Search of human proteins with 42516572

Search of human proteins with 42516572

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42516572 tripartite motif-containing 41 isoform 1 [Homo
sapiens]
         (630 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]  1295   0.0  
gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]  1006   0.0  
gi|14249412 tripartite motif-containing 52 [Homo sapiens]             344   1e-94
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   290   4e-78
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   277   2e-74
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             268   1e-71
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    266   6e-71
gi|5730009 ret finger protein [Homo sapiens]                          259   7e-69
gi|37622899 ring finger protein 137 [Homo sapiens]                    226   4e-59
gi|22749269 ring finger protein 129 [Homo sapiens]                    223   4e-58
gi|15208660 tripartite motif protein 21 [Homo sapiens]                222   7e-58
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            218   1e-56
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   214   3e-55
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   214   3e-55
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    214   3e-55
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            214   3e-55
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   205   9e-53
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              205   1e-52
gi|149193331 tripartite motif protein 15 [Homo sapiens]               199   6e-51
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    198   1e-50
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    198   1e-50
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              182   6e-46
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]    181   2e-45
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]    178   1e-44
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]    178   1e-44
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]    178   1e-44
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   176   6e-44
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   174   2e-43
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      170   3e-42
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      170   3e-42

>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score = 1295 bits (3352), Expect = 0.0
 Identities = 630/630 (100%), Positives = 630/630 (100%)

Query: 1   MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60
           MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD
Sbjct: 1   MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60

Query: 61  REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120
           REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM
Sbjct: 61  REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120

Query: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180
           DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC
Sbjct: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV
Sbjct: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT
Sbjct: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL
Sbjct: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
           SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK
Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480
           MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG
Sbjct: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480

Query: 481 FRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLP 540
           FRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLP
Sbjct: 481 FRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLP 540

Query: 541 QQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAH 600
           QQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAH
Sbjct: 541 QQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAH 600

Query: 601 VHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
           VHTFSAAFLGERVFPFFRVLSKGTRIKLCP
Sbjct: 601 VHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630


>gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]
          Length = 518

 Score = 1006 bits (2601), Expect = 0.0
 Identities = 489/489 (100%), Positives = 489/489 (100%)

Query: 1   MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60
           MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD
Sbjct: 1   MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60

Query: 61  REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120
           REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM
Sbjct: 61  REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120

Query: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180
           DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC
Sbjct: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV
Sbjct: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT
Sbjct: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL
Sbjct: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
           SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK
Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480
           MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG
Sbjct: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480

Query: 481 FRSGRHYWE 489
           FRSGRHYWE
Sbjct: 481 FRSGRHYWE 489


>gi|14249412 tripartite motif-containing 52 [Homo sapiens]
          Length = 297

 Score =  344 bits (883), Expect = 1e-94
 Identities = 178/277 (64%), Positives = 213/277 (76%), Gaps = 12/277 (4%)

Query: 1   MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60
           MA  A TP+P+QTLQEEAVCAICLDYF DPVSI CGHNFCR CVTQLW  EDEED++E  
Sbjct: 1   MAGYATTPSPMQTLQEEAVCAICLDYFKDPVSISCGHNFCRGCVTQLWSKEDEEDQNE-- 58

Query: 61  REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEV-EEEEEGVFWTSGMSRSSWDN 119
             EE+E  EEE+ EAVGA  GWD  +R+  Y G+ +EE+ +++++   W      ++WDN
Sbjct: 59  --EEDEWEEEEDEEAVGAMDGWDGSIREVLYRGNADEELFQDQDDDELWLGDSGITNWDN 116

Query: 120 MDYVW--EEEDEEEDLDYYLGDMEEEDLRGEDEEDEE--EVLEEVEEEDLDP-VTPLPPP 174
           +DY+W  EEE+EEED DYYLG +   DLR +   +EE  E  +E E+E+L P + P P  
Sbjct: 117 VDYMWDEEEEEEEEDQDYYLGGLRP-DLRIDVYREEEILEAYDEDEDEELYPDIHPPPSL 175

Query: 175 PAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEAL 234
           P P + FTCPQCRKSF RRSFRPNLQLANMVQ+IRQM PTP RG+R  DQG+C KHQEAL
Sbjct: 176 PLPGQ-FTCPQCRKSFTRRSFRPNLQLANMVQIIRQMCPTPYRGNRSNDQGMCFKHQEAL 234

Query: 235 KLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYK 271
           KLFCEVD+EAICVVCRESRSHKQHSV+PLEEVVQEY+
Sbjct: 235 KLFCEVDKEAICVVCRESRSHKQHSVLPLEEVVQEYQ 271


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  290 bits (741), Expect = 4e-78
 Identities = 166/440 (37%), Positives = 247/440 (56%), Gaps = 37/440 (8%)

Query: 179 RCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFC 238
           R F CP CRK+   RS RPN QL +MV++ +Q+        ++ D+ +CP+H EAL LFC
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVK---RKIRDESLCPQHHEALSLFC 118

Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298
             D+EA+C++C  S +H+ H+VVPL++  QEYK KLQ  +EPL + L+ + + K+ EE++
Sbjct: 119 YEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKK 178

Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358
             ELK  ++S    +  EF  L R L EEQ  L  RL E  +  L R    A+ L ++  
Sbjct: 179 PGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRR 238

Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIV 418
            L+ L AE + +  Q G  +L+D+K T  +CE+V+       S +  +  S+       +
Sbjct: 239 DLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFAL 298

Query: 419 RKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERR-QEVADHPKRFSADCCVLG 477
           RK+ +        D+TLDP+TAHP L+LS DR+ V+  E R +++ D P+RF+   CVL 
Sbjct: 299 RKILKQLI----ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLA 354

Query: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
            +GF SGRHYWEVEVG +  WAVG  R+S   K ++ P                      
Sbjct: 355 TEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTP---------------------- 392

Query: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAET 597
            LP+    +  +W    NG +Y A ++T  T L    KP+R G++LDYEAG L FYN   
Sbjct: 393 -LPETGYWRVRLW----NGDKY-AATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTD 446

Query: 598 LAHVHTFSAAFLGERVFPFF 617
            +H++TF+  F  E+++P F
Sbjct: 447 RSHIYTFTDTFT-EKLWPLF 465



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 23/47 (48%), Positives = 33/47 (70%)

Query: 2  AAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          A+ A T   ++ LQ EA C++CL+Y  +PV I CGHNFC+ C+T+ W
Sbjct: 11 ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW 57


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  277 bits (709), Expect = 2e-74
 Identities = 168/470 (35%), Positives = 248/470 (52%), Gaps = 67/470 (14%)

Query: 179 RCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFC 238
           R F CP CRK+   RS RPN QL +MV++ +Q+        ++ D+ +CP+H EAL LFC
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVK---RKIRDESLCPQHHEALSLFC 118

Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298
             D+EA+C++C  S +H+ H+VVPL++  QEYK KLQ  +EPL + L+ + + K+ EE++
Sbjct: 119 YEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKK 178

Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358
             ELK  ++S    +  EF  L R L EEQ  L  RL E  +  L R    A+ L ++  
Sbjct: 179 PGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRR 238

Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETF------------------------------NR 388
            L+ L AE + +  Q G  +L+D+K T                               NR
Sbjct: 239 DLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINR 298

Query: 389 CEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSP 448
           CE+V+       S +  +  S+       +RK+ +        D+TLDP+TAHP L+LS 
Sbjct: 299 CEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI----ADVTLDPETAHPNLVLSE 354

Query: 449 DRRGVRLAERR-QEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAAREST 507
           DR+ V+  E R +++ D P+RF+   CVL  +GF SGRHYWEVEVG +  WAVG  R+S 
Sbjct: 355 DRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSV 414

Query: 508 HHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQ 567
             K ++ P                       LP+    +  +W    NG +Y A ++T  
Sbjct: 415 SRKGELTP-----------------------LPETGYWRVRLW----NGDKY-AATTTPF 446

Query: 568 TLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFF 617
           T L    KP+R G++LDYEAG L FYN    +H++TF+  F  E+++P F
Sbjct: 447 TPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFT-EKLWPLF 495



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 23/47 (48%), Positives = 33/47 (70%)

Query: 2  AAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          A+ A T   ++ LQ EA C++CL+Y  +PV I CGHNFC+ C+T+ W
Sbjct: 11 ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW 57


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  268 bits (684), Expect = 1e-71
 Identities = 166/457 (36%), Positives = 235/457 (51%), Gaps = 52/457 (11%)

Query: 177 PRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKL 236
           P   + CP+CR+  P+R+ RPN  LA M ++ R++HP          QG+CP H+E L  
Sbjct: 47  PEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSP-----VPQGVCPAHREPLAA 101

Query: 237 FCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEE 296
           FC  +   +C  C  S  H  H V PL++  ++ KAKL+  +E LRK ++     +A+ +
Sbjct: 102 FCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQAD 161

Query: 297 RRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQ 356
                 +  ++S+   V  EF RL R LAEE+  L +RL E     L R    A+ L +Q
Sbjct: 162 ETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQ 221

Query: 357 AAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFL 413
           +A L+ L+AE + R Q   L LLQDIK+   R ++V+LQPPEV   +    C+       
Sbjct: 222 SAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCR------- 274

Query: 414 TDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADC 473
              +V  + R      R D+TLDPDTA+P L+LS DRR V+  + RQ + D P+RF    
Sbjct: 275 VPGLVETLRRF-----RGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGP 329

Query: 474 CVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHR 533
           CVLG + F SGRHYWEVEVG R  WA+G  RE+ + KEK   G  S G+G          
Sbjct: 330 CVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEK---GELSAGNG---------- 376

Query: 534 RRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFY 593
                           W +   G  Y   +S+E+ L    + PRR G++LDYEAG L FY
Sbjct: 377 ---------------FWILVFLGSYY---NSSERALAPLRDPPRRVGIFLDYEAGHLSFY 418

Query: 594 NAETLAHVHTFSAAFLGERVFPFFRVLSKG-TRIKLC 629
           +A   + +  F        + P F  LS   T + +C
Sbjct: 419 SATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTIC 455



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 28/42 (66%), Positives = 31/42 (73%)

Query: 8  PNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49
          P+    LQEEA CAICLDYFTDPV   CGHNFCR C+ + WG
Sbjct: 4  PDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWG 45


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  266 bits (679), Expect = 6e-71
 Identities = 174/478 (36%), Positives = 245/478 (51%), Gaps = 51/478 (10%)

Query: 169 TPLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMH---PTPGR-GSRVTDQ 224
           T  PP P P     CPQCR+       RPN QLA +  ++R+       PG  GS+    
Sbjct: 69  TRAPPFPLP-----CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAA 123

Query: 225 GI----CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEP 280
                 C +H E  KL+C+ D  AICVVC  +R H++H+V+PL+E VQE K  L+  +  
Sbjct: 124 RAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRV 183

Query: 281 LRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHE 340
           L+K LE  +  ++ E++   EL  QM +E   V +EF  L  FL E++  L  RL E+  
Sbjct: 184 LKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSR 243

Query: 341 AQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVW 400
               +     ++L  +  QLS+L ++ QE +Q+  L  LQ+ K T +RC  V    P   
Sbjct: 244 EVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTV 303

Query: 401 SPDPCQPHSHDFLTDAIVRKMSRMFCQAAR--------VDLTLDPDTAHPALMLSPDRRG 452
           S +      +  L   +++ M + F +  R        V+LTLDPDTA+P L+LS D +G
Sbjct: 304 SSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKG 363

Query: 453 VRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEK 512
           VRL ER Q++ +HP RF  +  VL + GF SGRH+WEVEVG + GWA G ARES      
Sbjct: 364 VRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV----- 418

Query: 513 VGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSP 572
                                RR+   P  P  +  VW +  NG +Y A +S E++ LS 
Sbjct: 419 ---------------------RRKGLTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSC 455

Query: 573 SEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
               R   V LD E G + FY  E + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 456 GHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 511



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 20/35 (57%), Positives = 27/35 (77%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          LQ EA C+ICL+ F +PVS+ CGH+FCR C+ + W
Sbjct: 23 LQGEATCSICLELFREPVSVECGHSFCRACIGRCW 57


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  259 bits (661), Expect = 7e-69
 Identities = 163/471 (34%), Positives = 248/471 (52%), Gaps = 53/471 (11%)

Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
           +CPQCR++FP+R  RPN  LAN+ Q+++Q+      G    + G+C KH+E LKL+CE D
Sbjct: 52  SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPG-GEMGVCEKHREPLKLYCEED 110

Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
           +  ICVVC  SR H+ HSV+PLEE V+ +K ++Q  ++ L++  +  ++ +A+ E+   E
Sbjct: 111 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE 170

Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
           L S  + E   +  EF +L   L E +  L  RL E+  A       A ++ +   + LS
Sbjct: 171 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS 230

Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHD------FLTD 415
            L+A+ +E+ QQ    LLQDI +T +R E +++  P +  PD  Q   H       FLT+
Sbjct: 231 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPD-LQEKIHIFAQKCLFLTE 289

Query: 416 AIVRKMSRM-----------FCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464
           ++ +   +M             Q   VD+TLDPDTA+P+L+LS + R VR +  +Q++ D
Sbjct: 290 SLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPD 349

Query: 465 HPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGD 524
           +P+RF+   CVLG+  F +GRHYWEVEVG +  W +G   +S   K            G 
Sbjct: 350 NPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRK------------GG 397

