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Search of human proteins with 40548372
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens]
(735 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens] 1472 0.0
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 57 5e-08
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 57 6e-08
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 55 3e-07
gi|150418009 transforming, acidic coiled-coil containing protein... 54 4e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 54 7e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 52 2e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 52 2e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 52 2e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 52 2e-06
gi|71043876 undifferentiated embryonic cell transcription factor... 51 3e-06
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 51 3e-06
gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens] 50 6e-06
gi|146134388 YLP motif containing 1 [Homo sapiens] 50 7e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 50 1e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 50 1e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 50 1e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 50 1e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 49 1e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 49 1e-05
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 49 2e-05
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 49 2e-05
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 49 2e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 2e-05
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 49 2e-05
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 48 3e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra... 48 3e-05
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 48 3e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 48 3e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 48 3e-05
>gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens]
Length = 735
Score = 1472 bits (3811), Expect = 0.0
Identities = 735/735 (100%), Positives = 735/735 (100%)
Query: 1 MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLAD 60
MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLAD
Sbjct: 1 MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLAD 60
Query: 61 KLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP 120
KLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP
Sbjct: 61 KLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP 120
Query: 121 EDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMV 180
EDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMV
Sbjct: 121 EDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMV 180
Query: 181 KSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA 240
KSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA
Sbjct: 181 KSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA 240
Query: 241 GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALSM 300
GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALSM
Sbjct: 241 GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALSM 300
Query: 301 SEMDRRNDAWLPGEATRGVLRAVATQQRGAVFVDKENLTMPGLRFDNIQGDAVKDLMLRF 360
SEMDRRNDAWLPGEATRGVLRAVATQQRGAVFVDKENLTMPGLRFDNIQGDAVKDLMLRF
Sbjct: 301 SEMDRRNDAWLPGEATRGVLRAVATQQRGAVFVDKENLTMPGLRFDNIQGDAVKDLMLRF 360
Query: 361 LGEKAAAKRQVLNADSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLLTSH 420
LGEKAAAKRQVLNADSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLLTSH
Sbjct: 361 LGEKAAAKRQVLNADSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLLTSH 420
Query: 421 TTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSM 480
TTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSM
Sbjct: 421 TTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSM 480
Query: 481 RILHAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLW 540
RILHAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLW
Sbjct: 481 RILHAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLW 540
Query: 541 RSRLGRVMYSMANCLLLMKDYVLAVEAYHSVIKYYPEQEPQLLSGIGRISLQIGDIKTAE 600
RSRLGRVMYSMANCLLLMKDYVLAVEAYHSVIKYYPEQEPQLLSGIGRISLQIGDIKTAE
Sbjct: 541 RSRLGRVMYSMANCLLLMKDYVLAVEAYHSVIKYYPEQEPQLLSGIGRISLQIGDIKTAE 600
Query: 601 KYFQDVEKVTQKLDGLQGKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNA 660
KYFQDVEKVTQKLDGLQGKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNA
Sbjct: 601 KYFQDVEKVTQKLDGLQGKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNA 660
Query: 661 AVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVA 720
AVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVA
Sbjct: 661 AVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVA 720
Query: 721 GKEGDSFNTQCLKLA 735
GKEGDSFNTQCLKLA
Sbjct: 721 GKEGDSFNTQCLKLA 735
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 57.4 bits (137), Expect = 5e-08
Identities = 67/224 (29%), Positives = 79/224 (35%), Gaps = 42/224 (18%)
Query: 73 SDSPNSE-GDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGE--ADGDCAPEDAA--PS 126
+D P G G+ G V ++ EPG G+PG P G P P GE G+ P AA P
Sbjct: 1265 ADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324
Query: 127 SGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPA-SGDGFEPQMVKSPSF 185
G P D + PG + PP EP P Q PP GD EP SP
Sbjct: 1325 PKGPPGDDGPKGSPGPVGFPGDPGPP-GEPGPA----GQDGPPGDKGDDGEPGQTGSPGP 1379
Query: 186 GGASEASA----RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAG 241
G S R PP P G+ A + PG
Sbjct: 1380 TGEPGPSGPPGKRGPPGPAGPEGRQ----GEKGAKGEAGLE-------------GPPGKT 1422
Query: 242 SP-----APASPPPLAVPGTEGRPEPVAMRG-PQAAAPPASPEP 279
P AP P P G G P PV +G P + P P P
Sbjct: 1423 GPIGPQGAPGKPGP---DGLRGIPGPVGEQGLPGSPGPDGPPGP 1463
Score = 47.4 bits (111), Expect = 5e-05
Identities = 75/289 (25%), Positives = 86/289 (29%), Gaps = 53/289 (18%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
GE P E HP PP EQGL +E G + L K
Sbjct: 1006 GETGPMGERGHPGPPGPPGEQGL-----------PGLAGKEGTKGDPGPAGLPGK----- 1049
Query: 67 MESVLISDSP----NSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAP- 120
D P GD G G V G EG PGP PAG+P G A G P
Sbjct: 1050 -------DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPA-GAAGPI 1101
Query: 121 -EDAAPSSGGAPRQDAAREVPGSE-----AARPEQEPPVAEPVPVCTIFSQRAPPASGDG 174
P G P + PG + A R + PV P P + G+
Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161
Query: 175 FEPQMVKSPSFGGASEASARTPPQ--VVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF 232
EP S G T PQ + QP PS + L D
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD------- 1214
Query: 233 ISVSNPGAGSPAPASPPPL----AVPGTEGRPEPVAMRGPQAAAPPASP 277
G P P P L PG +G V GP P P
Sbjct: 1215 ----EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGP 1259
Score = 40.8 bits (94), Expect = 0.005
Identities = 51/213 (23%), Positives = 65/213 (30%), Gaps = 21/213 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAP----SSGGAP 131
P G G G D+ EPG G PG P G P PSG P A P GA
Sbjct: 1353 PGPAGQDGPPGDKGDDGEPGQTGSPG--PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVP------VCTIFSQRAPPASGDGFEPQMVKSPSF 185
+ PG Q P +P P + Q P + G P + P
Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAP-GKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGL 1469
Query: 186 GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAP 245
G S P+ + P L G S S P
Sbjct: 1470 PGLKGDSG---PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS-----SGPKGEQGIT 1521
Query: 246 ASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P+ PG G P P +G + ++ P P+
Sbjct: 1522 GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPK 1554
Score = 38.1 bits (87), Expect = 0.029
Identities = 73/294 (24%), Positives = 102/294 (34%), Gaps = 79/294 (26%)
Query: 3 DAGGGEETPAPEAP--HPPQLAPPEEQGL-----LFQEETI-DLGGDEFGSEENETASEG 54
D G G E P A + APP +G F EETI +L + + + T+S
Sbjct: 369 DPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPS 428
Query: 55 SSPLADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEA--EPGG--EGDPGPE-PAGTPS 109
N+ + + G G+ G+ + A EPG EG PGPE PAG P
Sbjct: 429 EIGPGMPANQDTIYEGI-------GGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG 481
Query: 110 PSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPP 169
P G D P G P + PG P A+ +P PP
Sbjct: 482 PPGTMGPTGQVGD--PGERGPPGR------PGL---------PGADGLP--------GPP 516
Query: 170 ASGDGFEPQMVKSP-SFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFT 228
+ M+ P FGG +A ++ P Q S + +
Sbjct: 517 GT-------MLMLPFRFGGGGDAGSKGPMVSAQESQA-------------------QAIL 550
Query: 229 TSAFISVSNPGA-----GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
A +++ P G P P PP G +G P V +GP+ P P
Sbjct: 551 QQARLALRGPAGPMGLTGRPGPVGPPGSG--GLKGEPGDVGPQGPRGVQGPPGP 602
Score = 36.2 bits (82), Expect = 0.11
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGD 117
P ++G G G+ E GG+G PGP+ P G P P G D
Sbjct: 756 PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798
Score = 35.0 bits (79), Expect = 0.25
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 16/100 (16%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGE-----ADGDCAPE-- 121
S P GD G+ G + G G+PGP P G P P G DG P+
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710
Query: 122 ---DAAPSSGGAPRQDAAREVPGSEAA--RPEQEPPVAEP 156
P G A+ +PG + A P ++ P+ +P
Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKP 750
Score = 34.3 bits (77), Expect = 0.43
Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 15/118 (12%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEA--DGDCAPEDAAPSSGGAPRQDA 135
+GD G G E G GDPGP P G P GE DG+ P G P +
Sbjct: 627 KGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR-------GLPGEPG 679
Query: 136 AREVPGSEAARPEQEPP-----VAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGA 188
R + G + PP +P P + Q P G P P GA
Sbjct: 680 PRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737
Score = 33.9 bits (76), Expect = 0.56
Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 5/82 (6%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPA-GTPSPSGEADGDCAPEDAAPSSGGAPRQDAARE 138
G G+ G + PG +G PGP+ A G P G P P + G P
Sbjct: 712 GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLP--GMPGADGPPGHPGKEG 769
Query: 139 VPGSEAAR--PEQEPPVAEPVP 158
PG + + P + P+ P P
Sbjct: 770 PPGEKGGQGPPGPQGPIGYPGP 791
Score = 33.5 bits (75), Expect = 0.73
Identities = 42/164 (25%), Positives = 61/164 (37%), Gaps = 29/164 (17%)
Query: 10 TPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHMMES 69
+P P+ P P + PP GL GD S P +K + ++
Sbjct: 1454 SPGPDGP-PGPMGPPGLPGLK---------GD-------------SGPKGEKGHPGLIGL 1490
Query: 70 VLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSG 128
+ +GD G G G +G GP P G P P G G P+ A SSG
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG-LPGPPGPKGAKGSSG 1549
Query: 129 -GAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPAS 171
P+ +A P P + V +P+P+ ++R AS
Sbjct: 1550 PTGPKGEAGHPGPPGPPGPPGE---VIQPLPIQASRTRRNIDAS 1590
Score = 32.0 bits (71), Expect = 2.1
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCA---PEDAAPSSGGAPR 132
P S G G+ G V + G +G PG PAG P G A D A P P G
Sbjct: 576 PGSGGLKGEPGDVGPQGPRGVQGPPG--PAGKPGRRGRAGSDGARGMPGQTGPK--GDRG 631
Query: 133 QDAAREVPGSEAARPEQEP 151
D +PG + R + P
Sbjct: 632 FDGLAGLPGEKGHRGDPGP 650
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 12/77 (15%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P +GD G G + PG G+ GPE P G P+G+ P G P +
Sbjct: 816 PGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD-----------PGPLGPPGEK 864
Query: 135 AAREVPGSEAARPEQEP 151
VPG Q P
Sbjct: 865 GKLGVPGLPGYPGRQGP 881
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 57.0 bits (136), Expect = 6e-08
Identities = 68/290 (23%), Positives = 94/290 (32%), Gaps = 51/290 (17%)
Query: 11 PAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSP-LADKLNEHMMES 69
P P AP PP + L + +E G + +S ++P LA+ + +
Sbjct: 293 PGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRV 352
Query: 70 VLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG----------PEPAGTPSPSGEADGDCA 119
S D G+ EA P G P PE +P P+ +GD
Sbjct: 353 EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTT 412
Query: 120 PEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQM 179
P + P+ A E P + P AEP P ++ PP E +
Sbjct: 413 PPETDPA--------ATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREA 464
Query: 180 VKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG 239
P E A T P+ + PS + A L P
Sbjct: 465 ETEP------ERGAGTEPERIGTEPSTAPAPSPPAPKSCLK---------------HRPA 503
Query: 240 AGSPAPASPPPLAV---PGTEGRP--------EPVAMRGPQAAAPPASPE 278
A S PA+ PPLA P E P P + +A APPA E
Sbjct: 504 AASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAE 553
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 54.7 bits (130), Expect = 3e-07
Identities = 67/247 (27%), Positives = 91/247 (36%), Gaps = 39/247 (15%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAARE 138
+GD G +G EPG G PGP G P G+ G P+ SSG +E
Sbjct: 434 KGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSG-----IPGKE 488
Query: 139 VPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGG-----ASEASA 193
PG + +P + +P VC P +GF+ V P G A
Sbjct: 489 GPGGKPGKPGVKGEKGDPCEVC--------PTLPEGFQ-NFVGLPGKPGPKGEPGDPVPA 539
Query: 194 RTPPQVV-------QPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPA 246
R P + +P S S+ G A H ++S T A V +PG G P
Sbjct: 540 RGDPGIQGIKGEKGEPCLSCSSVVG---AQHLVSS-------TGASGDVGSPGFG--LPG 587
Query: 247 SPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALSMSEMDRR 306
P VPG +G GP + P P A I+ +P ++ + D R
Sbjct: 588 LPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVR 647
Query: 307 NDAWLPG 313
A LPG
Sbjct: 648 VVA-LPG 653
Score = 38.9 bits (89), Expect = 0.017
Identities = 59/217 (27%), Positives = 71/217 (32%), Gaps = 53/217 (24%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEAD-GDCAPEDAAPSSGGA 130
P +G+ G G D+ EPG G PG P G P GE A E P G
Sbjct: 1065 PGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP---GP 1121
Query: 131 PRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGD-GFEPQMVKSPSFGGAS 189
P + PG R E+ P Q GD GF+ Q P F G
Sbjct: 1122 PGSEGLPGPPGPAGPRGERGP-------------QGNSGEKGDQGFQGQ----PGFPG-P 1163
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA--GSPAPAS 247
P +V P P G A S + P GSP P
Sbjct: 1164 PGPPGFPGKVGSPGPP-----GPQAEKGS--------------EGIRGPSGLPGSPGPPG 1204
Query: 248 PP----PLAVPGTEGRPEPVAMRG-PQAAAPPASPEP 279
PP P + G +G+ +RG P A PP P
Sbjct: 1205 PPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGP 1241
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 3/86 (3%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGP-EPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P +GD G G PG EG+PG P G P P G P P+ A
Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLK 1313
Query: 135 AAREVPGSE--AARPEQEPPVAEPVP 158
R G A P Q P P P
Sbjct: 1314 GDRGATGERGLAGLPGQPGPPGHPGP 1339
Score = 37.7 bits (86), Expect = 0.038
Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 12/86 (13%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGE--ADGDCAPE-------DAAP 125
P +G AG+ G + + G GDPG P G P SGE G P+ A P
Sbjct: 669 PGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACP 728
Query: 126 SSGGAPRQDAAREVPGSEAARPEQEP 151
S G A R PG + EQ P
Sbjct: 729 SLQGTVTDMAGR--PGQPGPKGEQGP 752
Score = 37.7 bits (86), Expect = 0.038
Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 34/147 (23%)
Query: 79 EGDAGDLGR--VRDEAEPGGEGDPG----PEPAGTPSPSGE-----------ADGDCAPE 121
+G+ G GR + EPG G PG P P G P P+GE A G P
Sbjct: 779 QGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPP 838
Query: 122 DAA----PSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEP 177
A+ P G Q R PG + R E+ P + + P+ GD
Sbjct: 839 GASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEP-----------GECSCPSQGDLIFS 887
Query: 178 QMVKSPS--FGGASEASARTPPQVVQP 202
M +P G + + + PP + P
Sbjct: 888 GMPGAPGLWMGSSWQPGPQGPPGIPGP 914
Score = 33.5 bits (75), Expect = 0.73
Identities = 31/97 (31%), Positives = 37/97 (38%), Gaps = 18/97 (18%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSG-----------EADGDCAPEDA 123
P +G AG G + +PG GDPGP P G P G GDC +
Sbjct: 1206 PGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCG-KPG 1264
Query: 124 APSSGGAPRQDAAREVPGSEAARPEQEPP--VAEPVP 158
P S G P A PG+ + PP V P P
Sbjct: 1265 PPGSTGRP---GAEGEPGAMGPQGRPGPPGHVGPPGP 1298
Score = 32.7 bits (73), Expect = 1.2
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP-EDAAPSSGGAP 131
+G AG+ GR PG G G P G P P+GE AP +P G P
Sbjct: 1376 KGQAGEKGRAGMPGGPGKSGSMG--PVGPPGPAGERGHPGAPGPSGSPGLPGVP 1427
Score = 31.2 bits (69), Expect = 3.6
Identities = 59/221 (26%), Positives = 69/221 (31%), Gaps = 34/221 (15%)
Query: 78 SEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADGDCAP-------EDAAPS 126
S G+ G+ G E PG G GP P G G+ P P
Sbjct: 1112 SAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPG 1171
Query: 127 SGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG 186
G+P + GSE R P P P Q PA DG + + K G
