPAKPRPF---FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 948 SPAPSSTKSETRVPSE--------TARTPFKSPLLKGISAPVISSN--PATTEVQRKKPS 997
P P+S K T +P + T TP + + V+ SN P T P
Sbjct: 2427 LPPPTSPK-PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485
Query: 998 VAFKKP------IFTH-PMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPK-RGVPKTS 1049
V K +FTH P PS + P+++ P + PK G+ TS
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT-----QKPTDIHPKPTGLSLTS 2540
Query: 1050 PRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGV-N 1108
D L PS PL S+KS SP L ++ PS G
Sbjct: 2541 SMTLNLVTSADYKL------PSPTSPLSPHSNKS-SPRFSKSLTETYVVITLPSEPGTPT 2593
Query: 1109 ESPSSQVSSSSSSSSPAK 1126
+S +SQ +S SP+K
Sbjct: 2594 DSSASQAITSWPLGSPSK 2611
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.2 bits (152), Expect = 2e-09
Identities = 177/902 (19%), Positives = 295/902 (32%), Gaps = 162/902 (17%)
Query: 735 SEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNS---RSSAP 791
SE E+ K V V E + + P QQ+ KP + P
Sbjct: 182 SEASQEETTKKQKV-----VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 792 MGIYQKQ-NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKT 850
I +Q K P G P + P+ + L++ + K + ++
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQT-----DHAKLPLQRDASRPQTKQADIVRG 291
Query: 851 ESSGPLFELRSDPHI------------PKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSR 898
ES P S P I P H P ++ P++ + P +Q PG+ +
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-VK 350
Query: 899 PAIESSDSGEPPTRDEHCGSGP--EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKS 956
P ++ + +PP + P + G + PS P ++ LA+P P+
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPP-GVGKTPAQQPG 406
Query: 957 ETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQR----------------------- 993
+ P++ TP G+ +P + P T VQ+
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 994 KKPSVAFKKPIFTHPM------PSPEAVIQTRCPAHAPSSSF-TVMALGPPKVSPKRGVP 1046
KP P P P P+ + P+ P S+ GP K SP++
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526
Query: 1047 KTSPRQTLGT--------------------PQRDIG----LQTPRISPSTHEPLEMTSSK 1082
P Q G+ P G LQ P +SPS +P K
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1083 SVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGL 1142
++ P P K +F E ++ S + +P + C + +
Sbjct: 587 TICP-LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQ---M 642
Query: 1143 KTRLPVGLKVLMKSPQ------------LLRKSSTVPGK--HEKDSLNEASKSSVAVNKS 1188
K L L + SPQ + KSS P + +KD+ + S K
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702
Query: 1189 KPEDSKNPA----------------SMEITAGERNVTLPDSQAQGSLADGLPLETALQEP 1232
P K P S+ A + ++P Q + +AD P + + +P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 1233 LESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPST---- 1288
+ S D S + S ++ P L + AK S SF +G+K S
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQ-SQAEEKTTPPLKTDSAKP-SQSFPP-TGEKVSPFDSK 819
Query: 1289 ----------------PPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSP----NKAPS 1328
P E G+ + + E + T+ + ++ P + P
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 1329 APMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQ 1388
P + +V P P + S S + S +P P G L G
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFG---A 936
Query: 1389 QAFTQGECPSANVAVLGEPGSDRRSCPPTP-TDCPEALQSPGRTQHPSTFETSSTSKLET 1447
F+Q S ++ G+PG +S P P P Q P P + + + ++
Sbjct: 937 SIFSQA---SNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
Query: 1448 SGRHPDASATATDAVSSEAPLSPTIE----EKVMLCIQEN---VEKGQVQTKPTSVEAKQ 1500
+ A A + + +A +PT++ EK I+++ + Q PT +E
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Query: 1501 KP 1502
KP
Sbjct: 1054 KP 1055
Score = 58.5 bits (140), Expect = 6e-08
Identities = 162/775 (20%), Positives = 260/775 (33%), Gaps = 162/775 (20%)
Query: 917 GSGPEAGVKSPSP-----------------PPPPGRSVSLLARPSYDYSPAPSSTKSETR 959
GS P A +SPS PP PGR A+P S + +SE +
Sbjct: 69 GSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP----AQPGLSKSRTTDTFRSEQK 124
Query: 960 VPSETART--------------PFKSPLLKGISAPVISSNPATTEVQRKKP--------- 996
+P + T KS ++ G + V + + ++ V + P
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 997 ---SVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQT 1053
K+ + PE +I+ PPK PK+ P P Q
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQ------------PPKPIPKQQGPGRDPLQQ 232
Query: 1054 LGTPQRDIGLQTPRIS---PSTHEPLEMTSSKSVSPGRKGQLNDSASTP-PKPSFLGVNE 1109
GTP+ Q +I P T +P++ + + K L AS P K + + E
Sbjct: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
Query: 1110 SPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK-----GLKTRLPVGL-KVLMKSPQLLRKS 1163
S + S S + P Q HEK P GL K L + P ++
Sbjct: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 1164 STVPG--KHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLAD 1221
PG K L A + KP S+ P G + + P
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQP-------GPKALAQPPGVG------ 398
Query: 1222 GLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTH 1281
+T Q+P + P + + + KP + + AKA
Sbjct: 399 ----KTPAQQPGPAKPP-------------TQQVGTPKPLAQQPGLQSPAKAPG------ 435
Query: 1282 SGDKPSTPPIE--GSGKVRTQIITNTAERGNSLTRQNSSTE-SSPNKAPSAPMLESLPSV 1338
P+ P++ G GK+ Q A G + +Q T+ S P+ P +
Sbjct: 436 ----PTKTPVQQPGPGKIPAQ----QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487
Query: 1339 GRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPS 1398
P P S K GS P P + P+ G PP ++ A + PS
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 1399 -------ANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRH 1451
+ + + GS + PPT + P A Q P + + +T++L
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVS--PSAKQPPSQGLPKTICPLCNTTELLLHVPE 603
Query: 1452 PDASATATDAVSSEAPL-----SPTIEE-KVMLCIQENVEK---GQVQTKPTSVEAKQKP 1502
T T+ ++ L +P + E K LC+ +++ G + P+S + K K
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT 663
Query: 1503 GPSFASWFGFRKSRLPALSS------RKMDISKTKVEKKDAKVLG----FGNRQLKSERK 1552
P + + S P +S K D+SK KK ++ G+ K+++
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 1553 KE---------KKKPELQCETENELIKDTKSAD----NPDGGLQSKNNRRTPQDI 1594
E K+P + E + + D K P L S ++ T DI
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Score = 52.0 bits (123), Expect = 6e-06
Identities = 189/957 (19%), Positives = 332/957 (34%), Gaps = 167/957 (17%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLVKPTHN-----------------ISCQSNSRSSAPMGI 794
P V +E + P+Q K+VKPT + + Q+ +++ P+
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 795 YQKQNLTKIPPRG-KSSPQKSKLMEPEATTLL------PSSGL--------VTLEKSPAL 839
+ PP G K SP SK + A+ PSS V ++ P
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 840 APGKLSRFMKTESSGPLFELRSDPHIPKHSA----QLPHSSRMP---SRR------DWVQ 886
A K+S + P+ + P P+ +A P S P SRR
Sbjct: 858 AQTKMS---PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 887 CPKSQ--TPGSR-------------SRPAIESSDSGEPPTRDEHCGSGPEAGVK-SPSPP 930
PKSQ TP S+ + S +G+P H SGP A +K +P+P
Sbjct: 915 APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP---GPHSQSGPGAPMKQAPAPS 971
Query: 931 PPPGRSVSLLARPSYDYSPAPS-STKSETRVPSETARTPFKSPLLKGISAPVISSNPATT 989
PP + +PA S K ET+ P+ P K AP + T
Sbjct: 972 QPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP------KAEQAPTVKR----T 1021
Query: 990 EVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTS 1049
E ++K P + K + P +AV+ T+ S + + K
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQ---KAVLPTKLEKSPKPESTCPLCKTELNIGSK-----DP 1073
Query: 1050 PRQTLGTPQRDIGLQTPRISPSTHEP-------LEMTSSKSVSPGRKGQLNDSASTPPKP 1102
P T ++ +P+ H L + +++S GQL D PP P
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS----GQLGDIRKMPPAP 1129
Query: 1103 SFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRK 1162
S + P SSS ++ P + Q + K L + L S + +
Sbjct: 1130 SGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL--SMEKIPP 1187
Query: 1163 SSTVPGKHEKDSLNEASKSSVAVNKSKPEDSK-NPASMEITAGERNVTLPDSQAQGSLAD 1221
T K E+ L + S++ K PE+ K P +I + E+ L + +
Sbjct: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
Query: 1222 GLP-LETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFST 1280
LP +T+ E + + S + + R + + + +P M G + +
Sbjct: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
Query: 1281 HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLT-RQNSSTESSPNKAPSAPMLESLPSVG 1339
DK +T I+ + + E G T +++ +++S ++ P +
Sbjct: 1308 KEDDK-TTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS---------- 1356
Query: 1340 RPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPS- 1398
P G +G S G S S ++P IP + +L K+ +F+Q PS
Sbjct: 1357 -PQGLSDTGYSSDGISSSL-------GEIPSLIPTDEKDILKGLKKD---SFSQESSPSS 1405
Query: 1399 ----------------ANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSST 1442
A + L + S++++ P + PE + +TQ S +
Sbjct: 1406 PSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS--PEQPKDQEKTQSLSETLEITI 1463
Query: 1443 SKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKP 1502
S+ E + T + P S +EK + + S E++ P
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 1503 GPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQL------------KSE 1550
P ++ R ++ S D K + + + F +Q+ + +
Sbjct: 1524 VP--------QRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDD 1575
Query: 1551 RKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHS 1607
+ E+ TE++ ++TK G + + +RR + + + RHS
Sbjct: 1576 EFIRNQLKEISSSTESQKKEETKG----KGKITAGKHRRLTRKSSTSIDEDAGRRHS 1628
Score = 51.2 bits (121), Expect = 9e-06
Identities = 189/958 (19%), Positives = 318/958 (33%), Gaps = 143/958 (14%)
Query: 926 SPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRV--------PSETARTPFKSPLLKGI 977
S S P P S A P D S AP K V PS A+ P P +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP---PEADSL 729
Query: 978 SAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPP 1037
S P P+ Q K P K P+ + V + S V +
Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 1038 KVSPKRGVPKTSPRQTLG------TPQRDIGLQTP----RISPSTHEPLEMTSSKSVSPG 1087
K +P P Q+ +P + P +I E K V P
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 1088 RKGQLNDSAST--PPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTR 1145
+K + A T PKP + P + S + P P QS + R
Sbjct: 850 QKKEEPKKAQTKMSPKP-----DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904
Query: 1146 LPVGLKVLMKSP--QLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITA 1203
+ L + +P Q TV GK + S++S ++ TA
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS---------------TA 949
Query: 1204 GERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDG---RDGVDNRSMRRSLSSSKP 1260
G+ P SQ+ G P++ Q P S P S G G + +S+ K
Sbjct: 950 GQPG---PHSQS----GPGAPMK---QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Query: 1261 HLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTE 1320
PA KA + + PPI+ S + TAE ++ + E
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL-------TAEPQKAVL--PTKLE 1050
Query: 1321 SSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHG-SPSKLPLRIPPKSEGL 1379
SP + P+ ++ ++G S P + + G +P+
Sbjct: 1051 KSPKPESTCPLCKTELNIG--SKDPPNFNTCTECKNQVCNLCGFNPT------------- 1095
Query: 1380 LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFET 1439
P + Q + C + A+ G+ G D R PP P+ P+A P T+ S+ +T
Sbjct: 1096 ---PHLTEIQEWLCLNCQTQR-AISGQLG-DIRKMPPAPSG-PKASPMPVPTE-SSSQKT 1148
Query: 1440 SSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKV--MLCIQENVEKGQVQTKPTSVE 1497
+ +++ + T + V E EK+ M+ + E+ +++ S
Sbjct: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL 1208
Query: 1498 AKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKK-----DAKVLGFGNRQLKSERK 1552
++KP P K +P + + K +E+K D K+L E+K
Sbjct: 1209 QEKKPLPE-------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK 1261
Query: 1553 KEKKKPELQCETEN-------ELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNR 1605
+ K ++Q E + +++ K GL S + P++ K
Sbjct: 1262 HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 1606 HSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGN 1665
P C+ K + + +K+ S S L + S I SS+
Sbjct: 1322 QPP--CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLG---- 1375
Query: 1666 HKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTF 1725
+ +P D K+ + L++D + S + + + ++ +
Sbjct: 1376 -------EIPSLIPTDE--KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 1726 PLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSS---MRAQTLEREVPSSTDGQRP 1782
+ + T + P+ P+D E L L S ++ ER+ D Q+
Sbjct: 1427 LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Query: 1783 ADSAIVHSTS----DPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFG 1836
S+ H D I T R +P S + SS+ +N P+ + +S G
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRR----------EPYDSVEESSESENSPVPQRKRRTSVG 1534
Score = 32.7 bits (73), Expect = 3.5