Query: 525 ASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKP-RRFGVYL 583
            +S+           PQ       +W     GK Y A +S    L  P   P +R G++L
Sbjct: 398 VTSA-----------PQNGFWAVSLW----YGKEYWALTSPMTAL--PLRTPLQRVGIFL 440

Query: 584 DYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTR----IKLCP 630
           DY+AG + FYN     H  TFS A     V P+F +   G +    + +CP
Sbjct: 441 DYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICP 491



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 17/38 (44%), Positives = 25/38 (65%)

Query: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49
          + LQ+E  C +CL YF +P+ + CGHN C  C+ + WG
Sbjct: 8  ECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWG 45


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  226 bits (577), Expect = 4e-59
 Identities = 153/454 (33%), Positives = 227/454 (50%), Gaps = 63/454 (13%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           +TCP CR     R+ RPN QLAN+V+ +R +   PG G +     +C +H E LK+FC+ 
Sbjct: 55  YTCPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLK---GDLCERHGEKLKMFCKE 111

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D   +C  C +S  H+ HSVVP+E+V  EYK +L   +E L+K  E   K++  E +R  
Sbjct: 112 DVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTA 171

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQ--------------AGLERRLRE-MHEAQLGR 345
             K Q+++   ++  EF +  R L ++Q              A L+R   E M + +L  
Sbjct: 172 TWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNH 231

Query: 346 AGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPC 405
                S L +Q+  L R++AE +ERSQ+    +LQDI+E  NR +   LQ PE       
Sbjct: 232 -----SELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPE------- 279

Query: 406 QPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADH 465
            P S +  TD  V  + R   +    D+ LDPDTA+  L++S DR+ V   +  Q++ D+
Sbjct: 280 -PISLELKTDCRVLGL-REILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDN 337

Query: 466 PKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDA 525
           P+RF     VLG+Q   SGRHYWEVEVG R  W +G  +++   KE V            
Sbjct: 338 PERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVV------------ 385

Query: 526 SSSRHHHRRRRLHLPQQPLLQREVWCVG-TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLD 584
             S H+                  W +    G  Y+A  + E  +LS    PRR G+++D
Sbjct: 386 YLSPHY----------------GFWVIRLRKGNEYRA-GTDEYPILSLPVPPRRVGIFVD 428

Query: 585 YEAGRLGFYN-AETLAHVHTFSAAFLGERVFPFF 617
           YEA  + FYN  +  +H+ TF       R+ P+F
Sbjct: 429 YEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYF 462



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 17/38 (44%), Positives = 26/38 (68%)

Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          V+ + EE  C IC+ +  +P+SI CGH+FC  C++ LW
Sbjct: 7  VEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLW 44


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  223 bits (568), Expect = 4e-58
 Identities = 134/449 (29%), Positives = 222/449 (49%), Gaps = 35/449 (7%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           F CP CR  FP +SFR N QL N+ ++ +Q+     +  R  +  +C KH + L LFC  
Sbjct: 51  FPCPVCRFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVK 110

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D E +C  C  S  H++H + P+++    ++  L+G +EPLR ++E V+K+   +  +  
Sbjct: 111 DLEILCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSV 170

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           ELK +++ +   + SEF ++  FL  EQ  + R++++     L +       L++  + L
Sbjct: 171 ELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTL 230

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
             LL E + +S Q  L LL   K   ++ +   L+ PE++S    +   + F        
Sbjct: 231 KHLLREVEGKSVQSNLELLTQAKSMHHKYQ--NLKCPELFS---FRLTKYGFSLPPQYSG 285

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480
           + R+  +  +VD+ LD +TAHP L++S DR+ VR   +++ +   P+RF     VLG+Q 
Sbjct: 286 LDRII-KPFQVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQR 344

Query: 481 FRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLP 540
           F SGRHYWEVEVG +  W +G  ++                                +  
Sbjct: 345 FSSGRHYWEVEVGNKPKWILGVCQDCLLR----------------------------NWQ 376

Query: 541 QQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAH 600
            QP +    W +G   K     S  + T L P  KP + G++LDYE G L FYN    + 
Sbjct: 377 DQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSI 436

Query: 601 VHTFSAAFLGERVFPFFRVLSKGTRIKLC 629
           ++TF+  F  E V+P+F   +    +K+C
Sbjct: 437 LYTFNDCFT-EAVWPYFYTGTDSEPLKIC 464



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 23/40 (57%), Positives = 29/40 (72%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDE 53
          LQEE+ C ICL+Y  DPV+I CGHNFCR C++  W   D+
Sbjct: 10 LQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDD 49


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  222 bits (566), Expect = 7e-58
 Identities = 143/436 (32%), Positives = 219/436 (50%), Gaps = 41/436 (9%)

Query: 183 CPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVDE 242
           CP CR+ F  ++ RPN QLANMV  ++++      G   T    C  H E L LFCE D 
Sbjct: 51  CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREG---TQGERCAVHGERLHLFCEKDG 107

Query: 243 EAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTEL 302
           +A+C VC +SR H+ H++VPLEE  QEY+ KLQ  +  LR+  E  +K++ +   +  + 
Sbjct: 108 KALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADW 167

Query: 303 KSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSR 362
           K  ++++ + + +EF +   FL EE+    + L +    QL   G   ++LA+Q+  L  
Sbjct: 168 KKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQE 227

Query: 363 LLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMS 422
           L++E   R     L LLQ++     R E   L+  ++ SP        +  +   V  + 
Sbjct: 228 LISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSP--------ELRSVCHVPGLK 279

Query: 423 RMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQGFR 482
           +M  +   V +TLDPDTA+P L+LS DRR VRL + +Q +  + +RF +   VLGAQ F 
Sbjct: 280 KML-RTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFH 338

Query: 483 SGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLPQQ 542
           SG+HYWEV+V G+  W +G  R+S   K   G    S  SG                   
Sbjct: 339 SGKHYWEVDVTGKEAWDLGVCRDSVRRK---GHFLLSSKSG------------------- 376

Query: 543 PLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN-AETLAHV 601
                  W +    K+     +  QT L     P + G++LDYEAG + FYN  +  + +
Sbjct: 377 ------FWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLI 430

Query: 602 HTFSAAFLGERVFPFF 617
           ++FS       + PFF
Sbjct: 431 YSFSECAFTGPLRPFF 446



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 20/35 (57%), Positives = 26/35 (74%)

Query: 16 EEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGG 50
          EE  C ICLD F +PVSI CGH+FC+ C++Q+  G
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG 46


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  218 bits (556), Expect = 1e-56
 Identities = 142/432 (32%), Positives = 208/432 (48%), Gaps = 46/432 (10%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           + CPQCR  F    FRPN QLA +V+ +R++    G G+R      C +H E L  FCE 
Sbjct: 55  YACPQCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARR-----CARHGEDLSRFCEE 109