Sbjct: 1172 KVGSPGPPGPQAEKGSEGIRGPSGLP-GSPGPPGPPGIQ--GPAGLDGLDGKDGKPGLRG 1228
Query: 187 GASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA-GSPAP 245
A PP ++ P F L D S PGA G P
Sbjct: 1229 DPGPAG---PPGLMGPPG-----FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGA 1280
Query: 246 ASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAV 286
P +GRP P GP PP P P A I AV
Sbjct: 1281 MGP--------QGRPGPPGHVGP--PGPPGQPGP-AGISAV 1310
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 6/86 (6%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P G+ G G E PG +G GP P G P +G+ G + A GG +
Sbjct: 1337 PGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQ-KGQAGEKGRAGMPGGPGKSG 1395
Query: 135 AAREV----PGSEAARPEQEPPVAEP 156
+ V P E P P P
Sbjct: 1396 SMGPVGPPGPAGERGHPGAPGPSGSP 1421
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 54.3 bits (129), Expect = 4e-07
Identities = 50/176 (28%), Positives = 69/176 (39%), Gaps = 21/176 (11%)
Query: 4 AGGGEETPAPEAPHPPQLAPPEEQG-----LLFQEETIDLGGDEFGSEENETASEGSSPL 58
AGG E P +P P L P EE F I + +E GS E+ S+ P+
Sbjct: 393 AGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPV 452
Query: 59 ADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDC 118
+ + ++++ L+ E DLG + EGDPG PA +P GE
Sbjct: 453 SADAAKEVVDAGLV----GLERQVSDLGSKGEHP----EGDPGEVPAPSPQERGEHLNTE 504
Query: 119 APEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDG 174
+ P G P +E S +P PP P+P S R PP DG
Sbjct: 505 QSHEVQP---GVPPPPLPKE--QSHEVQPGAPPP---PLPKAPSESARGPPGPTDG 552
Score = 37.4 bits (85), Expect = 0.050
Identities = 74/313 (23%), Positives = 103/313 (32%), Gaps = 78/313 (24%)
Query: 8 EETPAPEAPHPPQ------LAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK 61
+E P PE P P +PPE +ET D EE T E P
Sbjct: 1776 KEQPGPERPIPAGDGKVCVSSPPEP------DETHDPKLQHLAPEELHTDRESPRP---- 1825
Query: 62 LNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEG-DPGPEPAGTPSPSGEADGDCAP 120
M+ SV D+P + +V + G EG + P P+ AD + +P
Sbjct: 1826 -GPSMLPSVPKKDAPRV------MDKVTSDETRGAEGTESSPVADDIIQPAAPADLE-SP 1877
Query: 121 EDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEP--- 177
AA S G V V I +P A+ G P
Sbjct: 1878 TLAASSYHG----------------------DVVGQVSTDLIAQSISPAAAHAGLPPSAA 1915
Query: 178 QMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSN 237
+ + SPS A TP D A S +SD ++F T +
Sbjct: 1916 EHIVSPSAPAGDRVEASTPS------------CPDPAKDLSRSSDSEEAFETP---ESTT 1960
Query: 238 PGAGSPAPASPPPLAVPGTEGRPEPVAMR------------GPQAAAPPASP-EPFAHIQ 284
P PAP PPP +P E +P GP++ + SP P +H
Sbjct: 1961 PVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSF 2020
Query: 285 AVFAGSDDPFATA 297
+ D P A++
Sbjct: 2021 SAVFDEDKPIASS 2033
Score = 30.8 bits (68), Expect = 4.7
Identities = 52/216 (24%), Positives = 79/216 (36%), Gaps = 25/216 (11%)
Query: 2 EDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK 61
+ GG EE P P P E+ + ++G DE S+ + A P +
Sbjct: 574 DSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDEL-SKPSSDAESRDHPSSHS 632
Query: 62 LNEHMMESVLISDSPNS---EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPS-PSG---EA 114
+D P+S E DA L E +P P P+ AG P+ P G E
Sbjct: 633 AQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDP--VLPPVPDGAGEPTVPEGAIWEG 690
Query: 115 DGDCAPE--DAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVC-----TIFSQRA 167
G P+ D S G R ++ + ++ P PVAE P T+ ++
Sbjct: 691 SG-LQPKCPDTLQSREGLGRMESFLTLESEKSDFP--PTPVAEVAPKAQEGESTLEIRKM 747
Query: 168 PPASGDGF--EPQMVKSPSFGGASE---ASARTPPQ 198
G+G P + P+ + + A PPQ
Sbjct: 748 GSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQ 783
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 53.5 bits (127), Expect = 7e-07
Identities = 60/197 (30%), Positives = 70/197 (35%), Gaps = 38/197 (19%)
Query: 92 AEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEP 151
A P +G P P A PSP G A PS AP AA P S P
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGP--------ATPSPKWAPTPPAA--TPPSPKGGPATPS 981
Query: 152 PVAEPVP-VCTIFSQRAPPASGD---GFEPQMVKSPSFGGASEAS-----ARTPPQVVQP 202
P P P T S + PA+ P V PS G+ A+ A TPP P
Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 203 SPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEP 262
SP G AA T + + P A P+P P A P +G P P
Sbjct: 1042 SPK-----GSPAA------------TPLPKGAPTTPAATLPSPKGGP--ATPSLKGAPTP 1082
Query: 263 VAMRGPQAAAPPASPEP 279
A P PA+P P
Sbjct: 1083 PAATPPSPKGGPATPSP 1099
Score = 48.9 bits (115), Expect = 2e-05
Identities = 70/282 (24%), Positives = 98/282 (34%), Gaps = 52/282 (18%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK--L 62
GG TP+P+ AP PP PP +G G + + ++P + K L
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKG-----------GLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 63 NEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPED 122
+ + + G L A P +G P A PSP G
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGL------ATPPPKGAPTTPAATPPSPKGGL-------- 1186
Query: 123 AAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFE-PQMVK 181
A PS GAP AA P + P A P T PP+ G P
Sbjct: 1187 ATPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAAT------PPSPKGGLATPSPKG 1239
Query: 182 SPSFGGASEASAR----TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSN 237
+P+ A+ S + TPP P+P +T + LA+ A ++ +
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAAT---PPSLKGGLATPPHKGAPNPAVVTPPS 1296
Query: 238 PGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
P G PA+ PP +G P P A P P +P P
Sbjct: 1297 PKGG---PATSPP------KGAPTPPAATPPSPKGSPGTPPP 1329
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/295 (24%), Positives = 100/295 (33%), Gaps = 46/295 (15%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK--L 62
GG TP+ + AP PP PP + GG S + ++P + K L
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPK-----------GGPATPSPKGAPMPPAATPPSPKGGL 1117
Query: 63 NEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAG---TPSPSGEADGDCA 119
+ + + G L + P P P G TP P G A
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 120 PED------AAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGD 173
A PS GAP AA P + P A P T PP+
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAAT------PPSPKG 1230
Query: 174 GF-EPQMVKSPSFGGASEASAR----TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFT 228
G P +P+ A+ S + TPP P+P +T + LA+
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT---PPSLKGGLATPPHKGAP 1287
Query: 229 TSAFISVSNPGAG---SPAPASP-PPLAVP----GTEGRPEPVAMRGPQAAAPPA 275
A ++ +P G SP +P PP A P G+ G P P P A PP+
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Score = 48.1 bits (113), Expect = 3e-05
Identities = 82/322 (25%), Positives = 113/322 (35%), Gaps = 61/322 (18%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNE 64
GG TP+P+ AP PP + PP +G T G + +GS P A L +
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGS-PAATPLPK 1054
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEP--------GGEGDPGPE-----PAGTPSPS 111
+ + P+ +G P GG P P+ PA TP PS
Sbjct: 1055 GA-PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-PS 1112
Query: 112 GEADGDCAPEDAAPSSGGA----PRQDAAREVPGSEAARPEQEPP-----VAEPVPVCTI 162
+ P AP++ A P+ A P P PP +A P P
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 163 FSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQ----VVQPSPSLSTFFGDTAASHS 218
+ A P S G + +PS GA A TPP + PSP + T + +
Sbjct: 1173 TTPAATPPSPKGG----LATPSPKGAPTTPAATPPSPKGGLATPSPKGAP----TTPAAT 1224
Query: 219 LASDFFDSFTTSAFISVSNPGAGSPAP----ASPPP-----------------LAVPGTE 257
S T S + + P A P+P A+PPP LA P +
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 258 GRPEPVAMRGPQAAAPPASPEP 279
G P P + P PA+ P
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPP 1306
Score = 45.4 bits (106), Expect = 2e-04
Identities = 75/314 (23%), Positives = 106/314 (33%), Gaps = 52/314 (16%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNE 64
GG TP P+ AP PP PP +G L + + +SP
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA--- 1309
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAA 124
+ + P+ +G G P +G P P PSP G
Sbjct: 1310 ---PTPPAATPPSPKGSPGT---------PPPKGAPTPPAVTPPSPKGTPTLPAT----T 1353
Query: 125 PSSGGAPRQDAAREVPGSEAARPEQE--PPVAEPVPVCTIFSQRAPPASGDGFEPQMV-- 180
PSS G P +++E P AA P + P + P P P GD P ++
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK---RGPAIPSPKGDPTSPAVIPL 1410
Query: 181 ---KSPSFGGASEASAR------TPPQV----VQPSPSLSTFFGDTAASHSLASDFFDSF 227
K+P+ E +A TPP V ++ +P+ S G A S +
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 228 TTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQ-AAAPPASPEPFAHIQAV 286
T S P A S P P T P M P A P+SP+ + A
Sbjct: 1471 TPP---SPKEPPAPKQVATSSSPKKAPAT-----PAPMGAPTLPAVIPSSPK---EVPAT 1519
Query: 287 FAGSDDPFATALSM 300
+ DP A ++
Sbjct: 1520 PSSRRDPIAPTATL 1533
Score = 45.4 bits (106), Expect = 2e-04
Identities = 67/306 (21%), Positives = 103/306 (33%), Gaps = 62/306 (20%)
Query: 6 GGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK---- 61
GG TP+ + P A P +G G S + + S PL+ K
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 62 ---------------LNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG----- 101
L + V + +P + G A P +GDP
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG------PATPSSKGDPTLPAVT 1471
Query: 102 -PEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQDAA-----REVPGSEAARPEQEPPVA 154
P P P+P A + A P+ GAP A +EVP + ++R + P+A
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD---PIA 1528
Query: 155 EPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTA 214
P T+ S++ P + A PP + PSP +
Sbjct: 1529 ---PTATLLSKKTPAT-----------------LAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 215 ASHSLASDFFDSFTTSAFISVSNPGAGSPAPAS-PPPLAVPGTEGRPEPVAMRGPQAAAP 273
+ + S ++ + A + GA SP PP + P + P P A+ P
Sbjct: 1569 EAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 274 PASPEP 279
PA+P P
Sbjct: 1628 PATPAP 1633
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/305 (25%), Positives = 109/305 (35%), Gaps = 47/305 (15%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNE 64
G TP P+ AP PP + PP +G T G ++ EG +P A
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP---SSKGGPTTPSSKEGPTPPA-ATPS 1377
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTP-SPSGEADGDCAPEDA 123
H + SP R A P +GDP PA P SP E A
Sbjct: 1378 HKGGPAMTPPSPK-----------RGPAIPSPKGDP-TSPAVIPLSPKKAPATPVTREGA 1425
Query: 124 APSSGG-----APRQDAAREVPGSEAARPEQEPPVAE---PVPVCTIFSQRAPPASGDGF 175
A S G A + ++ P + A + P ++ +P T S + PPA
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA----- 1480
Query: 176 EPQMV---KSPSFGGASEA--SARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTS 230
P+ V SP A+ A A T P V+ SP + A+ S D T+
Sbjct: 1481 -PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK------EVPATPSSRRD--PIAPTA 1531
Query: 231 AFISVSNPGAGSPAPA-SPPPLAVPGTEGRPE-PVAMRGPQAAAPPASPEPFAHIQAVFA 288
+S P +P A PP + VP + P P P + + P A + +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 289 GSDDP 293
G+ P
Sbjct: 1592 GAPSP 1596
Score = 43.9 bits (102), Expect = 5e-04
Identities = 72/296 (24%), Positives = 90/296 (30%), Gaps = 55/296 (18%)
Query: 6 GGEETPAPE-APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADK--L 62
GG TP P+ AP P PP +G G + + ++P + K L
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKG-----------GLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 63 NEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAG---TPSPSGEADGDCA 119
+ + + G L + P P P G TPSP G
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG---APTT 1243
Query: 120 PEDAAPSSGGAPRQDAAREVPGSEAARPEQ-------EPPVAEPVP-VCTIFSQRAPPAS 171
P PS G P + P AA P P P P V T S + PA+
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 172 G---DGFEPQMVKSPSFGGA----SEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFF 224
P PS G+ A TPP V PSP + T S
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS-------- 1355
Query: 225 DSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRP---EPVAMRGPQAAAPPASP 277
S P S PP A P +G P P RGP +P P
Sbjct: 1356 ---------SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Score = 39.7 bits (91), Expect = 0.010
Identities = 72/310 (23%), Positives = 102/310 (32%), Gaps = 67/310 (21%)
Query: 12 APEAPH-------PPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNE 64
APE P PP PP + + T L +E T G+S A
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGT-PSPSGEADGDCAPED 122
++DSP+ G + + + P +G GP+ P G SP + PE+
Sbjct: 787 ----LTYLADSPSPLGVSVS---PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839
Query: 123 AA-----------------PSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPV------ 159
+ PS GAP A + P +E P V +
Sbjct: 840 SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 160 -CTIFSQRAPPASGDGFEPQMVKS-PSFGGA----SEASARTPPQVVQPSPSLSTFFGDT 213
T ++AP S P+ ++ P+ G S A TPP PSP G
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK-----GGP 954
Query: 214 AASHSLASDFFDSFTTSAFISVSNPGAGSPAP----ASPPPLAVPGTEGRPEPVAMRGPQ 269
A T S + + P A P+P A+P P P P GP
Sbjct: 955 A-------------TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 270 AAAPPASPEP 279
+P +P P
Sbjct: 1002 TPSPKGAPTP 1011
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 52.0 bits (123), Expect = 2e-06
Identities = 76/302 (25%), Positives = 89/302 (29%), Gaps = 70/302 (23%)
Query: 2 EDAGGGEETPAPEAPHPPQLAP-----PEEQGLLFQEETIDLGGDEFGSEENETASEGSS 56
E + GG P P P P+ P P QG F E G+S
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG--------------FQGPPGEPGEPGAS 214
Query: 57 -PLADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTP 108
P+ + P G GD G PG G PGP+ AG P
Sbjct: 215 GPMGPR------------GPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262
Query: 109 SPSGE--------ADGDCAP-----EDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAE 155
G A GD P E +P GAP Q R +PG E RP
Sbjct: 263 GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG-ERGRP------GA 315
Query: 156 PVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAA 215
P P + A A+G P F GA A PQ + S G+
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375
Query: 216 SHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPA 275
A NPGA P + PG G P RGP P
Sbjct: 376 PG----------PAGAAGPAGNPGADG-QPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424
Query: 276 SP 277
P
Sbjct: 425 GP 426
Score = 51.2 bits (121), Expect = 3e-06
Identities = 78/328 (23%), Positives = 94/328 (28%), Gaps = 42/328 (12%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGG--DEFGSEENETASEGSSPLADKLNE 64
G++ A + P + PP QG T L G G + A + P K
Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK--- 286
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGT------------PSPS 111
P S G+ G G++ PG G PG P PAG P P+
Sbjct: 287 ---------GEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT 337
Query: 112 GEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPAS 171
G A P P+ E P P P P + P A
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397
Query: 172 GDGFEPQMVKSPSFGGASEAS------ARTPPQVVQPSPSLSTFFGDTAASHSLASDFFD 225
G P + +P F GA S P+ P GDT A
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457
Query: 226 SFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQA 285
A G P P P PG G P G A P P A
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLP--GPPGERGGPGSRGFPGADGVAGPKGP-------A 508
Query: 286 VFAGSDDPFATALSMSEMDRRNDAWLPG 313
GS P S E R +A LPG
Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPG 536
Score = 50.4 bits (119), Expect = 6e-06
Identities = 69/249 (27%), Positives = 84/249 (33%), Gaps = 35/249 (14%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDA 135
P G AG+ G PG +G PGP AG P +G+ E P GAP
Sbjct: 622 PGPAGPAGERGEQGPAGSPGFQGLPGP--AGPPGEAGKPG-----EQGVPGDLGAPGPSG 674
Query: 136 AREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASART 195
AR G R Q PP A P +G +P GA +
Sbjct: 675 ARGERGFPGERGVQGPPGP------------AGPRGANG-------APGNDGAKGDAGAP 715
Query: 196 PPQVVQPSPSLSTFFGDTAASH--SLASDFFDSFTTSAFISVSNPGA-GSPAPASPP-PL 251
Q +P L G+ A+ D D+ A S G G P PP P
Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA 775
Query: 252 AVPGTEGRPEPVAMRGPQAA--APPASPEPFAHIQAVFA---GSDDPFATALSMSEMDRR 306
PG +G P GP A AP EP A FA G+D + +
Sbjct: 776 GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAK 835
Query: 307 NDAWLPGEA 315
DA PG A
Sbjct: 836 GDAGPPGPA 844
Score = 43.9 bits (102), Expect = 5e-04
Identities = 58/210 (27%), Positives = 65/210 (30%), Gaps = 47/210 (22%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDA-APSSGGAPRQDAAR 137
EG G G PG G PGP P P+GE A A AP + G R
Sbjct: 904 EGGKGPRGETGPAGRPGEVGPPGP-----PGPAGEKGSPGADGPAGAPGTPGPQGIAGQR 958
Query: 138 EVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPP 197
V G R E+ P P P Q ASG+ P + P G S R
Sbjct: 959 GVVGLPGQRGERGFP-GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017
Query: 198 QVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA----GSPAPASPPPLAV 253
+ SP +PGA G PA PP
Sbjct: 1018 PGAEGSPGRD----------------------------GSPGAKGDRGETGPAGPP--GA 1047
Query: 254 PGTEGRPEPVAM------RGPQAAAPPASP 277
PG G P PV RG A PA P
