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Search of human proteins with 40807496
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807496 OTU domain containing 4 protein isoform 1 [Homo
sapiens]
(1048 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807496 OTU domain containing 4 protein isoform 1 [Homo sapi... 2144 0.0
gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sap... 2140 0.0
gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens] 296 9e-80
gi|55741677 SET domain containing 1A [Homo sapiens] 57 9e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 56 2e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 56 2e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 56 2e-07
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 52 4e-06
gi|119943102 CREB binding protein isoform b [Homo sapiens] 50 1e-05
gi|119943104 CREB binding protein isoform a [Homo sapiens] 50 1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 49 2e-05
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 49 2e-05
gi|209862789 microtubule associated monoxygenase, calponin and L... 47 9e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 46 2e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 46 2e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 46 2e-04
gi|116284392 mucin 2 precursor [Homo sapiens] 45 4e-04
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 45 4e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 6e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 44 8e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 44 8e-04
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 43 0.001
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 42 0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 42 0.002
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 42 0.002
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 42 0.002
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 42 0.002
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 42 0.002
gi|47132519 Ras association and pleckstrin homology domains 1 is... 42 0.002
>gi|40807496 OTU domain containing 4 protein isoform 1 [Homo sapiens]
Length = 1048
Score = 2144 bits (5556), Expect = 0.0
Identities = 1048/1048 (100%), Positives = 1048/1048 (100%)
Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV
Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV
Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
Query: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNELKNNGNSTSLPLSRK 180
MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNELKNNGNSTSLPLSRK
Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNELKNNGNSTSLPLSRK 180
Query: 181 VLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQ 240
VLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQ
Sbjct: 181 VLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQ 240
Query: 241 GIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKN 300
GIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKN
Sbjct: 241 GIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKN 300
Query: 301 PSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRER 360
PSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRER
Sbjct: 301 PSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRER 360
Query: 361 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 420
VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS
Sbjct: 361 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 420
Query: 421 NPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSS 480
NPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSS
Sbjct: 421 NPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSS 480
Query: 481 PSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGP 540
PSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGP
Sbjct: 481 PSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGP 540
Query: 541 TGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLY 600
TGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLY
Sbjct: 541 TGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLY 600
Query: 601 PGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQ 660
PGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQ
Sbjct: 601 PGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQ 660
Query: 661 AYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIG 720
AYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIG
Sbjct: 661 AYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIG 720
Query: 721 PPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNP 780
PPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNP
Sbjct: 721 PPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNP 780
Query: 781 FLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSV 840
FLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSV
Sbjct: 781 FLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSV 840
Query: 841 STVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQ 900
STVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQ
Sbjct: 841 STVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQ 900
Query: 901 ILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSED 960
ILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSED
Sbjct: 901 ILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSED 960
Query: 961 ENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQ 1020
ENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQ
Sbjct: 961 ENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQ 1020
Query: 1021 YHRNVRGRPFRGDRRRSGMGDGHRGQHT 1048
YHRNVRGRPFRGDRRRSGMGDGHRGQHT
Sbjct: 1021 YHRNVRGRPFRGDRRRSGMGDGHRGQHT 1048
>gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sapiens]
Length = 1049
Score = 2140 bits (5544), Expect = 0.0
Identities = 1048/1049 (99%), Positives = 1048/1049 (99%), Gaps = 1/1049 (0%)
Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV
Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV
Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
Query: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNE-LKNNGNSTSLPLSR 179
MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNE LKNNGNSTSLPLSR
Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSR 180
Query: 180 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 239
KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV
Sbjct: 181 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 240
Query: 240 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 299
QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK
Sbjct: 241 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 300
Query: 300 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 359
NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE
Sbjct: 301 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 360
Query: 360 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 419
RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS
Sbjct: 361 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 420
Query: 420 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 479
SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS
Sbjct: 421 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 480
Query: 480 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 539
SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG
Sbjct: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 540
Query: 540 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 599
PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL
Sbjct: 541 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600
Query: 600 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 659
YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH
Sbjct: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660
Query: 660 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 719
QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI
Sbjct: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 720
Query: 720 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 779
GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN
Sbjct: 721 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 780
Query: 780 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 839
PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS
Sbjct: 781 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 840
Query: 840 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 899
VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT
Sbjct: 841 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 900
Query: 900 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 959
QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE
Sbjct: 901 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 960
Query: 960 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1019
DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY
Sbjct: 961 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1020
Query: 1020 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1048
QYHRNVRGRPFRGDRRRSGMGDGHRGQHT
Sbjct: 1021 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1049
>gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens]
Length = 145
Score = 296 bits (757), Expect = 9e-80
Identities = 145/145 (100%), Positives = 145/145 (100%)
Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV
Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60
Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV
Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120
Query: 121 MELDTLEVADEDNSEISDSEDDSCK 145
MELDTLEVADEDNSEISDSEDDSCK
Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCK 145
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 57.0 bits (136), Expect = 9e-08
Identities = 89/414 (21%), Positives = 150/414 (36%), Gaps = 55/414 (13%)
Query: 183 KSLNPAVYRNVEY---EIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 239
+ LN + NV + + W +SK+ + K + AA Q + DK + +L G D
Sbjct: 808 RDLNRKMVENVAFGAFDQWWESKEEKAK-PFQNAAKQQAKEEDKEKTKLKEPGLLSLVDW 866