Identities = 67/258 (25%), Positives = 92/258 (35%), Gaps = 37/258 (14%)
Query: 888 PKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDY 947
P SQ P P++ S + P S + + P PPPPP P
Sbjct: 2372 PASQLPSGS--PSVSSLPAKPRPF---FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 948 SPAPSSTKSETRVPSE--------TARTPFKSPLLKGISAPVISSN--PATTEVQRKKPS 997
P P+S K T +P + T TP + + V+ SN P T P
Sbjct: 2427 LPPPTSPK-PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485
Query: 998 VAFKKP------IFTH-PMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPK-RGVPKTS 1049
V K +FTH P PS + P+++ P + PK G+ TS
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT-----QKPTDIHPKPTGLSLTS 2540
Query: 1050 PRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGV-N 1108
D L PS PL S+KS SP L ++ PS G
Sbjct: 2541 SMTLNLVTSADYKL------PSPTSPLSPHSNKS-SPRFSKSLTETYVVITLPSEPGTPT 2593
Query: 1109 ESPSSQVSSSSSSSSPAK 1126
+S +SQ +S SP+K
Sbjct: 2594 DSSASQAITSWPLGSPSK 2611
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 62.4 bits (150), Expect = 4e-09
Identities = 166/777 (21%), Positives = 278/777 (35%), Gaps = 132/777 (16%)
Query: 721 QPRAAARDYTFFKRSEEDTEKNIP-------KDNVDNVPRVSTESFSSRTVTQNPQQQKL 773
Q + ARD T + S+++ E P K ++ + + +T+ ++++
Sbjct: 861 QKQLLARD-TQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREV 919
Query: 774 VKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTL 833
+P N C + +++ + P G S QK + P T P G L
Sbjct: 920 ERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSP---TPEPGVGAGDL 976
Query: 834 EKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTP 893
P AP ++S G R P P+ + + +MP + + +
Sbjct: 977 P-GPTSAPVPSG----SQSGG-----RGSPVSPRRHQKGLLNCKMPPAE---KASRIRAA 1023
Query: 894 GSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSS 953
SR ES D+ PPT E +P+PP P S S
Sbjct: 1024 EKVSRGDQESPDACLPPTVPE-----------APAPPQKPLNSQS--------------- 1057
Query: 954 TKSETRVPSETARTPFKSPLLKGISAPVISSN----------PATTEVQ--RKKPSVAFK 1001
A P SPLL I V + P ++E++ KP + +
Sbjct: 1058 -------QKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTR 1110
Query: 1002 KPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDI 1061
K P P+ A P PS+S T + P S + + R ++ TP+ +
Sbjct: 1111 KSSRMTPFPATSA-----APEPHPSTS-TAQPVTPKPTS--QATRSRTNRSSVKTPE-PV 1161
Query: 1062 GLQTPRISP--STHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSS 1119
P + P ST +P+ + V+ GRK + + P+ L + S S+ +S
Sbjct: 1162 VPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTS 1221
Query: 1120 SSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSST-VPGKHEKD-SLNE 1177
+S A + +KT P V+ +P+L +ST P E
Sbjct: 1222 EPTSQATRGRK-------NRSSVKTPEP----VVPTAPELQPSTSTDQPVTSEPTYQATR 1270
Query: 1178 ASKSSVAVNKSKPEDSKNPASMEITAGERNVT-LPDSQAQGSLADGLPLETALQEPLESS 1236
K+ +V +P P T+ +R VT P S+ S + ++T E+
Sbjct: 1271 GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTP-----ETV 1325
Query: 1237 IPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDK-----PSTPPI 1291
+P + ++ S S+ +P + P ++R++ S + + P PP
Sbjct: 1326 VPTAP--------ELQISTSTDQP-VTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPS 1376
Query: 1292 EGSGKVRTQIITNTAERGNSLTRQNSSTESSPNK-APSAPMLESLPSVGRPSGHPSSGKG 1350
+ + T T+ A RG R+N S+ +P P+AP LE S +P + +
Sbjct: 1377 TSTEQPVTPEPTSRATRG----RKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQA 1432
Query: 1351 SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSD 1410
+ G + + S K P + P + L P Q T + A G
Sbjct: 1433 TRGRT------NRSSVKTPETVVPTAPEL--QPSTSTDQPVTP---EPTSQATRGRTDRS 1481
Query: 1411 RRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAP 1467
P T LQ+ T P T E +S + T GR +S + V AP
Sbjct: 1482 SVKTPETVVPTAPELQASASTDQPVTSEPTSRT---TRGRKNRSSVKTPETVVPAAP 1535
Score = 58.5 bits (140), Expect = 6e-08
Identities = 181/863 (20%), Positives = 304/863 (35%), Gaps = 168/863 (19%)
Query: 693 RNEISINSTPAGPKAEHTELLPQGIAC--LQPRAAARDYTFFKRSEEDTEKNI------P 744
R E N A P+ + L + +Q + + K E + E+ + P
Sbjct: 871 RQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDP 930
Query: 745 KDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAP-MGIYQKQNLTKI 803
+ + VP+V E + R + Q + Q++S + P +G T
Sbjct: 931 AELEEKVPKVILERDTQRGEPEGGSQDQ--------KGQASSPTPEPGVGAGDLPGPTSA 982
Query: 804 P-PRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSD 862
P P G S + + P GL+ + PA K SR E + D
Sbjct: 983 PVPSGSQSGGRGSPVSPRRH----QKGLLNCKMPPA---EKASRIRAAEKVSRGDQESPD 1035
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEA 922
+P + P + P Q K P P + S TR + PEA
Sbjct: 1036 ACLPPTVPEAPAPPQKPLNS---QSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEA 1092
Query: 923 GVKS------PSPPPPPGRSVSLLARPSYDYSPAPSSTKSETR----------VPSETAR 966
+ S P P +S + P+ +P P + S + S T R
Sbjct: 1093 PLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNR 1152
Query: 967 TPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHP-------------MPSPE 1013
+ K+P PV+ P E+Q PS + +P+ + P + +PE
Sbjct: 1153 SSVKTP------EPVV---PTAPELQ---PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE 1200
Query: 1014 AVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTH 1073
V+ T PS+S P RG R ++ TP+ + P + PST
Sbjct: 1201 TVVPTALELQ-PSTSTDRPVTSEPTSQATRG---RKNRSSVKTPE-PVVPTAPELQPSTS 1255
Query: 1074 EPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHG 1133
+TS + R G+ N S+ P+P V +P + S+S+ K +
Sbjct: 1256 TDQPVTSEPTYQATR-GRKNRSSVKTPEPV---VPTAPELRPSTSTDRPVTPKPTS---- 1307
Query: 1134 CQSAHEKGLKTRLPVGLKVLMKSPQLLRKSST----VPGKHEKDSLNEASKSSVAVNKSK 1189
++ + + + V+ +P+L +ST P + + + + SSV
Sbjct: 1308 -RTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSV------ 1360
Query: 1190 PEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNR 1249
KNP S T+P +A LP T+ ++P+ P S G NR
Sbjct: 1361 ----KNPES----------TVP-------IAPELPPSTSTEQPVTPE-PTSRATRGRKNR 1398
Query: 1250 SMRR---SLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTA 1306
S + +L + P L+P+ S D+P TP T+ A
Sbjct: 1399 SSGKTPETLVPTAPKLEPST---------------STDQPVTPE-----------PTSQA 1432
Query: 1307 ERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPS 1366
RG + SS ++ P+AP L+ S +P + + + G +
Sbjct: 1433 TRGRT---NRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD---------- 1479
Query: 1367 KLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTP-TDCPEA- 1424
R K+ ++P E Q + + + ++ G RS TP T P A
Sbjct: 1480 ----RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAP 1535
Query: 1425 -LQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAP-LSPTIEEKVMLCIQE 1482
LQ T P T E +S + T GR +S +++ AP L P+ ++ +
Sbjct: 1536 ELQPSTSTDQPVTPEPTSRA---TRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEP 1592
Query: 1483 NVEKGQVQTKPTSVEAKQKPGPS 1505
+ +T +SV+ + P+
Sbjct: 1593 TSRATRCRTNRSSVKTPEPVVPT 1615
Score = 55.1 bits (131), Expect = 7e-07
Identities = 146/689 (21%), Positives = 243/689 (35%), Gaps = 118/689 (17%)
Query: 808 KSSPQKSKLMEPEATTLLPSSGL---VTLEKSPALAPGKLSRF-MKTESSGPLFELRSDP 863
+SS + + + P A L PS+ VT E + + G+ SR +KT + L P
Sbjct: 1152 RSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQP 1211
Query: 864 HI----PKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHC--- 916
P S ++R R V+ P+ P + P ++ S S + P E
Sbjct: 1212 STSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP---TAPELQPSTSTDQPVTSEPTYQA 1268
Query: 917 --GSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLL 974
G + VK+P P P + +P P+S + +R + +TP
Sbjct: 1269 TRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTP------ 1322
Query: 975 KGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMAL 1034
V+ P E+Q S + +P+ P P S+ +
Sbjct: 1323 ----ETVV---PTAPELQ---ISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPE 1372
Query: 1035 GPPKVSPKRGV-PKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLN 1093
PP S ++ V P+ + R T G R G +TP T LE ++S
Sbjct: 1373 LPPSTSTEQPVTPEPTSRATRGRKNRSSG-KTPETLVPTAPKLEPSTS-----------T 1420
Query: 1094 DSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVL 1153
D TP P+SQ + ++ S K+ + V+
Sbjct: 1421 DQPVTP----------EPTSQATRGRTNRSSVKTPET---------------------VV 1449
Query: 1154 MKSPQLLRKSST-VPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPD 1212
+P+L +ST P E S +A++ + K ++ P + E+ A
Sbjct: 1450 PTAPELQPSTSTDQPVTPEPTS--QATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1507
Query: 1213 SQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHL-KPALGMNGA 1271
S+ G ++++ P E+ +P + ++ S S+ +P +P
Sbjct: 1508 SEPTSRTTRGRKNRSSVKTP-ETVVPAAP--------ELQPSTSTDQPVTPEPTSRATRG 1558
Query: 1272 KARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNK-APSAP 1330
+ S T P P ++ S R Q++T + R N S+ +P P+AP
Sbjct: 1559 RTNRSSVKTPESIVPIAPELQPSTS-RNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAP 1617
Query: 1331 MLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQA 1390
S +P + + + + S + P + P D +
Sbjct: 1618 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP---------------VEPAASDLEP 1662
Query: 1391 FT---QGECPSANVAVLGEPGSDRRS---CPPTPTDCPEALQSPGRTQHPSTFE---TSS 1441
FT Q P A +A G+ + R S P PT PE QSP T P + E S
Sbjct: 1663 FTPTDQSVTPEA-IAQGGQSKTLRSSTVRAMPVPT-TPE-FQSPVTTDQPISPEPITQPS 1719
Query: 1442 TSKLETSGRHPDASATATDAVSSEAPLSP 1470
K + + +P + A D APL P
Sbjct: 1720 CIKRQRAAGNPGSLAAPIDHKPCSAPLEP 1748
Score = 33.5 bits (75), Expect = 2.0
Identities = 63/318 (19%), Positives = 112/318 (35%), Gaps = 41/318 (12%)
Query: 1290 PIEGSGKVRTQIITNTAERGN----SLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHP 1345
P E KV I+ +RG S ++ ++ +P A L S PSG
Sbjct: 930 PAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQ 989
Query: 1346 SSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLG 1405
S G+GS S + L ++PP + I +A G
Sbjct: 990 SGGRGS-----PVSPRRHQKGLLNCKMPPAEKASRI---------------RAAEKVSRG 1029
Query: 1406 EPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSE 1465
+ S PPT + P Q P +Q P T D S E
Sbjct: 1030 DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDG-SQE 1088
Query: 1466 APLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKM 1525
AP +P E ++ K +++T+ +S + P P+ ++ P+ S+ +
Sbjct: 1089 APEAPLSSE-----LEPFHPKPKIRTRKSS---RMTPFPATSA----APEPHPSTSTAQP 1136
Query: 1526 DISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSK 1585
K + ++ +K+ PELQ T + ++ G +S+
Sbjct: 1137 VTPKPTSQATRSRT---NRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSR 1193
Query: 1586 NNRRTPQDIY-NQLKIEP 1602
++ +TP+ + L+++P
Sbjct: 1194 SSVKTPETVVPTALELQP 1211
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 62.4 bits (150), Expect = 4e-09
Identities = 97/368 (26%), Positives = 131/368 (35%), Gaps = 58/368 (15%)
Query: 789 SAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFM 848
S+P+ I+ Q L+ + +P S +M P LE +LAP L
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPP-------------LETQSSLAPPSLQTPP 527
Query: 849 KTESSGPLFELRS--DPHIPKHSAQL--PHSSRMPSRRDWVQCPKSQTPGSRSRPAIE-- 902
+ ++ PL L S P + SA L PH P CP P + P E
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP---APCPLQAPPSPLTTPPPETP 584
Query: 903 SSDSGEPPTRDEHCGSGPEAGVKSPSPPP---PPGRSVSLLARPSYDYSPAP--SSTKSE 957
SS + PP S P G+ SP P PP ++ LA P P+P S S
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 958 TRVPSETA---------RTPFKSPLLKGISAPVISS-----NPATTEVQRKKPSVAFKKP 1003
PS A + PF P + AP +P+ T + PS+A P
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--AP 702
Query: 1004 IFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGL 1063
P PSP A P +PS++ A PP +P VP + P P
Sbjct: 703 PLQVP-PSPPA-----SPPMSPSATPPPQA-PPPLAAPPLQVPPSPP---ASPPMSPSAT 752
Query: 1064 QTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSS 1123
PR+ P P V P L S P P +P Q S +S
Sbjct: 753 PPPRVPPLLAAP-----PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
Query: 1124 PAKSHNSP 1131
P ++ SP
Sbjct: 808 PGQAPFSP 815
Score = 58.2 bits (139), Expect = 8e-08
Identities = 108/382 (28%), Positives = 141/382 (36%), Gaps = 64/382 (16%)
Query: 800 LTKIPPRGKSS-----PQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLS-----RFMK 849
LT PP SS PQ + LPS L L P AP L+
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 850 TESSGPLFELRS-DPHIPK----HSAQLPHSSRMPSRRDWVQCP----------KSQTPG 894
+S PL L + P P H Q P S P VQ P S TP
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPPVQAPFSPPASPPVSPSATPP 692
Query: 895 SRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSST 954
S++ P++ + PP S P + SPS PPP ++ LA P P+P ++
Sbjct: 693 SQAPPSLAAPPLQVPP-------SPPASPPMSPSATPPP-QAPPPLAAPPLQVPPSPPAS 744
Query: 955 KSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQ-RKKPSVAFKKPIFTHP---MP 1010
+ + R P PLL V S PA+ + KP + T P +P
Sbjct: 745 PPMSPSATPPPRVP---PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 1011 SPEAVIQTRCPAHAPSSSFTV--MALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRI 1068
SP A + P +PS+S + +A PP+ P P Q +P LQ PR