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/199 (27%), Positives = 67/199 (33%), Gaps = 47/199 (23%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQ 133
SP G G+ G + G G PGP+ G P P+G+ DG P P GA Q
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ-DGRPGP----PGPPGARGQ 576
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
PG + A E VP PP + P+ G EA A
Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVP--------GPPGA---------VGPA-GKDGEAGA 618
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLA- 252
+ PP P+ G+ S F G P PA PP A
Sbjct: 619 QGPPGPAGPA-------GERGEQGPAGSPGFQ---------------GLPGPAGPPGEAG 656
Query: 253 VPGTEGRPEPVAMRGPQAA 271
PG +G P + GP A
Sbjct: 657 KPGEQGVPGDLGAPGPSGA 675
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/143 (26%), Positives = 49/143 (34%), Gaps = 31/143 (21%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-------PEPAGTPSPSGEA--DGDCAPEDAAPS 126
P +GD GD G + PG +G G P PAG P GE+ G P A +
Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798
Query: 127 SG-----------------GAPRQDAAREVPGSEAARPEQEP-----PVAEPVPVCTIFS 164
G GA Q A+ PG A+ + P P P P+ + +
Sbjct: 799 PGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858
Query: 165 QRAPPASGDGFEPQMVKSPSFGG 187
A A G P P G
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAG 881
Score = 40.4 bits (93), Expect = 0.006
Identities = 56/215 (26%), Positives = 69/215 (32%), Gaps = 40/215 (18%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
+P G+ G G PG +G PG + G P +G A GD P A G P
Sbjct: 798 APGDRGEPGPPGPAGFAGPPGADGQPGAK--GEPGDAG-AKGDAGPPGPA-GPAGPPGPI 853
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPS--FGG----A 188
PG++ AR PP A P + PP P P+ GG
Sbjct: 854 GNVGAPGAKGARGSAGPPGATGFPGAA--GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRG 911
Query: 189 SEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP--APA 246
A P +V P P G S PGA P AP
Sbjct: 912 ETGPAGRPGEVGPPGPP-----GPAGEKGS-------------------PGADGPAGAPG 947
Query: 247 SPPPLAVPGTEGRPEPVAMRGPQA--AAPPASPEP 279
+P P + G G RG + P S EP
Sbjct: 948 TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982
Score = 37.0 bits (84), Expect = 0.066
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPA-GTPSPSGEADGDCAPEDAAPSSGGAPRQDAARE 138
G+ GD G G +G PGP + G PSG A G P P S GAP +D
Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSG-ASGPAGPR-GPPGSAGAPGKDGLNG 1157
Query: 139 VPG-----SEAARPEQEPPVAEPVP 158
+PG R PV P P
Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPGP 1182
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/232 (24%), Positives = 71/232 (30%), Gaps = 54/232 (23%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGP-EPAGTPSPSGEAD-----GDCAPEDA-APSS 127
SP ++GD G+ G PG G PGP PAG GE G P A P+
Sbjct: 1029 SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG 1088
Query: 128 GGAPRQDAA-------REVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMV 180
PR D R + G Q PP PP
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP--------------GPPG---------- 1124
Query: 181 KSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA 240
SP G S AS P+ G ++ + D +
Sbjct: 1125 -SPGEQGPSGASGPAGPR------------GPPGSAGAPGKDGLNGLPGPIGPPGPRGRT 1171
Query: 241 GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDD 292
G P PP PG G P P + G + P P+ AH + +DD
Sbjct: 1172 GDAGPVGPP--GPPGPPGPPGPPS-AGFDFSFLPQPPQEKAHDGGRYYRADD 1220
Score = 34.7 bits (78), Expect = 0.33
Identities = 57/223 (25%), Positives = 72/223 (32%), Gaps = 38/223 (17%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPE-----DAAPSSG----GA 130
G AG GR +PG G PG P G P P G G+ AP+ D + G G
Sbjct: 124 GPAGPPGRDGIPGQPGLPGPPG--PPGPPGPPG-LGGNFAPQLSYGYDEKSTGGISVPGP 180
Query: 131 PRQDAAREVPGSEAARPEQ--EPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGA 188
R +PG A Q + P EP P + P+ P
Sbjct: 181 MGPSGPRGLPGPPGAPGPQGFQGPPGEP----------GEPGASGPMGPRGPPGPPGKNG 230
Query: 189 SEASARTPPQVVQ---PSPSLSTFFGDTAASHSLAS----DFFDSFTTSAFISVSNPGAG 241
+ A P + + P P + TA + D A + G
Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290
Query: 242 SP----APASPPPLAVPGTEGR---PEPVAMRGPQAAAPPASP 277
SP AP P +PG GR P P RG A A P
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333
Score = 31.2 bits (69), Expect = 3.6
Identities = 55/214 (25%), Positives = 69/214 (32%), Gaps = 36/214 (16%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
+P + G G G E G G PGP+ G+ GD P+ A G+P +D
Sbjct: 714 APGAPGSQGAPGLQGMPGERGAAGLPGPK--------GDR-GDAGPKGA----DGSPGKD 760
Query: 135 AAREV-----PGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
R + P A P + P ++ AP GD EP F G
Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP---GDRGEPGPPGPAGFAG-- 815
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLA--SDFFDSFTTSAFISVSNPGA-GSPAPA 246
P P GD A + +V PGA G+ A
Sbjct: 816 -------PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 247 SPP-PLAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
PP PG GR P G A PP P P
Sbjct: 869 GPPGATGFPGAAGRVGPPGPSG--NAGPPGPPGP 900
Score = 31.2 bits (69), Expect = 3.6
Identities = 23/69 (33%), Positives = 25/69 (36%), Gaps = 14/69 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAG-----TPSPSGEADGDCAPEDAAPSSGGA 130
P G GD G V PG G PGP AG P P P++ A G
Sbjct: 1165 PGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP---------PQEKAHDGGRY 1215
Query: 131 PRQDAAREV 139
R D A V
Sbjct: 1216 YRADDANVV 1224
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/218 (30%), Positives = 81/218 (37%), Gaps = 25/218 (11%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P + G G GRV G G PGP P+G P G A GD P P G P
Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG-ARGDSGP----PGRAGEPGLQ 947
Query: 135 AAREVPGSEAARPEQEPPVAE-PVPVCTIFSQRA----PPASGD-GFE--PQMVKSPSFG 186
PG + + P AE P + QR P G+ GF P P
Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 1007
Query: 187 GASEASA-RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFI--------SVSN 237
GA AS R PP V P P L+ G+ S +D +A + +V
Sbjct: 1008 GAPGASGDRGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 1066
Query: 238 PGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPA 275
PGA P P SP P G +G +GP + PA
Sbjct: 1067 PGAPGP-PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/208 (29%), Positives = 71/208 (34%), Gaps = 34/208 (16%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAA--PSSGGAPR 132
P G G G D PG G+PG + PAG P GE GD P A P G
Sbjct: 920 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP-GDDGPSGAEGPPGPQGLAG 978
Query: 133 QDAAREVPGSEAAR--PEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASE 190
Q +PG R P P EP Q AP ASGD
Sbjct: 979 QRGIVGLPGQRGERGFPGLPGPSGEPG------KQGAPGASGD----------------- 1015
Query: 191 ASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP-APASPP 249
R PP V P P L+ G+ S +D +A + G+ AP +P
Sbjct: 1016 ---RGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071
Query: 250 PLAVPGTEGRPEPVAMRGPQAAAPPASP 277
P PG G RG A P P
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099
Score = 44.3 bits (103), Expect = 4e-04
Identities = 62/244 (25%), Positives = 76/244 (31%), Gaps = 50/244 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPA----GTPSPSG-----------EADGDC-A 119
P G GD G + G G PGP+ A GTP G A G+ A
Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304
Query: 120 P----EDAAPSSGGAPRQDAAREVPGSEA-----------ARPEQEPPVAEPVPVCTIFS 164
P E +P G+P R +PG Q P P PV
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV----- 359
Query: 165 QRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFF 224
PA G GF P + G + A Q + P G AS + +D
Sbjct: 360 ---GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI 415
Query: 225 DSFTTSAFISVSNPGAGSPAPASPP-------PLAVPGTEGRPEPVAMR---GPQAAAPP 274
SA G P P PP PL G G P + GP+ P
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475
Query: 275 ASPE 278
A P+
Sbjct: 476 AGPQ 479
Score = 43.1 bits (100), Expect = 0.001
Identities = 57/213 (26%), Positives = 69/213 (32%), Gaps = 21/213 (9%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
+P G+ G G PG +G PG + G +G+ AP PS GAP
Sbjct: 820 APGERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPS--GAPGPQ 875
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
V G + AR Q PP A P + PP S P PS G AR
Sbjct: 876 GPTGVTGPKGARGAQGPPGATGFPGAA--GRVGPPGSNGNPGPPGPPGPS-GKDGPKGAR 932
Query: 195 ----TPPQVVQPS-------PSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP 243
P + +P P GD S + I V PG
Sbjct: 933 GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI-VGLPGQRGE 991
Query: 244 A--PASPPPLAVPGTEGRPEPVAMRGPQAAAPP 274
P P P PG +G P RGP P
Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 1024
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/235 (24%), Positives = 72/235 (30%), Gaps = 32/235 (13%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-------------PAGTPSPSGEADGDCA 119
S SP G G +G PG G GP PAG P P G A G
Sbjct: 311 SGSPGENGSPGPMG---PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367
Query: 120 PEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTI---FSQRAPPASGDGFE 176
P AP + G AR G++ R E P P P + P A G
Sbjct: 368 P--GAPGAKGEAGPTGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDGIPGAKGSAGA 424
Query: 177 PQMVKSPSF------GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTS 230
P + +P F G A+ P+ P ++ F G+
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484
Query: 231 AFISVSNPGAGSP---APASPP-PLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
A G P P PP PG G P + GP+ A P A
Sbjct: 485 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 539
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/209 (27%), Positives = 71/209 (33%), Gaps = 21/209 (10%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGP--------EPA--GTPSPSGEADGDCAPEDAAPSSGG 129
GDAG G+V PG +G PGP +P G P P G A+G E G
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG-ANG----EPGKAGEKG 621
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
P R +PG + PP P Q AP SG P P GG
Sbjct: 622 LPGAPGLRGLPGKDGETGAAGPP-GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG-K 679
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP 249
P + +P L G+ S + PG P AS
Sbjct: 680 PGDQGVPGEA--GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP-GTPGTDGPKGAS-G 735
Query: 250 PLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P PG +G P M G + AA A P+
Sbjct: 736 PAGPPGAQGPPGLQGMPGERGAAGIAGPK 764
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/208 (25%), Positives = 68/208 (32%), Gaps = 50/208 (24%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAA--PSSGGAP 131
+P G+ G G + PG G PG + AG P +GE G P+ A P + G P
Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER-GPPGPQGARGFPGTPGLP 284
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEA 191
R PG + A+ E AP G+ P SP
Sbjct: 285 GVKGHRGYPGLDGAKGE----------------AGAPGVKGESGSPGENGSPG------- 321
Query: 192 SARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG-AGSPAPASPPP 250
P + P G A+ + +D PG AG P P P
Sbjct: 322 -----PMGPRGLPGERGRTGPAGAAGARGND-------------GQPGPAGPPGPVGPAG 363
Query: 251 ----LAVPGTEGRPEPVAMRGPQAAAPP 274
PG +G P RGP+ A P
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGP 391
Score = 40.0 bits (92), Expect = 0.008
Identities = 54/202 (26%), Positives = 69/202 (34%), Gaps = 36/202 (17%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAP 131
S P +G G+ G ++D P +G PGP+ PAG P G+ GD E AP G
Sbjct: 97 SGQPGPKGQKGEPGDIKDIVGP--KGPPGPQGPAGEQGPRGDR-GD-KGEKGAPGPRG-- 150
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEA 191
+D PG+ PP PP G F QM GG E
Sbjct: 151 -RDGEPGTPGNPGPPGPPGPP--------------GPPGLGGNFAAQMA-----GGFDEK 190
Query: 192 SARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP-APASPP- 249
+ V+Q G + + F PG P P PP
Sbjct: 191 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP----GEPGVSGPMGPRGPPG 246
Query: 250 PLAVPGTE---GRPEPVAMRGP 268
P PG + G+P RGP
Sbjct: 247 PPGKPGDDGEAGKPGKAGERGP 268
Score = 38.1 bits (87), Expect = 0.029
Identities = 58/209 (27%), Positives = 74/209 (35%), Gaps = 36/209 (17%)
Query: 79 EGDAGDLGRVRDEAEPG---GEGDPGPEPAGTPSPSGE--ADGDCAPEDAAPSSGGAPRQ 133
+GD GD+G E PG G G G P G P P+G G+ P A S+G
Sbjct: 764 KGDRGDVGEKGPEGAPGKDGGRGLTG--PIGPPGPAGANGEKGEVGPPGPAGSAG----- 816
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
AR PG R E PP + A P DG +P G +
Sbjct: 817 --ARGAPGE---RGETGPPGP---------AGFAGPPGADG-QPGAKGEQGEAGQKGDAG 861
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFT--TSAFISVSNPGA-GSPAPASPPP 250
PQ +P G T + + T A V PG+ G+P P P
Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-- 919
Query: 251 LAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
PG G+ P RG + P + EP
Sbjct: 920 ---PGPSGKDGPKGARG-DSGPPGRAGEP 944
Score = 35.4 bits (80), Expect = 0.19
Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 17/202 (8%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP-EDAAPSSGGAPRQDAARE 138
G AG+ G+ EPGG G P G P G P +D GAP +
Sbjct: 483 GPAGEEGKRGARGEPGGVG-----PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537
Query: 139 VPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTP-P 197
+ G + A + P +P + R A PQ PS + P P
Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG-----PQGKVGPSGAPGEDGRPGPPGP 592
Query: 198 QVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVP--- 254
Q + P + F G A+ + + G A PP A P
Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 652
Query: 255 -GTEGRPEPVAMRG-PQAAAPP 274
G +G P P +G P PP
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPP 674
Score = 32.7 bits (73), Expect = 1.2
Identities = 50/198 (25%), Positives = 64/198 (32%), Gaps = 32/198 (16%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQ 133
+P G +G G +PG G+PG P G GD P+ S GAP +
Sbjct: 529 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG----RPGDAGPQGKVGPS-GAPGE 583
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGA----S 189
D PG + AR Q + P P + A G E + +P G
Sbjct: 584 DGRPGPPGPQGAR-GQPGVMGFPGP------KGANGEPGKAGEKGLPGAPGLRGLPGKDG 636
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP 249
E A PP P+ G+ A S F + P P
Sbjct: 637 ETGAAGPPGPAGPAGER----GEQGAP-----------GPSGFQGLPGPPGPPGEGGKPG 681
Query: 250 PLAVPGTEGRPEPVAMRG 267
VPG G P V RG
Sbjct: 682 DQGVPGEAGAPGLVGPRG 699
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/218 (30%), Positives = 81/218 (37%), Gaps = 25/218 (11%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P + G G GRV G G PGP P+G P G A GD P P G P
Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG-ARGDSGP----PGRAGEPGLQ 878
Query: 135 AAREVPGSEAARPEQEPPVAE-PVPVCTIFSQRA----PPASGD-GFE--PQMVKSPSFG 186
PG + + P AE P + QR P G+ GF P P
Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 938
Query: 187 GASEASA-RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFI--------SVSN 237
GA AS R PP V P P L+ G+ S +D +A + +V
Sbjct: 939 GAPGASGDRGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 997
Query: 238 PGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPA 275
PGA P P SP P G +G +GP + PA
Sbjct: 998 PGAPGP-PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/208 (29%), Positives = 71/208 (34%), Gaps = 34/208 (16%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAA--PSSGGAPR 132
P G G G D PG G+PG + PAG P GE GD P A P G
Sbjct: 851 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP-GDDGPSGAEGPPGPQGLAG 909
Query: 133 QDAAREVPGSEAAR--PEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASE 190
Q +PG R P P EP Q AP ASGD
Sbjct: 910 QRGIVGLPGQRGERGFPGLPGPSGEPG------KQGAPGASGD----------------- 946
Query: 191 ASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP-APASPP 249
R PP V P P L+ G+ S +D +A + G+ AP +P
Sbjct: 947 ---RGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1002
Query: 250 PLAVPGTEGRPEPVAMRGPQAAAPPASP 277
P PG G RG A P P
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030
Score = 44.3 bits (103), Expect = 4e-04
Identities = 62/244 (25%), Positives = 76/244 (31%), Gaps = 50/244 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPA----GTPSPSG-----------EADGDC-A 119
P G GD G + G G PGP+ A GTP G A G+ A
Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235
Query: 120 P----EDAAPSSGGAPRQDAAREVPGSEA-----------ARPEQEPPVAEPVPVCTIFS 164
P E +P G+P R +PG Q P P PV
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV----- 290
Query: 165 QRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFF 224
PA G GF P + G + A Q + P G AS + +D
Sbjct: 291 ---GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI 346
Query: 225 DSFTTSAFISVSNPGAGSPAPASPP-------PLAVPGTEGRPEPVAMR---GPQAAAPP 274
SA G P P PP PL G G P + GP+ P
Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 406
Query: 275 ASPE 278
A P+
Sbjct: 407 AGPQ 410
Score = 43.1 bits (100), Expect = 0.001
Identities = 57/213 (26%), Positives = 69/213 (32%), Gaps = 21/213 (9%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
+P G+ G G PG +G PG + G +G+ AP PS GAP
Sbjct: 751 APGERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPS--GAPGPQ 806
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
V G + AR Q PP A P + PP S P PS G AR
Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAA--GRVGPPGSNGNPGPPGPPGPS-GKDGPKGAR 863