Query: 240 QGIHSENGPVLVEELG--------KKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHS 291
G +E + S +K P + S +K +PST +
Sbjct: 867 A---KSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDED 923
Query: 292 DVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQ----HAFSSHSSGSQSQKFSSEHKNLSR 347
D + K +P + P PP+ G Q +F+ S G ++ + SS K+
Sbjct: 924 DPEQE--KEAGEPGR-PGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEED 980
Query: 348 TPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPAL 407
+ D +R E D T +E+ +S E E + + L + ++ +
Sbjct: 981 DEED---EEDEDREEAVDTTKKETE---VSDGEDEESDSSSKCSLYADSDGENDSTSDSE 1034
Query: 408 SSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKR----PE 463
SSSS + S+S SS+ SS S + EE +++ + + R P
Sbjct: 1035 SSSSSSSSSSSSSS------SSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPT 1088
Query: 464 PSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPS 523
P+ +E ++ A SP P + S + PA P P+ P
Sbjct: 1089 PAPVEVPVPERVAG-------------SPVTPLPEQEASPARPA----GPTEESPPSAPL 1131
Query: 524 LPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVS 577
P PA P P +PIP+L + + + P P P +
Sbjct: 1132 RPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPAT 1185
Score = 33.9 bits (76), Expect = 0.82
Identities = 58/302 (19%), Positives = 98/302 (32%), Gaps = 45/302 (14%)
Query: 325 AFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEE---R 381
A S ++G ++ F S + R PS +++ + + + R +E
Sbjct: 867 AKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPE 926
Query: 382 REKQAIEESRLLYEIQNRDEQAFP-------ALSSSSVNQSASQSSNPCVQRKSSHVGDR 434
+EK+A E R + RDE+ + + S + ASQ S+ + +
Sbjct: 927 QEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEE 986
Query: 435 KGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAE 494
R +K+ + G + +L +D + + S S S +
Sbjct: 987 DEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS 1046
Query: 495 QKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQ 554
+ S S+ E PA +LP+ P P VP P P
Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPA--ALPSASPP---------PREVPVPTPA----- 1090
Query: 555 TLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIV 614
P VPV + P+ PLP+ + P P P E A +
Sbjct: 1091 ----------------PVEVPVPERVAGSPVTPLPEQEA---SPARPAGPTEESPPSAPL 1131
Query: 615 PP 616
P
Sbjct: 1132 RP 1133
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 56.2 bits (134), Expect = 2e-07
Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%)
Query: 405 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 458
P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q
Sbjct: 60 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 119
Query: 459 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 502
RP PS E + D + + ++S PSP + + A+
Sbjct: 120 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 179
Query: 503 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 561
L P L +P +TPA S P P P+ T T VP P S P
Sbjct: 180 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238
Query: 562 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 611
+ V H+ PSP P + + PL PL + P + P + +G
Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
Query: 612 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 666
P+SL Q G L F P+ + YP L A
Sbjct: 299 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 354
Query: 667 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 715
R P P P+ P + PA Q H + S+N +P
Sbjct: 355 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 410
Query: 716 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 767
P P S PPS QL Q+ +P Q ++L
Sbjct: 411 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469
Query: 768 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 793
+ PQP F +PF+ GP PI PP P
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 499
Score = 35.8 bits (81), Expect = 0.22
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%)
Query: 847 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 906
P+ R ++ +S + P T SS KA+T S V E +A P + R+R
Sbjct: 41 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 97
Query: 907 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 966
E V + E S K KT+++ P + ++ S DSR +E S D ++
Sbjct: 98 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 152
Query: 967 ILRS 970
RS
Sbjct: 153 DNRS 156
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 56.2 bits (134), Expect = 2e-07
Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%)
Query: 405 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 458
P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q
Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673
Query: 459 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 502
RP PS E + D + + ++S PSP + + A+
Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733
Query: 503 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 561
L P L +P +TPA S P P P+ T T VP P S P
Sbjct: 734 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 562 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 611
+ V H+ PSP P + + PL PL + P + P + +G
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 612 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 666
P+SL Q G L F P+ + YP L A
Sbjct: 853 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908
Query: 667 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 715
R P P P+ P + PA Q H + S+N +P
Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 964
Query: 716 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 767
P P S PPS QL Q+ +P Q ++L
Sbjct: 965 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 768 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 793
+ PQP F +PF+ GP PI PP P
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Score = 35.8 bits (81), Expect = 0.22
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%)
Query: 847 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 906
P+ R ++ +S + P T SS KA+T S V E +A P + R+R
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 651
Query: 907 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 966
E V + E S K KT+++ P + ++ S DSR +E S D ++
Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 706
Query: 967 ILRS 970
RS
Sbjct: 707 DNRS 710
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 56.2 bits (134), Expect = 2e-07
Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%)
Query: 405 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 458
P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q
Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673
Query: 459 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 502
RP PS E + D + + ++S PSP + + A+
Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733
Query: 503 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 561
L P L +P +TPA S P P P+ T T VP P S P
Sbjct: 734 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 562 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 611
+ V H+ PSP P + + PL PL + P + P + +G
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 612 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 666
P+SL Q G L F P+ + YP L A
Sbjct: 853 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908
Query: 667 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 715
R P P P+ P + PA Q H + S+N +P
Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 964
Query: 716 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 767
P P S PPS QL Q+ +P Q ++L
Sbjct: 965 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 768 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 793
+ PQP F +PF+ GP PI PP P
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Score = 35.8 bits (81), Expect = 0.22
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%)
Query: 847 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 906
P+ R ++ +S + P T SS KA+T S V E +A P + R+R
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 651
Query: 907 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 966
E V + E S K KT+++ P + ++ S DSR +E S D ++
Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 706
Query: 967 ILRS 970
RS
Sbjct: 707 DNRS 710
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 51.6 bits (122), Expect = 4e-06
Identities = 67/287 (23%), Positives = 112/287 (39%), Gaps = 30/287 (10%)
Query: 227 RLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESW---NTVSGKKMKKPS 283
R D K + +++ +++ +LG+ K KAPPP++ ++ K+ K S
Sbjct: 206 RKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLES 265
Query: 284 TSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHK 343
TS + P P P +A S P P + S S GS+S +S
Sbjct: 266 TSPKG-------GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRT 318
Query: 344 NLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDE-- 401
+ S + S D++ +D T E P E ++ +EES E + E
Sbjct: 319 SSSSSFS------DKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESA 372
Query: 402 QAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK- 460
Q+ P+ SSSS + S+ P ++ G + + +EE + DS G K
Sbjct: 373 QSSPSNSSSSSDSSSDSDFEP---SQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKT 429
Query: 461 ---RPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLS 504
R + + D A S PS+ P P ++ P + +S
Sbjct: 430 NPGRDSRLSFSDSESDNSADSSLPSRE-----PPPPQKPPPPNSKVS 471
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 50.1 bits (118), Expect = 1e-05
Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 20/160 (12%)
Query: 483 KSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTT----F 538
++ +L CP P Q P + H TP P + PA P++P+T
Sbjct: 801 QASQLPCP-PVTQSPLHPTPPPASTAAGMPSLQHTTP--PGMTPPQPAAPTQPSTPVSSS 857
Query: 539 GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP-VPVSIQAVNQPLMPLPQTLSLYQD 597
G T P P V S TQT +T A +QA +TP P PV +V P Q ++
Sbjct: 858 GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ 917
Query: 598 PLYPGFPCNEKG---DRAIVPPYSLC-------QTGEDLP 627
P PG P ++ D + P S+ Q G D+P
Sbjct: 918 P--PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 955
Score = 32.7 bits (73), Expect = 1.8