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           DE A+C VC     H+ H   PL+E    Y+ KLQ  +E +RK LE     +A   ++  
Sbjct: 110 DEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTV 169

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
             K +++ +      EF +   FLA+E+    RRL     A L R   + SRL +Q+  L
Sbjct: 170 IWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKAL 229

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEV-QLQPPEVWSPDPCQPHSHDFLTDAIVR 419
             L  E QER Q+  L LL+ ++   +R + V +L+   +    P +      L  A   
Sbjct: 230 KELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENI----PME------LKTACCI 279

Query: 420 KMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQ 479
              R   +  +VD+ LDP TAHP+L+L+ D R V+  E  ++V ++P+RF    C+LG Q
Sbjct: 280 PGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQ 339

Query: 480 GFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHL 539
            F SGRHYWEV VG    W +G  +++   K +  P                        
Sbjct: 340 SFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSP---------------------- 377

Query: 540 PQQPLLQREVWCVG-TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETL 598
                 +  VW +    G  Y   +S    LL   E PR  G++LDYEAG + FYN    
Sbjct: 378 ------ENGVWALWLLKGNEYMVLASPSVPLLQ-LESPRCIGIFLDYEAGEISFYNVTDG 430

Query: 599 AHVHTFSAAFLG 610
           ++++TF+  F G
Sbjct: 431 SYIYTFNQLFSG 442



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 14/112 (12%)

Query: 10  PVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEED-------------R 56
           P + L+E+A C +CLD+  +PVS+ CGH+FC  C+++     D                R
Sbjct: 6   PGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFR 65

Query: 57  DELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFW 108
               R   +  G  E V  +G GAG     R   +  D+    EE+E  + W
Sbjct: 66  PSGFRPNRQLAGLVESVRRLGLGAG-PGARRCARHGEDLSRFCEEDEAALCW 116


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  214 bits (544), Expect = 3e-55
 Identities = 144/441 (32%), Positives = 220/441 (49%), Gaps = 48/441 (10%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           F CP+CR+  P+R+  PN  L  + ++ +Q HP       +  Q +C +H E LKLFC+ 
Sbjct: 33  FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 85

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D+  ICVVCRESR H+ H V+P EE VQ YK KL+  +E LR+ +     ++A+EE+ + 
Sbjct: 86  DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 145

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           E + ++K     +  EF ++  +L EE+  L + L    E    R   + + L  Q   L
Sbjct: 146 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 205

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
             LL + +ERS QG L++LQD+KE  +R   V +Q PEV    P +P +   +   I  +
Sbjct: 206 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 261

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479
           + R F +    D+  D  +A+P L+L   R+   L    +      K RF A  C +G  
Sbjct: 262 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 317

Query: 480 GFRSGRHYWEV--EVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
            F SGRHYWEV   + G   WA+G  R++   K++V                        
Sbjct: 318 AFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRV------------------------ 353

Query: 538 HLPQQPLLQREVWCVG-TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596
             P+ P  +   W V  + G +Y +  S   T +   E P   G++LD+EAG + FY+  
Sbjct: 354 --PKCP--ENGFWVVQLSKGTKYLSTFSA-LTPVMLMEPPSHMGIFLDFEAGEVSFYSVS 408

Query: 597 TLAHVHTFSAAFLGERVFPFF 617
             +H+HT+S A     + PFF
Sbjct: 409 DGSHLHTYSQATFPGPLQPFF 429



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 9/14 (64%), Positives = 10/14 (71%)

Query: 35 CGHNFCRVCVTQLW 48
          CGHNFCR C+   W
Sbjct: 4  CGHNFCRACIQLSW 17


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  214 bits (544), Expect = 3e-55
 Identities = 144/441 (32%), Positives = 220/441 (49%), Gaps = 48/441 (10%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           F CP+CR+  P+R+  PN  L  + ++ +Q HP       +  Q +C +H E LKLFC+ 
Sbjct: 60  FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 112

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D+  ICVVCRESR H+ H V+P EE VQ YK KL+  +E LR+ +     ++A+EE+ + 
Sbjct: 113 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 172

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           E + ++K     +  EF ++  +L EE+  L + L    E    R   + + L  Q   L
Sbjct: 173 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 232

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
             LL + +ERS QG L++LQD+KE  +R   V +Q PEV    P +P +   +   I  +
Sbjct: 233 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 288

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479
           + R F +    D+  D  +A+P L+L   R+   L    +      K RF A  C +G  
Sbjct: 289 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 344

Query: 480 GFRSGRHYWEV--EVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
            F SGRHYWEV   + G   WA+G  R++   K++V                        
Sbjct: 345 AFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRV------------------------ 380

Query: 538 HLPQQPLLQREVWCVG-TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596
             P+ P  +   W V  + G +Y +  S   T +   E P   G++LD+EAG + FY+  
Sbjct: 381 --PKCP--ENGFWVVQLSKGTKYLSTFSA-LTPVMLMEPPSHMGIFLDFEAGEVSFYSVS 435

Query: 597 TLAHVHTFSAAFLGERVFPFF 617
             +H+HT+S A     + PFF
Sbjct: 436 DGSHLHTYSQATFPGPLQPFF 456



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 25/35 (71%), Positives = 27/35 (77%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          LQEEA C+ICLDYFTDPV   CGHNFCR C+   W
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW 44


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  214 bits (544), Expect = 3e-55
 Identities = 144/441 (32%), Positives = 220/441 (49%), Gaps = 48/441 (10%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           F CP+CR+  P+R+  PN  L  + ++ +Q HP       +  Q +C +H E LKLFC+ 
Sbjct: 60  FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 112

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D+  ICVVCRESR H+ H V+P EE VQ YK KL+  +E LR+ +     ++A+EE+ + 
Sbjct: 113 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 172

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           E + ++K     +  EF ++  +L EE+  L + L    E    R   + + L  Q   L
Sbjct: 173 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 232

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420
             LL + +ERS QG L++LQD+KE  +R   V +Q PEV    P +P +   +   I  +
Sbjct: 233 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 288

Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479
           + R F +    D+  D  +A+P L+L   R+   L    +      K RF A  C +G  
Sbjct: 289 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 344

Query: 480 GFRSGRHYWEV--EVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
            F SGRHYWEV   + G   WA+G  R++   K++V                        
Sbjct: 345 AFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRV------------------------ 380

Query: 538 HLPQQPLLQREVWCVG-TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596
             P+ P  +   W V  + G +Y +  S   T +   E P   G++LD+EAG + FY+  
Sbjct: 381 --PKCP--ENGFWVVQLSKGTKYLSTFSA-LTPVMLMEPPSHMGIFLDFEAGEVSFYSVS 435

Query: 597 TLAHVHTFSAAFLGERVFPFF 617
             +H+HT+S A     + PFF
Sbjct: 436 DGSHLHTYSQATFPGPLQPFF 456



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 25/35 (71%), Positives = 27/35 (77%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          LQEEA C+ICLDYFTDPV   CGHNFCR C+   W
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW 44