Query: 195 ----TPPQVVQPS-------PSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP 243
P + +P P GD S + I V PG
Sbjct: 864 GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI-VGLPGQRGE 922
Query: 244 A--PASPPPLAVPGTEGRPEPVAMRGPQAAAPP 274
P P P PG +G P RGP P
Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 955
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/235 (24%), Positives = 72/235 (30%), Gaps = 32/235 (13%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-------------PAGTPSPSGEADGDCA 119
S SP G G +G PG G GP PAG P P G A G
Sbjct: 242 SGSPGENGSPGPMG---PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298
Query: 120 PEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTI---FSQRAPPASGDGFE 176
P AP + G AR G++ R E P P P + P A G
Sbjct: 299 P--GAPGAKGEAGPTGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDGIPGAKGSAGA 355
Query: 177 PQMVKSPSF------GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTS 230
P + +P F G A+ P+ P ++ F G+
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415
Query: 231 AFISVSNPGAGSP---APASPP-PLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
A G P P PP PG G P + GP+ A P A
Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/209 (27%), Positives = 71/209 (33%), Gaps = 21/209 (10%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGP--------EPA--GTPSPSGEADGDCAPEDAAPSSGG 129
GDAG G+V PG +G PGP +P G P P G A+G E G
Sbjct: 498 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG-ANG----EPGKAGEKG 552
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
P R +PG + PP P Q AP SG P P GG
Sbjct: 553 LPGAPGLRGLPGKDGETGAAGPP-GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG-K 610
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP 249
P + +P L G+ S + PG P AS
Sbjct: 611 PGDQGVPGEA--GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP-GTPGTDGPKGAS-G 666
Query: 250 PLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P PG +G P M G + AA A P+
Sbjct: 667 PAGPPGAQGPPGLQGMPGERGAAGIAGPK 695
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/208 (25%), Positives = 68/208 (32%), Gaps = 50/208 (24%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAA--PSSGGAP 131
+P G+ G G + PG G PG + AG P +GE G P+ A P + G P
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER-GPPGPQGARGFPGTPGLP 215
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEA 191
R PG + A+ E AP G+ P SP
Sbjct: 216 GVKGHRGYPGLDGAKGE----------------AGAPGVKGESGSPGENGSPG------- 252
Query: 192 SARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG-AGSPAPASPPP 250
P + P G A+ + +D PG AG P P P
Sbjct: 253 -----PMGPRGLPGERGRTGPAGAAGARGND-------------GQPGPAGPPGPVGPAG 294
Query: 251 ----LAVPGTEGRPEPVAMRGPQAAAPP 274
PG +G P RGP+ A P
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGP 322
Score = 38.1 bits (87), Expect = 0.029
Identities = 58/209 (27%), Positives = 74/209 (35%), Gaps = 36/209 (17%)
Query: 79 EGDAGDLGRVRDEAEPG---GEGDPGPEPAGTPSPSGE--ADGDCAPEDAAPSSGGAPRQ 133
+GD GD+G E PG G G G P G P P+G G+ P A S+G
Sbjct: 695 KGDRGDVGEKGPEGAPGKDGGRGLTG--PIGPPGPAGANGEKGEVGPPGPAGSAG----- 747
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
AR PG R E PP + A P DG +P G +
Sbjct: 748 --ARGAPGE---RGETGPPGP---------AGFAGPPGADG-QPGAKGEQGEAGQKGDAG 792
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFT--TSAFISVSNPGA-GSPAPASPPP 250
PQ +P G T + + T A V PG+ G+P P P
Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-- 850
Query: 251 LAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
PG G+ P RG + P + EP
Sbjct: 851 ---PGPSGKDGPKGARG-DSGPPGRAGEP 875
Score = 35.4 bits (80), Expect = 0.19
Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 17/202 (8%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP-EDAAPSSGGAPRQDAARE 138
G AG+ G+ EPGG G P G P G P +D GAP +
Sbjct: 414 GPAGEEGKRGARGEPGGVG-----PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468
Query: 139 VPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTP-P 197
+ G + A + P +P + R A PQ PS + P P
Sbjct: 469 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG-----PQGKVGPSGAPGEDGRPGPPGP 523
Query: 198 QVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVP--- 254
Q + P + F G A+ + + G A PP A P
Sbjct: 524 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 583
Query: 255 -GTEGRPEPVAMRG-PQAAAPP 274
G +G P P +G P PP
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPP 605
Score = 32.7 bits (73), Expect = 1.2
Identities = 50/198 (25%), Positives = 64/198 (32%), Gaps = 32/198 (16%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQ 133
+P G +G G +PG G+PG P G GD P+ S GAP +
Sbjct: 460 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG----RPGDAGPQGKVGPS-GAPGE 514
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGA----S 189
D PG + AR Q + P P + A G E + +P G
Sbjct: 515 DGRPGPPGPQGAR-GQPGVMGFPGP------KGANGEPGKAGEKGLPGAPGLRGLPGKDG 567
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP 249
E A PP P+ G+ A S F + P P
Sbjct: 568 ETGAAGPPGPAGPAGER----GEQGAP-----------GPSGFQGLPGPPGPPGEGGKPG 612
Query: 250 PLAVPGTEGRPEPVAMRG 267
VPG G P V RG
Sbjct: 613 DQGVPGEAGAPGLVGPRG 630
Score = 30.8 bits (68), Expect = 4.7
Identities = 62/264 (23%), Positives = 77/264 (29%), Gaps = 84/264 (31%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-------------PAGTPSPSGE--ADGDCAP 120
P +G AG+ G D + G +G PGP P G P P G G+ A
Sbjct: 53 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 112
Query: 121 EDAA--------------------------PSSGGAPRQDAAREVPGSEAARPEQEPPVA 154
+ A P GAP + PG EP V+
Sbjct: 113 QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG-----EPGVS 167
Query: 155 EPVPVCTIFSQRAPPA----SGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFF 210
P+ R PP GD E G +A R P P P + F
Sbjct: 168 GPM------GPRGPPGPPGKPGDDGEA--------GKPGKAGERGP-----PGPQGARGF 208
Query: 211 GDTAASHSLASDFFDSFTTSAFISVSNPG----AGSP----APASPPPLAVPGTEGRPEP 262
T + A PG +GSP +P P +PG GR P
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268
Query: 263 VAMRG-------PQAAAPPASPEP 279
G P A PP P
Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGP 292
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/218 (30%), Positives = 80/218 (36%), Gaps = 25/218 (11%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDA----APSSGGA 130
SP G AG G PG G+PGP P PSG D P A AP S G
Sbjct: 865 SPGGPGAAGFPGARGLPGPPGSNGNPGP-----PGPSGSPGKDGPPGPAGNTGAPGSPGV 919
Query: 131 --PRQDAAREVPGSEAARPEQEPPVAE-PVPVCTIFSQRA------PPASGDGFEPQMVK 181
P+ DA + PG + + Q PP A P+ + I R P PQ VK
Sbjct: 920 SGPKGDAGQ--PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977
Query: 182 SPSFG-GASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA 240
S GA+ S P Q P L+ G+ + SD S
Sbjct: 978 GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037
Query: 241 GSP-APASPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
GSP AP +P PG G P G + + PA P
Sbjct: 1038 GSPGAPGAP---GHPGPPGPVGPAGKSGDRGESGPAGP 1072
Score = 48.5 bits (114), Expect = 2e-05
Identities = 54/200 (27%), Positives = 68/200 (34%), Gaps = 22/200 (11%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
SP +G G+ G+ G G PGP+ G P +G A D P S G P +D
Sbjct: 970 SPGPQGVKGESGKPGANGLSGERGPPGPQ--GLPGLAGTAGEP--GRDGNPGSDGLPGRD 1025
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
+ PG + R E P A P PA G + + G A +R
Sbjct: 1026 GS---PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 195 TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVP 254
P P G+T + F NPGA P SP P
Sbjct: 1083 GAPGPQGPRGDK----GETGERGAAGIKGHRGFP-------GNPGA----PGSPGPAGQQ 1127
Query: 255 GTEGRPEPVAMRGPQAAAPP 274
G G P P RGP + P
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGP 1147
Score = 48.1 bits (113), Expect = 3e-05
Identities = 63/234 (26%), Positives = 78/234 (33%), Gaps = 52/234 (22%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQ 133
SP +GD G+ G + PG +G GP P G P P+G+ GD GGAP
Sbjct: 736 SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ-PGD-------KGEGGAPGL 787
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCT--------IFSQRAPPASGDGFEPQMVKSPSF 185
GS R E PP P + AP G+G P + P
Sbjct: 788 PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP-- 845
Query: 186 GGASEASARTPPQV-----VQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG- 239
GG+ A P V P + F G S+ NPG
Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN-------------GNPGP 892
Query: 240 ---AGSPAPASPP-PLAVPGTEGRP----------EPVAMRGPQAAAPPASPEP 279
+GSP PP P G G P +P P A PP +P P
Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP 946
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/210 (25%), Positives = 65/210 (30%), Gaps = 26/210 (12%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTPSPSGEADGDCAPEDAAPSSG 128
P +G+ G G+ + PGG G GP P G P P+G GD
Sbjct: 581 PGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG-GD-------KGDT 632
Query: 129 GAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGA 188
G P + +PG+ E P EP P + AP GD P P GA
Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKP-GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691
Query: 189 SEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAP-AS 247
P P P G A+ + G GSP P
Sbjct: 692 PGLRGGAGP----PGPE-----GGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742
Query: 248 PPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
PG +G P RGP P P
Sbjct: 743 KGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/220 (25%), Positives = 73/220 (33%), Gaps = 19/220 (8%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTP-SPSGEADGDCAPEDAAPSSGGAPRQ 133
P +G G G E G G+PGP+ AG P +P G+ D E P GAP
Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694
Query: 134 DAAREVPGSE----AARPEQEPPVAEPVPVCTIFSQR----APPASGDGFEPQMVKSPSF 185
PG E AA P P A + + +R +P GD EP +
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754
Query: 186 GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG-AGSPA 244
G T P + P P+ + L + PG AG P
Sbjct: 755 PGKDGPRGPTGP-IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG 813
Query: 245 -------PASPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
P PG +G P + GP + PA P
Sbjct: 814 APGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853
Score = 41.2 bits (95), Expect = 0.003
Identities = 59/222 (26%), Positives = 72/222 (32%), Gaps = 40/222 (18%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTP----SPSGEADGDCAPEDA 123
SP ++G+ G G PG G+PGP+ P G P SP G+ + A
Sbjct: 346 SPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPG 405
Query: 124 APSSGGA---PRQDAAREVPG--SEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQ 178
AP GA P A PG A P + EP P P G E
Sbjct: 406 APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG 465
Query: 179 MVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNP 238
SP GA+ AA A F + P
Sbjct: 466 KDGSPGEPGANGLPG--------------------AAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 239 GA--GSPAPASPPPLA-VPGTEGRPEPVAMRG-PQAAAPPAS 276
G+P PA P A PG +G P MRG P + P S
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/273 (23%), Positives = 88/273 (32%), Gaps = 30/273 (10%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEP-AGTPSPSGEADGDCAPEDAAPSSGGAPRQ 133
+P G AG+ G+ + EPG G+ G G P GE D +P + P + G P
Sbjct: 424 APGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE--PGANGLPGA 481
Query: 134 DAAREVPGSEAAR-----PEQEPPVAE---PVPVCTIFSQRAPPASGDGFEPQMVKSPSF 185
R PG P ++ P E P P + P G P M P
Sbjct: 482 AGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541
Query: 186 GGASEASARTPPQVVQ--------PSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSN 237
G + + P Q P PS G + + +
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPGPPGPS-----GPRGQPGVMGFPGPKGNDGAPGKNGER 596
Query: 238 PGAGSPAPASPP-PLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFAT 296
G G P P PP G +G P P G + P P+ + G+ P
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL----PGTGGPPGE 652
Query: 297 ALSMSEMDRRNDAWLPGEATRGVLRAVATQQRG 329
E + DA PG A G A A +RG
Sbjct: 653 NGKPGEPGPKGDAGAPG-APGGKGDAGAPGERG 684
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 5/89 (5%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSG--EADGDCAPEDAAPSSG--G 129
+P + G GD G + PG G PG AG P P G A G P AA + G G
Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVP 158
P + PG + + E P A+ VP
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVP 755
Score = 35.8 bits (81), Expect = 0.15
Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 6/78 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P G AG G G G PGP AG P G A G+ P +P S GAP Q
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG-AKGEVGPA-GSPGSNGAPGQ- 367
Query: 135 AAREVPGSEAARPEQEPP 152
R PG + Q PP
Sbjct: 368 --RGEPGPQGHAGAQGPP 383
Score = 35.8 bits (81), Expect = 0.15
Identities = 56/239 (23%), Positives = 70/239 (29%), Gaps = 56/239 (23%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAA----PSSGGA 130
+P G AG G ++ G G PGP AG +GE D P P S G
Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGP--AGPRGAAGEPGRDGVPGGPGMRGMPGSPGG 544
Query: 131 PRQDAAREVPGSEAARPEQEPP-----------VAEPVPVCTIFSQ-------------- 165
P D PGS+ PP + P P +
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604
Query: 166 RAPPASGDGFEPQMVKSPSFGGASEASARTP-PQVVQPSPSLSTFFGDTAASHSLASDFF 224
+ PP PQ P+ G + P PQ +Q P G+
Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP-------- 656
Query: 225 DSFTTSAFISVSNPG----AGSP-APASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
PG AG+P AP PG G P G + A P PE
Sbjct: 657 -----------GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704
Score = 33.5 bits (75), Expect = 0.73
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 224 FDSFTTSAFISVSNPGAGSPAPASPP-PLAVPGTEGRPEPVAMRGPQAAAPPASP 277
+DS+ + ++V AG P PA PP P PGT G P G Q PP P
Sbjct: 155 YDSYDVKSGVAVGGL-AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQ--GPPGEP 206
Score = 33.5 bits (75), Expect = 0.73
Identities = 35/126 (27%), Positives = 41/126 (32%), Gaps = 13/126 (10%)
Query: 74 DSPNSE-GDAGDLGRVRDEAEPGGEGDPGP-EPAGTPSPSGEADGDCAPEDAAPSSGGAP 131
D N E G+ G G + PG G PGP P G P G P + GA
Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG--------RPGLPGAAGAR 320
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEA 191
D AR GS+ PP P PA G + G A
Sbjct: 321 GNDGAR---GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377
Query: 192 SARTPP 197
A+ PP
Sbjct: 378 GAQGPP 383
Score = 32.7 bits (73), Expect = 1.2
Identities = 56/215 (26%), Positives = 68/215 (31%), Gaps = 20/215 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGEADGDCAPEDAAPSSG--GAPR 132
P G G G PG +G PG P AG P G G P A G G P
Sbjct: 179 PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG-PPGAIGPSGPAGKDGESGRPG 237
Query: 133 QDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQR--------APPASGDGFEPQMVKSPS 184
+ R +PG + P + F R AP G+ P +P
Sbjct: 238 RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPG 297
Query: 185 FGGASEASARTPPQVVQPS-PSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP 243
G A P + +P P + G+ A S +A S G
Sbjct: 298 PMGPRGA----PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353
Query: 244 APA-SPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
PA SP PG G P P G Q PP P
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQ--GPPGPP 386
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/133 (25%), Positives = 45/133 (33%), Gaps = 12/133 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADG-DCAPEDAAPSSGGA 130
PN +G G G PG GDPG P G+P P G + P++ +P
Sbjct: 99 PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSY 158
Query: 131 PRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASE 190
+ G A P P P P T +P + G P G A
Sbjct: 159 DVKSGV--AVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP-----GEPGQAGP 211
Query: 191 ASARTPPQVVQPS 203
+ PP + PS
Sbjct: 212 SGPPGPPGAIGPS 224
Score = 30.4 bits (67), Expect = 6.1
Identities = 23/86 (26%), Positives = 28/86 (32%), Gaps = 5/86 (5%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
+P S G AG G + PG G G P G P G+ P P R +
Sbjct: 1117 APGSPGPAGQQGAI---GSPGPAGPRG--PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE 1171
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVC 160
E +P P P P C
Sbjct: 1172 RGSEGSPGHPGQPGPPGPPGAPGPCC 1197
>gi|71043876 undifferentiated embryonic cell transcription factor 1
[Homo sapiens]
Length = 341
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/87 (37%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 81 DAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSG-GAPRQDAAREV 139
DA +R P D P P P+P+ A C PED AP G G+P ARE
Sbjct: 195 DADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPARED 254
Query: 140 PGSEAARPEQ-EPPVAEPVPVCTIFSQ 165
P S RPE PP A P + T Q
Sbjct: 255 PDSPPGRPEDCAPPPAAPPSLNTALLQ 281
Score = 37.0 bits (84), Expect = 0.066
Identities = 50/162 (30%), Positives = 63/162 (38%), Gaps = 38/162 (23%)
Query: 115 DGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDG 174
+G P +P SG R A R VP + A P + P A P+P T + A P
Sbjct: 150 NGRKRPRRRSPGSGRPQR--ARRPVPNAHAPAPSE--PDATPLP--TARDRDADPTWTLR 203