Identities = 64/292 (21%), Positives = 94/292 (32%), Gaps = 48/292 (16%)
Query: 504 SNPAPLLVSPEVHLT-PAVPSLPATVPAWPS-EPTTFGPTGVPAPIPVLSVTQTLTTGPD 561
S P+P P P+ P P PA P P + P G P+ T T P
Sbjct: 1843 SLPSPTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1901
Query: 562 SAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQ 621
S V P P +++A Q Q LY+ + P G P +
Sbjct: 1902 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAP 1959
Query: 622 TGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNP 681
++P+ + S P+ +P P
Sbjct: 1960 VSLNVPRPNQV------------SGPV-------------------------MPSMPPGQ 1982
Query: 682 WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPP---SQVSES 738
W Q+AP Q + MQ +A+V G P + PP SP + + S S
Sbjct: 1983 W-QQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2040
Query: 739 HGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPP 790
Q Q ++ QL+ A + + + K + QP P P L P P
Sbjct: 2041 SPQQQQQVLNILKSNPQLM-AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2091
Score = 32.0 bits (71), Expect = 3.1
Identities = 32/134 (23%), Positives = 46/134 (34%), Gaps = 16/134 (11%)
Query: 678 PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI--GPPTFSSPLVIPPSQV 735
P P + PA S + + A FP SV P + G PT P PP+Q
Sbjct: 1859 PSTPQTPQPPAQPQPSPVSMSPAGFP-----SVARTQPPTTVSTGKPTSQVPAPPPPAQP 1913
Query: 736 SESHGQLSYQADLESETPGQLLHADYEESL---------SGKNMFPQPSFGPNPFLGPVP 786
+ + + Q + E++ L + S+ G M P P P P
Sbjct: 1914 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 1973
Query: 787 IAPPFFPHVWYGYP 800
+ P P W P
Sbjct: 1974 VMPSMPPGQWQQAP 1987
Score = 30.8 bits (68), Expect = 7.0
Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 487 LECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTG-VPA 545
L P+P + + + P + P+ L P VP P + T P G P
Sbjct: 432 LSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPM 491
Query: 546 PIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 586
IP + T P + +S+ S +P S+ A N PLM
Sbjct: 492 NIPAGGI--TTDQQPPNLISE-----SALPTSLGATN-PLM 524
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 50.1 bits (118), Expect = 1e-05
Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 20/160 (12%)
Query: 483 KSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTT----F 538
++ +L CP P Q P + H TP P + PA P++P+T
Sbjct: 839 QASQLPCP-PVTQSPLHPTPPPASTAAGMPSLQHTTP--PGMTPPQPAAPTQPSTPVSSS 895
Query: 539 GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP-VPVSIQAVNQPLMPLPQTLSLYQD 597
G T P P V S TQT +T A +QA +TP P PV +V P Q ++
Sbjct: 896 GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ 955
Query: 598 PLYPGFPCNEKG---DRAIVPPYSLC-------QTGEDLP 627
P PG P ++ D + P S+ Q G D+P
Sbjct: 956 P--PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 993
Score = 32.7 bits (73), Expect = 1.8
Identities = 64/292 (21%), Positives = 94/292 (32%), Gaps = 48/292 (16%)
Query: 504 SNPAPLLVSPEVHLT-PAVPSLPATVPAWPS-EPTTFGPTGVPAPIPVLSVTQTLTTGPD 561
S P+P P P+ P P PA P P + P G P+ T T P
Sbjct: 1881 SLPSPTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1939
Query: 562 SAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQ 621
S V P P +++A Q Q LY+ + P G P +
Sbjct: 1940 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAP 1997
Query: 622 TGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNP 681
++P+ + S P+ +P P
Sbjct: 1998 VSLNVPRPNQV------------SGPV-------------------------MPSMPPGQ 2020
Query: 682 WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPP---SQVSES 738
W Q+AP Q + MQ +A+V G P + PP SP + + S S
Sbjct: 2021 W-QQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2078
Query: 739 HGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPP 790
Q Q ++ QL+ A + + + K + QP P P L P P
Sbjct: 2079 SPQQQQQVLNILKSNPQLM-AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2129
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 459 DKRPEPSTLENITDDKYATVSSPSKSKK----LECPSPAEQKPAEHVSLSNPAPLLVSPE 514
DKR + + L + T+ S ++ L P+P + + + P + P+
Sbjct: 438 DKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQ 497
Query: 515 VHLTPAVPSLPATVPAWPSEPTTFGPTG-VPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 573
L P VP P + T P G P IP + T P + +S+ S
Sbjct: 498 TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGI--TTDQQPPNLISE-----SA 550
Query: 574 VPVSIQAVNQPLM 586
+P S+ A N PLM
Sbjct: 551 LPTSLGATN-PLM 562
Score = 32.0 bits (71), Expect = 3.1
Identities = 32/134 (23%), Positives = 46/134 (34%), Gaps = 16/134 (11%)
Query: 678 PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI--GPPTFSSPLVIPPSQV 735
P P + PA S + + A FP SV P + G PT P PP+Q
Sbjct: 1897 PSTPQTPQPPAQPQPSPVSMSPAGFP-----SVARTQPPTTVSTGKPTSQVPAPPPPAQP 1951
Query: 736 SESHGQLSYQADLESETPGQLLHADYEESL---------SGKNMFPQPSFGPNPFLGPVP 786
+ + + Q + E++ L + S+ G M P P P P
Sbjct: 1952 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 2011
Query: 787 IAPPFFPHVWYGYP 800
+ P P W P
Sbjct: 2012 VMPSMPPGQWQQAP 2025
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.1 bits (118), Expect = 1e-05
Identities = 58/288 (20%), Positives = 109/288 (37%), Gaps = 14/288 (4%)
Query: 298 PKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSE---HKNLSRTPSQIIR 354
P+ ++ K P+ PP+ S VR+ + S + Q +K + ++ S +P + +
Sbjct: 153 PQRRAREAKQPAPEPPKPY--SLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK 210
Query: 355 KPDRERVEDFDHTSRESNYFGLSPEERRE----KQAIEESRLLYEIQNRDEQAFPALSSS 410
K +++ + S++ + +P+ +R+ K+ S R ++ A S+S
Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 411 SVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENI 470
S + S S+S + + ++ + R S E S G + + P T
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ 330
Query: 471 TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV-----SPEVHLTPAVPSLP 525
Y K K PSP+ ++ + P PLL SP+ T + P
Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390
Query: 526 ATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 573
P+ S P P +P S +++ P H + SP
Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Score = 41.6 bits (96), Expect = 0.004
Identities = 59/254 (23%), Positives = 94/254 (37%), Gaps = 41/254 (16%)
Query: 290 HSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTP 349
HSDV ++ A +AL P + S + SS SS S S SS S +
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 350 SQIIRKPDR-----ERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAF 404
S+ P + +RV +E+ G PE K+ S + +
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 405 PALSSSSVNQSASQSSNPCVQRKSSH---------------------VGDRKGSRRRMDT 443
+ SSSS + S+S SS+ SS G+R+ R
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682
Query: 444 EERKDKDSIHGHSQLDKR---PEPSTLENITDD--------KYATVSSPSKSKKLECPSP 492
+ +D S+ +S +++R P+PS + + + SPS ++ E PSP
Sbjct: 2683 DSLRDSRSL-SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
Query: 493 AEQKPAEHVSLSNP 506
+P H S +P
Sbjct: 2742 ---RPMRHRSSRSP 2752
Score = 40.8 bits (94), Expect = 0.007
Identities = 72/305 (23%), Positives = 120/305 (39%), Gaps = 42/305 (13%)
Query: 244 SENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSK 303
S + P + + S++L +P ++ + +S ++ S+ S R ++ S
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802
Query: 304 PIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEH-KNLSRTPSQIIRKPDRERVE 362
KA S PPR S S + QS SS H K S TP P + +
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP------PRQGSI- 855
Query: 363 DFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDE---QAFPALSSSS-VNQSASQ 418
TS ++N ++P+ R ++ + L +R + P + SS+ QS S+
Sbjct: 856 ----TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSR 911
Query: 419 SSNP-------CVQRKSSHVGDRKGSRRRMD--TEERKDKDSIHGHSQLDKRPEPSTLEN 469
SS+P R+ SH G S R+ T R+ + S+ S ++ R P
Sbjct: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR-SVSPCSNVESRLLP----- 965
Query: 470 ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVP 529
+Y+ S S K++ +P Q H +P P + + TP PSL +
Sbjct: 966 ----RYSHSGSSSPDTKVKPETPPRQ---SHSGSISPYPKVKAQ----TPPGPSLSGSKS 1014
Query: 530 AWPSE 534
P E
Sbjct: 1015 PCPQE 1019
Score = 38.9 bits (89), Expect = 0.026
Identities = 65/306 (21%), Positives = 107/306 (34%), Gaps = 47/306 (15%)
Query: 296 RGPKNPSKPIKAPSA--LPPRLQHPSGVRQHAFSSHS----------SGSQS-------- 335
R P S+ +APS LPP P AFS S +GSQS
Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482
Query: 336 -QKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLY 394
+ +H + P+ + D + S L P + R + S
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSS---- 2538
Query: 395 EIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHG 454
+ + SSSS + S+S S+ SS + + +R+ + K+++
Sbjct: 2539 ------SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Query: 455 HSQLDKRP-----EPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPL 509
+ P S+ + + ++ SS S S S + + S S+P+P
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 510 LVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHL 569
P+ PA P P P E + P PI L +++L+ P V +
Sbjct: 2653 KPGPQALPKPASPKKPP-----PGERRSRSPR---KPIDSLRDSRSLSYSP---VERRRP 2701
Query: 570 TPSPVP 575
+P P P
Sbjct: 2702 SPQPSP 2707
Score = 35.8 bits (81), Expect = 0.22
Identities = 65/306 (21%), Positives = 114/306 (37%), Gaps = 34/306 (11%)
Query: 299 KNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNL-------SRTPSQ 351
+ P++ ++ S P R S R A S ++ S ++L SRTP +
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 352 IIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSS 411
R ++ TS+ + SPE ++ + + SR L +++ A S S
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK------AKSRLS 774
Query: 412 VNQSASQSSNPCVQRKS------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPS 465
+ +S S SS PC ++KS S G + + R S Q K P
Sbjct: 775 LRRSLSGSS-PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833
Query: 466 TLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLP 525
+ + + +P + + P EQ V+ + SP+ L PS
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQS----VTPQRRSCFESSPDPELKSRTPSRH 889
Query: 526 ATVPAWP-----SEPTTFGPTGVPAPIP----VLSVTQTLTTGPDSAVSQAHLTPSPVPV 576
+ + P S P P+ +P P ++S Q +G S+ S + +T P
Sbjct: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG-SSSPSPSRVTSRTTPR 948