Sbjct: 802 SPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPR- 856
Query: 1069 SPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSS---SSSSSSPA 1125
P T P SVS G + L + PP PS SPSS +S + SSS
Sbjct: 857 RPPTPGP-----DTSVS-GPRLTLALAPGPPPPPS-----RSPSSTLSGPDLAGHSSSAT 905
Query: 1126 KSHNSPHGCQSAHEKGLKTRLP 1147
+ G S E G P
Sbjct: 906 STPEELRGYDSGPEGGAAASPP 927
Score = 57.8 bits (138), Expect = 1e-07
Identities = 152/609 (24%), Positives = 224/609 (36%), Gaps = 114/609 (18%)
Query: 910 PTRDEHCGSGPEAGVKSPSP---PPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETAR 966
P G AG S +P PP GR A P+ + SP P S+ P +
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGER--APPAKNTSPGPVSS------PGRASG 122
Query: 967 TPFKSPL-LKG--ISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAH 1023
T PL KG ISA + TE ++ A + + P P T PA
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG------TPSPAM 176
Query: 1024 APSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKS 1083
A S +G P R P PR P++ + + ST EP
Sbjct: 177 ARRSRAAGTEVGLP-----RPAPSARPRPPTEGPRKSVSSASEH---STTEP-------- 220
Query: 1084 VSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSS--SSPAKSHNSPHGCQSAHEKG 1141
S + +PS G + P+S+ SSS++ SSPA+S S G A
Sbjct: 221 -----------SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 1142 LKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAV-----NKSKPEDSKNP 1196
+ + P GL+ L + PQ+ T P K +L S S +A K++P +
Sbjct: 270 SQPK-PKGLQAL-RPPQV-----TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
Query: 1197 ASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGS----DGRDGVDNRSMR 1252
A+ + A TLP S LA LPL P S P S
Sbjct: 323 AATPLPA-----TLPPSP---PLATPLPL-----APPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 1253 RSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSL 1312
S+++ P+L HS ++ S P +P S + T + + T + +S
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 1313 ----TRQNSSTESSPNK----APSAPMLE---SLPSVG------RPSGHPSSGKGSLGSS 1355
RQ ++ +SP++ P +P L+ SLP+ P+ P S ++
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 1356 GSFSSQHGSPSKLPLR---IPP-KSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDR 1411
+ SS + PL +PP +++ L PP + A + P N+ L P
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA-SLTTPPLENLPSLAPPPLQT 548
Query: 1412 RSC---------PPTPTDCP-EALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDA 1461
S PP P CP +A SP T P T + +T + P A A+
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA----PPALASPPLQ 604
Query: 1462 VSSEAPLSP 1470
PLSP
Sbjct: 605 GLPSPPLSP 613
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 62.4 bits (150), Expect = 4e-09
Identities = 190/875 (21%), Positives = 298/875 (34%), Gaps = 159/875 (18%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLV-------KP------THNISCQSNSRSSAPMGIYQKQ 798
PR S E ++ T+ +++ V KP + S + S SS + K
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 799 NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLV----TLEKSPALAPGKLSRFMKTESSG 854
++ P + K+S +K E A P+ G V K AL P K ++ + ES
Sbjct: 217 SVK--PAQVKASSVSTK--ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 855 PLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDE 914
S+ P + +S + P TPG + PA PP +
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA--------PPGKAG 324
Query: 915 HCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSET-----ARTPF 969
S +AG P S S + S + +PA + + + +T A P
Sbjct: 325 AVASQTKAG-----KPEEDSESSSEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPA 378
Query: 970 KSPLLKGIS-APVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSS 1028
K KG + AP + PA + Q K + S E+ + PA A S
Sbjct: 379 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS-------SEESDSEEEAPAQAKPSG 431
Query: 1029 FTVM---ALGPPKVSPKRGVPKTSPRQT-LGTPQRDIGLQ------TPRISPSTHEPLEM 1078
A P K SP++G PR+T Q +G Q + S S E L
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1079 TSSKSVSPGRKGQLNDSAST-----------PPKPSFLGVNESPSSQV-------SSSSS 1120
++ V P K AST P P +G +PS+QV SSS
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG-PATPSAQVGKWEEDSESSSE 550
Query: 1121 SSSPAKSHNSPHGCQSAHEKGLKTRLPV-GLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SS + P A EK L L K P V K EK N S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 1180 KSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA------QGSLADGLPLETALQEPL 1233
+ + + PA+M + + +P ++A + A P+ Q P
Sbjct: 611 SEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 1234 ES-----------SIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHS 1282
++ ++ G R D+ S S S + K L + +A+S
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE---KTGLAVTVGQAKSVGKGLQV 724
Query: 1283 GDKPSTPPIEGS-------------GKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA 1329
K ++ P++GS G TQ+ E S ++ S E++ + A
Sbjct: 725 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 1330 PMLESLPSVGRP-SGHPSSGKGSLGSSG-----SFSSQHGSPSKL--PLRIPPKSEGLLI 1381
++ + P + S KG++ + G + ++ SPSK+ P+R P S L
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
Query: 1382 PP------------------GKEDQQAFTQGECPS-------ANVAVLGEPGSDRRSCPP 1416
P G E+ ++ E S A V G+ R + P
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 1417 TPTDCPE---ALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIE 1473
+ P A PG+T PS + +S D+ A AV+S + P
Sbjct: 903 A-KESPRKGAAPTPPGKT-GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP-- 958
Query: 1474 EKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFAS 1508
++ + N P +A P + AS
Sbjct: 959 ---LIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
Score = 53.5 bits (127), Expect = 2e-06
Identities = 162/818 (19%), Positives = 281/818 (34%), Gaps = 133/818 (16%)
Query: 876 SRMPSRRDWVQCPKSQTP---GSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPP 932
++ P + P +P G RPA +SS S E + +E G G
Sbjct: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 933 PGRSVSLLARPSYDYSPAP----------SSTKSETRVPSETARTPFKSPLLKGISAPVI 982
++ S+ + S AP + K+E + SE++ S A V
Sbjct: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 983 SS--------NPATTEVQRKKPSVAFKKPIFTHPMPSPE-AVIQTRCPAHAPSSSFTVMA 1033
+S NPA K +++ + T + + + + + P P +S TV+A
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS-TVLA 841
Query: 1034 LGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSK----------S 1083
GP V P G + Q P+ D G + S S E + K +
Sbjct: 842 RGPASV-PSVGKAVATAAQAQTGPEEDSG-SSEEESDSEEEAETLAQVKPSGKTHQIRAA 899
Query: 1084 VSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLK 1143
++P ++ +A TPP G ++Q S S ++ +S +A
Sbjct: 900 LAPAKESPRKGAAPTPP-----GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQV 954
Query: 1144 TRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKN----PASM 1199
+ P+ +SP + P + + S +++S + +S +S++ PA+
Sbjct: 955 IKPPLIFVDPNRSPA---GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 1200 EITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDG----VDNRSMRRSL 1255
+T G R + A +A + A S I ++G VD+
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPA 1071
Query: 1256 SSSKPHLKPALGMNGAKA-------------RSHSFSTHSGDKPSTPPIEGSG----KVR 1298
+S + A G N + S S S D S +G G K
Sbjct: 1072 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1131
Query: 1299 TQIITNTAERGNSLTRQNSSTESSPNK-APSAPMLESLPSVGRPSGHPSSGKGS--LGSS 1355
++ T R +L + ++ S + APS +L + G + + K + L SS
Sbjct: 1132 HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSS 1191
Query: 1356 GSFSS-----------QHGSPSKLPLRIPPKSEGLLIPPGKEDQ------------QAFT 1392
S SS Q P + + PK+ G G Q QA T
Sbjct: 1192 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAST 1251
Query: 1393 QGECPSANVAVLGEPG--SDRRSCPPTPTDCPEALQSPGRTQHPSTFETS----STSKLE 1446
+ +LG+P ++ + E L+ + +T E+S + K +
Sbjct: 1252 LALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRK 1311
Query: 1447 TSGRHPDASATATD-------AVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAK 1499
SG P A + EA +SP EK KG+ + S + K
Sbjct: 1312 LSGDQPAARTPRSKKKKKLGAGEGGEASVSP---EKT-----STTSKGKAKRDKASGDVK 1363
Query: 1500 QKPGPSFASWFGFR-------KSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERK 1552
+K G G + + + + K+K EKK + +RK
Sbjct: 1364 EKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKS-----------DKRK 1412
Query: 1553 KEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRT 1590
K+K+K E + + + KD++S + K +T
Sbjct: 1413 KDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 42.0 bits (97), Expect = 0.006
Identities = 75/365 (20%), Positives = 126/365 (34%), Gaps = 40/365 (10%)
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSS-GLVTLEKSPALAPGKLSRFMKTESSGPLFELRSD 862
P + K+S +K++ A PS+ G ++ A + + ++ P+ ++
Sbjct: 778 PAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS 837
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGE---------PPTRD 913
+ + A +P + + Q + GS E SDS E P +
Sbjct: 838 TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE----EESDSEEEAETLAQVKPSGKT 893
Query: 914 EHCGSGPEAGVKSP---SPPPPPGRSVSLLARPSYDYSPAPSSTKSET--RVPSETARTP 968
+ +SP + P PPG++ A+ SS +S++ P+
Sbjct: 894 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 969 FKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSP-------EAVIQTRCP 1021
P L + + PA T Q + S K S + + T+C
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 1022 AHAPSSSFTVMALGPPKVSPKRGVP-----KTSPRQTLGTPQRDIGLQTPRISPSTHEPL 1076
++ M P+++PK + K S R + G Q Q S L
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVD----SAVGTL 1069
Query: 1077 EMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS---PHG 1133
TS +S S KG + P P ++P S S SS S + S P G
Sbjct: 1070 PATSPQSTSVQAKG--TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
Query: 1134 CQSAH 1138
+SAH
Sbjct: 1128 AKSAH 1132
Score = 37.0 bits (84), Expect = 0.18
Identities = 76/352 (21%), Positives = 121/352 (34%), Gaps = 43/352 (12%)
Query: 1156 SPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA 1215
+P+L +S+V G S+ E +K+ +PA+ + A + P A
Sbjct: 102 TPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSA 161
Query: 1216 QGSLADGLPLETALQEPL----ESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGA 1271
+ S L ET + + ++ PG D+ S S SS + ++ + A
Sbjct: 162 EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPA 221
Query: 1272 KARSHSFSTHSGDKPSTPPIEGS-GKVRTQI---ITNTAERGNSLTRQNSSTESSPNKAP 1327
+ ++ S ST P G G V Q+ A+R ++ S+E
Sbjct: 222 QVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 1328 SAP----------------MLESLPSVGRPSGHPSSGKGSL----GSSGSFSSQ--HGSP 1365
AP S P+ G P GKG+ G +G+ +SQ G P
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTP------GKGATPAPPGKAGAVASQTKAGKP 335
Query: 1366 SKLPLRIPPKSEGL--LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTP---TD 1420
+ +S P K QA G+ A S R+ P P T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 1421 CPEALQSPGRTQH--PSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
A G+ + S+ E S + + + P A A S+ A SP
Sbjct: 396 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.4 bits (150), Expect = 4e-09
Identities = 190/875 (21%), Positives = 298/875 (34%), Gaps = 159/875 (18%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLV-------KP------THNISCQSNSRSSAPMGIYQKQ 798
PR S E ++ T+ +++ V KP + S + S SS + K
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 799 NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLV----TLEKSPALAPGKLSRFMKTESSG 854
++ P + K+S +K E A P+ G V K AL P K ++ + ES
Sbjct: 217 SVK--PAQVKASSVSTK--ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 855 PLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDE 914
S+ P + +S + P TPG + PA PP +
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA--------PPGKAG 324
Query: 915 HCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSET-----ARTPF 969
S +AG P S S + S + +PA + + + +T A P
Sbjct: 325 AVASQTKAG-----KPEEDSESSSEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPA 378
Query: 970 KSPLLKGIS-APVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSS 1028
K KG + AP + PA + Q K + S E+ + PA A S
Sbjct: 379 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS-------SEESDSEEEAPAQAKPSG 431
Query: 1029 FTVM---ALGPPKVSPKRGVPKTSPRQT-LGTPQRDIGLQ------TPRISPSTHEPLEM 1078
A P K SP++G PR+T Q +G Q + S S E L
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1079 TSSKSVSPGRKGQLNDSAST-----------PPKPSFLGVNESPSSQV-------SSSSS 1120
++ V P K AST P P +G +PS+QV SSS
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG-PATPSAQVGKWEEDSESSSE 550
Query: 1121 SSSPAKSHNSPHGCQSAHEKGLKTRLPV-GLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SS + P A EK L L K P V K EK N S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 1180 KSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA------QGSLADGLPLETALQEPL 1233
+ + + PA+M + + +P ++A + A P+ Q P
Sbjct: 611 SEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 1234 ES-----------SIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHS 1282