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  214 bits (544), Expect = 3e-55
 Identities = 129/453 (28%), Positives = 214/453 (47%), Gaps = 45/453 (9%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240
           F CP CR       FR N QL  M+++ + +  T     +  +  +C KH + L +FC+ 
Sbjct: 51  FPCPVCRHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKE 110

Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300
           D   +C +C +   H+ H V P+E+    Y+ +   +++PL+K L  +QK+ + + ++  
Sbjct: 111 DLMVLCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPL 170

Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360
           EL+  ++++   ++SEF  L +FL  EQ  +  RL E  +    +  A  +  +  +A L
Sbjct: 171 ELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATL 230

Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWS----PDPCQPHSHDFLTDA 416
              L++  E S+   L LL  IK  +   E      P ++S     D C           
Sbjct: 231 KSQLSKVVELSELSELELLSQIKIFY---ESENESSPSIFSIHLKRDGCSFPPQYSALQR 287

Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476
           I++K         +V++ LDP+TAHP L++S D++ VR  +R+Q+V   PKRF+    VL
Sbjct: 288 IIKKF--------KVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVL 339

Query: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536
           G   F SGRH+WE+EVG +  WA+G  ++S   K +                        
Sbjct: 340 GFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKAR------------------------ 375

Query: 537 LHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596
               +    Q+E W +      Y A  +    LL    K R  G++LDYE G + FYN  
Sbjct: 376 ----RPSSAQQECWRIELQDDGYHAPGAFPTPLLL-EVKARAIGIFLDYEMGEISFYNMA 430

Query: 597 TLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLC 629
             +H+ TF+  F G  + P+F V      +++C
Sbjct: 431 EKSHICTFTDTFTGP-LRPYFYVGPDSQPLRIC 462



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 24/35 (68%), Positives = 28/35 (80%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          LQ EA C+ICLDY +DPV+I CGHNFCR C+ Q W
Sbjct: 10 LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSW 44


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  205 bits (522), Expect = 9e-53
 Identities = 144/464 (31%), Positives = 228/464 (49%), Gaps = 39/464 (8%)

Query: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232
           P P      TCP C++ F   SFRPN QLAN+V+ I ++      G  + ++ +C +H E
Sbjct: 47  PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104

Query: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292
            +  FCE DE  +CVVCRE+  H  H++  LE+    Y+ ++   ++ LRK  E +Q+++
Sbjct: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164

Query: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352
           ++E +R+  L +Q+ ++   V SEF  L +FL E+Q+ L  +L       L +       
Sbjct: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224

Query: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412
           +A +  + S L+ E +E++++    LL DI+ T  RCE  + + P   SP+  Q    DF
Sbjct: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283

Query: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464
              A+ +++  +MF +    +L       +LDP T+HP L+LS D +  + + + Q   D
Sbjct: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343

Query: 465 HPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGD 524
           +P+RF    CVL   G   GRH W V +    G                  G  +VG   
Sbjct: 344 NPQRFDRATCVLAHTGITGGRHTWVVSIDLAHG------------------GSCTVGVVS 385

Query: 525 ASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLD 584
               R    R R   P++      VW V        A  S   T L+  E+PR+  V LD
Sbjct: 386 EDVQRKGELRLR---PEEG-----VWAVRLAWGFVSALGSFP-TRLTLKEQPRQVRVSLD 436

Query: 585 YEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628
           YE G + F NA T   ++TF+A+F   +V PFF +  +G+   L
Sbjct: 437 YEVGWVTFTNAVTREPIYTFTASFT-RKVIPFFGLWGRGSSFSL 479



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 18/36 (50%), Positives = 24/36 (66%)

Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46
          V +L +E  C IC     +PV+I CGHNFCR C+T+
Sbjct: 7  VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  205 bits (521), Expect = 1e-52
 Identities = 140/443 (31%), Positives = 215/443 (48%), Gaps = 51/443 (11%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGI-CPKHQEALKLFCE 239
           F CPQCR  F   S RPN QL ++++ +++           TDQ + C +H E   LFCE
Sbjct: 57  FCCPQCRAPFHMDSLRPNKQLGSLIEALKE-----------TDQEMSCEEHGEQFHLFCE 105

Query: 240 VDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRV 299
            + + IC  C  +  HK H+   +E+V Q YK KLQ  V  L++  +   + K     R+
Sbjct: 106 DEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRI 165

Query: 300 TELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQ 359
           T+ K +++ +   + S+F  L  FL EE+     RL +  +  L R     + L  ++ +
Sbjct: 166 TKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNE 225

Query: 360 LSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFLTDA 416
           L   + E +E+ Q    +LLQ++ +T +R   V+L+  E  S +    C      F    
Sbjct: 226 LKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYF---- 281

Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476
            V+KM R    + +V +TLDPDTAH  L+LS DRR V     ++      +RF+A  CVL
Sbjct: 282 DVKKMLR----SHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVL 337

Query: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536
           G +GF SGR Y+EV+VG   GW +G   E+              G+G             
Sbjct: 338 GCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQR-----------GTG------------- 373

Query: 537 LHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596
             + Q+P  Q   W +    K+     ++  T L   E+P   G++LDYEAG + FYN  
Sbjct: 374 --MKQEP--QSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGN 429

Query: 597 TLAHVHTFSAAFLGERVFPFFRV 619
           T  H+ TF  A   + + P+F+V
Sbjct: 430 TGCHIFTFPKASFSDTLRPYFQV 452



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 18/35 (51%), Positives = 26/35 (74%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          + EEA C+ICL   T+PVSI CGH++C +C+T  +
Sbjct: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFF 44


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  199 bits (506), Expect = 6e-51
 Identities = 134/411 (32%), Positives = 208/411 (50%), Gaps = 39/411 (9%)

Query: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286
           C +H E +  FCE D E +CV CRE  +H+ H+V  L+E +Q Y+ +L+  +E L    +
Sbjct: 83  CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERD 142

Query: 287 AVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRA 346
            ++ +K +E++++  L +Q++S+   V + F RL + L +++  L  RLRE+ +      
Sbjct: 143 EIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKER 202

Query: 347 GAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQ 406
               ++++E+  +L   + E +E+ QQ    LLQD++   +RCE      PE  SPD  +
Sbjct: 203 DEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVK 262

Query: 407 P----HSHDFLTDAIVRKMSRMFCQAARVD---LTLDPDTAHPALMLSPDRRGVRLAERR 459
                H        ++R  S        +D   +TLDP TA  +L+LS DR+ VR   ++
Sbjct: 263 KIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQK 322