Query: 577 SIQAVN 582
++V+
Sbjct: 949 RSRSVS 954
Score = 33.5 bits (75), Expect = 1.1
Identities = 73/319 (22%), Positives = 114/319 (35%), Gaps = 49/319 (15%)
Query: 215 GLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVL-VEELGKK---HTSKNLKAPPPES 270
G + G +V+ D NG FLN E P L ++E + H+S L E
Sbjct: 1340 GTEMNTGFSSEVKEDLNGPFLN------QLETDPSLDMKEQSTRSSGHSSSELSPDAVE- 1392
Query: 271 WNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQH--PSGVRQHAFSS 328
K +S Q+ S V P+ PS+ ++ SA P ++ P + + S
Sbjct: 1393 ---------KAGMSSNQSISSPVLDAVPRTPSRE-RSSSASSPEMKDGLPRTPSRRSRSG 1442
Query: 329 HSSGSQSQKFSSEHKNLSRTP---SQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQ 385
S G + + +LS + I R P R R E +S E +P R
Sbjct: 1443 SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE--CDSSPEPKALPQTPRPRSRSP 1500
Query: 386 AIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEE 445
+ E R+ S SSV+Q + + P QR S + +E
Sbjct: 1501 SSPELNNKCLTPQRERSG----SESSVDQK-TVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 446 RKDKDS-----------IHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAE 494
R + DS + S+ PE + ++ + + SSP K P
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK-----PRA 1610
Query: 495 QKPAEHVSLSNPAPLLVSP 513
A+ S S+P P +P
Sbjct: 1611 APRAQSGSDSSPEPKAPAP 1629
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 48.9 bits (115), Expect = 2e-05
Identities = 82/343 (23%), Positives = 127/343 (37%), Gaps = 52/343 (15%)
Query: 269 ESWNTVSGKKMKKPSTSGQNFHSDVD-------YRGPKNPSKPIKAPSALPPRLQHPSGV 321
E T KK ++ T+G +FHS Y + + + L R + P +
Sbjct: 115 EKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLC--QHLGKRKKMPKAL 172
Query: 322 RQHAFSSHSS-GSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDH-TSRESNYFGLSPE 379
RQ +S S S+ S E K R+ S RER+ D +S + YF S
Sbjct: 173 RQLKPGQNSCRDSDSESASGESKGFHRSSS-------RERLSDSSAPSSLGTGYFCDSDS 225
Query: 380 ERREKQAIEESRLLYE--IQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGS 437
++ EK + S L+ I N+D P L ++ + SQ + P V + S
Sbjct: 226 DQEEKASDASSEKLFNTVIVNKD----PELGVGTLPEHDSQDAGPIVPKISG-------- 273
Query: 438 RRRMDTEERKDKDSIHGHSQLDKRP--EPSTLENITDDKYATVSSPSKSKKLECPSPAEQ 495
++ + K +D K P EP L++ + P +L PSP
Sbjct: 274 ---LERSQEKSQDCC-------KEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPD 323
Query: 496 KPAEHVSLSNPAPLLVS-----PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVL 550
+ P PL PE L PA P P P PT +P P+
Sbjct: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLP-PVQAH 381
Query: 551 SVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLS 593
Q+L+ P SA + + L+ + + S + P P +S
Sbjct: 382 PSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423
Score = 30.8 bits (68), Expect = 7.0
Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 13/153 (8%)
Query: 252 EELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSAL 311
E + K+H+S P P V+ + ST H + + R P + + S
Sbjct: 821 ESVEKRHSSH----PSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 876
Query: 312 PPRL--QHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSR 369
L H G + + E K L+R PS +R P E +SR
Sbjct: 877 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 936
Query: 370 ESNYFGLSPEERREKQAIEESRLLYEIQNRDEQ 402
E+ E R+ + A E + E++ ++E+
Sbjct: 937 EA-------EPRKGEPAYENPKKSSEVKVKEER 962
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 48.9 bits (115), Expect = 2e-05
Identities = 82/343 (23%), Positives = 127/343 (37%), Gaps = 52/343 (15%)
Query: 269 ESWNTVSGKKMKKPSTSGQNFHSDVD-------YRGPKNPSKPIKAPSALPPRLQHPSGV 321
E T KK ++ T+G +FHS Y + + + L R + P +
Sbjct: 115 EKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLC--QHLGKRKKMPKAL 172
Query: 322 RQHAFSSHSS-GSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDH-TSRESNYFGLSPE 379
RQ +S S S+ S E K R+ S RER+ D +S + YF S
Sbjct: 173 RQLKPGQNSCRDSDSESASGESKGFHRSSS-------RERLSDSSAPSSLGTGYFCDSDS 225
Query: 380 ERREKQAIEESRLLYE--IQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGS 437
++ EK + S L+ I N+D P L ++ + SQ + P V + S
Sbjct: 226 DQEEKASDASSEKLFNTVIVNKD----PELGVGTLPEHDSQDAGPIVPKISG-------- 273
Query: 438 RRRMDTEERKDKDSIHGHSQLDKRP--EPSTLENITDDKYATVSSPSKSKKLECPSPAEQ 495
++ + K +D K P EP L++ + P +L PSP
Sbjct: 274 ---LERSQEKSQDCC-------KEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPD 323
Query: 496 KPAEHVSLSNPAPLLVS-----PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVL 550
+ P PL PE L PA P P P PT +P P+
Sbjct: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLP-PVQAH 381
Query: 551 SVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLS 593
Q+L+ P SA + + L+ + + S + P P +S
Sbjct: 382 PSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423
Score = 30.8 bits (68), Expect = 7.0
Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 13/153 (8%)
Query: 252 EELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSAL 311
E + K+H+S P P V+ + ST H + + R P + + S
Sbjct: 845 ESVEKRHSSH----PSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900
Query: 312 PPRL--QHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSR 369
L H G + + E K L+R PS +R P E +SR
Sbjct: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960
Query: 370 ESNYFGLSPEERREKQAIEESRLLYEIQNRDEQ 402
E+ E R+ + A E + E++ ++E+
Sbjct: 961 EA-------EPRKGEPAYENPKKSSEVKVKEER 986
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 47.0 bits (110), Expect = 9e-05
Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 56/344 (16%)
Query: 319 SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVE-------DFDHTSRES 371
+G + SS S ++ E + PS + P +E V + S
Sbjct: 925 TGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEAS 984
Query: 372 NYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQ---SSNPCVQRKS 428
FG EE E++ E + +E+ SS + NQ Q +++P +
Sbjct: 985 KSFGPGNEEEEEEEEEYEEEEEEDYDEEEEE-----SSEAGNQRLQQVMHAADPLEIQAD 1039
Query: 429 ---SHVGDRKGSRRRMDTEE-------------RKDKDS----IHGHSQLDKRPEPSTLE 468
+H+ +R+ R E +D DS I G + D P + E
Sbjct: 1040 VHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAE 1099
Query: 469 NITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT--PAVPSLPA 526
+ DD++ + S ++L P PAE + + +S L + H P+ + P
Sbjct: 1100 -LDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPI 1158
Query: 527 TVPAWPS-------EPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTP-----SPV 574
P + P+T GP P P T P+ + L P +
Sbjct: 1159 RSPQESALLFIPVHSPSTEGPQLPPVP------AATQEKSPEERLFPEPLLPKEKPKADA 1212
Query: 575 PVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYS 618
P ++AV+ P+ P TL + P+ PG P + A PP S
Sbjct: 1213 PSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPS 1256
Score = 33.5 bits (75), Expect = 1.1
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 13/105 (12%)
Query: 485 KKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP 544
+K + +P++ K S P L PE TP P P +P T P
Sbjct: 1206 EKPKADAPSDLKAVHSPIRSQPVTL---PEAR-TPVSPGSPQP------QPPVAASTPPP 1255
Query: 545 APIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLP 589
+P+P+ S Q T + +Q+ + P P + PL PLP
Sbjct: 1256 SPLPICSQPQPSTEATVPSPTQSPIRFQPAPAK---TSTPLAPLP 1297
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 46.2 bits (108), Expect = 2e-04
Identities = 77/345 (22%), Positives = 122/345 (35%), Gaps = 32/345 (9%)
Query: 275 SGKKMKKPSTSGQNFHSDVDYRGPKNPSKPI--KAPSALPPRLQHPSGVRQHAFSSHSSG 332
S KK PS + Q S R PK P+K K + +H Q + SS SS
Sbjct: 74 SSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132
Query: 333 SQSQKF----SSEHKNLSRTPSQIIRKPDRER------------VEDFDHTSRESNYFGL 376
S S SS++ +R + ++ D ++ V D + ++ F +
Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 192
Query: 377 SPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGD 433
+ + Q + S ++ + P S +S S + + V+ K + +
Sbjct: 193 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 252
Query: 434 RKGSRRRMD-TEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSP 492
++ S + T K+ SI S D P L T T P+ + E P+P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-PTP 311
Query: 493 AEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGV--PAPIPVL 550
K + P P + TP P+ P T + P+ P PT PAP
Sbjct: 312 TTPKEPASTTPKEPTPTTIK-SAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 551 SVTQTLTTGPDSAVSQAHLT----PSPVPVSIQAVNQPLMPLPQT 591
T T P +++ T P+P A P P P T
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414
Score = 37.4 bits (85), Expect = 0.075
Identities = 74/365 (20%), Positives = 133/365 (36%), Gaps = 31/365 (8%)
Query: 252 EELGKKHT-SKNLKAPPPESWNTVSG--KKMKKPSTSGQNFHSDVDYRGPKNP-SKPIKA 307
EE+ ++H+ S+N ++ S ++ S +K+K S N + N ++ K
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170
Query: 308 PSALPPRLQHP-SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKP--DRERVEDF 364
P+ PP + SG+ F + + + ++H +S +P KP R +
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKPINPRPSLPPN 226
Query: 365 DHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPC- 423
TS+E++ ++ E E + + + E+ A + S+ +++++ P
Sbjct: 227 SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGK-EKTTSAKETQSIEKTSAKDLAPTS 284
Query: 424 -VQRKSSHVGDRKGSRRRMDT-EERKDKDSIHGHSQLDKRPEPSTLENI--TDDKYATVS 479
V K + + + T +E S K P P+T+++ T + A +
Sbjct: 285 KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 344
Query: 480 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT------------PAVPSLPA- 526
+ S + P+P K + PAP T P P PA
Sbjct: 345 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 404
Query: 527 TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 586
T P P+ T PT P + + T P A P+P A P
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464
Query: 587 PLPQT 591
P P T
Sbjct: 465 PAPTT 469
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%)
Query: 460 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 518
K P P+T E T K ++P K PA P E + P +P+
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 578
S P T T PT P P + TT P P+P
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 542
Query: 579 QAVNQPLMPLPQT 591
A P P P T
Sbjct: 543 PAPTTPKEPAPTT 555
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P P+T + +P+ K+ +P E P L+ P ++P P