Query: 175 FEPQMVKSPSFGGASEASARTPPQVVQPSPS-LSTFFGDTAASHSLASDFFDSFTTSAFI 233
F P KS AS A P P+P+ L+T + A
Sbjct: 204 FSPSPPKSAD---ASPAPGSPPA----PAPTALATCIPEDRAP----------------- 239
Query: 234 SVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPA 275
V PG+ P PA P + P GRPE A P AAPP+
Sbjct: 240 -VRGPGSPPPPPAREDPDSPP---GRPEDCA---PPPAAPPS 274
Score = 33.9 bits (76), Expect = 0.56
Identities = 31/112 (27%), Positives = 35/112 (31%), Gaps = 23/112 (20%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPG--------------PEPAGTPSPSGEADGDCAPEDAAP 125
G GD GR R G G P EP TP P+ D D P
Sbjct: 145 GLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTAR-DRDADPTWTLR 203
Query: 126 SSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEP 177
S P+ A PGS PP P + T + P G G P
Sbjct: 204 FSPSPPKSADASPAPGS--------PPAPAPTALATCIPEDRAPVRGPGSPP 247
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 51.2 bits (121), Expect = 3e-06
Identities = 58/205 (28%), Positives = 72/205 (35%), Gaps = 43/205 (20%)
Query: 75 SPNSEGDAGDLGRVRDEAEPGGEGDPGPEPA-GTPSPSGE--ADGDCAPEDAA--PSSGG 129
+P G G G V ++ E G GDPGP A G P P G+ GD P AA P G
Sbjct: 1188 TPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKG 1247
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
P +D A+ G + PP V + G+ +P V P GAS
Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGV-------SGIDGSPGEKGDPGDVGGPGPPGAS 1300
Query: 190 -EASARTPPQVVQPSPSLST--FFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPA 246
E A PP PS + G+ A G P P
Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAK------------------------GEPGPD 1336
Query: 247 SPP----PLAVPGTEGRPEPVAMRG 267
PP P+ G GR P +RG
Sbjct: 1337 GPPGRTGPMGARGPPGRVGPEGLRG 1361
Score = 40.8 bits (94), Expect = 0.005
Identities = 51/207 (24%), Positives = 65/207 (31%), Gaps = 57/207 (27%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSG--GAPRQ 133
P +G GD G V PG +G+ G E G P P+G+A G+ P G G +
Sbjct: 559 PGEKGQRGDFGHVGQPGPPGEDGERGAE--GPPGPTGQA-GEPGPRGLLGPRGSPGPTGR 615
Query: 134 DAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
+ G+ A+ PP EP PP Q + P G
Sbjct: 616 PGVTGIDGAPGAKGNVGPP-GEP----------GPPGQQGNHGSQGLPGPQ-GLIGTPGE 663
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAV 253
+ PP NPG P S PL
Sbjct: 664 KGPP--------------------------------------GNPGIPG-LPGSDGPLGH 684
Query: 254 PGTEGRPEPVAMRGPQ-AAAPPASPEP 279
PG EG +GP +A PP P P
Sbjct: 685 PGHEGPTGEKGAQGPPGSAGPPGYPGP 711
Score = 39.3 bits (90), Expect = 0.013
Identities = 51/205 (24%), Positives = 68/205 (33%), Gaps = 26/205 (12%)
Query: 72 ISDSPNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGEADGDCAPEDAAPSSGGA 130
I SP +GD GD+G PG G+PG P P G PSG + G
Sbjct: 1278 IDGSPGEKGDPGDVG---GPGPPGASGEPGAPGPPGKRGPSGHMGRE-----------GR 1323
Query: 131 PRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASE 190
+ A+ PG + P + P+ P + + G EP ++ +P G
Sbjct: 1324 EGEKGAKGEPGPDGP-PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMG--- 1379
Query: 191 ASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP- 249
PP + PS L GDT + G P PP
Sbjct: 1380 -----PPGPLGPS-GLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPG 1433
Query: 250 PLAVPGTEGRPEPVAMRGPQAAAPP 274
P PG G + GP A P
Sbjct: 1434 PKGDPGPPGPIGSLGHPGPPGVAGP 1458
Score = 37.0 bits (84), Expect = 0.066
Identities = 53/211 (25%), Positives = 64/211 (30%), Gaps = 28/211 (13%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP----EDAAPSSGGAP 131
P EG+ G G + +PG G PGP+ G+ D AP E P G P
Sbjct: 826 PGLEGERGPPGSRGERGQPGATGQPGPK--------GDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 132 RQDAAREVPGSEA--ARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
+ PG + RP E Q PP PQ K+ G
Sbjct: 878 GFPGPKGPPGHQGKDGRPGHPGQRGE----LGFQGQTGPPGPAGVLGPQ-GKTGEVGPLG 932
Query: 190 EASARTP--PQVVQPSPSLSTFFGDTAASHSLASDF-FDSFTTSAFISVSNPGAGSPAPA 246
E P P Q P L G A L + P G P
Sbjct: 933 ERGPPGPPGPPGEQGLPGLE---GREGAKGELGPPGPLGKEGPAGLRGFPGPKGG---PG 986
Query: 247 SPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
P P + G +G P PV G P P
Sbjct: 987 DPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017
Score = 36.2 bits (82), Expect = 0.11
Identities = 73/295 (24%), Positives = 89/295 (30%), Gaps = 63/295 (21%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
GE P E P PP EQGL G E E A P
Sbjct: 926 GEVGPLGERGPPGPPGPPGEQGLP-------------GLEGREGAKGELGP--------- 963
Query: 67 MESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADGDCAPED 122
P G G G GG GDPGP G P P G
Sbjct: 964 ---------PGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014
Query: 123 AAPSSG-GAPRQDAAREVP----GSEAARPEQEPPVAE-----PVPVCTIFSQRAPPASG 172
P+ G G P Q + E P G + +R E+ PP P P+ + A SG
Sbjct: 1015 LGPAGGIGLPGQSGS-EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073
Query: 173 DGFEPQMVKSP----SFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFF---D 225
+ + V +P S G +A P + P+ D A F
Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133
Query: 226 SFTTSAFISVSNPGA--GSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
F+ V P G P P PG +G V GP A P P+
Sbjct: 1134 DDGVRGFVGVIGPPGLQGLPGP--------PGEKGEVGDVGSMGPHGAPGPRGPQ 1180
Score = 35.4 bits (80), Expect = 0.19
Identities = 51/215 (23%), Positives = 69/215 (32%), Gaps = 38/215 (17%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREV 139
G GD+G D+ +PG G G + G P G+A A E+ P S G + +
Sbjct: 737 GFKGDVGLKGDQGKPGAPGPRGED--GPEGPKGQAGQ--AGEEGPPGSAGEKGKLGVPGL 792
Query: 140 PGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGD-GFEPQMVKSPSFGGASEASARTPPQ 198
PG RP + + P P+ I + +G G E + S G + P
Sbjct: 793 PG-YPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQ-----PGA 846
Query: 199 VVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP--------- 249
QP P GD + D + G P P PP
Sbjct: 847 TGQPGPK-----GD------VGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895
Query: 250 -------PLAVPGTEGRPEPVAMRGPQAAAPPASP 277
L G G P P + GPQ P
Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGP 930
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 13/125 (10%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGE--ADGDCAPEDAAPSSG-----GAP 131
+G G++G + + PG G PG + G P G A G+ P G G P
Sbjct: 922 QGKTGEVGPLGERGPPGPPGPPGEQ--GLPGLEGREGAKGELGPPGPLGKEGPAGLRGFP 979
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAP--PASGDGFEPQMVKSPSFGGAS 189
PG + ++ PP PV +R P PA G G Q G A
Sbjct: 980 GPKGGPGDPGPTGLKGDKGPP--GPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAG 1037
Query: 190 EASAR 194
+ +R
Sbjct: 1038 KKGSR 1042
Score = 30.8 bits (68), Expect = 4.7
Identities = 39/138 (28%), Positives = 44/138 (31%), Gaps = 35/138 (25%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P + G G +G PG GDPGP PAG P G P D
Sbjct: 394 PGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLP--------------------GIPGID 433
Query: 135 AAREVPGSEAARPEQ-------EPPV------AEPVPVCTIFSQRAPPAS-GDGFEPQMV 180
R PG+ P Q PPV A+ V T S + PP G P V
Sbjct: 434 GIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPV 493
Query: 181 KSPSFGGASEASARTPPQ 198
P G PQ
Sbjct: 494 GLPGHPGLKGEEGAEGPQ 511
Score = 30.0 bits (66), Expect = 8.0
Identities = 24/87 (27%), Positives = 30/87 (34%), Gaps = 11/87 (12%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSG----------EADGDCAPEDAA 124
P S+G G G E G +G PG P G P P G + + ED
Sbjct: 676 PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGF 735
Query: 125 PSSGGAPRQDAAREVPGSEAARPEQEP 151
P G + PG+ R E P
Sbjct: 736 PGFKGDVGLKGDQGKPGAPGPRGEDGP 762
Score = 30.0 bits (66), Expect = 8.0
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 1/38 (2%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSG 112
P G AG LG+ + PG G G PAG P P G
Sbjct: 1450 PGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487
>gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]
Length = 1024
Score = 50.4 bits (119), Expect = 6e-06
Identities = 76/320 (23%), Positives = 108/320 (33%), Gaps = 54/320 (16%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
G P PP+ APP G+ ++ + G G + ++ + E
Sbjct: 245 GSLDPPSSGAKPPEQAPPSPPGVGSRQGS----GVAVGRAAKYSETDLDTVPLRCYRETD 300
Query: 67 MESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPS 126
++ VL + E D+ + E PG P P P P P ED +
Sbjct: 301 IDEVL---AEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEA 357
Query: 127 SGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASG-DGFE---PQMVKS 182
G D E SE ARP P+ PVP +P A G D F +++S
Sbjct: 358 GGEEDVDDEVFEA--SEGARPGSRMPLKSPVP---FLPGTSPSADGPDSFSCVFEAILES 412
Query: 183 PSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGS 242
G S S + + P P+ S FF F P A
Sbjct: 413 HRAKGTSYTSLASLEALASPGPTQSPFF--------------------TFELPPQPPAPR 452
Query: 243 PAPASPPPLAV----PGTEGRPE-PVAMRGPQAAA----------PPASP---EPFAHIQ 284
P P +P PLA GT + P RG + A P SP E +
Sbjct: 453 PDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLG 512
Query: 285 AVFAGSDDPFATALSMSEMD 304
A GS+ P + +S S+ +
Sbjct: 513 AAPLGSEPPLSQLVSDSDSE 532
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 50.1 bits (118), Expect = 7e-06
Identities = 72/294 (24%), Positives = 100/294 (34%), Gaps = 38/294 (12%)
Query: 5 GGGEETPAPEAPHPPQLAPPEEQ-GLLFQEETIDLGGDEFGSEENETASEGSSPLADKLN 63
GG P P P PP +A PE G + T G +++
Sbjct: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
Query: 64 EHMMESVL---------ISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEA 114
+ M+ VL + P G GG GD P P P P G A
Sbjct: 69 QKQMQCVLQPHHLPPPPLPPPPVMPG--------------GGYGDWQPPPPPMPPPPGPA 114
Query: 115 DGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDG 174
+ R VP E P + PPV + S PP
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGPPGLVP-MELESPPESPPVPPGSYMPPSQSYMPPPQPPPS 173
Query: 175 FEPQMVKSPSFGGASEASARTPP--QVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF 232
+ P P A + +++PP + P+PS S+ +++S S S S+ S+
Sbjct: 174 YYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSS---SSSSSQSYLS-HSQSYLPSSQ 229
Query: 233 ISVSNPGAG---SPAPASPPPLAVPG--TEGRPEPV--AMRGPQAAAPPASPEP 279
S S P G S A PPP A PG T + EP+ + A+PEP
Sbjct: 230 ASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283
Score = 32.7 bits (73), Expect = 1.2
Identities = 31/138 (22%), Positives = 45/138 (32%), Gaps = 9/138 (6%)
Query: 147 PEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQV------- 199
P PPV P ++ PP+ P ++ PS A PP +
Sbjct: 558 PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617
Query: 200 VQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPP--LAVPGTE 257
V P P LS+ T+A + ++ S P P P L P +
Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677
Query: 258 GRPEPVAMRGPQAAAPPA 275
G P P +A P+
Sbjct: 678 GSAPPTTYHPPLQSAGPS 695
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 49.7 bits (117), Expect = 1e-05
Identities = 75/291 (25%), Positives = 96/291 (32%), Gaps = 53/291 (18%)
Query: 10 TPAPEAPHPPQLAPPEEQGLLF------QEETIDLGGDEFGSEENETASEGSSPLADKLN 63
TP+P AP P APP Q L + T LG + + S SPLA
Sbjct: 297 TPSPSAPPSPS-APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 64 EH----MMESVLISDSPNSEGDAGDLGRVRDEAEPG-------GEGDPGPEPAG----TP 108
+ + + SP + L +A P P P +P
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 109 SPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAP 168
S P AP S AP P S P PP P P+ AP
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------AP 469
Query: 169 PASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFT 228
P Q+ K P + + TPP PSP S F G F+
Sbjct: 470 PL-------QLAKPPP---QAPPALATPPLQALPSPPAS-FPGQAP------------FS 506
Query: 229 TSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
SA + +S +P P +PP LA P + P P A QA P +P P
Sbjct: 507 PSASLPMSP--LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555
Score = 46.6 bits (109), Expect = 8e-05
Identities = 48/184 (26%), Positives = 61/184 (33%), Gaps = 24/184 (13%)
Query: 102 PEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCT 161
P P+ PS P A +S G+P A S P PP P P
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALA 362
Query: 162 IFSQRAPPA--SGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSL 219
+ +APP+ + P SP A P PSP + F A+
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS---- 418
Query: 220 ASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAM--RGPQAAAPPASP 277
+P A P+ A PP LA P + P P A P A PP +P
Sbjct: 419 --------------PPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 278 EPFA 281
P A
Sbjct: 464 PPLA 467
Score = 41.6 bits (96), Expect = 0.003
Identities = 65/288 (22%), Positives = 97/288 (33%), Gaps = 56/288 (19%)
Query: 4 AGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLN 63
+G GE P + P ++ P + + G +EE T + G + A K +
Sbjct: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE--TVARGKATEAPKRS 145
Query: 64 EHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSP----------SGE 113
+ + P + + R R A G P P P+ P P S
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMAR-RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS 204
Query: 114 ADGDCAPEDAA---PSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPA 170
P AA PS+GG ++ A+R + S +A P P ++ P A
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSL--SSSATPLSSP------------ARSGPSA 250
Query: 171 SGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTS 230
G P+ PS A PPQV P + G ++S
Sbjct: 251 RGT---PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP------------- 294
Query: 231 AFISVSNPGAGSPAPASPP-PLAVPGTEGRPEPVAMRGPQAAAPPASP 277
+P+P++PP P A P + P P A QA SP
Sbjct: 295 ---------LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333
Score = 35.8 bits (81), Expect = 0.15
Identities = 60/222 (27%), Positives = 85/222 (38%), Gaps = 38/222 (17%)
Query: 78 SEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPS-GEADGDCAPEDAAPSSGGAPRQDAA 136
S G GR PG G G + + + G+A AP+ +A S+G R+D +
Sbjct: 101 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE--APKRSALSAGA--RRDTS 156
Query: 137 REVPGSEA---ARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
PG+ + AR + +P ++ PP G S ASE S
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP--------RKSVSSASEHST 208
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGA-GSP-APASP--- 248
P + PS AS SL+S S T + + S P A G+P APA P
Sbjct: 209 TEPSPAARRRPSAGGGL-QRPASRSLSS----SATPLSSPARSGPSARGTPRAPAHPSQP 263
Query: 249 ---------PPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
PP P R + GP +++P A+P P A
Sbjct: 264 KPKGLQALRPPQVTPP---RKDAAPALGPLSSSPLATPSPSA 302
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 11/195 (5%)
Query: 94 PGGEGDPGPEPAGTPSPS--GEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEP 151
PGG P P P P P G A G + + P S +P + P A ++ P
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 152 PVAEPVPVC-TIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQ-PSPSLSTF 209
P PV +I + PP +P + +P +S+A PP P P +
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 210 FGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGR------PEPV 263
G+ + S +T S G P P+ PP V GR P PV
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 264 AMRGPQAAAPPASPE 278
+ G + A PA+P+
Sbjct: 386 SRNGSTSRALPATPQ 400
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 11/195 (5%)
Query: 94 PGGEGDPGPEPAGTPSPS--GEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEP 151
PGG P P P P P G A G + + P S +P + P A ++ P
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 152 PVAEPVPVC-TIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQ-PSPSLSTF 209
P PV +I + PP +P + +P +S+A PP P P +
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 210 FGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGR------PEPV 263
G+ + S +T S G P P+ PP V GR P PV
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 264 AMRGPQAAAPPASPE 278
+ G + A PA+P+
Sbjct: 386 SRNGSTSRALPATPQ 400
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/221 (24%), Positives = 86/221 (38%), Gaps = 21/221 (9%)
Query: 2 EDAGGGEETPAPEAPHPPQLAPPEEQGLL--------FQEETIDLGGDEFGSE---ENET 50
+DA GE P E+ PP+ PP G++ EE L D+ + E E
Sbjct: 2146 KDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEP 2205
Query: 51 ASEGSSPLADKLNEHMMESVLISDSPNSEGDAG-DLGRVRDEAEPGGEGDPGPEPAGTPS 109
G L L + + + + D+ + V E P G GD G E G P+
Sbjct: 2206 EPSGEPKLDVALEAAVEAETVPEERARGDPDSSVEPAPVPPEQRPLGSGDQGAEAEGPPA 2265
Query: 110 -----PSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFS 164
P G A A AA +G +A+R +E +P AEP P T +
Sbjct: 2266 ASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAAEPKP--TAEA 2323
Query: 165 QRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPS 205
+AP + +M ++ + A+++ PP + +P+
Sbjct: 2324 PKAPRV--EEIPQRMTRNRAQMLANQSKQGPPPSEKECAPT 2362
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 7/198 (3%)
Query: 86 GRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAA 145
G + A+P G P + GT P + G P P Q E P SE
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 146 RPE--QEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPS 203
P+ +PP P PP G + + P ++A T V QP
Sbjct: 387 GPKALAQPPGVGKTPAQQP-GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 204 PSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRP--E 261
P + A + S + P P PA PPP PG+ P +