Query: 460 QEVADHPKRFSADCCVLGAQGFRSGRHYWEVEV--GGRRGWAVGAARESTHHKEKVGPGG 517
           + + D P RF     VLG  GF SGRH W+V++  G   G  VG A E    K   G  G
Sbjct: 323 KSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRK---GEMG 379

Query: 518 SSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPR 577
            S   G                         VW V  + ++  A S++  T L  SE PR
Sbjct: 380 LSAEDG-------------------------VWAVIISHQQCWA-STSPGTDLPLSEIPR 413

Query: 578 RFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628
              V LDYEAG++  +NA+T   + TF+A+F G +VFPFF V  KG+ + L
Sbjct: 414 GVRVALDYEAGQVTLHNAQTQEPIFTFTASFSG-KVFPFFAVWKKGSCLTL 463



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 7  TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47
          TP+ ++ + E   C +C     D V+I CGH FCR+C+  L
Sbjct: 4  TPS-LKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPAL 43


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  198 bits (504), Expect = 1e-50
 Identities = 136/444 (30%), Positives = 217/444 (48%), Gaps = 34/444 (7%)

Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
           +CP C+ S+   + RPN  LAN+V+ +R++   PG+  +     +C  H E L+LFC+ D
Sbjct: 55  SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 111

Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
            + IC +C  S+ H+ H    +EEV QEY+ K Q  ++ L+   +  +K+ A    + T 
Sbjct: 112 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 171

Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
            K+QM+ E   + +EF +L   L   +    ++L +  +  L     A + L  Q   L 
Sbjct: 172 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 231

Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421
            L+++ + R Q   + LLQD+ +   R E   L+ PE     P +  S     D  +++M
Sbjct: 232 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 286

Query: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476
            R+       Q+  VD+TL+P TA+  L+L+ +RR VR    +       ++   DC VL
Sbjct: 287 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 345

Query: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536
           G+Q F SG+HYWEV+V  +  W +G    S                G   S  H  +   
Sbjct: 346 GSQHFSSGKHYWEVDVAKKTAWILGVCSNSL---------------GPTFSFNHFAQNHS 390

Query: 537 LHLPQQPLLQREVWCVG-TNGKRYQA-QSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594
            +   QP  Q   W +G  +   Y+A + S+   LLS +  PRR GV+LDYEAG + FYN
Sbjct: 391 AYSRYQP--QSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYN 448

Query: 595 AETLAH-VHTFSAAFLGERVFPFF 617
                  ++TFS  +    + P+F
Sbjct: 449 VTNHGFPIYTFSKYYFPTTLCPYF 472



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 19/40 (47%), Positives = 28/40 (70%)

Query: 6  MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45
          MT   +  ++EE  C ICL+  T+P+SI CGH+FC+ C+T
Sbjct: 1  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 40


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  198 bits (504), Expect = 1e-50
 Identities = 136/444 (30%), Positives = 217/444 (48%), Gaps = 34/444 (7%)

Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
           +CP C+ S+   + RPN  LAN+V+ +R++   PG+  +     +C  H E L+LFC+ D
Sbjct: 83  SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 139

Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
            + IC +C  S+ H+ H    +EEV QEY+ K Q  ++ L+   +  +K+ A    + T 
Sbjct: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199

Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
            K+QM+ E   + +EF +L   L   +    ++L +  +  L     A + L  Q   L 
Sbjct: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259

Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421
            L+++ + R Q   + LLQD+ +   R E   L+ PE     P +  S     D  +++M
Sbjct: 260 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 314

Query: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476
            R+       Q+  VD+TL+P TA+  L+L+ +RR VR    +       ++   DC VL
Sbjct: 315 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 373

Query: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536
           G+Q F SG+HYWEV+V  +  W +G    S                G   S  H  +   
Sbjct: 374 GSQHFSSGKHYWEVDVAKKTAWILGVCSNSL---------------GPTFSFNHFAQNHS 418

Query: 537 LHLPQQPLLQREVWCVG-TNGKRYQA-QSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594
            +   QP  Q   W +G  +   Y+A + S+   LLS +  PRR GV+LDYEAG + FYN
Sbjct: 419 AYSRYQP--QSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYN 476

Query: 595 AETLAH-VHTFSAAFLGERVFPFF 617
                  ++TFS  +    + P+F
Sbjct: 477 VTNHGFPIYTFSKYYFPTTLCPYF 500



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 19/40 (47%), Positives = 28/40 (70%)

Query: 6  MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45
          MT   +  ++EE  C ICL+  T+P+SI CGH+FC+ C+T
Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 68


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  182 bits (463), Expect = 6e-46
 Identities = 138/497 (27%), Positives = 233/497 (46%), Gaps = 59/497 (11%)

Query: 183 CPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRG-SRVT----DQGICPKHQEALKLF 237
           CP C+K F + + RP  QLA++V+ I ++    GR    VT    D  +C +H+E L  +
Sbjct: 53  CPLCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYY 112

Query: 238 CEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEER 297
           CE D + +CV+CRESR H+ H+ V +E+  Q ++ K+  H+  LR+  + +Q  +AK E 
Sbjct: 113 CEDDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEA 172

Query: 298 RVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQA 357
            +     +++ +   + +EF +  +FL E +  L  +L ++ +          SR   + 
Sbjct: 173 DILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGEL 232

Query: 358 AQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDP----CQPHSHDFL 413
           A+L+ +++E + ++QQ    L+QD ++  NR         + W   P     +  + +F 
Sbjct: 233 ARLALVISELEGKAQQPAAELMQDTRDFLNRYPR-----KKFWVGKPIARVVKKKTGEFS 287

Query: 414 TDAI-VRKMSRMF-------CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADH 465
              + +++  R F        +   V +TLDP +A   L LS D + V      +    H
Sbjct: 288 DKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLH 347

Query: 466 PKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAAR-------ESTHHKEKVGPGG- 517
           P++F  +  VLG++GF  G+ YWEVEV  R GW+            E    +E+ G G  
Sbjct: 348 PQQFDCEPGVLGSKGFTWGKVYWEVEV-EREGWSEDEEEGDEEEEGEEEEEEEEAGYGDG 406

Query: 518 ----------SSVGSGDASSSRHHHR--------------RRRLHLPQQPLLQREVWCVG 553
                      S+G  +                       +R+  L  +P  +  VW + 
Sbjct: 407 YDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRP--EDGVWALR 464

Query: 554 TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERV 613
            +     A +S E  L  P+ +PRR G+ LDYE G + F NAE+   ++TF+A F   R+
Sbjct: 465 LSSSGIWANTSPEAELF-PALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFT-RRL 522

Query: 614 FPFFRVLSKGTRIKLCP 630
            PF  +   GTR+ L P
Sbjct: 523 VPFLWLKWPGTRLLLRP 539



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 23/41 (56%), Positives = 30/41 (73%)

Query: 7  TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47
          T  P+++L+EE  C+ICLDY  DPV+I CGH FCR C T +
Sbjct: 3  TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDV 43