Sbjct: 549 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 579
A + P P EPT PT P P T P +A P+P
Sbjct: 600 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 647
Query: 580 AVNQPLMPLPQT 591
A P P P T
Sbjct: 648 APTTPKEPAPTT 659
Score = 34.7 bits (78), Expect = 0.48
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
++P P+T E + T P+ + E P+P K A + PAP TP
Sbjct: 597 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T P S P+
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 709
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 710 PTTPKGTAPTTPKEPAPTT 728
Score = 34.3 bits (77), Expect = 0.63
Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T ++ T + A ++ S + PSP K + PAP
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 576
TP P+ P P EP PT P P TT ++A + LTP+ P
Sbjct: 539 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 589
Query: 577 SIQAVNQPLMPLPQT 591
+ A P P P T
Sbjct: 590 KL-APTTPEKPAPTT 603
Score = 33.9 bits (76), Expect = 0.82
Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P+TL K ++P K E +P K + PAP TP
Sbjct: 669 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 721
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T GP S S P+
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 778
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 779 PTTPKETAPTTPKEPAPTT 797
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T + T K ++P K E +P K + PAP
Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 576
TP P+ P+ P T PT P + T+ PD + + P+P +
Sbjct: 789 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 848
Query: 577 SIQAVNQPLMPLPQT 591
+ +P +P +T
Sbjct: 849 E-NSPKEPGVPTTKT 862
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 46.2 bits (108), Expect = 2e-04
Identities = 77/345 (22%), Positives = 122/345 (35%), Gaps = 32/345 (9%)
Query: 275 SGKKMKKPSTSGQNFHSDVDYRGPKNPSKPI--KAPSALPPRLQHPSGVRQHAFSSHSSG 332
S KK PS + Q S R PK P+K K + +H Q + SS SS
Sbjct: 115 SSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173
Query: 333 SQSQKF----SSEHKNLSRTPSQIIRKPDRER------------VEDFDHTSRESNYFGL 376
S S SS++ +R + ++ D ++ V D + ++ F +
Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 233
Query: 377 SPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGD 433
+ + Q + S ++ + P S +S S + + V+ K + +
Sbjct: 234 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 293
Query: 434 RKGSRRRMD-TEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSP 492
++ S + T K+ SI S D P L T T P+ + E P+P
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-PTP 352
Query: 493 AEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGV--PAPIPVL 550
K + P P + TP P+ P T + P+ P PT PAP
Sbjct: 353 TTPKEPASTTPKEPTPTTIK-SAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 551 SVTQTLTTGPDSAVSQAHLT----PSPVPVSIQAVNQPLMPLPQT 591
T T P +++ T P+P A P P P T
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455
Score = 37.4 bits (85), Expect = 0.075
Identities = 74/365 (20%), Positives = 133/365 (36%), Gaps = 31/365 (8%)
Query: 252 EELGKKHT-SKNLKAPPPESWNTVSG--KKMKKPSTSGQNFHSDVDYRGPKNP-SKPIKA 307
EE+ ++H+ S+N ++ S ++ S +K+K S N + N ++ K
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211
Query: 308 PSALPPRLQHP-SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKP--DRERVEDF 364
P+ PP + SG+ F + + + ++H +S +P KP R +
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKPINPRPSLPPN 267
Query: 365 DHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPC- 423
TS+E++ ++ E E + + + E+ A + S+ +++++ P
Sbjct: 268 SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGK-EKTTSAKETQSIEKTSAKDLAPTS 325
Query: 424 -VQRKSSHVGDRKGSRRRMDT-EERKDKDSIHGHSQLDKRPEPSTLENI--TDDKYATVS 479
V K + + + T +E S K P P+T+++ T + A +
Sbjct: 326 KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 385
Query: 480 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT------------PAVPSLPA- 526
+ S + P+P K + PAP T P P PA
Sbjct: 386 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 445
Query: 527 TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 586
T P P+ T PT P + + T P A P+P A P
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505
Query: 587 PLPQT 591
P P T
Sbjct: 506 PAPTT 510
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%)
Query: 460 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 518
K P P+T E T K ++P K PA P E + P +P+
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 578
S P T T PT P P + TT P P+P
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 583
Query: 579 QAVNQPLMPLPQT 591
A P P P T
Sbjct: 584 PAPTTPKEPAPTT 596
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P P+T + +P+ K+ +P E P L+ P ++P P
Sbjct: 590 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 579
A + P P EPT PT P P T P +A P+P
Sbjct: 641 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 688
Query: 580 AVNQPLMPLPQT 591
A P P P T
Sbjct: 689 APTTPKEPAPTT 700
Score = 34.7 bits (78), Expect = 0.48
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
++P P+T E + T P+ + E P+P K A + PAP TP
Sbjct: 638 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T P S P+
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 750
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 751 PTTPKGTAPTTPKEPAPTT 769
Score = 34.3 bits (77), Expect = 0.63
Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T ++ T + A ++ S + PSP K + PAP
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 576
TP P+ P P EP PT P P TT ++A + LTP+ P
Sbjct: 580 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 630
Query: 577 SIQAVNQPLMPLPQT 591
+ A P P P T
Sbjct: 631 KL-APTTPEKPAPTT 644
Score = 33.9 bits (76), Expect = 0.82
Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P+TL K ++P K E +P K + PAP TP
Sbjct: 710 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 762
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T GP S S P+
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 819
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 820 PTTPKETAPTTPKEPAPTT 838
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T + T K ++P K E +P K + PAP
Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 576
TP P+ P+ P T PT P + T+ PD + + P+P +
Sbjct: 830 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 889
Query: 577 SIQAVNQPLMPLPQT 591
+ +P +P +T
Sbjct: 890 E-NSPKEPGVPTTKT 903
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 45.8 bits (107), Expect = 2e-04
Identities = 70/317 (22%), Positives = 115/317 (36%), Gaps = 37/317 (11%)
Query: 256 KKHTSKNLKAPPPE---SWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIK------ 306
++ T PPP S + V ++ S SG + S R P KP K
Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS-RSRSPPKKPPKRTSSPP 382
Query: 307 ------APSALPPRLQH-PSGVRQHAFSSHSSGSQSQKFSSEHKNLS----RTPSQIIRK 355
+PSA PPR +H PS + S + Q + +S RT ++ +
Sbjct: 383 RKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH 442
Query: 356 PDRERVEDFDHTSRESNY-FGLSPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSS 411
E+ E + S E++ K A +S R Y QN+ + SSSS
Sbjct: 443 KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSS 502
Query: 412 VNQSASQS--SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLEN 469
++ +S N V R+ H R S +R+ + S G + P P+
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASP---SPRKRQKETSPRGRRRRSPSPPPTRRR- 558
Query: 470 ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEV--HLTPAVPSLPAT 527
+ + + P + ++ P P + P+ +P+P SP + +P+ P T
Sbjct: 559 ----RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614
Query: 528 VPAWPSEPTTFGPTGVP 544
P P+ P
Sbjct: 615 ASPPPPPKRRASPSPPP 631
Score = 30.8 bits (68), Expect = 7.0
Identities = 28/141 (19%), Positives = 52/141 (36%), Gaps = 9/141 (6%)
Query: 403 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRP 462
AF L + Q + +K D++ + + E++++ S + + P
Sbjct: 122 AFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER-SRSPRRRKSRSP 180
Query: 463 EPSTLENIT--DDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPA 520
P + + K + SP K PSPA +K + L P+ + P V +
Sbjct: 181 SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS 240
Query: 521 VPSL-----PATVPAWPSEPT 536
+ P +P P EP+
Sbjct: 241 TSDILKVPKPEPIPE-PKEPS 260
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 45.1 bits (105), Expect = 4e-04
Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 9/147 (6%)
Query: 462 PEPSTLENITDDKYATVSSPSKS------KKLECPSPAEQKPAEHVSLSNPAPLLVSPEV 515
P P T T T S P+ + P P + + P SP
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582
Query: 516 HLTPAVPSLPATVP---AWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPS 572
TP+ P++ T P PS PTT T P P T +T + TPS
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642
Query: 573 PVPVSIQAVNQPLMPLPQTLSLYQDPL 599
P P + P P T + P+
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPI 1669
Score = 40.0 bits (92), Expect = 0.012
Identities = 35/141 (24%), Positives = 48/141 (34%), Gaps = 9/141 (6%)
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 521
P P T T S P+ + PSP P+ + + P +P T +
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTT-----PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 522 --PSLPATVP--AWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVS 577
P+ T+P PS PTT T P P T +T + TPSP P +
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568
Query: 578 IQAVNQPLMPLPQTLSLYQDP 598
P P T + P
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPP 1589
Score = 39.7 bits (91), Expect = 0.015
Identities = 38/139 (27%), Positives = 49/139 (35%), Gaps = 18/139 (12%)
Query: 462 PEPSTLENITDDKYATV------SSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEV 515
P P T IT T SP + P P + S P +P
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 516 HLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVP 575
TP+ P + PS PTT T P+P S T TT P S TPSP P
Sbjct: 1678 TTTPSSP-----ITTTPSPPTTTMTT--PSPTTTPSSPITTTTTPSSTT-----TPSPPP 1725
Query: 576 VSIQAVNQPLMPLPQTLSL 594
++ + P P T ++
Sbjct: 1726 TTMTTPSPTTTPSPPTTTM 1744
Score = 39.3 bits (90), Expect = 0.020
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 18/129 (13%)