Sbjct: 446 PG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP-QQPGSAKPPSQQ 503
Query: 262 PVAMRGPQAAAPPASPEP 279
P + + P PA P P
Sbjct: 504 PGSTKPPPQQPGPAKPSP 521
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/225 (24%), Positives = 75/225 (33%), Gaps = 47/225 (20%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDA--------- 123
S+ P + A G + A+ G P + GTP P + G +P A
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 124 APSSGGAPRQDAAREVPGSEAAR-------PEQEPPVAEPVPVCTIFSQRAPPASGDGFE 176
P G P Q A PG +A+ P Q P A+P P Q+ PA +
Sbjct: 443 QPGPGKIPAQQAG---PGKTSAQQTGPTKPPSQLPGPAKPPP------QQPGPAKPPPQQ 493
Query: 177 PQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVS 236
P K PS S + PPQ P+ G T
Sbjct: 494 PGSAKPPS---QQPGSTKPPPQQPGPAKPSPQQPGSTKPPS------------------Q 532
Query: 237 NPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
PG+ P+ P P A P + +PV+ G P + P A
Sbjct: 533 QPGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/260 (23%), Positives = 87/260 (33%), Gaps = 51/260 (19%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS-SPLADKLNEH 65
G E P+ E P P LA P G ++ G + T G+ PLA +
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQP--------GPAKPPTQQVGTPKPLAQQPG-- 426
Query: 66 MMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAP 125
++S + P ++ G + A+ G G + G P + G P P
Sbjct: 427 -LQSPAKAPGP-TKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484
Query: 126 SSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSF 185
P Q PGS A P Q+P +P P Q+ PA +P K PS
Sbjct: 485 GPAKPPPQQ-----PGS-AKPPSQQPGSTKPPP------QQPGPAKPSPQQPGSTKPPSQ 532
Query: 186 GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP-- 243
S + P +PS ST VS G+G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQST------------------------KPVSQTGSGKPLQ 568
Query: 244 APASPPPLAVPGTEGRPEPV 263
P P P ++G P+ +
Sbjct: 569 PPTVSPSAKQPPSQGLPKTI 588
Score = 38.5 bits (88), Expect = 0.023
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 47/226 (20%)
Query: 98 GDPGPEPAGTPSP----------SGEADGDCAPEDAAPSSGGAPRQDAAR---------- 137
GD P P+ +P P S + P+ +P AP+QD ++
Sbjct: 648 GDLAPVPS-SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 138 ----EVPGSEAARPEQEP-------PVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG 186
+ GS +A+ +Q P P P +AP A +P+MVK P+
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK-PTTD 765
Query: 187 GASEASARTPPQV----------VQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVS 236
S +SA T P + + +P L T + S + F + A +
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA---IP 822
Query: 237 NPGAGSPAPASPPPLAVPGTEGRPEPVAMR-GPQAAAPPASPEPFA 281
P + S + P P + + + +PV + P+ A SP+P A
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Score = 33.5 bits (75), Expect = 0.73
Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 26/176 (14%)
Query: 97 EGDPGPEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAE 155
+G +P +A +P+ DA P G+P R G P+Q P E
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 156 PVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAA 215
S+R G S A ++ TP + V FG A+
Sbjct: 901 Q-------SRRFSLNLG-----------SITDAPKSQPTTPQETVT-----GKLFGFGAS 937
Query: 216 SHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAA 271
S AS+ + S S PGA P +P P P ++G P+ P A
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--PMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 7/198 (3%)
Query: 86 GRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAA 145
G + A+P G P + GT P + G P P Q E P SE
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 146 RPE--QEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPS 203
P+ +PP P PP G + + P ++A T V QP
Sbjct: 387 GPKALAQPPGVGKTPAQQP-GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 204 PSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRP--E 261
P + A + S + P P PA PPP PG+ P +
Sbjct: 446 PG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP-QQPGSAKPPSQQ 503
Query: 262 PVAMRGPQAAAPPASPEP 279
P + + P PA P P
Sbjct: 504 PGSTKPPPQQPGPAKPSP 521
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/225 (24%), Positives = 75/225 (33%), Gaps = 47/225 (20%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDA--------- 123
S+ P + A G + A+ G P + GTP P + G +P A
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 124 APSSGGAPRQDAAREVPGSEAAR-------PEQEPPVAEPVPVCTIFSQRAPPASGDGFE 176
P G P Q A PG +A+ P Q P A+P P Q+ PA +
Sbjct: 443 QPGPGKIPAQQAG---PGKTSAQQTGPTKPPSQLPGPAKPPP------QQPGPAKPPPQQ 493
Query: 177 PQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVS 236
P K PS S + PPQ P+ G T
Sbjct: 494 PGSAKPPS---QQPGSTKPPPQQPGPAKPSPQQPGSTKPPS------------------Q 532
Query: 237 NPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
PG+ P+ P P A P + +PV+ G P + P A
Sbjct: 533 QPGSAKPSAQQPSP-AKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/260 (23%), Positives = 87/260 (33%), Gaps = 51/260 (19%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS-SPLADKLNEH 65
G E P+ E P P LA P G ++ G + T G+ PLA +
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQP--------GPAKPPTQQVGTPKPLAQQPG-- 426
Query: 66 MMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAP 125
++S + P ++ G + A+ G G + G P + G P P
Sbjct: 427 -LQSPAKAPGP-TKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484
Query: 126 SSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSF 185
P Q PGS A P Q+P +P P Q+ PA +P K PS
Sbjct: 485 GPAKPPPQQ-----PGS-AKPPSQQPGSTKPPP------QQPGPAKPSPQQPGSTKPPSQ 532
Query: 186 GGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSP-- 243
S + P +PS ST VS G+G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQST------------------------KPVSQTGSGKPLQ 568
Query: 244 APASPPPLAVPGTEGRPEPV 263
P P P ++G P+ +
Sbjct: 569 PPTVSPSAKQPPSQGLPKTI 588
Score = 38.5 bits (88), Expect = 0.023
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 47/226 (20%)
Query: 98 GDPGPEPAGTPSP----------SGEADGDCAPEDAAPSSGGAPRQDAAR---------- 137
GD P P+ +P P S + P+ +P AP+QD ++
Sbjct: 648 GDLAPVPS-SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 138 ----EVPGSEAARPEQEP-------PVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG 186
+ GS +A+ +Q P P P +AP A +P+MVK P+
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK-PTTD 765
Query: 187 GASEASARTPPQV----------VQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVS 236
S +SA T P + + +P L T + S + F + A +
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA---IP 822
Query: 237 NPGAGSPAPASPPPLAVPGTEGRPEPVAMR-GPQAAAPPASPEPFA 281
P + S + P P + + + +PV + P+ A SP+P A
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Score = 33.5 bits (75), Expect = 0.73
Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 26/176 (14%)
Query: 97 EGDPGPEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAE 155
+G +P +A +P+ DA P G+P R G P+Q P E
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 156 PVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAA 215
S+R G S A ++ TP + V FG A+
Sbjct: 901 Q-------SRRFSLNLG-----------SITDAPKSQPTTPQETVT-----GKLFGFGAS 937
Query: 216 SHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAA 271
S AS+ + S S PGA P +P P P ++G P+ P A
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--PMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/214 (26%), Positives = 73/214 (34%), Gaps = 32/214 (14%)
Query: 72 ISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGA 130
I P +G G+ G + +PG G PGP+ P G P G P D P G
Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196
Query: 131 PR-QDAAREVPG--SEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG- 186
PR QD A+ G E +P P E P + + PA G E + + G
Sbjct: 1197 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL--GKRGPAGSPGSEGRQGGKGAKGD 1254
Query: 187 -GASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG----AG 241
GA A +T P G + D S PG AG
Sbjct: 1255 PGAIGAPGKTGP------------VGPAGPAGKPGPDGLRGLPGSVG-QQGRPGATGQAG 1301
Query: 242 SPAPASPPPL-------AVPGTEGRPEPVAMRGP 268
P P PP L G +G P + + GP
Sbjct: 1302 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1335
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/134 (27%), Positives = 54/134 (40%), Gaps = 16/134 (11%)
Query: 1 MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEF--GSEEN---------- 48
+E GG E P + PH Q +P ++ L + + + + G EE
Sbjct: 226 LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPL 285
Query: 49 ETASEGSSPLADKLNEHMM--ESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAG 106
E A+ G L + E + +L+ P EG AG +G + PG GDPG G
Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER--G 343
Query: 107 TPSPSGEADGDCAP 120
P +G D AP
Sbjct: 344 PPGRAGLPGSDGAP 357
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/329 (21%), Positives = 93/329 (28%), Gaps = 64/329 (19%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
GE P E HP PP EQGL G+ E P
Sbjct: 848 GETGPMGERGHPGPPGPPGEQGLP-------------GTAGKEGTKGDPGP--------- 885
Query: 67 MESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG----------PEPAGTPSPSGEA-D 115
+P +G AG G + PG G PG P PAG+P G A
Sbjct: 886 ------PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939
Query: 116 GDCAPEDAAPSSGGAPRQDAAREVPGSE-----AARPEQEPPVAEPVPVCTIFSQRAPPA 170
G P G P + VPG + R + PV P P P
Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA------GPPGV 993
Query: 171 SGDGFEPQMVKSP----SFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDS 226
+G+ + V P + G E PP + P D F +
Sbjct: 994 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1053
Query: 227 FTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAV 286
+ P P P G G P+ GP PA P
Sbjct: 1054 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN-------- 1105
Query: 287 FAGSDDPFATALSMSEMDRRNDAWLPGEA 315
G+D P + + + PGE+
Sbjct: 1106 --GADGPQGPPGGVGNLGPPGEKGEPGES 1132
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 7/87 (8%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQ 133
+G G LG + PG +G PG P P G P GE P P S G P
Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606
Query: 134 DAAREVPGSEAARPEQEP--PVAEPVP 158
PG++ + P P+ P P
Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGP 633
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGE--ADGDCAPEDAAPSSG-GAP 131
P +G+ GD G + PG +G+ G P +G P G G P+ A ++G G P
Sbjct: 1336 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1395
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPV 159
+ + + P P + V +P+P+
Sbjct: 1396 KGEKGVQGPPGHPGPPGE---VIQPLPI 1420
Score = 33.9 bits (76), Expect = 0.56
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 2/73 (2%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP--EDAAPSSGGAPRQDAA 136
+G+ GD+G + PG G GP A P G+ P E P G+P
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140
Query: 137 REVPGSEAARPEQ 149
V G R E+
Sbjct: 1141 PGVKGPRGERGEK 1153
Score = 33.5 bits (75), Expect = 0.73
Identities = 52/210 (24%), Positives = 68/210 (32%), Gaps = 44/210 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P G G++G PG G GP+ AG P GE P G P +
Sbjct: 817 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER--------GHPGPPGPPGEQ 868
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
G E + + PP A + PA GF + + GG
Sbjct: 869 GLPGTAGKEGTKGDPGPPGA---------PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919
Query: 195 TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLA-- 252
P P P+ S G+ A+ S + P G P P PP A
Sbjct: 920 GPSG--PPGPAGSP--GERGAAGSGG-------------PIGPP--GRPGPQGPPGAAGE 960
Query: 253 --VPGTEGRPEPV---AMRGPQAAAPPASP 277
VPG +G P ++GP PA P
Sbjct: 961 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 990
Score = 33.5 bits (75), Expect = 0.73
Identities = 69/288 (23%), Positives = 87/288 (30%), Gaps = 66/288 (22%)
Query: 6 GGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS-SPLADKLNE 64
G + P P P PP E G Q+ G E+ E GS P +
Sbjct: 1175 GPKGNPGPVG-FPGDPGPPGEGGPRGQD-----GAKGDRGEDGEPGQPGSPGPTGENGPP 1228
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAA 124
+ + SP SEG G G + +PG G PG G P+G A
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGA---KGDPGAIGAPG--KTGPVGPAGPA---------- 1273
Query: 125 PSSGGAPRQDAAREVPGS--EAARPEQEPPVAEPVPVCTIFSQRAPP----------ASG 172
G P D R +PGS + RP P PV PP A G
Sbjct: 1274 ----GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV-------GPPGLPGLRGDAGAKG 1322
Query: 173 DGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF 232
+ P ++ G Q SP G AS +
Sbjct: 1323 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI------------- 1369
Query: 233 ISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAA-APPASPEP 279
G G P P P P G +G P +G + PP P P
Sbjct: 1370 ------GPGGP-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/99 (27%), Positives = 35/99 (35%), Gaps = 23/99 (23%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTPSPSG--------------EA 114
P +GD G G + PG G+ GPE P G P P G
Sbjct: 658 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 717
Query: 115 DGDCAPEDAA--PSSGGAPRQDAAREVPGSEAARPEQEP 151
G P+ + P GA + AR + G R E+ P
Sbjct: 718 PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 756
Score = 30.4 bits (67), Expect = 6.1
Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 7/89 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADGDCAPE--DAAPSSGG 129
P +G GD G PG +G+ G + P G P SG G P+ P G
Sbjct: 481 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR-GLLGPKGPPGIPGPPG 539
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVP 158
D + GS + E PP + P
Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPGQQGTP 568
Score = 30.4 bits (67), Expect = 6.1
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPEDAAPSSG--G 129
P +G+ GD G + PG G G P G P P G D P+ S G G
Sbjct: 499 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSLGPQG 557
Query: 130 APRQDAAREVPGSE 143
P + PG++
Sbjct: 558 EPGPPGQQGTPGTQ 571
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/214 (26%), Positives = 73/214 (34%), Gaps = 32/214 (14%)
Query: 72 ISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGA 130
I P +G G+ G + +PG G PGP+ P G P G P D P G
Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175
Query: 131 PR-QDAAREVPG--SEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG- 186
PR QD A+ G E +P P E P + + PA G E + + G
Sbjct: 1176 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL--GKRGPAGSPGSEGRQGGKGAKGD 1233
Query: 187 -GASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG----AG 241
GA A +T P G + D S PG AG
Sbjct: 1234 PGAIGAPGKTGP------------VGPAGPAGKPGPDGLRGLPGSVG-QQGRPGATGQAG 1280
Query: 242 SPAPASPPPL-------AVPGTEGRPEPVAMRGP 268
P P PP L G +G P + + GP
Sbjct: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1314
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 13/122 (10%)
Query: 1 MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLAD 60
+E GG E P + PH Q +P ++ L + + E A+ G L
Sbjct: 226 LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQN---------QEPQSQAAHGPRGLKG 276
Query: 61 KLNEHMM--ESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDC 118
+ E + +L+ P EG AG +G + PG GDPG G P +G D
Sbjct: 277 EKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDG 334
Query: 119 AP 120
AP
Sbjct: 335 AP 336
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/329 (21%), Positives = 93/329 (28%), Gaps = 64/329 (19%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
GE P E HP PP EQGL G+ E P
Sbjct: 827 GETGPMGERGHPGPPGPPGEQGLP-------------GTAGKEGTKGDPGP--------- 864
Query: 67 MESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG----------PEPAGTPSPSGEA-D 115
+P +G AG G + PG G PG P PAG+P G A
Sbjct: 865 ------PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918
Query: 116 GDCAPEDAAPSSGGAPRQDAAREVPGSE-----AARPEQEPPVAEPVPVCTIFSQRAPPA 170
G P G P + VPG + R + PV P P P
Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA------GPPGV 972
Query: 171 SGDGFEPQMVKSP----SFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDS 226
+G+ + V P + G E PP + P D F +
Sbjct: 973 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1032
Query: 227 FTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAV 286
+ P P P G G P+ GP PA P
Sbjct: 1033 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN-------- 1084
Query: 287 FAGSDDPFATALSMSEMDRRNDAWLPGEA 315
G+D P + + + PGE+
Sbjct: 1085 --GADGPQGPPGGVGNLGPPGEKGEPGES 1111
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 7/87 (8%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQ 133
+G G LG + PG +G PG P P G P GE P P S G P
Sbjct: 526 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585
Query: 134 DAAREVPGSEAARPEQEP--PVAEPVP 158
PG++ + P P+ P P
Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGP 612
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGE--ADGDCAPEDAAPSSG-GAP 131
P +G+ GD G + PG +G+ G P +G P G G P+ A ++G G P
Sbjct: 1315 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1374
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPV 159
+ + + P P + V +P+P+
Sbjct: 1375 KGEKGVQGPPGHPGPPGE---VIQPLPI 1399
Score = 33.9 bits (76), Expect = 0.56
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 2/73 (2%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP--EDAAPSSGGAPRQDAA 136