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 36/70 (51%), Positives = 41/70 (58%), Gaps = 9/70 (12%)

Query: 51  EDEEDRDELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYE--GDMEEEVEEEEEGVFW 108
           EDEE+ DE     EEE  EEEE E  G G G+D    DED E  GD EEE EEEEE V  
Sbjct: 381 EDEEEGDE-----EEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLE 435

Query: 109 TS--GMSRSS 116
           +   G++R S
Sbjct: 436 SCMVGVARDS 445



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 27/87 (31%)

Query: 82  WDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLG--- 138
           W+  +  E +  D EEE +EEEEG                   EEE+EEE+  Y  G   
Sbjct: 370 WEVEVEREGWSED-EEEGDEEEEG-------------------EEEEEEEEAGYGDGYDD 409

Query: 139 ---DMEEEDLRGEDEEDEEEVLEEVEE 162
              D +EE L G++EE+EEE  EEV E
Sbjct: 410 WETDEDEESL-GDEEEEEEEEEEEVLE 435



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 20/78 (25%)

Query: 81  GWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLGDM 140
           GW     +++ EGD EEE EEEEE      G     W+       +EDEE      LGD 
Sbjct: 378 GWS----EDEEEGDEEEEGEEEEEEEEAGYGDGYDDWET------DEDEES-----LGDE 422

Query: 141 EEEDLRGEDEEDEEEVLE 158
           EEE+      E+EEEVLE
Sbjct: 423 EEEE-E----EEEEEVLE 435



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 15/84 (17%)

Query: 51  EDEEDRDEL-DREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWT 109
           E +ED + L D EEEEE+ EEE +E+   G   D+  R    +GD+       E+GV W 
Sbjct: 411 ETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKR----KGDLS---LRPEDGV-WA 462

Query: 110 SGMSRSSWDNMDYVWEEEDEEEDL 133
             +S S       +W     E +L
Sbjct: 463 LRLSSSG------IWANTSPEAEL 480


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score =  181 bits (458), Expect = 2e-45
 Identities = 121/336 (36%), Positives = 170/336 (50%), Gaps = 38/336 (11%)

Query: 303 KSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSR 362
           + QM +E   V +EF  L  FL E++  L  RL E+      +     ++L  +  QLS+
Sbjct: 24  QKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSK 83

Query: 363 LLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMS 422
           L ++ QE +Q+  L  LQ+ K T +RC  V    P   S +      +  L   +++ M 
Sbjct: 84  LSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGML 143

Query: 423 RMFCQAAR--------VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCC 474
           + F +  R        V+LTLDPDTA+P L+LS D +GVRL ER Q++ +HP RF  +  
Sbjct: 144 KKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTR 203

Query: 475 VLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRR 534
           VL + GF SGRH+WEVEVG + GWA G ARES                           R
Sbjct: 204 VLASCGFSSGRHHWEVEVGSKDGWAFGVARESV--------------------------R 237

Query: 535 RRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594
           R+   P  P  +  VW +  NG +Y A +S E++ LS     R   V LD E G + FY 
Sbjct: 238 RKGLTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSCGHLSR-VRVALDLEVGAVSFYA 294

Query: 595 AETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
            E + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 295 VEDMRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 329


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  178 bits (452), Expect = 1e-44
 Identities = 120/333 (36%), Positives = 168/333 (50%), Gaps = 38/333 (11%)

Query: 306 MKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLA 365
           M +E   V +EF  L  FL E++  L  RL E+      +     ++L  +  QLS+L +
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 366 EAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMF 425
           + QE +Q+  L  LQ+ K T +RC  V    P   S +      +  L   +++ M + F
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 426 CQAAR--------VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLG 477
            +  R        V+LTLDPDTA+P L+LS D +GVRL ER Q++ +HP RF  +  VL 
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
           + GF SGRH+WEVEVG + GWA G ARES                           RR+ 
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESV--------------------------RRKG 214

Query: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAET 597
             P  P  +  VW +  NG +Y A +S E++ LS     R   V LD E G + FY  E 
Sbjct: 215 LTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSCGHLSR-VRVALDLEVGAVSFYAVED 271

Query: 598 LAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
           + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 272 MRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 303


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  178 bits (452), Expect = 1e-44
 Identities = 120/333 (36%), Positives = 168/333 (50%), Gaps = 38/333 (11%)

Query: 306 MKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLA 365
           M +E   V +EF  L  FL E++  L  RL E+      +     ++L  +  QLS+L +
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 366 EAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMF 425
           + QE +Q+  L  LQ+ K T +RC  V    P   S +      +  L   +++ M + F
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 426 CQAAR--------VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLG 477
            +  R        V+LTLDPDTA+P L+LS D +GVRL ER Q++ +HP RF  +  VL 
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
           + GF SGRH+WEVEVG + GWA G ARES                           RR+ 
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESV--------------------------RRKG 214

Query: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAET 597
             P  P  +  VW +  NG +Y A +S E++ LS     R   V LD E G + FY  E 
Sbjct: 215 LTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSCGHLSR-VRVALDLEVGAVSFYAVED 271

Query: 598 LAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
           + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 272 MRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 303


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  178 bits (452), Expect = 1e-44
 Identities = 120/333 (36%), Positives = 168/333 (50%), Gaps = 38/333 (11%)

Query: 306 MKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLA 365
           M +E   V +EF  L  FL E++  L  RL E+      +     ++L  +  QLS+L +
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 366 EAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMF 425
           + QE +Q+  L  LQ+ K T +RC  V    P   S +      +  L   +++ M + F
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 426 CQAAR--------VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLG 477
            +  R        V+LTLDPDTA+P L+LS D +GVRL ER Q++ +HP RF  +  VL 
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
           + GF SGRH+WEVEVG + GWA G ARES                           RR+ 
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESV--------------------------RRKG 214

Query: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAET 597
             P  P  +  VW +  NG +Y A +S E++ LS     R   V LD E G + FY  E 
Sbjct: 215 LTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSCGHLSR-VRVALDLEVGAVSFYAVED 271

Query: 598 LAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
           + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 272 MRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 303


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  176 bits (446), Expect = 6e-44
 Identities = 105/324 (32%), Positives = 173/324 (53%), Gaps = 11/324 (3%)

Query: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232
           P P      TCP C++ F   SFRPN QLAN+V+ I ++      G  + ++ +C +H E
Sbjct: 47  PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104

Query: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292
            +  FCE DE  +CVVCRE+  H  H++  LE+    Y+ ++   ++ LRK  E +Q+++
Sbjct: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164

Query: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352
           ++E +R+  L +Q+ ++   V SEF  L +FL E+Q+ L  +L       L +       
Sbjct: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224

Query: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412
           +A +  + S L+ E +E++++    LL DI+ T  RCE  + + P   SP+  Q    DF
Sbjct: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283