Query: 462 PEPSTLEN---ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSL--SNPAPLLVSPEVH 516
P P+T T T ++PS P P+ ++ S P + +P
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT 1702
Query: 517 LTPAVPSLPATVPA---WPSEP----TTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHL 569
TP+ P T P+ PS P TT PT P+P T T+TT P + S + L
Sbjct: 1703 TTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP-----PTTTMTTLPPTTTS-SPL 1756
Query: 570 TPSPVPVSI 578
T +P+P SI
Sbjct: 1757 TTTPLPPSI 1765
Score = 37.0 bits (84), Expect = 0.097
Identities = 38/147 (25%), Positives = 56/147 (38%), Gaps = 16/147 (10%)
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 521
P P+ T T ++P P P P S S+P + L PA+
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 4245
Query: 522 PSLPATVPAWPSEPTTF--GPTGVPAPIPVLSV----TQTLTTGPDSAVSQAHL------ 569
P+ P+ PTT G T P P S T+ TTG SA + + +
Sbjct: 4246 EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305
Query: 570 --TPSPVPVSIQAV--NQPLMPLPQTL 592
TP+P P+S ++ L P P ++
Sbjct: 4306 AWTPTPTPLSTPSIIRTTGLRPYPSSV 4332
Score = 36.2 bits (82), Expect = 0.17
Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 3/89 (3%)
Query: 485 KKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP 544
K + PSP P+ + + P +P T P T P+ P TT P P
Sbjct: 1394 KCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP---P 1450
Query: 545 APIPVLSVTQTLTTGPDSAVSQAHLTPSP 573
P ++ T T P + S TPSP
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSP 1479
Score = 36.2 bits (82), Expect = 0.17
Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 13/145 (8%)
Query: 477 TVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPA---WPS 533
T ++P + P+ P + + P S + TP+ P+ T P+ PS
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706
Query: 534 EPTTF----GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMP-- 587
P T T P+P P T + TT P + P P S PL P
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP-PTTTSSPLTTTPLPPSI 1765
Query: 588 LPQTLSLYQ--DPLYPGFP-CNEKG 609
P T S + P P P CN G
Sbjct: 1766 TPPTFSPFSTTTPTTPCVPLCNWTG 1790
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 8/145 (5%)
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSL----SNPAPLLVSPEVHL 517
P P T T S P+ + P+ P + + P+P + +
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465
Query: 518 TPAVPSLPATVPA----WPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 573
PS P T P+ PS PTT T P P T +T + TPSP
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525
Query: 574 VPVSIQAVNQPLMPLPQTLSLYQDP 598
+ P P T + P
Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPP 1550
Score = 34.7 bits (78), Expect = 0.48
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 522 PSLPATVPA-WPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQA 580
PS P T P+ P+ TT PT P+P + T TT P ++ TP P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT-TTPPPTTTPSPP 1457
Query: 581 VNQPLMPLPQT 591
++ P P T
Sbjct: 1458 ISTTTTPPPTT 1468
Score = 33.9 bits (76), Expect = 0.82
Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 10/99 (10%)
Query: 488 ECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP--- 544
E P+P P + P P + T + + P P+ T PT P
Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 1949
Query: 545 ----APIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 579
P P + TQT TT P + + +TP+P P Q
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQ 1986
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 2/86 (2%)
Query: 503 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTF-GPTGVPAPIPVLSVTQTLTTGPD 561
++ P+P +P T P T P+ P+ TT PT P+P + T TT P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 562 SAVSQAHLTPSPVPVSIQAVNQPLMP 587
+S TP P P P
Sbjct: 1456 PPISTT-TTPPPTTTPSPPTTTPSPP 1480
Score = 33.1 bits (74), Expect = 1.4
Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 8/122 (6%)
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 521
P P T T SSP + P+ P+ + S+P +P TP+
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSP-PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 522 PSLPATVPA---WPSEPTT----FGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 574
P T P+ PS PTT PT +P+ + ++T S S T V
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Query: 575 PV 576
P+
Sbjct: 1784 PL 1785
Score = 30.8 bits (68), Expect = 7.0
Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 13/125 (10%)
Query: 465 STLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSL 524
+T EN T +++ + P+ + ++ + +P TP +
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947
Query: 525 PATVPAWPSEPTTFG---PTGVP-------APIPVLSVTQTLTTGPDSAVSQAHLTPSPV 574
T P+ PT G PT P P P + TQT TT P + + +TP+P
Sbjct: 1948 TTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPT 2004
Query: 575 PVSIQ 579
P Q
Sbjct: 2005 PTGTQ 2009
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 45.1 bits (105), Expect = 4e-04
Identities = 66/362 (18%), Positives = 129/362 (35%), Gaps = 27/362 (7%)
Query: 245 ENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKP 304
+NGP LG PPPE + P++ P P P
Sbjct: 747 QNGPKPPATLGADGPPPGPPTPPPED---IPAPTEPTPASEATG--------APTPPPAP 795
Query: 305 IKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRT-------PSQIIRKPD 357
+PSA PP + + A + + QK + + T S+ + +
Sbjct: 796 -PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAE 854
Query: 358 RERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSAS 417
+ D + E+ G E++E + + +D + S+ V+++
Sbjct: 855 EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEG 914
Query: 418 QSSNPCVQRKSSHV---GDRKGS---RRRMDTEERKDKDSIHGHSQLDKRPEPSTLENIT 471
N + + S + GD + + ++ +D ++ K + + Q+ K EP +
Sbjct: 915 GDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAP 974
Query: 472 DDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAW 531
P ++ + E +P + + +PAP E P+ A
Sbjct: 975 TKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP-ADKEAEKPVFFPAFAAEAQKL 1033
Query: 532 PSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQT 591
P +P + +G+P P+P V + PD + P+P+ + +P++P P T
Sbjct: 1034 PGDPPCW-TSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1092
Query: 592 LS 593
+S
Sbjct: 1093 IS 1094
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 44.3 bits (103), Expect = 6e-04
Identities = 98/406 (24%), Positives = 144/406 (35%), Gaps = 86/406 (21%)
Query: 405 PALSSSSVNQSASQSSNPCVQRKSSHVG--DRKGSRRRMDTEERKDKDSIHGHSQLD--- 459
P S SS ++ ++ +P +R+ S G R SR + + G S
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 460 -----KRPEPSTLENITDDKY-------ATVSSPSKSKKLECPSPAEQKPAEHVSLSNPA 507
+P+P L+ + + A P S L PSP+ K + P
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK-------ARPV 317
Query: 508 PLLVSPEVHLTPAVPSLPATVPAWP--SEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVS 565
P P+ TP LPAT+P P + P P AP + ++ T P A
Sbjct: 318 P---PPDNAATP----LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 566 QAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGED 625
P P S+Q + P + +P +L+ PP L +
Sbjct: 371 SMTTPPMQAPPSLQTI--PPIQVPHSLT---------------SPSLQAPPSPLALSS-- 411
Query: 626 LPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQE 685
L+ +LG S + A HS+L + A P P P +P Q
Sbjct: 412 -------LQATTSLG----SPTLQATHSFL-TMSPRQTQASLTSPSRPASTPPDSPPLQ- 458
Query: 686 APAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQ 745
AP + S P+QT S P + P SSPL I P Q S S Q
Sbjct: 459 APLSLPASP--------PLQTSLS-------PAVSP--LSSPLTIHPLQALSSLASHSPQ 501
Query: 746 ADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVP-IAPP 790
A L S L + + SL+ ++ P+ P L +P +APP
Sbjct: 502 APLSSLIMPPL---ETQSSLAPPSLQTPPASLTTPPLENLPSLAPP 544
Score = 39.7 bits (91), Expect = 0.015
Identities = 76/325 (23%), Positives = 106/325 (32%), Gaps = 40/325 (12%)
Query: 476 ATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEP 535
A+ S + L P Q SL P L +P + P++ P + P
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 536 TTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLY 595
PAP P+ + LTT P S P P ++ + PL LP
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL--ASPPLQGLP------ 607
Query: 596 QDPLYP-GFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSY 654
PL P P + +PP + P L A P AP++
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP----------LSPLATPSPQ-APNAL 656
Query: 655 LYPLHQAYLAACRMYPKVPVPVYPHNPWFQE--APAAQNESDCTCTDAHFPMQTEASVNG 712
L QA + P P P +P +P+A S + A P+Q S
Sbjct: 657 AVHLLQAPFSP----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712
Query: 713 Q-------MPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESL 765
P P+ PP + PL +PPS + +S A P L +
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP--PMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 766 SGKNMFPQPSFGPNPFLGPVPIAPP 790
S P S +P P P APP
Sbjct: 771 S-----PPASLPMSPLAKPPPQAPP 790
Score = 34.3 bits (77), Expect = 0.63
Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 27/113 (23%)
Query: 490 PSPAEQKPAEHVSLSNPA--PLLVSPEVHLTPAVP-SLPATVPAWPSEPTTFGPTGVPAP 546
PSP P ++ P P L +P + P+ P S P P PS P P P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 547 -------IPVLSV------TQTL-------TTGPDSAVSQAHLT----PSPVP 575
P+L V + TL T GPD++VS LT P P P
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 43.9 bits (102), Expect = 8e-04
Identities = 80/337 (23%), Positives = 128/337 (37%), Gaps = 59/337 (17%)
Query: 302 SKPIKAPSALPPRLQHPSGVRQHAFSSHSSG-SQSQKFSSEHKNLSRTPSQIIRKPDRER 360
SK + S LP R S R A+S HSS S+ ++ SS ++ S +P +R P
Sbjct: 338 SKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP---VRLPLNS- 393
Query: 361 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 420
L E R+K+ + ++ ++ + P N S
Sbjct: 394 --------------SLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 421 NPCVQRKSSHVGDRKGSR--------RRMDTEERKDKDSIHGHSQLDKRPEPSTLENITD 472
+ +K + S ++TE + D+ G +LD+ E ++++
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDT--GKVKLDENSEKHLVKDLKA 497
Query: 473 DKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT-------------- 518
T S + K E +P E + +E + P P + SP L
Sbjct: 498 Q--GTRDSKPIALKEEIVTPKETETSEKET-PPPLPTIASPPPPLPTTTPPPQTPPLPPL 554
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTL---TTGPDSAVSQAHLTPSPVP 575