++ ++ G R D+ S S S + K L + +A+S
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE---KTGLAVTVGQAKSVGKGLQV 724
Query: 1283 GDKPSTPPIEGS-------------GKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA 1329
K ++ P++GS G TQ+ E S ++ S E++ + A
Sbjct: 725 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 1330 PMLESLPSVGRP-SGHPSSGKGSLGSSG-----SFSSQHGSPSKL--PLRIPPKSEGLLI 1381
++ + P + S KG++ + G + ++ SPSK+ P+R P S L
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
Query: 1382 PP------------------GKEDQQAFTQGECPS-------ANVAVLGEPGSDRRSCPP 1416
P G E+ ++ E S A V G+ R + P
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 1417 TPTDCPE---ALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIE 1473
+ P A PG+T PS + +S D+ A AV+S + P
Sbjct: 903 A-KESPRKGAAPTPPGKT-GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP-- 958
Query: 1474 EKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFAS 1508
++ + N P +A P + AS
Sbjct: 959 ---LIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
Score = 50.1 bits (118), Expect = 2e-05
Identities = 177/863 (20%), Positives = 288/863 (33%), Gaps = 186/863 (21%)
Query: 876 SRMPSRRDWVQCPKSQTP---GSRSRPAIESSDSGEPPTRDEHCGSGPEAG--------- 923
++ P + P +P G RPA +SS S E + +E G G
Sbjct: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 924 -VKSPSPPPP-----------PGRSVSLLAR----------PSYDYSPAPSSTKSETRVP 961
VK+ S P PG++ + + S + S + + S +V
Sbjct: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 962 SETARTPFKS-------PLLKG-ISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPE 1013
+ +T K+ P KG ISAP T Q K+ S + KP +P S
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAP---GKVVTAAAQAKQRSPSKVKPPVRNPQNS-- 837
Query: 1014 AVIQTRCPAHAPSSSFTVM----------------------------------------- 1032
+ R PA PS V
Sbjct: 838 -TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
Query: 1033 --ALGPPKVSPKRGVP-----KTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVS 1085
AL P K SP++G KT P Q D G + P +TS++ +
Sbjct: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 956
Query: 1086 P-----GRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEK 1140
P A+TP + + S++ SSSS ++ + Q
Sbjct: 957 PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL-TP 1015
Query: 1141 GLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASME 1200
G++T + + + P++ K+S K+S + S + KNPAS+
Sbjct: 1016 GIRTNV---VTMPTAHPRIAPKASMAGASSSKES-SRISDGKKQEGPATQVSKKNPASLP 1071
Query: 1201 ITAGERNVTLPD-SQAQGSLADGLP---LETALQEPLESSIPGSDGRDGVDNRSMRRSLS 1256
+T V S+AQ +A P +++A+ L ++ P S +R
Sbjct: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGT-LPATSPQSTSVQAKGTNKLR---- 1126
Query: 1257 SSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQ---IITNTAERGNSLT 1313
KP L P + S S S D S +G G + + T R +L
Sbjct: 1127 --KPKL-PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV 1183
Query: 1314 RQNSSTESSPNK-APSAPMLESLPSVGRPSGHPSSGKGS--LGSSGSFSS---------- 1360
+ ++ S + APS +L + G + + K + L SS S SS
Sbjct: 1184 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
Query: 1361 -QHGSPSKLPLRIPPKSEGLLIPPGKEDQ------------QAFTQGECPSANVAVLGEP 1407
Q P + + PK+ G G Q QA T + +LG+P
Sbjct: 1244 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
Query: 1408 G--SDRRSCPPTPTDCPEALQSPGRTQHPSTFETS----STSKLETSGRHPDASATATD- 1460
++ + E L+ + +T E+S + K + SG P A +
Sbjct: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1363
Query: 1461 ------AVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFR- 1513
EA +SP EK KG+ + S + K+K G G +
Sbjct: 1364 KKKLGAGEGGEASVSP---EKT-----STTSKGKAKRDKASGDVKEKKGKGSLGSQGAKD 1415
Query: 1514 ------KSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENE 1567
+ + + K+K EKK + +RKK+K+K E + + +
Sbjct: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKS-----------DKRKKDKEKKEKKKKAKKA 1464
Query: 1568 LIKDTKSADNPDGGLQSKNNRRT 1590
KD++S + K +T
Sbjct: 1465 STKDSESPSQKKKKKKKKTAEQT 1487
Score = 46.2 bits (108), Expect = 3e-04
Identities = 113/528 (21%), Positives = 191/528 (36%), Gaps = 86/528 (16%)
Query: 549 KLCPSVQTPQVQR--ERGPQG-QGHGRMALNLQLSDTDDNETFDELHIESSDEKSPSDVS 605
K+ P V+ PQ RGP G+ + T E ES E+ ++
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLA 885
Query: 606 LAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKRTSSEE 665
+ K+ + L +S P + P P +T P KQ +SSEE
Sbjct: 886 QVKPSGKTHQIRAALAPAKES----PRKGAAPTP-PGKTGPSAAQAGKQDD--SGSSSEE 938
Query: 666 CVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAA 725
D++ P +S Q V+ + N +PAGP A Q A PR A
Sbjct: 939 S-----DSDGEAPAAVTSAQ--VIKPPLIFVDPNRSPAGPAATPA----QAQAASTPRKA 987
Query: 726 ARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRT-VTQNPQQQKLVKPTHNISCQS 784
+ + S ++E D +P + RT V P + P +++ S
Sbjct: 988 RASESTARSSSSESEDE------DVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 1041
Query: 785 NSRSSAPMGIYQKQN--LTKIPPRGKSS-----------PQKSKLMEPEATTLLPSSGLV 831
+S+ S+ + +KQ T++ + +S QK+ +P PSSG+
Sbjct: 1042 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD 1101
Query: 832 TLEKS-PALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKS 890
+ + PA +P S K + +LR P +P ++ +++ P D
Sbjct: 1102 SAVGTLPATSPQSTSVQAKGTN-----KLRK-PKLP----EVQQATKAPESSD------- 1144
Query: 891 QTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPA 950
+S DS + + E G GP+ + + P P R+ +L+ A
Sbjct: 1145 -----------DSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVE------ETA 1187
Query: 951 PSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMP 1010
S++ + PS++ + + +P L P S T PSV+ P
Sbjct: 1188 AESSEDDVVAPSQSLLSGYMTPGL----TPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
Query: 1011 SPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQ 1058
EA Q +P + A G +P++ P++ G PQ
Sbjct: 1244 KQEAKPQQAAGMLSPKTGGKEAASG---TTPQK---SRKPKKGAGNPQ 1285
Score = 41.6 bits (96), Expect = 0.007
Identities = 99/509 (19%), Positives = 181/509 (35%), Gaps = 51/509 (10%)
Query: 783 QSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPG 842
+S+S AP + Q + PP P +S P+ T ++ A +
Sbjct: 938 ESDSDGEAPAAVTSAQVIK--PPLIFVDPNRS-----------PAGPAATPAQAQAASTP 984
Query: 843 KLSRFMKTESSGPLFELRSDPHIPKHSAQLP----HSSRMPSRRDWVQCPKSQTPGSRSR 898
+ +R ++ + E + IP P + MP+ + PK+ G+ S
Sbjct: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI-APKASMAGASS- 1042
Query: 899 PAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSET 958
S +S + G + K+P+ P ++ +LA+ + + P + T+ +
Sbjct: 1043 ----SKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSS 1098
Query: 959 RVPSETARTPFKSPLLKGISAPVISS--NPATTEVQRKKPSVAFKKPIFTHPMP-SPEAV 1015
V S P SP + A + P EVQ+ A K P + S ++
Sbjct: 1099 GVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ-----ATKAPESSDDSEDSSDSS 1153
Query: 1016 IQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKT---SPRQTLGTPQRDI--GLQTPRISP 1070
+ P + + LGP + V +T S + P + + G TP ++P
Sbjct: 1154 SGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTP 1213
Query: 1071 STHEPLEMT----SSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAK 1126
+ + + T SS SVS + + KP SP + ++S ++P K
Sbjct: 1214 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1273
Query: 1127 SHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPG--KHEKDSLNEASKSSVA 1184
S G + L + + + L+ P L ++ K + L + K V
Sbjct: 1274 SRKPKKGAGNPQASTLALQSNI-TQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD 1332
Query: 1185 VNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQ-EPLESSIPGSDGR 1243
K +++ + P S+ + L G E ++ E ++ G R
Sbjct: 1333 TTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1392
Query: 1244 DGVDNRSMRRSLSSSKPHLKPALGMNGAK 1272
D + S + K +LG GAK
Sbjct: 1393 D-------KASGDVKEKKGKGSLGSQGAK 1414
Score = 38.5 bits (88), Expect = 0.063
Identities = 97/462 (20%), Positives = 154/462 (33%), Gaps = 56/462 (12%)
Query: 713 LPQGIACLQPRAAARDYTFFK-RSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQ---NP 768
L QG A + P T K +ED+E + + + + + +S TQ NP
Sbjct: 735 LGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 769 QQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSS 828
+ IS ++A + + K P R +PQ S ++ +PS
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR---NPQNSTVLA-RGPASVPSV 850
Query: 829 GLVTLEKSPA-LAPGKLSRFMKTESSGP-----LFELRSDPHIPKHSAQLPHSSRMPSRR 882
G + A P + S + ES L +++ + A L + P R+
Sbjct: 851 GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP-RK 909
Query: 883 DWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPP-----PGRSV 937
P +T G + A + DSG + G P A + PP P RS
Sbjct: 910 GAAPTPPGKT-GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 968
Query: 938 SLLARPSYDYSPAPS-STKSETRVPSETART-----------PFKSPLLKGISAPVISSN 985
A P+ + A + ST + R TAR+ P L GI V++
Sbjct: 969 ---AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 1025
Query: 986 PATTEVQRK------KPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKV 1039
A + K S + P + + PA P + + L
Sbjct: 1026 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKAS 1085
Query: 1040 SPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTP 1099
+ V +T P + + + P+T +K + RK +L +
Sbjct: 1086 EAQPPVARTQPSSGVDSAVGTL--------PATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1137
Query: 1100 PKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKG 1141
P ES SS SSS + P G +SAH G
Sbjct: 1138 KAP------ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG 1173
Score = 37.0 bits (84), Expect = 0.18
Identities = 76/352 (21%), Positives = 121/352 (34%), Gaps = 43/352 (12%)
Query: 1156 SPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA 1215
+P+L +S+V G S+ E +K+ +PA+ + A + P A
Sbjct: 102 TPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSA 161
Query: 1216 QGSLADGLPLETALQEPL----ESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGA 1271
+ S L ET + + ++ PG D+ S S SS + ++ + A
Sbjct: 162 EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPA 221
Query: 1272 KARSHSFSTHSGDKPSTPPIEGS-GKVRTQI---ITNTAERGNSLTRQNSSTESSPNKAP 1327
+ ++ S ST P G G V Q+ A+R ++ S+E
Sbjct: 222 QVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 1328 SAP----------------MLESLPSVGRPSGHPSSGKGSL----GSSGSFSSQ--HGSP 1365
AP S P+ G P GKG+ G +G+ +SQ G P
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTP------GKGATPAPPGKAGAVASQTKAGKP 335
Query: 1366 SKLPLRIPPKSEGL--LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTP---TD 1420
+ +S P K QA G+ A S R+ P P T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 1421 CPEALQSPGRTQH--PSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
A G+ + S+ E S + + + P A A S+ A SP
Sbjct: 396 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 62.4 bits (150), Expect = 4e-09
Identities = 190/875 (21%), Positives = 298/875 (34%), Gaps = 159/875 (18%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLV-------KP------THNISCQSNSRSSAPMGIYQKQ 798
PR S E ++ T+ +++ V KP + S + S SS + K
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 799 NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLV----TLEKSPALAPGKLSRFMKTESSG 854
++ P + K+S +K E A P+ G V K AL P K ++ + ES
Sbjct: 217 SVK--PAQVKASSVSTK--ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 855 PLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDE 914
S+ P + +S + P TPG + PA PP +
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA--------PPGKAG 324
Query: 915 HCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSET-----ARTPF 969
S +AG P S S + S + +PA + + + +T A P
Sbjct: 325 AVASQTKAG-----KPEEDSESSSEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPA 378
Query: 970 KSPLLKGIS-APVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSS 1028
K KG + AP + PA + Q K + S E+ + PA A S
Sbjct: 379 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS-------SEESDSEEEAPAQAKPSG 431
Query: 1029 FTVM---ALGPPKVSPKRGVPKTSPRQT-LGTPQRDIGLQ------TPRISPSTHEPLEM 1078
A P K SP++G PR+T Q +G Q + S S E L
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1079 TSSKSVSPGRKGQLNDSAST-----------PPKPSFLGVNESPSSQV-------SSSSS 1120
++ V P K AST P P +G +PS+QV SSS
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG-PATPSAQVGKWEEDSESSSE 550
Query: 1121 SSSPAKSHNSPHGCQSAHEKGLKTRLPV-GLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SS + P A EK L L K P V K EK N S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 1180 KSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA------QGSLADGLPLETALQEPL 1233
+ + + PA+M + + +P ++A + A P+ Q P
Sbjct: 611 SEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 1234 ES-----------SIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHS 1282
++ ++ G R D+ S S S + K L + +A+S
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE---KTGLAVTVGQAKSVGKGLQV 724
Query: 1283 GDKPSTPPIEGS-------------GKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA 1329
K ++ P++GS G TQ+ E S ++ S E++ + A