Query: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464
              A+ +++  +MF +    +L       +LDP T+HP L+LS D +  + + + Q   D
Sbjct: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343

Query: 465 HPKRFSADCCVLGAQGFRSGRHYW 488
           +P+RF    CVL   G   GRH W
Sbjct: 344 NPQRFDRATCVLAHTGITGGRHTW 367



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 18/36 (50%), Positives = 24/36 (66%)

Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46
          V +L +E  C IC     +PV+I CGHNFCR C+T+
Sbjct: 7  VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  174 bits (442), Expect = 2e-43
 Identities = 133/459 (28%), Positives = 201/459 (43%), Gaps = 70/459 (15%)

Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVI--RQMHPTPGRGSRVTDQGICPKHQEALKLFC 238
           F CP+CR      + RPN  LA + +    R++ P P         G+C +H E L+LFC
Sbjct: 47  FPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVP--------PGLCGRHWEPLRLFC 98

Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298
           E D+  +C+VCRES+ H+ H++ P++E  + Y+ KL      L   ++ V  ++  E + 
Sbjct: 99  EDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKN 158

Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358
            T+ K ++KS+   +++EF +L  FL EE+    +RL +  E    +      +L +  A
Sbjct: 159 ATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIA 218

Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETFNRCE--EVQLQPPEVWSPDPCQPHSHDFLTDA 416
            L +L+ E  E+SQ   L LLQ+ KE   R E  +V      V     CQ          
Sbjct: 219 SLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQ--------IP 270

Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVR------------------LAER 458
           ++++M + F    +V + L  DTAHP L+ S + R V+                     R
Sbjct: 271 LMKEMLKRF----QVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWR 326

Query: 459 RQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGS 518
             +     +RF    CVLG   F SG+HYWEVE       AVG  RE     + +G    
Sbjct: 327 NPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCRE-----DVMGITDR 381

Query: 519 SVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRR 578
           S  S D                        +W +  +   Y        T         R
Sbjct: 382 SKMSPDVG----------------------IWAIYWSAAGYWPLIGFPGTPTQQEPALHR 419

Query: 579 FGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFF 617
            GVYLD   G + FY+A    H+HTFS + +  R+ PFF
Sbjct: 420 VGVYLDRGTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFF 457



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 24/37 (64%), Positives = 28/37 (75%)

Query: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48
          + +QEE  C ICLDYF DPVSI CGHNFCR C+ + W
Sbjct: 4  EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW 40


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  170 bits (431), Expect = 3e-42
 Identities = 133/463 (28%), Positives = 216/463 (46%), Gaps = 46/463 (9%)

Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
           +CP C  S+     + N  LAN+V+ ++++  +P  G +   + +C  H E L LFC+ D
Sbjct: 55  SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKK---RDLCDHHGEKLLLFCKED 111

Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
            + IC +C  S+ H+ H  V  EEV +E + KLQ  ++ L+K  E  +K++A      T 
Sbjct: 112 RKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTS 171

Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
            K Q+++E   + +EF +L   L  E+    +RL E  +  L +   A   L +Q   + 
Sbjct: 172 WKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVR 231

Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD-PCQPHSHDFLTDAIVRK 420
            L+++ + RSQ   + LLQD+       E  +L+ P++ S       H+ D      + +
Sbjct: 232 ELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPD------LSR 285

Query: 421 MSRMFCQAAR-----VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCV 475
           M +MF +        VD+TL+    +  L+LS D+R V        V   P +   +  V
Sbjct: 286 MLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGV 338

Query: 476 LGAQGFRSGRHYWEVEVGGRRGWAVGA-ARESTHHKEKVGPGGSSVGSGDASSSRHHHRR 534
           LG+Q F SG+HYWEV+V  +  W +G   R  + H + V               R    R
Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYV--------------VRRCANR 384

Query: 535 RRLHLPQQPLLQREVWCVGTNGK------RYQAQSSTEQTLLSPSEKPRRFGVYLDYEAG 588
           + L+   +PL     W +G   K           S  E   LS +  P R GV+LDYEAG
Sbjct: 385 QNLYTKYRPLF--GYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAG 442

Query: 589 RLGFYNAETLAH-VHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
            + F+N  +    ++ FS     + V+P+F   +    + LCP
Sbjct: 443 IVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 485



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 17/32 (53%), Positives = 24/32 (75%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45
          +QEE  C ICL+  T+P+S+ CGH+ CR C+T
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACIT 40


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  170 bits (431), Expect = 3e-42
 Identities = 133/463 (28%), Positives = 216/463 (46%), Gaps = 46/463 (9%)

Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241
           +CP C  S+     + N  LAN+V+ ++++  +P  G +   + +C  H E L LFC+ D
Sbjct: 55  SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKK---RDLCDHHGEKLLLFCKED 111

Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301
            + IC +C  S+ H+ H  V  EEV +E + KLQ  ++ L+K  E  +K++A      T 
Sbjct: 112 RKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTS 171

Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361
            K Q+++E   + +EF +L   L  E+    +RL E  +  L +   A   L +Q   + 
Sbjct: 172 WKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVR 231

Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD-PCQPHSHDFLTDAIVRK 420
            L+++ + RSQ   + LLQD+       E  +L+ P++ S       H+ D      + +
Sbjct: 232 ELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPD------LSR 285

Query: 421 MSRMFCQAAR-----VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCV 475
           M +MF +        VD+TL+    +  L+LS D+R V        V   P +   +  V
Sbjct: 286 MLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGV 338

Query: 476 LGAQGFRSGRHYWEVEVGGRRGWAVGA-ARESTHHKEKVGPGGSSVGSGDASSSRHHHRR 534
           LG+Q F SG+HYWEV+V  +  W +G   R  + H + V               R    R
Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYV--------------VRRCANR 384

Query: 535 RRLHLPQQPLLQREVWCVGTNGK------RYQAQSSTEQTLLSPSEKPRRFGVYLDYEAG 588
           + L+   +PL     W +G   K           S  E   LS +  P R GV+LDYEAG
Sbjct: 385 QNLYTKYRPLF--GYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAG 442

Query: 589 RLGFYNAETLAH-VHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630
            + F+N  +    ++ FS     + V+P+F   +    + LCP
Sbjct: 443 IVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 485



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 17/32 (53%), Positives = 24/32 (75%)

Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45
          +QEE  C ICL+  T+P+S+ CGH+ CR C+T
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACIT 40


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,332,555
Number of Sequences: 37866
Number of extensions: 1605158
Number of successful extensions: 33622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 596
Number of HSP's successfully gapped in prelim test: 642
Number of HSP's that attempted gapping in prelim test: 14992
Number of HSP's gapped (non-prelim): 8944
length of query: 630
length of database: 18,247,518
effective HSP length: 108
effective length of query: 522
effective length of database: 14,157,990
effective search space: 7390470780
effective search space used: 7390470780
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.