+G+ GD+G + PG G GP A P G+ P E P G+P
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119
Query: 137 REVPGSEAARPEQ 149
V G R E+
Sbjct: 1120 PGVKGPRGERGEK 1132
Score = 33.5 bits (75), Expect = 0.73
Identities = 52/210 (24%), Positives = 68/210 (32%), Gaps = 44/210 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P G G++G PG G GP+ AG P GE P G P +
Sbjct: 796 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER--------GHPGPPGPPGEQ 847
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
G E + + PP A + PA GF + + GG
Sbjct: 848 GLPGTAGKEGTKGDPGPPGA---------PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898
Query: 195 TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLA-- 252
P P P+ S G+ A+ S + P G P P PP A
Sbjct: 899 GPSG--PPGPAGSP--GERGAAGSGG-------------PIGPP--GRPGPQGPPGAAGE 939
Query: 253 --VPGTEGRPEPV---AMRGPQAAAPPASP 277
VPG +G P ++GP PA P
Sbjct: 940 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969
Score = 33.5 bits (75), Expect = 0.73
Identities = 69/288 (23%), Positives = 87/288 (30%), Gaps = 66/288 (22%)
Query: 6 GGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS-SPLADKLNE 64
G + P P P PP E G Q+ G E+ E GS P +
Sbjct: 1154 GPKGNPGPVG-FPGDPGPPGEGGPRGQD-----GAKGDRGEDGEPGQPGSPGPTGENGPP 1207
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAA 124
+ + SP SEG G G + +PG G PG G P+G A
Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGA---KGDPGAIGAPG--KTGPVGPAGPA---------- 1252
Query: 125 PSSGGAPRQDAAREVPGS--EAARPEQEPPVAEPVPVCTIFSQRAPP----------ASG 172
G P D R +PGS + RP P PV PP A G
Sbjct: 1253 ----GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV-------GPPGLPGLRGDAGAKG 1301
Query: 173 DGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF 232
+ P ++ G Q SP G AS +
Sbjct: 1302 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI------------- 1348
Query: 233 ISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAA-APPASPEP 279
G G P P P P G +G P +G + PP P P
Sbjct: 1349 ------GPGGP-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1389
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/99 (27%), Positives = 35/99 (35%), Gaps = 23/99 (23%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTPSPSG--------------EA 114
P +GD G G + PG G+ GPE P G P P G
Sbjct: 637 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 696
Query: 115 DGDCAPEDAA--PSSGGAPRQDAAREVPGSEAARPEQEP 151
G P+ + P GA + AR + G R E+ P
Sbjct: 697 PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 735
Score = 30.4 bits (67), Expect = 6.1
Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 7/89 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADGDCAPE--DAAPSSGG 129
P +G GD G PG +G+ G + P G P SG G P+ P G
Sbjct: 460 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR-GLLGPKGPPGIPGPPG 518
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVP 158
D + GS + E PP + P
Sbjct: 519 VRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547
Score = 30.4 bits (67), Expect = 6.1
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPEDAAPSSG--G 129
P +G+ GD G + PG G G P G P P G D P+ S G G
Sbjct: 478 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSLGPQG 536
Query: 130 APRQDAAREVPGSE 143
P + PG++
Sbjct: 537 EPGPPGQQGTPGTQ 550
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/214 (26%), Positives = 73/214 (34%), Gaps = 32/214 (14%)
Query: 72 ISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGA 130
I P +G G+ G + +PG G PGP+ P G P G P D P G
Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282
Query: 131 PR-QDAAREVPG--SEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFG- 186
PR QD A+ G E +P P E P + + PA G E + + G
Sbjct: 1283 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL--GKRGPAGSPGSEGRQGGKGAKGD 1340
Query: 187 -GASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPG----AG 241
GA A +T P G + D S PG AG
Sbjct: 1341 PGAIGAPGKTGP------------VGPAGPAGKPGPDGLRGLPGSVG-QQGRPGATGQAG 1387
Query: 242 SPAPASPPPL-------AVPGTEGRPEPVAMRGP 268
P P PP L G +G P + + GP
Sbjct: 1388 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1421
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/329 (21%), Positives = 93/329 (28%), Gaps = 64/329 (19%)
Query: 7 GEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHM 66
GE P E HP PP EQGL G+ E P
Sbjct: 934 GETGPMGERGHPGPPGPPGEQGLP-------------GTAGKEGTKGDPGP--------- 971
Query: 67 MESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPG----------PEPAGTPSPSGEA-D 115
+P +G AG G + PG G PG P PAG+P G A
Sbjct: 972 ------PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025
Query: 116 GDCAPEDAAPSSGGAPRQDAAREVPGSE-----AARPEQEPPVAEPVPVCTIFSQRAPPA 170
G P G P + VPG + R + PV P P P
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA------GPPGV 1079
Query: 171 SGDGFEPQMVKSP----SFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDS 226
+G+ + V P + G E PP + P D F +
Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1139
Query: 227 FTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAV 286
+ P P P G G P+ GP PA P
Sbjct: 1140 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN-------- 1191
Query: 287 FAGSDDPFATALSMSEMDRRNDAWLPGEA 315
G+D P + + + PGE+
Sbjct: 1192 --GADGPQGPPGGVGNLGPPGEKGEPGES 1218
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 7/87 (8%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPE-DAAPSSGGAPRQ 133
+G G LG + PG +G PG P P G P GE P P S G P
Sbjct: 633 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692
Query: 134 DAAREVPGSEAARPEQEP--PVAEPVP 158
PG++ + P P+ P P
Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGP 719
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG-PEPAGTPSPSGE--ADGDCAPEDAAPSSG-GAP 131
P +G+ GD G + PG +G+ G P +G P G G P+ A ++G G P
Sbjct: 1422 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1481
Query: 132 RQDAAREVPGSEAARPEQEPPVAEPVPV 159
+ + + P P + V +P+P+
Sbjct: 1482 KGEKGVQGPPGHPGPPGE---VIQPLPI 1506
Score = 33.9 bits (76), Expect = 0.56
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 2/73 (2%)
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP--EDAAPSSGGAPRQDAA 136
+G+ GD+G + PG G GP A P G+ P E P G+P
Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1226
Query: 137 REVPGSEAARPEQ 149
V G R E+
Sbjct: 1227 PGVKGPRGERGEK 1239
Score = 33.5 bits (75), Expect = 0.73
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 70 VLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAP 120
+L+ P EG AG +G + PG GDPG G P +G D AP
Sbjct: 395 MLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDGAP 443
Score = 33.5 bits (75), Expect = 0.73
Identities = 52/210 (24%), Positives = 68/210 (32%), Gaps = 44/210 (20%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-PAGTPSPSGEADGDCAPEDAAPSSGGAPRQD 134
P G G++G PG G GP+ AG P GE P G P +
Sbjct: 903 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER--------GHPGPPGPPGEQ 954
Query: 135 AAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASAR 194
G E + + PP A + PA GF + + GG
Sbjct: 955 GLPGTAGKEGTKGDPGPPGA---------PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005
Query: 195 TPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLA-- 252
P P P+ S G+ A+ S + P G P P PP A
Sbjct: 1006 GPSG--PPGPAGSP--GERGAAGSGG-------------PIGPP--GRPGPQGPPGAAGE 1046
Query: 253 --VPGTEGRPEPV---AMRGPQAAAPPASP 277
VPG +G P ++GP PA P
Sbjct: 1047 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 1076
Score = 33.5 bits (75), Expect = 0.73
Identities = 69/288 (23%), Positives = 87/288 (30%), Gaps = 66/288 (22%)
Query: 6 GGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS-SPLADKLNE 64
G + P P P PP E G Q+ G E+ E GS P +
Sbjct: 1261 GPKGNPGPVG-FPGDPGPPGEGGPRGQD-----GAKGDRGEDGEPGQPGSPGPTGENGPP 1314
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAA 124
+ + SP SEG G G + +PG G PG G P+G A
Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGA---KGDPGAIGAPG--KTGPVGPAGPA---------- 1359
Query: 125 PSSGGAPRQDAAREVPGS--EAARPEQEPPVAEPVPVCTIFSQRAPP----------ASG 172
G P D R +PGS + RP P PV PP A G
Sbjct: 1360 ----GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV-------GPPGLPGLRGDAGAKG 1408
Query: 173 DGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF 232
+ P ++ G Q SP G AS +
Sbjct: 1409 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI------------- 1455
Query: 233 ISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAA-APPASPEP 279
G G P P P P G +G P +G + PP P P
Sbjct: 1456 ------GPGGP-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1496
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/99 (27%), Positives = 35/99 (35%), Gaps = 23/99 (23%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTPSPSG--------------EA 114
P +GD G G + PG G+ GPE P G P P G
Sbjct: 744 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 803
Query: 115 DGDCAPEDAA--PSSGGAPRQDAAREVPGSEAARPEQEP 151
G P+ + P GA + AR + G R E+ P
Sbjct: 804 PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 842
Score = 30.4 bits (67), Expect = 6.1
Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 7/89 (7%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADGDCAPE--DAAPSSGG 129
P +G GD G PG +G+ G + P G P SG G P+ P G
Sbjct: 567 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR-GLLGPKGPPGIPGPPG 625
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVP 158
D + GS + E PP + P
Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPGQQGTP 654
Score = 30.4 bits (67), Expect = 6.1
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSGEADGDCAPEDAAPSSG--G 129
P +G+ GD G + PG G G P G P P G D P+ S G G
Sbjct: 585 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSLGPQG 643
Query: 130 APRQDAAREVPGSE 143
P + PG++
Sbjct: 644 EPGPPGQQGTPGTQ 657
Score = 30.0 bits (66), Expect = 8.0
Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 2/55 (3%)
Query: 72 ISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAG--TPSPSGEADGDCAPEDAA 124
I +P GD G+ G PG +G PGP P G GD P AA
Sbjct: 415 IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA 469
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.5 bits (114), Expect = 2e-05
Identities = 53/193 (27%), Positives = 70/193 (36%), Gaps = 18/193 (9%)
Query: 100 PGPEPAGTP-SPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVP 158
P PA P SPS P AAP P A+ + S P+ PP+A P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Query: 159 VCTIFSQRAPPASGDGFEP------------QMVKSPSFGGASEASARTPPQVVQPSPSL 206
+PP S P Q+ SP A+ PPQ P+L
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA---PPAL 792
Query: 207 STFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMR 266
+T S + F+ SA + +S +P P +PP LA P + P P A
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSP--LATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 267 GPQAAAPPASPEP 279
QA P +P P
Sbjct: 851 TLQAPRRPPTPGP 863
Score = 48.1 bits (113), Expect = 3e-05
Identities = 52/191 (27%), Positives = 64/191 (33%), Gaps = 20/191 (10%)
Query: 102 PEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCT 161
P P TP P + P A P+ P Q A P Q PP P
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP--- 629
Query: 162 IFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTA------- 214
+ + +PPAS P SP A P PSP + F A
Sbjct: 630 LQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 215 ------ASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAM--R 266
A SLA+ + +P A +P P +PPPLA P + P P A
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQAPPPLAAPPLQVPPSPPASPPM 747
Query: 267 GPQAAAPPASP 277
P A PP P
Sbjct: 748 SPSATPPPRVP 758
Score = 44.3 bits (103), Expect = 4e-04
Identities = 81/324 (25%), Positives = 114/324 (35%), Gaps = 63/324 (19%)
Query: 7 GEETPAPEA-PHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEH 65
G PAP A P PP P + E + E A+ L
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVS----------SASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 66 MMESVLISDSP-NSEGDAGDLGRVRDEAEPGGEGDPGPE-------PAGTPSPSGEADGD 117
S+ S +P +S +G R A P P P+ P TP P +A
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQALRPPQVTP-PRKDAAPA 295
Query: 118 CAPEDAAPSSGGAPRQDAAREVPGSE-AARP-----EQEPPVAEPVPVCTIFSQRAPPAS 171
P ++P + +P AR VP + AA P PP+A P+P+ APP+
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL-------APPSP 348
Query: 172 GDGFEPQMVKSPSFGGASEA--SARTPPQVVQPS---------------PSLSTFFGDTA 214
Q + SP S+A S TPP PS PSL A
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 215 ASHSLASDFFDSFT---TSAFISVS---------NPGAGSPAPASPPPLAVPGTEGRPEP 262
S A+ S T T +F+++S +P + P PPL P + P
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 263 VAMRGPQAAAPPASPEPFAHIQAV 286
+ A +P +SP +QA+
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQAL 492
Score = 43.1 bits (100), Expect = 0.001
Identities = 67/293 (22%), Positives = 100/293 (34%), Gaps = 39/293 (13%)
Query: 4 AGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLN 63
+G GE P + P ++ P + + G +EE T + G + A K +
Sbjct: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE--TVARGKATEAPKRS 154
Query: 64 EHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSP----------SGE 113
+ + P + + R R A G P P P+ P P S
Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMAR-RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS 213
Query: 114 ADGDCAPEDAA---PSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPA 170
P AA PS+GG ++ A+R + S +A P P ++ P A
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSL--SSSATPLSSP------------ARSGPSA 259
Query: 171 SGDGFEPQMVKSPSFGGASEASARTPPQVVQP----SPSLSTFFGDTAASHSLASDFFDS 226
G P+ PS A PPQV P +P+L A+ S +
Sbjct: 260 RGT---PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 227 FTTSAFISVSNPGAGSPAP--ASPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
+ P P+P A+P PLA P P + P A P +P
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/197 (25%), Positives = 64/197 (32%), Gaps = 11/197 (5%)
Query: 91 EAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQE 150
+A P P P TPSP A S +P A P S P
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 151 PPVAEPVPVCTIFSQ--RAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLST 208
PP P + Q +PPAS P M S + + PP V PSP S
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 209 FFGDTAASHSLASDFFDS----FTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVA 264
+A + S S+ P P +PP LA P + P P A
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 265 MRGPQAAAPPASPEPFA 281
QA P++ P +
Sbjct: 806 SFPGQAPFSPSASLPMS 822
Score = 40.0 bits (92), Expect = 0.008
Identities = 46/192 (23%), Positives = 65/192 (33%), Gaps = 14/192 (7%)
Query: 100 PGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPV 159
P + A P + + P + +P E P S A P Q PP P+
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 160 CTIFS-QRAPPASGDGFEPQMVKSPSFGGASEASARTP-PQVVQPSPSLSTFFGDTAASH 217
+ S +P A+ P + P A P + PSP + A H
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP----NALAVH 659
Query: 218 SLASDFFDSFTTSAFISVSNPG------AGSPAPASPPPLAVPGTEGRPEPVAM--RGPQ 269
L + F + S P + +P +PP LA P + P P A P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 270 AAAPPASPEPFA 281
A PP +P P A
Sbjct: 720 ATPPPQAPPPLA 731
Score = 33.9 bits (76), Expect = 0.56
Identities = 60/260 (23%), Positives = 86/260 (33%), Gaps = 68/260 (26%)
Query: 52 SEGSSPLADKLNEHMMESV--LISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPS 109
S SPL+ L H ++++ L S SP + + + + ++ P PA +
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP-PASLTT 532
Query: 110 PSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPP 169
P E AP +S AP E P A P Q PP P PP
Sbjct: 533 PPLENLPSLAPPPLQTAS--APLTTPHLETPPCPAPCPLQAPPSPLTTP---------PP 581
Query: 170 ASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTT 229
+ P + +P + + +PP PSP LS
Sbjct: 582 ET-----PSSIATPP--PQAPPALASPPLQGLPSPPLSPL-------------------- 614
Query: 230 SAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVA------MRGPQAAAP---------- 273
+P P +PP LA+P + P P A + P AP
Sbjct: 615 -----------ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663
Query: 274 PASPEPFAHIQAVFAGSDDP 293
P SP P +QA F+ P
Sbjct: 664 PFSPPPSPPVQAPFSPPASP 683
Score = 33.5 bits (75), Expect = 0.73
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 31/206 (15%)
Query: 78 SEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPS-GEADGDCAPEDAAPSSGGAPRQDAA 136
S G GR PG G G + + + G+A AP+ +A S+G R+D +
Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE--APKRSALSAGA--RRDTS 165
Query: 137 REVPGSEA---ARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASA 193
PG+ + AR + +P ++ PP G S ASE S
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP--------RKSVSSASEHST 217
Query: 194 RTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAV 253
P + PS AS SL+S S SPA + P
Sbjct: 218 TEPSPAARRRPSAGGGL-QRPASRSLSS--------------SATPLSSPARSGPSARGT 262
Query: 254 PGTEGRPEPVAMRGPQAAAPPASPEP 279
P P +G QA PP P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPP 288
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 48.5 bits (114), Expect = 2e-05
Identities = 70/287 (24%), Positives = 103/287 (35%), Gaps = 31/287 (10%)
Query: 5 GGGEETPAPEAPHPPQLAPPEEQGLLFQEETI---DLGGDEFGSEENETASEGSSPLADK 61