Sbjct: 725 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 1330 PMLESLPSVGRP-SGHPSSGKGSLGSSG-----SFSSQHGSPSKL--PLRIPPKSEGLLI 1381
++ + P + S KG++ + G + ++ SPSK+ P+R P S L
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
Query: 1382 PP------------------GKEDQQAFTQGECPS-------ANVAVLGEPGSDRRSCPP 1416
P G E+ ++ E S A V G+ R + P
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 1417 TPTDCPE---ALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIE 1473
+ P A PG+T PS + +S D+ A AV+S + P
Sbjct: 903 A-KESPRKGAAPTPPGKT-GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP-- 958
Query: 1474 EKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFAS 1508
++ + N P +A P + AS
Sbjct: 959 ---LIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
Score = 53.1 bits (126), Expect = 2e-06
Identities = 162/825 (19%), Positives = 287/825 (34%), Gaps = 148/825 (17%)
Query: 876 SRMPSRRDWVQCPKSQTP---GSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPP 932
++ P + P +P G RPA +SS S E + +E G G
Sbjct: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 933 PGRSVSLLARPSYDYSPAP----------SSTKSETRVPSETARTPFKSPLLKGISAPVI 982
++ S+ + S AP + K+E + SE++ S A V
Sbjct: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 983 SS--------NPATTEVQRKKPSVAFKKPIFTHPMPSPE-AVIQTRCPAHAPSSSFTVMA 1033
+S NPA K +++ + T + + + + + P P +S TV+A
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS-TVLA 841
Query: 1034 LGPPKVSPKRGVPKTSPRQTLGTPQRDIG--------------LQTPRISPSTHE----- 1074
GP V P G + Q P+ D G L + S TH+
Sbjct: 842 RGPASV-PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 1075 -PLEMTSSKSVSP----------GRKGQLNDSASTP--------------------PKPS 1103
P + + K +P + G+ +DS S+ P
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 1104 FLGVNESPSSQVSS---SSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLL 1160
F+ N SP+ ++ + ++S+P K+ S +S+ + + + L +P +
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL--TPGIR 1018
Query: 1161 RKSSTVPGKHE----KDSLNEASKSSVAVNKSKPEDSKNPAS-MEITAGERNVTLPDS-- 1213
T+P H K S+ AS S + S + + PA+ ++ G T P S
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTS 1078
Query: 1214 -QAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAK 1272
QA+G+ P +Q+ ++ D D D+ S K A +
Sbjct: 1079 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1138
Query: 1273 ARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPML 1332
+R+ + + + S + + +++ G LT NS + K S+P +
Sbjct: 1139 SRTETLVEETAAESSEDDVVAPSQ---SLLSGYMTPG--LTPANSQASKATPKLDSSPSV 1193
Query: 1333 ESLPSV-----GRPSGHPSSGKGSLG--SSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGK 1385
S + G+ P G L + G ++ +P K R P K G
Sbjct: 1194 SSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS--RKPKKGAG------- 1244
Query: 1386 EDQQAFTQGECPSANVAVLGEPG--SDRRSCPPTPTDCPEALQSPGRTQHPSTFETS--- 1440
+ QA T + +LG+P ++ + E L+ + +T E+S
Sbjct: 1245 -NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKG 1303
Query: 1441 -STSKLETSGRHPDASATATD-------AVSSEAPLSPTIEEKVMLCIQENVEKGQVQTK 1492
+ K + SG P A + EA +SP EK KG+ +
Sbjct: 1304 WESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP---EKT-----STTSKGKAKRD 1355
Query: 1493 PTSVEAKQKPGPSFASWFGFR-------KSRLPALSSRKMDISKTKVEKKDAKVLGFGNR 1545
S + K+K G G + + + + K+K EKK +
Sbjct: 1356 KASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKS-------- 1407
Query: 1546 QLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRT 1590
+RKK+K+K E + + + KD++S + K +T
Sbjct: 1408 ---DKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1449
Score = 43.1 bits (100), Expect = 0.003
Identities = 76/368 (20%), Positives = 127/368 (34%), Gaps = 40/368 (10%)
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSS-GLVTLEKSPALAPGKLSRFMKTESSGPLFELRSD 862
P + K+S +K++ A PS+ G ++ A + + ++ P+ ++
Sbjct: 778 PAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS 837
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGE---------PPTRD 913
+ + A +P + + Q + GS E SDS E P +
Sbjct: 838 TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE----EESDSEEEAETLAQVKPSGKT 893
Query: 914 EHCGSGPEAGVKSP---SPPPPPGRSVSLLARPSYDYSPAPSSTKSET--RVPSETARTP 968
+ +SP + P PPG++ A+ SS +S++ P+
Sbjct: 894 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 969 FKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSP-------EAVIQTRCP 1021
P L + + PA T Q + S K S + + T+C
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 1022 AHAPSSSFTVMALGPPKVSPKRGVP-----KTSPRQTLGTPQRDIGLQTPRISPSTHEPL 1076
++ M P+++PK + K S R + G Q Q S L
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVD----SAVGTL 1069
Query: 1077 EMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS---PHG 1133
TS +S S KG + P P ++P S S SS S + S P G
Sbjct: 1070 PATSPQSTSVQAKG--TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
Query: 1134 CQSAHEKG 1141
+SAH G
Sbjct: 1128 AKSAHTLG 1135
Score = 37.0 bits (84), Expect = 0.18
Identities = 76/352 (21%), Positives = 121/352 (34%), Gaps = 43/352 (12%)
Query: 1156 SPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA 1215
+P+L +S+V G S+ E +K+ +PA+ + A + P A
Sbjct: 102 TPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSA 161
Query: 1216 QGSLADGLPLETALQEPL----ESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGA 1271
+ S L ET + + ++ PG D+ S S SS + ++ + A
Sbjct: 162 EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPA 221
Query: 1272 KARSHSFSTHSGDKPSTPPIEGS-GKVRTQI---ITNTAERGNSLTRQNSSTESSPNKAP 1327
+ ++ S ST P G G V Q+ A+R ++ S+E
Sbjct: 222 QVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 1328 SAP----------------MLESLPSVGRPSGHPSSGKGSL----GSSGSFSSQ--HGSP 1365
AP S P+ G P GKG+ G +G+ +SQ G P
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTP------GKGATPAPPGKAGAVASQTKAGKP 335
Query: 1366 SKLPLRIPPKSEGL--LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTP---TD 1420
+ +S P K QA G+ A S R+ P P T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 1421 CPEALQSPGRTQH--PSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
A G+ + S+ E S + + + P A A S+ A SP
Sbjct: 396 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Score = 33.1 bits (74), Expect = 2.7
Identities = 137/719 (19%), Positives = 242/719 (33%), Gaps = 83/719 (11%)
Query: 602 SDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPI------------PSETRPKTF 649
S S +D+++ L V VG KS+ + + VP+ P +T P T
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP-TV 751
Query: 650 SFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPA-GPKAE 708
+ +K ++ SSEE D E S Q +V + + N A P A+
Sbjct: 752 TQVKAEKQEDSESSEE-------ESDSEEAAASPAQVKT-SVKKTQAKANPAAARAPSAK 803
Query: 709 HTELLPQGIACLQPRAAARDYTFFKRSEEDTEKN-IPKDNVDNVPRVSTESFSSRTVTQN 767
T P + +A R + K + + + + +VP V ++
Sbjct: 804 GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTG 863
Query: 768 PQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKS-------SPQKSKLMEPE 820
P++ S S + + L ++ P GK+ +P K +
Sbjct: 864 PEED------------SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
Query: 821 ATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPS 880
A T +G + G S ++ P + P P+ S
Sbjct: 912 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGP 971
Query: 881 RRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEA---GVKS-----PSPPPP 932
Q + TP ++R + ++ S + DE + G+++ P+ P
Sbjct: 972 AATPAQAQAASTP-RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 933 PGRSVSLLARPSYDYSPAPSSTKSE----TRVPSETARTPFKSPLLKGISAPVISS--NP 986
S+ S S S K + T+V S P SP + A + P
Sbjct: 1031 IAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1090
Query: 987 ATTEVQRKKPSVAFKKPIFTHPMP-SPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGV 1045
EVQ+ A K P + S ++ + P + + LGP + V
Sbjct: 1091 KLPEVQQ-----ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV 1145
Query: 1046 PKT---SPRQTLGTPQRDI--GLQTPRISPSTHEPLEMT----SSKSVSPGRKGQLNDSA 1096
+T S + P + + G TP ++P+ + + T SS SVS + +
Sbjct: 1146 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1205
Query: 1097 STPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKS 1156
KP SP + ++S ++P KS G + L + + + L+
Sbjct: 1206 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI-TQCLLGQ 1264
Query: 1157 PQLLRKSSTVPG--KHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQ 1214
P L ++ K + L + K V K +++ + P S+
Sbjct: 1265 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1324
Query: 1215 AQGSLADGLPLETALQ-EPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAK 1272
+ L G E ++ E ++ G RD + S + K +LG GAK
Sbjct: 1325 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRD-------KASGDVKEKKGKGSLGSQGAK 1376
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 61.6 bits (148), Expect = 7e-09
Identities = 176/879 (20%), Positives = 307/879 (34%), Gaps = 142/879 (16%)
Query: 704 GPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRT 763
G A H E +P G + ++D T KR + PK+ VD + + +++S
Sbjct: 1603 GSSAHHQEGVPNGTG----QKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVV 1658
Query: 764 VTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATT 823
+ + + +++ QSN + K+ ++ + ++ +
Sbjct: 1659 IIDDHPEVTVIEDP-----QSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKN 1713
Query: 824 LLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRD 883
T + P A + + + +SS + L S P P SA +P S+ P
Sbjct: 1714 ANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT 1773
Query: 884 WVQCPKSQT---PGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLL 940
P S + P S P + S+ + P SP P SVS
Sbjct: 1774 LTPVPASTSAPVPASTLAPVLASTSAPVPA---------------SPLAPVSASASVS-- 1816
Query: 941 ARPSYDYSPAPSSTKSETRVPSET-ARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVA 999
+ P+ST + S A P +P+L +S P + A+ + P +A
Sbjct: 1817 -------ASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASI----PILA 1865
Query: 1000 FKKPIFTHPMPSPEA-------VIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQ 1052
+ P P+P A + PA AP++S + +P P ++P
Sbjct: 1866 SALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAP-APTPVSAPNP 1924
Query: 1053 TLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPS 1112
P + TH+P++ Q +S P PS PS
Sbjct: 1925 APPAP--------AQTQAQTHKPVQ----------NPLQTTSQSSKQPPPSI----RLPS 1962
Query: 1113 SQVSSSSSSSSPAKSHNSP--HGCQSAHEKGLKTRLPVGLKVLMK-----SPQLLRKSST 1165
+Q + + + KS +P HG +A K P L + K SP + S
Sbjct: 1963 AQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPP--QPPSV 2020
Query: 1166 VPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITA----GERNVTLPDSQAQGSLAD 1221
S A S A N + +++ A G N +P + +
Sbjct: 2021 SAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKI 2080
Query: 1222 GLPLETALQEPLESSIPGSDGRD--GVDNRSMR-------RSLSSSKPHLKPALGMNGAK 1272
P E ++P I D V+N+ + RSL + K +K A +
Sbjct: 2081 PEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRK--VKDAQQVEPEG 2138
Query: 1273 ARSHSFSTHSGDKPSTPP-----IEGSGKVRTQIITNTAERG----NSLTRQNSSTESSP 1323
S +T P T E S ++ T I ++AE G S+T + + S P
Sbjct: 2139 QEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLP 2198
Query: 1324 NK-APSAPMLES--LPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLL 1380
N A + +E + +V P+ P + ++ S S +S +PP + L
Sbjct: 2199 NTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTS-----------VPPTTFSLT 2247
Query: 1381 IPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETS 1440
++ + S NV G P + + PP T + P T + ++F ++
Sbjct: 2248 F-----KMESARKAWENSPNVREKGSPVTS--TAPPIATGVSSSASGPS-TANYNSFSSA 2299
Query: 1441 STSKLETSGRHPDA--SATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEA 1498
S ++ + P A S T SS + S T + +C + KP ++
Sbjct: 2300 SMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNIC----------KVKPQQLQT 2349
Query: 1499 KQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDA 1537
P S S + S +P+L +++ + V + A
Sbjct: 2350 SSLPSASHFS----QLSCMPSLIAQQQQNPQVYVSQSAA 2384
Score = 40.8 bits (94), Expect = 0.013
Identities = 72/353 (20%), Positives = 138/353 (39%), Gaps = 39/353 (11%)
Query: 1303 TNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQH 1362
+N+ + NS + + ++E++ NK + + + S P+ PS K G SF+ +
Sbjct: 342 SNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPA-QPSVAKVPYGKGPSFNQER 400
Query: 1363 GSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCP 1422
G+ S LP PP K Q P AV G PG P P+
Sbjct: 401 GTSSHLP------------PPPK----LLAQQHPPPDRQAVPGRPG-------PFPSKQQ 437
Query: 1423 EALQSP-GRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQ 1481
A + + + E S+ + R + ++ A ++EK+ +
Sbjct: 438 VADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI--- 494
Query: 1482 ENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLG 1541
+EK Q P + +++ ++ R+ D + + ++K+ +
Sbjct: 495 --LEK---QPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
Query: 1542 FGNRQLKSERKKEKKKP-ELQCETENEL--IKDTKSADNPDGGLQSKNNRRTPQDIYNQL 1598
R+++ ERK+EK+K E Q E E EL +K+ + + + + P++ +