P +P+LP P PS+P + VPA S T TL T SAVS + PV
Sbjct: 555 PPIPALPQQPPLPPSQPAF---SQVPA-----SSTSTLPPSTHSKTSAVSSQANSQPPVQ 606
Query: 576 VSIQAVNQPLMPLP--QTLSLYQDPLYPGFPCNEKGD 610
VS++ +P +T +L PL P P ++ D
Sbjct: 607 VSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD 643
Score = 31.6 bits (70), Expect = 4.1
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 16/141 (11%)
Query: 231 NGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKK----MKKPSTSG 286
N LN +V+ S+ G V ++E +KH K+LKA ++ K+ K+ TS
Sbjct: 464 NVTHLNTEVKN-SSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSE 522
Query: 287 QNFHSDVDYRGPKNPSKPIKAPSALPPRL-----------QHPSGVRQHAFSSHSSGSQS 335
+ + P P P P L Q P Q AFS + S S
Sbjct: 523 KETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTS 582
Query: 336 QKFSSEHKNLSRTPSQIIRKP 356
S H S SQ +P
Sbjct: 583 TLPPSTHSKTSAVSSQANSQP 603
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 43.9 bits (102), Expect = 8e-04
Identities = 80/337 (23%), Positives = 128/337 (37%), Gaps = 59/337 (17%)
Query: 302 SKPIKAPSALPPRLQHPSGVRQHAFSSHSSG-SQSQKFSSEHKNLSRTPSQIIRKPDRER 360
SK + S LP R S R A+S HSS S+ ++ SS ++ S +P +R P
Sbjct: 338 SKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP---VRLPLNS- 393
Query: 361 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 420
L E R+K+ + ++ ++ + P N S
Sbjct: 394 --------------SLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 421 NPCVQRKSSHVGDRKGSR--------RRMDTEERKDKDSIHGHSQLDKRPEPSTLENITD 472
+ +K + S ++TE + D+ G +LD+ E ++++
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDT--GKVKLDENSEKHLVKDLKA 497
Query: 473 DKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT-------------- 518
T S + K E +P E + +E + P P + SP L
Sbjct: 498 Q--GTRDSKPIALKEEIVTPKETETSEKET-PPPLPTIASPPPPLPTTTPPPQTPPLPPL 554
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTL---TTGPDSAVSQAHLTPSPVP 575
P +P+LP P PS+P + VPA S T TL T SAVS + PV
Sbjct: 555 PPIPALPQQPPLPPSQPAF---SQVPA-----SSTSTLPPSTHSKTSAVSSQANSQPPVQ 606
Query: 576 VSIQAVNQPLMPLP--QTLSLYQDPLYPGFPCNEKGD 610
VS++ +P +T +L PL P P ++ D
Sbjct: 607 VSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD 643
Score = 31.6 bits (70), Expect = 4.1
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 16/141 (11%)
Query: 231 NGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKK----MKKPSTSG 286
N LN +V+ S+ G V ++E +KH K+LKA ++ K+ K+ TS
Sbjct: 464 NVTHLNTEVKN-SSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSE 522
Query: 287 QNFHSDVDYRGPKNPSKPIKAPSALPPRL-----------QHPSGVRQHAFSSHSSGSQS 335
+ + P P P P L Q P Q AFS + S S
Sbjct: 523 KETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTS 582
Query: 336 QKFSSEHKNLSRTPSQIIRKP 356
S H S SQ +P
Sbjct: 583 TLPPSTHSKTSAVSSQANSQP 603
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/207 (26%), Positives = 73/207 (35%), Gaps = 54/207 (26%)
Query: 462 PEPSTLENITDDKYATVSSP-SKSKKLECPSPAEQKPAEHVSLSNPAPLLVS-------- 512
P P ++ + D S+P S S + P PA P+ V LS PAP +S
Sbjct: 260 PAPPSVPTLISD-----SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPL 314
Query: 513 -------------------PEVHLTPAVPSLPATVPAWPSEP-----------------T 536
P L P S P PA PS P
Sbjct: 315 ALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIP 374
Query: 537 TFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQ 596
F PT VPAP P T T P +A A T +P+P S ++++ P Q ++ +
Sbjct: 375 AFAPTPVPAPTPAPIFTPAPTPMP-AATPAAIPTSAPIPASF-SLSRVCFPAAQAPAMQK 432
Query: 597 DPL--YPGFPCNEKGDRAIVPPYSLCQ 621
PL PG +PP S Q
Sbjct: 433 VPLSFQPGTVLTPSQPLVYIPPPSCGQ 459
Score = 34.7 bits (78), Expect = 0.48
Identities = 114/509 (22%), Positives = 162/509 (31%), Gaps = 93/509 (18%)
Query: 492 PAEQKPAEHVSLSNPAPL----LVSPEVHLTPAVPS-----LPATVPAWPSEPTTF---G 539
P A V LS PAP+ LV +V + PS +PA PA PS PT
Sbjct: 214 PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSN 273
Query: 540 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 599
P V A + V +GP + P+P P+S+ P L+L Q P+
Sbjct: 274 PLSVSASVLVPVPASAPPSGPVPLSA-----PAPAPLSVPVSAPP-------LALIQAPV 321
Query: 600 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 659
P P A VP L P S PM P P
Sbjct: 322 PPSAPTLV---LAPVPTPVLAPMPASTPP----------AAPAPPSVPMPTPTPSSGPPS 368
Query: 660 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVN------GQ 713
L + PVP P F AP + P+ S++ Q
Sbjct: 369 TPTLIPA--FAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQ 426
Query: 714 MPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFP- 772
P + P +F V+ PSQ L Y P + +S P
Sbjct: 427 APAMQKVPLSFQPGTVLTPSQ------PLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
Query: 773 QPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLD 832
PS+ + L V +P YP+ + P L SD K + L + L
Sbjct: 481 LPSYLQDRCLPGVLASPEL-----RSYPYAFSVARP-------LTSDSK-LVSLEVNRLP 527
Query: 833 LSKDCGSVSTVDEFPEARGEHVHS----------------LPEASVSSKP------DEGR 870
+ GS +T G + LP S SS P G
Sbjct: 528 CTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGT 587
Query: 871 TEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVK 930
+Q+ T + L S P + A PP E +P++L K Q L ++
Sbjct: 588 EQQTEGTSVTFSPLKSPPQLEREMASPP------ECSEMPLDLSSKSNRQKLPLPNQRKT 641
Query: 931 DPKTAADVVSPGANSVDSRVQRPKEESSE 959
P V + ++ S V + +++
Sbjct: 642 PPMPVLTPVHTSSKALLSTVLSRSQRTTQ 670
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/196 (23%), Positives = 70/196 (35%), Gaps = 10/196 (5%)
Query: 403 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMD-TEERKDKDSIHGHSQLDKR 461
+ P S +S S + + V+ K + +++ S + T K+ SI S D
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 521
P L T T P+ + E P+P K + P P + TP
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIK-SAPTTPKE 246
Query: 522 PSLPATVPAWPSEPTTFGPTGV--PAPIPVLSVTQTLTTGPDSAVSQAHLT----PSPVP 575
P+ P T + P+ P PT PAP T T P +++ T P+P
Sbjct: 247 PA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305
Query: 576 VSIQAVNQPLMPLPQT 591
A P P P T
Sbjct: 306 PKKPAPTTPKEPAPTT 321
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 10/137 (7%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV--SPEVHL 517
K P P+T T T P+ + E P+P K + PAP +P
Sbjct: 245 KEPAPTT----TKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299
Query: 518 TPA--VPSLPA-TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 574
PA P PA T P P+ T PT P + + T P A P+P
Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359
Query: 575 PVSIQAVNQPLMPLPQT 591
A P P P T
Sbjct: 360 TPKEPAPTTPKEPAPTT 376
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%)
Query: 460 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 518
K P P+T E T K ++P K PA P E + P +P+
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 578
S P T T PT P P + TT P P+P
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 449
Query: 579 QAVNQPLMPLPQT 591
A P P P T
Sbjct: 450 PAPTTPKEPAPTT 462
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P P+T + +P+ K+ +P E P L+ P ++P P
Sbjct: 456 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 579
A + P P EPT PT P P T P +A P+P
Sbjct: 507 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 554
Query: 580 AVNQPLMPLPQT 591
A P P P T
Sbjct: 555 APTTPKEPAPTT 566
Score = 34.7 bits (78), Expect = 0.48
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
++P P+T E + T P+ + E P+P K A + PAP TP
Sbjct: 504 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T P S P+
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 616
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 617 PTTPKGTAPTTPKEPAPTT 635
Score = 34.3 bits (77), Expect = 0.63
Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T ++ T + A ++ S + PSP K + PAP
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 576
TP P+ P P EP PT P P TT ++A + LTP+ P
Sbjct: 446 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 496
Query: 577 SIQAVNQPLMPLPQT 591
+ A P P P T
Sbjct: 497 KL-APTTPEKPAPTT 510
Score = 33.9 bits (76), Expect = 0.82
Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P+TL K ++P K E +P K + PAP TP
Sbjct: 576 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 628
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T GP S S P+
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 685
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 686 PTTPKETAPTTPKEPAPTT 704
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T + T K ++P K E +P K + PAP
Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 695
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 576
TP P+ P+ P T PT P + T+ PD + + P+P +
Sbjct: 696 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 755
Query: 577 SIQAVNQPLMPLPQT 591
+ +P +P +T
Sbjct: 756 E-NSPKEPGVPTTKT 769
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/196 (23%), Positives = 70/196 (35%), Gaps = 10/196 (5%)
Query: 403 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMD-TEERKDKDSIHGHSQLDKR 461
+ P S +S S + + V+ K + +++ S + T K+ SI S D
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 462 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 521
P L T T P+ + E P+P K + P P + TP
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIK-SAPTTPKE 287
Query: 522 PSLPATVPAWPSEPTTFGPTGV--PAPIPVLSVTQTLTTGPDSAVSQAHLT----PSPVP 575
P+ P T + P+ P PT PAP T T P +++ T P+P
Sbjct: 288 PA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346
Query: 576 VSIQAVNQPLMPLPQT 591
A P P P T
Sbjct: 347 PKKPAPTTPKEPAPTT 362
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 10/137 (7%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV--SPEVHL 517
K P P+T T T P+ + E P+P K + PAP +P
Sbjct: 286 KEPAPTT----TKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340
Query: 518 TPA--VPSLPA-TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 574
PA P PA T P P+ T PT P + + T P A P+P
Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400
Query: 575 PVSIQAVNQPLMPLPQT 591
A P P P T
Sbjct: 401 TPKEPAPTTPKEPAPTT 417
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%)
Query: 460 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 518
K P P+T E T K ++P K PA P E + P +P+
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431