G E +P A HP PP+ G Q+ T L + G + LA+
Sbjct: 377 GSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEA 436
Query: 62 LNEHMMESVLISDSPNSEGDAGDLG-RVRDEAEPG-----GEGDPGPE-PAGTPSPSGEA 114
N L + +SE A +V EP G G+PGP+ P+ TPSP A
Sbjct: 437 TNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPA 496
Query: 115 DGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGD- 173
E ++P+ G +P VPG E A +P APPAS
Sbjct: 497 PARVKAELSSPTPGSSP-------VPG------ELGLAGALFLPQYVFGPDAAPPASEIL 543
Query: 174 GFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFI 233
++V S GA + + +P G T + +++ +
Sbjct: 544 AKMSELVHSRLQQGAGAGAGGAQTGLFPGAPK-----GATCFECEITFSNVNNYYVHKRL 598
Query: 234 SVSNPGAGSPAPASPPPLAVPGTEGRP--EPVAMRGPQAAAPPASPE 278
S A APA+ P A PG P +P P+++ P + E
Sbjct: 599 YCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGARE 645
Score = 33.1 bits (74), Expect = 0.95
Identities = 41/173 (23%), Positives = 61/173 (35%), Gaps = 14/173 (8%)
Query: 56 SPLADKLNEHMMESVLISDSPNSEGD--AGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGE 113
S D L H++ + ++ P S+G+ + G + P G + P
Sbjct: 357 STTRDILYSHLVTNHMVCQ-PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLAS 415
Query: 114 ADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARP------EQEPPVA-EPVPVCTIFSQR 166
AD AP S G R+ A G A P EPP A + V +
Sbjct: 416 ADLGLAPTP----SPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPE 471
Query: 167 APPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSL 219
A P G G S + S A AR ++ P+P S G+ + +L
Sbjct: 472 AAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGAL 524
Score = 31.6 bits (70), Expect = 2.8
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 8/72 (11%)
Query: 120 PEDAAPSSGGAPRQDAAREVPGSEAAR----PE-QEPPVAEPVPVCTIFSQRAPPASGDG 174
P D PS AP AA PGS R PE QEPP P PP +
Sbjct: 895 PADRGPSPAPAP---AASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS 951
Query: 175 FEPQMVKSPSFG 186
+ + V++PS G
Sbjct: 952 YSDKGVQTPSKG 963
Score = 31.2 bits (69), Expect = 3.6
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 11/70 (15%)
Query: 92 AEPGGEG----DPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPR-QDAAREVPGSEAAR 146
A PG E D GP PA P+ S + P P G P Q+ P S AA
Sbjct: 886 AGPGVEARTPADRGPSPAPAPAASPQ------PGSRGPRDGLGPEPQEPPPGPPPSPAAA 939
Query: 147 PEQEPPVAEP 156
PE PP P
Sbjct: 940 PEAVPPPPAP 949
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 48.1 bits (113), Expect = 3e-05
Identities = 70/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 57 PLADKLNEHMMESVLI--------SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTP 108
PL D NE + S + S S +S G G + PG PGP T
Sbjct: 777 PLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPG---NPFSPGTPISPGPIFPITS 833
Query: 109 SPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAP 168
P + +P + SS +P ++ +P S + PE PVP+ P
Sbjct: 834 PPCHPSPSPFSPISSQVSSNPSPHPTSS-PLPFSSST-PEF------PVPLSQCPWSSLP 885
Query: 169 PASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAAS-HSLASDFFDSF 227
S F P S+ + +P P PS S+F TAA SLAS F +
Sbjct: 886 TTSPPTFSPT---------CSQVTLSSP--FFPPCPSTSSFPSTTAAPLLSLASAFSLAV 934
Query: 228 TTSA---------FISVSNPGAGSPAPASP-PPLAVPGTEGRPEP-VAMRGPQAAAPPAS 276
T A +S S P SP P+ P PP PG + P P A +A+ PPA
Sbjct: 935 MTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVESEASPPPAR 994
Query: 277 PEP 279
P P
Sbjct: 995 PLP 997
Score = 32.0 bits (71), Expect = 2.1
Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 13/116 (11%)
Query: 187 GASEASART--PPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAF-ISVSNPGAGSP 243
G EA+ T P + P P+L D + +S + + +AF S S+PG
Sbjct: 753 GPMEAAEDTLSPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPG---- 808
Query: 244 APASPPPLAVPGTEGRPEPVAMRGPQAAAPPA--SPEPFAHIQAVFAGSDDPFATA 297
P SP PGT P P+ +PP SP PF+ I + + + P T+
Sbjct: 809 TPLSPGNPFSPGTPISPGPIF----PITSPPCHPSPSPFSPISSQVSSNPSPHPTS 860
Score = 30.4 bits (67), Expect = 6.1
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 28/151 (18%)
Query: 166 RAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFD 225
R PP G +P++ G AR +P P S ++ L S +
Sbjct: 23 RPPPPLGTAGQPRL-------GPPPRRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSW-- 73
Query: 226 SFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQA----AAPPASPEPFA 281
S P + +P P PP A PG P P + P+ AP + E A
Sbjct: 74 ----------SLPASPAPDPPDPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAAEDSA 123
Query: 282 HIQ----AVFAGSDDPFATALSMSEMDRRND 308
+ AV GS +P +++ ++RR +
Sbjct: 124 RPELPDSAVGPGSREPLRVPEAVA-LERRRE 153
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 48.1 bits (113), Expect = 3e-05
Identities = 71/294 (24%), Positives = 110/294 (37%), Gaps = 27/294 (9%)
Query: 19 PQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHMMESVLISDSPNS 78
P A +E G + E G++E E + GS+P ADK S S S
Sbjct: 28 PSKANGQENGHVKVNGDASPAAAESGAKE-ELQANGSAPAADKEEPAAAGSGAASPSAAE 86
Query: 79 EGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAARE 138
+G+ A P + P A P A+G+ A AA S+ +D A
Sbjct: 87 KGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA--SAASSTSSPKAEDGATP 144
Query: 139 VPGSEAARPEQEPPVAEPVPVCTIFS-QRAPPASGDGFEPQMV-----KSPSFGG----A 188
P +E + +++ + + FS ++ +G+G E + K + GG A
Sbjct: 145 SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAA 204
Query: 189 SEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASP 248
+EA A + Q P + G+ A+ D ++ A ++ P A A+
Sbjct: 205 AEAGAASGEQAAAPGEEAAA--GEEGAA---GGDPQEAKPQEAAVAPEKPPASDETKAAE 259
Query: 249 PPLAV---PGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALS 299
P V E A P AA P A PE A A +++P A A S
Sbjct: 260 EPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA------APAEEPAAAAAS 307
Score = 34.3 bits (77), Expect = 0.43
Identities = 36/127 (28%), Positives = 51/127 (40%), Gaps = 27/127 (21%)
Query: 4 AGGGEETPAPE---APHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLAD 60
A GEE A E A PQ A P+E + ++ S+E + A E S + +
Sbjct: 216 AAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPP--------ASDETKAAEEPSK-VEE 266
Query: 61 KLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPS------PSGEA 114
K E S ++P++ G A P E P EPA + PS EA
Sbjct: 267 KKAEEAGASAAACEAPSAAGPG---------APPEQEAAPAEEPAAAAASSACAAPSQEA 317
Query: 115 DGDCAPE 121
+C+PE
Sbjct: 318 QPECSPE 324
Score = 32.3 bits (72), Expect = 1.6
Identities = 44/175 (25%), Positives = 60/175 (34%), Gaps = 28/175 (16%)
Query: 2 EDAGGGEETPAPEAPHPPQ------LAPPEEQGLLFQEETIDLGGDEFGSEENETASEGS 55
++AG G E AP A A E G E+ G + EE + G
Sbjct: 176 KEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG---AAGG 232
Query: 56 SPLADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEAD 115
P K E+ + + P + + + EP + E AG + + EA
Sbjct: 233 DPQEAK----PQEAAVAPEKPPASDET------KAAEEPSKVEEKKAEEAGASAAACEAP 282
Query: 116 GDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPA 170
P A P AP ++ A S A P QE P C S APPA
Sbjct: 283 SAAGP-GAPPEQEAAPAEEPAAAAASSACAAPSQEAQ-----PEC---SPEAPPA 328
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 48.1 bits (113), Expect = 3e-05
Identities = 56/214 (26%), Positives = 69/214 (32%), Gaps = 19/214 (8%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDA 135
P +G+ G G + G +GD G G P G+ P P+ G P D
Sbjct: 184 PGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDG 243
Query: 136 AREVPG--SEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPS----FGGAS 189
PG E+ P P EP V + PP P P G
Sbjct: 244 LPGAPGDKGESGPPGVPGPRGEPGAV----GPKGPPGVDGVGVPGAAGLPGPQGPSGAKG 299
Query: 190 EASARTPPQVVQPS----PSLSTFFGD--TAASHSLASDFFDSFTTSAFISVSNPGAGSP 243
E R PP ++ P+ P L GD A L D + G G P
Sbjct: 300 EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
Query: 244 APASPPPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
P P +PG G P P GP PP P
Sbjct: 360 -PGLPGSAGLPGRRGPPGPKGEAGP--GGPPGVP 390
Score = 40.4 bits (93), Expect = 0.006
Identities = 49/208 (23%), Positives = 62/208 (29%), Gaps = 26/208 (12%)
Query: 73 SDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPR 132
S P G G+ G V + PG +G P AG P P G + P P P
Sbjct: 254 SGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPT 313
Query: 133 QDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGG--ASE 190
+PG + R P V + R P G+ EP GG
Sbjct: 314 GYGMPGLPGPKGDR--------GPAGVPGLLGDRGEP--GEDGEPGEQGPQGLGGPPGLP 363
Query: 191 ASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPP 250
SA P + P P G + D P + P P
Sbjct: 364 GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD-------------QGPSGLAGKPGVPGE 410
Query: 251 LAVPGTEGRPEPVAMRG-PQAAAPPASP 277
+PG G P P +G P P P
Sbjct: 411 RGLPGAHGPPGPTGPKGEPGFTGRPGGP 438
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/199 (25%), Positives = 63/199 (31%), Gaps = 60/199 (30%)
Query: 80 GDAGDLGRVRDEAEPGGEGDPG----------PEPAGTPSPSGEADGDCAPEDAAPSSGG 129
G G G+V +PG G+PG P P G P PSG
Sbjct: 126 GPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT--------------- 170
Query: 130 APRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGAS 189
P + A+ VPG + E P EP P R +P + +P GGA
Sbjct: 171 IPGKPGAQGVPGPPGFQGEPGPQ-GEPGPP----GDRGLKGDNGVGQPGLPGAPGQGGAP 225
Query: 190 EASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPP 249
PP + P+ L D PGA S P
Sbjct: 226 -----GPPGLPGPA--------------GLGKPGLDGL----------PGAPGDKGESGP 256
Query: 250 PLAVPGTEGRPEPVAMRGP 268
P VPG G P V +GP
Sbjct: 257 P-GVPGPRGEPGAVGPKGP 274
Score = 32.0 bits (71), Expect = 2.1
Identities = 17/41 (41%), Positives = 18/41 (43%), Gaps = 4/41 (9%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPG----PEPAGTPSPSG 112
P EG AG+ G PG G PG P P G P P G
Sbjct: 491 PPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG 531
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 48.1 bits (113), Expect = 3e-05
Identities = 72/296 (24%), Positives = 97/296 (32%), Gaps = 32/296 (10%)
Query: 9 ETPAPEAPHPPQLAPPEEQ-GLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHMM 67
+ P P+A PPQ P+ GL E I LG + TA L L +
Sbjct: 649 QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP---TAILTQDSLQMFLPQERS 705
Query: 68 ESVLISDSPN----------SEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGD 117
+ L ++ P+ + A D A+ G G P+ +P+P+ +
Sbjct: 706 QQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA 765
Query: 118 CAPEDAAPSSGG-----APRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRA----- 167
+ PSS AP D+ +P RP PP + P V S+
Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPH-LPSPHPTRPPSRPP-SRPQSVSRPPSEPPLHPCP 823
Query: 168 PPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSF 227
PP + V G AS P P P L A S
Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSS 883
Query: 228 TTSAFISVSNPGAGSPAPASP------PPLAVPGTEGRPEPVAMRGPQAAAPPASP 277
T+SA S S + PAP PP P P P P+ AAPP P
Sbjct: 884 TSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPP 939
Score = 35.8 bits (81), Expect = 0.15
Identities = 43/184 (23%), Positives = 65/184 (35%), Gaps = 18/184 (9%)
Query: 102 PEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCT 161
P+ P+ A G+ AP + AP + G + +P+ + P P P
Sbjct: 599 PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQ--QPQAQQPPQAPTPQAA 656
Query: 162 IFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLAS 221
Q P G + SP + + TP ++ SL F + L++
Sbjct: 657 APPQATTPQPSPG----LASSPEKIVLGQPPSATPTAILTQD-SLQMFLPQERSQQPLSA 711
Query: 222 DFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFA 281
+ ++ I + P A PAPA+P A GPQA ASP P
Sbjct: 712 EGPHLSVPASVIVSAPPPAQDPAPATPVAKG-----------AGLGPQAPDSQASPAPAP 760
Query: 282 HIQA 285
I A
Sbjct: 761 QIPA 764
Score = 32.7 bits (73), Expect = 1.2
Identities = 62/214 (28%), Positives = 79/214 (36%), Gaps = 45/214 (21%)
Query: 99 DPGPEPAGTPSPSGEADG------DCAPE----DAAPSSGGAPRQDAAREVPGSEAARPE 148
+P P P P P+G+ +G APE AP P + RE G A PE
Sbjct: 1344 EPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA-PE 1402
Query: 149 QEP----------PVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASART--- 195
P P+ V T R A D +M+K P A+ A+ T
Sbjct: 1403 GTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
Query: 196 -------PPQVVQPSPSLSTFFGDTA--ASHSLASDFFDSFTTSAFISVSN----PGAGS 242
PP + S S D A +S S D SA S+ N PG +
Sbjct: 1463 DWEAPGLPPAKRRKSESPDV---DQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGR-T 1518
Query: 243 PAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPAS 276
PAP S P A GT P P + P+ A PP+S
Sbjct: 1519 PAP-SYPHAASAGTPASPPP--LHRPE-AYPPSS 1548
Score = 32.0 bits (71), Expect = 2.1
Identities = 43/149 (28%), Positives = 48/149 (32%), Gaps = 27/149 (18%)
Query: 151 PPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSP-SFGGASEASARTPPQVVQPSPSLS-- 207
PP +P P P A G G PQ S S A + A P + PS S S
Sbjct: 728 PPAQDPAPA-------TPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLP 780
Query: 208 --TFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPP--------------- 250
GD+ S S S SVS P + P PPP
Sbjct: 781 HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ 840
Query: 251 LAVPGTEGRPEPVAMRGPQAAAPPASPEP 279
L VP P P A PQ P S P
Sbjct: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQPP 869
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/283 (21%), Positives = 80/283 (28%), Gaps = 70/283 (24%)
Query: 5 GGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNE 64
GG + P P PQ PP+ GG++ +G P D +
Sbjct: 125 GGNQPQGPPPPPGKPQGPPPQ-------------GGNKPQGPPPPGKPQGPPPQGDNKSR 171
Query: 65 HMMESVLISDSPNSEGDAGDLGRVRDEAEP------GGEGDPGPEPAGTPS---PSGEAD 115
P +G G +P GG GP P G P P G+
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 116 GDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGF 175
A G P+ + P +P+ PP P + PP G
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-------QGPPPPGKPQ 284
Query: 176 EPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISV 235
P P GG+ S+R+PP Q P
Sbjct: 285 GP-----PPQGGSKSRSSRSPPGKPQGPP------------------------------- 308
Query: 236 SNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P G+ PPP PG P P PQ PP P+
Sbjct: 309 --PQGGNQPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQ 346
Score = 45.8 bits (107), Expect = 1e-04
Identities = 53/221 (23%), Positives = 68/221 (30%), Gaps = 15/221 (6%)
Query: 59 ADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDP-GPEPAGTPSPSGEADGD 117
A LNE + + S + A G + + P G P GP P G P G
Sbjct: 16 AQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP 75
Query: 118 CAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEP 177
P+ P G P+ PG +P+ PP + S R+PP G P
Sbjct: 76 GKPQGPPPQGGNKPQ---GPPPPG----KPQGPPPQGDKSR-----SPRSPPGKPQGPPP 123
Query: 178 QMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSN 237
Q P + PP P G + S +
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 238 PGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P G P PPP PG P P PQ PP P+
Sbjct: 184 PPQGGNQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Score = 37.0 bits (84), Expect = 0.066
Identities = 46/201 (22%), Positives = 65/201 (32%), Gaps = 31/201 (15%)
Query: 6 GGEETPAPEAPHPPQLAPP---EEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKL 62
G + P P+ + PQ PP + QG Q G G + GS + +
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Query: 63 NEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPED 122
+ +G G+ + GG GP P G P
Sbjct: 300 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ------------- 346
Query: 123 AAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKS 182
P G + +AR PG P+QE + P PPA G+ PQ ++
Sbjct: 347 -GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP---------PPAGGN---PQQPQA 393
Query: 183 PSFGGASEASARTPPQVVQPS 203
P G PPQ +PS
Sbjct: 394 PPAG--QPQGPPRPPQGGRPS 412
Score = 35.8 bits (81), Expect = 0.15
Identities = 55/231 (23%), Positives = 70/231 (30%), Gaps = 63/231 (27%)
Query: 76 PNSEGDAGDLGRVRDEAEPGGEGDPGPE----PAGTPSPSGEADG--------------D 117
P GD + PG P P+ P G P P G+ G
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280
Query: 118 CAPEDAAPSSGGAPRQDAAREVPGSEAARPEQ---EPPVAEPVPVCTIFSQRAPPASGDG 174
P+ P G R ++R PG P Q +P P P + PP G G
Sbjct: 281 GKPQGPPPQGGSKSR--SSRSPPGKPQGPPPQGGNQPQGPPPPP----GKPQGPPPQG-G 333
Query: 175 FEPQMVKSPS-------FGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSF 227
+PQ P GG+ SAR+PP Q P G+
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE---GNNPQ------------ 378
Query: 228 TTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPE 278
P G+P PP P +G P P PQ P P+
Sbjct: 379 ------GPPPPAGGNPQQPQAPPAGQP--QGPPRP-----PQGGRPSRPPQ 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,676,319
Number of Sequences: 37866
Number of extensions: 1924305
Number of successful extensions: 20110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 199
Number of HSP's successfully gapped in prelim test: 1099
Number of HSP's that attempted gapping in prelim test: 11503
Number of HSP's gapped (non-prelim): 7038
length of query: 735
length of database: 18,247,518
effective HSP length: 110
effective length of query: 625
effective length of database: 14,082,258
effective search space: 8801411250
effective search space used: 8801411250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.