Sbjct: 550 EKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEP 609
Query: 1599 KIEPRNRHSPVACSTKDTFMTELLNRVDKKAAP---QTESGSSNASCRNVLKG 1648
+E + + + F + NR +K+A P +TE S + VL G
Sbjct: 610 MVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSG 662
Score = 37.7 bits (86), Expect = 0.11
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 38 QLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRL-QEVTL 96
++EEQ ++ EKL RL ++ + + E E E+ER + EK QE
Sbjct: 472 RMEEQRKAACAEKLK--RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREK 529
Query: 97 ESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQK-------KEETVNIMVYQEKLSEE 149
E E++R + + +++ + +E R + + + ++K KE+ + M QEK E
Sbjct: 530 EREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECEL 589
Query: 150 ERKHKEALED 159
E K +E LE+
Sbjct: 590 E-KEREKLEE 598
Score = 35.4 bits (80), Expect = 0.54
Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 29/207 (14%)
Query: 57 QREVAQRTSEGAMHEKLIHELEEERHLRLQSE-------KRLQEVT--LESERNRIQMRS 107
QR Q A+ EEER + Q + KRL E LE + + ++R
Sbjct: 447 QRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRE 506
Query: 108 LQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALE---DLHMVV 164
+++ R E L+ + E++KE +EK E +++ ++ LE + +
Sbjct: 507 REREKEREREKE---LEKEQEQEREKE--------REKDRERQQEKEKELEKEQEKQREM 555
Query: 165 DEDSRSESSSTDEGKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQA 224
+++ + E E +++ + L+++K E E E E +RE+ E + E ++
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKE-----CELEKEREKLEEKI-EPREPNLEP 609
Query: 225 LLTQKDLREECVKLKTRVFDLEQQNRT 251
++ +++ C K + VF + NR+
Sbjct: 610 MVEKQESENSCNKEEEPVFTRQDSNRS 636
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 60.8 bits (146), Expect = 1e-08
Identities = 70/310 (22%), Positives = 138/310 (44%), Gaps = 40/310 (12%)
Query: 33 EHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQ 92
+ L Q EE L REK A+ + +RE A++ + + ++ ++ + L + + +
Sbjct: 743 QRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERE 802
Query: 93 EVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQ---GSPEQKKEETVNIMVYQEKLSEE 149
+ ++ R R ++ L+QQ + L+++ G EQ++ + + +++L E
Sbjct: 803 RLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQL-EL 861
Query: 150 ERKHKEA----LEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLK---ALEAENSALALE 202
ER+ EA E+ ++ E E KE +L++ RL+ AL E S A E
Sbjct: 862 ERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKE-IELVIHRLEADMALAKEESEKAAE 920
Query: 203 N--ENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV 260
+ + R++YE L E+ +++ L+E C +LK ++ + E +N L L +Q+
Sbjct: 921 SRIKRLRDKYEAELSELEQ-------SERKLQERCSELKGQLGEAEGENLRLQGLVRQKE 973
Query: 261 RPTSD-----------------LLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDAEVH 303
R D ++ Q+ RL +S + + + + Q+R E+
Sbjct: 974 RALEDAQAVNEQLSSERSNLAQVIRQEFEDRL--AASEEETRQAKAELATLQARQQLELE 1031
Query: 304 EHQLNTKSAL 313
E K+AL
Sbjct: 1032 EVHRRVKTAL 1041
Score = 35.0 bits (79), Expect = 0.70
Identities = 58/279 (20%), Positives = 118/279 (42%), Gaps = 48/279 (17%)
Query: 49 EKLAVARLQREVAQRTSEGAMHEKLIHELEEER------------HLRLQSEKRLQEVTL 96
EK +LQR+ + H I +L E++ L+ + ++ + V
Sbjct: 606 EKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQ 665
Query: 97 ESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEA 156
++ ++++ L++ S E+ R S+ + + K+ + +KL ++
Sbjct: 666 AQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRR 725
Query: 157 LEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA-LENENQREQYERC 213
L+ LH ++ D R+ + +E + LE E AL E E R+++++
Sbjct: 726 LKSLHEAELLQSDERASQRCLRQAEELR-------EQLEREKEALGQQERERARQRFQQH 778
Query: 214 LDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHS 273
L++ Q L+++ +L + V E++ R L QQ R ++ L++L
Sbjct: 779 LEQ----------EQWALQQQRQRLYSEV--AEERER----LGQQAARQRAE--LEELRQ 820
Query: 274 RLLDLSSG---DLLSEVERNRSLTQSRTDAEVHEHQLNT 309
+L + SS L +E E+ R + R H+ +LNT
Sbjct: 821 QLEESSSALTRALRAEFEKGREEQERR-----HQMELNT 854
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 60.5 bits (145), Expect = 2e-08
Identities = 89/335 (26%), Positives = 125/335 (37%), Gaps = 50/335 (14%)
Query: 805 PRGKSSPQKSKLMEPEATTLLPSSGLVTLEK--SPALAPGKLSRFMKTESSGPLFELRSD 862
P+ +S+ + LLP G T K SP PG+ S G RS
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP----VPSPGH----RSG 160
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESS--DSGEPPTRDEHCGSGP 920
P P+ + P + S+ D + P TP RP I+SS + G PP GP
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP----RP-IQSSPHNRGSPPVP-----GGP 210
Query: 921 EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETR--VPSETARTPFKSPLLKGIS 978
P+PPP PG + L S SP SS+ R +P +R P
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP---PPP 267
Query: 979 APVISSNPATTEVQRKKPSVAFKKPIFTHPMPS---PEAVIQTRCPAHAPSSSFTVMALG 1035
P + + P+ P KP P+PS P A Q P PS G
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKP----PVPSTPRPSASSQAPPPPPPPSRP------G 317
Query: 1036 PPKVSPKRGVPKTSPRQTLGTPQRDIGLQT---PRISPSTHEPLEMTSSKSVSPGRKGQL 1092
PP + P +PR PQR++ L + P SP PL S+ P +
Sbjct: 318 PPPLPPSSSGNDETPR----LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373
Query: 1093 NDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKS 1127
S PP P V+ + S+ + ++ P++S
Sbjct: 374 GRSGPLPPPPP---VSRNGSTSRALPATPQLPSRS 405
Score = 41.6 bits (96), Expect = 0.007
Identities = 81/331 (24%), Positives = 111/331 (33%), Gaps = 67/331 (20%)
Query: 1037 PKVSP-KRGVPKTSPRQTLGTPQRDIGLQTPRISP---STHEPLEMTSSKSVSP---GRK 1089
P SP R P R + P+ D+G + I P ST P++ + SP G
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1090 GQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS--PHGCQSAHEKGLKTRLP 1147
Q + + PP P G S S SSSSP + P ++ +K P
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270
Query: 1148 VGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERN 1207
VG N S AV P+++K P +
Sbjct: 271 VG--------------------------NRPSIHREAVPPPPPQNNKPPVP--------S 296
Query: 1208 VTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALG 1267
P + +Q P PL S G+D + R++ SLSSS P L P+ G
Sbjct: 297 TPRPSASSQAPPPPPPPSRPG-PPPLPPSSSGNDETPRLPQRNL--SLSSSTPPL-PSPG 352
Query: 1268 MNGAKARSHSFST---------HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQ--N 1316
+G S SG P PP+ +G + R T Q +
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG---------STSRALPATPQLPS 403
Query: 1317 SSTESSPNKAPSAPMLESLPSVGRPSGHPSS 1347
S SP P P+ PS G P P S
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 34.7 bits (78), Expect = 0.92
Identities = 54/224 (24%), Positives = 77/224 (34%), Gaps = 38/224 (16%)
Query: 1232 PLESSIPGSDGRDGVDNRSMRRS-LSSSKPHL-KPALGMNGAKARSHSFSTHSGDKPSTP 1289
P PG+ G + S+R+S LSSS P +P L ++A P P
Sbjct: 217 PTPPPFPGNRGT-ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK------PPPPPP 269
Query: 1290 PIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGK 1349
P+ + + + + N ++ S+ ++AP P S P G P PSS
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP--GPPPLPPSSSG 327
Query: 1350 G---------------------SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQ 1388
S G SG P+R PP G L PP +
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
Query: 1389 QAFTQGECPSA----NVAVLGEPGSDRRSCPPTPTDCPEALQSP 1428
T P+ + + + P S R PP P D P A P
Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPR--PPLPPDRPSAGAPP 429
Score = 32.3 bits (72), Expect = 4.5
Identities = 44/155 (28%), Positives = 56/155 (36%), Gaps = 17/155 (10%)
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPAL-APGKLSRFMKTESSGPLFELRSD 862
P R P + T LP L +P L +PG+ S P +R D
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR-D 371
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSG-EPPTRDEHCGSGPE 921
P P S LP + SR TP SR ++S SG PP + P
Sbjct: 372 P--PGRSGPLPPPPPV-SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR----PS 424
Query: 922 AGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKS 956
AG PPPPP S+ R + SP +S
Sbjct: 425 AGAP---PPPPPSTSI----RNGFQDSPCEDEWES 452
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 60.5 bits (145), Expect = 2e-08
Identities = 89/335 (26%), Positives = 125/335 (37%), Gaps = 50/335 (14%)
Query: 805 PRGKSSPQKSKLMEPEATTLLPSSGLVTLEK--SPALAPGKLSRFMKTESSGPLFELRSD 862
P+ +S+ + LLP G T K SP PG+ S G RS
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP----VPSPGH----RSG 160
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESS--DSGEPPTRDEHCGSGP 920
P P+ + P + S+ D + P TP RP I+SS + G PP GP
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP----RP-IQSSPHNRGSPPVP-----GGP 210
Query: 921 EAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETR--VPSETARTPFKSPLLKGIS 978
P+PPP PG + L S SP SS+ R +P +R P
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP---PPP 267
Query: 979 APVISSNPATTEVQRKKPSVAFKKPIFTHPMPS---PEAVIQTRCPAHAPSSSFTVMALG 1035
P + + P+ P KP P+PS P A Q P PS G
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKP----PVPSTPRPSASSQAPPPPPPPSRP------G 317
Query: 1036 PPKVSPKRGVPKTSPRQTLGTPQRDIGLQT---PRISPSTHEPLEMTSSKSVSPGRKGQL 1092
PP + P +PR PQR++ L + P SP PL S+ P +
Sbjct: 318 PPPLPPSSSGNDETPR----LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373
Query: 1093 NDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKS 1127
S PP P V+ + S+ + ++ P++S
Sbjct: 374 GRSGPLPPPPP---VSRNGSTSRALPATPQLPSRS 405
Score = 41.6 bits (96), Expect = 0.007
Identities = 81/331 (24%), Positives = 111/331 (33%), Gaps = 67/331 (20%)
Query: 1037 PKVSP-KRGVPKTSPRQTLGTPQRDIGLQTPRISP---STHEPLEMTSSKSVSP---GRK 1089
P SP R P R + P+ D+G + I P ST P++ + SP G
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1090 GQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNS--PHGCQSAHEKGLKTRLP 1147
Q + + PP P G S S SSSSP + P ++ +K P
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270
Query: 1148 VGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERN 1207
VG N S AV P+++K P +
Sbjct: 271 VG--------------------------NRPSIHREAVPPPPPQNNKPPVP--------S 296
Query: 1208 VTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALG 1267
P + +Q P PL S G+D + R++ SLSSS P L P+ G
Sbjct: 297 TPRPSASSQAPPPPPPPSRPG-PPPLPPSSSGNDETPRLPQRNL--SLSSSTPPL-PSPG 352
Query: 1268 MNGAKARSHSFST---------HSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQ--N 1316
+G S SG P PP+ +G + R T Q +
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG---------STSRALPATPQLPS 403
Query: 1317 SSTESSPNKAPSAPMLESLPSVGRPSGHPSS 1347
S SP P P+ PS G P P S
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 34.7 bits (78), Expect = 0.92
Identities = 54/224 (24%), Positives = 77/224 (34%), Gaps = 38/224 (16%)
Query: 1232 PLESSIPGSDGRDGVDNRSMRRS-LSSSKPHL-KPALGMNGAKARSHSFSTHSGDKPSTP 1289
P PG+ G + S+R+S LSSS P +P L ++A P P
Sbjct: 217 PTPPPFPGNRGT-ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK------PPPPPP 269
Query: 1290 PIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGK 1349
P+ + + + + N ++ S+ ++AP P S P G P PSS
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP--GPPPLPPSSSG 327
Query: 1350 G---------------------SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQ 1388
S G SG P+R PP G L PP +
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
Query: 1389 QAFTQGECPSA----NVAVLGEPGSDRRSCPPTPTDCPEALQSP 1428
T P+ + + + P S R PP P D P A P
Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPR--PPLPPDRPSAGAPP 429
Score = 32.3 bits (72), Expect = 4.5
Identities = 44/155 (28%), Positives = 56/155 (36%), Gaps = 17/155 (10%)
Query: 804 PPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPAL-APGKLSRFMKTESSGPLFELRSD 862
P R P + T LP L +P L +PG+ S P +R D
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR-D 371
Query: 863 PHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSG-EPPTRDEHCGSGPE 921
P P S LP + SR TP SR ++S SG PP + P
Sbjct: 372 P--PGRSGPLPPPPPV-SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR----PS 424
Query: 922 AGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKS 956
AG PPPPP S+ R + SP +S
Sbjct: 425 AGAP---PPPPPSTSI----RNGFQDSPCEDEWES 452
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 60.5 bits (145), Expect = 2e-08
Identities = 100/406 (24%), Positives = 146/406 (35%), Gaps = 34/406 (8%)
Query: 808 KSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPK 867
K Q +K +P + LP + + + LS M+T+ G + P PK
Sbjct: 94 KPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALS--METQKLGSVLS----PESPK 147
Query: 868 HSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESS-DSGEPPTRDEHCGSGPEAGVKS 926
+ P + P V P+ QTP P+ +S S EPP C S A V S
Sbjct: 148 PTPLTPLEPQKPGS---VVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPS 204
Query: 927 PSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNP 986
P P P S + + P S ET P +A +P +SP+L P +P