Query: 519 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 578
S P T T PT P P + TT P P+P
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 490
Query: 579 QAVNQPLMPLPQT 591
A P P P T
Sbjct: 491 PAPTTPKEPAPTT 503
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P P+T + +P+ K+ +P E P L+ P ++P P
Sbjct: 497 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 579
A + P P EPT PT P P T P +A P+P
Sbjct: 548 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 595
Query: 580 AVNQPLMPLPQT 591
A P P P T
Sbjct: 596 APTTPKEPAPTT 607
Score = 34.7 bits (78), Expect = 0.48
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
++P P+T E + T P+ + E P+P K A + PAP TP
Sbjct: 545 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T P S P+
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 657
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 658 PTTPKGTAPTTPKEPAPTT 676
Score = 34.3 bits (77), Expect = 0.63
Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T ++ T + A ++ S + PSP K + PAP
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 576
TP P+ P P EP PT P P TT ++A + LTP+ P
Sbjct: 487 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 537
Query: 577 SIQAVNQPLMPLPQT 591
+ A P P P T
Sbjct: 538 KL-APTTPEKPAPTT 551
Score = 33.9 bits (76), Expect = 0.82
Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%)
Query: 460 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 519
K P+TL K ++P K E +P K + PAP TP
Sbjct: 617 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 669
Query: 520 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 572
P+ P+ P PT + P P + T T GP S S P+
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 726
Query: 573 PVPVSIQAVNQPLMPLPQT 591
P A P P P T
Sbjct: 727 PTTPKETAPTTPKEPAPTT 745
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%)
Query: 460 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 517
K P P+T + T K ++P K E +P K + PAP
Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 736
Query: 518 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 576
TP P+ P+ P T PT P + T+ PD + + P+P +
Sbjct: 737 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 796
Query: 577 SIQAVNQPLMPLPQT 591
+ +P +P +T
Sbjct: 797 E-NSPKEPGVPTTKT 810
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 42.4 bits (98), Expect = 0.002
Identities = 148/663 (22%), Positives = 220/663 (33%), Gaps = 129/663 (19%)
Query: 437 SRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQK 496
+RRR + EER+ Q ++R + D+K+ +P K K E +P
Sbjct: 467 ARRRREEEERR--------MQEERRAACAEKLKRLDEKFG---APDKRLKAEPAAP---- 511
Query: 497 PAEHVSLSNPAPLLVSP-EVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQT 555
PA + S PAP P E+ PA P A P E P P P ++ T
Sbjct: 512 PA---APSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT 568
Query: 556 LTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVP 615
L +G S S + + PV Q P P+ P P P E I P
Sbjct: 569 LVSGGGSTSSTSSGSFEASPVEPQL---PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGP 625
Query: 616 PYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVP 675
G PK + L F + H + HQ A P PVP
Sbjct: 626 TRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ--WQQHQQGSA-----PPTPVP 678
Query: 676 VYPHNP-WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSP--LVIP- 731
P P PA Q P +A G + +P PP P ++IP
Sbjct: 679 PSPPQPVTLGAVPAPQAP----------PPPPKALYPGALGRPPPMPPMNFDPRWMMIPP 728
Query: 732 --------------------------PSQVSESHGQLSYQADLESETPGQLLH-----AD 760
P + S+S G S D P L D
Sbjct: 729 YVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFD--RHAPAMLRERGTPPVD 786
Query: 761 YEESLSGKNMFPQPSFGPNPFLGPV---------------PIAPPFFPHV--WYGYPFQG 803
+ + G ++F P P P+ P PP P++ + G+P G
Sbjct: 787 PKLAWVG-DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845
Query: 804 FIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVS 863
P+ R P +E G L S + + T E E L
Sbjct: 846 APGPPISR----FPLEEPGPRPLPWP--PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAG 899
Query: 864 SKPDEG-----------RTEQSSQTR---KADTALASIPPVAEGKAHPPTQILNRERETV 909
KP G R E ++TR + ++ IPP G PP + ++
Sbjct: 900 RKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGA--PPRRAGPIKKPPP 957
Query: 910 PVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILR 969
P ++E + + L++ E K PK ++ G ++ PKE + LR
Sbjct: 958 PTKVE-ELPPKPLEQGDETPKPPKPDPLKITKG------KLGGPKETPPNGNLSPAPRLR 1010
Query: 970 SGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRP 1029
S + T + + ++ GRG R +G+ +RSR+ ++ +R RG
Sbjct: 1011 RDYSYERVGPTSCRGRGRGEYFARGRG----FRGTYGGRGRGARSRE--FRSYREFRGDD 1064
Query: 1030 FRG 1032
RG
Sbjct: 1065 GRG 1067
Score = 31.2 bits (69), Expect = 5.3
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 268 PESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPS--GVRQHA 325
P+S N SG + +PS+SGQ + +V Y G PS + A+ +L HP+ G R
Sbjct: 1811 PQSKNLDSGHCVPEPSSSGQRLYPEVFY-GSAGPSSSQISGGAMDSQL-HPNSGGFRPGT 1868
Query: 326 FSSHSSGSQ 334
S H SQ
Sbjct: 1869 PSLHPYRSQ 1877
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%)
Query: 409 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 460
SS V Q A + VQ +S H D +G +E K+ S+ K
Sbjct: 626 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 678
Query: 461 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 516
+ +P+T L+ + ++Y + P ++ PSP + A+ P +P V
Sbjct: 679 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 738
Query: 517 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 560
TP V PSL P +P PS P P V P P L T L
Sbjct: 739 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 798
Query: 561 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 604
SA P P P+S PL L T+S P+ P P
Sbjct: 799 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 838
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%)
Query: 409 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 460
SS V Q A + VQ +S H D +G +E K+ S+ K
Sbjct: 827 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 879
Query: 461 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 516
+ +P+T L+ + ++Y + P ++ PSP + A+ P +P V
Sbjct: 880 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 939
Query: 517 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 560
TP V PSL P +P PS P P V P P L T L
Sbjct: 940 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 999
Query: 561 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 604
SA P P P+S PL L T+S P+ P P
Sbjct: 1000 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%)
Query: 409 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 460
SS V Q A + VQ +S H D +G +E K+ S+ K
Sbjct: 827 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 879
Query: 461 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 516
+ +P+T L+ + ++Y + P ++ PSP + A+ P +P V
Sbjct: 880 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 939
Query: 517 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 560
TP V PSL P +P PS P P V P P L T L
Sbjct: 940 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 999
Query: 561 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 604
SA P P P+S PL L T+S P+ P P
Sbjct: 1000 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 42.4 bits (98), Expect = 0.002
Identities = 63/253 (24%), Positives = 85/253 (33%), Gaps = 43/253 (16%)
Query: 481 PSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGP 540
P+ + PA P+ + P PL + H+T P P P P P P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP---PPPPPIPAPLPP 775
Query: 541 TGVPAP-IPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 599
P P + + + T T T P V+QA P+P P A QP P + Y P
Sbjct: 776 QAPPKPLVTIPAPTSTKTVAP--VVTQA-APPTPTPPVPPAKKQPAFP-----ASYIPPS 827
Query: 600 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 659
P P VPP LPK ++ C P S L P+
Sbjct: 828 PPTPP-------VPVPP-------PTLPKQQSF-------------CAK-PPPSPLSPVP 859
Query: 660 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 719
+P P P + + PA A P +S+ +P P+
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK-PKWQPSSI--PVPSPDF 916
Query: 720 GPPTFSSPLVIPP 732
PP S LV PP
Sbjct: 917 PPPPPESSLVFPP 929
Score = 37.4 bits (85), Expect = 0.075
Identities = 50/195 (25%), Positives = 73/195 (37%), Gaps = 7/195 (3%)
Query: 395 EIQNRDEQAFP--ALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSI 452
E R E A+ +LSSSS+ +S SS P Q S+ D S + R
Sbjct: 515 EALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVS 574
Query: 453 HGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVS 512
S+ KR + LE + + +++ P S L P + K + S P+P L
Sbjct: 575 SVFSEAWKRG--TQLEESSKARMESMNRPYTS--LVPPLSPQPKIVTPYTASQPSPPLPP 630
Query: 513 PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPS 572
P P P P P PS+ + P + ++T+ S TP
Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP- 689
Query: 573 PVPVSIQAVNQPLMP 587
PV S Q L+P
Sbjct: 690 PVMQSQSVKPQILVP 704
Score = 37.0 bits (84), Expect = 0.097
Identities = 41/167 (24%), Positives = 62/167 (37%), Gaps = 22/167 (13%)
Query: 457 QLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNP------APLL 510
Q P P + + +P + P P + P V++ P AP +
Sbjct: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP-V 797
Query: 511 VSPEVHLTPAVPSLPA-TVPAWPSE--PTTFGPTGVPAPIPVLSVTQTLTTGP------- 560
V+ TP P PA PA+P+ P + VP P P L Q+ P
Sbjct: 798 VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Query: 561 -DSAVSQ--AHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 604
S V Q + P P P +++ +QPL P+P ++ P P
Sbjct: 858 VPSVVKQIASQFPPPPTPPAME--SQPLKPVPANVAPQSPPAVKAKP 902
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,479,462
Number of Sequences: 37866
Number of extensions: 2632871
Number of successful extensions: 11662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 534
Number of HSP's that attempted gapping in prelim test: 9650
Number of HSP's gapped (non-prelim): 2328
length of query: 1048
length of database: 18,247,518
effective HSP length: 113
effective length of query: 935
effective length of database: 13,968,660
effective search space: 13060697100
effective search space used: 13060697100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.