Sbjct: 205 PEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPP-SASSP-ESPVLAASPEPW-GPSP 261
Query: 987 ATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVP 1046
A + RK +P P SPE PA +P A+ P P P
Sbjct: 262 AASPESRKSARTTSPEPRKPSPSESPEP--WKPFPAVSPEPRRPAPAVSPGSWKPG---P 316
Query: 1047 KTSPRQTLGTPQRDIG-----LQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPK 1101
SPR P G P +SP +P+ SVSPG +S K
Sbjct: 317 PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP-----SVSPGPWKPTPSVSSASWK 371
Query: 1102 PSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLR 1161
S + + S S S S P + + H K + PV ++ P L
Sbjct: 372 SSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVP---PVSPELRKPGPPLSP 428
Query: 1162 KSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERN 1207
+ + G E L + S S S + +PAS++ +++
Sbjct: 429 EIRSPAGSPE---LRKPSGSPDLWKLSPDQRKTSPASLDFPESQKS 471
Score = 31.6 bits (70), Expect = 7.8
Identities = 78/357 (21%), Positives = 120/357 (33%), Gaps = 64/357 (17%)
Query: 743 IPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPM---------- 792
+P VS ES + NP+ QK + S S +P+
Sbjct: 202 VPSPEPQKPAPVSPESV--KATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGP 259
Query: 793 -----GIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLS-- 845
+K T P K SP +S PE P+ +PA++PG
Sbjct: 260 SPAASPESRKSARTTSPEPRKPSPSES----PEPWKPFPAVSPEPRRPAPAVSPGSWKPG 315
Query: 846 --------RFMKTESSGPLFELRSDPHI-PKHSAQLPHSSRMPSRRDWVQCPKSQTPGSR 896
+ + SSGP + P + P +P S P W P S + S
Sbjct: 316 PPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGP----WKPTP-SVSSASW 370
Query: 897 SRPAIESSDSGEPPTRDEHCGSG-PEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTK 955
++ S PP E SG PE +P+ P ++V ++ P P S +
Sbjct: 371 KSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVS-PELRKPGPPLSPE 429
Query: 956 SETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPS--------------VAFK 1001
+ S R P SP L +S ++PA+ + + S + +
Sbjct: 430 IRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQ 489
Query: 1002 KPIF--------THPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSP 1050
KP+F + P SP+A P + + AL P P + P SP
Sbjct: 490 KPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFP---EPAKTAPPASP 543
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 59.7 bits (143), Expect = 3e-08
Identities = 165/807 (20%), Positives = 275/807 (34%), Gaps = 110/807 (13%)
Query: 1115 VSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDS 1174
V SS + Q H+ L + PV K+ K Q K+
Sbjct: 1671 VGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQ-------------KEE 1717
Query: 1175 LNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLET------A 1228
+AS + K E+S G LP +A L + P+ + A
Sbjct: 1718 GLQASAEKAELKKGSSEESLGE-----DPGLAPEPLPTVKATSPLIEETPIGSIKDKVKA 1772
Query: 1229 LQEPLESSIPGSD-------GRDGVDNRSMRRSLSSSKPHLKP---ALGMNGAKARSHSF 1278
LQ+ +E G G++ V ++ R ++ P LK A G K HS
Sbjct: 1773 LQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHST 1832
Query: 1279 STHSGDKPSTPPIEGSGKVR--TQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLP 1336
+ S PP+ S K + + + +S +S TE +PS P
Sbjct: 1833 LSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSP 1892
Query: 1337 -SVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLL--IPPGKEDQQAFTQ 1393
S + HP S G K P P ++E L P G+ D+
Sbjct: 1893 VSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVS 1952
Query: 1394 GECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPD 1453
+ + G + P +PT E ++ T K SG+ P
Sbjct: 1953 TAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEE--------TMSVRELMKAFQSGQDPS 2004
Query: 1454 ASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFR 1513
T S P + KV + EKG + T+ EA++ + R
Sbjct: 2005 KHKTGLFEHKSAKQKQPQEKGKVRV----EKEKGPILTQR---EAQKTENQTIK-----R 2052
Query: 1514 KSRLP----ALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKE--KKKPELQCETENE 1567
RLP A S R + +S V+K+DA G ++ S + E + PE + E+E
Sbjct: 2053 GQRLPVTGTAESKRGVRVSSIGVKKEDA---AGGKEKVLSHKIPEPVQSVPEEESHRESE 2109
Query: 1568 LIKDTKSADNPDGGLQSKNNRRTPQDIYNQLK--IEPRNRHSPVACSTK--------DTF 1617
+ K+ + + D LQ +R+T D +K +E +++ S + D
Sbjct: 2110 VPKEKMADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQV 2169
Query: 1618 MTELLN--------RVDKKAAPQTESGSSNASCRNV----LKGSSQGSCLIGSSISTQGN 1665
+T N + + A +SG+ + S ++ + GS GS + G+ +
Sbjct: 2170 LTSPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEE 2229
Query: 1666 HKKNMKIKADMEVPKDSL---VKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGI 1722
K+ + E +SL K++ E E ++ ++ + + + + + G
Sbjct: 2230 SYKHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGS 2289
Query: 1723 GTFPLPDSGNRSTGRYLCQPD----SPEDAEPLL--PLQSALSAVSSMRAQTLEREVPSS 1776
+ + T Q + SP+D P + S + T E +
Sbjct: 2290 EERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAAC 2349
Query: 1777 TDGQRP-ADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSF 1835
+GQR SA T + + LP P +S K + E +PQ
Sbjct: 2350 DEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDT----GTESKPQ----- 2400
Query: 1836 GYAEDPMASQ-PLPDWGSEVAATGTQD 1861
G P + LP SEV + D
Sbjct: 2401 GVIRSPQGLELALPSRDSEVLSAVADD 2427
Score = 55.8 bits (133), Expect = 4e-07
Identities = 211/1088 (19%), Positives = 381/1088 (35%), Gaps = 160/1088 (14%)
Query: 654 QQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELL 713
+Q+ + CV V D E +E S TG+V +++ N+ PK +
Sbjct: 1604 RQKAPLEITEYPCVEVRIDKEIKGKVEKDS--TGLVNYLTDDL--NTCVPLPKEQ----- 1654
Query: 714 PQGIACLQPRAAAR-DYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQK 772
+ +Q +A + + RS E K+IP D + + S + + ++K
Sbjct: 1655 ---LQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEK 1711
Query: 773 LVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVT 832
+ + Q+++ + +++L + P K P L+ + + +
Sbjct: 1712 QKQKEEGL--QASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSP----LIEETPIGS 1765
Query: 833 LEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQT 892
++ ++ K S P+ ++ +PK + PH + PS + P S +
Sbjct: 1766 IKDKVKALQKRVEDEQKGRSKLPI-RVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPS 1824
Query: 893 PGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPS 952
P + + SS E H P + + SP P ++ +SPA S
Sbjct: 1825 PKTERHSTLSSSAKTE-----RHPPVSPSSKTEKHSPVSPSAKTER--------HSPASS 1871
Query: 953 STKSETRVP-SETARTPFKSPL--LKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPM 1009
S+K+E P S + +T SP+ K P +S + T K+P V+ HP
Sbjct: 1872 SSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTD----KRPPVSPSGRTEKHPP 1927
Query: 1010 PSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRIS 1069
SP + R P VSP K P T G ++
Sbjct: 1928 VSPGRT-EKRLP-----------------VSPSGRTDKHQPVSTAGKTEK---------- 1959
Query: 1070 PSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHN 1129
H P VSP K + S K + S + + S P+K
Sbjct: 1960 ---HLP--------VSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKT 2008
Query: 1130 SPHGCQSAHEKGLKTRLPVGLKVLMKSP------------QLLRKSSTVPGKHEKDSLNE 1177
+SA +K + + V ++ K P Q +++ +P +S
Sbjct: 2009 GLFEHKSAKQKQPQEKGKVRVE-KEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRG 2067
Query: 1178 ASKSSVAVNKSKPEDSKNPA-SMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESS 1236
SS+ V K K S +I ++V +S + +P E E +
Sbjct: 2068 VRVSSIGVKKEDAAGGKEKVLSHKIPEPVQSVPEEESHRESE----VPKEKMADEQGDMD 2123
Query: 1237 IPGS-DGRDGVD-NRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGS 1294
+ S D + D + +++ L + + + L KA+ H + +T P++
Sbjct: 2124 LQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLD-- 2181
Query: 1295 GKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGS 1354
++ + + + + +L + S+ES N+ + G P G G + S
Sbjct: 2182 -YMKDEFLPALSLQSGAL---DGSSESLKNEGVA----------GSPCGSLMEGTPQISS 2227
Query: 1355 SGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSC 1414
S+ +H ++ P P E L P K ++Q E S E S++
Sbjct: 2228 EESY--KHEGLAETPETSP---ESLSFSPKKSEEQTGETKE--STKTETTTEIRSEKEH- 2279
Query: 1415 PPTPTDCPEALQSPGRT-QHPSTFETSSTSKLETSG--------RHPDASATATDAVSSE 1465
PT D + G T S T S K T G R D + + + A++ E
Sbjct: 2280 -PTTKDITGGSEERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKE 2338
Query: 1466 APLSPTIE---EKVMLCIQENVEKGQV-----QTKPTSVEAKQKPGPSFASWFGFRKSRL 1517
P T E ++ + K Q ++ TS E K P P +
Sbjct: 2339 TPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGTESK 2398
Query: 1518 PALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADN 1577
P R + + +D++VL + + K L+ + +++D S
Sbjct: 2399 PQGVIRSPQGLELALPSRDSEVLS----AVADDSLAVSHKDSLEA---SPVLEDNSSHKT 2451
Query: 1578 PDGGLQSKNNRRTPQDIYNQLKIEPRNR------HSPV-ACSTKDTFMTELLNRVDKKAA 1630
PD S +D +EP+ + H P+ A K +TE+ + +
Sbjct: 2452 PDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLR 2511
Query: 1631 PQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANEN 1690
S ++ + L SS S L + S++ + D+ PK +++ E E
Sbjct: 2512 DPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAE- 2570
Query: 1691 LQEDEDDA 1698
EDD+
Sbjct: 2571 ----EDDS 2574
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 59.3 bits (142), Expect = 3e-08
Identities = 186/838 (22%), Positives = 290/838 (34%), Gaps = 161/838 (19%)
Query: 752 PRVSTESFSSRTVTQNPQQQKLV-------KP------THNISCQSNSRSSAPMGIYQKQ 798
PR S E ++ T+ +++ V KP + S + S SS + K
Sbjct: 157 PRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 799 NLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLV----TLEKSPALAPGKLSRFMKTESSG 854
++ P + K+S +K E A P+ G V K AL P K ++ + ES
Sbjct: 217 SVK--PAQVKASSVSTK--ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 855 PLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDE 914
S+ P + +S + P TPG + PA PP +
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA--------PPGKAG 324
Query: 915 HCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSET-----ARTPF 969
S +AG P S S + S + +PA + + + +T A P
Sbjct: 325 AVASQTKAG-----KPEEDSESSSEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPA 378
Query: 970 KSPLLKGIS-APVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSS 1028
K KG + AP + PA + Q K + S E+ + PA A S
Sbjct: 379 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS-------SEESDSEEEAPAQAKPSG 431
Query: 1029 FTVM---ALGPPKVSPKRGVPKTSPRQT-LGTPQRDIGLQ------TPRISPSTHEPLEM 1078
A P K SP++G PR+T Q +G Q + S S E L
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1079 TSSKSVSPGRKGQLNDSAST-----------PPKPSFLGVNESPSSQV-------SSSSS 1120
++ V P K AST P P +G +PS+QV SSS
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG-PATPSAQVGKWEEDSESSSE 550
Query: 1121 SSSPAKSHNSPHGCQSAHEKGLKTRLPV-GLKVLMKSPQLLRKSSTVPGKHEKDSLNEAS 1179
SS + P A EK L L K P V K EK N S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 1180 KSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA------QGSLADGLPLETALQEPL 1233
+ + + PA+M + + +P ++A + A P+ Q P
Sbjct: 611 SEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 1234 ES-----------SIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHS 1282
++ ++ G R D+ S S S + K L + +A+S
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE---KTGLAVTVGQAKSVGKGLQV 724
Query: 1283 GDKPSTPPIEGS-------------GKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSA 1329
K ++ P++GS G TQ+ E S ++ S E++ + A
Sbjct: 725 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
Query: 1330 PMLESLPSVGRP-SGHPSSGKGSLGSSG-----SFSSQHGSPSKL--PLRIPPKSEGLLI 1381
++ + P + S KG++ + G + ++ SPSK+ P+R P S L
Sbjct: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
Query: 1382 PP------------------GKEDQQAFTQGECPS-------ANVAVLGEPGSDRRSCPP 1416
P G E+ ++ E S A V G+ R + P
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 1417 TPTDCPE---ALQSPGRTQHPSTFET-------SSTSKLETSGRHPDASATATDAVSS 1464
+ P A PG+T PS + SS+ + ++ G P A +A D SS
Sbjct: 903 A-KESPRKGAAPTPPGKT-GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQDQESS 958
Score = 37.0 bits (84), Expect = 0.18
Identities = 76/352 (21%), Positives = 121/352 (34%), Gaps = 43/352 (12%)
Query: 1156 SPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQA 1215
+P+L +S+V G S+ E +K+ +PA+ + A + P A
Sbjct: 102 TPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSA 161
Query: 1216 QGSLADGLPLETALQEPL----ESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGA 1271
+ S L ET + + ++ PG D+ S S SS + ++ + A
Sbjct: 162 EPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPA 221
Query: 1272 KARSHSFSTHSGDKPSTPPIEGS-GKVRTQI---ITNTAERGNSLTRQNSSTESSPNKAP 1327
+ ++ S ST P G G V Q+ A+R ++ S+E
Sbjct: 222 QVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 1328 SAP----------------MLESLPSVGRPSGHPSSGKGSL----GSSGSFSSQ--HGSP 1365
AP S P+ G P GKG+ G +G+ +SQ G P
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTP------GKGATPAPPGKAGAVASQTKAGKP 335
Query: 1366 SKLPLRIPPKSEGL--LIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTP---TD 1420
+ +S P K QA G+ A S R+ P P T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 1421 CPEALQSPGRTQH--PSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
A G+ + S+ E S + + + P A A S+ A SP
Sbjct: 396 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 58.9 bits (141), Expect = 5e-08
Identities = 154/746 (20%), Positives = 257/746 (34%), Gaps = 147/746 (19%)
Query: 800 LTKIPPRGKSS--PQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLF 857
LT P S P+ + + P+AT+ LP + + +S A P + +S
Sbjct: 1259 LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATL---RSTATKPTVTQATTRATAST--- 1312
Query: 858 ELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCG 917
++ S+ + R + P T G+ P + S + E P
Sbjct: 1313 -----------ASPATTSTAQSTTRTTMTLPTPATSGTS--PTLPKSTNQELPGTTATQT 1359
Query: 918 SGPEAGVKSPSPP--PPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLK 975
+GP S + P P PG+ RP+ A +T++ T T +TP +
Sbjct: 1360 TGPRPTPASTTGPTTPQPGQPT----RPT-----ATETTQTRTTTEYTTPQTPHTTHSPP 1410
Query: 976 GISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPS-PEAVIQTRCPAHAPS----SSFT 1030
+PV S+ P T + +F T+P PS PE + T P + S S+ T
Sbjct: 1411 TAGSPVPSTGPVT--------ATSFHATT-TYPTPSHPETTLPTHVPPFSTSLVTPSTHT 1461
Query: 1031 VMA-------------------LGPPKVSPKRGVPKTSPR---QTLGTPQRDIGLQTPRI 1068
V+ + PP G T+P T GT Q T +
Sbjct: 1462 VITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT 1521
Query: 1069 SPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAK-- 1126
S H T V+P + + P P+ +P + +S++SS P
Sbjct: 1522 PTSLHSHTSSTHHPEVTP------TSTTTITPNPTSTRTR-TPVAHTNSATSSRPPPPFT 1574
Query: 1127 SHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQL-----------LRKSSTVPGKHEKDSL 1175
+H+ P G G T +P S P H +
Sbjct: 1575 THSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITP 1634
Query: 1176 NEASKSSVAVNKSKPEDSKNPASMEITAGERNV-------TLPDSQAQGSLADGLPLETA 1228
A ++ A S P + P + G + T SQA SL + T+
Sbjct: 1635 THAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSL-NTAKTSTS 1693
Query: 1229 LQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKA-----------RSHS 1277
L S+ N + + + + P G + +++ SH+
Sbjct: 1694 LHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHT 1753
Query: 1278 FSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPS 1337
STH + ST T I N G T +T ++ ++ P+ P P
Sbjct: 1754 SSTHHPEVTSTST--------TSITPNHTSTGTR-TPVAHTTSATSSRLPT-PFTTHSPP 1803
Query: 1338 VGRPSGHPSSGKGSL-GSSGSFSSQHGSPSK----LPLRIP--------PKSEGLLIPPG 1384
G P S G + +S ++ + +PS LP +P P + ++IP
Sbjct: 1804 TGTT---PISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860
Query: 1385 KEDQQAFTQGECPSANV---AVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSS 1441
+ + + P+ + + GS + P TPT + G +Q PS+F T+
Sbjct: 1861 TQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPT-------TSGTSQSPSSFSTAK 1913
Query: 1442 TSKL----ETSGRHPDASATATDAVS 1463
TS +S HP+ + T+T ++
Sbjct: 1914 TSTSLPYHTSSTHHPEVTPTSTTNIT 1939
Score = 47.0 bits (110), Expect = 2e-04
Identities = 172/765 (22%), Positives = 253/765 (33%), Gaps = 161/765 (21%)
Query: 759 FSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLME 818
FS+ VT P ++ PTH S S SAP G IPP
Sbjct: 1450 FSTSLVT--PSTHTVITPTHAQMATSASNHSAPTG--------TIPP------------- 1486
Query: 819 PEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDP-HIPKHSAQLPHSSR 877
T L ++G + +P + P T + F P + H++ H
Sbjct: 1487 ---PTTLKATG--STHTAPPITPTTSG----TSQAHSSFSTNKTPTSLHSHTSSTHHPEV 1537
Query: 878 MPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSV 937
P+ + + T R+R + ++S + S PPPP +
Sbjct: 1538 TPTSTTTITPNPTST---RTRTPVAHTNSA------------------TSSRPPPPFTTH 1576
Query: 938 SLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPS 997
S P SP SST T +T T + +P S+P TT P
Sbjct: 1577 S----PPTGSSPF-SSTGPMTATSFKTT-TTYPTP-----------SHPQTTLPTHVPP- 1618
Query: 998 VAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALG---PPKVSPKRGVPKTSPRQTL 1054
F + T PS VI A S+S M G PP G T+P TL
Sbjct: 1619 --FSTSLVT---PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTL 1673
Query: 1055 ---GTPQRDIGLQTPRISPSTHEPLEMT---SSKSVSPGRKGQLNDSASTPPKPSFLGVN 1108
GT Q L T + S S H T + S S S TPP + V
Sbjct: 1674 TTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPP----MTVT 1729
Query: 1109 ESPSSQVSSSSSSSSPAKSHNSPHG-CQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVP 1167
S +SQ S SS S AK+ S H S H + + + +P + P
Sbjct: 1730 TSGTSQ---SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI-----TPNHTSTGTRTP 1781
Query: 1168 GKHEKDSLNEASKSSVAVNKSKPEDSKNPAS----MEITAGERNVTLP-DSQAQGSLADG 1222
H + +S+ P P S + T+ + T P S +L
Sbjct: 1782 VAHTTSA--TSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTH 1839
Query: 1223 LP-LETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTH 1281
+P T+L P + V + + +S+ H P + + STH
Sbjct: 1840 VPSFSTSLVTPSTHT---------VIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTH 1890
Query: 1282 SGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSST---ESSPNKAPSAPMLESLPSV 1338
+ P TP G+ + + +TA+ SL SST E +P + +
Sbjct: 1891 TA-PPMTPTTSGTSQSPSSF--STAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGT 1947
Query: 1339 GRPSGH-----------------PSSGKGSLGSSG-----SFSSQHGSP------SKLPL 1370
P H P +G S+G SF + P + LP
Sbjct: 1948 RTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPT 2007
Query: 1371 RIPPKSEGLLIPPG-----KEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEAL 1425
+PP S L+ P Q T S + P + ++ T T P +
Sbjct: 2008 HVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTV-PPPTTLKATGSTHTAPPMTV 2066
Query: 1426 QSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSP 1470
+ G +Q S+F T++ S S +S+ SS P SP
Sbjct: 2067 TTSGTSQTHSSFSTATASSSFIS-----SSSWLPQNSSSRPPSSP 2106
Score = 34.3 bits (77), Expect = 1.2
Identities = 95/479 (19%), Positives = 160/479 (33%), Gaps = 65/479 (13%)
Query: 1062 GLQTPRISPSTHEP-----LEMTSSKSVS----PGRKGQLNDSASTPPKPSFLGVNESPS 1112
G+ P + P+T +P L T S+ G + +ST P PS SP+
Sbjct: 1191 GVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPT 1250
Query: 1113 SQ--VSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKH 1170
+ ++ +SS P S P +A + LP LR ++T P
Sbjct: 1251 QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLP--------PTATLRSTATKPTVT 1302
Query: 1171 EKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGE-RNVTLPDSQAQGSLADGLPLETAL 1229
+ + AS +S A + ++ ++ A + TLP S Q L +T
Sbjct: 1303 QATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQ-ELPGTTATQTTG 1361
Query: 1230 QEPLESSI-------PGSDGRDGVDNRSMRRSLSS-------SKPHLKPALGM----NGA 1271
P +S PG R + R+ + H P G G
Sbjct: 1362 PRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGP 1421
Query: 1272 KARSHSFSTHSGDKPSTPPIEGSGKV---RTQIITNTAERGNSLTRQNSSTESSPNKAPS 1328
+ +T + PS P V T ++T + + T +T +S + AP+
Sbjct: 1422 VTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPT 1481
Query: 1329 A--PMLESLPSVGRPSGHPSSGKGSLGSSGSFSS-----------QHGSPSKLPLRIPPK 1375
P +L + G P + G+S + SS H S + P + P
Sbjct: 1482 GTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHP-EVTPT 1540
Query: 1376 SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPS 1435
S + P T+ P A+ + R PP T P SP + P
Sbjct: 1541 STTTITP-----NPTSTRTRTPVAHT----NSATSSRPPPPFTTHSPPTGSSPFSSTGPM 1591
Query: 1436 TFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPT 1494
T + T+ + HP + S + ++P+ + + + + PT
Sbjct: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT 1650
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 58.9 bits (141), Expect = 5e-08
Identities = 102/407 (25%), Positives = 140/407 (34%), Gaps = 64/407 (15%)
Query: 783 QSNSRSSAPMGIYQKQNLTK-IPPRG----KSSPQKSKLMEPEATTLLPSSGLVTLEKSP 837
+S R+ +P Y Q+ T +PP+G +SP K++ +PE T L S G
Sbjct: 572 RSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLT 631
Query: 838 AL-------APGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKS 890
+L AP S G F + P +P + P R P+ +
Sbjct: 632 SLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPA 691
Query: 891 QTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPA 950
PG S P T P PP PP PSY + P
Sbjct: 692 VVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPP---------PSY-HPPP 741
Query: 951 PSSTKSETRV----PSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAF---KKP 1003
P + K E V SETA P + P P + P AF P
Sbjct: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSM-ADFPPPEEAFFSVASP 800
Query: 1004 IFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPP-KVSPKRGVPKTSPRQTL-------- 1054
P SPE V PA A SSS T + + PP P P +P +
Sbjct: 801 EPAGPSGSPELV---SSPA-ASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLP 856
Query: 1055 -----------GTPQRDIGLQTPRISPSTHEPLEMTSSKSV-SPGRKGQLNDSASTPPKP 1102
G P+ D+G P ++PS L+M +SV +PG S P KP
Sbjct: 857 QKEPVGCSKGGGPPREDVG--APLVTPSL---LQMVRLRSVGAPGGAPTPALGPSAPQKP 911
Query: 1103 SFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVG 1149
+ + S + S + SS + C A +GL + P G
Sbjct: 912 ----LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG 954
Score = 45.4 bits (106), Expect = 5e-04
Identities = 90/397 (22%), Positives = 133/397 (33%), Gaps = 93/397 (23%)
Query: 802 KIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGP-----L 856
K+P P K + P A L +PA+ PG +S + S P L
Sbjct: 665 KVPAPFSPPPSKPRSPNPAAPALA----------APAVVPGPVSTTDASPQSPPTPQTTL 714
Query: 857 FELRSDPHIPKHSAQLP------HSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPP 910
L+ P I K + P H P+++ V + P + + PP
Sbjct: 715 TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP 774
Query: 911 TRDEHCGSG------PEAGVKSPSPPPPPGRSVS--LLARP----------------SYD 946
E PE S + P P G S S L++ P S D
Sbjct: 775 PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPD 834
Query: 947 YSPAPSSTKSETRVPSETARTPFKSPL---------LKGISAPVISSN------------ 985
PAP + + P A+ P K P+ + + AP+++ +
Sbjct: 835 PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGA 894
Query: 986 PATTEVQRKKPSVAFKKPI------FTHPMPSPE-----AVIQTRCPAHAPSSSFTVMAL 1034
P PS A +KP+ P+P+P AV C A +
Sbjct: 895 PGGAPTPALGPS-APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN 953
Query: 1035 GPPKVSPKRGVPKTSPRQT----LGTPQRDIGLQTPRISPSTHEPLE---MTSSKSVSPG 1087
GPP+ P+ P SP T R + L+ P +SP T L+ + +S+S
Sbjct: 954 GPPEAEPR---PPQSPASTASFIFSKGSRKLQLERP-VSPETQADLQRNLVAELRSISEQ 1009
Query: 1088 RKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSP 1124
R Q + P P V PS V +S S P
Sbjct: 1010 RPPQAPKKSPKAPPP----VARKPSVGVPPPASPSYP 1042
Score = 43.9 bits (102), Expect = 0.002
Identities = 67/277 (24%), Positives = 99/277 (35%), Gaps = 47/277 (16%)
Query: 1252 RRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNS 1311
R SL S+ P +LG + + S H T S + + +G S
Sbjct: 379 RCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGS 438
Query: 1312 LTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKG-------SLGSSGSFSSQHGS 1364
+ SST S+ P P G G PS G S+ SSG S + S
Sbjct: 439 EGQPESSTASNSVVPP--------PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS 490
Query: 1365 PSKLPLRIPPK-------SEGLLIPPG------KEDQQAFTQGECPSANVAVLGEPGSDR 1411
KL PP GL +P G K +++ Q P G G+
Sbjct: 491 LRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG---GSEGAGA 547
Query: 1412 RSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPT 1471
CPP P + SPG ++ P R P+ + + + SS++ +PT
Sbjct: 548 APCPPNPANSWVPGLSPGGSRRPP--------------RSPERTLSPSSGYSSQSG-TPT 592
Query: 1472 IEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFAS 1508
+ K + + K Q KP V + + PG S +S
Sbjct: 593 LPPKGLAGPPASPGKAQ-PPKPERVTSLRSPGASVSS 628
Score = 38.1 bits (87), Expect = 0.083
Identities = 56/212 (26%), Positives = 73/212 (34%), Gaps = 64/212 (30%)
Query: 925 KSPSPPPPPGRSVSLLARP-SYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVIS 983
K PPPPP R+ SL R + P K E + + R P +G A
Sbjct: 493 KLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS-EGAGAAPCP 551
Query: 984 SNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKR 1043
NPA + V P + + P SPE + +PSS + S +
Sbjct: 552 PNPANSWVPGLSPGGSRRPP------RSPERTL-------SPSSGY----------SSQS 588
Query: 1044 GVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPS 1103
G P P+ G P SPG+ + PPKP
Sbjct: 589 GTPTLPPKGLAGPP--------------------------ASPGK--------AQPPKPE 614
Query: 1104 FLGVNESPSSQVSSS-----SSSSSPAKSHNS 1130
+ SP + VSSS SSSS PA S S
Sbjct: 615 RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS 646
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,451,622
Number of Sequences: 37866
Number of extensions: 4650373
Number of successful extensions: 32110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 1830
Number of HSP's that attempted gapping in prelim test: 21626
Number of HSP's gapped (non-prelim): 9381
length of query: 1909
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1792
effective length of database: 13,817,196
effective search space: 24760415232
effective search space used: 24760415232
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.